LOCUS       DAXLPY010000001       145749 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.001, whole genome shotgun sequence.
ACCESSION   DAXLPY010000001 DAXLPY010000000
VERSION     DAXLPY010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 145749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 145749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..145749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.001"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="ACF3UF_000001"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="ACF3UF_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFD3670168.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="ACF3UF_000002"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="ACF3UF_000002"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFD3670169.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="ACF3UF_000003"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="ACF3UF_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFD3670170.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="ACF3UF_000004"
     CDS             complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="ACF3UF_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFD3670171.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="ACF3UF_000005"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="ACF3UF_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFD3670172.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="ACF3UF_000006"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="ACF3UF_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFD3670173.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="ACF3UF_000007"
     CDS             complement(8557..9027)
                     /locus_tag="ACF3UF_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFD3670174.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="ACF3UF_000008"
     CDS             complement(9073..9498)
                     /locus_tag="ACF3UF_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFD3670175.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="ACF3UF_000009"
     CDS             complement(9565..9834)
                     /locus_tag="ACF3UF_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFD3670176.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="ACF3UF_000010"
     CDS             complement(9845..11440)
                     /locus_tag="ACF3UF_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3670177.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="ACF3UF_000011"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="ACF3UF_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFD3670178.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVSDQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /gene="pth"
                     /locus_tag="ACF3UF_000012"
     CDS             complement(14993..15553)
                     /gene="pth"
                     /locus_tag="ACF3UF_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFD3670179.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="ACF3UF_000013"
     CDS             15906..16880
                     /locus_tag="ACF3UF_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFD3670180.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="ACF3UF_000014"
     CDS             17050..18450
                     /locus_tag="ACF3UF_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFD3670181.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="ACF3UF_000015"
     CDS             complement(18528..19250)
                     /locus_tag="ACF3UF_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3670182.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="ACF3UF_000016"
     CDS             complement(19329..19835)
                     /locus_tag="ACF3UF_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3670183.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="ACF3UF_000017"
     CDS             19958..21757
                     /locus_tag="ACF3UF_000017"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFD3670184.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21825..23399)
                     /locus_tag="ACF3UF_000018"
     CDS             complement(21825..23399)
                     /locus_tag="ACF3UF_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFD3670185.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="ACF3UF_000019"
     CDS             complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="ACF3UF_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFD3670186.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="ACF3UF_000020"
     CDS             complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="ACF3UF_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFD3670187.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25176..25814)
                     /locus_tag="ACF3UF_000021"
     CDS             complement(25176..25814)
                     /locus_tag="ACF3UF_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFD3670188.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25815..26465)
                     /gene="rpe"
                     /locus_tag="ACF3UF_000022"
     CDS             complement(25815..26465)
                     /gene="rpe"
                     /locus_tag="ACF3UF_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFD3670189.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="ACF3UF_000023"
     CDS             complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="ACF3UF_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFD3670190.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27542..29611)
                     /gene="pknB"
                     /locus_tag="ACF3UF_000024"
     CDS             complement(27542..29611)
                     /gene="pknB"
                     /locus_tag="ACF3UF_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFD3670191.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29608..30348)
                     /locus_tag="ACF3UF_000025"
     CDS             complement(29608..30348)
                     /locus_tag="ACF3UF_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFD3670192.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30361..31719)
                     /gene="rsmB"
                     /locus_tag="ACF3UF_000026"
     CDS             complement(30361..31719)
                     /gene="rsmB"
                     /locus_tag="ACF3UF_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFD3670193.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31719..32657)
                     /gene="fmt"
                     /locus_tag="ACF3UF_000027"
     CDS             complement(31719..32657)
                     /gene="fmt"
                     /locus_tag="ACF3UF_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFD3670194.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32650..33141)
                     /gene="def"
                     /locus_tag="ACF3UF_000028"
     CDS             complement(32650..33141)
                     /gene="def"
                     /locus_tag="ACF3UF_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFD3670195.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33156..35564)
                     /gene="priA"
                     /locus_tag="ACF3UF_000029"
     CDS             complement(33156..35564)
                     /gene="priA"
                     /locus_tag="ACF3UF_000029"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFD3670196.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35817..36122)
                     /gene="rpoZ"
                     /locus_tag="ACF3UF_000030"
     CDS             complement(35817..36122)
                     /gene="rpoZ"
                     /locus_tag="ACF3UF_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFD3670197.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36127..36741)
                     /gene="gmk"
                     /locus_tag="ACF3UF_000031"
     CDS             complement(36127..36741)
                     /gene="gmk"
                     /locus_tag="ACF3UF_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFD3670198.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37228..37512)
                     /locus_tag="ACF3UF_000032"
     CDS             complement(37228..37512)
                     /locus_tag="ACF3UF_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670199.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37530..38420)
                     /locus_tag="ACF3UF_000033"
     CDS             complement(37530..38420)
                     /locus_tag="ACF3UF_000033"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFD3670200.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38440..38658)
                     /locus_tag="ACF3UF_000034"
     CDS             complement(38440..38658)
                     /locus_tag="ACF3UF_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFD3670201.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38628..40328)
                     /locus_tag="ACF3UF_000035"
     CDS             complement(38628..40328)
                     /locus_tag="ACF3UF_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFD3670202.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40595..41368
                     /locus_tag="ACF3UF_000036"
     CDS             40595..41368
                     /locus_tag="ACF3UF_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670203.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41449..42018)
                     /gene="thiT"
                     /locus_tag="ACF3UF_000037"
     CDS             complement(41449..42018)
                     /gene="thiT"
                     /locus_tag="ACF3UF_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFD3670204.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42084..42186)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42192..43163)
                     /locus_tag="ACF3UF_000038"
     CDS             complement(42192..43163)
                     /locus_tag="ACF3UF_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFD3670205.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43257..44630)
                     /gene="glmU"
                     /locus_tag="ACF3UF_000039"
     CDS             complement(43257..44630)
                     /gene="glmU"
                     /locus_tag="ACF3UF_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFD3670206.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45133..45951)
                     /gene="purR"
                     /locus_tag="ACF3UF_000040"
     CDS             complement(45133..45951)
                     /gene="purR"
                     /locus_tag="ACF3UF_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFD3670207.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46118..46942)
                     /locus_tag="ACF3UF_000041"
     CDS             complement(46118..46942)
                     /locus_tag="ACF3UF_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFD3670208.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46915..47595)
                     /locus_tag="ACF3UF_000042"
     CDS             complement(46915..47595)
                     /locus_tag="ACF3UF_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3670209.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47618..48556)
                     /locus_tag="ACF3UF_000043"
     CDS             complement(47618..48556)
                     /locus_tag="ACF3UF_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFD3670210.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48801..49652)
                     /gene="ispE"
                     /locus_tag="ACF3UF_000044"
     CDS             complement(48801..49652)
                     /gene="ispE"
                     /locus_tag="ACF3UF_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFD3670211.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49806..52379)
                     /gene="mprF"
                     /locus_tag="ACF3UF_000045"
     CDS             complement(49806..52379)
                     /gene="mprF"
                     /locus_tag="ACF3UF_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFD3670212.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52520..53326
                     /gene="proC"
                     /locus_tag="ACF3UF_000046"
     CDS             52520..53326
                     /gene="proC"
                     /locus_tag="ACF3UF_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFD3670213.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53405..54961)
                     /gene="rny"
                     /locus_tag="ACF3UF_000047"
     CDS             complement(53405..54961)
                     /gene="rny"
                     /locus_tag="ACF3UF_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFD3670214.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55372..56421)
                     /gene="recA"
                     /locus_tag="ACF3UF_000048"
     CDS             complement(55372..56421)
                     /gene="recA"
                     /locus_tag="ACF3UF_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFD3670215.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56530..57771)
                     /locus_tag="ACF3UF_000049"
     CDS             complement(56530..57771)
                     /locus_tag="ACF3UF_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFD3670216.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(58011..58589)
                     /gene="pgsA"
                     /locus_tag="ACF3UF_000050"
     CDS             complement(58011..58589)
                     /gene="pgsA"
                     /locus_tag="ACF3UF_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFD3670217.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58798..59721)
                     /locus_tag="ACF3UF_000051"
     CDS             complement(58798..59721)
                     /locus_tag="ACF3UF_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFD3670218.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60460..61746)
                     /locus_tag="ACF3UF_000052"
     CDS             complement(60460..61746)
                     /locus_tag="ACF3UF_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFD3670219.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61739..63007)
                     /locus_tag="ACF3UF_000053"
     CDS             complement(61739..63007)
                     /locus_tag="ACF3UF_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFD3670220.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63259..63720
                     /gene="mscL"
                     /locus_tag="ACF3UF_000054"
     CDS             63259..63720
                     /gene="mscL"
                     /locus_tag="ACF3UF_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFD3670221.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63779..64225)
                     /locus_tag="ACF3UF_000055"
     CDS             complement(63779..64225)
                     /locus_tag="ACF3UF_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3670222.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64318..64563)
                     /locus_tag="ACF3UF_000056"
     CDS             complement(64318..64563)
                     /locus_tag="ACF3UF_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFD3670223.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64678..65256)
                     /locus_tag="ACF3UF_000057"
     CDS             complement(64678..65256)
                     /locus_tag="ACF3UF_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFD3670224.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65333..65863)
                     /locus_tag="ACF3UF_000058"
     CDS             complement(65333..65863)
                     /locus_tag="ACF3UF_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFD3670225.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65867..66727)
                     /gene="rlmB"
                     /locus_tag="ACF3UF_000059"
     CDS             complement(65867..66727)
                     /gene="rlmB"
                     /locus_tag="ACF3UF_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFD3670226.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66720..67115)
                     /locus_tag="ACF3UF_000060"
     CDS             complement(66720..67115)
                     /locus_tag="ACF3UF_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFD3670227.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67112..68524)
                     /gene="cysS"
                     /locus_tag="ACF3UF_000061"
     CDS             complement(67112..68524)
                     /gene="cysS"
                     /locus_tag="ACF3UF_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFD3670228.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68521..69057)
                     /gene="epsC"
                     /locus_tag="ACF3UF_000062"
     CDS             complement(68521..69057)
                     /gene="epsC"
                     /locus_tag="ACF3UF_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFD3670229.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69143..69382)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69379..70839)
                     /gene="gltX"
                     /locus_tag="ACF3UF_000063"
     CDS             complement(69379..70839)
                     /gene="gltX"
                     /locus_tag="ACF3UF_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFD3670230.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(71009..72166)
                     /locus_tag="ACF3UF_000064"
     CDS             complement(71009..72166)
                     /locus_tag="ACF3UF_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFD3670231.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72200..73570)
                     /gene="radA"
                     /locus_tag="ACF3UF_000065"
     CDS             complement(72200..73570)
                     /gene="radA"
                     /locus_tag="ACF3UF_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFD3670232.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73633..74160)
                     /locus_tag="ACF3UF_000066"
     CDS             complement(73633..74160)
                     /locus_tag="ACF3UF_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFD3670233.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74390..75196
                     /gene="proB"
                     /locus_tag="ACF3UF_000067"
     CDS             74390..75196
                     /gene="proB"
                     /locus_tag="ACF3UF_000067"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFD3670234.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            75193..76440
                     /locus_tag="ACF3UF_000068"
     CDS             75193..76440
                     /locus_tag="ACF3UF_000068"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFD3670235.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76516..76860
                     /locus_tag="ACF3UF_000069"
     CDS             76516..76860
                     /locus_tag="ACF3UF_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670236.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76977..77303)
                     /locus_tag="ACF3UF_000070"
     CDS             complement(76977..77303)
                     /locus_tag="ACF3UF_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670237.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77918..79120)
                     /locus_tag="ACF3UF_000071"
     CDS             complement(77918..79120)
                     /locus_tag="ACF3UF_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3670238.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            79237..79752
                     /locus_tag="ACF3UF_000072"
     CDS             79237..79752
                     /locus_tag="ACF3UF_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3670239.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79951..80397)
                     /locus_tag="ACF3UF_000073"
     CDS             complement(79951..80397)
                     /locus_tag="ACF3UF_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFD3670240.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80444..81922)
                     /gene="msr(C)"
                     /locus_tag="ACF3UF_000074"
     CDS             complement(80444..81922)
                     /gene="msr(C)"
                     /locus_tag="ACF3UF_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFD3670241.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82276..82905)
                     /locus_tag="ACF3UF_000075"
     CDS             complement(82276..82905)
                     /locus_tag="ACF3UF_000075"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFD3670242.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(82889..83353)
                     /locus_tag="ACF3UF_000076"
     CDS             complement(82889..83353)
                     /locus_tag="ACF3UF_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3670243.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83840..85108)
                     /locus_tag="ACF3UF_000077"
     CDS             complement(83840..85108)
                     /locus_tag="ACF3UF_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFD3670244.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85339..86076)
                     /locus_tag="ACF3UF_000078"
     CDS             complement(85339..86076)
                     /locus_tag="ACF3UF_000078"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3670245.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(86143..86712)
                     /locus_tag="ACF3UF_000079"
     CDS             complement(86143..86712)
                     /locus_tag="ACF3UF_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFD3670246.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86840..87712
                     /locus_tag="ACF3UF_000080"
     CDS             86840..87712
                     /locus_tag="ACF3UF_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3670247.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            88054..88926
                     /locus_tag="ACF3UF_000081"
     CDS             88054..88926
                     /locus_tag="ACF3UF_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFD3670248.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88923..90881
                     /gene="nagE"
                     /locus_tag="ACF3UF_000082"
     CDS             88923..90881
                     /gene="nagE"
                     /locus_tag="ACF3UF_000082"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFD3670249.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(91213..92064)
                     /locus_tag="ACF3UF_000083"
     CDS             complement(91213..92064)
                     /locus_tag="ACF3UF_000083"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3670250.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            92187..92654
                     /locus_tag="ACF3UF_000084"
     CDS             92187..92654
                     /locus_tag="ACF3UF_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFD3670251.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92917..93399)
                     /locus_tag="ACF3UF_000085"
     CDS             complement(92917..93399)
                     /locus_tag="ACF3UF_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFD3670252.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93499..94362)
                     /locus_tag="ACF3UF_000086"
     CDS             complement(93499..94362)
                     /locus_tag="ACF3UF_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFD3670253.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            94960..95835
                     /locus_tag="ACF3UF_000087"
     CDS             94960..95835
                     /locus_tag="ACF3UF_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFD3670254.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(95980..96132)
                     /locus_tag="ACF3UF_000088"
                     /pseudo
     CDS             complement(95980..96132)
                     /locus_tag="ACF3UF_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(96400..97731)
                     /locus_tag="ACF3UF_000089"
     CDS             complement(96400..97731)
                     /locus_tag="ACF3UF_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3670255.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(97880..98593)
                     /locus_tag="ACF3UF_000090"
     CDS             complement(97880..98593)
                     /locus_tag="ACF3UF_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3670256.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            98768..100192
                     /locus_tag="ACF3UF_000091"
     CDS             98768..100192
                     /locus_tag="ACF3UF_000091"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3670257.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100491..101198
                     /locus_tag="ACF3UF_000092"
     CDS             100491..101198
                     /locus_tag="ACF3UF_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFD3670258.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            101185..101508
                     /locus_tag="ACF3UF_000093"
     CDS             101185..101508
                     /locus_tag="ACF3UF_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFD3670259.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101597..102634)
                     /locus_tag="ACF3UF_000094"
     CDS             complement(101597..102634)
                     /locus_tag="ACF3UF_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFD3670260.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(102955..103938)
                     /locus_tag="ACF3UF_000095"
     CDS             complement(102955..103938)
                     /locus_tag="ACF3UF_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFD3670261.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(104353..105123)
                     /locus_tag="ACF3UF_000096"
     CDS             complement(104353..105123)
                     /locus_tag="ACF3UF_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3670262.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(105116..106051)
                     /locus_tag="ACF3UF_000097"
     CDS             complement(105116..106051)
                     /locus_tag="ACF3UF_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670263.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(106367..108016)
                     /locus_tag="ACF3UF_000098"
     CDS             complement(106367..108016)
                     /locus_tag="ACF3UF_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFD3670264.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(108133..110736)
                     /locus_tag="ACF3UF_000099"
     CDS             complement(108133..110736)
                     /locus_tag="ACF3UF_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFD3670265.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(110748..111797)
                     /locus_tag="ACF3UF_000100"
     CDS             complement(110748..111797)
                     /locus_tag="ACF3UF_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFD3670266.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(111823..112137)
                     /locus_tag="ACF3UF_000101"
     CDS             complement(111823..112137)
                     /locus_tag="ACF3UF_000101"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFD3670267.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(112153..112599)
                     /locus_tag="ACF3UF_000102"
     CDS             complement(112153..112599)
                     /locus_tag="ACF3UF_000102"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFD3670268.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(112600..114522)
                     /locus_tag="ACF3UF_000103"
     CDS             complement(112600..114522)
                     /locus_tag="ACF3UF_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3670269.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(114734..115630)
                     /locus_tag="ACF3UF_000104"
     CDS             complement(114734..115630)
                     /locus_tag="ACF3UF_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3670270.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(115623..116303)
                     /locus_tag="ACF3UF_000105"
     CDS             complement(115623..116303)
                     /locus_tag="ACF3UF_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3670271.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(116304..117086)
                     /locus_tag="ACF3UF_000106"
     CDS             complement(116304..117086)
                     /locus_tag="ACF3UF_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFD3670272.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(117079..117996)
                     /locus_tag="ACF3UF_000107"
     CDS             complement(117079..117996)
                     /locus_tag="ACF3UF_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3670273.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(118160..118414)
                     /locus_tag="ACF3UF_000108"
     CDS             complement(118160..118414)
                     /locus_tag="ACF3UF_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670274.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
     gene            119271..122498
                     /gene="fss3"
                     /locus_tag="ACF3UF_000109"
     CDS             119271..122498
                     /gene="fss3"
                     /locus_tag="ACF3UF_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFD3670275.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            122611..122925
                     /locus_tag="ACF3UF_000110"
     CDS             122611..122925
                     /locus_tag="ACF3UF_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFD3670276.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            122938..123312
                     /locus_tag="ACF3UF_000111"
     CDS             122938..123312
                     /locus_tag="ACF3UF_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFD3670277.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            123322..123657
                     /locus_tag="ACF3UF_000112"
     CDS             123322..123657
                     /locus_tag="ACF3UF_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFD3670278.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            123740..125080
                     /locus_tag="ACF3UF_000113"
     CDS             123740..125080
                     /locus_tag="ACF3UF_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFD3670279.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            125158..125832
                     /locus_tag="ACF3UF_000114"
     CDS             125158..125832
                     /locus_tag="ACF3UF_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFD3670280.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            125825..125989
                     /locus_tag="ACF3UF_000115"
     CDS             125825..125989
                     /locus_tag="ACF3UF_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670281.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            126065..127207
                     /gene="dcm"
                     /locus_tag="ACF3UF_000116"
                     /pseudo
     CDS             126065..127207
                     /gene="dcm"
                     /locus_tag="ACF3UF_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            127197..127487
                     /locus_tag="ACF3UF_000117"
     CDS             127197..127487
                     /locus_tag="ACF3UF_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670282.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            127746..128930
                     /gene="mobT"
                     /locus_tag="ACF3UF_000118"
     CDS             127746..128930
                     /gene="mobT"
                     /locus_tag="ACF3UF_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFD3670283.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            128927..129064
                     /locus_tag="ACF3UF_000119"
     CDS             128927..129064
                     /locus_tag="ACF3UF_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFD3670284.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            129810..131720
                     /gene="ltrA"
                     /locus_tag="ACF3UF_000120"
     CDS             129810..131720
                     /gene="ltrA"
                     /locus_tag="ACF3UF_000120"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFD3670285.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            131824..132048
                     /locus_tag="ACF3UF_000121"
     CDS             131824..132048
                     /locus_tag="ACF3UF_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670286.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            132061..132564
                     /locus_tag="ACF3UF_000122"
     CDS             132061..132564
                     /locus_tag="ACF3UF_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFD3670287.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            132624..133013
                     /locus_tag="ACF3UF_000123"
     CDS             132624..133013
                     /locus_tag="ACF3UF_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFD3670288.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            133000..135447
                     /locus_tag="ACF3UF_000124"
     CDS             133000..135447
                     /locus_tag="ACF3UF_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3670289.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            135452..137575
                     /locus_tag="ACF3UF_000125"
     CDS             135452..137575
                     /locus_tag="ACF3UF_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFD3670290.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            137572..138576
                     /locus_tag="ACF3UF_000126"
     CDS             137572..138576
                     /locus_tag="ACF3UF_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFD3670291.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            138595..139506
                     /locus_tag="ACF3UF_000127"
     CDS             138595..139506
                     /locus_tag="ACF3UF_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFD3670292.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            139693..139949
                     /locus_tag="ACF3UF_000128"
                     /pseudo
     CDS             139693..139949
                     /locus_tag="ACF3UF_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(140166..140381)
                     /locus_tag="ACF3UF_000129"
     CDS             complement(140166..140381)
                     /locus_tag="ACF3UF_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670293.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(140630..140848)
                     /locus_tag="ACF3UF_000130"
                     /pseudo
     CDS             complement(140630..140848)
                     /locus_tag="ACF3UF_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            complement(141143..142582)
                     /locus_tag="ACF3UF_000131"
     CDS             complement(141143..142582)
                     /locus_tag="ACF3UF_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3670294.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            complement(143170..143802)
                     /locus_tag="ACF3UF_000132"
     CDS             complement(143170..143802)
                     /locus_tag="ACF3UF_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFD3670295.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            complement(144151..145602)
                     /locus_tag="ACF3UF_000133"
     CDS             complement(144151..145602)
                     /locus_tag="ACF3UF_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3670296.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
BASE COUNT        42573 a        29959 c        26545 g        46672 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta ccataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttcccctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg gaatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctcctccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgacacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta cacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagcttttac atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggttga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ctgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttgattaatc attcttacat gctgacagca
    21841 aagtcagggg caaaccattg aactgaacca acttttacgc tttcgcctgg ttgaggagca
    21901 tggatatatt gtcctccgcc taaagcaatc gctacgtggt aagttccgcc ttgtgacccc
    21961 cagaataaca agtctccagc ttttgcttga gaaactgaaa tttttgttcc agctgattct
    22021 tgaggaactg tccaaccacc gatgtcacga ccagttactt gcatgtaaac atagcgtgtg
    22081 aaccctgagc agtcaaagcc acttggatct ttaccgcccc aaacatatgg agtaccaata
    22141 tatttgtaag cttctgctac gattgctgca ccattcacac ttccagaagg agctggagca
    22201 ggtgttacag gttttggttg ttcaggtgtt ggtgttggcg ttggagccgg agtactactt
    22261 cctgtgccgt ttcctgtatc aacactttga tctgttgatg gtgttgtagg cgcaggtgtt
    22321 gttgattctt ctgttgttga agattcaggc actgttgttg attcttctgt tgctgaagat
    22381 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcgctgttgt tgattcttct
    22441 gttgctgaag attcaggcgc tgttgattct tctgttgaag attcaggtgt tgttgattct
    22501 tctgttgctg aagattgtgt agctgatgat gattcttcag tcattgaaga ttgtgtagct
    22561 gatgattctt ctgttgctga gctttgtgca gtagatgaag cttgagtagc ttgtgcttca
    22621 gcctctgctt gttcgcgtgc ttctttttca gctttttctt gtgcagcttg ttgacgagct
    22681 tgttctgcta gacgttgttg ttcacgaata cgagcttgct ctgcttcagc ttctgctttt
    22741 tgacggttca agtcagcttt cttgtcttca gcagttgctt gttcagcagc taatgaagtt
    22801 ttcagtacgt tcaaatcagc ttgtttagat aaaagatcgc ctttttgaga ttccaaagca
    22861 gcttggtttt cagctaattc ttttagttta gcatcgtttt cagctttttt gtcttctaca
    22921 gcttttttat cttgtttttg ttgttccatc aagtcgttgt ttgcttttac catcgttgtc
    22981 attgcttgaa cgcgtccaat agcatctgct aatgaatcag cattcaatac agcatcgatg
    23041 tagtttgagc ttgtgttgct tacttgtgct tcgcgtgctt gtttttggat tgtatcttca
    23101 cgtttttcaa tacgttcttg taaatctgca atgtctttta ctaattgtgc agattcttga
    23161 cgcaatgtat cttgttttgc taataggtct tgtgcttgtg tgttgatttc agaaacttgg
    23221 ctttctaagg catcgatttg tgattgtgca tctgcttgtt gatttttcaa gtctgcaatc
    23281 ttttgatctt gctgttgtat ctgagaatca aaatcgtccg ccgcggcagc gatcggtgat
    23341 gctacggcag tcaaggtcat tgaacatacc attactgctg atattaaact ctttttcact
    23401 cttcattcct ccgactggct taatttaata aatatctaaa tatatttaag tctttcttaa
    23461 cgatataaaa attgtaccat agcagtgtgt caacgatata atagttatgt tacaaaaatg
    23521 tttcaaaaca acttttaaaa atgacaaaac tgttcgtttc agaaaatgat catgaaaaag
    23581 ccgcgttaag tctagcattt cttaagataa caacgattct ttttcgcttt cgacctaaaa
    23641 ataaaaaaag aaattattca tcactgaata atttcttaaa gggaaaaatg aataatacaa
    23701 atataatcat gttcaacagc agtgtaggtc ctaaaaacct tgtaataaaa tacgtgttat
    23761 ttactactgc taatttaaaa atcaactgga ccaccatcgt aaacaattca taacccgtga
    23821 caaagatgat catactgaaa aattcagtaa agatgttgac atggataacg tctttcatta
    23881 catacatcaa ccatacaatt aaagggagag ctactgcata gataccgata acgccaatat
    23941 agtaagcgtc atagatagcc ccgagaacaa tcgtggtaat cagtaaataa cgtttttcaa
    24001 acgccatact gcaacataat aatgccaata tcagaaagtg ggcatttgac atataggtgc
    24061 ctttcgacca ctcccctagc attcttgtta aatgaccatc tatcaacatc aaaaagaaca
    24121 aaacgattgg cagatagtac ttcattgttt ctttcttcaa catggactaa tcctccgcta
    24181 gccgttggac aatcgtcaca actgacacgt catacatttc tgcataaggt ttcacataaa
    24241 cttcccgatc cagcccataa ctatctggtt tcgttttaat aaccgtaccg atcggcaagt
    24301 tagctggaga attccctcca agaccggatg tctggacaac atccccttct ttgatatccg
    24361 tatcaccagt taattgggtc accactaagg catggagctt ttcatcatag tttttaagca
    24421 aaccaaacgc ttcgccatta gccgaagata cccgtactgg aaaatgattg gagctttcat
    24481 tagaggatga cagtaattcg attttagacg aagccgtatt gacctcgatc actcggccaa
    24541 tcaatccttt ttgcgacatg actgccatat ttgcttcgat accgtcttta gaacccttgt
    24601 ctacgatcag catgtcctgc caactgtcag gcgaacgagt aatgacattt gccgttactt
    24661 tttcgtaact agtcagcgtc tgattcaact caagttcttt tttcaacgct tcgatttctc
    24721 tctcgtaatt cttgttttgc tgtgaaacgt catcatagct atcgattttt tcttttagcc
    24781 gctcattttc ggcataagtt gaaaaaagat tatggacaga atctactcca tttcgtaccc
    24841 accgtactgg ggcagagatt gttttatcaa ccattgcaac actgtcatta acgatggatt
    24901 ggaagaaatt gggctttcct tcattcgctc gctgcgcagc ggtcacactt agtatcgtca
    24961 ccacgatgat aacaataacc aaggtaataa taatattttt attaggattg aacttcttca
    25021 caaagacacc tcgaattaat tagactcttg tgttcaattt tatcactaaa tgccgtgaaa
    25081 caaaaggtaa gttgctcctc ttaagctttt ttttagcaaa taatagattc tgtcattttt
    25141 agcctgaaag acaaattttt ttatttgttt atggatcaat ctttgctttg aataactgca
    25201 atcataccat ctgaaaaaga aaattctgcg gtatctgaaa gaaattcgtt acttgcataa
    25261 gatgtcggat attctacttc tttattttcc aatacatact tgctgccttt taatgtaaga
    25321 ttcgagacgg gagtcaagca gcaataagct aaatacttca tatctggtat ctgtcttact
    25381 atatgctctc caggcaaata ataagacaaa taattttgac aatctctgat aataagctga
    25441 tgggcaaagg gtttgaagcg aggttccata cctaaccaga gattggctaa aagatgatcc
    25501 aatcttccgc ccgtagctcc aatcaaagtg acttccgctt gcgggtaacg ttcaaatgtt
    25561 tttaagatac ctaactgtgt atctgtatcg tctttttctg caggggaacg ggtatactct
    25621 ttggcttttg caaatacttc cttctgctct tcgttcgaca atgaatcaaa atcacccact
    25681 gccagatcta ctgggtagcc tgcttgaagc aggtacagcg caccacggtc tatcccgaca
    25741 taggcatcgt atttggacag cagagactgc ggccagtttt gcggattacc tccagcagct
    25801 aataaaattt tcatttagtc taatgcctct tttaatcgtt cgatttgtcc gactggattt
    25861 tcggctccat agatatatga tcctgcaacg aagacatccg cccctgcatc tttacagatt
    25921 tttgctgttt ctggaacgat tccgccatct acttcgattg cataagtcca attgttctct
    25981 ctacgtagat cagcgagttc cgtaattttt tctactgttt cttcaataaa gctttgtccg
    26041 ccgaacccag gattgacagt catgactagt acttgatcag ccaaaggcaa aacatgtttg
    26101 atcatggaga ctggtgttcc tggattgata actactccag ctttaactcc taagcttttt
    26161 gtcatttgaa gtgcccgatg aatatgagga gttgcttcga cgtggacagt aatgatatct
    26221 gctccagctt ttgcaaatgc tggaatgtag ttttctggat caacgatcat cagatggacg
    26281 tctaacggta atttagtaac aggacggatt gcctgaacaa tatttggccc taatgtgata
    26341 tttgggacaa atcggccatc cattacatct acgtggatgt aatctgcgcc tcctttttcc
    26401 actaactcaa tgtctctttg taaattggca aaatctgcac tcaaaatgga tggtgctatc
    26461 ttcattcttg tttcctccta ttttcgttta ccttcttttt ttgcatacat tggttttctt
    26521 ttttcgattt cttgtaagaa ttgcaaataa ttgtcgtaac gtgtctgtgc gataccacct
    26581 gtttctactc tatgttttac ttcgcagcca ggttctttag catgcatgca ctctctaaat
    26641 ttgcaatgga cagaagcttc tacaaattca ggaaattgtc tcggcagttc tcctgcttca
    26701 attgtcaaaa agtcaatcga gctaaatcct ggtgtatctg ctactaaccc gccatagata
    26761 ggaatcagtt ccacatgacg tgttgtatgc cgtcctcttc caagtgcatc agaaatctct
    26821 cctgttgcta aattcagttc cggtgatatt tgattcagta gcgtcgattt tcctgctcca
    26881 gactgaccca taaagaccga tagccgttct gggaagtaac ggatcagttc tgtcgtatca
    26941 cccgtatgat tgggtacaat caccggatag cctattttag tataggtttg cttgatctct
    27001 tcgatttttt ctgggtcgtc tgacaagtcg gtctttgtca aaaaaataat cggttcgatc
    27061 gactcgtatt ccaaggtaac tagaaagcgg tcaagtagat tataagaaaa tgcaggctct
    27121 acgatacttg tgacaatgat tccaagatca acatttgtga ctggtgggcg aactaattga
    27181 ttttttctcg gcaagatttc cagaagatag ccgtctgttt gattttcact ctcaaagatc
    27241 acctgatctc cgacaagcgg cgtgattttc cgattccgga aatttcctct tcctcttgtt
    27301 tgataggtct ctccgtttgc gtatacatag taaaaaccgc tgattgcttt tctgatttgt
    27361 cctttgataa gtgccacctc cgtttttgtt tattttacca tacgaagagg aaagtaggtg
    27421 ttattccatg caaacttctc aaagtatatg gcttgaaaat tgatcaaaag agatagaaac
    27481 acaaaaaaga gaatgcaaca aatcaatgtc gcattccctt ctgatatatt ttattcagca
    27541 cttattttga actttctgag gtgctagctg atgaacttgt ggagctggaa gattcttctt
    27601 ttgaagagtt gcttgtgcta ctggagctac ttgagctgct agaactgtct gaagagtctt
    27661 tttcagaact agaagacgct ggatctggtc ctttagagta aattacgttc acaaccattc
    27721 ctttggtaat tgtcgttcct gcccctggta ctgtacgaat cactttatct ttatccaccg
    27781 tgtttgaata ttcggaagtc tcatgcccga tatattctgc accgacacta gctaaataac
    27841 tttgtgcttc gctttttgta tagccggaga tatcattcaa tttaggctct gttccttggc
    27901 ttacgacaaa attgatgtaa gtttcttctg ctacaacttc acccgaggct ggatcctgac
    27961 tgatgatcga acctgatggt acagtgtcgc tatagtcata agtagcacta atattattga
    28021 tattgaatcc ttgtgtaaca agccaattac gaacagtttc gtagttttct cctacatgac
    28081 tactcaaagt cactgtttct ggtcctttgc tgactgtgaa agtaatcgtg tctgttttag
    28141 gatcgacttc tgtatcttct gatggagatt gcgaaatgat cattccgctt tctacctctg
    28201 aactgaattc ctcttctttt tgaatcaagt cagcagaaaa ccctaattct ttcaaacttg
    28261 cttcggcatc ttcataactt ttaccactgt aatcatctaa tttgattttt ttcgtgccgc
    28321 tactaatata cagagtgact tcgcgttttt gcttgactgt cgttcccgct gccgggtctg
    28381 tcttcactac attaccttct tcgattttgt catctgcaat ttcttctgtt tttgttgcta
    28441 cttctaattt cgcttttgcg agtgtttctc tagcagaagc ttcagaaaga tcagaaacat
    28501 caggaacaac aacttctcct cgcccgccag aagcaaagaa tacagctgtt ccgattccta
    28561 aaacagcaag aatagctaat aggatcagcc accatttttt ctgtcctttc tttttaggat
    28621 caggcagaac ttcttcctcc tctggtaagg tttcgttttc tggcttgtct tttggcagag
    28681 gcatagattt gaatgaatca ggcattggtg catcttccgt aaggggtgtg ataacttttg
    28741 tttcattatc catcacatga ggctgccatt tttcttcgtt tgcacgagct ggtgataata
    28801 ctgtagaaag atcatcagac atttcctcgg ctgacttata acggtctgca ggttctttag
    28861 ccgttgcccg taaaatcacg ttttccagtg cttgtggcac atttggatca agtgctttta
    28921 tagatggaag atcatcttga aaatgtttta aagcaattgt tacagcagat tcaccatcaa
    28981 acggtacgct acccgtcaac atctcataaa ggatgatccc taaagcataa atatctgact
    29041 gcttcgttgc catacttcct ctggcctgct caggggacag ataatgaaca gatcctagca
    29101 tcgtattcgt ctgcgtgatc gatgtttcag ataaagcgat agcaatcccg aaatccgtga
    29161 tttttacaac accttcatta tcgatcagta cgttttgggg tttcaaatct cggtggatga
    29221 tttgatggtt atgagctaaa gaaatagcag aaaggatctg ctgcataata tttactgctg
    29281 tttcataagg aacaggataa tgtgtttgga tatatcgttt caagtccatt cctttgacgt
    29341 attccatcac cagatactgc atgttgtctt cttcaccaac atcgtaaaca ctaacaatgt
    29401 ttggatgaac gagttctgtt gctgctaaag cttctctctg aaatcgtcga atcgcagtct
    29461 ggtcattttg aaagtcaaat cgtaagactt taactgctac atcacgatcc aagattaaat
    29521 cgtgcgccaa aaatacattt gccataccac cgctaccgat atttccagtg atttgataac
    29581 ggccatttaa ttttttgccc aactcgatca tacactgtcc tccttatatt cgataagaag
    29641 aacggtgata ttatccgctc cgcctgcttc attggcacga tcaatcagct cagttacttt
    29701 atgagacaat gggccttctt gattgatgat cgttcctatt tcttcttcag acagcatgtt
    29761 cgtcaagcca tctgaacata acagcagtcg atcttttagt tgccaaagat gagtagaaac
    29821 atctacttcg actgttccag gcatgccgac agaacgtgtt aaaatatttt tccttggatg
    29881 gttcactgcc atttcttcgc tgatttctcc tgatttgact agttcattga ctaaagaatg
    29941 atcctccgtc aattgcatga ttttatcttc acgaatcaaa taagctctgc tatccccaac
    30001 attggcaatc gtgaaccagt catctgacag agcggccgct acgattgttg ttcccatacc
    30061 gttatattcc ggctgttctt gtccacgctg ataaatcagc atattttctt cttgaatcga
    30121 ttgaatgaac cattgggcga ttttttcatc gtcaacagct tcttgttttt cccaagcttc
    30181 gcctagattc gttaccgcca tctgactggc aatgtctccg gcacgatgac cacccatccc
    30241 gtctgctaat acagcaagct tgagacctga acggctggta aatacactgg catagtcttg
    30301 atttgtgtta cgtcgtcttc ctacatctga ttgatattca atctgcattt tttcacctca
    30361 ttactttttg cgcaaacaac aaatgaaaaa tccatctgtg taaaactgat gcggatacaa
    30421 agtcaacatt ttctcttcga ttgatgattg tagcatagga ttggtcaaaa catcaatcct
    30481 ctcaaaatca gggtgtcttt ccaagaaagc agaaacaacg tcttggtttt cttcttttaa
    30541 gatcgtacaa gtgctataag tcagaatacc ggaagacttt aaagttggtg cgcagctttc
    30601 taaaatttcc aattggattt ttggtaaatt cgctaattca tccggctgtt ttttataacg
    30661 aatatctggt tttcgccgaa gcagcccaag acctgaacaa ggcgcgtcta ctaaaatccg
    30721 atcaaactgc tctgcttcga actgtttact gacttctcta gcatccatct tttgagcgta
    30781 gacagcagaa gagacaccta gacgtgctgc attatcttca atgagtttga ctttgtgttc
    30841 gtgtacatct aaagcgacca cttctccacc gcatgacgga tctaaaaaag aagcaatatg
    30901 cgtcgtctta cctccgggtg ctgcacaggc atctaagaca tgatgttcag gctcgatttg
    30961 catagacggc gctacaagca tcgaactttc atcttggatc gtcatgacgc catcgtggaa
    31021 caatgagcta gaagctaaat gccctttttt cgctactata ccgtatggac tgacttggct
    31081 tttttcagct gtgatctctt cttcttgcaa aacagtgatg gcctgatctc tggaaagtcg
    31141 gcgtgtatct actcgggcac tagcatggct aggctgatat agcgataaac cgagcttttc
    31201 agtttcttcg tatccgattt gatccaccag tcgtttcgtc atccatagag gcaggctgat
    31261 tttgacagaa agtctttcga taggatcagc aatgccttgc agatctggtg ctccttgacg
    31321 ctgataattc ctcaagacac catttacaaa tttccctgtc ccaggatttc cttttacttt
    31381 tgcgatttcg accgcctcgt ttaaaatagc atgtgcaggg actttatcta aaaattctaa
    31441 ttggtataca gaaagataaa gaagcatctt gacccagtca tccacttttt ttgctttagc
    31501 gatcaatggt gcaacgtaaa attccaatag tcgctgatgg ctaatcgtac catagatcaa
    31561 ttctgtaaat aaacccacat ctttttgatt tagctcgctt tgtttgatca tctcattcaa
    31621 caaaagattc gagtaggcgc cacccttgtt cactcgctct aatgtcagta atgccatata
    31681 tcgtactgat tttttcattt ttttaggaat ttttttcatt atttcacctg ctgaccaatc
    31741 tgaacttgct gaccgcttcc gttaaggaaa tcatgtacgg cctgttttcc tttaccagct
    31801 ggctgtaatt cattgatggc taagacggtc tgtttaccgc aagcaatcca tagatttttt
    31861 ttgtctttcc ggatgatcgt accaggtgct ttgtctgtag tttctgccaa tacttcaacc
    31921 gataataatt tccagcgtat gccctcatag gtcgtgaatg caattggcca aggacgcatt
    31981 ccgcgtactt ggttgtcaat ttcttctgca gttttatgcc aatcgattgc ttcttgttcc
    32041 cgtgtgatgt ttggcgaaaa agttgcttct gactcgtctt gaggtactgg tttttgtcca
    32101 tccaaaatat tgggcaatgt ttctagcaat agctttcttc ctaaaaggct aagcttttca
    32161 aacatcgtcc ctacatcatc ttgtttagtg attggtatgc tttcttgcgc atagattccg
    32221 cctgcatcca tttttttgat catttccatg atcgttacac cagtttcttt ctccccattc
    32281 atgatggcat aatgaacagg cgcacctccc cgatatttag gaagtaaaga agcatggaca
    32341 ttgattgccc ctaattttgg tacttgcaat aacttttcag gcaagaattg gccaaatgcc
    32401 gcagtgacga tcacatcagg caccaattca atgatttctt ccatttctgg cgaaccggag
    32461 attttctctg gctgcagcac acggataccg tgcttcagag ccgctttttt taccggtgtc
    32521 ggcgtaatta ctcgtttccg cccaactgga cggtcgggct gtgttaccac tgcctggatc
    32581 tcgtaacctg attctatcag cccttcaaga atcggcacag aaaaagcagg tgtgcccata
    32641 aatactagct tagtcatcaa gatgttcctc catatattct tcaagttctt cttccgggat
    32701 ctgctgtatc attttctcaa tgaacaagat accgtctaag tgatcgattt catgctggaa
    32761 ggcacgggct aaatagccaa aagccgtcac ttctatctct tctccgtctc gatcataata
    32821 acgcacggtc acttcatctg ctcgcttgac cgttccatag acatgcggaa tactgagaca
    32881 accttctacg tcaaggcttt caccttttgc ttcgatgatt tctgggttaa tcagttcaaa
    32941 tttctcgcct tcatctactt cgatcacagc aattctcttg ttttgtccta cttgaggagc
    33001 agcgatccct attccgtcat tcgcaatcat tgtctcatat aaattgtcta ataaagcgat
    33061 tgtctcgtcc gtgattacat cgattggctg agcagttctt tttaatttat cattagggtg
    33121 gatcaatata ggatagcgca taatttggcc ctttcttaaa taaagtttaa tggttcgttg
    33181 tcaattgcca caaaaagacc ttgtcgctgt tctttctggc ttccattcaa aatttcatcc
    33241 aaaacatgag gaagattcgg ttcatgttta tatttgatga ttagttgata ataatatcgg
    33301 tttttcactc tcaaaatcat gctgggcgtt ggccctaata gcaagctttg agggcttaac
    33361 acttctttta gctgattggc aatctgaaag attttctttg ccgctacttg ttcttcagga
    33421 tggctggcgg ttattttcac agtaaagtaa taaggaggat agcctccacg atgccgtaca
    33481 tgcatttcct gctgataaaa ctgctcataa ttttgttttt tagccaattc tatggcgtaa
    33541 tgttgaggat tgaatgtttg gatcacgact tcgcctgctt tttccgctcg ccctgctcgt
    33601 cctgaaactt gggtaagcaa ttggaatgta tgctcactag aacgaaaatc cggtaaattc
    33661 agggaggtat cagcattcaa caccccaact aatgtcactt ctggaaagtc caaaccttta
    33721 gcaatcattt gtgtccctaa taatatatct gcttcttttg caccgaattt ttgtaaaatc
    33781 tgttcgtgtg ccccttttct tcgagtggta tctacatcca tacgcaaaat cctagcttgc
    33841 ggataaagtt ctcggagttc ctcttctact ttttgagtac ctgttccata gtagcggatt
    33901 ttattgccgc cacaattagg acagcgattg ggaataggtt cttcatgtcc gcaataatgg
    33961 cagcgcattg aacgtgtatc catatgcagt gtaagagaga tatcgcaatt aggacatgga
    34021 agaacaaatc cacagtccct acacatcaca aaagacgaat atcctcgacg attgagcagt
    34081 aggacagttt gttctttttt gtctaatcga ttttgtattt tttcctgcaa attagcagaa
    34141 aaagtagagg tccgatgatt ctgaaactct tcacgcatat ctacgatctc aatagctgga
    34201 agctgtgcag ctgctttggc tcggtggttt aactgcaata actgataaac gcctttttga
    34261 gctcgtgctc ttgattctaa agagggcgtc gcgcttccta gaactattgg gcaatgatga
    34321 tatttactgc gccaaattgc tagatctctc gcatgataac gcggtgtctc atcttgtttg
    34381 taacttgatt catgttcttc atcgataatg atcagcccga tatttttcag cggggcaaaa
    34441 atagcagatc gtgcgcctac tactacttgc gcttcttccc gctcaatctt gcgccattca
    34501 tcatattttt caccttggga aagtccgcta tgtaagaccg caactgattc tccgaagcgt
    34561 cctttgaatc gctcgaccat ttgcggagtc aatgcgattt caggcactaa cataatagcc
    34621 gttttatttt ctgacaaaac atcagcgatt gcctgaagat atacttctgt tttcccgctg
    34681 ccagtgattc cctccagcaa aaagacctga tctttttgct gctgacctgc tgtgatgatt
    34741 tgttcgacag catttttttg ttctgcattc agttccaatg ccgtcgtttg gtcaaatact
    34801 cggtctttat aagggtcgcg ataacgttct gattctataa actccagcca gcccttttct
    34861 tttccttgat tcaagacagc agtactgatt cctttatttt tgaaataagc aattggttct
    34921 tcttggctca gttcagataa acacaaaaga agttcttttt gtttcttggc attttgccgt
    34981 aattttgccc attcttcttc gatttgcttt tcagttaaca aagaacggac caaacgaatc
    35041 gtttttactt tatttcgtgt atggacttca tatttgatat ctactaattg ctcttggcgc
    35101 cagcgaatca attgagaaag gctgccttct tcttctgctt ccttccagga aatcacttct
    35161 cgctgatcaa acaatacctg aacttctggt gtgtctgcca aaggatagat caatttatca
    35221 tattctgctt tcatcacact cggaagcatc gtttgtagac aagtgatttt gaatgcgtaa
    35281 gtaatttttt tcatataatc agctaatgaa agtaattctt cattgaccac cggagcaagg
    35341 tctagcaaac gaataactgc cttcaaagat ggattagctg attcttctga tttttggata
    35401 gccataacaa atccttggac atgacgattg ccattaccaa aagggacttc tactcgcatc
    35461 ccgacttgca aagctgtttc catttcagag ggaaccaaat aagtgaatgg ctgatcggtc
    35521 tgcatagtag gtacgtccac aatgacttca gctgttaatg tcatggttcg tttcctcctt
    35581 tttttgtctt ttcttatcaa gcgacaaaaa gttccttgcc tattttacta gagatcgatg
    35641 gatttgtctt atcttctgcc aaatcctaac aaaaaattaa cagcagataa gaaaaaaaag
    35701 aactgtgtca aaaagttcag acacagcctt ttctaccaga caataagtgg cgaatgtttg
    35761 aaaaggaaac agctgggttt gcttttcttt ttagatgttc gctctatttt tctttattac
    35821 attttttgct cttcacggat acgtgattcc aattcgtgtt gttcacgctc tttttgtgct
    35881 tgacgttcct cttcttccat cttcaaacgt tcacgtttta attcaggatg tggatcattg
    35941 actacatttc ctgcatcgat ttcttctaaa gcttgaccga cgctttttac tgaatcaaaa
    36001 gaatctagag taggctgtgc acttgcatcc aattcatgcg cgcgtttact tgctaaaatc
    36061 actagagaat attttgaatt tacacgatct aatagtgagt caattgaagg ttttaacatc
    36121 ataagactac atctccttta acattttaat atatttaccg attacgcgat ctactcgaaa
    36181 atgttcactg gcaataatgt ttttgattcg ttcaactgct agcggcactt catcatttac
    36241 aacagcatag tcgtaaagag ccatcatttc gatttcttct tttgcaactt tcattcgttt
    36301 ttcgattact tcatctgcat ctgttcctcg gcctacgatc cgtgatttta attccgctaa
    36361 atctggcgga gtcaaaaaga tgaatacacc atcgggcact ttttctttga cttgttttgc
    36421 tccttggact tcaatctcca agaaaacatc ttttccttca tccaatgtct tgttgacata
    36481 tgacaaagga gttccataat aattcccgac atattctgcg tattccagca tctctccagc
    36541 ttcgatcatt gattcaaact cttctttgct tcggaagaaa taatcaacgc cttcgacctc
    36601 cccttcacgc attttacggg tagtcattga gatcgaatac tgaaaatcat tatcctcact
    36661 ctcaaaaatt gcttttcgta ctgtgccttt tcctacaccg gatggaccag acaacacgat
    36721 taataatcca cgctctgaca tgacgacgtc ctttcaacta gtctttttgt acttatcgtt
    36781 tattttgcac tttttttctg caactttcaa ggttatcttt aattatagct agaaattggt
    36841 aaaaaagcta ccctgtacca agaggtcgta aaaaagctgt cctgcatcaa gtaataagaa
    36901 cagccaaaca taaacagctt ctcatgtttt tcgtttggtt ggggttatta tcgcagatgc
    36961 aagcttttga acgccgtgta taagaggtcg tgaagaagcc gattagtttc gagtatgaag
    37021 aaaaattttg tgaaaatagt ttctcacatt tttgcataaa tttggcttaa taccgagaaa
    37081 atggtttttg aacatcactt attcaaaata aaaaaagatt gtgacacgaa ttttgtcaca
    37141 acctttaaat gtattcctag agcaaagaag ctaagcgaag aaatccaatt ctgtttattt
    37201 attgtatttc tttgttcagc atccttgcta aaagcccata ttggacaaag tattcactac
    37261 acccatgatc tcatcttttc gagaacgtgc tttttctgtc ggatcttcta cctcttctgt
    37321 gtcaattcga acaataaatt tccgattcat cgtcacgtaa gcaccgtcgt tgatcaaaat
    37381 aaacagttcg ttctcattat agtctgcaca ggcatctttc catacgtcaa agccgttttt
    37441 ttcagaaggg atatcccgtt taaccacagt ttttccactt aattcgtgga acgttacgtc
    37501 ataatatttc attatctcta cctctttcgt cattcaatat tttgtacttg ttctctgatt
    37561 ttttctaaga tcgtcttaga ctggacgact tgatttttaa tttcgattgc atttgatttg
    37621 gaaccgatcg tgttgatttc ccgattcatt tcttggatca ggaaatctaa ttcccgacct
    37681 acaggacatt gtgcttcgat aagttcatct agtttttgta catggatcgc cagacgatcc
    37741 agttcctcgt gaatatctcc gcgttccaac aagatggcta gctccgtcaa caaccgttgc
    37801 tcatcgactt tcgctccaag aaattcctcc agcttttttt gataccttat ttgaaattcc
    37861 ttttcataga tttctacaaa actatcgagt ttttttagta cttctttgaa ttcttcagta
    37921 ttctttttca acactaaagc taaagcttga ccttcttttt ctcgactcgc ctcaatagaa
    37981 tcaagtgcgc ttttcaatgt atctagagct aactgtgcca attcttccat gctctcttcc
    38041 ggtttttctt ctaccgttac gaagttttcg tccagcacga agcgttccgc catccgacta
    38101 attgacactt gattttgact accgtatcgt tgttgaattc cgtctgtcaa ttgagtgata
    38161 agtgaatcaa tcaattccca gttgatgacg atctgttttt cgtttttgcc aatataagct
    38221 agattcacaa atacttcgat tcgaccgcgg cttaactgct gtttaataag ctgacgaaaa
    38281 tcgttttcaa caaagttcag gattttagga cttcgtattt gaacatctag aaaacgctgg
    38341 ttgacacttt ttatttcaat atctaactga tacgcttttg tttcgcggat ggctttgcca
    38401 aaaccagtca tacttttcat tcgacagggt ccttcctcat tacatatttt ctattgcttt
    38461 ttgcagttgt tcaaactctt cgttcgtcaa tgtcaggcct ttccccattt tttcatggtc
    38521 tggcgcccaa tctcgaagat cgaattttgg cgggcgacca ttccagctga ctaggttcag
    38581 ttctttacgc caccccttgt tgttttctga caatatagcg atttcttcta cgatttcata
    38641 tgaaaattct tgtgccatgg ttgttcctcc ttgagataat ataaatatag gatcagtaat
    38701 gtgtcaactg gttgcttaag caattcatgc tgcaaacgat ccttgcgttt tccttgtagc
    38761 agataatcaa aataaacagt tttcgtgcgc tcattttgta ttttttgctg gtattttcga
    38821 taccttcgcc attcttcagt acttaattga ccaatttgtg ccaataaatc atccggcata
    38881 ctttttatat cttgttggca gatcatttga atcatcatgt ctacttgata gatttcattg
    38941 ggcagtaaaa aatgtttttt tgctaaaagt tctagcatcg ccaatccgca tgtctctggt
    39001 acgaccctgt tcttatataa attacgcagt ttttgccaaa attttatgct tttgaaaaaa
    39061 gataattcta actgaatttc ttttgttaag taagacaaaa atcctcgcca gtatgttctt
    39121 gcaggtttaa cagaatgaaa tgtataccag ttcccatagt aatagcctaa tcgttttttc
    39181 atttccagat agcctaattg taaatttaat tggttccttt ggctatcaaa aagcagaaag
    39241 ctgcctagtg tccacaatgt ttgacatttc caatggataa aaatgtctgg catacgaatt
    39301 tttttcgctg ggcctggccc ttgcacatct acgacaaatg cctctgttgc tcctttgtta
    39361 atcgcaatat caataggtat tttgttgcga tacccaccgt ctgcatattt attttttccg
    39421 atctttcgat aagccatagc gggataaaat gaagcagagg cgagtatcca atctggtatt
    39481 tcttctgttt ttgtctgttg gatatcagtc actacttccg ctagttctgg cagtttagta
    39541 gacaccgtat ataaacgtat tttgggatta tgtttgagta aggacaaatc caaattgtct
    39601 ttgaccatct tttccaatgg agcagaagaa accccgcctt caattagtgc tgttttcgtc
    39661 atttggcgtc tttctcgata gaagcgttca cgaaggtctt caactgcagc catttctggt
    39721 aacgcaagca cttgtcttgt cgacagcttt ttccataaat tcacagcttt tttcatatct
    39781 ccttgtaaaa tcaatgcgcc gttcaacgca cctaccgagg tacctgtgat aatctcaaag
    39841 ttgatatcat gttccttcag cgcctgccac acaccaatct gataagcacc gtgcgctcct
    39901 cctccaccta aaacaagtgc tgtatgatag accagctttt tatttaattg tgtggttcct
    39961 tgatagccgt ttttatgaaa aatacgcaac cattcttctg atagaggaga ttgaaataaa
    40021 aaacaacagt tttctttaat aaaaaaacga gcgcaagctt ccatataccg aaaaaatttt
    40081 ttccattcaa aagtttcacc ttcaatcaac agattattaa aaataacatc tcctctactt
    40141 ttagcaatag taaaatagac ggtatatttt ttcgatactg ctttaaaagc acattgcttt
    40201 tttgcagaac gccaaaaagc gtctctactt tcttgatgac tttgaaaaaa tggaaggggt
    40261 tgttttgctt gctggatagg cgaatacagc gacattttct gtgaaaagta aacttttttt
    40321 atctccatcg cgctctcctt tttcttcaag tataccagta cgtcataaaa aggtcatgag
    40381 tctcgtattc gactttgtag attccataag aaaacaattc ataaaacctc ctttaaataa
    40441 aaaaatacaa aaatcacaaa aattaattga aaatgagagt gttttcaatg aaaacgtgat
    40501 tttgtaatgg aattttaaaa taaaagaaac aagctttttt aatgcaaatg ttgtaaaata
    40561 aaagagatta agaggaaata agaggaggaa catgatgact gagtcagttt atgtacatat
    40621 tgataccaca agtaatgctg ttttaacaaa agggctgact gctactgact ttgcaaacag
    40681 tatcgtgcat tttcctcaaa acttgctctt gcttgatcca tctgcttctg ctggagaata
    40741 tgaatcccat acagggctga aagtaatccg tggtacagaa aatattcagc gtttcttttc
    40801 ctcttctcgt aacaggcgtg gattcgatga attgaagtgg atcgacttta ctgatttaac
    40861 gatgctgaaa gaattgacac ctttagaaat ttcagaatta ttatattttg gtcatatgaa
    40921 aacacatctt cattcgccgt ttttttataa actacagaat aattttgtat acttcgatct
    40981 taatgatcag ctgaatcgga tttattatcg ctatttagat gaattttata ggatttttgc
    41041 tagtaaatta agttcgatct tgtcagataa gatcaatgta aaaaaatctt ttttcaaaaa
    41101 agaaacacct gttgaaaaaa tcagtgtgga attattgaaa gaaatgcgta atttgatgca
    41161 ggaagggatc attttttctt ttgatcaagt tggtttgatc gatggtaaat atcgtatccc
    41221 aatctatgtg attgaagatt atatttggaa attaaaaggc acccggtatc gagaagagga
    41281 aatcatcgct actttaatct actctgtcac cgatcgacac tggcaattgg tagaagatgc
    41341 cgatctttct tatctgccat tgaagtagat ctatttctta tcaaaaaata aaaaggaaac
    41401 aagaaactag gacatgattc tgtctcaagt ttcttgcttc ttttttattt acagctcctg
    41461 tcgtttatct ggcacaaaaa tcgaaggagt cgtttgttgg atccctaata aaacgatgat
    41521 cgttacaata gctgtactca acccgctggc accattcatt acgaaagaaa agagccaagg
    41581 attcatcccc catagtgcat acgctcccca gaaaaccact cctgcaataa aatgccaaaa
    41641 atatctggaa agtgcgccaa tcaatgcacc aaacacgatg ctttttctaa tttgtttcgt
    41701 attatcgtct acatagcctt tttggacatt tgaagccatg agccctgctg cgcctgcaaa
    41761 agtataggca atcgggtact caatcaacac ttgaacgaca cttaaataat aaacttgtcc
    41821 caacggaaaa tgtaggatgc cccaaatgaa acctgccagc atccctgcct ttgtccctct
    41881 tcttaacgca aaaagagtca atggaatctg ccctaatgaa atagaaaaac tgctgccgat
    41941 ctggatcgga atcaacgaca acaccatcgc taacgctgca acaatcgttc cttctaccca
    42001 aactctattt tttcccataa aaaaacttcc tcctttgaat aaaaaagtca caaaggagga
    42061 agcagctttc gaaaatagtc aaacagctgt ttattcacaa ttcctacgct cgcataaccg
    42121 atacaggtac gaagggttta gaaatagatt caatctcagc ccaattggac tcccctttgt
    42181 gagtttattt attatttatt ttttgtttca aacaatggac taactggttt gttttcatgg
    42241 atacgtttga ttgcatctcc cattagtccg ccaacactta cttcatcgat tttgtcgatt
    42301 ttacgatctt ctggaagata gatcgagtct gtaacaacta gacgctcgat agctgaatct
    42361 tctattcttt gtaaagcagg gccggataat actggatgtg tacatgaagc atacacacta
    42421 gttgcaccag cttctttcaa agcattggca gccaatgtga tcgtacctgc tgtatcgatc
    42481 atatcatcga tcagtacaca agttttgcct ttgacttgtc caatgatatt cattacttct
    42541 gcaacatttg cttttggacg gcgtttgtct atgatcgcaa tcggagattt caaaaattcc
    42601 gctaatttac gtgcccgtgt gacaccacca tggtctggtg aaacaacgac aacatcatcg
    42661 cctttgattc ctttttctaa gaaataattg gcaataagtg gcgcacccat caaatgatcg
    42721 actggaatat caaagaaacc ttggatttgg actgcatgaa ggtccaaagt cagcattctt
    42781 gttgcaccag ctttttgaat catgtttgct actaatttcg ctgtgattgg ttcccgtgca
    42841 cgtgctttac ggtcttgacg cgcatagcca taataaggca tgactacgtt gattgttttt
    42901 gcacttgctc gtttcagtgc gtcaatcatg atcagcaact ccatcaagtt atcattgact
    42961 gggctgctcg ttgattgaat aacatagaca tgcgatccac gaatactttc ttcaatgttt
    43021 acttgaattt ctccatcact aaattgagta acagatgatt ttcctaactc gacgccgact
    43081 gctgctgcaa ttttctctgc taatgggcga ttggaattta acgcaaaaat ttttaatctt
    43141 gggtcaaagt aatgttttga catggggacc tccactttct ttttcacaac tctagaattc
    43201 tacctaataa atagtagtca tattttttaa ataaatcaag tgattttgca aaagtcttag
    43261 tttagataag ggagtttttt tgcatatcct tctttattga cttgtcttgc tctcgcaatt
    43321 gccagcgcat attctggaat attgtctgta attgttgacc cggcagcaat cgaactgttt
    43381 ttagctacct cgacaggtcc gatgatattc gtgctagaac caataaagct gtggtcgccg
    43441 acagtcgtat gatgtttgtt ctttccatca tagttgacga agacaacacc acatccgaca
    43501 ttgatttctt ctcccagcgt agcatcacca acataagtca agtgaccgac tttagttcct
    43561 ttgccgattt gagcattttt cacttccaca aagtttccga tatggacgtt ttcgccaatt
    43621 tcagcttttg gtcgtaaatg tgcataaggt cccacatctg catgtttctt gacatggctg
    43681 ctttcaatga ctgagttttc aatgacgacg tgatcctcaa tcctactgtc tacgattttt
    43741 gaatgtgacc cgatgacaca atcagaacca atgactgtat ttccttggat ttgtacacct
    43801 gcttcgatca atgtgtctgg accgatttct acgcctgcat cgatgtatgt cgttgctgaa
    43861 tcgacaaagc ttacgccatt gaccatatgc atctggttaa ttcgctttct catgatctca
    43921 tttgctttag ctaacgcgat ccgatcattg actcccattg attcttcaaa atcatccgtt
    43981 tgataagcag caactgtatg gccttcttct tttaagattt cgatgatatc tgttagatag
    44041 tattcacctt gagcattgtt tgttccaact ttgcttaacg catcgaacaa agcttcgttg
    44101 tcaaaacagt aagttcctgt attgatttct tgtacaagag cttcttctgg tgttgcatct
    44161 ttttgttcca cgattttttc tacgatccca atatggtcac ggatgattcg tccatatcct
    44221 gttgggtttt ctgcttgtgc cgtcaagatc gttgcacttg cattttttcc ttggtgatat
    44281 tcaaaaagat tgttcagcgt ttcagtagtc aataatggtg tatcgccact gataactaac
    44341 gttgttcctt tttttccttc caagaaagaa gcagcttgca aaacagcatg tcctgttccc
    44401 aattgttctg cttgtaacgc atatttactg cgttctccta gttgtgcttt aacttgttct
    44461 gctccgtgtc caacgatcgt aatcacttca tctggtttcg tttcactgac ccgattaatg
    44521 atatgttcta ccataggttt accagaaacg ggatgtaaaa ctttatataa ttttgacttc
    44581 atgcgggtac ctttccctgc cgccaaaata attgcataac gtgcgtccaa ctgcgtcact
    44641 cctaaatata gtttgctgat ttcagtttat cccagtatac ccattttttc aacaaaacaa
    44701 gtgattttct tttatcccag cgttttctgg ataaaaaaat agatagacca taacgggcct
    44761 atctatttgg taaccggtgc tctcctgcca actcctcggt cacaagtcac actactcata
    44821 aaacatgaaa agctgttttt tgaaatcgtt tcttgtgact tagagttaaa cggtaggctt
    44881 acaacctctt cattaaacgt ttttcaatca gctgaccttc ggtattagct caataaacgg
    44941 caaaatatga ggagcaattt ttccgtttat tgagctaata ctcaggacag gacgctgatt
    45001 tcacaacctc tagataaacg gtgttcaaaa gccagtttct cggtattaag ccaaatttat
    45061 gaaaaaatgt ggaaagccat tttcacaaaa tttttcttac tactcgaaac taagcggctt
    45121 tttcacaacc tcttattctg aaaaataatt tcctggcaca accgtaatat ttttcgtttg
    45181 agtatctaca tctttgacat aaagcagtga cgtataatca tcgatggcgc gatgaccgtt
    45241 gaattttgat tcggcaaata cagtgatgcc aacaagttct gattcgaatt cttcaatcaa
    45301 gctcttcatt ccgttgactg ttccgccgcc tttcatgaaa tcatccacta caaggacacg
    45361 tgaaccacgt ttcaaacttc tcttagacag ttccatcttt tcaattcttt cagaagatcc
    45421 agacacatag ttgacactta ctgttgatcc ttctgttatt tttgagtccc ggcgtacaat
    45481 aacgaatggc gcattcagat aataggacac agcttgggca ataggtacgc cttttgtggc
    45541 tacagtcatt acagcatcga ttttttcacc aaggtattta gaagcaatga ttcttccaac
    45601 ttgacgcagc agttcaggtt ctcctaacaa atcagagaga taaacatatc ctcctggaag
    45661 cagacggtct tgttctgata gacgttctgc tagagattca atatattttt tcgcctcttc
    45721 atatgaaatt tcagggatga acaatacacc acctgcagca cccgggattg tttccaaggt
    45781 tccataccct cgttctttaa atgttttctt gatgattccc aaatcttcac tgatagaaga
    45841 tttagcagat tcataacgtt cggcaaagct tgttaaggaa atcaattcat gcgggtgatt
    45901 caataaatac tgtgtcatgt caactagacg ttcactgcga cgtactttca cctattccaa
    45961 ctccttttaa gaaattttat cgttttacat tatataagtt tttcttcaaa aattcgagca
    46021 ttttatgaaa aaataagaaa atagttcggt atttattaaa ataaaaagaa gcctataaaa
    46081 aatttttcgt ttttataagg cttcttttct ttataattta gttatttttt cttctgaagg
    46141 caaccaatat tcgtttgatg atatttacaa tcaggaacaa agcaataaag actaatgtga
    46201 ttgttgctcc tggaggtgta tctagataaa acgagctagt tagtcctgac agcatcccta
    46261 gaaatcctac acaaacactg atagcaatca cgacattgaa gcttttgcct aatcgcatac
    46321 cgattgctgc gggaagaacc atgattgcgg atatcaaaag tgcaccggca atcgggatca
    46381 tcacagcaat agccacacca gtaatcacat tgaacatcat cgacatcaaa tgaacgggta
    46441 gcccatccac gtgggcggta tcttcatcaa aagtcagaac atacatcggc cgtttgaata
    46501 aaaagaacaa tataccgatg gcaacgaata agattcctaa aaagatgact tgctcccatg
    46561 taatggtcac gatcgaacca aacagatagg attggatact tgttgctgaa ttccctccgc
    46621 tcaaattcat caatactaac gctagcgcca aaccaccagc cattaaaatg gcaatggaga
    46681 tttctgaata ggttcggtag atcgttcgca gatactccaa tatcacagct gctaatacaa
    46741 cgactagcat ggtcgtaagt gtaggattaa ggttcaaaaa gaatcctaac gctacccctg
    46801 ctaaagagac atgagaaagc gtatcagcca tcagcgattg tcttctgatc actaaaaaca
    46861 cacctagcat cggggcgatt ccggcaatga agatagcggc aagaaacgct cttctcatga
    46921 attcatatga aagcaacgcc attgagaatc ctcctttctc accagtcgga tctgtctgtc
    46981 cgcatactgt ttgatatctt catgatcatg ggtgatcatt agaactgatt tcccatggac
    47041 atgcgcacta tgtcggagaa gacgataaaa ttcatttctg gattcttcat ccatacctgt
    47101 tgttggttca tcaagaacaa ataagtcagg gtcagtagca aaaatacgcg ctaaactgat
    47161 tcgctgcttt tgtccgccag acaattcacc tattcgccga tttcgcatat cccacatccc
    47221 tacagcttct aaagcacgct gtacatgttg atgatctttt tcagagagac gcttgaacca
    47281 gcggcctctt ggatatcttc ctgaacggac taattcgatc accgtactag gaaaacctgc
    47341 attgaaagat gcaacttgtt gaggaatata accgatactt aatttttttc cttcttgatt
    47401 tttctcagca atctttatca ttccttttga aggtttcagt aatcctaacg atgctttcac
    47461 caaggttgac ttggctgctc cattttctcc agttaaaatg acaaattcac ccgcatctac
    47521 atgataagag acatcttcta gtacaggttc atcatcatag taaaaggtca aatcagatat
    47581 ttcgatataa cgcaccttac aacctccatt ctaaaactta attgatactt tcttttaaag
    47641 ctttcagatt tttttccatg acagaaatat aattttcgcc tgctttgatt tgttcattag
    47701 tcaagctttc taaaggattc aacacttcta gcttcactcc tgtttcattc gacaatgtct
    47761 cagctacctt cgaagaggca ttttcttcaa aataaatcac tttgatgttg tttttcttca
    47821 caaattcttt tagctcagct aagcgacttg gtgtgggttc ctgatctggt gaaacgcccg
    47881 aaatcgctac ttgttttaag tcgtattgat tcgctaaata agcaaaagca gcatgctgag
    47941 tgacaaatgt gcggtttgtt gcatctttta gctcatcgga gtatttttga tccagtgctt
    48001 caagcttttt gatataagca tcggcattct tcgtaaaagt ttccttttta tctggatatt
    48061 tttcgcctaa ttcttcagca atcgttctga cttcttttat agctaatacc ggatcgagcc
    48121 aaacatgtgg atcgtattca tgtgaatgac catgcccttc ttctgattct tcatgttcgt
    48181 ctgcttcttg cgattctaaa cggtcgattc ctttagctgc ttcgatcatc aaggtctgtt
    48241 tgctatccac tgaatccttt aacgaatcca caaaaaattc catgtctgaa ctattataca
    48301 cgaaaacatc tgcatcggaa atttctgctc tttcttttgc acttggttcg aaatcatgcg
    48361 gctccgttcc agcagggatc aaaagtttca cgtttccttc atcccctacg atctcttttg
    48421 taaaatcata catcggataa aaagtcgtaa cgatcgtcaa atcctctttt ttgtctgctt
    48481 ccttgttcgt atttccacat gctgcaaaca gtaaagcacc tatcattacc gtagctgtca
    48541 aaagatattt tttcatttat atgctccttt caatgaacaa atcgtaattt tacgatttat
    48601 taacgtgaac taatgtatca aaataaaaaa acacagtcaa tagaaatcca tcaatttctg
    48661 atttaagcat gtatattctt gattaaatcg taaaatggat gagttgctgc tcatatctag
    48721 ccatttcact acaataaaaa actgaagaat accattttag gattcctcag tttttcatca
    48781 cctattttac ttcttatatt ttattgcagg gttcgtacta aataaacttc ctcacaaaaa
    48841 ccttttaacc cattatatac tctctgcgct cttgaataat gttgacacaa ggcaaaaacg
    48901 gttggtccgc ttccactcat caatgcagca tctgctccgt acttgatcat acgctctttg
    48961 atttgatgga tgactggatg ccgctttccc gttatatctt ctaaactgtt tcccattttt
    49021 ttgatcatct gctgataatc ttgctctcgg atggcttcag caagtccgtg gatgtcttga
    49081 tgttggatgg cttgcgtatc tacttctcta aacactgtac gtgtagagac actcattctt
    49141 ggtttgacca acacaaccca gcactgtggc atagaaggta atacttggat ttcttcccct
    49201 ttgccaccga caaatgccgt acttccgtag acacagtaag gaacatctgt accgacttcc
    49261 aaaccgattt ctgccagttc ttctaacgaa cagcccagat tccataattg gttgatccct
    49321 cttagagcag ctgcacagtc tgtacttcct ccgcctaatc cagctgctac tggaatattc
    49381 ttcttaacaa agatcttgac accggttttg atattgtatt tattttttag caataaagca
    49441 gcttgataaa cattgttccg ttcatctacc ggtaaaaatg ctttatttgt ttctacaatg
    49501 attttgtctt ctgttatttc ttcaaaaaat agatgatctg ccaagtctac gctcgacatc
    49561 accatttcca actcatgata cccatcttgc cgtctatata atacatccag tcctaaattt
    49621 atcttggctg gcgctttttc aatcaattcc atcctctcac ccattcgaaa agtctaagtc
    49681 gcaagtattc tatcataggg aaaaataaaa gtatagctta tgtctgccta gtggttgatt
    49741 ttgtcatcgt ttcaacagct ttcacagaat tttctcttca taatccaaac aagttctagt
    49801 gattcttata attctgtgag cacttcttct gccaaactcg gaacatttcc tttttctttt
    49861 cctatcagac tgagtagctg catggtagca aatccgaaat tacttccttt cctataagca
    49921 aaataacgtc cttcccaatg atcgacatat tttaatttct tttcataagc agactggaag
    49981 gaatagaaaa aattaccata attatatacg atatgcatga ctttttcttg aaagaaagaa
    50041 aaatctgttt ctccaacatt agctaatgga gctaagccta gattggcttc cgagtagccc
    50101 attttctcgt atacaataaa cagattggct aacagatagt cagctaattc ctcagattct
    50161 ttaggtaaga cccgcaacaa atcatatccc gcctgcttct tcgtcatcgg ctgagcggtg
    50221 atgaagccaa cgactttttg atctttacgg acaataccga caccgctaga taatacatat
    50281 gatttatcaa atcgtcccac agagaagtat ttttctcgtg caccttgaag ccatttttgt
    50341 gaaacttcat ttacagcttg atgtaattct tccggcagtt gatcgtacca agtaaaatgg
    50401 tatccttctt tcatcaaacg ttgatattca agttgctgac tcagccgaga caagtcttct
    50461 gttgctagat caacaatccc tgcttcacct actttcgtga agtgaaaacc caattcatga
    50521 agcatcacta cgtagctttc tgatatctta taaaacgcaa gctgatagcc taaacaatct
    50581 gcttgtttca taaactgatt cgttgctgcc cgcatcattt taggattgcc aactggatct
    50641 cctaaaacaa agcatttgtt tcctttgatc tgataaccaa aaacgacttg atcttggtcg
    50701 tcttcttggt aataaaaata actgtaacct gacaagcgaa gctgatggct tgtagctgtg
    50761 cctccgtatg tttccaataa acggtcaaaa cggtcttttt cgtactcact gccaagcttc
    50821 gtagtatctt cagctaaata ttgataaagc gccactaaag ctagcaatga gatgcccaaa
    50881 ccaataagcc ctgagaacca cacatcatct gaaggaaaca aaataaaatg atttcctgtt
    50941 attcgaccga ctaaaaagcg tccgctgtga tagcctgcaa ttgcgtaaac gataaacaaa
    51001 aagccgaaca agctagcatc aaagattata gctccccaag aataaacgaa ttttgttcga
    51061 taaaattctt ttctggataa ccacacagct aacagaatca agacatatac caatatcaac
    51121 tgccaagata acgtacgtgt gattgtattt aaaataccaa aagatagtaa agcaatcgta
    51181 ggcagaaatg cctttttgac ttttactgaa agtgctctag caaggccgag taataaaaag
    51241 ccaaccaata gattcactgt ctgatctaaa aaattgaatg agaacggcaa taatacttga
    51301 aatagccgac tgattgcaga cagattagtg attgttgata gaagtaccat catgatcccc
    51361 gcaaaataga cagcacttac gagcacgata tgcgcaacct tttggaaaaa cagtcgcgga
    51421 atgttatcta aaaatcgatt gattttgact cctgtatgtg tgatgaacaa tagaagtccc
    51481 gtcataaaag gtagaacata ataaaacaac cgataatata atagccaaac tactgctaca
    51541 tcttgccgaa cagacaattg actcattcct aagatcatca aaacgtcaaa agtccccatt
    51601 ccacctggga ccatcgtcag cattcctatc aatgtagcaa tcatgaacat aggatagatc
    51661 gaaagcatcg aaatatctat tctcatcaac ttgccgatga tcaaaaatac cgcaagggct
    51721 cccgtccatt gtccaaagga tgccagtagc agaccaagca agccttttgg ataaaactcg
    51781 aagaacaatg tctttctctt tagataagca aaaaagaaaa tgactggtgc taaaaaacta
    51841 ccgccgaaaa gccagatcca atagcttcga aaaatacttt ctgactgaat aaaaaagaca
    51901 tcaataaatg taagaaacga ccatacagac aaaccagtca gcataaatag tgcgactttt
    51961 gatacagtgg ctaaaaccat ttttctattt gtctgctttc cataaaaact agcccgcaga
    52021 cttgctccta ccacaccacc aaaaccggcg agattgttga tcgtgtttgt tacccacgca
    52081 gcaagaagaa actcttttct ttccattttt ggttttcctt gtttttctaa gactctgatc
    52141 gtcacccaat catacaacaa catcggagtg acacccagca gtccagccag aatcatgagc
    52201 aggatcgtca tgcggctttg ttgtcccatc ctttgccaaa tatcttgcca actcatgcca
    52261 ttagcaatat ttgcgacttg atttgccaca aagactaaca cggagccgaa aaaaatcagt
    52321 tttaaaatca gactatgttc ctttatccat tgcagcatca agtatcgttt atttttcaca
    52381 ttttcccatt cctaacttgt atacttttgt gtcatacccc aatgttatct tatttatttt
    52441 aatttttcca ctttagacct gttctttgct tgcgatgata gaaaaagaaa gatatcctaa
    52501 tgctaaagga gaggataaca tgaaagtagg atttatcggc acagggaata tggcacaagc
    52561 tattattgat ggtttattaa aaaaaggaac agtctcgaaa gaagaggtgt tcgtttccag
    52621 tggacatttt gaaaatgcac aaaaatttgc tgctgaaact ggcgtccatg catgcaaaag
    52681 taatcaggaa gttgcatcac aatcagatat cgttctttta gccgtgaaac caaaaatcat
    52741 tgaaaaagta ttggaagaac taagagaata tagccagaaa gtcttattca tttctattgc
    52801 ttcaggaaaa tcattaatag atttagaaac agcgcttgaa gatcctcagg cctccatcgt
    52861 acgtgtgatg ccgaatgtca atgtcagcgt aggagcaggc gtttctgcga tttgcaaaaa
    52921 tgaagctgcc acggaggaac agcttcagca agctacgatg atttttgaag caatcggcag
    52981 cgtctatcct ttagcagaat cagatttcag tacattcatt ggccttgctg gcagctcacc
    53041 cgcattcgtt tacatgctga tcgatgcgat gggacggact ggtgtactga atggtttgtc
    53101 caaacagaca gccactgaga ttgctgcaaa agcaattatg ggttcttgtc aaaaattcct
    53161 ttcaagtgat aaaaatccat gggaacttgt agaccaagtt tcttctcctg gcggtacaac
    53221 tgttgcaggt gtagttgcct tagaagaagc aggattcatc ccagcaatca tcaaaggaat
    53281 caatacgacg atcgagaaag atcttgagat gttgaataaa aaataatgat agcaatgttt
    53341 tttcgtgcct tacaaaaaaa gaagagctgt ggcttttgcc gcggctcttc ttttgtattt
    53401 tttattattt agcataatca gttgcacgag tttcccgaat aacgattact ttgatgtgtc
    53461 caggataatc cagttcttct tcgattcgtt tacgaatatc acgtactaaa cgaacagcgt
    53521 ctaaatccga gatttcttct ggcttgacca ttacccgaac ttcgcgtcca gcttgaactg
    53581 cgtaacttga ttctacaccg gcgaagctgt tcgaaatatt ttccagactt cttaaacgac
    53641 ggatgtagtt ttctaatgat tcacttcgcg caccaggtct tgctgctgag agcgcatctg
    53701 ctgcagctac aaggacagag ataacagaag tagcttccac atctccatga tgagaagcga
    53761 tcgcgttgat tactactggg ttttctttgt acttggcagc taattccgca ccgatctcaa
    53821 cgtgagatcc ttcaatctca tggtcaagtg ctttcccaat atcatggagc aacccggcac
    53881 gttttgctaa ttggatatct tcgccaagct ctgctgctaa gataccagct aattttgcaa
    53941 cctcgaccga atgcttcaag acgttttgtc cataactagt tctgaatcgc agacgtccga
    54001 tgatcttgat tagatctgga tgaagtgtat gagcaccgac ttcaaacgct gcctcttccc
    54061 cgtattcgcg aatacgttca tccatttctt tacgagattt ctcgaccatt tcttcgatac
    54121 gcgctggatg gattcgtcca tcttgtatca gtttttccaa ggtcatccgt gcgatttctc
    54181 ttcggattgg atcgaatccg gaaagaacaa ctgcttccgg tgtatcatcg atgattaaat
    54241 cgataccagt cagcgtctca agcgttcgaa tattacgacc ttctcgtcca atgatacgac
    54301 ctttcatttc atcattcgga agggtaacga ctgaaacagt cgtttctgaa acttgatctg
    54361 ctgcgcagcg ttgaatcgct aatgataata agtttttcgc tttgcgatct gcttcttctt
    54421 tggcacgctg ttcagattct tttaccatta gagttaactc atgattcagc tcttcttcag
    54481 tcgatttcat gatgacatct cgtgcgtcct cttttgataa accagcaatt ttttctagtt
    54541 ctttttgttg atcttcaatc attttttcaa cgtctttttc tcgctcttca attaattgct
    54601 gttttgaact aagtgcttct tctttacttt caagtgagtt ctcgcgtttt tctaacgagt
    54661 catctttacg attcagcgtt tgttcgcgtt gaatcaaacg attctcttga gattttaatt
    54721 ctaacttact ttctctcagc tcactttcaa cttcagaacg gtatttctga ttttcttcct
    54781 tagcttctaa caatgcttct ttttttagag tttctgcttc tttttttgca ctatcgatga
    54841 ttccagcagc tgatgattgt gcaccagcta tttctttctc gtgacgtgac tttgcgacca
    54901 taaaccctaa accaagaccg acaattaaac cgatgatagc gaggagaatg ttgaatacca
    54961 taaaatccac ctccatacta tctttttcat ttttatcatc tatacagctt ctatgataaa
    55021 ttattctaaa ctcgtcaata tgcatcttcg catatatgtg tacaaaaaac atgcacaact
    55081 ttattctaat gtttgtaccc cgtagtgtca actttaaata aacaaagaaa cggctttcta
    55141 cttattcatt aaacgatggt ttttaaaata aatgacacta gtttcatata ggtaaacctt
    55201 taaattgaga aacttttcta ttaaattatt ctttgtagat gaacagatat ttttatttta
    55261 tgtacccact cgtataatta aataactcac gatttcttta ttcaataaaa aaacggcagg
    55321 tcaaggagag tacctactct tcagaccagc cgtttttgtt tatcataatt tttattcttc
    55381 tactaaaggc aattcttctt gtcctttttc atcttctggg acagcgactt cttcaccaat
    55441 accataagct gctctaacta gagcagaaac ttctgccatc atttcaggat gattagccat
    55501 atagatttta gcgttttccc gtccttgacc aatccgatct tctttataag aataccaagc
    55561 accgctttta tcaacaatgt ctttttctac tgccatgtct agaagttctc cttcttgtga
    55621 gatccctaaa ccatacatga catctacttc agcgattttg aaaggaggtg ctactttgtt
    55681 ttttacgact ttgatctttg tacggttacc aacaatatct gtaccttgtt tcaattgttc
    55741 tgcacgacgt acttccaaac ggatcgttgc gtagaatttc aatgcgcgtc ctccaggagt
    55801 gatttctgga ttcccaaaca tcacgcctac tttttcacgg atttggttga tgaaaatagc
    55861 gattgttttt gttttgttga tcgaaccaga gagtttacgc aatgcttgag acatcaaacg
    55921 tgcttgtaac ccgacatgtg agtcacccat ttcgccgtcg atttctgctc gtggaactaa
    55981 agcagcaact gaatcgacta ctacgatatc tacagcccca cttgatacta aagcatcagc
    56041 gatctctaga ccttgttctc ctgtgtcagg ctgtgaaaga agtagttcat cgatattcac
    56101 acctaatttt tgtgcatatt gcggatctaa cgcatgctca gcatcaatga aagcggccgt
    56161 tccgccattt ttttgtactt ctgcaatagc gtgtagtgca actgttgttt tacctgaact
    56221 ttcaggtcca tatacttcga tgatacgtcc acgggggtaa ccgccgacac ctaaagcgac
    56281 atctaacgca agagagccac ttggaattgt agagatttgt tggtcgattt tttcgcccaa
    56341 tttcataata gagcctttac catagctctt ttcaattttt ttcagtgcag catctaaggc
    56401 tgctttacga tcatctgcca atacgataat cctccttata tttacaaatc agagcaacat
    56461 ttcattatcc ttatcatatc ttttttagtg aaaaaaagca agaaaaaacc gaacaaatat
    56521 tcgcatttat cattttctta aaagctgttt tctcaaaaga tcaaatcctt gcataaccgc
    56581 attatatctg atagcagcac gatctctggc aaagtgatat ttttccgaaa ccacgccgtc
    56641 tttagatgaa atagcgatcc atactgttcc tgcagattga ccttctaacg tgtccggtcc
    56701 agccactccg gtgaaagcta cactgtaatc tgttcttgct atctcacgtg cttgaatggc
    56761 catctgctcc acacattctt tgctgactgt tccatattct gctaatagct ccggatcaat
    56821 ctccagaaaa ccagcttttg tttggagcga gtaggtaacg aatccgcctg gaaatacttc
    56881 agatacacca gcaatgtcgc ctaatgcggc ttggaaggcg ccggctgtca aactttccgc
    56941 tgctgttaca gtctgcttgt tttctttcag tagttccact acgacttttg ctagcgaatt
    57001 atcatcgccg tatccataaa aatattcccc tactcgttct tggatttttt cttctaatgc
    57061 taaaagagct tgattccctg cctgaacatc atttgttttc actgtcagtc gtaatgtcac
    57121 ttcatttggt ttggcatatg gtgcgatcgt tggattgatc tgtgtctcaa tcagatcttt
    57181 tagctcagtg accagtcgcg attcaccaat cccataaaag cgcaaaactt tagaaattag
    57241 tttttcttca gaaggaaaac gttcctctag taaaggacgt acttgttcca caaacattgg
    57301 tttcaactca ttaggcggac cgggaagaag gatatacgca tgtgtatctg tttgataaaa
    57361 agtccctaaa gcaagccctg tacgatttgg tagaggaacc ccgccttcga taatctggga
    57421 ctgttgcaga ttgtttttgg tcatttttcg atgggttgtt tcaaaatatg ccaataattt
    57481 tttgtatcct tccgtatttt gtatgagaga cttaccgagg tgagccgcag ttgcttcttt
    57541 tgtcaggtca tcttctgtcg gtcccaatcc gccacataag agtatgagtt cacttcttgt
    57601 ttcagctaga gcaatcaact cttctaaacg ctgctgatta tctcctacaa ctgtttgata
    57661 ataaacttcg atacctagat cagctagctg ttctgacaag aaagtggcat tcgtattcac
    57721 gacttgtcct agtaaaagtt ctgttccgac agctattatt tctgctttca ttacttcccg
    57781 ctcccttata tagtatacgc tgtattttta tattttttta tttaaaaaga gggcaaggag
    57841 ctgtgacaaa aatcttgtca cagctccttg ttccaaataa acagtgttct cctgccaaaa
    57901 cctcggtcat aagtcacaat atacataaaa catgaaaagc tgttttttga aattatccct
    57961 tgtgactcag agttagacgg caggctcaca acctctccac taaacgatac ttacattgat
    58021 cctttgaaca caccgctgtt tttgatgaag taatccacac ctgaatagat agtaaagatc
    58081 agacaagcat aaagcatgat ttgatctact ggaataccga tcaggctgaa tgggatatta
    58141 ttgataaaca gcaagataat agcaaccatt tgtgtagccg tcttgacttt tcccggccaa
    58201 gctgcagcca tgacttctcc atgttcgaca agtagtaaac gcaagcctgt gacggctaat
    58261 tcacgacaga caatgatcgc tactacccaa ccaggggcct ttccttggtc aaccaacatg
    58321 ataaaagcag tcataactag cattttatct gccaacgggt ccgcaaactt gccaaaatta
    58381 gtgacaaggc ctcgcgcacg ggcaattttt ccatctaacc agtctgtgat actagctaaa
    58441 gcaaaaataa ctgcacctac tagctgtgtg acagccagtg tggtgtctcc tacgttaaat
    58501 tgtccccaat ctaaaggtaa acctacaacc aaaatgaaaa tcgggatcat acaaattcta
    58561 agtacagtta atttatttgg taaattcaca ctatcgactc ctttcttccc tattctacgt
    58621 gactatcagc gaagtttcca ccgatattat ttacttttcc aaatgaattt attcaaagga
    58681 gtatttttat tgaaattgat ctttttgaat taacgaagaa ggaccgcgac acagatttgt
    58741 cacgatcctt cttttttata cctacaagta aacagatgcg taaactaatt tatacgatca
    58801 ttctgcgtat tgaagagtaa ggttcacatt ttttggactc tgattgtttt cccctggatt
    58861 aactggtacg gattctccat tcgctttgat cgttgcattg cttgctgcac caatcgtgat
    58921 ggtcgcattt gttgctgttt ccggtaacac ggtactctgt gtttcatttg ctgccagtgt
    58981 cccttgataa acataggcat tgtctactag cacacctaac catacacgat tgacagcagt
    59041 aaattcaagg gttacaggct tggtagcgtc tgtgatattt actgcgatgg cactgccaga
    59101 atcttctcct gtagctattg ccattttctt ttcttcactt gattttgttg ttgattctac
    59161 tgtagaagac tctttggtct gcgtgctttg ctctgaggaa gaggactcct cgactgatcc
    59221 ttctacttta agcgaagaag ctgtgtctcc gattattgga tcagcttgac gatcttgcca
    59281 agtcatatag cccacgacaa cgacaatcgc caaagcaacc aatcctaata aaatgacagg
    59341 aagacttgtc caaaagcgac ttggatgcga ttcttcctga tgcattgctt ttctagaagt
    59401 acttactgtt tcaggctgcg gacgttcagg gaccgatcct gtcaatttgc ttttcccatc
    59461 aaaaacatcg actaaatggt ctccatcttc tcctacagct tcagcgtatt gccgaataaa
    59521 tgcccgcacg taaaatttac caggcaattg gtcaaaatca tcattgtcga ttgcttccaa
    59581 ataacgtttt tgaatttttg taatctgctg taattcatct aaagatattt ttttattcag
    59641 gcgtgcttgc cgtaattttt ctccgatggt ttcaaaagcc actcgttcat cttctccagt
    59701 ctgtttgatt ctccgaagca tctgctgttg caacgaaaga cgttatgttt gggtgctgtg
    59761 acaaaagtca tgtcacagct ccttttttcc gaataaacat tgttctcctg ccaactcctc
    59821 ggtcacaagt cacaatatcc aataaatata agaagctgtt ttttgaactt gttccttgtg
    59881 actcggagtt aaacggcagg ctcacgacct ctttcttaaa cggtgttcaa tcagctgttc
    59941 ctcggtatta gctcaaaaac cggcaaaata taaggagata tttttccgta tgtttctcta
    60001 atactcaggt caaaacgctg atttcacaac ctcttcctta aacggtgttc aaaagcttgc
    60061 atctgcggta ataagtccaa ccaagttaaa aacattaaga agctgttttt acttggctgt
    60121 tcttattact tgatgcaggg cagctttttc acaacctctt ggtacacggt gttccagaag
    60181 tagcttcttc ggcaataagc cgaaatatca caaaaatttg agaagcaatt ttcgtaaatt
    60241 ccttcttatt tcttgaagct gaccacttct gtcacaacct ctttgattac ttcgtttgat
    60301 tttattttaa tataagttga ttaaaagaga gcatgatttg ttttattttc tcactaattt
    60361 ttccaacaca actaagaata ccataaaagc tgattttgga ggaggttcct actacaagtc
    60421 taaaacgaaa tttaagactt ttcctcataa aatactggtt tattttggtc tcatgtaaaa
    60481 ctcgctgaag gcctcttcac ttataaatgc ttccccagct gccagtacgt ctttcatttg
    60541 gatcgaatcg atgatttcag gaagatcaaa taaagttcga tcgccaaata aactttgcgt
    60601 aaattgattg gcaatatatt cgatcgaatt taatgattgg aaatattgtc caagcatttt
    60661 cttcttcagc aaatcgagat ttgtttctga cacttccgga tcatcagcga atccaagaat
    60721 gatttctttg actttttctg ctgctttctc tggttcgtcc gtatctccgc tgaagtccgc
    60781 aaagtgaaat tcacgatcca agctgaattc aaaaccaaag ctgtcatcga taattccttg
    60841 attgtacatc gctagatagt ttcgagaagt attgcctaaa atcatttgga acaacagatt
    60901 gattgctgtt ttatagcgta acagttctgt tccttcttgc ggcaatgtgt ctaatccttt
    60961 aataccaagt acaaatttat ctcgtgtaat ggctgcttcc aatgcacttt gtttgatgat
    61021 ttcttttgtg ttttcaggga aataacgtac aatttcttgc tttggaggga aattttttgc
    61081 ttcttggttt tcccgaataa gtttcatcaa tttctcaggc tccatcttac caactacaaa
    61141 taaaaccata ttgcttggct gataaaacgt ccgatagcac gtatacaagt cttgagctgt
    61201 gattttgtcg atactttcaa ccgtgcccgc aatatcgata tgcaatgggt gtgtaggata
    61261 caagttattt agtatgccaa aaaacatccg ccagttaggg tcgtcttcat acatttggat
    61321 ttcctgaccg atgattcctt tttccttgtt tacagtttct tctgtgaagt aaggtgcttg
    61381 tacaaaatcg atcagagtcg tcagattctt ttctacctga tccgtcgtag aaaacagata
    61441 gctggttttc gtaaaacttg tgaaagcatt ggcggaagct ccttgtttcc caaataattg
    61501 aaagacatca ccatcttctt tttcaaacaa cttatgttct aaaaaatggg caattccatc
    61561 tggaactttc accttttctt tttcaccata gggaataaat tcgttatcga tcgaaccata
    61621 attcgtactg aacaaaccat atgtcttgtg atagtcattt ttaggcaaca aatacacggt
    61681 caaaccgttt ggcagtactt catgataaag tgtttcattg atttgctcat attctgtttt
    61741 attcatttgc atttcctcct gctaaaaaga agattgcctg caattcgatt tgctcagcta
    61801 cttgttgtat ctctttgatc gttacgctct ccatacgttt caaccattct tcatcagata
    61861 attttgtttc cggcagccag ctgtccaaaa aagaagcttc gattgccgct tgcggagagt
    61921 ctagagaaag cagatattgg tttctcagca ttgcttttgt ctgagacagt tccaactctg
    61981 ttatttcacc atttcgcaaa ctttctaatt gctcgtgaat cagatgaagt acttgatttc
    62041 ggttcttttc atcgataccg gtttggacac tcatgaatcc tcggaacgta tccacgctac
    62101 tagaggcata ataagctaga ctttctttct ctctgacatt catgaaaagt ttagagtgag
    62161 gaaaaccgcc aaataaaccg ttaaagacca ttagcgcaaa acgttctggt tcatcgtaat
    62221 acacatttgt ctgataagct aggttcagct ttgcttgaac gattggctca cgtacttgtc
    62281 gttccttcac gatattcact tgaggttggg tataaaacag atctggataa actgtttccc
    62341 gcgactcaaa tggtaattgc ccaactgctt cagctgcttt gtccggatca acatcgccga
    62401 caacaaaaat gtcgatttga tcatttgcca tcatttcttg atagtaggac gctagcgaac
    62461 tagcagtgat cttgtccaaa tcttcgacta cgcccaaccc tgggatcttt tgttccgggc
    62521 tgttttcaaa ataaagttct tgcaaggcat aggaagcaaa agtttgttta tcttccttca
    62581 aactttccaa atatagacgc agattgttct tttccaagtc aaacgtcaac tgatcaaact
    62641 gatgattttt aatatttgga taaaataaaa cctcttttaa aaaatctacc gcttgagaaa
    62701 aaaggtttgg atcattgaca tattcaccat tcacaaaact gatccctgcg tttagccaat
    62761 gtaaatttcc tttttttcta actgataatc caaagcttgc gccataaagc tctgcaagtt
    62821 gcgcacttaa ctttgtctga tccgaataat tcaaactatt tgtttccaac atgctgctga
    62881 gaagtgaacg tttcgtgatg acttcttgtt gcagacgcgc agtaaaacgg ataaaaatcc
    62941 ggatcgtttt gtattgtttt gttggtaaga catgaagatt cacgccttct gccaattgat
    63001 acaccatatt tatatgctcc ttttcacagt tgattgcccg cttactcttt taatgggtca
    63061 acctgccttt tttacttatt cctctgcttg aaatttataa gttcaggcaa ttcgccgttt
    63121 tttctaaatg atgttacact ttatagtata gcatagatgt tttttatcaa aagaaacaga
    63181 cggctaaaag cgtatattgt ttttttattt tttatttttc gatatactaa agacaaataa
    63241 aagaagggag ggtcattcat gatcaaagaa ttcaaagagt tcatcatgcg tggagatgtc
    63301 ttggatcttg ctgtcggcgt tgttattggt agtgcgttta caagcatcgt aaaccaagtg
    63361 gtgcaaggct tgatcacacc actaataggt tggtttgtcg caatgatcac aggtacttct
    63421 gatttagaag gagcactttc aattcttgac tggtcgccga caaaaggcgt cacatttgcg
    63481 tttggtaacg ttattagtgc tatcattaca tttctgatca ctggttttgt cttattctta
    63541 gttgtcaaag cggcaaaccg tgcgaagaat ttacgctcca aagaagagca agtggaagtg
    63601 gaagaaactc ctactgcaga agattatctt agtgacatac gcgatcttct tgccaaacaa
    63661 gtggcagaag acaatacaca tccagtagag caaacaaatc tttccgatac ttctaaataa
    63721 taaagaatct aaaaaaaaga aagccgattt tcagtgtcgg ctttcttttt ttagattctt
    63781 aacttgctac ttgttccttt ttcatgtcga tatgtggaat atcatcttcc aaatacacat
    63841 ctgagattgc cttgaatcca aacgactcat aaaaagcttg taggtattct tgtgcgccga
    63901 tcacgattgg tttttctgga aaatttttct ggatcatgtt aatcgtttct tgaacaatct
    63961 ttcttcctaa accatcttta cggttgtcct gatgaacaag gacacgtcca aaatggatac
    64021 tctccgcttc ttcatatact cgcgtgtagg caaggatctt cccatcagta tcttgaaaaa
    64081 acgtatgcca agcttctcca tcaatgtcat caacttcttg ataaggacac tgttgttcca
    64141 caacaaaaac tgcgattcgt tctttgacga tcgcgtaaaa ctctgctgtt gacaattctt
    64201 caaatttctt tacctgatat tccactaagc aaacgccccc tgctttttta ttcttagcat
    64261 accgattcgc acacaaaaaa gcaaacgaac cttacgaatc tcaggctcgt ttgcttttta
    64321 aactgcttca gttaaaaatt cgatctcaac tgtccgagta agtacatctg aatagctgta
    64381 agatactcgt tcaaaagaat tttcttcagg atccaaatca acaacgaata ctgaaggata
    64441 ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt cttcctgtct gagcaaccaa
    64501 catgattggg ctgccgatac gaccttctaa atctttcttg attgaagcta aagttgttgg
    64561 catacagttc acctctacta tcaactatac cacatatttt taaaattttc aagtttacca
    64621 taaaaaaaaa agaaatgcaa taaaaataaa taagaagctc attaagattt ttctaaatta
    64681 ttcctcatta taaaatttca agtgtttttt tattttgagt tttactctcc cgtaagcgct
    64741 cattacttgc ttgtgatcca ttgctaaaca ttcagccatg tctacaaaat caacgccttg
    64801 catataataa tgaaaaattt tagcttctat ttttgaaaac tggatttcgc aattttcgat
    64861 tgcttctttt aataaaagat gctgaattgc taaaggttct tgcaatgtga tctctgctaa
    64921 aaagtctggt ccttctgtct ctattttttg gtcgattgag acttcatctt tttgatcacg
    64981 acgcttcagc gcgttctgct tcctcaacag agaatagatt tgattgctta taacgctttt
    65041 ataataactt ccaaagctaa cacctttgct tttttcgtaa gttctcaatg cctgatataa
    65101 agcgatcctt gcttcttgtt cccaatcctc agaaacataa tttcttaaat aataggtgtt
    65161 tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg gcagcaaatg cttcttcgtc
    65221 accattacgt gcagcgcgca ataactcctc agacataaaa taattcctcc ataaattcgt
    65281 ttatggagga atcttatcat caatgattca tcgaactgat tagaacgata tgttatttat
    65341 tttttctcat taaatcgtcc aatttttggg acaatttttt taactgctct tcattccatg
    65401 gagaattacg tcggaaatca ataaaatgca tatctttatt ttcttgggct attgtttttt
    65461 ccgttttttt tatcgtctta tataattcat aagcagaagt tcgtaatgct ccttgggaaa
    65521 agatcatcca ctgttctgct aaatcgcttg tcgccactgt cacttgtgtc aaacggtcat
    65581 tcagctgacc agcgattctc tcgatataac tgtcagccgt ttcgtcttct ttcgtaaaaa
    65641 caacatccaa ctggtatttc ttataatttt gttggatgcc cggaactagt tgggcatcga
    65701 agacaacgat gacttccatt ccttcatatt tcgcataatt tgataaacga tgtaaaagag
    65761 cttctcttgc atccgccatt ttgtcctgct ttttaagctg gacaagttcc ggccacgaac
    65821 caatcatgtt gtagccgtct acaatcaaca gctgtttttt catggtctac tccccctgac
    65881 gttgggaaaa agcctgatac ataagcaaac cagcagcaac actggcattt aagctctgga
    65941 cgtgcccggt catcgggatc gtcagcaatt catccatttc ttttttcaat cctggactca
    66001 ttcctttgcc ttcattacca atgactaaag caattgatcc tttggcattc catttttgga
    66061 agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc tgtttctttg agctgttgca
    66121 cagcttgtac caaattcgtc acgcgtgcaa cagggacatg ttcgactgcc ccagtggaag
    66181 tctttgttac gataggtgtg attccaactg ctcggtgttt tggtatgatc acaccatcga
    66241 cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt gtgtggatct tcgatgctat
    66301 ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt tcgttcaatc agttggtcaa
    66361 gggataaata ttcataaggt gtaatcgcaa gaacgactcc ttgatgcacg ccgtgatcgc
    66421 tcaaagtttc taatttttgt ttaggaaccc atttgactgg cacagcttgt tcacgtgcga
    66481 tttctttcag ttcttctact ttttctcctc gtgaatcttc ttgaagaaag agtttattcc
    66541 ctcgcccttg ttgtagcgct tctactgcgg catggtgccc aaagacgaaa ttatcttcta
    66601 atgcttcttc attttgatca gaaactgact gatttcgtcc agtttgcttt ttatttgaat
    66661 atctattttg ttttttgtct tcaaatccac gtttcgattg atgtttgttt gttctttctt
    66721 tacccatttt tttcaccaac tttctgaata caccagcgga tcaattcttc catccgctcg
    66781 gtttgttttg tcaaatgcag atagcccatg agcgcttcga accctgttgc gacccgatac
    66841 gtcgtaacat cagcattttt tgcgctcgta tggcttttag catttcttcc tctgcgataa
    66901 taaagttctt cttcttctgt caaaagatgt tcttccagca tttgctgaat caaaaaggct
    66961 tgtgcattcg cagaaacata attcgttgcc gcacgatgca gcttattggg ttttgtttct
    67021 ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa tcgcatctcc aacataagcc
    67081 aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc tcttctccat cgggttcctt
    67141 gcggtgtatc ttctaataag atcccttttt ctttcaacaa atcacgaatt tcgtcgcttc
    67201 ggacaaaatc acgattgctt cttgcttgat ttcgttcttc gatcaattgt tcaatctctt
    67261 catctaataa ctcttctgct gtaaataaaa taccgaagat cgaaagccat tgcgagaata
    67321 aagcttctcc ttgtgccaag acagcggcag aaactttcgg ctggtctaga taagtgttca
    67381 gccacttagc aagctcatag accactgtga tcccatttgc tgcattaaaa tcatcgtcca
    67441 tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc gattttatcc gcatcatctg
    67501 ccaaattctc tgaggcagtt tcttggcgga atttcaaatt gtcaaacgta ttcttcagtc
    67561 gttgtaaatt ggtggctgct tctttcatcg tcgtttcact gtagcggatc ggacgacggt
    67621 attgtgtggt cgccatgaag aaacgcaaga cttgtggatc aacgtttttg atcatttcat
    67681 gtacagtgat gaaattccct agagatttac tcattttttc atcgtcttcg ccaatcgtta
    67741 catagccatt gtgcatccag taattagcga attttttccc tgttttcgct tcactttgtg
    67801 cgatttcatt ttcatgatga ggaaattcta aatcttgccc gccaccatgg atatcgatcg
    67861 tttctcctaa atgttttgtt gccataacgg aacattcaat atgccaaccg ggacgtcctt
    67921 tgccccatgg tgaatcccaa gaaatctcgc caggttttgc ttgtttccat aaagcgaaat
    67981 ctaatgggtc ttctttttgc tgctgttctt cccctgtacg ctgacttgct ccgacttcca
    68041 gttcatcgat ggattggtca cttaatttcc cataattttc aaatttacgg gtacggtaat
    68101 acacatcacc tgaagattca taagcatagc ctttttcaac caacacttga ataaatgcta
    68161 aaatatctgg catatgatcc atgactcttg gatgcagtgt agcaggttcg acattcaacg
    68221 ctttcgtatc ttcttcaaat gctcggatga aacgatcagc aacttctggt gctgtaatac
    68281 ctaattcgtt tgctgtacgg atgattttat cgtctacatc cgtgaaattc gatacgaaat
    68341 cgactttata gcctcgatat tcaaaatagc gtcgaattgt atcgaaagca atggtgctac
    68401 gagcatttcc gatatggata taattataca cagtcggtcc gcagacatac ataccgacat
    68461 gtcccttttg tatagggatg aattcttctt tttttctggt caatgtattg tagattttta
    68521 tcattctgat ctcctcactt tttctccttt gattcgaacg acttttgctg gtactcctac
    68581 cgctgtagcg tcgtctggaa catctttcaa cacaacggca cctgcaccga ttttggcgtt
    68641 ttttccgatc gttaccggtc ctaatatctg cgcattcgca gagagcatgg ctccttgttt
    68701 aacagttggg tgtcttttac ccgtttcttt tcctgtgccg cctaatgtta cgccatggaa
    68761 taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg acgattccca ttccatggtc
    68821 gatgaacacg ccagttccaa tcgttgctcc tggatggatc tcaacaccag ttaggaaacg
    68881 ccagaattga gcattgatct tcgccaataa aaagagccgg tgctgatata aaaaatgaga
    68941 gaaacgatgc caaaacaagg catgaaaacc agggtatgtc aaaacgatct cagctgtcga
    69001 acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct cgggtaaacc aactcatgac
    69061 tttccactcc tttcgtaaga attttatgta ggaaatcatc ttcttataaa gaaaagaagc
    69121 gccttttaaa taagtttcct tatcaaaaga cgctttccgc gtggttccac ttttcttcat
    69181 aatcaatgat tatctctgac agctaacgcc tgttatacgt tcttggctac tttgtttcct
    69241 ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc actcccagag gcatttcggc
    69301 aaccattcat tgataccttg caccacccgg tatctctctt gtaatgatca gctgcttact
    69361 tttttctgtt catcgtgttt agttcagtac ttgatttaaa tgtgctaatg atttttcacg
    69421 accaagcaat tcgatcgttt caggcaattc tggaccatgc atttgtcctg atacagctac
    69481 acggattggc atgaaaagat tttttccttt tacgccagtt tctttttgaa cagctttgat
    69541 ggcagctttg acagttggag catctactac ttccatttgt tctagctgtg ctttgaatgc
    69601 gtggagaaca gtaggaactg tttcaccagc aagtacttct tttgctgctt cattcaatac
    69661 aggatgttca ttgaaaaata gcgtagacag atcaacgatt tctgcagcat agctcatttg
    69721 aggttgatac aggctaacga tcttcttcac ccattcgatt gtcttttcat ctgggttttc
    69781 tgctacacgt ccatcagcga ttagataagg cagacacatg tcagtaaatg catctagatc
    69841 cattgctttg atgtaatggt tgtttaccca ttgcagtttt ttcgcatcga aagctgcggg
    69901 tgatttactt aggcgttttg gatcgaacat tttgatcaat tcttggtgtt cgaagatttc
    69961 gtcttcgccc acaggtgacc agcccaataa tgcaataaag ttgaacattg catctggtag
    70021 atagcctaat tcgcgatatt gttcgataaa ttgcaagatt gattcgtcac gtttgcttag
    70081 ttttttacct gtttcactgt tgatgatcaa tgtcatatgt ccgaaggttg gtggtgtcca
    70141 gccaaatgct tcatagatca tcagttgttt tggtgtattg gcaatatggt catctccacg
    70201 taaaacgtga gtgattttca tcaaatgatc atcgaccgca acagcaaaat tataagttgg
    70261 cataccatcg cgtttttgga tgacaaagtc gccaccgata ttatcggatt cgaacgaaat
    70321 agcgcctttc accatatctg taaatgcgta ttctgtattg cgaggcacac ggaaacgtac
    70381 aacagattct agaccttgtg cttctttttc tgcttgttct tcaggtgtca agttcgcaca
    70441 tgttcctgcg taatgaggca tttctcctct tgcgcgttgt gcttcccgtt ctgcttctaa
    70501 ttcttcttct gtgcaatagc atttgtatgc tcgattgcta gcaagcagct gatcaatcag
    70561 cggttgatag atttctttac gttcagattg acggtaaggg ccgtattctc caggattttc
    70621 aggagattca tcccaattca ttcccaacca agcaaggttt tccaactggc ttttttcgcc
    70681 atcttcgata ttacgttttt ggtcagtatc ctcaatacga ataataaagt ctccatcatt
    70741 gtggcgggca aacaaataat tgaataatgc agttcttgca tttccaatat gcaggtgccc
    70801 agttggactt ggtgcatagc gtacgcgtac tttcgtcatt ttcttcctct tctttcaaac
    70861 tagactttga ctaacagcaa aaattccgtc agttacggct tctcaaatat catttattta
    70921 aagccactca gcacaaattt taccttttct aaggtaaata gtaaagccaa ctggttgaat
    70981 ttccttacca gttggctgaa tttctttttt attttgattg tttagtcttt ttctctgtct
    71041 cttttttatt gtcgattcct cgtcctgcat gtgcaggttt agcaaagatc atgcgtccag
    71101 cagctgtttg aagggcactt gttacaacga cttcgatacg ttcattcatg taatgctgtc
    71161 catcttctac gacaaccatc gtgccgtcat caaggtaggc tactccttgt tggcgttctg
    71221 tcccggcttt tactactaga acattcatcg tttcaccagg gatgacgact ggttttacgg
    71281 catttgccaa cgcattgata ttaagaacag gtacattttg gaattcagag actttattca
    71341 agttatagtc attggttaca atgacaccat ctaaaagctt agccaatttg atcaatttgc
    71401 tgtctacttc actgatatct tcaaagtctc catcgtacat ttcgacagat ataccctctt
    71461 ctttttgcaa ggcatttagg atatctaatc cgcgacgacc acgcacacgt ttcaaactat
    71521 cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa attagggatc atcaaggttc
    71581 cttctaagaa tccagtcttt gtaatatcat aaatccgacc gtcaatgatc acgcttgtat
    71641 ccaagatttt atatttatgg aaattttctc ctgattttcg ttctaacagt tgactctcaa
    71701 cttgactagc tgtttcttgc tcgatttttt tgcttcgtga accaaaaact ttcttccatt
    71761 cttcgattcg tgtcgttccc attctcaatc ccagatagcc taagatgatc atcagtaaaa
    71821 tcggcaatac actattgacg aatggaattt ccatattgta aagaggggtc gagatcacaa
    71881 cacctaaagt caatccgatg atcgcaccga tcgcaccgaa gagaagataa gtcaagctga
    71941 cctcacttag tttttgttct acttgtttga taatagctga gatatgtttg gccaacagca
    72001 aagataataa aaagaaaata agtgcgccta acaggctgtt ggtaaatgta ttattcagcc
    72061 atccgtttga ctgttgaccg attgcctgcc aagctgaggg taaaaatgaa atacccaagc
    72121 ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt ttgcatcgtt tttcctccgt
    72181 ttcgacaatc atttattagt tagcggaaca cacgcttcaa cgtttcagcc aaagttgcta
    72241 ctccaactat ctcgattcct tttggcgctt cccagttacc taagttgttt ttaggtaggt
    72301 atacttttgt gaagccgagt ttttggactt ctttgactcg ttgttcaata tgactgacac
    72361 gtctgatttc tccagtcagt ccaatttcac cgatgaaaca ttccgttggc tgtgttcctt
    72421 tttctttata gcttgaagca atactgacag cgatagctaa atcaatcgct ggttcattta
    72481 attttacccc acctgcagct tttaagtaag catcttgatt ctgaagaagc aacccagctc
    72541 ttttttccag cactgccatg atcagagata cccgattgaa atcaagacct gttgttgttc
    72601 gtttggcatt tccgaacata gtaggtgtga ctaatgcttg gatctctacc aaaattggac
    72661 gtgtcccttc cattgccaca acgatagcag agccagttgc accgtctagg cgttcttcta
    72721 agaaaatctg tgaaggatta gcgacttctt ccaatccatg ctcatgcatt tcaaaaatcc
    72781 caatctcatt cgttgagcca aatcggtttt ttactgctcg caaaatccga aaactatgat
    72841 gttgttcacc ttcaaaatat aacaccgtat ccaccatatg ttctaacatt cttgggccgg
    72901 cgatcgagcc ttctttggta acatgaccga cgataaaaat ggctatccca tttgttttag
    72961 cggttttgag tagttctgca gtggtttctc ttacttggct gacacttcct gccacacttg
    73021 tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat aacataatca ggggagatat
    73081 gttcgatggc acgactgatt tcgttcatat ctgtttcagc gtatagataa aattctgtgt
    73141 tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc tgcgctttct tcgccggata
    73201 catataagac ttttccgcct atggctgcta attgctgaga aacttgtaac agcaaagtgg
    73261 atttcccgat acctggatcg ccaccaatca agaccataga ccctggcacc acacctccgc
    73321 ctaacacacg gttcagttct tctaattttg ttttgatccg aggttctttt ttagggacga
    73381 cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa acttgtccga gttctgcggt
    73441 ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca ttttccgcaa tttgggcagc
    73501 gtcccaagaa cttaggcgac acatacccgc aattttggca aacaaattgt acttttgatt
    73561 tttttgccat tgtaccgcct ccttttatcc taatcatgag acattaaatc aagcttaagt
    73621 atctttaacg ttttatttac tggaagaacc aaatccgcct tgacgttgag cagtcgtttg
    73681 atcttgatct gcttttaaaa acggcaaaaa gatcccttgg ccgatacgct cgcctttttt
    73741 gatcactaca tccttgaaac caaagttggt gaattggaac atgatatggc cttcatttgc
    73801 ctcattattg taataatcac tgtcaatcac acctactccg tttgtcaaca ctaaaaaccg
    73861 cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat tcatcttctc ccatgtaagc
    73921 tttgattcca gtaggcacga gggttggttt caattgtttt tcattttctg atacatcttt
    73981 tttcaatcca tctgcgactg tttccaaccc ctttttccag cctgctttcc agatacttgg
    74041 aatcacgacc tcttctgctg cttcaaaatc atagccagca gcatgatgtg tagcgcgctg
    74101 cggtagattg atattttgat ctttatattt agaaataact tcaaatcctc tttttctcac
    74161 cggttttcct ccctaaataa actactccta ttctaacata tccgaggctg taaaagactt
    74221 tctttacaaa ttcttcaaga aattctgcta tcttaaagta aaccattaat tcgttctttt
    74281 tccaaacgac tgcaagttgt acaaaaaaac tattttttac atgactttac tcgtcaaaac
    74341 aagtagaata gaacgaaatt aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga
    74401 aattaaaaat gcaaaacgaa ttattgtcaa agtaggaaca agtacattga tttatcccaa
    74461 tggaaatatc aatcttgcgg caatcgatca gttagctttt gtcctttctg atcttagaaa
    74521 tcggggaaag gaagtgatct tagtctcatc aggagctgta ggcgttggta tgcataaatt
    74581 acatttgtca gaacgtccga ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca
    74641 agccgaactg atgaatatct ataatcaaag attcagtgta tataatcaac agacggcaca
    74701 gatcctcgtg acaagagacg tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac
    74761 attggaacag cttttgatta tggacacgat ccctatcgtg aacgaaaacg atactgtagc
    74821 agtggatgaa ttagatcatc tgacaaaatt tggcgataat gatcagctgt cagccatcat
    74881 ggcaaaactt gtcgcggcag accttttgat cgtcctttct gatatcgacg ggttttattc
    74941 agataatccg actacaaatc ccgaggctca gatgtatcgc tatatcgata aaatcgatga
    75001 aaagattctg gcacaagcag gtggtgctgg tagcacattt ggaacaggcg gtatgcagag
    75061 taaattaaaa gccgcttcta ggatatttga agcaaacagc gcaatgattt tagcaaatgg
    75121 aaaaaatccg gcaattattt ttgatattct tgcaggaaaa gaagtaggta ctttatttaa
    75181 ggaggacttg aaatgactga cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa
    75241 caactagcac ttatgcctac aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc
    75301 atcaaaaaga atcaacaagc gatcattgaa gcaaatcata aagacttaga aaaagcagtc
    75361 gaaaacaata tcagtgaaac gatgcaagac cgcttgcagc tgacacctga gcgaatcaat
    75421 gccatggcta cagagatcga aaaaattgct tcgttagacg atcctattgg aaaagtagat
    75481 gagatgtgga cgaacaccga cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg
    75541 atcggcatca tttacgaatc tcgtccaaat gtcacgacag atgcagctag tctagcattc
    75601 aaatcaggga atgccgttat ccttcgcggt ggcaaagaag cattcttctc gaatcaatta
    75661 ttagtccaat tattgcagca agtactggtc agtgctggcg aatctcctta tgccatccag
    75721 tttgtcgatg atacttctca tgaaactgca ggacagttga tgcgattgac agaatactta
    75781 gatgtgctga ttcctcgagg cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg
    75841 gtacctatca ttgaaacagg tacaggaaat aatcacgtat atatcgataa agaagcacag
    75901 ttatctatgg cagtgaacat catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac
    75961 gcggcagaaa cattgctgat ccattctgag atcgcacctt ttttcttgcc agctattgaa
    76021 aaagaactgg tagaacacgg ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta
    76081 gagacggctg ctttagcaga agacacagat tgggatactg aatatctaga ttatatcctt
    76141 gctgtcaaag tggtcgattc tttggatgaa gcaattgcac atatcaatcg gcataatact
    76201 aaacattcag aaacgatcgt gacagatagt tatgcggcta gtcaacgttt cttaaatgaa
    76261 gtggacgcgg cggctgtcta tgtcaatgcc tccactcgtt ttacagacgg atcggtattt
    76321 ggttttggtg cagagattgg tatctctact caaaagttgc atgcccgtgg tccaatgggg
    76381 ttaaatgaat taacttccac aaaatatatc atttatggcg atggacaaat ccgcgaataa
    76441 tgtttcgtgt gaaacattat tcccgccttt tgcctttttt ctgtaaaggt tctatccaac
    76501 tagaaaggtg tcaatatgtt tgaaatttta atgatttttt ttatttacct tatttctctg
    76561 aatatcgctg cttttctggg agtcggtatt ttatcccttt tctttcaatt caaaaaacga
    76621 agcataggga gtcaacggga aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg
    76681 ctggttacac gcttgcacat tagttacatg gttgcattat gcttattagc gacaatcaat
    76741 tactattctt ttttcgatca ttcaatcgct tatacgatta cgctactgat tgctgggatt
    76801 tttcacttat cttataaata tcagctgaat aaaaaccact tgaatcggac tttccgctaa
    76861 aaaatatccg tacgataagt agagtgcctt gaagatcggc aaaaaactgc cggacttttt
    76921 agaggctgtg acaaagattt tgtcacagcc tctttttcca tataaacggc gttcgcctac
    76981 cagctgcctg gtaaatctgt ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg
    77041 ccatcataat aacgaagcag ctcatccatg gacaagttca tcgttttttc tttttcttct
    77101 tccgctgatt cagccagtag ctgttcccga tacacctgat acataccagc tattttttgc
    77161 tgcatcgctt ttctagtttc accttccgca ttgattattg gcaattcttt gatatagcca
    77221 cgataaatca accgatcatc tgaaaattca atgggtaatt caacgagtgt caacccgact
    77281 tcctgaaaat attcttccag catctattat ccccccattc tttttcttaa atgaatttta
    77341 gcttacctac tgaaaatttt ccagtttcat tattttgaga aaaaaaggga atgtgacaaa
    77401 aatcgtgtca catccccttt ttccgaataa atggtgttct tctgccaact cctcaatcat
    77461 aagtcacaat attcaacaaa catgagaaac tgttttttga aattgttcct tgtgattcag
    77521 agttaaacga cagtctcaca acctcttggt aaacggcgtt caatcagctg accctcggta
    77581 ttagctcaaa aaacggtaaa atatgagaag ctatttttcc gttttgtttc tctaatactt
    77641 aggataaaac gctgatttta caacctctgt taaacggtgt tcaatcagct gtccttcggt
    77701 attagctcaa aaaacggcaa aatatgagga actatttttc cgtttgtttc tctaatactc
    77761 aggacaaaac gctgatttta caacctcctg ataaacggtg ttcaaaagct tgcatctgcg
    77821 gtaataagcc caaccaaacg aaaaatatga gaagctattt ttgtttggct gttcttatga
    77881 cttgatgcag gacagctttt tcacaacctc tgatttctta ttcttcttca tttgtagcaa
    77941 aataattacg gtgataaatg atacaacata cactgataag aacaatggca cctgcaaaat
    78001 aaaacgcata gctttcacca atatgttcac caatcacacc tgcaataaat ggtgctaaag
    78061 ctccaccgaa aaagcggaca aaactatagc tggacgaagc aacgtttcgt tgcagacctg
    78121 gtatttccat agcaatcgtc gtcaacagtg tattgataat tccttggaaa aatcctgcta
    78181 acacaatgct gatcggtaca aggactggca tagaagttcc agctcctaat aacagcaaac
    78241 aaataatgaa taagacaaat gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa
    78301 gagccggtgc aacgaaaatc gaagcaatag ccagaagcac accccagcca aaaaatacaa
    78361 aaccgacttc taattcagaa tagccaatca ataaaaatgg cgcatacgca agtaaagtaa
    78421 agaatccgaa attatataac aatgcgatta gtccaactga acgaagttta tgattgctta
    78481 acgctttgac accttcccaa aggcctactt ttctctttgg tttctcagtt tcaggtaaaa
    78541 gtaccgctag ggctataaaa ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac
    78601 gccatgaacc actgcccaag accccaccga ctagagggcc aacagccatt ccgcagccaa
    78661 gtgctgcttc atacatcatg attgcttttt ctgtgttacc aactaaaata ctgacgatcg
    78721 ttgctaaagc agtagagaca aataaagcat tcccgacacc ccagccggca cgtaacccaa
    78781 tcagcattcc gatattccca gataatccgc caagaccagc gaatacaacg atgataaaca
    78841 atcctgtcat caatgttttt ttcaaaccga tccgactaga taagaaacct gtaaatagca
    78901 tcaccacacc agtgactaac atgtaactag taaataacag ggtcgtttca gctggcgtag
    78961 cgtttaactg tgcagcaatc gtttttaaga ttgggtctac tagacccact cccataaaag
    79021 cgatcataca ggtagctgct acaactagcg ctgaactttt cccctttgtt tcttcatttg
    79081 tttgttcttg tatatctatt tgattctcca atatttccat ccctttctct ctattagcat
    79141 catacatgat ttattttaca tgtcaatatg cacatgtaaa acgtggaaac tttactgtga
    79201 tataataaag aaaataagac gagaggtagg atttttatga atactttagc ctatatatta
    79261 ttatgcgtgc ttttatccaa accacgttct gggtatgaat tgaagcagct gatcacaatt
    79321 ttttgggaag cccatcacag tcagatctat acaacgcttg ccaagttaga ccagcagggt
    79381 tatgtgaccg ttttggacaa agacgagcac tctcaaaaaa agatctacca cttgactgat
    79441 gaaggacgtg ctcttgtaga ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa
    79501 gatgaatttc tagcaaaaat ctatgctttt tcgacgctcg ataaaacaac agctactgga
    79561 ctgctattca ctagagaaca acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg
    79621 aatgacctct cgctagacaa gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga
    79681 attatgcttt gtcagcagga actccaatgg tgtcagcaag taagagaaca aatgcagcag
    79741 ttttttgagt aagggataaa cagaaccttt ctagaaatat ctattgaaga gcaaattatc
    79801 ttcaataaaa gagcaataca gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc
    79861 tatcgttcgg atcactattt ttctagaact gcattcaaga gactatgaca aaaagcatgc
    79921 caaggccttt tttcaaataa cagtgttcca tcattcatta ctttgaattg cttttagcac
    79981 acttcttgaa agcgggccaa cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat
    80041 tttccaagca ttcatataag cagagaataa ttgatcaggt attccttgtt ccatgatcac
    80101 accgaataaa gacatacatg tcaccattcc taaaaccatc aagcatgaaa tagttaagat
    80161 catttggacc ttgctttctg gatttactgg tagtttaaag gcaatttttt tcgccagcac
    80221 accgatgatg aagacatcca aaatgaaagc caccacgaat ccaggcacta gaccaatcaa
    80281 caaacttgat aaatgaagat cttgatgcag ccataaatta tacgcgctca tccccaagac
    80341 catcaaaaaa cacatcattg ttgtaaaaat tattccttct tttttatttg taggcaatct
    80401 gtaccactcc tttaaatttg tcacgaaaat catcgtagca catttaaaaa tttctcgtaa
    80461 gtactttttt tattttctgc ccttttattt cataaacttc atcagccgta cgctcgacaa
    80521 agtaagaatc atgagaagta aacaaaatcg ttcccggata tatttgcatt agcttctcta
    80581 aagcttcgat cgttgccata tcaataaaat tagtcggttc atctaacagc aacacattac
    80641 ttggcttagt aaaaagcaaa gcaatcgtca gacgggtcgc ttctccccca cttaatgtac
    80701 ataacggttt cgtcaaagtt tcctgagcaa accctaagtg attcagcaaa ctacggacaa
    80761 gcgattctga aaactctgtt tgtctcatga caaaacgaat gatggattct tcagatgtca
    80821 tttgataacc cttttgctga tatacttgaa agcttacttt cggagagaga aggattcctt
    80881 ctccttgttt gcggatatgt tctaataagg ttgtcttacc tgaaccattt tcaccgacaa
    80941 tcgcgatttt tttacctaaa gaaaactgaa aatcaccatt taccagtaat gttctcccac
    81001 ttctttccaa ttggacattt tgtcccatga tgggatagcg gctgtggagt tcaagagatt
    81061 ttggtactgg aaaacggatt tgtttcatct gctgcggctt ggttgtttct cctatttttt
    81121 ggagtcttct ctctaatgtt ttcgcattct tttggatggc tttttgtaca ctgtcttttt
    81181 gtttagagga agacaaccga tccagtctga tttgttgctt tttcttttta ctggacactt
    81241 tttccaactt ttccgcttgt tttttctttt cttggatcga tttttccaat cgttttttct
    81301 ctttcatgat cgactctgct tctcgtagct gagtcttttt ctccaattcc ttttgagtga
    81361 gataggcact ataattcccc gaaaactctc ggatttctcc gtcttttact tcccagattt
    81421 tcgatgctag ctcatctaga aaatagcgat catgactaac aaaaaccagc gtaccataat
    81481 aataacgaag ctcttcaatc agtcgatcaa tactttttct atctagatgg gttgttggct
    81541 cgtctagaag catcccttgt tcataagaag aaagaagacg tatcaactcg atctttcgtt
    81601 cttcccctcc gctccatttc cgctctgaag tttcttccag tcttaactgg aaatgactgg
    81661 ctaattccaa atttaggtcc tttgcttcag cgagataggt taattgaggc aggtagttga
    81721 aggtgatctc tgtttggatt ttcccatgat cgggaaaaag ttcaccggct attagtttga
    81781 gcaaagtcga tttaccgaca ccattttctc ctatgatccc tatacgatct tgctgataga
    81841 cacgaagaga atcaatagat agttctagct ggttgccaaa gctgacttgt agatttgtta
    81901 tatttactgc taaattttcc atatgtttta cactcctatt tcatgtaaaa caacaattat
    81961 cgatactaaa aaagagcaga aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta
    82021 ctctgaacga aataactatg actaaatcac caaatctgtc atagctttca cctattctac
    82081 tgtcgttcga aaaaatggac atactccatc catgaaattg ttgtttatac atgtcttttg
    82141 aatttattta gttgttattc aaaagttcga aacgtaattt catcgatgca gtcatttttc
    82201 cgacctcctt ttttattagg ttaccacaca cgattcaaaa aaagcaatag ctactgaata
    82261 gtaactgaaa accttttatt cgaacatagt gatcttttct ggtgctaaac gaacagactc
    82321 gtaaccttct tctaccgctt ttcctattga taaaataata actggaacat aacggtcttt
    82381 atccaaacca aatgcctctg ccaactgatc tgcttcgaat ccaccaattg gatttgtttc
    82441 atagccatga tcacgcgcaa ctaacatgaa ttgcatagcc gctaagctag aatcgacttt
    82501 gactacatcg ttcatttctt ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa
    82561 ttgttgatct ctgacttctt ttggcatctt ccctgattcg taagcttggt tgtagatttc
    82621 ttcgccatat tcgtaacatt gcatatcgcc aaaaatcatg accattgcag aagaagtatc
    82681 attttgtctc gtattgaaac ggatcaaagg acgcaagatt tcttttgctt cctcgctttc
    82741 agcgaccaca aagcgccatg gtttcatatt gacagaagaa ggtgcagtcg tcgcttcttt
    82801 gatcatttcc agcatttctt cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga
    82861 tcttctacca gtcataattg ttgaaaaatc atttttttgt tccattatta ttaacctctt
    82921 tcgtttctgt tgttatattg caaagttggg tattcaattt atctaaaagt gttagaaatt
    82981 gtttcatttc tacatcgctg aaagccgggg atagcacgga acctgtatct ttatggtcca
    83041 tttcacaatg cttgattttc ttctgggctt tttctgttag cgctacatac acttcccggt
    83101 tgttctgagg atttctctga cgcgaaacat agccatttgc ttccaatacc ttcagatgac
    83161 gagtaactgc tccttgatca atctgcaact tttcttgcaa actgctttgt agcaatggat
    83221 tttcttcttt cagtctcatc atgatctcgt atctagtaag acttataccg atattttctt
    83281 caaagatctg gacgattttt tgatcggcta atttgatttg atataaaagg tgactaatct
    83341 cttctaaaga cataatttcc tcctttctaa taattgactc gtcaacgatt gacttgtcaa
    83401 taatagaata aaaaaagaaa aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc
    83461 aatagaaaag tatagagaaa agaaattttt tgtagaatga acggaaaaaa tgataaagaa
    83521 agcacaacgc taaaaccaag attattgatt cttatcaaac tatagaagat agctcttctg
    83581 cagtagataa ttttacaccg ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg
    83641 aatattagaa attggatcag tatgcttaaa cagtaataaa aaagttatga caagatgttg
    83701 tcacaacctt ttttgagtaa acggtgttca aaaacttgca tctgcggtaa taagttcaac
    83761 caaacaaaaa acatgaaaat ctgtttttgt ttggctgttc ttactacttg atgcagggca
    83821 gctttttcac tacctctttt taataaccat aaaatcctat tccttcatat ctccagccca
    83881 tcggtgttag ccaatctctt tccttagcac tcaaggtata gtgatgggta ccagtttttt
    83941 catttggatt aaatagtcga taaattggct tggaaccacc agaataaaaa cttagacctt
    84001 cataacgcca accgattttt gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat
    84061 ggtctccact gtaaggattg tataaacggt agacaggttg tccgctgttt ggtgcttgcc
    84121 aagcaatccc ttcatattcc cagcctacag ttggcagata atttttttct ccggcattca
    84181 atgtatataa atgttctcct gtatgacggt tatacagacg atacatcgga gaagttgaag
    84241 ttggtgctgt atcatactgt gtcagattat aggtttcgat tacattgttc aatgtagaac
    84301 cataattagg cgcagtggca taacgacctg ttagccaagc cgtagcatct ttgtaagagt
    84361 tcgtattgct tttccatgca ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct
    84421 tcaataccgt tacgttatct tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg
    84481 cattcaccgt aatccattgc ccattcacat attccgaagt aggcatcgta acagattggc
    84541 cattatagct tcctttaatc ccaaatagat tgtaattagg ggcagaagcc aaagtactgt
    84601 tcccccagcc actttcaacg atggcttgag caatcatgac tgatgcatat aagtcattgg
    84661 cacttgccaa actttgtgca gttgaggcaa tactatcaat gaacgcttgt tgagaattag
    84721 cagatgagcg agcataaaaa gcatagccag tatagttttc gaattcagac aaatctgctt
    84781 gatgggtatg tgtcaatgtt tgcccatctg tcaattggtt cgtgatttct tctgcattct
    84841 ctggattgtt ctgagcttct gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt
    84901 cagttgttgg ttcttcggtt gaaattgtat tttctgagac agtagctgac tgcaaagtac
    84961 tttctgtatc gttttcaatt cctgtttctg aagaactcga tgtctgagtt gcgacagttt
    85021 ctgtcgattc ttcagctagc actgttgtgt tggcaactgc tagatttcct aaaagaataa
    85081 cgctaaataa taaattcttt gctttcatct tttttctcct ttgaattatg aaacttttcc
    85141 taaataacag tgtaactaaa aaagtaaaag caagtcaatg tccatattta aataacattt
    85201 gtttcttttt aataaatttg ctttttctgc ataaaaagac gtaaatgaag aatattcttc
    85261 tccattcacg ccttaaattg atggtcgttt gaataactat ttaacaagta attctctctg
    85321 gatattatcc gttatggatt atacttcctg tgtcgtcgga cggataatca tgttgctgac
    85381 agacatccgg tctggcgttt ctatcgcaaa tgctacagca gaagctatat cttcagatgt
    85441 taatccccat tctttttgcg cttcatgaag ttcaagagca gcctttttgt cgctgatggt
    85501 ttgatataat tcagtttgaa cagctcctgg agagatgatc gtagatttga tgttattttg
    85561 ccgttgctct tgacgtaatc cttccatgat tgcacggaca gcaaattttg ttccgcaata
    85621 aacggcggaa tcaggataaa caacatgtcc cgccacagaa tcagttgaaa tgatatgccc
    85681 agatttttgt ttttccatga ttggaagtac ggcggaaatt ccatttaaca cacccatgat
    85741 gttgatatca agcatatttt gccattcatc acggtgacct tcaactaatg gagcggttgg
    85801 catgattcct gcattattgt acaatacatc gattcgaccg aacttttcca tcgctaaatc
    85861 gataactgct tggacttgtg caaaatctct tacatctgct gtttgaatat atagctcagc
    85921 ttctggtaaa gattctttta ttgcttttag gcgatcttct cggcgtgcag ctataactag
    85981 tttagcccct ttttctgcta atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc
    86041 catgatgaca atcacttttt ctgataaatc attcattcta ttctcctcct gttttgaaaa
    86101 atctcttgct tatactcact atctcttatt tcatcttact gttcaaataa tccgttcgac
    86161 aggtttgacg attttggcag ggattcctgc aacgatggta ttgtctggga catctttcgt
    86221 aacagttgca ttcgctgcaa caatggcatt ctcgccaatc gttacgcctg gcagaatagt
    86281 tgctcctgct ccgatccaag catttttctt gatgtggatt ggctttactg acaagcctct
    86341 tcgttctttt ggatcggtta gatggttcac cgtgatgagg ttgacacgag gaccaatcaa
    86401 tactgaatct tctaaacaga tgccacctaa gtcaacgaac atcacttgac gattgataaa
    86461 gacatttttc cctatactaa tatgtttgcc gaaatctgta taaaaaggca gcagaacagt
    86521 caccgtatca tctactttgt cactaatgat attttctagc cgtttgcgga tatctgctgg
    86581 ttcatggtac ccagtattca gcgctgctaa aggctcttcg ttttccgctt ggatctgatg
    86641 gatcacttca aagagcggat ccgttactcg aatctcttta ttgacgattt gtttttcgat
    86701 gaggcttgtc attttgctcc ctccttttat ccttacttta taacggacgg cttatgatgt
    86761 ctaatactta taaaacatac ttaactattc cttttaacta tacttagtgg tatgcttttt
    86821 taaaaacagg agggaaaaaa tggatattcg tatactgacg tattttttag cagtagctag
    86881 agaaaaaaat atcagccgag cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa
    86941 acaactgaaa gatttagaag aagaacttgg tgtgacactt ttcactcgag gctcccgaga
    87001 gatacagttg acggattctg gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt
    87061 ggtagaaaaa acggcgaaca atttaacaaa tgacgcaatc atctctggag aaatctacat
    87121 tggcggaggc gaaactaaag caatctcttt catttctgat agccttcatt cgttgatcaa
    87181 ggcgcatcct gatatccagt ttcatttata tagcgggaat gcagatgata tcatagacaa
    87241 actggatagc ggattacttg attttggact cgtaatcgaa ccgacaaaca aacaaaaata
    87301 ccagtcattt cgactgccag cccaagatcg ttggggactt ttgatacatc ggaatcatcc
    87361 tttagcaaag caaacagtca tccatccgca ggaactgaaa actgttcctt tgatcatttc
    87421 ccggcaaacg tcagtggaca gtcaactagc tgaatggcta ggtttcagca tagatcagtt
    87481 atcgatcgtc ggaacatata acttattgta caatgcttct ttgatggtcg ataacgggac
    87541 ttttggtgca ttagctctag atgggatcat caatacttat gggacggaaa aagtattcat
    87601 cccactcgat ccgccattac aagcttcact gaatctcatt tggaaaaaag accagcctct
    87661 ttctcctgct gctcgtaaat ttttagatgt cctaacggag aaatacagtt aagtagagtt
    87721 tttttccttc gctttcagct ttttaacaac gaataagtta agcaaaagat ccaatgatta
    87781 aataacataa gtttcttaat ttgttccttc cttttatttc tgataattcc agtaaattac
    87841 tataattata aaaaaagaat tgacaaaaca taactgtcta tataaaattg attacgttaa
    87901 caataattcg tttcatgtga ctagatcata ctaggcatga aaaatctctg aggaacatgg
    87961 tttccctagg aggtttttcg tgtctatttt tgtttggccg caatcaactg gtctagcaaa
    88021 cgtgaaaacc aaatcttcaa aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa
    88081 aatgcagtat tggtagatga cggtggacag gaaaaagtag ctattggaaa agggattgga
    88141 tttgacagaa aaagaaatga tttgattttt gatcgtgatg tcgaacggat atttgtcatg
    88201 gaaccagaag gtcaaatcaa gttgcaaaat ttacttaatc agattgatga acgcttttta
    88261 tttgcagcag aaacgatcat tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa
    88321 catgtattga tcgctttgac cgaccacatt gctttttctg cggagaacat taataacggt
    88381 atcgtcatcc gcaacaaact tttaagagaa atcgaagtgc tttacagtga tgaattcagt
    88441 attgctcaat gggcagtaga gtatctgaca aaagagcttg ggattccata tacttatgac
    88501 gaagcaggat atatcgcaat ccatattcac agcggacgaa gcggtcggaa caataaccat
    88561 cgcagtatcc gtgaagtgac gattgtatct gacatcatcc atttagtgga atcagaattg
    88621 gaaacagata tccattcaga accattttca ctgaattatt caagactggt gaatcattta
    88681 cgactgcttc tacaacgaac ccatgcgcaa caatatgctg ttttagacac ggaaatcgta
    88741 gaaatggtca aacgaaaata cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg
    88801 ctgaccaaag aataccagct cgcgatcacg aaagaagaac tgggttactt ggccatccat
    88861 atcgagcgtt taagaagcgc aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa
    88921 aattgaaagc atatctacaa cgaatgggac gttcccttca acttccagtt gcggtcttac
    88981 ctgctgctgc tttactagta gggatcggaa actggtgggc atcttatagt aacgacattg
    89041 tcgctcattt tttacaagct ggcggtaacg cagttttagg tcaattacct ttgctgtttg
    89101 ccgttgggtt agcactaggg atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt
    89161 tggtcgcatt tgaagttcca gtaaatgttt taaaaactga ttcagtagct actttattga
    89221 atatcaaacc agaatcagtt gatccatctt ttgctcagat cagtaacgta tttattggta
    89281 ttattgccgg attgattgcg gcagctcttt ataatcgttt ccacgaagca aaattaccga
    89341 tggctttatc tttctttagc ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt
    89401 tgctgatcag tgcagtgcta ctgctcgtat ggcctccggt ttactctgct ttagtttctt
    89461 ttgctaaatt cattttgagt ttaggctggg gtggtgcagg tctttatggc ttcttcaacc
    89521 gtttactgat ccctacagga ttgcatcaag caatgaactc cgtgttctgg tttgacgtag
    89581 caggaatcaa tgatattggt aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa
    89641 tgtatcaagc tggatttttc ccaatcatga tgttcgggct tccagcagga gcatatgcta
    89701 tttacagaaa tgcacgtcca gaaaacaaag caaaaacagc ttccttgatg ttagcagcag
    89761 cttttgcttc attctttact ggtgtaacag aaccacttga attctcattt atgttcgttg
    89821 cttggccatt atatgtcttg catgcaattt tcactgggat ttctttagca gtgagtgcat
    89881 tcttccattg gacagcagga tttgccttta gtgccggatt tgtcgattac ttcctatctt
    89941 tgaaaaatcc gattgcgaat cagccattga tgttgatcgt ccaaggatta gtaacagcag
    90001 tgatttacta ctttggcttt aactttgcta tcaaaaaatt ccatctgatg actcctggcc
    90061 gcgaggaagc agatctttca gatgacgata ctgcaacgac taattcagac aataaatatg
    90121 cggcacaagc aagcaaaatc tacgctgcat taggcggagc cgacaatgta acttctatcg
    90181 ataactgtac tacacgcctt cgtttgcaag tcaaagatac aggcctgatc gatcaaaata
    90241 aaatcaaagc cactggcgta cctggtatga agatcatcga cggaaaaaat gcgcaagtca
    90301 tcgtaggtac agaagtacaa ttcgttgcag atgagatggc aaaactacat ggtggtgctg
    90361 caacacgacc tgcacaaaca aacaccgtgg ttaaaacaga aacatttgcc ggtggaacga
    90421 tcgaacaaga tatttacgct atcgcaaatg ggaaactgat tccaatcact gaagtttcag
    90481 atgatgtatt cgcggaaaaa atgatgggtg acggctatgc tgtattacca gaaaatggag
    90541 aaatcttctc tccaatcgct ggtacgatca caaacatttt cccaacgaaa catgctgtcg
    90601 gaatccaaac agatgctggt atcgaagtct tgcttcatat gggcatcaac actgttgact
    90661 taaaaggcga accattcact ttatatgtaa aagaaggtca aaaagtcgca agaggtcaat
    90721 tgattgcttt agttgatctt gccgctattc aatctgcagg caaaaacacg gatatggtcg
    90781 ttgtattcac aaatggcgac aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa
    90841 aagcaaatga taaaatcggc tctgtttcca acaaagcctg agccatcgtc ttccccagac
    90901 ttttttatcg ataaacaaac aggagctgag acaaaaatct tgtctcagct cctttttccg
    90961 aataaaaacg gcgttctcct gccaactccg cggtaataag tccagccaaa cgtaacatat
    91021 gaagagctat tttttatttg actcttctta ttacttgatg cagaacagct tttttacaac
    91081 ctctgataaa cggtgttcaa aaaccagttt atcggtatga agtcaaattt atgcaaaaat
    91141 gtggaaagcc attttcacaa aatttttctt catactcaaa actaatcggc tttttcacaa
    91201 cctctttata cattattcct gatccaatat ttcttttaat gctgcttcaa gagaagttaa
    91261 tggttttccc aatacttttt ctaaatcatc agaggaaata gctaactgat cctttttaat
    91321 atcatgttgg atcgctaaaa acatgtcagc tgcttcttga gggaatccgg cttcttttag
    91381 attttcgaca aacgctgcat cacttgcttc aataatttct aactttttac ctgtcgcacg
    91441 ctctaatgcc ttggctaatt cttcatagtc agttagattg ccggataatt ctaagatttc
    91501 tggagagtca ctttctacta gtacttttgc tgcagcttct gcatattcac gtttcaatgc
    91561 ccaacctgtt tttccatttc ctgcagcata aacgaattga ccagttttta aagcctgccc
    91621 aatgataggt aattcattct ctacatacca attattccgt aaaaatgtat gggaaatacc
    91681 tgaatcctta atcatttttt cagtgaattg gtgatctggc gctaatacac tgatcgagtg
    91741 atcggcatct gcaaaacttg tataagcgat ataagatacc ccagctgctt gtgctgcctt
    91801 cactacattc ttatgttcgg cttgacgatt tcctggaacg ccagagacaa aaagcaatcg
    91861 atctattcct ttcaacgctt ctttcattga gtctaaatca tcataatcac caatacgtat
    91921 attaaatcca gcttctttca gtgcttctcc tttttcttca ctacgtacta gtacatagat
    91981 ttcattttgt ggaaccatct tttttaagaa ttccagcgca taaccaccaa aacctccagt
    92041 tgctcctgtt actaaataat gcatatttgc cactccctat tctttttatt tgttaagatt
    92101 tacagctgta catttataaa ttacaccttt atcataaaga gtgtggtaag ataagtcaag
    92161 caaaaaaaat gaaaggatga caactgatga agtattctct gcaatttagt gatgcaatcc
    92221 atgtacttgc ctatattgaa atgtttcaag atacccgatc actttctagt gagatgattg
    92281 ccagtagtat cgaaacaaat gcagcaaatg tacgtaaaat catgagtcag ctcaaaaaat
    92341 ccggtttgat ctttacaaaa accggaaaac cgcagccttc ccttgccaaa agtccagatc
    92401 agatttcttt actagatgtc tatcgcagca tcgaaggtaa tacacagctt atccaagtcg
    92461 atccaaaaac aaatccaaat tgcgtcgttg gtgcgaatat ccaagaagct ttagaagaaa
    92521 gctacgctcg gctgcagaaa aaggcagaag aagaaatggc taagatcaca cttgatagtc
    92581 tgatacataa aatagccgtt ttggaaaaag aaaaaagacc agaaaacaca ggcctcgtag
    92641 agagattttt ataattctct ctactgtgcc tgcatttttc tgatcggaat cgtctacata
    92701 aattctttta ttctccgggg gacaaaagcc ttgtcatgcc cctttttcct ctctaatgct
    92761 caggtcaaag cgctgaagtc atgacgtctt gataaacggt gttcaagtag ctgaccctcg
    92821 gcattagttc tgaaaaatgc aaaatatgga aagctatttc ccatttttcc tctctaatgc
    92881 tcaggtcaaa gcgctacttt cacgacctct atattatcat ggtttattga ctaccggtat
    92941 ccagatttct cccatatatt tcccgttggt aactcccatt tcgactacag catttggacc
    93001 cccaacatag gcgtaatctt ctacttctct taaaacatgc ccaaaggccg tattcgtcaa
    93061 atcatttctt aattcttcag gcgattctgc taaagcgatt acaacaagat acgttccttt
    93121 tgggaatggg atgattcggg tagtgtttgg aacatcctga ctcgtttgaa caccgacata
    93181 gtacatcatt ttcccgttat agggttcgtt gactgtaaag aaataatgat tttcagcagc
    93241 ttgtttcaat gcatctattg ttccattacc gataactttt tgctcaaatg cttgtttctc
    93301 tgcagccaaa ccgacaaaat ccgtattgct actcttcaat tccacaccaa tacccgtcac
    93361 cgtaaaatct ggtttttctt cgatcctata ctttgccatt tctcccaccc tttctattat
    93421 attaagttca tcttacataa aattaaaggg aaatgacacg attacgctct tttttctagg
    93481 gatattttta ttttttaact atttttttgc tttcactgca atccaaatct cactgtaaac
    93541 attactgaaa tcctctcccc attttgtaaa agagatctcg ggagcttcga ctaactcata
    93601 atctgaagaa ggaagccatt ctgcatagat tttcccccaa gtatcttgta aagtttgggg
    93661 aaatggccct ttattaggaa aaatggccca agtgtgttct tctatagcaa gcatttctaa
    93721 atcagcgtac ggattttctt ttgtcgtagc aaagccaatc atgtgcatca aactgccctt
    93781 ttcttccaag cgggctccat caaatccata agaaacgttg attacttgat ttggatataa
    93841 atctcctaac ttatgcatct cttccctttg agtctccgtg atcgtctgcg ctaacttttg
    93901 tatttcttga ttgactcctt caaatttgac aggaactttt ttcgccacac ctgccacata
    93961 aaactgttct ttcttttcga tacgaaattc catcgatttt cctcctctga catcaataaa
    94021 aaatgtcaag cgtggaaaag atttttgtat gccgtatctg ctgatttctg aaggcagata
    94081 tcctgaccaa tcacgaaaag ctcttgaaaa accttcgact gtttcatatc catatctaaa
    94141 cgccgtttct gtcactcttg atccatctag gagatcgcga ttagccaaag ccaatctacg
    94201 gtttttgata tagtccatta gcgacatccc tgcaataaac gtaaagatgc gttttaattg
    94261 atattcagag attcctgtat tttcggctat tattttatag gaaagtcctt ctgtcaaatg
    94321 ttcttcgatg taatcgatca attggttcag atctttaagc atatttatct tcctccttgc
    94381 ttgccttttt atcatattat caaagaaagt caattacttg atgaatcagg aaccaattta
    94441 gtcagatgta gaaaatgttg tatggatcta aagaaaattc tcaagcagcg tttcgtaacg
    94501 gataattggt attatctgcc tatctatgtt ttacctttag aaaaataaat tttggggaag
    94561 acacattcta agtaaacaaa gcggtaaaaa tatcttttat tcccttagtt aatccgctta
    94621 ctacctactg tacaaagcaa attgttgttc aaactgctga tcagaacgct gcttggattt
    94681 ttctttgcga tacatcatac ctcttttatc aattggaaca attatttatt tctaacaaaa
    94741 tcacttcatt tttgtcagat aaataaaaaa caaaaaaagt tccatcttta aaacacgcta
    94801 ttcttttact ttttctcaca ttctctaaga aaagaaaagg agaatgaatt tttgacaatt
    94861 cgagcaaaag tgattatcaa atatgtaaaa tcagctactt ttttcttaaa cgtttcttta
    94921 tactaaatat aaataagtgt ttcatgaaag gagaactaga tgaataattg gcttgagtat
    94981 tttcctgaaa acgttttgga acgcggttac agctatcatc tgcacggttt tgtccgtcat
    95041 ttgaactata caagcaagta cttgtccgca acagtttctg gcacggaaga ttataaggta
    95101 gtgatcactt gggatgaaaa gaccaacatg acttgtgatt gtctatatgc catagaagga
    95161 aaaaaatgca aacacatggc tgctgtctta ttcgcttacg aagaacgtcc aataaaaaaa
    95221 tccaactact cactttccga actctcgtcc cttgtttcct ccgctagttc ctctcttgta
    95281 cgggagcttt taacagagat tcttatagaa catccgcaat ttatcgaacg cttcaaagtt
    95341 aagatgccat ttcatgcaat aaattattca gataaattaa caactatcat ccataaatac
    95401 gatcatatta tcaagaaaaa caaaaacagg aaaacagcga agttcatcat ggagatgcga
    95461 aagttcatcc aagaagcagt tgaatcgctc attcagcaaa atgcctatct tcccgcattc
    95521 gaattgatca atgaagtgat tgctactctc gaaacattct attgggagcc tgaggatgaa
    95581 cgaacccttc ttctgataga ggactgttat tatttatgga aagaattatt agcagaagca
    95641 cctcatgcag aaaaaaggca aatgttctct tggttcgtct gccaagtcga tcatactgac
    95701 gcctcttatt caaaacgcta ctccataaaa atcctgaaag aagactttcg ggaaaaagaa
    95761 ttttctaacc aaaagaaaaa aatagataaa aaaactaaag aaacggtaaa gaaagacgat
    95821 ttcaatgaaa aatagcaagt aaacgataac aaccatccta aatccacaag aaatacagca
    95881 gaccttgctt taaaaacacg aatcatgcaa aggatgaagt aaagaagact taacgcgtac
    95941 ccaatattag tcatttgact attaggtacg cgttttgttt tataagtcat gacaaatttc
    96001 cttcgttgct gggtagattt tccggcattg ttgatagatt ttatgatact tttctacatt
    96061 ttgtaagaga ggttccactg catctgtata ttggataaaa ttctgacaac aactttcagg
    96121 tgtgtcgaac cactctaatc tttaaagata aatattaaaa taacgattaa taatattaac
    96181 agtctttatt tttcaccacc aaaaacctat ctttgcatat actaaataga cgtatataca
    96241 cagataggtt tgtcttgtga aaaataatga ttatccttac caaaaaatgt ttgtttttct
    96301 acatgttcgt acttatcaaa aaatatgatc cttattgaaa ttactggcta tttatattcc
    96361 aacgacttct tgtgttaatt tttgttatct catagtaaat tatgtttcat tttcacttaa
    96421 tttagttgtc acgtgttcgt caattcgtaa aaacggtaaa tatataaaca cacttgcggc
    96481 tataattaat atttgtaaaa cagctgctcg ccagtctccg gctgttgcta aaaatcccga
    96541 tataactggt ggcgtagtcc aaggaatttg cactactaca tgattaatta atcccacagc
    96601 agttgcaaaa tatgctactg tcaaagaaaa aatcggtgca agcacaaagg gaataatcag
    96661 actgatatta aatacaatag gcaatccaaa aataataggt tcgcttatat tgaatatagc
    96721 gggagttacc gataatttag caaagtcctt ataatctttt ctacgactga agataaatat
    96781 tgcaatcaat aaagcaatcg tatttcccga tccacccatt accgcaaagg tatctttaaa
    96841 ggccatattg ataatatgtg gaatttgctc tttgtttgca taagctgcca tattttcttg
    96901 catattctga atcaaaaacg gatctaacaa tgaacctgat attactgctt gatggatacc
    96961 aaatccaaaa aatagattag caatagatgt aattaacaaa aatcctggta aaccagttgt
    97021 aattttactt aatggctctg taactatcgt ggtaattagc ttatttatat ccatattaaa
    97081 caattgaatg attataaatg acaataaagc aaacgaggta atcgtaataa tgattgggat
    97141 taatacatta aaagacttta aaacagcggg aggaatattt ccggatagct gaatctgtag
    97201 tttcttatta ttagaaagtt taataaataa ttctgtagcc gctaatccaa caaatatacc
    97261 tacaaacatt cctgaagctc ctgtatagga tataggtatc acacccgtca cttcaacagc
    97321 tttatccgca ttttcaggag taaacatcat ctgcataggt gttaatacaa caaatgtcga
    97381 aatagcaact aataccgctg caatatgatt tgtataattt ctgcttgcac acatatgata
    97441 agatactgct gctacaacta ataatgtagt tatgcttaat gtaccattgg caattgaagt
    97501 accaatttgt tgtaacgtgg tcaatgtact agtatcgaca atttccccca tgaatcctgt
    97561 tggttctaag atcactgaat taataagtgt cacaaatcct gctaacatca taaatggcat
    97621 aaatgtagca aacgcatctc gcaaagttct taaatggatc tgattcccca acttagtcgc
    97681 aactatacca aatttttcaa atacaatgtc cttcctgcta cttttgccca tattttttct
    97741 cctttatgct tattgtaatc gattactttt tccacccaaa taatacatca cttatcaaaa
    97801 aaagtaaata cttttaatta aatatatata tcttttttag tataaaaaaa taagctctga
    97861 aaaaataatt ttcccgagct tatttttcaa caaaaacagc ttcaaaaaca aagtcttgat
    97921 ataaatgtct cgataccgaa tactcgaaag gtttaccaga cgatagagca acaactttgt
    97981 ctatctcaat cataaattca cctggatcta tttttaatat ttttgcgtca aattcattcg
    98041 cagtatctcc tttgatacgt atgtgcgaag tctttatttc cagacccagt tcatttgtga
    98101 tataagcata tacagatttc tttaaatgtt ttggttccaa gcctggtatg actgctaatg
    98161 gcatgaatgt ttgctcaatc gagtatggtt gacaatcaat aaaacggctt cgtacaatat
    98221 tatatacata gtcttttaca ctgatactta atttatcagc tacttttttc gatggaagtt
    98281 caattgagaa agtatggatt tctgaatcta cgtgttcttc accaaccacg ctaaacaaac
    98341 cttcgtttgg accaagaact cgtgagttat caattggtgt tctgacgact tcagtcccat
    98401 acccacttct acttcgcaaa actccttcgg aaacaagtaa gtctacgcct ttctttactg
    98461 ttaacttgct tgtatgataa ataactgcca attcatctcc tgtaggaagt ttctcaccaa
    98521 ttttatactc tccatttaca atttttttct ttatatctaa gtaaatttcc atatacttcg
    98581 caattttttt caatggtgac cctccaatca aaaacatatc ttcatctata ctttaacata
    98641 aataaaccga taaaatccac atcaaaatta tacacacaat aaaaaagata tatatattta
    98701 aacaaaacta tttactttaa gttgtaagcg gtgttatcat taagtggaaa caggaggtaa
    98761 aaaaattatg acaactatga aaaagctaac ttttccagat gatttttggt ggggttccgc
    98821 ttggtcagct gagcaagcag aaggaaaagg agaaacagga aaagcagaga ctatctggga
    98881 tcgctggttt aaagaacaac cttaccggtt ttatcaacga atcgattcct ctattacaac
    98941 cgatcacatc catcaatata aagaagatat agaactaatg aaaaaaactg ggcataactc
    99001 ctttcgcgtt tctatttctt gggcacgaat gtttccaaat ggcggtaccg gaaaagtaaa
    99061 tcccaaagcc atttctttct atcgaaaatt attttccgaa atgaataata acggaatcaa
    99121 agtatttgcc aacttatatc attttgacat gcctgctact cttcaagata aaggaggatg
    99181 ggaatcacgt gaagtagttg atgcttatgt tcattacgct gaaacttgtt ttaaagaatt
    99241 tggtgactta gtttgtcatt ggtttacctt caatgaacca cttgggccta ttttaggtac
    99301 ttatcttgaa gattttcatt atccaaacct cattgacttt aaacgcggag cgcaagcagc
    99361 attcttcact atacttgcac acgcaaaagc aatacaagta tttaaagaac tagctcttcc
    99421 tagtaaaata ggcgttattc taaatttgag tcctactttt cctcgtagtc aaaatcctgc
    99481 tgatgtgaaa gcagcagaaa tcgctgattt attttatacg cggagctttt tagatcctat
    99541 ggttaaaggg aatttttcta aaaagcttat cctgttatta caagaatata atcagcttcc
    99601 tgaagattat acgaaagaag atcttgtatg tatctacgaa aataccgctc aaattcttgg
    99661 actaaactat tacgagccac gtcgcgtcaa atctcgttct tctatggtgg atacatctag
    99721 tccattttta ccagagtggt ttttcgaacc acatatcatg cctggacgac gaatgaacga
    99781 ataccgggga tgggaaattt acgaaaaagg aatttatgat ttgtgcatgg atatcaagaa
    99841 ccattatgga aacatcgaag catttatctc ggagaacgga atgggcgttg cggatgaaga
    99901 acgtttcatg gatgatacag ggcaaataat tgatgattat cggattgagt atatcaaaga
    99961 tcatcttgct tacttatgga aggcaataaa tgaaggatgt aacattaagg ggtatcatct
   100021 ttggacattt attgattgct ggtcatggat caacgcctat aaaaaccgat atgggctggt
   100081 ttcactcgac cttactactc aaaaaagaac aattaaaaaa agtggcgaat tttacaagca
   100141 attaagtgat acaaatggat ttagatacga tgtagacttg ttagttgaat aatattctaa
   100201 aattccactt gaagtgaaca cattagaaaa caagaataat gagaaatacc aataacaaat
   100261 actttttctt catacttcat ttatacttgt cagtataaga gactgtgaca aatgtagtga
   100321 tcctcagaag ttaggtctgg aaatctaact tgagaagatt tttttaaact acgtccagtc
   100381 ttttttattt gtttaaaatt gaagttgaca agtcttcatt aaaaatttag aatattcaca
   100441 agtttgacga caattatgaa aatttatgtc gtgctaaagg agttttgtta ttggatgaaa
   100501 agttagatat aaaaactgcg atcaaagaca cgttacctac cgtttttggt tatatcggta
   100561 ttggacttgc atttggtatc gttgggaaag ctgccgggtt tcatccgctg gtcgtcacgt
   100621 tgatgtccct gctgatctat gctggttctg cccaatttat cacggtcagc atgcttgcta
   100681 gccatagtcc actgctctcc atcgttctct cgacctttct agtcaattcc cgaatgattc
   100741 tgatgagtat gacgattgct ccttatttca agaaaaatcg gctgcttcaa aatctgctga
   100801 ttggcacatt gctgacagat gaaagtttcg cactgggaat gaataaattg aactatactg
   100861 gacaaaagtt aaactttcgt tggatgaata cagctaattg gatttcttat ttgacgtggg
   100921 tgggttcttc tcttgttggc gcacttttag ggaattttat tactgatccg aaaaagtttg
   100981 gtttggattt cgccatcgtc gctatgttta tcgggttact ttatcttcaa gtcatttctg
   101041 atagaaacac ctctaaacga ttacagttga tcctgattgg tctcactttg attctggtat
   101101 atgtcggact gatttttatc ccaagtaact tagtgatttt agttgtaaca ctgattgggt
   101161 gcggattggg ggtgtggatc aaacatgcct tcttttgagt ttacattgct gactatttta
   101221 ggttgtactt tagcaacttg gctttctagg atcctaccat ttgtcttact gaaaaaattc
   101281 gatttgccgc aaccgttgct tgagtattta agttttgtcc cgatcgtcat tatgtctgct
   101341 ttatggttca gcagtctatt tacccaaaat atcggacatc tgccgcagat caatctcgaa
   101401 aatgctttgg cttcagttcc tacactttta gctgctattc tttcaaaaag cttattggtg
   101461 atcgtcttgg taggaattct ttccctttcg ttgattcgct tattataaat aaaaaaacaa
   101521 gagcttatgg caaattactg tcatgcgctc ttgtttttat caaagtcaaa taagaaaaaa
   101581 atcggcgtat tcttgcttat ccgttgaacg gaccactaac aacgactttt cctaatatat
   101641 gtcctgtttc tacgtctttg gttgcttgtt tcaagttctt cgcattcatc ccatctgaat
   101701 agaccttgct caatgtactg cggataatcc cttcatttgc taaagcagca atgtgcgcta
   101761 aagcttctcc ttgcgtttcg atttcatagt tatagtctgt tttagcgaac atatactccc
   101821 agtcgaagct gatagattgg tttttccaaa cacctatatc taacggctct ttgatcccta
   101881 cgatcgttcc cacatgtcca aatggtcgga caaggtgttt gatttgatca aagtagcggg
   101941 taatatcgaa taatacagcg acatactcta cttgatcgat tcctaattca cgaaaacttt
   102001 tacttaagtc gtgatgataa tcgattggat agtctacacc tgtttttttc agccattcaa
   102061 aattcttcgg acttgcagtc gcgtagactt ctaggccagc ccaatgcgct agttgattca
   102121 aaatcgaacc gacgccccca gctccgttga tcactaagat ttttttcccg cggttggcat
   102181 tttcttctgg agtcagacca aatttttcaa ataacaattc ataagcggtc aatgaggtca
   102241 acggcaaggc tgcggcttct tcatctgaaa gattttttgg tgcaagagcg acaatacgtt
   102301 cgtcaaccag ttggtattct tgattgcttc ctgctcttgt cgttgtacct gcgtaaaaaa
   102361 cgcgatcgcc gacagaaaat ttttgcactt catcacctac agcaacaact ttcccgactc
   102421 catcaaaccc taagatacgt aaagcatttc ttatcccgtt atcttggcga agtttcgtat
   102481 cgacaggatt aacagatact gcgttgactt ttaccagaag atcccgtgaa ctgggtacag
   102541 gtatctgttc tttttcatca ataaagcttt ttggatcatc gatcgacaac ccttcataaa
   102601 aaccgactac cttcattaat tccttttctg acatacgaat tcctccttag cttcatcaag
   102661 ttggagcatc catacagttt tcatttcaat atatatagta tgctatttgt tccactttta
   102721 ttcatcataa ttattctctt acttaaagta aactatttgc acttttttgg ttaaaaaaga
   102781 ggttgcgaca agacttttgt cacaacctct tttaaacggt gttcaatcaa ctgaccctcg
   102841 gtattcgctc aaaaaacgac aaaatatgag gagctatttt tgtttggctg ttcttattac
   102901 ttgatgcagg acagcttttt cacgacctct aattcacggt gttcaagcaa gaaatcattg
   102961 ttcactgaaa agcgttggat gttctttttc aaaggtgtct aagatctctc gtacttcatc
   103021 agtagatttc gtattcatca actgaactcg caagtcattt gctcctggaa atcctttgat
   103081 atagatttta aagaaacgat gtagtcctgt gatggaacgc gggatgattt ctgaataatg
   103141 atcttgcaga tctagttgca gacgaagtag tccgatcagt tctttttctg tatgttccct
   103201 cggttctttt tcaaatgcat aaggattctt gaaaatcccc cggccaatca tgatgccatc
   103261 tacgccatat ttttcggcca attcttctcc tgtctggcga tctgggatat ctccgttgat
   103321 cgtgatcagt gtttgcggag cgatttggtc acgtaaagca atgattttag ggatgacttc
   103381 ccaatgtgca tctactttac tcatctcttt acgcgtacgc aaatggacag aaagattggc
   103441 tatatcttga tgaagtaggt gactgatcca ttcttccatc tcagacattt ccgtatagcc
   103501 gatacgcgtc ttgacgctga caggcaaacc gccagcttta gccgcttcaa tcaattgtgc
   103561 cgctacttct gggcgaagga tcaagccact gccttttcca cgttctgcta cattagggac
   103621 tgggcagccc atgttgatat cgattccttg gaagcccatt tctgccatag caatgctcat
   103681 ttctctaaaa aattctggct tgtctcccca aatatgggca accatcggct gttcatcttc
   103741 tgtaaaggtc aatcttcctc gtacactgtc ttttccatct ggatgacaga aactgtctga
   103801 gtttgtaaac tcagtaaaga agacatccgg tgctgctgca tgctttacga catggcgaaa
   103861 tacaacatct gttacatctt ccattggtgc taaaacaaaa aaaggctttg gcagctcttt
   103921 ccaaaaatta gtagtcattt atttgttact ctccattcta tcaagcagtg aagtcgcaat
   103981 ctttctcaaa aacattgtca ttatactagg aaacaaaaaa agaagcaaag tgaacagctt
   104041 aaaagatgtt tctgattgag caaaaaaaga ctgtgacaaa aatcttatca caattccttt
   104101 tccggaataa atggtgttca aaagcttgca tctgcggtaa taagtccaac caaacgaaaa
   104161 ataggaggag ctatttttgt ttggctgttc ttattacttg atgcagaaca gctttttcac
   104221 aacctctcca ctaaacggtg ttcaatcagc tgaccctcgg tattagctca acaaacgaca
   104281 aaatatgagg aactattttc ccgtttgttt ctctaatact caggtcaaaa cgctgatttc
   104341 acaacctctt ttctaacttc tcaatcctct tcctttattg atcaaatacc aagtaacggc
   104401 gtacaaaaca acgatgaata gcacaagtac gatcatcgat gttgctactg gcacatcgat
   104461 tgttccaagg aatccgtaac ggaaaccgaa gatcatataa acgatcggat tgactttcga
   104521 aacagcttgc caaaatggcg gcaacataga gatggcatag aaaacgccac ctagataagt
   104581 taacggctgc aagacaaatg taggcacgat cgatacatcg tcataagact gagcaaaaat
   104641 cccgttgagc agtcctgcta acgaaaacaa gattgccgtc atcaataatg taatgatgac
   104701 catgaaccat gaatacacat gaagtggtac aaagaacaag gaaatgatcg ttacgagaga
   104761 gccgacgaga atactgcgac ccactccgcc aatcacaaag ccccaaatga tcacatgcgt
   104821 aggaacaggc gctaccaaga tttcttcgat gtttttctgg aatttttgag agaagaagga
   104881 cgaagaaacg ttggcatacg aactagtgat agcagacatc ataatcaaac caggcacgat
   104941 gaattccata tatgaaaaac cacccatgtc accgatccga ccaccgatca tttttccgaa
   105001 aataacaaag tacaaggatg tcgtgatcac aggcggaacc agtgtttgga cccagatacg
   105061 caaatagcgg ttcgtttcct tgatagctaa actttttaat gcagtaaaat aaagattaaa
   105121 catttttctc ctccgtatga ttattttctt ctgtgatttt caaaaacagt tcttctaaac
   105181 gattcgactt attcctcata gaaagaactt tgattccttg tcttgtcagc tgatcgaaga
   105241 ttccgttcac cccttgattt cgttcaactt cgacagcgat tgtctgttca tcttcaaatg
   105301 tacaagcgta tccttcaatc acaggtttgg tctcatatgg cgctaaatca aagataaatg
   105361 tttcaaattg cagtttggat agaagctctt tcatactagt attctcgatc agttcacctg
   105421 attggatgat cccgatgttg cgacaaagca tttcagcttc ttctaaataa tgcgtcgtca
   105481 aaatgatcgt tgtaccattt tcgttcaatt ctcggagaaa ctcccacatc tcgcgtctca
   105541 attcaatatc gactcctgct gttggttcat ccaagatcag caaacgtggt tcatgcatca
   105601 atgccctagc aatcatcagt cttcgcttca ttcccccgga aagcatacgt gcacggacat
   105661 ttctcttttc ccaaagattg gactgcttca aatatttttc gctgcgtttc atcgcttctt
   105721 tgcgagagac accgtagtag cctgcttgat tcacgacgat ttgctggacc gtttcaaagg
   105781 gattgaaatt gaactcttgc gggactaatc caatctgttg ctttgctcgg actagatccg
   105841 tatccagatc ataaccgaag acattcactt ttccagatgt tttattgact aaagaagtaa
   105901 tgattccgat cgttgtagac ttcccagctc catttggtcc taatagcgca tagaaatctc
   105961 cttctttcac ggaaagatcg attcctcgca atgcttcgac cccacttcca taaacctttt
   106021 tcaaattatt tatttcaagc gcatttgcca tttatttcct atctccttat agacatgatt
   106081 ctttattgta tcatggaata cagcagatga aaaaacaact tggttccagc gaaaaatcag
   106141 gttgctgggc tcaggaaaat ctcctaatga aagacatcaa tcggacgaag tcagacaacc
   106201 ttttcagaaa aaacaaatcg aagataaagg attactattc atatgtgcaa caaaaggagc
   106261 gtgagacaaa agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaag
   106321 caaaagccaa gatttttgat ccaataaata ctttcgatca cttcgcctat cccaatacat
   106381 gccactgccg cttttcatca aataacgcgg cttccgtttt tgcggtttct actaaagtct
   106441 ctgggtaatc caaaactttc agcaaggcaa tcgcatttcg ggtccttgaa ggtccttctt
   106501 ttaatttgaa atcaaaactg attccttttc cttctgttac ttgttcttca aagtggacat
   106561 tctcacaata attctttaaa atctctgtca attcgatatc atgtgtggcg acaaatgcta
   106621 aagatggata ctccgcaagc caccgaacga ctgaagcgga agaagcaatc cgttcgatcg
   106681 tatttgtccc ttttaaaatc tcatctacga agcagtagca gcgttctttg gaagccactt
   106741 ggtccaacaa acgtttgatc gatttgattt ctgaaacaaa ataactgtcg ccttcaaata
   106801 aatcatcttc gattgccatg gaagtcaaca catgtccagg ttgcagggta aactgttctg
   106861 caatcgctgt ttggatcgtc tgtgctagaa tacagctgat ggctatactt ttgacatacg
   106921 tagattttcc tgatgcattg gaacccgtga ctaatgtatt cttctgccag ttgaccggat
   106981 tcactaccgc ttcttttaac aatggatgat agatatcttt cgctgtcaca ccgccctcag
   107041 taaactctgg tcggcaagtg atgggcatat aagtacggta attcaatatt gcagcggcta
   107101 cttctaattc tcccagcaat tcccacagct tgatggcttc agttgaatgc ttttctaatt
   107161 tagtgagaac gaaatgatag gagataaatg gcagcatgaa catgatgttg acatattcaa
   107221 aaatcaactc tgcttcactc ccactcttca tacgaaatga aaaacctaat ttagggatgt
   107281 ctcttaatgg tttagtttgc tgtttcagct cttcttgaag tggtgtcggc agttttgcta
   107341 gctgattggc ggctgaaatc gttgaaacca aataactcat gctattcagc tctgtttcta
   107401 gtgtttgttt cttcactaga taatagaccg tattgaatac taacccaccg attgccaaat
   107461 agattcctag tacttgtcct aaaagaagca aacccaaacc caccagcgga agcaagccaa
   107521 gaaaaataaa taaacctacg cgtccaatct ttttactttt tccatccgct agatattgtt
   107581 ttgcaaaatt atgatctttt tttcctaaac gagcgaattg atattggatt ttttctctca
   107641 gttgaggatt ttcctgataa aaagcaatca gtttttctaa ctgctgatct tcaccaaaat
   107701 caaagctgcg taaacgttga tacaacgctt ctgaacctac actagaatag gtactgttga
   107761 ttccttcgaa tacttcgaac atatccaggt cataccaagt aagatcatcg atttcgctat
   107821 cccatgaacg gaacttcttc tccgtgagcc atgcttcctt caagctttct tctttatcaa
   107881 atctcggttg ataaggaatt ttttcccatt tgctacgaac tgtttccttt aatttcaaac
   107941 gtgaaaaaat gtctaaagca actaataaaa taacagctgc aataataatt aaaacgataa
   108001 attctctttg acccatatcc ctctccgttc ctttatttgt tagctttagt atagcactgt
   108061 tgcgctattt gaaaagaggg taaaaaaaca cctttcaaaa taaaaggtgt ttttttcttg
   108121 tatattacat atttatctct catttatcaa aattgacaaa taatcatagg gaggaattgt
   108181 tgttaattct tgtttattct ccagtgcatt gacaactgtc ccaagggaaa ggatagcctc
   108241 aggtactatt ttttcttgtt ctgttggatt agctaagcga agaacaaatc cttgttcatg
   108301 aaaataagaa ggataaatcg atgatacaat taagtcttca ggtaattcaa tcaatgaaaa
   108361 tttacgagga acatcaagtt cattttgtaa tggccaaatc ttgttatcta acctgtgaat
   108421 aaatacattc agtttctgct tttgataaga aatagattgt tctaaccgtt tttctgcctg
   108481 ttttgccact ttgaactcat taaatcttcc ttcttctaca ttaaatccaa aagtgacttt
   108541 atactcacct atctcttgag ctagcggtgt ttccatcatg acatgccctt catttgtcgt
   108601 atctcctgaa gctcgcccag gtcgccaagc aagattaggt tttccaagtt cccctgttgt
   108661 tgaaaataag gttatgatta attgattttc tatacgttca tactctttta aaccatctgc
   108721 ataaaacgta aaataatgat cattttctgc cacagagaca ctcttatcga atatttctaa
   108781 attaacaggt ttctctacca tagtttctga ccaattcgga ggaatgacat caggggtatt
   108841 ttcaataaat ccgttttgaa tttgtgcaat tgatttttca gatttatcta aaacattaat
   108901 tgctaagcgc atacgatgcg agtaaacagt attatgaatt ttgagtgtgc cttcaacgat
   108961 ttgactttct cccagactga acgatatttc ataagatatt tcttccattt cgggtttttc
   109021 agataaacga tcttttaaat ctttaggaag ttgagctttt ccgtaaacaa ctaatgtttc
   109081 ttgtaaagaa tctttatata ctttagctgt ttctaatttt agagatagtt ctgtatctcc
   109141 ttctaatggt gaataatcat acgtatcgcc atcatttgct gaatcgatca aatgaacgaa
   109201 atcaagatat tgtctatctc caactatcaa attcaattgc ccatctttaa aagaaagttt
   109261 atatttattg ttacttatct cagttttgtc tatctcgatt gctgtttcta atttttcatt
   109321 atttttctca aattcaacaa cagtgtatcc tagtgctggc acatttacat ttatttttat
   109381 gtcaagttca taataagctg gttcatcaaa atattcgaaa cctgtagcaa tcatccgata
   109441 agcatttttc cgttctggaa aataaacttc tttttcaatg atattatagg gactaccttt
   109501 gaagtgtatt ttctttgaat cagctactac atgcacgatt ttcgatccac tataattctc
   109561 agtcgttgtg ttgaaaacaa ggacttcatt cgattttagc tttaatgcat cagccatccg
   109621 ttttacaata aggttttcga ttccgtcagc tatctcatta gcttctttga ttcgatggaa
   109681 aatatcttcc gcaacattat ctgaaacaca gccaccaata ctatcatgag cctggttttg
   109741 caaaatcttt ttccataacc gacgaagtag gcctttactg atatggatac catttctttc
   109801 tgcaatcagc atgagcggct caactcgttt tagaattttt tgttccaatt taaaattttc
   109861 tattttcatt tttgttctta ctgagccaat agaacgatga acacgagagt aaaccggctg
   109921 acgaagttca cctttatatt caggtaattc ttttttgttt ctgataactt ctacataaga
   109981 aggataatct gaaataatat tgtggaattt actgtattta ttcaacttct ctacgacttg
   110041 atcaaaattt aaaatcattg acttttgatc tacacccgaa ggtactaaaa tatctttgtt
   110101 ttttccttgc atatgaagca tttcaactgc ttcatccaac ttttcttttg caaattcagg
   110161 aatatcttta attgcgtcta aggtcatcat tccagtcata taaccaaatg gaaaattcat
   110221 ggcataaaca aatttatctc ccaatccttt ccagataaaa taaggagatg gaaccatcgt
   110281 ttcaaagttt aatcctcgcc aacacatgaa attatcgatt tctacttgat gcaaaagtgt
   110341 aggcaaattc gcattgaacc caaacgtgtc aggcaaatac cctaccatca ttggatctcc
   110401 atatttaagg atcgtatcac tgattccaat cattaagttt cttaaaattg attcagcatc
   110461 cactaataag gcatctgttt gtgcatacca cggtcccacg aatagttgtc ctgttttcat
   110521 cagtcgttgg ataaccttaa gcttttgcgg attgatctcc aaatactcat cgacgattga
   110581 agtttgtcca tctaaacaaa agtttacttt agggttcctt tccaattcat ctagaacttc
   110641 agtaaagacc tgatcagaca atacgatggc atcttcattt gtaaaatacc attctctgtc
   110701 ccagtgcgtg tgttgaatta tatgtgcatt taccatatca gattctccta ctttccttct
   110761 tctactgaat ttacttgttg ttctttttta tacttgatgg attttagtgc attgaccatt
   110821 aacgctgtaa ccactccccc aataacaatt gatactaaat ataaaggtat attcgtaaca
   110881 aaaggaattg ccataaaggt tgaaagcatt gtttcttgag taacaccaaa aaatccattt
   110941 agaccacatg ctactgcagt gcccaccacg atgcttggta ttactcgtaa aggatctttc
   111001 acggcaaacg ggatcgtccc ttcagtaatc cccacaaggc ccataatcat agctgtcttt
   111061 gcattatctc gttccgattc atcataaagt tttttgttta aaattgttgc taaaaacatt
   111121 ccaaatggcg gaatagcaat tcctaataac atggctgtac taggtccaaa gcttccgctt
   111181 gaaaaagaag caaccccaaa agcatatgcg attttattga taggtcctcc catatcaaac
   111241 gccatcattc ctcctaaaat agccgacatc aaagcagcat ttgctcctga catgccttct
   111301 agccaattag tcagtcctgt tgtcattgct tgaataggcg tagctagtac ataccataat
   111361 atgattccaa caactaatgt agtaacaaaa ggaatcagca taattgattt tagactaata
   111421 acttgcatcg gtacttttac ttttttcaat gcattagcta aatagccaca agctaatcca
   111481 gcaaccattc ctccaataaa tcccatacca agattttgac acatcatccc agtgataaaa
   111541 gctggtgcta gaccgggacg gtcagcaatt gaatatgcga tataggctga aatcatcggt
   111601 acgataaact gtaatcccgt ctgaccaatc attcgcagga ctccccagaa tgtatccgtc
   111661 tggtcccaaa cacctgtgcc accaaaaatg actgcaatag aagttagtaa ccctgctgct
   111721 acgacaagcg ggatcatata ggaaacccca ctttggaaat gatttagaat ttctcttcct
   111781 tgtttcttga attccattag taactccccc acgatatatt ttttatttgt taattaatgc
   111841 aattgcttca tcaatcgtct cttcaccatc ttttactacc tctgaggtcc ctactgttaa
   111901 aatcggttta ccgtcaaagc gacctcgttc tgaaacattt gtatctactg caaatatgac
   111961 aacatctgcc tcggaaacat ccgaaattga aagtttgttt tctatcccca tagccccctg
   112021 tgtttctact ttaatatcta accctttctt cttcgcaaac ttttctaaat tagcttttgc
   112081 catataagta tgggcaatcc ctgcgataca tgctgttact gctactattt ttgtcatatg
   112141 aaattcctcc ttttaaaatg atagagcttt taccaattct tttttatttc tcgaatcttt
   112201 tattctttta acaaactcgt catccatcaa tcttccagat aattctgcta aaatacgtaa
   112261 atgattagta cctttatcag tgtcttttat tgctaacaaa aagacgagat caactggttg
   112321 atcatctaat gcgccccatt caacagaccg ctttaacttg gctacagcca ctgttgattc
   112381 aattactgct aggcttttgc catgaggaat ggcgatattt ttcccaattc ctgtggtcat
   112441 atggttttct ctgtcaaata cgtctttttg aaattgtttg tggtcagaca caaacccatt
   112501 agtctctaac aatttcgata atttttcgac tacacttttt ttatcagatg catttaaatc
   112561 tatcactata ttatttatat tgattttttc actgatcatt tataagcctt ctttcaatat
   112621 ataaactaat ttttcaaacg acgaactcgt ttttaaattt gctaataact catgattcga
   112681 agcgatttca ttgaatgttt cataaatttt attcaattca ggttttactt tttcattaag
   112741 tgcaaaaaag aaaacagaat gaacaagtgt cccatcccaa tcaattcctt ctggattaac
   112801 gtagacacag attactggct tttttataaa atctacttcg atatgcggca tagcaaaatc
   112861 attcatcgct gttgaagata gtttttctct tttgattgct ccctctagta tcccttcttt
   112921 cgcgtaattt tcttttacca attttttggt aattatattt aaaacgttca cttgattatc
   112981 ctttatttgg tgggtaaaaa agcaaaatcg tttatctaat aaatttagaa aagcatcttc
   113041 tgtttgttca tttaactgta gatactgttt tacttttctg acatctgccc ctaacatcaa
   113101 aggactaaca acaataacag gaaaatttgt attttcaatc ggaatcgtgc ttataacaag
   113161 ttcatcagtg acttttctat cttgtagttc attgatgctt agtacatctt ctatctcaac
   113221 catatctgca aaaccgttat ttattctttg ctctaataat tttgatgttc catatccgct
   113281 actacaaact aatatcactt tcgttttgtc aggtttgtaa cgatccaaaa gtgattgaat
   113341 atggagtgtt acgtaagcga tttcatcttc attaaaatgt atacagaatc tctcttcgat
   113401 ttcctctaat aaatctacac ttatcataaa tgacctttta aaagaatatt tgattttgtc
   113461 cgtataaggg ttatagatat ttactcccaa tttgagtctt ttaactgctg cattgagatg
   113521 taatactaga ttattgatca attcttcatc aggataaaat tcatttaatt taattcttac
   113581 taactcttgt agctcaacac ccatatctaa ataggaaagc ttcgtttgat ctaagtcgtg
   113641 attcatagca tttttttcaa tcgaagtaat gtgaatgtca acataagctt gttcatctat
   113701 tggcacaata attgaaaatg ctttttcaat cattttgatt aaaataagtg tattctttga
   113761 gatttcttct tcagaattat tactacgtga taagaaattg cttgtttcaa tcctttctat
   113821 cgcaatagca aggtggatag ctaaagtttg aaattcataa tctgtaaatt tcaattgtgt
   113881 cttattcatg tatcgattaa gcaattcggc tacttttttc aatatgtcct tatttaagaa
   113941 attattcgct tcaccaatga aattgatatt caagtctaag agatctgttt tactgttaga
   114001 tgctgtaaag ccaccccaat aatagttcac aacttctgac atcaaccttc ttttactttt
   114061 ttcatcagct ttgatgcgca cgccatttcg atctgaaact aaggacatcc catgcttgtt
   114121 tagtcttttt ctaacatctt tcattgtgct ttctaccgtc gacctgctca cgtataattc
   114181 gtcagcaaga ttttgaatct ttagagaatc attagtattc aataatttag caaacacata
   114241 agttagacgg tcctccggag agtctgcgat attgatttta tgactggata ataaatttcg
   114301 aagtgtttct ttttttccaa taagcgaaac gcctttttta ggttgaacca acatttgtac
   114361 atctggcatt ttttggatta tttctttcaa aattaaaata tctttgctaa ttgttttcgt
   114421 agatacatat aattgttctg ataattcttt gtaagttgtg tgctcatttt caatcaaaaa
   114481 gtatagtatt ttcatttgcc gttcgctaaa ttcgatgccc attatcttca cctcctgaat
   114541 acagcttaag tgtacaatta ttatctctat tttcatacag aagaaagttc ttgattaatg
   114601 tagaagtttc taatattctt gattatttca aatcaataaa aaagcctgca atatttatat
   114661 cacaggcttt tttctctatt aaatatatat aagataatac atttttctac tagttctcac
   114721 taatcttgta taattaaacc ctccgcaact tgacggagat ggagaagatg cccccgtcta
   114781 atctagcggt catctctcct cccattcctt ccaccaattt ttttgacagg taaagcccga
   114841 ttccgctaga ttccgtattt gtgcggctgg tattttcggt ataaaaacgc tggaagactt
   114901 tttcaacaga ggtttgcgtt cctggtttga taggattggc cactgttaat cgaatgaatg
   114961 gatcctcttt tgaaaatgtc acctttgctt gtccatctgc ataacgcaat aaattctgta
   115021 tgatattttg cagcactcgc agcaacatga gcggatctgc taatacagtt gtatttatcg
   115081 agtgttcagc gaacgctacc tcgatatttt tctcagaaaa ttgttcataa aaagagaaaa
   115141 atacttcttc cacctcttta gaaaaagaaa gcgtatggag atccatttct ttttgcttcg
   115201 tctctattcg agcaagatca taaaactgat ccgtcatact gagtaatctt gcaacagatt
   115261 gtttgatgat cgttaaatac ttctcccgtt tctccgtatc ctctacctgt tccagtaatt
   115321 gtacataacc gttaatagca gtcaaaggag ttctgagatc atgagaaagg ccgacgatcg
   115381 atagtctgat gttttcttcc atttcttgaa atgcttgtcc tttttgttca ttttcatcca
   115441 accatgtatt cagtgcatct actaggtcca ttagattctt ttctcgaaat tcgactgaaa
   115501 gacgaccacc atattcttgt cgttcagaaa gagtggcgat tttcttagtt aatctcttga
   115561 tttccctttg caggaagaaa ataaaacttc ccataaagat aacaacgaga agcaacagcc
   115621 atttaatcaa atctaaaccc cactccccac accgtatgaa tatacacagc atgtgccttt
   115681 gctagcttcc ctcgaagatt ggaaatatgc atattcactg ttttctcact atcaaaatat
   115741 ggttcttgcc aaactgtttc ataaagattt gctcgcgaaa atactttttt cggatgttct
   115801 aaaaaaagct tcagcagatc gaattctctt cctgtcaaat ggacagccac accattcaca
   115861 tttacatccc tcgactcttt gtccagtaag atttccttgt aatagatgcg ttgcgacaga
   115921 tcttttactt ggacagaagt ctgatgacga agttggatgc cgattcgtaa caaaagttct
   115981 tcgatatcaa atggtttcgt cacatagtca tccgctcctg ctgccaacaa ggaaacttta
   116041 tctctttgat cgctttttgc tgaaagaacg atgatcggaa cattcgatgt ctgtcggatt
   116101 tctgctaaca atgcttcacc tgaaagccct ggaagcatga gatctagaag gatcaaatcg
   116161 acaggatatg tgcttaacaa taattttcct tccgtacctg aataagcatc aagaagtttg
   116221 tatctctgtt caagaacctc ctccagtaag gaatgaacag cttcatcgtc ttcgataatc
   116281 aaaatagttt ccagcaggac cacctactta atgtcagatt tttggaaaat aaacattcct
   116341 agagctgatg ataccacgat tgttactaga ctgaccagaa tcattttcgg tgcttgcgaa
   116401 taagttgctt gttgcgcaaa gtccgtatac atgagccacg tttccgtaaa ccactccgtt
   116461 agaaattcca agcctttgat ttttgcgaaa acaccgggaa tgaaggccgt tcccatgata
   116521 taaagaaaag aaagaagcaa actgacactg gtacttctag tgatgaatgt caaagccact
   116581 ggaacagata atgtccctaa tgtcagcaga agcaatacag gaaatacttt tagaacataa
   116641 tttccatagt ttttgattcc ctcaacttca ccaaatccga aagcaagtgt gtaagcaagc
   116701 atggctagtc ccgtgatcaa aaccacgcca agtgttgtga tcaaaagcgt aacgagaagt
   116761 ttcgacacat aataagtcat tcgattccgt cctaaagata acgtattgcg aatcgtaccg
   116821 ttttgaaatt cttccccaat ataaaagcac gcaaatgctg cgaaagccag aagaatccat
   116881 gcagccattt tttctaccat taaaatccct gttgcaccgt tgatgactgt atccgttgct
   116941 tggtttaatt cattgccgta ttttgtatgc atataccatt cgttccaaga ataaaaaagc
   117001 ggaagtacga ccatcagtcc tagtgagacc cacattttac ggctcttcca tacttttatt
   117061 ttttcagcag ttaatagatt aaacatgtgg attgcctcca gttaattgta agaaataatc
   117121 ttccagtttt tgcccaacta ggtgaatacc atccacagga acttttgctt ctaccaatgc
   117181 ttgattgatg gctgctactt ggtcaattcc ttcaaaaagc tggataacac ggctagattg
   117241 tacaaaataa tccctataac caagagagtc gagaaccgtt actgcttgtt ccgtcgccga
   117301 agtgtcaatt tttataaatt gacgagattc ttgtgccaat tcttctttcg ataattcttt
   117361 gatcaagtgt ccttcatgca aaataccata gtgagtggcg atctgtgaca attcatctag
   117421 caagtggcta gaaagcaaga cggtgatgcc ccgttctttt accaaacgtt ggatgatttc
   117481 tcgcatttct gccatccctg ctggatccat cccattcgtc ggttcatcca aaatcaaaaa
   117541 ttctggattc gtgatcagtg catttgcaat agctaaacgc tggcgcatac ctaaagagaa
   117601 attctttgct ttctttttcc ctgtattttc caatcgcatc attttcagca ggtcttcgat
   117661 ttctctatcc gacacaccgc cgttcgctgc ttggatacgt aggttatctc ttgcagttaa
   117721 ttctggataa agagcagggg tttcaatcga ttgacccata cgtcgtcttg ctgcctgcaa
   117781 atccgtcgtt ccaaataatt cgatcgaacc ttcatcaatc gagatcaaac ccataatagt
   117841 tctcataaag gtagacttac ccgctccatt ttccccaatc aatccataga tcattccacg
   117901 tttgatttcg attgatactt tatctaatgc tttggcagca ccgtattttt tggttatacc
   117961 agttgctttc aagaccgttt catttccaaa atccatactt atccttcttt cttattgatg
   118021 agtgaagtat agttgacggg tataaagaaa gcagccagaa atgtataaag aaagtgtaaa
   118081 ttttccaatt gaatgtcaaa aaaaacaatc ggacaatacg tgtctttcct attatcaggc
   118141 agtttgttat acgcttgtat cagtttcctg attctttctt ttcgaccaaa gtcgtttctc
   118201 tgtattcctc ttcactgaaa atttttgctt ctttcagatc aagcttgagt aattttacca
   118261 gaccggttat aaggataact atagcaagac tccctcccag aaaaattaga ctgtctcgca
   118321 gacgtggttg cgttgtcttc caatcaaaga gcgcaccaaa cagtgctaat ccaagtggac
   118381 tggccaccat ggtaatcgtt gttatcgttg acataagtcg tccttgtata tgcgttggaa
   118441 cttctcgctg aagccagacc atataaaaag caaaagaaaa cattaatcct taaaaacgga
   118501 cttatgaaaa ataatacatg ccgtttggga tttacaatta gctaccaaat aagaggttat
   118561 gacaaaagac ttttcacaat cccttcttcc gaataaacgg tgttctcctg ccaactcctc
   118621 ggtcacaagt cacaatattt atcaaacatg agaagcaatt tttgtaaatt ccttcttatt
   118681 tcttgaagct gaccacttct gtcacaacct cagaagcgga taaataatat tgtttgatga
   118741 tactttatct ttttcccgtt tgtttataga tcgaatgata ttatagacca agaatcctac
   118801 ctattaacat agctaaaaac acaaaaaagg cactttccaa attgtggaaa gtgccagaaa
   118861 agttaggatt aaggtaactg cgctcagcat tgcttcgccc agtacgattc tcgtaactcg
   118921 tgaactcgaa cgataatcgc aattaacgtt ttgagaactg tgaagcttta cgggctttct
   118981 taagacctgg ttttttcttc gtatcattga ataagtttga aaaaccttga tttataaagg
   119041 ttttcccgta aatatatttt attatatttg attaaatttg aaatgtttgt gttctaaaat
   119101 gtgttctaat ttaaaggcag tatatttcgt attttagatt aaatttttag gctcattcat
   119161 tctcaaatcc attctattca gtcaataaaa attttaaaaa gactttataa acaaagatgt
   119221 tcaagcgagc atcttatttt tttgtgctta atttgaaagg agaacatttc atgtataaaa
   119281 aacaaaaaaa gaaattatgt gtattaacta ttttgagttt ggctgttcaa gcaattgttg
   119341 gagcaattgc tcctacgatt acttttgctg atgaaattac ccatccacaa acggtaaccg
   119401 tagaactaga tttagcacat caatatgctg ttgaaggaac ttttagtgat ggtcgtccaa
   119461 tgtcagaagt cactgttccg cattatgcag tgtacaacgg ctttaaacaa gatattttct
   119521 gtattgaacc aggagtcccg atttacaatg agttcactcc tggctatgag aaaaacccgt
   119581 taccagatat gtccgataaa gccaaattag tttccgtttt atggaaaaaa gtaggtacag
   119641 atgcagatac tcatattgtg gcacagaaga tgatctggca agaagttaat gggtataccc
   119701 ttcactcaat aaaacgatca gatggtagtg ccgtaaatat cgcagccatt gaggcaaaaa
   119761 taaatcaagc cattgacgat tatcagaaga aaccaacctt ccataatagt acggctaaaa
   119821 cagtattagg gcaatcgact actgtgacgg atacgaataa tctgaatttg tcagagttcg
   119881 atgaggttgt ggaaaatgcc gcaaacattg attatcgtgt gaatggtaat cagttgataa
   119941 tcaccccaaa tgccaattca aaagaaagtg gtgtgctgac gcttaagaaa tctgctggta
   120001 ccggaacacc tgtcgcctat aaaaaggctg gccaacagac tttaatggcc ggggcgattg
   120061 ataaacctaa tacctacaca atcaaaattg atgtggaaac ggagggttct ttaaagatca
   120121 aaaaagtcga taaagaatcg ggtgatgttg taccaggaac ggttttccat ttagactttg
   120181 gaaaaacttt acctgcaaaa gacgtgacta ctgacaaaga aggcattgct acattggatg
   120241 agattcctca tggtacaaaa gtaaccatta ccgaaaaatc agtaccggcg ccttatacga
   120301 ttgataccac ccccatgact accaccatta aagcaggcga aaccatttac gtgacttcaa
   120361 aaaacgcacg ggaaaaaggg caaatcattc tggataaaag cggagttgaa acagggagtg
   120421 atctttggaa tgacaattat tccttagctg gtaatacgtt tgccattcgc aaagacagtc
   120481 caaccggtga aatcgttcaa gaaatgacca cggatgaaaa cggtcatgcg gaaacaccaa
   120541 aagagattgc taatgcgttg gaattgggaa cctattatgt gaccgaaact aaagctagtc
   120601 atgggttcgt gaatacgttc aaacctgtaa aagtcgaatt gaagtatgcc aatcaaaccg
   120661 tagcccctgt taccagtaac gtaaaagggc aaaatcaaga agtcactggc gaaaccactt
   120721 tgacgaaaga agacaaagat actggggata aagcacaagg taaggcagtc tttgagggtg
   120781 ctgaatacac cttgtttact gctaaggatg gaaaagctgt taaatggagt gaggctttta
   120841 aaccagagtt agcgaaggga acgaaaggtt ctgatgaaac ggtcactttg actttagacg
   120901 aaaagaacca agttgccgtt aaacatttag ctatcaacga gtattattgc caagaaacaa
   120961 aagcgcccga aggatatagc cttgatgaaa caaagtatcc tgtatccatc aaaaaggtgg
   121021 atgatagcga aaaaaatgcc gtgattaccc gaaatgttac ggcaaaagaa caagtgattc
   121081 gctttggctt tgatttcttt aaatttgctg gatcagctgc gggcactacc gaaactggct
   121141 tcaatgatct gacctttaaa gtgtcgccat tggaagggac caatgaaatc acaggtgccg
   121201 aagatgaagc gaccacagct tataacgagc aattagggtt tgatggttat ggcaagtttg
   121261 aaaatcttcc ttatggggat tatttacttg aagaagtaga agccccagaa ggttttcaaa
   121321 agattacgcc attagaaatc cgttctactt ttaaggaaaa caaagaagac tttgtgaaga
   121381 gtgagtatgt ctttaccatt accgaacaag accaaaaaca accaattaaa acggtgaccg
   121441 ttccttacga gaagctgacg aacaaagcat tttctgttag tttgaaccgt ttaatgctct
   121501 atgatttgcc tgaggaagaa gatagtttaa cttctcttgc gacttggaaa gacggaaaca
   121561 aagaattaac ttctctggat tctaccgagc tagttgataa attgagttac aatctacatg
   121621 aaatcaaaga agactggtat gtggtagcgc aagccattga tgtggatgcg acaaaagctg
   121681 cccaagaaaa agatgaaaaa gccaaaccag tggtgattgc agaaacaagc gcaacgttgg
   121741 cgaacaaaga gaaaacagga acttggaaaa ttcagcataa attaaccgcc gaacaagttt
   121801 taaataaaac tattgtctta ttcaactatg tgtatgaaaa taaggaagct tttgaagcag
   121861 gcgataagcc agtagcgaag gatgttagct tgaataacca agcccaaact gtcagttgta
   121921 cagtggaaca ccatgtttct atccaaacaa aggcccacct agaaaacggt tctcagacct
   121981 ttactcatgg tgatgtggtg gatatgtttg atgatgtgtc gattactcat gatgtactgg
   122041 atggctcaaa agaagctttc gaaacaattc tgtatgcttt attaccggat ggtacaaaca
   122101 aagaaatttg gaaatctggc aagattgatt atgaagtaaa tgataaagaa ttcaccaaaa
   122161 ctgtgcttgc gaaaaaagta gataccggaa aatatccaga aggaaccaag tttacttttg
   122221 cggaaatcaa ttacgataaa gatgggaata tcaatggaaa acacaatgaa gatttgaaag
   122281 aaaaatctca aaccttaaca ccaaaagaag ttccaaccat actaagtacg ccgaaacaac
   122341 cggaaacacc aactgttcca agtggctctc aagaatctag tcccacagtg aagaccttcc
   122401 ctcaaaccgg ggagaaaaat tccaatgttt tactgttcat tggttttact ttgatttttg
   122461 cgacggcggg ctattatttc tggaatcgcc ggaactaagg tgatgagatg atacaagtaa
   122521 atcctaagaa ccaacgtgcg cgaccgcctc ctaaaaaagt agtcgcgcta tttttgtatc
   122581 caaaactaac aatgaaaaga ggaaaagaag atggaattga aatttgtcgt gccagatatg
   122641 gctgaaacct ttggaaagtt aagttatgcc ggtgaaggag aaattataac agaaggatat
   122701 ggacggaata ctacggtgat tggtcgcagt tatcatttgt attccagtaa gcaacgggcc
   122761 gatgatattg aggtggtagt agctgcggaa gccggtgaaa aggattttga tcaagaccaa
   122821 ccgctaaaag ccgtgaatcc ccatttggtt gccaaaggct atgagattga gaatcgtggg
   122881 tttactgatt acgtgttgta tgttgatgat ttagtgaaag cataggagga aaagaagatg
   122941 agattaacag aaggtattgt cgtagattca ggtttaacat ttgggaagtt gcgtttttcc
   123001 gcattacgcc gagaagtacg gaagcaaaat gaggatggaa caattggtaa tgaggtaaaa
   123061 gaacgaacct ataatttaaa atcctctgca caagggcgaa tgattcaagt tagtatccca
   123121 gctaatgtac ccttacgcga gtttgcttat gatgcagagg tagagttggt caatccaatc
   123181 gtggataccg ttgccaatta tgtttttcga gaaggaacta ccgttaattg gttcattaag
   123241 gcggatgatt tagtcttgaa gcggcagccg aatcaaggaa atcctacgaa ccaaaatgaa
   123301 agaaagaaat aggtgaagat tatggaaatt aatgttgaac atattttaga ttgtctcgat
   123361 caatatggaa aaggcgagct gactgaggaa caactcgtta aagcattaac ctctgatgaa
   123421 aaaatgtttc tgattataca tcaaggttta cttggagaaa atagcgacag tgaagaagac
   123481 tctgatgtac tagactggtt aggagaagaa gagtctttct ttatagttgt cgaagtaaat
   123541 gaaaacttat gtcggcaggc agaatccatt ttggaagaaa ttggtgtgga gatgccggat
   123601 gctattgaag gctttttaaa tcaattggtt gaaacgaaac aactcccctc ctcgtagcag
   123661 taaatgacta gcataacttt ttgaaattgc ctaatgaaat cctattgggc tttttcgatt
   123721 ggaggtggaa accatcaaaa tgtacaaagg acatcgcata cgcgcaggag atcagcactt
   123781 ggtttatcac tttgttcttg gctggctact cgctctgttc atcggttgga tgagcgtctt
   123841 ttattttcaa gagtttagac aatttgatat ttctaagcta tcactttcta ctattgaaat
   123901 cgtttggtct ataaaagatt tagtatgtct gcttggaagt ctcgcttttt caggagctat
   123961 gatattgctt tatattcact tttttcttga tcattggcga agcttgtggc atcgacaaaa
   124021 gctagctcgg atgattctag agaaccattg gtatgaagtg aaacaaactc aaagtgaagg
   124081 ctttttcaaa gatttgaata gtagccgaac cagagagact atcagttact tccccaaaat
   124141 ctgttatcga atgaaagatg gattactgtc tattcgcgtt caaatttcac ttgggaaata
   124201 ccaagatcag cttttaaaat tggaaaagaa gttagaaagc ggactgtatt gtgagttagt
   124261 agaaaaggaa ctcaaagact cctatgtgga gtatacttta ctgtatgata tgatcgccaa
   124321 tcgaattggg atagacgaag tagtggcaga aaatgggact ctgcgattga tgaaaaatca
   124381 agtatgggct tatgattctt taccccatat gttaatcgct ggtggcacgg gtggagggaa
   124441 gacctatttc ctcctcacca ttatcgaagc actattgaag tcagatgcag aattgtttat
   124501 cctcgatccc aaaaatgcag atttagctga tttaggtacg gtgatgcctc atgtttattc
   124561 acaaaaggaa gaaatttctg cttgtgtgga agatttctat gaacgtatga tggctcgtag
   124621 caaggcaatg aaagaaatgt ctaactacaa aacaggagag aattatgcct atcttggact
   124681 tccacccaac tttttaatct ttgatgaata cgtggcttat atggagatgt taacgacgaa
   124741 agaaagtgcg gtgattttga ataagctcaa acaaatcgtg atgttgggtc gtcaatctgg
   124801 tttctttctg attttggctt gccaaaggcc ggatgcgaaa tatttaggag acggaatccg
   124861 cgatcaattc aactttcgcg tggctttggg tcgtatgagt gaactcggat attccatgat
   124921 gtttggggag gtcgaaaaaa acttctttat gaagcacatc aaaggtcgag gttatgtgga
   124981 tacaggtggc agtgtgatta gtgagtttta tacgccactt gtaccaaaag ggtatgattt
   125041 cttagattca attagtaaat tagaaaagat gaatgattga gtgatcttca atactgactt
   125101 tatacttcaa gtaacgtata atacttttat atagtaggaa gaaaggggat aattaatatg
   125161 gaaagtaatg attcttattt agagtatgca aaagcaaata aggataagtt tatttcttat
   125221 attatcaaag ggaaatcccc cgaagttgga cgagacgcag tttttatggc agggagtcct
   125281 ggggctggaa aatcagaggt tgccattgga ttagctgaga attatgataa ccatgtgatt
   125341 attgatgcgg attactttcg cacccagttt cctgattata atggaaaaaa ctctagtctc
   125401 tttcaaaaag catcttcttg gttggtagag caggcattta gatatgtctt agatcatggc
   125461 tattctttta ttctggatgc aacttttgca atattaagtg ctgaaaaaaa tatctcgcgg
   125521 gcgttgaaaa aacattttcg agtgacgatt ttctatgttt atcaagaccc taaaatcgct
   125581 tggaaattta cacaagaacg tgaaattgca gagggacgtc atgtgccgaa aaaggcattt
   125641 attaacgctt ttttcaaatc aagagagaac attgcaaaag taaagagtaa acatccagat
   125701 gtattgcttc atatcataat aaaagattat acgaataata tttccgaagt tcattatgct
   125761 acggataatc tagaattatt tttaccacta gggtatagta ggaaagattt ggaggttcaa
   125821 ttacatgact gagaaagaac aagtaacgaa aattgtaaag aaatacaata agagcattgc
   125881 ggatttatcg gaaaatgcta ctgcaaaaga gttcaaaacg gtgattaaat atgtagccga
   125941 tcaggccaat gaaaaacaac ggaaattagt tggattaaat aaaaaatagt aggacaaatt
   126001 aataatgtat gagccaagag caaaatgttc ttggcttttt tctttgcaat gaatgaggta
   126061 atgtatgaga tttttagatt tattcgccgg tattggtggc tttcgtttag gtatggaaca
   126121 ggcgagccat cattgtatcg gtttttgtga aattgataaa tttgctagac gtagttataa
   126181 agcaattcat gatacaagta aggaggtgga aatgcatgac atcacaagtg tatcagatga
   126241 gtttattcaa tccctcggac cagtggacat cctttgcggc ggatttccgt gccaagcttt
   126301 ttcaattgcg ggaaagcggc aaagattttc cgatactcga ggtactttat tctttgaaat
   126361 cgctcggttc accactcttc tccgacctaa gcttttattc cttgagaacg tccgaggatt
   126421 gctcaatcac gaaggagggg ctacgttcga gacgatcctc cgaacgctgg atggattggg
   126481 gtatgacgtg gagtggtagg tgcttaactc aaaggcctac attccccaaa gccgggagcg
   126541 gatattcctt atcggacatt ctcgagacgc atgtaccgaa caagtatttc ctatcattgg
   126601 accgtcttca acatctgatc aaaacatcag aaatttggta aatatcaatc cttccaatcg
   126661 aggaatgggt ggacaagtct atggttcaga tggcgtagcg ccaaccttaa caggtgatga
   126721 aggaatcaaa atcgcactgc cagcaaggga tggaatctct gtagcaggac tattaccggg
   126781 aaagtttgaa caaggtaatc gagtttatga agttactgga accgccccca ccttgtcaac
   126841 gaaacaaggt ggtacaaaaa tcatgattcg aaaaaatgaa acagaatatc aagaggtgaa
   126901 gccagaagac agtgtgaatc tggcttttcc taattccaca agtcgccgag gtcgtctggg
   126961 aaaacagagt gttcatacct tactaacagg agaccaacaa gcgatcgtca cggatcagta
   127021 tcaaattcgg aagctaacac ctagagagtg ttggcgactt cagggctttc ccgattgggc
   127081 ttttgatcga gattctcaag tcaattcaga tagtcagttg tataagcaag ccggaaactc
   127141 tgtaacagtt ccggtcattt ttgatattgc cagaagatta aaagagttgg atgtacatgg
   127201 tttatgatga gttgattgga gaaatttatt gggtgattgg aaagattcag tcagacccag
   127261 aattagaaga acaattgcga cggttaaaat ttgatattcg caagaatggt gtcaaagtcg
   127321 ctggcgatcc atatttaatg aatgaggaga cggatgctcg aattgaaata aatcaagtaa
   127381 ttgcagaatt tgagcggatt gcggaccaag caaaagaacc agatattcgt caatacttgt
   127441 tagaaatgaa agcagagttg gaagtaaatg gtattacaga tgagtaacct aaaccaacac
   127501 aactgactgt taggcgctga ccgcggagga ttcgcgaagc agaaatcctc cgtggtgctg
   127561 tgcctgttca tggacggcgt tagccgacca tgatgtctca cccccgtatc taacaggggg
   127621 gtacaaaaac acaaaaaata agtaagcaac cattaagaat gcttgttgta tcaaagatag
   127681 taagtaattt gtataggtgt taactcattt gaaaaagtta acaccttgaa tttggaggtg
   127741 agaacttggc acaacggaat ttagattatc ggctattaaa agaccgacgc aacgaatacg
   127801 gcgtttcaca aaataaattg gctacggctt gtggacttag tcggccgtac ttaaatcaga
   127861 tagaaaatgg tggcgtaacc gcatctataa aaaccatgag gaaaattttt gaccaactgg
   127921 aaagctttaa tcccgatttg cctttgacgt tactgtttga ctatgtaagg attcgctttc
   127981 ccacaacgga tgcacgaaaa attattcaag aaattctcca tttgaaattt gagtatatgc
   128041 tccatgaaga ttatgccttt tactcctatc aagaacagta tgtcatgggt gatattgtgg
   128101 tgatgttgtc tcatgaagaa gataaaggtg tgcttttaga attaaagggg cgaggttgcc
   128161 gacaatttga aactttttta ctcgctcaaa agcgtagctg gtacgacttt ttcgaggatt
   128221 gtctaaaggc cggtggcgtg atgaaacgct tggacttggc aatcaatgat cgagtggggc
   128281 tattggatat acctgagcta acgaaaaaat gtcagaagga agaatgtatc tccttgtttc
   128341 gtacctttaa aagttatcgt tccggggaac ttttaaaggc tgatgaaaag gacggcatgg
   128401 gcaatacctt atatatcggc agtctcaaga gtgaggttta tttctgtttg tatgaaaaag
   128461 actatgaaca atatatcaag ttagggattc cattagacca aactgagacg aaaaatcgtt
   128521 ttgagattcg actgaaaaat gaccgtgctt ttcatgcgat tcaagatttg ttaaaaggtc
   128581 gtagcattga gagcaccacg ttttccatta tcaatcgtta cttgcgattt gcggataaag
   128641 tagaaggtaa aaggcgaacc aactggccct tgaatgaaca atgggggcgt tttattggac
   128701 ggaatcggaa agagattcaa ttaacttccg agccaaaacc gtataccatt gaacgaacct
   128761 tgaattggct aggccgacaa gtcgccccta cgtggaaaat ggctaaggag ttggatcgat
   128821 tgaatcggac aacctatatc caggatatgg tacagaatgc acgcttatca gaccgacata
   128881 aaaagatttt ggagcaacaa agtatggcaa ttgaaaattt gattatatga aaagaggaat
   128941 cgtcatggga attgtaaaag atattttttt ggtatttggt ggcagtatgc ttggtgttac
   129001 tgtgatgtgc ttgatgaatg caagtgcagc agcggatcga gcaatggaaa agaaaggaaa
   129061 gtgacaagat gaatttcgga caaaatttat gtgcgactcg ttccttagtg aaaagctaag
   129121 gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct gacaggtgga
   129181 atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt gtatgaggaa
   129241 actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag ttgatgaaca
   129301 tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt cgggggtcta
   129361 taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa tgtacgggtc
   129421 taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg tggcaaagta
   129481 agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca gcaggcttat
   129541 agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg aaaggtattg
   129601 ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta atgctgaaaa
   129661 gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct caagtcgtgt
   129721 atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata aaaaagctca
   129781 ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa acattgtgtg
   129841 tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat gatttatatg
   129901 ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta tcgagagaaa
   129961 atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca gcaggaacag
   130021 acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc aaaaaagtaa
   130081 gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg cgaaaagaaa
   130141 taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg gacaggctta
   130201 tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt agtgaaaaca
   130261 gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc tataaccgcc
   130321 tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc tttgacaacg
   130381 tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac aagcacttga
   130441 tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt acaataacat
   130501 atccagagaa aggaactccg caagggggaa taatatcccc actactagca aacattgttc
   130561 ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt acaaaaaact
   130621 atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac aaagaaatga
   130681 agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt agagttttct
   130741 gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg attgaacaac
   130801 gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga aaaagatact
   130861 ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta gttgttaaat
   130921 cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca caggcaaaga
   130981 aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt tataattcaa
   131041 tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg gattgtatga
   131101 aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac aaaaggggca
   131161 gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat ggtaaatcta
   131221 aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga tatatccaac
   131281 acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag ggaagaaaat
   131341 ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg aaattatctt
   131401 tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct gctcaacatg
   131461 gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat tgtcatcata
   131521 ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg gtaaaagagg
   131581 cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat atagctctat
   131641 tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta gctggcaatc
   131701 aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa cacgatggaa
   131761 cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt tgagatattt
   131821 ataatatcag gaacttacct atccatatat caatggtttt taaccaatgc ccaatcctta
   131881 gtcttactgg caattgtggt cattggtttg tttttaggat ttaagcggga gttttccaaa
   131941 ctgattggct ttttggtgat tgctttgatt gcggtcggat tggtctttaa tgcttctggg
   132001 gtgaaggatg tcttactcag tttgtttaac cgaattgtcg gtgcgtaagg gggaagcacg
   132061 atggaacaga tgcgtgttta tattgcgaac ctcgggaaat ataacgaagg tgaattggtg
   132121 ggggcgtggt ttaccccacc tgtcgatttt gatgaagtga aagaacgaat tgggttaaat
   132181 gacgaatacg aggaatatgc aattcatgat tatgaacttc cctttgagat tgatgagtat
   132241 acgccaattg aggaaattaa tcggttgtgt ggcttagcgg aggaacttga aggaacgcca
   132301 gttggtgaag ttgcttctga gattcaacat gctttcttca attcttttga ggagatggta
   132361 gagcatgtgg atgatattat ctattatcca gattgcgatg atatgagtga tgtagcatat
   132421 ttcttgattg tagaagctgg tgattttgga gaagtaccag aacacttgaa gacgtatatt
   132481 gattttgatg cgtgtggtag agacttggag attggaggca attatttggt aacgagtcga
   132541 ggtgtttttg agtatccata ttaacaaaat tattgaaggg tagttgattt ctaaactatc
   132601 cttcttttta aaggaatgat ttgatgaaga aaataaaaag ctacaccagt atttgggcag
   132661 ttgaaaaggt catttatgca attaatgact ttcaactgcc ttttcctgtg acttttaacc
   132721 agatggcttg gtttgtttta tccttgctgt ttgtcatcgt atttgcccat gtgcctccac
   132781 tatctatgat agagggggcc tttttaaaat acttaggtat accggtggca gttacttggt
   132841 tcatgtcgca aaaaacgttt gacggtaaga aaccattggg atttttacga tcttttatta
   132901 gctatcactt acgatttaag gtcactttcg caggaaagaa agtcaaagaa cagaagaaac
   132961 gatgggacga acccattact ctggtaagga gtgtgaacta tgtacccgat taagtatatt
   133021 gaaaataatc ttgtctttaa tcaagaggga gaatgttttg cctactatga gttaatacct
   133081 tacaattact cctttttgtc acctgaacag aaatatcaag tccacgataa ctttcgtcaa
   133141 ttgattgcgc aaaatcgtga aggcaagatt catgccttac aaattgccac agaaagtagt
   133201 attcgtgcca cgcaagaacg atcaaaaaag gaaattaccg ggcgattaac agaagtagcg
   133261 aaacaacgaa ttgatttaca gacagaggca ttagtatcca tgattggcga tagtcagatt
   133321 gattatcgct tttttattgg cttcaaactg attgcgacag atgaagaggt caatctaaag
   133381 aatctcaaga aatctttctt ctccggcttt caagaatttg tctatggagt gaatcatcat
   133441 ttgatgggcg attttgtttc cttatccaat gaagaaattc gccgatatac caagcttgaa
   133501 aaactaatgg aaagtaaatt ggctcgaaga tttaaagtca gacgagtcac accgagtgat
   133561 ctgatgtatt tgattgaaca tatctatggc gaaaagggta caccatttga agaatatgaa
   133621 tttcagctac caaagaaaaa gctgaagtcg gaaactttgg tgaaacgtta cgacttatta
   133681 cgtcccagtc gttgtttgat tgaagaaaag ccccggtact tatgcatgga acatgagaat
   133741 catgaatcat atgtagcgta cttaacaatt aatacaattg tgggggaaat ggagtttccc
   133801 tcctcagaac ttttctatta ccagcaacaa caatttacat tcccaattga cactagtatg
   133861 aatgtggaga ttgtgacgaa caaaaaggca cttgctaccg ttcgcaataa gaaaaaggaa
   133921 ttaaaagact tggacaacca tgcctatcaa tctgacaatg aaacaaattc caatgtctta
   133981 gatgcattgg attccgtaga tgaattggaa actaccttgg atcagtccaa agaatccatg
   134041 tacaaactga gctatgtggt tcgagtaagt gccgaatcag tagatgaact aaagcgccgg
   134101 tgtgatgaag tgctagattt ttatgatgat accaatgtaa aactagtccg gccttttggc
   134161 gatatgatgg ggctacatga agaattctta ccttctagta agcgatacat gaatgattat
   134221 atccagtatg ttacgtctga ttttctcgcc ggacttggtt ttggcgccac tcagatgtta
   134281 ggggagttgg aaggcattta ctttggttat aacgtagata cggggcgcaa tgtttacctg
   134341 aaaccggcat tggcctcaca aggggtcaag gattcagtta ccaatgcgct agcagcggca
   134401 ttcctcggtt cactcggtgg cggaaagtcc tttagtaaca atctcttagt ttattacgcc
   134461 gtcctttttg gtggacaagc tgtgattgtc gatccaaaag gggaacgggg tggctggaaa
   134521 gaaaccttgc cagaaattgc ggatgaaatc aatattctca acttaactag taagccaaaa
   134581 aatcaaggat tacttgatcc ttatgtgatt atggagaaaa agaaggattc tgaaagtcta
   134641 gcaattgata ttctgacctt tttaacagga atttctagtc gagatgggga gaagtttcca
   134701 gtgttgcgta aggccattcg gacggttacc caaagcaatc aacggggatt attacaagta
   134761 attaatgagc ttcgaaaaga aggctcacca gttgcggaaa atatcgcgga tcacatcgag
   134821 tcctttaccg attatgattt tgcccatttg cttttctcag atggttcgat tacccagtcg
   134881 attagtttag ataggcagtt aaatatcatt caagtagcgg atttggtttt accagatgca
   134941 gaaaccactt ttgaagaata taccaccatg gaattgctta gtgtttccat gctaatcgtc
   135001 atttccactt ttgccttgga ctttatccat agtaatcgag aaatcttcaa aattgtagac
   135061 ttagatgagg cgtggagttt tcttcaagta gcgcaaggga aaacattatc gaataagctc
   135121 gttcgtgctg ggcgggctat gaatgccggg gtttactttg tcacgcaaaa tagtgatgat
   135181 ttactggatg aacgcttgaa gaataatatc gggttgaagt ttgcgtttcg cagtaccgat
   135241 attcatgaaa tcaagaaaac cttggaattc tttggcttgg atcgagaaga tgaaagcaat
   135301 caaaaacgcc tacgagattt ggaaaatggc caatgcttga tgcaggattt gtatggtcgg
   135361 gtaggcgtgg ttcaggtaca tccagtcttt gaagaactct tccatgcctt tgatacccgt
   135421 ccacctgttc aagagagaat ggagtgaggg gatgaaaaag aaactttttc ggattgtggg
   135481 aatcgttttt attagcatac tcactctgat agttctattg agtttagttg gtacggtagc
   135541 cgaggcgaca gggctagttg atgatacagt tgaagcagga aatctatatt ccaaatattc
   135601 actgaacaac tatcaactag atttctttgt ggatagctct tgggattggt tgccttggaa
   135661 ttggggtgat ggcttaggga aaagcgtgat gtatggtctt tatgccatta ctaatttcat
   135721 ttggacggtg agtttgtatt tgtcgaacgc cacgggttat gtggttcaag aggcttacaa
   135781 attagatttc atttcggata cggctgaaag tattggaaag aatatccaaa cattggctgg
   135841 tattactgaa aatggactcc agacctccgg attttatttt gggtttctat tattgatgat
   135901 tttagctctg ggggtgtatg tggcgtatac cggattatta aaacgagaaa ccacgaaagc
   135961 agttcgagcc gtgattaatt ttgtgatgat ttttctacta tcgggttcgt tcattgctta
   136021 tgcgcctacc tatatcacaa aaatcaatga ctttagctca gatgttagtg aagcggccct
   136081 tacccttgga accgagatcg ttgtacccaa ttcagaaagc caaggaaaag atagtgtgga
   136141 tttgattcgg gatagtttgt tttcgattca agtccaacaa ccttggttac tactgcaatt
   136201 tgatgattcc aacatagaag aaattggtga agaccgggtc aacaagattc tatctgtgag
   136261 tccagatgaa aacaaaggca aagatcggga agaagcggtc aaggcagaga ttgaagacaa
   136321 tgacaatgcg aatctcagta ttaccaagac catgaaccgt ttagggaccg tggtcttttt
   136381 ggtattgttc aatattggca tttccttctt tgtttttctt ctaacaggga ttatgttgtt
   136441 ctcgcaaatt ctcttcatta tctttgcgat gtttctgcca attagtttct tattgtccat
   136501 gttgccgact tatgaaagtt taggaaagaa ggcgattatt cgtttattca atacgattat
   136561 gatgcgagcg ggtgttactt tggtgattac gactgcattt agcatctcca cgatgttttt
   136621 caatatttcg gcaacctatc catttttcat ggttgctttt ctgcaaattg tgacctttgc
   136681 cggtatctat ttcaaattgg gcgacattat gagtatgttc aacctccaga gtaatgatag
   136741 ccagtcaatg ggaagacgcg tcatgcgaaa accgcaaatg ttaatgaatc gaaaattgcg
   136801 gcaactcaat cgaaatgtgg gacgagcttt ggcttttggt ggtggtgcag cagtcggaaa
   136861 taagttggca aaggaacaat caaaatccaa atttaagcca tccggttctt ctctacgaaa
   136921 gaattcacga ttaccgaacg atcacgaaat actatctgac ttaactaagg agaatccagt
   136981 ttcaaataat aagaaacaat cccgaatgaa tttggctggg agaaaaatcg gcaaagtttt
   137041 ggatacccaa gctttggtga aagataagac taaacaagta aaggatcagg taaggaatac
   137101 gccaacgaat ttgaaataca atctccataa aggaatcgaa aagtcgaaaa aagcaccaga
   137161 agaattcaag cgcggactgt tccaagaaaa agcggatcga gtggatttgc gagaaaaaca
   137221 acgacaacga agaaatgcga aaatggacga aaaacgcaag atactgagtg aagcaacaaa
   137281 tcgtcaggga aaaagaaggg cgaatattcc aatagataaa gcagctcaac ctcagaaaga
   137341 tatgatgctg aaaaaagaag caccaaagcg gattgtgaga gcaaatctga atcccgaaat
   137401 caaacgaaaa ctaactagtc aagaaatcat ttcaaaaggg aaaagccaat cagcaagtaa
   137461 gaaaaattct ttccaacaag tgaaacagag gtccactctg ccaaagcaga ccaatcaaaa
   137521 agtacaaaaa agaatgaacc atcgtccaaa atcaaggtca ggtgagaaaa aatgaacttg
   137581 aagaaagtgg gtgttatttc attaactttt ctgaccatct cttttatggg tattttgatg
   137641 tgtgtgggtt tgttgtttgg tgaagacagt gagggaaatg gtagttctgg cacttctcct
   137701 ggcggaacta gtgtctcaga agaagtattg aaacaccgtg caatggtgga aaagtatgcc
   137761 aaagaatcgg atataacaga gtatattcca attcttttgg cgattattca agtggaatct
   137821 ggtggcacaa tggaagacgt tatgcaaagt tctgagtcag ccggattacc acctaattca
   137881 ttaagtaccg aggcatccat caaacaaggc tgtctctatt ttgcgtcttt ggttaagcgt
   137941 tccaaagaac tagggtgtga tcaagatagt attattcagg cctataacta tggtggcggg
   138001 tatctagatc atgtcgggaa aaacgggaag aagcatagtt ttgctttagc tgaatctttt
   138061 tcaaaggaaa aatcaggtgg tcaaaaagtc gattacccca acccaatcgc gattaaggaa
   138121 aatggtgggt ggcggtataa ttatggcaat atgttttact gtttattagt gaagcaatac
   138181 ctaactacaa ctcagtttga tgacaaaata gtccaagaaa tttttgatga ggcatttaag
   138241 tatgaaggaa cggcctatgt gtttggtggc tcaagtccag aaacggggtt tgattgtagt
   138301 ggcttgaccc aatggtgtta tgccaaagtt gacctgaaac ttcctcgggt ggctcaggat
   138361 caatatgatg ccatgactca tattgatcta aaagatgcca aaccaggtga tttagttttc
   138421 tttcattcaa cctatgatgc cggtacttat gtgacccatg tgggcattta cgcaggggag
   138481 aatcgcatgt ttcatgcagg agatccagtg gggtggacga atctaacgga aaactattgg
   138541 cggcagcatc ttatcggagc tggccgatac aaataagaga aaagaggaaa aagaatgaag
   138601 ataaaaattg aacggaatca aaaggaaaag agcccaaaaa agaaaaaaga acgagttgta
   138661 tccgtgggta agcatcgaaa aatggtgctt gccctttggc ttttattgtc ttgtagtctt
   138721 gcttttggcg tttataaaaa tttcaccgcc attgatcaac atacaactca tgaaaaagtg
   138781 gttataaaag agaaggtagt gaatacttct ggcgttgaaa gttttacaga ggattttgcg
   138841 aaagaatatt tttcatggaa aaataacaaa gaagcaattg aaaagagaat gagtaatctc
   138901 gaacagtacc ttacagaaaa cggtctcgct ttaatccaag atatggttcg agcagatatt
   138961 cccacgagtt ccgaagttca atctgtaaaa attctagatg ttgaaaaaca ctcggaagaa
   139021 tttgtcgttt catttttagt ggagcaacat attacagagg gaaaaaagac gcaatcaatt
   139081 tcttctgcat atcgagtgac aatctttgaa gatgaaaaca ggaatcattt agtaactagt
   139141 ttgccaacaa tgattggaaa gccagacaag gcaaaatatg aagcaaaaca agtagaaaac
   139201 gattcagaaa ttgatgccaa aacaacggaa gaaatcaccg attttttaga aacatttttt
   139261 aaactttatc catcagcttc tgaaaaagaa ttggagtatt atgttgaaaa tggtgcgatg
   139321 cgaccaatca atattgactt aaagttttcg gagttagaga atccagttta tctacaaaac
   139381 ggaaaaaatt ttctagtgag tacaaagata aaataccttg ataatgtatc aaaaaccact
   139441 agctactttc agtacaaatt agtattacaa aaaaatggaa actggaaaat cgttgatgtt
   139501 aaataataat gactcaatct aattttatta gaagttataa gtagtgtaac ttatttcagg
   139561 cagaagtcgc ccatcctcta taggtgggtg atgaatgcca ttcggtaact cgaaaaccga
   139621 caattaagac atagtgcctt tttattttaa tccatgtcat aatcagtcta tataggaaat
   139681 ggttgatata ccatggaatt agatacaaat aatcattcag tttttcttct tggttacccc
   139741 cttattttag tagtgaaaca ttgtaaacat gtcattgatg atgtaatgtc agcttatgca
   139801 aaaactgcct ttgaaagaat ttcagaatca catcacatta ccttagatga atgaaatcgt
   139861 gataaagaat actttcatat tatgctcaaa gcacaaccta aaaccgaatt aacaaaattc
   139921 agcaatgcct aagctcacgt ctgataaaat gagactttct aagggtcaaa aatttccttt
   139981 gaatacgatt attgcttaga taaaagtaaa agccttagaa ctacggggat agcttggtta
   140041 ataagagata tcgttgttag taaagacata ggcttgcaag tatgctctat tcccaagaat
   140101 ctcccccttc aagcaccaag gatcgttaaa ttcagctaag tggcaagtaa ttcactagac
   140161 gataattatc tccatatttc aatctcagct tttccatttt tcatagcaaa ttccgttatt
   140221 tttatagcat ctaaaagatt cagcttttcc actgatcttt caccactttt cagctttttt
   140281 attgtgctta aattgatacc agtacctttt gatattgaat tggaagtaaa atcattaagg
   140341 gtttttttta ttaaattcat atccgcaatt ccagcgttca taagaatgaa gattctcctc
   140401 tcatagacta ctttgaaaat ggtactacag tggctgttta tatatttcag taggttactg
   140461 tagtggtcat cttattataa ttagaaaagg aacctaaatc aaaaatgcta aagaaaattt
   140521 tcatagtatt aagcctctca tgactaaagc cacggaattc ttgataaaag agtatacttg
   140581 caagcctaaa cagcggtatc tcttattaac caagctatcc ccgttgttcc taaggttctt
   140641 gatgttttct aaggcaatgc ttgtattcat agcccttggt caaaatattg atactatcgt
   140701 tgacgtttcg attatgatgt atacggcaaa taggacaagt ccattctcga attgtgagtg
   140761 acttcttacc atctgtgtgt ctacattctg aaccaatttg actagacgga aatcatttat
   140821 ctatcttaat gattttttga cagaagtatc gaaaatcttt acataatctg ggtgatgtat
   140881 tcttatgcag atgagagcgt tggctccgta ttcataacca gtagcctcta aaacgtagtc
   140941 catcggtggg atacctagct tgcggttgcc agcggctttc gcagtcttct tgtgatcaaa
   141001 tcaagcatct cattgagcac tagtattttg aagataatac ttgagttttt cggcttttag
   141061 aagttcactt catcttccat catccatgga aatcccactc acccatacgc aggcctccaa
   141121 aaattcttca acagtggttt tttcagacat ttttctgaat acctccttgt tttttgatac
   141181 gccagatagt caggaaaaag gcaacaaaac acaaaacaaa gctgcctaaa aaggtaatct
   141241 tcattccata taaaaagaca tccggccgat ttgcgatata gttagttact tgctggccca
   141301 tcttagcaga catcgcttga tataagaccg tcgtagaaag cgaaatcccg ctgaccatcc
   141361 ccaaatttcg ggcaaaggaa ttcatcgagc ctgccagtcc caagttttcg atagtgaccg
   141421 agctcataac catcgtatta ttgggggact ggaacaaggc attgccggca cccatgatgg
   141481 cagtagcgac aatgtatagc cacaaaggag agtccactga caaaaacata tacatgacct
   141541 gggttaccga caataagccc aagcctacta ataccaaaat ctccgggcca acccggtcgg
   141601 tcaggtagcc gcttaaaggc gccccgacga ccatcatcaa aggaaagacc atcatcaaca
   141661 gcccagcata gctaggactc aacccgcgag cattttgcag ataaaaagga atcactacat
   141721 tgacaaagaa gttggaagaa aaaatcaaca aggctgtaat caagctcatg gtaaaaatct
   141781 tgttcttaaa aataccgaaa gaaatcaatg gagaggctgc tttcttttca acttttaaaa
   141841 agctgacaaa ggcaatcact gaaattacga acagtacaag ggggactgga tggaaaaagc
   141901 cactttcttg ccccaaaaag attgctccaa aaaagctgat aatcgtagcc gcaatggcag
   141961 caaagccccc tccatcgatt gtatggccgc tcatggtgat atcttttggt aagaattttt
   142021 cagcaatcaa catcgttacg attcccaccg gtacattgat ccaaaaaatg tacgcccaag
   142081 aaaattggga caaaatcaag ccgccaagac ctggtccagc aatcgagcct aatgaaacaa
   142141 acgcacctat tgctcccaat gcccgaccac gttcatgtat gggaaagact tccgtgatga
   142201 ttccggcatt tgtagccata gtcatactag caccaatggc ttgtaccacc cgtgcgaaca
   142261 ataaaatacc tagcgaatga ttgaacccac acaacagcga tcccaagaca aagatcagcg
   142321 taccaatccg aaatactttg attttcccac ggctatcgcc aattttacca aacagcaaca
   142381 aacaagaaca gacaatcatc agataaacgg acactaccca ttccgcttga ttcattggta
   142441 tgcccatatc atctgagatg gtaggtagtg caatattgac aatactgcca tccaatgtgg
   142501 acatgaaggt aaacatagat atagcaatca aaatccacca gcgatttttt tggacttttg
   142561 catcttcttg ataactatac ataataggat ttcctttcta atgatcgtgt agctaagaac
   142621 aatataacct atgtctactg cccaacaact tctcgcgact ctagccatag gaagcttgag
   142681 taatttcgat ttgatatcct catgtaacca tgtaagttgg agatgcttta tttgaactta
   142741 ctctatagta actagtgata attcgcttta ctttcttcta gcaatttcta aaagtcgact
   142801 tcattgttct tcagattaat agtgtgagct atctcgtgag acgtaagcaa atttccattc
   142861 tactttttcc caattttttc atatttatgg tgttgcacct atttgttttc caatttgctt
   142921 ttcaaataca ttgctatgat attcaattcc ataggattat actaaatatc aatagtatga
   142981 ataatatatt atagatgttt atatatcact gttaattatt atccacaata attaatgatt
   143041 acctcgatat ttgtcaatca aaggttgaaa caatttattt tcagcatctt ttctagcttg
   143101 agctgcactc ttaatagaat catacgatcc taaatagtac ctcttttttt ttaaagttat
   143161 atacgcaatc tatttctctt tagaacgata aactccctta acaccacttg tattattttt
   143221 cggtaatttt gacgttagac actctattac tgtcccttca acacatgtcc ttgtttcttg
   143281 cctttttaaa catccacaac tttgagtatg tccaaaaaat aagttactat aacttatctc
   143341 acacatactg ccacactcac aatgacaaac ccattttgtt ttccatgaac agttattgtc
   143401 caaaggatac tttgcagtaa gtaatccgaa ttttttattt tcaatgtgat gcttttttga
   143461 tttcaaacat ccacagcttt ttacatcacc ttttagaagt cgctttgccg atactaactt
   143521 ttttctccca cacagacatt gacattccca aacaacagtt ccttcacttc gcagtttagt
   143581 tggcttgatt gcaactaact taccaaaagt tttatttgtc aaatttttat atttatgcct
   143641 atttttataa tttccacatc cacaactttt ggttctacct gttagtaagt ttgatcgata
   143701 tacaatcgtt tcattcccac agtcacatag gcaacgatat tttttatatc cattatgagt
   143761 aatctcctca acaacagtaa ggtgaccata tctttccttc actgcaccta ccctcccaag
   143821 aaagaagtac catataattt caattaactt ttaataaatc agaaaaaaat atttccaatt
   143881 tttcttagtc tgattttatg actaatttac aatacaagac tgaacgatac gtacacgaaa
   143941 tcctcaagat agataaattg ttttcatcta gtgaaacctg ctcaaaatat gagcataaag
   144001 acggcaataa tacactcgat attcgataat ggacttgttt tatttgtcaa acccatcgta
   144061 atcgagatat caattccagt ctcaatatcc tgatcaaagg tctaagaatc caaccatttt
   144121 cttgttactt tgtcagattg attacctttt ttagtctccg aataataagg ttttcggatc
   144181 aactaacatg ctctgagaaa gactactatc tttgcaaatt tccaaatgaa ggtgtgggcc
   144241 agtactattc ccagtacttc ctacatagcc aattatttgt ccttgcaaaa cattatctcc
   144301 agtttttact aggtattgtt gctggtgagc atataacgcg gttgatccat cttcgtgttg
   144361 tatcaccacg taatttcccc aagagtagtg aaactctgct ttaacaacct taccagcttt
   144421 aactgcatga atcggctcac cctgtgtagc tgccatatca agtcctcggt gaaattcatt
   144481 tccacgattt ccaaacaaac tggttattga ataattatga ataggcactt ggtatccagt
   144541 cttactcatt tgtggacctt taacttcttt atcatagttg gttaaatcgt aggttttaat
   144601 taattcattt agcttcaaat agtattgtgt atctgttgca taccgtcctg taaggaattt
   144661 agttgcttct cgatatgttt tactattagc ttttaatgct cctgcataaa aatctttatt
   144721 tccactaatt cccttagtta ataatttggc ataatcttca aagctttcct catagttttc
   144781 atacactcta aattttgatt gggtcgtata aagcgttcca ttacccaaat cttcgtttgt
   144841 taccataatg acaaagtttc cattataagt tccttttatc ccaaataaat tgtaattcgg
   144901 tgcctgagct aactggcttt gaccactggc agattctaag atcgcttgtg caatcataac
   144961 agaagcatat aaatcatatt tctgaccaat ttttctcgca gactcaccaa ttttcataat
   145021 aaaattttct acagattcat ttttgtcaaa atgaatttct tcattaccag atagtattgg
   145081 ttgtgattgg aaagattctg ttgattctat ttgctgtggt gtcgaaaaag tttttgtttg
   145141 tccttccgtt tttggcgctt ccttttttga agattctata tggtttggtt ttgtcacttt
   145201 cgaagaagtt atttcacttg tactacttga agttgttgaa gattcggtac ttgaaatcgt
   145261 actactttca cttgacgaag ttgttgaaga ctcggcattt gaagtcgtac tactttcact
   145321 tgatgaagtt gttgaagact cggcatttga agtcgtacta ctttcacttg atgaagttgt
   145381 tgaagactcg gcatttgaag tcgtactact ttcacttgat gaagttgtca aaagttcact
   145441 actctctgct gttacatcgg aattactcat ttcagtcgtc tcggttcttt cttttgcaat
   145501 tttgtatgtt gaattttcgc ttgccaacac atggaaaggt gttgctataa ggagttggga
   145561 cattaatata actgctgatg caagttttaa agattttttc atttgattta cctctctttt
   145621 ttctctttaa tagtgttttc tattaaaaat tatgataaat attttcaatg aattgagtaa
   145681 tacagtatat ttcttgattt catttagtaa cgattatgtt tcaatgttta atcctgttac
   145741 tgcctttaa
//
LOCUS       DAXLPY010000002        94097 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.002, whole genome shotgun sequence.
ACCESSION   DAXLPY010000002 DAXLPY010000000
VERSION     DAXLPY010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 94097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.002"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(29..727)
                     /locus_tag="ACF3UF_000134"
     CDS             complement(29..727)
                     /locus_tag="ACF3UF_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFD3670297.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(720..2072)
                     /locus_tag="ACF3UF_000135"
     CDS             complement(720..2072)
                     /locus_tag="ACF3UF_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFD3670298.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2295..3695)
                     /locus_tag="ACF3UF_000136"
     CDS             complement(2295..3695)
                     /locus_tag="ACF3UF_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFD3670299.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3856..4593
                     /locus_tag="ACF3UF_000137"
     CDS             3856..4593
                     /locus_tag="ACF3UF_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFD3670300.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4718..5197
                     /locus_tag="ACF3UF_000138"
     CDS             4718..5197
                     /locus_tag="ACF3UF_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFD3670301.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5194..5961
                     /locus_tag="ACF3UF_000139"
     CDS             5194..5961
                     /locus_tag="ACF3UF_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFD3670302.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6191..6760
                     /gene="lepB"
                     /locus_tag="ACF3UF_000140"
     CDS             6191..6760
                     /gene="lepB"
                     /locus_tag="ACF3UF_000140"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD3670303.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6864..7466)
                     /locus_tag="ACF3UF_000141"
     CDS             complement(6864..7466)
                     /locus_tag="ACF3UF_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFD3670304.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7572..7802
                     /locus_tag="ACF3UF_000142"
     CDS             7572..7802
                     /locus_tag="ACF3UF_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670305.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            7793..8041
                     /locus_tag="ACF3UF_000143"
     CDS             7793..8041
                     /locus_tag="ACF3UF_000143"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3670306.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            8147..8731
                     /locus_tag="ACF3UF_000144"
     CDS             8147..8731
                     /locus_tag="ACF3UF_000144"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFD3670307.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8734..9807
                     /gene="prfA"
                     /locus_tag="ACF3UF_000145"
     CDS             8734..9807
                     /gene="prfA"
                     /locus_tag="ACF3UF_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFD3670308.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9800..10639
                     /gene="prmC"
                     /locus_tag="ACF3UF_000146"
     CDS             9800..10639
                     /gene="prmC"
                     /locus_tag="ACF3UF_000146"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFD3670309.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10632..10811
                     /locus_tag="ACF3UF_000147"
     CDS             10632..10811
                     /locus_tag="ACF3UF_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670310.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10833..11858
                     /locus_tag="ACF3UF_000148"
     CDS             10833..11858
                     /locus_tag="ACF3UF_000148"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFD3670311.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12033..13277
                     /gene="glyA"
                     /locus_tag="ACF3UF_000149"
     CDS             12033..13277
                     /gene="glyA"
                     /locus_tag="ACF3UF_000149"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFD3670312.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13430..14377
                     /locus_tag="ACF3UF_000150"
     CDS             13430..14377
                     /locus_tag="ACF3UF_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFD3670313.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14511..15140
                     /gene="upp"
                     /locus_tag="ACF3UF_000151"
     CDS             14511..15140
                     /gene="upp"
                     /locus_tag="ACF3UF_000151"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFD3670314.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15279..15521)
                     /locus_tag="ACF3UF_000152"
     CDS             complement(15279..15521)
                     /locus_tag="ACF3UF_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670315.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15642..15714
                     /locus_tag="ACF3UF_000153"
     tRNA            15642..15714
                     /locus_tag="ACF3UF_000153"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15675..15677,aa:Thr,seq:cgt)
     gene            complement(15833..16471)
                     /locus_tag="ACF3UF_000154"
     CDS             complement(15833..16471)
                     /locus_tag="ACF3UF_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFD3670316.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16594..17226)
                     /locus_tag="ACF3UF_000155"
     CDS             complement(16594..17226)
                     /locus_tag="ACF3UF_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFD3670317.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17577..17876
                     /locus_tag="ACF3UF_000156"
     CDS             17577..17876
                     /locus_tag="ACF3UF_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD3670318.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18371..20536
                     /gene="acm"
                     /locus_tag="ACF3UF_000157"
     CDS             18371..20536
                     /gene="acm"
                     /locus_tag="ACF3UF_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFD3670319.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(20808..21293)
                     /locus_tag="ACF3UF_000158"
     CDS             complement(20808..21293)
                     /locus_tag="ACF3UF_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFD3670320.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    21383..21728
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            21773..22414
                     /locus_tag="ACF3UF_000159"
     CDS             21773..22414
                     /locus_tag="ACF3UF_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3670321.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            22433..23068
                     /locus_tag="ACF3UF_000160"
     CDS             22433..23068
                     /locus_tag="ACF3UF_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3670322.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            23086..23901
                     /locus_tag="ACF3UF_000161"
     CDS             23086..23901
                     /locus_tag="ACF3UF_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3670323.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            24220..25656
                     /locus_tag="ACF3UF_000162"
     CDS             24220..25656
                     /locus_tag="ACF3UF_000162"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3670324.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            25845..28292
                     /locus_tag="ACF3UF_000163"
     CDS             25845..28292
                     /locus_tag="ACF3UF_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFD3670325.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            28522..29589
                     /gene="rlmN"
                     /locus_tag="ACF3UF_000164"
     CDS             28522..29589
                     /gene="rlmN"
                     /locus_tag="ACF3UF_000164"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFD3670326.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            29579..29785
                     /locus_tag="ACF3UF_000165"
     CDS             29579..29785
                     /locus_tag="ACF3UF_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670327.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(29782..30885)
                     /locus_tag="ACF3UF_000166"
     CDS             complement(29782..30885)
                     /locus_tag="ACF3UF_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFD3670328.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            31438..31986
                     /gene="aac(6')"
                     /locus_tag="ACF3UF_000167"
     CDS             31438..31986
                     /gene="aac(6')"
                     /locus_tag="ACF3UF_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFD3670329.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            complement(32234..32353)
                     /locus_tag="ACF3UF_000168"
     CDS             complement(32234..32353)
                     /locus_tag="ACF3UF_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFD3670330.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            32532..34193
                     /locus_tag="ACF3UF_000169"
     CDS             32532..34193
                     /locus_tag="ACF3UF_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3670331.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(34263..34610)
                     /locus_tag="ACF3UF_000170"
     CDS             complement(34263..34610)
                     /locus_tag="ACF3UF_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFD3670332.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            34694..35635
                     /gene="opp3b"
                     /locus_tag="ACF3UF_000171"
     CDS             34694..35635
                     /gene="opp3b"
                     /locus_tag="ACF3UF_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFD3670333.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            35636..36679
                     /locus_tag="ACF3UF_000172"
     CDS             35636..36679
                     /locus_tag="ACF3UF_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3670334.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            36685..37755
                     /locus_tag="ACF3UF_000173"
     CDS             36685..37755
                     /locus_tag="ACF3UF_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670335.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            37745..38698
                     /locus_tag="ACF3UF_000174"
     CDS             37745..38698
                     /locus_tag="ACF3UF_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670336.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            38710..39720
                     /locus_tag="ACF3UF_000175"
     CDS             38710..39720
                     /locus_tag="ACF3UF_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFD3670337.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(40005..40826)
                     /locus_tag="ACF3UF_000176"
     CDS             complement(40005..40826)
                     /locus_tag="ACF3UF_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFD3670338.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(40923..41201)
                     /locus_tag="ACF3UF_000177"
     CDS             complement(40923..41201)
                     /locus_tag="ACF3UF_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670339.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            41469..43478
                     /gene="metG"
                     /locus_tag="ACF3UF_000178"
     CDS             41469..43478
                     /gene="metG"
                     /locus_tag="ACF3UF_000178"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFD3670340.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(43957..44544)
                     /locus_tag="ACF3UF_000179"
     CDS             complement(43957..44544)
                     /locus_tag="ACF3UF_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670341.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            44719..46041
                     /locus_tag="ACF3UF_000180"
     CDS             44719..46041
                     /locus_tag="ACF3UF_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3670342.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            46196..46972
                     /locus_tag="ACF3UF_000181"
     CDS             46196..46972
                     /locus_tag="ACF3UF_000181"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFD3670343.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            46965..47534
                     /gene="rnmV"
                     /locus_tag="ACF3UF_000182"
     CDS             46965..47534
                     /gene="rnmV"
                     /locus_tag="ACF3UF_000182"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFD3670344.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            47527..48411
                     /gene="rsmA"
                     /locus_tag="ACF3UF_000183"
     CDS             47527..48411
                     /gene="rsmA"
                     /locus_tag="ACF3UF_000183"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFD3670345.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            48862..49491
                     /locus_tag="ACF3UF_000184"
     CDS             48862..49491
                     /locus_tag="ACF3UF_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670346.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(49615..50724)
                     /locus_tag="ACF3UF_000185"
     CDS             complement(49615..50724)
                     /locus_tag="ACF3UF_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670347.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            50933..51355
                     /gene="mgsA"
                     /locus_tag="ACF3UF_000186"
     CDS             50933..51355
                     /gene="mgsA"
                     /locus_tag="ACF3UF_000186"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFD3670348.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      51542..51640
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            51678..52214
                     /locus_tag="ACF3UF_000187"
     CDS             51678..52214
                     /locus_tag="ACF3UF_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFD3670349.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(52254..54017)
                     /locus_tag="ACF3UF_000188"
     CDS             complement(52254..54017)
                     /locus_tag="ACF3UF_000188"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670350.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(54020..55735)
                     /locus_tag="ACF3UF_000189"
     CDS             complement(54020..55735)
                     /locus_tag="ACF3UF_000189"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670351.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(56514..56738)
                     /locus_tag="ACF3UF_000190"
     CDS             complement(56514..56738)
                     /locus_tag="ACF3UF_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670352.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            56929..59706
                     /locus_tag="ACF3UF_000191"
     CDS             56929..59706
                     /locus_tag="ACF3UF_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3670353.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            59787..60206
                     /locus_tag="ACF3UF_000192"
     CDS             59787..60206
                     /locus_tag="ACF3UF_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3670354.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            60218..60688
                     /locus_tag="ACF3UF_000193"
     CDS             60218..60688
                     /locus_tag="ACF3UF_000193"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3670355.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            60705..61484
                     /locus_tag="ACF3UF_000194"
     CDS             60705..61484
                     /locus_tag="ACF3UF_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3670356.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            61471..62292
                     /locus_tag="ACF3UF_000195"
     CDS             61471..62292
                     /locus_tag="ACF3UF_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3670357.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            62309..63358
                     /locus_tag="ACF3UF_000196"
     CDS             62309..63358
                     /locus_tag="ACF3UF_000196"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3670358.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            63371..64375
                     /locus_tag="ACF3UF_000197"
     CDS             63371..64375
                     /locus_tag="ACF3UF_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3670359.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            65008..66027
                     /locus_tag="ACF3UF_000198"
     CDS             65008..66027
                     /locus_tag="ACF3UF_000198"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFD3670360.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            66070..66951
                     /gene="galU"
                     /locus_tag="ACF3UF_000199"
     CDS             66070..66951
                     /gene="galU"
                     /locus_tag="ACF3UF_000199"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFD3670361.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            67251..67628
                     /locus_tag="ACF3UF_000200"
     CDS             67251..67628
                     /locus_tag="ACF3UF_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670362.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            68234..68848
                     /locus_tag="ACF3UF_000201"
     CDS             68234..68848
                     /locus_tag="ACF3UF_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3670363.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            69621..71360
                     /gene="yfcC"
                     /locus_tag="ACF3UF_000202"
     CDS             69621..71360
                     /gene="yfcC"
                     /locus_tag="ACF3UF_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFD3670364.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            71517..72701
                     /gene="iadA"
                     /locus_tag="ACF3UF_000203"
     CDS             71517..72701
                     /gene="iadA"
                     /locus_tag="ACF3UF_000203"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFD3670365.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            72812..73015
                     /locus_tag="ACF3UF_000204"
     CDS             72812..73015
                     /locus_tag="ACF3UF_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFD3670366.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(73116..73778)
                     /locus_tag="ACF3UF_000205"
     CDS             complement(73116..73778)
                     /locus_tag="ACF3UF_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670367.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(73791..75293)
                     /locus_tag="ACF3UF_000206"
     CDS             complement(73791..75293)
                     /locus_tag="ACF3UF_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3670368.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVTVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            75841..77520
                     /locus_tag="ACF3UF_000207"
     CDS             75841..77520
                     /locus_tag="ACF3UF_000207"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFD3670369.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            77647..78126
                     /locus_tag="ACF3UF_000208"
     CDS             77647..78126
                     /locus_tag="ACF3UF_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFD3670370.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            78345..79025
                     /locus_tag="ACF3UF_000209"
     CDS             78345..79025
                     /locus_tag="ACF3UF_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFD3670371.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            79033..80364
                     /locus_tag="ACF3UF_000210"
     CDS             79033..80364
                     /locus_tag="ACF3UF_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFD3670372.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            80379..81341
                     /locus_tag="ACF3UF_000211"
     CDS             80379..81341
                     /locus_tag="ACF3UF_000211"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFD3670373.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            81452..81790
                     /locus_tag="ACF3UF_000212"
     CDS             81452..81790
                     /locus_tag="ACF3UF_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFD3670374.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            81869..82576
                     /locus_tag="ACF3UF_000213"
     CDS             81869..82576
                     /locus_tag="ACF3UF_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFD3670375.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(82679..84160)
                     /locus_tag="ACF3UF_000214"
     CDS             complement(82679..84160)
                     /locus_tag="ACF3UF_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3670376.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            84469..85005
                     /locus_tag="ACF3UF_000215"
     CDS             84469..85005
                     /locus_tag="ACF3UF_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3670377.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            85083..86453
                     /locus_tag="ACF3UF_000216"
     CDS             85083..86453
                     /locus_tag="ACF3UF_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFD3670378.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            86520..86855
                     /locus_tag="ACF3UF_000217"
     CDS             86520..86855
                     /locus_tag="ACF3UF_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670379.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(86936..87793)
                     /locus_tag="ACF3UF_000218"
     CDS             complement(86936..87793)
                     /locus_tag="ACF3UF_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3670380.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            87900..88415
                     /gene="tadA"
                     /locus_tag="ACF3UF_000219"
     CDS             87900..88415
                     /gene="tadA"
                     /locus_tag="ACF3UF_000219"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFD3670381.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            88438..88522
                     /gene="ffs"
                     /locus_tag="ACF3UF_000220"
     ncRNA           88438..88522
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACF3UF_000220"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            88732..90117
                     /locus_tag="ACF3UF_000221"
     CDS             88732..90117
                     /locus_tag="ACF3UF_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFD3670382.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            90154..90831
                     /locus_tag="ACF3UF_000222"
     CDS             90154..90831
                     /locus_tag="ACF3UF_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFD3670383.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            90839..91603
                     /locus_tag="ACF3UF_000223"
     CDS             90839..91603
                     /locus_tag="ACF3UF_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFD3670384.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            91605..92264
                     /locus_tag="ACF3UF_000224"
     CDS             91605..92264
                     /locus_tag="ACF3UF_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFD3670385.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(92294..92803)
                     /locus_tag="ACF3UF_000225"
     CDS             complement(92294..92803)
                     /locus_tag="ACF3UF_000225"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFD3670386.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(92915..93913)
                     /locus_tag="ACF3UF_000226"
     CDS             complement(92915..93913)
                     /locus_tag="ACF3UF_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3670387.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
BASE COUNT        31254 a        16163 c        19337 g        27343 t
ORIGIN      
        1 ttttgtcaca ttcccctttt tcgaataact aggctgtttg tccttcaaga tagggcagat
       61 ccaattcttt accgtaacgt tgttctaaag ctaggcggat caaacgagct gccaggttct
      121 catttcttgc aaggataggt ccatggaaat aagaaccgaa gacatttcgg taaatgacac
      181 cttcagattg gtcttcacca ttatttcctt gaccttgtac cactttcccc aaaggtcgtt
      241 caccttcacc taagaaagtc cgaccattgt ggttttcaaa tccataataa gtttcattga
      301 attcttcgtt atggataacg atatcaccga taaaccggtt attttcctga cttaacgtgt
      361 agtgatccag tgcactgatt ccttggatct tttctccatt agctcccatg tagtagtgac
      421 ctagcaattg gtagccacca caaatggcta acatgacgcc atcattttcg atatagttga
      481 tcaaagaatc tttctttttc tggatgtctt ttgaaatgat taattgctca aagtcttgac
      541 caccgccaaa gaaaaccaag tcatatttat cagcatcaaa aggttcatgt atactaacga
      601 tctccgtatg gcaagaaacc cccatttttt ctgctatata tttcaacatc aaaaggtttc
      661 cgttatcacc atatgtgttc atcaaatttc cataaaggtg ggcgatattg agttcataat
      721 tagccacggt tcattcctcc tttgataaat ccttgagcag ctagttcttt acgaagctgc
      781 aatacagcag tgtaagtagc taaaatatag acatgctcag ttggcaattc tttgattttt
      841 tcgattactt ctggtaattc ttttgtttct gtcaatttat tttctggaat cccggcaact
      901 tttagacgta aagtcatatc tgtatgacgg tctcctccag aaataacagc tgggatatcc
      961 atatcggcaa agttttcaaa attaccatcc caaatccagc tgacatcgat tccgtctgcg
     1021 taattggcat ttaataaagc cactaaagaa aatggataag gagctagacc aatcatatcg
     1081 attacttgat tgatacctac aggatttttg acaagtacta atgtacattt tttcccattg
     1141 atattgatga cttcttgtcg gccgaatact ttctcgtcat atcctaaacc ttgtttgatt
     1201 ttatcaggat cgacattgaa gtactctgcc actgcagtag ctgctaaagc attgtagaca
     1261 ttatacatac cgccaacttc gattccgtat tcatgaccat cgatcacgaa atctgctgac
     1321 acattgtcca tccgtaccat atcagttaat cgataatcca attcaggacg tttgaagtca
     1381 caatttggac agtaatattt ccctaagttt gcataagtga tcattttata atgcaagatg
     1441 tgatgacaat ttggacataa gacaccgtct gtattgtaat gagccatttg ttcacgatct
     1501 tcttcatggt caaagccata atattttcta ggattgactg tttcgataga attgaagatt
     1561 ggtgaatcac cgttactgat aatcgttgca tttggtgact ttgcggcacc gtctacaatc
     1621 attttatagg tcgtatagat ttctccatac cgatccattt gatcacggaa aatatttgta
     1681 aataagaaca gttctggttt catatattct gtgactttgc tcaaacttgc ttcatctatt
     1741 tctaggacag caaacttttt ctgtcctttt tttggttttg cctgcaagaa agtcgataca
     1801 attccctgta ccatattcgc accagtaggg ttggttagaa cttcatcgaa ttgctggcgc
     1861 aaaatattga ctgttaaagc ggtagtcaat gttttaccgt ttgttccggt gacaacgacg
     1921 acttggtagt cttttgccaa actatctagt atatgtggat cgactttcag cgctagttta
     1981 cctggtaaac ttgatccgcc tttaaaaaaa gtttttaatg cccattgcga cgtttttcca
     2041 actgcaatcg caaaatgact gcgtattccc attatgtaac ctccaaaaac gatttgctga
     2101 cgaataaatt caactaatca taccatatgt tgaaaaaaag gttaaattgc ttttcttatt
     2161 cttaagaaaa ggttacggct gaaagtgcat gaaatcggac aaaatcgcat gatttaacaa
     2221 aaaaacagct tgaaacaaaa tgattgtttc aagctgctgt gattttatta ttccctctta
     2281 cctatattcc cattttaacc gataataatt ttctcgcttg gatattcata gcctagatct
     2341 cgtgtttctt ttggcacgaa taacatcaat gtatatagca ttccgatccg cccaataaac
     2401 atcagtgtag caatcgtgat tttgcccaca acagacaagt ctccggtaat ccctaaagat
     2461 aaaccagttg ttccaaacgc agaagttact tcgatgatga tcgagatcag cgtttgttct
     2521 tctgtagcag ataaaaaaac gatacaaaag aaacacatac caagagaaag cataaagaca
     2581 acgactgatt ttcgcacatc atcttgatcg attctccgtc caaaaatatt gatgttatct
     2641 tcacttttga ggaaggaata tagatacaaa ccgatgattg ctacagtagt tgttcgaatc
     2701 ccgccgccta cagaactagg actgcatccg ataaacatca gtaaagaaaa aatgatcagt
     2761 gttgtgattt gaaaatcacc caaatcgtga atctgcagac cagcattacg agtcgtaatc
     2821 gaataaaaca tcgaattgat ccatttgaca ctcatattgg aatcttggaa taaatggtcc
     2881 ttttccaata gataaatcaa gacagttccc gaaacaaaca agataacaaa agctaacaca
     2941 gctaatttgg taaacaagga aaaacgaaac ggaagcttcg cattggaacg tttgtataat
     3001 agccattccc ggcactccat caatacagga aaaccaattc ctccgacaaa aatcaaaaac
     3061 atgatcagga tcaagaaaaa atagtcatgt gcaaagggct tgatggaatc cccagtgacg
     3121 tcaaacccag agttcgtgac agccgatatc gcctgataaa aaccgtaaaa aacggcatca
     3181 cgccaacgat caaaatagcc tctgtaataa aaataaatag aaaagaatgt cccaaaaagt
     3241 aattgaaacc agattaaaat agcaaaagtg atccgaatca gtcggacgat accagacaaa
     3301 cgcggttgat tcatatccgt catgatcagc tgtcgctgtt tcagtgtgat ccgtcgttta
     3361 gaaaaaatga caaaagcagt agaaatcatc atgatcccca aaccaccaac ttgaaataat
     3421 atttccagca gtataatacc gttatcattg aacacagaat tgatatcaaa agtcgatagt
     3481 ccagtcacac tcactgtact gattgccatg aacagcatgt ccacaaaaga aacatggcta
     3541 tctggttcgc gaaaaatcgg catataaaat agaacgagtg ataagaccgt catcaatata
     3601 taataaaaaa cgatgatttg gatcgatgag aaatgattgg cagcaaactt ctgtcctcgc
     3661 cgctgcagcc ttcgaaagaa taaatcaaca tgcacagtac tatcctcctg acaatagtcg
     3721 tttctaccag tatacaaggg gaattaggaa tactcaaaga aattatcaaa cagataacaa
     3781 tacagctttc gattaaaata gaaatggctt ataataagga aaatcctaga aaaaagaagg
     3841 aggaggaata acaaattgat taatgctcaa caaatcgtag aaaaaatgaa aaatcaaaaa
     3901 ataaattatg atacagttct gaaaaaaatg atcatgcaat gggagaaaga agaagtaaag
     3961 cctaagatat taatacatac atgctgtgct ccttgcagta cgcacacatt ggaattcatg
     4021 tctcaatatg cagagatcac gttatttttt tcaaattcga atattcatcc taaaagtgag
     4081 tatttgcgaa gattacatga acaaaaacga tttgtagacc aatttaatga gaaaactgac
     4141 catcatgttg cgctaatcgt tgatgaatac cgtccaaatg aattcaccaa aatggtttta
     4201 acaaaccatc ttgaaaacga aaaagaaggt ggtgctcgct gcagtgcatg cttcaatatg
     4261 cgattagatc ttgttgcgca aaaagcgcaa gaactaggat acgattactt tggaagtgcc
     4321 ctgaccatct cgccaaagaa aaatgcagct ttgatcaatc agatcggaat ggatatccaa
     4381 aagatttacg ggacacaata cttgccaagt gatttcaaga aaaacaaagg ctatgaacgc
     4441 tctttgcaaa tgtgcaaaga gtatgatatt tatcgccaat gttattgtgg ttgcgtgttc
     4501 gctgccaagc agcaaggatg cgatctgaaa gaaatcaatc gggaagcaaa agcttactta
     4561 aaaacatcaa ccgtagtttt tgaggaaaat taaagaaatc tttcggaaaa acgtaagaaa
     4621 aaaataaaga atttatggta gaaataaggt agactgtata atttgtccgt agtaaagtaa
     4681 ggaaacaaga ataaatttca atgaaggaag agataagatg cgaaaagtag cacctatttt
     4741 gaagccaatc gctgtattaa caatctcgac gattgtcgcg actactacag gtattgtgaa
     4801 tagttccagc taccgtgcac caagttcaag ttctagtact gtagaagaaa caacaccaac
     4861 tacttcagtc tcgacatctg aaccaacaac aacggaaagt ttgaatgaaa ccactacgac
     4921 aagtacatgg gacgatacaa caactagttc gtcgtatgat gagacatata caactgacag
     4981 ctcaagcgaa acaagtaata cggtaccaga tggcactcca tcggattcaa ccaatccaag
     5041 tacaagtccg gatacaagtg ctagctccga aacgatacca agcagtacga ctgtagatga
     5101 taacacgcaa aatgatgatg cagcacgtac agcacagcaa aaccaagatt caggaaatac
     5161 ccaaacgtat aaccagcaag caggtgattc tcaatgacat ttttactaga ccttatcaac
     5221 ggggtgcata aattccttgg ctatttagac atcagtccta aatatcttaa ccgtggatat
     5281 acgattttaa gtgtgattcc cacgctttat ttattgagaa ttgtttatgg actttggcaa
     5341 aaccaaaact atcttcaatt tttcttatat ggacttgcat ttctagtgct tgtttatttt
     5401 actgttttaa atgtatttta ttacttttta gataaaaaca cgaaagccga tgtcactcag
     5461 ctttttgtga agtatttacc tgatgaagcg ttcaacatcc agacagaaga atcgatagat
     5521 aatggaaatt cgatcgataa agtgaataca caagaggtca tggtttctta tgacgaagat
     5581 tatcaattga aattagccga gaatatgcgg tatttgattg gaaatggtga gatcaaaaca
     5641 aatgaactcg gtcgcatgga tggatttctg gtcgatagaa atacattgta tccttattac
     5701 tatgtcaaga aaacaggaga gaaagagtat gttctaaata ttggacgaag ctactcggac
     5761 atggaaaaag tagggaccat tcgacttgac tcaacagaag acacattgga acctgtcgga
     5821 ttgttcatcg tcggcggtga ttttgtcaaa gacgggttac gctatcatga gccttatcgt
     5881 ctgaaattga ttgcaaaaaa ggcacagtcg caggaagaac cagtggttta tagtcgtagc
     5941 caaagaagaa gacattcata atgtgatgaa acgccgtgta tcagtggttg cgataaaaac
     6001 gtttattcgg aataaggggg atgtgacacg tcttttgtca cgttcctttt ttatataacg
     6061 agaaagataa gacgaacaca tcacttattc tttcctttca tttataaaca ttgtagaata
     6121 aagaaagtac aacgaagtat tgtgaaaaaa cgtaataaat aacgaggaaa atacaagtag
     6181 gaggtaagct gtgaaagaat ttttgaaaaa ttgggggatt ttgatccttg tattagcggc
     6241 tattttatta gctagagtgt acgtgtttac accagttact gtaaacgggc attcgatgga
     6301 ccctacatta agtgatggac aacgattgat ttcatctaag atctcaaact atgaacgaat
     6361 ggatattatt actacaaagg aaccggggga tgaagaacgg atgattgtta aacggatcat
     6421 cggtatgcct ggagatacag tcaagatgga aaatgaccag ttgaccatta atggcaaaaa
     6481 gtatgatgaa ccttatctgg atgagttcaa aaaagaattt tcagaagata agttacaagg
     6541 agaatatgct tatagctcag gattccaagc acaagcagaa agttcatcca cctttacgag
     6601 tgactttgaa tatactgtgc caaaaggaaa gtatcttgtt ctaggcgata accgcttgat
     6661 ttcaaaagac agccgaatgt ttgggttagt cgacaaagat atgatccaag gaaaagttgt
     6721 tttccgttat tggcctcttt cagaaattaa aatcatgtga tgaaaaaata aaaagaagct
     6781 gtgacatgtt ttttgtcaca gcttcttttt ccgaaaattc cttcttattt cttggagttg
     6841 ctcacttttt ttgcaatctc attttaagct ttttggctga tggataagaa aagcgaagcg
     6901 tttttgttca taaatagctt ttccccacga tggaaggtat gactagtagc agagacaaag
     6961 cccgtttttt ccaatcgatt attcaattct tcttggctaa agccattatg gactttcgga
     7021 tgactaattt gttcattctt gtcaaagtct acgatgatca attgaccgcc aggagctaaa
     7081 atttcataaa gttttgtaag aatattctcc gtatcaggaa tgtgtaaaag tacaagtgat
     7141 agaaggatga gattagcttg gacagcagga aattcgacag aagcatcagc gtggatcgtt
     7201 cggacatttt tcagatctgc tgcttggatc ttttcttctg ccattttcag catagtttct
     7261 gaagcatcgg caatgatcag ttctttgaat ctttccgcaa gcggtaaact aacaagccca
     7321 gttccgcctc cgtaatccag caggactttt tggtggctgt cgcgcggtag ataagtagtt
     7381 agttcttcgc gaataatctt ggctaatgct tgacggtcag gggaatcata atggttagcg
     7441 atggaatcaa aaatattttt tgtcatcaaa tagctcctta cgtaaaactt tgaaatttta
     7501 acttattata gcacgtgaaa agaaagaaag catgctatac tcaattcaaa aagggagaat
     7561 ctagaaagaa tatgccgata tcgtttgtaa aagatagaga ggaaaaagga aagtgtgtcc
     7621 gagaaatatt actagacttg cctgagtggt ttgggcttcc tgaatcaacg gaaaaatata
     7681 tcgaggaatc aagtaaacta cctttatggt gtgaaaaaag aaaagaagaa tatttaggct
     7741 ttatcactct ttcacagaca agtgaagata ctgccgaaat ctattctatt gtatgggaat
     7801 aaaaaaagac tatcatcacc aaggattagg aacaaaactt tttaaagaag cagaaggtta
     7861 cgcagcaaaa cattacaaat atttgcaagt gaagactgta gacgaggggc actactctat
     7921 atatgatcaa actatttgtt tctacgaatc attaggattt tcaaggttgg aagtttttcc
     7981 aaatttatgg gatgaatgga acccatgttt agttcttgtc aaaaaattgg aacaaaagtg
     8041 agcaatagat ttaatactaa tctgtgcttg atgaaaattc tcactgtaaa aaatgctgaa
     8101 aatcaagtat aataccatag gaacaaactg gaaggtgaaa aagagcatgg cacaactatt
     8161 ttttaagtat ggcgcaatga atagcggcaa gacgatcgag atcctaaaag tcgcacataa
     8221 ttatgaagaa caaaataagc cagttgtctt aatgacaagc ggtattgata caagagatgg
     8281 tttaggcgtt gtttcaagcc gaatcggact gaaacgtaat gcgatgccga tatttgaaga
     8341 aacagacgta tttgacgtaa ttcagaaaat ggaaagcaaa ccctattgtg tgctgatcga
     8401 tgaagcgcaa ttcttaaaaa agaaacatgt cattgctttt acgagaattg tggacgaatt
     8461 ggatattccg gttatggcat ttggtttgaa aaatgatttt cgaaacgagt tatttgaagg
     8521 atcaaaatat ttattgcttt atgcagacaa aatcgaagaa atgaaaacaa tctgttggtt
     8581 ctgccacaaa aaagcaatca tgaatttaca ttatattgat ggaaaccctg tttatgaagg
     8641 cgatcaagtg caaattggcg gaaatgaagc ttattacccc gtttgtcgaa aacattactt
     8701 tcacccatca atgattacag aaggagaata agcatgtacg atcaattaca agcaattgaa
     8761 gaccgttatg aagagcttgg agaactttta agtgacccag aagtgatttc tgatacaaag
     8821 cgttttatgc agctttcaaa agaagaagca aacacgcgcg aaacagtcga agtttatcgt
     8881 cgttataaag aagtagtaca aggaatcacc gatacagaag aactgcttgg tgaaaaactg
     8941 gatgatgaaa tggctgaact agcaaaagaa gaattatctg aattaaaaaa agaaaaagaa
     9001 gtcttagaag aaaaaatcaa gatcttgctt ttaccaaaag atccaaatga cgataaaaat
     9061 atcatcatgg aaatccgtgg agcagcaggc ggagacgaag cagcattatt cgctggcgat
     9121 cttttcaata tgtaccaaaa gtatgctgaa gcacaaggct ggaaaacaga agtgatggaa
     9181 gctaacgtta ccggaatcgg tggatataaa gaagtgatca tgatgatcac cggagacaac
     9241 gtatattcga aattaaaata tgaaagtggt gcgcaccgcg tccagcgtgt tccttcaact
     9301 gaatcgcaag ggcgtatcca tacttccacc gcaacagttg tcgtgatgcc agaagctgaa
     9361 gaagtagaga tcgatattga agacaaagat atccgtacag atatctatca tgcttcaggt
     9421 gctggcggac agcacgtcaa taaaacagca tctgctgtac gtttgactca cttaccaaca
     9481 gggatcgttg ttgctatgca agatgaacgt tctcaaatca agaaccgtga aaaagcaatg
     9541 aaaatcttgc gtgctcgtgt gtacgataag atccagcaag aagcacaaag cgagtatgat
     9601 gccaatcgaa aatcagcagt cggaactggg gatcgttcag aacggatccg gacgtataat
     9661 ttcccgcaaa atcgtgtgac tgatcatcgt atcggattaa ctatccaaaa attagatcag
     9721 attttagcag ggaaattaga tgagatcgtt gatgcattga tcatgtatga tcaaacatca
     9781 aaactggaag ctatgcaaaa tgggtaaaat gacctatcga gaagtcctgt cacgggcttc
     9841 ttctttttta gaggatcatg ggaaagaagc atatagtatc caatttttat ttttggaacg
     9901 aaaacaatgg aaaaaacttg attggctcct tcatatgaac gaagagattt cagaagaaga
     9961 acagcggttg atcgaaaccg atctgcgact tctgcttgca gatcatccac ctcagtattt
    10021 gctaggatat gcagattttt atgatcatcg gttaaaggta actgaagcaa cactgatccc
    10081 tcgaccagaa acagaggagt tagtcgaatg gtgtttagac gagacgcctg gtgtaccgtt
    10141 agaagtgata gatattggga cagggactgg agcaattgct attagtttga aagcagcaag
    10201 aaaaaattgg catatatctg ctgtggatct ttcagaagaa gcattagaag tagcgaaaga
    10261 aaatgctcag aaagaaggaa cgaaaatcag tttttatcat ggagatacat taggaccagt
    10321 aatggatcag caatttgatg tgattatttc taatccgccg tacatcagtc ggaatgaatg
    10381 ggaactgatg gatgaaagtg tccggtcatt cgaacctaaa atggcccttt ttgctgagaa
    10441 cgatggatta gctatttatg aaaaaatagc agttgaagca ccaagcgtac taaaatcaaa
    10501 tggaaagatt tttttagaaa tcggatttcg ccaaggtgaa gcagtaaaaa aaatatttca
    10561 gcaagcattt ccagataaaa aagtggcgat aaaaaaggat ctttttggca atgaacgaat
    10621 gatccaagtt tatggttgaa gttgtggatg aaaaattttt tatttgtttt tttattataa
    10681 aaaaacactt atttgacaag gatgtaaacg actttttggt ttatcaacaa gtttatccac
    10741 tattgacaaa tagattatcc acaaacagtg gaaaacttga ggataaactc agacaaaata
    10801 agaatgtatg aaaaaggggt tgtggataaa ctgtggaaac gaaacgatat gatgaaacag
    10861 aattgcaaga ggcagccgaa gcactgaaag aaggagaact tgttgctttt cctaccgaaa
    10921 cagtatacgg attgggcgcc aacgctcttt taccaaacgc tgtcaagaaa gtgttttctg
    10981 taaaagggag accgcaagat aatccattaa tcgtccatgt cgcctctttt gaacaagtaa
    11041 aagagtatgt ggacaacttt catccggcag cagagaagat tgtgaagaac ttctggcctg
    11101 gaccattaac tttgatattt aagatcaaaa aagacacttt gccctcagtt gtgacgggag
    11161 gattatccac agctgcattt cgtataccgg ataacaaaaa aacactagaa gtaatcgaac
    11221 tttccggtgt tccgcttgtc ggtccaagtg caaatacgtc gggaaaacca agtccaacga
    11281 ctgcagatca tgtatatcat gatctacaag gaaaaattac cgggattatt gatgatggag
    11341 ctacgcgaat tggtgtagaa tccactgttc ttgatttaag tgatccaaca gccatgccta
    11401 tgattttacg accaggtgca gtaacgaaag aacaaatcga agcagtcatc gaatctcctg
    11461 ttgctattga tcagcatctt gtaaaagaaa atgaaacacc aaaagcccct gggatgaaat
    11521 acaaacacta ctcacccgat acacgtgttc tgatggtcag agatggcgat tggtcaactg
    11581 cagttcaatg ggcaaaaaat aagaagatcc gtgcaggtgt catagcaagc cccgaaattg
    11641 cggatcaagt gcggacagat actgcagctg tttatatgta taacgacaac tcagtagaag
    11701 cggcggctaa aggattgttt gcaggtctaa gaggattaga tgaaccaaca cttggattag
    11761 atttgatttt tgtacaagtg tatccagaaa ctggattggg gaatgcttac atgaatcgct
    11821 tgaaaaaagc agcaggacaa aattattttg aaaaatgatc aattggttat tgtcgcattc
    11881 ttttagtatg atacaatgct atcaagtaaa tcttctatca gtgaacgaaa aactaagcgt
    11941 aactaatcgt aatagaagag atacgaatat ttggcaattt gtttttgatg ggaaaaataa
    12001 aattgtagga aaataaaaag gagctgttgt ttgtggtaga ttacaaaacg tttgaccctg
    12061 atctttgggc tgcgatcgcc aaagaagaag aaagacaaga acataatttg gagctgattg
    12121 cctctgaaaa ctttgtctcc gaagcagtga tggctgcaca aggaagtatc ttgacaaata
    12181 aatacgcaga aggttatcca gggcatcgct attatggtgg gtgtgaattt gtcgatatcg
    12241 ttgaaaattt agcgattgac cgtgcaaaag aattattcgg agcgaaattt gcgaacgtcc
    12301 agcctcactc cggctctcaa gccaacacgg ctgcttatct cgctttggta gaaccagggg
    12361 acacgatctt aggaatggat ctttccgcag gcggacatct aacacatgga tcaccagtca
    12421 acttcagtgg caaaacctat cactttgttg cttacggtgt tgatccgaca acagaagtta
    12481 ttgattataa tgtggtacgt attttagcta gaaaacatca accaaaattg atcgtagcag
    12541 gtgccagtgc ttacggacga acgatcgact ttgcgaaatt cagagaaatc gcagatgaag
    12601 taggcgcaaa actgatggta gatatggcac atatcgcagg attagtagca gcaggacttc
    12661 atcctaatcc agttccttat gcagatatca caacgactac cactcataaa acattgcgtg
    12721 gccctcgagg cggcatgatt ttgacaaacg atgaagcatt agcaaaaaaa ataaatagtg
    12781 cggtatttcc tggtattcaa ggcggccctc tagagcatgt gattgcgggt aaagcagtag
    12841 cattcaaaga agcattagat cctgcattta aagaatatag tgaacaaatc atcgccaatg
    12901 caaaagcaat ggtcaaagtt ttcaatcaag caattggaac cagagtcatt tcaggggcga
    12961 cagataatca tctgatgttg atcgatgttc gcgagttagg tataaatgga aaagaagcag
    13021 agagcatttt ggacagtgtg aatatcactg taaataaaaa ctcgattcct tttgaaacac
    13081 taagtccatt caaaacaagc ggtattcgaa tcggcacgcc agcaatcact actcgcgggt
    13141 tcaaagaaga agatgctgta aaagtggctg aactagttgt caaagcatta caagcaaaag
    13201 atgataacgc tcaactagac gaagtcaaaa caggtgtacg cgaattaact gaaaaatttc
    13261 cgttgcataa aaaataaaaa tttaaattcc attagtaaac agaaaagttc aatgttgggc
    13321 ttttctgttt attttttggg aaaacggatt ctttgacaat atcggtgatg ctctctagta
    13381 tatgaggtgt aattttagtc ttcacactaa atctcaggga ggaaaagtca tgactgatcg
    13441 tatctcgtta gaaaaggaag cagtagcatt cagtgatgca aatgcgcctc atccgcgtat
    13501 ctatgaacta gcaccggaag aaggaagagt tttactagaa gaagtacaag aatcacctgt
    13561 gaacaaatat tccgtcgata ttgaagactt gatggtggat actggcgaat ggggaaaact
    13621 caatattcgt ctcgtacgac cagaagggaa tatggataaa ttaccagtta ttttttatat
    13681 tcatggagca ggctgggttt ttggcagtgc tcaaacccat gataaattga tcagagaact
    13741 tgcggttcgt acgaattccg tcgttgtctt tccagaatat agtcgatcac cagaagcaaa
    13801 atatccaaca gcaattgaac aaaattatgc tgtgttgcaa cagctgaata aattagccaa
    13861 gtcaaaaaat ctggatctcg agaatctaat cgttgcagga gattcagtag gtggtaacat
    13921 ggctacagtc atgacgatct taacaaaaga acgaaagggc ctcccaatat ccaagcaatt
    13981 gctgtattat ccagtcacaa acgctgattt tgatacagat tcctatcatg aattcggaga
    14041 aaactatttt ttgacaagag aaggaatgat gtggttttgg gaccaatata cgacgaatga
    14101 agaagagcgt gctgaaatca cagcttcgcc tttgagagca aatataaatg aactaaatga
    14161 tcttccttca gcaatgattt taacgggaga agcggatgta ttaagagatg aaggtgaggc
    14221 ttatgcgcgc aaacttcgtg atgcaggggt tcctgttaca caagtacgct tccaaggaat
    14281 catccatgat tttgtcatgg taaatgctat ggatcagaca aaggcaacgc gtgcagcaat
    14341 ggcattatct acttcttgga tcaagaaaaa agaataagct ttgcttgtcc gcaggaaaac
    14401 ttcttttcaa aaacggattt tcttaggaaa aatggcgagt ttgactagtc aatcacttga
    14461 ttttgtttta caattaaaaa gaaacgacag aacaaaggag agcttaaaaa atgggcaaat
    14521 ttcaagtgat cgatcatcca ttgattcaac acaaactaac tattattcgg gacaaaaact
    14581 gcggaacaaa ggtttttcgt gaagtagtcg atgaaatcgc tatgttgatg gcatatgaag
    14641 tatcacggga tatgccattg gaagacatcg tgatcgaaac accgatcact gaaacaacac
    14701 aaaaaacgtt gtctggtaaa aaagtagcga ttattccaat cttgcgcgca ggtattggaa
    14761 tggttgacgg tatcttggaa ttgattccag ctgctaaagt gggacatatc ggtctttatc
    14821 gagatgaaga aacattggaa ccacatgaat atttcgtcaa acttccagaa gacattgatg
    14881 cacgtcagtt gtttgtagta gatccaatgt tggcaacagg cggatcagca atcatggcaa
    14941 tcgatgcatt gaaagaacgt ggcgcgtcga acattaaatt tgtttgtttg gtagcagcac
    15001 ctgagggagt aaaagctttg caagaagcgc atcctgatat tgacatctat acagcttctc
    15061 tagatgaaaa attgaatgaa catggttata tcgttcctgg actaggggat gcgggtgacc
    15121 gtttgtttgg tacaaaataa gtaaatacga aaaagggtgt gacacaactt ttgtcacatc
    15181 cttttttggt catttttaac gtttgatgca gaacagcttt ttcacagctt tcgtttgcat
    15241 ataaaaaaac catcccaaaa atgcagagat ggtcaaattc aaatcttttt tagttctttg
    15301 tagttaacga ttactacacc cttactttgc gtcatcaagt tcgcattttc tgcagtttca
    15361 tcaatctcaa caacagcgga atttttcaat tgctttgaaa tcgttccagt ttgcgacttg
    15421 ccgtgaattg tgaacattac gtgagtattg atcttgaatt tttcaccaat ttccgatggt
    15481 acgatagttg tatcaaattt tccaaaagtt gccattttca taaaacctgc ctttcacatc
    15541 aattatacca cgttttatga aaaatatcat gaaattaaac taattttcca tcggactctt
    15601 tacaatcagc caaatagagt atataatttc ttttggataa ggccagctta gctcagttgg
    15661 tagagcaacg cactcgtaac gcgtaggtcg taggttcgat ccctatagct ggcattaaaa
    15721 gagaagacag atatatcaag gatttttaat ccattgatac atctgtcttt ttgtttaaag
    15781 gaaataaagt atgctttctt agcaatagag catgtattat ttctataaaa atttaggaga
    15841 ataaaacgac tagcaatata gctgtgaaat caaatatcac atgaactgcc caacttgtaa
    15901 tgatcgagtt gcttttaatg gcagcttggt tgaataacaa tcttgccacc ccttgtatca
    15961 aaaggatgtg tgctacagtg tgtaaaatat ttccattatc ataagtactg taatggataa
    16021 atccaaagat gattgctgac aagaaactag cgacaggaat gctgaactta ctagaaaaaa
    16081 tagcgagaaa atacactgag aacaattctt ctccaagtat catgataggc aaaataataa
    16141 ataataacgg gctgaaagcc tcatttattg gattgcctgt taaaccccat ttcaaaattt
    16201 gttgcaaaaa taccgagact gcggcactga ttactacatt gataaaaaaa tatttggcta
    16261 tatttttgac aggagcgaca ggtttcgaga acattttttt cgtatctttt ttaccaaaaa
    16321 caagtgtaaa tgctataaat ccagtgatag ttaaagaaaa aatgctaata atggatggcg
    16381 caaatagcaa ccctaacaaa ccgagtacaa cgacaatagt gcccaatatc ccttttttaa
    16441 gttctatttt ttttcctaaa atgttattca tgataataac tcctactatt cagtttttga
    16501 agatagagtc agtatacatg aagagttaaa ataggcaatg tttttttatg gatatttgta
    16561 ttgctaaaaa tttatcttat atattcattt tgattatact acttttattt gtaaaaattt
    16621 tctagcaaaa ccaagtgctt gcaactgatt aagcgtacaa ttttttagat gttccgagcg
    16681 tacttcaatc atttcaaagg agttgctact taaatcgata ttttttaaat cagtatcaaa
    16741 aaagctagca ttttctaaat cattagtaga aaacattatt ttagtgaggg aacagtctac
    16801 aaaatctgcg cttgataaga cagagtgctc aaaggtactt tcttttatgt ttgaaccaga
    16861 taaatttaca tagtccattt tacaattctc gaataacgtg ttcccaatat aactttccat
    16921 caatttagta cctgttaatt tacaattgac aaatttcacg cgatgcaaca tgctttttgt
    16981 caatatacag cctgaaaaat cacagttttc gaatatacag tcggtaatct ccattctttg
    17041 aaaatcattg gaagcaaaaa atgcatactt gaaaatagat ttgtaaataa ttggatggca
    17101 gattatttgg ttttcgatga cctctttttg tgaaaggata ttatacagtt caaaatcttc
    17161 gttttcatag atatgaaaaa aggatccttt attcaagctt gcttcattaa ctttaggaaa
    17221 aatcatattt aattacctcc attttcataa agtcatatta acaaaagcta aaccaactta
    17281 cattagcaga aaatgagata ggttttcgcc tttttcgata acgatagtgt cgctatctct
    17341 tgaaacgttc ttagaattgc cctgagagac acaaattagg cgtaattcta ataaaaatct
    17401 tagaataaaa atttttactg atttaattta gaatgttttt aaaataaaaa tcgttgccat
    17461 aacagtgtat tgaaaggttt taacaatcca gtaatgattt aaaaaaatct agatgtagcg
    17521 tatactttgt ttatagaatg tagtgggaag aaatatattt ttgggaggaa atcgtgatgt
    17581 ctaaaagtga agaaatagaa aacatggtac taaaattata tgatctcgtt ttaaatccag
    17641 agatcaaaga aaaggaacgt atacttttga tagacgcaaa gacaggctta gaaaaaggtc
    17701 agtattatcc taaagtcata aataatttgg aacgtagttt acgtccgtta gcaatcaggg
    17761 gagaattgtc taaaccagta tcaccgtttt atatggagat atcaacaata ggaaaatttg
    17821 aaaaagaatt aggtcgagga atggcttcgg caccgattac ttttgggcat ttataaaaac
    17881 gagttattca tctcaatgaa ttaaaaagta tagtcaatct cataatgcag gctaggttca
    17941 tttatttgaa cagagtctgt atttttttat tctaaataaa gaaacagatg tttctttata
    18001 ttgtatttta tcctttaatt aacacaaaaa cagctagtat aaactaataa tgttaattaa
    18061 aagtgtattt tatgaaacta tcgttattta ttaatgttgc atttttgtaa gttaaaaatt
    18121 ggaaatatag attgaaaaaa tgaaagcaat aagtaaaata aaatgaatat atgcgaaaaa
    18181 ataatttaca ttaggaaaaa ccttgtaaaa acagtttttt ggcatattta ttttttataa
    18241 atatttgtaa aataactatc aattttttag ttaaaagatt ggaaatgagt gggggaggaa
    18301 ttgaagaaag gatttttgag agatgatata gtaggtttta tttttagtta aaatagggga
    18361 gatagaaaaa atgaaaaagt gtagaaatat tattttatca atgttattta ttattactaa
    18421 tataacatca ctgattcctg ttcatgtcta tgcggatgca ggcagagata tcagcagtaa
    18481 tgtcacttcg ttgaccgtgg acccaacgaa tattacagat ggaggaaaca taaaagtaaa
    18541 attctcgttt gacgaaaaaa aacaaaatat ccaaccaggt gattatcttt ggatcaattg
    18601 gccaagtgaa ggaaatattc gcggtgaagg attccaaaaa gaaatcccat taatgattga
    18661 aaataaaaat gttggaactt taacggtcag aaaagattct gcgcaggttg tgtttaatga
    18721 aaatattaaa aacctagact cagtagaagg ttgggggcaa tttgagatac aggccagaaa
    18781 cgtaaccgat accggtgaag aaaatacggg accattcacc gtgacgagcg gtgataaaac
    18841 agctactgta aatgtgacaa agccagcttc tggttcttct tctagcgttt tttattataa
    18901 aacaggagac atgctacctg aagatactaa gcacattcga tggtttttga atattaacaa
    18961 taacggcact tatgttgaac aaccagttaa aatcagtgat gaaatccaaa gtggacaaag
    19021 attagatcca agtacgtttg aaattaatca aatacactta ggtgaacaga aggtttatag
    19081 aggagaagag ggaatccaac aatttttaca agatttcccc agcgctacat ttaatttttc
    19141 agtaactgat aattacattg aaataactat accaaaaaac tttgtcaatc ttaggaaaat
    19201 aatggtgagt tataagacga tcatagaaaa cccagaacaa ataaattttg agaatcattc
    19261 ggaagcttgg tttaaagaat ttaataaacc tgctgttgat ggagaaagtt tcaatcatac
    19321 agttaaaaat atttcagctt ctggtggagt caacggtaca gttagaggcg aattgaagat
    19381 tttcaaatat atcaatgaca cagagattgg tatcccaaat gtgactttcg aattaagacg
    19441 agcagatgaa cagcctattc aaggacagtc tagtatcctg ttgacttcga atgaacaggg
    19501 agaagctagt atcaaaggcc tgcaagtagg agactatgtt gtaaaagaaa aagaagcacc
    19561 caattggatt gattttgatc cactaagttc aaatgaactc aaattctcca taaacgaaaa
    19621 tgatacagag ggagtcagtt tacctattta taacaagaaa aaggttacga acatcacagc
    19681 aactaaaatt tggaacggtg gaaccactcc aagaccgagt atttatttta aattattcag
    19741 agcaagtaca aacaattggg aaccagttcc tgatgcagaa acaaaacgat tagacaatgg
    19801 aataacttca gtgacttggg aagatatcca acagtatgat gatagtggaa acgaatatac
    19861 gtttaaagtg caagaagtag atcaaaacgg aaatgattat gtcccttcag gttatcaaaa
    19921 aattgaaaac gggctagtcg ttacaaatga gaataaagaa gtcatttcag tctcaggaca
    19981 aaaaacatgg gaagacaatg agaaccaaga cggcaaacga ccgacgacga tcacagtaaa
    20041 tctattagcc gacggtcaac cgatccaaca caaagaagta agtgaaaaag atgattggcg
    20101 ctatcgtttc acaaatctgc caaaatacag agacgggcaa gaaatcatct atactgtaac
    20161 ggaagacaac gtgcccgaat acagtacgac gattgacggg tataacatca aaaacagtta
    20221 tacaccggaa aaaacaaata tatctatacc aggtagccat ataacaccgt ggaaaaattt
    20281 tccagagaag acagagagag agaaaattag aaatctattc tctcaaaaat tgcaaatatt
    20341 tgctcataca ggagaatcca gcgaacaaag aagcaattat attagtaaga gagctgtacc
    20401 taaacagata acaaataaat caaaaagcat tcttcctaaa acaagtagta aaaaatctag
    20461 ttttgctgta atcattggtt tattgatagt aactatctgt gctgggatat tcttacaaaa
    20521 atataaaaaa gtttagttag aatataatat tttttgttaa atatgactga aatcaaaaga
    20581 ataaaattcc gatttataat cgaaaaaaga agcattttta tatatgcttc ttttttcgta
    20641 gaatcaataa atatggattt ggctaactat ggaagaatac tcgtattagt tttcagcgtt
    20701 catactagtt gttacattgt ttgattggcc aaaagaattt ctgatatatt ttgtgctaaa
    20761 taaagaaaaa gacgcttgaa ttgggaaata agaaaactac tctatcatta caaattttca
    20821 taaactggca gatgttctaa gtaaacaagt atcttttcaa agtcggaaaa atccataatc
    20881 aacgtagtgg tattgatatt tggatgaaag cctacggtat cttgacgatc aatagcagca
    20941 tcgatcacga cttggatttt tttctctttg tcgtgcatca atgctaatgg agtcactgta
    21001 cctgctggaa cgcctaggag gtcaggaagc tgttcttcag aaacaaaaga taagcgcttt
    21061 tcttttaatt gttcagctag ttgttttaaa tcggcgtgct tttcatcagg caagatgaca
    21121 agatagattt gttttccttt tcttgatttc aataatagat tttttacttg cggaccaggt
    21181 agggaaaaag ggacattttt gactgacgta atcgcaggat gatcgacttt ttgaaaagag
    21241 atacccagtt tttttagtag ttcataagct tcttgttcgg ttgcacgact catcgcgcat
    21301 caccctcctt tttttattag tgtatcataa aaaagagttg acaaatgaaa aataatcatg
    21361 taaattacac gtaaagttaa aacaaatgac atcgaaaaga agagtagccg ttaggtgttt
    21421 ttagagagtc tctggttggt ggaaagaggc agcagttaac cgtgaaacac atcttggagt
    21481 cgattttctg aagcgtatag taggaaaatc cggggagccc gttacagctg cggtcgttgc
    21541 tagatgacca gataaggctg gcttttccgt gaggagtcgg taaaaaaagg tggaaccacg
    21601 tgattaacgt cctttgatct tcggatcaaa ggactttttg ttttcatctg aacggcaacg
    21661 actgtgtgag gttttttctg caaggaaaaa ataaacagag gtggaaccac gtataatacg
    21721 tcctcttggc atttgccaag aggatttttt tattttaaag gaggaaaaga agatggagta
    21781 tttgattgaa gttatgccgc aattattagt aggagcactc acaacattga aattattttt
    21841 atttaccttg attggctcat taccattagg gattgtttta gcattaggat tgtctttgca
    21901 ttttaagccg ctacgctact tgcttcaaac atatgtatgg gttatgcggg gaacaccgct
    21961 gttgttgcaa ctgattttta ttttttatgg gttgccgacg attgggatcg tttttgatcg
    22021 tttcgaagca gcactcattg cctttatctt aaactatgca gcttattttg cagagatctt
    22081 tcgtggaggg atacaatcga ttcctcaagg tcaatatgaa gcagcgcaag ttttgcaatt
    22141 aagtcccttt caaacggtga cgaaaatcgt catcccacaa gtgacaaaga ttgttttacc
    22201 ttctgtaggg aatgaagtta tcaacttggt caaagattct tccttgatct atatattagg
    22261 tttaggtgac gtaatgcgtg ctgggaaaat cgcgatggaa cgcgacgcga ctttactgcc
    22321 tttgctaggc gtggcaatca tctatcttac attgactggt attctaacaa tcataatgaa
    22381 acaagttgaa ggaaaattaa attattaccg ctaactgata ggaggaagaa atatgattga
    22441 attgaagaaa gtgaacaaag catttggtga aaaaaaaata atcaaagatt tgaatctaat
    22501 cattccagat gggaaaacat tagctatcgt aggtccttcc ggtggcggta aaaccacgct
    22561 tttacgtatc ttggctggct tagaaagttc tgacagcgga gaattttatt tagacggtgt
    22621 accgttcaac ccattcgagc ttaaaatgaa agaacaagtt gtaggagtcg tattccaaga
    22681 cttccagcta tttccacatc tgaatatttt tgaaaacatt accttagcac caaaaatggt
    22741 attgaaacag acaaaagaag aatacaccaa aaaagcagaa gaattagcgg cttcattagg
    22801 gattagtgat ttattgaata tctatcctta tcagctttct ggcggacaaa aacagcgggt
    22861 agcgattgcc agagcattgg ctatgaatcc acgggtattg gcttatgatg aaccaacaag
    22921 tgctttagat cctgaattac gccagcaagt cgagcgtttg atcctatcat tgaaagaaga
    22981 tggggtaacc caaattattg tcacccatga tttagtattt gcagaaaatg tcggtgatca
    23041 attactaaaa gtttccccaa ttcattaaga aaggagaaga tagagatgaa aaaaaccagt
    23101 tttctattcg ctttgatcgc aggtcttctt ctttttgcag gctgttcgaa caaaaaaact
    23161 tcagcagata attgggcgac tatcaacgaa gagaaaaaaa tcgttatagg tttagacgat
    23221 acatttgttc ctatgggatt tagagataaa gacgggaagc tcacaggatt tgatattgat
    23281 ttagccaaag cagtctttga acaatatggg attacggtag actttcagcc cattgactgg
    23341 tcaatgaagg aatttgaact gaacaatgga acgatcgatt tgatatggaa cggctattcc
    23401 aaaacgccgg caagagaaaa gaaagtgcaa tttacaaaac cttatatgga aaacgatcaa
    23461 gtgctgatca cacctaaaga atcaggaatc acaaactttg gacaaatgaa taataagaga
    23521 ttaggtgcgc aaaatgggtc atctggttat gatgtattta cgaaacaacc agaagtatta
    23581 aaagagatag tcaaaaacca agatgctgtt ttgtatgata gttttaatga agcattgatc
    23641 gatctgaaaa gcagacgggt cgatggtctg ctgatggata aagtatacgc agactattat
    23701 ttgaaacaaa gaaacgaact agaagacttc aacataacaa aaggttctta tgagagtgag
    23761 gattttgcag ttggtgcacg caagtcagat agtacattag tgaaaaaaat caatgaagcc
    23821 ctagatcaac tagagaaaac aggtgaattc caaaaaatat ccgataaatg gtttggcgaa
    23881 gatgttacgc cgagaaatta acaaataggg gactgtgaca aaagacgtgt cacagtccct
    23941 ttttccgaat aaacagtgtt ctcctgccaa ctccttgtga ctcggagctg aatggcaggc
    24001 tcacaacctc ttggtaaacg gtgttcaaaa gccagttttt cggtattaag ccaaatttat
    24061 gcaaaaatgt agaaagccat tttcacaaaa tttttcttac tactcgaaac taagcgactt
    24121 tttcacaacc tcctttacat aattttattt tgttgtggaa ggggtttcgt gttattctaa
    24181 aagaggaacg attgaaggtt ataggaaagg aagagatgaa tggaacacaa agaacttacc
    24241 tcatttccaa aagattttct gtggggctct gcttctgcag cgtatcaagt agaaggagct
    24301 tggcaagaag atgggaaagg agaatcagtc tgggatcgat ttgtacggat acctggaaag
    24361 acatttaaag gaacgaacgg tgatttggca gtagaccact atcatcgtta taaagaagat
    24421 attgctttaa tgaaagaaca aggtctgaaa gcttaccgct tctctgtagc ttggacacgg
    24481 atttttccta atggacgagg agaagtcaat caagctgggc tcgcttttta tgagagattg
    24541 atcgacgaat tgattgaaaa cgatattgaa cctatgttga ctttatatca ttgggatctt
    24601 ccacaagcat tgcaagatga atataatggt tgggaatcac gtcagatcat tgaagatttc
    24661 actcattatg cagaaacatt atttgaggca ttccgcggga aagtccatta ctggattagt
    24721 ttgaatgaac aaaatatctt cacttcatta ggttatttgt tagcagcaca tccgccaggt
    24781 gtgacagacc cgaaacgaat gtatgaagtt aaccatattg ctaatttagc aaatgcatct
    24841 gtcatcaata aatttcacga gttagaaatg cctggaaaaa tcggaccaag ctttgcgtat
    24901 acgccaaatt atccaattga cagtaatcct gaaaatgttc tggctgctga aaatgcagaa
    24961 gacctgatgg ccaattattg gatggatgtc tatatgtggg gaaaatatcc gattgctgcc
    25021 atgaggttct tagaagaaaa aggatgggca ccaacgattg aagctggcga tgcagaattg
    25081 ctagaatctg ctaaaccaga ttttcttggg atcaattact atcaaacggc gacgaatgca
    25141 ttcaatccat taaacggagt tggtgctgga aaaatgaata cgacaggaaa aaaaggttca
    25201 tcagaagaaa ctggagttcc tggaatgtat aaaaaagttg agaatccatt tgtcgaacga
    25261 acaaattggg actgggagat tgacccagaa ggattaagga tcggactgcg tcgtatcaca
    25321 agccgttacc gcatgccggt actgattacg gaaaatggct taggagagta tgacaagttg
    25381 acagaagata aacaaatcca tgacgactat cgaatcaatt acttacaaag ccacgtcaaa
    25441 gccatcaaag aagcaatttc ggatggagca gaagtcctag gctattgcac ctggtcttat
    25501 acagatttgc ttagctggct gaacggttat caaaagcgat atggatttgt atatgttgat
    25561 caagacgaaa cacaagaagg atctttggaa cgatataaga aagacagtta ttactggtac
    25621 caaaaactga ttgaagaaaa tggagagaac ctttagttca catacttaaa acaagaaggt
    25681 acggctggat atggccgtgc cttttcttga taaaatcatt tagaaattaa gaaaaactgt
    25741 aaaataagct gaaaaatgaa agaaagcgtc agttctttca aacaaaactt tagttccctt
    25801 actttttttt gtataatgaa acttgatgaa atgagggata ataaatggca caaaagaaac
    25861 ggcctactaa aaaaaggaaa aagacgaaaa aaacgaaaaa gcaaaaacag cagcaggaac
    25921 aaatgctgac gattggtgtt gggtttgcct tgattttatt tgctgtcttc ggctttttaa
    25981 aattaggttt tttaggaata ttgattgcaa acggctttcg gatcattgca ggaaatactt
    26041 accaaatcct ctgtctttta ttagccgtat taggattttg gattgtcatt aagaatacag
    26101 agttttcaat tggtaaaaac cgacgctggt ttggcggcat actcttttat ttcggtatct
    26161 tattattgtt acatgcccat ttatttggca aactccatac tggggaacca aatatcatgg
    26221 ggacgacatg ggatttgtta gccagtgata taaaacaaag tcaagtagac aataacgttg
    26281 gtggtgggat gattggagca atcctttatc attttactta cttcttgatt gcacagcctg
    26341 gaagttattt agcagcagtg ctattactgg caggaggagc attcctgttc agtaatctgg
    26401 aaggctatca gctgttaaat ggtatccaat caattggaga acgagtacag gaattattgg
    26461 aaggtgatcc tgccaagcaa gctcgaaagc aagcggcaaa ggaagagaga atgaaacagc
    26521 gcgcagaagc gaaagaagca aggcgcttag ctgcaaaaga agctgcagaa aaagaagctg
    26581 cagaatatga gaagaaaaaa gcggtgagcc agcaaaggga aaatactgct gatgaatggc
    26641 aggaaccaga aaatacagag ccggagcagc taagttttgt tccaatcgac agttttcaag
    26701 aaaatatcca tcctgcgaat ctagagaaac cagtaccaga tacaccaaaa cagaccaata
    26761 cagcagaagg tttttcagat gagttgccag aggatgacgg tacctcatta gaatttgaga
    26821 ttgaagcaga acaggaaaat caagactatg aattaccgac agttgatttg cttgattcta
    26881 taccaactgt ggatcaaagt gatgagtata aaaaaattga aaaaaatatc ggcgtattag
    26941 aacaaacttt ccaaagtttc ggtgtcgatg ccaaggtcgt caaagccagc ttaggaccat
    27001 ccgtcacaaa attcgaagtc cagccggctg taggggtaaa agtaagtaaa attgtgaact
    27061 taacagatga tatcgcgctt gctttagcgg cgaaagatgt ccggatggaa gcaccgattc
    27121 caggtaaatc actgattggt attgaagtac caaatggaaa gatcagtatg gtttccttta
    27181 gagaaatcat cgaagcacaa ccaaaccacc cagataaatt actagaagta cctttaggac
    27241 gtgatgtttc tggacgggta caaacggctg atctttcgaa gatgcctcac ttactcgtgg
    27301 ctggttcgac tggtagtggg aagtcagtag caattaatgg gattatcaca agtatattaa
    27361 tgcgtgctaa gccccatgaa gtaaaactga tgatgatcga tccgaaaatg gttgaattga
    27421 atatgtacaa cggcatacct catctgttga cgccggtcgt gacgaaccct agaaaagcag
    27481 cgcaagcctt acaaaaagta gtacaagaaa tggaagaacg atatgaaaaa ttcgcggcaa
    27541 ccggagtaag aaatatttct ggttacaatg aatttgttca acagaaaaac ttggaaaacg
    27601 gaacgaaaca tccaacctta ccattcatcg tagtgatcgt agatgaatta gctgatttga
    27661 tgatggtagc cagcaatgaa gttgaagatg cgattattcg tttagcgcaa atggctcggg
    27721 cagcggggat tcatatgatc ctagctactc aacgtccaag tgtggatgtt atcacaggaa
    27781 tcatcaaagc aaatgtacct tccagaatgg catttgcggt atcaagcggt acagattctc
    27841 ggacgatcat tgattctaat ggggcagaaa agctcttagg gcgaggagat atgctattct
    27901 tgccaatggg tgagaataaa ccgatccgtg tgcaaggagc attcatttct gaccacgaag
    27961 tagaacgggt cgttcaattt gttacagatc agcaagaagc tcattatgaa gagaaaatga
    28021 tgccgacaga tgaagttgaa acgacaggtg ctccagaaca gccacaagat gagctgtttg
    28081 aagaagcaaa agcacttgtc gttgaaatgc aaacggcaag tatttccctt ctccaaagaa
    28141 gatttcggat cggttacaac cgagcagcac gtttagtaga tgaactggaa gctcatggag
    28201 ttgttggccc gtcagaagga agcaagcctc ggaaagtatt cattgagcag gaagaaacat
    28261 cagaaacgtt gccggacgat aatgacatgt aaaacttgtg tgatgaaggg ttgaaaaacg
    28321 aataaccaat aaaaagacaa ggcatgatga taccaaaaga aaaaatggtt tttttccatc
    28381 ttttctaata cggtatgatg tcttgtcttt ttagtttttg tgagattaaa gttctattcg
    28441 atttatttgt gaagtattgc attaaggaaa tgaatcatgt atagtatgta gcgaaacttt
    28501 gagaaaaaga gggaaaatac tttggaaaaa cagtccattt atggcttgac gaatgaagaa
    28561 ttaatcaatt ggtttataga aaacggcgag aaaaaattcc gagctgccca agtttgggaa
    28621 tggttgtatc aaaaacgtgt aagtaatttc acagaaatga cgaatctatc gaaacaattg
    28681 atcgaaaaat tatcggagca ttttatcatc aatcctctaa aacagatggt cgtccaagaa
    28741 gcttcggatg gtacagtaaa atatttgttt gaactccctg ataaaaacat gattgagact
    28801 gtactgatga gacaagaata tggcttgtca gtttgtgtga cgacacaagt aggatgtaat
    28861 atcggctgta cgttttgtgc aagcgggctg ctcaaaaaga accgtgatct gactgctgga
    28921 gaaattgttg cacagatcat gatggtccaa cattattttg atgagcgcaa tcttggcgaa
    28981 cgcgtttcac atgtcgttgt aatggggatc ggtgagccat ttgataatta cgacaatgta
    29041 atggactttt tgcatatcat caatgatgcc aaaggattgg caattggtgc tcggcacatt
    29101 acagtttcca ctagtggatt agcacacaaa atcaaggaat tcgctaataa cggcttgcaa
    29161 gtcaatctgg ctatttcctt gcacgcgccg aataatgagg tgcgaacatc gatcatgcgg
    29221 atcaaccgaa gtttcccaat tgagaaattg atggaagctg tggatgagta tttagagaaa
    29281 acaaaccgtc gaatcacgtt tgaatatatc atgttgaatc aagtaaatga tagaccagag
    29341 catgcgcaac aattagcaga tctattaaaa gataagaaaa aattagcata tgtcaacttg
    29401 attccatata atccagtcag tgaacatgat caatattctc gcagtccaaa agctgatgta
    29461 ttgagatttt atgatgtatt gaagaaaaac ggcgtaaact gtgtgatacg taaagaacat
    29521 ggtacagata ttgatgcagc ttgcggacaa ttgcgaagca agcaaatgaa aaaaacagtt
    29581 gccaaataat cgtatcctac tcgttttttc aattaccata aaaggagcag ttttcttaat
    29641 taaggaactg ttcaacttaa ataagagaaa agattctata gcgaaagcta taaagctttt
    29701 tttgacaaga aaaaccctca tcaagcaaag aaatgtcctc aatttgatga cagcctgctt
    29761 gatgggggtt ttagcaatta tttaactgat tttcttatat ccttgctggc tttcttgtgt
    29821 agcatgataa gtttctacgt caagaatggc ctgtttaaat ttttctcggg tgatttcata
    29881 aggcacatgt ttaatatcat ttgttgccat ggctttatct aagattgctt ctaaatcggt
    29941 cgtgacattg agattcatgt cggttaacga tactggaagt tggttctttt tcataaacac
    30001 atagatttta tcaaacaaat cgaactgctg atccatcatc aataaggtca gtacaccata
    30061 actgacagat gctccgtgaa ggtatccctc cattttttct agaacagtcg taccgtaata
    30121 gaatgagtgt gccatagcag aattatagtt attgttaact aaaacagaaa ccaatccggt
    30181 agtaacaatg atatccgaaa cgacttgttc aattgcatat gagggacgat cgtcggcact
    30241 atctttcaat gcttgcgtac cataagtcaa gagacgatca atgcacattt ttccgatttg
    30301 gattcctaat ctatccgtgt agcctagatc atcgccacga gcagaaaaag tagattcgac
    30361 ttctttggat aaagcatcgc caatacctgc ccataagtat ttatcaggtg cttcggcaat
    30421 aattgctgta tcaatgaagg tgtgtacagg tggttttgaa ggaaagaaga gtccgtccat
    30481 tacgccttct tcgttataga tgacacatac cgcagtgacg ggcgaacagt tcgaaccaat
    30541 agtgggaaag gtgaagactg gtttagctag tttttcacca atgactttta cagtatcgca
    30601 agcacggcca ccaccgactg caaacaggac gtctgctttt tggacacttt catgctggat
    30661 caactgttca atatttccat aagttgaatt acccccgtac cagagactgg cgacaacctc
    30721 tatttcctgt gtcaaagcta cttttatttt gttttctgcc tttgaaagtg cagtcttccc
    30781 tccaatcagc actacttttg tcccatattc tttgacgatt ccatttgctt tttcatacgc
    30841 atctgttcca atggtataat ttggtaagaa aacactttga ctcatattca tttccttctt
    30901 tcttcgttga aacgggttaa aattttaaag agtgatcgat ctgactgcgg ctgtagatgg
    30961 agtagaggtg aacctaagac aggataagtg atgaataagg tggcatgaac accttgaaat
    31021 catcaataag tatcctaaaa acgaacaagt acaaaaacat tgaaaacgac aataatgaat
    31081 ttttgttcct cttagtattt ctaccgattc cctttgcttt tttgtaatta tctaaaaatt
    31141 ctaaaaatta agattattat atgaaaacag gttttatttg tcaattcata attggttttt
    31201 tttaaagcaa aagataatct atatcatgat gaacaaacag agttttttcc tccaattgat
    31261 ggctttcctg atctttccta ttttgaataa agtgtttctg tataattttt ttattttata
    31321 agtaagataa ataatgaaag aatagagata ctgattggta gctaaagatt tttgagcgag
    31381 aacatttcgt tttttcaaaa ggactgttag aataagcaag aacaaggggg aagacgtatg
    31441 ataatcagtg aatttgaccg taataatcca gtattgaaag atcagctttc tgatttactg
    31501 agactgactt ggccggaaga atatggagac agctcggcag aagaagtaga agaaatgatg
    31561 aatccagaac gaatcgcggt agcagcggta gaccaagatg agttagtagg atttattggt
    31621 gcaatccctc aatacggtat cacaggttgg gaattgcatc cattagttgt agaaagctcc
    31681 cgacgaaaga accaaatagg tactcgatta gtcaattact tagaaaaaga agtagcttcc
    31741 agaggaggaa tcacgattta tttaggtacg gatgatttag accatggaac aacgttaagt
    31801 caaacggacc tgtatgagca tacatttgat aaagtggctt ccatccagaa ccttcgtgaa
    31861 catccgtatg aattctatga aaaattaggt tataaaatcg taggtgtctt accaaatgca
    31921 aatggctggg acaaaccgga tatttggatg gcaaaaacga ttattcctcg accaaattct
    31981 caataataaa aagaggttgt gacagaagta atcagcttca agaaataaga aggaatttac
    32041 gaaaattact tcttgaattt ttgtgaaatt ccaacttatt tccgaagaag ctacttttgg
    32101 aacaccgtgt accagaggtt gtgaaaaagt cgcttagttt cgagtagtaa gaaaaatttt
    32161 gtgaaaatgg ctttctacat ttttgcataa atttggctta ataccgagaa actggctttt
    32221 gaacaccgtt tattcagata agggactgtg acaagacttt tgtcacagtt tctttttgtt
    32281 tattcttttt tatctttgta tggcaataat agacaatata acgaaaatta tttaatggct
    32341 tttggaagac catggaaaac cttgtacaaa gctatttttt ctgaaaaatt ccttgaaacc
    32401 tcacgaaaaa atcattattt tatgaaaaag acaaaaaaaa gtgttgattt tttaataatt
    32461 attcattaaa ctcttaaaca acttcagaaa atattaatta ttctgaaaat tccaataaag
    32521 gggtacgtaa aatgaaaaag aaatttacat ttggtttggt tgcggtatgc ggccttgtac
    32581 ttgctggatg ttatggcggc agttcagcca caagcagtag ttcagcaaaa agcggttcag
    32641 cagatggagg aggcgtattt aacttagtcg tgcctcaaga aatgcctaca gctgacttat
    32701 cagttgcaac agatacaatc agttttacag cattgaataa cgtttatgaa ggaatttacc
    32761 gtcttgatga agacagcaaa ccacagccgg caggagctag cgagttggca gaagtcagtg
    32821 aagacggatt aacttacaaa atcaaattac gagaagacgc aaaatggtca aatggtgatc
    32881 ctgttacagc agcggattac gtttatggct ggcaacgaac agtagaccca gctacagctt
    32941 ctgaatatgc ttacctgtat gcgccagttg aaaatgcaga agacattaca gctggaaaga
    33001 aagataaatc agaactaggg atcaaagcag ttggtgacta tgaattagaa atcaaattga
    33061 cgaaacaaac accatatttc caatatctgc ttgctttccc atcatttttc ccacaaaaac
    33121 aatccgtagt ggaagaaaat ggggatgcct atgcatctgc aagtgataaa gctgtttata
    33181 atggaccatt cacattagaa gattttgatg gaccaggaac agatacagaa tggacttata
    33241 agaaaaatga tcattactgg gacaaagata cagtaaaact ttctgaaatc aaagtcagtg
    33301 tagtaaaaga atcttctact gcattgaact tattcaaaga tggccaagca gatgacgtga
    33361 tcttgtctgg tgagttagca cagcaaaacg caaacgatcc agcttatact tctgttaaag
    33421 aagcgcggac aagctatatc gaattcaatc aacgtgaaaa gaattcacca ttcaacaatg
    33481 tgaacctaag aaaagctatt tcttattcta tcgatcgtga agctttagta aaacaagtac
    33541 taggtgacgg atcagttgtc tctacaggat tgatcccatc agatatggta aaaagtccaa
    33601 caacgaacga agactttgca aaagaagctg gaaaattagt ttcttatgac aaagataaag
    33661 caaaagaata ttgggaaaaa gcgaaaaaag aattgggcgt tgattcttta gaatttgatt
    33721 tgatggcttc tgatgatgat tcatcgaaaa aagtaatcga atatgttcaa aactcaatcc
    33781 aagaaaactt ggatggcgta acagtcaaac caacacctgt tccattctct gtacgtcttg
    33841 accgctcaac ttcgggtgat tttgacgcag tactaggcgg atgggctgct gactatgcag
    33901 acccaagcag ctttactgat ttgtttgtca caggtaattc atacaaccgt ggtcgctgga
    33961 gcaatgcaga atatgacgaa gcagttaaag cagcttcatc aacagacgct ggcgatgaac
    34021 aagcccgttg ggatgatttc caaaaagcaa tcaagatcat ctctgatgat atgggtgtcg
    34081 ttccggtgta ccaaaaagca gaaggtcacc tagtgaatga aaaaatcaaa ggtatcgttc
    34141 accatgcggc aggcgcttca tgggattaca aatggacata cgttgaagaa taatcgttaa
    34201 taccgtgagc atgagaaaaa acgaggctgc ggcaaatgtc gcaacctcgt tctcatattc
    34261 acttatccta acaaagaaaa aagcatgaaa atagcagaaa gagcaattag tattccggca
    34321 atgatcagcc aaaagctgta cataccgtag ctggcagacg agagcgagga aaattctggt
    34381 tttttctttc ggttccttgt tcgtgcaaga tggaccgatc gctgaaaatg atcgaagaaa
    34441 cccgaagaaa agacccataa aaaaccgccg ataatcagaa acggcaatga ccataagaat
    34501 agatcattag ataattgaat gagtgtaaag gaatggttga tgagattttt tattaaaata
    34561 accagaatca gtagaaaagc tactgcgtag gggatagatt tttttttcat ttgattgctc
    34621 ctttattttt ggttcattat ctaataatgt agcgaaacat ctgtcagaag tcaaaagcta
    34681 gggggaaaca ttagtgaata gttatatcaa atatgtatta aaacgtgtct ttttcatgat
    34741 catcacgctt tggttaattg caacaatcac ctttttcttg atgcaattgc tgccgggcac
    34801 gccatatacg aatcaggaac gtttgagtcc tgaaacaatc gagatgctaa ataaacaagt
    34861 cggtttggat aaaccagtta tcgtacaata tgggatttat ctttctaatt tgcttcaagg
    34921 agattttgga atttccttcc aatttaaaaa ccagccagtc gcacatttgt tagctggaag
    34981 aatcggacca tccttgcagt tagggttaca ggcaattatc tttggaacag tcctagggac
    35041 gattttagga acgatctctg ccatgaagca aaatacatgg gcagatacat cttctacact
    35101 cgtagcgata ttaggtcgtt ccattccaaa ctttgtattt gctgttttat tacaatatat
    35161 ctttgcaatc aaattacaag ttttgccaat cgcaaaatgg gatggctttg tgtacacaat
    35221 cttaccaaca attgcgttgg ccatgtcgcc gcttgctgac tctgctcggt ttatccgtac
    35281 ggaaatggtg gaagtactgc atagtgatta tgtggaatta gcaaaagcaa aaggattgag
    35341 ccgttgggaa atcgccttta aacatggtct tcgaaatagt ttgattccat tgatgacttt
    35401 attaggaccg ttagctgtag cattgatgac cggatcactg gtggtagaaa atatctttgc
    35461 tattcctggt atcggggaac aattcgttaa gtcaatcaca acaaatgatt atcctacgat
    35521 catggctgta acgatccttt actcatttat gctgattttt gttattttga tcgtggatct
    35581 attgtacggt ctagttgatc caagaattcg tgtttcagaa gggagccgag gataaatgga
    35641 aatgatacca aagcgttatg aaacagttgc agatatccct gcggatgaat ttcttccatt
    35701 acaaaaaaat accgaagaag aacgtgaaca gattactgca ccttctttga attttatcca
    35761 agattcatgg cgccgtttaa agaaaaacaa agctgccgtt atttcaatgg ttttactatt
    35821 ggtcatcatt ttgatctctg tgatcacaat ctttgtttct cctcatgatc caactgccca
    35881 aaacgtggct tatatcaatt tgcctcctcg tattccggga atcaatatcg atggattgaa
    35941 tggaaaagca atggttggtg gtgaacttgt tgataaatat gctcaagcaa acgtcccttc
    36001 aaacgtaaat ttctttttag gaacagacgg tttgggacgt gatgtattaa gccgcttatt
    36061 tatgggaatg agaatctcgt tgctgatcgc atttattgct gcattactag atgtaacgat
    36121 tggtgtagct tacgggttgg tttctggttt gttaggcgga cgtgtcgata acgtgatgca
    36181 acgttttttg gaaatcttat caggaattcc aaacctcgtt gtcatgattt tgatgttggt
    36241 cgtttttgaa ccaggaattt tttcaatcgt ggctgctatg gccatcacaa actggatacc
    36301 aatggcacgt atcgttcgtg cacaaacaat gaaattaaaa gatcaagaat atgttttagc
    36361 tggattgaca ttaggtgaat caagaatgaa aattgcattc aaacatattt tgccgaatat
    36421 ctctagtgtc attattattc aaatgatgtt tagtattcca tctgctattt tcttcgaagc
    36481 ctttttaagc tttatcggtt taggtcttac gcctccgtca gcttcattag gaacgatgtt
    36541 gagcgaaggg tacaagacat tcctgtatct gccttatcta ttatggattc cggcagtaac
    36601 tttatcggtt atcatgattg gctttaactt acttgctgat ggattgcgtg atgcctttga
    36661 tcctaaaatg aaagagtgaa gacgatgacg aaaattttag aagtgaaaga cttagaaatc
    36721 tcttttgata cgtatgctgg aaaggtacga gcgattcgcg gtgtcaattt tcatttgaat
    36781 aaaggagaaa cattggcgat cgttggggaa tctggaagtg gaaaatcagt gacgaccaga
    36841 agcatcatgc gcttgctgtc aagcaacgcc aatatagatg ctggtcaaat cctctttaaa
    36901 ggtaacgata tcgttggaaa atcagaaaga gagatgcaaa aaatccgtgg taaagaaata
    36961 gcgatgattt tccaagatcc aatgacctct ttagatccga cgatgcccat tgggaagcaa
    37021 gtcgctgagt cccttagaaa gcataataaa gtttcaaaaa aagagggaca aaaagctgca
    37081 ttagaattgc ttaaattagt tggaataccc gaagctgaga aacgtatcaa cagttatccg
    37141 catcagttct caggaggtca gcgtcaacgg atcgtgatcg cgattgcact ggtatgttat
    37201 ccggaaatcc tgattgctga tgaacctaca acagcgcttg atgtgactat tcaagcacag
    37261 attttggagc tgctgaaaga aattcagaca aaaatcgata catcaattat ctttatcact
    37321 catgaccttg gtgtagtagc gaatgtcgct gatcgtgtcg ctgtcatgta tggaggaaga
    37381 atcgttgaag ttggaacatc ggaagaaatt ttctacaacc cgcaacatcc ctatacttgg
    37441 ggactgcttg gttcaatgcc gacattagat agtgcgaacg atcgattgta tgctattcct
    37501 ggttctccac cggatttatt gaacccgcca aaaggagacg cattctatcc aagaaatgaa
    37561 ttcgcgatga aaatcgatgc agaacaagaa ccaccatttt ttgaactatc aaaaacacac
    37621 aaggcagcaa cttggctact tgctccgcag gcacccaaag tgacaccgcc agaagaaatc
    37681 caacgtcgct gggctatctt taaagagaaa caaaaacata cttacggtca aggaggaatt
    37741 gctgatgcca aataaactac ttgaagttaa aggattgaaa cagtatttca atgtaggaaa
    37801 aaagaatgaa gtacatgctg taaatgacat cagctttcac atttatgaag gagaaacatt
    37861 cggtttagtt ggagaatctg gaagcggaaa atccactact ggccgtacga tcattcgctt
    37921 gaatgaacct actgatggtg agatattatt cgacggtcaa gatataacga agatcaaaga
    37981 taaaaaaggt ttgacgaaat tccggcatga tgttcagatg atctttcaag atccatacgc
    38041 ttcgttgaat cctcgtatga aagtcagaga tatcattgcc gaaggaattg atgttaatgg
    38101 actagctaaa tcatctgaag agcgtgcaaa aaaagtcgat gatctattga gaactgttgg
    38161 attgaatcca agccacggta ctcgttatcc tcatgaattt tcaggtgggc aacgccagcg
    38221 tattggtatt gcacgagcat tggcagtaaa accgcgtttt atcatttgtg atgaaccaat
    38281 ttctgcacta gatgtgtcga tccaagccca agtggtcaat ttgttgcaag atctccaaaa
    38341 agaacatcaa ttgacctatc tatttattgc acatgatttg tcgatggtta aacatattag
    38401 tgaccgaatc ggtgtaatgc ataacggctt gttattagag atgggaacaa gtgatgaaat
    38461 ctataatcac ggtgttcatc cttatacaga aagtttgtta tctgctattc ctctaccaga
    38521 tccagaccat gagagaaaac gcagaagaat caaatatcaa cctgaaccag atgacggaca
    38581 agtacgtcaa cttcgtgaaa tcgcaccaga acattttgtc tatgcaactg agcaggaagt
    38641 cccatattac gcaaaaaaac taaaacgaca aaaggaatct cttctggttg ctaactagga
    38701 gggacataga tgctaaaagc ttttaaattc cgtatgtatc cgacagaaga acaaaaacag
    38761 caattgattc gtacttttgg atgtgctcga tttacctata accatttgct gaaaaagcgg
    38821 cagaaaagtt ggcaacaaac aggagtagcc aatttttcgc tcacacccgc tacattaaaa
    38881 aaagaatacc cattcttaaa agaagtagac agtcttgctt tagcaaatgc acagcttaat
    38941 ttggatcggg cttttcgcaa ttatttcaag ggacgtgcca gcttcccaaa gcttaaaacg
    39001 aaaaaaagta tgtggcaatc ttatacgacc aacaaccaaa cccgtacgat ctatctggaa
    39061 aatggctact taaagttacc aaaacaaaaa gaactaatca agataaatca gcatcggcca
    39121 gttgaaggat cgattcgctc cgctacgatt tctgctcgat ataatgaaga attttatgtc
    39181 gcactacttt gtgatgtttc gccagtaaaa aaagaatctt tagctaaatg gatcgggatc
    39241 gcctatcatc cgaagacatt gatccaaaca tctcgacctc tagaagtaac tttaccaaaa
    39301 tttcaccaga cagaagaaaa gctgcaacat gcacagcgga aattgaatgt gaaagtccgc
    39361 tccgctcacc atagaaagat caggttagat caggcaagca attatcagaa acaaaagaga
    39421 aaagtaatgg atctttatct gaaacaaaag aaccagcgag aagattatct tgaacaatta
    39481 tctgggaaat tggtcaaaca atatgactac ttatttgtag aatcttttcc aaaagaagag
    39541 gcacatgctg atttttctat tcacgactgg cataaattaa taacaaaatt gcgttataag
    39601 tcccaatggt ataataaaaa atttcttttg atcaataccg acggagcaga agaaagcaat
    39661 tccgtaagaa agagccaagt agtagaaaaa atgggcagac attcggttat caagggataa
    39721 aaaatgaatg aaactgatag gagcgttagg gttagccttg ttaataaaaa gtcttaatga
    39781 cttttgtttc taggaatttt tcttttgaag aaaagctcac taattatgac aaaccaataa
    39841 aacaatagca gaaaaagttc gtacgagctt tttctgctat tgttaatttt ttattcagaa
    39901 agtttacgaa tacatcaaaa ttctgaaaca aaaaacgtaa ctcacaaaga gttgtttttg
    39961 cgttttttct tgaatgatta ggtctgaatc ttttgctcac aaccttattc atggtgcccc
    40021 ggcttgagct gatagatttt tgaaggacgg ccgattccta caggacgttc accgatctca
    40081 tcgaaatatt ggagcatagc tttcttaaaa ttggaatgat cgatcgtttt ataatcgatc
    40141 cctaagaatt tagcaaatac ttttcgagct tccgtaatcg tgaaatcttt acctaaaact
    40201 tgtagaactt gcggctcgtg ttccatttta ttgactacac ggttgaatgc tttcaagatg
    40261 atttgactat ggtcaaaagc caaagtatct ttgccagaag actctccagt gactaaatca
    40321 agcgagatag ccacttctcc gctagataaa tggatcttgt tactatgacg ttctagtgtg
    40381 aaccagcgta cttccttggc atcatctccg gcgattagcg gttcttctcc aataaaggct
    40441 aagtagctga ctgtgacgac ccagcctcgc ggatctcgat taggcgtact gaatgtatgc
    40501 agttgctcaa tattttcttt tgaaataacc acaccagttt cttcctttgt ttctcttaag
    40561 acgctttctc cagttgactc atccttttgg acaaagccac caggcaatgc ccatgaattt
    40621 cgataaggat gcccttttct ttggatcaac aaaactttca gctgatcttc ttctttgtta
    40681 tagcacatca gtacgatatc gacagtcaaa gagggcttgt catattctgg acgttcctgt
    40741 ttttgatacc agttaagaaa ttcttcttca cttgctttat gttcataata taatttttct
    40801 tcttctttag aagcaaaacg gttcatctga ccacctccat tgacagtaaa agtacttttt
    40861 accttattgt agcagactct gaaaaaaaac caaggattta cttgaaaaat ctaggttatc
    40921 atttaaatat gaaaaataaa tggaagtatg agattgaata aaaagaaaag cagataaaac
    40981 ggcaatactt tataccgctc ttcacgaatg gcaaagaagc cacaaataac gatatatacg
    41041 tcaatgataa aacgcaaaat ccaagctgct gtcataaaac tgttcaaatg cccatggagg
    41101 ttaaaataac catacatacg aatataaaaa tagctgaata ttaaatgtgc taatgaaaga
    41161 aaagcaatac taagtgtaaa aaaaagatgt ttcttctgca tgattgttcc agtcccttac
    41221 taagatagat agtctttatt ataccacgtg tgaggggaga aataaaaagc cgttttttag
    41281 tagatatgaa acaaaacaaa aacccgcatt tattcaacct attcatcctt ttaaaggata
    41341 gattgaacgt agatagaagt cgtttatcca gtctttttca ttttgaaaaa aagctaacag
    41401 catgcttttt ttatggtata ctagcaagga aacgaattcg catcatgcga taaaggagga
    41461 agagccccgt ggcagaaaag gaaacttttt atatcactac gccaatctat tatccaagcg
    41521 gcaaacttca tatcggcaac tcgtatacta cgattgcatg tgacgcaatt gctcgttata
    41581 aacggttgat gggctttgat gtgttttatc tcactggagt ggatgaacat ggtcaaaaaa
    41641 tcgaaacaaa agcagaagaa ctaggtgtaa aaccgcaaga atatgtagat aaaatggcgg
    41701 ctgatgtcaa gaaattatgg aaaacgcttg atatcagtta tgataaattc attcgcacga
    41761 cagatgatta ccataaagca gctgttcaaa aaatatttga tcgtttatta gaacagggag
    41821 atatttactt aggtgaatat gaaggctggt actctgtttc tgacgaagaa ttctttacag
    41881 aaacacaact tgcagaagtg tacaaagatg acgaaggtaa cgtgatcggt ggtaaagcgc
    41941 caagtggaca cgaagtagaa ttggtaaaag aagaatcata cttcttccgc atgagcaaat
    42001 acgcagaccg tctattggaa tactatgaag aacatcccga attcatccag ccagaatctc
    42061 gtaaaaacga aatgatcaac aactttatca aaccaggatt agaggatctt gcagtttcac
    42121 gaacaacttt tacttgggga gtaccagtca agagtgatcc gaaacatgtg gtgtatgtat
    42181 ggatcgatgc attatccaat tatattactg cactaggata tggctccgaa gatgaaagtc
    42241 tattcgaaaa atactggcct gcagatgttc agatggtcgg taaagaaatc gttcgctttc
    42301 atacgatcta ttggccaatc atgctgatgg cccttgattt gcctctacct aaaaaagtat
    42361 ttgggcatgg ctggctattg atgaaagacg gaaaaatgtc taaatcaaaa ggaaatgtcg
    42421 tttatcctga aatgcttgtg gaacgttatg gtttagatgc actccgttat tatttgcttc
    42481 gtgctgttcc gtttgggtca gatggtgtct ttacgccaga agattttgtt tcccgtgtca
    42541 attatgatct ggcaaatgat ctagggaact tattgaatcg aacgattgct atgatcaaca
    42601 aatattgtga tggactcgtt cctgactatg cctcacttgt cactccattt gatagtgaac
    42661 tgtctacgac ggctgctaac gttgtcggac gttaccatga tgcaatggaa aaaatggaat
    42721 tcaatacagc attggctgaa atctgggtgc tgatttctcg tgcaaacaaa tacattgatg
    42781 aaacagaacc atgggtatta gcaaaagacg aagaaaagaa agctgaattg aatagtgtca
    42841 tgatccattt agctgaatct ttgcgtatcg cagcgatatt acttcagcca atcatgacag
    42901 aaacgccaga gaagatcttc aatcaactag gattggactc tgaaacaatg aatcttgaag
    42961 gattacactt tggcgaattt ccttcaggaa caaaagtagt tgcaaaaggt acaccaatct
    43021 tcccacgttt agatatggaa gaagaagttg cttttattca agaaaaaatg tctgaaggta
    43081 ctcaaacaaa cgaagataca gtcaaatggg atccagaaga aacagaactt gtttcaacga
    43141 aagaaaaaca aatcaaattt gatgtatttg aaaaagtaga actaaaagta gcagaagtca
    43201 tcaactgtca aaaagtagaa ggggcagata agttgctgca attccgacta gatgctggag
    43261 acagccaaga ccgtcaaatc ttgtcaggaa tcgctgaatt ttatcctgat ccaagcgaat
    43321 tgatcgggaa aaaagtcgtc attgtagcaa atctgaaacc acgaaagatg cgtggacaaa
    43381 tcagtcaagg aatgatcctt tctgcagaag caccagatgg ctctttacaa gtaatcgaag
    43441 caccaaaatc catgccaaat ggctcagaaa tcgcatagaa attcaaaggg ggtatgacac
    43501 tagttgtgtc ataccccctt tttccgaaat ttgagaagca attttcgtaa attccttctt
    43561 attacttgaa gccaatcata taatacagaa acagagaact atccaaaata aatcctagaa
    43621 aaagaagtac gagcttcgct gatttttgtt aatttagaat aatactaata ggaatcgtaa
    43681 aaacagaaaa aaagcataat gataaagggt cgggcagatt ttaattgatt catctggtac
    43741 tcttttttat tgtccttaca ttcataaagt ttgaatgcaa tgactttatt acatctatat
    43801 ttatatctaa cagtagcgtt gatgtgttaa ttataagttc tatcacttta tgttcaatta
    43861 gtttgtgctc ttatatgtgt gattgaaaat atagataaaa aaacaatcat cggctttgac
    43921 ttcgatgatt gttttcttta ttttgtaaaa atcctatcac ttgattttat ggtaaccttt
    43981 tatttttgtc ttcaaacggc ttggtaagag agcagtaagc agtgcaaatg ggatcgaaaa
    44041 gacataccag aaaatcgtac gtccgatacc ataatgttga tagagctttg tcaacatcac
    44101 gtgtaacaag atcaacccta aaagcaagga gccagctata aaccaatgat tatcccaatg
    44161 catgacttca ctaagtgcca tcactccaaa aggatagaaa taaaaataga tcccgactaa
    44221 ggtcatccgc cagttctttg taaatgttcc gatattcaat aaaaagaaaa tcgctgaaag
    44281 caaaataccg ataggcggaa aaagcccaac caaaaaggaa tacaacatcc cccacaagat
    44341 catcacagga cctttgatca atgcaacgat tgcgatgaac aaagtcagca atattagttt
    44401 ttgtgataac gttgcaacag tcattaatcc aaataaaatt aatgtgaacc aatgccaatg
    44461 ggactgctgt tgttctttac gggaaaaatc gacccggttg gataaataat ctgctaattt
    44521 cggataagaa cgcttaaaat ccataaactg ttcctccttc gtggaaaagg taggtttagt
    44581 atacgaaaaa taaaaaagaa atacatccgt cttaagaggg agtttttcac tgaaagtgga
    44641 gaaaaaagaa tggtaaatta aaatattctc agttatactg aaaattatac caaatttcaa
    44701 agaagaaaga ggatgggaat gaaaggcaaa ctaaaacgag aaatcaatct gtttggcgca
    44761 ttagctaccg ttatgggaac cgtgatcggt gcaggcgtct tcttcaaaac tgctgctgtt
    44821 actgctagta ctcagtctac aagtttgaca ttgctagctt ggcttttggg tggtttctta
    44881 acgatctgtg ctggattgac agtggctgaa ttagctacag caatcccgga aactggtgga
    44941 gctgtaaaat atattgaagc tgcgtatgga aaattgccca gctttttatt aggatgggcg
    45001 caaagcttga tttactttcc tgctaatatt gctgcattat cgattatctt tgcgacacaa
    45061 ttgacgaact tattacaatt atctaccgat tatcttttgt tgattgcagt gatcaccgct
    45121 gtttctgtga cagggttgaa tttgttaggg acaaaagtcg gtgcttctgt acaatcagtg
    45181 acgttgattg ttaaattaat accaattgct gtgattgtca tatggggatt attgacccca
    45241 ggacaaggaa ctgtccagtt atttccaatc gaagctggaa aagatgttac ttttgtcgaa
    45301 ggattgagca gtgcgttgtt agcaacgttg tttgcttatg acggctggtt aggtgtcggt
    45361 gcaatggcag gggaaatgaa acggccggaa aaagatttgc ctaaagcaat tattcttggt
    45421 ttgagttttg taacagtcgt ttatctattg atcaattttg tttttttgaa aactttgccg
    45481 attgatcatc ttgccggtaa tttgaatgca gcttctgaag catcagacgt catttttgga
    45541 ggaatcggtg gaaagctggt cactattggg atcttgatct cggtatacgg tgcattgaac
    45601 ggttatacac taactgggat ccgcgtgcct tatgcgatgg ctttagaaga cgagctacct
    45661 ttcagtaaac agctgacaaa gctttcaaag aagtttacgg ttccttatgt tcctgcggtt
    45721 ttccagttag cagtagcttg tattatgatg agccttggtt ctttcgactt tttaacagac
    45781 atgttgattt ttgtgatgtg gctattcagt ttactgattt ttatcggtgt ctttatttta
    45841 agaaaaaaag cgccggaatt gccacgtcca tataaagtac cactttatcc aatcgttccg
    45901 attattgcga ttctcggtgc tattttcatt ttaggtatga cgatgatgac gcaaacgaaa
    45961 ttagcattga tcggtatagg tgttaccttg ataggtatcc cagtctatta tcaaaaaaag
    46021 aaaaaacgct cagaagagta aaatatttca acaacagaca gaaaaagtac gaactaggtc
    46081 ctctagatct tcgtgctttt tctatttcaa taaaacaagt tcttctattt tgatttttgc
    46141 tacttctgca agtagtgctt atgtgctaaa gtaagaatga aaaggagaga taaacatgat
    46201 atttgattct catacccatt taaatgctga acagttcaat gaagatattc cagaaacgat
    46261 tcagcgagca caagaaatgg gggtaacgaa aatggcggtc gtgggcttcg atacgccaac
    46321 gattgaaaag tctttgcaat taagccatga ctatccaaat atatacagta ttatcggctg
    46381 gcatccgaca gaggctggca gttatacgaa agaaatcgaa aataaattac aagaacaatt
    46441 gactttacca aaggttgtag cattagggga aattggcttg gattatcatt ggatggaaga
    46501 cccgaaagaa gtccaagata aagtatttcg cagacagatt gctatcgcaa aagaaatgaa
    46561 cctaccaatc agtattcata ctagagaagc acttgaagac acgtatcaaa tcctaaaaga
    46621 agaagatgtt cgagatatcg gtggaatcat gcatagtttc agtggtgatt atgaatgggc
    46681 aaaacgattt cttgacttag ggatgcatat ttcatttagc ggtgtcgtca ctttcaaaaa
    46741 agcattagac gtccaagagg ctgcagcaaa tgtaccaatc gaacgattac ttgtggaaac
    46801 agatgcccct tatctggcac cagttccttt tagaggaaag cgaaatgaac caggctatac
    46861 tcgttataca gtagaaaaga ttgctgaact tcggaatctt ccgacagaag aagtggctgc
    46921 ccaaacatgg acaaatgcgc accgattatt tggtctaagc gaacatggat aagatgaaga
    46981 tccaagagat tatagtcgtt gaaggaaaag acgatacaag aaggctgcgg gaagtagttg
    47041 atgcagatac gatagaaaca atagggtctg caatcaatga agagatcctg atgcaaattg
    47101 aacatgccca agagactcgt ggagtgatcg tttttaccga tcctgatttt tcaggagaaa
    47161 aaataagaaa aatcattatg gaagctgttc ctcaggcaaa acatgctttt ttgccgcgca
    47221 cacaagctaa accaaagaaa aagggaagcc ttggtgtcga gcatgcaagt gatgctgcta
    47281 ttttagaagc attgaaaaag gtcgtgacgc cagacatttc ccaaacggct gtttctgaaa
    47341 tcactagaca agacctttta gactatggtt taatagctgg ggcacaagca aaagaaaaac
    47401 gagaaaaact aggtgacgag ttgcgcatcg gttacacgaa cggcaaacaa ttggaaaaac
    47461 gtttgaagat gtttcgtatt acgccgaaag aactcgccca agcaatgaaa atagtggagg
    47521 aacaacatga gtgaatatcg tgaaattgcg acaccctcta gaacaaaaga gattttattg
    47581 aaacatggtt tttcatttaa aaaaagttta ggacaaaatt ttctgactga accaaatatt
    47641 ttaaggaaaa tcgtagaaac tgcgcaaata gatgaacata cgaacgtgat cgaagttgga
    47701 ccaggaatcg gtgcattgac ggaacaatta gccaagcatg caaaacaagt cgtagcattt
    47761 gagatcgatg atcgtttgat ccctgtattg gctgatacga tgcaacccta tgacaatgtg
    47821 actattgtac atcaagatat tttaaagacc gatttgtcaa cagctgttag agaaacattt
    47881 catgaggagc ttccgttaaa agtcgtagcg aatttacctt actatattac gacaccgatc
    47941 atgatgcatt ttcttgaatc agatttggtt gtggatgaac tagtcgtcat gatgcaaaaa
    48001 gaagtagctg atcgtatctc tgctgaacca ggaacgaaag cttatggttc attatcgatt
    48061 gctgttcaat attatatgga agccagttta gcattcatcg taccaaaaac agtatttgtc
    48121 cctcagccaa atgtagattc agcgattttg aaactgacaa gaagagatat accggcagtc
    48181 gaagtgacag acgaaaaagc atttttccga ttgacaaaag cggcatttca gcaaagaaga
    48241 aaaacgcttt ggaataactt gcagcattcg tatggcaaag atgaccagac aaaagcatgg
    48301 ttagcaaaaa gcttggaaac agctggaatc gatccaaaac gtcgtgggga gactttgtca
    48361 ttacaagaat tcgccgcatt aagcaatgcg atgtcagaaa atatgcagta aaaaaagagg
    48421 ttgtgacaga agttgtgaaa aagctgtcct gcatcaagta ataagaacag ccaaacaaaa
    48481 atagttcctc atgtttttcg tttgtttggg cttattaccg cagatgcaag cttttgaaca
    48541 ccgtttaaga aagaggttgt gggcctgccg tttaactcta agtcacaagg aacaatttca
    48601 aaaaacagct tctcatgttt ttgagttagt tggtcttatt acttgatgca agcttttgac
    48661 cactattatg ccgaacaagg agatgtgaca caaattttgt cacatctcct atttttgttt
    48721 cttgatcaaa aaattcttat acttgatact cacactcatt ttgtatggat ttagaaaaga
    48781 atatgtgtct tgacagttat tagtaagtga gttatactaa gtcgacattt atgtgtcaag
    48841 acatattagg agagagaaaa aatgagaaaa aattcagttc gaaaactaac gatttctgct
    48901 ttattgattg ggatgggggt cattatccca atggtcatgc ctaaaatcat gattccacca
    48961 gcttccttta ctttggcgtc tcatgtgcca ttatttattg cgatgttttt tacaccagga
    49021 gttgcagtgg ctgttgcgct aggtacgaca tttggtttct ttttaacaac gccggttatc
    49081 atcgcattgc gagcattgtc acatcttgtg tttgcgttga ttggggcttg gtacttgcaa
    49141 aagcatccga gtatcgtttt aaaaaatgga cagtttactt ttgctaattg gcgtttccaa
    49201 gggttcaatt ttgtgatcgg tgtgattcat tctttagcag aaatgctagt agtcagcatc
    49261 ttttacttta ttggtaatat gcctgaaaca tattattctc aaggatattt ttatacagta
    49321 ttcatcttga tggggattgg tgggcttatc cacagtttag ttgattataa tattgcttat
    49381 tttatagcag gaacactcag caaatatttt gatatccccg tatttacggc agcaaaaaaa
    49441 gaaaatcgga aagagtcgat tcaagggtac gcgaagaaaa cgacatatta gacatgatct
    49501 ctcaaaaaaa aaactctcat ctagtaatgg ataataaatc ctctaagatg agagtttttt
    49561 gtcctaaaaa gagctgcacc aacatcttct ggcacagctc taacaggggg caatttatgg
    49621 aagtttgatg acttgttctg tttctttatc aaagaagtgg cctttgctga tgttgaaggc
    49681 aaggtcgact atttcgcctg gtttatggaa atctcttgca tctacttttg agatgaactc
    49741 agtagaacca gtttttgtgt aaagcatcgt ttcagctcca agtaattcgg aaacgacaac
    49801 ttctgatttc actacggctt caggtgaagc ttcaagggct acttgttcac tgtggatgtc
    49861 ttctggacga ataccgaaga taacttcttt tccttcataa cctttttcaa ctaatacttt
    49921 gttttttcct tcaggaatac gaagcttaag cccatgtcca tctgtgataa caccattttt
    49981 caatgtcaca ttaaagaagt tcatggcagg agatccaata aagccggcaa cgaacatatt
    50041 gacgggtgta tcataaactt ctttcggtgt accgatttgt tggataaatc cgtctttcat
    50101 gataacgatt cggtcagcca tagtcattgc ttctgtctga tcgtgagtaa catagatggt
    50161 cgttgtttca agacgctggt gaagtttggc aatctcagca cgcatggcta cacgtaattt
    50221 agcatctaaa tttgataatg gctcatccat taagaagact tttgcatccc gaacgattgc
    50281 ccgtcccaat gccacacgtt ggcgttgtcc accagataaa gcagctggtt ttcgtttcaa
    50341 gtattctgtc agacctaaga tctctgctgc attgtccaca cgttttttga tgtctgcttt
    50401 atcatattta cgtaatttca agccaaaagc catattatca aaaacagtca tatgaggata
    50461 caatgcgtag ttttggaaaa ccatggcaat atcacggtct ttaggtgcca cgtcattcat
    50521 gacttttccg ccgatattta gttctccttc agagatatct tccagtcccg cgatcattcg
    50581 caaagtagtt gactttccac aaccggaagg accaacaaaa acgataaatt cacggtcttt
    50641 gattgataga ttaaaatcag ttacagaata attttctgca ttgtcatatt ttttatatac
    50701 gtttttcaga gccatttcta ccataatacg ttccacactt tcttttttag ttttattaac
    50761 tatttaaagt ataaatgaaa gcgttaacta acttcaatgt catgttgaac aagaattttt
    50821 tctttttttt gtcaatgtgc tagttttaag ctttaataaa tatccataag aaataaaaac
    50881 tgatacactg gagtaaataa gtatgttaac aatatcaaaa ggagtgtctc ttatgaaaat
    50941 cgctttgatc gctcatgacc gaaaaaaacc tatgatggtg aaattagcaa cagcgtataa
    51001 aacaatattg gaaaaacatg aactttttgc taccgggacg actgggcaga ggatcacgga
    51061 agcaaccggc ttgccgatcc atcggtttaa atccggaccg ttaggcgggg atcagcaaat
    51121 tggagccatg atttcggagg atcagttaga tttggtgatt tttcttcgag acccgctggc
    51181 tgcacagccc catgaaccag atgtaacagc acttatccgt ttatctgatg tctatgagat
    51241 tccgttagct acgaatatcg gaacagctga ggtgctacta agaggactgg aagccggctt
    51301 cctagatttt cgaagaatcg tccatgaaat agacaagcat ccactttcat tttgatggat
    51361 aagcgtatgg aaaaataacg tttaatgttc gcctatatgt agctataaaa gctaaacaaa
    51421 ctgataatat gcgatataat acgaacgtat tggataatat aaacaataat attagttttt
    51481 cgtatttgca gtaaatgtga aaatatgcta tagtttctgt gggaaaagat cccaaaaata
    51541 atacagagta gaaaataaag cgttaagtgc taagaggatg ggatgttgcc tcttggacga
    51601 aggacgtaat gttcgcggtt ttattttcgc attcgctgca tgatacgatg tagcagctct
    51661 taaaggagat gctaaaaatg aagaaacacc ggttagacgc acgtatgatt gctattatgg
    51721 gcttattgat tgcattgatg gtcactttgt cccgactggt agcaatcgag accccattta
    51781 ttaaaatcag tgtcacattt attccacaag tgatcatggg cattcttttt ggtccttttt
    51841 ggtcagggat aggcgcagtt ttagctgatt tagtaggaat ggccctcttc tcgaaatctg
    51901 cattctttat tggatttaca ttgaatgcat ttattgaagg agcaatctac ggattctttt
    51961 tctatcgaaa agagatcact tggaaaaatg ccattctggc tacgcttagt gtcacgctga
    52021 tcatcaactt atttttgaca ccattatggc ttgcgttgat gtaccatgtg ccattgttca
    52081 gctgggtcgt ttgggcgccc cgcctgttaa aaacagtaat atggttaccg attcaatcaa
    52141 ttgccattta ttacgtagga cgtagtattc cttacaaaaa aattttaaga agtttagcga
    52201 tccacgctaa ataaaaaaca agcagtcttc ccatcccaga agactgcttg tttttattgt
    52261 gctgtgaatt gtgcttgata gagccgtcgg taataaccat ctttttgaag cagctcatca
    52321 tgggtgccca tttcgacaat agctccctga tccatcacta atatctggtc cgcatttttg
    52381 attgtggaca ggcgatgggc aatcacaaaa ctggtttttc cttccatcat tgctaagaag
    52441 gcttgttgga tttttttctc tgtcaatgta tcgactgagc tggtagcttc atctaagatc
    52501 aacatagggg gattactgat catcgttcga gcaatcgtca acagttggcg ttgtccatct
    52561 gatatcttta acccttgacc gccaatctta gtatctaatt tttccggcaa acgttctaca
    52621 aattcataca tataagaggc ttttagggca tcattgattt ctgcgtcact tgcttccgga
    52681 ttcccaaaac gaagattttc tcgcaatgta ctgtcaaata gccaagtatc ttgtaacacc
    52741 attccaaaac ttttacgtaa tgtatcacgt tggatagagc ggatgtcatg gtcatcgact
    52801 gtaattgttc cttttgttgt gtcataaaaa cgcatcagca aattaacaag tgtggatttt
    52861 ccggcccctg tttttcctac tatagcaatg gtttgacctg gataagcagt aaaattgaaa
    52921 tcttcgatca aacgctgctt ggggtcataa gaaaaagaaa catgatcaaa agagactttt
    52981 cctttgatat ttttgggttc caaggcatag gcatctggca aatcaggctt ttcttctggc
    53041 tgatcgatca aatcaaatgc tcgttctaga ccagaaaaag cggtttgcag ttgtgtcgtg
    53101 attccagaaa gttcgataaa tggtttagaa aactgacttg agtagatcgt aaagctggaa
    53161 atcacaccaa cagtgattga cgaaccactc ttcaatgcca ataggccgcc aactaaacca
    53221 atcgataaat aagcaaggtg atctacaaaa cgagaagacg ggtttgtcaa ggaagaagaa
    53281 aattgtgccc gttgtccttt ttcatataga tcagcattta gcagttcaaa ttgctgttga
    53341 ctagcttctt cttgctgaaa agctttcacg attttctggt taccgattcg ttcggtcaca
    53401 aagcccgaga tatccccaat aatcctttgc tgtctatcga aatttgtttg tgaagcacga
    53461 gcaacgatcc aactcacaag gaaaataatt ggtgtagaac aaagaacgac caatgtcaga
    53521 agtggactta gacgcatcat aaaaataaac gaaagaatga tgattgccac tccagaaaat
    53581 aattgattga aggccgcaga aattgcaatg gaaatattgt ccatatcatt tgtaaatcga
    53641 ctgacgatat ttccgtggga gttttgatca taataacgaa gtggcaatcg attcagatga
    53701 gcaaatgcat cttttcttaa ttttgcaacg gataagtaag ctaaccgatt gcttaacact
    53761 tggatgagcc attgactgac tacgttgatt aaaacgatac caccgaatag aataagtaaa
    53821 tggaacagtc gattgaagcg gacctgtcct tctccaatca tttgatcgat actttgacca
    53881 atttgtaacg tcatcacaac tgttgcaatc ccattgatga ttcctagtat cacagctagc
    53941 caaatgtctt ttgcataggc agtaaggtaa ggaatgaatc ggcggagcgt ctgcaaggat
    54001 aattttttta ctttcataac tattcttcct cctgtgatgc gacgatttcc tgatattctg
    54061 ctgattgagc aagtaattct tcatgggtac cctgagcagc aatcttacct tgatccatca
    54121 ctaagatatg atgtgcttct tgaatagagc ggacacgttg ggagataata atcactgtac
    54181 tgccaagata agtctgtagc gccttacgca aatccaagtc tgtttgataa tccaacgcac
    54241 ttaaagagtc atctaaaatc agtaatgctg gcttggcaat caaagctctt gcaatcgtca
    54301 gtcgctgttt ttgtccgcca gagaaatttt tcccattttc catgactttt gtatctaaac
    54361 catttggaag ctgacggaca aattcttctg cctgagcgat tttcagagct tcccaacatt
    54421 ctttttctgt ggcgtctttc ttaccccatt gaaggttttc acgaatagtc ccggtaaata
    54481 gtacagaagt ttggggaaca agagcaattt gctgacggag atgatccagc tgccaagaac
    54541 gaacatccat tccgtccatt ataactgtac cggaactgac atcatagaaa cgcggaatca
    54601 attgtgtcaa agtcgttttc ccgcttccgg ttggaccaat gattccaagg actgtatttc
    54661 gcttcagctg aaatgtaata ttttggagag aaagaccaga atcaggagta taacggaagt
    54721 caacatggtc aaaagcgata attgcttcag aagaaaaatc gggagtagta ctgacctcag
    54781 cttcaagaat cgaattttct gtgtctagca cctctttcac ccgatttcct gaagcttcgg
    54841 cacgtgtgaa gatcacgacg aggtttgaaa caacgatcag tgccaaaagc atttgattca
    54901 tataattgat caaagcaaga acttgtcctt gttgcaagct accaatattt actttgatcc
    54961 cgccaactgt cagcaaacag atgatcccga cattcatgat caaggttgta gcaggtgata
    55021 atagggcaga gatattggaa acacgtaaat aattgttcgc tagatcattt gtgcttttat
    55081 cgaacttctc tgtttctttt tttgtctgcg caaatgcgcg gatgacacga acaccgctaa
    55141 gattctgact aacgtgttca ttgagctgat ctagtttttc ttgcactttt tggtagagag
    55201 gaacggtttt tttgatgata aaaaataaaa tgattgagaa aataggcaat aatgctaaga
    55261 aaaacagacc tacttcccag tcgatcacaa aagccatgac cactgacccg atacttaaaa
    55321 acggtgctct gatcaataaa cgaatgacca ttgctaaagc tagctgaagc tgattgatgt
    55381 cgtttgtcat tcgggtgatc aaggtatctg ttccaaaatg attcaactcg ttgtgagaga
    55441 aagtattgat ttttttgatt agctgattac gtaactctgt accaaatcct tgtgaagcta
    55501 ctgaagcata gtattggcaa atgatagcac aaatcagacc aatcacagac atagcgacca
    55561 tccataagcc catttcaatg atttttcctc ggtcattcat ttttagtcca ttatcgatca
    55621 aggaagccat cattaaaggc aggacaagtt cgaagacagc ttcaagaaat ttgaagaacg
    55681 ggcccaaaat gatttgctta cgatagtctt ttgcataacg taataactga atcatatgat
    55741 tcctcctatt atttatttgt ccacaattga aaaaacaagt actaccacat tgtagcttag
    55801 gaaatttaga atgaaaagag aacaagcctt ttcataaatg aaagttttat tatgaagaag
    55861 ctttagaaat tgaatagact atttttttta aaaaaaagaa aatgagaaaa catgccagtc
    55921 tcttcattca taggaacgtc tattttactt aatttttcta taaatgaatt ctgcataaaa
    55981 aatatatcaa gtaaatgttt atagatgaaa ctctatttac ttctttttta atttgttctt
    56041 gcaatctttt ttgctacgta atttttgtaa aaaagtgggt tgagagaaat ctaattgatt
    56101 ttcaaagaag gagtatgaaa atgagaaaaa tatttattcg tttattgtgg gtactatctt
    56161 agaggaataa ataatagtgg agaaaactat ggtttggcgc agattctatc aggtttgatg
    56221 gaacgaagac aacctcccga catcaagtca aaagctactt gagattttga tctgaaaata
    56281 aaaaaagaaa acaaggtagg aacatcaatg tttctacctt gttttcgtaa tcaatgggaa
    56341 aaaactaaga gtggtgtacg taatcaataa aaaggatggt gacaacagta cctctttact
    56401 ctctgaaagc atcataactc gtttttcctc attatgccaa taaattgttg ttataccaca
    56461 tataaggatt tgtaatagct aaaaacagac aggaaagttg aaatctgtga atcttatttt
    56521 gtatggaagg atttatagaa cgcaaaaatc aagataaaga tgaataaaaa tcctgtttcg
    56581 gctatatatt gcgtatctac gccaataaaa cgagtttgtt ctgtcatagc catataaagc
    56641 aaaggcaaaa atacaactac agcgagataa gatccgatga tttctcgaaa agttttccag
    56701 gaagtatgtt tcctgttttt atatttatcc gatttcattg aatagtcata gcctccttat
    56761 tctttcatat gttgaaattc cagtataaaa actggaagga actgtacgtt ttttagaata
    56821 aaaattataa gggataagta ggctgctgtc tataataaga tatatttttc aattctttat
    56881 taaagatttt attgacaaaa tgaatccgtt ttctatgatg gaggaggggt gaataagttg
    56941 ttgaagaagg aaattttatg ttacttagag aaccagacag cctttttcga tttagaacat
    57001 atgaacgagg tctttacagc acaaaggtta gctgatcatt ttggggtaaa aagaaacaca
    57061 gtcagtcatt atttgaacca gttaaatgat gagcaactac tagtcaaaat caattctcga
    57121 ccagtgattt atttccacaa agaagctttt gaaaaacaat tttttaagtt acgcacgaat
    57181 ttttattttt ctatcgatga tctcaaagag gaacagcctt ttttcgcgca accaaaagac
    57241 ttattctctt ttatgatcgg atacgacgcc agtttgaaag aaagtatcga acaaatcaaa
    57301 acagctcttt actatccaga tggcggatta ccacttttga ttacaggcga aagtggcaca
    57361 ggtaaaagtt atttagttaa tttggtctat cagtattgtc tgcttcatga tctgctagaa
    57421 gattctgcac cattcatcac ttttaattgt gcacaatatg cagataatcc tgaacttttg
    57481 actagcaatt tgtttggaca tgttaaggga gcgtacactg gtgcagaaga aaataaaaaa
    57541 ggggcttttg aagcagcaga tggtgggatc ttgtttttag acgaggtaca tcgcttaaca
    57601 ccagaaggtc aggaaaaact gttcacctat cttgatcaag gtgtgattta tcgtatggga
    57661 gaacctaatt tgtcacgccg gatcaaaaca cgtctctttt ttgctacgac tgaagagatt
    57721 actagtcatt tcttaacaac tttcattcga agaataccta tccgaatcga actacctgca
    57781 cttaatcagc gtagtcgtaa tgaacggcta gaactgattt actctttttt tctcgaagaa
    57841 caaagaaaaa tggggagccc tttgtcagtc agtggaccag ctttgtcact tttaacaagt
    57901 cagaaattat ccggaaacat aggagagctg aaaaatatcg tcaaagtttc agcagcaaaa
    57961 gcatatgctg aacagcgtga acagcctgaa atccatgtca cgatccatca tttgcaaaaa
    58021 gaactacttg cgcagcctat tactaaaaat acagcacagc aaggaatcta tattacgcaa
    58081 gaccagacct tagagcaatt aatggagaag caacagcccg aacagcagcg aatcgttaaa
    58141 agttttgagc aaatcctaat tgatttcaag aaaaataact gtctgctata ttcttgcgaa
    58201 ggaaaattaa agcaagaagt gattcaatta tttgattttt tgctgtttga gaccagtaga
    58261 caagaaaaac acgagctgct ggtttattgg acacaatcta tccgagagac ctttcgacaa
    58321 atggaaactg cctatcaaat caaattcgat ggaaacagtg tctatgcctt gagttactat
    58381 ctctatcagc gaagcactat caaatggtta ccggaagaac atgatattat ccaactaatc
    58441 aaagaattag aacaacaagt ttctcagtct tatccatcta gttatcacta tgtccaacga
    58501 attctggaat taagtaagat caaattagat attgaagaca caagtatgga tcggatttta
    58561 ctgacgatct atctaaaaaa agcgaaatgg tcaaaagaaa aacgactgcc aaaagcgatg
    58621 attgctgctc acggttatgc aactgctagc agtatggcaa atgtagtaaa tcgtttatta
    58681 caagaggatc tatttgaatc atttgatatg ccactagatg tcacaccaca gcagattgct
    58741 tcagaaatcc ttgattattg cgaaaacagc gatgtttcaa atggattgat catattagta
    58801 gacatgggat ctctgaaaga aatccatcag ttttttaaaa aacagttatc cgtaccgctt
    58861 ttgattttga ataatgtgac gacaccttta gcaatcacag taggggaatg cctgcaaaaa
    58921 aatgtatcat tagaagagat agcagaagag actgttcgac agatccagcc agaatggcga
    58981 ctgctctatc cagaggaaaa caaacccaaa gcactcatta ctacttgctt cactggaatc
    59041 ggtacggcgg tccacttaag tgaactgcta gaaaaaagct tacctacggc ttgtcagttg
    59101 aaaatcatcc catatgaata tcagcaatta aaagataaga aaaacagtga cccattattt
    59161 tccatatacg aagtcgtagg aatgattggc accacagatc ctgatatcac caatatcgac
    59221 tatctttcat tagaagacct catctcgggg gaaaagatgt ctgtactagc tgaatggttg
    59281 gacactacta tgaatgcttc agagaaggaa atattcaatc agcgcatcat tcgtaatttt
    59341 tcattggaaa aagtactgga ttccgtgact attctagata cagagaaggt gatgggagaa
    59401 atcgatcatt ttatgagaga attagaggtg cagttgaatc gaagcatcag caatcccaaa
    59461 aaattagcgt tgtatgtcca tgtgagctgt ctcattgaac gattgatccg acaaatgcca
    59521 atcgaaacct atcaaggatt agagaaatgg aagcagtgtc aaaaagaagg gttatctgct
    59581 attaaatctg cgtttagtgt cattgaagag cattatagtg tcatgatccc caattctgag
    59641 attgcctata tctatgatat tttgagtgaa gatacagagt ttctctcgat agaagaagaa
    59701 ttttgaacat aagcaagttg ttgccactaa ttttggcatg caacttgctt ttttagtatg
    59761 tgtaagtgaa aagaggagat gaaaaagtgg atagagaaat tatcttagct tcccatggaa
    59821 aatttgcttc agggatatta gattcattag agctgatcta tgggaaaaat cattctatta
    59881 ctgtattcga ttgctatact gatgagaatt ttgatttagc ggaaacagta aggcagcttt
    59941 ttatgaggta caaagataaa gaaatcattg ttctgacgga tctttttggc ggaagtgtca
    60001 acaacgaatt cttacaatat atcaatcggg atcatgtcta tctcgttgcc ggattgaatt
    60061 tgccactatt gattgagcta gtatctcggt tggacgctga agtagagaca actgttttga
    60121 tccagcaggt gctaactgat tcaaaaaaaa tgatccagtt ttgtaacgag cggctcaatc
    60181 agaaaataga agaagacgaa ttttaggagg aagaaaaatg attgtattga caagagtcga
    60241 ccatcggtta ttacacggac aagtagcttt ttcatggaca caaacaatag gcgcagactg
    60301 tattttgatt gctaatgatg atgtacctac gaatgagata cgaaagacaa cgatcaaatt
    60361 agccaagcca caaggagtca aactagtgat caaatcaatt gatgactcga ttgccgcgtt
    60421 gaaaagcggg gtgacagata aatataagtt attcatcgta gtggaatcga tcgaggatgc
    60481 atataagctg gcagaagcgt atccagaaat caaaaccatc aacttaggag ggatcaaggc
    60541 aaaacctggt actcgcagca tcggaaaagc ggtaaatatt ttaccagaag aggaggaacg
    60601 cttgaaacga ttaattgaca aacaaataga agtagaaatc cgtcaagtac cagcagataa
    60661 aaaagtggat gtaagagaag ttttgtaaga aaggaagaac ctcaatgatt gtacaagcag
    60721 tcttattagg aattgttgca tttgtcgcac aatcagaata tgcactaggg acatcgttgc
    60781 tttctcgtcc gattgtgacg gggctgttta caggaatcgt gttaggtgat gtaaaaactg
    60841 ggatcattat gggcgcaact ttagagttag catttatcgg atcgttctca gtaggtgctt
    60901 cgattccacc tgatgttgtg accggtggga ttttagggac ggcttttgct attacagctg
    60961 gagccggtac agaaaccgcg cttttactag gtttgccgat tgctacgttg acattgatat
    61021 tgaaaaatat ttacttaggg cttttgattc caattatgaa ccataaagca gacaattatg
    61081 cagaagaagg aaattataaa ggagtcgagc atatgcactt gcttgccggt atcggtcttt
    61141 ccttgatgct tggtgttgtg gtaatggttt cttatatggt gggaagcaat acgatcggaa
    61201 atctattaaa tatgattcct gacttcgttc aaaaggggtt gtcagtagct acagggttga
    61261 ttccagctct tggttttgcg atgcttgctc gtttgctgat caacaaacaa gttgcaccat
    61321 attttttctt aggttttgct atagcttctt acttagagat tcctgtgacc ggagtagcta
    61381 tttttggtgc gattttagca gttgtggtag tcaatattat gaatgtccgt caactaccac
    61441 ttcaaacaac tgcaggggag gtagaagaag atgaagaatt ctgagatcaa aaacagcaaa
    61501 ataacgaaaa aagagctaaa tcacgtattt tggcgttctt ttcaaatgga gttttcttgg
    61561 aattatgaac gtcagatgaa tatggcttat gtttatgcaa tgattccgat tttgaaaaag
    61621 ttatatcagt cgaaagaaga aatggcagca gctttgaaac ggcatctaga gttttttaac
    61681 acgaccccac atatcgttac actgatttta ggaatcacgg ctgcaatgga ggaagaaaat
    61741 aaggatgatc ctgaatttga tgtgactgcg atcgatagta tcaaaacatc tttgatggga
    61801 cctcttgcag ggttaggaga ttctttcttt tggggaactt tgcgattgat tgccacaggt
    61861 gtgggtacct ctttagccat gcaaggaaat attttaggcc ctatcttgtt cattttgatt
    61921 ttcaatattc cgcacattct gtttcgctat ctagcaacag gttggggata tcgcttagga
    61981 acgggttttt tgaaaaagat ccaggcaaac ggtatgatgg aaagtttgac attaggcgcg
    62041 tctattattg gactgatggt cgttggagca atgactgcca cgatgatcac catcaatatt
    62101 cctttaaaaa tcggttcagg agaaaatgct gtgactgttc aaagtatttt tgatgatatc
    62161 gttccaaata tcttatgtct tggagcattt ggcatagtgt tttatctatt gaagaaagaa
    62221 gtgaaaccat taacgatctt gatcggacta gctttctttg gaatttttgg ttcgtggata
    62281 gggatttttt aaaaaaggag cagagaaaat gtttacgatg caagattata tctatgaaga
    62341 aaaggaagta ctaagtacga tcttgaaaaa gaatgatttt tcgacaagag aacatatgaa
    62401 aaaaacagtg aatttactga tcttagcaac gggttcatct tataacgctt gtttagcagc
    62461 gaagccagca ttggaatctt atggtgatct tactgtcgat attcaagaac ctttttattt
    62521 tttcaattat ggaaaacttt ctccttcaat cgatactgtg attgctgtgt cacaaagcgg
    62581 gaaaagtgct tctactgttg aagcagtaaa aatgatacaa aaacaagggt tacctgttgt
    62641 tgctatcaca aatgacgtgc aaagtccact tgctttagaa gctgcacaaa ttattgattt
    62701 aggtgccggg gtagaatcag taggcttcgt tacaaaaggc tattctgcga ctgttttaca
    62761 gttactactc ttagggatag gaattggaat aagtaaaaat aaaatcagca aaaaaataga
    62821 acaagactac atgcaacagt tgcgcaaaat aatcaaccat ttaccagcga ttattcaaaa
    62881 aacggaagaa ttttttgatg gatatcaaag tttatttcgt ttagcacagc gtttcgtcac
    62941 cattggatat ggtccaaact ggggaacagc taaagaagca gagacgaaat tgactgaaac
    63001 aatccgcgtt ccgtcacaag gatttgagtt agaagcttat atgcacggcc catacctgga
    63061 ggcagatgct tcgcatttgc tattctttat tgaaggggaa agtgtaaata aggaacgttc
    63121 gcaaaagttg caaagatata tgagtcggta cgttggagag actctcacca ttaccacaaa
    63181 aaaagcaaga aacgagaaaa cacttggatt agcaatagaa tgtgatgaat atctgtctgt
    63241 attagcgctt gtcgttccgt ttcaactatt cgcttataaa accgcagtag ctaaaggtat
    63301 tgacttgaac aaaaagattt ttgaagactt tgatacagtc ttgaaaagta aattataaga
    63361 ggtggaaatc atgctgaaat tcaatgaaga agaacaaatc aaagcaataa aaggcgcact
    63421 agctttacgt ccgcaagtag aagaaatcat cgataaactt tatgcggaaa aatttgacgc
    63481 tgtctattat ctaggaatcg gtggaacgta tgcttcctcg atgcaagctg tcacttatat
    63541 gaatgggaaa agcaacttgc ctgtctttgt acagcatgct gcagaatatt acactactgg
    63601 aaacaaaaga ttaacaaaag attctatcgt tattttgtcc tctgttaccg gtacaactca
    63661 agaagtagtg aaagcagtag aacaaatcaa gaaagtagga gcgacactga ttggatttat
    63721 cgataaagcg aacagtaagt tgtctcagct atgcgatttt gtggtcactt atccagctcc
    63781 tggaacagaa caaatcaaat tttttatggc agcagatcga ttgatgtatt tgaatggaga
    63841 attcgaagct tattcagaat actatgaaca gctcgaacgt tatttaccaa cagggttagt
    63901 ggaagcagag aaaaaagcag atgcatttgg cttatcattt gcagaaaaac atcgacgtga
    63961 tagtatgcat tattttattg gagcagggaa tcaatgggga gctgtttatt catatgccat
    64021 gtgttactgg gaagaacaaa gctggcttcc atcgaaatct atccatgctg ccgagtttct
    64081 tcacgggacg ttagagatcg tagaagaaac aaccccagtc acattatttt taggcgaaga
    64141 tgaacagaga gtgttatctg aacgtgtggc taaacttttg ccaaaaattt gcagcaatta
    64201 tacattgata gacacaaaag actatccagt agaaggtatc agtgaaaaat atcgcggacg
    64261 tgttttgtct ttcttattga tgcatgtagt gacacaacgc atcgatgctc atgtggagca
    64321 gttgaactgc catccattag agatacgccg ctactatcgt cagtttgatt attaggatag
    64381 actggataaa aagaatataa aaaataaaga gagcagcgat aactgctccc tttatttttt
    64441 taaaatattg gcatcaatta cgttataaaa cacatttttt gcattatcta cagttcaact
    64501 tataatctgt ttaatgggac atgtgggtgc caaccatttt ttgttatgca atagtactat
    64561 ttagttgttg catggatccg tagtaaaagt ccaagtacaa cgagttgcgc cagtttacat
    64621 agcgttttgt atccagaatg ttgactaaaa caaaagttcc tatgtcaacc gtcaacagag
    64681 acaatctgtc cgttgcagga cctgacagat ttagaaatgt tcaatctgtc tcttatgtat
    64741 tttaaatcaa tactcactag gagaagtttc ctaacctcct aatagtaatg ctggtagtaa
    64801 cattgtcaaa actgcttcct cttaggaaca agcaaagcat aacgagtgta aaaataaaat
    64861 gtagactatt gtaacatatc attgattatt tcaagtaaaa acgataaaag aagtaaacaa
    64921 acacttaaaa acaatggaaa ttagtcccaa ctttaagaaa tgtatactat aatggaaatt
    64981 atcaattatt tatttggagg aatatccatg aaacaaaaaa tcgcagttct tggtcctgga
    65041 tcttggggca ctgctttagc acaaacattg gcagaaaacg ggcatgatgt ccgtatttgg
    65101 ggaaatgtac ctgaacagat tgatgaaatc aataagtatc atacaaatca gcatttttta
    65161 cctgatttga cgatcccaga atcgattatc ggatataaag aattggcaga agcagtggat
    65221 aacgcagatg ctattttatt tgttgttcca acaaaagcga ttcgttcagt cgcacaggaa
    65281 cttattggta aaatgaatac taagccaatc attatacatg caagtaaagg actagaacaa
    65341 gatacgcata aacgaatctc agaagttttg gctgaagaaa ttccagaaga aaaaagacag
    65401 gcaattgttg tattatctgg tcctagccat gctgaggaag tggcagtaca tgatatcaca
    65461 acaattacag ctgcaagtat tgatcaaaaa gcagcagcct atgtacaaaa actgttcatg
    65521 aatgattatt tcaggattta tacaaataat gatgtgattg gcgtagaaac tggtgcagca
    65581 ctgaaaaata tcattgcaat tggtgccggc gctatccatg gattaggatt cggagatgat
    65641 gcaaaagcag caatcatgac tcgaggattg gcagaaatca gccgtcttgg tgtcgcgatg
    65701 ggtgccaatc ctctgacatt tatcggtttg agtggtgtgg gggacttgat cgttacttgt
    65761 acaagtgttc attctcgcaa ttggcgtgcc ggtaacttgt taggacaggg acataagctg
    65821 gaagaagttc tagaaaacat gggaatggtc gttgagggtg tggcaacgac aaaagcagca
    65881 gtagagctag ctcaacagct aggtgttgag atgccaatta ctcaaacaat ctataatgtt
    65941 ttgtataatg gagaagatat caaaaaagca gcaaaagaaa tcatgttacg tgacggaaaa
    66001 atggagaatg aattttctct tcgttaaata gatgatcaat agttaatcgt cgtttaggag
    66061 gaacagcaag tgaaggtcaa aaaagcagtc attcctgccg ctgggctagg aacacgtttt
    66121 ttgccggcaa caaaagccat ggcaaaagaa atgcttccaa tcgtggataa accaacgatc
    66181 cagtttattg tggaagaagc attggattcg ggaatcgaag acatcttgat cgtaacggga
    66241 aaagaaaaaa gacccattga agatcacttt gatgcaaata tcgaattgga aaacaatttg
    66301 cgggaaaagg aaaaaacaga attactcgct ttagttgaag aaacgactca agtcaatctt
    66361 cacttcatcc gtcaatctca tccaagagga ctgggggatg ccgtgcttca agcaaaagca
    66421 tttataggaa atgaaccgtt tgtcgtcatg ctgggggatg atttgatgaa agatgatatc
    66481 ccattgactc aacaattgat gatggattat gaagaaacac aagcttccgc tgttgccgtc
    66541 atgcgtgtac cagaaaatga aacatctaaa tacggaatta ttgatcctaa aacagatagc
    66601 gaaaagggtc gttgcagagt aaaagggttt gtagaaaaac ctgaaatggg aaaagcacca
    66661 agtaatttag ccattatcgg acgttatcta ctgactccta aaatatttga gatattagaa
    66721 actcaagaac caggagcagg aaacgagata cagctaacgg atgcacttca gactcttaac
    66781 cagacagagg cggtctatgc gagagagttt aaaggaaaaa gatacgacgt aggcgataag
    66841 ttaggatata tgaagacaaa tattgaatat ggacttcaac attcggaaat tgggacttca
    66901 ttaagtgcat atattatcca gttgagtaaa aagctaagaa cagaaagtta actggaaata
    66961 agtggcctgc tgagaatgaa aggctatttg ttattaaagc ggcagcttgt gcgtcatttg
    67021 cgcaactgtc gttttagttt tttgactcta gatcagttga gtcgtggaaa acgaaagata
    67081 gaaaaagact ttcgtgaata gattcagaaa atattatgct aatggtttaa ttttttttta
    67141 agttgtataa aagaaaatga ttacataaga gaaatgaaag ccaagccaga agattcatag
    67201 tagaataaaa aggcgaattt tttaattata aaaaaaggtg tgtgttcact atgggaaaat
    67261 tagtcgctgt tgcacagtcg ctgcttgata tactcaagtg gctgatggaa ggaagcaatt
    67321 ggatatttgt gttgccacta ttgcttatta gtctatttat catgtttcgc atggtcagaa
    67381 aaaaagaaac gtttctgatt tttatctggt atgcagcatc cgttggggtt gctaccttga
    67441 tggttgaatt ggcgttaggt agttgggaag cttgcgtatt tgctttattt tttgctgtac
    67501 tgtatctaat catttatatc ccatatatga aaagaaagtc tcggataggc agaaaaggta
    67561 gacatacaac tactttttct agtacagatt ctctcgaaca aagtagaaga acgagaagaa
    67621 gacggtaata tttagtaggt atacgcaaaa aaagataaaa taatggataa actattgaga
    67681 tgagagattt atttaattgg tggaaaaaag cttttttcac ttatataaaa gaatcttttt
    67741 taaaggaatg cttgttgtat cgggataagc cattcctttt tttatgttat ttatatatat
    67801 ataaatcata ccaatgtttt tttgtatttt cttgcttgca cttggataag agattactta
    67861 caataaattc agatagaaac agctgaataa aaaaaggctc cctgaccctt agttggcgct
    67921 aagaatcagg gaatgaccag tcacacacat acaccctgac cgatcatttt gccatagtca
    67981 atgcagtgca tcgacctaat ttattgtacc taatctaggg tgaaaattct acccctatgt
    68041 agatattttc catggtctgc acgttgtttt atttgctatg tcaaggtatt gggcgtattc
    68101 gttcaatgcc ttttttgtgt ttgaaacagc aaagaccaca tgtgttactg tctaactact
    68161 gtttttttat gtacttcctt agattaggca gctgtttcta ttcatgtcaa gtatagctag
    68221 gcgggagaga taaatgagtt tatgttattt tgactattat caccaattgg aagagaaatt
    68281 aaggatagaa gagccgctga tgcttcaagc tggcacttgg atcgcgaaac aaattaatca
    68341 aggtggtaga ttgcagatat atgctagccg cacactaagt ggtgtagcat ttgaattttg
    68401 ggatcaaacc ccggatcttg taccaagtat attgattgaa aatccagccg gaggtgtcta
    68461 tgaaacgcta gaaggtgcag gacaggcaat tattgatcag ctttctgtca aatcagaaga
    68521 catttttctt cttctttcga atgaaggaag aaacccggca atcatcgaac tagctcagtg
    68581 gatcaaagaa aatggtcatc cattaatcat tgttactgga tttgatttgt cacgaagtat
    68641 caaatcgcaa catagcagtg gtttgcgatt atttgaattt gctgatttgg ttttggacaa
    68701 ccacgccaat ttacatgatg cagtcttgac tttgccaaat ctagatccag cgatctgcgg
    68761 aacagcctct cttgcaacga tctttttgct gcagcaagtt ttgtatttta cagcaaaaca
    68821 gctagtccag gacacaagtg gaaaatagtt atccacatgt tgacaaagtt ccttaaaaaa
    68881 ataatgttcc acataaaaat ggagcgtttg aaaaaaagaa aacgattatt aatgaggatt
    68941 aacaacgact actttttttg ttttagttat tttaagatgg atcatctttg attttaagct
    69001 tgttttgttt aaagtttgtt atttttataa gttgtttcac agttatgaga aatgagttat
    69061 aagaatatgt agtgtcagaa aaataaaaag tagtggaaaa agagacaaga aagaatccat
    69121 atggattctt tcttgtctct taatacacgt tgatgaaaga gtcttcccca aaactcttta
    69181 caaagtaatt atagtacatt tgttatcatt attgcaatga agtttacctg atataacaaa
    69241 attgtccaac aggatacctt tttctaatag aaataaaata cacaaaaatt gaaggataga
    69301 taatggatat ttataagtgt ttattatttt ttttgcaatg aaattcaatt tttcaatgat
    69361 tgtaaaatga aaaaaacagg acgagatttt ctctaatcta aaaataaaaa aagaatttta
    69421 aggaaaaaca gagaaataaa atacttaata taaatggaaa gagaaaaaaa taatcataca
    69481 taggagaaaa aaaacaaaat agaaaaaagt gattttctaa taaattattc atgtggaaat
    69541 gtcattttta ctgtataatt catttgatta tccatttttt attcatcaaa attactgaaa
    69601 aaagaaagga agaaataaat ttgaagaaaa caaattcttc aggaaaaccg aaacgcgact
    69661 tcactaaatt atcgacaccc catacgtatg tcattatttt tggtgtagtc atctttgcat
    69721 ggatactgac ttttgtcgtt ccagcaggaa agttcagcac gcaagatatt gaatacaaag
    69781 atgcaaatgg cgaaacaagt actcgtactg ttttacgtca agattccttc cgttatgctt
    69841 acgagctgga taagtcgtat gtgtttgatc aattagaaga actgcaagat catccagcag
    69901 aacgtgaaaa actggatgtt ccggaaaaag gattggaaaa agtcattgct gacggagaaa
    69961 aaaatcttac gcaggaaaaa ctagatgaaa tctccttgac agatgatgtg ctttacgatc
    70021 agtacggcga aaatatctat gatacttcta aaaaattgca taaaacagcc aaaatatggg
    70081 gaacagatga ttttggcggc tttggtttct taaattttgt ttttgaagga ctagtatctg
    70141 gagataagta tggatctgct gtagggatcg ctgcattgat ccttgttgtt ggaggtgctt
    70201 ttggtattat tatgcgtacc ggagcgatcg acgcaggtat ctatgcgttt atcagtaaaa
    70261 ctaagggact ggagcgttta gctttaccgc tattattctt tgctttttca ttcggtggcg
    70321 ctacattcgg gatggcagaa gaggtaattc cattctcaat ggtgatggtt ccatttgtca
    70381 ttgcgttagg atatgactcg atcgtagcag taaccgtgac ttatgtcgca tctcaagtcg
    70441 gaaatgcgac ctcttggatg agcccgttta gcgtagcggt ggctcaaggg attgctggaa
    70501 tccccgtgtt gtctggtgcg acattccgat tgattatgtg ggtagttgtt actgcattag
    70561 ccgctggtta tatgatgata tatgcagaaa aaatccgtaa aaaaccagaa agttcgttga
    70621 cttacaaatc agatgattat ttccgttctc atatcaaaaa gacatctgat gaaaataaaa
    70681 aattcatgct tgggcataaa ttgatcttat tagagatgtt agttgtcctt gtctggatcg
    70741 tttggggcgt gactcaaaaa ggctattaca ttccagaaat cgcttctcaa ttctttgtga
    70801 tgggattagt tgctggaatc attgctgttc ttttcaaatt agatggaatg aaagtcaatg
    70861 acatcgcttc ttctttccaa tctggtgcag ctgatttagc tggtacagca atcgtagtag
    70921 gtatggccaa agggattctt cttgtcttgg gaggatctga tgcatctgtt ccttcagctt
    70981 tgaatacgat tttgcatggg atcgggacgg cgttgaccgg tgttccagct gtcattggtg
    71041 cttgggcgat gtacatcttc caaagtttgt tcaacttggt tgttacatca aattcaggac
    71101 aagcagcttt gactatgcca atcatggctc cactggcaga tttagtaggt gtatccagac
    71161 aagtagcagt tcttgcttat cagcttggtt caggttttat ggacgctttt acacccgtat
    71221 cagccagctt gattggtgtg ctaggtgttg cacggatcga atgggcaaaa tgggcaagat
    71281 tccaaatcaa gatgcaagga ttcctgtttg ttttaggaac tattttcatc atgattgcca
    71341 ttgcaatagg tctgcagtag tactggagac ctgtaaataa aaaagtaatc caaacagtag
    71401 ataaggactc caagaaccgt cattttacgg taaaatcaaa ggagtaaaga tcctatcgtt
    71461 tggattattt tttaagatcc tatcatcagt tatacttaaa gaaagaggaa aaatgtatga
    71521 aaatcattcg acaaattgaa gtgtttgcac cagattactt aggaaaaatg gatgtactga
    71581 ttgccggtgg gaagattttg gctgtagaag aacagctaga aggcggctac gaaggagtgg
    71641 aagtagaaga actttcaggt gagggaaaag tactaacccc gggtttcatt gactgtcatt
    71701 tccatatttt aggtggagga ggagaaggcg gttatcaaaa tcgaacgcca gaagtcacat
    71761 tgagccaatt gactacagct ggtgtaacga cagttgtcgg ttgtttggga acagacggag
    71821 aaggtagaga tatgactgcg ttgatcagca aagcgaaagg tctggaagca gaaggaatct
    71881 ccacttatgt atacgaaggt tcgtaccgat tgccggtaaa aacagtaaca gattctatca
    71941 tcaaagactt tttgacaatt gataaaatta tcggaatcgg agaaatcgca gtatccgatc
    72001 accgttcttc tcagccaagt tttgaagagt tcgctcgtgc agtagcagat gctcgtgtag
    72061 gaggcatgtt atccggaaaa gctgggatca tcaatgtcca cttaggcgga ggaaaaagaa
    72121 agctagagct attgacacga atcgtagaag aaacagaaat tccgatcaca caatttttgc
    72181 ctactcatgc aaatcgcaca ccagaattat ttgaagcttg cgtggcattt gccaaacgtg
    72241 gtggcacgat tgacttcact gctagcgaag atcctgattt ttgggagaag acagatggtg
    72301 aagttcgctt cagcaaagca ctgaaacgat tgatcgagga agatgtttct ttagataatt
    72361 tcacgatgac ctcagatgga caaggaagct tgccttattt tgatgaaaac aatcatttcc
    72421 tagggttagg agtaggaagt gccaaggcat tgctagtagg gatcaaagaa gctgtgcaaa
    72481 aagaaagtat ccctttggaa atcgccttac gagctataac cagtaatcca gcacgtatat
    72541 tgaaattgga taaaaaagga aaaatcgaaa ttggtgctga tgcagatctg tgtatcttgg
    72601 ataaagaaac gcttgatatt gatacagtta tcgctaaagg agaaataatg gtccaagaaa
    72661 aagaagtcaa agtatggggg actttcgaaa aaagttttta atcaacagct ctaactatct
    72721 tttttagaaa acgagcgttc tgtttgtctg tatctgttgt tgatgttacc ctgaaggtag
    72781 atcaataaac aaactaagag gaggaagcac aatggcagat ttaaaaggac gttctaaaga
    72841 tatgaaagat aaagtagtcg gtgaaggaaa agaagcatac ggcaaagcaa cagacgacaa
    72901 gagcaaagaa acagaaggga aagcacaatc actaggtgct gacatcaaag aaaaagctcg
    72961 aaatttaggc gacgaagtca aagacaagtt ttctcgaaaa gacgaaaaaa aataaaaacc
    73021 acttattact aattgaatca agcaaataaa aaatccgaac catatctgcg agacagatat
    73081 ggttcggatt ttttatttga tcattatcct gttttttaaa cttcgatttt ttgaaatttt
    73141 ttatttttta gttcaaagac ttcatcacag ctttttgcta cttcaatctc atgagtcacg
    73201 atgataatac agcgattttg ttcatgggcg atttcttgga aaagtttgac gatatcttgt
    73261 gaagttgttt catctagatt tccagtaggc tcatccgcta cgattagttg atgttcacag
    73321 cagatagcac gaacgatagc gactcgctgc tgctgacctc ccgaaagttt ggtcacctgt
    73381 ttttttgcta atatttcatc aattcctaca cgagccagtc gatctaaagc aacttgtcga
    73441 taattctctt gcttggtctt agtgatttcc attgctgcta tgacgttgtc tagagccgat
    73501 aaataaggaa gcaagttgta agcttggaaa ataatcgaga catcattttt acgataactt
    73561 cttaacccga ttttgttcag tgaacgatct tgatagtata cctttccttc ttttggtgca
    73621 tctagtccag aaataagcga aagaaaagtc gtttttccag aaccacttgc tcctaaaata
    73681 gcgtacattt ttccagcttc gaaattcagt tctacatctt tataaagcgc atcttgcgga
    73741 tcttgatacc aaaatcccaa ttgttctgtc cgtaacatca aattcctcct ttagtttaat
    73801 aggatttttc ttgggtttaa tcttaatatc cctatagaag ctaaaaagac agaaaacaga
    73861 ctgattccaa atgctactcc ggctaatagt cccaattgtg caggtttgac attgatttcc
    73921 aattcgctga cttgatcaga aacagcaaat ggattattcg tggttccttg ttgaccatcg
    73981 cgttgaccgc cttgttcttg tctgttacct ggcatttgtc caccgccagg agcttgctgg
    74041 ttttgtgtcg tggtttctgt ctgttggtca agtagctgct gtcccacggc attcgcgacg
    74101 acgtttccgc taagcgaagc aactcctaat gcaagaatca tacaaatagc cacttcggta
    74161 aacaattgga gaatgatttt acttctggat tctcctaaag atagcaagac gcctaactca
    74221 tgccgacgct cccgaatggt aatcataatg atcagagtaa gtatgataat accggctaca
    74281 gtcactagta aaacaacatt tttagaaaaa cttgccacgt tgtttaaagg ttccaacatt
    74341 gactgataca tggaatcatt tgattgtaag ctaaatgtat ctgtgtcgat cagcttctca
    74401 gcttctttga gaaactcatc cattttatct ggatcagata gagtgtaaat agcagaatct
    74461 atcgtgttat cgtcagatgt cccatttagt tcatttgcaa aagtgtaaga agtgtaaagt
    74521 gtattcgacg gattcatgaa gttgaatttc atacccatac tgccgcttgt ttcgctggat
    74581 tcataaattc ctttgatcgt catttcataa gtggtatctt catcttcagt actcgtgatt
    74641 gtgaaagtat ctccgactgc caggtcattt gtttctgcta gagtagaatc aatgactaca
    74701 ttgtttgtgc ctttgtcgct gtcatctatt ccttcaccat ccgtgatttt tgctgttcca
    74761 tcagaaaaat tactattttg tgcagttgct gacacaccac tgatttgaaa gtctgcttga
    74821 gtcatttgcg gattcccgcc cattcctcca gcaggttcac cgcctgcatc agtagtttct
    74881 gaactgtctt cacttgaatc agaactagtg atggcagtta ttccatcttt tgccatagct
    74941 gaggcggaac tttcaaagga ataactcttt acattatcta attcagctat tttttccgcg
    75001 tccgttaagg aaactggtgt aagagaaaaa ctgcctggat ctggacgttc ttcagtggta
    75061 gaaccgcttg aagaagtttg ttcctgtttt ttaaatgaag cttctcgatt ggcacttaaa
    75121 gtcactgttg ctccaacttc tttttgtgct tgattcgctg cttcttctgc agcgcttcga
    75181 atcgtgaggc cagctagcac aaaaataaga atggctgtga acacggcaaa caataacaat
    75241 gaacgtcccc attttacttt tgtacttttc catgcacgtt tcataaaatt catattttgc
    75301 atccctccta gtagatgcat ttgataatag acaacctatc ttaaagctag cttaaatctt
    75361 atgctgtttg cacaccatca acatgaggtt ctgtatatat aaaaagtcac tatagttatt
    75421 gcaaaaaatg tggtaaaatg aaaaaagtat gtttcaaacc gacgaagaag aaatgaaaga
    75481 ggaatagcaa aagaaatcct agatgctaca gagggatttt tacgtgcata gttgttctaa
    75541 caattgctga tactagcgat ttagtttatt tgttgtataa taatggggaa cagctgaata
    75601 cttatataag tattctggct atagcgtttc gcaaaagatc cattttgtta atgaagtata
    75661 tccaaaataa aatgcccatc caactgtcag aacgcggatg tgctggtaat tttcctgctg
    75721 attctccata agttgagaaa tagtgatttt gcatatgctt cattggaatg gctcatatat
    75781 ttagataaag aagaaaatcg acatctttaa acttggatgt cataagaaga ggtgaagttt
    75841 gtgagtacca ttaaaattat cccattaggc ggcgttcgtg aaaatggaaa aaacatgtat
    75901 gtcgcagaag tgggcgagga tatttttatt ttagattgtg ggctaaaata tcctgaaaat
    75961 gagttgttgg ggatcgacgt cgtaatccct gattttacgt atttagaaga aaacattgat
    76021 cgtgtagctg gtgtcttttt aacacatgga catgcagatg cgatcggggc acttccttac
    76081 ttgttgtcaa aaatttctgt accagtattc gggacagagt tgacgatcga gttagcaaaa
    76141 ttgaatgtca gtcgtaatga agcagccaaa ggatttaagg atttccatgt ggtagatgag
    76201 catacagaaa tagactttgg tgaaacagta gtgagctttt tccgtaccac tcatacgata
    76261 ccagattcag tggggatcaa tctgaaaaca aaagaaggta gtatcgttta tacgggagat
    76321 tttaaatttg accaaacggc tatcccaatg tatcaaacag attatgcacg attggcggaa
    76381 atcggcaaag aaggagtctt agccttacta agtgaatcgg caaatgcaga aaatcctcag
    76441 cctgtagctt ctgaagccca aatagcagat gaagtatttg atacgatcaa atattgggaa
    76501 gggcgtatca tcgtcgcttg tgtagcaagt aatttgcaac gagtgcaaca agtattggat
    76561 gcagcagaaa aagcacaacg aaaagttgtc ttgactggtc aagatttcga acgaattatt
    76621 cgcacagcga tgcgtttaga aaaacttcaa ttaccaagtg aagatctgct tgttacgttg
    76681 aaagacatga aaaactatga tccagaagaa ctgatcattt tagaaactgg ccgaatgggt
    76741 gaacccatca agtctctgca aaaaatggca aacggtacac accgtaatgt caagattgaa
    76801 gaaggagatt tggtttatat cactactacg ccaagcatcg cgatggaaac catcgtggcg
    76861 aaaacggaag atatcattta tcgagctggt ggaacagtga agttgatctc tgagaatatg
    76921 cgcgtttctg gccatgccaa tcctaatgac ttgcaattaa tgatcaattt gatgaaacca
    76981 acatattttg tgccagttca aggagagtat cgtgaattag ctgctcatgc agatttggct
    77041 catgcagtag ggatgccata caaaaatatc tatattactg gacgcggaga cgtgctggaa
    77101 tataagaaca agcgtatgag tgttgcagga actacaagtg cagaaaatgt aatgattgat
    77161 ggattaggca taggtgatat cggaaacatt gttttacgtg atcgaaaaat cttgtcagaa
    77221 gacgggattt tcgtagcggt tgtcactatc agtcggcgag aaaagaaaat catttcaaaa
    77281 cctcaaatta cttcacgggg attcgtttac gtaaaagcta gccgtgatct gatgaaagaa
    77341 agcagcaata tgattgaaac aatcgttgag aaacatttag aaagcaatga ttttgagtgg
    77401 agcaaattaa agcaagacat ccgagatcaa ttaggccgtt acttatttga acaaacaaaa
    77461 cgccgcccag tgatcttgcc agtcattatg gaagctactc aacgtcgaaa taaaaaataa
    77521 acaaaaagag taagatgaac ctctctatag agtgctcgtc ttgctctttt tttgcgaaaa
    77581 acaaataatt tttgaataca gcatccctcg ctttataata aacgatagaa taaagggagt
    77641 gaatcaatga tgagtcaaac aaaagtcgaa cgttatttag aagaacaaaa gatcagctat
    77701 caaccacttg attttagtca tgtggtagaa gaatctttca cagaagaact acaaaaaaga
    77761 gggattgatc cagctttgat atgtaaaact ctcgtagtga aaggaaacaa aactggggtg
    77821 atcatcgcat tgattccttt gaacgatcac ttagattaca aaaaaacgag acaagtgacg
    77881 aaagatcgta aagttggttt tcctggaatg gattttgtat taatgcatac aggatatccc
    77941 cacggagcaa acacccctat tggaataaaa ctcgcacatc ctgattattg ttttttagca
    78001 gacagttctt taaaagaaaa agaagaagta attgtgtcaa gcggtgaaat cgggagaagc
    78061 cttcggataa aagtagccga tttagaaaag atcgtccatc ctatttacgc tgatttaatt
    78121 agttaaggga cgagaagaga agctaagcag agcagagacc tcaaacttga gattatatct
    78181 gcttggtact tggtgcatcc tgtattatct gttacaattg ctttgtacat actgtactat
    78241 caatccaatg aaaatatatt tagcagctat attttttcat tgatgtgcaa gtgatgaaat
    78301 cgtttttaat aaaaaagata cagagaaaac gcgaggtgta aaatatgaaa attacgtatc
    78361 atggacattc ctgtttaaca attgaaatgg aaaatggcca acgcgtgatg attgacccgt
    78421 ttattacagg aaatccattg acagacttaa ctgcagaaga agtaaagaca gattggttgc
    78481 tgattactca tggtcatagt gaccacatag gagatatgat tcctattgca aaagaaaatc
    78541 aagccacaat tatcagtatt gttgagattg ctgattatgc gaacagcaga ggagtagatt
    78601 cattcggtat gaatatcggt ggaaaacatg cgtttccatt cggcgtggta aaattcgtac
    78661 atgcacagca tagttcaagc tatgaagtag acggtatcgt tcagtatatg ggcgagccta
    78721 gcggaattat tattcaagca gaaggaaaaa cgatttatca tgcaggggat actgcttatt
    78781 tcagtgatct aggattgctt gcagaagaat tcgatattga tgtcgctttc ttgccgattg
    78841 gcgataacta tacgatgggg ccagaagatg cagcaaaggc tgcgcaaaca attcgtgcca
    78901 agaaagtagt tccaatccat tacaatactt tccctgtcat tgaacaagat cccgaatctt
    78961 ttgtagagtt actggaagat agtgaaggaa aaataatgag cgtctcggaa acgctggaag
    79021 tgtaggcaga aaatggcgac aaaacatgat ttgattttag aatatattga aagtttacct
    79081 gttggcaatc gaatttctgt aagaagcatc gcaaaagaat tgaatgtcag tgaaggaaca
    79141 gcgtaccgtg caatcaaaga tgcagaaaat gtcggactag tttcaacaat tcaacgagta
    79201 gggaccatcc gtatcgaacg caaattaaaa aaacatattg aacgtttgac atttggcgag
    79261 gtcgtcagga tcattgaagg ggacgtttta ggcggggcgg caggattaga caaggtcttg
    79321 aataaattcg tcatcggcgc gatgactaaa catgccatgg aacgctatat tacgccagga
    79381 tcactaatga tcgtcggcaa ccgggcggaa gtccaaaaat tagcattgga agatggcgcc
    79441 gcagtattga tcacaggagg attcaatacg actgctgaga ttgcaaagct agctgatgat
    79501 cttgaaatgc cgatcttacg cacctcttat gatacattta cagtcgcaac catgatcaac
    79561 cgagcgttaa gcgaccaatt gatcaaaaaa gatatcatgc ttgtcagtga tatctatatg
    79621 ccagctgaaa agactcatta tttgcagcag acagatacga tttctgatta tcagcgtttg
    79681 tcagaagaaa cgcagcattc gcgttttcca gtcgtcaacc gccatcatcg tttgatgggg
    79741 attgttacgg caaaagatgt tttagggaaa tcgccaaacc agatcatcga tcgggtgatg
    79801 acgaaagaac caatcagtgt aaagaaaaca atgagtattg cctctgttag ccatcaaatg
    79861 atctgggatg ggctagaagt catgccggtc gtttccgatg acttgacatt ggaaggcttg
    79921 attacccggc aagatgtaat gaaagcgatg cagcttgtcc agcgacaacc gcagattgca
    79981 gatacgattt cggatcagat atctggaaat atccatacga ttgatactga ccgtgaagga
    80041 aatcgtttgg aaaaccctaa gttcaaattc gtagtagcac cacaaatggt caatggcgtt
    80101 ggaaccattt cttttggcgt acttagcgaa atcatttctg atgtcgcaca aaaaacaatg
    80161 gtgatgaacc aaaaacgaaa tatcttgatt gaacaagtga acctacatta tttgcggctg
    80221 atccaattgg aaagcgaatt agacattcgt ccacgtgtat tggaaatcgg cagacgttcc
    80281 gctaaactgg atatcgaagt gtttattgaa aacaccatcg tttccaaagc aatcgttgtt
    80341 tgtcaagtaa tggaacgttc ttagaaagca ggagtgaaat gacagtacag caagaaatag
    80401 tagatacaat aaaaaaatac gataaaatca ttatccacag gcatttgcgc cctgatcctg
    80461 atgcattagg atcacaagta ggattagccg aactattacg ggaaagtttc ccagaaaaag
    80521 aaatacgtca agtaggtgaa acgattgaag ggcttcgctt tttagcagaa atgcaagaag
    80581 ttgaagatgt cttctaccaa ggagcgctag tcatcgtgac tgatacagct aattcaccca
    80641 gaatcagtga tcaaagatat cagttggcag aaaaactgat caaaatcgac catcatccca
    80701 atgatgaccc ttatggagat cttgtgtggg taaatacaaa agcaagtagc tgtagtgaga
    80761 tgattgcaga atttgctttg atgtttcctg aatctttaaa gatgaacgtt aaggctgcac
    80821 ggttacttta tgcaggaatc gtcggagata cagggcgctt tttgtatccc tccacgacgt
    80881 cccgtacatt agagattgct tcgatattga gaaattatcc atttgatgca agtgctttga
    80941 acagagagat tgaacaaatg ccgatgaaag tcgctaaact ttccggttat ctttatcaaa
    81001 atatccaggt ggatgaaaat ggtgcaggaa gaataatcct tccgcaagaa attcttgata
    81061 aatatggaat cgatgattca gagacagctt cgatcgtttc acttcctgga gtgattgacg
    81121 aagtgctggc ttgggggatt tttgttcagc agccttcagg gtattaccgc gtacgtttac
    81181 gttctaaggg gccgatcatc aatgaattgg ctaaacgcca tcatggagga ggccatccat
    81241 tagcaagtgg tgcgaatgca aaagatttag cagaagtaga ggaaatctat aaagagatcc
    81301 aagatatatg ccaatcgtat aagagcagaa aaacagaatg atacttcgtt cgaaaacgtg
    81361 ccttttgtag taaaaatcac aaatgtatct tttcaagatc ttctttttcc gttacaatag
    81421 tgctcactaa agattttaaa ggagaaagaa gatgacatta ccaaattgcc cagaatgtgg
    81481 ctcagagtac acatatgaag atcgaggctt gttgatttgc ccagaatgcg ggaacgaatg
    81541 gaacaaagaa gaacaagaaa ctgtcataga agacggatta gtggtattag atgcaaatgg
    81601 aaaccgtctg ttagagggcg atagcgtgac agtgattaaa gacttgaaag taaaaggtgc
    81661 gtcaggtgcc attaaacaag gaacaaaagt caagaacatc cgtttagtag aaggcgatca
    81721 taatatcgat tgcaaggtag aaggatttgg accgatgaaa ctgaaatcgg aatttgtgaa
    81781 aaagaattaa agaatattca aggtcttttc acattctttt cctactacta atgataaaat
    81841 aaagtaaacg aaaaggagtg aaacgaaaat gtatggttat ggaatgtatg gttttttaga
    81901 tccgacattt cttttggtca ttcttggatt agttatttcc ggaattgcgt cagcgtacgt
    81961 caatagtact ttccgaaaat acgatcaagt gagaagcaaa aacaatgtga ctggtacaca
    82021 agcagcacaa tatatattac aaagtcaaca gataaataat gtcggtgttc aacaaattgc
    82081 cggagatctc acagataact acaattcagg taataagatg ttgagtttgt ctcaagcaac
    82141 tgcacagtct acttcagttg ctgcgatagg tgtagcagct catgaatgcg gacatgcggt
    82201 acaagatgct tcgggttatg tcccattgaa gattcgtgca gcacttgttc cagcagctaa
    82261 ctttggttcg atgatttcgt tccccttgat tatggtaggt gtattgctta gctggaactc
    82321 tacgttaatc aatatcggga ttttcgcttt ttctttagca ttacttttcc aattggtgac
    82381 attaccagtc gaatttaacg cgtctcggcg agcaatccaa attttgagtg aaggcggact
    82441 actgacggaa gaagaagtac cgatggcaag acacgtatta tttgcagcag cactgactta
    82501 tgttgcagca gcgctttcga cattcctgca gctgttgcgc ttgatcttat tgttcggcgg
    82561 caaccgaaga gattaaaata aagaagttgt gaaatcagcg ctttgatctg agctaatacc
    82621 gagagttagc tgattgaata ccatttattt ggaataagag gatgtgacaa gaattttgtc
    82681 acatcctctt tgttttgttc tcataacctt ttttcatata cagttcatga accgctttta
    82741 ttaacttgcc aaataacact gtattgtgcg ttgtatccag atagaaagtc tccgtttcat
    82801 ctgaaatttt ctcatgctga tctgtaatga tcaaatcagc atgttctgaa tatgcggtaa
    82861 ttttaacagc atctttgcga aataactgct gcaaatggct ttgaagatga taatttcctg
    82921 taaactgttt ggttatctgc aaatggatga gtaactgctc tttcgtttct gtttgtagta
    82981 agtgttggat caattgacta aggtattgac tgatttggtt tctttcccca ttttttgaaa
    83041 aaattgtatc gattttttct cttaatttct tttcctgtat aaaagaacta gaatgattgg
    83101 acgtggcttc tggaaagcaa agtgtagaaa aactactgct ggattcaccc aacagttcga
    83161 aaaaaacaac tgccaacaca agaaaataaa aataaattgg tattttattt tctaaatggt
    83221 tgagaggaaa ctgttgagtt aagtaagtca tcaattgacc gacttgtcga caaataaggt
    83281 ttttgcttgt ggaaaataaa aaaccaatct cctgtttttg tcgaaaagag atttgatttg
    83341 gaaaaaaaca atagaaaaaa taattaaagt aggctctctc tgtttctgtc tcttcacaag
    83401 ggcgactcac tgaaaaagaa gtaaagtatt ctgaataatc atgtgtatgc tgcaataagt
    83461 ccatcaattc agtgatttca gaagaagttt ttggaaaata tgcctgttgt ttgtttcgta
    83521 atatgaataa agttaacagc aagtagatat ttttttcttg ttttgaaatt ttttctattt
    83581 gctcatctgt actgttcatt tttagtgcat ttaattcaag tgaggaaaat ggccaatcgt
    83641 tacctccaaa tgtatctgaa agaaaaaagt aaagatagag acggatagat aactcatttc
    83701 cttcaagagt acagcaattt tttacagata ggatccgtaa atggaatttt tttaaggaat
    83761 gattgagctg ttttgtcagt ttttcgagat aggagggcga tatataaagt tgttcaagta
    83821 aatatttttt tggtacagca gtttgtggat aattgattag taacatcaaa tagttaaaac
    83881 gattggattc ttttaggtag cataatttta acttagaaaa aacagctaac tttttagttt
    83941 gatcggtttc tttggtttgg atctctcctt tatgattaga ataaataaat tcatcaatca
    84001 ataaaaattg cttgagtgat acatttattt ttcggatcag ttctttgatt gtccgttttg
    84061 gaatatgtaa gtcattggat aattcttgta aagaacaatt atttttttga atgaccattt
    84121 gtagaacaag taactctttt tttcttgctt caattagcat aaatacctcc tttttattct
    84181 gtttttgtat atagttagac aaaaactgtg agtggaaagt catttcagtc tgtgttattc
    84241 tcacagagtg tcgccttctt ttttatataa cgttatttaa tttttttgtt accttgttta
    84301 ttctattgtt tatttcctag ggtattttgt caagatattc ttgtttttaa ggcggaaaaa
    84361 ttgattttta atggatataa ctaaatatgt tttgataatt atcaataata tttttagaat
    84421 tatttatgtt atttatttat gggtagatga aaagagacgg aggtaagaat gatggggaga
    84481 gtaacaaatt atagtaaaga atatttgctg ttcaaaagta tggtatacgt ggaagaatat
    84541 ggaatgaagt caattactgc aagagagtta gcagagttct gcggttgttc tacatacccg
    84601 atttatacac atttcaaatc aatcagcggg ttaaaagaga agatattaga agaaatcact
    84661 gtttattttg aaaactactt agctgaatgc agttccgatg atgttttaag cattgtctac
    84721 ttattgaaag attttttttc tatccatgaa agtattcgtg aaatcattgc aaaatctgat
    84781 ttagacatgg attcgctatt taagcggcca tttttctcat atgtcaaagg tcacacgaag
    84841 atcaaagaag aaaagtcgct tgaattggta tggcttaatg cattgggaag tttgcgctca
    84901 gatgattctt ctcaagattt tcttgaaatg atgaacgctg tttgggataa aaacgaggtg
    84961 acggatgaat acttggaaaa tatcttaaag gaacagtcac cttaggcagc aacatgaaaa
    85021 agtagatcag ccacctttat ttttcgtaaa aaagattgta aaatgtctaa cgaaacattg
    85081 gaatgaagga ggaagcgaca acgttaccac agcaatttat caaaaaatat cgtcttcttt
    85141 taggcgaaga agcatccgat tttttttctg cgcttgaaca aggaagcgtg aaaaaaggat
    85201 ttcggtggaa tccactaaaa ccggcaggat tggacatggt ccaaacttac catagcgaag
    85261 aattacaacc cgctccctac agcaatgagg gatttcttgg cactgtcaat ggaaagtctt
    85321 tcctccatca agctgggtat gaatatagcc aagaaccaag tgcaatgatc gttggaacag
    85381 ctgctgcagc aaaacccggt gaaaaagttt tggatttgtg tgcggctccc ggtggtaaat
    85441 caacccaatt agctgctcaa atgaagggga aagggttatt agtgacgaat gagatctttc
    85501 cgaaacgtgc gaagatttta tcagaaaata tagaacgatg gggagtttcg aacgcaatag
    85561 tgacaaatca tgcacccgca gaacttgtcc ctcatttttc gggctttttt gatcggatcg
    85621 tggttgatgc tccttgttca ggagaaggaa tgttccgaaa agatccaaat gcaataaaag
    85681 agtggacaga agaatctccg ctatactgtc aaaaacgtca gcaagagatt ttgtcttcag
    85741 caataaaaat gctaaaaaat aaaggacaac tgatttattc gacttgtacg tttgcaccag
    85801 aagaaaatga agagatcatt agctggcttg tagaaaatta tccagtaacg attgaggaga
    85861 ttcctttgac tcaatccgtt agttcaggac gttctgaatg gggaagcgta gctggtttgg
    85921 aaaaaacaat acgtatatgg cctcataaag atcagggtga aggacatttt gttgcaaagc
    85981 tgacttttca tggacaaaat cagatgcata aagaaaagaa gacacgaaaa aaaagtaaag
    86041 tgcaaatgac aaaagagcag gaaaaactct ggacggagtt ttcaaatgat tttcattatg
    86101 aagctactgg aagactttta gtgttcaacg accatctttg ggaagttcct gagttagccc
    86161 cttctctcga tggtttaaaa gtcgtacgta caggtttgca tttaggagat ttcaaaaaga
    86221 atcgatttga acctagctat gcattagcgc ttgctacaaa aaagatagag aatatacctt
    86281 gcttgccgat cactcaaaag gaatggcaat cttacacagc aggagaaaca tttcaacgtg
    86341 atgggaatca aggatgggtt ttgctagtat tagataagat acctgtcgga tttgggaaac
    86401 aagtaaaagg aacagtaaag aactttttcc ctaaaggatt gagatttcac tgagtggatt
    86461 agttcgttta tttttttgtc tatgctatga tggagataga taaaaaggag ctgatactta
    86521 tgaaaacatc aacaaaagta acaatcggat taagcgtagc agccgctgcc agtgtagcga
    86581 cagcagtcgt tgtatcggga aaagtaatgg aaaagatcca tcatatgact actcggacga
    86641 aagtaaaaaa attcgtctat gacaaatttg atggaaatga aaaattacta gaaatcgtag
    86701 atggtctttc agatagtgac ttggattctt tgatgggaat gttagcaaaa atcaaatcag
    86761 gaaaaaagaa aatctctgtt tatggtgatt caatcaaaga ttcaaccgaa gatgtaaaag
    86821 accggctaat gcattttgtt gaaaaaatga tgtaagagaa actagctttt gaacactatt
    86881 cattcgaaat aaggggttgt gacaaaatta ttgtcacaac ccctttaatc tatctttaat
    86941 tatgttcatg aagcaataaa agatagcaaa acagtaaatc gttggctttt tttagattga
    87001 aaccagactg ttcttgaaat ttttcgattc gatattttag agtattacga tgaagaaaca
    87061 gtgtttttgc agcagagctg acattgccta attcattcca taattcttga atgatcactt
    87121 ccatttcatt ttgtttgatc agttctatgt aacttttgat caacttacta tcttttacag
    87181 tatcttttgt atagtaatgt aaagccacat cttgcataga aaaagtacgg ctgtgagtat
    87241 aaagattgtt ttgctctgtt aaaaaaattt ttctttcttc agcaaacaaa gggacgaggt
    87301 cggtgccagg tgaatggaaa gaaccaacga atacagacgt tgtcgtatca aaatcagcat
    87361 ctaaagatag aaaaataccg ttgatttcag tagcatcaag ataatcacgg tttatttgtt
    87421 cgactaagag cgcatctgtg tctgtataaa aaaagaaatc agcagaatag cgaaataatt
    87481 ccaaaatagt atcttgccat tcttttttta agaattctcc ttttgattcg acgtgaagct
    87541 ggatcaaacg aaagcttttt tcttgaacac aagaagcatc tttaaaaaga tagtgatacc
    87601 atgggtgttt tttttgatcg ttgattacag ggaataacgc tttcaaaagg ctggtttctt
    87661 gttgagataa tgaatcttgt ttgatccaga taaaagcatc atcaattgca aaagaaagga
    87721 tatccgcttc tgatgctgga gagttttttt tctgtgcttg tgggtaaaga gcaagtaatt
    87781 tatccatttt catcttgttc acctcttgta tttattttac catagaaaaa aaagttagtt
    87841 acagcctttt tatcatatgc taaagtaaaa caagaaaaaa caaaggcagg gaagggtaat
    87901 tggtaaatac aaatcttgat gcagtagaaa aagaaaaatg gatgcgcctt gcattggcag
    87961 aagcaaagaa agcagaaatg cttcatgaag ttccgattgg agcagtggtt gtattggatg
    88021 gaaaagtgat tggaagagga tataacctta gagaaaccac gcaagatgct actacacatg
    88081 cagaaatgct tgcaatcaag gaagcctgtg aaaaagtggg aagctggcgc ttggaagatg
    88141 ctgcactttt tgttacctta gagccttgtc ctatgtgcag cggcgcgatg attttgtctc
    88201 gtgtagcaga agtttatttc ggcgcgtatg atccaaaagg cggaacagcc ggtaccttga
    88261 tgaatctttt ggaggacgag cggtttaacc accaagcata tgtagaaggt ggcattttag
    88321 aagacgaatg tgggatgatt ttgactgact ttttccgaaa gctccgccag cgaaaaaaga
    88381 aattaaaaaa agactggtca acgaatgaaa aataaggtat actattcttt gccgaaaggc
    88441 taggacaatg gtgggcttgt gaagcgtgtc aggtctggaa ggaagcagca ctaagcaggt
    88501 tccgccatgt gtctgattat aatgaaacga caacagactt tcgggtctgt tttttttatt
    88561 tttatagtac tgtaaaaatg aatgttcctg attttttagc cagactgatt tatcgaatat
    88621 tgtacttata caatttgctt caaggcagga aaaactctga aatagagctt gtttcaatgg
    88681 aagaaaaagc tgcctatggt atgataaaga taaagagagg cgagagggta catggaaaaa
    88741 atagtgattt tacatacgaa tgatctgcat tctcatttag aaaattggcc aaggatcaga
    88801 aggtttttgg atcaacgtaa acgagaaaac gaaaagaaag aaaaaacgac aacgattgca
    88861 gtagatctag gtgattttgt ggatcgttgg catccattgt cagaagcaac gaatggacag
    88921 gaaaatatct tgctgatgaa tgaagttggt tatgatgcag cgacgatagg aaacaatgaa
    88981 ggcgtaggaa attccaaaga agagttgaat catttatacg atcatgctga gtttgatatc
    89041 atcctggata acttattcga taaaaatacg ctccagccac cggcatggac gaaaccatat
    89101 aaaatcatta caacgaaaca ccagacgaaa atcggactaa ttgcatttac tgctccattt
    89161 ccgcttactt ataatccgaa tggctgggac atacggaatc cttatgatat tttgccagaa
    89221 ttagtcgaag atttacgttc acaagtggat gttttagttt tgatgagtca tctcgggatt
    89281 caggatgatt tccaaattgc aaaagaaata ccagcaattg atgttatttt aggatcgcac
    89341 acccatcatt tattcagaga aggtcacgta atcaatgatg tccaaatagc agccgctgga
    89401 aagtacgggc agtatgtcgg tgaagtccat ttaaccatcg atgaagagaa aaaaatcctt
    89461 aagcattcag ccaaagccat ccctaccgaa acaatgacag cttttacaga agatgaacaa
    89521 gaaataaata gttatctaga acgtgggcat gaattattaa aagaaaaaga agtagcagat
    89581 ttgccatttt ctctgagtct agatatcttc aatgagcatt cgtttatcca agtagccttt
    89641 gaggcggtga aagaacgagg aaagacggaa gcagcaatat taaacagtgg tctgttttta
    89701 actgaaattc caaaagggcg ggtcaatcag gatcagcttc acactgcgtt gccgcatccg
    89761 atgcacttgt taaatgtcac attgggtgga aatgatctga tccgcttagt tttagaaata
    89821 gaaaaaaatc gtaacttttt acgtaactat cctatgaagg gaatgggatt tcgcggtaag
    89881 atttttgggc agatggtcta taatggaatc acatatgatt ctattaacca tcaagtcttt
    89941 tggaagaaca agccaatcga tctgaataaa aattatactt ttactaccgt agatcatttg
    90001 atgtttgttc cattttttcc aacgattgag attgctggaa aaaatgaatt tttgttccct
    90061 gaatttatcc gaagtgtggt aggagattac ttgaaagctc actacccaat caaataaaaa
    90121 caaggtataa taaaaaagat aggtggtgaa cgcatgtctg caaaacaaaa tgaacagcag
    90181 aacgttgagc ataaaacaga aattgctaag aaaaaatcat cagctgaaca ggaaacaaca
    90241 gtcaccgaag aactgacagc tgctttggaa gaaatcgttg aggagcctaa agcagaaaaa
    90301 gtcaaaggcg agctagtgac actgttagat gacagtaatt ttttgatagg tgaaagacat
    90361 tatcggcttg tgtccgatta tcgtgaagga tttaatgcag aaaagcttgg agaacgttac
    90421 agtgatgtac tagcccgata tgattatatc gtaggagatt ggggttatga acaactacgc
    90481 ctaaaaggat ttttccaagc ggataatcga cgggcgcatc cagatcagcg aatcgattcc
    90541 ttggaagact atctttacga atattgcaat tttggttgtg cgtattttgt catcgagaga
    90601 atcggcggta aaaaagaaaa gacaactcag cgccgaaaaa agaaaaaaaa ccataatcgt
    90661 gcgtatatcg atgagaaaaa aggaccagtc gcatctaatc gcaaaaaacc ggttattaaa
    90721 aatcgaaaaa cagagtcagc aaaaacctct gaaaaagtaa aaaaacaaga acaacctaaa
    90781 caagtagaaa aaacaaaaac agcatttacg atcagaaaaa gggaagagta gtggatgaat
    90841 ggactataaa ggatatttaa ttgatttaga cggaacgatt tatcgtggga cacaacccat
    90901 accggccggt aaacgatttg tggaagaatt gcaaaaaaga aaattacctt tcttgtttgt
    90961 taccaataac acgactaagt caccagaaac agtagctaat cgtctagcag atgagtttga
    91021 cattcatgta gctccagaga cagtctacac agctactttg gcaacaatcg attttatgaa
    91081 agcagatgga aaagggaaaa aagtctatgt tatcggagaa gcaggattga ttgacttgat
    91141 tttagctgcc ggatttacat gggaagaaga ggctcctgac tatgtagtgg taggcttaga
    91201 taattatctg acctatgaaa aagtagttaa agcaacactt gctattcaaa aaggtgctac
    91261 tttcattgga acgaacccag ataagaatat acctactgaa cgcggccttc ttcctggagc
    91321 agggtcagtc atctcttttg tagagacagc aacccaaacg ccgccgatct acatcggaaa
    91381 accagaagcc atcattatgg ataaagccgt tgaagtatta gggctgcaaa aagaagaagt
    91441 aatcatggtt ggagataact atgaaacaga tatccaagct gggatacgca ataatataga
    91501 tactttgctc gttttatcag gttttacaaa agaagaagat gtacctgggt tgcctatccc
    91561 agctacctat gtgaaacaat cactggatga atggagcttc taatatgaaa aattcgagat
    91621 ggcagtggat ggaatatgct ggattgttca gcctatttct gacactgatc agtctggcag
    91681 ttggtgtgac gatcaacttt cgaccactat acgtatttga tatcggacat ttgcaaattt
    91741 tggattatac ttctttagat caagagacgt tactgaaaaa ttttgatcac ctaatgaatt
    91801 atctcaataa tcccttcaaa accatcctca gcttgccaga tttcccagtt tctgctagcg
    91861 gagcccatca cttttatgaa gtgaaaattt tgtttttagt ggattatgct gtgtttttca
    91921 tcactttgat cccgagtatt ttgtttatca aatatttgca aaagaatgat cggctttggc
    91981 ggttgattcg tccgtttcaa atcggcatgt tactgccagt tgttttcggt tttttcatga
    92041 tgataggatt tgatcgcttt tttatccttt ttcatgaaac gtttttcaac aacgatgact
    92101 ggttattcga tcccgttact gatccaatca tcaatgtact tccagaagaa tttttcatgc
    92161 atagctttat cttatttttt gtattattag aattattttt tgctgttttt cttttcttag
    92221 gaaaaaatag cttgaaacaa acaaaaaaga aagaactcgt ctaaatagac gttttctttc
    92281 tttttttgtt gaattattga gtaaggcgac ttcttttttc tggttctttg tgtgctaatc
    92341 gactggcagc agcagcggcg atcgctccga cgatatcatc taagaaggta tggacatgaa
    92401 cgccatcgtg gctgtttagt tcttttaaaa taccaggttt caccttgtcg atataaccat
    92461 aattcgtaaa gccgatcgta ccgtaaacat tcacgattga caaggctagg atctcatcga
    92521 taccgtaaag gccttcgtca tcttcgataa tatgttgcaa cggactcatc aattttttct
    92581 tttctgctaa tatatctaat tggattccag tgataatggc gttatgtact tcacgctttg
    92641 ttagcacgct gttgacactt tcagtacaat ccgccaaagt caaatcagaa atatagtctt
    92701 tttgtaaaaa catgacaagt tgtgcgatat cttctacagt tacgccacgt tccttcaata
    92761 gttctcttgc cttttcttct aaagtctcag ttttgacgac catattattg ctcccccttt
    92821 attttttctt tctctatttc atgttaacgg aacatgaaaa aaatgcaaga aactgctttc
    92881 gggtttaact tgaaatgcaa agagatataa aaaatcaact aggacgaaga tttttatcgt
    92941 ataagcttgt gctgtgacca ggctgagttc gttcctttgg attaatatag tgtaaagcgt
    93001 tgttcactgc agtaggtgct tcaccgagcc cagtagcaat cagtttcact tttccttcat
    93061 aggtacagat gtcaccagct gcataaacgc ctggaataga agtagacata tctgatttta
    93121 cagtaatggc atttctggta ctatcaagtc cccaagaaga aagatgttct aaattagaag
    93181 agaatccata attgacgatc agagaatcaa tcatcaaatc aatcgtctcg tcacttttca
    93241 ctttttttaa ccggatatct gtcagttccc cattattgcc tgataatcca tcgatgagat
    93301 agggagtaag caagttgaca gatgaagatt tcaagcgtga tacactatgt tcgtgcgcac
    93361 gaaattccgg gcgacgatga atcaagtaaa cttcgcttgc aataggctct aacatcaacg
    93421 tccaatcgat agcagaatca ccacctccag caatagcgac tttttttcca gcatacttca
    93481 tcaaatcatt cacgaaataa tccaatccgt ggttttcaaa tgattcagca ttatctaaat
    93541 tcaattttct tggctggaat gaaccatttc ctaaagctaa aatgactgct ttggaataat
    93601 ggatgccttt atttgtagta atctcgataa cttcgtcttc acgagtaagc gagagaactt
    93661 cttcttttaa atggaatgta tggttaaaag tagttaattg tttttctaat tgatcgatta
    93721 attcacttgc ttttattgct ggatacccag gaatatcgta aatatatttt tcgggataca
    93781 aagttgctaa ttgaccacca agttgaggta gactgtcaat gatttttgtt ttagcttggc
    93841 gcattcctgc gtaaaaagcg gcaaacatcc ctacaggacc tgcaccgatg attgtaatgt
    93901 catagatttc cataaaaatt cctccctttt cacactatag cagaatttaa ttgagaatgc
    93961 ttctcaaaaa tgtttgaatt cgaaatcgaa acggtaagtt atagaatgta tctagtgatg
    94021 aaaaataaaa gaaaacaaat ctagtatttt tacgagaggt taggtattat gttattatta
    94081 ttatgaagta tgcaaat
//
LOCUS       DAXLPY010000003        81904 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.003, whole genome shotgun sequence.
ACCESSION   DAXLPY010000003 DAXLPY010000000
VERSION     DAXLPY010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 81904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.003"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..313
                     /locus_tag="ACF3UF_000227"
     CDS             <1..313
                     /locus_tag="ACF3UF_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HFD3670388.1"
                     /translation="LVLYPREILYIESIKGLKNQVMVKTTTEDKLVNTSLKQLKTELE
                     KYAYFLLLKSYCINLSQLQKIDSAHYVLEFFNGDSLLVGRKIFEKTKERFHDFQKTAS
                     S"
     gene            complement(399..1157)
                     /locus_tag="ACF3UF_000228"
     CDS             complement(399..1157)
                     /locus_tag="ACF3UF_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFD3670389.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(1154..1618)
                     /locus_tag="ACF3UF_000229"
                     /pseudo
     CDS             complement(1154..1618)
                     /locus_tag="ACF3UF_000229"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            complement(1637..2134)
                     /locus_tag="ACF3UF_000230"
     CDS             complement(1637..2134)
                     /locus_tag="ACF3UF_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HFD3670390.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            complement(2202..5369)
                     /locus_tag="ACF3UF_000231"
     CDS             complement(2202..5369)
                     /locus_tag="ACF3UF_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFD3670391.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(5593..6477)
                     /locus_tag="ACF3UF_000232"
     CDS             complement(5593..6477)
                     /locus_tag="ACF3UF_000232"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3670392.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(6572..7009)
                     /locus_tag="ACF3UF_000233"
     CDS             complement(6572..7009)
                     /locus_tag="ACF3UF_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670393.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(7226..8137)
                     /locus_tag="ACF3UF_000234"
     CDS             complement(7226..8137)
                     /locus_tag="ACF3UF_000234"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3670394.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(8594..9022)
                     /locus_tag="ACF3UF_000235"
     CDS             complement(8594..9022)
                     /locus_tag="ACF3UF_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670395.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(9050..9688)
                     /locus_tag="ACF3UF_000236"
     CDS             complement(9050..9688)
                     /locus_tag="ACF3UF_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670396.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(9692..11728)
                     /locus_tag="ACF3UF_000237"
     CDS             complement(9692..11728)
                     /locus_tag="ACF3UF_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFD3670397.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            11854..12519
                     /locus_tag="ACF3UF_000238"
     CDS             11854..12519
                     /locus_tag="ACF3UF_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3670398.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(13959..18356)
                     /locus_tag="ACF3UF_000239"
     CDS             complement(13959..18356)
                     /locus_tag="ACF3UF_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019788126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HFD3670399.1"
                     /translation="MTTALKSKAKYFDYLPKYGSKLEHFLGIPNLVDAINTYRVTVNQ
                     IPNEVAIGTRRYSEVAARKIASNVGIDQQSMKYVDVLRELRVRNNITPTIADLFHKLR
                     KYGNVAAHENGIIPVSEAVESLVTLDTLLRVFARNLSGDKSLNPKEEITDEMFVITYN
                     TFDRKLIYIQSAKDADGTWKMYQGLEKIGDASVPENYEADFTPNSEYLREYASRRIKQ
                     YMTTAGVPFVLHWAQLAVNKKNQFFRDHDVHEVLKRSGYNPQTIGEDDTGKPNEWFSV
                     TVDVAKKAIQAVKDGKGSLDSEKDDFDEFKINFRPEQKDAIEQTKTVFKTKDEMLWNA
                     KMRFGKTLSSLQVIKESQYKKVLIMTHRPVVSDGWFTDFKKIFTDGSYIYGSKQDGEK
                     IQNLVDTEKPFIYFASIQDLRGSEWAGGKAGDKNYEFLAIDWDFIIIDEAHEGNETEL
                     ANNVKAKLRKEHTKVLELSGTPFNLFDKYDEDNIFTWDYTMEQEAKEKWSVEHPNEPN
                     PYEGLPKVSMFTFEIPNKFDYFDENKAFNFREFFRVKEDDETKLLHEGDVRKFLDYIT
                     TNDEKTNFPFSKPEFRENLRHTLWLMPGVKEANAFERVLETHPIFKDYNIANVVKTGD
                     SEHASDSDLELVRKAIGNPAKSKTITLTVRKLTTGVNVPEWTGVFFLSNTESPTSYLQ
                     AAFRAQTPFNHAELGIKKNCYIFDFAPDRALKIMSGSVGLTSKKGKVNSSEQKKKLER
                     MLNFLPILGKQGNVMKEFSVDRMLTALKKAYAEKAVRTGFEDSSLYNDNLLNLDQADL
                     TKFEDLKKIVGSSKPTKVKDFIVSDNGMSEEEYEKASRAEKKPKRQRTKEEQEAIDRA
                     KRLREQRNKMISILRGVSIRIPMMIYGMDIDIKDDVTIEMFLNLVDEASWNEFMPEGL
                     SKGRFREFIEYYDADVFVEAGRIIRRRAKSYDELDVIERTRKIGELFSTFKNPDKETV
                     LTPWRVVNMHLGNTIGGLSFFDEEYQNSTENGQPIVRWRKTDCTDDIFKENRKILEIN
                     SKTGLYPLYAATSMYYVQLLKQSDINAGRVDSEAIWEKVLSEQIFVISKTPMAKTITK
                     RTLIGYNAWKVNVEYSSELVTSMKRSINDGLTNLKGVYKNVKFDVIIGNPPYQEKDGG
                     SGASATPLYNLFVETSVKLSERYVSMITPSKWFAGGKGLDKYRDFMLNSSSLKVMVDI
                     VNGKEIFPNTSIGGGVSYFLWDKKYNGLTQYTNQHDGVSNTQERKMNEFPVFVRYNEA
                     ISAIHKIGEHASVGDFVISRNPFGLPTKIRGEEVQDSRNSIKVISSGGVGFVPLEDIT
                     KGQDMVGKYKVISSSLTSEHAGEPNKNGMFKVISTNRVIKPNEVVTDSYLVLFSADTE
                     TEAINYLKYLRTRFYRFLLLQAVTSIHLSKDKFMFIPVQDFTSGSDINWNVGIEEVDM
                     QLFKKYSFDASEILFIDQTIVPILHEEYY"
     gene            complement(18334..19119)
                     /locus_tag="ACF3UF_000240"
     CDS             complement(18334..19119)
                     /locus_tag="ACF3UF_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylase"
                     /protein_id="HFD3670400.1"
                     /translation="MVEDMVMVEEEQGRLIKSKKRVQKHGEVFTPQRTVKDMLDLPGI
                     KEACEELQTTFLEPSAGEGAFLVEVLTRKMAMVAREYNESLEQYENYSLLALSTLYGV
                     ELLEDNAQTCVMNMFQVFNDLYREQSKKHGTAMKRKVQDSAKTLISRNIKQGDFLTKR
                     TPDDNPIIFSEWTPKTLRKGQKKITVNRTEYSLEDIYSGVTREFGEAYSALPVFEQLD
                     LFSFDDEVDEEVSNDPILRYVAMPITEVYKEEMEEIDDDSVEI"
     gene            complement(20875..21651)
                     /locus_tag="ACF3UF_000241"
     CDS             complement(20875..21651)
                     /locus_tag="ACF3UF_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670401.1"
                     /translation="MMKKNYLKTGIFLVIGTILVIQLSGCRNKDKDFYGYWSGTAEKI
                     PVDYNFKITKDRVIELQKNGEMVDFKYTLRHKKFDSTTFRSIMISKDELVKAIPELKE
                     TTGISNITFMPIDGEKDKLTVLVNLDEHLSTATLYRTTKDESPIGKVEKKNDTISRQT
                     VDKKIDTFIKTYAAIPPTWKLVNEDKGITINTDTEIPTDAQSLSDLLANLTGVSNAVS
                     EQVGKDIPLRLLENGKKDYSVVFKNGKVTDYNEIFEKVIE"
     gene            complement(21852..22178)
                     /locus_tag="ACF3UF_000242"
     CDS             complement(21852..22178)
                     /locus_tag="ACF3UF_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670402.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(22224..22586)
                     /locus_tag="ACF3UF_000243"
     CDS             complement(22224..22586)
                     /locus_tag="ACF3UF_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFD3670403.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADEVKKSTEQTFS
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(22623..22838)
                     /locus_tag="ACF3UF_000244"
     CDS             complement(22623..22838)
                     /locus_tag="ACF3UF_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3670404.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            22964..23299
                     /locus_tag="ACF3UF_000245"
     CDS             22964..23299
                     /locus_tag="ACF3UF_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3670405.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(23375..25372)
                     /locus_tag="ACF3UF_000246"
     CDS             complement(23375..25372)
                     /locus_tag="ACF3UF_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670406.1"
                     /translation="METPMINIPINVDKERLLEKPVIEDEKKRIRKRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNKSEEFLETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKALSINLVHNSAFAIQKSIRYSENLEKFKIVFLLKEAITDYSKMIAVYEYLKKI
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHDDHNPSASIFTSKTGHSIFYCHSSNCGISENFIGVVMLILEKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMEDKLFRTINNYLEEMRRVYDALLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKWNKLLSFMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLKKVHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNFRSELSKEKQLILDEAHEVLQDLSWQGTYLMTEKELINTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELIASGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(25470..25745)
                     /locus_tag="ACF3UF_000247"
     CDS             complement(25470..25745)
                     /locus_tag="ACF3UF_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3670407.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMEQYKG"
     gene            25980..26714
                     /locus_tag="ACF3UF_000248"
     CDS             25980..26714
                     /locus_tag="ACF3UF_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3670408.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIIEEFDNNILLLTSSIEEQLEEMIDEGIHSQVEDMNYPEEAVNEIIDN
                     INKLKQTISSIGKKYTKKKMKGGDTI"
     gene            26753..27895
                     /locus_tag="ACF3UF_000249"
     CDS             26753..27895
                     /locus_tag="ACF3UF_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3670409.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(27990..29381)
                     /gene="sufB"
                     /locus_tag="ACF3UF_000250"
     CDS             complement(27990..29381)
                     /gene="sufB"
                     /locus_tag="ACF3UF_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFD3670410.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKAVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(29386..29856)
                     /gene="sufU"
                     /locus_tag="ACF3UF_000251"
     CDS             complement(29386..29856)
                     /gene="sufU"
                     /locus_tag="ACF3UF_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFD3670411.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(29843..31078)
                     /locus_tag="ACF3UF_000252"
     CDS             complement(29843..31078)
                     /locus_tag="ACF3UF_000252"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFD3670412.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(31075..32361)
                     /gene="sufD"
                     /locus_tag="ACF3UF_000253"
     CDS             complement(31075..32361)
                     /gene="sufD"
                     /locus_tag="ACF3UF_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFD3670413.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(32374..33147)
                     /gene="sufC"
                     /locus_tag="ACF3UF_000254"
     CDS             complement(32374..33147)
                     /gene="sufC"
                     /locus_tag="ACF3UF_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFD3670414.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(33344..34192)
                     /locus_tag="ACF3UF_000255"
     CDS             complement(33344..34192)
                     /locus_tag="ACF3UF_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD3670415.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(34216..34902)
                     /locus_tag="ACF3UF_000256"
     CDS             complement(34216..34902)
                     /locus_tag="ACF3UF_000256"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFD3670416.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(34895..35929)
                     /locus_tag="ACF3UF_000257"
     CDS             complement(34895..35929)
                     /locus_tag="ACF3UF_000257"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFD3670417.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(35992..36248)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(36324..36662)
                     /locus_tag="ACF3UF_000258"
     CDS             complement(36324..36662)
                     /locus_tag="ACF3UF_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFD3670418.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(36664..37020)
                     /locus_tag="ACF3UF_000259"
     CDS             complement(36664..37020)
                     /locus_tag="ACF3UF_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFD3670419.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(37026..38213)
                     /locus_tag="ACF3UF_000260"
     CDS             complement(37026..38213)
                     /locus_tag="ACF3UF_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFD3670420.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(38404..39249)
                     /locus_tag="ACF3UF_000261"
     CDS             complement(38404..39249)
                     /locus_tag="ACF3UF_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3670421.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            39483..40448
                     /locus_tag="ACF3UF_000262"
     CDS             39483..40448
                     /locus_tag="ACF3UF_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFD3670422.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            40825..41868
                     /locus_tag="ACF3UF_000263"
     CDS             40825..41868
                     /locus_tag="ACF3UF_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFD3670423.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(41930..42394)
                     /locus_tag="ACF3UF_000264"
     CDS             complement(41930..42394)
                     /locus_tag="ACF3UF_000264"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFD3670424.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            42640..43587
                     /locus_tag="ACF3UF_000265"
     CDS             42640..43587
                     /locus_tag="ACF3UF_000265"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3670425.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(43798..45870)
                     /locus_tag="ACF3UF_000266"
     CDS             complement(43798..45870)
                     /locus_tag="ACF3UF_000266"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFD3670426.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(45803..46180)
                     /locus_tag="ACF3UF_000267"
     CDS             complement(45803..46180)
                     /locus_tag="ACF3UF_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFD3670427.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(46309..46869)
                     /locus_tag="ACF3UF_000268"
     CDS             complement(46309..46869)
                     /locus_tag="ACF3UF_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3670428.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            47019..48311
                     /locus_tag="ACF3UF_000269"
     CDS             47019..48311
                     /locus_tag="ACF3UF_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFD3670429.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(48371..49489)
                     /locus_tag="ACF3UF_000270"
     CDS             complement(48371..49489)
                     /locus_tag="ACF3UF_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFD3670430.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(49503..50924)
                     /gene="arcD"
                     /locus_tag="ACF3UF_000271"
     CDS             complement(49503..50924)
                     /gene="arcD"
                     /locus_tag="ACF3UF_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFD3670431.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(51170..52291)
                     /gene="mnmA"
                     /locus_tag="ACF3UF_000272"
     CDS             complement(51170..52291)
                     /gene="mnmA"
                     /locus_tag="ACF3UF_000272"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFD3670432.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLIYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            52695..53294
                     /locus_tag="ACF3UF_000273"
     CDS             52695..53294
                     /locus_tag="ACF3UF_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3670433.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(53432..54718)
                     /gene="efmA"
                     /locus_tag="ACF3UF_000274"
     CDS             complement(53432..54718)
                     /gene="efmA"
                     /locus_tag="ACF3UF_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFD3670434.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(54989..55333)
                     /locus_tag="ACF3UF_000275"
     CDS             complement(54989..55333)
                     /locus_tag="ACF3UF_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFD3670435.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(55470..56615)
                     /locus_tag="ACF3UF_000276"
     CDS             complement(55470..56615)
                     /locus_tag="ACF3UF_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFD3670436.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(56795..57769)
                     /locus_tag="ACF3UF_000277"
     CDS             complement(56795..57769)
                     /locus_tag="ACF3UF_000277"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFD3670437.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(57849..58724)
                     /locus_tag="ACF3UF_000278"
     CDS             complement(57849..58724)
                     /locus_tag="ACF3UF_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFD3670438.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            58854..60761
                     /locus_tag="ACF3UF_000279"
     CDS             58854..60761
                     /locus_tag="ACF3UF_000279"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFD3670439.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(61302..64580)
                     /locus_tag="ACF3UF_000280"
     CDS             complement(61302..64580)
                     /locus_tag="ACF3UF_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFD3670440.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(64851..65396)
                     /locus_tag="ACF3UF_000281"
     CDS             complement(64851..65396)
                     /locus_tag="ACF3UF_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFD3670441.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(65408..66100)
                     /locus_tag="ACF3UF_000282"
     CDS             complement(65408..66100)
                     /locus_tag="ACF3UF_000282"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFD3670442.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(66119..66403)
                     /gene="macP"
                     /locus_tag="ACF3UF_000283"
     CDS             complement(66119..66403)
                     /gene="macP"
                     /locus_tag="ACF3UF_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFD3670443.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(66416..66979)
                     /locus_tag="ACF3UF_000284"
     CDS             complement(66416..66979)
                     /locus_tag="ACF3UF_000284"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFD3670444.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            67207..67869
                     /locus_tag="ACF3UF_000285"
     CDS             67207..67869
                     /locus_tag="ACF3UF_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFD3670445.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            67993..69189
                     /locus_tag="ACF3UF_000286"
     CDS             67993..69189
                     /locus_tag="ACF3UF_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFD3670446.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(69290..70666)
                     /locus_tag="ACF3UF_000287"
     CDS             complement(69290..70666)
                     /locus_tag="ACF3UF_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3670447.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(70703..71569)
                     /locus_tag="ACF3UF_000288"
     CDS             complement(70703..71569)
                     /locus_tag="ACF3UF_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFD3670448.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(71658..72683)
                     /locus_tag="ACF3UF_000289"
     CDS             complement(71658..72683)
                     /locus_tag="ACF3UF_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3670449.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(72701..73375)
                     /locus_tag="ACF3UF_000290"
     CDS             complement(72701..73375)
                     /locus_tag="ACF3UF_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3670450.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(73559..74452)
                     /locus_tag="ACF3UF_000291"
     CDS             complement(73559..74452)
                     /locus_tag="ACF3UF_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3670451.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(74526..76223)
                     /locus_tag="ACF3UF_000292"
     CDS             complement(74526..76223)
                     /locus_tag="ACF3UF_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3670452.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(76216..77529)
                     /locus_tag="ACF3UF_000293"
     CDS             complement(76216..77529)
                     /locus_tag="ACF3UF_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFD3670453.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(77529..81798)
                     /locus_tag="ACF3UF_000294"
                     /pseudo
     CDS             complement(77529..81798)
                     /locus_tag="ACF3UF_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333417.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
BASE COUNT        23423 a        17335 c        14087 g        27059 t
ORIGIN      
        1 tctcgtcctg tatcctcggg aaattttata tattgaaagt atcaaaggtt tgaaaaacca
       61 agttatggtc aaaacaacta cagaagataa attagtgaat acttctttaa aacaattgaa
      121 gacagagtta gaaaagtatg cttacttttt acttttaaaa tcttactgta tcaacttatc
      181 gcaattgcag aaaattgatt ctgctcatta tgtgttagaa tttttcaacg gtgactcctt
      241 actcgttggt cgaaagatct ttgaaaagac aaaggaacgt ttccatgact tccaaaaaac
      301 tgcttcgagt tgatgaataa gagctgagac gtaagcatag cagatttcag ggagtgggcc
      361 ttgaatcggc tccactccct gaagtcgttg atatgatttt acgcttcctc ttctgtagga
      421 gcatctgtta acgaccatgt gaatgttgaa acgtagttgt ctacagcata attggataca
      481 ggaacaaata attccactga ttgtctccct tgttccacat tctctcctaa tgaataaatc
      541 catgtgccaa tcccttcatt tgctcctgca gttactagat ctactgcctg atctgctggg
      601 atttcgattc cttcagcgcc agttccagaa acggtagatg gcattccact gctattagtt
      661 gcgctatttc gaatcacggc gtttttgaat ttcacctttg aaccagttag tttattcgta
      721 tcagatgttg taccaataaa ttctgttcgt ttgactgata atttccaacc ggcataattt
      781 ccgcttttat ccgttacttg tacgaaattc tgtacttgtg tttgtgctcc agtactgtcc
      841 gttccgcttt gtaatgcagc atatactgtt tttgctgtac ctaacttgat tgttccaaaa
      901 tcaagatctg gagcttggtc aatcgtcagt aatccggatg ttccctgatt tggttcgtca
      961 ggtgtaaaag gagtatcagg atcatttgga tcaacaggag gaactggaac aacgtcttca
     1021 ggatttgcag catctggttt ggtcacagaa atcgttcctt ctgtagtggc tgagctctta
     1081 ttctcagcaa aaacactttg tgtacataat aatagacttc cagctagaac ggtacttaat
     1141 gcaattgttt ttttcatttc tttttccttc tttcttttaa aataaataat ccagcaaata
     1201 agccaataag aatgactcca acaagtatca gccatcgcca gtcaaatgtt tctggctgat
     1261 tttttaaatc aatatccttt tcattcaatt ggtccgctgc atcatcagtt atttcaaaat
     1321 cggtatggag attccagcgt ttttctttcc aagcaccctt cacaaccgct tgataatgtc
     1381 ccggagctaa tttttttcct tctaatggga caagtaaatc aaaatttgta ttgggtgcta
     1441 catctatttt ttcttttttt attgaaaggt aaggctcttt tgtttctttt ttgtagattt
     1501 caaccgatgt agtcaagccg aacatataag aagcatttgg attttgaaga ttcgccttaa
     1561 tcacatttct tccatcgctt tgatccgcat aagctttttt taatttcaaa tctggggaag
     1621 actctttttc gctatttcaa atcaagattg ctttcacttg agaaaactga ttgacgacac
     1681 caactgtact tttgttagaa acgttctctt ttttttcttg aaacgtgatc cctcctgcga
     1741 ccacaccagc cagctctttt tctggcgctt tcagtgaaag tgtctcagtg accgcacttt
     1801 gaggaggaac agttatttct cccactgttt ttgctaagtt tttcatatca taacttaatg
     1861 tttcatcaaa tttacttttt gattctccat attcgatcac accgtttgaa ttcgtcgtag
     1921 cggagtggat caatgtctca actgttactg atttatctgt tcggttaaag accgtgtagg
     1981 ggatttcctg tgttttccca ggctccatcc ttacatttat atatgttttg ttcttatcaa
     2041 tctgattagc cggtaattca aaatctaccg caaaattgaa ttcggaggca tggacaggtg
     2101 tctgccaaag gatgaatcca aggagaagga tcataagtaa agagcagttg tttcgatgac
     2161 ttttattcca tattcgattc atcaatcatc ctccttgatc tttattctgt cggcgcatct
     2221 gctaatgtcc atgttatctc tgctgagtaa ttaccagcta tctgattttc tttggttaag
     2281 acaagtttaa acgcccgacc gttatttaaa tattctgaat aatctgcttg cacattcgtt
     2341 gaattttgtc ctctgacaat ttccagttct tcttcattca ctaattgata ctcctctcct
     2401 ttcttgaaat ataggacatc ctgcatagaa aatcctgcat catttgtgaa aggctgagat
     2461 aattttatcg ttaagatcca cggatttttc gtttctcgct gatcataaat ccataatttt
     2521 tcctgtatat ccatttggcc aaatgcttct tgtgtcaaac cagttgcttt gatctgacca
     2581 aaatcgagtt tggaaggggc aagaaatgag agaccacctt ctactacgat cttcgtagca
     2641 ggtgcaaaag gcggggcatc atgataaaca actggcgtat cacttggatt gtgattccca
     2701 atttcatcgt tggtacttgg cttgttctgc acacccttag cagtagcttc tcctgcttgg
     2761 tcgtttaata caatttctaa tacatctcct gcaaaaagtt gattttctgg gatagaaaga
     2821 acaaattccc ctgtatcatc aatagttgtt tctgacaaaa cagcttgatt ttttttcaat
     2881 gaaaccaagg ctcctgcttc acctgtacct gtgatcgtgc gagaagctgc attgatcaat
     2941 gtggtactta aattagcagg ttcaggagga atcacatcga ctgtcgtttt ggcagagtcc
     3001 agttctgtca cttcttggcc acctcttact tttttagcag caacaacttg cacttgatcc
     3061 tccgttttta atctctcatc attgggtact tgaacttcga acaagccgcc ttgttcgcct
     3121 tctccccatg ggttatatcc tgccccttca ttttcatctg tttgtccttg cgtgagagca
     3181 gtaatttcta cagatgattt cgtcgtatct gcgtaagtaa tacgtaaagt cacttctact
     3241 tcgcctgtcc aagcatctct tggctttgcc tcgacacctt cgggaacaac gacatgccca
     3301 tagatttttt tatctgcatt cgttggcact cttaaggatt caatcatcgg gagctgatta
     3361 ttggcactga ttcgattata atttttcatt ccggcacctg tctgagcaaa ttcatttgtt
     3421 aaacctgcac tagggcttga tacgaaattg cctaagtcgg tcccattgat cgataagtct
     3481 gtcatatcag aaaaataatc cgggtctttt tcaaagttat cgaatgttgc gcctgttttt
     3541 cgccataaag cgatttctga atgggcgatc tttaaagaag aatctccatt tccttggaat
     3601 acccagccgc ctatgccatt ggtctcgctt ccaatccgtt tgttttggaa atcaaaatag
     3661 gtaggagatt ctaagtccac attcaacaca tccccactga tgatgccggt cttatcttcc
     3721 cctgttttcc cgaccatgac taaataagtt ttttcacctg ccgtaaaatt taaatcaata
     3781 tctccagttg tatctacagt tgctccggaa tctgcgcgta tatcgatatt tgatttttct
     3841 ccagtgactg taaaatcagc tgaacctgga ctttctagaa aaccagaagc gtcataaaat
     3901 tggatcgctt gatttccttg attgagtctg ttcacgtaag atttgccatc acctgtattt
     3961 cttaccctca atgagcctcc attggttact gtcagctttt gcgtaccatt ctcaaaacga
     4021 actgcgctgg aacgcccact ctgcttatcg atgtcgataa ctgatccggc tccttctacg
     4081 atcaaagaaa ggccttttcc tacaaaacgc atcccattgt tcccgggttg atcgtcatct
     4141 ccagccattt tgaccgagat ttgtccacca cttgatacat ggatttgact agaatctcct
     4201 tgcaagcgaa atccgcccgt agttgctgta ttgatggtga ttttcccacc attcgataca
     4261 gtgactttcg atcctgaacc tctcatttgg atgattccgc gattgttgtc attggtaata
     4321 ttgatctttg tatttaccga aaattcgctt cccgaaccac tgacttcaaa catgacatta
     4381 ccaggtagcg tatcgactgc ctctccttca tcgctaacgc catctgcccg atcataatca
     4441 agagagacct ttgaaccgct taagatatgg attcctggcg ctgtttttcc actaccagtc
     4501 tcatctcctg aatctagaaa accgtagaat ttccctagat acggtccata aagttgacta
     4561 ccattgatca cattcaattg atagcttcta caaaaatagg ctttacccgg agcggcattc
     4621 agtccttcct tcactggttg gacatccaac acaccggaaa caccatctaa tgtgacagtt
     4681 gcacgaggag cgtaaatcag tcctaatttg gacccatcat acaaatcaag tgtcccggta
     4741 aattttattt ctcccgtaaa atgatatctg cttccccaaa aatcggtcat ataagcaatg
     4801 ataatggcat ttccatcgat atttggtgtc aatccacctg gatgtgcagc tgttccttta
     4861 aaattctgga actcgatcga ctgaggtatc tcattgatat aaatatggtg tgtgccgaaa
     4921 ttgtgagcga atccaccaaa atcaataacg atatctcgtt tgatctctaa ttccctgtct
     4981 aaagtcaaag gctgaatcag tcggatctta gttactgatt cgtctgcgag aagctgcgcc
     5041 agttcttctg ttgtggcagc ttcgctgtac ccatccgctg aaacagctct tgccagtgcc
     5101 gcttcactgc tatcagacgt ttgttcagct acttctgagg tctcacttgt cttattttct
     5161 tcttgccttt tattagtaga agcctcactt tgagattctg tagtttcaga agtaatcgat
     5221 tcttctgaaa aagtagtctt gtcaaaactt tgattctctg attgcgttga ttcgtttgtt
     5281 ttctctacat cggcaaaaac ggatgtcacc atcaagagag ggaagacaaa caaaatcgac
     5341 gcaatcagct tttttacaca ttgattcatt ctccaccatc ctctctgacg ttttgacaat
     5401 tttattttat cgttttaatc tatttccaat tgtactttca tatttaaaat atgtattttt
     5461 atggaaaaat ttttctatta ggtgtaaatt tcttttttgt acaaaaaaaa ggctgtgaca
     5521 aaagtcttgt cacagtccct tatcccgaac aagcggtgtt ctcccgccaa ctcctcggtc
     5581 acaacctcca ttttaacaat aaacctgtaa atgtgagggc aatactttga ttgtcacagg
     5641 taatttatcc ccttcatctc catcaacatt cgtcgtcaat tcttcctcat cagctaatga
     5701 cacaactaat tgctcacaag taaggtaggc tagatttttc gtagattcat ctactccttt
     5761 taataggtct ggcaatgttt taagcgtatc gatcaaagaa gaatctttta aataaaccaa
     5821 atggagctta ccatcatcca cttttgcatt tggaagtaat gtttcaaaac cgccgactga
     5881 gttagttagt cctatcagca aggtactgct ctcaatttct tccttctttc catcaacttc
     5941 tacgtgaaac gagtaggatt gtgtggaagc taactgtttg attcctgaca tgaaataagc
     6001 tagttttcca aatttcgtct tcttctccgc atctacatca ttgattgatt cagggataga
     6061 gccaattgcg acgacattca taaaatagtc gtcatttatt tttccaatat ccaatggctt
     6121 gactgattca atcgaaaaat gattgatcgc ttcctcaggt tctagcggta tccctaatgc
     6181 tcgagccaag tcattcaccg tacccaatgg gaaaaatccg aaatttggcc gatgttcttg
     6241 ttcagcgatt ccactgattc cttcgttgac tgttccatct ccgcccatga caaacacact
     6301 atgataccct tccgtagccg cttcgcgagt aaagtttttt gcatcccctg ctttttttgt
     6361 atgcaagacg accacttcat caaacaccga ttccaatttt gctatcgcta attgctcaaa
     6421 ttcctttgct tgttcaccgc ctgaactggg gtttaccact aataaaactt ttttcatcac
     6481 tttctttccc ttctgattga tttctttaat ataacgatag cataaagaaa aaaattaggc
     6541 tgtgatgaag tactgttcat gaaacattca tttatttttt gacaagataa aacatccata
     6601 ctatgaaact gaggaaaatt aaaacaatga tataggaaat aaaagaaaat gataggcatt
     6661 gtatacctaa taaagtaaaa atcttaggtg gcagataaaa acacaaaaat agcaagagaa
     6721 tgtaatagcg tttcttccac tttttgttat cagaccttat agcgatcaga ggaataccaa
     6781 atgcataact gaaaaactct tgatgtactg ttaatatgtc acggccttga ataataaatg
     6841 cgacaatccc cgctataatt agtgtgccta acaccaaaac ggaaaattga tgaatatatt
     6901 ttatatacaa atgatccatt gtacttcctg cctttttatt tgtgagaaaa acaaatccgt
     6961 atacgtgaat aacttctaga aataaaagaa atttgcaaaa ccactccatt tatctacttc
     7021 tacgtgcatt ttttgatatt gttttcttta tttaagatta tacagaaaaa tatctagggt
     7081 cgctggattc taagtaaaaa aaatttttaa aataaaaaga actaaatcaa gtagtaatta
     7141 aactactgtt gatttagttc taataaaaag atttagatga acagttttat tgatttaaat
     7201 agttcatatt ttttatttat accgcttatt tactacttgc tgtactagaa tctgaagtga
     7261 atgtactcaa aacattttca aagtctttgt ctttgatttt tacattagcg tctttcaata
     7321 cttcgccaat tactttattc tggaaggtac tgtcacttaa ttttgtgtct gttgcaattt
     7381 ctttcaattc ttttttgtat ttatccatgt cgttgccttt gttttggttt ttcaccattt
     7441 taaccacata atattccgta gtataagttg aagcattggt agaagtgatc acatcagaaa
     7501 cttgaccatc tttcaactta aaggctgctt ctttgacttc tgccggaacc gttgtagtag
     7561 tggaatcaaa tttcactttt ccgccatctt cttttgtcgt agtatcagtt gacttgtctt
     7621 tggctaattt agagaaatcg tctcccttat cagcagcttt cttcacatct tttgcatcat
     7681 cttcacttgc tacttggata atttgagctt ccacttctgg atggaaagat tcccaagccg
     7741 tttttaaatc ttcatcggtc aatttgatat gtttctttag accttcttga aaggctagac
     7801 tttgtttgat actgtctttg aatgtttgtt ctgtgtaacc tgcagatttc aattgtgaat
     7861 caaatgaatc acccaattgt ttctttgttt gatcatattg agaatcgatt tctttggttg
     7921 atacgtcatc tccatattta tcttcaaata cttgataaac gatcaactgt tgcacagcgg
     7981 aatctgctcc ttgcattttt ttcaagctat ccattacttc ttgttcgctg attgtaccgc
     8041 ctttataact aacggctgtt ttttcaccgg cattcgtaca gcctgacaat aagccagtgc
     8101 ctagtacgat ggcaagtgct aaaaatcttt ttttcattta tcaattctcc tacttttcgt
     8161 tttttgcgaa ttgctaaaaa caaaggtgtt caagatgaaa atcatcaaga acacctttac
     8221 taatctgctc gatacgtcct gaatagatat aaggctacac aatccagaaa gttcgctcag
     8281 cagaataaat gtcaagtagc acatcacacc ttaatatact acttcttttg ttaccgtttt
     8341 tcaagtctat cttgcgttcc gtatttaacg taactaattc ttagaacaaa tgttatcgat
     8401 tttgtttttc ttcttccgct gctgggatat tcaaatcaga cacttttatg ttcgattttc
     8461 cagacatttt tttgttgttt ttattatgat atatttttat acaactaaaa atgaatatat
     8521 taaaactacc aaaaataact tttaacgctg tttcattata tgttttttct attttatata
     8581 aacttttgga tacttaatac caaccggttg gattgtacca acatgagaat gtgtcagttc
     8641 tatttcctgt cgcacttgca taggcccata ctccttttgt tgcatttgct gatcgaatag
     8701 agtttccaac tttcgctttt gcaccgtgac gattatagac acgactatag tggttagaat
     8761 gacctgtttt tctcgtacaa gttgtatcac tataataaac ccatcttcca gagctatgat
     8821 taattgctgt tctagaaatt tcccggtcta ctggtaaatt tgacttaata atattacctt
     8881 tagcatcaaa atgaatctct cctggcttta aagatttgta atagatttca ccgtgaactg
     8941 aatttgcttc cacttcagat gacatagcgt ttcctccaac aaaacctatc cctagtgcac
     9001 aaataataac tgcttttttc ataaaacgac atcctttcct ttttgatttt taaagcatga
     9061 tcttcttgtt tcctattttg gtcagatatg gatcatgcgt gactacgata actaacgtac
     9121 cttgggaagc ttgttgcgat aagatttcaa ctactttatc cttatttctt ttatccaatg
     9181 acccagtcgg ttcatcggct aaaatgattt tgctattctt caataagact ctcgcacagg
     9241 cgattctttg cttctcacca ccagataatg tgtagatagg cgtacttagc ttcttgttta
     9301 tatttacttt tttcaatgcc tcatactttg ctgttcgctt atctgaaaca tttaaattcg
     9361 aaaacttcaa tccaatatct aaattaaaat cgattgtttc atattcaatc aacccaaaat
     9421 cttgaaaaag aaaagatatg gtatttcttt ttatcaagcg cttctctctc ccagttaatt
     9481 gtttcgtctc ttgatcgaac aaatagaatt gtcctgaact gaactgatca ttcaatccta
     9541 atatattcaa taacgtactt ttacctgctc cactttctcc aacaacagtc acaagatccc
     9601 cagcatccgc agtgaaacga tccaaatgaa gaatcgtttt gtttcgaatg atttttttcg
     9661 caccttttat cactatcaac ggctccaatt gttaacctcc attcatcagc aataactgac
     9721 ttttcttttc tgtagacaaa ataaaaacaa ctgaaagaat aaaatcaatg aagctaaaga
     9781 aaaaaatatt aaaaagatat ttaggctctc tttctataag aaaaaggaag attacacttg
     9841 tcgttcccca tttgatgagg ttcatcatga agaaatcttt atacgtttca aagagcgaat
     9901 aaccacttga acgaaagata gcgattttcc gacaattgta gacaaaatat atgcataaca
     9961 tgacatagct caacaagaag aaagaaaaga aagtgagtaa aaatatctgt atcaagtaat
    10021 gaaatgatct gcttaacact ttgacagcta tctcttcagt ctgagtatac ggaaatgata
    10081 actgcaagtt atcacgtaac tgactttctt caatcagctc aaataacctt tctttcgaca
    10141 aagagcctat cttgatcttt aacggtggat agatttctcc gctgagaata tttctttcca
    10201 aatacatact gtttttcaat gtcagtattt caacaaccgg ataatgttcg atccagggga
    10261 tagaaggaat aaatgtataa atgggttgat tgttttttat aaatagaaat ttcggttctt
    10321 tttcactgat ttcttgataa tattctgtta tttgcgccag gtcatttttt aaatctgtat
    10381 gtctatatcg ttcagggatc aatataacag ggtgcgtttc tttttcggtt atttggatca
    10441 accttccaga gacatcaatc aaaggaaatt tcttaagata attcagattt atttttatcc
    10501 ctctgccaaa ctgttcattt tcttcattca agtaatctga tacattgact aatatacttc
    10561 cgtttttatt caaagtttca tataattcct gatctgctgc tgatgcaaaa cgattggaat
    10621 aaataaaatc cacgtggttt ttcccgatgg ttactggata aaatacatga tagtcctcac
    10681 cagcgatttc ttttggtggt tcatgggaaa cagctaactg tgaagaagaa aaaacgatag
    10741 ttgctaattc gacattggca acggtcaaaa gaagagaaaa caacaatcca aatgtaaaaa
    10801 gaatgtattg gatatagttg aacgcttctc ttaacgaagc gattttttca actaataaaa
    10861 gagaaatcaa agagatacca tatattccgc tgaacaagaa aacgtacatc tggaacaaat
    10921 aaagaaattg ctccttataa tacataaaaa taaaaccacc aatgattcct gcaattatga
    10981 atgtaataat gattttcttt ttccccaata aacaccacaa tacttgatgt aatgaaaagt
    11041 cattattcaa caataaactg atttctttat tcatcaataa gaaaaaggat gataacaaaa
    11101 ggaataaaag aatcaatcca atagttaaat acactcgata attatatacg tctgtatttg
    11161 aaataaccga atacgaatag ctattttcaa agtcttcaaa aatattagtg gcataatcag
    11221 tgtgaaatgc ttgattgaat cgatcagtga atagtgaaat gacccgttca taggcttctt
    11281 tttctctcgt catcaagaaa aattcacctt caaaatcttt tattttgatc gattcttcaa
    11341 tggacgttac gcgaaaggag gtattagaat agggtacctt ctcgtgagaa gatttgacat
    11401 ccccttgata atacaatgtc atttcaagct ttggctgtat cttgaagttc caagatgtat
    11461 ctacttcatt ggattcattt actgtttttt tcatataaga aagctcagtt tctgatgaga
    11521 cattttcaaa taccatgatt agctgctcat attcttcttg cccaataaaa tgttgtggca
    11581 atcgaatcgg agtataagta tctgtttgat ggaaaaattc atttgtccga tagagtacct
    11641 gtttatttat actaaccaag gcaaaaccac tcatgatacc ggtcactatg attgtgagta
    11701 aaactgtgaa cttttttttg attatcacca ctctccctta cttaaatgat tctttgataa
    11761 aatcataccg tttttcatca aaaaaacgta tctatcaagt gtataggtca tgtagaataa
    11821 atctatatac tgtagaatcg aaaggagaag aagatgaaca ccggagaaaa aatacgaact
    11881 taccgcagaa attgtaagct tacgcaaaaa gaattaggcg aaaaaattgg tgtttccgat
    11941 aaaacgattt ctagttggga aaattctcgt acaatgccag actttgaaat gctgtcactt
    12001 ttacatcata ctttaggtct gccgattgat tttccttcta ttgaatcagc taccgaatca
    12061 atagaaccaa cattgccaga tgaacctctt gttaacaaga aatcttattc atcaaaacaa
    12121 cccttctcac tcaaaaagac actatctttc tttctgctcg tcttttgttt ggtctatctt
    12181 tttcttatca attatcaata caaaaatgaa acgatcgatc gattcaatcc ttttttgaaa
    12241 ccacaaatcg gctataccac actccctgta ggatacgtgg acaattccat cgaacgttgg
    12301 gtatgtaatg atatctttgg ccatggtaca tggctgtctt ttcacgctgg agaggtagaa
    12361 aaagagaaaa accatgctgt aatcaaacac aaaggaaaac acgtcatgaa cgttcgcctg
    12421 ctcacttggg aagccattcc ctcagattac caagaaatcc tcagccaaga ctatgacgac
    12481 gccttaaaaa gaagccctca ggagccagat aggcattaag taggagatga acgtagagat
    12541 agaaaaaatc aatgcacatg atcttatcca aaaaacaggg gtacaaatta attgaaaaag
    12601 ccttgagatg aaagttccta aataaaaaag ttcagaatga taggtatttc tggcttatag
    12661 tataatattt acgccacagc ctcccaatga ttctttttgg aatcataatc aaggatggac
    12721 attcacaaaa atattttgct cattcgatcc gaatagatta acgaccaatc tagtaagtaa
    12781 tatagattgg tacgtagtca agctgcacat aatttagatc aattttagtt cttttttata
    12841 tttctatgat ctgctcattt acttttatat gatggcttac agtaacataa ataaatatga
    12901 taatcgctgg tagtttatcc aagagtactc aataaaatac aaaatggatt gttcaagcgc
    12961 ctatcataat gataaaatga aacaaataaa cgatacaagg aggaagagac tttgagtaat
    13021 ggcagaacaa ttttttcatt gtaaaaattg ttcagttgtt aatctatggg atttcggtag
    13081 catgggcatt tttttataga ggaatcacac caacctggcc gttttatctc ttgttagtgg
    13141 gaatattagt aggaaatttt gcccctcttc actatcgtac gaactttttt ccaactgatt
    13201 ctggcctttt tcttaaaaca aagacgcgaa aattagaaaa cattattgaa atgacaatta
    13261 cctgtataat cattttctta gttatattcc taaacgtctt ctaataagaa tctcttaaaa
    13321 ttagcttgtt acagttagtt acctagttta tataacacag ttatcttatc ttccttatca
    13381 acatcttttg ccaactcttt gtcttaaatt cgaaacatat aagcagagct acgaacacca
    13441 agactgtttc ggctctgttt tttgcatcaa attcactctt atatagctga taatctcggc
    13501 tctttaaaag aaattatttt cgcttcattt tattataaaa aggctaggaa ccttgatgtt
    13561 atcaggttcc tagcctttat ttaagtatta ccccacagac ccttccatat agatttttga
    13621 attacacact agtttaaact aaaacaaaca aggaaaaact taccatttaa tcataaaatt
    13681 agctcatatg aatatattag aatgtaaaat agactggtca aaatctggtc aaaaaagagg
    13741 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
    13801 tattcccttg ttcgatgtag actcaaatca atctctttac ttgctaacat cctttatttt
    13861 accttgacct gttgataata gacagttaaa tcttgattta aagtggggca attaatcaag
    13921 aaaacagggt tctaagcctc atttgttagc ttgttctctt agtaatattc ctcgtgaaga
    13981 atcgggacga ttgtttggtc aataaacaat atctcacttg catcgaaaga atatttcttg
    14041 aacaactgca tatcaacttc ttcaatacct acattccagt taatgtctga acctgaggta
    14101 aaatcttgta ctggtatgaa catgaactta tctttggata ggtgaataga tgtcactgct
    14161 tgaagtaata aaaatctgta aaaacgtgtt cgtaaatact tcagataatt aattgcttcg
    14221 gtttcggtat cagcagaaaa tagcactagg tatgaatctg taactacttc attaggttta
    14281 ataactctgt tagtagaaat caccttaaac ataccatttt tgttcggttc acctgcatgt
    14341 tcgctagtca gtgagctact aatgacttta tactttccaa ccatatcctg tcctttagtg
    14401 atatcttcca gtggaacaaa gcctacccca ccactagaga ttacttttat tgaatttctg
    14461 gaatcctgca cttcttcccc tcgaattttc gttggaagcc caaatgggtt acgtgatata
    14521 acaaagtcac caacactagc gtgttcccca attttgtgaa ttgcagaaat ggcttcatta
    14581 tatcgcacaa acactggaaa ctcgttcatt tttcgctctt gtgtatttga tacaccatca
    14641 tgttgattag tatactgtgt caatccatta tatttcttat cccacaagaa atagctaaca
    14701 ccgccaccaa tactggtgtt tgggaatatt tctttcccat ttactatatc caccatcacc
    14761 ttcaagctag agctgttaag cataaagtca cggtacttat ctaacccttt accacctgca
    14821 aaccacttcg aaggagtaat catcgaaaca tagcgttctg ataacttaac agaggtttct
    14881 acaaatagat tatatagcgg tgtagcacta gctcctgaac ctccatcttt ctcctgataa
    14941 ggtgggttac caattatcac atcaaatttc acgtttttat aaactccttt caaattcgtt
    15001 aaaccgtcat tgattgaacg tttcatactc gtaactaatt cacttgagta ttcaacattt
    15061 accttccatg cgttataacc aatcaaagtc ctcttcgtta tcgtcttagc cattggagtt
    15121 ttagaaatga caaaaatttg ctctgataat actttttccc atattgcctc tgaatctacc
    15181 cttccagcat taatatcgct ttgtttaagg agctgaacat agtacatact cgttgctgca
    15241 tataaaggat atagccctgt ttttgagttt atctcaagaa tctttctatt ttccttaaaa
    15301 atatcatctg tacagtcagt tttcctccat cgcacgattg gttgaccgtt ctccgtagaa
    15361 ttttggtatt cttcatcaaa gaaggaaagt ccaccgatag tgttaccaag gtgcatatta
    15421 acaactcgcc atggagtcaa tacggtttcc ttgtctggat ttttaaaagt gctaaataat
    15481 tcacctattt tcctagtacg ttcaataaca tctaactcat cataagactt tgcacgtcta
    15541 cggattatgc gtcctgcctc cacaaaaacg tctgcatcat agtactcaat aaactctctg
    15601 aatcgccctt tacttaaccc ctctggcatg aactcattcc atgaagcctc atcaaccaaa
    15661 ttaagaaaca tctcaatagt aacgtcatct ttaatatcaa tgtccatccc ataaatcatc
    15721 ataggtatgc gaatagaaac gcccctcaaa atggaaatca ttttatttcg ctgctctcga
    15781 agcctctttg ccctatctat tgcttcctgt tcctctttgg tacgttgacg ttttggtttc
    15841 ttttctgccc tcgaagcttt ttcatactcc tcttcactca taccgttatc tgaaacaatg
    15901 aagtctttca ctttggttgg tttacttgag ccaacaattt ttttaaggtc ttcaaatttg
    15961 gtaagatcag cttggtctaa atttaatagg ttgtcattgt aaagagagct gtcttcaaag
    16021 ccagtccgta cagctttttc tgcataagcc ttcttcagtg ccgtaagcat tcggtcaacg
    16081 ctaaattctt tcatcacatt cccctgttta ccaaggatag gtaagaaatt tagcatgcgc
    16141 tctagttttt tcttttgctc tgaactatta acctttccct tcttgctagt tagtccgaca
    16201 cttccactca taatttttaa agcacggtca ggtgcaaaat caaagatgta gcagtttttc
    16261 ttaattccaa gctctgcatg gttaaaaggt gtctgtgcac ggaacgctgc ctgcagataa
    16321 gatgtaggac tttctgtgtt tgaaaggaaa aatacccctg tccactctgg aacattaact
    16381 cctgttgtaa gcttgcgaac tgttaaggtt atcgtcttag acttagctgg attaccaata
    16441 gctttacgca ccaattctaa atctgaatca ctagcatgct cactgtcacc tgtcttgact
    16501 acgtttgcaa tattgtaatc tttgaatata gggtgcgttt cgagcactct ttcaaaagca
    16561 tttgcctctt taacccccgg catcagccat aaagtatgcc gtaagttttc tctaaactct
    16621 ggttttgaga aaggaaaatt agtcttttca tcgtttgtag taatataatc aagaaacttg
    16681 cgtacgtcac cttcatgaag caactttgtt tcatcatctt ccttaaccct aaagaattct
    16741 cggaagttaa atgccttatt ttcatcgaaa taatcaaatt tatttggtat ttcaaaggtg
    16801 aacatagata ctttcggtaa accttcgtat gggttaggtt cattgggatg ctctactgac
    16861 catttctcct tagcttcttg ctccatagta taatcccaag tgaaaatatt atcctcatca
    16921 tacttatcga aaaggttaaa tggtgtaccc gaaagctcta agaccttggt atgctctttc
    16981 cgcaacttag cctttacgtt attagctaat tccgtttcgt ttccttcgtg agcttcatca
    17041 ataataataa aatcccagtc aatcgctaag aattcatagt ttttatcccc tgcttttcca
    17101 cctgcccact cagaaccgcg taagtcctga atacttgcaa aatagatgaa aggtttttcg
    17161 gtatcaacaa ggttttgaat cttttctcca tcttgttttg aaccatagat gtacgaacca
    17221 tctgtgaaga tttttttgaa atccgtaaac caaccatcac ttacaacagg tcgatgagtc
    17281 atgataagaa cttttttgta ttggctctct ttaatcactt gaagagaaga aagcgtctta
    17341 ccaaaacgca tcttggcatt ccaaagcatc tcatctttcg ttttgaatac agtcttagtc
    17401 tgctcaatag catctttttg ttctggtcta aaattaattt tgaactcgtc aaagtcatct
    17461 ttttctgagt caagactacc tttaccatct ttaaccgctt ggattgcttt cttggcaacg
    17521 tcaactgtta cactgaacca ctcattaggc ttccctgtgt catcttcgcc aatcgtttga
    17581 ggattatagc ccgaacgctt taatacttca tgcacgtcat ggtcacggaa aaattggttc
    17641 ttcttattaa cagccaattg cgcccaatga aggacaaaag gtacccccgc tgttgtcatg
    17701 tactgcttta ttcttctact tgcatactct cttaaatact cgctattagg agtaaagtct
    17761 gcctcataat tctctggtac tgatgcatcc ccaatctttt ccagtccttg gtacattttc
    17821 catgtgccgt cagcatcctt ggcactctgg atgtaaataa gtttacggtc aaaggtgtta
    17881 taggtgataa caaacatctc atccgtaatt tcttcctttg ggtttaacga tttatcccca
    17941 gacagattgc gtgcaaagac tcttagcaag gtatcaagag taactaaaga ttcgaccgcc
    18001 tctgaaacag gtataattcc attttcatgt gctgcaacat ttccatattt tctcaactta
    18061 tgaaataagt cagctatcgt aggagtaata ttatttctga ccctaagctc gcgaagtaca
    18121 tcaacatact tcatactttg ctggtcaata cccacatttg aagcaatctt ccgtgctgct
    18181 acctccgaat aacgtctagt tccaatagca acttcattag gtatttgatt aacggttaca
    18241 cggtacgtgt taattgcatc tactaaatta ggaatcccaa ggaagtgttc tagcttagaa
    18301 ccatatttag gtaagtaatc gaagtattta gctttagatt tcaacgctgt cgtcatcaat
    18361 ttcctccatc tcttccttat aaacctcagt tatcggcatc gctacataac gtaatattgg
    18421 atcatttgaa acttcttcat cgacctcgtc atcaaatgaa aacaaatcga gctgttcaaa
    18481 tacaggcaga gctgagtatg cctctccaaa ctctcgtgtt acccctgaat aaatatcctc
    18541 caaagaatat tcagttcgat ttacagtgat ttttttctgt ccttttctta gcgtcttagg
    18601 tgtccactca ctaaaaataa tcggattatc atctggtgtt cgttttgtaa gaaaatctcc
    18661 ctgtttgata ttcctagaaa tcaaagtctt tgcactgtct tggactttcc ttttcattgc
    18721 ggtaccatgt tttttcgatt gttctctgta caaatcgttg aatacttgaa acatgttcat
    18781 tacacaggtc tgagcattgt cttcgagtaa ctccacgcca tatagagttg aaagcgccag
    18841 taaggagtaa ttttcatact gttctaggga ctcattatat tcacgagcaa ccattgccat
    18901 ttttctagtc aaaacctcaa ctaagaaagc accttctcca gctgaaggct ctaagaaagt
    18961 cgtctgcagc tcctcgcaag cctcttttat gcctggcaaa tccaacatat ctttgacagt
    19021 tctttgcggt gtaaatacct caccgtgctt ctggacacgt tttttacttt tgattagtcg
    19081 tccttgttcc tcttcaacca tcaccatatc ttcaaccact aaaaatcacc catcttccca
    19141 acacaaataa ccgaaacgga tgctacgaat cggttatcac tttcatatat gggcttttgg
    19201 gcagactgct ggctagtact gtgattgcgt gtcatcatgc ccttttcctc cttacaagtc
    19261 aagattttta cttgaaaaaa ctcgacaatt tctaattatg cttatgttca attttaacac
    19321 atttttgttt tttcctctat ctcaaaataa agaacaaaat atagcttaac tggagaatta
    19381 tagagtttgc ctcttgcaac acaggggagt tagcgaagat gttcgtctgt cctattttat
    19441 ttttatgaac atgaaaaaag accaccaaac taggcagtct ttgacttatt attatttact
    19501 tttagctatt cccattaaat tttaccactc gtcccttttt cgccctcttt agatttagcc
    19561 gagggtcgtg tggtaaaagc tcattattgt cttaacgtgg tcaaaaacct ctttcctacg
    19621 tttatttgat aacccatact gacgaaacac ctctttcatt atcgcaatca tttgctcatt
    19681 agataacttt tcatcatacc catcaatgaa gttctctaat gactgactat ctaaagcttt
    19741 ctttatttca aagaacaagt cataaacagg tttatcttgc ttcttcagcc agtgaacata
    19801 gccctccctg tgctcttttt cccgttcacc tgttactcct tgctgtttag gtaatcacag
    19861 aatgttgacc gactgacttc tatacctgta tcttcttata ttctcgataa agacttctta
    19921 atggtgagtc cttcttgata atacttcagc ccagcctgta aaacttcgtc tggaaacctc
    19981 tttcgatgtt ctgtcttgtt cgctgaaaaa ctcttgtact catcatcaaa gctgagtgta
    20041 aataccacaa caagatgttc gtacgatagt ctgaccagaa aactgacttc cttgtcgttt
    20101 gtacccaaat tttcatatga agtagataaa agaactgtat acctggaaaa gacgtcttct
    20161 tttacgaagt caatgcacaa tagacgtaga ataggctatc ttcttcgaca gttagtgaac
    20221 ctatatcgtc tgctaatagg atatccgact ttaaatctaa atatttttcc tctgattttt
    20281 taatttccct cttgaaataa tctattgtaa tttgtttatc tgaattgttt gcaattaacc
    20341 cctgcagaac ttctctagct tgttcaacat cccgtattac catggaaatc actaggtatc
    20401 aaactgagtc atacgaagac aaaaacataa aaattgacct gttaaagggt cactgaataa
    20461 catataaaat caataaaacg gagtcagaca cggagtcaaa aaacgctgag agtaaaaaat
    20521 atacagtccc ataggtaaag tgccacagga ctgtatattt ttttatttca gattacctga
    20581 aatgattcca tttacttttt atctcatttt tccctactag ttagtatcaa atactctcct
    20641 attttctcaa taaactattt tgggttacat ggtatctgaa acagctaaaa ccttgtcatt
    20701 acagcaaaaa atcactttat ctccgtttca tttcagatac atttcactta agcggattcc
    20761 caaaaaataa aagaaaaaga aacccctagt tagcctatgc tttctaatga ttcctctcga
    20821 aacacggtca aaaaacaacg gggtagggta gttaataaaa agatagaaaa accattattc
    20881 aatgactttc tcaaatattt cgttgtaatc agttaccttt ccgttcttaa ataccacaga
    20941 ataatctttt tttccatttt caagtaacct aagtggaata tctttaccga cttgctctga
    21001 caccgcatta ctgactcctg ttagattagc taataaatct gataaagatt gagcatcagt
    21061 cggaatctct gtatcagtat ttatcgttat tcccttatct tcatttacaa gtttccaagt
    21121 aggtggtata gccgcgtatg tttttatgaa cgtatcaatt tttttatcta cagtttgtct
    21181 tgatattgta tcgtttttct tttctacctt accaattgga ctctcatctt tcgtagtcct
    21241 ataaagagtg gctgttgata agtgttcatc caaatttacc aacacagtta atttatcttt
    21301 ttcaccgtca ataggcatga acgttatatt gcttattccc gtggtttcct ttaattctgg
    21361 aatcgcttta actaattcat cttttgatat catgattgaa cgaaatgtag ttgaatcaaa
    21421 ttttttatgt cttagagtat acttaaaatc caccatttca ccattttttt gtagttctat
    21481 tactctgtct ttagttattt taaaattata gtctacagga attttctcag cagttcctga
    21541 ccaatatcca tagaaatctt tatctttatt tctacaacct gataattgaa taaccagtat
    21601 agttcctata accaaaaata tacctgtttt taaataattc tttttcatca taaagctcct
    21661 cttttaaagc atttaatcaa caatgtaaga acccaatttt taaagctctt taaaaacaat
    21721 ttccatcaat tattataaca ttatttttct catctatatt agtattttat ttacagggaa
    21781 tcaaaaaaac tccttagtaa gcttacacct ttaggagttc ctgtttggac ggtatacata
    21841 atacatttaa atcaatttaa cattaacacc tcagtatatg gtatctctac atatacacgg
    21901 tctttctttg gatagtactc gacatttata ttgatagcac ttccattgtc taacgtagct
    21961 ttagcccggt atgtgttatc tccattttca tgagtaatcg tcacatcatc acatgaccta
    22021 tttaagttgt actgttcttg taaaatctgt gtcaccaatg gtttagatga cttctctaat
    22081 ccagatgtac ctgtcatttt tgaaaaaatg atacctataa tagccaagac aacgatacct
    22141 ataatgacaa acttcttgtt catatttact ttattcaact ttttatctcc tatctccaaa
    22201 ataatttgct cttatccctc ttatcagtac attgacatcc ctaaaagtac accaaagatt
    22261 gctccagcta cccctgctat catcaaaatc gtacccattt tctcatcttt ttctcgatat
    22321 aagtagccca taataacagc aacagcacca aatacaacag gaataaatgc taacgatact
    22381 accatagaaa tccaaccaat aatcaaatac agcttccctg tctcttgtcc atgtacgatt
    22441 tgttccttca tttcactaaa tgtctgctca gtacttttct ttacttcgtc tgctccagtt
    22501 gtctcatctg tttcttgtaa tgctccgcaa aactggcaat acttactttc atctgttatt
    22561 tctttaccac attttctaca atacatgtct tctcctccta aaatcattca attgcttaat
    22621 agttaactgt ttactttatt aaacacatca gaaaacagct cgtttattgg tacacttaat
    22681 atctcagaaa gcattttcat ttgatagggt ttaggaatcg ttctccctgt ttgccacgaa
    22741 cttacacatt gctgtgtaac attcattttt tttgctaact ccgtttgaga aagtcctttt
    22801 tcttttctgt atcggctgag attacttact tttttcatga ttctcccctc ctgttttatt
    22861 atatacaaca atatgatgta tttcaactca taaaatataa aaacttcaaa taccattaca
    22921 aatacaacaa cttgttgtac tatactgaga tgggggtgta ttaatgaaac agaaacaata
    22981 tgcaaaggtc attagagaaa agcgaaaagc tctcgggtgg acacaaaaag aattagctga
    23041 aaaaatcttc tctacacaac aggcagtagc aagatgggaa aattctgtaa cagagcctaa
    23101 cctcgatagc ttaacagctc tttctagagc cctaggaacc cctgtaagcc attttctaga
    23161 caatgttgtc gtagattatg aggaagagtt tttggctctc tatcgttctc ttagcactga
    23221 agatgcagtt cgaacaattg actatatgaa gctattaaaa aggcaagaaa atgaacgcaa
    23281 tcagctattg aaagattgaa aaataaataa cccaccgaac tttaacggtg ggtgtattga
    23341 gatgaaataa gattaagagc tatggataac ctgtctagtt taatacaatt gggtcttttc
    23401 tcttccttac tctccgtcca tcatctcttg ttacacttgt aaattgataa agaggaacta
    23461 attcaacacc agatgctatc aattctttta ttacttcatc tatccctgct ccttttgcta
    23521 ggtagactaa aaaactactg cttgctttca cattgtatag tttcttaata tccttagaag
    23581 ctcgttcaag agtgaatcct tgtttaacaa agtagcctct gttttctttt aaagcatttt
    23641 ccacgctgtt attcccaaca ttacgtagac gttcacaaac agtgttaata agttctttct
    23701 ctgtcattag atatgtccct tgccacgata agtcctgtaa aacttcatgt gcctcatcta
    23761 aaatcaattg tttttccttg ctgagttctg accgaaaatt ttgaggaaat actcttttag
    23821 cctctttttc gttaaaacat atcttaaccc attcataaga aaaatattga tatgtaaaat
    23881 gaactttttt cagaagtgga aggatatctt cattcaattt ttgaatcaca gaagttgcat
    23941 taaaaacgtc taatcgatag acattgcttc tcttatgatt aaagtttcct aacgctttct
    24001 cttcctttaa cctatttagg tattcgagca tcttcaaagg aacatcttca tcatctaatt
    24061 tttttatcaa tcctataaat gtcataaatg atagtaactt attccattta tctatgtcat
    24121 aagttttacc atagtaagaa ctcatttttt tagctagttg ttctcctgat aaaatacaag
    24181 tcacactttc cttactatca tcaaaaaaat taacatcaga aagcaaggca tcatagacac
    24241 gtcgcatttc ctctagataa ttatttattg tcctgaaaag cttgtcttcc atagattcaa
    24301 gagtgtcaaa aagtactttt gattcctctt tcaattttcg aaaatgtgta ggatacaggt
    24361 ctagattctc taatagccaa ttaaatgttt ctacccgact atctttctct agaattaaca
    24421 tcacaacccc aataaaattt tcactgatac cacaattact ggaatgacaa taaaaaatgg
    24481 aatgcccagt tttactggta aaaatactag cagatggatt atggtcgtcg tgaaacagac
    24541 atcttaagtt tttacttgac ttaagtaatt tattcatatc aatggttaac aatctttcat
    24601 aaatctcatt aaaagacatg tcggaggaat caaacaggca gtctttaaac cactgtttca
    24661 tttcttcttt gtcgtcattt tttatcaact taacaaaatc agtttcattg actagttcat
    24721 actctctccc tgaatcactt tgacaatttt tagaacatgt catggtaaaa tcaatcggaa
    24781 gctcagtaat atctaacatg ttgtcttcat taattattat cactgcatct gacttatatc
    24841 ctccaaaaaa cattctattc gaagcattta cattgtcatc acacccgggt atgatttttt
    24901 tcaagtattc gtaaacagca atcattttac tatagtcagt aattgcttct tttaatagaa
    24961 agacaatctt gaatttttct agattttcag agtaccgaat acttttttgt atcgcaaacg
    25021 cagaattatg aactaaattg atagataaag ccttttctat gcttaagtat ctactatcat
    25081 ctttacttaa atctactacc ttccccttct catctttaac agtgttatcg acatccagaa
    25141 taattactct agtttctaaa aactcttcac ttttgttgcc tttattcttt gtcttacttg
    25201 gaataaatga ttgtgatgaa tttagtatct ctacaaactc atctcttgta acttctctgt
    25261 agttatctaa acatcttttt cgtattctct ttttttcatc ctctataact ggtttctcta
    25321 atagtctttc tttatctaca ttaattggaa tattaatcat tggtgtttcc atttgtgttt
    25381 cctccttata aaattctgtt aaagactaaa acatacagat aataaacaca aactctttat
    25441 tactatatgt tttagtctta tttgtttact caacctttat actgttccat gaaactatca
    25501 atatcagatt ttttgaatct aatgaccgta tcaattttta taacaggtaa cccgtattga
    25561 gaaacatatt ttctaatcgt tcctactgat acacctagat attcacttgc ctgctgatag
    25621 tccatatact ctagagtaac accagaaata atgtcttcta gcataggctt tagcactgta
    25681 attatctctt tcacttgttg ttcaacttgt atagaaacaa tgctatcaat gatttgtaga
    25741 gacatatttc cccctccttt cgtgattact tgaacaaatt ttctaagaat catcttcgta
    25801 ttatttgatc aaaataaaag tattttgttg ttattaaccg attaatcaaa taaaaaatga
    25861 ttatcagttc atcgacatac acataatacc tcgatacaaa aggggtgtca atatgttgtg
    25921 tgaatttatt tacaacaccc cctttttgag gtatactaat tttaggaggt gtggtcaata
    25981 tgataaagcg tccaccaata aattatttag aacgaaaaaa gatactcgga acaaaaataa
    26041 aagctataag aaagagtaaa aaattaacac aaccagcatt tggtcttatg attaacaatg
    26101 gtcaattgat tgacaaaaaa actatctacg aatgggaaaa gggaacctat ttaccaatac
    26161 cagagcgatt atcccgaatt gctgatttgg gaaatatgag tatagaggag ttagtttgtg
    26221 gcaatgtaga agaatatatt ttgggaatta ttctttatag agatagcatt gtactagatg
    26281 gtataacatt tccagataaa aacctgttcc agcatcttcg tcaacagttc ccaccagtac
    26341 actctaattt agatacatgg ctggatagat attccaaatt agaaccagag atgcaagaat
    26401 ttattgctaa caagacttgt aataaagtta aaaatgaaaa aattagtctt ttcaatatct
    26461 taaaaataga agaattattc atcaatgcta ttatagaaga atttgacaat aacattcttc
    26521 tgctcactag cagtatagag gaacaactag aagaaatgat agatgaaggg atacatagtc
    26581 aagtggaaga catgaattat cccgaagaag ctgtaaacga aattattgat aatataaaca
    26641 agctaaaaca aacgatttca tcaattggga aaaaatacac taagaaaaaa atgaagggag
    26701 gtgataccat ctagtggtaa gtactccttg taaactaaga ggagatgatt tcatggcaaa
    26761 aatatcaaag tacaaaaaga aaaacggtca agtggcgtgg atgtataaag gacacattgc
    26821 caccgatcca cgaactggtg aaaaaataaa tactacgaga agaggtttta gtagcaaaca
    26881 agaagctcaa aaagattatg acgagtacag acatcaaata ttatacggtg ttaaaaagaa
    26941 agcacctgat atgacatttg aagacctgta taatgaatgg ataactcatc agcgtaccag
    27001 tgttaaagct tcaacaatcg caatctcagt aagatacgca aataatcaaa tacttccagc
    27061 atttggtaag cttaaactat cgaatatctc tgtcccatat tgtcaaaaag tggtagatga
    27121 atggcacagt aaatatgaaa gttacgatta tatgagaaaa cagactgcac aaattttacg
    27181 ctacggggtt gcaatgcaat atattgacaa taatcctatg gaaaaaacac ttcttccacg
    27241 aaaaaaagag tatgagaaaa atcgtaaatt ttactcaaaa gaggagctta ataatttact
    27301 ggatgctttt aaagattttg gtaacatgaa acaatacgcc ttcttcagat tattggcata
    27361 cacaggtatg agaaagagtg aagtactcgc tttacagtgg aaagacatag acacgtttaa
    27421 taaagaacta catgtcaata aaactcttgc tgtagatgaa tttggtaaag ttataattca
    27481 atctccgaaa acaagagctt ctagacgagt tatctcttta gatactgaga ctctttctat
    27541 cctcaacaac tggaaattac agcaaaaaga agagtattta aaacttggat acaatactag
    27601 ctctaaagag caacatgttt ttacaacagt taaaaacact ctatacattc caaacactgt
    27661 taatgattgg ttaagatata ttttgaaaaa atataacttg cctcgtatta cacctcatgg
    27721 gtttagacat acacatgcta gtttattatt agaagcagga gaatctgtca aggtagttca
    27781 acaacgatta gggcatgaaa atagtaaagt gacattagac atctatgcac atattacaaa
    27841 taatgcacct aagaaaacag gtcaagactt tgctgatatg atggctcatc agtaaaagag
    27901 ctggtcaaaa gctggtcatt tctagtatat agacaaaata aaaaagctag aacccttata
    27961 taccaaggat tctagctcct ataacaagtt tatcctacac tgccttccat ctcataactg
    28021 atcaatcgat tgagttcgac tgcatattcc attggaagtt ctttggtgaa tggttcaaca
    28081 aagcccatga cgatcatttc agttgcttca gattcggtca ggcctcggct catcagatag
    28141 tagagttgtt cttctgagat ttttgagact ttggcttcgt gttctaaaga gacttggctg
    28201 ttgtggatct cattgaatgg gatcgtatcg gatttcgacc attcgtccat gatgatcgtg
    28261 tcacattcga tatgagagat cgaacccgca ctgtttttgg caaaggttac ttgtcctcga
    28321 tagtttactt ctccgccgtc ttttgaaatt gatttagaga cgatagagct agatgtattt
    28381 ggtgcattgt ggatcatttt tgcacccgta tcttggattt ggtttgctcc tgcaaaggcg
    28441 atggagagca tggtgcctcg tgcacctttt ccatctaagt aaacacttgg gtatttcatc
    28501 gttgtttttg cacctaggtt tccgtcgatc cattcaacgg ttgcgccttc gtatgctttt
    28561 gctcgtttgg ttactaagtt gtacacattg tctgaccagt tttggatcgt tgtgtaacgg
    28621 caatacgcat cttttcttgt aaagatttct acgatggcgg catgcaggct gttacttgaa
    28681 taagtaggtg ccgtacaacc ttcgacatag tggatgcttg ctccttcgtc aacaatgatc
    28741 agcgtacgtt cgaattgccc cgtgttttcc gcattgatcc ggaagtacgt ttgtaatgga
    28801 acatcgactt tgacggcttt tggcacgtaa ataaaggtcc cacctgacca tacggctgaa
    28861 ttcagcgctg ctaatttgtt gtcggttggc ggtacaagtt ttgaaaagta ctctttgaat
    28921 aattcagggt attctttcaa agcagagtca gtgtcagtaa agacgattcc taacttttcg
    28981 aattcatctt tcatattatg gtacacgact tctgattcat attgtgcgga agcaccggct
    29041 agataagctc gttcagcttc tggtatacca atcttttcaa atgtatcttt gattttttct
    29101 ggtacgtctt cccagtcacg agcgggtttg tcacttggtt tttggtaata tttgatggca
    29161 tcgaaatcga tgtctgaaag gtcggggccc catgtttgca ttggcatttt gttaaatgtt
    29221 tctagagatt tcagacggaa ttcaagcatc cattctggtt cgcctttgat tcttgacatc
    29281 tcacggatca cttcttctgt caagccttct cctgtactga aaaccggttc gacatcatcg
    29341 tgaaacccga atttatattc ttctaattct ggtacgccca tgttctcact cctcttcctt
    29401 gtggtaatga tggaaagctg cggtaccatc gttttccatt gcttttccta gtgctttcca
    29461 ggcaagtgtc gcacatttga tccgagcggg aaatttagct acaccaccaa gcatagcagc
    29521 atcgcctaat tggtcgggat ctttgacttc ttttccttgg acaagctgta gaaagtctac
    29581 agttaaatgt tctgcttctt ctattgattt tccgatgacg gcgtctgtca tcatcgaggc
    29641 acttgccgta ctgatggagc agccactgcc gtcaaaggcg atatttttga tgattccgtc
    29701 ttttacatcg acttgcaatt cgatcacatc tccacatgtg gggttgttca attcgatctt
    29761 gcttgtcgag tcagtcaagc ttccacgatg atgcggatgg gaagaatgat ccaagatcac
    29821 ttgacggtat aaattgtcta atttagatag tcccatgttg gaaaaactcc tttgttgcca
    29881 tgattgcttc aactaaacgg tcggcgtctt gcgttgtgtt gtagaaataa aagctcgcgc
    29941 gagcagtcgc tgatacttca aggtacttca atagcggttg cgcacaatga tgacctgctc
    30001 tgacggctac cccttccatg tctaaagctg tcgcgacatc atggggatgt aacccatcca
    30061 aattgaatgc aacgactcct gtccgaaaat tcgggtcttg tggaccataa acagtcaatc
    30121 catcaattgc ttgtaatttt ggcaacacat aagcggctag ttcttcttca tatcgatgga
    30181 tattgtccat accgagtttt tgcaaataat cgattgcatg gcctaatgcg atagcgccgg
    30241 cgatatttgg tgtccctgct tcgaatttcc aaggtagttc tttccatgta ctgtcgtata
    30301 attcgacaaa atcgatcatt tcgccaccaa attcaacagg ttccatttct tctaaccatt
    30361 ttcgtttacc atataaaaca ccaatacctg ttggtccgca cattttgtgt ccgctgaaag
    30421 caaagaaatc acagtctagt gcttggacat caatggccat gtgcggggca gattgagcac
    30481 catctactac gatgaccccg ccgttttcat ggacaagttc agctaattct tgaacaggat
    30541 tgaagacacc taagacattg gatacatgag caatggagac gattttggtt ttgtccgtaa
    30601 tctttttcgc tgcatcctcc atatccagga agccttcttc tgttagttcg atatatttca
    30661 agacagcacc tgttcgtttt gccaactgct gccacgggat aacattagaa tgatgttcca
    30721 tgtaagagag cactatctcg tctcctgctt tgatatagcg gtcgccgaag gttctggcta
    30781 cccaattcaa gcttgtcgtc gtaccacgag taaacagcac ttctgctgtt tcttttgcat
    30841 ggatgaacgc ccgtactttt tctcttgctt gttcataatc atgggtcgcg cgttctgcta
    30901 acgtatggac accgcgatga acattggcgt tatcgtgttc gtaatagtac gctaatgcct
    30961 ggagtacttg ttttggcttt tgggtcgtcg ctgcattatc cagataaact aaaggttcat
    31021 cattgacgtc ttgaaataag ataggaaaat cattgcgtag ctttttagca tcgatcatcc
    31081 attcaacttc ccttcgatta cttcgactaa ttctttccga acttgttcta cagggattgc
    31141 tgttaagaca gaaccgagga atcctcgaat cactaagcgc tctgcttctt ctttatgcaa
    31201 tcctctactc atcagatagt acatttcttc tggatcaact cgtcctacac tggcagcatg
    31261 tccagcagtt acttcgtttt catcgatcaa aagaatagga ttcgcatcac cacgtgcttt
    31321 atcagaaagc atcaagacac gactttcttg ttgggcatct gcaccttttg cccctttcaa
    31381 gatgtggccg ataccattaa aggtcaatgt tcctttttct cggatcactc cgtgttgcaa
    31441 aatatgcccg atcgtatgag gggctttatt ggttactcgt gtatcgattc cttggatttg
    31501 tctgcccgag ctgattgcca cgattttgac ttctgcgtgt gcaccttctc ctgctaaatc
    31561 tgagtcaaag tcagcgatca catgaccgtc attcatgaca ccaattgccc agtcgacaga
    31621 agcatctcgt aaaatgtgcc cacggcgatt catataagaa gtaatatttt ctcctaattg
    31681 atctacggct gaatatttga tttttgaacc agctttagcg atgacttcca cgatgatatt
    31741 acctgatgat tttgctactt gttctttggt tgtctggaaa cgttccagat aagaaaattc
    31801 actatgttca tctgccacga tcaacacatg cttgaagaag tgctcatcgg atgcgccatc
    31861 ttgaatgaat aaggactcga gtggttcatc gatcacgaca tttttaggca catacaggaa
    31921 aataccgctg ttcataaaag ctacatggag tgcagtcaat tggtcttcgt tcatgtttac
    31981 tgcttttttc atataatatt cttggactag ttctggatat tcgatcattg cagtgaacaa
    32041 gtcggtaaaa atgactcctt tttctgctaa ttccacaggc agttgttcaa aaatcgtcca
    32101 tgaaccttgt tggacaagca caggattgtc tttcattgca tcaaatgccg gaatcgtgcc
    32161 tgtttcactg atggtttgtg tttctttcac atcaaataac gaccagcgat ggaatttcac
    32221 ccgatcgata tgcggcaatg gcagttcatc tgctttcgct agtgcgtctt gacggaaggt
    32281 tctcatccaa tcaggttcgc ctttacttaa agaaaaatca tttaccgcgt caagataatc
    32341 gagccagttt ttttctttca ttcttgctcc cccttacgct tcttcttctt tatagtcgat
    32401 tcctaattct ttactgatac cagcgtagcc ttctgcttcc agacgtttag ctaggtcagc
    32461 attccctgtc atgactactc ggccttccat catgatgtga acgacatcag gtgtgatata
    32521 gttcaataat cgttgatagt gggtgatgat caatgcaccg aaattgtctc cgcgcatttc
    32581 atttactcct ttagcaacga ctttcaaagc atcgatatcc agacctgaat cgatttcgtc
    32641 taaaattgca aatgtaggtt ctaacatcaa caattgcagg atctcattcc gtttcttttc
    32701 tccgccagaa aaaccttcgt tcagataacg ttcagccatt tcttctggca tatttagtaa
    32761 agccattttt tcatctaact ttttcaaaaa tgccataaca gaaattttgt cgttttcatc
    32821 acgtttcgca ttgatcgctg cacgcatgaa ttccgcattc gtgatacctg gtatctcact
    32881 tggatattgc atagctaaaa ataagccaag tcgcgcacgt tcatctactt ccaagtctaa
    32941 aacatttttc ccgtcaaaca aaatttcgcc ttctgttact tcatagtttg gattgcccat
    33001 gatagcggca gataaggtag attttcctgt gccgttaggt cccatgatgg catggatttc
    33061 tccggttttc attgttaggt ttacgccttt aaggatttct ttttcctcga tcgacacatg
    33121 tagatttttt atttctaaga cagacatgca ttataccccc aaattctctt tcgttctcac
    33181 tcattttaga ctaattgaga atgaagcgca atgaccttcc ttactaaaat caaatatctt
    33241 ttatttatta ttaaacaatt ttgatttcta aattagaata ggtataaaaa agatgagaaa
    33301 taagccatta cagacttatt tctcatcttt tttgttccat accttatttt gcatcagcct
    33361 ttactggttt aacagagccg ccccatttgt ctgtgatcca ttcttggact tctttgcggt
    33421 gaagcacttc aatcagtttt ttgattttgt cactgtcttc atcaccttta cgagtcgcaa
    33481 taatattcac gtaaggagag ttgtcctttt caagcaatac ggcatcttct aatggattca
    33541 accctgcgcc gtaagcgaag tttgcgttga ttgcaactag gtcaccttca tcattttggt
    33601 acgtagaagc taaaagtgat gggtcgatcg tatggttgaa cttcaagttc ttagggtttt
    33661 cttcaatatc atcgaatgtt gctgtttcca gatctactcc atctttgact ttgactaagc
    33721 cagcatcttg tagaattgtg atgatgcgtc cccagtctga ttcagaattt gaagtaatga
    33781 ttgttgcacc atcttttaat tcggaaacat ctttgacttt tttagagtac aagcccattg
    33841 gttcgatgtg gacagcaccg gcattgacaa agtcatatcc tttttctttg atttctttgt
    33901 tcaaataagg aatatgctgg aagtaattgg catcaatgtc gccttcttcc aaagattggt
    33961 tcggtaatac atagtcatcg aatttgacga tttcaagatc gattccttca tctttcaata
    34021 atggtttcac atgttccaaa atctctgcgt gcggtgtcgg tgaagcgccg actttcaatg
    34081 tcgtgtcgtc tgctttattt gctgaatctt tgctgtcgct gttgttaccg catgctgcta
    34141 atcctacagt cagcaaaagc gctgctgcaa atccaaaaat tttctttttc atatcctaca
    34201 tccccctata tcctattatc ttttgtctgt tttcttagtt aagaaatcac cgattccttg
    34261 aacgataaat acgattagta aaataattaa agtcgcaacg aatgtcactg ttagattacc
    34321 acgctggtag ccttcctgcc aagcaagacc tccaagtcca cctgcgccga tcgcgccggc
    34381 catcgcagta aatccgatca tcgagatcgt tgtaactgtt aatccagaaa tcaatgcggg
    34441 aatactttca ggtatcaaga ccttccagat gatttcccag taacttgctc ccattgcatc
    34501 tgctgcttcc agtacaccag ggctgacttc acgaaaagca atctctacta gacgggcata
    34561 aaatggtgct gcggataaaa caagagctgg aatggctgct tgcgcaccta gcatagtgcc
    34621 tacgattgct ttagtaaatg gaatgatcaa aaccatcagg atcataaatg gcgttgaccg
    34681 gaaaatatta ctgatgatcg atacgattcc ataaatgatt cgagcatacg gtttgttttt
    34741 gcgtccaata gagtaaagga tcaatcccaa aactaatccg atgatcgtca ctaagaccat
    34801 tgagattaat gtcatatata gtgtatcaag gatagcctga ttcatcgttt ccgggttgat
    34861 ttgtttaaaa tctagatatg tttctgaaaa gcttttatcc acgatggatc acctcaattc
    34921 ctactccttg ttctttgatg aacacttctg cttgatctaa ttctttggtt tcaccagtca
    34981 tcaagacagt caatgaacca aaggaacctt ctttcacttg tttgatcttt ccatacacaa
    35041 cgttgacatc gatgttatag cgtcgaatcg cttgggaaat gactggctcg ttggcatttc
    35101 tttcgctaaa ggtcaaagtt gccaaacggc cgcttggatt ttctttgatg agttcagcta
    35161 atagttctgt cgaatcagct tctggttcga tgtcttgttg tacaaagcgt ttggttactt
    35221 cttttttcgg ttgtctgaag acagtcaata cgtctccttc ttctacgact ttccccaact
    35281 ccatcacagc gactttgttg cagattttgc ggatcacatt catttcatgt gtgatcaaga
    35341 cgatggtcaa attcaatttc ttattgatcg ctaacaataa gtctaatact tcttctgttg
    35401 tttgcgggtc caatgcgcta gtagcctcat cacaaagcag gatctcagga tcatttgcca
    35461 atgctcgtgc gataccgacg cgttgtttct gtccgccgga aagttgtgaa ggatatgctt
    35521 gtccgcgtcc ttctaacccg actaaacgca acagttcttc tgcccgttct ttacgtttgc
    35581 tctttggtac gccagctaat tccagcggca gctggatatt ttcaagtaca gttcttgacc
    35641 ataacaggtt gaaatgctgg aagatcatac cgattttctt tcggaatgta cgtaattctt
    35701 tgttttttaa ttttgtaata tcttgatcgt ttacgatcac ttcgccgctc gtgggaagct
    35761 caagtccatt caggagacgg actaatgtac tttttcctgc gccagaatag ccgacgattc
    35821 cataaatatc ccctttttca acgtttagtg aaacgtcatt gacggcttgg atgtttccgt
    35881 ttttcccatt gaatgtcttt ttgacattcg ttagttggat taatgacatg ccattcacat
    35941 ctttctctta tgatttttca aacaaaaaag ccttcgccct cttgccttaa gcaaaaggac
    36001 gaaagcttga acttccgtgt taccaccttg atttaccgtt acttcgcaat aacagcctct
    36061 tccagtactt ggacttagct tctttccgta tactgtcgcg ctgtaacggg cactcccgta
    36121 gtaagtttgc ttacgctcgc ttactctgct ctaagaccat cttccatctc attttcgtta
    36181 cccattttca gcaaacaggg ctctcttcaa acgtccgtga catgtactct tcttttcaaa
    36241 gctttctcgt ttcatatagg attgcttatg attatagcaa ctggaagaat cagtgtcaac
    36301 ttttttcaag tgattttctg attttataat tcgtcaaatt cttttggatc aacatctttg
    36361 aaacttaaga tccacgcatt catttcatct gaatcattca agatattgat atcttcaccg
    36421 attttatcat taacagaaga aactgtaccc gttagcgggc tggcaaattc attgaccgct
    36481 ttttccgctt caacttcgat cagaggttca tcttttttta gcgattgtcc tgcttttggc
    36541 agattggcaa acgtgatgtc tccaagttct tcttgcgctt catttgtcaa accaacacag
    36601 tattcttttc cattaaataa gatccaaagg ttgtcctttt tcttcaaatg cttgcctgcc
    36661 attttatatc agttctcctt cataaatttt ttcattgaat ccaattgcaa caagctggtc
    36721 ctctcgtaag atcagtggtc gcttgatcag cataccatct gtcgataaga cttggctcgc
    36781 ttttgaagcc gtaaactcgc ctacttgatc tttcagtcca agttcccgat atttcatccc
    36841 gcttgtgttg aacaggcgac ggattggtac ttgactcgtt tctagccaag tctcaatcgt
    36901 tgaggccttc ggtacttctt tgatcatatc aacggtttga taactaacgc catgctggtc
    36961 taaccacgct ttggcttttt tgcatgttga acatttcggg taccagtaaa aggtgtacaa
    37021 ttttcttacc tccttgaaga tcttgcaggt gcttcatttt ggtatctcat cgataatatc
    37081 aacccgatac cgatcatgtt ccctaaaatc gaggatcctc cctgactaat gaaaggcaat
    37141 gggatccctg ttaaaggaag taatccgata tttgctccaa tattctcaaa gacatggaac
    37201 agcagcatca tgatcaaacc gcttgcgata taggcgtaaa attcattatt cgtatcgaaa
    37261 cacacccgaa tcatacgata gattaaaata aaatacaaga aaatgacgaa tgcaccaccg
    37321 ataaagccga agttttcacc gataacggta aaaatcatat cggactcacg aacaggcaca
    37381 tagatattgc ttacgttgaa tcctttacca aacaagccac cggtaccaat tgccaaaagt
    37441 ccttgggccg gctgataact cattcctgac gtatcatgga aagggtccag ccatgaatca
    37501 atacgtgcaa actgataaga tttgaatcca actttataaa gcaagtctct tccgccttca
    37561 gtcgtaacca agaagatcgt tcctgctcca acgactactg ccaagattac tacaggtgcg
    37621 atgatgcgcc aagagattcc agacatcagg aaaatcccgc caaagatcgc aagaaagaca
    37681 agcatcgttc caaagtcatc ttgggccatg atcaatgcta aaaccggtat tgtcacgatc
    37741 aagagcttcc caatcagcca aaagtccgat ttcatcgtcc gttcttttac ttgcgtatta
    37801 tgtttagtta cgatcagtgc catcatcaag atgtacgcaa tcttcatcaa ctctgctggc
    37861 tggaaagtaa acgcaccgaa tcgaaaccag tttttagacc ctgttgaagc agctaaattc
    37921 tgatcataga atttgagcaa gagtcccatt accactaacc ccaaaccata aaggtaagga
    37981 gtcagtttcc agatccattt ggaattcaaa tgcatgatga caacgattgc tgccgctcca
    38041 actaaatacc agacaacttg catccctacg cctttcaaga ctgctggatt gttcggatca
    38101 tggctaagtg ctacatataa tgagagcaga ccaatcaaac ataacagaaa gactggtaaa
    38161 atcacgccat aatcaatacg attatcgttc gaagctttta attttttttc catgtttcat
    38221 cccttttctt aaaaaccata ctgctgatta ttatagcggt ccagttagat aatggaaagt
    38281 ctttccatag acatttggga aaaattaact ttccgtttgt gcagttgctt gagcaaatgc
    38341 agtacaaaag cctactgctt atctttagtg tatcatagaa ctttttttga tacatgcaat
    38401 tatctaccag ctgagattct cctcgctgtg agaagtttct gtgctttcat tgtatcgaag
    38461 gatctcttcg gcaatctcta gcagctgatc agaaaccaga ttggttcgtt ggatgaaata
    38521 aaaatatcga tggaaattca acggagtcat tggcacattt tctggaacag agcgcttaga
    38581 caaaatcgag cgaccgattc cttccttcag caacgcaaca attacatcgt tacttttcac
    38641 gatcatcttc ttatcttgga tattcatctc ttcaaaataa cgctgcgtgt aatgaaaaac
    38701 accagagttt gcttctctta caagccacaa tttgcttttt gggtccccag cgatgactag
    38761 ctggtcttcc atcaaagagt atctttgtac gccggaagtc tctaatggct tttcgataaa
    38821 accaaaatcg gattcatgtt tcgctacttg ttctaatgat tcatgagaat tcgtgatttc
    38881 gatctcaaaa tgcactttag gaaacctttt gatcagatgt ttcatcaact gaggcaaaag
    38941 atagacagca aaggtgtggg aagcaacgat ccgacatact tcttcttcat tttgttcatt
    39001 gagcaatttt tgctgagttt cttcccattc ttctaacaaa accagtgtcc gttcatataa
    39061 taagtcggct tgcttagttg gaagcatctc ttttcttccg ttacgttgaa aaagatcgat
    39121 attcaattcc cgctccaact gtttgatttg attcgagact gctggttgag ataaaaacag
    39181 tacttctgct gctctggaaa aatttcttgt ttcatatact gctcgaaaag tcgttaataa
    39241 cttaaacatg gcaccacttc cataactttt tatgataatt actataaaaa ctatttgatt
    39301 taaatataca aaaaaccatc tataatagaa atgtacaaca aaacagttgc tgatccaact
    39361 agtaacttag atgaagacaa tcagctgtct gcttgctcgt aatcatacat tcctattcat
    39421 tttacaatgt attcgttcat cttggtacta aaatctatta aataaaaagg agaatattat
    39481 atatgaagaa ctttttgaaa attattccga tcccgatctg cgggttgatc cttgggttag
    39541 cttcccttgg aaatctgttt aaagactatc accatgttgc tttaggcaat ctaactggcg
    39601 gtatctctat gattcttatg atattcattt ttgttaaatt gtttatctta ttcgaacaca
    39661 cgaaacaaac gttgcatgat ccaatcatcg cctccgtttc accaactttt acgatgtcac
    39721 tcatggttat ttgtacttat tttgtttcat atgaaagtat tgcaccaatt gtcaaattca
    39781 tttggctgtg cgctgttatc ttccaagtga tccttgtctt ttatttcaat tatcaccatg
    39841 ttatcaaagc tgatctttca attgaagcaa tttatccaag ctggtttatc atttacgttg
    39901 gatttggggt catcactgta actgccggga acttcttccc acttattgga aaaattttct
    39961 tttggatttc attgatctgc tatgcgttct tattgccgat catcatcaaa cgtgtctttt
    40021 tcgtaagaaa tatggctcat ccgacacgtc cgctgattac gatcgttgca gcacctggtt
    40081 ctctttgcct aacaggttat cttaaaaact ttgctgaacc taatttttat cttgtcgtag
    40141 cattgttcgc tttatctcaa gtattgtatt tcgttgtgct gtctatgctt ccacgtttgt
    40201 tcaagcttcg tttttatcca agctatgcag cctttacatt cccgcttgtt atctctgcaa
    40261 cagctatatt tactactgtt cattacttca acagtttagg tatctatagt agcgtattgg
    40321 atttcttaaa agttgcggaa tgtctgtttg caagtgtagt tgtcttctac gttcttgctc
    40381 attacgtacg tttcttaatt aaagaacata gcaaacatgg aaaatttgtt tctaaaaaaa
    40441 tcgcttaata atcgattcaa taggttgtga aaaagctgtt ctgcatcaag taataagaac
    40501 ggccaaacaa aaacagctgt tcatgttttt gtactggttg ggcttattac cgcagatgca
    40561 agcttttgaa caccgtttac caagaggtcg taaaagaagt ggtcagcttc aagaaataag
    40621 aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ttcggcttat ttccgtagaa
    40681 gctacttctg gaacaccgtt tattcgaaac aagaggtcgt acaagacttt tgtcacgacc
    40741 tcttgttctt ttgtcaaaat actggtttag tgctactatg ttcgagtatg cttttagtat
    40801 ttattgacga aaggaaccga tcaaatgaaa tcattgtcac atccaataaa atctgtaaag
    40861 gattcagcgg tccgcgaaat cttacccggt ttactgcttt cttttgccat cgctgccttc
    40921 agcaggcttc ttgctattta tctgccacag ttaggtggag cgactattgc tattttattg
    40981 ggtattttat taggaaatac tttttttaaa cagcctgttc tagcaatcgg cacaaaattt
    41041 gctgaaagca aactattaga attctctgtt tttttactag gtgcaactgt cacagctcaa
    41101 acgattgctc aaattggtgt aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact
    41161 atcatcggtg cttacttgat tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg
    41221 atggctggag gaaacgctgt ttgtggttct tctgctattg cttcaatcgc cccttccatc
    41281 catgcgaaag aggaagaaaa aggacagatc atcacactag tcaatctact gggtactgtg
    41341 atgatgttga ctctcccttt tcttggatta cagttgtttg gtggaaatct cattgaaaaa
    41401 agtgcacttt tgggtggtac actccaatct gttggtcaag tagtcgctgg ggcaagctta
    41461 cttgacaatt ctgttgtcga attcgccatg ctatttaaga ttctacgtat tatgatgctc
    41521 gttgttgttg tctatctgtt tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa
    41581 acgccaactg atacgcagaa aaaacgaaaa ttaccgcttc cttggtatgt attagggttt
    41641 gtgatctttt gtttggtcaa cagcttgttt tctttacctg tagttattga ccaatcggca
    41701 cattttatca gcagctggtt tgagatcact gctttagcgg caattggtct gcgtttagac
    41761 tttgcaaaat tcatgaaaga aggtacacgc ttcttatctt atggattagc tgtcgggctt
    41821 ctccaaacag tgatggcttt actatttatt tggctgatca aagtttagaa tgaacatgaa
    41881 aaaacagttg tgattctcgc atggaacaat gtccgaatca caactgtttt taattttgca
    41941 gatatccttc taacaacaac aattggcgtt tgatttcaac cccatctatt gcgtttccca
    42001 tatatcctgt cagttttcca ttttgcccga tcactcgatg acaaggaata acgattggca
    42061 atggattggt tcgatttgcc tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa
    42121 cggctacttc tttatacgtt cggatttctc cataaggaat ggtcgacaaa gctttccaga
    42181 cattttgctg aaaaggcgta cctctcttta tagataaagg aacatcaaat tcttttcttt
    42241 ttcccgcaaa atattcttca aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg
    42301 attcgctttc tgaaattggc tgaaaagata cagcagtcaa tccggattca tctgcatcta
    42361 accataaaaa gccgataggt gtgtgtattt tcattttgtt tgctcctagt caatagactg
    42421 gaacttcctc ctttttctct atccaaaact acttgccaac taataaaaat tgttcttaaa
    42481 agtttgataa accgaggaaa catggtaaac taaatacgtt agtttacaaa aagaatacct
    42541 gttcttttac gtaaaatcaa attttaaagg tgttatttaa ggtttattaa attttgaatg
    42601 taaaccatat ataaacatac gattgaaagg atagaaacga tgaaagtatc aattgttgtc
    42661 ccatgtttta atgaagaaaa aactgttcct cttttttttg atgaggttga aaaattcaaa
    42721 ggtgcccatg agttcgaata tttgtttatt gacgacggat caaaagacgg tacgttagca
    42781 gcaatcaaga agctagcctc agcttatcct tatgtccgct ttgtctcatt ttccagaaat
    42841 tttgggaaag aagcggctct gtacgctgga ttgcaagctt ctacaggaga tttagtgacc
    42901 gtgatggatg ttgatctgca agatccgccc gaactgcttc ctgagatgat caaccggatc
    42961 actacttctg atatcgattg tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg
    43021 atacgcagtt tctttgcgaa aaaattctac cagttgatca ataaaatcag cgatacagaa
    43081 atggtcgatg gcgctcgtga tttccgcttg atgactcgtc aaatggtgga tgccgtccta
    43141 gaattaacag aatacaaccg attttcaaaa ggattattta gctgggtcgg atttaaaaca
    43201 gaatatattt cttatgaaaa ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg
    43261 aaattattca actactcgat tgatggtatc gtgaacttct cggatgcacc gttaacgatt
    43321 gcttcattta tcggcgcttt gtcttgtgtc ggttctggta ttgcaatttt gttcattatt
    43381 ttgcgggcat tgttgtttgg tgatcctaca tcaggatggc cttccatggt ctcgatcttc
    43441 ctgttcattg gtggaatcca attgttatgt cttggaatca tcgggaaata tattgggaaa
    43501 atcttcttag aaacgaaaca gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag
    43561 ccaaatgaat tgaagcctca ccaataatat acgtcaaatg aagtaaacat ttttttaaat
    43621 gaaaaaggac tgtgacaaaa gtcttgtcac agtccttttt tccgaataaa tggtgttcca
    43681 gaagtagctt cttcggaaat aagccgaaat ttcacaaaaa tttgagaagc aattttcgta
    43741 aattccttct tatttcttga agctgaccac ttctatcaca acctctttca tatcttatta
    43801 cttcttcatt gctgctttta gtgctgctgc taatgggctt tcttctggtt cttctgcttg
    43861 tgcatatttt ttcagcaagc gtcgttcttc atgtttggtc attttcttct tctgctcttt
    43921 tttatcaagc aatttttctg tcgttccatc gtatttacaa cggaaataag caccgttttt
    43981 accttcgatg atttccattt tccggtgaca ttgcgggcat cgatgattag agacttttgg
    44041 atcttttctt ctgcggtagt tgcaatctga attggtgcag acatagattt tgccgtcacg
    44101 tgtgtttttc tcgcgcagat tggccccaca ttctgggcat ttcttttggg taatcgagaa
    44161 atcttgatat tcttgtttgc ttgatttgat ctcattcacc aagcgttttg tttctttttc
    44221 gattccattc aagaaggttc ctgcttgttt ctttcctgca gcaatagctt caaggtcttt
    44281 ttcccagctt tctgtcaaat ctggtgttac taaagaggga tttaccaata ctaataattg
    44341 cttaccttta ggagatactt gcagtccttg aggggtacgt tccatcagtt cagatttgat
    44401 tagtttctcg ataatctctg cacgcgtagc tggggttccc agactgtatt tttccatttg
    44461 accaagcaag cttgcttctg acaatggttt aggcggtgca gatagttctt ttttgatggc
    44521 gaaatcggga ttgattctca ttcctttttc ccatttgact gtttccgtct cagtttcagt
    44581 ttcgcctttc catcctgctt ggacgacacg attttgccga aaaatgaatc gttctttacc
    44641 aaattcaacc gtaacttttg tttggctgac tttatggggt tgagcaaaca gtcctaaaaa
    44701 acgagagaca atcatttgat agatttttcg ctcttcatta cttaattttt cataacgtgc
    44761 tctgttttca gttggcaaaa gtgcatggtg atcggtcact ttactgtctt ggaatacttt
    44821 tgtctgttgg acgatggctc cgtttttcaa atactgcttg acctcaggag caaagtcgct
    44881 gactgcttgc aatcgttctt tcatcgtact tttcatgtca tttgtcagat atttgctgtc
    44941 tgtacgcgga taagtaacga tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt
    45001 tttctttgca gaatagccat agcgttgatt ggcttctctt tggatctctg ttaaatcata
    45061 aggcaatggc gcagattccg tttttaattt ttcttggact tctgtgacag ttcctttgct
    45121 tgtactgatc aattgaacaa gtttttgtgc ttcttcttgt gtttttaaag caaattgatt
    45181 tttttgaagc attttggctt gttcttttcc agcttgcaac gtgatcgtga aatacgtttg
    45241 tggacggaac tgctcgattt tcttttcttg gtctctcact aatgctagtg tcggtgtctg
    45301 cacacggcct gctgataaat tatccgcgta cttcacagtt aaggctctgg tcacattcaa
    45361 tcctaccagc cagtccgctt ttgcccgggc aagagcagat tcatacaatg catcatattc
    45421 tttcgcaggt cttagttgct tgaatccagt tttgattgct ttatctgttt gagaagagat
    45481 ccataaccgc ttcactggtt tattgaaatg cacatactct aagatccagc gagcaacaag
    45541 ttccccttct cttccggcat ctgtcgcaat gactgcttct gagacatctt ttcgctgagc
    45601 cagctgcttg attgctttta attgatgtcc tgttttagga agtggtttga ttcctagttt
    45661 tttagggatc attggcaacg tgtccatttg ccagctctgc cattccttat tcagatcttc
    45721 cggcattttc aatcctaata aatgaccaag ggcccaagta acgatcacct tgggtccttc
    45781 ataataattt ttgtgctttt gattagcacc aagcaccttg cttaggtctt tcgcaacgct
    45841 tggtttttcc gctagaatta gttgtttcat aaaattcctt tctgctttct actgtgatgg
    45901 gctgatgatt tttcaacaac gcaagtccct tgtattgctg taaatcatcg tcacactctt
    45961 cacaccagcg ctcatctccg tcattccaaa aggcgctgag aaagttactt tttgcattga
    46021 tatattcata attttgatgg atttcgttcc attgtttttc gtacgcttgt cgtgcttctt
    46081 cgaaagactc gaatgtttct tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc
    46141 aaggctcatt gtccccgaac atggtaatta cttgatacat actcgtgctc cttctttcag
    46201 cttttctaga ctcatcttag tcacttttca agaaagttgc aagaattttc tcttataaaa
    46261 gggtcattta atgaacatct taaaattgtt acaaatgaat ctgattgttt aaggcaaagt
    46321 agcgataaag ttattgatca tccaaaaata gctgtcttct ggatcgattg ttggttcttt
    46381 tgtaaagtat cctaaaaaac gtaaggaaag ataaccgtgg atcatactac gaagttccct
    46441 gcttcgatga actttttctt ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat
    46501 ctgattcgtt tcatggattc catctaataa aacagcttca ttggtatgcg gtacactgat
    46561 cagtaactca tacactgctt gatttgaaaa agcaaaggat cgataagttt ctgcatagat
    46621 ctgcagtgct tcctgaccac tttttcccac aagagcccgt cgcagctggt cattaagttc
    46681 ctgcagaagt ttcgctgtta gcgctgtttt gacatcacga atatttttga aatggttata
    46741 cagcgaggga gccttgatat ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac
    46801 atccatctct tctgctagtt ctcgaaagca gtcgatgatt ttctcttgag acagatttct
    46861 ttttttcatt tccatgtttc ctctcataaa ataaatcctt cactctttca gtttaccacg
    46921 aaaaagaaag agaaaaaaga gactttcatt gataaactac atattgtagt ttataataaa
    46981 gagctgtaga tgaaaatttt cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa
    47041 aattatttag gaaaagagaa acttgggaac aaaacttgtt tgtcttatgg tttggaacat
    47101 ttatggctgg tatcggattt agtttagtca tgccttttat gtcactttac atagatacgt
    47161 taggtaatta tagtacgtca caattgaact tttggagcgg attgactttt tcatctactt
    47221 tcttggtgac tacgcttatc tctccttggt ggggaaaatt agccgaccaa aaaggaagaa
    47281 aattgatgct gttgcgtgct tcattaggaa tggcaatcgt catttctttg atgggttgcg
    47341 tgactagtgt gtatcaatta gtcgcattgc gtctgcttca agggattttt tctggttata
    47401 tcagtaatgc cactgccctt gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc
    47461 ttggaacctt agcaactggt tctgttacag gaacattact tggaccgctt cttggcggga
    47521 tctctgcttc agcgtttggc tatcgcccta cctttttcat tacagggatc atcttatttt
    47581 tcgtcttctt gttgagtctg tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa
    47641 acatggtttc tgccaaacag attttcaaag acttgaaata tccacacgtc gtcatcggta
    47701 tgttcgtcac aacgatgatc atccaagcat ccaacaattc cattagtcca atcatcagtc
    47761 tgtacattcg ccaattgctg catggacatg ggaatgttac gttgatcagc ggaatcattg
    47821 cttcgatacc tgggattgcc actttgatag ccgctccaag atttggtcgc ttaggtgaca
    47881 agattgggag tgaaagaata cttgcgattg gtttgggttt tgcgattctg gtttatatcc
    47941 caatggcatt cgtcacgaat gtttggcaat tagctgcctt acgttttttg attggtatct
    48001 ctgatgcttg tctgctccct gctgtccaag cattgatcac aaaatattcg cctcatcaag
    48061 ctgctggacg gatcttcagt tataaccaat ctttccaagc aactggtaac gtagtagggc
    48121 ctatgatcgg ctccagtgtt tccagtgcat ttggttatcg tggcgtcttt ctttcgactt
    48181 ctcttcttgt tttggtcaac ttcttgcttg tacgacacaa tacacaagag atccatcagc
    48241 aagaaactgc agaagaaaaa gcttcaggag tctccatagc ttcagggcac tctccttctc
    48301 atagacaata agcgtaaatg aaaaacactg cttgaacagt tgtcacagac tgtccttgca
    48361 gtgtttttgt ttaggcctgt tttttcaaga actcagataa gaggaataat cccttttcca
    48421 aggtttcttt tttacaacag taacctagtc gggcatgctt cggtaaatca aaggcacttc
    48481 ctggtactaa tagtactcct gtttcttcta ataaattgat acaaaatgtc tggtcatctt
    48541 cttcgatggc taatttaatg aaagaagtag agacgtaatt gggagcgaca agttcaactt
    48601 tcggttcatt ggctacccat tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt
    48661 ttcgcgccaa tattttttct ttattcttca atgcatgtac agcaagatca tctgacagga
    48721 ctccgccgca aatcatcgtg tagtctcgat actttcgaaa aacttctgcc aactcaggtc
    48781 cagtagctgt ccagccaata cgaatacctg gaatggagta ggttttggat agggaattgg
    48841 ttgctatacc tttttcatag acatctacga tcgacaagaa ttcaccttta tccgttaaag
    48901 gcgcatatac ttcatctatc aatacatatg catctactgt acgagcaatt tctgcgattt
    48961 tttctaaagt tttccgatct agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga
    49021 tgatttttgt ttcaggtttg actaaggctt ctagctgttc taaatcaaac tgccaatctt
    49081 cttcttcctt caaatgaaca aagtcaacag cggcacctaa agatttgggg atgtcatata
    49141 attgctgata agtaggaagc atcgaaacaa catggtctcc tgcttccact aacgcgtata
    49201 gagctaaaag attagcacca gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg
    49261 tttgataaag agaagcgact tcttgtttga aaacatctga tccttcgatc cagccatagt
    49321 ccaatggttc gtttttgcgt ttttcgaaaa atttacttac gctagtccca tctaagccaa
    49381 cgagttcgtc taatgtcaat gcttcgatcg agctttgtgc aatatcatat accgctttct
    49441 tttcccattt atttagccat tcttctacac cgaaatttgc gattttcatg tttctttccc
    49501 ccttatatct tgatccagcc tacagcaagc aacccgattg aaagcagtgc ggccacacaa
    49561 atcagcccaa tcattacttt ttcttttccc gtaatttgat gtttggtttc acgacaagcg
    49621 atccagtaga agcaaaaacc aggaagatag gcaatactac ataaaaggac ataagaaaat
    49681 cctgctaaaa tgatgcccat caattcaaaa actacagcaa tcccaccgat cactacttgt
    49741 tttttgattc cttcttttaa agaaaactgg acttgataga tcccgacaag tagataacaa
    49801 atcaaaattg ccgctgtaca taaagaatag gcaaattgat aggcataatc agtaactaag
    49861 aaagtcaata agaatagatt agtcaagatt gcagtaacaa ctaacgaata agttggggca
    49921 ttttttttat tcgtttttcc ccaacctttc ggcaacagac cgtctcgagc catcaacatc
    49981 gttgtttctg ctgggagcat cgtccaagac aaccaagaac caatgatcga aataatcaag
    50041 ccgatattga tcagcgctgc tccccaattt cccacgattc cttttaaaat atttgccata
    50101 gcaggttgtg aaatagttgc taactcttct tgagataaga cgccgtatgg caagatcgaa
    50161 gcaaggatat agataaacaa taaacaaagc agaccaatga tcgatgcttg ctgggcttct
    50221 gaacgtttct tcgcgcggtt ggctaaaaca cttgcgcctt cgatccctac aaagacccac
    50281 atcataacca tcaaacaacc tttaatctgc aaccagatcg ttccttgctg ccctgttcca
    50341 ttcactagat tatcagatac gttaccccaa aaatcagcag tgaatatatt cactttaaat
    50401 gcgataaata caaatattaa aaataggaat aatggcacta atttacagat cgtcacgatt
    50461 gtattgatga cgctcgctcc ttcaactcca ttgtttacta ataaagtcag accccaaata
    50521 aaaatacttg caaataaaat agaaggaaca ttttgtccac ctttgaatat cgggaaaaat
    50581 tctcccatgg cgctcatcag catcgttgca aaagcaacat ttcccagcca cgcagacaac
    50641 cagtaacccc aaccactgat gaagccacct aatttaccaa atgaagcttc cgcgtaaccg
    50701 aaaataccac catctagatc tggacgcttt tctcctaaat gattcagcga taataccaaa
    50761 gctaaaatac caatcccaac gattatccat gaaaggatcg ctggccctgg agctgcagaa
    50821 ctagccagat cacttgtgat cccaaacaca ccgcttccga ttgacgaact gacaaccaga
    50881 gcaaccagtc cccatttgct aatacccgtc gatttctttt ccatttccat caccctcact
    50941 tataaaattg aacaaatcac ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt
    51001 aacaaaaagc aactttattc atattattgg atattatgaa ctttttacac aagtatttca
    51061 agtataaaat gaataaaaat taattttatt gcaaaaaaac agctatgcta tccaaaagaa
    51121 aaggtgtttc ttttgttagc catagctgtt ttgattcatt taatatcgct taaacgtatt
    51181 gtaaaacttt tgtttcttga tatgcgtggt cgatcaaacc accacccaga cattccattc
    51241 catcataaaa tacaactgct tgtccaggag tgattgcacg tacaggttcg tcgaatacga
    51301 cttctgcacg attatcatcc aataagcgaa ctgtcacagg aacgtcttgc tgacgataac
    51361 ggaatttcgc tgtacacttg aattcttttg gcattggttc attcgtcgta aagtggattt
    51421 cacttgcatc caagcttgtg gcatacaatg caggatgatg gaacccttgc cccacatata
    51481 atgtgtttgt cgctagatct tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc
    51541 caccgatccc tagtccttga cgttgaccaa tcgtataata tatcaagcca gcatgttgtc
    51601 ctttgacttc accatcaaga gtgaccatat ttcctttttt tgctggcaga tagttgctca
    51661 aaaattgttt gaagttcttt tcaccaataa agcagattcc cgttgaatct tttttcttag
    51721 cagtcgcaag gcctgcgcgt tcagcaattg cccgtacttc tgatttttcc atgccgccta
    51781 gagggaacat cgtttttgaa agctgttctt gtgataattg gctaaggaag taagtttgat
    51841 ctttattatt gtctactcca cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt
    51901 gcgcataatg tccagtagct acataatcgg cgccaagatc cattgcataa tccaagaatg
    51961 ctttgaattt gatttctttg ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt
    52021 attcggctag gaaatattca aatacacgat cccaatattc tttttcaaaa ttcacagagt
    52081 aataaggaat cccgatttga gcagctactt tcgctacatc cttataatct tccgtggccg
    52141 tgcatacacc gttttcgtcc gtgtcatccc aatttttcat gaatattccg atcacgtcgt
    52201 atccttgttc ctttaacaaa agtgctgtta cagatgagtc gacaccgccg ctcatcccta
    52261 cgacaacgcg tgttttgctg ttgtctgtca tgatatcacc atcatttcaa ttagattctg
    52321 aaacatctac gagttgaagg tcgcaacttt tcagtatttt acattatacg tcatatttct
    52381 gaaaatttca tcccttaatt atcaagtcgt aaaaatactg ttctactgga cctattcagt
    52441 acacaaacat gatagtcaac caaaaaatca ctcatctttt gagcattcga tataaaaaat
    52501 tggcatactc ataaaaaggg ccagcctttc ggcaataagg aataatttta taaattgtga
    52561 aaaactattt ttcaaaattg cttcttatcg cttaaagctg cacgtctcat ttacaacctt
    52621 ttctttttag atgttatgag ttgctcagat aagtgatttt gtttactcta agaaaaaagg
    52681 gaggcaaaag atacatgaat tactttatca gtgatatgca ctttttccat gaacgcttat
    52741 taggaaaaaa cgactttgct ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt
    52801 tgatcactag ctggaatgca gtaataaaag aaaccgacca tgtttatcat ctaggcgacc
    52861 ttgctatgca tccgcaatat gaaaaagcaa atgcagaaat tttggaactg gtcactcaac
    52921 tgcaaggaac aatccacttg atcaaaggga accatgacag tcgcgctttt ttccgttatt
    52981 tagaaaaaaa tgatcctagg cttactgacg gaagtcccaa attttatttt tatgatgtag
    53041 gtgccatcgt taaattcgac catcaacaat attacttgac tcattatccg atgttgctcg
    53101 ggcctaacga cactatccgc aatcttcatg gacatatcca tcattacagc gtacctatcg
    53161 agaacgatgt caatgtaggc gtagacgcac cggaaagaga actcttaaag gaaaaactac
    53221 catttggcac tccgttatct gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt
    53281 acgataggtc gtgaaaaaac tgccctatat caagtattaa acaaataaag ataattactc
    53341 atatttttca tttgagtagg cttattgcca caggaacatt aggatcagaa atggagttgt
    53401 aacaagactt ctgtcacaac tccattccat actattcgtc tttttgctca tggtgttctt
    53461 ttaccagttt tttctgtaat tctttatcat aatttcgggc agctgacgtt aaaaataaaa
    53521 cgattccgca taataaaatc ccgattccgg aaaacaagaa cattttttct acccctaaac
    53581 gatcagctaa tggtcctgca aataataatc caattggacc tgccaggttc atcaaagagt
    53641 tgaagttccc taagacacga cctaaaacat tcgattcata actctgctgg atcattgcca
    53701 tcagcagtgt attgaaatat ggcgttgcac aacctgctcc tgcattcaag ataagaaagt
    53761 acaagaaccc ttgactatcg tttggaacca atccgcttgc accgatcgtc aggcccataa
    53821 tgatgtaggc tataataata ggtttcattc ggtctttcca tgttcctata aaactgatca
    53881 gtgcaccgcc taagagcatt ccgactgcgt agactacttc cactgctccc gcctgtccaa
    53941 cggaaccacc aaagtaatct agcgtcatca atggatacag actgattgct ggcatgaaca
    54001 acagcatcac aaatgcacca ttgatcgtta tgtaccataa ccctttatta tccatcaatt
    54061 gctgcagccc aaattttgca tctttaaaaa tagtaagcgg aacttccaat atttcaggag
    54121 aaacttttgg gatcttcaca aaaatcaata agccgacacc aaaaactgcc cccaatacat
    54181 ctaataaaat aaggtaattg acaggaacga ctgaaaacaa agccgcacct agagctggcg
    54241 caatgatgaa attcgctgat tggaccattc ctaactgtcc attcgtcctt gttatgtgag
    54301 aagatggaac gattgtcggc ataatcgact ggatcgttgg catttggaat gtttgtgcga
    54361 ccgaacgcat aaacaaagac acaaaaacta gccaaatcgg gaaggattct gaaatcgttc
    54421 cgactactgc taaaataagc gcgaaaatcg ctacaataat atccgtgaca atcaaaagag
    54481 cttttttatc ccagcgatcc actagcggtc ctacaaatgg gcttagtaaa accatgggaa
    54541 tcattcctag taaagtagca aaactcaaaa ttgtcgccga accggtttct cttgtcaaat
    54601 accagatgat cgcatattgg acgaccatac tagtgattcc tgacaaaaac tgtcccgata
    54661 aaaagaacaa ataatttctc ttccaattcg ttaaaacgac cgactgttca ttttccataa
    54721 acatccctct tttctttttc attttgtata gcgtttgcac aacaatcatt atacgggatt
    54781 cttttttcaa aaaatacctt tttccctaaa taacaatcgt ttcaatttaa atttctttac
    54841 ttagaaacaa taaatcagca aaatattaaa aataacaaca tgtgttaaat ttaaaaataa
    54901 aaaagacaac taatttgcgt cgtccttaca aagttagtca tctaacaata ggccgtttca
    54961 aaactagttg tctttttata tccacagatc attcgacttt ttcgaataac ccacggctaa
    55021 tcatcccatc catcagaaaa taaaatttat cttggctcat tttctgtttt ggatctttga
    55081 aaatattgac tgctttcaat ccatttgctg tagtgatcga cattttcaat gtttgaatat
    55141 cttttgatac agtgattttt aatttgaatc cttctttgct ttgcggcgtg gcatctaatg
    55201 gtcggatcaa ttgataattg cctccgtttg tttctgtaaa tccattatcg cgcaatgtat
    55261 atctttttgc atcaggatgc aaacgatagc taattggtgc gcccagtacc gttgctgttg
    55321 tttcaaatgc catgattttc acctcgataa aattagtttc tctttattat aaaagtttat
    55381 cctgattttt actaggtttt tcagttaagt tccctaaaaa atgaaggcgt tctctcagac
    55441 atctgttcat ataagaatga cttcactagt tattttttga cagcacgaac taattgatca
    55501 aggaaatact ggatgtcgtc ttcggtattt cccaaaccaa agctgatacg gatggattct
    55561 tttagtatcg gtgtatcttc tccatacatt gcttctaata cgtgtgaagg ctcgatattt
    55621 cctgctgtac aagctgaacc agtagaaata gcgaccccat taagatcaag cttcatcagt
    55681 agcaaatcat ttgcttcgcc aattaagcga agattcaaca catgagggag tttattcgtt
    55741 aaatcaccat ttacttgata agggatttcg tttgcttcta atgtatcaag aatcaattgc
    55801 tggaatcctt tatatttgtt gttacgtgct tcacgttctt caggtgacag cagttcaact
    55861 gcttttgcca taccccagat ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc
    55921 tgctccccgc ctaaaagcaa tgcagggata tttactccgt ctcgtttata taagaaaccg
    55981 acgccttttg gcccattgat tttatgagca gagatactta ataaatcgat tcctaattct
    56041 tctggatgga tcgtttggtt tccgtacgct tgtaccgcat ctgtatggaa ataagctgga
    56101 tgatccgcta aaagttcacc gatttctttg attggcatca aatttccgat ttcattgttc
    56161 ccgtacatca cagagaccaa gatcgtatct tctcgtaacg cttttttgac ctcttcgatc
    56221 gacagattcc ctttttcatc tacaggcaga tatgtaacgt caaacccctt tgtctctaaa
    56281 tatttcatgg tattaagaac agcaggatgt tcgatagctg tagtgattag atgtctgcct
    56341 tctttttgac gcgagaacgc tgtttctaag atagctgtat tatccccttc tgttccccca
    56401 ctgttaaaga tgatctcgtg aggttttgct tgcagactgt ctgcaatgat ttgtcttgct
    56461 gtttccaatt tttcatgcgc gtggcgacca aatccatgta tgcttgaagg atttccaaac
    56521 gtgtcttgca tgattgccgt catcgcttca attacttgtg gatgcatggg ggtagttgcc
    56581 gcatgatcca gataaatagt tttcacttca ttcatccctt ccaaattatt gctaggcaca
    56641 ttctagcata aaatagcgaa caaaccaaag aagagctcat ttttgtctag aggacgtttc
    56701 atgggcatag aaaaaaggag ctgtgacaaa agtcttgtcg cagctccttg aagctgctca
    56761 cttctgtcac aacttctttc cctctttttt ttgtttattc gaattctttt tcttccagac
    56821 ggaataacgg actcatcggt gtattttcat ggatgcgttt gaccgcttca cccattaatt
    56881 ctgaacatgt aacgattgtt aagttttctg gatgacgatt ttcttctgtg aaaacagaat
    56941 cagtgataca aatatctttg attggtgcat tgtctaaaat acttttcgca tgatcggaca
    57001 ataatccatg tgacgcacag gcatatactt cttttgcgcc gttttctttt aatacatttg
    57061 ctgctcgtgc aagcgttgct cctgtgttca agatatcatc taccatgata catgtctttc
    57121 cttgaacatc accgatcaca taaccaccct cagttgaagc atcatctgca tgatctacga
    57181 tggctaatgt gctgttcaaa tattctgaaa gactacgtgc acgctgaaca ccgctgtttt
    57241 ttggcgaaac aactacgatg tcatctcccg tcagacctaa ttgacggtaa taatgagcaa
    57301 acaacggcat cgtaaataaa ttatctacag gaatatcaaa gaatccttgt acttgaaccg
    57361 tgtgcagatc taaagtcagt actcgagttg cccctgcttc ttcgatcaag ttagcgatca
    57421 atttcgcagt gatcggttca tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt
    57481 aaggcaatac gacattgatc gttttcgcac ttgctcgctt cattgcatcg atcatgatca
    57541 gtagttccat atagtaatca ttgacaggtg cattcgttga ttgaacgata tacacatgat
    57601 cccctcgaat actttcttcg atattgatgg aaatctcgcc atcactaaat tgcttcacga
    57661 cgcttttacc taattctgtt ccgaacactt tcgcgatttt ttcagctaat ggacggttgc
    57721 cattcaaact aaaaatcttc aacgtgtcat cctgatactt attactcatg tagtcctccc
    57781 caaaacttct ctattcttcg atagtttaac atatttttcc aagattttct gttaatttca
    57841 gcaaattctt aaggaagtga aactgttccg ttactccaac tggcaggaat gactttatga
    57901 taatcgcccc agttgtcgtg tactttgtaa taacgttctc ctgtttcagt ttcaaaataa
    57961 gcgtacgctg tcacccaatg attgccatat gtactgccaa gtactttcaa aataccaatc
    58021 atcacaggtt tgccttcacg tatacgtttt gtagctcgct gccatgaacc tagaagagtt
    58081 gctcgtgcac gctcatgatt gccattcttc tttaaaaaac tagaaatccc tgtactaacc
    58141 tgaaaaggaa tcgtaggaag tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa
    58201 accaacgaat cagccgtatt tttcttgcga atctcatttg gaagcatcca ccccttacga
    58261 tagtcttgat aataggcaag gagaactgct gccgcgtaag taccacaaag atagcctgag
    58321 ggggtagccc atttcttata cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt
    58381 gcgagttcct ttcctgacct tttttcttcg atcaaaacgg gaatatcttc ttttctgttg
    58441 atccatctag ataactcgat tggctcttca ttgatcagct tccatttttt acaagaaaga
    58501 ccctcttgat aagtatattt tgctggagaa tattctaccg gatgtcctga ttgatcgata
    58561 atcacataac tttgatcttc aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac
    58621 tgcagctgct gagtgctggc taatttttta atttttttat ctactttgaa atataaaggt
    58681 ttatccacta cttgattcag ttgggatcgc ctcctttttt tcattataag tgaaggattg
    58741 aaaaaaacaa atcagtttga ttgttcgaat tttcaatttt ttatgttcta tttgttaatt
    58801 ccttcatttt gtaagataat gggcacacga aacaaaaaag gagcgatcga tgaatgaaca
    58861 aagaacgatt gaaacaagat ttctatgaag cagtcaatga agaatggcaa aaaacagcaa
    58921 aaatccctgc agataaacca gctacaggcg gtttccaaga tttagttgac gggatcgacc
    58981 aacttttgat gggagaaaca gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa
    59041 aaatgaaaca tttccttgca tattatcaac tggcaaacga ttatgaccga agaaatgagt
    59101 tgcatgctca accgcttcaa cctataatcg aaaaagttga atcattgcag tctttcgacg
    59161 aattgaataa gcaatttcca gaatggctgt tggatacatt accattgcca tttaatctgg
    59221 atgtagatgc agatatgaag aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt
    59281 tattccttcc agataagacg tattatgcat cagaccatcc caacggtgca caactaatag
    59341 gcgttttctt tgatatggct gttcagttat tagagcttgc cggcaaagaa aaaagtcagg
    59401 cagaagcaat cacggaacaa gcagtgcaat ttgataaatt gattgctcct catgtaaaaa
    59461 gtgcagaaga aaacgcagat tacagcaaaa tgtataatcc gcaatctttt gatacattta
    59521 ttaaatacac agataaactg gacttgaaaa aacttgtcac gggtttgatt gggacaactc
    59581 cagataaagt gatcgtaact gatccagtgt acttcgatca tttgaatgac atcctgacag
    59641 aagctcattt tccgttattc aaaagctgga tgatcattaa aacagtacgt tctcttagtg
    59701 gttatctatc agaagaattc cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa
    59761 cagacgaagc aatgcctcag aaaaaagcag cgtattacct tgcctctgga caattcgatc
    59821 aagtagttgg cgattactac ggaaaaaaat attttggcga agctgctaaa aaagacgtag
    59881 aacaaatggt gaaaaaaatg atcgccgttt ataaaaaacg tctagaagaa aatgactggc
    59941 ttggggatgc aacaaaagaa aaagccgtca taaaattaaa taacttaggt atccaagtag
    60001 gctaccccga taagatccca gcattattcg accagttcaa aacagtacct gcagatcagg
    60061 gtggtacttt gctttcaaat actcttgttt tcagcaaact cacattaaaa gatcgtttca
    60121 gcaaatggaa caaaccagtg gatcgttcag aatgggaaat gagtgctgac acggtcaatg
    60181 cttattatca tccatttcgg aatgtgatcg tctttccggc agcgatcctt caagcaccat
    60241 tttacagtct agaacaatca agctctgcta attatggtgg aatcggagct gttatcgctc
    60301 atgagatttc ccatgcattt gataataacg gcgctttatt tgacgaatat ggcaacttga
    60361 acaactggtg gacagaagaa gatcttacac aatttcaaaa caaagcacaa gcaatgatcg
    60421 aagaattcga tggtctgcct tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg
    60481 aaaatattgc tgatgcaggc ggtctaagct gtgcattgga agcagcaaaa acggaatcag
    60541 atctttctat cgaggaattc tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa
    60601 aagaatacca acaactttta ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa
    60661 acgtgcaacc aaaaaacctt gacgaattct atgaaacatt tggtatcacg gaacaagacg
    60721 ctatgtatct agcgccagaa aaaagagtgc gaatctggta agaggttgtg ccagaagtgg
    60781 tcagcttcaa gaaataagaa ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt
    60841 cggcttattt ttcgaagaag ttacttctgg aataccatgt attagaggtt gtgaaaaagc
    60901 tgcttagttt caagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa
    60961 atttgactta ctaccgagaa actggctttt gaacaccgtt tatcgagagg ttgtgaaatc
    61021 agcgtcctga cctgagtatt agagaaaaaa acggaaaaat agttcctcat attttgccgt
    61081 ttgttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa
    61141 aagctgtcct gcatcaagta ataagaacag ccaatcaaaa gcagcaagga gaacctcatc
    61201 tataaaaaga tagaaggaag tgagacatct attggtctca tttccttcta tttttacttt
    61261 cctcagtcaa ttgttttaca tcataaaagg agaaattcca cttatttttt tcgctgtttc
    61321 atgacataaa caactacacc gattaacaaa attcctccag ctaatgctag caacgggtta
    61381 ttaaattctc ccgtttttgg gagtccttga gtgccatttt tttcactttc ttttgctgtc
    61441 ctatccggat gagaaggttt tccatttggt tttccatttg gtgattcatt tcctggattt
    61501 tctctttctg gtttgtcatt tcccgggggc acatcggcag tttctcgcac agtgatcgct
    61561 ttttgctggg taacagattc tgtatgagca gaccattttt ccccatcaaa tatttccgaa
    61621 cgataagtga cttctagcgt atattctcct tttgaaggtg ctgaaaaaat agcggtatga
    61681 ttagaaaatt gagcacttga ctgtgtttca acgatttgga tcttttctgg gaaataacgc
    61741 atatcttcaa agacaggcgt tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa
    61801 ggcttcagtt caatgatatt tccttctgca ttctccgcca caccatttgc ttcttgtata
    61861 ataatcggat tattttgttc atttggtttt gtctgatttg gttcttgtac gattgcatac
    61921 tctggatatt ccgaagacgg tgaggtttct ccgtcaaaaa tagcacctac agataatgga
    61981 agaccatcca ctctttcctt ttctgtttga cgattccccg gtttaatctg catcagtcca
    62041 tgaacatgga tacttccatt ttcatagcgc gtaacaggct gctgaccttc tttcgaacat
    62101 gtatttagag actcgatcca atcttttgat atggtatgtc caagagtatt ttctgattgt
    62161 ttctctcgtt cattccaata gtagttcaac gagtggtaga tttgatcttc gttttgattc
    62221 aatgggcgga tctgctctct catctcaaga ttctctgttc ggaaagataa gataccagaa
    62281 gcatggtagt ctgtgtttcc tgctgaagag gtataaagag ccacattata tgaaccgtta
    62341 ttaaaacttg tactgctatt gacgataata tctgttccgc tattggaatc gattcctttc
    62401 gcaagatttt cgaaagacaa actattgatc aattcatgag ggcccgttaa agaagaaccg
    62461 cccattttga atccattacc gttaccttct ccctcaattc ctggtaccca gccgtttcga
    62521 taagcaactg agtttttgat gattactttt ccgatcgaac ctgtttcatt tttagcaaaa
    62581 aggtcccaac cgtcatctgc attatgatac gcgatacaac cgtcaaatac atttccttct
    62641 cctattgtca gtttggccgc aaatccatcg gcatcttcaa atcctggatc ggcattttca
    62701 aaagatgtac agttcttgac taagttatgc gcgggccatg cttcgaaagg atcatttgag
    62761 ctaccgctga tttggattcc tgtatttcca ttccgataag catgaatctc ttcgatcaaa
    62821 ttatgatttc cagaaatctg taatcctttt tgcatagctg cactatttgt aatgtcaaac
    62881 cctcgtaaac cccagtagtg actgaacagt gtcatcccat ttccagttcc tttaaaatca
    62941 agtacaggac gcttgttttc tggatttttc tctgcaatca actgaatcgg gttttctctt
    63001 gtcccgttaa cgccttttgg aatcgtcaat cctctttcga aggaataagt tccaggcgcc
    63061 atgacgattg tctgcccagc atatgcgtat ctcaatgctt gtgtcagaga taatggattt
    63121 tgtctgcttc cgtttcctgc atctgaccct tctggtgtta cataaactgt cgaatattta
    63181 ggtttacggt agtccactgt atgaagaatc tcttttgttt cataactagt catctctacg
    63241 tattcttctg gcggatagtt tttatctggc gtaaaactga aagtaaattc gttcgttcct
    63301 tccatcagtt ttgtctgata atcaaattcc cgattcgcag tgatagccaa gttttttgcg
    63361 ttcttaagca cctctcctgt tgctttattt ttaattgtca ataatccgtc agcatttgct
    63421 ctaaaggaca tagtatgatc ttggtttcct gaatgattac tagaggtcac agtgtaaatc
    63481 ggatcaatca agcgagtagg tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa
    63541 gcaacttcga ttccttctac cttgatcgtc atattccttg ctgcagcaaa tcctgcataa
    63601 ataaccgatt catctgaagc gtataatttt tcccagtcat acatgatgtc agaagccatt
    63661 tcttctcctg tttcaggatc gtaataatat gcctctaaac cagtattcgt ttttttcatc
    63721 tctacgtcca gtttagtaat cgagttcgtg gccggaaaca gattcccatg accgtttccg
    63781 aatatattat aagaacctgt ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt
    63841 gtttccactg agacactccc aggagctggc gcagcttgcg gatcttcaga tgatattcct
    63901 gtgattgccc gtgtccccaa tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc
    63961 acttcttgtc tatccgagtc ccagacatat tcgatccgac tgcctagtat ggcaaatgaa
    64021 tttgaataaa atgcctgccc aaacaaatga ttttttggta ctgcgtctct taccattaaa
    64081 gcaaatcctt cttgggcatt cgtataggtc caagattcta tttcgatcgt cgcccgcatc
    64141 ctaaagttga tgtctttggg gattgcttga taataatagg tcattccatc tgatccgctt
    64201 gactggaatt ttccgccgtt attcgtggaa gagagccgca cgccgtcttc taatggttca
    64261 atggcatacc tactagcact tgtgctttct ccgaaaacaa cccctttcca ctcttcattt
    64321 gcttcttcag attgcttttt tgtcttttca ttttctgatt ctttcatcat aggatcattt
    64381 ccttcttccg tatccatatc ttcactagtt cttggtattt cctccattgt tgacatccct
    64441 tcaatgttca cgtgtgcatt ttcttcgttc acagactgtt gttcgttagc agcaacttca
    64501 acgacagaaa ttaaaaccgg ggtactgagc ataaggagat tcatcattag cgcactgtat
    64561 tttatacgtt tttttaacaa gtgtattcct cccgtaacaa attagaaagc gtttacttaa
    64621 agtattacct aatttatttt tactgtcaat aaaaaacaaa attataataa gtgtatttta
    64681 taaaaagaaa aaatataact taagttgttg ataataaaga gatttattaa cgtaaaaaga
    64741 ataagttttt ttaaaataac gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc
    64801 tcttctttta ttattttgtg ctttttattt tatcaaatca ctttgttttt ttataaaatt
    64861 tctgcgccta gtgtggactc aaaatgtctc aatgcccatt catgtccaac gggatcgaaa
    64921 cttgccacgg catctttgaa aatatggagt ttgtatccta gattatacgc atcgactgct
    64981 gtatgcaaca cacagatatc tgtacatacg ccggtcaaat aaatatctgt gatctggcgt
    65041 tctcgcaaac ggatgtctag atctgttcca ctaaaagcgg aataatgccg tttgtctatc
    65101 caataaacat tttcctcttg ctcatagtct tggtataaac tttttaaaga gccgtacaat
    65161 tcccgtccac ccgttcctat cacattatgc ggaggaaata agcggttctc cggatgaaag
    65221 gaatcttttg gatcatgcgc atcaatggca aaaacgacaa aatccttttg atcaataaac
    65281 ttctttgtat gagcagtcag ctttttttca attacttgtc ctgctgtccc agtagtcagc
    65341 tttccatcct ctgcaacaaa atcatatgtg tagtcaatcg agatcaatgc gttcatctta
    65401 gtcctcctta tacgagatgt ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg
    65461 cgtcttcgat aaattcgtca aagctttgtg tcgccgagtg atctgctgtg tcgctcattg
    65521 cacgtacgat caaaaatggg atattgaact gacgagctgt ttgtccaaca gcggctcctt
    65581 ccatttcgca agctaatgct tcagggaaat tcgttaagat ttctttgatt ttatctggcg
    65641 agtcgacaaa tgtatcacct gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt
    65701 ttgctgcttt aaccatttca ctgcgcaaat atgtgcttgc ttcataatat agaggcattc
    65761 ctggtaattg tcctgggttg tagccaaatc ctgttgcatc tgcatcaaaa taagctactt
    65821 tgtctgatat aacgatgtca cctacttgta agccttcacc gattccgcca gctgaacctg
    65881 tattgatcac catgttcacg ccgtattgtt ggatcaacag acttgtggta atagatgcta
    65941 agacttttcc tataccggaa cgtacgacga tcacttcgtg gttacctaat gaacctgaaa
    66001 taaataaagc gcctgcgcgt tcccatgata atggttcgct taggttctct ctcaaaattt
    66061 ttacttcttc ttccattgcg ccgataatac cgattttcat ctttttaatt ccttctttct
    66121 atataaatgc gattgctaaa aaaaccacac ataacattag gataacaata ataagagatt
    66181 tcatcaaaaa agagttccat ttggtcgtct tttcccgttc gctgatcctt gttttcgtga
    66241 ttggtttatt ctttttgctt tctttacgat aaaagctggc aatctttttt tcttcttgct
    66301 gataagctgt ttctgctttt cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc
    66361 gcttgcgaag ttcgcttcgc gtaataagcg gtcctttggc cataagccga tccctctact
    66421 ttcctttggt caatagttcc cagtattgaa tcgcataaat cgtctttgca tcacaaatca
    66481 actgatcttt catcgcttgt tgcgcctctt caagagttag atgatacaac tccagtactt
    66541 cgtcttcatc ttgtgctaaa ggattctcga ccttctctac cccttgtgca tgataaatat
    66601 gaaggacttc atttgcaaaa cctggtgaaa gatacatcga agtaagatgg ctcagcgact
    66661 tcgcacgata gccagtttct tcttctaatt ctctagctgc tgtcatttcg ggattttgtc
    66721 cttctcctgg atcgattttt ccagctggaa tctccaaaat cactttttct aaaggttttc
    66781 gaaattgttt gacaagaagc agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc
    66841 caggatgaaa taccagttct ctcttcgaag ttcctccatc tggcaaacga acttcgtcta
    66901 cagcaacatc aataattttt ccgctataga tttctttgcg actgattgtt ttttcttcaa
    66961 attgctcatt gttcagcata tcttctcctg ctttctttgt aatcataact gctttttttt
    67021 catttttcaa tttttctcaa aaactcctta ttagtttacc atagataaac cttagatttt
    67081 ctctaaatat agaaaatcct tctttagtcc gatactcttt atagtagtcc gtatgctaaa
    67141 ataagtatgt aatcgaataa cgaaaagaat tcaatactca acgataaatg acatggaggg
    67201 tttattatga taaaacgaaa ttggccgtgg cttctagcat tggtcttgct atttctcttt
    67261 gtccgaaaca atagtttttc ttttgttcta ggacttttat tgataggtgt agttttagtt
    67321 ttgtggggac tctttggttc gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg
    67381 actgacgaac ttgaaactca ctatgaaaaa agcggtatga cagcgaatga aatttcattt
    67441 tttcgacaaa caatgaatca aacaaaaaat gagatcaatc aattgcaaat gaatatgcag
    67501 cagacagcca aacttaaagc aatcgatctc cgccatgatc cagtcaaagc agcgaaagct
    67561 ttattcaaag aattggtgaa agaaccaaac cgactgcatg aagcaagtca gtttctttat
    67621 acgcatctgc cgaatctagt tgatttgaca aataagtata atgagatcaa tgaccatgag
    67681 atcaaaaaca aacagaccta tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg
    67741 tcagctttaa tcgcacaaga ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac
    67801 gtagagatat ctgttgcgaa acagagctta aagcgtgata ataaatatga accagaacaa
    67861 aaggattaac tcttttgttc ataaaagaag actcggaaca ttcagatgat gtctggctgt
    67921 ttcgagtact ttttctaaag tagagacatt catgtaagaa tcgagaacag attcaacaag
    67981 gaggaatttt ttatggatca taaaccgact gaaacaaaag atgttacacc agttaacgat
    68041 acacttgaag atttattgaa caacccgttt tcaactccaa cagatacgct gaccacttca
    68101 caacaagcgg agattgatca gctccaagag caacagacag ctgctcgttt aattgacaaa
    68161 ctaccggcgg aacgccaaga acaagctaaa cagctagcag caaaaatcga tgctaatgat
    68221 gcacagtctg tcatcagcta cggatcggct gcccaagcaa aattaagtga attctcacaa
    68281 tcgatgttga atcatgtgca agcacaagat attggtcctg taggagattc cttaactgaa
    68341 ctgatgtatc gtctccaaga agccaatcct gacgaactgc gtgccggaga agggaacatc
    68401 ttccagcgtg tcttcgggaa ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa
    68461 aagattggtg cacaaattga caagatttca gtgaaattag ataaagaaaa agacggtctg
    68521 ctaaaagata atctgatgtt agaacagctt taccagaaaa acaaagacta ctttgatgca
    68581 ctgaatattt atatcgctgc tggagaattg aaaatggaag aacttcaaac aacgatcatt
    68641 ccagaagcga tgaaaagagc agaagaaact ggcgatcaga tggatgttca gattgccaat
    68701 gattacacgc aattcctaga tcgtctggat aaacgtacgc atgatcttcg cttagctaga
    68761 cagatcacga tccagcaagc accacaaatc cgtttgatcc aaaacacaaa tcaggccttg
    68821 gctgaaaaga tccaagcatc tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg
    68881 atcgcattga ccttgcttcg tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa
    68941 acaacaaacg acttattgaa gaaaaattca gaaatgctga aaatctcagc catcgaaaca
    69001 gcgaaagaaa atgaacgtgg aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat
    69061 ttgatcgaaa caatccaaga gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt
    69121 catgcagaag tagagcttgg acacatggaa gaagatctga aacaaaaact gttggattta
    69181 acccaataga tcacctttcg cttgttacta aaacaaacgc ccaacaacag tttattacaa
    69241 ctgttgatgg gcgtttttct tatctttctt ctaacttctc cattggagtc tatttctcat
    69301 tcatcttgct gtgtccatag ccatagccaa aataaatgat cagtccaata accattacga
    69361 taccgaacac gatccatgtc acagtttgca gacgaagcat caatacaata caagtcaaga
    69421 tggagacgat tggcaatagc ggaacgaatg gcactttgaa ttctccagct tttggtttgc
    69481 caaacatttt tctcaacttc agtaagccta gactaacaag catcaaatag gcgagcgcca
    69541 tgatattcgt tagttccgct aatacattca atgggaaaaa tccggcaaag aatacagctg
    69601 ccacaccagc ggcataagtc gcttttttcg gtgtacgatg cttttgatcg atttctgtca
    69661 taaacttagg aagtaagcca tccttgctga cagcaaacag taaacgagca agtgaataca
    69721 tcatcgagat cgttaccgtc agtagcgtta aaattgcccc tacagcgatc accgcgccca
    69781 ctgttccatg tcctacatac ctcattgcaa aagccactgg gtcattgact cctagttcag
    69841 tatacggaac gattcctgtc aagatcagcg tcacgatgat gtaaaggaca gtagcaatca
    69901 gtatcgaacc aatgattcct cttggcacat ctttttgcgg gtttttgact tcctcggctg
    69961 ccattgcaac ggcatcaaat cccaagaaag caaaaaacac aagagctgca ccatctagca
    70021 caccggaaaa accaaaaggc atgaatggct gccagttatc aggtttaacg aaaaatattc
    70081 ctacaatgat aaacaacgcg atgataccaa atttgacata taccatggca ttattcaaac
    70141 gtaatgcttt cttggcttca agcgacacga tgtaagtgac gaatatcact acgagcaccg
    70201 caatcaagtc aatgtatgta ccattttccg gattgtaccc gccagttaat gcttgtggaa
    70261 gttcggcccc taaacttttc aaaaaacctt gcatatagcc agaccatccg gaagcaacag
    70321 aggaaaccgc tagtaaaaat tccccgatca acaaccaccc tgtcagccag gcagcaaatt
    70381 caccaaatac aacatacaga taggcatatg gcccaccaat cactggcact cgcgaagcaa
    70441 attctgcgaa acttagtcca gacaaaatga caacgattgc agctaagaca aatgaaagtg
    70501 acagtgctgg accagcattt tgattggccg caacccctgt caccacaaat attcccgtac
    70561 cgatgatcgc accaattcca agcatgatca aatcagacgt ttttagttct tttttcatct
    70621 cactcgtatg attgagattg atctctttct tacgaaacaa atccattgaa gttcctcccc
    70681 attttaggtt ggaaaacagc gattaaactg ttttcatata ccctaaaagg ataccaccta
    70741 aaatgactaa aaggcaacca acaataacat aaatgagctc ttttttcgtt tttctttcgc
    70801 caaggatgaa aatcccacct aaagtagaga taatgatccc catttgtgaa agtgagaagc
    70861 caacagctaa accaagtgat ttgactgtta gaagcatgca gatgtttcct aagccccata
    70921 ataatccaca gatcatgttt ttccacacaa actgatcgac tttaacttta cggaaagcaa
    70981 agaagcttgc gcctaagatc attccgatac tttgaggtaa gataattgac atcgcatcca
    71041 aattcgccca gttgacgatg atggtatata caccataacc aatcgtagag aagatcaatg
    71101 ctctaaaacc cttaccaaaa tcaagcattt tattatctgt atctattttt ccttcgtcat
    71161 cttgtcgggc agtcaaatac gcaccgctta caagaagagc taaagcaata ataccgtata
    71221 cataatcttt cgtttgtgtc cattcatgga agaaaacggc tcccgcaatc gtattcaaaa
    71281 ttaattgaaa accagtagac aatggtagcc ctacagaaac acccatgtac ttcattccat
    71341 ggaactgtcc attttgtcca acactccaag ctaagccgga taaaaatccg atcaagaaaa
    71401 tccaaggggt gattacagga ctaacaacga aaaagacaac taaagaaaac agaaatgcac
    71461 cgatcgtcat tcctagtgtt tgttgattgg catcgccacc aattttacca cttactaaac
    71521 caatactacc ccatgccaac atagggacta atgctattaa aatttccata accaatctcc
    71581 ttttatttca catgataaga aacttatcag cgaaaacgtt aacaacacaa gcactttttt
    71641 tcgtttctaa cgattttcta acgtttttca ttataaaaat ttaagattgg gaaaaataaa
    71701 gtcattgttg tcccttttcc ttcagttgat tcagccgtca aatggatacc taatttttcg
    71761 gccagatttt ttgctaaata aagtcctaat cctgttgaat gtgttttgct aagtcgacca
    71821 tttctcccag taaatccctt atcaaagatc cgtttcaagt cttccgctgg gataccgatc
    71881 cctgaatctt taactgaaag gctgactcct tgcgcttcct tttctatgct cacaatgatg
    71941 tttccgtgat ccggcgtata tttgatggca ttactaagca attggttgaa gataaaagcg
    72001 atccatttag catcggtcaa aacagtatga tcctcaccaa cgatctcgta gcgaatattt
    72061 ttttggataa aataatttgc ctgactgcgt atcacaggct gaatgattcc ttttagtcca
    72121 tattcttgga tgaggtagtc ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt
    72181 tctacgtatt catcgatttt tgataattca ttttctagta atgtatactt ttgatcgtca
    72241 atatcgaact cgatcgaacg aactagcaat ttagaagcgg aaagtggcac tttgatttca
    72301 tggacccatg agtcaatata atctttttgg tcttgttgat tactgattgc tgattgcatt
    72361 acttcttggt gttcacggat cagctgattg atatattctt ctaccagttt ttcttcttct
    72421 gtcctcccac cactcaaata attttgcaaa ggggaagttt tttgtatgtc ggctaatttt
    72481 ccccaccatc ttctcttgct caagtaacca cccagcagat aaaaaatcag aaagacgccc
    72541 tcaatcaaag ctaaataagc aattgtgctc aaatcaactt tgatgtttgg cgccagccac
    72601 atcacaaaga tcgtcaatgc aataaaaaac agccatccca agatcaatgt ccactgatct
    72661 ttcaaatatt taaaaaaatt catcttaacc gctcatcctt tcagggaacg atatatccct
    72721 gtcctacttt tgtttcgata tatccttgga tacctgcctg ttcgattttt cggcgtaacc
    72781 gattgatgtt gactgtcaat gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc
    72841 gcagcaattt ttcccgactt aagatctttc cattgtgctt catcaaaata aataatagac
    72901 gatattcatt tttgctcaaa tcaatgatct ctccgttgat ttccatactt ccgttgtcaa
    72961 cattcaacgt aatgccattg tggctcatca tttcactaga taattctgtg tagttgtaag
    73021 aacggcgaag taatgcattg atttttgcaa tcagtacatc gatttggaaa tgttttgtca
    73081 caaaatcatc tgcccccatg ttcatagcca tgatcatatc catattcgta ttcctgctgg
    73141 agataaaaat gatcggtact ttcgatactt cacgtatttt ttgacaccaa taatagccat
    73201 ccaaaacggg aagattaata tctagtaata caagctgtgg ttcttctctt tcaaagtctg
    73261 agaacacttg attgaaatcg gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct
    73321 ccatgatcaa ttgtcgaatg atctcttcgt cttcgactac catgattttt gccataaaaa
    73381 atccctccat ctttcttctt gctactacaa tatcaaagaa gcccttgtga aacaagttgg
    73441 cttacctgga aaatgtcatt ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat
    73501 cgcgtttgtc tcttccaagc agcttaaatt tattatgtta ttcttaataa ttggtctatt
    73561 atctgttatt tttctttcgt tgtttttgtc ttttaaattt tcgataacac caataaccga
    73621 aaagcgttag cactagcaat atacctagaa ggagtataag taatcgataa agatggtatt
    73681 tttttgtctg ttctatcttt gaagagactt cttctgtaaa gggaactcgt cttcctgtca
    73741 ctagtaatcg gtgagtgttc acggtgtaag gtgtacaagt gataagtgtg actagatcct
    73801 gcttttctct aattgctaat gtatttgttt ttgttggaag gacaacaatt ttctcaacga
    73861 cttcataagc gagcatccga ccatacactt caagatagaa tcggtcatct tgctccattt
    73921 cttcaagatc cgtaaagagt tttttctcag caataccgct atgggcggta atcacggaat
    73981 gtgtactctc tcctccagtt ggaaaagagg tgccttgcag gactgtcgct cctctatcta
    74041 acaaaagatc attcgtttca tcaaataaag gcaagctaac attgattttc ggaatataga
    74101 tggctccgat catatgttgt tcgtaatatt cttttcctgg attttggaca tttctaaccg
    74161 cttgctcaaa aggatctttg acttgtccca ttcctgggat tactgatgta tgagcaagcg
    74221 tctgattttt cttttcatgc actgctaatt gttgctcatg tttttcttct ttatcgcgtt
    74281 caagctgctt ttgataattc tcgatccttc tttgatccaa ataattgctg agagcatctg
    74341 ctaaaaatgg atatgtaaaa actgcagctc cggcaagaaa catcactgcc ataaataatt
    74401 gtaataaaag actgatttgg gtttgaggtc tattacctat tttctttttc attttcttca
    74461 ccttcttatt taaaaaaact gcagcaacct ttataaaacc gattgctgca gcttattttt
    74521 gttgcttata cttcagactt cattttagat ttacggtacc agctgtacgc tccaatcatc
    74581 aaacttattc cgattagtaa gaatgccaag agcccgttcc caccagtagc aggaagtgac
    74641 ccgcgtttca tattcggtac tctttctggc cctggatttt ctactcctac gatctgaatt
    74701 tcttcattat agcttccata agagatgata aattcagtaa aggctgcctc acctgttgga
    74761 agtacataac cttctggcgc catggtctct ttcatttgat aggttccata atctaaccct
    74821 tgaacctcaa agtatccatt tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc
    74881 cactcaattc tatctgctcc tgattcataa acagctaaag gcgactcccc tttataaaat
    74941 attgcgtatt cagaacggtc ttcattccac aattcgaatc ttgcatcttt aagcaattca
    75001 ctgcttgatg catcatattt ttcaaacttt cttccacctg ttgtgacttt ctctggcggc
    75061 tctactcctt cttcataatc aaattcatca tttcgtccga tttcaataac cgctgtgttg
    75121 ttatggaaat catccgcttc tagttctgtg gaaaccttca aattatacgt gatcgttaaa
    75181 tctcctccac gtgcatctgc taatctacct aaagtatcta ctttggctac tccattttct
    75241 tctgtcaaaa tcgtcacgac aaacccgttg cttactactt ctactatata atcttgtcct
    75301 tttgttaaaa tcgtctcgcc ggctcgcact tctatttcct gatcataata agttagacca
    75361 actgtaggcg tatctgtgat tttgtaattt ttgataacag cgcttccgtt ttcaaggaca
    75421 gaatcgatga aataaggaat aggtgctgtg atcgtgtaag aagccgtttt tcctctttct
    75481 agatcaatat aagaaatcgt ttcttgttct ccagcttcat taataatcgt tacttgtcta
    75541 aggtcgcttt cctctacatt catctgttta tctgcttctc tgatttcgtt tttcggatac
    75601 aaatgcacat ctgtattgta tgtgtctttc catgtagaac catcccacac gccatccacc
    75661 atatcaggca tcatcactgg catcataaca accattggag acgcgattct ggaaatatga
    75721 gctggcgaat aagtttctaa gaaaagatag actttatctc tagaagaagg tgcttcttcc
    75781 gtcacttgga cggtagagaa taccgcttct ccagcttcat tcgttgtttg tttgtcaata
    75841 cttgtcagtc gatattttaa aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc
    75901 gcttcggcag aattaagacc gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa
    75961 tcgtaatata cttccgttac gtcaaacaaa tcaaaatcga ctcctggaat attttcttca
    76021 ccaaaatccg tagaaaccaa tccgctattc ggtcgttctt ccggaacaga tgagaaacct
    76081 tttttgtgta atgtaatcgt cacttcactt ggtttttgtg cgacttcttc ggctttgact
    76141 agttttccgt tcccgaaaat ccctattccc gcagtaacga gtaacagtac actcattccc
    76201 gtgacaatca tttttttatt catttttttc tccccgttct ttttttatta ataaaacagc
    76261 acctaacaat aaaagaattc ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg
    76321 gaatacggac cattttcctg attgacctgg attgcttgga ccactcggct ctttcggttt
    76381 gtccgttgtt tcttttacgg tctcgttata aacacgtggt gttgcggatt cataggcaga
    76441 gactggaact ttcccggatt ctaattcagc catctcctgt ccgttaacta ctacatattg
    76501 tggttggcct tttgcatcca cccaaaattc agggatgatg acctcgattc tcttacttgc
    76561 ttcatccatc tcgtaacctt ccacaccttt taattcttca aaataatagg tgccagaagg
    76621 caagaaacgt tgtcctgtcg taacaaggcc ctctttatcc gaaatgaatt tgcttacatt
    76681 tttgtcattc aaaggatcat tgtctgctgg tttgatccat tgatttttca agtcattagc
    76741 aggagccata tctaaataat atttcccccc ttctatcatc tgatatagag caaaaacagc
    76801 accttctaat ggttttcctt tttcagttgt tcctctttga cgtccatact tgaagaagta
    76861 tggatctctt agataaccga catttttagg atagatatga atctcttgca gttcctcggt
    76921 tgattctgtc gggtgataaa ttggcaaaat agcagcaatt gggatagctg tctgatcgat
    76981 atcaacatcc aatccaactt ctggatcaat cgattcttcg aaaatcaaat aaactgcatc
    77041 ccgatcttgg tttttcttag gtgctttgat acgtgcaatc ccgtctccta atccgccaac
    77101 cgtatctttc ccagttgtta ccgaagtccc tatttggaca agcctttctt ctgtgattag
    77161 ctgacggata ttgtttctgt tcgtttcagc gatttgctgg acgaattctt taggagtcat
    77221 gttttcagca gctttttttt catgataata atcggtcatg tcgtaaatgg caaatgtcgc
    77281 tccatttagt ggcaccgtct gtgaaatgat atctgctgtt tcccctgctt cctcagagat
    77341 agccaagcca tcattttcat ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat
    77401 ccgtttatgc aacacgaatt ccacgacatc ttcccctgat tcttctgccg acatcgcatg
    77461 tggaagaagg actgctgcaa gcggtagtaa aacaagtaat tgaagcatca aacacaacag
    77521 ctttttcatt accttgctcc ctccttttta gattgtctga caaacaaacc ataggctgct
    77581 cctgcaagcg ccatgaagaa tgcagcaagc aggatataga ataatcgtcc ggatcctcct
    77641 gtagcaggca acggattttc aggatcgttc ccgacactaa gctgtaatct gattcgattt
    77701 gtctccaaaa gttcatattc taactcttgc tgtagatcag gcgtctctgc ttcttcgttt
    77761 ggataatacg aaatctcaac ttttagtgta cccgcttctt ttcctggaac tacccgatca
    77821 ttttctatgt caggttcttc tcgataacta atttctaaaa taaagtaacc tggaagtttt
    77881 ctatagctgt caggtgactt cacttccttg atccgataga ccccttccaa caagtctgaa
    77941 gcattgaata gggaagaatc gtttggatct ggtgccaagc ctccctcgat gatttcatac
    78001 tctcctgcac tattttgttt ctcaattgaa aattctgcgc cttcaagacg tcggctattc
    78061 atactgtcaa ttttcaaaag ttccaaatcg attggcgcta gttcatcttc taaggttact
    78121 tgtagtacac catcgatgat ttcatagcct tccggcaagg gagcagtttc gtcttcgatg
    78181 accgtatctt caatgataaa cttaccttct tcattcagtg caaactggaa cacttgatca
    78241 gatagccgat acccatttgg tgcgacagat tccgagacct catattcacc aatagacaga
    78301 tgcagaggtt ggtcgtaatt taaatcgaca tacttttcta ctcctacggc acgagaatag
    78361 aagtatccga tcccaggcaa acgtttcgat tcttctggtt ctaacggatt accagtgtat
    78421 gctcgataca gcgggaagga agaatccccc actttcctga tatcgaaacc tgcaccatct
    78481 aatgtatggc cttcatggtc taattttcta actcggatct cccgataatc aaacgtattg
    78541 taagcagtga atgctaccca taaacgatcc tcttcatctg ttgtatacgt gagatattgc
    78601 caattttctt cacctgtttg cttgagttgg atagtcccta tagcattatc gtaaagtcgc
    78661 aagatccatg tgtcattttc atcaggttct ttgaaacctt ctgggttctg gctctcaatg
    78721 attttgtatt ctgcatagtt ggtagtttct tcactatcct tataaacaaa tgaatctggc
    78781 tctccgattg gatgaataac tttctcacca tccacgatta catatttccc gtcttcatct
    78841 actgaataga acgtgagtct ccctttctct tcctctactt cgttcacacc agaaagccct
    78901 ttcgctactg gatatccgat ttccagtccg ttaccatctg tttcataaag ttcaaactct
    78961 gcgccattga ttggcatatt actgccttca attagtttat tgatattcat gtggattggc
    79021 ttgaattcat ttcgcatttc cagtttgaca tacaactcat catactctgt gccttctatg
    79081 ttaggctctt gtacaacaga aagcttgtga tattctcctt cataatagga attcggatct
    79141 ttaccttccg gtccgccgac tctcgaacca gatgtatatt catctacaag ctcgtagtga
    79201 cctaacatct catcttcgtt ggctgcatat tttttgattt ggaattgata cgtctcatct
    79261 actaactgat aacgtggtgg tccagcgatc tctctgatcc aaaatatgtc gctgactgct
    79321 ccagtttcat ctcctaaaat cggcatcttc gtttcaaaga tcgctattcc gtccgtggta
    79381 gttttacttg tttcgattgg ttcggcttcc ccactctctg gattttggtc atataatgca
    79441 aattcgactc cagccaacgg ctcgccattt tgacccttct tgctgacttg gaaattacgg
    79501 cctttatgtt cgtaacgaat ggaagaagat gggaaataca tccgtccagt agtgatatca
    79561 ttctcataat cctccaggtt ctgaatatag gccatattgt tcactgtgca aaaatttccg
    79621 tcttgagctc ccgcatcaag ttttacttgg tacttgatcc tgaccatttc cccttcacct
    79681 aaagaaatcg gagaaaattt ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc
    79741 gccactactt ctggtggggc ttgtccatga cgttcttcat cccatatttc tggctcttgg
    79801 tacttcatgc cgttttctcc tggatctaga tggtaaaact gaatatctgc cgatctgcca
    79861 gctccaaatg gtgagacatt aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt
    79921 ctcttgaagg tagaagagat atcctccaag gctgtaacaa tgtcattctt gttgttcgca
    79981 ttgtaatatc gcggtgttac gccatcttct tctaaatcag caatattttt caatacattt
    80041 cgtccaatag catctagtcg ttgtctcccg ctaacgtttc catcgattcc taaaccaatg
    80101 gagaagatac ttggcgggtt ctcttgatac ttgtttttca gccaatgatg ataagcaact
    80161 gtgttgatcg cagatgactt ttcttgcgaa gtaggactgc cattcgtatt gttattagaa
    80221 gaaccatcac caacccagtg agtcgcttta ttatctcctt cttttacctc tccataacga
    80281 tagtgtacat ttacttcatc ttctggacgg ttaaagtcag atgcataggt aactggatga
    80341 gtaaaccctg cattagaagt attcccagaa aactcctcaa aatttctgaa caaaacgtca
    80401 ttatcttcag caatcttatc ttccatcaca gtccagttgc tccaagctcc attagtgctc
    80461 gtacgataac ttgactgaat cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg
    80521 attaggattt tttctggatt tctattttct ccgccattgt ctttatacaa tgtttcatag
    80581 ccatttttaa gccctagtgt aagcggagtt cctccgattg gtgtacgatt taatgctgta
    80641 ttctcacttc ccgtcaaacg attgatatca tttgtcaatg gaaagatgtc cgaactgatt
    80701 tgctcatggt tattgatagc tgtactatta tggtaaaaat tcaccatacc gattcgaata
    80761 tccagactcg ggtcagagag cagatcttta ctcatttcgt ttactgcctc aatcaacgca
    80821 gcatttttag tttgactatt ggtcccagcg gttaattcac tcatactcgc tgacttatct
    80881 agaacaaaaa cgatatcgat tggactgatt tcctttttct cgcccccgat gacatctaga
    80941 tagacattgt aaagggttgt tgcatcttca ggatgtagat cagatgctgt gctgcttggc
    81001 agaacaggtt ctacccattt tttgatgtac gccccgttat aatccaagta actgttttca
    81061 aaattccgtt catttcccca aagctgaacg gtttgagctg gaacgtttct atcttcttcg
    81121 cctgcagttg atccattatt agtagcatag tcgtaatttc gccagttcgc tcccccgttt
    81181 gtataatcac tatcatcgat caagttctct ccgtcatatg gcgagccttt gtctccttga
    81241 tagcgttcat tgctttgtgt ccaatttcct aacacttttg tatagtcatt cgttgtaaac
    81301 ttcatctatt ctttcatcaa ccaccacttg aagaggtagt tacccttcgt tcacatcggg
    81361 gatcttttct gtttcaaaaa tcaatgtgcc ggtttctgct tcttttgaat aaacttttcc
    81421 gacataccat tcttgaccat cgatcgtctc gacttttagg tcttctccat cttcatcata
    81481 ggaggataga cctgttccac gaacgttttt tacggtacca atcccggcgg ctgccgcatc
    81541 gattgctaaa cgtattctac cttcattggc actttccttt ttttcaaaag ccagatgcca
    81601 ttcaagggtt tcttcttttt caatatactt cccttcaatt tttgcatagt cctcatctaa
    81661 gaatacctca tcctcctttg tttctgttga ctcagcagct acatccaggg tcgtcatatg
    81721 atagactgac tggaaatatg gtccaaatag caaactgaca gttactaact gcaaaagctt
    81781 caattttaac cctttcacat ccttatactc ctttcaaaaa tatttgtctt ctttcacaac
    81841 aatcaacaaa acaatgccca tctaattata atttaattta attttaattt taaatcaaat
    81901 gata
//
LOCUS       DAXLPY010000004        69787 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.004, whole genome shotgun sequence.
ACCESSION   DAXLPY010000004 DAXLPY010000000
VERSION     DAXLPY010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 69787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.004"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(10..126)
                     /locus_tag="ACF3UF_000295"
     CDS             complement(10..126)
                     /locus_tag="ACF3UF_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFD3670454.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(199..1155)
                     /locus_tag="ACF3UF_000296"
     CDS             complement(199..1155)
                     /locus_tag="ACF3UF_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3670455.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1326..1694
                     /locus_tag="ACF3UF_000297"
     CDS             1326..1694
                     /locus_tag="ACF3UF_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFD3670456.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            1864..2295
                     /gene="mraZ"
                     /locus_tag="ACF3UF_000298"
     CDS             1864..2295
                     /gene="mraZ"
                     /locus_tag="ACF3UF_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFD3670457.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            2316..3275
                     /gene="rsmH"
                     /locus_tag="ACF3UF_000299"
     CDS             2316..3275
                     /gene="rsmH"
                     /locus_tag="ACF3UF_000299"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFD3670458.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            3280..3681
                     /gene="ftsL"
                     /locus_tag="ACF3UF_000300"
     CDS             3280..3681
                     /gene="ftsL"
                     /locus_tag="ACF3UF_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFD3670459.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRRVK"
     gene            3682..5874
                     /locus_tag="ACF3UF_000301"
     CDS             3682..5874
                     /locus_tag="ACF3UF_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFD3670460.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            5900..6862
                     /gene="mraY"
                     /locus_tag="ACF3UF_000302"
     CDS             5900..6862
                     /gene="mraY"
                     /locus_tag="ACF3UF_000302"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFD3670461.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            6876..8237
                     /gene="murD"
                     /locus_tag="ACF3UF_000303"
     CDS             6876..8237
                     /gene="murD"
                     /locus_tag="ACF3UF_000303"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFD3670462.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            8263..9351
                     /gene="murG"
                     /locus_tag="ACF3UF_000304"
     CDS             8263..9351
                     /gene="murG"
                     /locus_tag="ACF3UF_000304"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFD3670463.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            9366..10586
                     /locus_tag="ACF3UF_000305"
     CDS             9366..10586
                     /locus_tag="ACF3UF_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFD3670464.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            10742..12067
                     /gene="ftsA"
                     /locus_tag="ACF3UF_000306"
     CDS             10742..12067
                     /gene="ftsA"
                     /locus_tag="ACF3UF_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFD3670465.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            12090..13331
                     /gene="ftsZ"
                     /locus_tag="ACF3UF_000307"
     CDS             12090..13331
                     /gene="ftsZ"
                     /locus_tag="ACF3UF_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFD3670466.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            13348..14025
                     /locus_tag="ACF3UF_000308"
     CDS             13348..14025
                     /locus_tag="ACF3UF_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFD3670467.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            14039..14638
                     /locus_tag="ACF3UF_000309"
     CDS             14039..14638
                     /locus_tag="ACF3UF_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFD3670468.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            14719..14940
                     /locus_tag="ACF3UF_000310"
     CDS             14719..14940
                     /locus_tag="ACF3UF_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFD3670469.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            14989..15771
                     /locus_tag="ACF3UF_000311"
     CDS             14989..15771
                     /locus_tag="ACF3UF_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFD3670470.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            15792..16499
                     /locus_tag="ACF3UF_000312"
     CDS             15792..16499
                     /locus_tag="ACF3UF_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFD3670471.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDIGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            16761..19559
                     /gene="ileS"
                     /locus_tag="ACF3UF_000313"
     CDS             16761..19559
                     /gene="ileS"
                     /locus_tag="ACF3UF_000313"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFD3670472.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(19608..21134)
                     /gene="zwf"
                     /locus_tag="ACF3UF_000314"
     CDS             complement(19608..21134)
                     /gene="zwf"
                     /locus_tag="ACF3UF_000314"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFD3670473.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(21149..21796)
                     /locus_tag="ACF3UF_000315"
     CDS             complement(21149..21796)
                     /locus_tag="ACF3UF_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFD3670474.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(21980..22309)
                     /locus_tag="ACF3UF_000316"
     CDS             complement(21980..22309)
                     /locus_tag="ACF3UF_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFD3670475.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            22486..23214
                     /gene="sfsA"
                     /locus_tag="ACF3UF_000317"
     CDS             22486..23214
                     /gene="sfsA"
                     /locus_tag="ACF3UF_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFD3670476.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            23230..24243
                     /locus_tag="ACF3UF_000318"
     CDS             23230..24243
                     /locus_tag="ACF3UF_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3670477.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            24243..25520
                     /locus_tag="ACF3UF_000319"
     CDS             24243..25520
                     /locus_tag="ACF3UF_000319"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD3670478.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            25583..28285
                     /locus_tag="ACF3UF_000320"
     CDS             25583..28285
                     /locus_tag="ACF3UF_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3670479.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            28437..28754
                     /locus_tag="ACF3UF_000321"
     CDS             28437..28754
                     /locus_tag="ACF3UF_000321"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3670480.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            28784..29104
                     /locus_tag="ACF3UF_000322"
     CDS             28784..29104
                     /locus_tag="ACF3UF_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3670481.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            29212..30672
                     /locus_tag="ACF3UF_000323"
     CDS             29212..30672
                     /locus_tag="ACF3UF_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3670482.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            30740..30961
                     /locus_tag="ACF3UF_000324"
     CDS             30740..30961
                     /locus_tag="ACF3UF_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670483.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            30992..31174
                     /locus_tag="ACF3UF_000325"
     CDS             30992..31174
                     /locus_tag="ACF3UF_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFD3670484.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            31174..31587
                     /locus_tag="ACF3UF_000326"
     CDS             31174..31587
                     /locus_tag="ACF3UF_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFD3670485.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            31710..32891
                     /locus_tag="ACF3UF_000327"
     CDS             31710..32891
                     /locus_tag="ACF3UF_000327"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3670486.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(32962..33126)
                     /locus_tag="ACF3UF_000328"
     CDS             complement(32962..33126)
                     /locus_tag="ACF3UF_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670487.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            33280..33353
                     /locus_tag="ACF3UF_000329"
     tRNA            33280..33353
                     /locus_tag="ACF3UF_000329"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33314..33316,aa:Arg,seq:cct)
     gene            complement(33422..34561)
                     /locus_tag="ACF3UF_000330"
     CDS             complement(33422..34561)
                     /locus_tag="ACF3UF_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3670488.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            34733..34867
                     /locus_tag="ACF3UF_000331"
     CDS             34733..34867
                     /locus_tag="ACF3UF_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670489.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(34860..35496)
                     /locus_tag="ACF3UF_000332"
                     /pseudo
     CDS             complement(34860..35496)
                     /locus_tag="ACF3UF_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(35609..36244)
                     /locus_tag="ACF3UF_000333"
     CDS             complement(35609..36244)
                     /locus_tag="ACF3UF_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFD3670490.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(36278..36739)
                     /locus_tag="ACF3UF_000334"
     CDS             complement(36278..36739)
                     /locus_tag="ACF3UF_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFD3670491.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(36869..37300)
                     /locus_tag="ACF3UF_000335"
     CDS             complement(36869..37300)
                     /locus_tag="ACF3UF_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFD3670492.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDK
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(37318..37638)
                     /locus_tag="ACF3UF_000336"
     CDS             complement(37318..37638)
                     /locus_tag="ACF3UF_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3670493.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            37937..38713
                     /locus_tag="ACF3UF_000337"
     CDS             37937..38713
                     /locus_tag="ACF3UF_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFD3670494.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            38728..38931
                     /locus_tag="ACF3UF_000338"
     CDS             38728..38931
                     /locus_tag="ACF3UF_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3670495.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            38947..39285
                     /locus_tag="ACF3UF_000339"
     CDS             38947..39285
                     /locus_tag="ACF3UF_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFD3670496.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            39272..39451
                     /locus_tag="ACF3UF_000340"
     CDS             39272..39451
                     /locus_tag="ACF3UF_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670497.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(39494..39964)
                     /locus_tag="ACF3UF_000341"
     CDS             complement(39494..39964)
                     /locus_tag="ACF3UF_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670498.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            40051..40749
                     /locus_tag="ACF3UF_000342"
     CDS             40051..40749
                     /locus_tag="ACF3UF_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFD3670499.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            40927..41268
                     /locus_tag="ACF3UF_000343"
     CDS             40927..41268
                     /locus_tag="ACF3UF_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670500.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            41261..41932
                     /locus_tag="ACF3UF_000344"
     CDS             41261..41932
                     /locus_tag="ACF3UF_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFD3670501.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            41938..42624
                     /locus_tag="ACF3UF_000345"
     CDS             41938..42624
                     /locus_tag="ACF3UF_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFD3670502.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            42627..43376
                     /locus_tag="ACF3UF_000346"
     CDS             42627..43376
                     /locus_tag="ACF3UF_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3670503.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            43388..43657
                     /locus_tag="ACF3UF_000347"
     CDS             43388..43657
                     /locus_tag="ACF3UF_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670504.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            43662..43826
                     /locus_tag="ACF3UF_000348"
     CDS             43662..43826
                     /locus_tag="ACF3UF_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670505.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            43819..44121
                     /locus_tag="ACF3UF_000349"
     CDS             43819..44121
                     /locus_tag="ACF3UF_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670506.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            44118..44279
                     /locus_tag="ACF3UF_000350"
     CDS             44118..44279
                     /locus_tag="ACF3UF_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFD3670507.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            44276..44581
                     /locus_tag="ACF3UF_000351"
     CDS             44276..44581
                     /locus_tag="ACF3UF_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670508.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            44581..44937
                     /locus_tag="ACF3UF_000352"
     CDS             44581..44937
                     /locus_tag="ACF3UF_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFD3670509.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            44897..45142
                     /locus_tag="ACF3UF_000353"
     CDS             44897..45142
                     /locus_tag="ACF3UF_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670510.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            45139..45558
                     /locus_tag="ACF3UF_000354"
     CDS             45139..45558
                     /locus_tag="ACF3UF_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFD3670511.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            45555..46112
                     /locus_tag="ACF3UF_000355"
     CDS             45555..46112
                     /locus_tag="ACF3UF_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFD3670512.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            46109..46405
                     /locus_tag="ACF3UF_000356"
     CDS             46109..46405
                     /locus_tag="ACF3UF_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670513.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            46482..46895
                     /locus_tag="ACF3UF_000357"
     CDS             46482..46895
                     /locus_tag="ACF3UF_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFD3670514.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            47204..47356
                     /locus_tag="ACF3UF_000358"
     CDS             47204..47356
                     /locus_tag="ACF3UF_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670515.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(47353..47628)
                     /locus_tag="ACF3UF_000359"
     CDS             complement(47353..47628)
                     /locus_tag="ACF3UF_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670516.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            48124..48288
                     /locus_tag="ACF3UF_000360"
     CDS             48124..48288
                     /locus_tag="ACF3UF_000360"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670517.1"
                     /translation="MPATLNAYDGYDYRKKIVKKLYGATYGNVVSVLSVHHQASVTVA
                     EVEDAAVNGE"
     gene            48484..48651
                     /locus_tag="ACF3UF_000361"
     CDS             48484..48651
                     /locus_tag="ACF3UF_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFD3670518.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            48677..49021
                     /locus_tag="ACF3UF_000362"
     CDS             48677..49021
                     /locus_tag="ACF3UF_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFD3670519.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            49026..49307
                     /locus_tag="ACF3UF_000363"
     CDS             49026..49307
                     /locus_tag="ACF3UF_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670520.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            49410..49724
                     /locus_tag="ACF3UF_000364"
     CDS             49410..49724
                     /locus_tag="ACF3UF_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFD3670521.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            49702..51396
                     /locus_tag="ACF3UF_000365"
     CDS             49702..51396
                     /locus_tag="ACF3UF_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFD3670522.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            51416..52594
                     /locus_tag="ACF3UF_000366"
     CDS             51416..52594
                     /locus_tag="ACF3UF_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFD3670523.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            52557..53243
                     /locus_tag="ACF3UF_000367"
     CDS             52557..53243
                     /locus_tag="ACF3UF_000367"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFD3670524.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            53243..54403
                     /locus_tag="ACF3UF_000368"
     CDS             53243..54403
                     /locus_tag="ACF3UF_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFD3670525.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            54413..55288
                     /locus_tag="ACF3UF_000369"
     CDS             54413..55288
                     /locus_tag="ACF3UF_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670526.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            55285..55596
                     /locus_tag="ACF3UF_000370"
     CDS             55285..55596
                     /locus_tag="ACF3UF_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670527.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            55586..55939
                     /locus_tag="ACF3UF_000371"
     CDS             55586..55939
                     /locus_tag="ACF3UF_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFD3670528.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            55929..56330
                     /locus_tag="ACF3UF_000372"
     CDS             55929..56330
                     /locus_tag="ACF3UF_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670529.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            56323..56727
                     /locus_tag="ACF3UF_000373"
     CDS             56323..56727
                     /locus_tag="ACF3UF_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670530.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            56739..57347
                     /locus_tag="ACF3UF_000374"
     CDS             56739..57347
                     /locus_tag="ACF3UF_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFD3670531.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            57367..57729
                     /locus_tag="ACF3UF_000375"
     CDS             57367..57729
                     /locus_tag="ACF3UF_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670532.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            57732..57914
                     /locus_tag="ACF3UF_000376"
     CDS             57732..57914
                     /locus_tag="ACF3UF_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670533.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            57931..61362
                     /locus_tag="ACF3UF_000377"
     CDS             57931..61362
                     /locus_tag="ACF3UF_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFD3670534.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVKKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            61413..62150
                     /locus_tag="ACF3UF_000378"
     CDS             61413..62150
                     /locus_tag="ACF3UF_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFD3670535.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            62160..64451
                     /locus_tag="ACF3UF_000379"
     CDS             62160..64451
                     /locus_tag="ACF3UF_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFD3670536.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            64475..66601
                     /locus_tag="ACF3UF_000380"
     CDS             64475..66601
                     /locus_tag="ACF3UF_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670537.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            66618..66767
                     /locus_tag="ACF3UF_000381"
     CDS             66618..66767
                     /locus_tag="ACF3UF_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670538.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            66764..67210
                     /locus_tag="ACF3UF_000382"
     CDS             66764..67210
                     /locus_tag="ACF3UF_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670539.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            67212..67349
                     /locus_tag="ACF3UF_000383"
     CDS             67212..67349
                     /locus_tag="ACF3UF_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFD3670540.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            67387..67680
                     /locus_tag="ACF3UF_000384"
     CDS             67387..67680
                     /locus_tag="ACF3UF_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670541.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            67677..67901
                     /locus_tag="ACF3UF_000385"
     CDS             67677..67901
                     /locus_tag="ACF3UF_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFD3670542.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            67898..68923
                     /locus_tag="ACF3UF_000386"
     CDS             67898..68923
                     /locus_tag="ACF3UF_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFD3670543.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNPYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            69113..69186
                     /locus_tag="ACF3UF_000387"
     tRNA            69113..69186
                     /locus_tag="ACF3UF_000387"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:69147..69149,aa:Ile,seq:cat)
BASE COUNT        23874 a        11309 c        14393 g        20211 t
ORIGIN      
        1 attttatttt tacatgacac tcattacagc agtcaataca acagatccaa tcgttaaaat
       61 cagcattgtc caaatgacaa attttgttac tttagcaaaa gtacttgttt gttttttttc
      121 acgcattgtt ttcaacctcg tcattaatta gttgattcaa gtgtacaatc ttttttccat
      181 ttccacaaga gggctttttt ataaaaactt cccttttttt aaataatagg tagttacgat
      241 acaaataaat aatgttaata gaactagcca tataaaggca tcatcccttt cagcaatagg
      301 taacttaatg ttcattccat agatactgcc gacgattgtc ggtatagtta aaataatcgt
      361 taaagaagtt aaaattttca taatattatt cagattattc gatacgattg ctgaaaaagt
      421 ctgattcatt tgttctacta gttttaattg aatgcgagaa gtagtcattg cctgctctgt
      481 ttccaccaat acatcacgta aatgattttt caaagcatga ttttcttgga aaagtttatt
      541 ttgcgctagt tctttcaatg catctaaatt agcagaagtc gcttctctga aataaacgag
      601 gcttttttgg atatccatga tttgataaag ttgtttgttt tcagtggata cttgaagttt
      661 ggcttccaaa gtatcgcatt gagattgaag cgtagctaaa taactgttgt aagagagtgt
      721 gacctgccaa atgaattgaa agaagatatt gagattaggc gaaatatcac tttttggaaa
      781 ggtctggcta aagactttct ttaaaaacag tggttcatga ttcgtaattg tgataagctt
      841 ctttttgggc gtcaaaataa tagagagcgg gtatgtatcc acttgaaaat aaccgctagg
      901 acttgtttta gcaaaaggat attgtaacaa taataacgct ggctttgtca actttgattg
      961 attgaattct tctgtacggg aattttctgc atcgtccaat atggaagtga tgtaatctga
     1021 cggaatttca aattgatgtg tcagctgatg aatctcttct tgattaggac gttctacaca
     1081 ataccagatc gtttggtcag tttcctttcc ggtattacgc agtttctcat tatctaatgt
     1141 aaaatatttg atcatgattt tcctcctgtt gcctgtttct tttattataa cggataggga
     1201 attggaatac atggaatgtg tttgtaagat atagaatata actgcataaa tttaaataaa
     1261 atgaaacagt tgtgtaaagt atatacagta tacttgaagc aacgataaaa aaggagttta
     1321 cgttcatggg cacattcaca ccacttatct tgttttggta tatttacccg gtaatcgttt
     1381 tgtttggttg ccaatttctt gtaaaattat tttcgttaaa tcgtcgtttt aaaataaaag
     1441 cccctgattt ggcgattcct tttttgtggg gcggtatgca tgcattgtct agaaatacag
     1501 ggacaatttc tatcttaccg tttttcttta tttctgtttt gctaatggga atttgtattg
     1561 ctgttttcca agcatattat tatgaagaaa ttatttatcc gcgttatttc aagatgactt
     1621 ggcgtttggt ttttctgttg acaatcgtct tgtacgctgt cttgatcatt gtgaacatac
     1681 tttcttacct atgaaaaaaa tagaaaagct gtaaaaagtc ttttaaaagg ctttttgcag
     1741 cttgattttt aaaaaaatgt ttatgaataa aaaaagttgt tcccggattt cccagaaaag
     1801 gtggtagaaa gtgggggatt gtggtagact aattttagtt agtggaggaa tggggggctt
     1861 tcaatgttga tgggtgaatt ccaacataat attgatgcaa aaggacgttt aatcgtgccc
     1921 tcaaaacttc gtgaagaact tggcgaaaag tttgttctga cacgcggatt ggatggctgt
     1981 cttttcggct atccgatgag cgaatgggaa aatctggaag ctaaactgaa cgaaatgccg
     2041 ttggctaaaa aagacgcacg tacttttgtg cgattcttct attcggctgc cactgaatgc
     2101 gaacttgata aacaaggacg aatcaatata cccagcacgt taagaaatta tgcagctttg
     2161 acaaaaggtt gcgtagtcat cggtgtatct aaccgaattg aaatttggga tgagacacga
     2221 tggcaagatt tttctgcagc agcagaagag aactttgacg aaattgctga aagtatgatt
     2281 gatttcggac tataagaata ggaagaggct gactaatgac tgaaacattt caacactata
     2341 cagtcatgtt gaaagaaacg gtagatggat tgaacatcaa accggatggc gtttatgtag
     2401 actgtacact cggcggtgcc ggacatagtg aatatttatt aagccaacta agttctaaag
     2461 ggcatctgta tgcgtttgac caagatcaaa aagcaatcga tcacgccaag ctgcgtttag
     2521 cttcttatgt cgaacaaggt atggtcacat ttatcaaagc gaacttcaga gaattagaag
     2581 aacgcttgag tgagcatgta gataaggtag acggcatttt gtatgatcta ggggtttcct
     2641 ctcctcagct agatgaagca gaacgtggat ttagttatca tcaagatgca ccgttggata
     2701 tgcgcatgga tcagtcagct cctttatccg cttatcacgt aattaatgaa tattcctacc
     2761 atgaattagt aaagattttc ttccgctatg gcgaggagaa attttccaaa caaattgctc
     2821 gtgaaatcga acgagtacga aaaacaaaac caatccaaac aactggtgag cttgtcgaaa
     2881 tcattaaaca agtcatccca gctcccgcaa gaagaaaagg cgggcatcct gcaaaaagaa
     2941 tttttcaagc tgtgcggatt gcagtaaatg acgaactcgg tgccgaagag gcctctttag
     3001 aacaggcaat ccggttattg aaagtcaatg gaagaatcag cgtaatcaca ttccattcat
     3061 tggaagacag aattgtcaaa agtatgttta aagaatatag tacggtacaa gatctaccac
     3121 cgggacttcc tgtcatacct gacgaattcc aaccagaact gaaagtcatt actcgtaaac
     3181 caatccttcc ttcagaggaa gagctaacag aaaacaatcg atcacgcagt gcaaagttac
     3241 gtattgcaga aaaaataaga atgaaagagg agtagaatga tggcagaatt aaagaaaatg
     3301 caagattacg aatatgattt acctgaattg gtggatcagc cggaacaaca aatgcctgat
     3361 tcttcttcga atcaagaaat cattcttcca caatcaccgg caaaacgatt aaagcagatt
     3421 tctgctttgg aaaaaattgc tgtggcaagc gtggcgattg ctattgttgc tttatgtgtt
     3481 ttaacagtta tgctgcgcac aaatatcagc ggagctgaaa aagaaatcac gtcaatacaa
     3541 acagaaatca atgataaaaa gcaagaaaaa acgagtttag aacaagaaaa aaacgaactt
     3601 tctcgtactg aacggattaa acaaatcgca gaagaaaaag gattgtctat taatgacgac
     3661 aatttaagga gagtgaagta aatgagtctt aaaaataaaa ttcggcggtt tatggaaaag
     3721 aaaaatctaa atccgatgaa caatcgcaaa aaagtaggta tcattttatt tgctacgagt
     3781 attggattgt tctttttatt tgccgtccgt ttctcgtata tcgttattgg aggtcatgtt
     3841 gctggtacct cattagctga aaaaacaaaa cagttgtacc aaggaagtga agtagtaaaa
     3901 gcaaaaagag gaacgattta tgatcgtaac ggtgtggcgc tcgcagaaga tgcctcctct
     3961 tattcaatta aagcgatact ctcaaaaaca tatacctctg gggataaaaa actgtatgtt
     4021 gaagaaaaga attttgataa aatagcagaa atcctgcata agaatctttc tatagacaaa
     4081 aaagatgcac tgaatatttt agaggacggc gcaaaaaaag agctgtatca agttgaattt
     4141 ggtagctatg ggaaaaatat ctcccaagaa accaagcaaa acatcgaagc ggacatgaaa
     4201 aaagaaggtg tcgctggtct ttattttgtc gaccatcagg ctcggatgta tccaaatggc
     4261 gtcttttctt ctcattttat tggatacgca gttccagaca aagatgagaa tggcttagtt
     4321 ggtaaactag gtttggagtc tgcttacaat gatatcttga gcggtaaaga tggtaagatt
     4381 atttatcaaa aagataattt tcaaaatcct ctgccaggta cagtggcaga agaagaaaaa
     4441 gctgtcgacg gacaagatat ctacacgact ttagacagca gactacaaag ttatttagaa
     4501 acactgatgg atcaagtaaa tgaagaatat cagccagaag aattgacagc agtcctgatg
     4561 aaagcaaaaa ccggagaaat cttggcaatg ggacaacgac ctactttcaa tcctgaaaca
     4621 atggaaggat tgactggaaa agatgctatc tggcgtaatt tcttggtaca agatagttat
     4681 gaaccaggat caaccatgaa agttttcact actgcagctg ctatcgaaga aggagaattc
     4741 aacgagaatg aaaccttcca atctggaaaa atccaagtag aagatgctac gatcaatgac
     4801 catgactttg gtgaaaaagg tgtgctgacc atgcgtcaag ctctttcatg gtcaagtaac
     4861 gtcgggatgg tcatactgga acagcgatta ggcggacgat ggtataacta tttacaaaaa
     4921 ctgggatttg gacaaagtac tcattctgga ttagatgatg aagtaaacgg tgctttacct
     4981 acattaaata ttgtcgaccg agcaatgagt gcttatggac aagcggtagg tgtgacgaat
     5041 ttccaaatga tgaaagcttt cacttctatt gcgaataacg gtacaatgat tcaacctcga
     5101 tatatcagca aagtggtgga tccccaaact ggagaagagc gaacaactca aacagaagtt
     5161 ctagggcaac ctttttcaaa agaaacaaca gaaaaagtcc gtgaatatat gagagatgtt
     5221 gtcgaaagcg aaaactacgg tagtgcttat ggtgtatata gtgtacctgg atacaatgta
     5281 tcggcaaaaa ccggaacagc ccaaatcgct tctgatacag ggggatatca aacaggagat
     5341 acagcctacc tgtattcgat tgtggagatg gttccttctg aagatccaga ctatgtcttg
     5401 tatctaacaa tgaaacaccc taagacatat gatcgaatgg cattggctaa aatcgcaaat
     5461 ccattgatga aacgggcaat ggattttaaa gaaactgaag aagattcaga tacagaaaca
     5521 aaaacagaaa aagtatccgt agccgattat cgtaatcttg aagcggacgt tgcagcagct
     5581 gatgctcaaa aaagtggact gcaacctgta gtgatcggta atggtaaaaa agtacaaaaa
     5641 caatctactg ccaacggtga tcagttgatc tctggagaaa aactgatcct atatactggt
     5701 ggtgataagc tgatgcctga cgtaacagga tggtcaaaag cagatatcat gaagctgggg
     5761 aaaatcctcg gtattgaagt tagttttgat ggagatggtt attgtgtcaa acaagaactt
     5821 gctccatatg aaaaaatcac tgaagacaaa cttagtttta ctttagaaga ataagaagag
     5881 aaataggaga gaaaagagca tggaatggac acaagcattg attcccattg tcagcagttg
     5941 tgcaatgaca attgccgcaa tgccgctatt tattggttat tttcaaatga aaaagcaagg
     6001 tcaggcgatt cgtgaggagg gaccaaagtg gcacaatagc aaagccggaa ctcctacaat
     6061 gggcggctta gtgtttctga tcggctctat tttgacagga atttgggttg gagcttggca
     6121 aaaacagcta actcctactc ttttcatctt gctttttgta ttagcgttat acggagtaat
     6181 cggctttctt gatgatttta taaaaatatt caagaaaaga aacatgggac tgaactcgaa
     6241 gcagaaattg attggacaga ttctaggggg aatcatcttt tatcttgttt accgttctga
     6301 aggttatcca ggtgtattga atttcttcgg actagatcta cctttaggaa tcatttatgg
     6361 tattttcgct ctcttctggc ttgttggatt ttcaaatgca gtaaatctga cagatggcat
     6421 cgatggatta gttgctggct taggaagtat ctcttttgca gcttacggtc taattgcttg
     6481 gcatcagcat cagtatgatg tattaatcat ttgcttaagt gttttaggag gtttactggg
     6541 tttcttcgtc tacaacagaa aacctgccaa gatttttatg ggagatgtcg gttcattagc
     6601 gttgggcgga cttttagcgg caatttctat aatgctaaac caagaatgga cattgctttt
     6661 gattggtttg atctatgtta tggaaacagc aagtgtgatg cttcaagtta cttcctttaa
     6721 gcttacagga aaacgaattt ttaaaatgtc tccaattcat catcactttg aaatgtgcgg
     6781 atggtcggag tggaagattg atacagtttt ttggttgatc agcattgtga cttcgttgat
     6841 cacattatgg atcgtttggt aggagatgac gggaaatgaa aaaaatatca acatatgaaa
     6901 ataagaaagt gcttgtctta ggactcgcaa aaagcggagt aagtgcggcc aaattattac
     6961 atgaattggg cgcacttgtc accgttaatg atggaaaacc ttttgacgaa aatccggaag
     7021 cacaagagct gctttcttta gggataaaag taataacagg tagtcatcca atcgaattgt
     7081 tggatgaaga attttcattg atggtcaaaa atccagggat tccctacagt catcctttag
     7141 tagcaaaagc ccaagaaatg ggtattccgg taattacgga agttgagcta gcttacgaag
     7201 tagcggaatg cccaattatt gggattacag gaacgaacgg aaaaacaacg acaacaacga
     7261 tgacaggact actactgaat gcaggagcag atcaaggaat tgcacgttta gcgggtaata
     7321 ttgggtatcc agcaagtggt gtagcgcaag aagcaaaatc agaagataaa attgtgatgg
     7381 aattgtctag cttccaactc atgggaatca cagatttccg ccctcatata gcggtgatta
     7441 ccaatatcta tgaagcacat attgattatc atggtacaag aaaagaatat gtcaaagcta
     7501 aatggaacct tcaaaaaaac atgacagaaa aagattatct gatccttaac tggaatcagt
     7561 cagaactaca agaattagcg caaagaacaa aagcacgcgt actgcctttc tcgacaaaag
     7621 aagtgttgga agacggtgtg tatgctgacg attactcaat atactataaa aaagaaaaaa
     7681 taatggaaat atctgaactt ggcgtaccag gtaagcataa tgtagaaaat gcactagctg
     7741 ctatttctgt agcaaaattg tatggtatat caaatgaagc tatacgagaa acgttgcatt
     7801 ttttccatgg cgtaccacat cgtacgcaat atgtaggaga aatccaaggc agaaaatttt
     7861 ataatgattc aaaagcaacc aatattttag cgactaaaat ggctctaagt ggatttgaaa
     7921 cgtctaaggt cgtgttattg gctggcggat tagacagagg aaatacattt gatgaattaa
     7981 ttccttcatt aaaaggaatc aaagcaatgg tcgtatttgg ccaaacaaaa gaaaagttga
     8041 tggatgctgg aaaaaaagca ggcatcgaga caatagtaac agccgattct gtagaacaag
     8101 cagttccttt agcattagaa aacagtacag atggtgatgt agttttatta tcaccagcga
     8161 atgccagctg ggatcaatac ccaaattttg aaactagagg aaacagattc atggaagctg
     8221 tgaaccgatt aaaatagaaa aagtagaagc gagcgataaa aaatgaaaat tttggttaca
     8281 ggcggaggaa cagggggaca tatttatcca gctcttgcct ttgtcaatta tgtaaagact
     8341 caagaaccga atgctgaatt catgtatgtg ggagcaaaac gaggtctaga aaacaaaatc
     8401 gtccctgata caggaatgcc tttccatacc ttggagattc aaggatttaa acgaaaaatt
     8461 tccatgcata acatcaagac ggtccgattg tttcttaaga gtatccgtca agcaaaaaaa
     8521 atcctcagtg attttcaacc agatatcgtt atcggtactg gaggatatgt ttccggagcg
     8581 gtagtgtacg ctgcagccaa aatgggtatt ccaacagtta tccatgaaca aaacagtgta
     8641 ccaggtgtta ccaataaatt tttaagccga tatgtggatc ggatcgctct ttcatttaaa
     8701 gatgcggctt ccttttttcc tgaaaacaaa gcagttcttg taggtaatcc tcgagcacaa
     8761 gaagtagcag atactaaaaa atcagatatt ttgaaaacat ttgatttgga tccagaaaag
     8821 aaaacagtct tgatttttgg cggtagtcaa ggagcactta aaatcaatca agcagtatca
     8881 gtttttttaa gtgaatatat tccttcttct taccaagttt tgtatgcttc aggagataga
     8941 tattatgaag agatcctaaa taaaataaat cctgaaatac aaaatattag tgtccagcct
     9001 tatatcaaaa atatggcaga ggtcatggct tccagtgatc tgctggtggg gcgtgctggt
     9061 gcaacttcga tcgcagaatt cacagctctg gggttaccgg cagtgttggt tcccagccca
     9121 tatgttacga atgatcatca gactaaaaat gcaatgagtc ttgttcacgc aggagcagca
     9181 aaaatgattg cagataatga actaacaggt gaatcactaa gtcagacagt caacgaaatc
     9241 atgggtgatg aagaattgca aaagcaaatg tgccgagctt ctaaagaaca aggaatccct
     9301 gatgcttcaa aacgtcttta tgacttagta aaacaaataa tcaaaaaata aaggcggtgg
     9361 tcttagtgag taagaaaaaa gaaccaaaaa aattgtctca tccgtcttct gatgaaaaca
     9421 atttgactcc ttggcaaaag gctaaccgaa aatatctggc agaacaagag atgaaaaacc
     9481 aagagccaaa aaaagaagac ataacattag atacacccct ttcagattct gaagaagaaa
     9541 aaacggttca agaggaacag caagaagaaa gccagtccga gaaaaaaatc gaattttttg
     9601 aagagatcaa gcaaaagaaa aacggtggac catataacgg ttcttttttg aaccggctgc
     9661 ccaatttaaa aagtcaacgg cacaaagtac tatttcgtcg gttagctttg atcatcactg
     9721 tattgggtat accgctgatt tttttgatct attatgtttc tccttatagc aaattacaag
     9781 cagttgcagt atcaggcaat aagacagtca acagccaaga aatcatctct gatacaaaat
     9841 tgtcattagg agaaaatgtt tggggacagt attttcatcg atctacttat atcgatcgcc
     9901 ttaaaaaagc acagccaaga atcgaaacag caaatataca tttcaaaggg atgaatgaat
     9961 tcgatttgga tgtaacagaa tataaagaga ttgctttgat cgcaaaaaac aatcaatact
    10021 acccagtgat tgaaaatgga acagtattag atgaaaaagt agcaaatcct acaaaaaatc
    10081 tccctatctt ggaagagttc aaagactctg caaaaatcaa agaattaaca aagcaataca
    10141 atcagttatc atcagaatta caaaaagcaa tttctgaaat caagtacacg ccaagagcaa
    10201 gcaataaaaa tctgatccaa ttgaatatga atgacggcaa tcaagttatt gtaaatatca
    10261 ataatcttgc gaaccaaatg aaatattatt cgcaagtagc caaagatatg gatgaaaaag
    10321 gtgtgatcga catggaagtt ggtatcttct cgcatcctta cggtagcact caagaaacgg
    10381 aagaatcggg ccaatcggaa gaaacaactg aaagtgaaga aaatgcggat caaacaaacg
    10441 aatcaagtga agaggcagaa acgcaaaaag cacaaacacc tggatcgtct agcacaaacg
    10501 gatcatctga ttcaaatgat tcaagtgaaa caagtcaaat agaagataat ccaagtacaa
    10561 ctccgtcaag tttaaatgaa aattgataaa acaactttaa aaagtaagaa tgtactttct
    10621 aaaaaccagt aatttatggt agaattggaa gcagtgaata tatctattaa taagtatatt
    10681 ttaaaacgga cgctagttgt tcgcttgtat atggaatagt aagtaggagg gaatcccatt
    10741 catggcaaaa acaggaatgt atgtaggcct tgatattgga acgacatctg ttaaagttgt
    10801 cgtggctgaa tatatcgaca gccaaatgaa tattattgga gtaggaaacg caaaatcaga
    10861 agggattaac cgaggcatta tcgttgatat cgataaaacg gtccaagcga tacaacgagc
    10921 agtacgacaa gcagaagaaa aagcaggtat ccagatcaaa ggcgtaagtg tcggtttgcc
    10981 agcaaacatg cttgaagtag aaaattgcca gggaatgatt gcagttaacg gagattcaaa
    11041 ggaaatcacc gatgaagatg tcagaaatgt ggcttcagct gcccttgttc gttcaatacc
    11101 tcctgaacgt caaatcgtgt caatattgcc acaagatttt actgtcgatg ggttcgaggg
    11161 aatcaaagat cctcgtggaa tgatcggcgt aagattagaa atgtacggtc tgttgtttac
    11221 aggacctaaa acgatcatcc ataacatacg taaatgcgtg gaaaatgccg gattaatcgt
    11281 caacgaaatg gtgattactc ctttagcgct gactgaatca attctttctg acggagaaaa
    11341 agattttggt acgatcgtca ttgatatggg tggcggccaa acaacaacgg ctgttatgca
    11401 tgataagcaa ttgaagttta ccaatcttga ccaagaaggt ggcgaatttg tcactaaaga
    11461 tatctctatt gtattaaata cgtcatttaa caatgcagaa gcgttgaaaa taaactacgg
    11521 ggatgcatac ccagaacgga catcaccaga tgaagaattt ccagtagatg tgattggtca
    11581 gtcagaacca gtgaaagtcg atgaacgcta cttgtcagaa attatttcag ctcgaatgga
    11641 acagattttc aacaaagcaa aagatgcatt ggaccaaatc gaagcattag agttgccagg
    11701 tggcgtcgta ttgacaggcg gagctgctag tcttcctggt gttgtggact tggcacaaga
    11761 aatcttcggc gtaaatgtaa aattgtatgt tccaaatcac atggggctga gaaacccggt
    11821 atttacaaat gtaataagta tcgtggatta ttcagcaaac ttgagtgaag tgtatcaatt
    11881 ggcaaaaatt gctgttacgg gtgaaacctc agcagctcgt caaatggtag ttgaacaaga
    11941 aacaacaaac acatatgaga gctatgaagc acctgaagaa acaatctacg atgagccgga
    12001 accaaaagag tccggagaaa atgtaaaaaa taaaatcaag ggtttcttta caaatatttt
    12061 tgattaattc atcctgggag gaataagata tggaattctc aattgataat aatatcaatg
    12121 acggcgcagt aatcaaagtc atcggagtcg gtggtggcgg tggaaatgct gtaaaccgaa
    12181 tgattgaaga aaacgttaaa ggtgttgaat tcattacagc caacacagac gtgcaagcat
    12241 taaaaaattc aaaagctgaa acagttatcc aattaggccc caaatatact cgtggtttag
    12301 gtgctggttc tcagccagaa gttggacaaa aagcggcaga agaaagtgaa caatccttac
    12361 gcgaagcttt agacggtgca gatatgattt tcatcactgc aggaatgggt ggaggaaccg
    12421 gtacaggtgc tgcaccaatc gttgcaggta tcgcgaaaga attgggcgca ttgactgttg
    12481 gtgtcgtgac acgtccattc acttttgaag gaccgaaacg tggccgtttt gctgcagaag
    12541 gtatcgctcg tttgaaagaa aatgtggata cattattaat tatctcaaat aaccgtttat
    12601 tagaagttgt agataaaaag acaccgatgc ttgaagcttt ccgtgaagca gataatgttt
    12661 tacgacaagg tgtacaaggt atctctgatt tgatcacagc gccaggttac gttaaccttg
    12721 actttgctga cgtgaaaaca gtgatggaaa accaaggtac agcattgatg gggatcggtg
    12781 tggctagtgg agaagatcgc gtagtagaag caacgaaaaa agcaatctcc tctccattgc
    12841 ttgaaacatc tattgatgga gctgaacaag tacttcttaa catcacaggc ggtttggata
    12901 tgacattgtt cgaagcacaa gatgcttcag atatcgtagc aaatgcagca actggcgatg
    12961 taaatatcat tctaggtaca tctatcaatg aagaaatggg cgatgaaatc cgtgtgacgg
    13021 tcatcgcaac aggtatcgat gaatcaaaaa aggaacgcaa gtctagccga ccagctagac
    13081 aagcacaaat gcaatcacct gctcaaaaga ctgtattaga tatggatcaa gctaaaccaa
    13141 cttcttcaga agaagaaaac agttttggcg attgggatat cagacgtgaa caaaatgttc
    13201 gtcctagagt tgatgattcc aattttgaca atatcgaaaa aaaagaattt gatacattca
    13261 accgcgaaga aacaaaatct catggcgatg atgaattaaa tacgccaccg tttttccgtc
    13321 gtaaaaaata aaggagagga agagcacatg attgctgaca acttgcagaa aatcaagcaa
    13381 gaaattcagg attcgtgtgc tcttgttcat cgtgatccga aagaagttac attagtagct
    13441 gtaacaaaat ctgttgaatc cgctcaagct gaagaattgg ttagagctgg cgttatgaat
    13501 tgtgcagaaa accgagtaga taaattatta gaaaagaaac aagatttatt tgattttcct
    13561 gaaataaagt ggcatttaat tggtaattta cagcgcagaa aggtaaaatt gattgtaaat
    13621 gaaattgatt actttcatgc gttggacagt ttaagattag cagaagaaat ccagaagcgg
    13681 ttagagaaag aattatcctg ttttattgaa gtaaatgttt ctggtgagga atcaaaacat
    13741 ggaatttcac cagatgagct tttaccgttt gtggaatctt tagctgcctg cacaaaaatc
    13801 aaggttgttg ggttgatgac tatggcgcct aaagaagctt ctgatgagca aatccataaa
    13861 gtgtttggta cgctgaaaga attgcgtgat cttgttcaag caaaaggtta tgcccatgca
    13921 ccatgtagtg aattaagtat ggggatgagt caagactttc aaattgcgat tgaagaaggt
    13981 gcaacattta tccgtgtagg aacagcgcta ttcaaagacg aataaaggag gaacaaaaat
    14041 gccgctttta aacagaggag caattgctaa ttttttcgga ttagctgatg aggaagagta
    14101 cgaataccaa gattatcctg aaacaacaaa aaaggctgta cagccaacta aaaaaaatac
    14161 aacacagaat caatcaactc attctgtatc tgctgcgaat actcatgaaa aacaaaaaac
    14221 ggcgacttca cgtcctgtaa cgcatgaaag tattcagccg gctgaaaaga aaaaagtaat
    14281 tgaactacat caatcaccta caaaaactgt agcgaaagaa agaacagctt caagaacctc
    14341 tacacaacct aaagcaaatc ttgctggaaa aatcactgta atggaaccaa gagcttattc
    14401 tgaagctatg gcgattgcta aacgaatcat tgctggagaa gcaaccttag tgaattttca
    14461 tttagtagaa gaaaaacaag cgagaagaat cgttgatttt ctaacaggaa cagtttatgc
    14521 actagatgga gatatcaaac gtgttggaga tgagattttt ctttgtacac cgactgggat
    14581 ggagattgac agttcaaccg ctcaatcttt tgcagatgcg aatttgtttg atctgtaaga
    14641 ggaggaacta cgatttatac tattgcacta ttacttcatt tacttcaacg ggcagcctat
    14701 ttctatagca ttatcttgat ggtatatgca ttgctctctt ggtttccagg cgggtatcaa
    14761 tcagggctag gacgattatt agctaagatc tgcgaaccgt atatcagttt gttcgatcgt
    14821 ctgcctttga ggattggacc cttggatttc acaattttag gggcaatcct gatcttgaac
    14881 ttagccgtac aaggtttagc acagatcgtt atatggataa ctgtccattt agtttattga
    14941 ttgaagcaac aaaatcttta ttctcagaat agataggagg ggaaaatttt ggatgcaaat
    15001 gtataccagc actttcgggc agatgaacgt acatttatcg attcggtagg cgattggatt
    15061 gaacaggttc aaggacaata tgcaccctat ctgaccgaat ttcttgaccc aagacaatcc
    15121 tatattttag aaacactgat tcgacaaagc agtgatttgc gtttcatgtt ttatggcgga
    15181 tatgaacagg cagaaagaaa aagatgtttg attttccccg attattacga acctgtagag
    15241 gaagattttg aaacagcatt gtatgaaatc cattatccta gcaaatttgc cagcctaagt
    15301 catgggaaaa tccttggaac tttagtggga acggggatca aacgctctta ctttggcgat
    15361 atcatctcgg acggtgatcg ctggcaagta tttattgcaa atgaggtgga tcattttgtt
    15421 gctgcacaag taacaaagat tggaaaggtt gctgtacgct tggaaccaat caaatacaca
    15481 gaaatgatta tgccgaaaga tagctggaca caagaaagag gaacagttag ttccatgcga
    15541 ctagacagtg tgatctctga gatttataat atttccagac agcggtccaa gcagctgatc
    15601 gaagctggta aagtaaaagt gaactggaca gaaaatacaa gacctgattt tgtacttgaa
    15661 ctattagata ttatttcagt cagaggttat ggcagagtcc agatccaaga acttgagggg
    15721 aagacgaaaa aagaaaagta cagggtactg ttcggtgtat tacgtaaata aaataaaaag
    15781 gtggtttact catggcttta actccattag atatccaaaa taagacattc ccgacaaaaa
    15841 tgcggggata taatcaagac gaagtagatg atttcttaga tttagttgtt cgtgactatg
    15901 aggaattgac tcaaagaaat cgagaattag aaaaagcagt caaacattct gaagaaaaac
    15961 ttgagtactt caatgaatta aaagatgctt tgaaccaatc aatcatcgta gctcaagata
    16021 cggctgataa agtaaaaaca agtgcaagca aggaatccga agtgatcgtt acttctgcac
    16081 aaaacaaagc agatgagtta gttgcgaacg ctgaaaaacg tgcacatcaa ttaacaactg
    16141 atgcagaaga aaaagcaaga aaaatcttga cagatgcaac agaaaaagca agacagcttg
    16201 cgacagaaac tgaagatctt aagaaaaaaa cacgagtatt ccatcaacgt atcagcttga
    16261 tgcttgagtc tcaattagaa caagtgaaaa gtccggaatg ggatgaaatt ttacaaccat
    16321 tctccagcta cgtgactgac agccatgaag tgatcaaaga agttttagca aaacagcttg
    16381 acaatgaaaa tgatactgat gtaaactcag acataggagt catagaagca cctatgacgg
    16441 catttgatac acaggctatt gatatctcga tcgtgcctgg tgaaaatgaa aacgagtaga
    16501 acagaaaagc actttgttat tcttaaagcg agccgatgag agtggaagtt cggtaagaca
    16561 ctgcatggtg aaagatcctc tacttgagac ctgcttttcc gaaattagag taagaagcag
    16621 cggctgacct cgttattggt cacagagagt ttgcactaga tagatgcaac taaatttggg
    16681 tggtaccacg gcatgttcgt cccttgcggc tgaacatgct tttttgtgtc cggaaaacaa
    16741 ataaaggagt gtatggttga atgaaaatga aagaaacctt gcaattagga aaaacaaaat
    16801 tccctatgcg tggtaatttg ccaaaccgag aaggcgagtg gcaaaaagaa tgggaagaaa
    16861 atcgaatcta ccaaaaaaga caagagttga acgaaggaaa acctagcttt gttcttcatg
    16921 atggacctcc atatgccaat ggtaatatcc atttaggaca ttcattgaat aaaatcagta
    16981 aagacattat cattcgttca aaatcaatgt ctggctatcg tgcaccatat gttccaggat
    17041 gggatacaca tggattgccg attgaacaag tattggctaa taaaggcgtg aaacgtaaag
    17101 aaatgtccat ggcagaatac ttggaaaaat gtcgtgaata tgcactttcc caagtagata
    17161 agcaacgagc agatttcaaa cgcctaggag ttgcaggaga ttgggaacat ccttatgtta
    17221 cattagatcc ttcttatgaa gctgcacaag tacgcgtatt tggtaaaatg gctgaaaaaa
    17281 gctatattta caaaggattg aaaccaattt actggtctcc gtcaagtgag tcttctttag
    17341 cggaagctga aattgaatat aaagatgtaa aatctccatc tatttttgta gctttcaatg
    17401 tcaaagacgg caaagatatt cttgatgaag atacagcttt tgtcatttgg acgacaacac
    17461 catggacatt gccagcaaac caaggtattg ctgtaaatcc aaaatttacg tatgtattgg
    17521 tggaagccga tggccgtaag tttgtcgtag cgaaagattt gctagaaaca gtccaatcag
    17581 aaatcggttg ggaaaatgta acagttctaa aagaatttgc tggacaagaa atggaatata
    17641 tgactgcaag tcatccattc tatgaacgtg aatcacttgt gattttaggc gatcatgtta
    17701 ctttagacgc tggtactgga ttagtccata ctgctccagg acatggggaa gatgactata
    17761 tcgctggtag caaatataaa ctatctgtag tgtcacctgt agactcaaaa ggattgttta
    17821 cagaagaagc acctggattt gaaggtatct tttatgacaa agcaaatcct atgatcactg
    17881 atctattaaa agaaaaagga gctttgctga agctagattt ctttactcat agttatcctc
    17941 acgattggcg gacgaaaaag cctgtgatct atcgggcaac tccacaatgg tttgcatcta
    18001 tcgataaatt ccgtcagaat attttggatg aagtagaaaa agtagagtgg gttatcccat
    18061 ggggtaaaac acgtttgtat aatatgatcc gtgaccgcgg cgattgggta atttcccgtc
    18121 agcgtgcatg gggagtacca cttccgattt tctatgctga aaatggagaa gcaatcatca
    18181 caccagaaac aatcgaacat gtggcaaaat tatttgctga acatggatca attatctggt
    18241 ttgaaaaaga agcgaaagaa cttcttcctg aaggatttac ccacccaggt tctcctaatg
    18301 gcgaatttac aaaagaaaaa gatatcatgg atgtctggtt tgattctggt tcttctcatg
    18361 aagctgtttt acgtcagcga ccagaattat cattcccagc agatatgtat ttagaaggat
    18421 cagaccaata tcgtggctgg ttcaactcaa gtatcacgac tagtgtggct atcaatggtg
    18481 tagcaccata caaatcagtt atttctcaag gatttgcttt agatggtgaa ggccgtaaga
    18541 tgagtaaatc tttaggaaac atcattgcac cagaaaaagt gatcaaacaa tttggtgcag
    18601 atatccttcg cttatgggta tctagtgtag attatgaagc agatgttcgt gtttctatgg
    18661 atatcttaag tcaagtggca gaagtatatc gtaaaatcag aaatacgatg cgtttcttat
    18721 tagcgaatac agaagatttc gatcctaaaa aagatactgt ttcgtacaat gatttacgtt
    18781 ctgtagacaa atatatgacc gttcgattga accaagtaat caaagaaatc cgagaagaag
    18841 ggtacgacaa atataacttc atgcatattt accgtacagt tatgaacttc ttgacggttg
    18901 atctatcgtc attctacctg gattttgcta aagatgtagt ttatattgaa gcagaagatg
    18961 attatcaacg tcgttgcatg caaactgttt tctatcaaac agctgtagct ttgacaaaat
    19021 tattgactcc tatcattccg catacagcag aagaaatctg gtcattcctg aaagaagaag
    19081 aggagtacgt tcagttaagc gagtttcctg gttatgaaga gtttgcaaac caagaagaat
    19141 tgatggatac ctggactgct ttcatggact tccgtgataa tgtcttaaaa gcattggaag
    19201 aagcaagaaa cagcaaattg attggtaaat ctttggaagc aaaactaact gtttatccaa
    19261 aacaacaagt tcgtgaaatg ttaaaagctt tggatgcaga tattgcacaa ttattgatcg
    19321 tttcaccaga ctactttgaa gttatggcag cagatgaaca agtgccagat aacgctatgg
    19381 tatttgatga tgttgctatt acagtggaaa aagcagacgg ggaaacttgc gatcgctgtc
    19441 gccaagttcg taaagatgta ggagtagatg aaaaacttcc tcatctatgc ggtcgttgtg
    19501 caaaaatcgt tgaagacttc tatcctgaag ctgtagctga aggattcgaa gaaaagtaaa
    19561 agggaaaagg gggtgtgaca tgttctttgt cacaccccct tttgttatca atcgtttaat
    19621 tttccacgtt cacgatacca gttatctggt tgccagatcc attcgaatcc gtctttttca
    19681 agtagttcga aagctgcttt aggtcccatt gatccagctt tgtagttggg aaaatccggt
    19741 tgtgtttggt cccaagcttt tcgaatgaca tccacgatat gccaagattg agcgacttct
    19801 tcccaatgag agaagttcgt tccatcacca ttcaacgcat ctaatagtaa tttttcgtaa
    19861 gcttctgggc tattttcaac catttctgca ctatttctaa attccaattt gattggttcc
    19921 gtttcaaatc cttgccctac ttctttccca ttcaaggata aagaaaatcc ttcagttggc
    19981 tgaatataga tcgttagaac attaggtgga agtgtcgtat cgtcacatgg ttcatcgaca
    20041 gatgttttga atacattaac aggaacttgt ttgaatacga tgttgatccg agtccctttt
    20101 tcagtcaaac gtttgcctgt acgtacatag aaaggaacac ctgaccaacg gaagttatcg
    20161 atagtgaatt tgcctgcgac gaatgtttca gtctctgatt gagcatccac tttgtcttct
    20221 tcgcgatagc ccttgaattg tacaccatcc aattcacctt gagcatattg cccgcgaacg
    20281 aagttttcta acacttcttc ttcgttataa atgcggatag ctttcaatgc tttgatcttt
    20341 tctgtacgga tttctttttc ggaaaatgct actggcggtt ccattgcaag taatgctaca
    20401 acctgtaaaa tatgattttg caccatgtct ttaagtgcgc cactatgatc gtagtagccc
    20461 ccgcgatctt ctacaccgag gttttcgcca aaagtaattt ggatattgtc gatatagcga
    20521 ttgttccatt gagcctcaaa aatattattg gcaaaacgga tagctgagat gttttggatc
    20581 atttcttttc ctaaataatg atcaatcctg aaaatatctt gttctgggaa tacttctctg
    20641 atttgctggt tcaattcaaa agcagactgg taatcagaac cgaacggttt ttctatgatc
    20701 aaacgattga agccattttt tgtcataata ttttgtgatt tcaaatgaga aacgatcgtt
    20761 ccaaaaaatt gaggtgccat agccaaataa tagacacggt taccgtttaa ttgatagtgt
    20821 ccatctaatc ggtcagacaa ttcttttaat gtctgataat gcgttgaatc atttacatca
    20881 tgggattgat agtaaaaatg gcttgcaaag gtagttgctt cttcatctga aggattcaat
    20941 gcacggattg tttctttgac aacttcacgg tagtgctcat cgctccaggg acggcgagcg
    21001 gttccgatta cagcaaaatg ctcgcctaaa tttccttttc tgtaaaggcg gaacaaagac
    21061 gggtacaatt tacgctgggc taggtcacct gtaccgccga atatcgtaaa caatacattt
    21121 ttttcattag acatgtggat acactccttt atattttatc gacaaaaatc gtgctggccg
    21181 ccttaaagct gacggggatt ttctttctat cattttggat agtgatcggt ccttcataag
    21241 ctgcgatgtc aacgatctca tattcttcgt tgatattcag gtcaatagtg actaagtaat
    21301 ccaacaattc tttttcatca agcactcgtg cgatacgcac ttttgtaccg acaggatagg
    21361 actccaatgt ttgtcggcgt tcttcatgga caacttcctc ttttttagga atcgatcctc
    21421 catgaggaca atgttcagga tgattcaaat agttttctaa atgatctgca agatgttccg
    21481 aagtcacatg ttccaatact tcagcatcat catggacttc attccagcta tagtctaaat
    21541 gttcaactaa aaaaacttcc cataagcgat gtttgcgaat cagactgcta gctttttgca
    21601 gtccgcttgc agtcaattgt acaccttgat aaggggaatg ttctacaagc tcttctttca
    21661 caagtttaga aatcatttca ctgacagatg cagctgagac atctagacta gatacgattt
    21721 gtttattgtt gactttcgtt gtatctccac ctagttctaa aatgattttc aaataatctt
    21781 ctcgatttgg tgtcatattc gatcatcctt tcatggtaaa aaaccatcat tagtaagtgt
    21841 aacaaaaaaa acgttaattg actatttttc taaataaaaa acaaaggatt tttagacgtt
    21901 tttacaacaa aaaacgaaag atgatagaga agactcattc tttcgtttat aaaggatata
    21961 tatatacatt gggagggatc tatttttcag ataacaactt atatgaagtg tctgcagatt
    22021 cgtcataaag agtttgttcg ggataagaaa agataagata aaaaccatac tgatcacgta
    22081 cgactaaacg atattcatct atttctacca cagatgtgcc aagagactga ccgttgatca
    22141 aaaacgtgta atcagatgta atctgtaatt gttgtttttg ctggctatca ctaaagaacc
    22201 atgtaccttg atactttgag agtccttctg acttttccgc ttgttttttc tttttcaagt
    22261 aaataaaact tgagagaacg gtaatgagtg aaccaagaaa atagatcatt ttttttatca
    22321 ccaaatcact cctttatgag aaaataatcg catagacata ttctttcttc tttatttcat
    22381 tgtaccgaat aaaagctaaa atttctctaa gactttcgac tggttttttt actgtttttc
    22441 tacaaattat gataggatac atagtaggaa gaaaggtgac ataatttgaa gtatcagcaa
    22501 gtggaaatag ctttttttat tgaccgcccg aatcggttta tagcacattg tatgaaaaaa
    22561 gacggagaaa taattattgc gcatgtcaaa aatacaggta gaggaaaaga ggtcctgata
    22621 ccaggcgctg aagtggctat tgtatttgct cctggaccta aacggaaaac cgcctatgat
    22681 ctgattgctg taaaaaagaa gggtgactgg tttaatatcg atagtcaatt gcctaatcgg
    22741 ctggcaattg atggtatttt agacggcacg atccttttac caggattaac tggtccattt
    22801 acggtataca agcgtgaagt aacttatctt cactccaaat ttgatattta tttagagacg
    22861 gtggtcggac aaaaagcatt tgttgaagtc aaaggtatga cacttgaaaa taaagcgatt
    22921 ggtgcttttc ctgatgcgcc cacactcaga ggattgaaac atataggaga attaacgtat
    22981 gccgcacaag atggttatgc cgcttatgtc ttgtttattg ctcagttcga acatcttcat
    23041 ctggcaacga tccatgaaga aatgcaacca gcactagctg atatggttcg acatgcgcag
    23101 caaagcggag ttcaaatcct cgcctataat tgtcaagtat cggcagatga ggtaactgtc
    23161 aagcaggcca ttccatttga tgtagatatc ccttttgaag atcctataca atagaaagaa
    23221 ggtaaaataa tgatcaactt aggtattatc ggaacaaatt ggattactca tcaatttgtc
    23281 caagcagctt taagcacaaa aaaatatgaa ttgacagcgg tatattctag acatttggaa
    23341 aaagcacagg aatttggttc tcattatgaa ggggatatcg aattcgcaac agatttgaag
    23401 acttttttca atattactca tatggacacc atttatattg cttctccgaa tagtcttcac
    23461 tttagtcaag ctaagcaagc aattttggca ggaaaaaatg tgatagttga aaagccagct
    23521 ttttcgacgc caaaagaaat ggatgaaatc atccatttgg caaatgaaca caatgtgtat
    23581 ttttttgaag cagcaagaaa tatccatgaa tcaggtttta aaaagattgc cgattactta
    23641 ccattaaaag acgagataat cggtgcaaat ttcagctata tgaaatattc ttcgcgctat
    23701 gaccaagtat tagatggaga agaaccgaat atcttctcga ctcatttctc aggtggtgca
    23761 ttgatggatt taggtgttta ccttgtatat gcagctgttg cttggtttgg aatgccaaaa
    23821 gaagtccatt atttcccaag aaagatttct actggtgtag atggtcttgg atgggggatc
    23881 ttacgttatg agaattttga tgtatcgatc cagccaggta aaatcggtga ttcttattta
    23941 ccgtcagaga tttattttga ctcaggaacg ctagtgatga atggagtcaa tgcaattgaa
    24001 caagcacaat ttcatgatcg cgcgcataaa gaaatcattg atttggcggt aacagctgca
    24061 gaaaatccaa tggcagatga agcagaggat tttgccaatg tcatggctca tccgaaagat
    24121 ccagcttggg gattgttgta tgaagagtgg atcgagctag ctagaaatgt gaaccaagtg
    24181 atttatgatt taagaaaaaa tggcggcatc aaattcgatg cagataatga ggaagatttt
    24241 taatgaacga atttgtacaa gtatttcccg aaaattggca gaaaaaatat gaggataaag
    24301 ggtttatctc accttctctt attcaacgag cagtttttca gccactaagt aataaacaaa
    24361 gtatagtagc ggtttctcct acaggttcag gtaaaacact ggcttatctt tggcctctac
    24421 tactaaacgt ggaaccaggt gaagcaagtg cgttggtcat ttttgcttct tctcaagaac
    24481 tagctattca agtagcagat gttgcacgtg aatggggaaa agacaaagag ttgaaagtcc
    24541 aatctttggt gggcggagcc aacgtcaaac gtcagattga gggtttgaag gaaaaaccag
    24601 aaatcttgat tggtacacca ggaagaatat tggaattgat gaaagcaaaa aaaataaaag
    24661 cacatcaagt gaaaacaatg gtatttgatg aagcagacca gctatttgac gctgggaaca
    24721 gccaaatcat tgatcaaatt cttcatcaag ctccaacaga gtatcagcta gctttttttt
    24781 cagcgacagc agatcgttcc cttgaaagca ttgaaaaaat cactgggaaa acgtttgaga
    24841 caattgacgt gacagcagag gacgattctc gaaaaggact gagacattac tttttacgtg
    24901 taccgatacg aaagaaagat gactacttga gacgtctcac gcatatagaa gattttcatg
    24961 gtctgatttt ctttaatcaa ctgactgaat taggcgtaat ggaagaaaaa ttgctgtata
    25021 gaggtgtacc ggtaggaagt ctggcctctg atcagaacaa gctactccga aaagcagcgc
    25081 tagaacaatt caaaaagaaa atggtcagag cacttttgac cacagatgtg gcggctagag
    25141 gtttagatat tacaggtctt ccttatgtag tgaatgcaga agttccgtta agtgaagaag
    25201 cttatttgca tcgttcggga agaactggtc gaatgggtaa tgaaggaata gtaattacac
    25261 tcgtacaaga taataatcta agagatttaa aacggctttt acgtccatca aatataacac
    25321 ttgaagagat ttttttatac ggaggtaagc tgcaaactga gcagccaacc aaagaagatg
    25381 cagctcctgc agtaaataaa aagtatgcga aaactttttc tggaaaggag cagaacccag
    25441 aatataacaa agaaaaaata agaaaaaaag ttaaaaataa atcaaaaaaa gagagaaata
    25501 aaggagcaag gcgcaaataa gcgccttttt atgctatgat tatgaaaacg ggaacaaaat
    25561 tggttgccag aggaggggtt atgtgaaaga acgtcaagaa gagatcttgc agctattgac
    25621 agaaaaccaa caaggattga cagcaagtga tgtagctgag cgcttaacta tcgatcgaag
    25681 caatgcaagc cgatatttaa gtgaactata caaggcccat catattgtaa aaaccgctgg
    25741 ccgaccagtc gtttactctt tgccaacgga aaagtcaaaa tctgatgaag tgcatgtcga
    25801 ctcttctacg caagtgactt ttgaaacact cgttggagaa aatgattctt taaaagtcag
    25861 catacagcag gcaaaagctg cgattcttta tccaccgcgg gggttgcata cgattatttt
    25921 tggagaaact ggtacaggga agtcgatgtt tgctgaatgt atgtatcatt ttgcaatcga
    25981 ttcagagatg ctttctgcag atgcgccatt tgtttctttc aattgtgcgg attatgctca
    26041 aaatccgcaa ctgctctttg gacacatctt tgggatcaaa aaaggggctt acacaggagc
    26101 agctcaagat agtcccggtc taatagccaa agcagacggc ggtatattgt ttttagatga
    26161 gatccaccgt ttaccgccgg aagggcagga aatgctgttt actttcattg ataaaggtat
    26221 ttaccgtccg cttggagaaa gtgcacaagt acatgaagca tctgttcaga tcattggggc
    26281 gacgactgaa tcttcagaaa gtttcttatc tacgttcaat cgacggattc ctatggcaat
    26341 caccttgccg aatcttgctt cacgttcact ggatgagcgt tatgaaatca tctctctttt
    26401 tatcaaacaa gaagcgaatc gtttgaatca acgtatcgat atcgaaaaag aagcgattct
    26461 tgccttcatg ctttatgatg cggaaggaaa tatcggtcaa gtgaaacgag acttgaaact
    26521 agtctgtgca aaatcttttt tacattaccg tactcatcat gagaaaaagc taatcattcg
    26581 aaaagaagaa ctttcccttc aagtacaaaa aggattactg aaaatcaagg aaataccgga
    26641 acgtctcgac cgattcatgg acagcaaaag tcagtatttg acatttgaac caggatttgc
    26701 tgatgttgtc tggtcacaag atccagaacg aaacatgcag gtctataacg atattgagga
    26761 aaaagtcact tctctttccg aaaccggtgt ggagaacatt gatctagaga ccctcatttc
    26821 aaaagatgtg gatgcttatt tccagacata tgtcaaagaa ttgactaaaa gttcgattcc
    26881 caaagatctt ttgccagatg aaatctggcg gttaaccaat caattgtatg atgtggctga
    26941 aaaacggtta gaccgtattt ataatgaaaa agctcgtttt gcttttgctt tgcatctgca
    27001 aagtacattg gatcgtgtga gagaaggtca tatgatcgtc cacccagatt tgaataacgt
    27061 acggaaaaat tttaagaggg aattccaggt agcaatcgat ctttcaacga tcattgaaga
    27121 agaagaacaa gttgagattc cttttgatga aatcggcttt attagtatgt ttctttctat
    27181 caatctagga gaaagtgagc ctgttaaaga aaacaaagta gatgttctca tattgatgca
    27241 cggcagacag actgcttcaa gcatgttgga gatggcacaa gaactattag gaacaaaagt
    27301 agggaaagct tttaatatgc cactggttat ggaagttcaa acaatgtatg aagaagtgtt
    27361 acaatatgtc aaaaactatc aagagcattt gacgaatggc ctactcttgt taacagatat
    27421 gggatcatta aacaccttca gtgatttgat ttatgaagag actggcattc ggacgaaagc
    27481 tatcacgatg acaagtacca tgattgtgat agaagcgata cggatggcaa gtgttggaag
    27541 aagcttagaa gatatttatc aaaatatcca gctttccttt gaatcgatcg tacgtgatca
    27601 gttcaaagcg gaaaagtctg aaactttaca gcgtaaaaaa gccgtaatcg tgacatgctt
    27661 tactggtgaa ggagtagctg ccaaattata tcagcgtatt atgccagtga ttaatcaaaa
    27721 taaggtagaa ctgatccaga tgcagttttt agaacgtgaa tcattcaaaa aacacatcga
    27781 tgccttattg gaagaatatg agatcaaagc aattgcggga acagttgatg ttgattatca
    27841 aaatatccca tttttttcag cctatgacgt ttttgatgat gaaaaactaa atattttaaa
    27901 gcgtatagct gatgatgaga tcccgacagc taaaattgtc gattcacttg ctggatcatt
    27961 aagcgatgtc ttttctattg atgaactgat ccgttcattg caaaagacag ttcagcagat
    28021 ccagaccgat ttgtcgatta tcgtggaacc tggagtagat actggaatcg ttatccattt
    28081 agccttcatg ttagacggat tgatcaaaca agaaagccat cggcaatttg agaaactgtc
    28141 tattttctca aaaatttatc gtttggaaat ggatatcgtt cgggcaaact tgatggcact
    28201 agaacgaaaa tatcaggtaa aaattccaga agatgatatc gcatttctta cacaaatgtt
    28261 tcttgaaaat aaaataaaaa aatgaacaca ctaatcatac tgtttacaca ctaaacatct
    28321 gtgtgcgcac tataaaaaag agctaaaaag catgaaaacg ctatttcagc tctttttttt
    28381 attggcatgc ttcttgcgtt atataaaagt gtaaaaaaat aaaaggagtg ttaaaaatgg
    28441 caaaaaaaac aatcatgtta gtttgttcag cagggatgag tacgagttta ttggtcacaa
    28501 aaatgcaaaa agcagcagaa gaaaaaggga tggaagccga tatttttgcg gtctctgcct
    28561 cagatgcaga taataattta gaatctaaga atgtcgatgt attattatta ggtcctcaag
    28621 tacgtttcat gaaagctcaa tttgaacaaa aacttgcgcc taaaggtatt ccattagatg
    28681 tcatcaatat gcaagactat ggcatgatga acggagaaaa agttcttgca caagcagaaa
    28741 atctaatgaa ataaatcaag tatgcagttg ggggtataac aacgtggaag atcaacaaaa
    28801 cctagaagcc atcatggggt taatcatgtt tggcggtaat gcaaagagcg atgcaatgga
    28861 agcgattgcg gctgctaaaa tcggtgattt tgagttagcg gataggaaaa tcgctgatgc
    28921 agaagaatca cttatacaag cgcatcatgc acaaacagac atgttgacac aagaagcaca
    28981 aggaaatcat atgcaagtga cattattgac tgttcacagt caagatcact taatgacatc
    29041 tattgcgttt actgatttag caaaagaaat catcgaactt tatcgtcgcg tatacagcga
    29101 ataaatacaa cttctttttt gaacggaaga agaaaaattt ttgaacggat tttttatttt
    29161 gttataagga gaactctctt tatataaaaa acttatagga ggaagtaaaa aatgaacgga
    29221 ctatcaagtt ggatggagaa atacatcctg ccggttgccg caaaaatcgg agcgcaaaaa
    29281 catttagttg ctttgcgtga tgcttttatc ggcacactgc ccgcaacaat ggcgggatca
    29341 gtcgctgtaa tgatcaatgc aattattcgt gatttaccgc aacagtttaa cagtacctat
    29401 gctgacagtt tagcagcaga caaaggaatc tttgccgtat tgaatgtcat catcggaatc
    29461 aatggttttg tctggaacgg tacactagca atcgccggat tgatctttgc cttttcttgg
    29521 gggtataatc ttgcccgagc ttatggagta aatgatctag ctggggggat cgttggttta
    29581 gctaccttga ttcaaggtat ttcctttggt ccagcattat cagcagcatt agatgtgaat
    29641 gttccttcaa atgtcgcaga tgcaatcaat agttctgaga ttggtgcaac gattgcagat
    29701 ggcacactgt cagttggatt atggggttgg ctaaaactag atcatttgaa tggaaacgct
    29761 tattttacag ttatgatcat gggagctatt tcagtcatta ttttttgtaa attgatgctt
    29821 gccaacatta cgatcaaaat gcctgattca gtaccaccag cagtatctaa agcatttgca
    29881 gccattttac cagcgacgat cgctttatac gtcattgcta ttatcaatta tatcgtaggt
    29941 cgtgtagctg atgggcaact gatcattgat ttggtgcaaa aatatattgc agaaccattc
    30001 ctaggattat ctcaagggtt gggagcagta ttgatcgtca cagtatttgt tcaagtattc
    30061 tggttctttg gtattcatgg accaaatgta ttggcaccag tgctagaggg aatctgggga
    30121 caagcacaac taatcaatat tgatattttc caaaaaggtt ataacggaaa aactggtaca
    30181 ccagccgtgt tagatgcaat cgaagatgga aaagcttata tgtgggtccg cggatcgttc
    30241 gatgcttttg catggtttgg cggatcaggc ggaacgatcg tcttactgat agctatcttg
    30301 attttctcta aacgtgcaga ttatctaaca gtagctaaat tatccattgg gcctggtatc
    30361 ttcaatatca acgaaccagt gatgtttggt ctgccaatcg tattgaatgc aatcatgttt
    30421 atcccattct tgattgctcc agtagtagca acagcaattg gatggacagc tacttatctt
    30481 ggcctagtcg ctccggtatc gcagcaagtc acatgggtag taccgccgtt cttattgtca
    30541 ttcttagcaa caggagcgga ttggcgggca ccgatcgtaa cattagtatg tatggtcgtg
    30601 actttcttga tttgggcacc atttgtcatc tctgcaaaca aaatggaccc tgccgcaggc
    30661 gaacaacaat aagatgaacg tgaggagcgg gacgctttaa gtttcgttcc tcataatgaa
    30721 ttttcgagga ggaactgaaa tgattacaat tgccagtgca atgcaacaag atgaaatcaa
    30781 agaattgtta gaaggataca atgaagaagg aatgactttt acatttaaag aaaaacaagg
    30841 aatcaagctg ttctttgaaa caagtgcaga agatccggaa gttgcggcta aaaaagcaaa
    30901 ggaactaatc aaagcacagc cttggggaac agtcctttat tttcaatcaa cagctgttta
    30961 gaaaatggtt taaaaagata ggatggttga gatgataaaa aacggtttat ttttatgtag
    31021 tattggttct ttgatcgtgt tgtatagttt gaatccacat tcgcaaaggt atgatttgta
    31081 tagtatggtc acaggtcttt ttctaacagg attaggaatc tatttcttca tgaaggggaa
    31141 aaaaagagaa gaagcaaagg agaaaaataa ctaatggaaa tcacgaaaaa attaaatatt
    31201 ccagcatcgt ttttttacga taaagttatg gactctgtcc ttttcgatgt acgtaaagcg
    31261 accggcaaat cagtaactag aaaacagctg aaaaatttgg agtacgtcaa acaattctcg
    31321 caaaataacc gggctcgcat aaaaatcgaa gaagtcattg aaaaccagtc ttataagttt
    31381 cgtacatcga caacgaagaa tgaattcgtc gttcattatc aaatcaaacc attggacgat
    31441 tcgacctgtg aggttcatta cacagaaaaa atggagtctt atggcatgct tcaaaagttg
    31501 aatgatatgc ttttaggaac aatcttgatg tattttaaac ggagacgttt caaaaaaatg
    31561 ctagatatga tcgaagcaac gtattaaatc aatgaaacat ggtactattt agttattgaa
    31621 aaatgaagta agctagaagg aatttttcat aggaagatag atctttcctg cgaatcctca
    31681 ctagcttttt tgtaggaagg ggcagcaaaa tgacaaacaa agtaagagag ctaggtgtat
    31741 cttcgattga ggaaatgttt gatttagcca cttatgcatt taatggggca gatacacctg
    31801 aaaggcgaga acgttttcgt acacttgcgg agaattcttg gaattacgga ttttttgatg
    31861 aggaggatcg gctaacaagt caagtcatgg cgaccccttt tccagtgaat ttttacggac
    31921 aagagtacct aatggccggc attggctatg ttgcttctta tccagaagca aggggacaag
    31981 gcgggatcaa tcagatcatg gaaaagatcc ttgaagattg ccgtgatcgt aaagtaagct
    32041 tatcttatct ggcgccattc tcctatccct tctatcggcg ctatggctat gaacaatcat
    32101 ttgataaaat cagttatcaa ctaaacagtc gtgatgtgcc gtttatcaaa aaaaaatctg
    32161 gaaaaataaa gcgtatggat tttgaagatg caaaagctgc aatcagaaga atttatgaac
    32221 agatgccgga aaaccaacga gctggtctga agcgcgaaga ctggtggtat acgtataaat
    32281 tcaagcaaaa aggcaattac cagtttgctt tgcattttga tgataatgag gaagcaacgg
    32341 gatatatcgt ttatcagctt gcaacgtctt cctttattat tgcggagtgg ggatttttgg
    32401 atcatgatgc tttttgcagc cttgttcgct tcgtaagttc tcacaatggt gcttttgaaa
    32461 catttgaata ttcatgcggc tacggcggta atgatcaaaa ttatctatta gaaaatccat
    32521 ttgcttctgt aatgatcaca ccttatatga tggcgaggat cgtagatatt tctttgtttt
    32581 tggaaaatta tccatttaaa aagagacaag ctgcatttgc cctacaaata gaagaagatc
    32641 attatgcgaa atggaatgaa ggaatcgtgg aagtaacaat cgaaaatgga aaaaatcatc
    32701 tctcaaaagt agaacaaaca aaactcccaa tcgttcgagg aagtatccaa catatcacgc
    32761 agctattatt agggtatcgt aaagtggaag agttggtatt ccaagaaaga atacaggtga
    32821 caaaagaata tgaagaaacg ttaagctcaa tcttgccaca gcaacagcca attcttaatg
    32881 actatttttg ataaaaaacg ggtgatgaca atatttttgt caccaccctt ttgtttttca
    32941 tttggcattt gaaggaaaat gttaaagtaa atcctctttt ttcgtaaatt tgaatttttt
    33001 gttttctttt gttttagggt tttctttttt gtggtcttgg attgcttctt tcgtaatctt
    33061 ttcccgattt tttttagatg aatctaagcg ttctgcgtat actttttctt ttggcttatc
    33121 attcattgga aaggacctcc ctacattatt tcattctacc tctagtttat catctgttaa
    33181 ggactagtgg aaacgttttg cctaacttat aagctgattt ttttagcaga taagcttgca
    33241 agtaaaaaac aaacaagcta caattgattt attgaaattg ttcctgtagc tcagtaggat
    33301 agagcaatcg cctcctaagc gataggtcgc tggttcaatt ccagtcagga acgtataaat
    33361 aacccctgta tcctttgcgg tacaggggtt tgttttgtat ttgtgccaaa aatgtgccaa
    33421 actagttatc atttttatat aaactatcga acacagtatt gattttttct ttatcctgat
    33481 cttcaagctc tcgaacaata tgaagataag tagacattgt agtttctaaa ctgctatgtc
    33541 ctaaacgttt cgatacgcta agtatattta ctccttgata aagtaaaata gatgcatgtg
    33601 tatgccttag tccatgcaaa gtaaattgct tttcaatccc taattctttt aattttttgc
    33661 gcaaatattt gctgacggcg tttgatgaaa ctaatccatt ttttaagttg aaaaaaacaa
    33721 aattatgagg gtttttgatt tcaaaattct cgaataattc tttttgattg attttaaact
    33781 tttttaagag atcaatcgta tgtttatcaa tggaaatttt cctatttgaa gtttcgtttt
    33841 ttgtttttcc ccattcattt aatttataat tccatgtttt attaatagtg atgatttgat
    33901 cttcgaaatc gatatcttcc catgttaatc ctagaagttc agcaaatcgc attccagtgg
    33961 caccagcaac taacacgagc ataggagaag agtactgcgc agaaaggttt tcttctacga
    34021 gtttcattaa agatttaaat tgatcataat ctaaatattt atcttctttt ggcttcaatg
    34081 aatcttttcc tttgattact gcttttctag ttggatcaaa cggaattaat ccttcttcta
    34141 cggcatcttt caacgacgct ctaatatggt tattaaactt aataacggta gattttacat
    34201 ggtctttagc atacttattt aaaaagcgtt gatatcccac tctatctaaa tcagaaatca
    34261 ataccgctgg catatatttc tttatgttca ttaacgtatc ttcgtatttt ctataagtga
    34321 taggagatac tgttccttct ttataaagtt gcatccaatc ctcaaagtaa tctgataata
    34381 atagattttt gcgatcccct ttaaggcctt tgttcaagtt atattctaat tcgttggcgg
    34441 catcttttgc ttctcctttt gtcttaaatc ctgattttct tatcttcgtg tattttccgt
    34501 catctttttt gtatgaaatt tcgtattgcc aactatttcc acgtttgact aatcttgcca
    34561 taattgaatc agctctcttt ctctgataca ataggaacta taaagaagcc cattgtttgg
    34621 gttttattat tttttgcaca tcctttttgc ttgccggcgc aaggatgtgc tatttgtcgt
    34681 tttaatggta taattggatg tgtattagat catccaatca gaggtgttta ttatgattaa
    34741 agtgattttt aaaagaataa ctgaacttcc agagtttaga ttatttgttg attattggta
    34801 tgtctggttt tttattgttg cattgctgat aggtctagat gtcatattag aaagaaaact
    34861 taagtaagag ttgagttaat aaattgaatt cctaaatgag atattttgta gcccatattt
    34921 tgtttgccga catcacctaa tactatggag ctaatcgttt tttctaacag accaaaatca
    34981 gataatctat ttaagctacc atctattagc tcttgtgaat agccagacat gctgatattt
    35041 ccagtgaaat tttcgtttcc acgactcatt aagcatgcta acaattgaat ctcaatcgat
    35101 gttaattgat tcagtacaag aagataatac tcctcgttat cccatgaagc gttgttaatt
    35161 cgaagtaaac aattcttata aagattttta tacatatcta ttttattttg tgcctttgat
    35221 ttttctacct cgtcatttat cccttcgaat attccaatga gttggtcctt gttctctaag
    35281 ttgaaaacat cttctggaat ttgatcgcga atgttttcta atgattcgtt taaatttttg
    35341 tagaatttct cgatgcgttt gaaacgcttc tcgtttttag acccaaaaat aaagtgactg
    35401 cacaacgcca ccaatataag gaattgctcc aataccgcct tcaactatta attcaagata
    35461 ttcttttttg gttagttttt cattgctatt atccatagtt acctcctatt ttgtcatttc
    35521 ctttacaagc attgtgactc ctgatggcac tcttttgtat aggttttatt attgtgcaca
    35581 atctaactct tagtggggcg tggttcattt attttttact tactttacta ttaatcatat
    35641 cccattgagc ataggatttt tctatgttcg atcctcttga actaatttct cctgtaaaag
    35701 ttactttatc gccctttgta aaggtatcag cattgtttaa gtccttcgca aaaattacat
    35761 atgaaacttt aggtgttgca gaaatatcat tccaactttt atcatcgtac tctttgtctg
    35821 ctataatggc tattctagta gtcattgatt cgataacagt tccttcaaaa gtatatgttt
    35881 taccactaat atatttagta aaagctgtat tttgctcagt agctggagta atagaataat
    35941 aactatctaa gaaagcaccc cagtcatgat tatttgtctc taaaaattct tcaaattgag
    36001 ttaggctttt attgctgctg ttagatgtag tagtttgagt atcagatgat gagctttcct
    36061 gtttgttatt gtcatttgcc tcgtttgatg aggaaagcga gaaacctacg gtagtaaaaa
    36121 taatcccgat aataaggaga atcataggtg ttttcttatt tgtttttttg ataaatctta
    36181 caattaacat gattaaacct ataataaata aaacaatacc agtaaaacca aatataccgt
    36241 ccattaatag atcctctttc tcttttgata ttgaatatta taaaccaagc aattcttttt
    36301 tcttaaaatc gaattcttct tgattaataa tcccttcatc taacaactct ttatactttt
    36361 taatttcatc tgcacttgaa atttgtgttt ctttggaatt attatctaat atagattgtt
    36421 gcttctctat atattttttt aaattttcca tttcattcca atattttttt gtaaacataa
    36481 cggtgttttc atctttcgtg gccgctaata tacctccgcg actttcgttt ccgcctagca
    36541 aggtaaattg tatataacca ttactcatac ctggtttttt taattgtacg gctgatatat
    36601 ttttaaaggg gatagttttt tctcctttaa taccttgatt aactaaattt ataaatcctt
    36661 ttctaataat tgaaatagaa tcatcagtta ctttaatcaa ggtttttcct ggagatttta
    36721 ttaaaatctc tttttccatt ttttcttcct catttctgtg atatgatttt ttttgtagaa
    36781 gctcatatat gaggaaagag cccgtgttgc agcacgggct tttttaatgt tttgctgaaa
    36841 tcggtttttt taataattct tgatgtattc atacatattg ccttgcgtaa gaatattttt
    36901 tcttaaaata gcattggcag acagcataac aagtgtatct gagcttattc tgaatagaat
    36961 aatactccat aaatttttcg agattaaact gagatttatc agtcagttcg ttctcaatat
    37021 agatatttaa taaaattaga atagctattt tatctgcttc tgtttcaaat tttgagtgaa
    37081 aagttgtaga agtatcgtac aaaactgaaa attcaaaatg agaggcgctg aaatgtgcaa
    37141 gttcatgaga taaatgaaag gcttctgcag tttcaccgta tagattttca ttcaaaaaaa
    37201 tgattctggg ttttggatag tagaaaccag gctctttcat ctccatataa actactttca
    37261 aattgtattc gctcaacatt tctttcaatt tcaaatacat acaaaccatc actccaacta
    37321 ttcattttcc tctaaagctt tagcaattgc aatcgcttta cgcattgtct ccttagatat
    37381 ttcttttcca tcaaaagaaa aaacagtatc gtcttctgat aaatccacat gtttaggggt
    37441 ttctctttct tctctaccta gaaggtagtc tacagagaca tcgaaatagt cagcaatccg
    37501 acttaattca tctgaattag gagtattatt tttccacttt gctagataac cgttagaata
    37561 tccaaaatta atttctaact gccgtataga tatctttttc ctcttcgcca agtcttttat
    37621 tatttcatag gtattcatcg ataaaacaac ctttctaaat gtttacaaaa aaagtttaga
    37681 aaaatacgca gaaataattt gactaattct gagtaatgag ctatactata tcttgtaaac
    37741 agatttaaca actaaaaaga caacaaaaaa cactattgat atgtaaatgc agaccgccaa
    37801 gaaagcttta aaatcaatgt ttttatgtct tatttaatta tgctcttagt atagagtatt
    37861 actcagatac tgtcaattga atttagaaaa aagttgttaa atttgtttac gaatataaaa
    37921 gaaaggaatg agaaatatga acacaccgca aatttttaat ttcgaacaaa acgaagttcg
    37981 gacaatttta gtaaatgatg aaccatattt tgtaggcaaa gacgttgcga gtgttttggg
    38041 ttattcaaac actaaagatg ctttgtcgcg gcatgtagat ttggaagata agatggggtc
    38101 gcgaatcacg acctcaggtc aatcaagaga gatgacaatc atcaacgaat ctggtttgta
    38161 cagtttaatc ttaaaatcaa aacttccctc tgccaaaaaa tttaaacgtt gggtaacaag
    38221 tgaagtgttg ccagcaatta gaaaacatgg aggttatcta actccagaaa aagtagaaga
    38281 agctttgctt aatccagata caatcattca attagcaact caactaaaag aagaaagaac
    38341 tggaagatta atcgcagaac aaaagattgc agagtacgaa cctaaaatct cctatttaga
    38401 tagcatatta tcttctacag attcagtaac aattagtcag attgcagcag attatgggat
    38461 gtctccacaa cagatgaata aattacttca taaactaggt attcagaaaa aagtcggtaa
    38521 ccaatggtta ttgtgcaaaa aacacatgaa ccaaggatac acaaaatctc atacaactga
    38581 gatcccgaaa gccgatggtg gcactaaaat tgtaatgaat accaaatgga cacagaaagg
    38641 gcgtctattt atctacgaat tactaaaaaa agaaggatat taccctcaaa tggatttaga
    38701 ggaaattggt tagaaaggag ttttagtatg actgacattg cagaaatcac tcaacgagat
    38761 agagaaaaaa tcaaagaata tgtcgaaagt tcaaagttct taacttacac catgcttgct
    38821 gaaagatttg gaattagcaa aagctactta tctttaattt taaacggtaa aaagacttct
    38881 gcagaagcaa acagaattat agattcgatt atcactatgt acgaattgta aagggaggaa
    38941 cagctaatgc aatatctaga agcaaaaatc ccaattccag aaggctatgt aattatctcc
    39001 caagtggatt atgaggagtt aaaaaaagct gatgatactg gtagatggat gacgttgcca
    39061 gaagtgctag aacggattaa cagaaaatat gattggttta cttctagagt tttaaagaac
    39121 ccaagatata gaaatattat cgatatcgag aaaaacaaaa atggatttgt ctattatcca
    39181 gttgaaggaa gagacacata tctattttta agaagtaaaa cacttgaatt tttagaaaca
    39241 aatttttcgg aaatcttaag gaggcaagcg gatgggaaaa tttaatagag cgctagtgtt
    39301 cagcgcaccg ctaatcatct acgctttagg actttgggga agcaggcaag cgttgatagg
    39361 aacgattgtt tacatggttt ggatttttat ggggcttgat gaagctgaag ctgagtacag
    39421 agcgaaaaag ccaaccgagg gggctgacta aaaatgaata gaaaagagaa actagaatgt
    39481 atattactat tactcagttt aattctttca ctaatttctc tattgggaag tttgtatttt
    39541 tgatatcaac aattttgtgg atttgggttc tatttagagt aaatatcatt tttgtttggt
    39601 gattaaggag tttattaaaa ttaattttcc ctacttcaaa tgcaaggtaa caagatatag
    39661 cacttttagg aggaatattt agcggtacag cttcagagta tattctatta tcatcgactg
    39721 atcctccttt agcaattaat ttcttaaatg gagtagctga ccatctgcgg tttaagttag
    39781 cggatgaaag ttctaaatta actaacatag ctggttctgt tgaatagtta gaaatgatta
    39841 cttttgtata aatcatatct gcagcgaagt aagaagcatt aagttcaact tctagttgag
    39901 ggcgcattcc ttttattttt atccctgtta aaaacgtact caatataaaa cttattattg
    39961 acatccattg aaaaattgtt aagtgaaaaa aattcaaaat aaacaccacc agtttttaac
    40021 taaattatac caaaaaggag agaagaaata atgcaagaat tagtaatttt gaaaaataaa
    40081 gaagctgtga ctacgagctt acaagtggca gaaagcttcg agaaaaaaca tcaacatgtt
    40141 ttaagagata ttgatgcact aaaaaaagat gtgtccaatt ttggacagat gtttgtagaa
    40201 ggtaatgaac cagattcata tggcagaaat cgacgagttt tcttcattag tagagatgga
    40261 tttttcttgc tggctatggg gtttacagga aagaaagcta tctacttcaa acaaaaatac
    40321 attgaagcat tcaacgaaat ggaagatgtt attcgcaaga atactgttcc tcaaacaatt
    40381 gaagatatga tgatctatca attagaagaa atgaaagatg ttaaaaaaga tgtttccatg
    40441 cttaaagata ctatgcgaat tagcggacaa caagagtttg aaattaagca aaaaggaaat
    40501 atgaaagtta tgggagttct agggggaaaa gaaagccgag cttatgaaga aatcagcaaa
    40561 aaagtattct caaaattttg gtctgaattt aaacgtacct tttcaatccc aagatatggc
    40621 gagttacctc gtaagagatt cgatgatgct gtttcattta ttgaaatgtg gttgccagaa
    40681 actgcgatcc gtatggaaat tgatcaactg aacagacaac agagactttt tggtgatgac
    40741 aatgaataga gctgaagcgc taagaatagg gacggcaatt gctaattgct ggtggaaata
    40801 ctataaacca atcatcctaa gccaacaaca tattgacaag caaaaagcat ggcaacaaat
    40861 aaaaaagtga ctccgccggc aagcaaagag tcacaaagaa aacacatcat aaggagattt
    40921 tagcatatgg aaaaagaact ttccactcta gatcaatatt tgattgatcc tgattggggc
    40981 aagccgaaaa ttgaggaaac aagtggtcga aaaatcagac gaaatctttt gacgaatgaa
    41041 gaactagctt gggatcaaga tgatttaggc aaccatgtaa ctatttggga tcatgtttat
    41101 cttatccatc tatcgaagca ttcgaataaa cctgaatata tttacgtcat cgaagatggc
    41161 ttgattgatg cgctagaaga gtacgacaga gataacttga ttgatatctc ttattacgga
    41221 ccaggtaaga aatacattgc tgaaatggag gcagaatttg atgagtgaaa tcaaagggac
    41281 aacgaacttt gaaaaacttt ttagtcgtaa gttaaataaa attctcaaga aaaaaggaaa
    41341 ttttgattat ttatcttggg ctcacgcgtg ggagattatg aaaaagaatg atccacaggc
    41401 aacggtaact attaatgagt acaaacacta cagggttgtt tctggaactc atcaagactt
    41461 tcttgttgag gaatataaac cttttcttat ggatgaaact gggacttatg tatctgtctc
    41521 agtaacggtt aaaggacaca cggaaaccga attatttcct gttttagatt atcgaaacca
    41581 accagttgtt aaaccaaatg caatgcaaat caataactca ttgaagcgat gctttgtgaa
    41641 agcattggct ctacacggac tgggattata tgtatttcaa ggggaagata ttccaacacc
    41701 acctagaatc gatacaaaga aattaaacat gctagagacg attctagaag ctttcaatga
    41761 gcagatgggt aaagatatga ccaaaacctt aatcgaatat gttaatgagc agacagataa
    41821 attagggctc ttagctgata acgttgaaac tattgaacag ttaagctatg agcaatgtgc
    41881 cttgatggag cgagcaatag cagctaagag aaaagaatta gataagaagt gatatgagtg
    41941 tttaaaccat taatcgattc atattcagcg gttctgaaaa agttcaaagg aaaagacata
    42001 agcgcaacca tcaatgagga agtgaacatt gatcgactaa agacgatgta tgacggctac
    42061 gatggtgatc gagtcattga aattcgtttt attgatccta gacgtttcac cgtacagcaa
    42121 cgaaacttca tctatgcgct gataggcgat atttttatcg atacaggcat gccaacggac
    42181 ttctggaagg aattcttcta ctttcgtttt gaaggtgtca cagggcgcaa aataagcctg
    42241 aaagacgaat cgaatacaac tgtgagtgat gccaatgtct tagcaaatat catcttagat
    42301 ttcatctttg aacatcatat tcctttcaaa gaaggctatg agattttacc tgcgaatcaa
    42361 gaatattact tctacaaatg catcacaaaa agagtctgct gcatctgtgg caaaacagga
    42421 gctgacatcg atcactttga caaagcgcta ggaagacgaa agcgcaaaga agttgatcat
    42481 gcagagtaca catttgcagc actctgcaga atccatcaca cagagaagca caaaataggt
    42541 gtgattaatt tcaaaaataa atatcaaatc aaagggatca aattaaacca gaaaacaatc
    42601 aaaaagttaa atattggagg gtaaaaatga cagaacatcg aagttattat gcgattatac
    42661 cagccaacgt aaggtacgac aaaagactta aaccaaatac taagttgtta tacggagaga
    42721 taacggcctt gtgtaatgaa agaggctttt gttgggcagg caatgagtac tttgcagatt
    42781 tatatggtgt gaataaagag accatatcgc gatgggtaag tgatttgatt aagtttggat
    42841 acttgaatcg ggaaatcatt tacaaagagg gtaccaatca aataatcaat aggtacctac
    42901 gaattaatca ataccctatt gacgaaaaac gcaatacccc tattgacgaa aaagtcaaag
    42961 ataataatac atctattaat aatacattta ataatacaaa agaatatata agagagttac
    43021 cgccttcgaa aaaatcgaag gctaagcccg tccgtcataa atacggagag tataaaaatg
    43081 ttcttttgtc agatgagcag atggagaaac tcaaaacaga attccctaat gattaccaag
    43141 agcgaatcga acgactgtca gagtattgtg aatcatctgg taagacttat aaaaactatt
    43201 tggcaactat tcgaagttgg gcaaggaaag aaaaaagtga acctaagaac gcaagcagtg
    43261 gatacaagcg cacaggaaga cgagagaagc ttcctgaatg ggcaatcgac caagaagcct
    43321 atctcaagaa aaaagcgcta gaacgagcta atagacaatc aaaagcacca ttctaagagg
    43381 tggaaaaatg aagatcgatt atctagaact aattaatgaa atagcgaatt ataaaaaggg
    43441 cgaggaatta gacgtcctga gagacgtata tgatcaactc gaagaagctg gaattgaagg
    43501 aattaagaat gatcgttcga gttggagtaa gctcagatac tatttcgcac tttatatcga
    43561 tacaacacaa ttaagaaatt tagcatatac caaattacta tttgttgatt gtgttaaagg
    43621 cttgcaaaaa catcttaatg aacttgagca ggtgtaatca gatggaccta aagacattta
    43681 cagcacagat tgaactaatg catcaagaag ctttaagaca aagtgtatcg tacgaagaca
    43741 agtggctcaa cacgttccat ggcggacgtg agagcgcact tgatcaagta ctcaaattac
    43801 tgaaaggaga atgtcgggat ggataagaaa gcggcaatgc agcgaattat cgaattgact
    43861 tattcagaag attggcaaaa tgacaaagaa gctgcttcag aagtgatgag gcttggaaga
    43921 gcgatgtggg cagacaagag caacaagcca agaccacgaa aaatcgcaat ttggcacggt
    43981 gacaaacttc tagtgatagg gacagctgaa cagttagcaa gtctcacagg cttgcacgag
    44041 aaaatcgtga ggaaaagagc aaggtgtggc tacacagacg ctaagaagag aacgtttaga
    44101 tacgtggagg aatcatcatg acaacagaag aagtgattca aatgcgtatt cgaagccttc
    44161 agcgtgagat tgacgatctg gaacgaacaa aggcagtgat ggtcaatgaa acggcgagaa
    44221 aggcaatcga tttgcacata gagaatttaa gaagggaaat ccatcgattg gaggaatgag
    44281 cgtggataag aaagcagcaa tgaaaagaat tgctgaatta accaagtcag aatcttggca
    44341 agaagacaaa gaaatagttg cagaagtcca aaagctcggt aaatcaatgt ggactgaaaa
    44401 gcccaaacgg agaacgccga gaaaaattgc aatctggcat gatgaccgaa ttttagtaac
    44461 aggtactgct gaacagttat ctgaaattac tggattaagc aaaaacatta tctgggatag
    44521 agctaggagc ttatggattg attcaaaagg acgacagttt aggtatgtgg aggagagata
    44581 atggatctca ttacacaata cagtgacatc atcctcaaga aaatcatgat gaagattcag
    44641 aaagataaaa aatcaaaaga acgagctgaa ttagttaagt tagaaatggc tgaaacagga
    44701 gcaggagtgc gaagtagcag gcattggaaa gcagcagcaa acattgaatt ttattacaac
    44761 gaaattcaaa aagggttcga tcagatgcgt gagctggatc ggcaaacaaa ttggagcaag
    44821 aaacttcatc aagatcgttt caaatttgta gagaagtata aagaaatatt agaagagtat
    44881 ttgaggagga cagcaaatga taaaaaaact cgttcaattc agcatggatt tatatgatat
    44941 cgaatcagga gcaacactat ctgtggaatc ggaccatcta atcataaatt ttggtggaaa
    45001 gcgccagatt attttgtggg tagttgatga tgtactgttt ccagaaattg ttcatgattt
    45061 cgaagaatca aaagcggttg agtttgaaat agtgaaaaaa gtaatggaat tgattgaaaa
    45121 atacgaggag gacagcgaat gataccgaag tttagagcgt gggataaacg aaagaacgta
    45181 atgagagatg tagccgtctt gcattttact aaaaacggca aaacaaactt tattgaatat
    45241 tggataaatc ctaccgaatt gaaatcatat cacgtgcgaa acatcgacct catgcaatcc
    45301 acaggaatga aagataagaa tggtgtggat atatttgaag gggatatagt attagtcagc
    45361 gtgcgaaatg gcttcgatta cttagataat aaagtctgta ttgtcaaaaa ttcaatagat
    45421 tattccggat tagtttgtgc cactgttgat gaagacttag agtatcaaat ttttaacaca
    45481 gagctgtttg aagaatacac gtacgaagtc accggaaata tatacgagaa tagcgagtta
    45541 ttggaggaac agcgatgaat aaacaggaag caatcaaaaa gttagaaagt attaaagcga
    45601 taggaaatga tgcaatagct gcttgctata acgagagtat aaattcaggt attacgttaa
    45661 tgaaaaaaat agacgaaccg cagaaaccag ttattccaca actcgtggcc ggttggcttg
    45721 agaaatctac ggaccctttt acaaaagctg aaaaaatagc gtatttaatc aaatctaaag
    45781 atggtgattc atattatttc tgtgattggt ttgtacgaga tggcatagtg acgcaagagc
    45841 aaggagaaga attactcgct tgggcaacaa gacaatcata tgaaacacta ttgagcctat
    45901 acaacggcta cgaggttgag aaagagccgt tatgggcaat aaagaatgcc gatggaaact
    45961 atcttactaa atgtgcttta tggggaaaag atggagtaaa ttatagtttt gaatgcaatc
    46021 catctcatcg attgcttttc actgataaag caacagcgga tgctgcagca ttgttggtga
    46081 atggaacagt ggaagaggtg gtagaaagat gaaactaaaa gacggatttt acgctagcag
    46141 tcacggtatc ggcggtttaa tgctagatat gccgacaaag aaccctaaaa cacgcaagaa
    46201 atcaaaattc aaagtcggtg acatggtccg ctgtgaagca gaagagttcg tttatccgtt
    46261 cagaggatac gttaaaaaga tactgtcaaa ctcagcaatc attcgtattg aaaatacaat
    46321 gaagtgtgat cgttcgactg caaaacacaa gcattattta gctgtagcga gattagttga
    46381 catggaagta atcaagagca aataaaaaaa gccggatcgc tccgactgat tcaataaatc
    46441 caacacattt attatatcac ataaaggagc ggtttgactt gatgcaattg ttacgagagg
    46501 tagatttcaa acagacaaga tgtaatgcga gagatgtgct gaagaacttt cggcgtttgg
    46561 agcggatggc aggtcgctct ttgatagata ttaagtcgcc gattataacg gatatgccga
    46621 aggcaccgaa gcatggcaat aaggcagaag acgcgattat tcagatgatg gatatagaaa
    46681 cggagagaga tgcgattcta gcggctttga tggctcttag tctgattagt cgtcagatac
    46741 tctactacag cttctgtgtg ccagatagct tctcaaacta cagaattagc cgtgaagtgg
    46801 gttattcaga aagaagtata caacggatga agtcggaagc tctaatagag tttgcagaag
    46861 catataaaca cggaaaaata attgcttata aataatttgg cggttttttg gcggaatgat
    46921 ggcggttttt agacatttac cagtgttatt atggtagtgt cgaaagatta ggaaacagga
    46981 tcgacaaaat aaacgaaggg aggcaatctc cctcatcgtt ttaaacttct tcttagatag
    47041 acagcaacta attatgaaga aaaggatgtg aattcaactc ctcctaaatt cttcatcggt
    47101 tgctgtttat tttgattaga cagcagcact cacaaaacta aacatgttct tgtcgtcttt
    47161 caactgctgc tgtctattaa tttatgtatt ggagggaaga aaaatgaaat tatcagtaga
    47221 aggcactcca gaagaaatac aagaattgct ccaagctatt ggtagtagca aggagcaaaa
    47281 ggtaagtgtt tctaattcag atattgacgg tatttgcaat tgtttaaaca gagaaaaaat
    47341 atctaatcct tactaagaga aaatatgttc gttaatgaat ttccaatttt cctctgtagc
    47401 tctaccttga taattttttt gcagttcaca gatgaataag gaatcgttat tatcaagtac
    47461 tgtatttaat ttttcacaca tttgatttgg attcaaatta gttttaacta accaaaaaga
    47521 tttttgtagc tttatatatg ccccaaattc ttttattatt tcaaatactt tatcatactt
    47581 ttgccctggg ttattaagat cataactaat catgtagggt ttatacatgt tgtcttgcac
    47641 atccttgttt tatatttcag cggaccactc gctgataaat aaaattatac gcttagtatt
    47701 tattttcaca atattaattt atcgtaataa cttttgagta aatagaacaa aaaacctgca
    47761 ctagtttccg ctagtacagg cagtgactat atcggttgat aatctagcat atattaaaaa
    47821 taattgcaag aaaagaaatt tatagtggtt tataccaaat tatcaaagca atgttatttt
    47881 gttgctgtct attgtttttt aattattcac acgataacta aaggtgggtg aagagaaatg
    47941 attccattaa taatttcaat ttttgcgctc tgtcttaatg tctatatgat tggatttaaa
    48001 aatgggcaaa ataaaaaata gtagcagcca agaataattt tatagtgtca ctgtggcgga
    48061 aagggtagac gctaagcatg tgtgctaggt caatgcttcg gcaaccatgc aaggttcgat
    48121 tccttgccag cgacattaaa tgcctatgac ggttacgact accgaaaaaa gatcgttaag
    48181 aagctatacg gtgctacgta cggcaatgta gtaagtgtgc tatctgtaca ccaccaagct
    48241 tcggtcactg tggcggaagt agaagacgca gcggtaaatg gcgagtagcc tcgtgagagc
    48301 ctggtaagtt ctcgtgagtg gtgcaatccc actccagcga ctttaagcaa ccgaggcatc
    48361 ggcggtttaa aaatataggg gtgcgcaatt tcgtacgcgt tttgtgcatc gtgcaagtta
    48421 ctattacata ttagatcact ctttgagtgg tctttttatt tttgcacaaa ggaggaaaca
    48481 acaatgtata gaccacaata cttagaacag aagtatgaag taatcactgt tcataaaggt
    48541 aatggcgaaa aagtatatga gtatagaaga ccaataaaga gcgatacata taaacgaaag
    48601 gaaaacaatg aagttattcc attgtatggc aaaagaatag ctaagcatta aataagattg
    48661 cgaaaggaga cggaacatga ccgaggaatt ctatagatgg ctattacagt tgacaagaga
    48721 agatcgtttg gttaagttct atcagtctcc taaatggcgc aggcttagag agaaagcgat
    48781 gaaacgagat cactatgaat gccaagagtg tagaagacta ggtaagtatc atagagtaga
    48841 gaacgttcat catataaagg aagtcaagga tagacctgac ttagctttag atttagataa
    48901 tcttatttgt ttatgtgttg aacatcataa tgaagttcat ggcagatatc ttacagcatt
    48961 agataaacaa gagaagaaga tagaaagctt tgctaacttc gatgcaagtg aaaggtggta
    49021 agtgcatgat catcaatgat aatggcagag agtatgatac agaaaagatt gaagagtatt
    49081 catcttatac tcagggatta attaaacgtt tgatatacgt tcgctatgta ggtattaggg
    49141 atctgttatc agataactgt tgtagtaaat acaaagtgaa tcaagtaaga gaagcgttga
    49201 ataaagataa taacgtcgaa agaataaaaa atgtttttgg atatagtatt gaagagatta
    49261 attattacat tgacttcgct gaagctttca ttccgatggt gagataaccc ccccttaaaa
    49321 taaatcgcaa attttttggg ggtgatgaaa cggagggggc tgtcaggaaa agagattttt
    49381 tcgaacttta tcatgaaagg agggctaaaa tgtttaaaaa cgaattgtct caaaatcgct
    49441 acagagaaaa attacgccgc tctttaataa gccaattgga aagtcagaaa acaaatattg
    49501 agccattctt agataatgtt gatcgttata tcagtttatg ggaaacggcg atatcactgg
    49561 aagaagatat atccgagaac ggcattagac tggagaatgg taaaaagaat gaatcagtag
    49621 cgttgcttgt ttctgtcaac aaacaaatgg gattgatgtt ggataaactt gccattactc
    49681 ctgaattggt aggtgaagca aatgaatcaa ttcctgagtt ataagcatat tgaaaattgg
    49741 ttcaaagcta tagaagaagg cactatcaag gtatgcaaag agcaattatt gctaaaaaat
    49801 tatctagaag aaagagtctt tactagagaa gatatttact tcgataagca gatggtagag
    49861 gattcaatca atataccagc acaatacttt ccattcgaat taattccgtg ggaaaaattt
    49921 ctacaatgtt ttatttatgg tgttcgatgg aaaaaagata aaacactagt gttcaataga
    49981 tatctttcat taatgggacg tggtaatggt aaaactggtt ttgcttcttg gaacaacttc
    50041 tttctactaa ccgctaaaca cggtattaaa aattatgata ttgatatcta tgccaataat
    50101 gaaagccaag caaagactag ttttgatgat gtatttaaag taattaaaga tcatcctgat
    50161 ttagataaaa aagtatttaa agctacgaag gaagttattc aaaatatcgc tacaaacagc
    50221 aaacttcgtt ataacacggc aaatgctaga acaaaagatg ggaagcgacc aggtgcaaac
    50281 cgctttgatg aaattcacga aaatgaagat tattcaatga taaatgtggc tacttctggt
    50341 ggtggtaaaa ttcgagatta tagagaattt tatgatacaa ctaatggtca tgttcgtggt
    50401 ggtccgcttg atgacattat agaagaatca aaaatgattc tttctggaga acttggaatt
    50461 gacaaggatg gagcagaatt ttctagtttg tttccattta tttgtcgctt ggataacgat
    50521 aatgaagttg atgatcccga catgtgggaa aaagcttgtc caactattaa ttacaatgca
    50581 gatttaaaac ggaaaatgtt tcaagaatac tctcaaatgc aacgtaatgc tggtttaaga
    50641 cttacgttca tgaccaaacg aatgaacaga cctatggaag atacacgatt tgctgttgct
    50701 tcatatgatg atgttctgca tacgaaagaa aaagaatttc ctgaaaaaat ggatgaagtg
    50761 ataggaacag tcgattttgc tgatagacga gattttgcca gcgttgggtt gctaggaaaa
    50821 tacgataaag atgtttattt tacacaacat acttttatcc acgaatcagc ccttcgatta
    50881 caaaacatca aacgagaggt tatagatatt tctatagatc aaggaaaatc acagatcgtt
    50941 catggaaaaa atatagaagc tgattatatt gtaggttggt ttcttgaaat gagtaataaa
    51001 tattatatta aaaaaatcgc tatggatatg taccgtgcaa aaatattgaa gcccgcttta
    51061 gaagaagcag gttttactgt ggaaattgtt cgaagcggat ctgttacaca tggtatgtta
    51121 aaagatctgg ttgatgacct ttttattaat caacgtttat tttttggtga cgatgcgatt
    51181 atgcgttggt attgcatgaa tgtatatgaa gagcatattt ctaatggaaa tatacgctat
    51241 gaaaaaatag aacctgaaac tagaaaaacg gatggctttt tttcattcct tcatggtttg
    51301 aattttttag atgatattta tgattctgct cctgtaacag tcacaaatag ctcagtagaa
    51361 aatacaggaa ctggatttac tcctctagta ttctaacttg aaaggaggtg agaaagtggg
    51421 gatttttcaa aaggcggtag gatacttcac aaaaaaagca acggttcctt tagaagaata
    51481 cttttgtaaa ttgcaagttg attttgtgta tcgaaaattt gcgattgaaa cttgtattga
    51541 tttgattgca aatgcgatga gtaaagcgga attcaagtca tatgaagatg gaaaaaataa
    51601 aaagaatgat ctttactata ggctgaatgt agctcctaat aagaaaaata atgcaacaga
    51661 atttagaaaa aaactgatca ggagattaat attctacaat gaagtattga tcgtttctcc
    51721 gtctaataat tctagcgaaa tatttattgc ggatagttgg gatgtcacag aatatgcatt
    51781 gaaagatgat gtgttttctc aagtgcaaat taacaacata gtccttgata gagaatttct
    51841 agaaagtgat gttatctata taaaatacgc agatcaacaa attaggcaac tagtcgatgc
    51901 gtattatcaa gcgtatggga aactcatttc tagtgccatg aatgtttaca agcgctctaa
    51961 cgctcgtaga tacgtactga aagggaattt attccgaccg caagacaata caacacaaga
    52021 tcaaatcaat aaaatgatga catcacaatt taaggctttt atggaagctg ataatgcagg
    52081 tgcggtattt caattacaaa atgagtacac attagaagat ttcagcggaa acttccaaag
    52141 caattcaaga gatataaaaa acttaataga cgacatcttt gagatgacag cagcagcgtt
    52201 tcacgttccg aaaaacctac taaagggaga catgagtggg ttatcggatc aagtggacgc
    52261 ttttttaatg ttcgaaatca taccgattgc tgaacttatt caggatgcgt ttaacgctag
    52321 tctctatgaa gtagaagaat acttgtcagg gaattttgta cgtgtggata caactatgat
    52381 caagattact agcttcaaag atttggttga cgctattgat gtaggcatta gaaatggagt
    52441 atttacaatc aacgaaggaa gagaacgcgt tggaaatgat cgctctgata aggcgatggc
    52501 agatgaaata tttataacta aaaacaatca acaagtatcg aaaggaggtg aggcgaatga
    52561 cgacaatgaa aacatttcta gcagtaaaga atgaaggcgc agtaccgcaa atttttattc
    52621 agggatttat tggttctagt tggttctttg aagggaatac tgacaaggga atcaaaaata
    52681 ttttggatag tctaggtgat caagaagaaa ttgaagtagt aattaattca aacggtggag
    52741 acgtatttca agggattgct attgggaact tacttaagtc aaataaagca aaagttaacg
    52801 ttgtgattaa cggcttagcc gctagtgctg cttcaattat cgcaatggct ggcgatacta
    52861 taaaaatcta caacaatgca caattgatga ttcaccgcgc ttccacatac ggagaaggaa
    52921 atgtcgatga cttccgtacg attgctgacc aactggaatc aattgataaa tcggtaaagg
    52981 cttcatataa aacacgattc aatggcacag atgaagcatt gcaagaactt cttgaaaaag
    53041 aatcgtttat ggatgcagaa acagctttga gttatggatt ggtcgatgaa attatcgatg
    53101 cagaaaatag ctcaggtact gaagctaaaa aagaacaaag cgttgaagaa attttgaatg
    53161 acgttaaaga aaaaagagca gaaaaaattg ctgcatttac agcagcatta aataaaacat
    53221 ttggacaagg agatgtaaaa taatgacagt taaaaattta aaaggtgtaa cagctgcaag
    53281 cgaccaattg atgaaagctt ttaaagatgg taacgaagaa tcttttagcg cagctatggt
    53341 aagcttatct aaggaaattc aggataaaat tttagaagaa gcaacagcaa aaaatcaaga
    53401 tcaattagta ttaatgaacc gtggtcagcg tgtattaact acacaagaaa caaaattcta
    53461 taacgaagta gtgaaaaacg aaggttttgc aggggtcgaa gaattagtgc cagctactgt
    53521 atttgaacgt gtatttgaag atttagaaca atctcatcca ctattgcaaa aaattacttt
    53581 tgttaacaca actggtgtaa cagaatggat tgtgtcacgt ggagtcaatc cagcatggtg
    53641 gggtaaactt tgcgaagctg ttaaaaaagt tttagataat ggctttgatg taattaacat
    53701 gaagcagttc aagctatcag gttatattcc tgtatgtaag gcaatgcttg atttaggtcc
    53761 agtatggtta gatcgttatg tccgtactgt tttagtagaa tcattgagaa ttgcattaga
    53821 acaagcaatt gttgatggta ctggtaaaga tatgccagtc ggaatgatgc gtgacatgag
    53881 caaacaaact agcggagaat atgctgaaaa aaaagcagaa cctattacag ctttagatgc
    53941 tgtaactatg ggcggtttga tggcgcgact atcaaaattc aatatcgaag gtgtgaatga
    54001 tccgatttat cgtaatgtga atccttctga tgtggtccta attgtgaatc caactgatta
    54061 ctggtctaaa gtattcccag ctaagactgt actaactgct aatggagaat acgtacaagt
    54121 attgccagta ccagtttcag atttgcagtc aacggctgtg ccagaaggaa aagcagttat
    54181 tggggtagcc tcagattact tcatgggtgt aggatctaca ctaaaaattg aagcttcaga
    54241 tgaataccat tttgttgaag acgaacgcat ttatctagct aaacaatatg caaacggtca
    54301 acctaaacgt aacgatagtt tcattgtatt agatattagc gctttgggaa ctactactac
    54361 aactacaaaa ccaacaacca caacaactac aacacaagcg taggtgatca gaatgaagta
    54421 tattctttgt cagccggcaa tcaatcggtt taaatgggag cttgaagttt gtttaactaa
    54481 tctgaagaaa ctaggaatca aagatatcgt attgcttttc agcagacacg atgatcagat
    54541 tcctattttt tttgagaagg aatatggtgt tgaagttcat gtgtacgatg atctgcggga
    54601 cgacaaagag tatattcctt cgattaaacc atatttatgg tggaaatatt tagaagaaga
    54661 tcattcgcgt gaggacgacc gatatttcta tatcgattcg gatgtcattt tcaataaaag
    54721 aattaatttg cgcaaattgc cttctaaaga tgatgtttgg tattgtagcg actgctgtag
    54781 ttatctaagt cttgattata ttagaagctg tgaaaacgga gaaaatattc taaaagatat
    54841 ggcaaacatt gtaaatgtta cagtagaatc tttggaaact ataaacacta attcaggagg
    54901 cgcacagtgg gttattaacc gtcctaaagc gaattattgg aaaaaggttt atctggattc
    54961 taatcggcta tatcgctacc ttagagggca aaaaacaaat atacaaatct ggacagccga
    55021 gatgtgggca cagctttgga acatgatgta tttcaatatt ggtcctaaag ttcacgagga
    55081 attagacttt tgttttgcta ctgatccaat agaaaaagtt aaagaagtaa aaatcttaca
    55141 caatgctgga gtaacaacaa acgatgaaga tttatttttc aaagggagat acgtgacttc
    55201 tacgcctttt gatgaagatt tatcatttgt aaacaagaaa aaatgctctt acgcatatgt
    55261 taaagcaatt aaggcggtgg ttagatgacg cctgaacaag tgactgaaga attgctaata
    55321 gctgtgaagg ataatattta cgttacctgg aacgaagaag atgagtcaat taaaaagatg
    55381 atagctaaaa atgctgttta tcttcaaagt aaagtgagta caacactttc tttttctcct
    55441 gaaagcttag aatacggatt gctaatcgaa agatgtagat acgactggaa tcgtgcttta
    55501 gatgagtttg aacaaaattt cgctagtgag ttattaggtt tcattcaaca ttatgcgcta
    55561 caagaatata ttgcaggtga tgtgaatggc gaataatcgt agactcgaag aaacattcaa
    55621 cgatggttgg ttaaagattt tgacgcaaac taccaaaaga aatgaactag gaaaaaagat
    55681 tggtgtagaa gatacagaaa tcacttcttt aaaatttaga aatctttcca tgagagatag
    55741 tgatataaca gctatggatg cgatgggatc gaaattaact aagaaagtaa agactccatt
    55801 tcatccaatc gccaagaaat ttaataaaga tcaatatttt atcgtaatcg atagtatgcg
    55861 ttacaacgtt atctatgccg attacgataa tttttatatc tatttttatc ttgaaagtgt
    55921 gggtgaatat ggtgattgat aattctaaag aaaaagaacg tttaaataag caaatttctg
    55981 ctatcaaaac ttccttagaa gagcattttg gcctcaaact ctttcaagac tccgtaggcg
    56041 aggatgagct acctgatgat tttaattact tcattctcga aacaggagaa atagaaatga
    56101 tcactgagcc aaaatatagc gtgggtcaaa atctatatct aactttctat tcagaaaata
    56161 gagaagattt aacaggagac tcactagata ttatttcatt gattcaaaat cgttcgattc
    56221 gttttcagag aatggatccc aatcatttaa aactagagaa ccaagatcgc tatatcgatc
    56281 aattggtatt tacgtttaga cgattattga agagtgattg tcatggctaa aaatagttgg
    56341 gagctaaaaa taaatggaca tgatgaactt cttgtgcgga tggaacgcta ttcaagcgag
    56401 agcgaacgac tgattaacga agcattgaaa tcaaaaggtt cggctattgc agtggatagg
    56461 attacagaaa aaattcctgt ttctgaagca gatttaagaa gagggcacca acacgcaaaa
    56521 aatagtcgtc cacttaagac tcaatacatt aatttgggtt tcatcattag acctacaaga
    56581 aaatttgagt atttaaaata tcctgatttg gggataggta cttctaaaag aaatcagccg
    56641 gacgaattta tgagaagagg attaggtctt gcacttgatc caattacaga acttctgatt
    56701 cgtcaattcg ataaattaaa taaatagggg gaacaacaat ggctaaaaca aaaactgtag
    56761 taacaacgtt cgataacgta agtatcaaac gaattgcttt taattttaag aacgcaggaa
    56821 atgcaatcgc aacgaattgt aacggacaat tagatggcga aacagaaatg caaacggtgg
    56881 ttaaaaaatg tggagcgaca gaagtaaaat caaaatctaa accaatcaat atgacggtaa
    56941 caattactgc acatgtaccg atggaagttt atcgacgttt caatgggttg aaacaagatg
    57001 gacgtattaa accaggcatt tactcttacg gtcctgattc cgtaggcgaa gatttctcac
    57061 ttgctgcaga gatcgtggat gacttcgaag aaaatagaaa gttagttggt atgttagcat
    57121 gcacttcgaa tacaggatta acattctcta ttgaaaatgg tgcggatgaa gtagctgcgt
    57181 tagaactaga aacaaaagtt atgcaagatg aatttggtaa attttatcat gaagcaattg
    57241 ttgcagaact tgaagaagac ttaacagatc aatggatgac gaatctatct gctgatgtga
    57301 ttaaaaaaac ttcagttgtg acaactacgg ccactcaatc acagtaaaaa aaacggaggt
    57361 agcgaaatga acgaagatta ctcaaaaatt gaactaaacg atggaacaat tttgaattta
    57421 gaacctaaac tgaatatcaa gaaattattg atgatcaata gagattttaa cacagacgag
    57481 tttgcaaaaa tgactgtggg aaaaggatcc atggatattt ctgttattca aggtgcaaag
    57541 gctgtgtata ttgcttaccg ccaagcgaac atgactgatt atatttcatt cgatgaattt
    57601 atcgataaat gggattttga tatggctact gccagctata tttatcaatt gatgatgttc
    57661 aaacaagcac gcgatgctta tcaaaaagaa tttgaaaaag caaataagga aaaaaagctt
    57721 caaaagtaaa aattccaaag ctcttagttg aaacgtgggt cgatgtctat tcgatgttga
    57781 ccgacgtttt ttctatgcct tcagatttgg ttttaagcga tatctgttta gatgacattt
    57841 tgcaaatggc ttacaacaag agtgcttatg aaggatggaa aaactatgca ataaaccaat
    57901 cccagaaaaa ctaaagaaag gaggtaaaaa atggctaaaa agagaacaga agcagaagta
    57961 actttcatag ctaacgatga cggattgaaa tctacgttaa aagaaatcag tgctgaatta
    58021 actaaaaata gagcagaatt aaaactagaa caagctcaat tacaacagac tggttctgaa
    58081 tcagacaagt taggaagtaa attatcttct ttagaaaagc agtatgaatt acaaagtcaa
    58141 aaagttgaag taactagcca acgtttagcc aatgcgaaaa aatattatgg agaaaattcc
    58201 accgaagtta agaaacttga aagagaactg attaatcaac aaacagcgca acaacgtttg
    58261 tcaaacgaaa ttgataaaac gagtaatgca ctagctcaag caaaaggcga aatacagacg
    58321 tacgagtcta caatgcaaca gttggatagc gaacaaaaaa atgttcaagc tagtgcttct
    58381 ctgattgaat ccgaatacaa aaaatggcaa gcaactgctg gtcaatcagc ttctgaagcc
    58441 gagaaattag cgaaagccca agaatatgtt tctcaacaat ctgaaaatgc ggagaaaacg
    58501 atagatatcc taagacgaca gttagaagct acacagtctg aatttggcgc tacatccaca
    58561 gaagcaatgc agatggaagc gaagcttaat gatgctgaac gtgaatttga agagttagga
    58621 caagctgcta aaaatgtaga tacaactaac ttggacgata tcggaagcaa aatagatatg
    58681 aataatttaa tggaagcttc tgacgtttta agcgacattg gcgataagct tacagaatta
    58741 gggaaacaag cagtggactc tgctaacagt gtaggtagtt cccagagtaa gatacaagct
    58801 aattttggtt tgtctaaaca agaggctgaa gaattaacga atgtagccag agacatttat
    58861 tataaaggtt ttggagaatc gttagatcag tccacagatg cattgatttt ggtaaagcgt
    58921 aatttaggag atttaaataa tcaagattta caaaatatca cggaacaagc tatggtccta
    58981 gaaaacacca tgggcgctga tatggatgaa acgttacgtg gtgtaaatgg cttaatggtc
    59041 aatttcggct tgagtgctca agatgcaatg gatttaatgg tttcgggtac tcaaaacggt
    59101 ttagataaaa cgcacgaatt aggcgacaat atggcagaat atagccaatt atggagtcaa
    59161 atgggatatt cagctgatga aacgttcgga atgcttcaaa atggtttaga tgcgggtgct
    59221 tataaccttg ataaagtcaa tgacttagtt aaggaaatgg gaatatcgtt aacagatggt
    59281 cgatttgagc aaaacatgga tatgtttagt gaaagtacta gaaaagcttt tgaagagtgg
    59341 aaaaatggcg gaggaacaca aaaagacgtt attaattcca tgattcaaga ttttagcaat
    59401 atggatggtc aatacgacca attaaataaa gcttcgacaa tttggtctgc gcttggcgaa
    59461 gataatgcga tgaaagttgt ccaatcttta actgatgtta accatacatt tgatgatgtt
    59521 agtggatctg cacaaaaaat gaatgaagat tctactactc cgttgcaaga gttgaacggg
    59581 aaaatagctg aattaaagga ttcattagct cctataggca acacaatcat agatgcactc
    59641 gaaccagtaa ttgattttct aggaaagatg gctgatgcgt ttaataatct tccacaacca
    59701 gtacaggatt tcattgttgc tataggtggt cttacagcag catttggcat actgttaccg
    59761 gcaatactag ccgtgtcata tttatttggt ccgatgatgc ttataattgg aggaattata
    59821 gctgttatag caggcgttat tgtggcaatt aagaactggg gtgcaattac tgactggttt
    59881 agtggtttat ggaaaaaatt tactgattgg ttgggtgata cttgggaaag tataaaagac
    59941 ggagcctcat cagtttggga tggggttaaa gaaacctggt ctggatttgt agattgggtt
    60001 caagatattt ggcaaggagt ttctgattgg tttggagagc tatggagcgg attagttgaa
    60061 ggagcttcca acatctggca aggagtccaa gaaacttggc aaacattcgt tgattgggtt
    60121 tcaaatattt ggaacggagt caaagaagta tggtcgatta tttgggcaga cattgtagga
    60181 attgttcaaa taccatggac attaataacg tcattgattc aagctggtat taatattatc
    60241 gtgggtattt ttgatgtagc tggacagtta ttgggcgcag cttggcaagc tgtttggaca
    60301 cctatttctg atttccttaa aaatacttgg gatactatga cacaatggat aagtatcgct
    60361 tggaatggga ttgtaactac attccatact atatttgatc cagtagtggc atggtggaat
    60421 ggtatatgga cagctattag tactacggct tcaaatattt ggaattcaat tagtgcaaca
    60481 gcttctagta tttggaacag tatcaagaat acaatcacta gcttggtaca agcagctgct
    60541 acagtaattc aaaatatttg gtcaactgta tctagttggt taggtggaat ttggaattca
    60601 atcagctcta cagcatcaaa tatctggaat agtgtgacta gtagtataag caatgctata
    60661 aacgcagcta aaagtgccat tcaaagtgtt tggaatagta tatcttcgtg gattagcgga
    60721 atttggaacg gtatcaaaaa tactgctttg aatctttgga atggaattac aagcactatt
    60781 agctctaaag taaacgatgg aaaaaatgca atttcaagcg gttggtccaa tctaacaggt
    60841 attgtttccg acatattcaa taatgttaaa agtacaattg ctaacatatg ggaaggcatc
    60901 aaaaagactg ttagcgctcc aattgattgg attagagaca aaatcagtgg catttttgat
    60961 aatttgaata tttctatacc acatattccg ttaccggaat ttatcatgga aggcagcttt
    61021 aacccgctaa aaggtcaaat cccccatttg cgtgtaaaat ggcatgctaa aggaggtatc
    61081 tttactaaac caactttact aggtggaatg aacggtgtcg gtgaagcagg acctgaagca
    61141 gttttacctt tgaaaagatc tgttttgcaa gaaattggtg atcgtatctt gagtagcaca
    61201 tcagtttcat ctagggcaca aacgattcaa cctgtgaata actacgaatt caatttcaca
    61261 attgatggta acgcagatga ggttactatg aagcaaacaa ctcaacaaat cattgatagc
    61321 attacaaaaa ttcaaaatga taatgcttcg gcatggcgtt aaacaggaga gtatttctcc
    61381 tgttttttta gtattaaaaa ggatgtgaaa aaatgactga ttgtatacat tctataatcg
    61441 atggatttcc tgattatttg cataaattgg ctttagctga aagaccaacc ataccttctc
    61501 caaaaagaca gagagttgaa acttctgttt taggtaggtt aggtggctta gtacaagatt
    61561 actcgtttga agatatgtcg tttacattgc actataacta tttagaggat gtggaagacc
    61621 atcaagcgtt caagcaatcg ttttatatca tgcgtcattg gttaaactat gcaaagaaat
    61681 tagaattctc tgacgatccc aacgtctatt acgttatcca gactatcgat attggggatg
    61741 cagaaaacga tattgttgaa tggggagagt tcgatgtaaa tattactgcg aaaccattcg
    61801 caagagttca agaagatgta cctataaccg tagataaacc acagtcattt aacttgctga
    61861 ataatagttt agaagaaagt tttccaaaga ttatcatcac tccttcagct acttcatgcc
    61921 agttcatctt aaatgattat gtgtttagtt tcgaaggctt agtagcagga actgatgtag
    61981 tcattgatag tgatttgatg ctttgctacg aagagcaatc ggacggagat attttagatc
    62041 ggtccaacaa aatgaagacc atgcaatatc cgacattgca agtggatatc aatcatttta
    62101 attgcactgg tttgagcaaa atacaaattt atcgtaacgg gttaaggtag gtgaaataga
    62161 tgatcgataa tttaataact atttacgata aaaatgacgc gaataattta gctgaacatt
    62221 tatatgatac gcaaggttta ggcgctttgt cagactggtt aacagctact gttagcaata
    62281 aactaaacgg agccgagata tttcagggta cttattcaat aaacggaact aatgcagatt
    62341 tgattgtaga aggacgtatt attcagtgtt atgtagatga aaatcgagca aaacagcgtc
    62401 tacggattta ttatgcaaaa acttctgtaa taggcaatac gatagaagta aaagctgaac
    62461 ctattttcaa tgatataaga aaatcggtgt tgaataaata tgacagcgga acagaaaaga
    62521 tcactgctac tcaggcatgg caaaacgcaa aagttttagc gaaaccagct atcccttcgc
    62581 agttttcttt ctcgtcatta gtagatacgc ttgctaatgt gaagatagaa aaggcgaatt
    62641 ttttagaatt ctttggtgga aaagagggat ctattctaga tcgatttcat ggtgagtttc
    62701 taaaagataa taacacatta cgtcatgaaa aaagtctagg tacggatcat aaaatcaaag
    62761 cgatttatac taaaaactta actggtcttg acttagagat tgatgctcaa agtgttttag
    62821 ttggagttta tccattcatt agcagctctt cagaaggaga agacgagatc actctaccag
    62881 aagaagttat tttcacggat tacgtggatg attatcctgc tggatatgtt tcttttgttg
    62941 attttaaaga caaagcgact gatgtagcca cattaaggga agctgctaaa gactggttga
    63001 aaacaaacat agataaacaa aaaccacaag tgagtggttc gattgaatta gtaccattga
    63061 ggcatcaaag aggctatgaa aaatttgttg atctagaaaa agtttcgatg ggtgacggag
    63121 tagatgtgta tcatccacag ttaaaagtga atatgtcagc gagaattgtg gaatatacgt
    63181 ttaatgttct aaccaattca tacgataaat tagttgtagg aaacgtcaaa acaaacttct
    63241 tagaaaacac agagaataat gtcagcaatt tgattaatga tgccattgat caattgaaaa
    63301 acggtggcga aatcagtgat ttactcaatg atattgtaga tcatcaaact gatatgatta
    63361 ctggtcaaaa tggtggttat gttttattag atcctaaaga agcgcctagt cgtattttga
    63421 ttatggacac accagataag aataccgcaa ggaatgtttt acaaatcaac aatgctggta
    63481 ttggtttttc taaaactggc attaatggaa catatgaaac ggcatggacg ttagatggcg
    63541 gattcaatgc ctcgtttatt acggctggtg aaatagtagg aattactatt agaggtacta
    63601 cattaattag tgatggtgct gattatagaa caagtattgc taatggcaaa atgacttggt
    63661 actcaaaaaa agttaacaaa gatattatgg agctagaagc acgtgattat gtaagtgctg
    63721 atgccggtat tgtatcatac accatgaaaa ctggtggtgg tttcatgatt agaaatccac
    63781 agggtaactt ggtttttagt acgtgggata atggtaataa cagaccgttt ctatcttttg
    63841 gtgcgcccaa tttcaggtat agcaatgcta gttatgtaac ttctggcgac ggtagttctt
    63901 taagcattaa tggtagtgcg ggtaactcat gggaatttaa ggtagctggt aggactatga
    63961 aatttactag tgatggtatg ctaacgttac caggttgttt ttttggttca tgggaagatg
    64021 ggaaacttgc taggtttgaa caatcaacgg tacaagtata taaagatttt actgttagag
    64081 gtactaaaaa ctcaactgta ccaacagaac attatggaca acgactattg aacgcttatg
    64141 aaactccaga atattatttc gctgattatg gggaagccgt tacaggtgac aatggtaaag
    64201 ttcgtgttga tattgacccc atgtttgctg aaacagtaaa tctaagtcgg tatatgacac
    64261 atgtgacacc tacagaacta gttttgtgtg ctgttactca tgaagatatt gaccatttca
    64321 tcattgaaac tagtaagcca aacgtattag ttagatggaa tttagtggca caccgtctag
    64381 ggtatgaaga tattagatta aaagaggata cagcatatga tagcacagtg cttgaccaaa
    64441 aacgttttta aaacgaagac aaggaggtat ataaatggct agcagtttat ataatttggc
    64501 tttagatttc agcaaagaat taaactacac caaagctatt atggctcgtc aaggtgataa
    64561 agggattacg gtgacggtta aaccgtttct aaatggcttg cagatggata cgagtggcgg
    64621 aacatttact ttaaaaggaa caacaccatc taaccgttac gtagataatg ttgcaactag
    64681 tgtaactagt gaagaagtca cgttttctct tgatggcaca tttatgagtg aagcaggata
    64741 ttataaacac tgctacgtag aatatagaaa agacaatcaa attttaacaa cgcaagatat
    64801 catttttttc tcactaggag tgtctgacat ttcgcaaggc caagccgatg aatatgtttc
    64861 gcaattagaa gagttgattc gaaagtacaa cgaaactttt gatgctttta tggctgaaat
    64921 caaaggtaga gtggatagct taaatcaaca gattactgat ttaactggtc aagctaaaac
    64981 gctacaagac aagttagatg ctctgaaaga agaaatttct aagttaggta acttacaagt
    65041 gatgtacagt aacagcatcg acttcgggga ctatgattat tcggagaacc cgaatttaat
    65101 gccatatatt acagaacctt gggttggacc tttgttaggt aatggacata cagttaaaga
    65161 tagtgttaaa agggttataa ctcatactaa aactagaaca gctaattccg gcgacatatt
    65221 atcgcttggc ttaggtattc cgtgtacagc ggaagctaat aataggtatc ttataaccac
    65281 tttacgacca tctacgacat acacattaag cgttactatg agtgtcggtt cagattggac
    65341 tggagagacc aatactatag gggttaggct tagatattta aatgaacaag gtggtataga
    65401 actgcccatt aatgcattaa taccagcaaa tgtagaacgc gataaaatgg tcactcatac
    65461 atttactggt ataacaaaag ataatgtaac tagcataaca aactgttatg ttgaaatatt
    65521 ctcacttaat agtgaatata aaggaacggt tagtgtcagc tatgacgtta agttaaaagc
    65581 acactaccct aacttactag atggccctta ctggttaggt aaagttcctt taggcgagaa
    65641 tattgctgac cctacagttg tctttccaca caaaactagt gaatatatgg tttatggtag
    65701 acgcaataca gaaaactata tcgctgacca aacatatacc atatcaatga aagcaactaa
    65761 actaacagtt caatcgtttg ccgtgtatat tgctgctggc cgcgttaaag taggagacat
    65821 gaagcctact gaggggttag ctaatacatg ggagttaact tttactgtaa ctaagcaaca
    65881 tatagatagt ggggtaacta attatctgga aatataccaa tacccgtcag ctacaaaagg
    65941 agctgttcaa attgagtggc tcaaactaga aaaaggcaat actcgaaccc cgaatattag
    66001 tgagtataaa tatcgtggta ctggtatgcg tgattcaaac aatccaaaag attatgtttg
    66061 ggatctagca ccagaatatg tcgaagataa tttggccaca gatattaaaa tttctgaaat
    66121 tactggtaaa gcaaacaatt ataccgatgg gaaagtatcg gagattaatt cgcagttgac
    66181 tgcttcaatt aatgaagtag acaccacagc taaggatgct caaacaaaag cgaatgctaa
    66241 tgcgactgct atagatgaat tagacaataa gatcgatgaa cgcattaatg atacagctac
    66301 taccacatta acagttacaa acgggaatac cggatcagca aagctttatc gtgaaggaaa
    66361 aacagtttct atatattttg tggctttaaa cggaaaaagc agtggtggaa atgattcaac
    66421 gatactaaca attccagaag gctatcggcc accaattagt tttgagcaac tggttggctc
    66481 gatagaccgt tctactttga acagtgctca gttatctatt ggtgcagatg gagccattaa
    66541 atggcgaaga aactcaagtt atggatcgga ttataccttt gcaattactt acacgattta
    66601 gaaaagcgtg aatcgatatg aaggcagcat atagaccaat tgaaccttac ggattcgagc
    66661 aaatcattgt gaatgatgaa gaacatttac cggaagaatg cacagaagtc gaaccaccga
    66721 ttccaaattg gaaaccgaaa ttcaattact gggagggaaa taaatgaaaa acatttggaa
    66781 atatggacgt actggcggag agtacgcagg aaaagtattg gacgacatgc ttgtatccgt
    66841 tccttacaca gatcagccac cgcttgaagg aattcgtgct gatggcgaac cgttaacaat
    66901 cgctgatcaa atgtttgatc ctaaattgaa tcaatggatt attttagcga acgcactaga
    66961 tcacaacgat ttaaacaatc tcaaagcaat gtatgagtcg ttagaaaatg agaacggcga
    67021 tttaaaacag atcaatgcca aactcatgct aagcgatgta gcaattaaac aggaaaatac
    67081 tgcattgaaa gaaaaagcgg atagtttagc acaaatcaat tcaaaaatga tgcttgcttc
    67141 gttacaaaat agcaaagaca tttcagaaat taaagagcaa ctaaatccag cttcaaaggg
    67201 aggtgagtag tatgtttagt tttagcgatg tgaaaatgat gtatgattgg ggctgtttca
    67261 ctaacgaaca agtaatggtt ttcgttccgt tgtgcattac tgaagaaaaa gcagataaaa
    67321 tcattagcaa agaagagagc gcatcttaat tgatgtgctt tttattttga ttcaaggagt
    67381 tgtcacatga ttaatttagg ggaatgggga gcgatagcag gatcaataac cgctatcgtt
    67441 tctttgattt tattagtaat aaaaccaatt actgcatctt tctcgaagat tactgagact
    67501 ctttcaaaag taagtcacaa tttagatttg ctgactaaag atttagaatc gagcaaatca
    67561 gatcgattga tgattcatga agaactaaag aaacacgatg aaagattaga tacacatgca
    67621 gaaaaattgg tagaacacac gcaacaaatt aaaactttat ttagggagag aagaaaatga
    67681 ataataaaac gttcgaagta ctaaaatggt tcgcactggt aattattccc gcactagcta
    67741 ctttcgtggg gttagttggt aaagcgctca attggcagta cacagatatc tgtgttgtca
    67801 tcattactgg ttttggcgcg tttttaggga gtgtgttggg tgtatcaaat cgaacctaca
    67861 aaatgttctc ggctgaaagc gaagaaggag gaaacaaatg aaaaagaaaa ttactattac
    67921 tgcgatgagc ctgttaacgg ctcttttttt attacccatt aatacgtttg cttatactat
    67981 taatgacgag tataatttag cgccgaatca aggagactcc agattagcaa ttcctaacaa
    68041 aattattttg cacgaaactg gaatagatgc accagcaaga aacgtagccg ccaacatgaa
    68101 aaataattat aacggaagca atccttatac tacagatgtt attggtgacg gtgggattgt
    68161 ttaccgtgtg ggtgagcaag gatatgtttc gtggggagct ggtaacgcta atccttatgc
    68221 gcctgtacag attgaattac agcgcacata tgataaagca ttgtttgaaa aaaactatcg
    68281 agcttatatt gaatatacaa gagatagtgc aaaaaaatat ggaattccat tgactcttga
    68341 tcaaggaact tctttattta caaaaggaat catttctcat ttgtgggtga caaattatgt
    68401 ttgggggaac cacacagatc catatggtta cttatcgcaa atgggagtta gcaaagaaaa
    68461 gcttgcttat gatttagctc atggatttac cgatgaaaat ccaacaactt ctgaaaacaa
    68521 gcctgtcatt gatccaacac gagctggtgc agctaatcct acgctgacag atggaacaaa
    68581 tcacgcccac attgatcagt ttggggaaat cgaaaacgca aacttgcatg tggctggatg
    68641 gcacattgct aactataaat acgagtatat tttcattatg gactacaata ctgggaaaga
    68701 attagctcga gtaagagctg atggaattta tagaccagat gtaaaccaag cttataatac
    68761 ttctggaaat gttggttatc atgtatcttt caatatgcgt aattttccta gtaagaaagt
    68821 ctatgtaatg atgcgggcaa cgaatgatcc agagggaaac actaaaggcg gtgcgcaaga
    68881 tttccatgac aaacgttggt atttaaatat tcctaaacga taaaaatagc tcctcgttga
    68941 ggagcagtac ataactatat tgacaactat aaaaattatt cgataaaata gtgatgttat
    69001 cgcatatctt cactatcacc cataaatagt cacactccaa gctatgcgat aacaggtttg
    69061 ttgccacaca ttctactggt tgattgttta tggctttatg tggcaacaac cagtaccctt
    69121 agctcagttg gtcagagcag acggctcata accgtccggt cgtaggttcg agtcctacag
    69181 ggtacattaa cgtagccatt tgaatcgttc tgtgttagaa tttttttgaa gagtattata
    69241 caagctaaag cttttcttca ttgccactca aatgagtggc ttttttatgt atccttttat
    69301 ggattaatga aaggatgttt cacatagtta tacttctgta tatttgaaaa gttttacttt
    69361 gatttttaaa tagaaagaca tttgggttaa attgtgagat aataataaag aagagtttaa
    69421 agcgcacccc aaaccacttc cccataagtg tgttacgctt taaactcttt tatatttgaa
    69481 gccattaaaa agcataccat atttttgaaa aaaagtgaga aaaaaggctt acaattggag
    69541 tggtagttaa ttagtgactt atttttgatt ttatagcact gatactataa aatatagata
    69601 tcatcatatt acacaatctt aatactaact taaaaaatat ctcctttcac aagtatggtg
    69661 ataaaattcg ttccgggcta cctttttagg tagcctactt taatctttat acctttctgg
    69721 atcaacgaaa gtatacttta tatagtcata acgccgatga tcgctacgtg cgtccggcac
    69781 gtcagtc
//
LOCUS       DAXLPY010000005        67411 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.005, whole genome shotgun sequence.
ACCESSION   DAXLPY010000005 DAXLPY010000000
VERSION     DAXLPY010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.005"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            53..1501
                     /gene="cls"
                     /locus_tag="ACF3UF_000388"
     CDS             53..1501
                     /gene="cls"
                     /locus_tag="ACF3UF_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFD3670544.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            1838..2695
                     /locus_tag="ACF3UF_000389"
     CDS             1838..2695
                     /locus_tag="ACF3UF_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFD3670545.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            2810..3730
                     /gene="pstC"
                     /locus_tag="ACF3UF_000390"
     CDS             2810..3730
                     /gene="pstC"
                     /locus_tag="ACF3UF_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFD3670546.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            3730..4614
                     /gene="pstA"
                     /locus_tag="ACF3UF_000391"
     CDS             3730..4614
                     /gene="pstA"
                     /locus_tag="ACF3UF_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFD3670547.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            4629..5435
                     /gene="pstB"
                     /locus_tag="ACF3UF_000392"
     CDS             4629..5435
                     /gene="pstB"
                     /locus_tag="ACF3UF_000392"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFD3670548.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            5451..6209
                     /gene="pstB"
                     /locus_tag="ACF3UF_000393"
     CDS             5451..6209
                     /gene="pstB"
                     /locus_tag="ACF3UF_000393"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFD3670549.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            6222..6899
                     /gene="phoU"
                     /locus_tag="ACF3UF_000394"
     CDS             6222..6899
                     /gene="phoU"
                     /locus_tag="ACF3UF_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFD3670550.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            7476..8168
                     /locus_tag="ACF3UF_000395"
     CDS             7476..8168
                     /locus_tag="ACF3UF_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFD3670551.1"
                     /translation="MLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISIL
                     FVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVI
                     GSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPIS
                     VLFFLTVRRLKR"
     gene            8165..8932
                     /locus_tag="ACF3UF_000396"
     CDS             8165..8932
                     /locus_tag="ACF3UF_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFD3670552.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            9032..10600
                     /gene="liaX"
                     /locus_tag="ACF3UF_000397"
     CDS             9032..10600
                     /gene="liaX"
                     /locus_tag="ACF3UF_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFD3670553.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            10897..11217
                     /locus_tag="ACF3UF_000398"
     CDS             10897..11217
                     /locus_tag="ACF3UF_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFD3670554.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            11217..11567
                     /locus_tag="ACF3UF_000399"
     CDS             11217..11567
                     /locus_tag="ACF3UF_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFD3670555.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            11734..12672
                     /gene="hprK"
                     /locus_tag="ACF3UF_000400"
     CDS             11734..12672
                     /gene="hprK"
                     /locus_tag="ACF3UF_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFD3670556.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            12687..13517
                     /gene="lgt"
                     /locus_tag="ACF3UF_000401"
     CDS             12687..13517
                     /gene="lgt"
                     /locus_tag="ACF3UF_000401"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFD3670557.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            13561..14586
                     /locus_tag="ACF3UF_000402"
     CDS             13561..14586
                     /locus_tag="ACF3UF_000402"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFD3670558.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            14601..15539
                     /gene="galU"
                     /locus_tag="ACF3UF_000403"
     CDS             14601..15539
                     /gene="galU"
                     /locus_tag="ACF3UF_000403"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFD3670559.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            15664..16104
                     /locus_tag="ACF3UF_000404"
     CDS             15664..16104
                     /locus_tag="ACF3UF_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFD3670560.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            16107..16709
                     /locus_tag="ACF3UF_000405"
     CDS             16107..16709
                     /locus_tag="ACF3UF_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFD3670561.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(16768..17874)
                     /locus_tag="ACF3UF_000406"
     CDS             complement(16768..17874)
                     /locus_tag="ACF3UF_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro peptidase family protein"
                     /protein_id="HFD3670562.1"
                     /translation="MNNVKINELRQWMAQHQVELSYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            18084..19085
                     /gene="ccpA"
                     /locus_tag="ACF3UF_000407"
     CDS             18084..19085
                     /gene="ccpA"
                     /locus_tag="ACF3UF_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFD3670563.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(19422..21767)
                     /locus_tag="ACF3UF_000408"
     CDS             complement(19422..21767)
                     /locus_tag="ACF3UF_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFD3670564.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            22046..22948
                     /locus_tag="ACF3UF_000409"
     CDS             22046..22948
                     /locus_tag="ACF3UF_000409"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFD3670565.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            23161..24936
                     /locus_tag="ACF3UF_000410"
     CDS             23161..24936
                     /locus_tag="ACF3UF_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFD3670566.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(25002..26588)
                     /locus_tag="ACF3UF_000411"
     CDS             complement(25002..26588)
                     /locus_tag="ACF3UF_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFD3670567.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            26839..27063
                     /locus_tag="ACF3UF_000412"
     CDS             26839..27063
                     /locus_tag="ACF3UF_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFD3670568.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            27205..28956
                     /locus_tag="ACF3UF_000413"
     CDS             27205..28956
                     /locus_tag="ACF3UF_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFD3670569.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLMLDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            28956..30740
                     /locus_tag="ACF3UF_000414"
     CDS             28956..30740
                     /locus_tag="ACF3UF_000414"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670570.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIITRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTSDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMMKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPIEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVEHGNHETLLAQNGLYADMYKLQSSGI"
     gene            31066..31917
                     /gene="licT"
                     /locus_tag="ACF3UF_000415"
     CDS             31066..31917
                     /gene="licT"
                     /locus_tag="ACF3UF_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFD3670571.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEDLQVHLNDSVYIALTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDKAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRCYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            32012..33898
                     /locus_tag="ACF3UF_000416"
     CDS             32012..33898
                     /locus_tag="ACF3UF_000416"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFD3670572.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVRVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTVARKFKVNEFVGMLLGAALMNPNLSLEVLSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVNYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAMPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKDEAGETDDIQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(33938..34840)
                     /locus_tag="ACF3UF_000417"
     CDS             complement(33938..34840)
                     /locus_tag="ACF3UF_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3670573.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            35071..36474
                     /locus_tag="ACF3UF_000418"
     CDS             35071..36474
                     /locus_tag="ACF3UF_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFD3670574.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLDIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETITSIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETIGRLKEEGIEVQ
                     DELARELSSNTHIMEEV"
     gene            36474..37907
                     /locus_tag="ACF3UF_000419"
     CDS             36474..37907
                     /locus_tag="ACF3UF_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFD3670575.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWDSRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            38052..38978
                     /gene="trxB"
                     /locus_tag="ACF3UF_000420"
     CDS             38052..38978
                     /gene="trxB"
                     /locus_tag="ACF3UF_000420"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFD3670576.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            39193..40920
                     /locus_tag="ACF3UF_000421"
     CDS             39193..40920
                     /locus_tag="ACF3UF_000421"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFD3670577.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EENHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAKKVASYE
                     AIIKKMTEE"
     gene            40935..41285
                     /locus_tag="ACF3UF_000422"
     CDS             40935..41285
                     /locus_tag="ACF3UF_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFD3670578.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(41377..42237)
                     /locus_tag="ACF3UF_000423"
     CDS             complement(41377..42237)
                     /locus_tag="ACF3UF_000423"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFD3670579.1"
                     /translation="MTSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            42329..42757
                     /locus_tag="ACF3UF_000424"
     CDS             42329..42757
                     /locus_tag="ACF3UF_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFD3670580.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            42919..43095
                     /gene="rpsU"
                     /locus_tag="ACF3UF_000425"
     CDS             42919..43095
                     /gene="rpsU"
                     /locus_tag="ACF3UF_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFD3670581.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            43122..43568
                     /locus_tag="ACF3UF_000426"
     CDS             43122..43568
                     /locus_tag="ACF3UF_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFD3670582.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(43722..45101)
                     /gene="brnQ"
                     /locus_tag="ACF3UF_000427"
     CDS             complement(43722..45101)
                     /gene="brnQ"
                     /locus_tag="ACF3UF_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFD3670583.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
     gene            45807..46778
                     /locus_tag="ACF3UF_000428"
     CDS             45807..46778
                     /locus_tag="ACF3UF_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFD3670584.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            46802..48994
                     /locus_tag="ACF3UF_000429"
     CDS             46802..48994
                     /locus_tag="ACF3UF_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFD3670585.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKVNDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            49011..49487
                     /gene="ybeY"
                     /locus_tag="ACF3UF_000430"
     CDS             49011..49487
                     /gene="ybeY"
                     /locus_tag="ACF3UF_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFD3670586.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            49471..49866
                     /locus_tag="ACF3UF_000431"
     CDS             49471..49866
                     /locus_tag="ACF3UF_000431"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3670587.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            49881..50780
                     /gene="era"
                     /locus_tag="ACF3UF_000432"
     CDS             49881..50780
                     /gene="era"
                     /locus_tag="ACF3UF_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFD3670588.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            50923..51735
                     /gene="recO"
                     /locus_tag="ACF3UF_000433"
     CDS             50923..51735
                     /gene="recO"
                     /locus_tag="ACF3UF_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFD3670589.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            52119..53036
                     /gene="glyQ"
                     /locus_tag="ACF3UF_000434"
     CDS             52119..53036
                     /gene="glyQ"
                     /locus_tag="ACF3UF_000434"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFD3670590.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            53038..55113
                     /gene="glyS"
                     /locus_tag="ACF3UF_000435"
     CDS             53038..55113
                     /gene="glyS"
                     /locus_tag="ACF3UF_000435"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFD3670591.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGKASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            55504..56283
                     /locus_tag="ACF3UF_000436"
     CDS             55504..56283
                     /locus_tag="ACF3UF_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670592.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTIVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIDQIRNEKIRAAYATKAQTVAQQMGYSNISY"
     gene            56329..57273
                     /locus_tag="ACF3UF_000437"
     CDS             56329..57273
                     /locus_tag="ACF3UF_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD3670593.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            57289..58068
                     /locus_tag="ACF3UF_000438"
     CDS             57289..58068
                     /locus_tag="ACF3UF_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFD3670594.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKEAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNGKTAPSRRSRSRV"
     gene            58080..58778
                     /locus_tag="ACF3UF_000439"
     CDS             58080..58778
                     /locus_tag="ACF3UF_000439"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFD3670595.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLSNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQIFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLSKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            58806..59570
                     /locus_tag="ACF3UF_000440"
     CDS             58806..59570
                     /locus_tag="ACF3UF_000440"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFD3670596.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFRKNPNYLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIGKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            59583..61400
                     /locus_tag="ACF3UF_000441"
     CDS             59583..61400
                     /locus_tag="ACF3UF_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFD3670597.1"
                     /translation="MFVLTRRRKIATLVVVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            61412..62377
                     /locus_tag="ACF3UF_000442"
     CDS             61412..62377
                     /locus_tag="ACF3UF_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFD3670598.1"
                     /translation="MNILILSCGRRCELVNAFKTALNNNEMEGKIIGADCSELAPALY
                     MCDEKIVLPKVSESNYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVV
                     LVSSEKVIDICENKILTSAFFEQNGFKTPEILNSSEITKFPVFIKPLNGSSSVNTFIV
                     NNEKELLFFSEYIDNPLIQEYILGEEYTIDVCLNFDSTPVSIVPRKRIATRGGEILKG
                     QIIKDRELIETTKKMLEKLNAIGHITIQCIKNEKGIFYLEINARYGGGAPISIKSGAN
                     SPEYIIKMIDSKKNLRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            62370..63065
                     /locus_tag="ACF3UF_000443"
     CDS             62370..63065
                     /locus_tag="ACF3UF_000443"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3670599.1"
                     /translation="MIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIFPATFDEI
                     YRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLENADTLLTE
                     LRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPISYLLLLE
                     KFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFYQADKKIR
                     SLWEIKNFLGVIS"
     gene            63062..64180
                     /locus_tag="ACF3UF_000444"
     CDS             63062..64180
                     /locus_tag="ACF3UF_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFD3670600.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            64170..64790
                     /locus_tag="ACF3UF_000445"
     CDS             64170..64790
                     /locus_tag="ACF3UF_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFD3670601.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            64986..66086
                     /locus_tag="ACF3UF_000446"
     CDS             64986..66086
                     /locus_tag="ACF3UF_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD3670602.1"
                     /translation="MAKYYNKKILIMANNDDGLYRFRGMLIKNLVDQGNEVIVSLPKG
                     KNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNYCNILKKIKPDMVIAYTIKPNIYG
                     GLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFLYRLAAKKSKVIFFENFENMKTFQ
                     TLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVHFLFIGRIMKEKGVDELFEAMKNL
                     YSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYHGYQSDIRPFVERAHCFVLPSWHE
                     GMANTNLESAASGRPIITSDIPGCKEAVIESKSGYLCERKNSCSLYNSMNKFLKLSYE
                     QRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            66093..66488
                     /locus_tag="ACF3UF_000447"
     CDS             66093..66488
                     /locus_tag="ACF3UF_000447"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3670603.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            66485..>67411
                     /locus_tag="ACF3UF_000448"
     CDS             66485..>67411
                     /locus_tag="ACF3UF_000448"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3670604.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKIGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKNKIINLIYPKLIEDEHGE
                     YFSPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDIIQNLSDEYYTRAICKCKYKDNWKG"
BASE COUNT        22434 a        11593 c        14136 g        19248 t
ORIGIN      
        1 ctttaaaaaa caacttgggt attcttaagt tggtagaaga agaggtgaag ccgtgaaaat
       61 tatcgttgac aattttttta cgatcctttt gattatgaat attttgcttt cctttatcat
      121 cgtttttcga gaaagaaagg aaactgctca aacatgggca tgggtgctcg ttttgatgtt
      181 cattccagtt gtaggattta ttttatatat ttttttagga agagggattt ccaaagagaa
      241 aatctttgat ttgaagatcc aagggaaaat cggtaagaac ctggaaattg aagaagacaa
      301 acaggcattg atgcgagggc tttatcctca tccgcctact ggacaagtag atgtgaaaca
      361 attgatctat atgctcacgg tatttgaaag tacgctctat acgactaaaa atgaaatcac
      421 tttatttaca gatggtcgtg aaaaattcga tgcgctgatt gaagatatca agcaggcaga
      481 agaccatatc cacttccagt attatattta tcgcagtgat gcattaggtg aagaagttcg
      541 agatgcattg acagaggcgg caagacgagg ggtaaaagtc agagtccttc ttgatgcatg
      601 gggttccaca caagtttctt ccagcttttt tcagaatttg aaaaaagcag gcggagaagt
      661 cgcatttttc tttcctctat ttgttccgta tattaatcct cggatcaatt atcgcaatca
      721 tcgtaaaatc gtagttattg atgggaaaat cggatataca ggtgggttca atgttggaaa
      781 tgaatatcta ggattggtaa agaaatttgg ttattggcga gacaatcatt tgcgtattta
      841 cggagaagcg gtgtatacct tgcaaaaccg ttttttgatg gactggaatt ctcagcatac
      901 aaaagaagta ggctattctc ccaaattttt tccgtccatt cactctactg gtgatatagc
      961 tgttcaaatc gtgacaagcg gaccagatac cgaacatgaa caaatcaaaa tgacttattt
     1021 gaaaatgatt tcgttagcca aacgggagat attgatccaa acgccttatt acataccgga
     1081 tggatcgatt catgaagcac tgaagttggc tcttctttca ggcgtaaaag ttcatatcca
     1141 aatacctaac aaaccagatc atcttctcgt ttactgggca acgtattctt tcgctgcaga
     1201 gctaatcgag tatggagcaa ggatcgaaac atatgagaat ggatttattc atgcaaagac
     1261 gatgattatc gatggtggca ttgtttcagt tggctcagca aatatcgatg ttcgttcatt
     1321 tcgcttggac tttgaggtca atacactggt ttatgatgaa cgaatggctt cacgtgtaag
     1381 aaaagctttt tttgaagact cgaaaatttc tacgcatctc acaaaagaaa tgtatgaaaa
     1441 ccgaggaata atcatcaaga tgaaagaagg attagcaaga ttgatttcgc cgctccttta
     1501 aaacataaaa aggacatgag aaccatcaac agatggagat ctcgtgtcct tttctaacgg
     1561 ggccatttct gagagtacgt cagaaatgga gaaagcgtct cgcatgagcg aaattaactt
     1621 tggggtatct cttgtttttt ggggaaagca agaaataagc taatatatgc tattaaaaga
     1681 gacacatttc aaagccagta tagcatagaa acttttaatg agatagtttt ttttacaatt
     1741 atgagaattt attttgttat ttaatgattt tgattcgttt tcatcaagta atgaaaatga
     1801 taaaataaac atactttagg attaaaggag atttctaatg aaaaaactta aattattctt
     1861 accaataata ggattagcta ttcttttatc aggctgttca aagtggattg atcgaggaga
     1921 atccattacg gctgttggct cttctgcttt acagccttta gtagaaacag ttgctgaaac
     1981 ttaccagaca gaaaatcctg gaaaattcat caatgtacaa gggggcggaa gcggaactgg
     2041 tttgtctcaa gtacagtcag gagcagtcga catcggaaac tctgatttgt ttgcggaaga
     2101 aaaatcgggg atcgatgcct cagcattagt cgatcatcga gtagcagttg ttgggatcac
     2161 tcctattgtg aacaaggata ttggcgtaaa agacatcagt atggaaaacc tgaaaaaact
     2221 atttacaggc gagatcaaaa actggagtga agtcggtgga aaagatcagc cagtagttat
     2281 attgaaccgc gcttcaggaa gcggaacccg tagcacgttt gaaaaatggg tattggacgg
     2341 agaaacagct gttcaggcac aagaacaaga ttcaagcgga atggtgcgcc agatcgttgc
     2401 cgacacaccc ggtgcaatca gctatgttgc tttttcttat gtttccgatg atgtagatac
     2461 gttgaatgtt aacggtgtag aaccgacaga tgaaaatgtg acaacgaaca aatggacgat
     2521 ttgggcatat gagcatatgt acacaagaga tcatccaaaa aaactgacaa aagaattttt
     2581 agactatatc ttatctgatg aagtacaaga taacatcgtt ggagaactag gttatatccc
     2641 tgtttctcat atgaaagtcg aacgtgattg gcaaggaaat atcgttaaag agtaatcttt
     2701 acacaaaatt tacaaactta gctaaacttt tacatgttat taaaaccaaa ttgatgttca
     2761 atttgtacac tgagtgagta tgttaaacct gattaagggg gagtcatctg tggaagatgt
     2821 gaaaaaagta ttattaacaa aatcaaaacg ttcaaaaatg gaacagcgtg gaaaattcat
     2881 cagtttttta tgtatcgcgc tgatcgtgtt ggttgtatta tctatttttt attttgtagc
     2941 tagtaaagga ttggccacct tttttactga taagatcaat gtatttgatt ttctgtttgg
     3001 tacagattgg aatccaagcc aaatcggagc aaatgggaaa ccaatggtag gggcattgcc
     3061 tatgatcaca ggttcgttta ttgtgacctt tttatctgct atcgttgcca cgccatttgc
     3121 cattggtgca gcagtattca tgacggagat ctctcctaaa aacggaacga agatcttaca
     3181 gccggtcatc gagctgcttg taggtattcc ttctgtcgtt tatggtttta tcggtttatc
     3241 agttatcgtg ccttttgtca gaagtatttt tggcgggact gggtttggta tcttagctgg
     3301 tacatttgtg ttgttcgtta tgatcttgcc gactgtcaca acgatgactg ttgatgcatt
     3361 aaaggcagtg ccacggcact atcgggaagc ttcattagcg cttggtgcca caagatggca
     3421 aacaatctac aaagtcgtgc tacgagcagc cgtgcccggg attttaacag cagtcgtttt
     3481 tggtatggct cgtgcgtttg gtgaagcctt agctatccaa atggtcatcg gtaatgcagc
     3541 attgatgcca acaggtctta ctactcctgc ttctacattg acgtccatct taacaatggg
     3601 aatcggaaat acaatcatgg gaacagttga aaataatgtg ttatggtcat tagcgctgat
     3661 cttgctattg atgtcattat tctttaatat cgtgatccgt atgattggga agaaaggaga
     3721 gctgaaataa tgaacgcaaa acgctcagat aaaattgcta caggtgtttt atatatagtt
     3781 tcggggatca tcgtattgat tttagcagct ttactacttt atatcttagt tcggggaata
     3841 ccgcacattt catggtcctt cttgaccgaa ccttccaaag cctaccaaga aggcggtgga
     3901 atcgggatcc agctatttaa ctcgatttat ttgcttttga tcacgatgat catcagtttt
     3961 cctatttctt taggtgcggg tatctatctt tcagaatatg ctggaaaaaa ctggctaaca
     4021 gatgtgattc gcacgtcgat tgaaatcttg agctcgttgc cttctgtcgt tgtcggttta
     4081 ttcggtttct tggttttcgt tattcaattc cagtatggtt tctcgattat ttctggtgca
     4141 ttggctttga ctgtattcaa cttgcctctt ttgactagaa cagttgagga gtctttacaa
     4201 gcggtccatt acacacaacg agaagcagga ttggccttag gtttgtcacg ctgggaaaca
     4261 gtgataaaag tggtggttcc agaagcgaca ccagggattt tgactggtgt gatcctaagt
     4321 tctggaagaa tttttggtga agcagctgca ttgatctata cggctggaca aagtgcacct
     4381 gcgttagatt ttacgaactg gaatccatta agtgtttcaa gcccgatcag cattttccgt
     4441 caagctgaaa cattagctgt ccatatttgg aagatcaata cagaaggcac gatgcctgat
     4501 ggtgtttctg tttcggctgg cgcttctgcc gtgttgatta ttgctgtttt actgttcaac
     4561 ttcggcgctc gtgcgattgg caaacgatta taccgaaaaa tgacttcagc ctaaggagaa
     4621 gaagcaaaat gaaaaaatat aactggaatg aaacaaatgt catcaccatg ccaaaagaga
     4681 aagaagtagc actatatacg gatgatctac atgtctggta tggcgacaat gaagcaatca
     4741 aaggagtgga tctggaattt gaaaaaaata agatcactgc actgattggt ccttccggct
     4801 gcggaaaatc tacgtatctt cgttcgttga atcgaatgaa tgatgggatc gctaatacga
     4861 aaatcactgg gaaaatcatg tatcaaggcg tagatattaa tgcgcctcaa gtggatgttt
     4921 atgagatgcg caaacggatt ggcatggttt ttcaacgtcc taatccgttc agcaagtcga
     4981 tttatgacaa tattacattt gctttgaaac agcacggcga aaaaaacaaa aagaaattag
     5041 atgaaatcgt tgaaacaagc ttgaaacaag ctgccttgtg ggaccaagta aaagacagct
     5101 tggacaaaag tgccttggct ttatctggcg ggcaacagca acgtttatgt attgctcgtg
     5161 cgatcgcgat gaaacctgat atcttgctgc tagacgagcc ggcaagtgct ttggacccta
     5221 tttcgacagg aacggttgaa gaaacacttg taaacttgaa agaagactat acgatcatca
     5281 tcgtgacgca taacatgcaa caagcagctc gtatcagcga ctatactgcc tttttctatt
     5341 taggaaaagt aatggaatat gacaaaacta acaagatatt taccagacca aaaattcagg
     5401 caaccgaaga ttatgtgtcc ggtcattttg gttaagacgg aggcctcaac atgacaaaag
     5461 agattatttc atctaaagat cttcatctgt attatggaaa gaaagaagca ctaaaaggga
     5521 tcgatctaag cttcaatcaa ggggaaatca ctgcgatgat cggtccttct ggttgcggaa
     5581 aatccactta tctgcgttct ttgaaccgga tgaatgacct gattccgaat gtaacgatca
     5641 ccggaagtgt tttatataaa gacaaagaca tctatggtcc aaaaacagat gttgttgaac
     5701 taagaaaaga aatcggcatg gtattccagc agccaaaccc atttcctttt tctatctatg
     5761 aaaatgtcat ctatggattg aaattaaaag gggaaaaaga taaaaaagtc cttgatcaag
     5821 tagttgaaga aagcctgaag gcagcgtctg tttgggatga tgtgaaagac aaattgcata
     5881 aaagtgcttt atctttatcc ggtgggcagc agcagcgtgt atgtatcgca cgtgttttgg
     5941 cagttaatcc ggaaatcatc ttattggatg aaccaacaag tgcgcttgat cctgtttcta
     6001 ctgggaaaat cgaaagtatg ctgttagaat taagagagcg gtatacgatg atcatcgtga
     6061 cccataatat gtctcaagct tcacgtattt cagataagac ggcattcttt ttagatggtc
     6121 acttgatcga atacaatgat acgaagaaga tattcatgaa tccagaaaaa caagagacag
     6181 aagattatat ttcaggtcga tttggataag gaggaaacgg aatgctacgt acacaatttg
     6241 aagaagaatt gctgaatctc cataatcagt tctacgaaat ggggatgatg gtgagcagcg
     6301 ccgtgcacaa gtcagttcgt gcatacatca aacacgataa aatcttagcc caagaagtta
     6361 tcgaaaacga tataaatatc aataacatgg aaacacgctt ggagaagaaa agttttgaaa
     6421 tgatcgcatt gcaacagcca gttacaactg atttgcgtat gatcattacg gtcatgaaag
     6481 ctagctcgga tttagaacgt atggccgatc atgcggtgtc tgttgctaaa tccacgattc
     6541 gcgtaaaagg gcagacgaga ataccggaaa tcgaaaaaga gatctccgat atgtccgatt
     6601 atgtgaaaaa aatggtggac aacgtcctag ttgcttatgt caaaacagac gaaaaagacg
     6661 cacgtacgat cgccaatatg gatcaaagag tcaatgacta tttcaatcga atctataatg
     6721 caacaatcaa aaatatgcag gaaaatcctg agacagtcat cagtggaaca gactacttga
     6781 atgttgccag ttatctagaa cggatcggag actatgtgac aaacatctgt gaatggatcg
     6841 tctacttggc tacagggaaa atcactgagt taaatacgaa ccacaatgag attttctaaa
     6901 ctgaagctgt gattatgccg tttgtttagg aaaagaggtt gtgaaatcag cggttgtgaa
     6961 aaagctgttc tgcatcaagt aataagaaca gtcaaacaaa aaatagctcc tcatattttt
     7021 cgtttggctg gacttattac cgcagatgca agcttttgaa caccgtttat tcgggaaagg
     7081 gtttgtgaca aaacatgtca caaacccttt tcatcatttc atagaaagga taaagaatgc
     7141 aaaaaaaaat tagcatcatc actatatttt ttatttgtgt gcttacttca tgggttattc
     7201 agcatcaagc cgctttatat gaagtacctg tcatcgagat agaaaaagta cgaataaaag
     7261 aggatcatca attgattaca ggaaaactga tgaacacgga tcaaaaagga gaatcgattt
     7321 atttatcggt tccttatcaa aaaaatcaaa tagaaacagc aaatataaaa gcgagacaaa
     7381 tgtatctagt ccaaatgcat ggagatgaat ggcagctagt agcaaaaaaa aatgatggct
     7441 ggcttttctt cttcacaagt atcttcattg gcgccatgtt gcttattggt ggaaaacagg
     7501 gtctatttgc tttaggaagt ctcatcatca atatcgtttt acttttactt ttgttgctca
     7561 tctttactaa aacagaaggg atttctctat taaatatatc tatcctgttc gtcgttatag
     7621 ggatgattat tagcatattg gctttagatg gatggaatag aagcagtata atcaaaattt
     7681 cagctgcagt tacgagtgtt tttttagcat tttttatttg tcttttgaca atgaatcatt
     7741 ggaaagacca aggactgcgc tatgaggaac tgaattatct gacacgaccg tatcgttctg
     7801 tttttctttc tagcgtactg attggaacag ctggaggaac actcgatacc gttatcacag
     7861 tcattgcgac attagaagaa ttgactaagc gacaaccaga aataacagcg aaacagttat
     7921 ggctttcagg aaggcaagtg ggtcgagatg tgattggctc gatgaccaat atccttttgt
     7981 tcgtctatat cagtgggtca gttccatcgc ttcttttata tttaggaaat caatggtcgt
     8041 tcaaagaaac gatagaacag catttatcat tggaattttt acgcgtcatt gctggcagct
     8101 taggaatagt attatcgatc cctatctcgg tcctcttttt tctgactgta aggaggctga
     8161 aacgatgaat gtacttatta tacttgttgg gattttagca atcagcgtgc tacttattgg
     8221 cggtacgcaa ggtatgtata ttcttttagg cttattcatc aatttaggga tctttttcct
     8281 gttgttattc ggttatcatc agaagtggcc gatactggca ttgtcggtca taggattttt
     8341 attgattgct gtggttatct tattttttat caacggttat aatctaaaaa tgcgtgcagc
     8401 ttttgtgagt atactgatct ttttattttg tttcctacta ttgcttccta tcactgattt
     8461 tttagcaatc caaggtttta catcggtaga actagaagaa ttatctggct tagataagac
     8521 tttagcgatt gattttagat tacttacgag atcgttgctt ctgattagtc ttagtggtgc
     8581 tgttttagat gcgagtgtag caatttctag tgggacattc gaagtatatc aggcaaatcc
     8641 gcaattatct ttttaccaat tgcgccattc tagtttcgct attgctaaaa aaatattggc
     8701 gtcaacagta atgacacttc tttttgcatt catgggaagt tctttagcgt tgatcctctg
     8761 gtttattgat ttagacattc cttttcagca agtgatcaat gaaaaatcat ttgttctaga
     8821 atatacgatg gctattctta ccacattgtc cgcactactt gttcttcctt taacctgcgt
     8881 gactacagca tatctcttta caaaaaagaa agaacaactc aagatggagt aaaagttaca
     8941 acttaagtcc tatgacattt ttactgaatc agtgcataat atggatgtaa ggaaaagctt
     9001 gcaaacaatt ttgcttaagg aggcaatttc catgaaagaa agagaacgta ttttagattt
     9061 agtgaaaaaa ggaatccttt cgactgaaga aggcttagat ttattagaaa gcatggcaac
     9121 tgaaaaagac gaaaagcaaa tcaaaaaaga agcagacaag gtaactgcta gtcataaaga
     9181 aaaagatcag gcaagtcaat tgatcgataa acttgaaaac ggcgaagaag aaatttctga
     9241 gccagttgat ccaaaggaaa gagaaagaca agatcaagaa aacttagaaa agatcttaga
     9301 tgaactagca actgaagcga ataaaacttc ggcgcgtcta gatgaagtaa atgctcaatt
     9361 cgctgacaat aaggcagcac gcaatgagaa acaggaagca ttgatgcagc tgaatacaaa
     9421 agaagaatta ggcgagttga cagaagaaga attagcacag cgtcagacgt tagaagcaga
     9481 aatcaaagaa ttagaagcta gtggcgatac actgttagaa gaacaattga aattagaagc
     9541 agaattaaaa gatatccgta agaatcaatg gtctgagaaa aaagaaacgt ttactgataa
     9601 gtttgaattg ccagatgatt ggaaagatca agcaacagat acactgaatc aagtaggcga
     9661 aaaaatgtca gaagctggat cacagttagg caaattcttg aagaaaacat tccaaactgt
     9721 ttcagaaaca gtgaatgaca acatggaatg gaaagatgtc agcttacgtg tccctgggat
     9781 tgcgacaacg aaatttgagc atgaatttta ctatgaagct cctgcagcaa gtatccttga
     9841 tatcaaggca gcaaacggaa acgtgacgtt aaaaacgtgg gacagcaacg atgtgaaagt
     9901 tgaagctaag atcaaacttt acggaaaaat gggtgctgaa ccatttgaag cattctctga
     9961 acggagccag attgaggtta atgaagatca tatctccttc caaattccaa ataaacgtgt
    10021 gcgtgcagac cttgttttct acttacctaa acgagtatac gaccacgcag ctattaaact
    10081 tctaaatggc aacatcatga ttgaaacatt ggaagctaaa gatatttata caaaatctac
    10141 gaatggtaac atcatcgtgg accaattaac tgcaacgatg ctggaagtag aaggtgtaaa
    10201 cggcaatatc gatattcgaa acgggaacat cttagattct attatcgaaa cagtaaatgg
    10261 tacagtgaca tttggtgcga cagcagaaaa cctttctgtg tctttggtaa atggtgatgt
    10321 acgtcttacg attaaagaag ataatttgaa aaaagtagaa gcaagttcag tgaacggaaa
    10381 tgtcaaagtc gctttaccag atggcatcgg tttggaagga catgctaaaa caagtcttgg
    10441 aagtatcaac agccgtctgt ccaattacga agtagttcgt gagaaaaaag aacggacaaa
    10501 ccaaatgttg caattccgtc gtgtttcaga tggtgaaatc gcgcaagtgc aactttcaac
    10561 gacaacagga agtatctatt taaaagatac agataaataa agaggttgtg aaagagatgt
    10621 tcagccttga gcaataagaa gcgattttgt aaaatagctt cccctatttt acaaaattgt
    10681 gccttattgc cgatagtcta tctcttgaac accgtttacc aagagattat gaacctgcca
    10741 attatcgccg agtcacaagg aataatttca gaaaaagctc gtcacgtttt atgaatatgg
    10801 taatttgtga ccgagaattt tgcagaaaga caccgattaa gaagaaggtt gtcacaacga
    10861 ttttcttcat ttaaaatagt agaacagagg tgagacatga tgaaaaaaaa gttgacaaaa
    10921 tctaataaaa atgttgtttt gacagggact ttagcaggaa taggagaata catcgggatt
    10981 gatccgactg ttatccgtgt gctttatgta ttcctgagct tagttgcttt tggaagtcca
    11041 attattttat acattttatt agctttgatt atcccatctg cgcgttctgc acgaacaaac
    11101 tatggacata acaatgcata ttatgaaaaa aacaattatc gtgaacaaac tcgtgaacaa
    11161 acaaaaaaac gcaaagaagc ggaaaaaatc gatgatgacg aatggagtga cttttaatgt
    11221 cgtactttca acgtatttta gttaatacgt taacattcat atcattggct gttctttttc
    11281 ctgcgatggt ccatgtgagc agtatttgga cggccgttct tgccagcttc gtattgtctg
    11341 tgttgaatat gtttgtcaaa ccgattttga cgatactgtc cctgcccttt acattagtca
    11401 cattgggatt gtttacgttt gttatcaatg cagcgattct taaaatgacc tccttttttg
    11461 tgggagcaga acattttagt ttttcttcat tcggtgcagc gttgttagta gctatcttga
    11521 tgtcgcttgt caatgtaatt gtcagcgaac ataacagtag aaaataaaag aaagctgtgc
    11581 cgaactatcg gcgcagtttt tttatttaga atcaggaatg cgttttctat tacattggta
    11641 attaaataaa aacgtttttt ttaattggta gtacttttgg ctagacaatg ataaaatgat
    11701 agagaacact ctaatagaaa tgaggtagca tgaatgtcag aagttgtaaa agttagccaa
    11761 ttagtgaaaa aattatcttt ggaaatcgtg acaggcgacg agaaaagctt agaccgtgtc
    11821 atcgtaactg gggacatctc acgcccagga ctagagttga ctggttattt taattattat
    11881 tcccataatc gtttacagct atttggcagt aaagaaatca gttttgcgga acggatgatc
    11941 ccagaagagc gtttgatcat catgagaaga ttatgtagtg aagatatgcc cgcatttatt
    12001 atttcaagag gattaccagc tccagaagaa atgatccagg cagcaaatga aaatgggata
    12061 gctgtactgc gttctcccat ctcaacttct cgtttattag gagaattatc cagttattta
    12121 gatggtcgcc ttgcccctcg aacaagtgtc cacggtgttt tagtggatgt ttacggatta
    12181 ggtgtactga ttcaaggtga cagtgggata ggaaaaagtg aaacagcgtt ggagttgatc
    12241 aaacgcggcc atcgattgat cgcagacgat cgagtagatg tttatcagca agatgaatta
    12301 acggtgatcg gagaaccgcc taaaatcctg gaacatctga ttgaaatccg aggaatcggg
    12361 atcattgatg taatgaatct ttttggtgcg agtgcggtac gtggctctat gcaagtccag
    12421 ttggctgttt atctggaagc atgggcaaaa gataagaaat acgaccgtct gggctctgaa
    12481 gacacgaccg ttgaaatcgc ggaagtgggc attccacaaa taaaaatccc tgtcaaaaca
    12541 ggacgaaacg ttgcaatcat cattgaagta gccgcgatga atttccgtgc acgtacaatg
    12601 ggctttgacg caacgaaaac atttgaagaa agattaagtc gcttgattga agaaaactca
    12661 ggcaacgact agcaaggagt gacaatatgt tagcacaaat caatcgagtt gcttttgagc
    12721 ttgtagggat tcctatctac tggtatgcat tgatcatcgt atcaggtatc attatcgcta
    12781 tgtggcttag cagcagagag gctgttcggg taggattaaa agcagatgat gtgacagatt
    12841 ttatgttgtg gggattgcct atctccatta ttggcgctcg cttatattat gttttatttg
    12901 atcttcccca gtatatagct gatccaatcc aaatattcaa tatccgttca ggaggcttag
    12961 ctatttatgg cggactgatt gcaggcgcga tcacgctgta tttttttact aaatatcatt
    13021 ttatttcttt gtggactttt ttagatatcg ctgcaccaag tgtattatta gcacaggcaa
    13081 tcggtcgttg gggaaatttc atgaaccacg aagcatatgg accagacacg acgcgaagct
    13141 tcttagaaag tctgcattta ccgcaattca tcattgataa tatgtatatc gaagggatct
    13201 atcgtcaacc aacatttctt tatgaatcac tttggagttt gattggattt attttgcttt
    13261 tgtttttacg aaagaaacca caccttttga aaaaaggcga agtcctttta tgttatctaa
    13321 tgtggtatag tttcgggcgt ttctttattg aaggattacg tacagacagt ctttactttt
    13381 taggtgtgat ccgtatttct caattattat ctgctgtgtt atttgtcggt acattgattc
    13441 tatttatttg gcgcagaaaa aaaggaaatt taccggatta tgaccgctca ttaggaaaaa
    13501 atcaacaaat tatctgattt ttagagcgtt aaaaatgaaa aaaatttcag gagtggtaaa
    13561 atgaattata gagtagcggt tttaggacca ggctcttggg gtactgcttt ggcacaagtc
    13621 ctcgccgaaa acggacatga cgttcggatt tggggacatc gtgcttcaca agtagaagaa
    13681 atcaacaccc aacacacgaa tcaacgttat ttaccagatc attatctacc cgattccatc
    13741 caagcattca ccaatatgga agatgcagta aaagacgcag atgcggtgct attcgtcatt
    13801 ccaacgaaag caatacgttc tgttgcaaaa gaactagtgc ctaaattgaa tacaaagcca
    13861 gtgatcatcc atgcaagtaa aggattagaa cagggaacac ataaaaggat ctctgacatc
    13921 ttgttagagg aaatcccagc agaaaaaaga aaagctgttg ttgttctttc tggaccaagc
    13981 catgcagaag aagtagcaaa acatgacatc actacgatca cagctgcaag tacagatgca
    14041 aaagcagcaa aatatgtaca agagctgttc atgaataatt attttcggat ctataccaat
    14101 cctgatgtga tcggtgtaga gatgggggca gctttgaaaa atattattgc tattggtgct
    14161 ggcgctattc acggcttagg gtttggcgat aatgcaaagg cagcaatcat gacgcgcgga
    14221 ttagctgaga tcagccgttt aggtgtagca atgggtgcca acccgctgac ctttatcgga
    14281 ttaagcggaa taggcgatct agtcgttact tgcacaagtg ttcattctag gaactggcgc
    14341 gcaggcaact tgttaggaca agggcagccc ctagaagagg tgctagccaa tatgggaatg
    14401 gtcgttgaag gtgtgaatac tacccaagca gcgatggaac tagcccaaat gatggaaatc
    14461 gaaatgccca tcactcaaac aatctatgaa gtgctgtatg aacaaaaaga aatcaaaaca
    14521 gccgcaaaag aaatcatgtt acgtgatgga aaaaaagaaa atgaattctc attaacaatt
    14581 ttttgaagga gcgaatgtat atgaaagtta aaaaagcagt tattccagca gcaggattag
    14641 gaacaagatt tttaccagca acaaaagcta tggcaaagga aatgttgcca attgttgata
    14701 aaccaacaat ccagttcatc gttgaagaag cgttgaaatc aggtatcgaa gacatcttga
    14761 tcgttacagg aaaagctaaa cgaccaatcg aagatcactt tgattcaaat attgaattag
    14821 aaacaaacct aagtgaaaaa ggaaagaccg aattattgaa attagtagaa gaaacgacag
    14881 atgtcaactt gcatttcatc cgtcaatctc atccaaaggg tttaggacat gccgttcttc
    14941 aagcaagagc ctttattgga aatgaaccat ttgtcgttat gctaggcgat gatataatgg
    15001 aagacgaagt accattgaca cagcaattaa tcgatgatta cgaacgtact catgcttcta
    15061 cgatcgccgt tatgcaagtt cctcatgatg aaacttcaaa atacggaatt atcaatccag
    15121 gagaagtatt ggaagatggg ttatacaatg tcaaaaactt tgttgaaaaa ccagatccaa
    15181 gcaaagcacc aagtgattta gctattattg gacgttactt attgactcca gaaatttttg
    15241 atgtattgtc cgagcaacaa ccaggagccg gaaatgaaat ccaactaact gacgcaatcg
    15301 atacattgaa taaaacacaa cgcgtatttg cccgtaaatt cacaggtaaa cgttacgatg
    15361 tcggtgacaa atttggtttt atgaaaacaa gtattgaata tggtctaaca catccagaag
    15421 taggtgcacc tttacgtgag tacatcctgt ctttaggtaa aacattagaa gcagaaggaa
    15481 gcaagatcga tcataatcca aaaggaataa cagaaatcaa agaagaaaag aaaaaataac
    15541 ccttttttct aacgagcttc agctgctaat tgaataaaaa gtagttgaag ctcgttttta
    15601 tttgtttaaa aaacacgaaa atgctatcct tatagaaaag agagacaaga agggagtttg
    15661 atcatgtcag gaggagaaat tgcaggattg atcgcagcaa tcgcctttgc gatacttgtc
    15721 gtttttatcg ttcgtgtgtt gttgcaagtt tctaaaactt tagaaaaagt agatcagact
    15781 gtagcagaag caaatacgac gatcgaaatc gtcacaaaag acgtagatct tttgtctaga
    15841 caagtagaag gcttactggt caaaagtaat gaactgctct tggatatcaa tggaaaagtc
    15901 gcaacgatcg atccattgtt cacagcagtt gctgatttaa gtgaaagtgt atcagaactt
    15961 aatcattcta gtaaaaacat cgcgacgaaa gtcggcggaa tcggtaaaac gacagctaaa
    16021 gcgacggttg ccggaaaagt cggtgggaca gcgatgaaat tttttaaaaa caaaaaacat
    16081 actgaaacga caggaggaaa ataaaaatgg ctaaaaaagg tggattttta ttaggtgcag
    16141 tagtcggagg cacagccgca gcaatcgccg cgttattgtt agcaccaaaa tctggtaaag
    16201 aacttcggga tgaattagct gcccaagcgg atgatttgat ggatatggct tcagattaca
    16261 cagatatggc gaaagaaaaa tcgactgagt taacaggtat tgcaaaagaa aaagcgcaag
    16321 atctttctca acaagcaggt gatctagcag gtagtgtcaa acaaaaagta agtgaatcag
    16381 cagatgaagc aggaagtgaa tctgacgata tcttgttaaa tcttaaagaa caatcagctg
    16441 acttatctaa tcgtttcaaa aaaacggcag aagatatgaa aaaacctgca gatgaattag
    16501 gaagtattgc taaagatact tcagaagata tcatgattga tgtaaaagac gctgctggta
    16561 aagcaggaga tactgtcaat gaaggaatgt cagaagcaaa accagttgca gatgactcaa
    16621 aagaaatgat gaaaatggca aaagaagatg cgaaagaagc taaaaaagaa ataaaagata
    16681 caatgacaga ttcatctaca aatcactaaa atcacaaatt tatagaataa aaaggtggga
    16741 gcggactagc tctcaccttt tttactctta tttttctaaa acaagtaatt cttttggtgt
    16801 agtcgtgaat ggcacacagc catcgcttgt cacatataca cagtcttcga tacgtacccc
    16861 tactttttca ggaatataga ttcctggttc aagagagaag cacatccctt cttcgattac
    16921 taagtcattt ccttctacaa gggaagggaa ttcgtggacg gttgttccga tcccgtgacc
    16981 taaacggtga ttgaaatatt cgccgtagcc atagctgttg atcacgtttc gtgcgatttg
    17041 atcaagttca cctgctgtca cacctggacg gacggcttct tgtgcggcaa gctgtgcttc
    17101 aagagtgatg ttgtagattt tttcttggaa gtcggttggt ttttgataag caattgtacg
    17161 agtagcatca ctgcaatagc cattccaaac aacgccaaga tcgaataaca caagttcatt
    17221 cggtgaaatc ttcgtatttc ctggtgtacc atgagggctt gcagcatttg ctcctgcaag
    17281 gactaatgtg tcgaaagaca tttgtgaaac accttgtttt ttcaattggt attcaatttc
    17341 tgcaatgatc gcttgttcag tcacgccttc tttcactgct ttaaagccaa tctcaaatgc
    17401 aacatcggcc catttaccag cttcgatcag tttgtctttt tcctctagag ttttgatcag
    17461 ttgtagacgt tggatgatgg aagttagatc agtgtaagaa tccgttcccg tcaagatatc
    17521 agagatagca tcgaagcgct cgacagtcaa ggcgttcttt tcaatcccta cattgccagg
    17581 ctgaccatag cgagcacgaa gttcttttcc gatgatctcc caagggtttt cgctgtctaa
    17641 atagccacgg acatcatacg cccaactact gttttgagca tcttcaactt ccaaagcagg
    17701 agtgaaaagg aaaggatctt gttcaagagg gataaaaaga gctagtacac gctcatgagg
    17761 atcactttcg tatccggaaa agtaagcgat gtggccaggg tcgctgatat aagacaattc
    17821 gacttggtgt tgtgccatcc attgacgtag ttcattgatt tttacgttat tcatttggca
    17881 acctactttc taaattaatt ttgtattcaa taattgtacc actgatttat taaaagacca
    17941 acgttctaaa aactgaaaaa agtaaaaatt ttcatgaaaa cagagataaa acggttgcaa
    18001 ttcttgagat tatttgatat tctattttag aaatgtaaga cgtattttca gaaaacatat
    18061 aaaatatgaa taggagaaca caaatggaaa agcaaacaat cactatctat gatgtagcga
    18121 gagaggcaaa tgtttcgatg gctactgttt cacgtgtcgt aaatggcaat ccaaacgtta
    18181 aaccagcaac aagaaaaaaa gtcttggaag ttatcgatcg cttggattat cgtccaaacg
    18241 cagttgcgcg tggcttggca agtaagaaaa caacaacagt tggtgtaatc atccctgatg
    18301 tcagcaatat gttctttgct tctttagcac gtggtatcga tgatgtggca acaatgtaca
    18361 aatacaatat tatcttagca aattcagatg gcaacgacca aaaagaagtc aatgtattga
    18421 ataacttact ggctaagcaa gtggacggcg tgatcttcat gggtcaccat atcacagacg
    18481 aaatccgtgg agaattttca cgttcaaaaa ctcctgttgt attagctggc tctattgatc
    18541 cagatgaaca agtaggtagc gtaaacattg attatgtatc cgcaacaaaa gatgcagtaa
    18601 acaaattggc aaaaagcggc aataaaaaaa tcgcttttgt cagtggtgcg ttgatcgatc
    18661 ccatcaatgg acaaaatcgt ctgaaaggct ataaagaagc attaagcgaa aataacctac
    18721 catatagcga aggattgatc tttgaagcac aatacaactt caaagatggt ctatctctag
    18781 tcgatcggat ccataatagc ggtgcaacag ctgtctatgt ttcagatgat gaattagcca
    18841 tcggtatttt ggatggttta ttagaccgtg gcgtgaaagt accggaagaa ttcgaaatca
    18901 tcacaagtaa caattcacta ctgacagaag tagctcgtcc tcgtttaaca agtatcacac
    18961 aaccattata cgatttaggg gcggtatcta tgcgcctatt gacgaaaatg atgaataaag
    19021 aagaagtcga agaaaaaacg attatcttgc cttatggaat cgaagaaaaa ggatctacaa
    19081 aataataaaa ggacaaccat tcagaggttg tgtgcctgcc gtttaactct gcgttacaag
    19141 gagcaatttc aaaaaacagc atctcatgtt tgatgaatat tgtgactcgt gattcggagt
    19201 tggcaggaga acaccgttta tttgggaaaa ggggttatga caaaattttg ttataatcct
    19261 ttttttgtgt cttaaaaaag agagaaagtg gttgaaatta catttatcgt atataaaaca
    19321 atccgtgtat agatgctgca ttttgttcac caccatcaaa aaaataaggg actgtgacaa
    19381 tactattgtc acaatccctt attactgtgt attctattaa atcaatcatc tttctcatct
    19441 gattctttag ttgcttgatt cgctcttgca taagctgaag cggtgttcca gtaatctgta
    19501 tagttttcat cggtaccgcc aacgccaaat ttaaaggcgc ttttcttcgg tccatttttc
    19561 gcccatagcg attcaactgt ttttcctggt gtttggatgg attttttatt gacagtaact
    19621 tttccaggtg tttgaccagt aaatccagat acttttttct tcatcacatc agatgataat
    19681 tcgaatttct catcagtgcc aaaaatgtca ggttttgctt ggtaagcttg attgatcaga
    19741 ttggcaagat aattagccga acgtatcctt gctttgctgt ccattccagt attgtcatcg
    19801 tgccctgccc agctactgat ggtaatagac ggagtagaga caattagcca tgaatctcgg
    19861 tattcattgg tagaaccagt ttttccgacc caatctgctt ttcctagatt tccgtttaag
    19921 cttgagatgg catctttgaa tggtgtagtg atttttgcat tgatcacact acgcatcatg
    19981 tcattcatga tcgatgccgt tgcttccgaa tagatccgga cagagttgct ttcgtgttta
    20041 taaattacat ttcctgcgtt atctgtgatg gaatcgatga tatagccttc ttcatagacg
    20101 ccgccgtttg ctaaagcctg aaatccgttg gtctgttgaa gcgtcgtgac atctactgta
    20161 cctaaaggag cagattcaac gccccaattg tcatttgccg ggtagttcat ctttgccaag
    20221 tagtgctcgt aagcatattg tttcgatcca ccggaattca acacatcttg atataagtga
    20281 taagccggga tattgttgga ccattctagt gactcacgga cggtttggaa ggtgttcgat
    20341 ccttcgttag tagcattgac gattttctcg ccagcatttt ctccttcttg ccaagttgtt
    20401 gcataatctg atacacggga ttctgatccg ataagcccca tgtcgattgc aggtccataa
    20461 acaagaactg gtttgattga tgagccagct tgacgttctg tatcgaaggc atggttattt
    20521 tgattctgac tgtaattccg tccgccaacg aatccgtaga tgcggccagt tctgttatcc
    20581 atcaatacat ttccggtttc tacttgactg ccagcaccat catctaacat gtatccataa
    20641 ttttcaacgc cattttgcaa tgcagcatag acatctttat cgattgtcga atggattgta
    20701 tatcctttat tttggatcgt ttgctgtgcc ttttgataat aagcgtcact gaccgatgaa
    20761 tcagacatat cagcgttgtc tttttcagcc aattgttgtg caatgattct tgttgcttca
    20821 ttcatcacag tataatacaa gaattctctg tcagtctgtt ctgcgatttg ttgtggtaga
    20881 aagtcttttg taaggtcata ggcttttgct tcttcgtatt gttctttcgt aatttggcct
    20941 tcacgataca tactgaataa aacaaaatct tttctggcaa ggccggcaga aagatcttct
    21001 tttagcgcgc ctgtgttcgt gtatggacta tacgtgatcg ggctttgggg taatccagcg
    21061 atataagcag cttgcggcag cgtcacatct tttgcatcta caccaaagat tccttttgca
    21121 gcttcctgga ctccagcaat gttttgtccc ttattattac gaccaaatgg tgagacattc
    21181 aaatacgtag caatgatctc atcttttgaa aagtattttt ctacttgtgc agaaagaatg
    21241 atctcgtttg ctttacgttt gaatgttgtt tcatctgtaa ggatctgctg tttgactaat
    21301 tgctgtgtca aagttgatcc accagaagag ccaataccag tagcttcaga tactaatgct
    21361 cgtaaaacag ctttaggaac gtaaccttgg tgtttatcga agtattcatc ctctgtgctg
    21421 ataattgcag ttttcaataa aggtgaaatc ttatcagatg aaatagtcgt gcgcatcaga
    21481 tctgtctgga tttttgatat ctctgtatta tctgcataaa caatctttga cgtttctgta
    21541 atgtttccta gttctgtctg cagtgctttt ttagtcggca attgtgtgtc ttcgacgaga
    21601 taggcaaaat agccagcgcc tattccaata cctagagctg cgaacatcaa aagaagaaca
    21661 gtaataaaaa cagtcaatga ttgaaaaact ctaaaaataa tcttaggaac aaaccatttt
    21721 tctttttttc ttctattctg tttttttcga gtatttttgc gtggcaaaag ggtcacctca
    21781 actaatggtt ttatttcgct aattatagca aataatagaa caaaaaaaca gacaaggctg
    21841 tttttggcag gaatttcttt tttaaaagag ttaaaacgtg agaaaatgat ctttattata
    21901 aaagagttct taagcttttc tttagagaaa atttcagtta ctatggagaa cagggcaaag
    21961 aaaaatcaat cattttcttt gtatatcatc ttaccaatat ataggaattg ttagtaacaa
    22021 ttgcctttca aggaggaatc catccatgtt attaggctca cacgtcagca tgagcggaaa
    22081 gaaaatgctg ttaggagcag cagaagaagc agccagttat ggatcttcga cttttatgat
    22141 ctatacaggc gcccctcaaa acactagaag aaaagccatc gaagagatga atattgatgc
    22201 cggaaaagcg tacatggcag aaaaaggtct aacaaatatc gtcgttcatg ccccttatat
    22261 cattaatttg gggaatacga tcaaaccaga aatgtttcct tttgccgtcc aatttctgag
    22321 agaagagatt gttcgtgcgg aagctttagg cgctactcaa attacacttc acccaggtgc
    22381 tcatgtaggg gcaggaacag aagccggaat tgctagaatt attgaaggct tgaatgaagt
    22441 tttgacaaaa gaacagacgg cacaaatcgc tttggagaca atggcaggta aaggtacgga
    22501 aatcggtcga acatttgagg aattagcgca aatcatcgat ggagtaaaat tgaatgaaaa
    22561 attatccgtt acttttgaca cctgtcatac gaatgatgcc ggttataata ttaaagaaga
    22621 cttttcaggt gtaatggaag agtttgataa gatcatcggg ttagatcggc ttaaagtact
    22681 ccatatcaat gattctaaaa atccgcaagg ttcgcataaa gaccggcacg ccaatattgg
    22741 ttttggaaca atcggattcg acacgctgaa taagatcgtc catgatccaa tgtttgacaa
    22801 tatttcgaaa atcttggaaa ctccctatgt aggcaaagat aaaaagaaag cttacgcacc
    22861 atatggaaaa gaaatcgcca tgttcaaagc gcaaacattc gatccagaag tgtttcctga
    22921 gttattagca gaagaagtga tactctaaga ttttctatct gacagcagca aaaaaggacc
    22981 aggcacattg ccttgtcctt ttttgtttaa gaaacaaagg agtacttttt gcagtctttt
    23041 tcatcatgca tcttctcccc cctcttttta aatttagaca aacaaggtat actggtagaa
    23101 aagtaaaaaa acgaaaagtt tcacaagcaa gtggcaaaac gtgattggaa ggacgaaaag
    23161 atgctgaaca ctttaaaacc cttgatcaac caactaaaaa agaaacatac atactttatt
    23221 cttggcatag ccctattatt tacaattatt cgtttgtatt tatatagtaa agcaatctat
    23281 ggaacagaca tgtcggcaac ctatgatgac cagctgctga ttcgctatgc tcaaaatatt
    23341 ttggacggta aatggctagg ggagtatacg actacaacac tttccaaagg aatctcctac
    23401 agcttatttt tagtacttgc acataaactg catctttctt atgcagtttt gttcggcatg
    23461 ttcagtattt ttgccagtat attggttgca ctcgcgttta aaccgattgt gaagaacaag
    23521 tatcttcttt taagtatcta tttttatttt ttgttttctc cgattagttt tacacatgaa
    23581 tattccactc gaacatatcg taatgccctc gtgattccgg ctgttgagat cattatcgct
    23641 tgtttattag ctatttatta ccgcaaatac ggttctagca gaaaattgct gccatggttt
    23701 ttagggcttt ctgtcgcttt tcctttcttt tggttcattc gcgaagattc tatctggctt
    23761 cttcctttta ctgtagtagc tttgggtatc agtttcgtcc agatcttgct agggcaagac
    23821 ttttctttca aagaagtaaa gaagttaaaa aaacgactct ttcttctctc gaaacgggaa
    23881 tggctgaaac tttcattgtt tttacttcct atagttggct tttccatcgt ctatcaatgg
    23941 atcgaatata aaaatgagac aacatacggt attgcaacca tcaatgaccg ttccagtgga
    24001 gaatttggac gtttgatgaa acaactgatc cgaatagatg atgaaacgaa cttgaataaa
    24061 gaaaacagtg agatatgggt ctcacatgct gcactaaata aagcattagc cgcatctcct
    24121 acattccata ctgtttctac ccgtattgac gaattatata cgactcacgc gtggactcaa
    24181 ggtggaaaag taaaagaatt acccggagat atcatctttt gggcattgcg agatgtggta
    24241 agcgaatctg gttattacca aaacaatgca aaagaaacca atgatttttg gaaaaaagtc
    24301 aaccaagaat tagaagaagc ctatcacaag ggaacaatca aaaagaaaaa agagttctat
    24361 ctgatgggat caggagatgg aaagacgatg agtgatctgc caatcgtatt cgatttcctt
    24421 caatcaggat acgcttatgc atggcgatat aaagatttcc atcaaggagg aaattatagt
    24481 ttcggaacgc aagaacaagt caaacaggct caagaattat taaaccttcc gctaatggag
    24541 aattggatcg atagtaatga accgagaaca cctaatttcc aattaacaaa atcagcaaaa
    24601 gtcgcgaatg tcatcataaa aatttaccaa gttctggcta ttcccgtgct gattgcttca
    24661 atagcaggga tattacttat gatactagga accgtatttg caaaagctga tcgtgcctat
    24721 tatagttcct ctttgattgt ggtcaccgga ttaatactga cacaattggt ttttcttttc
    24781 ggtgtctcat ggttttgttc ttatgcgcca gaaaaaaagg actatttttt aagtgtctac
    24841 actggtgcag gcgtgccatt aacgcaattc atcgtagtaa caagcatgct agttttcagt
    24901 aaattaaatc tgaaaaaagc tttatcttct aaataaaaag acccttggta gctagatttt
    24961 taacctaact atcaagggtc tttgtgtgga aaaatcagtt tttattcgat ttcttctacc
    25021 gtttcctgca aaagctgttc atattttttg tttcctttat ataaatcacc aatcgtccat
    25081 gccaacagga gaaggacaag aacaatgatt acataagcga tgtgatcagc caatgctagt
    25141 tgagcggaag tggcttgctc gccgaagaaa ctttcgatct gtcctggtaa tcctcgtaag
    25201 ttcaagtaag ttagactaat cacagagaac cagccaagaa gttttacgat gaatgaattt
    25261 ttaaatcggc tacccatctc cgcttggctg ttggtcatca tcagtaaagg aatcatcgaa
    25321 aacggcaacg caaaagccaa gaacacctgg gattcattca ttaagttatt caaagcggca
    25381 tgttcttcga tcgttccttt tgtacttgta aacaaaacac aaatcaatac aggaatcaca
    25441 gaaagcaatc gtgtgaccag tcttcttagc caaatcggga tacgcatatg gatgaatcct
    25501 tccatgatga cttgaccggt caacgtacca gtaatagtag agttctggcc agaagcaaga
    25561 agtgctacag caaataaagt ggacaagata ccagattttg ctacagcaat caaaatacca
    25621 ttgctcatag ctgatggatc agataaagct tcatacagac caaaaaagga aggatcttgg
    25681 acagaaccgg ttttgaagac agcgacaccc atgatcaata gcagtgcatt gactagaaaa
    25741 gccattgaca actggatatt agaatcccaa gtagaaaaac gtacagcttg tgctacatct
    25801 tcttcgtttt ggtgatcgat cttccgagtt tgtgaaactg ctgaatgaag atataagtta
    25861 tgcggcatga ctgttgcacc aataatccct aaagctccag tcagcggagt ttcgccgccg
    25921 atgaccggtg agtctgagaa tgtatgactg ttagggataa agccagcaaa taaactgtgc
    25981 caatctgggt tagacaagcc aacttgatag acaaaaacga ataaaatgac gaaaattaag
    26041 cagacaacca gtgcttcgat cttacgaaac ccgacttttg tcagtagtaa gagaacgaaa
    26101 acatctaata cagtaataaa gacggcaatc accaatggaa tatcaaaaag taagtagagg
    26161 gcgattgctg caccaatgac ttctgcaata tctgttgcca taatggctaa ttcagtcaag
    26221 atccataaaa tgacacctaa tgtcttactt gtgcgtgctc ggattgcctg tgccaaatcc
    26281 atttggctca cgattcctaa ttttgctgcc atatactgta aaagcatagc aatcagacta
    26341 gacatcaaaa taactgacat caataaatat tggaaatttt gtcctccggt gatcgaagta
    26401 gaccagttac ccgggtccat atacccaact gctactaacg caccaggtcc agagtaagca
    26461 agaagtgttt taaaaaaact tttccccttt ggtacatcaa ctgttccatt tacttcagct
    26521 aaagataaac catttgtatg ttcaataagt cgatgcttat gaaattgttt attggattga
    26581 ttattcaaga aaaaaccacc tttcctattt atctacgatt acattctaca cctcaaaaag
    26641 aaaaaattaa agaaaaagat tcggtacgcc taattttttt tcatggcgcg tcttgctaga
    26701 tgacgaaaga aattttgttc tcctctaaaa aaaccactat tttttgcatg aaactaaaga
    26761 atacgccttt cttttttcaa taaactttag taaaataagt cattgagagc aattcggaaa
    26821 tagaaaggag agatttatat gttatcaaca ggtattgtcg tacttattgc tattattgct
    26881 ttgctaatcg gcgcagtagg tggctttttc ctagcgcgta aatatatgaa agactattta
    26941 gaaaaaaatc ctcccgttaa tgaggacatg ttgcgatcaa tgatgatgtc aatggggcaa
    27001 aaaccatctg agaagaaaat tcgccagatg atgcagcaaa tgaagaacca agggaaaaaa
    27061 taggttctga cccaacgact ttttacgggc tgattttttc agtccgtttt ttatttcgta
    27121 atttgttaga ctattcagat tattcagcaa aaaagacaag cacagacaat cctaggctct
    27181 tgataaagac aaaggaggag taaaatgtcg atttttagaa aattaggctg gttttttcgt
    27241 caggaaaaga aacattattt aattggggtt ttctcgctat tcgcagtggc cttggtacag
    27301 ttagttcctc caaaagtgat tgggatcatc attgatgaga tcgccgataa aaatttatca
    27361 ataaagatca ttttcgggtg gatcttccta ttgattatcg ctgctttttt acaatatctt
    27421 tttcgttata tctggcggac gaatatttgg ggaagtgcag ctcgattgga gaaagaactt
    27481 cggcagcagt tattcaaaca ttttacagaa atggacaatc tcttttacca aaaatatcgg
    27541 actggggatt tgatggctca cgcaacgaat gatttgaatg cgatccagaa tgtagcagga
    27601 gctggtatct tgacctttgc agattcagtg attacgggcg gaacaacgat cattgcgatg
    27661 attttgttta ttgattggcg cttaacactg attgcgctga ttcctctgcc tttgctggcc
    27721 gtcacttcac gagtgctggg gtcaaaactc catgatgctt ttcgtgattc gcaagaagct
    27781 ttttctagta tcaatgataa gacacaagaa agtatcactg ggatcaaagt cattaaaaca
    27841 tttggacaag aaaaagaaga tctagcggat tttgaagaaa agattgaaga tgcaattatt
    27901 aaaaacaaac gagtcaattt tttagactcc ttatttgatc cattcattac cttgattatc
    27961 ggtctgtctt atgttgcaac aattatttta ggtggaaagt atgtcttgga aggcacgatc
    28021 tcgatcgggc agatggtctc atttattagt tatatcggta tgcttgtttg gccgatgttt
    28081 gcgattggtc gattgttcaa cgtattggaa agaggaaatg cttcttatga tcgcgtcaat
    28141 gaacttttgc atgaaaagac gcatatcgtg gaacaactgg gtgcagtgca gaccccggca
    28201 aaaggcgagc tgaatgtagc tatttcctct tttaattatc cgaaagaaga atcaccagca
    28261 ttagaacaaa tcaagtttgc gatccaagaa ggagaaacat taggtattgt tgggaaaact
    28321 ggtgcgggaa aaacgacgat catcaaatta ctgatgcgtg aatacgatga ttatcaaggg
    28381 aaaatccaat ttggcggacg ttcgatcaaa gaatattcat tgaatgcttt attaggatca
    28441 atcggctatg tgcctcagga ccacttcttg ttttcgatga ccattcgaga taatatccgt
    28501 ttttctaatc caaaactttc agaagaagaa gtagagcatg cggcttcttt agcatttatc
    28561 aacaatgaaa tcaaggaatt accaaaaggt tatgatacct tagttggaga acgtggagtc
    28621 tctttatctg gcggacagaa acaaaggatt tcgattgctc gagcattgat caaaaatcct
    28681 gaattattaa tgttagatga tgcactttct gcagtagatg ccaaaacaga agaagctatc
    28741 ttgcataatt taaaagaaat aagaaaagag aaaacaacta tcattgcagc tcaccgttta
    28801 agtagcgtaa tgcatgcaaa agaaatcatt gttgtcgatc aagggaaaat cattgaacga
    28861 ggaacccatc atgagctgct tgcactaggc ggctggtatg aacaaatgtg ggagaaacag
    28921 caattagaag cgaagataga aggaggcgag gcctgatgga tgaaaattat caatcggaat
    28981 ggacaaaatc gattccactt aaagaacaga aaaagatcat cacacgactg atgaagttcg
    29041 ccaaaccttt tagaagaacg ttcatcgttg ctatcttatt tgcgtttgct ctgtctgtga
    29101 tcaatgtcct attgccaagg atcatccaaa cttttatgga tgatcatctg gctaaacagt
    29161 cggctacgac acaagttatt ttgttttttg ctggtatgta cttatttgga gtcatagtaa
    29221 aaagtatcat ttggtttttc caatggtatt tgtattccat ggcttcattg aagacctatc
    29281 agtatattag ggtaaaatta tttgaaaagc tgcatacact aggtatgcgt tattttgatc
    29341 agacaccggc aggttcaacc gtttctcgag tgacgagtga cacagaaacg ctatttgaat
    29401 tttggtacgt ctttttgatg gtattgactg ggatctttgc agtcgtttct tcattcattg
    29461 ccatgtttca aatcaatgga gaaattgcct tgtggacttt ggtgttcttg ccaattttag
    29521 gaatcgtcat ctggtattac cagaaattta gttctcgtat ttaccggaat atgcgagaaa
    29581 aattaagtca gctgaatacg aaattgaatg aatcgatttc cggcatgcgt attatccagc
    29641 agtttcgcca agaagctcgt ttagctaaag aatttgaaca agtgaacaat gagtatttag
    29701 acacgcgtta tgcgatgatg aaaacgaatt cgattctatt aagtccgatc atcaattttc
    29761 tatatgcact ggcgattgcg ttggtgttga ctttgtttgg gatcgatgcg ttgcattctc
    29821 ccatagaagt tggactgatc tatgcattta cgacctatgt ccagggattt tttaatccaa
    29881 tgtctcaaat gatggacttt ttgagcatct tcacagatgg gatggttgct ggtagtcgta
    29941 tcttgaagat tatggataca gaagaatatg caccacaaca aaaccctgga gcagatcaaa
    30001 tgattacttc aggtaagatt gagtttcgca atgtaagctt ttcttatgat ggagagcaca
    30061 atgtattaaa caatatctct tttgttgcta atccgggaga gaccgttgca ttagtgggac
    30121 acaccggaag tgggaaaagc tcgatcatca atgtgttgat gcggttttac gaattttatg
    30181 aaggtcagat attgattgat gatcatgaca ttcgagaata tccaatggaa gagttacgta
    30241 agaaaatggg gctggtcttg caagatgctt tcttgtttta tggggatatc gcaggaaata
    30301 ttcggatgat gaatccagct atcacagacg aacagatacg ccatgcggct gagtttgttc
    30361 aagcaaacaa attcatcgat gaattaccaa aaggatatca ctcaaaagtg atcgaacatg
    30421 gtgccagcta ttctagtgga caacgacagc tgatcacttt tgcgcgaaca atcgtgactg
    30481 atcctaaaat tctagtattg gatgaagcaa cagcaaatat cgatactgaa acagaaggat
    30541 tgatccaaga aggattggcg aaaatgcgac aaggacggac aacgattgcg attgcccatc
    30601 ggctgtcaac gattcgagat gcagaattga ttttagtttt agacaaaggt catatagtag
    30661 aacacgggaa tcatgaaaca cttctagcgc aaaatggttt gtatgcagat atgtacaaac
    30721 tgcaaagcag tggtatataa aagatgttgt gacagtagca ttttgaccta agcactagag
    30781 tgaaaataaa acatagcttc ccatattttt catctgtgag agttagtgtc gtagttacca
    30841 gatttaaaaa agacgacgcc agctagtcag aagtgcctag tagcccctaa gaaagcgttg
    30901 acaaaatcgt ttgctttcga taatacaaag aaaacgatac aacttggata gtgattgcct
    30961 aatgcaagct aaacctgatg agtctcccat ggtttcatgg acggcttttt gggtttttct
    31021 ttttgttttg gatacagccc tatatatcat ggaaaggagc aaaacatgct gattgagaaa
    31081 gtactgaata acaacgtcgt aataaccagg gatgaaagaa atcaggaaat gatcgtgatg
    31141 ggaaaaggtt tggcattcaa aaagaaagtg ggtgacccga tttttgactc atgcatcgac
    31201 aaaaaatttc agttgacaaa tgacggactt tcacaacagt tccaagaatt ggcacaagcg
    31261 attcctcttg agtacttaga aatttcttgt gaaatcattg aatatacaaa agaggatcta
    31321 caagtccatt tgaatgattc tgtgtatatt gcattgacgg atcatttgta tacagctatc
    31381 gaacgtcaaa aaatggggat ctttgtgcca aatgtattgc tgtatgatat caaacaactg
    31441 tttcctaaag agtatgccat tgggaaaaaa acagtgaaga aaatctcgga taaataccac
    31501 atcaagttat cagaagacaa agccggattt atcgcattgc atttagttaa tgcacaaggc
    31561 attcaaagcc agcaagacaa tacctacctg tttaccacaa caatacagga tattttaaat
    31621 atcgtccgct gttactataa gattactttt gatgaagatt cagtccattt ttttcgattt
    31681 gtcacacacc tacgtttttt tctgacacgt gttctagatg gagcgaaatc agaagatgga
    31741 gaagtttctg aggaattgtt ccaagttatt caaaaaaaat ataaggatac gtttggttgc
    31801 gttgagaaaa tagcagactt tttaaccggg gctttcgact accagatgtc cacggatgaa
    31861 aaaatgtatt taacgatcca tactgcgcgt ttagtgcatg agaatcgttg taaataaata
    31921 aaaaggagga caaattaaca cgaacgtatg aaataagggt agtgacattc agttggctaa
    31981 accttccact aattaattgg agggaacaga aatgggaaaa taccaagaat tagcgagcaa
    32041 aattgtagaa aatgtcggcg ggaaggaaaa tatcaatggt ttgacacatt gtatcacaag
    32101 gcttcgtttc aaattaaaaa acgaagaaaa agcaaatgat gagatcttga aaaatatgga
    32161 cggtattgtg acggtaatgc gagcgggagg acagtaccaa gttgtcatcg ggaatcatgt
    32221 gcgagtcgtg tttgaagagg ttataaaagc aggaaacctt acttttgatg aggctgtttc
    32281 aacagaaaaa atgagaccgt ttgatatgct tattgatgga atatcgggat gtttccagcc
    32341 attccttgct atcctggctg ctggtgggat gattcgtgga ctgacagcat tacttgtctt
    32401 cttaggcgcg tttgatcgcg gttctggaac atttgttatg ttcgacaata tcggtgattc
    32461 tgtattccaa tttatgcctg ttattatcgg tttaacagtt gcccgtaaat ttaaagtaaa
    32521 tgaattcgta gggatgttgc ttggcgcagc attaatgaat cctaacttgt cgctggaagt
    32581 tttgagtggt gcagcagaag caccactgac gaccatattt tctggtacta tttttgaagc
    32641 acctatttat caaacagtat ttggcattcc ctggattgcg cgtaactacg cttcttctgt
    32701 cattcccatt atctttattg tgttgttagc tagccaaatt cagaagccaa ttaaaaagtt
    32761 agtacctgag atgatcgcga atttcttcgt tccattcttc accgttctta ttacaatgcc
    32821 cttaggtttt ttactcgttg gaccagcatt cacattcgca actgatattt taatggctgg
    32881 atttgaaaca cttttagcac tttcgccagt taattatgga gcaatcgtag gcttcttctg
    32941 gcaaattctg gtgatgtttg gtctccattg ggcaatcgta ccaatgggat tgatgcaatt
    33001 ttctgtgaat ggctggcaaa atatcatgac acctgttgca gtagtgtctt ttggacaaac
    33061 tgcagcactt actgcactct actttaagct tagaaaccca aaagacaaag caatcgcaat
    33121 gccagccatt gtttctggta ttgtggggat tacagagcca gctatttatg ggtttacatt
    33181 gccacgtaaa aaaatattta tttttacctg tgtcggtggt gcgttagggg gcgcgtatag
    33241 tgggttaatg aatttaactt cttggaatca aggtggacta ggcatcttta cgattcccaa
    33301 ctatattaga ccagatggtg atttaacaga tgtgattaat gtattaattg ggatcgccat
    33361 tgcgatggtg gtatcctttg cgctgacttt tttcttttgg aaggatgaag caggtgaaac
    33421 agatgatata cagaaaagat cgggtaaaga aattgtaaaa acaccgatac aaggacaaat
    33481 cgctccacta aatgcagcga aggatgcagc ttttgctcaa ggaacattag gtcgagggat
    33541 cctgatctac cctgaaaaag gagaagtacg tgcccctttt gacggaacag ttatgaccct
    33601 gttcccgacg aaacatgcaa tcggaatggt ttctgaaaca gggctggaat tgctgattca
    33661 tgtcggattg gatactgtgc agttggaagg gaaatatttt gaaagcttag tgcagcaagg
    33721 agaaagagtg aaacaaggcg acctgttgct acgcttcgac aaaaagaaaa tcgaaaagga
    33781 aggatacagt ttagaaacac ctgtgatcgt caccaattat acggattatt tggatatttt
    33841 ggaaaaccaa ggggagacgg tcgggccaga cgatgcactt atcaccgcac tgacctgaac
    33901 ggttaggtga agaatggact aggcttaact attcttttta ttccacttct ttattttcaa
    33961 aattgaaagg ctctttcatg atggctgagc tgatagggcg tttatcgaat ttttgaccga
    34021 cagaaattag atggactaaa ttctgctgat aattttctgc aaaaacacaa ctatataaca
    34081 cgtctagaag ataacaaatt gatgtattga tcgtaaaatt accaattttt gaatacagtc
    34141 gctcgcgtgt cgtaagtcgc aaagcggctg tactcattgc agatagcgtt gaatcaccga
    34201 tactggtcaa agctaaaatt ggaacatcat tttgtttcaa tatttctgcg gtacgaagga
    34261 tcacattgtt ttcacctgta taagaaatca gaatcccgca catatcgctc gtgcaattgt
    34321 acgcttcata gaatgattca ccaaaagtgg tgacaattgt gacatccatt ttgatgcgct
    34381 tcattttcag catgaaatct tgagaaatca aagtattcga gttactggcg aagatcacga
    34441 ttttttttgc ctggagcagt aaatacttag ctttttgcag ttggtcatga tgaatgagag
    34501 aaagtgtatc ttgaatcgtc atctgttcta aagaagccat tttatttgcg atcgtcataa
    34561 taccgtctgt ggtggaaaaa ggaagattcg catctacgtc ttgaaaattc ccttcaagat
    34621 aggctgtttc agctaaaaaa gcattacgaa aactgaccca gccatcaaac cccatttttt
    34681 ttgctacacg gatgagtgtg gacgggtgga cataacatcg ctcagcgatc tcttggatgg
    34741 tcatttcgcc aagtgctgga gaatcgctta agagaaactg gatcacttca ttttctgaag
    34801 gagaaaagga gatttctttg attttttcac gtaataacat gtagatacct tcttcttatt
    34861 tttttacgta aattataact tttttgaaaa tgatttgtaa acggatttat actatataac
    34921 ttaaaataga cattttttga caagatattt acaaaaatcc actagaaaac agtaactttt
    34981 gtaaatgtta ctggaaagaa acggatttct attgtttgtt ttgtttacaa aaaagataat
    35041 taaagtgtaa aaaagtaaag gagtgagaac atggcaaaag gaatcaaaat cgctacgatt
    35101 ggtggaggca gcagttacac ccccgagttg atggaaggat ttatcaaaag atatgaggaa
    35161 ttaccgatac gagaaatctg gctcgtagat gtagaagaag gaaaagaaaa gcttgatatc
    35221 gttagtcaga tgtctcagcg tatgtgggat gcttctccgt atgaagtcaa gatctatgca
    35281 actctggatc gggaagaagc attgaaagat gcggattttg ttacgactca gtttcgtgtc
    35341 ggtcaattag atgcacgaat caaagacgag cggatcccta gttattacgg gatgatcgga
    35401 caagaaacaa atggtgctgg cgggatattc aaagcttttc gtaccgtgcc agtggtcttg
    35461 gcaatcgttg aagacatgaa gcgtttatgt ccaaatgctt ggctgatcaa tttcgcgaac
    35521 ccaagtggga tggtgacaga agcagttatc agatatggta aatgggataa agtgattgga
    35581 ttatgcaatg tgccagtaat ggcgatgatg acagaaccag caatgcttgg caagaaaaaa
    35641 gaagagctga tctacaagtt tgccggtcta aatcatttcc attggcacaa agtagcagat
    35701 aataaaggaa atgaccgcac ggcagaattg attgatcgtt tatacgatga agacaatgga
    35761 ttgccgaaaa atatctttga tatcccgttt ttcaaagaac aattaaaaca aatgaacatg
    35821 atcccttgtg gctaccaccg ctattactat cgtgaagaag aaatgctgga acatgcttta
    35881 gaagaatatc aaacgattgg tacaagagcg cagcaagtga aagaaacaga agcagagctg
    35941 tttgaattat acaaagatcc agaattagac cataaacctg aacaattgca aaaacgaggt
    36001 ggcgcttatt attcagacgc tgcctgtgaa acgattactt caatctatgg aaataaagaa
    36061 acacagatcg ttgtatctac aaagaatgat ggagctgttc ctgacctgtc ggcagattgt
    36121 gttgtagaag tcactgccta tgttggcgca caaggagcga gaaatgtagc gtttggttct
    36181 cttcctgctg ctgaaagagg ctggttgcag gtaatgaaga atatggaatt gctgacgatc
    36241 gaagcagctg tgactggtga ttatgggaca gccttacagg cgtttacgat caatccactt
    36301 atacgatcag gaaagacagc aaaacggatc atggatgagt tgtttattgc acaccagcag
    36361 tatttaccgc aattcaagga aacaatcggc cgattaaaag aagaaggaat cgaagttcaa
    36421 gatgaactgg caagagaatt atcaagtaat acacatataa tggaggaagt ataatgggat
    36481 tcagaaaaga ttttttatgg ggcggtgcta cagcagccaa tcaatgtgag ggcggttatg
    36541 atgaaggtgg acgcggacta gcaaacgtag atgttgtgcc aatcggaaaa gaccgttttc
    36601 ctgttatcac cggaaagaaa aaaatgtttg aatttgatga ggaccatttt tatccagcaa
    36661 aaattgcaat cgatatgtat catcgttata aagaagatat tgctttgttt gcagaaatgg
    36721 ggttcaagac ttatcgaatg tccatcgcct ggagtcgtat ttttccaatg ggggatgaga
    36781 aagagccgaa tgaagctggc ttgaaatttt atgaggatgt ctttaaagaa tgccaaaagc
    36841 acggaattga gccacttgtg acgattacgc attttgattg tccaatgcat ttgatcaaag
    36901 aatatggtgc gtggcgttcc agagaactcg ttggttttta tgaaaatctg tgtcgagtca
    36961 tcttcaatcg ctataaagga cttgtcaaat attggctgac attcaatgag atcaatatga
    37021 tccttcatgc accattcatg ggcgcagggc tgtattttga aaaaggagaa aatgaagaac
    37081 aaatcaaata tcaagcggca catcatgagt tggttgcaag tgccatcgca acgaagattg
    37141 ctcatgaagt agatccggag aacaaagtag gctgtatgct ggcagcagga gcatattatc
    37201 catacacttg caatcctgaa gatgtttggg attctagaaa atcagatcga gaaaattatt
    37261 tcttcattga tgttcagtca cgaggagaat acccagctta tgcattgaaa gaaatggaac
    37321 gaaatggcat tcagatcgaa atggaaccag gggatgccgc attgctgaaa gaacatactg
    37381 ttgattttat ctccttttct tattattctt cccgagtttc gactaccgac aacgaactct
    37441 tggaacagac tgcaggaaat atctttgctt ctgtcaaaaa tccatatctg caagcaagtg
    37501 aatgggggtg gcaaattgat ccattaggct tgagaataac gatgaatgat atttatgatc
    37561 gttatcaaaa accattattt attgtagaaa acggcttagg tgcagtcgat acgccagatg
    37621 aaaatggtta tgtggaagat gattaccgaa tcgattacct ggcagcgcat atccaggcga
    37681 tgaaggatgc agtagaacta gacggagtcg atctattagg ctatacgact tggggatgta
    37741 ttgatttagt atcagctggt accggtgaga tgaagaaaag gtacggattc atttatgtcg
    37801 atcgtgataa ccaaggaaat ggcacattag cccgttcaaa gaaaaaatca ttcaactggt
    37861 ataaaaaagt aattgattca aatggagaaa atctttcgaa cgattgatca atgatttata
    37921 aaagtctatt gtttttcagc ggatttttcg agtataataa agctattcga gaaacgcaag
    37981 cagaacaata gacttttttt cgcattggct gtaaagtatg cttacttgat taagtaaagg
    38041 agaatctaca tatgtatgat gtaatcgtta ttggcgcagg tcctgctggg atgactgctg
    38101 ctttatatgc ttcacgttca aacttatccg tattgatgat cgaacaaggt gcccctggcg
    38161 gccaaatgaa caatacggca gaaatcgaaa attatcctgg attcgattcg atcatgggcc
    38221 ccgatctagc ttataagatg tatgaaagtg tctcaagatt tgggacagaa aatgcttatg
    38281 gaatcgttca agatatcaag gatcacggca gccataaaga agtcatctgt gaagataaaa
    38341 gttacgaagg aaaaacagtc attatcgcaa caggctgtat ccaccgtaaa ttaggcgtac
    38401 ctggcgagga agaatttgct ggacgaggcg tttcttactg tgcagtctgc gatggtgcgt
    38461 ttttccgtaa caaacgtcta gtagtcatcg ggggtgggga ctcagcagta gaagaagcca
    38521 tctatttgac acaatttgct tctgaagtag tgatcgtcca ccgtagagat gaattacgtg
    38581 cacaaaagat catccaagac cgtgcatttg caaatgaaaa aatttccttt atgtgggata
    38641 cagtcgttga cgaaatcgtt ggaaacgaaa tggtagtgac aggtgtgaaa gcacgtaatg
    38701 tcaaaaccgg caatgaattt gatttagcag cagacggagt attcatctat gttggactgg
    38761 atccattaac tgcacctttt agagaagcag gtttgacgaa cgaagctggc tggattccaa
    38821 cagacaacga aatgaaaacg aatatgccag gcgtttttgc catcggagat gttcgtgaaa
    38881 aagatttgcg acaaatcact acagctgttg gtgacggcgg tattgctgga caacaagtgt
    38941 ataaatactt ggagtcttta gaagaaacaa cagcataagt ttaaaaagag tgaaagaacg
    39001 gttttaattg ttcttttact cttttttttt cgcgtgaaat ccactgaatc cgatttatgt
    39061 gaatacttgc aatcatgctt gataaaagaa tcctttcttg atttaagcgt tttttggtcc
    39121 tcatactttc atatctaata agtgaatgct atacttatta agaaccatat ttcagaaaga
    39181 ggtgttattt tcatgtcttg ggaacaagtg tatgaacaat gggtacatga agaaaattta
    39241 gaagaaaact taaaaaaaca attaaatgat ctgggtgaag atcctgaaaa acttgaagat
    39301 gctttttatg caccgttgga attcggtact gcaggcatgc ggggaatctt aggacctggg
    39361 atcaatcgaa tgaacatcta tacggtaaga caagcaacag aaggactagc acgtttcatg
    39421 gatacacaag gtgaagaaac aaaacgccga ggtgtcgcta tcgcttatga ctcacgccat
    39481 cagtcaccag aatttgcaat ggaagcagcc aaaacactgg cacatcacaa tatcccgtct
    39541 tatgtattcg aaagtctgcg tccaacacca gagctttctt ttgcagttcg tcatttgaag
    39601 acgtttgcgg gaatcatggt aaccgcatct cacaacccag cggcttacaa tggatataaa
    39661 gtctacggag aagatggcgg acaaatgcct cctgcagacg cagatgcatt gacgaaatat
    39721 gtccgtgaag tcagcaatcc gctaaaagtc gaagtattat ctgacgaaga agctaaacat
    39781 agcgggttga tcacgatcat cggagaagaa gtggacgctg cttatctaga agaaatcaaa
    39841 gcagtgacga ttgatcgtga attggttgaa acaatgggga aagatttgaa acttgtgtac
    39901 acgccacttc atggaacagg gaaaatgttg ggcgaacgcg cgttgaaaca agctggattc
    39961 gaacaattcg tactagttcc cgaacaagct gtggcagatc cagatttcac tacggtcaaa
    40021 tcgccaaatc cagaagaaca ttcagctttt gaatatgcta tacgacttgg agaaaaagaa
    40081 ggagctgact tgctgattgc aacagatcct gatgcagacc gtttaggcgc agcggttcgt
    40141 ttgccagatg gttcttatga agtattgact gggaaccaaa tcggagcatt gtttgctcaa
    40201 tatattttgg aagcacatca atcaagaggc actttaccag aaaacgcagc ggtattgaaa
    40261 tcaatcgttt ccagcgaatt gcctacagca attgcggaac actacggtgc taccatgttc
    40321 aatgtgttga cagggtttaa attcattgct gaaaaaatcc aacaattcga agaaaaccat
    40381 tcacatactt ttatgtttgg attcgaagaa agttatggtt atttagttaa accttttgtt
    40441 cgcgataaag acgcgatcca agcattgctt ttattagcag aagtagcagc ttactataaa
    40501 aaacaaggca aaacgttgta tgacggcttg caaacgattt ttgaaaccta tggctatttc
    40561 gcagaaaaaa cgatttctgt gacaatgagc ggacaagaag gttctgcgaa aatctctgct
    40621 ttgatggaaa aattccgtaa agaagcaccg acagaatttg ccggagcaaa agttattcaa
    40681 acagaagact ttaaagaatt gacgagaaca gaccgtgaag gaaacgtaga aaaactcaca
    40741 acaccgccat ccgacgtatt gaaatataca ttggaagaaa atggctggat tgctatccgc
    40801 ccttcaggaa ctgagccgaa aatcaagttt tatattggtg taaaaggaag ctctacagaa
    40861 gacgcagcca aaaaagtagc ctcttatgaa gcgattatca aaaagatgac agaagaataa
    40921 aaaacttgag actgatggaa aaagtggtaa actttagaag tcagtctttt ttcaagttgg
    40981 aggtgaatgg attgccagac acgcaaaaat caaaagtaga gaaagtcagt caattattca
    41041 aaatgttgag tgatcccact cgtcttaaaa ttctgctata tctgaaagac ggggaacaaa
    41101 atgtgacagc aatcacccaa gcagtggaaa tggagcagtc tgctgtatcg catcaactac
    41161 gtttattaag agaaaatcat gtcgtcaagt ctcatcgcga gggaaaagcg attttgtata
    41221 gtcttgatga ttctcatgta ctggatattt tgaaccagac actcaaacat gtggaacatc
    41281 aataacgata ggtgcaaata gataaacact ggagtgtgac aacgaaattt cttcgttgtc
    41341 acactccagt gttttttaag aaaaagacaa aaatgatcaa tcgctttttt ctgttgtttc
    41401 agttccataa taactatgat cttctaggtc taaagcattc aaaataagcg aagccgtttc
    41461 ttcaatagat aaagatgcta cattgatcac tacacatcct agtttttcat aaagatcatt
    41521 cgcaaaatcg agttcagctc taattttttc gatatcggaa taagcagtat cagggtttaa
    41581 tccgtaagag cgcatccgtt ctttacggat attatttaaa atatctgggt tattcgttag
    41641 tcccacgatt tttttaggat cgatctccca aagctgtttg ggaatatgtg cttgtgggat
    41701 caaaggtaaa ttggcaactt ttaaattttt gttagctaaa aacaagctca aaggcgtttt
    41761 ggaagttcgg gatacgccta gcaaaacgac atctgcttct aaaaaaccac gaggatcttt
    41821 cccatcatcg tattttacag caaattccat tgctttgatc cgtttgaaat agttctcatt
    41881 caataaatgg agggcaccag gttgccgaat tggcttgata ccagttaaac gttcaatttc
    41941 tgatatcggt ggcgtcatca catcaaaact aaataattga tgttcttcac aaaaagaacg
    42001 tgttatctcg atcagttctt gattgattaa tgtatgcagg acaagtgctt tttcttctaa
    42061 tgcatcttgc aatgcctgcc ttaatgtttt ttcatctgtc acgaacgttc tgcggaatag
    42121 gttgaactca acggtaggat actgagccat agtagcttgc gctagttttg tcgcagtttc
    42181 tccagcagag tcggagatga caaaaaaagt aacgatttct gtagaatcgg aagtcatgga
    42241 taaaacctca cttgcatttt ttttatgttt attataccat actctagaat gcgtacttcg
    42301 taatcatttt gatttggagg aataagtcat gaaaaaacag acattgatcg aacaatcatt
    42361 agaaacattg aaaaataacg gttttaaata tactaaaaaa agagaagcat tgttaactta
    42421 tttagtgaag cgtaaccgct acgtatctgc taaagaagtt tttgactata tgaatcagga
    42481 attcaaaggg gtaagttatg atacgattta ccggaatctc catgattttg cagagatcga
    42541 tttactggaa gaaaccgatt taaatggaga aatgaagttt cgttttcatt gctgtcaggg
    42601 ggaaatcggc catcaccatc attttatctg tacagtgtgc ggaacaacga aagaaatcca
    42661 tatgtgtccg atgaattatt tcgaagaaca gctaggtgga tgcacgatcg aagggcatag
    42721 attcgagatt ttcggaagat gtgaaaattg tcaataagga tttaaataaa ataacatttg
    42781 ataatttaaa aaaaaagcaa gatttccttg acggtcaaaa cagcattaga tataatattt
    42841 acaggacagt cttgtttttt gagatatatt tcaataacaa ttacggttac tttttaagct
    42901 cggagggagg gaattaacat gtcaaaaaca gtcgttcgca aaaacgaatc acttgacgat
    42961 gctcttcgtc gcttcaaacg ttccgtgtca aaagcgggta ctttacaaga atctcgtaaa
    43021 cgtgaattct acgaaaaacc aagtgtaaga cgcaagaaaa aatctgaagc agctagaaaa
    43081 cgcaaaaaat tctagttctg tgatgaattg gagttggtag tgtgtcacta ctaagtagat
    43141 taaacgatga catgaaagca gcgatgaaag cgaaagataa ggaatcttta caagtcatcc
    43201 gaatgatcaa gtcatctata caaaacgagc agattaaaga aggtcacgac ttgacagaag
    43261 aagaagaact aacggtgttg tctcgtgaaa tgaaacagcg acgtgattct ttgcatgagt
    43321 ttgaagaagc aggacgtgac gatttagctg aaaaagtaaa aagtgaaatt gtaatagtcg
    43381 aaaaatatat gccggaacaa ctttccgacg aagaaattcg acaacttgtt caagaagcaa
    43441 tcactcaaac tggtgcttca tcaatgaaag aatttggcaa agttatgggt gcaattatgc
    43501 ctaaagtcaa aggaaaagca gatggaaacc aagtgaatgc gattgtgaaa gaactattac
    43561 aatcttaatt ttatcattta aactgcggac agtgattatc cgcagttttt tgtgttcgta
    43621 aaaaaagaac taaaaaacag ctagaagaaa gaatcttatt ctttcttcta gctgtttttt
    43681 tcctgtttaa tatctcttat gttaaattgt gtttgatttg gttattcttc tggtaactca
    43741 cttgcttctt gtttatatcc tgatacgcga tatacataat aaaagagcaa gctgccagcg
    43801 taaccaagca acgttgggac gacccagcca agacctaatg cagcaaaagg aacataatga
    43861 tgataaaatc ctagtaagct tgctacgaca gtttgctgac tcactaatgc aggcgaattt
    43921 gccaacatat ccaatacggc tggaacggca gaaaagaaca tcgttacttg atagacaaat
    43981 ggactctttt ggaagaattt tgctgttaag gaaagtaaga ttaacgcaag tgacaatgga
    44041 tacaaaagca tcaatactgg taaagaccat tggatgatat tatccaatcc ggcattcgca
    44101 acgacaaaag agacaaaagt cgttaaccgc agccatgtca tataactgac tttagggaac
    44161 agtttatgga aatcttgtgc aaaagaaaca acgagtccca tagcagtagt gaagacacct
    44221 aatgtgacca ttacccctaa gaagctagca ccgaagttac ctaaataaaa attagtgatc
    44281 tgagaaagtg cagttccgcc attttctgat aaagacatct tattcaaact catcgcaccg
    44341 agaaggacca gaccaaaata aatcatgact tctaacgcaa cgctcaggct accagctttt
    44401 gctgttaatt ctgtgacttt tttatcttta aaaccaagat cacgaactgc atggacaaaa
    44461 gtgacactta aagcaagtaa agctactgca tcaaccgtgt tgtatccttc taaaacgcca
    44521 tttgtcaaag cgttcgtctg ataagaatct gcagcagatt ggtttagatt ccccatgggt
    44581 tggaataaag aaacgacaaa aatgatagct aataatgcaa gaaacaagga gtttaaatac
    44641 tttccgacat atttgaccaa acgtgttgga tgtacagtaa ggaaataagc aagtaaaaag
    44701 aaaagagcag agaataaaaa catacctaat gaatcatatt tttcaggcaa aaagggttta
    44761 gcagccattt caaaagcagt tgctgctgtc cgcggtgtac caaagaatgg tccgatcgtt
    44821 aaatgaacaa ggatcaagaa caaggcagca taccattttc cgacaggttt agctaagtca
    44881 tacagaccat cactttttgt cactactaca gctaagatag ctaataatgg gaaaagagcg
    44941 cctgagatgg caaatcctac accagcgctg atccagtttg atccagccat ttgacctaag
    45001 tgtacaggaa agatcagatt acctgacccg aagaacatcc cgaagataag tgaactgacc
    45061 atcaataatt gcttccatga ataagttttt gtttcttcca taaatttttc ctccaataat
    45121 tatcattttg agtaacaaaa taaacgttgc agaaactaga aataccacta atatcagatt
    45181 ccatgaaaac caccacctta aaatataaaa aaagcccttt tccacttggg aaaagggctc
    45241 tagattctag aacggtacca ccttttttcg cttaaaaaag cttcttcatt cacggacgct
    45301 tttcgataaa gttatccgct agcctgataa tggaggcagc cacaatgatc tacgttttcg
    45361 acattgactc ggaaatgatg ttcgtctatt cgatttattg tcatttctca cttacatgac
    45421 tcactgggaa taaatcactg aatagcctac tgttttcctc gacgctttgc tgtatattta
    45481 tttgttgacg ttataataca cctgtttttt ttgaaatgca agaatatttc aaatattttg
    45541 ttttcttttt ttgaaacaag aaaaataccc agagaatact tgctaagtta gacggaatac
    45601 ttgtcctcta tcttatgcat agcttacatg atcagctttt tttattcaaa cgagaccttt
    45661 agagaatgga agcggctagt tttttaacgt ttcttggtac ttatggttaa gcaactcttt
    45721 tagaaccttt tcttatttgc tatatagttt cttctgagta tggtaaaata ggaaagaatt
    45781 aatcgaaaaa aaggggatgt ctatttttga cggaagagtc tagttcttta gagattagat
    45841 tgacggctgc tgatgatgtc agcatgcttt taggtgcaca cgacaagcat ataaaactga
    45901 ttgaggaaac aacggaaaca accatccata cacgtggaga aatcattcag atcattggtg
    45961 agcaatccca gatttccttg gctgcctcag tcattcggac attacaggaa ttgatcaaac
    46021 gaggaatcca cgtaagtacg cccgatgttg tgacggcatt gaaaatgggg caaaaaggta
    46081 cattagatta ttttgttgag atgtatgagg aagagatcgt caaagaccgt aatggaaaac
    46141 ctatacgggt aaaaaacagc ggccaaaaga aatatgtcga atcggtagcc aaacatgata
    46201 tcgtatttgg cgtaggacca gccgggacag gaaaaacttt tcttgcagta gtattagcaa
    46261 tcgctgcctt gaaaaaaggt gaagtgcaaa aaatcatttt gacgcggcct gctgtggaag
    46321 caggtgaaaa tctaggcttt cttcccgggg atctaaaaga aaaagtggat ccttatctgc
    46381 ggcctgttta tgatgcttta taccaaattt ttggattgga tcatacgaac cgattgatgg
    46441 aacgaggcgt aatcgaaatc gcacctttag cttacatgcg ggggcgaaca ttggatgatg
    46501 cattcgttat cttggacgaa gcacaaaaca cgacagtcgc tcagatgaaa atgttcttga
    46561 cccgtctcgg ttatcaatca aaaatgattg tcaatgggga tacaagtcag atagacttgc
    46621 ctcgagggac gacaagtggt cttgttcatg cagaacgaac attaaagcaa atcaagaaaa
    46681 tcgattttgt taattttgaa gcaagtgacg ttgttcggca ccctgtagtt gccgaaatca
    46741 tcaaagctta tgaaaaggca gatctccatc aagaataagc tttgcttagg aggataagca
    46801 catgttgaat aaaacactgc agaaactaca agaaaaactt ggaaaggcag cattgccttt
    46861 cctgctgttc ttgtttttta tcattatctg cggcgttaca tttagtagtg tcaaacaaaa
    46921 ggtcaatgat ttcagagaag gccaagtagc agaagaaagt atccgtgcga acaaaacgat
    46981 cgagaacacg gaagaaaccg aacaaaaaag aaaactggca gcagaagcag tcactccaga
    47041 atacacttac caaaaagatc ttgcagatga ccagaacaat cggatcaagc aactatttga
    47101 attgatcgat aagacgaatg atgccatcaa caaatcttat gacgaaaaga ttgataaggc
    47161 aaaggaagat gaaaatatcc caaagcctac tacagaagag cggatcgccg cgctgaagaa
    47221 aaattttgaa aatgtgaatg cagaaaatgt tgtgttttat caaaaactac cgaacaattt
    47281 ttattcgacg atatttgaaa tgactgaaac tgagattcat actgtgaggg atgagagtct
    47341 gaagctcatt gacgaacaga tgagcaaaca agttcgtgaa agtgaattgg aagcttttaa
    47401 acaagaagca gaagagcaaa tccaatattt gaatgtcaca ccagcacaac aacaaatgat
    47461 tcgctactta gtggatcaag gtatcgtagt gaatgacgta ttgaatgaga aaaagacaga
    47521 agaattgaaa caatccgcac gagaagctgt acagccagtg atgatcttcc aaggagaaat
    47581 cattgttcgt gaaggtaatc aaatcgatgc ttcagctatg aaaaaattgg aattactagg
    47641 actgactaat caaacaactt cgatttttcc gctaattgcc atggttttag ctgttttgct
    47701 tcaaatcggc gtactgattt ataattcact tcaattccaa aatgcaggag aaagaacaaa
    47761 atacgtgctt ttctatgtga cagctatgtc agtcagcata gtgctgatga aatttttcca
    47821 attattccaa acggaacaag ctacttatat cccgctgttt tatcccgctg cttttgcacc
    47881 acttgtttta agctttttct tgaatcgaag agcagggatc atggctggta ttttccaagc
    47941 agtatccgca cttttcattt tttatgattc gattggcacg aactttctaa cgattatctt
    48001 gatgtcttat gttttctctg ggctcatggc aacgattgtc agacgcaaac ggatctcaga
    48061 acaaggatta tctgctgcca tgtgggtcat tatttttcct gtgatgatgg atgtcatttt
    48121 gatcgtctat caaggaatga gctttggtga tgcaacgact tggttaatgc tcgtctgcgg
    48181 gttcactggt gcactcttct cattcttgct gacgatcggt ctacacccat atattgaatt
    48241 gatggtcaat gatgacagtg taattgtatt aaatgaactc agcaatccaa atcatccttt
    48301 attgaaacag ttgctggaag aagcgccagg tacttatcat catagtatga tggtagctaa
    48361 tctaagtgct aacgctgtag cagaaatcgg cggacgttct ttgctaactc gagtagcttg
    48421 ctattatcat gatatcggca agatcaaaca tgctagcttt ttcgttgaaa acttgccttc
    48481 aggagcggaa aacccgcaca atttcttatt gccagaagac agtaaacata ttatctttgg
    48541 acatgtgaca gatggagcca aaatattgga agattataat atgccgcaaa tggtgatcga
    48601 tatttgcaaa cagcatcatg gaaccacgct aatgcgttat ttctacatca aagcgaaaga
    48661 acgcaatccg gaagtaacag aagagcaatt ccgttatcct ggaccaaaac cgcaaagtcg
    48721 tgaagcaggg atcgtcaata ttgctgacag ttgtgaagct gcagtacggg caatggatca
    48781 tccgacgagc gaaaaaatcg aaagttttgt ccataatctt atcgaagagc gtatttccga
    48841 tggtcaatta gacgatagtg gactgacctt gaaagaaatc cgaaaagtgg aaaaatcatt
    48901 aatcagcggt ttaagtagca ccttccattc tcggatcaaa tatcctaaaa tgaaaacaga
    48961 agttgagaag ataaaggaag aacaagaaga atagaaagaa gcgatgtata atggatatta
    49021 cctttatgga tgaaacaaac caagtctcag aagagaaaat gaaagaaatc gatgacttgc
    49081 tgcaatttgc agcatcttat ttaaagctgc cagaggaaac agaaatgtct gttactttca
    49141 tggacaatgc ggcaatccaa gtaatcaatc gtgattaccg tggaaaagat gcaccgacag
    49201 acgtcatcag ttttgctctg gaagaagaag gcgaagacga aatcccagtg atttttgaag
    49261 atggagagaa tccattacct cgtgtactag gagacatcat gatctctatt gaacgtgctg
    49321 ctgaacaagc agaagcttac ggccattcat atgatcggga acttggcttt ttagcggtac
    49381 atggattctt gcatatcaac gggtatgacc atatgacacc agaagatgag aaagaaatgt
    49441 ttggtttaca gaaagagatc ttggatgcct atggactcaa aagataaaaa cgtagagaaa
    49501 aacaaacatt tcctgatgtc tgtggaattt gctgtccaag gagtcaaaac cgtttttgag
    49561 gaagaacgca atatgaggaa acatgttgcg ttcggtattc ttgctttatt tatgggcgtg
    49621 attttccagc ttgatcggat agagtggtta tggctgcttt tagctgtttt tctcgtttgg
    49681 atagtagaga tcatcaatac tgtttttgaa aatgtagtgg acatgtttac ggattttcat
    49741 tttcatccga ttgggaaaaa aatcaaagat atggcagctg gagcagtttt agtgaccgct
    49801 tgttttgctg tcatcattgg gttgatttta tttgtcccta aaatatatca tttgttgttt
    49861 aattaaaaag gagaacgtat atgccagaac ataaatcagg gtttgtcgca atcgtcggcc
    49921 gcccgaatgt aggaaaatcc acattattga accgaatcgt gggtcaaaaa attgccatta
    49981 tgagtgacaa ggcacagaca actagaaata aaatccaagg agtatatact acaccagaag
    50041 ctcagctgat ttttatcgat acaccaggaa tccataaacc aaagcatcgt ctaggagatt
    50101 ttatggtaga agcagcttac agtgcgttga aagaagtgga tgcagtctta tttatgatca
    50161 gtgctgatca aaaacgcggc cggggagacg attttattat tgaacgtcta aaaaacgtgc
    50221 attctcctgt ttatctgatt atcaataaaa tcgataagat ccatccagac gagttgctgg
    50281 gaatcatcga agattattcg acgcagatgc cttttgcaca agtgattccg atctctgcta
    50341 cagaaggaaa caatgtcgaa cgcttaatgg atgtattagt cagtgaaatg ccagagggcc
    50401 cacaatattt tccagatgat caagtgactg atcatcctga atacttcatc gtttctgaat
    50461 tgatccgtga gaaagtcttg tttttaacac gagacgaagt gcctcattct gtcgcagtcg
    50521 ttgttgattc gatgaagcga aacgagaatg ataaaatcca tatccaggcc acgatcatcg
    50581 tcgaaagaga tagccaaaaa ggaatcatta tcggcaaagg cggaaaaatg ctgaagcaag
    50641 taggaacgaa agcaagaaag gatatcgaaa atcttttagg agacaaagta tttctagaac
    50701 tttgggtcaa agtccaaaaa gactggcgag acaaaaaagt ctatctgcaa gacttcggct
    50761 accgaaaaga tgaatactga tattctgaac ttcttatagg ttaagtatag aaataaactg
    50821 gataaaaatc cgcacgttga gaaaaacggc ggaagatcga aacataaata atctggatcg
    50881 gcagaatctg cttttccaga tttatttttt aggagggaga atatgagcca gcttgcagaa
    50941 tcgaaaggct tgattttatc tagccgtaat tacaaagaaa aagataaatt agtcaaaatc
    51001 tttacggaat cttctggcaa aatgatgttt tatatcaaag gaatccatcg gcaaaatcag
    51061 ccattagctc cggctttgct cccctttacc gaagcagtct atatcggtaa ttttcgaagt
    51121 gaaggtttgt cgtttttaag cagtgtcaaa gacgtccatg cgtttcggaa catccaagaa
    51181 gatatctttt tgagcggtta tggtacctat ttgctaaatc tagtagatgc agcaatcgaa
    51241 gatcatcaat atgacccgca tttattccaa tttacgcaac aagctctgca gcggatggat
    51301 caaggagatg atgcagaaat catcacgaat atctttgaag ttcaaatact gcaacgcttc
    51361 ggaatcgcgc caatttggac tcactgtgtc gtatgcggag aaacaaaagg aaaatttgac
    51421 tattcttcca aatatggcgg tgtgatatgc gagaaacact ggccaatgga cgaacaccgt
    51481 tatcatgcag atcctcgtgc tgtttatttc gtccgaatgt tttcggctat ttcttatgat
    51541 aagatcagtg gaatccactt gaaagaagaa acgaagcagg caatccgtga cctcattgac
    51601 cagttgtatg atgaatatgt cggtattcat ctaaaaagca aaaagttcat tgatcaaatg
    51661 aagtcttggg cacacgtatt aaagacgcca gagaaaaata tgcctgaaaa agagatacct
    51721 gaaaaagaag aataaatgaa agatacaaca aaaaaatcaa aactatttga caaatacagg
    51781 gacttccgtc tattattaac cgtagattaa atagatcgtt cactgagagg atctattata
    51841 taaacaagaa aactgcaaaa tgaatacgta cattgaccaa gatcagtaaa aaacacgtgg
    51901 tttagcgagt tcgggagagt ggaagccgga cccaaacgat ttttgaagag gcacttgcga
    51961 gtacgataaa tgaagctgcc gaatctttat tcggaagtag ggtggaaccg cgaaattatt
    52021 cgtccctatg tctgtaatca gacataggga ctttttgtcg ttttctttcc tgtattctta
    52081 ttgacagcaa cgcttaaaaa ttgaaagggg caaaacagat gagtaaaaaa ttgaccgtcc
    52141 aagatatgat tttaacatta caaaaatttt ggtcatcaaa cggctgcatg ctgatgcaag
    52201 cttatgatac agaaaaagga gcaggtacga tgagcccata tacattctta cgggcaatcg
    52261 gaccggaacc atggaatgct gcttatgtag agccatcccg ccgaccagct gacgggcgtt
    52321 atggagaaaa cccaaaccgt ttgtatcagc atcatcaatt tcaagtcgta atgaaacctt
    52381 cacctgaaaa tatccaagag ctttatttag aaagcttgcg tcttttagga attgatccat
    52441 tagaacacga tattcgtttt gttgaagaca actgggagaa cccatcgatg gggtgtgccg
    52501 gtgtgggttg ggaagtatgg cttgatggga tggagatcac acaattcacg tacttccagc
    52561 aagtcggagg actaccttgt aaaccagtta cttctgagat cacttatgga ctagaacgtc
    52621 ttgcttcata tattcaagaa gttgaaagtg tctatgatct ggaatgggct gatggcgtga
    52681 aatatggcga gatcttcaaa caaccagaat atgaacattc caaatattct tttgaagtaa
    52741 gcgaccaaga cttgctacta agtaattttg accgttttga aaaagaagct aaacgctgta
    52801 tcgatgaaaa tcttgttcat ccagcgtatg attatatttt gaaatgcagc catacattca
    52861 acttattaga tgcccgaggt gcagtatccg taacagaacg agcaggttat ctttcccgta
    52921 tccgcaacat ggctcgtgct gtagccaaaa tctttgtggc agaacgcgaa aaattaggat
    52981 tccctttatt gaataaaaac acagcaaatc cagaaaacat gaaggaggct gaataagatg
    53041 gcaaaagact tattacttga aatcgggctg gaagaaatgc ctgctcatgt tgtcacacca
    53101 agcatgaaac aattagaaga aaaaacagca aaatttttag atgaaaacca attgacttat
    53161 gatacgatcg aaacattttc cacaccgcgc cgtttagcaa tcaaagtaac aaatattcca
    53221 gaacgacaag cggacagcga agaagaagtc aaaggaccag ccaaaaaaat tgctttggac
    53281 gcagatggaa actggacgaa agcagctgaa ggatttgtcc gaggacaagg tctgacgaca
    53341 gatgctatca cttttagaga attaaaaggc gtggaatatg tctatgtaac gaaatacact
    53401 cacggcaaag aagcaaaaga agtattgaca ggtttagcag atgtcattaa aagcctcact
    53461 ttcccagtaa cgatgcattg ggcagaatac gattttgaat atatccgccc tattcactgg
    53521 atcgtggcat tgttagatga cgaagtaatc ccattcgaaa tcttggatgt caaaacaggc
    53581 aaagcctctc gaggtcatcg tttcttaggc gaagatgtaa catttacgca tgcaaaagaa
    53641 tacgaagaaa aattaaatga acaatttgtt attgcttcac cgcaaaaaag aaaagaaatg
    53701 atcatcacac aagcaaacga attagcagaa aaaaatcact ggatcattga tctagatgaa
    53761 gatttactag aagaagtcaa caatctagtc gaatatccaa ctgtcttttc tggcgacttc
    53821 gaagaaaaat atctatctgt tcctgaagaa gtactagtca cttctatgaa agaacatcaa
    53881 cgttatttcg aagtacggaa cgatcaaggt atgttgcttc ctcattttat ttctgctcgt
    53941 aatggcgatc gggtaaaatt ggaaaatgtg gtacgaggca atcaaaaagt attgactgct
    54001 cgtttagaag atgcggaatt cttttataat gaagacaaga aagcttcaat cgaccaatac
    54061 gttgaaaaat taaaaactgt tactttccat gaaaaaatcg gtagcatcta tgagaaaatg
    54121 caacgggtac aagtcatcgc tcgcatcata ggcgaacaag taggactatc tgaggaagaa
    54181 ttgatggatc tgcaacgcgc tgctgaaatc tataaatttg atctagtaac caacatggta
    54241 ggagaattcc ctgaactaca agggatcatg ggagaaaaat atgctctgct taaaggcgag
    54301 aaaccagccg tagcaacagc gatccgtgaa cattacatgc ctatatccag tgaaggagat
    54361 ctacctgaga ctacagtagg ttctgtttta gcgattgctg ataaattaga tagtatcttt
    54421 tctttctttg cagttgggat gatcccaagt ggctcaaacg atccatatgc tttgcgccgt
    54481 caagcatatg gtgtcgttcg aatcatcgaa tcgaaaaaat gggcctttcc tttgtctgtt
    54541 ctgcaagaaa cgattagtga agttatcagt aaagatacgg atcgttttgg cattggcttg
    54601 tcagcgggac aacaacaggt gatcgacttt atcaaaggcc gtctgcgcca attattgaca
    54661 actaagaata ttcgtcatga tgtcatcgaa gctgttttga acgcagaaca aaaagatctg
    54721 acaaaagtat ttgcagcagc acaattgttc aagcagcatc ttgcagatga agacttcaaa
    54781 ccatcgatgg aagctttgac acgtgtcgtg aacttagcga aaaaagcgga gcttgaaaaa
    54841 caatcagaag tagaccctga actgttcgaa aacgaagcgg agaaagaact gcacaaagca
    54901 gtagaggcaa tgaaaacaag ctttgctgac caaacgatca acgaaaatta tgatcagctt
    54961 gtaagccttc gcccactgat cgaaaattat tttgatcaga cgatggtcat ggcagaagaa
    55021 ccagcagtac gtaagaaccg attaacgcaa ttaagtcaaa ttgctgccat ggctttgtca
    55081 ctagcaagtt tagatcaaat catcacaaaa taatttctaa tatgtaaata aaccagagaa
    55141 caggcacaaa ataggctatt tctctggttt atttgttata aatataaata actattatta
    55201 attcaatgtt aatttttttt gttattttat tttttgtgta acttttaaaa acacctatga
    55261 aaattaagga aataaaaatg aaatcgatta attgttatct tattaatgtt ttatttattt
    55321 ttaaatcgta aattgcccta gtcaagaaaa cagtttgtgg tatgattata tagggaaaac
    55381 ttgtttacaa atatttctgt gaatatatta gtttaattat gttttttaaa ataaaaagct
    55441 gtcattttta tgtaagtgaa ttatatctta atttatctat catcaatact taggagtgaa
    55501 tctatggaaa agccattcgt caagtcattg actgctgtgg cggtaggtgc aggtgctatt
    55561 gcgatctgtt tgtttggtta ccatatcaat aatcagcggc aacatcagca acggatcaat
    55621 tatgcagaat ctgccatcac caatcaaaaa gacaccttga cttctttatc aaaagaagta
    55681 gacaagctgt atagtacaaa agaaaaaaat tttctaaacc ctgaaataac agaagaaaca
    55741 atcacaagtt tgtcaaataa gctatcctct gtcaaacttt cagcagatga ttacgacatc
    55801 aaagaatcag aattgcctaa agaagctgtt gcaatccaag atgagaagaa agcaatcgtg
    55861 acacagttag atagtgcaga atcaaaactg aagatccaga cagctgtcaa cgatttattt
    55921 actaaaaatg tatcaaactg gcagcaagct gtagacgatg tcgtcatcaa agaaaaggtg
    55981 acaagtgcag atgtcgctcg tgtacgtgaa aatatgagct tttttaaaga tagtccttgg
    56041 aaaacgattg ttatgcaata tctaggattc gctgatactc agatcgcgca agtcacgcaa
    56101 ctagatcagt tattcgatac gatgttgaag gatggtcaag tgactgccac cgctacttac
    56161 gatcaatatt tgacggtgct cagtcaaata gatcagatcc ggaatgaaaa aatacgcgca
    56221 gcatacgcaa caaaagcaca aactgttgct cagcaaatgg gctatagcaa tataagctat
    56281 tgacagttaa aacgttgatt caagcaaggt tagcaaacgg aggaaactat ggcaagacga
    56341 agaagaaaat caagagggaa aaaaatattt ctgattattt tagcagttct tatcgtatta
    56401 gtattagcaa ttgtaggagt aggagcaaaa ttatatctgg atctctcaca ttctattgag
    56461 aaaacttacg aatcagtgga acgaacccaa ggagaacgaa cgaaaccagt tgatctggac
    56521 aaacaagaat ctttctctgt tctattgatg ggcattgata ctggagattt aggtcgggtc
    56581 gatcaaggaa gatcagatac gatgatggtt gccacagtca gtcctgaaga caaacagaca
    56641 acgatcgtca gcattcctcg agatacgtat gtcgacatcg taggtcgtga cacaaaagac
    56701 aagatcaacc acgcttacgc attcggcgga gctgccatgg cgatggatac cgtacaaaaa
    56761 tatgtagaca tcccaatcga tcactatgtc tctatcaaca tgaaagggct aaaagaactt
    56821 gttgatgcag ttggtggtat cgaagtcaat aatgacctca ctttctcaca agatggctat
    56881 gactttacaa tcggtaaaat tactttgaac ggggatcagg cattatctta ttctcgtatg
    56941 cgttatgaag atccaaatgg tgactatggt agacaagagc gtcaaagaaa gatcgtagaa
    57001 ggtgtagcga aaaaagtatt gagtctaaac ggtgtcagca actatcaatc cgttttgaat
    57061 gctctagagt cgaatatgaa aacagacatg agctttgatg aaatgaaaaa aattgcttta
    57121 gattatcggg aggcatttgg tacgatcaag caagatcagc tgcaaggaga aggcttcatg
    57181 caagataata tctcctatca aaaagtcagc gatcaagaac ttgatcgtgt gaaaaaagaa
    57241 ttaaaagatc aaatgaatct agagaataaa taggaaagtg gagaaaaaat ggaagagaca
    57301 atcagcttga aagaaatttt tgaaacatta cgcaaacact tggtaacaat catcatctca
    57361 atgtttgctg gcttggccat ctcaggaatc gtaacatttt tcatcttgac accaaaatac
    57421 agttcacaag cacaattgat cgtgacactg ccacaatcag acacagcaaa tgtcaatgat
    57481 gtcaatacga acctgcaaat gatcaatacg tataaagata tgatcgtcag tgatttagtg
    57541 ctaaatgaag tcaaagatcg tttagaaaca gaagacaatg tgaaaatgac tgctgaacaa
    57601 atcaaagagg ccatctcagt caatcagtca caaaattcac aaatgttctc gatccaggca
    57661 ataagcacga atgcagtgac tgctcaacag atcgctaaca caacttcaca agttttccaa
    57721 gagaacgcaa aagacgtgat gaatgtcgat aaaatctcga ttatttcagg tgcagttgcc
    57781 aatacgacac ctgtttcgcc aaataataaa ttgaatttag tgattggctt agtattagga
    57841 atgatggtag gcgtaggtct ggcattctta ttcgaattac tcgatcggac agtgaaagat
    57901 gaaaaatatg tgacggatac attaggattc ccaatcttag gaacagttcc agaaatgtca
    57961 gcgaaagaat tgaacgctgg tatccgtaaa aaaggatcag ctcctgcacg accaaaagct
    58021 acaaatggta aaacagcgcc atcacgcaga agccgctcaa gagtctagga ggaagaaaaa
    58081 tggcacgaac acagaaacaa aaagcagcac aaactcatgc agtcagtttg atcacattaa
    58141 caaacccatc ttcaccaatc gccgaacaat atcgtacgat ccggacgaat atccagtttg
    58201 cctccgcagc tggtcagcaa atcaaaacga ttgtcgtgac ttcatcaggt cctggagaag
    58261 gaaaatccac cactgcagca aacattgcag tcgtttttgc taaatccggt caacgggttc
    58321 tattagtcga tgcagattta cgtaaacccg tcgtctataa aacattccag ttgagcaatg
    58381 ctagtggatt aagtacagca cttagttcat caggaagtgt agcagatgtg atccaacgaa
    58441 cgccagtcga gaacttgtcg attttgccta gtgggcctaa gccacccaac ccatcagaat
    58501 tgttaagctc gccaagaatg gatcagattc tagccgaagc aagacagata tttgacgtgg
    58561 tgatattcga tatgccacca gtagtagccg taacagatgc acagatcatg tcttcaaaaa
    58621 cggatggcac tttattggtc gtacgtgaaa atacatcacg taaagaatcc ttgtctaaag
    58681 caaaagaact gctagagatg gtacaagcac gagtcttagg tgttgtatac aacggagcag
    58741 aacatagcaa agatgctggt tattactacg gaaattaagg aataagaaga gaggagacaa
    58801 gagaaatgat cgatctacat tgccatatcc taccaggaat cgatgacggg gcagaaaact
    58861 tagaagcaag tattgcaatg gctgaaaaag cgattcagca aggcatcacg catattttat
    58921 gcacaccaca ccacaataat ggaaaataca gcaatgaaaa atcacaagtc atttctctag
    58981 tcgcttcgtt acaagccgaa ttagagaaaa gacaattgcc tttgacgtta ttggaaggac
    59041 aagaagtacg tattaccgga acgctcatcg aagacatcca ccgagatgaa attttattta
    59101 cagatttaga tgatacatat cttctgatcg aatttccgac actggaagtg ccgttatatg
    59161 cagaacggct tttttttgag ttgttagaac taggaaagac accagtgatc gtccatccag
    59221 aacgtaacgc gcattttcgt aaaaacccga attatttgct tccgttccta gatatggggt
    59281 gtttggccca acttactgcg ccaagttatg ttggggtgtt tggcaaagac atccagaaaa
    59341 cagctaaaac gatggtcaaa cataatctcg tgcagatggc tgcttctgat gcccatgggg
    59401 tctctaagcg caccttttac ttaaaagagt gctatgagca gattggcaag gactttggta
    59461 aggaaaaagt agtacagatg aaacaagtcg caaaggatct gatcaacggg gatgaaatca
    59521 gttatccagt ctatgaagag gtaaaaaaga agaaatttgg tttattttag ggggaatgta
    59581 gggtgtttgt attaacaaga agaagaaaaa ttgccacatt ggttgttgtg gacagcttgt
    59641 tattaatcgc tgcaaatatt gcagcagcta aattcatgaa gccgtttgta gctataccaa
    59701 tggaccttat tttaatctct attggtttgt cgattggttt ttatttattt tatggtagtt
    59761 tatttaaagt tttcactcga atcaatcgct atacaaattt aagagagatc attgcaattt
    59821 ttagttcact atctgcaagt gctgcctcaa gtatcctcat actgctgttc attaatcggc
    59881 gatacagttt acggttagtt atctttgctt atctgctttc gctcttattg atcatcggta
    59941 gccgattgat ctggcgtatc tacatcgaaa caaaaaatat gagatatgta tcagcagatt
    60001 ctgctaaaaa tacattgatt gttggtgctg gcgaaggcgg gcgtatttta tacaacagct
    60061 ttcttggatc caaaacggct caagatatcc acgttgtcgg gttcgtagat gatgatccaa
    60121 ataaaagaaa tacgtatctt tcaggaaaaa aagtattagg tgcattaaaa gatattccgg
    60181 aattgattga aaaatatgac attcaaatgg taacgatcgc tatcccttcc ttatcaagaa
    60241 aaaaattacg aagaatcttc gagttagtcg aatccgctcg tgtgaaagtc aacacgatgc
    60301 cttctataga agaacttgct tcaggaaaaa ttagcgtatc aaaattaaaa acaattgacg
    60361 tagtggattt actgggaaga gatgaggtaa agctggatat tgaatccatc aaagatcaga
    60421 tcacagacaa agtcattctt gtcaccggcg caggaggatc gatcggttca gaaatctgtc
    60481 ggcaaatcat tcaattcaat cctgcaaagc tattgctttt aggacatggg gagaactcga
    60541 tctacttgat tgaccgtgag ttacgcacgc atcatcaaaa ttgtcctaca gaaatcgtac
    60601 cgatcatcgc agatatccaa gatcgcgaga aaatcaatga gatcatggaa caatatcatc
    60661 cagatatcgt ctaccatgca gctgctcata agcatgtacc actgatggaa tataatccaa
    60721 aagaagcagt caaaaacaat attttcggta caaaaaatgt agcagaagca gctaaagcag
    60781 caaaagtgaa aaacttcgtc atggtatcga cagataaagc taacaatcct ccaaacgtca
    60841 tgggttcaac aaaacgaatc gctgaaatga tcgtgactgg attgaatgaa gaaggctgta
    60901 cgaaattctc agctgtcaga tttgggaatg tccttggttc tcgcggtagt gtgattccag
    60961 tattcagaga acaaattgct caaggtggtc caatcactgt aacagacttt cgtatgaccc
    61021 gatacttcat gacgattcct gaagcgagtc gtttagttat tcaatctggc gcattagcaa
    61081 aaggtggcga aatttttatt ctagatatga gtgaaccagt gaagattgta gacctagcca
    61141 aaaacatgat ccgattgagc gggtatagcg aagacgaaat cgaaatcatt gaaacaggta
    61201 tccgtccagg ggaaaaacta tatgaagaac tattgttgga taaggaaaga aatgatgaag
    61261 cagtttatga gaaaatcttt gtaggaaaca tcaaaggtta ctcaatacaa aaagtgatgg
    61321 attttgttaa gagcctgcca caagacgatg aacaactggc taaagacatt gtcacttttg
    61381 caaatgcttc gaatagatag gagattaaaa attgaatatt ttaatattaa gttgtggacg
    61441 tcgttgtgaa ctagtgaatg catttaaaac agcattaaac aataatgaaa tggaaggaaa
    61501 aatcattgga gcagattgct ctgaactagc acccgcacta tatatgtgtg acgaaaaaat
    61561 agtattacct aaagtttcag aaagtaatta tattgaggaa ttaataaaag taataaagtt
    61621 ttttgaaatt aaattaattg ttcctactat tgatactgaa ttatcaacat tatcaagaaa
    61681 taaaaaatat attgaaaatg aaacagactc agttgtatta gtttcttcag aaaaagtcat
    61741 cgacatttgt gagaacaaaa ttttaacttc tgcttttttt gaacaaaatg gttttaaaac
    61801 tcctgaaatt ttaaactctt ctgaaattac aaaatttcct gtatttataa aacctctgaa
    61861 tggtagttca tctgttaaca catttattgt aaataatgaa aaagaattgt tgttttttag
    61921 tgaatatata gataatcctc ttattcaaga gtatatttta ggtgaagaat atactataga
    61981 tgtttgctta aactttgatt cgacaccagt aagtattgtt cctagaaaaa gaatagcaac
    62041 tagaggtggg gaaatactga agggtcagat tattaaagat agagaactaa ttgagactac
    62101 gaaaaagatg ttggaaaaat taaatgcaat cggacatatt actattcaat gtataaaaaa
    62161 cgaaaaggga atattttatt tagaaataaa tgcaagatac ggtggaggag cccccattag
    62221 cattaaatca ggagctaatt cccctgaata tattataaag atgatagatt caaaaaaaaa
    62281 tttgagatac agagaaaatt atttagataa aatgatagca ctgagatatg atcaagcgat
    62341 ttatttagat gaaaaaggaa atgtatataa tgattaaagc ggtgatcttt gatttagatg
    62401 acactcttgt gtctgaatat gattatgtaa aaagtggata caaatgtgta gctagaagat
    62461 tagcagtgca aaaaattttc ccggctactt ttgacgaaat atatagagtc cttttagatc
    62521 tttttgctga agatagtaaa aatgtattta atcgtctata tgactatttt gaaattcctt
    62581 atagtaaaaa agaaattaaa gaactggtaa atgtatatcg agaacacaaa ccagacataa
    62641 attttttaga aaatgcagat actttattaa cggaattaag aagtagagga tacaagctgg
    62701 ggattattac agatgggtat gctataaccc aacgaaacaa attggatgct ttgaaagtag
    62761 actatttggt agattatatt tgtattactg acgaattagg ccgtgaattg tggaaaccac
    62821 accctatctc atatctttta ttgttagaaa agtttaattt aaaggcacaa gagtgtatat
    62881 atattggcga taatgagttg aaagatttta taactgccaa atcaatagga atgcaaacaa
    62941 ttaaaataga aagagtaaat ggtatttaca gagaaagcag tttgaagttc aaaagatttt
    63001 accaagctga taaaaaaata cgttcgttat gggagataaa aaattttttg ggagtgattt
    63061 catgaaaagt aaaagaattc tattagcttc tccacatatg agtgaagaag gatatgaaaa
    63121 agagtatgta aaagaagcat ttgatacaaa ttgggttgct cctttaggtg cgaatgtgaa
    63181 tggatttgag aaagaattag cagaatacgt gggagctagt catgctgccg cattatcttc
    63241 tggaacagca gctatacatt tagctttgaa agcggctggg gtcggtaaag atgacatagt
    63301 gatttgtcag tccttgacgt tctcagctac tgctaatcca attctctatc aaggagctat
    63361 acctgtattt gttgatagtg attacgaaac ttggaatatg aaacctgaac atttgcgaac
    63421 agcactagaa aaatatccta acacaaaggc tgtattagta gtacatttgt acggtttatc
    63481 agctaattta gacgaaatta ctaaaatatg caaagaatac gatgttactc taattgaaga
    63541 tgctgcagaa tcattaggaa caacatataa aggaaaatat actggaacat ttggcgacta
    63601 tggaatttat tcttttaatg gaaataagat aatcacaact tcaggtggcg gaatgcttgt
    63661 atccaatgac aaagaaaagg tggaaaaagt gagattttgg gctacgcaat ctcgtgagaa
    63721 ggcacgccat tatcaacaca atgaaattgg ctataattat cgaatgagca atatcgttgc
    63781 tggtatcggt cgaggacaat tgaaagtatt aaatgaaaga attgagaaaa aacgatatat
    63841 tcatagtttt tataaaaaag aattgtctaa attgtcaaat atacaattca tgccagaaaa
    63901 taattggaat gaaccgaatt attggttaag tgtcataaca ataaagggaa taaatgcgaa
    63961 tcatcttatt gatgagttag acaaaaataa tatagaagcc cgcccagtat ggaaacctat
    64021 gcatttacaa cctgttttta aaaattatga ttatattggc gatgatgtag cagaaacttt
    64081 atttgactta ggagtatgtt taccatcaga tacaaagatg acagatgaag atttaaaata
    64141 tgtagtatct acgattaaaa gagtgatcaa tgatgcgtaa aaaaactttc tatcagcttt
    64201 ttgggaaaag aattttagat atcctattgt caggaattgc tctcatcgtt ttatcgccga
    64261 taatcttaat tgtaggtttt ttagtaagaa ttaaacttgg ttctccaatt atcttcaaac
    64321 aagaacgacc aggaaaaagt gaaaaaattt tttccatgta taaatttcgt acaatgactg
    64381 acgaaagaga ccacaatgga gaatatttac ctgatgaaat tcgactaact aaatttggga
    64441 aaatgcttag agcaacaagt ctggatgagc tacccgaact ttggaatatt ttgaaaggtg
    64501 atatgtcgat cgtaggacct cgtccattat tagtggagta tttgccacta tatagtgaga
    64561 agcaacggaa aagacacaac gtaagaccag gattaactgg actggctcag gtcaatggaa
    64621 gaaatgctat tagttgggaa gaaaagtttg atttagatgt ttattatgtt gataaaatta
    64681 gtttctttaa tgatcttatt attataattc agacatgtaa aaaagtaatc aagaaagaga
    64741 atattaatac aatcaataac aatatcccag aaaaatttaa agggagttaa atacagcagc
    64801 ttaatgcaag ttttgtgact tgcattatat ttaggtataa atcaaagcga gtatattaga
    64861 attatataac atatgttaaa aaaacgtata gctaataaaa gtatgatttt aaaaatttgt
    64921 gtagagtttt aaatatactg tttcaatacg agaaaattat aaaaaagtat aaggaaaaga
    64981 gagttatggc aaagtattat aataaaaaaa ttcttataat ggcaaacaac gatgatggtc
    65041 tttaccgttt tcgaggaatg ctcataaaaa acttagtaga tcaaggtaat gaagttattg
    65101 tatctcttcc aaagggcaag aatattccta aattaattga acttggatgt caaattattg
    65161 aaactccaat agatagaaga ggaattaatc caaaaactga ctttaaacta ttttttaact
    65221 attgtaatat tttgaaaaaa ataaagccag atatggtcat tgcttatact atcaaaccaa
    65281 atatatacgg tggattggca tgtcggttaa gaaaggtttc ttatgcatta aatataaccg
    65341 gattaggaac ggcatttcaa aaaaaggggg ttttgaaaag tctcattgta tttttgtata
    65401 gattagcagc taaaaaatct aaggtcatat ttttcgaaaa ttttgaaaat atgaaaacat
    65461 ttcagacttt acaaattgct aaacaaagta aatacaagct attaaacggt gcaggagtag
    65521 atgtagaaca ctttagttat ttagaatatc ctaaagatga gcaagttcat tttttattta
    65581 ttggaagaat tatgaaagag aaaggtgtag atgaactttt tgaagcaatg aaaaacttat
    65641 atagtgaaga gaaaaattgt gtacttgatg tccttgggta ttttgaagaa gattacggca
    65701 taaaaattga aaaatacgaa aaagagggat ggttaaaata tcatggatat caatctgata
    65761 ttcgtccctt tgtagaaaga gcacattgct ttgttttgcc tagttggcac gaaggaatgg
    65821 caaatactaa ccttgaatca gcagcatcag ggagaccaat tattacaagt gatatcccag
    65881 ggtgtaaaga agcagttatt gaatcgaagt ctggttattt atgtgaaaga aaaaatagtt
    65941 gtagtctcta taattcgatg aataaatttc taaaattatc atatgagcag cgcattaaca
    66001 tgggaaaaat ggggagaaat tatatgatta aaaaatttaa taagaagaaa gttgtcgatg
    66061 aaacaattaa atcattattt agttaaaaag atatgttttg caaagtatgt gatagaaaag
    66121 agggattctg tggcttcaga atagatatca aagaattggc aaaagtttct gatatttttt
    66181 tatttactac attacaagaa ggaatgccaa gatctatgat ggaagctatg gcaagtggat
    66241 tgccatgtat agcaagtaaa atccgaggta atgtagacct tttagtggaa ggaaaaggtg
    66301 gatatcttgt tccagctaaa gatgcagaat tagtagcaga gtgtttgaga gaactaatca
    66361 ataataaatc tcttagaaag tatatgggaa atgagaacct ttccagaatt aaagaattcg
    66421 aggttagtat cgtaaaaaaa agaatcaaag aaatatatga agaagttata ggtgagagtg
    66481 taaaatgaaa aatccaatgt tttcaataat agtacctatc tattgcgttg aaaaatattt
    66541 gaaagattgc ttagattcaa taagaaatca gacatttaaa aattttgaag caatactagt
    66601 tgatgacggt agtcctgacg aatgcccaga aatatgtgac tattattccc aaatagatgg
    66661 acgtttaaaa gtaattcata agaaaaatgg tggaataata gatgcacgga aaataggagt
    66721 cactagtgct atgggagagt atatagtttt tctagatggt gatgattggc ttgcaaatac
    66781 ttatttagaa aaatatgcgg aagtaattac taagtacaat ccagatataa tatgtagtgg
    66841 gtattttgca tcacgttcca acaaaattag aaaaagagaa ttgtcttgct cgtttggata
    66901 ttatgacaaa aataaaatta taaatttgat ttatcctaaa ttaattgagg atgaacatgg
    66961 agaatatttt agtccacaat tatgggcaaa agcttttaga actactctgt acaaggagca
    67021 acaacaagta tctgggcaag ttagtgttgg tgaagatcat gcatgtacaa aaccatgtat
    67081 ttaccatgca aattcgatat atatgatgga aaaatgttta tattattaca gaataaacga
    67141 aaattctata acaaaaaaac cacaaccata ttattgggaa ggaccaaagg ctattggaga
    67201 gcattttgaa aagcagattg atatgaataa gtatgatttt caagatcaag tatatagaaa
    67261 tgttacacac aatttattta atgttgctgt ttcacaattt aataaacagg acaaatattt
    67321 aaatataaaa aaagatatta tacaaaatct aagtgacgaa tactatacta gagctatttg
    67381 taaatgcaaa tataaagata attggaaagg a
//
LOCUS       DAXLPY010000006        66578 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.006, whole genome shotgun sequence.
ACCESSION   DAXLPY010000006 DAXLPY010000000
VERSION     DAXLPY010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 66578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.006"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..1283)
                     /locus_tag="ACF3UF_000449"
     CDS             complement(<1..1283)
                     /locus_tag="ACF3UF_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3670605.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKG"
     gene            complement(1581..2516)
                     /gene="murB"
                     /locus_tag="ACF3UF_000450"
     CDS             complement(1581..2516)
                     /gene="murB"
                     /locus_tag="ACF3UF_000450"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFD3670606.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2589..3509)
                     /locus_tag="ACF3UF_000451"
     CDS             complement(2589..3509)
                     /locus_tag="ACF3UF_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3670607.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3622..4374
                     /locus_tag="ACF3UF_000452"
     CDS             3622..4374
                     /locus_tag="ACF3UF_000452"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFD3670608.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5238..5771
                     /locus_tag="ACF3UF_000453"
     CDS             5238..5771
                     /locus_tag="ACF3UF_000453"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFD3670609.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6261..6785)
                     /locus_tag="ACF3UF_000454"
     CDS             complement(6261..6785)
                     /locus_tag="ACF3UF_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFD3670610.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(6778..7251)
                     /gene="tsaE"
                     /locus_tag="ACF3UF_000455"
     CDS             complement(6778..7251)
                     /gene="tsaE"
                     /locus_tag="ACF3UF_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFD3670611.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7374..8354)
                     /gene="pta"
                     /locus_tag="ACF3UF_000456"
     CDS             complement(7374..8354)
                     /gene="pta"
                     /locus_tag="ACF3UF_000456"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFD3670612.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8507..9187)
                     /locus_tag="ACF3UF_000457"
     CDS             complement(8507..9187)
                     /locus_tag="ACF3UF_000457"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFD3670613.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9313..10182
                     /locus_tag="ACF3UF_000458"
     CDS             9313..10182
                     /locus_tag="ACF3UF_000458"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3670614.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10208..10723
                     /locus_tag="ACF3UF_000459"
     CDS             10208..10723
                     /locus_tag="ACF3UF_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFD3670615.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(10770..11333)
                     /locus_tag="ACF3UF_000460"
     CDS             complement(10770..11333)
                     /locus_tag="ACF3UF_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3670616.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11388..11567)
                     /locus_tag="ACF3UF_000461"
     CDS             complement(11388..11567)
                     /locus_tag="ACF3UF_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670617.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11644..12153)
                     /locus_tag="ACF3UF_000462"
     CDS             complement(11644..12153)
                     /locus_tag="ACF3UF_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670618.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12249..12629)
                     /locus_tag="ACF3UF_000463"
     CDS             complement(12249..12629)
                     /locus_tag="ACF3UF_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3670619.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            12959..13708
                     /gene="pnuC"
                     /locus_tag="ACF3UF_000464"
     CDS             12959..13708
                     /gene="pnuC"
                     /locus_tag="ACF3UF_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFD3670620.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(13892..15169)
                     /locus_tag="ACF3UF_000465"
     CDS             complement(13892..15169)
                     /locus_tag="ACF3UF_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670621.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15248..15892)
                     /gene="pcp"
                     /locus_tag="ACF3UF_000466"
     CDS             complement(15248..15892)
                     /gene="pcp"
                     /locus_tag="ACF3UF_000466"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFD3670622.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16091..17035)
                     /locus_tag="ACF3UF_000467"
     CDS             complement(16091..17035)
                     /locus_tag="ACF3UF_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFD3670623.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17037..17723)
                     /locus_tag="ACF3UF_000468"
     CDS             complement(17037..17723)
                     /locus_tag="ACF3UF_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFD3670624.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18197..18517
                     /locus_tag="ACF3UF_000469"
     CDS             18197..18517
                     /locus_tag="ACF3UF_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFD3670625.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            18671..19576
                     /locus_tag="ACF3UF_000470"
     CDS             18671..19576
                     /locus_tag="ACF3UF_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670626.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19573..20346
                     /locus_tag="ACF3UF_000471"
     CDS             19573..20346
                     /locus_tag="ACF3UF_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFD3670627.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20527..21951)
                     /locus_tag="ACF3UF_000472"
     CDS             complement(20527..21951)
                     /locus_tag="ACF3UF_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFD3670628.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22162..22608
                     /gene="nrdI"
                     /locus_tag="ACF3UF_000473"
     CDS             22162..22608
                     /gene="nrdI"
                     /locus_tag="ACF3UF_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFD3670629.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(22673..24655)
                     /locus_tag="ACF3UF_000474"
     CDS             complement(22673..24655)
                     /locus_tag="ACF3UF_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFD3670630.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(24669..25565)
                     /gene="murQ"
                     /locus_tag="ACF3UF_000475"
     CDS             complement(24669..25565)
                     /gene="murQ"
                     /locus_tag="ACF3UF_000475"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFD3670631.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(25568..26629)
                     /locus_tag="ACF3UF_000476"
     CDS             complement(25568..26629)
                     /locus_tag="ACF3UF_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFD3670632.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(26840..27367)
                     /locus_tag="ACF3UF_000477"
     CDS             complement(26840..27367)
                     /locus_tag="ACF3UF_000477"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3670633.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(27434..28936)
                     /gene="eat(A)"
                     /locus_tag="ACF3UF_000478"
     CDS             complement(27434..28936)
                     /gene="eat(A)"
                     /locus_tag="ACF3UF_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFD3670634.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(29194..30315)
                     /locus_tag="ACF3UF_000479"
     CDS             complement(29194..30315)
                     /locus_tag="ACF3UF_000479"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFD3670635.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            30441..31382
                     /locus_tag="ACF3UF_000480"
     CDS             30441..31382
                     /locus_tag="ACF3UF_000480"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFD3670636.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(31532..32428)
                     /locus_tag="ACF3UF_000481"
     CDS             complement(31532..32428)
                     /locus_tag="ACF3UF_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFD3670637.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            32697..34037
                     /locus_tag="ACF3UF_000482"
     CDS             32697..34037
                     /locus_tag="ACF3UF_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3670638.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            34255..34698
                     /locus_tag="ACF3UF_000483"
     CDS             34255..34698
                     /locus_tag="ACF3UF_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFD3670639.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(35202..36620)
                     /gene="nhaC"
                     /locus_tag="ACF3UF_000484"
     CDS             complement(35202..36620)
                     /gene="nhaC"
                     /locus_tag="ACF3UF_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFD3670640.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(37023..38246)
                     /locus_tag="ACF3UF_000485"
     CDS             complement(37023..38246)
                     /locus_tag="ACF3UF_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFD3670641.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(38277..39116)
                     /locus_tag="ACF3UF_000486"
     CDS             complement(38277..39116)
                     /locus_tag="ACF3UF_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD3670642.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(39133..39813)
                     /locus_tag="ACF3UF_000487"
     CDS             complement(39133..39813)
                     /locus_tag="ACF3UF_000487"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFD3670643.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(39815..40888)
                     /locus_tag="ACF3UF_000488"
     CDS             complement(39815..40888)
                     /locus_tag="ACF3UF_000488"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFD3670644.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(40944..41182)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(41225..41458)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(41535..42206)
                     /locus_tag="ACF3UF_000489"
     CDS             complement(41535..42206)
                     /locus_tag="ACF3UF_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3670645.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(42293..44941)
                     /gene="mgtA"
                     /locus_tag="ACF3UF_000490"
     CDS             complement(42293..44941)
                     /gene="mgtA"
                     /locus_tag="ACF3UF_000490"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFD3670646.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(45283..45457)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            45630..46067
                     /gene="ndk"
                     /locus_tag="ACF3UF_000491"
     CDS             45630..46067
                     /gene="ndk"
                     /locus_tag="ACF3UF_000491"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFD3670647.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(46089..46955)
                     /locus_tag="ACF3UF_000492"
     CDS             complement(46089..46955)
                     /locus_tag="ACF3UF_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3670648.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(47115..49208)
                     /locus_tag="ACF3UF_000493"
     CDS             complement(47115..49208)
                     /locus_tag="ACF3UF_000493"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD3670649.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(49957..50580)
                     /locus_tag="ACF3UF_000494"
     CDS             complement(49957..50580)
                     /locus_tag="ACF3UF_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670650.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHVGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(50739..52136)
                     /locus_tag="ACF3UF_000495"
     CDS             complement(50739..52136)
                     /locus_tag="ACF3UF_000495"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3670651.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(52168..53139)
                     /locus_tag="ACF3UF_000496"
     CDS             complement(52168..53139)
                     /locus_tag="ACF3UF_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3670652.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            53513..53938
                     /locus_tag="ACF3UF_000497"
     CDS             53513..53938
                     /locus_tag="ACF3UF_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670653.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(54426..55127)
                     /locus_tag="ACF3UF_000498"
     CDS             complement(54426..55127)
                     /locus_tag="ACF3UF_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFD3670654.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(55143..55583)
                     /locus_tag="ACF3UF_000499"
     CDS             complement(55143..55583)
                     /locus_tag="ACF3UF_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFD3670655.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(55583..56158)
                     /locus_tag="ACF3UF_000500"
     CDS             complement(55583..56158)
                     /locus_tag="ACF3UF_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFD3670656.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            56399..56608
                     /locus_tag="ACF3UF_000501"
     CDS             56399..56608
                     /locus_tag="ACF3UF_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFD3670657.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(57006..57518)
                     /locus_tag="ACF3UF_000502"
                     /pseudo
     CDS             complement(57006..57518)
                     /locus_tag="ACF3UF_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(57644..58345)
                     /locus_tag="ACF3UF_000503"
     CDS             complement(57644..58345)
                     /locus_tag="ACF3UF_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3670658.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(58453..59895)
                     /locus_tag="ACF3UF_000504"
     CDS             complement(58453..59895)
                     /locus_tag="ACF3UF_000504"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3670659.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            complement(59909..61774)
                     /locus_tag="ACF3UF_000505"
     CDS             complement(59909..61774)
                     /locus_tag="ACF3UF_000505"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFD3670660.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(61895..62746)
                     /gene="licT"
                     /locus_tag="ACF3UF_000506"
     CDS             complement(61895..62746)
                     /gene="licT"
                     /locus_tag="ACF3UF_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFD3670661.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(63056..63769)
                     /locus_tag="ACF3UF_000507"
     CDS             complement(63056..63769)
                     /locus_tag="ACF3UF_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFD3670662.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(63837..64163)
                     /locus_tag="ACF3UF_000508"
     CDS             complement(63837..64163)
                     /locus_tag="ACF3UF_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFD3670663.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(64286..64513)
                     /locus_tag="ACF3UF_000509"
     CDS             complement(64286..64513)
                     /locus_tag="ACF3UF_000509"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFD3670664.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(64835..66088)
                     /locus_tag="ACF3UF_000510"
     CDS             complement(64835..66088)
                     /locus_tag="ACF3UF_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD3670665.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLIGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            66149..>66578
                     /locus_tag="ACF3UF_000511"
     CDS             66149..>66578
                     /locus_tag="ACF3UF_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3670666.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGS"
BASE COUNT        19302 a        13855 c        11476 g        21945 t
ORIGIN      
        1 cctttcactt gagaaataat gtaatcggta taagcagatc cttgcgaaaa atcaatacag
       61 acatgaatcg gtgcttcaaa atatgatacc ggacaaatac cgaccaataa aaagagataa
      121 tcataaaata agcgaatcat gaaacgttca tcttttccca agaaatagcg tttattctct
      181 tgtatgacct tttggattgc tgtactgaat attggatacg tctcgaagaa aaactgtagc
      241 tgctttttag acgtaaagct agtcatctca aagtcgaata tccaattttt tcgattgaca
      301 tgcatcatac ccatacgaag ttcttttcgt atatatagtc tttcttcttc agagatttca
      361 atcgaaaatg gtaattgatc aatcaattcc actgacattt tttgactaat catgtggata
      421 tcatgaaaat gagcttccgc aagtccaaat gcgccatcta attcaaattc ttcttccgtg
      481 atcaaaaaca acatgatata agaaatctca tcaatgatct gctctttagg gatatgaaga
      541 aaagaaatat gtgataaatc cttgatgatc ttcattcctt ctgagctctt aaagtattca
      601 tctgaaaaga aacgttttcc gattggttga ttcccatagg ccctcaacaa actaatagtg
      661 gttagcaaat tgaatttgat tcgttttgtt gcagacagtt ttaaattgaa cagatattca
      721 aaatattgca cgatactctt tgcttcattc atgacgcttt ctctaaatgg catagaaaaa
      781 ccattaaaga ccccgaaata taccccaaat aatacgttcc gtatgtttat ttcttcccca
      841 actaatatgt ttttctttaa ctttatttga tgctgttcaa gaaaagagac taattctctt
      901 ctttttacat aggctcttga tatgcttaaa aaatgattct ctgcaaattt ttcgatcgtt
      961 acttttgaat ccacgatctc cgttaacagt cgagcaattt ttgatcgttg aaagtagatt
     1021 cttcttaaat ttttgatatc cgtcaaattc agacgttcga catggatctc tgcttcttct
     1081 gaaatttgga tctctggctt tgttttgaat tcagtaaatt ctttatttaa ttctatgata
     1141 taatttcttg ttttaaattt agacaaacct aatgtttcat ataacttagg cagcactaca
     1201 taattctttt tctcaaattc taaatatcta gctagcagca gtttttctct atcttcctct
     1261 tctataaggt aatccaactt catatcctac acctcaaaaa atgcctcata ccaattactt
     1321 gatatgcaga tgaaagttca tcttttcacc tatactgatt ttatgatgga ttatgcttgt
     1381 tttttcatca gttattctca ttttttatct tttttttgag aatattgcaa aaaatggaaa
     1441 aatttatgag gaaatattct atattttttg ttttattgtg ttaaaatgta caagatttgc
     1501 gccatttgcg taaacaacca caaaaaagag caggacggcc accgtcctgc tcttttactt
     1561 attttaagtt ccattactta ttaattggct aaacttctgc ttgtttctga tattgcttgt
     1621 ttttctccaa tgatccgcac ttctgtttct aaagacacat caaatttttc tttgattact
     1681 tcttggatgt gcgcaatcaa ttcaatataa tctgtcgctg tcgcatgatc gatattgacg
     1741 atgaatccag catgtttttc agagacttgt gcaccgcccc atttcaggcc ttgcaatcct
     1801 gcttgttgga tcagctgacc tgtatagtgt cctactgggc gcttaaagac acttccgcat
     1861 gaagggtatt ctaatggctg ttttgattga cgcaattcgg tcaactcatc cattcttgct
     1921 ttgattgctt cataatcccc tgtttgcaaa ctgaatcgag cttccaatac gatagcacgt
     1981 aattcttgga ctttactgtg acgataagaa aataccattt cgtcttttgt caaagttttc
     2041 aatgttccat cttcaagcaa aagatccact tcagcaaaaa catctttgat ctctccgcca
     2101 tacgcacctg cattcatata aaccgctcca ccgacacttc ccgggatgcc gcaagcaaat
     2161 tcaaatccag tcaatgattc tgccaaagct gcataagtcg tatcaatcag tgaggcacct
     2221 gcttccgcaa tgaccatcgt tcctttgaca tgaatctgtt tcatttcagt cagcatgatg
     2281 actacaccgc gaatcccgcc atcttgaacg atcagattgc ttgcatttcc taataccatc
     2341 caaggtatat catggattcg gcaataatcg atgatttgct ttacttcttc ttgttttttc
     2401 gggaatgcaa ggacatcagc tggtccacct gttttcgtaa acgtatagtt catcaatggt
     2461 tcatcaaaca atatagtaat cgtggctaag ctttcaacta tttcttcttt attcactgag
     2521 gattttcctt tcttttctca aacgtcctca ttattctatc acgcttaata caatcttgcc
     2581 agtcttgttc aaagttgatg acggtagtga tctttaagca cttcctcaca taattcatga
     2641 cttcttacaa cttctttttg tttaagcaat tctgtttccg atttacctaa acggatctga
     2701 gaaaagaagg cctctaccat tggctcaaac ccgcgtttga ctagcgtgtt tgtccagtcg
     2761 ccaaattctt tcactttttt tccatcagca tcttgaatga caagctgggt cagatcgttt
     2821 acttcataag taccattttt acttgttact tgatattttt ctatattagc gccacttgct
     2881 aaatccatcg ttaaaatagc cgtttgattt tgtgtttcta attgtaaaat ggcatattcc
     2941 aaaaattcct ttgtttctct tatctggtat tttgttctca aaatgggttc atctaataaa
     3001 tacacagctg tatcaataag atgtaaaaac aaatcataaa ggacgaactc tgtcgtttct
     3061 tttgccgcta ttcgattttt ttgcaggtgg atcaaccgct tatctgggat acgtttcaat
     3121 tcttctacca taggagcaaa gcgccggttg aaaccgatca tcaaaattat ttggttctta
     3181 tcagctaatt cttgcaattc acgaacttca tttagatgga cactcagtgg tttgtcaata
     3241 taaacatgga taccattttc tagacatttt ttggctaatt cataatgtac ttttgttgct
     3301 gcgtggatca tacatgcttc gattttttct tctaaaagct catcgatcgt ttcatataga
     3361 tgttggaacc cgtactcttt ttgaattctt tcttttgttt ctttatttct tgttgcaaaa
     3421 taaaaatcaa gtgttccttg ttttttcgca taagttggta aatatgcttt ttctgcgata
     3481 ttccctacac cgattacacc aatcttcatc tactttcctc ctggatcatt tagttacttt
     3541 catcttacac cattttttac taaaatgagg tacaatagta tcgcaaaggt aaggaaatta
     3601 attcgaagga gtgtgctttt attgaaattt atctcttgga acgtaaacgg gcttcgtgcc
     3661 atcgtaaata aaaatttttt agaagttttt catgagttag acgccgattt tttctgtctg
     3721 caggaaacga aactccaagc aggacaaatt gatttagatc ttccaggtta ttatcaatat
     3781 tggaattacg cggaacgaaa aggctattcc ggcacagcga tttttgctaa aaaaccagca
     3841 ttgaatgcca cttacggaat gggtatcgat atccatgata cagaaggccg tctgattact
     3901 ttggaatatt ccgatttctt tcttgtaacc tgttacacgc caaattctca aagcgaatta
     3961 aaacgtttag attaccgatt agaatgggaa gaagcctttt ataattattt ggaaaatcta
     4021 aaaaaacaaa aaccagtcat cgtgtgtggg gatctaaatg tcgctcatca aaagattgat
     4081 ttgaaaaact ggaaaacgaa tcaaaaaaat gctggattca ctccagaaga aagagcggct
     4141 ctttctcgac tgttggataa cgggtttatc gatacattcc gttattttta tccaacccag
     4201 gaaggtgtct actcttggtg gaactaccga ttcaattcaa ggaaaaacaa tgctggttgg
     4261 cggatcgatt actttttgac gagcaaagat ttagagccag gactagctga tgcaaagatc
     4321 catacggaca ttatgggcag tgatcattgt ccagtagaat tagatttgaa ataaagaggt
     4381 tgtgaaaaag tcgtttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
     4441 ttttgcataa atttggcata ataccgagaa actggctttt gaacactgtt tatcgagaga
     4501 ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat agttcctcat
     4561 atttttcgtt tggttgggct tattaccgca gatacaagct tttgaacacc gtttattaag
     4621 aggttgtgaa aaagctgcac tgcatcaagt aataagaaca gccaaacaaa aatagttcct
     4681 catatttttc gtttggttgg gcttattacc gcagatgcaa gcttttgaac accgtttatt
     4741 aagaggttgt gaaaaagctg cactgcatca agtaataaga acagccaaac aaaaatagtt
     4801 cctcatattt ttcgtttggt tggacttatt accgcagatg caagcttttg aacaccgttt
     4861 attgagaagt tgtgaaatca gcgtcctgac ctgagtatta gagaaacaaa tggcaaaata
     4921 gttcctcata ttttgctatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt
     4981 tagtggagaa gttgtgaaaa agtcgcctac tttcgagtcg taagaaattt ttttgaaaat
     5041 ggttcctcac aactttgcat aaatttgact taataccgag aagtcatgat ccccatctaa
     5101 ctccaaatca caaggaatga gttcaaaaac tagcttttct caacaaatat tacataaaaa
     5161 attctatgtt ttttgttaaa tttatttgct tttttcaaaa gtatgttaca gtaatttccc
     5221 aaggaggttt tacagaaatg aattttgttg ccatggattt tgaaactgcc aatcatcagc
     5281 cttatagtgc ttgttctctt gcgctagtca tggtaaaaaa tagccagatc gttgatgaat
     5341 tctatacatt gatacagcct gagactcctt ttttctggcg aaatgtccaa attcacggaa
     5401 tccatcaaga agacgtacgc aatgcgccga aattcccaga agtctggcaa actatccaac
     5461 catattttca aaaaaatcgt ttagtcgttg cacataatgc tgcttttgat acaaaggtct
     5521 tagcgggatg cttagattat tatcatcttg aacagcctaa ttatctttct ttatgtacag
     5581 tgaaaagtag ccgtcgcctg tttcctgaat ttccaaatca tcgattgaac actgtgtgcg
     5641 aaaatttgaa catccaatta gatcatcacc atgatgcatt ggaagatagt cgtgcatgtg
     5701 cggaaatcct gctttatcaa gaaaaaaaat tcgggacaga tccattgaaa aaacttgtga
     5761 ctataaagta aaagaatact tatgaaacac acaaagaggt cgtgagcctg ccgtttcact
     5821 ccgagtcaca aggagcaatt tcaaaaaata gcttctcatg tttattaaat attgtgactg
     5881 gtgaccgagg agctggcagg agaacaccgt ttattggaga ggttgtgaaa aagctgttct
     5941 gcatcaagta ataagaacag ccaaacaaaa atagcttctc atatttttca tttggttgga
     6001 cttattaccg cagatgcaag cttttggaca ccgtttacca agaggttgtg aaatcagcgt
     6061 tttgacctga gtattagaga aacaaacggc aaaatagttc ctcatatttt gccgtttttt
     6121 gagctaatac cgaaggtcag ctgattgaac accgtttatt caaaaaaaat ggactgcgac
     6181 acgacttttg tcacagtccc ttcgtgtgtt tttctgcctt ctcaaaagga tgacagtttc
     6241 tcactctttt cctatttctt ctattcaatc aaataactca ttttatatac atctaaaaat
     6301 tcacctagat ctgttcttgc ccctctaggc atgaccgctt cgatttggaa gcccattttt
     6361 cggtaaaggt gtacggctct ttcattacga acttgaacgt caagctccaa tcgaaaaagt
     6421 acacccattt ccttcgccca actgatgatt tcttctagca taagagtgcc tagtcccatt
     6481 ccccaatatt cctgcagaat actgataccg acttctccca cgtgagacaa acgaaattga
     6541 ctgtctgcct tgacagatgc tgttccaata atcgtccctt catagattgc aagcagcaat
     6601 aaattattat tgctttcgta tatataatcc aactcttctt ctaaggtttc tggtggtaac
     6661 aggagttctg cttcatccaa aactaaaaat tctgtctcct tattaacttg tcccatcatc
     6721 aaaagaatgt cttttgcatc tcctggcact gcttcccgca agatgatccc aacttcttca
     6781 ctcatgattt tcagcccatt tttctagaat tcgctgtttg aaggtttcac tttgctcccc
     6841 gtatgagatt agtttcacat accgcttttc taaatctgta tcactttttt ctaaaatcag
     6901 ttccaaataa tcctccggca gtgcttcttc taatagattt ccccattcaa caacggaaag
     6961 cccatcacct tcaaaatatt catctaaccc taaatctgct ccgctagctg ctacccgata
     7021 aatatccata tgatacaacg gaatccgacc ttgactatat tctctaataa tcgtgtatgt
     7081 cggacttttg atcatttgcg ttatccctaa tccttgggca attcctttcg tcaacgttgt
     7141 tttacccgca cctagatcac cagtcaatat cagattgtca cctggcattg cggaatgacc
     7201 aattgcctct gcgaattgtt ctgtcattgt taatcctgat agttcgatca tttttcatct
     7261 tctcccgctc ttctttcttt ttgccagtat atcgcgtaat gaagtttttt taaagaaaaa
     7321 atgaactagt caagaacagc agctgctgtt tttggctagt tcgcgtgtat ttgttaatca
     7381 atcaatgttt gtgctgctgt gataatcgat aatttatata catcttcttc atttgctcca
     7441 cgagacaaat cagaaaccgg tttgttcaag ccttgtagaa ttggtccgat tgcttcaaag
     7501 ttaccgaaac gctgagcaat tttatagccg atatttcctg actgcaattc tggaaataca
     7561 aagactgttg cttgaccagc tacttctgaa tctggcgctt tcagttgtgc aactgaagga
     7621 acataagaag catcaaattg caattcgccg tcgatcatgt attgtggcgc tagtttttta
     7681 gcgattttag ttgcttcaac tactttgtct acttctggcg atttcgctga gccttttgtc
     7741 gagaagctca tcattgctac ttttggttcg atatcgaaca attctgctgt ttttgcagaa
     7801 tctacggcga tttcagccaa ttcttgcgca gttggattca cgttgatcgc acaatccgaa
     7861 aagacatatt tttcttgatc tcttccacgt accatgatca tcgctccgct tgtccgactg
     7921 atgccaggct ttgttttgat gatctgaagt gctgggcgaa cagtgtcgcc agtcgaatgg
     7981 atcgctccag agaccattcc gtctgcaatc cccatatacg taagcatcgt accaaagtaa
     8041 ttcacatctt ttaaaatctt ttctgcttgt tctttggatg cctttccatt tctacgttca
     8101 acaaaagtat ccaccatttc atcccactta tcgtaattat cagggctgat gatcgtaaag
     8161 ctagatgttt tgattcctct ggcatgcgct gcatttctta tttcttcttc gttccctact
     8221 aaaatgggtt ccacaagttc ttctgctttc aaccgggcag ctgcgcctaa aatacgagca
     8281 tcagtagctt ccgggaaaac gattttgatc ccacggcgaa caattttaaa tcttaaacta
     8341 tcaaacaatt ccacaagatg acctccagac gtttttatat gtattatcat acactattcc
     8401 agaaaaaaag aacagtttat tttatctgta tcagtcaaaa atgctggaaa aattaagttt
     8461 ttcacataca aagcgaactg cactataaca ggaaagcgct gttttattac actgtttcag
     8521 gcagttgcca atcaatcggt tcttctccta acgcaaggag cgcatcattc gttttcgaga
     8581 agggtttgga accaaaaaag ccacgacttg cagataacgg actgggatgt ggagatgtta
     8641 tgatgatatg gcgactctta tcgatcattt tgattttttc ttgtgccggt tttccccaca
     8701 agataaacac gattggtttt tcccgttcat ttaatttttc aatgatcgtg tctgttaatc
     8761 tttcccaacc tttcccgcga tgagaatacg cttgcccttc ccgaacggta agaacggtgt
     8821 tgagtaaaag gactccctgt ttagcccatg acactagatt tccatgttga acaggtgcga
     8881 ttccaagatc atcataaagc tctttataga tatttcttaa cgatggcggg atctttacgc
     8941 caggttgcac agaaaaagat aagccatgag cttgattttc tccatgataa ggatcttgtc
     9001 ctaaaatcac cactttaact tcttcataag gagtcaattc caatgcttca tagatatgat
     9061 acatatctgg atggatcttt tgggacgcat attctttttt taaaaattct cttagatgca
     9121 gataataatc ttttgaaaat tctgaggaca aaacttcttg ccaactgtta tgaatgattt
     9181 ctttcaaaaa ctccacctcc taataaaaag aataactcac attttcttca atcacaaggg
     9241 acaatcttca ccctcagcac ttgattaata tggtaaacta ggaacaagaa gcagaaagga
     9301 acgataatca ttatgatcaa attaattgca tcagatatgg acggcacatt attagatgcc
     9361 catatgagtg tttctcctga aaatgccgag gcgatacgtt ttgcaaatga tgccggtgtt
     9421 gagttcatgg tcgctactgg tcgaaactat caagaagctc gcgcagcttt agatgaggta
     9481 ggaatcgatt gtgcgatgat cactttgaac ggggcacagg tatttgataa agaaggaaat
     9541 tcattgttta ccgtgtcgat tccaaataat caagcaatct ctgttttaga tattctagat
     9601 gctaacggta tttactatga agtagcaacc aacgatggtc tttattctga aaatcaagcg
     9661 aaacgaattg aaagttttgc ttccatggtg gctacccatt tacctcacct tacgtataaa
     9721 atggcgattg ccatggcctc agctaagctg gagttattgc acatcacata cgtggacagt
     9781 attcgtgcta ttttggaaga aaagaatctg gaagttttaa aaattatttg ttttcataca
     9841 gaagggccag ctgtattagg tccagttgga aagcagattt ctcttttagg cgatctagcc
     9901 gttacttcct ctggtcaaaa caatatcgaa gtgaaccata aaaacgctca aaaaggaatt
     9961 gctgttgccc atgtcgctca cgagcgtggg atttctttag aagaagtcat gacgattggc
    10021 gataacttca atgatgtcag catgctgcaa gtagcaggag tcagtttcgc aatgggaaat
    10081 gcagaaatcg aagtaaaaga ttatgccaaa tatacaacgg acacaaacct tgaatctggc
    10141 gtaggaaaag ccatattgcg cgcgattgca gaagacttgt agttttatct agaaaagagg
    10201 gatatagatg tcagaatttt tcattcagga aaagcagctt ggacgtgcaa ctcggacaat
    10261 tgtcaaaaac gaaaaaggac attccctgtt tttgatggtt ggtcgctggg gaacaaaggg
    10321 cgatgcattg tctctttatg ccatgaatgg cgatctcgtt gctcacatca agcagataag
    10381 cctgacattc ggtacgcgtt ttgagctgta taaagagttc gaaaaggtgg gaaccatgca
    10441 gaaaatattc aattggcccg gtgactttta ttatattcgt agacttcact ggacagtcca
    10501 aggtgatatc tataatcatc aatatcaaat ccatcatttc aatcagcaaa tcatgaaaat
    10561 ggataaagca acactttttt caggagatta ctatgtattg gatgtctcaa atgatgaaga
    10621 tgctccagtt tgtatttgta ttgctgcggt tttagattac tggctctacc gtaaagacaa
    10681 aagtcgcgat aagcctgttt cttaccgact taacttaagt taaaaagatg tacctgaaat
    10741 gcggaaatac gcatttcagg tacatctttt tagatattct tttgcatatg atcataaaga
    10801 tgaccactga tcatccgctg accgacaact ttgaagtcat ggcgttcgta taatttttta
    10861 gcctttggat ttttttcatc cacacttaga ccgatgacgg agcgattagc tttcttcgcc
    10921 aatttaggta atgcttctaa taatcgcgaa ccgatgcctt gtcctctaaa atcttctgat
    10981 acactgatag agtccaaata ccattcgttg ggaaacgttt ctttatcaat gaacaaacgt
    11041 gtagacgcat ctagctgata tttctctaag ataggtacca gtggctgatc gatgattgat
    11101 tcttcttcat ctgtataacc gtaagcaact cctgcaactt taccgtctat ttcttctacg
    11161 atacctcgtg aataactgta acgataattt ggatcagtga ttgcttcttc taaaatctct
    11221 aaagtctttt gttcccctgt ctgcttcaaa aatggcagtt ccatatcttt tagaatcact
    11281 aagatcaatg gggcgatttc tggagcatct tcttttctcg caaaacgaat catagtttcc
    11341 tctccttttc tccattctaa catgcagaaa aagaaatcgc aaaatcgtta ttttaaaaaa
    11401 tcttcaatct tttcagtaat gaaataacca tgagtaacga ttcttgccgc ttcagttcgg
    11461 caataagggc agacgactgg catttcttta tcattatgtt cgactacatt attgacttct
    11521 tcgtatgcaa atttttttcc gcaattaggg catttcattt tttccatgtt atctcaactt
    11581 cctttcatct ttactctctt agcttactct tatattgtaa aaaagagaag caatatcctt
    11641 cttctatgca gatatccata cctgacggtc ctgttctcca tctattaatc ggactttata
    11701 ataaggacgt tcatctttga ctagaagtgt ccactctttc acttttgctt ttttcccgta
    11761 gtagctgact gcttccttca tcgctgcttg cggttgtttg aactcttccg ttttttctat
    11821 atcaaaaaga tgttctgcgg ccttttccgt gtcatttcgt acggttgttt tcccagtgga
    11881 tggattgact gctatgactt gtccttcaca aaaaaactgg tattcatatg ttgcattcgt
    11941 aggattctcc aaatcttttt caactgcaaa atgaatagca gatatgttat gttcttttgt
    12001 ttcgtttttt acgattgctg ctgctttttt caatgagatc cgatattcct ggtcactaat
    12061 atcatccatg tgaaaagcgg cattgagcag tcccgtcata ccggtaatcc ctattacgat
    12121 gagggcagca acaccaaaca tcattttttt cattcttcat tctcctgttt ctttttttta
    12181 aagaatatca agaaatgaac gaatgaaaaa tcgaatgaaa cgaaaaaaaa gtgacaattt
    12241 tgttatcttt attcgtgcag ttctaatggc aatccgtctg gatcaaagaa aaacgtcatt
    12301 ttttttcctg taaaggtatc ttctctaatc ggttctgatt cgatccctaa ggactgcaat
    12361 tctgcaattg tttcttcaat atcgtctact ttgaaagcaa gatgacgcaa gccacaagct
    12421 tctggatagt ttggtcgttg tggcgcatta gcaattccaa aaatctccaa ttcagcactt
    12481 cctagtttca gatctaattt atagtcatct cgttctttgc ggtaattttc tctgattact
    12541 tcaaatccta atttattaac ataaaaatca cgtgatttct gataatctga aacaatgatg
    12601 gctatatgat ggatcgttgt aaggttcata tgagcactcc tattcttcgt ttaagctcgg
    12661 atctatatta atctccagtt ccattgtaaa tgtgtcagat tgaaaaaaat agctgttttt
    12721 cctttttata agaaaaaagg caaaaaaaac agaaagtagg tcctccaaga cactcttcct
    12781 gttcccaata taataaatga aagtaagaaa ttatattttc aagaaaacaa acagaaaatt
    12841 atcataacac aaattattta taattgaaag actagttttt tttcaagaaa agcatacaat
    12901 agattgtgtt agtaaataca gaacacacta catttagtgt cttaaggagt cctcatacat
    12961 gaagtcatat tttcagtttt tagctcatca gctaaaaggc tggccgcaac aaaattatta
    13021 tcttttcttt ttcagtcttg gctgccaggt catgactctt gtcaatagtc ccatcacttg
    13081 gctgtccgtt attacattta tcggtaccac gcttggtgta ttgtgtattt tatccatcaa
    13141 tgcggcaaaa tcagtcaacg gtattttagg tattttgtct gcgatttgtt ttattatcgt
    13201 tgggttttca gcaaagaact atttaagtat cggtgaacag attgcttata tgatcacatt
    13261 ggatatcccc gtattgttaa gtaaagaatg gaatcataat atggcttcaa aaatccgaaa
    13321 attcactgga aaaagctggt ttatcgcaat catcagtact ttccttgtct atcttgtttc
    13381 aggattcctg attggtcgtt atacagatga tcctcggccg tgggtagatg ccattgcttt
    13441 ttctattagc ttgactgctg gtatcatcag tttcttgcgt tacaacaacc aatattactg
    13501 gtggttagct tcagggcttg ctcaaatggt cctttggtat atttcattta cgcatggatc
    13561 tgcaagtttg gcgatgttcg tgaacagctc tgtttacttg ctgaatgatg tccttgcatt
    13621 taccgtttca ccttggtata accaaaaaga acgtgaacgt atgcaaaaaa tggaagaaga
    13681 atactacaac gcacaacaac acgcataaaa aaactgagcg tgggacaaaa gtaaagaaca
    13741 cttttgtctc acgctctaaa cacgtataaa cggcggaatc agaagcaact ccttcggaaa
    13801 taagctgaaa ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg
    13861 agttaaacgc ttctgtccca gcctctattt tttatagtaa ttccttcaga tactttcttg
    13921 cctcatcatt gaaacgcagt gattcttcta acttctgata atattccaac gcttgtttct
    13981 gagcttcagt aaaacgataa tgttttcctt tccatttgtc gattgtctct tgcacatttc
    14041 cagattggat atctttcact actagttgcc atttttcttt tgagactgta cggtctttct
    14101 tatcagcaga ttgtatagct tctcgttctt tacgcaatac ttttaaaaaa ccatttctga
    14161 ctatccgagg aatgctgtcg aagaaccctt ctgtaaaacc atagcgacaa tattgcttcc
    14221 aaataaatag atagattttt ggttggatga atcgttggtt tttcgcaaaa tattccatct
    14281 gagcagtgac ttctggtgtt cgttgacgtt ttgtctttct caacacggaa ataaatgttt
    14341 caaaataagc attaggatgt actggcactt cttcatatac gatggattgc caatctttac
    14401 gtaaaaatgc gcgatagttg atcaagaatt cttctacatc ctttactaat tcttctgcaa
    14461 agtcgtcaaa tagttctttt tttatctgtc gcttttttga ctgcccattg atgtgttcac
    14521 ttattttctt gatttcattt tccaatgctt gataatccgc tatgtaaatc ggcatttcta
    14581 cttggcgaaa ttctgcgagc cgctgagcta attttatatc cggtaaatat ggctgtttca
    14641 tccgacgatt ttggtacaag acaaaacagt atttttgcca tagtccttca ggaaaatcga
    14701 tattcttctg cttaagccat aataattcgt ctaaggccag atcaactttt gtcattccct
    14761 gatggatcga agctgccact gtcggagaga catgcaggtg atcggcaaag tggttgatgc
    14821 ctagttttag gatctttccg gtttttggcg atttaacgat gtattgcact tttaattctc
    14881 taccacactc acaatacaat ttttgctggc ttcgttttgt tcgaaaaaac ggattgatct
    14941 tgaagtcaga aaacacccaa tctgttgcag ctaaataatg ttcttccata aaacgagagc
    15001 tgattagata tcggcggtgc ttatcgacta gttcccgctg ttttttcgtt aattttgcat
    15061 agatctccca acgttgactg cttgtgtatt gtttagaaat tttgatggga tagcttttgc
    15121 tgatttcttt tggaaaccat tcttcaaaga cggattgcca ttcttccacg gctgtttctt
    15181 tcctttctaa ttacaaaaag ctggctacta acataacgtt agcaaccagc cagtgtttct
    15241 tgctaaatta gtgagttgtt ccggcatttc cggaaatatc ttctttattt tctactgctg
    15301 cttcaactgc ataagtcaaa gaagaagcaa tgtcttctaa agacatagaa ggcgtaccca
    15361 ctggacgatc gatcacttga tcgggtgaga atggcacgtg gatgaaccca cctcgaattg
    15421 ccgggaattg tgtttcgatc aaatgaagca aacgatacat gatatcattg cagacaaatg
    15481 ttcctgctgt ataagagatg tacgctggta gaccatgatc ttgtacattt tttgtcattg
    15541 ctttgattgg caatgaggta aagtaagcgg ctggaccgtt ttcttctaaa gccgtatcga
    15601 atggctgatt tccttcatta tcagggattc ttgcttctgc tagattgatt gcgacacgtt
    15661 cgaacgagac tgctgaccgc ccacctgctt gtccgacaca gatcacgaca tctggttggt
    15721 gctgttggat ggcttctttg actacttgac tgcttttttc gaatacggtc ggtacttcca
    15781 ctttgatgat ttcagcaccg ctgatttcat ctggcatttt ttttactgct tcataggctg
    15841 gattcacttt gtccccacca aatggatcaa aacctgttac tagtactttc atctgttgtt
    15901 cctccgtccg attgatttaa catatggtta tcttttatca taccattttc cttgaacagc
    15961 gtaaataaag gaaacaatag tttaaataac ataacagatc aaacttaata tattcttata
    16021 aaaaaatagt gttccactac aatgttagaa gaggttgcga caattattct gtcacaaccc
    16081 ctctcttcta ttatttaaat agaatcatat aagcaatttg gaaaactagc ataaataacg
    16141 caataaacaa ctggtttttg atcactccgt atttgtcttt catctccagc atcgctacag
    16201 gcacgatatt gaagttagca gccatcggtg tcagcagggt cccacaaaaa ccgcaagtca
    16261 atgcaaccat tcctattaac gctggattcg ctccatgact aaatacgaat ggtgcaccga
    16321 tcccaaccgt catcacggtg atggccgcaa atgcattccc catgattacc gtaaatatca
    16381 ccatgccaag agcgtaaatg atgatgccga tgttcacatt tccttctgga acgatcgtac
    16441 ctactgcatt ggaaatcact gtcccaactc cagcgcttgt aaataccgca cctagagaag
    16501 ctaaaagcat tggcaacatg cttaacggcc ctactgtgcc cagcatatct gctgcatcat
    16561 ctaaaaatgt acttggtcga ttatctcgag aaaagaacat caagattagc atggctgcaa
    16621 aaacaccgac gcccacgccg actaaagcac ctaaattggt aaatagagca aacaagatcg
    16681 caaagacacc gatactcaaa gctggaataa aaattttcat tcctagtttg tctgacattt
    16741 tttccatata ttcttttgat ggaagccggc tttctccttt gctgactttc ttagcaattg
    16801 ctggtatggt catcgcaaag atcaagccac cgttcacgat tgccggaagc catcttcctc
    16861 ctgcaataac tacccctaag accgtccaga aaaaggctga cccataacga tgaggattgg
    16921 ttttatctgt taaatttctt actccagtgt aaatcaatac gagtcccatc acgatataaa
    16981 ggatctccag taatttatcg cctaataaaa tatcaggatt tgtaaaaaag tccatcttat
    17041 tgcccctttc ctggataata tttcttcgct aatttctttt ctttaagata gaagtagaca
    17101 cttgccacaa ctaaagccgt gatagccact ggaacttcca ctaaagcaag ctgtcccaat
    17161 gttacgtcat atcctagatc tttcagtgtt gattggacta gcaacgcccc tgctcctccg
    17221 atgaatagta cttggccaaa gaaccagcag acattttcca tagctgaagc catacctttt
    17281 agttcttctt catgcttagg atggacttct aacccttttg attcgatggt ccccaatgcc
    17341 atcggtaaaa tgattggacg aacaaatcca gcaactccac caaaactcac gttaaaagcc
    17401 gcaaagatca ttcgaaagat cccataaata tctacaatca taccagcaga tactttcttg
    17461 aatcgcttga tcaaggaagc cgctgattct ttcagaccat ttctttcaag cgttcctgtt
    17521 gccaacataa tgatgataaa aatcgccatc ccgcgattgt ttacaaaact tgtacctaaa
    17581 agttctaaca ttccttgaat gccaagaccg ccagtcaaag ctgtaacaac taaagcaacc
    17641 attacgatca atatcgagtc taatttaaat gcaaacccga gaataacaat caagacgcct
    17701 aaaaggctaa gataattttc catatatctt cctccataaa atgacaatat ttttttaatt
    17761 ataaagcaaa acacataaaa aatatagttg ttttctcacg aaatagacac tatttttaaa
    17821 tatttttcgt tattttttta tcacaaaaat tatcttactt attgtaaggt aaagcttttt
    17881 ttaatttatt gcccgataat atatagaaat aaggtctagt tactgttttt tttaaatgat
    17941 taataaataa caacttcttt ctatgaaatt gcaaagcatt catcttcttt tccgctaacg
    18001 atatatccgt cagtgcttgg tacactttac taaaaagtat gagattgccg atatctggat
    18061 aggtgtgcta tactacagaa aaagatatac aatctgccac cgggtaggat aaagaggatg
    18121 atcattccat taggtctttg aagggatgat tttcctcttt ttgtgtattt ttttatagtt
    18181 aaggaggaat gtaagtatgg catggatgga attaatcata gcaggaattt tggaagtatt
    18241 ctggtcaacg atgatgaaat ggagtgatgg tttttctaaa atcaattatt ctttttacac
    18301 agtgattggc atgattgcta gtttttactt tttgtcaaag gcaatcaaaa gtttgccgat
    18361 gagtctctct tatcctatct ggacagggat tggcgcagtt ggttcggtca taattggtgt
    18421 ggtcttgttt catgataagc tgaatctttc cacttggttc tttgtgggga tgctactcat
    18481 cagtatcatt ggcatcaaga ttactagcgg ccactagaca cttggaataa gtactgatca
    18541 gaaaaaataa gcctttttat ttaatattca atttttttat gaaaaaataa gaaataagtc
    18601 caatgaccta gcgacttctc cactcatcag gtgtatgctt gtactatcta tagaaaagga
    18661 gtgaatattt ttgaaaagtc tttcggtcca agaattatcc aagaactttg gtcacaaaca
    18721 agccctcagc gatgtcagtt ttagcttatc ccctggcaaa atcgttggat tagtaggtcc
    18781 taatggcgct ggaaaaacaa cgatcatgaa agctatttta ggactgatcc attactcaga
    18841 tggaacaatc tgtattggtg aaaatgagat ttctccctct agtcataaag ggttggaaca
    18901 agtaggagca ttgatcgaat acccgggtat ctatccattc ttaacaggct atgatcatct
    18961 gaagttattc tctgaaacca acgatgtatc tgctatcgac actatcgtga atcagctcaa
    19021 gatggaaaag tacattcaca aaaaagcgaa atcctactcg ttgggaatga aacaaaaatt
    19081 gggaattgct cttgccttac tgaaccatcc gtctatcgtt attttagatg agccgatgaa
    19141 cggtttggat ccacaagcaa caagagatgt gcgaaaaatc attaccgact tggctactca
    19201 gggcacctct ttcttgatct ccagtcactt actcagcgag cttgaaaaaa tggtcgatga
    19261 gctgatcctg atcaatcaag gaaagatcat caaacaatgt acaatggctg aattgaacca
    19321 aacagcgcaa gatttcatcg ttatctctac aacaaatgat ctagctgctc gaacgatctt
    19381 gacagaagct ggatatactt tggaagatcc tgataaaatc aagcttttaa aagaaaacga
    19441 agaattatta ggaaccgtga tccagctatt gtctgcacaa aatatccatg tgacagacgt
    19501 ccagcatctg acgaatgatt tggaatcttc tctattggaa attctggatt cagtaaaggg
    19561 ggaagaagaa aaatgacatt gcttgtaaaa caagaattat ttaaattgat caagaaaaag
    19621 tcaactgctg ttttatctgt tctattagtt gttttgctca taggaacagc acttctagcc
    19681 aaaaaataca cgacgatcat tgatccagtt gaaatgactg ctcagctttt tagtgccaca
    19741 tcttggattg tctttatcat gattgcagct gcaagcacga tcatttcgat ggaagcacaa
    19801 tatggtacat tgaaaaatct cctttatcga aagtattctc gaggagaaat attagtaagc
    19861 aaatggatca cattagttat ttattctgtt tatttatacc ttttagctat tattgtcact
    19921 gtgttgatga aactgattct tttcccttcg atttccttca cggagaaggt ttctactggt
    19981 caaacactga tccaaagctt gttcacttat actttgggta gttatatcgg tttatggctg
    20041 attttaagtt tagtgttgat gattgcttgc tttatcaata gttccggcgc atccatctca
    20101 gcaggaatcg tcttttattt tgcttcgtca atcatatctg gtatccttat tgcactcatc
    20161 caaaaatggg agtggatcaa atggaatccg atcagtatgt tgaatctgca aaaccaaatt
    20221 ggaaacgaag agatcatgaa gcaattgact catctttcta ctaatcaaat gctattcggt
    20281 aatttagctt acatcgtttt gttcttagca ttaggatatc tcgtatttaa gcgaaaaaat
    20341 gtatgatgac tcatcaaaaa agaggctgtg aaagagacgt tcagccttat tgccgattgg
    20401 ctgtctctta aacaccgttt attctgaaaa aggagctgtg acaacatttg tgtcacagct
    20461 cctttcctag tatgtttttg aataaacgac aggctcacaa cctctcttta tacttctttt
    20521 atacttctat acgtgaagca tcccagtggc aaataaaacc attgcaatca ctccgaccat
    20581 cgtcacacct ataagtaaaa tcttatctaa gtggatatgt tgtacaggct cgttttgctc
    20641 cttacgtgct ttgaggtaaa aataaatgcc tggcaagaaa agaacaagaa caagcattac
    20701 ttcattaaag gctacgacta gcatagccca tacttgaaag gcacttgcta aaagccctac
    20761 taaaaattgg acccattctt tccgctgata agaaagtttc atttggtaca atcctaagaa
    20821 aagccacgtg aagaaaatag ctgctgtacc aagtgtgtaa gcaaagttat aagcactgtc
    20881 agtgaataat aatgaaagta aaaagacatt cgtacataac gtcgtcaata cgatagcata
    20941 agttggtgcc ccatttttgt tgagttttcc ccatgcttta ggcaaaagtc cgtcttcagc
    21001 catgtttccc attgtttcaa tcggtaagat cgtccatgag agccaaacac caactaaaga
    21061 aatgatcaaa ccgccgttga tcacgactgc tccccattta ccaaccatca tttcaaacac
    21121 atagcccata gcaggctgcg ccttgatcgt ttgcagctga ttcatcgtca ttgtcccata
    21181 tggaagcatg gaaaccaaga cgtaaataat aatcaagccg aatatcccta gaatcgttgc
    21241 tttcccaaca tctgattgtt tttttgctcg tgaacctacg acagaggctc cttcaatacc
    21301 aacaaatacc caaagcatca ccatgatgca actcaatact tgactggaaa acgggatcgg
    21361 ctgtccattc gcattcaata taatgtcgct agaaaagtta tcaatgaatt gttggatcga
    21421 aaacgtgctg atagctacta caataaataa aaataatggc actaatttac agaatgtgac
    21481 gatagcattg acgaaactag cattttcgac tccccgattc actagccatg catatcccca
    21541 taaaaagact gtactcatca cgatcgatgc cagattttgc ccaccttcaa atactgggaa
    21601 gaaatatcct aatgcgctca tcaacaatgt tgcaaaagct acgttgccta accagcatgt
    21661 gagccagtaa ccccaaccgc tgataaaacc agcgaaacgg ccaaaacctt cttctgcgta
    21721 actaaagatc ccgcctttta aatctggacg ttttttattg atattattga tcgacaagga
    21781 gagcatcaac attgctgttc ctacgagtac ccaactgaaa atagctgggc cgccagccga
    21841 tccggagatg tccgtcataa taccaaatac gccacctcca atcgctgaac caattactaa
    21901 ggcagcaagt ggaattaaac caattccttt tttctgttgc tctgtatcca tgtaagcatc
    21961 ctccaaaata aaaccgcttt tatcaaaaag tataacaaac cttttttatt tttacttaat
    22021 taataaaaac tttaatagaa atataattct accggctttt ttctcattat acaagcaaag
    22081 cgcctagtcc ctttccaaat tacaccacca aaaaacttaa aaaagatgct atactaaaag
    22141 gaaagaattg gaggatgatc catgaacatt ttatatatat cgatttcagg aaatacgcgt
    22201 gcctttgcca aacatctagc agaatatgct gaaaaaatgc atgcagaaga tcctgtcaat
    22261 cctgaagtta ctttaaaaga aatccatgaa aatagtgatt ttacgaaaga aacagaacca
    22321 ttttttactt tcgttcctac ttatttagac ggcggaaatg gtttagataa cggtgataca
    22381 gaaatcttga ccgaaacgat gcgtgaatat ctggaacatg aagacaatca taaactttgt
    22441 cttggtgtag tcggtagcgg aaataaaaac ttcaataatc agtattgtct aacagccaaa
    22501 caatatgcac aaacatttgg ctttcctttc ttggcagatt atgaattacg gggaacacca
    22561 tctgatgtga cacgaattta tcagatttta gcagaaaaca ataaataata aaaaagaaga
    22621 agctgaaaaa tagatttcag tttcttcttt cgtttctatt gtttctatca tattaagctt
    22681 tgacatccat cacaggtgct tttgcttttg ctttacctgt tttttccaag acaaagtttt
    22741 ttacacgatc catattggtt accaagacga tcatggatgt ttctttgcct gctgctttga
    22801 tcgcttctaa gtcagcttct gctacaagcg tatcaggtgt cacttgctgc ccttctgtta
    22861 ctttcacatc aaatggcgta ccgcctaagt caactgtgtt gattcccata tgaagcaaga
    22921 tttctaaacc atttggcgtt gtgatcccaa tagcgtgttt cgttgggaag acagagctga
    22981 ctaccccagt aactggagaa tagatatgtc cgttttctgg ttctacaaag tagccttcac
    23041 ccatcatctt ttgtgcaaaa actggatcac ttgctttatc taaagaaaca actgttccgt
    23101 cagcaactga tgagaggata gtcacacttt cagctgaagt ttgaggtact actttttcag
    23161 gcacttcatt tactgtggct gtttcagtcg ctaattcttc tttttctaaa cggtctttag
    23221 gaataccgaa gaagaatgta gcaacgaagc caccagcata agctgccaat aatccaagga
    23281 tgtagcctaa ccatttaccg tcagagatca atgggatcaa agcggctcct gaaggtccaa
    23341 tagcgatagc cccgacattt ccgatcattc cgatcactgc cccgccgata cctccaccga
    23401 tacaagcagt aataaatggg cgtcctagag gtaatgttac tccgtaaatc aatggttcgc
    23461 cgattcctag gatcccgact ggtaaagctc ctttgatcat ttctgttaat tctttatctt
    23521 ttttgcagcg aatccataat gccaatgctg cacccacttg tcctgcacca gccatcgcaa
    23581 gaattggaag caatagcgta cgaccagttt catcaatcat ttgcacatgg attggagtca
    23641 aaatttgatg cagtccgaac ataaccatcg gcaagaataa tgtgcctaga acgaagccgg
    23701 caaatgctcc accaacgcca agtacccagt tgatcccacc gaccatgcca tcagaaatga
    23761 aacctgctaa aggcatgatg aagaaaattt caatcagacc gatggcaatc aatgaaagag
    23821 ttggtgtaac gatgatatct accgcatcag gtactacttt atgcagtttt ttctcaacga
    23881 ttgacaatag ccaaacagcg aagatgacac ctaggatccc accttgtcca gctgcaagag
    23941 cttcaccagt aaataagttt ttcagtggtg cttccggatt catccctgtc agcatcacaa
    24001 cggccccgat aactccacca agagttggtg ttgcaccaaa aacttgtgca gcattgatac
    24061 ctgtatagat aactaggtag ctaaacatcc cgtttttcaa gatgttcatc acatcgatat
    24121 attgttgcca tgttgctgca tcaagtgttc cggctgtgac taagtttgct aaaactgcgg
    24181 caatccctgc cacgatccca gtaccgacaa atgcaggaat cattggcaca aagatattag
    24241 aaatgtcttt taataccgat ttgattttag atggtttttg tttcgatttt tgtgccgctt
    24301 tcatttcttg tgcccgttcg tttacacggt cttttccaga tgctgatgaa tttgctgtag
    24361 ctgtacttac agaagaaagt ttttctccta atttcacgcc tgccaaatca accatttgct
    24421 gtgctacttt gttcactttc ccaggtccga tgatgacttg aagctgttca tcttctacta
    24481 caccaagcac tcctggaatc gcttttaatt cagagacatt tacaagatca tcattgatga
    24541 tcttcatacg cacacgagtc atgcagtgga caatgctttc tacattgccc atgccgcctg
    24601 cccctttata aatttgtttt gccagttctt ccaaagtcag ttcgtttttt gccatggtct
    24661 tttccccctc ataaggtccc ttttacaaat ccgtttgctt cagctaattt tgcttgagct
    24721 tcctctttat cactatttgt caaaatcatg acgatagcca gcttaacatt ttgatctgct
    24781 tcttcaaagt acttttcagc tgtttcgtaa tcagcttctg tcgcttgcat gatgattcgt
    24841 tttgagcgtt cgattagttt ttcatttgtt ggtttgacat cgaccatcaa gttattgaat
    24901 actttaccta taccaatcat actgatagta gaaatcatat tcaagataag tttttgtgct
    24961 gttcctgact tcaatcgagt agagcctgtc aaaaattctg gacctgcatc gacttcgatt
    25021 gggaaatccg cgtgtttact gatttcggct tgtttattgc aagaaatcgt tcctgtgaca
    25081 gcaccgatcg attttgcgta atctaatcca ccgatcacat atggtgtacg accgctagct
    25141 gcgataccaa taactatatc attttttgtc aaattcagct tgattagatc ttcttgccct
    25201 agctcataag aatcttcggc cccttcgaca gctacagtca ttgcttcttc tccaccagca
    25261 attagaccta tgaccatttc cggttctaca ccgaatgtcg gtacgcattc agcagcatct
    25321 aacacaccta gtcttccact tgttccggct cccatataaa tcagacgtcc acctttttta
    25381 aaggactcaa tcgtgttagc aatcactggt tcgatacttg tcagttcttt ttcaaccgca
    25441 gcggccactt tctgatcttc tttgttcatt agttgaacgg cttgagaaat actcatctca
    25501 tctaatccaa aagtttcttg gtttctgcgt tccgttgtta ggttctctaa attgattttg
    25561 ctcattttta tcttccttct tttcttataa attgatagtt cataccagct ttgatttggt
    25621 tgatcaatgg tagctcttct ttgataactt tagctactac attcactttt tcatccgctg
    25681 gcaaatcata tttggttaat tggatctcac ccatatagcg caaatacttt tcgttatcta
    25741 aagtaataga ccctttcata cgcgtagctg tatttcttgc tgggataggc ggaatctctc
    25801 gaaaacgtgc atctacgctt cgtatgacat ctcttgcatc gtcttgccga ttcgtatgct
    25861 tccctaatat atattcgtaa aattcttcat ctacaggttc cgtatggagc aagactgtct
    25921 gttctttttg gaaagaagca aattgctcct gaacgttttc tgacagacct gcatctccga
    25981 tgtaaacaat atccgtgtta cttgctaata gatctagagc gcctgcaaga ggatggatcc
    26041 ctcgatgttc ttccaaagtt ggcaatcctt gatatagtgg gcctctcaac tctgtatctc
    26101 ctggtacaaa accttggaca aggagacctt gaattttgag ccattgattt tttttctgat
    26161 accattcttt gtccagccct gtttcgggac gtggataata attatgccaa gcttcaatct
    26221 gtgagaaatc agcttctgct tctttcaatt catcgatatc tttaggcgtg atcgtgctag
    26281 cattcaaact gattttcaat tgatgtgacc agtcggcaat ctgctgattg gaaatatgat
    26341 aatccattct taaacctgtt acaccaattg ctttcaaagg cgttagatct tctaatgaaa
    26401 aacccgctcg ttccaatgcc tctcctgaaa tatcgaccat caattctagt ttattctttt
    26461 tcgcttcgct tcctagttcg atcaatcgct tttgatatgc cgaaacatca tcttctggta
    26521 tatgcatgga agtgaaaata ccgacaaagc cattggatgc catttggcgg atatactgtt
    26581 tcttctcttc tgacaaagaa tcgttcataa atattgaaaa gccaaacata ttatccctct
    26641 ttttctgtat ccgtcttcat ttctatgact agagtatata tctaaagaaa caaaatttca
    26701 atacttttat taaaataatt aaatttcatt tctaaaggtt gagtttatat tatcaaaaga
    26761 attgtcataa cctaaaaaag gcactgctaa gcaaaagcag tgccttgaaa tattttattt
    26821 aaataacaca aaaacataat tactcataag aaaccaattc tgtattatct accatgaatg
    26881 taaagaaccc ctcattaggc atcggatgaa aataagcatt gatcactctt atcaaggcat
    26941 tatggcaaac taacagatag acattttctt cgtcttcgat gcattctttc aataaaggaa
    27001 cgatccgtgc atacacatct aagactgact ccccatttgg gaatcgtaca gcgaacgcta
    27061 aacgtgcttt ttgaaagttc tcatctttgc ttggcagtcc atcataatcc ccaaaatcca
    27121 tttctaccaa tcgttcatca acggtcagcg gcaagctgag acgatcagca actgcttgtg
    27181 ctgtatctct tgctcgttga agaggggaat ggatgatttt cgtgattgga acaggcaaat
    27241 ctactacctt ttctgctagt ttctgtgcct gcatctgtcc tttttcagtc agcggcacat
    27301 ctgcccgtcc gcaaactaat ccttgtgcgt tccaagttgt ttctccgtgt ctcgttacat
    27361 aaagcatgtg attctctcct tcgttggcaa agttcccctt aaccatacct tgttgttctt
    27421 gagattacaa gggttagatt ctctcaagag aaataatctc agtagatact ttatccagga
    27481 aggtttgatc atgttccact agtaacatgg caggtttcac gttcaagatc agttgttcta
    27541 attgttcttg attgaagaca tccaaataat tcaatggttc atcccatgta tatagttcag
    27601 ctggctgtga taaagattta gccaattcca cttttttccg ttggcccata ctcatctgct
    27661 cgatcttgtt atgaaaaaca tctctttcca tcccaagctt tcggaggttg ttcaaaaatg
    27721 cttggtagtc tacttggttt ttctctgcaa attccgccaa cgttcctcga ttgtcttcat
    27781 aattttggct tgcataacta atgctcagat gttttggctg gtatttttct cctataacct
    27841 tgccgttgaa tgcccccaga agataatgga taatggatga ctttcctgca ccgttaggac
    27901 ctgaaatcgc cacccgctga tgaggctcga ttgtaaaatg aattggctcg aataacagat
    27961 tttcataccc taattgaaga tcttctacgc ttaaaagtcg cttatggtga gacgcttggc
    28021 tattcatcgt caaagaatcg atatattcga tatcttttaa tagtttttct ttctcgctga
    28081 tctgggtctc catccgattc acgattgctt tggatcgttt catcgtccgt gcagcatcag
    28141 cacccactgc tcctttattc actcgtctag attcagtatc gatgaatccg acttgtttct
    28201 ttgttttatc tccttctcgg gaacgagacc attcggcttt ttcagctgct gttttcttta
    28261 gcctactgac ttcttttttc aatttttcat tttgagccat ttcaaattca tcacgaagtt
    28321 ttttctgttc ttcatagata gagaaattcc cttgataaag ttccagttga cttttttcga
    28381 ttgctaaaac atggtccact acttcatcga taaatccccg gtcatggctg accacgatga
    28441 agccttgttt tttctttttc aaataagccg ctacttgttt tctaccagag atatccaaat
    28501 gattcgttgg ttcatcgatt aacgggaaat gagtgtcatc cacaaataaa agtgccagta
    28561 ggacttttgt cttctctccc cccgatagtg tgctgaattc tctccataag atttcaggat
    28621 ctgtttgcat caattggagc tctctttcga tttcccatat ctcaaaatcc gtaatatcat
    28681 ttaacacgta ataggttaaa cgttctttat cttttgtctg ttgcgggaaa taggcaaatt
    28741 cttgctgatg gattacttgc ccttgataag gtagtttgtt ttgtagaata ttcagtaaag
    28801 ttgtctttcc tcgaccgttt cgtccgataa gtcctagttt ccattgtgtg tcaaaattta
    28861 gatttgcttg ttcaaataat aatgtgcctt ggctgtcgta gccgaatgtc agatttttta
    28921 tttcgatttt agacattttc catcacctcg taaaaaaaga ccagtcctat tttcagaact
    28981 ggctaaagag gatgcaaggg ttggatacac acaaaaagac ccatacatcg aaaaaaccaa
    29041 gccaatcccg aaaatctgca cactgcttcc ttgtctccac aaggtacagt ctgaatgcag
    29101 ctttcatcaa tcgacttaat ttttcaatgc acggatccct cactttgtcc tatatttgaa
    29161 attacgatag cataaagaaa atgattttgt caactacttc gggaggatgg tgaaaaatct
    29221 gctaagtgtc tgtcctaaga tttttgtttt ttctaatgtt tgcctgtgtt ccattgcttc
    29281 ttctaaacct attggaccca aatgaatact taagacaatt gggagaaaat cagaaagtcc
    29341 ttctagctct tggtctctac ttccgcaaat agcgattatt ggttttcgat atttttttgc
    29401 aagcactgct acaccgtatg gaacttttcc gtggatcgtt tgctgatcga tccgcccttc
    29461 tcctgtaatg atgacatctg cttgttcgat ctttttttcc aatccagtga tttggctgac
    29521 taaatcgaaa ccagaaacca tcttcgctcc caacaaaaaa agggctccac caataccgcc
    29581 tgctgctcca cttcctggaa tatcatctaa atccacctcc cagaaatctt ttatttgctg
    29641 agcaatcttt cctgcttgtt tatctaagaa agctagcgtc gtatctattc ctcctttttg
    29701 tcttccaaat tgccaagcag ctccttgttg acctgtatat ggattggtaa catctgcagc
    29761 gataatcaat tttactttag aaacaagaac gtttcttcga tcaaaatgaa gttttttagt
    29821 agataataaa ggatttcctt ctgtgtaccc ttctaaagaa gcacccaagg attggagtaa
    29881 tcctagacca ccatcgctac acccgcttcc tcctaaagtg acaataattt gttctacttc
    29941 ttgaagcagt gcatctttaa taagttctcc taaggcataa ctggaagcaa gtcggatagt
    30001 ttgatccgtt ggtttatcaa gtagatctaa ccccaatgct tgtgcagatt cgatgactgc
    30061 ggtgtttttt ccttgccaag ttgtcaataa atagctgatt tttcgctgac ggaataagag
    30121 atccatccca tcaatggtac gccatgttcc cctgagcgcg taatagattg cttctgcagt
    30181 attttctccg ccatctgcaa tcggcacatt gatttttctt cctttacgat cttcccagcc
    30241 atttagaact gcctgattta gttcaaatga agaagcactt cctttaaatg aatcaattgc
    30301 cgccaaaata tccatctgta tccctcactt tcttcttaag taagacactt tttttcattt
    30361 ttttcaaaca aaacaatgct attttcttcc atttttctat atactaaaag ggaactcatt
    30421 gaataaagga gagaaaaaac atgaaaatcg caatagctgg ggccggagca atgggcagcc
    30481 gaatcggatt gatgctacat caaagcggaa atgaggtcct cttgatcgat cgttggcctg
    30541 ctcacattga agccattcgt acaaatgggt tgattgctga ctttaacggt aaagaagtgg
    30601 tcgcaaaact gccaatctat tcaccagaag aaatcatcga aagcaacgaa cacgtggact
    30661 tgatcgtagc attaacaaaa gccaatcaat tagatgatat gttttgttcg atccaatcca
    30721 ttattactga caatacttat gttttgtgtt tactaaatgg attaggtcat gaagatgtac
    30781 tggaaaaata tgtgccaaag aaaaatatct tatttgggat cacgatgtgg acagctggtc
    30841 tagctggtcc cggaaaagtc acattgttag gtgatggaga aatcgaacta gagaacttgg
    30901 aaccagaagg cgaagcattt acaaaaaaag ttgtagaagt ctttcaagaa gcaaatttaa
    30961 atccgatcta tagccataac gttcgttatt ccatttggcg aaaagcttgt gtaaatggaa
    31021 cattgaatgg tttatgcacg attttggatt gtaatattgc tgaactaggc gcgcaaaaag
    31081 cggcagagag catggttcga acaatcgtat ctgaatttgc ttctatcgca gcaaaagaag
    31141 gaatcatact agatcaagaa gaagtgtacc aacatattgc ttctacttat gatcctgaca
    31201 acatcgggtt gcattaccca tctatgtacc aagacctgat caaaaaccat cgtttgactg
    31261 aaatcgacta catcaatggt gccatttggc gaaaaggaca aaaatatgat attgctacac
    31321 catattgtgc ctttttgacc caattagtcc atgcaaaaga aggaatcctt ggcgcagaat
    31381 aaaaggctct ctgatgagaa tcagctgaat cagcagctgg ttctcttttt ttaagcccaa
    31441 taaaagatca aaaagaaaac acaactctca tgatgccata agaattgtgc ttgtttgttt
    31501 cagtacataa tctcttcaaa atgtaggttt tttatttgtt ttcaacagag gagaggtcat
    31561 attcgtattg ctcataaata gtggaatcgt tagtgataaa tcgttttgcc caattttctg
    31621 catcataaaa ttccaatagc tctgatagga ttggcttaaa tggtgtatgc agaaattccg
    31681 gtaattcatc taaatcacgt tctcgaagca aaaaaatatt ttcaggacga taaaaatgat
    31741 aatgagcaat cgcttgatta tccgtcacta gtttcttttg aaaatacatg gattcaaatg
    31801 tccgcaaagt cactccttgc tgaccctccc gcaacagttc cagaatcccg cgcgattccc
    31861 ctgttttttt caggtactct tcataagtaa gatatccagg ttgttcattc cctcgatgtg
    31921 gaagaatgaa atagttggtc gtaacatctc tttttataaa ttcctgctta tagctttctg
    31981 ctcgttcttt tctcccatta ttcgttgcac caaaaaatag atccgtcttt ggttcgctag
    32041 aagaaaaatt catatgtttc gaataaaatg aactattatg tttcagccca agttcttttg
    32101 cttccaaaaa atcaaaatga taaatctcat cgattgccgg ttcatcttgt gcctgcttca
    32161 gcatcgcctc gtgttctgct ttgaagtgat tccaaaaaaa taacacaatt tttgcattgg
    32221 taaatgggcg cacgcgtcga gccatctcca tatcaaatcc ataatctaaa aaaacgatca
    32281 gctgataatt tgccaactgt tgtctagctg atttaatgaa ttccgactgt agtaaatctt
    32341 ttccggacca aacatctaaa gagcggatgg aaggcaaaaa ataaagtgat ttattttttg
    32401 caactagcag tacgtcattt ttgttcatct tttccgcctc actttctctg tcactttttc
    32461 ctatgatagc ctgtttaaat agtaaaaagc cagtaaaacg tttcctatat ttgtatgaaa
    32521 atttaacatt tgtatgaaaa tatgatgaaa taaatcattc ttctattaaa attcgcctaa
    32581 aagttttctg aatagttgta attgtctgaa aatttgttat cattagtcat tgttaaatat
    32641 tgctatttat tcttaatata aattttgatt gtgaatttaa aagaaagagg tcatttatgg
    32701 aagataaaaa attgaaaaaa caacttagct ccagacatat caccatgtta gctttaggtg
    32761 gagcaatcgg tgcaggtcta tttaaaggaa gtggcgaagc gattgggatc gccggccctt
    32821 ctgtattgat tgcttttttg attggtgggc tgattttata tatcgtgatg aaaggtctgg
    32881 gaaaaatcgt tttaagcggt ggcgacacgc atcacggatt atctggtttg atacgccctt
    32941 atctaggtgc tcattctgct gattttactg attgggtcta ctggtctatg tggattatca
    33001 atatcatcgc tgaagctgtt gcagctgctt cctttttgca gttgtggttc ccgcacattc
    33061 cagcctgggt atttgttttt atgttggctg ttttaactac gatcatcaat ctttattcgg
    33121 tacggttatt cgcagaaaca gaatattggc tggcttttgc taaaatcagt gtcattatct
    33181 tactgatcat ttttgctact tatcttgtcg gtcagcaaat gttgggcaca ggcgttttcc
    33241 ctacccttca gcaattgact gaccatggtg ggtttactcc tcatggtatg aagggaatca
    33301 tcagttcttt gcttgtagtt atctattctt acggcggttc tgaactgatt gctatcacgg
    33361 taagcgaagc agatgatcct aaacgtgcga ttcctaaagc aatcaaaggt gtcatgggaa
    33421 gaatcatttc cttttacatc attcctttgt ttttgctttt gattcttttt ccttggaata
    33481 ctttagcagg cacgaatgtc agtccttttg tgatggtatt tgaaaaaatg aatatcccat
    33541 ttgcagcgga tatcgtcaat tttgtgattg tccttgcttt gttctcatct atcaattcgg
    33601 gtgtgtatgc atcttcaaga attttgttct tccgtttgaa ggatcgaaaa ggttcctcta
    33661 gaaaactagc tgttttaaac aagcatcaag taccgcaacg tgctgtttta ttttgtacca
    33721 gtgttcttta tcttggtgta gctctttctt attttgtcgg tgacaaatta tttggctatc
    33781 tggcaggttc cctttcgtat acagtattat tgatctggat cattatcagt gcggcatcct
    33841 ttgtactggc actaagaaaa ggaacattat gggataaagg aatcagcttt tttgcattag
    33901 ctgtcttagg attgattttc cttggtatcc tgttcacgaa ctccattggg gtaactgtat
    33961 tgactggcct gctttacctg ttcatttatt tcagttatca aaaaaagaat gatgcgttcg
    34021 tattgacgaa tgaatgaaat cgatagaaaa ttttatttta tttatgtgga atagatggag
    34081 ctattgaaga aaggagttgt gacaaaagtc ttgttgcaac tcctttttcc gaataaacag
    34141 tctcatgacc tcttggtaaa cggtgttcaa aaaccctctg tgcaaaataa ttgattgttc
    34201 tccatgctca tgacatgata gaagaaagga atgaaaaaaa ggagtttgtt ttaaatgaaa
    34261 aagtattgga agtttttgtt gatgatcggt gtttcaacgg tagttatgtt tggtatgatg
    34321 tacttgaatg tctatgcgct cgatcatatc ttcttcagtc gtacacgagt attcatggcg
    34381 ttgatgatgg gtgcagtcat ggcagtcatc atgctgttgt tcatgtggaa aatgtatgaa
    34441 aacaaaaaga taaatgttat gatcttagcc gctagtcttc ttgtttttgc cggttccttg
    34501 tttatggtac gaagccaaac tactgtcaac gacacagctt ggatgaaggc catgattcct
    34561 catcattcta tcgctatcct ggcaagtaaa cgagctgatt taaaagatcc tgaagtaaaa
    34621 aaattagcgg aagaaatcat tcaggcacaa gaagaagaga tcgacaaaat gaaaaaaatg
    34681 atcaaagaaa tggaatgacc attatccgtc caaataaaaa aagaggatgt tccagaagtt
    34741 atcagcttca agaaataaga agaagctact tctggaacgc cgtgaataag gggttgtgaa
    34801 aaagctgccc tgcatcaagt aataagaaca gccaaacaaa aatagcttct cctatttttc
    34861 gtttggttag gcttattacc gcagatgcaa gcttttgaac accgtttatt aagaggttgt
    34921 aaaatcagcg ttctgacctg agtattagag agacaaatgg aaaaatagtt cctcatattt
    34981 tgccattttt tgagctaata ccgagggtca gctgattgaa caccgtttat cgagaggttg
    35041 tgaaaaagtc gcttagtttc gcgtattaag aaaaattttg tgaaatggct ttccacattt
    35101 ttgtataaat ttggcttaat accgagaaac tggcttttga ataccgttta ttcgtaaaag
    35161 ggattgtgac aaaagtcttg tcacaatccc tttttatgtt tttattgttc taattgcgct
    35221 gtcttgctta ctgcttcttg cggtttcaca aatttttttg agattcccca acctgtgaag
    35281 gcactgacca tcgaaaacac aggagaaagc aaactgaaaa atacgaatgg caagtaagtg
    35341 agtgtaggaa taccaaatgt acttgctacg aaacttccgg caattcccca aggcactaag
    35401 tagttgatta ctgttccacc atcttctagc gttctaccta atacagttgg atcaaatcct
    35461 gctttttcat aagtttcttt aaatgcatta ccaggcagaa taacagatag gaattgttca
    35521 ccaataaaaa tatttactcc gatacttgtc atcaatgttg taaaaatcaa atttggtgtg
    35581 ttcgtcatct ttcttgatac tcgttccatc acggttgaga tcaagccaaa ttcgatcaac
    35641 aatccaccta atgacaaagt tagaataatc aatgacacag taggcatcat actttcgatt
    35701 cctccgcggc taagcagtga atcgatttgt tggtttccag tatttgaaac aaaccctgat
    35761 tcgatgaccc cagccaactt cgttaaggaa gtttgtgggt tttgaataaa aatcattcct
    35821 actgctacag cgatattcaa caaaatcgtt aaaattgccg gcaccttttt ccatgcacac
    35881 agtaacatta aaaataaagg aatcagtgac cagattgaaa tagtaaagtt tgcttctaga
    35941 acatcagtca cttcacgaat agatgaaaga cttgcggctt tacttgtgtg tcctaaaatc
    36001 atgaataaaa agaaagaaac aacaaatgcc gggacagttg accacatcat atgcttgatg
    36061 tgtttgaaca aatcggcatc aacaatagct gctgctagat ttgttgattc ggataatgga
    36121 gacatcttat ctccaaaaac ggcacctgaa acaatagctc caacaaccag cgctggattt
    36181 aagcctagtg ttgtcccaat accgaaaaat gcaatcccaa tcgttgacat aacagtaaag
    36241 gcactcccta cagcgctacc tacgattgca cacacaacaa atacagaagg gacaaaccac
    36301 tggacactga tcaatttgaa cccaatgacc attagagttg gaatgatccc tgcttgtatc
    36361 catacagcaa tcaatgaacc gactaaaata aaaataaaga ttgggatgat tcctggtttg
    36421 atgccattga tgattccttc gtgcagccaa tctgtcgggt atctttttat cactgcatac
    36481 aacatgacca ttccgatcgc tgctaagatc gtgatattag gtgagacctt taatccgaca
    36541 acgccaatcg caatgcctaa aacaataacc attaatacaa gtgttgcttc taaaaaactt
    36601 ggtgttcctt tttttcccat gataatctct ccttttttag ttgttcttat gttctaaaaa
    36661 agttaagata tcggattact ccgccgcaat tcatccgcga ttcctccttt ataaaaataa
    36721 aaagacctgt tttaaactaa ggacgaatga ctccgcggta ccaccttaat taaaaacaga
    36781 tctgtttttc actttcaaac ttttattcaa atgtatggac tttccatgta attcgtcaat
    36841 taggcttgat cggttcacag cgaccaccga ctttctgaac aaaacaccta accgctactg
    36901 cgtgaaaagt tgacttgtac gaagtttacc ttccataaga tcatttgtca atgaaaaaga
    36961 aaatattttt tcatttttct gaaaattatt tttataactt tcacacacaa gtttattttt
    37021 tactagaaag tagcgccctc ttgttttttt cttgctacta tttcttgatg ttcttgcttg
    37081 attctttcta atagctttgg ctctttcaac agatcaagag ctgtattggc gagtagttct
    37141 gctgcaatcg caatagaagc aaggcctttg tcacttttag cagcagcttt gaattcttct
    37201 gtgtgtccgg caatatatgt ctcagagatt gctaccgtag gctggattgt tggtatgact
    37261 tggctgacat ttcctacatc agaagaaccg agacttgttc tttgttccgt ttctatttct
    37321 tcatctggaa cacctgcttc ttttgcatgc tggaagaata agtcatcaaa agaaggagta
    37381 acgatgacat catcaactgc attttggaac aatccaaact caaaagtcgt gcccgtactt
    37441 atcgcagcac ctcgtacgat attttccact ttttcatata ctttatctaa tgtttgccga
    37501 tttcctgcac gtaaatagaa acgtccagca gcgtaatctg gaatgacgtt ggcagctact
    37561 cctccgtctg taatgatccc atggatattg acatcttttg gcaattgcaa gcgtagagcg
    37621 ttgattccat taaacacttg gatcaatgct tccaaagcat ttactccttt ttcaggtgct
    37681 gctgctgcat gggaagcgac accgtaaaat ttgatgtcga ctggatcatt cgctaaagat
    37741 tctgtcgttt tcccataacg aaaagctgga tggacgcata acgctacatc gacatcctca
    37801 aaaaaacctt ctcgaacaaa gctgccttta gctgatccgt tctcgccccc ttcttcccct
    37861 ggggtgccat atacacggat ttctccacca gtttcatcaa tgaattgctt cactatgctg
    37921 gcggctaata cggagtaagt accaaacaaa ttatgcccgc atgcatgacc aatacctggt
    37981 aaagcatcga attctgccaa aaaggcaatt gtgggaccgg gtttattgga aatataacgt
    38041 gcatcaaagg ctgttcggtg tccagctact tctttttcta cccaaaacct ttctttttct
    38101 aattgtttaa tcaacgctgc tgaggaataa aactcatagt tacttacttc aggatgttcg
    38161 tggatatcta gagcaagtgc ttgatattct ggtaaacgat attggattag atccttcaat
    38221 tggtttgttg agattgttgt tgtcataaaa aattcctcct atgctagtca tttttcttat
    38281 tttctcccga atgtttccca tgcaggcacg cttgatcctt ttgatgtttt ctcgattact
    38341 ttgactgtgt cttctgtttg ataagcgtct actatttttt gatacgtttt attgttttca
    38401 tcttcttttc ttgcaacgat gatattcaca taaggacgtg catggtcatc cactggttct
    38461 aagaagatgg catcagaagc aggattaaat ccagcatcta cagctacacc gctattgatc
    38521 actgaaatgt ctacatctga caaagcacgt gctgtttggg aagcatctaa ttcagaaatg
    38581 tctagatttt ttctattctc ggtaatatca gaaacagtgg gcgcttgtcc ttttgcctta
    38641 tccactttga tcaatccagc agtttgcaat aacagaagag ctctgccgcc atttgtaaca
    38701 tcattaggga ttgctacttt tgctccgtct ttgatatcag ctacatcctt caaagtgtta
    38761 gaataaattc ccagcggtgc attgacagta tttccgatcg atactaaatc agttccgtgt
    38821 tctttattgt aattgtctaa aaagaattga tgttggaaag aattcaaatc aatcgatcca
    38881 tctgctaaag ccacatttgg ttgattgtaa tctgtaaatt tcacgtattc caaattaatg
    38941 ttctcctttt tcaaacggtc tttcacgttg tcccatacat ctgtatcttc tccaataatc
    39001 cctagtttta cgatagtttc ttttttgtca gttgtatctg cttttccttg gctacaccct
    39061 gccaaccaaa taattgctac aaatgtaatg actacaaaac gaataatttt tttcattttt
    39121 tctcctccac tttcaatgtg taattttttt aatcagttga ttactgataa attgacttaa
    39181 aaaaactaag attagaatca ataatgtagc cacaatcgtt acatctgttt ggaatcgatt
    39241 ataccctctc gatatagcaa gattccctaa tccgcctgca cctactgctc cagccatggt
    39301 agtcagtccg atcacgttga tgatagtcaa cgccgagacc cgaatgatac caggcaaacc
    39361 ttctaacaaa tacacacgta aaatgatacc gattggactg gttcccatcg cttctgccgc
    39421 ttcgatcacc ccaggatcaa cttctagcag tgcgttctcg atttgacgag caaaaaacgg
    39481 aacaactcca aaaatcaatg gcactaaagc tgctttcgca ccaatcgtcg ttccaactaa
    39541 gaaacgagta gtcaatgcta aaagagaaag caagataatg aaagggatgg aacgaatgat
    39601 attgatcagc ttatcaagta tttcaaatag cagacggtta gctagtaatc cattagggcg
    39661 tgtcactact aacgtcacac ctaagatgat tccaatcatc ccgccaatga atgctgtcca
    39721 aaaagacata tatagtgttt gcttcgtcgc ttcgacaaat tcatccggaa tcaaataaac
    39781 attgggcaaa tatgttttaa agaaatcagt cattttatct tcctccttcg atcactttga
    39841 tacgactatc taaatcgttt ttttgtaaaa tatttatttt tacaccagat ttgatcaaat
    39901 aatccaatgc ttttttccgc tgtttggttt ctccagctaa agtaacgatc aaactcccta
    39961 acggcgtttc ttgtaataac tctacattgc catataaaat attcgctgtt acttgatatt
    40021 tgctgtacag atgagcgatt agaggttcgt tcgtctgatt tccaatataa cttaattcca
    40081 ccagccattt attggcgatc tgatcggcaa aagcagaatg ggcaatgatc gtttctaatg
    40141 cttggtcaag atgagtagct gttcgaataa aatctttggt caattcttct tcaggattgc
    40201 tgaagatctg gatgctgcta cctttttcaa cgattcttcc atcttccata accgctacct
    40261 tgttgcagat ttctttgaca acttgcatct catgagtgat caggacgatt gttaaaccta
    40321 actggcgatt caattttttt aacaatgcaa ggatctgaag ggtcgttttc ggatcaagtg
    40381 cactggttgc ttcatcacat aataatacct taggttcatt cgccaaagct cgtgcgattg
    40441 ctactcgttg tttttgtccc cccgacagtt gtttaggata agcagatgct ttttcttcca
    40501 aaccgacaag ttccagtagt tcattcactt tttgacgacg ttcctgtttc gattttccag
    40561 aatactttaa agaaaaatca acgttgtcaa aaatagttcg gctttccatt agattgaaat
    40621 gctgaaagat cataccgatg gcctttcttt cttttcgcaa ttctttggga gagagctgac
    40681 tcagattcgt ctgattgaca atgacttctc ctgctgttgg tttctgcagc aaattcatca
    40741 cacgaactaa cgtacttttc cctgcacctg agtaaccgac gattccataa acatcgcctt
    40801 tttcaatcgt taaatctaca gaatctactg cctgtatctc tttttctttt tgtttgaaac
    40861 atacagaaac atctcgcaat tcaatcatta aaattcctcc ttatctaaaa aaagcgtcct
    40921 caagaaaatg aaaatgtcat tttcttgagg acgctttttt gcgtgttacc acctcatgtt
    40981 caagctgtgt tcacacacaa ctcctcttca agtacgatca tactctagca agatatcggt
    41041 cgcagccgtc atcgccttac atctatgctc gggatgaatt gctcgatggc cattttccaa
    41101 tagtcgttcc ttgcttcttc tcagctaccg aagctctctg tcaaaggttc ttctatcgta
    41161 cttaccattt caatgcaaat aatattcaaa aaaaaagtcc ttttactaac ataaactatg
    41221 tcagtaaaag gacgacgtat cgcggtacca ccttttttcg gaagtttcct tccctcaagc
    41281 ccaacatctc aaaaagagag attggcgttc gttttaacgg tcgaacagtt ccgaatttgc
    41341 ctacttatcg acaaattatt ctccaaggcc attttcagct tttcttactt gactcttctc
    41401 accagccaga gcctctctgc aaagtttcca aacttacttt ccttttcaac gaaatcgata
    41461 ttttgttgtt gggattaatc tacatgagga aaactgaaaa gtcaagtacg aaattcaaat
    41521 tattttttct atatttattt ttctgttttt ttatttaaca tttcaataac agttcgaaga
    41581 tcttttcctt ccgcaagaag tttcaatttt tccttttctt cgacggtata atttcggaca
    41641 aaactggaat caggtatcaa aacaacgcct aatcctgctc gtgaagcagc tgttgctcct
    41701 actaaagaat cttccactgc aaaggctgaa ctagcttcta atcctgttcg ttccaaagct
    41761 gtcagataag gaatcggtga aggcttgttc tccgacactt cgtctccgaa tgtaaacgtg
    41821 tccaagtaat cagctaattt aaagtgatcc aagatatctg ttgctctttt cgtaacagtg
    41881 gtcgtagcaa tgcctagttt catatgacgt tcttttaagt ctgccaatat ttcttttgca
    41941 tatggtttta agtggatggc tccgcttgtc agctgttgat aaaaatattc ttcacgcttc
    42001 gctcggactt cctgtacttt ttcagggcta cctgctgctt tcactaaaat atcaaaactt
    42061 tgtttccagt tttttccgcc ccaagcgtca acgatttctt ttgggatatg gatatcaaat
    42121 tgctgaaatc cccaaagcca gccatcacga tacgtttttt ctgtgtcaac taacaaacca
    42181 tctaaatcaa atattgcacc tttcatctat acattaatcc tttccaaaac aatacacata
    42241 gtttagcacg actggtccaa aaagaacaga agcaaagaac cagccttctc gtttataaga
    42301 gttcttggaa tcgacggata tagattttct tcacagctgt cacaagcgcc agataagcga
    42361 tgactgtagc aaataaccat aaccagtaat tgccaggaag tggcatcaag cctaattcag
    42421 caccaaaact tgtaaaagga aggacagaac cgacaataat tcctaatgta gtgataacaa
    42481 acatggcaaa tgttgcgttg ctttggataa atggtacttt cggtgtacgc agtgcatgga
    42541 gcactaaggt ttgtgtccat agtgattcga caaaccatcc tgcatggaat aatgcgatga
    42601 aaatcactcg ctgtgaacta tccaatgtat ggaaacttcc gcccactaca gcaggacaaa
    42661 taacaaaata catcaacaag taagtagtaa tatcaaatat cgaacttgtt ggaccaaagt
    42721 aaaccatgaa ttccccaata ctagatgcat tccatttttt tggctcgtcc aaatattctt
    42781 tatccatccg atcccatggc aaggaaatgc aggaaacatc atagatcaga ttcaaaaaca
    42841 aaagttgtaa aggcagcatt ggtaaaaatg gcaggaacgt acttgcaatc agcacggaaa
    42901 acatattgcc aaaattagaa cttgctgtag ccttgatata tttcatgata ttcccaaaag
    42961 tttctcgtcc agaaagaagg cctctttcca aaatcgtcaa atctttttct aaaaggatca
    43021 cgtctgcaga ttctttcgca atatccacag ctgtatctac agaaataccg atatcagcca
    43081 ctttcattgc aggagcgtca ttgataccat ctcctaaaaa tccgacagta tgaccatttt
    43141 tacgtaaagc tgtcgtcaaa cgtgcttttt gctgaggatt caattttacg aatacttcat
    43201 ggtcttcagc tacttgtgct aattcatgat cactcatttc cgagattttc tcaccggtaa
    43261 ccaattcatt gatctctaga cctacttgac ggcacactga acgtgtaact aattcgttgt
    43321 ccccagtcag aacttttaca gctacaccat gttctttcag agctttcaac gcttgtttcg
    43381 ttgtttcttt tggtggatca aggaaagcaa gataaccaat caaaaccatg tctgactcat
    43441 ctttgactga aaattctcca acgacgcttg gattggtctt ttgtgcgaca ccaatcactc
    43501 gtaagccatc ttcattaagt gactgtactt ttgcaagtac ggcttctttt cgttcttttg
    43561 ttaatggtgt aacagtaccg ccaagatcaa taaatttaga aatgttcagc atttcttcaa
    43621 tcgcgccttt tgtgatcatt tgtgttttac cagctggatc agcaaccaca acactcatac
    43681 gacgacgttc aaaatcaaaa ggaatttcat ccactttttg ataattgatc ttatctgtat
    43741 ctaaagtttc tgttgcttca tcaatgatag ccacatctaa caaatttttc agccctgttt
    43801 gatagtagct atttagatac gcatggcgca aaacacgatc atcttcattt ccttcacaat
    43861 ccatatgata ttcaagaatg attttatctt gtgtcaatgt ccccgtttta tccgtacata
    43921 acacatcgat tgcaccaaag ttctggatgg cattcaaatt tttgatcact gttccttttt
    43981 tggccatcac acttgctcct ttgaccaaat tcgtcgtaac gatcattgga agcatttcag
    44041 gtgttagacc aactgctaca gatagtccaa aaagaaaagc ttctagccaa tccccttttg
    44101 taagcccatt gatgacgata actgctggag ccatcaatga cataaatttg atcagtagca
    44161 tggatgtttt atggatgcct aattcaaagc ttgattgaat tggtttttca gatagcgttt
    44221 ctgctacatg accaaatagt gtttcatttc caacagaaac aatgattcct tccgcacttc
    44281 cactgatgac attacttccc ataaagacaa gattttcgta acttgtttcg ctttgctgat
    44341 cgtcttcaca tactttcgca tgcttttcta ctggatagct ttcccctgtc aatgctgctt
    44401 gggaaatgaa taaatccttt gcggacaata aacgcatatc cgctggtatc atatcccctg
    44461 ctgaaagccg aacaagatct ccacagacga tttcttccat aggaatctct gtgtactttc
    44521 cattacgttt tacagctgcc gttactttca caagtgattt cagtttttca gccgcttgat
    44581 tggaacgtac ggactgaatc aacgtcattg tcccgctgac gataaccata gtgaagataa
    44641 tggctacacc gaaaagatct ttatctccag gagctgctaa tacatattcc gtgatgaatg
    44701 aaataattcc taatgcgatc aacactaatg taaatggcgt gatgtatgct ttcaatattt
    44761 ctacaatgaa tggtgttttt ttgccatatg aaatcgcatt ttcaccgtaa ttttctcttg
    44821 aacgttcgat ttgttcttct gtcaatccat ttgctgatgc atggaatagt tcaaataatt
    44881 cttgtttcgt ttttccagca aaagctgcat agattttttg tgtatctttc tttttttcca
    44941 tctcaatctc tcctttgtgt ccaaaagaca gctgttctcg ctgcttttgg tctttagcta
    45001 ttcatcggat cgatagagaa aaaactgaaa ggggctgaga acagatagat aatagccctg
    45061 gcctttcctc tagatccttg tttttcgaat gactgtcatc catttgttct catctccttt
    45121 actaagtaat tttaattcat gacttccaat catttttcga atagttattt ttccaattag
    45181 accacctcct ttttattttt caccgatggg gatttgcggc aacaaaaaaa cctctcgcca
    45241 aatactcagc gaaaggtttg aaaaagcata ttaaaaaaag cttctcagat ctcatcgttg
    45301 agttttgaca ctgtacaacg taaaaagcag atacctgctt ttagctacct tatgaaaagc
    45361 cttatctcga caattcctgt tctacccatt ggcgtctctc gacgtttttg ggcagtagcc
    45421 tatgtttgta taggagcctc acctaacaaa tcttattcgg ttttccttcg ttaatataac
    45481 aactaaaaaa gaggatgtca aatcaatttt ccatgttttt catacttttt ttaaaataca
    45541 cacgttatat tcctgtctca cgcggtttta tttgtctcat tttccacctc ccgctataat
    45601 agaaatatag taggaaacga ggtgctgtta tggaaagaac acttgttatt atcaagccag
    45661 acggcgtgag acgccattta gtcggaagca tcatccaacg ttttgaagca aagggactgg
    45721 ccattgctga aatgaagttt gaaactatga ctcctgaatt agcaaaagaa cattatcagc
    45781 acttgactga gcgcagtttt tttgatgaac tgatcgatta catgacttcc ggtcctgtcg
    45841 tttatcttgt gctggtcggc gaggaagtga tcgatatcgt ccgtaagatg gttggagcaa
    45901 caaaagctgc cgatgctgtt ccaggtacga tccgaggaga ctacgcgctg ccggggactg
    45961 aaaacatcat tcacgcttct gattcccgtg atgctgcggt aaaagagatc gcccgctttt
    46021 tcccgccatt cgatataaac aaaccgtctg aaaaagcggc gaagtgatac aaattctaaa
    46081 ctgctggtct agttgctggg ttcagcaatg gccagcagtt ttttctctaa ggacctccgt
    46141 tgattctttc ctaacatata ttcgagcact gtgaagaatt cttggtagtc tttcgtcttt
    46201 tcttccccta aagcagcaga aatcaatctt tgataataat ctgccatcaa tgtttcatag
    46261 atcactgtac ttctttcttt atgtgataag ctccgtttca tatcttcatt cacactacgt
    46321 gcctttttca accgaccatt ttctatataa aacgaagtca ggttcattaa aaaagtaaag
    46381 agatactgct catgattgtt caactgtgct aatcgtcgca ttcttttttt gattttcaaa
    46441 taattgttct caatgaaccg atcactgaat atccaaggaa aatcagctag aatagatagt
    46501 tcaaattgac catagtctgg tatctgcatc aagtattctt caatgattcg gcattcataa
    46561 cgtaaaaatt caaattctgt ctcagatact tctgtttttt cgaccatgtg aagattcaaa
    46621 accaaataat acagatcttc tgttttctta aaatgcctac ggttattgct gatctcttta
    46681 taaggatcaa agctgtcttc ttgtacccga tctagcattc gtcttttttt ctttaacttt
    46741 attggttcat ccagctggtt tcgcatccat tcatattctg caagtgtcat gttcattcgc
    46801 tctaaaaatg atctcaatgt tacaaatgac atttttttca ctgaatttgt ctcaatcccg
    46861 actagagaag tcttaaaaca gattccttcc gctaattggg actgtgtcaa cttcttgttg
    46921 actcgaagtt tcttgatcaa ttcaccatca tacataatag ttctcctttt taatttaaat
    46981 ttttccacat tcaataaata gatacgttaa aaaggaaaaa tacacgaaaa aaataaaaaa
    47041 atgttttttt cataaaaaat accaaccttc aagcattaga atgttgtcta actactgaag
    47101 gttggtttga ttgtttattg attatttttt tgctgttcaa cgtctgttct tgttactgga
    47161 tataagttgg ttgttgtttt attaccattt tttgaaaaga cacttgtcga atgttcgcct
    47221 ttttgctttt cgattgcttc attacgttcc gcttcatttt tatagtcata ttttttcgga
    47281 tcaatcgtct caaatccgtt tggcacataa aaccgcaaga gattttcctg attcagctta
    47341 tctgaaagac ttaacgcagt cttgactttt tcctgatctt tggagatttc ctcatcgatt
    47401 cctgctgctt tcgtatcgat gatttctcct gtctgattat tgtaagcttt tcctcctagg
    47461 acggtgtatt tgggtgtcac aaagttccca tttcgaaaag caactacttg atcatgctga
    47521 gaagataata agtctgtacc aaaatgaaga taatctttat catcgattcc caatagatgt
    47581 agtaatgtcg gcaaaacatc gatttctcca ccgtattcat gattgactgt ccctttagta
    47641 taaccaggca tatggatcat caatggcact cgttgcatct gtgcgttgtc aaattcatcc
    47701 catgtatctg gatctttacc aagagcgctt gctaaatctt tattatctgt attcgagatc
    47761 ccaaaatgat ccccgtaaat cacaaagatt gaattttggt aaataccaga ttttttcaaa
    47821 tacgtaaaaa attgttccaa tgattgatcc agataatgtg ccgttcgaac ataattatct
    47881 actgtgctat tgccagtatt caaagatgga aagtcgaaat tcttgtcatc cgtataataa
    47941 ggcgtgtggt tggttacgga aagaaatttc gtgtaaaacg gctgttgtag atgctcaaga
    48001 tattgggcag attctctgaa taaatcttta tctaatatcc cataacctaa cgtttcgtcg
    48061 gattcatcaa aataagatcg atcaaagaaa ttgtcataac ctaagttttt atatacatga
    48121 tctctattcc aaaaactagc tacattccca tggaaaacag cgcttgtata gccttgcttt
    48181 tgtccaagga tcgctggtgc ggcttgaaag acattgtctg acccaagttc tgtgaataat
    48241 gagccttgag gtaaaccaaa tgtgccagtt tccaacatat tttcagcatc acttgtcttt
    48301 ccctgtccta cttcatgaaa gaaattgtca aagctgatcg ttgcttgatt ctggaaaata
    48361 ctatttaaaa acggtgtgac ttcttgtccg tctaccttca tattaatcaa aaactgctgg
    48421 aaactttcta aatggagaac gatcacattt ttccctttag cgatcccaaa tgtttcggga
    48481 tttggctctg cataatgttt ctttgtataa tctaaaactt catcaatccc attactgctt
    48541 gcatgcgcgc gaacactgct agtcattcct gttttgattc cgtcataaat agtatacgca
    48601 tcgattccta gatatttgac aatatatgaa cggtcaaatg ttcgctgcag caattgtgga
    48661 cggttggctt cgctcagcgc tagatttcct gaaaaaataa gccctgaaag acaggtaaca
    48721 gcgatagcca tcggtttgcc gacagggttg cttttgatag gtattttctt gaccttcaac
    48781 caaaccagta gcccaatgaa cacagcgata tccagccagt agatgacatc atggggcttc
    48841 atcaaagaaa aggagcttcc tgacaatcct tgcgacactt tcgaaaagcc taatacagat
    48901 ttgactgtaa tgaaatctgt gaattcccga taaaaaataa tattcaagta caacaaaagc
    48961 gtatttaaaa tatcaatgat caaaagaata gctaacgctg gctttggctt tttaatatac
    49021 aaagaaaggc caaaaaacaa taaggtagtc gcaattgggt tgatccacaa gataaagtac
    49081 tggatcgtac cttccacacc taatgaaaaa tctgcatagt aggcaatgat cgtcttcagc
    49141 cagaaaaaga aaacagctgt caaaacgatt gctaaacgat tttggcacaa ttttttaagt
    49201 tgtgtcacgt atatcacttc tctctattca cattttttct tattttgctc ctgaaaaatg
    49261 aaaatttcct aaaaaagttg ttatcttaag atttttttat tctttctaaa gattattccg
    49321 tccacttttc acagcataaa accgctgcga tgtaagcgat taaactaatg aagagataaa
    49381 agtcttgtgg tgaccgcttc actccacggt attcaaaagc cagtttctcg gtattcgtac
    49441 aaaaaaagag gctgtgacaa aattcttgtc gcagctcctt atttcttgat gcaggacagc
    49501 tttttcacaa cttcttcctt aaacggtgtt ctcctgccaa ctcctcggcc acaagtcaca
    49561 atatttataa aacatgagaa gctgtttttt gaaattgttc cttgtggctc agagttaaac
    49621 ggcaggctca agacctcttg atacacggtg ttcaatcagc tgaccctcgg tattagatta
    49681 tgtcaggacg ctaattttac aacctcttgg taaacggtgt tcaaaagctt gcatctgcgg
    49741 taataagccc aaccaaacga aaaatataag gagctatttt ttgaaattgc tccttgtggc
    49801 tcagagttaa acggcaggct caagacctct tgatacacgg tgttcaatca gctgaccttc
    49861 ggtattagct caaaaaacgg caaaatatga ggaactattt tgccgtttgt ttctctaata
    49921 ctcaggtcaa aacgctgatt tcacaacctc tgtttttcat tgtccatagg attgatattg
    49981 tccttgtgat gactcattcg taataattga ggcttgattt tcttcacttc ccgttatcgt
    50041 ttgtccactg ccagaatctg aaggacttgt tcctgtcgac tcgttttttt gagaagagac
    50101 agttgttttc ttgacttgtt catttgtctt tttccattcc gctaaacgat cggcgaccac
    50161 ttttttgtct actttttcag aataagcggt gatcactttt ccatttttca aacgggctac
    50221 tttgtcgcca acatgagtca aaagcaaaac ggtcaaatgc ttgtctttaa attgatattg
    50281 tctgagagaa atcgcactaa gtacgtcatc gatattaata aattgatttt cttcttttcc
    50341 ttttggcaaa taaatgtcca attcgccttt ttcgtaattg gcagttattt tatactccgc
    50401 ccaccaataa gttgagaatt cttttttgaa attatctact gattctttgc ttgctacgat
    50461 tttttctgtt tctttctgag caagatctgc tgtcattttt cctgaaaatg ctgcggataa
    50521 aataagcagt aagaaaaaac cgaataacca aaagagaaga aacggtcttt ttttcctcat
    50581 gctttcctcc actcctattt aattttgact attctattat atacaaaaaa tgaaatagaa
    50641 agacaaaaaa gttgaaaaag atcgtaaata attgaacttc tttttcacaa aatggtaaga
    50701 atggagaatt tcacgcattt gctctcaact attctttctt aagcctcaaa tccgttttta
    50761 tctgatacgt ctttgaacca atgacccgat tttttgattg ttctttttcc atcttgtgct
    50821 aagtctactg aaataaagcc atatcgattc ttatatgcat tggtccacga ccagttatcc
    50881 atacatgtcc acatatgata gcctaaacaa ttggcacctt cttgaatggc ttgatggaca
    50941 tatttcagat gagattggac aaattcgatc cgataatcat cgtggatcat gccatcttct
    51001 ttgataaatc gtgcttcgtt ttctacaccc ataccgtttt cagaaataaa gcagtcgata
    51061 tttccataat gatctcgtac attgatcaaa atatcataga ttccttgttc atagatctcc
    51121 catccgcgat aaggattcat tttacgacca ggcatttcat aattgtcgaa ataatcctca
    51181 ggcattggac cgtttttagt atcgattggt gtttcttttg cttttacccg gcgtggctgg
    51241 taataattga tacctaaaag atctactgta ttttctttga taaccgtcaa atcctctgca
    51301 tggatcacag gcatgagatc aagttctttt actatctcaa tcaattcact tggaaactcg
    51361 ccttttacag ctggatcaag gaatgaacga ttgaagaacg catctgctat ttgcgctgct
    51421 ttaacatctt cagggtttga ttcgtctctt ggatagcttg gtgtcagatt caagatgata
    51481 ccaataacac caccttgctc catttcatgg taagatttga tggctaacgc tgaagccaac
    51541 gcttcatgat agccaacttg gatcgctttt ttcatatctg actcttctgg ataatgccat
    51601 cgatataaat aacctgcttc gactggaacg attggttcat tatgagtaaa ccattttttt
    51661 actttcgaac caaacaattc aaaacaactt ttggcatatt tttcataggc ttcaaccgtt
    51721 tctcggttca accatccgcc tttttcttgc agatacatcg gcatatcgaa atgatacaga
    51781 ttcacaaagg gttcgatacc gttttcaatc aactcatcaa aataacgatg atagaaacga
    51841 acggcttctt cgttgattgt tccagattca tcaggtatca aacggctcca ttggatagat
    51901 gttcgaaatg aattatgccc agtctgtttc atcaactgta catcctcttg atacttcgta
    51961 taaacttgcg aggttttttc aggtcctact tgatcaaaga acttttgcgg ttcttttttg
    52021 taccaataat caaaaatgtt ctctcctttt ccatcgcctg aaatccttcc ttctgtttgt
    52081 gggccacttg ctgcagaacc ccaccaaaaa tttgctggaa attgatattt tttcatcaaa
    52141 gcacctcttt ttctttttta gttcgtttta gttgattcca tgtatgatat tttccatcac
    52201 aatcactttt tcattttctt cctcttcttt tttgattcgt tttaacagct gttctgctgc
    52261 tcgttccccg attttatctg ttggtggcgt gatcgtgatt ttcggaagga tactcagatc
    52321 gtttttatct aaataatcat agtgactgaa cgcaatatcc ttcccgattc tgacaccttc
    52381 ttgattgaaa cattcgatgg caccaatcga catattgtaa ttgctgacaa aaatagcagt
    52441 tgcccctttt tctaataatg cttttgcccc gtaatagccg ctttttctag aatagtctcc
    52501 tgtaaagacc tctaattgga tcgatggatc attttggacc gcttctttgg ctcctgctaa
    52561 acgttctctt gctacgtagt ctgtttgagt ggcagcaata aatccgattt ttttatgtcc
    52621 ttgttcacca tgatgagcga tcacttttgc tacactttct cgatcattca ctaatattgt
    52681 atcaatacct gctggtcctt ctggacaatt caatgcgata actggaatac tcatttttgt
    52741 gagcatttca aatccagacc actcttcttc ggataagaag acaatcagcc catcgatcac
    52801 atgcttcatc aggtattcaa ttttttgttc aattttttct ggctgatcgg caaacccgct
    52861 taataataag ctatacccat tttcttcagc tactctttcg atccctgaga caacttccga
    52921 cccaaaacgg ctggaaatcc cgtttatcaa aagtccaata gagaagcttc gattattctt
    52981 caacccttta gcaatgatgt tttctttata gtccaacgct gaaatcgctt ctgctatttt
    53041 tttcatgttc ttttccttca gttgctgacc attcaagtaa cgggaaactg ttcccactga
    53101 aacaccagcc atcttagcca catcacggat cgatgccata cattctcact cctgccagtt
    53161 acatttgatt tctctttctt gttgttcgat tatgatgacc gcattctttg catagtgttg
    53221 cttgtcatca atatccatat aactaaagtc ttcagtagag caacttcctc tcactattaa
    53281 ttatacttaa acaagtattt gaaccggttc atttttaata tagcattttt ttaaaagatt
    53341 gcaacacttt tttaaaacgc tttctgaaag tggcggattt tttgcctttt taaaatttta
    53401 ttctaaaatt tactctattt gtgggtgttt tgtgcgtttt tctcttccat ccgtttgaag
    53461 ttttacattc caatggtata atttctttat cctatcaaat gggggaagta ttttgaagaa
    53521 attaatcgta ctatttattt tgtctgcggg acttttgaca ttgactggct gtgatttgtt
    53581 tggcggctct gaccaatcct cggacgaaac aaccgattct tctgtcttaa aagcggaaaa
    53641 agcagatacc accaacagtg tatatacgct aaaagtacgt aaagatatgg atttatccgc
    53701 gggacagttg acatttacag ataaaaaaat ggaatggaca cgcacgtatc agacacaagg
    53761 aactgattct tctgaatcat ctgaagaaaa aacagtgctg acagatatca agatcactac
    53821 caaagatgac gaatatatta tttcaggaaa agaaaataaa aaagaaacaa cagtcatatt
    53881 tacaaaaatc ggtaattacc gtttgaagga tgaggatggc aacatctaca gtctatagtg
    53941 ccgtctgttg gatcttcttt tgtttctccc cttcttttct gctatagtaa agaagcaaga
    54001 tgattgtaaa ggagacgaaa tggatgatcg atagtcctga ttattgtaca tgtaataaca
    54061 acaaaaatat ccatacagaa tttaatgacc aaggaagctt gagcatatgc gacaactgtc
    54121 acaaactagt caaagattca tttaaaacat ttgaatctta tcctgttcaa aattatgtaa
    54181 aaagtagaag aagataaaca aatccaagca aaactcacta tggctgattt ttatgaactt
    54241 caaactcagc ttcttccttt gatcaagctt catcagtaaa acaaacagtg gatcatttca
    54301 gtttacaaat caaagagtaa agatttattt atttcaaata tttgaatata aaataaccaa
    54361 acgatagaaa ggcttattct acatcacgta gtaatttttc tttcccgtcg tttggttttt
    54421 tatttttagc ctaattcttg accttttgca tgctggttat ccgtaaaata ttttccagca
    54481 ggctttcctt ccaattcagc taatttttct tggatctgac ggatcacctt ttttgcatct
    54541 tctggatttt ctacaaaatc gaatttatcc ccatccactt gtattttagg acatacatca
    54601 aaatcttcat accattgatt atagcgggtg ttcaacgttt cataataggt atataacgtc
    54661 tcatcgcttt ctagctgttc atagtcacgc ccacgttttt tgatacgttc tagcatcgtg
    54721 tccaaagaaa ctttgatatg gaccatcaaa tcaggccgtt tttttggagc aacatcatct
    54781 aactcgttta gcatcgtatc taataagcta tcgtactgct gtacttcgat atccgttacc
    54841 cgacctaaat cagcgtttag atggaacaac aggctatctt catagatgga tcggtctagc
    54901 acattgtcat cgttcactaa agcatttttc attgctaaaa atcgcttgtt caaaaagaag
    54961 atttgcaata aaaaagcgta ctgctcagga tttgaataaa agagcggcaa tacttcgtta
    55021 tcttcgacat tttcataaaa tggtttagaa tcaatctctt ttgcaagcat atccgtcaaa
    55081 ctgctcttac ctgcaccaat cgttcctgaa atcaaaatca ctgacataca acccttcctc
    55141 ttctataagt actcgcctac gtaagtttca acaggcaatg tttcaaaatc atattcacgt
    55201 acagcttggt ctgattttaa atacgtatgg agactttgtg taatcatcaa gttcgtaggt
    55261 accgtctctt cttgtacaat gatcatcggt tttttcaaca tagttgccac acctaattcg
    55321 taagccgttc ctggatcgat tgtttgatgc tcaaagtcaa ggatagcaac aacaaattct
    55381 gcatttgtca gttcttccat atctttttcg tatacttcct gcgcccatcc agcgctgaat
    55441 agttcataat tgctttcttg gtgatgacgt ggagagtaga aacttgtgac tgttttgttt
    55501 tcctccaacg ctttttcgat acgacttact cgatcgattt gctcctctga aaaaaatggt
    55561 cctgctaaat atatttgact cattattttg cctccttcaa taataactga tttttaatag
    55621 atactgctcg taattcattg accagttcca atggattgtt ggaaaagatt acttgatcca
    55681 accatttttt atccataaaa tcctcttttg caaaagtttc taataattgt tgcaagccgc
    55741 tgtaataacc gccaatattc aatattccga ttggcttgtc gggcgtcaga ccgattgcta
    55801 tccaagaaag aagttgtgag aattcctcca atgtacctag acctccaggg aaaacgagga
    55861 cagcatctcc cttttcaaat aataatacct ttctttcatc gatcgtttct gtaggaataa
    55921 atgtagtaac atcttttcca ggcaattcag tttcaaaaag cccattcgga tagatacctg
    55981 tgacttttcc gttattttcc agtactgttt tactaatcac tcccataatc ccggagtatg
    56041 aaccaccgta aaccagttcg atttcttctt gtgccatgta ttttcctaac gtttgcgcaa
    56101 taaatttgta actttcttta ttaccaaaac gggaaccgca aaaaacagta agtttcataa
    56161 aaaaacactc cctaactcaa aagtctatct tcattctaca cgtgtttttt taaaataaaa
    56221 gactagattt tgtagttttt tagtggtata taggatagac gccactatat atagtattta
    56281 gaaaaaaatc atttttcagc cattttatag ataaaacaaa aataaataac gtgttttcat
    56341 cgatatgaaa tgacttactt atagaagata ctgggatttc gtcctatatg ccaataacgt
    56401 gtattatttt aaacaacaaa tacttgtttc ttttattaac gaaaaaatca ttttgttctc
    56461 gtgttatgtt tcactgataa atgatgtttc tctaaataaa aaagccgacg aactaaacga
    56521 tcaaaatttg atcatttttg ttcatcagct tctcctaaaa atctttttgt taacgataaa
    56581 tagctggatt tgtaaaaata tcacttgaat cgtcactgct ggaagaaaat tcagtgataa
    56641 ccgcacctgt tgcgcctgcc tggaactagt gtttgatatt gggctcgaac gtgtactgat
    56701 ctctagcatg aagaataatt tcttttttta ctgtataata actttctttc ctttttggaa
    56761 tagtacagga aagttttttt gtttcctttc cttcgacata aggtatacca gaccctttcg
    56821 acaacgaaag gttctcattt ttccttcatc gtcatttcaa ggagggtgcc gatgctctgg
    56881 acagtttcga tcgctcctaa accaaaatct gtatattcga ttctttctaa ctctgattct
    56941 ttcataccat tcctgtctca aggtacatct attgtacttt tttcttgtaa tccattctgc
    57001 ctctcctaac taattgtcaa atcatcccaa gatatgtctt cttcctcttt ttcttcttgg
    57061 atgatttctg cattcggatc tactggtttt ttcaataata aaatggttat tcctgtgaca
    57121 aaagaaccag ctaacaatgc accaatgaat gcccatggtc tggtcatcgt agcgactgca
    57181 aacattcccg atgccggaat acggctatct gcgccccaaa acatgcttaa tccgccacct
    57241 actgtcccac cgactcccgt tgctatgaca ttgcgtgcca agtcgttcaa tacgataggg
    57301 aaacatccct ctgtgatctg acagatcccc ataggaaaag cggtcttcaa tgtatcgatt
    57361 tcttgacgat tgagtatatt tttacgaatg attttcccta agaaataagc gatcgtcaag
    57421 ccgaatgggg ttaccatcga agctaaaatc aatacagtga ttggttcata gattccttct
    57481 gaaaatcgtg ccacaccccc ttatccagaa taaatggtaa tccagaaaca gccgtgtatc
    57541 tgcggtaata agcctaacca aacgaaaaat atgagaagct atttttgttt ggctgttctt
    57601 attacttgat gcagggcagc tttttcacaa cctctttttt tatttatgtt tcataatcaa
    57661 tatggtaagg atgcagctcc gtatggtaga ccgcctccga atattcaatc atttccccaa
    57721 tttgcgtaga cgatttccgt atccgtttga tgccgatctg tgcgtctgtt ttcagaattc
    57781 cttgttcttc ttctgttaaa aatactgccg agaaatcatc agaaaatgag tcaatagtat
    57841 atcctttttt cgtcagcaaa cgatacaaag attctttgcc aaattcttct ctgctgaatt
    57901 gcatcatttc ttgtggaaga taatgaacaa aataaatata aggctgattg ttcaaataat
    57961 ataagcgctt aaaacaaaca gcttgctcac cgaaaaagga aaacaaagga tcttccttct
    58021 ttatatggac caattgcaaa tccagcgttt ctttccggac ttcatatcgg gagttctcca
    58081 agatttgcgt aaagcttgcc gctttggata atcgattgta aggacgattg cttagaaccg
    58141 tcgtcccacg accacttttc tttgcgacat attcatctga tgccagcagt tcgattgcct
    58201 ttcggacagt gattttgctg acttgaaaca gttcttctaa ttcactttct gtcggcaaca
    58261 tcgaaccgac tggatatttt cctgagaaaa tatcttcttt aattttatct gcgacttcca
    58321 agtatagtac acgtgtcctt ttcataacgt caccctttgc tttactatta ctaaaagaat
    58381 agcacataaa aaataaaaaa agaacacaaa tcacatgtga gaagtgtgtt ctttttcatt
    58441 cagctgcttt aattacaagt ttacgccatt tgaggcaatt acttctttat accaatcaaa
    58501 agattttttc tttgatcgat tcagtgtccc atttccttca tcgtctagat ccacatagat
    58561 aaagccgtaa cgtttactca tttctcctgt tgatgcactg acaagatcga tacatcccca
    58621 aggcgtatag cccatcaaat ctacaccgtc tgctactgca ttagccatcg cttcgatatg
    58681 acgacgtaaa taatcgatcc gataatcatc aataatcgtg ccatcctctt ccatatgatc
    58741 aatggctcca agaccgtttt caacaatgaa taatggtttc tggtaacgat tgtataattc
    58801 attcaatgcg attctcagcc cttctggatc gatctgccag ccccattcac ttgcctcaag
    58861 aaacggattt tttactcctc ccagcaagtt cccttctgaa gttgctgctt gtggatcagt
    58921 ctcattgatt gccgtagaca tataataact aaatccgatg tagtccactg gatattcttt
    58981 tagcaactgg aagtcttttt ccgtttgctc taatttttcc ggatcgactc catatttttt
    59041 atgggtacgc gctgtgtatg cagggtattc tccacgtact tggacatccg tgcagaaaaa
    59101 attgaattct tggttttgga tcattgttgc tgcctgattg actggattgg catcgatgct
    59161 gtaagttgtt gcatagataa tcatgcagcc gatttggata tccgaacgca attcgtggcc
    59221 gatttttacg gctttgctac ttgcaacgaa ttgattatgc catgcttgga aaatattttg
    59281 gtactctcct gctccattgc tttttactaa tccttgactt aaagctggaa agtgaaaggc
    59341 cgaattgatt tcattgaaag tcatccaata tttgacttta ctgctgtatc tctctaatac
    59401 tgtctgagca aatcgttcat agaagtcgat cagttttcga tttttccagc caccgtattc
    59461 ttttgccaaa tgaagaggca tttcgtaatg agaaatcgtg atcacaggtt caatatcata
    59521 ttttaagcac tcatcaatca gctgatcata aaattctaat cccgcttcgt taggagtacc
    59581 ttcgtctcca tttggaaaaa ttcgtgtcca ggcaatcgaa aaacgataac atttgaatcc
    59641 catttccgca aacaaggcaa gatcttcttt gaaacgatcg taatgatcaa ttcctcgatg
    59701 attcgggtaa atatattttt cttgatcaat cgtccagtca aattcttcac tgccgataat
    59761 cgcaaagcgc tgcttacctc caggcatagc atctgcaacg gatagccctt ttccgtctcg
    59821 atcataagcc ccttctaatt gattggcagc agttgctcca ccccataaaa atttttctga
    59881 aaaacgtgat tgcatcctga tttcctcctt attttacaat tgccagaaca tcttcgtttg
    59941 caataatctc tttttggtct aattcaagta tatcggcaaa tgcatcagta ttcgtaatga
    60001 caactggagt gattacgcta tagccagctg ctctaattgc ttcgatgtca aaacgaatca
    60061 ataaatctcc tgctttgacg agatcccctt gtttgactaa gatctcaaag ccattcccat
    60121 ttaattctac tgtatccatc ccgatatgaa tcaaaatctc cgctccgtca gtcgttgtga
    60181 tccctacagc atgtccagtt ggaaaaatag tcgtgatctc tccgtctgca ggtgcaacta
    60241 gttctcctac ttctggatca atagcgatac cttttcccat cacgccagaa gaaaaaactt
    60301 ggtctggtac ttcactcaat ggcagtactt tacccgttaa aggacttttt aaggtatgcc
    60361 gtgctgaagt aatcggttct cctgcattcg catgtttgtt ttctaattga ttgtcttgtg
    60421 tttgttcgtc aaatcctaaa atcaatgtac ctacgaatgc aagaacaaaa gcaattcctg
    60481 tagctattac tgctactgtc acatttgact ctacaccatc caccgtatta atgaaagtcg
    60541 gaatcgtcaa taagctgacc aaactgctgg agaaagcttt tactccggaa aatccgataa
    60601 tagctccacc aatacctcca gaaatacaag cggcaatgaa tggtttcttc aaaggtaatg
    60661 tcacaccata cacagttggt tcagtgattc caaataacga agtcactgta gaagaaatcc
    60721 ctaatgctcg aagtttcgta tcttttgttc gcaatgctac agctaaagca gccccacctt
    60781 gtgccaagat ggctggaaga agcattggca tcaatacatc aaacccatat tgttcgatat
    60841 tcaaaaacat gatcggtacg aatccccaat gcatgccgaa catcacgaat acttgccata
    60901 aacttcccat gattagacct gctacgattg gactaaatcc ataaatcgag ttgaagagac
    60961 cgcctaaagc attaccggca accgtcccga ttggtcctaa agcaagaaat gttaatggaa
    61021 ccatcactac taaaacgaca agcggaacta aaatcatttg cagaaattgc ggaatcactt
    61081 tttttacgaa tggctctaat ttactttgaa cccatacggc tagaatgatt ggtatgacag
    61141 aagaagtata accagatggt gaaagaatca ctgggatccc aaagaaactg atagcttctc
    61201 ccgcaccagc aactgctgtg atagctggat acacaagtgc catagcaatt gctactgcta
    61261 aaaactggtt ggctttgaac tttttagctg ctgtaaaagc aagcatgaca ggtaagaagg
    61321 taaagacacc atctgctgca gcaaacaata tttgataagt accgctatca gctgtcagcc
    61381 agcccatcac cgttgccaat gataagaatc ctttcaatac cccggcggct gccatcgccc
    61441 ctagaaaagg tgtaaatata ctagagataa tatcgatcag acgattcaaa atatttttgg
    61501 actcttcttt tccatcctcc gaaactgcaa gaccttcctc atccacgatc gattgataaa
    61561 catctgctac attactgcca atcactactt gatactgacc gccactttgt acgacttgga
    61621 tcacgtccgg gtcttctttt aacttttgcg tatctgctaa agattcatct tttaatctga
    61681 atcgcaaccg cgtagcacaa tgtactaaac ttttgacatt cttttgtcct cctaccgctt
    61741 cccatacacg acgaccaact gcttgattat ccattgtttt ttccttcttt cttttttatt
    61801 taaaaaataa aaacccagat tgaaaaaaac agtcacaaac attcgtgaac ctattttttc
    61861 aatccaggtt ttgcctgcca tacagtaaca atccttatga ttggatgctt tttttctcac
    61921 ttactactct ttgaatatga atcgttaaat aaatctgctc tgcgatcccc atttcctgtt
    61981 tttgcgtttg tcgaagatac tcattgatcc gttcgacaca atgaaacgct tttggatact
    62041 ttccttgaac taatgcgtag agaaattcat cttgctcgtc agatccttcc cctttgagat
    62101 aacgctgggc aaaaaactgc agatgagtaa tgatacgctg ataattcaaa gattcttcat
    62161 cgaacacgat gccgaagaat ttactgatga tactcagtat atctcttacc attgtggtag
    62221 cggtcatcgt cacttgcatg tcttcgtttc cttgttggct attcacaaaa tgaaaggcaa
    62281 taaaaccggc ttcatcctca gaaagttcca cacccgtctt ttgtttcacg aacaaaagag
    62341 cctctttcgc tgcttgatat tctttcggat aaaatttttt tgtttcaaat aataatggat
    62401 taggcagttg gatattttct tttgctcgtg tgatcgcata atgaagatga tcggtcaatg
    62461 tcagataaat attaggcgaa aattcaactt ttagtttatc ttcagccagt tcgactactt
    62521 gtttgaccca ttcgatctcc tctgccggaa tatcagccat cagctgctgg aattggtttt
    62581 tagcaaaaga atctcttaaa acaaattctt tttggaccgc ttctggcgaa atctcgtccc
    62641 caatcttttt ttgaaaagct agtccttttc ccatacaaac gacttcttcc ccgaatccat
    62701 ttttcgaaat gacgacattg ttattcaaaa ttttatcaat tttcattttg cttcgccctc
    62761 tcaagaaaaa taaaaaaacc tagaattcgc ctactgtttc ttagctgaat tctggttttg
    62821 cctgccgtac agtaacaatc catttcttat tcaaaatcat cataccatcg aatttttatt
    62881 tatgcaagcc ttttcatata aaaaataaaa aaactggaac acaagtctat ctagaaaaca
    62941 accaaatcag agatgcacct ctttgcgttt ctcttttttt cagcaaattg gtttttcctt
    63001 atcgattcat atcctttggc tgtttttaat ctgtaacgac ttatgtccca gtatcctaaa
    63061 atgtttttgt ctctagattg aaagcagatc tcatatcatc tgtcgcatct tttatcgatg
    63121 taacactttc cagttctcct tgtacaacta gtcgcgtgac ggcgtccatg tcgccacaag
    63181 taattagtgt gacaatttct tttccctcga cttcattcag taattgggta tctgtaggag
    63241 caactttttc tttaaaaaat gttttgtatg tatacacatt ttctaaatct gtcaaataga
    63301 tcttggcacc catctctaaa ttttctagcg gtgtaaacag caattcaggg ttcgttgcac
    63361 gatggcttgc taaggcataa tttccttttc ccatttcttg atctggagat aatgttcctg
    63421 ctccgtaaag tagtgacgta ttatccaagc ctttgaaaac cggtaaattg attgaaactg
    63481 aagggactgc gatactagca atcactggta gatctgttcc tctcatttgc gacctcatga
    63541 ccccttctgt cgtcattggt tctaccgcat caaagtcaaa actgacatct ttatcgttat
    63601 tctttttcag atcttctttt gttacattcg ctatagcata tttatctcct gtctctctga
    63661 caaaataatc cttgatctgt tcattgaaaa tcaaagctag tcctactaat aacaagagga
    63721 acaagaggat attgactagc catctttttg cttttccttt ttttttcatt ttctctccct
    63781 ccagactcat tttactgttt ttcttttgct ctttccaaca gccgaatgac acatttctac
    63841 aactctgtgt atttttttcg tacacctgcg cttttttcta caggatattt caaattattt
    63901 ttgatcaatt tttcttcaat gatctcatct agatccaggt gaaggttgtc tgccatcatg
    63961 tatgaataga tcaatacatc tgccagttct tctttgattc gttctaattg tgtttctttt
    64021 acttcttccg gcgttttcca ttgaaaaagt tctaacaatt cagatgcttc caaagaaata
    64081 gagatagcca aatctttttc gttatgaaat tgtcgccaat tacgttcatc tctaaactgg
    64141 ttgacttttt ccatactatt catttgcttg ccttcttcca atcacttctt acttgattaa
    64201 tcataccatt tttttacata aaaaatagat gatgctttta aaaaaactcc tgttttcttt
    64261 tatttaaaat aaatgtcata gaaaatcaat aatttaggta gccaccatgt gtatgcagta
    64321 gcgtgtcttc ttcccttgag gctttttgtt tttcgatacg ttcttcttcc caaacagaca
    64381 acgctactag aatctctctt aatgattttc cttcttcggt gagcgagtac tctactttag
    64441 gcgggacttg gttataggct tttcgatgga tactttcatc ttgttctaac tctcttaact
    64501 gctgggtcag catttttttt gtgatcgtag ggatttgctt gcttctccac gcctaaaata
    64561 agcgatattg ctcttccctt tatctggtgt aagcaaagca gttagcattt tgacgatcgt
    64621 gggttccgct tttcacttct tatctactta gtatcatgaa gtatactttc gtactaatac
    64681 taagtagcgg aagtgtcaac tactttgttt aactacatag caaaagaaac agaagggtga
    64741 caacggtcat cacgcttctg tttcttttga atatgctgtg ttgttgtctc tatctccgtg
    64801 tagactttcc tcaaacttat cctttgacag taagtcagta ggctgatttg ctctttctag
    64861 atgccagata catttctaca aaaaaatagt gattctgttt tgaaaattcg atttttagtt
    64921 ctgcattttc gtaaacatcc aacatttttt tcgcactgta tagacctaac ccgccatttt
    64981 ttttagaggt ttttcctctt ttgaccatct ccgatagcgt caaattcgtt ggatttgcct
    65041 tgttcgctat actaaaacgt gatccctctt tttcttccag cagattgatc gtaatcggac
    65101 tctgatcggc tacacgatga tcgaatgcgt tagaaataaa aatagataaa cagcgaataa
    65161 aaacaaccag atcaatcggg attgttttca cttcgacagg aataactact tggatcggga
    65221 ttttctccga ttctgctttt tctagaaatt ttaaaaagac acccctgaca gctggggata
    65281 caatatttgt tagctgttgt atttgcggtt tttcaaaaat agctgcagaa tgatcttcta
    65341 atatttctaa aaattccaac gtttcttttt tattttcctg aagagtaatt tttaatgaaa
    65401 acagtagact tttataatca tgtttgaatt cctctagatg atggtaatat tcttcattta
    65461 tttgatacag ttgaagcgat tcctgatgtt gtctttcttt tacttggaaa ctgatcaaca
    65521 taatggaaaa aaacaaagaa aaaaaactga tgactatcga caaaagagat agaagcagat
    65581 aattagatga gcggaagtga acacttccca ataccaagta aatcacgccc cagcttaata
    65641 aaatacaaat acctccaaaa tagtgttcag ttggataagt aaaaagcaag ttgagaaatc
    65701 tcgtctgttt gtctatactt tttactaata gatagaaaat aaatgcgata agtagtgcaa
    65761 aaaaacttgc tgttccaaga tgtctctttc ctaaataatc catcagatca aaaaccagaa
    65821 aaaagctgag tccagtgata gcaaaaaaaa gattactgat caaacagctg ataaacaggt
    65881 ttttcgtagt aaaataaaaa agaaacatca ataataagcc aattaggtaa ggaaagctca
    65941 ctttagggat aggaagtaaa agtgtcacca ccatcaaagc tatacaacca aagctgtttt
    66001 ttactagcag ttgtttcgaa aagaataaat agatacctaa atctaaaatc aaagtaaagg
    66061 tcaaataaag tgtcactgtt gcgaccatct tattcctcca ttgttttgtt tcaaaatgta
    66121 cacatatttt tttaatagga gcctgcatat gaaaaagtat tttatcatag aagataacca
    66181 gtttcacagc gaatggatca tcagagaatt ggtcaatcat catatcgaga atatcgtgca
    66241 gctcacttct atctctcaaa tcaatcagtt gatccagttg ggcactattg ataatcacga
    66301 tgttttcttt atcgatatcg acttgaagca atcactcaca ggtattgatg tcgccgaaca
    66361 aatacgtaaa aaaaatgcac atagtaatat tgtttttttc accgcttata cgaattttgc
    66421 agtagagatc atcaatcgga aaatccttcc gattggatat atcagaaaag acaggaattt
    66481 atctgaacaa attcgtcaag tgctagaaca gatcaattgg aaagaacagc agatcgtaaa
    66541 tgtcgataaa atctttattg atcaaaaagg tggaagtc
//
LOCUS       DAXLPY010000007        65733 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.007, whole genome shotgun sequence.
ACCESSION   DAXLPY010000007 DAXLPY010000000
VERSION     DAXLPY010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.007"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(14..211)
                     /locus_tag="ACF3UF_000512"
     CDS             complement(14..211)
                     /locus_tag="ACF3UF_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670667.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            380..958
                     /locus_tag="ACF3UF_000513"
     CDS             380..958
                     /locus_tag="ACF3UF_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFD3670668.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            1053..1190
                     /locus_tag="ACF3UF_000514"
     CDS             1053..1190
                     /locus_tag="ACF3UF_000514"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670669.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(2003..2506)
                     /locus_tag="ACF3UF_000515"
     CDS             complement(2003..2506)
                     /locus_tag="ACF3UF_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3670670.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            2865..3890
                     /locus_tag="ACF3UF_000516"
     CDS             2865..3890
                     /locus_tag="ACF3UF_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFD3670671.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            4213..5091
                     /locus_tag="ACF3UF_000517"
     CDS             4213..5091
                     /locus_tag="ACF3UF_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFD3670672.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            5567..5683
                     /locus_tag="ACF3UF_000518"
     CDS             5567..5683
                     /locus_tag="ACF3UF_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFD3670673.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            6611..6949
                     /locus_tag="ACF3UF_000519"
     CDS             6611..6949
                     /locus_tag="ACF3UF_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670674.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            7043..7273
                     /locus_tag="ACF3UF_000520"
     CDS             7043..7273
                     /locus_tag="ACF3UF_000520"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFD3670675.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            7673..8044
                     /locus_tag="ACF3UF_000521"
     CDS             7673..8044
                     /locus_tag="ACF3UF_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFD3670676.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(8318..9010)
                     /locus_tag="ACF3UF_000522"
     CDS             complement(8318..9010)
                     /locus_tag="ACF3UF_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3670677.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(9013..9798)
                     /locus_tag="ACF3UF_000523"
     CDS             complement(9013..9798)
                     /locus_tag="ACF3UF_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3670678.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            10035..11435
                     /gene="lacG"
                     /locus_tag="ACF3UF_000524"
     CDS             10035..11435
                     /gene="lacG"
                     /locus_tag="ACF3UF_000524"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFD3670679.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            11460..11777
                     /locus_tag="ACF3UF_000525"
     CDS             11460..11777
                     /locus_tag="ACF3UF_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3670680.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            11790..13463
                     /locus_tag="ACF3UF_000526"
     CDS             11790..13463
                     /locus_tag="ACF3UF_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFD3670681.1"
                     /translation="MDGIIKQIEKGKAFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            13477..15108
                     /locus_tag="ACF3UF_000527"
     CDS             13477..15108
                     /locus_tag="ACF3UF_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFD3670682.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(15599..17164)
                     /gene="guaA"
                     /locus_tag="ACF3UF_000528"
     CDS             complement(15599..17164)
                     /gene="guaA"
                     /locus_tag="ACF3UF_000528"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFD3670683.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(17223..18146)
                     /gene="coaA"
                     /locus_tag="ACF3UF_000529"
     CDS             complement(17223..18146)
                     /gene="coaA"
                     /locus_tag="ACF3UF_000529"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFD3670684.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            18342..18947
                     /locus_tag="ACF3UF_000530"
     CDS             18342..18947
                     /locus_tag="ACF3UF_000530"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3670685.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            19255..20271
                     /locus_tag="ACF3UF_000531"
     CDS             19255..20271
                     /locus_tag="ACF3UF_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3670686.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            20412..21713
                     /locus_tag="ACF3UF_000532"
     CDS             20412..21713
                     /locus_tag="ACF3UF_000532"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFD3670687.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            21759..22421
                     /gene="deoC"
                     /locus_tag="ACF3UF_000533"
     CDS             21759..22421
                     /gene="deoC"
                     /locus_tag="ACF3UF_000533"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFD3670688.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            22442..22840
                     /locus_tag="ACF3UF_000534"
     CDS             22442..22840
                     /locus_tag="ACF3UF_000534"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFD3670689.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            22906..23988
                     /locus_tag="ACF3UF_000535"
     CDS             22906..23988
                     /locus_tag="ACF3UF_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3670690.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            24200..25762
                     /locus_tag="ACF3UF_000536"
     CDS             24200..25762
                     /locus_tag="ACF3UF_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670691.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            25755..26888
                     /locus_tag="ACF3UF_000537"
     CDS             25755..26888
                     /locus_tag="ACF3UF_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3670692.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            26888..27844
                     /locus_tag="ACF3UF_000538"
     CDS             26888..27844
                     /locus_tag="ACF3UF_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3670693.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            27943..29109
                     /gene="deoB"
                     /locus_tag="ACF3UF_000539"
     CDS             27943..29109
                     /gene="deoB"
                     /locus_tag="ACF3UF_000539"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFD3670694.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            29133..29951
                     /locus_tag="ACF3UF_000540"
     CDS             29133..29951
                     /locus_tag="ACF3UF_000540"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFD3670695.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            29968..30675
                     /gene="deoD"
                     /locus_tag="ACF3UF_000541"
     CDS             29968..30675
                     /gene="deoD"
                     /locus_tag="ACF3UF_000541"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFD3670696.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(30973..31659)
                     /gene="gpmA"
                     /locus_tag="ACF3UF_000542"
     CDS             complement(30973..31659)
                     /gene="gpmA"
                     /locus_tag="ACF3UF_000542"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFD3670697.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(31831..32412)
                     /locus_tag="ACF3UF_000543"
     CDS             complement(31831..32412)
                     /locus_tag="ACF3UF_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3670698.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(32545..33228)
                     /gene="rpiA"
                     /locus_tag="ACF3UF_000544"
     CDS             complement(32545..33228)
                     /gene="rpiA"
                     /locus_tag="ACF3UF_000544"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFD3670699.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            33547..33960
                     /gene="rpsL"
                     /locus_tag="ACF3UF_000545"
     CDS             33547..33960
                     /gene="rpsL"
                     /locus_tag="ACF3UF_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFD3670700.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            34044..34514
                     /gene="rpsG"
                     /locus_tag="ACF3UF_000546"
     CDS             34044..34514
                     /gene="rpsG"
                     /locus_tag="ACF3UF_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFD3670701.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            34608..36695
                     /gene="fusA"
                     /locus_tag="ACF3UF_000547"
     CDS             34608..36695
                     /gene="fusA"
                     /locus_tag="ACF3UF_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFD3670702.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            36867..38054
                     /gene="tuf"
                     /locus_tag="ACF3UF_000548"
     CDS             36867..38054
                     /gene="tuf"
                     /locus_tag="ACF3UF_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFD3670703.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            38461..38769
                     /gene="rpsJ"
                     /locus_tag="ACF3UF_000549"
     CDS             38461..38769
                     /gene="rpsJ"
                     /locus_tag="ACF3UF_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFD3670704.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            38800..39429
                     /gene="rplC"
                     /locus_tag="ACF3UF_000550"
     CDS             38800..39429
                     /gene="rplC"
                     /locus_tag="ACF3UF_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFD3670705.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            39457..40080
                     /gene="rplD"
                     /locus_tag="ACF3UF_000551"
     CDS             39457..40080
                     /gene="rplD"
                     /locus_tag="ACF3UF_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFD3670706.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            40080..40370
                     /gene="rplW"
                     /locus_tag="ACF3UF_000552"
     CDS             40080..40370
                     /gene="rplW"
                     /locus_tag="ACF3UF_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFD3670707.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            40409..41242
                     /gene="rplB"
                     /locus_tag="ACF3UF_000553"
     CDS             40409..41242
                     /gene="rplB"
                     /locus_tag="ACF3UF_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFD3670708.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            41285..41563
                     /gene="rpsS"
                     /locus_tag="ACF3UF_000554"
     CDS             41285..41563
                     /gene="rpsS"
                     /locus_tag="ACF3UF_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFD3670709.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            41586..41933
                     /gene="rplV"
                     /locus_tag="ACF3UF_000555"
     CDS             41586..41933
                     /gene="rplV"
                     /locus_tag="ACF3UF_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFD3670710.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            41947..42603
                     /gene="rpsC"
                     /locus_tag="ACF3UF_000556"
     CDS             41947..42603
                     /gene="rpsC"
                     /locus_tag="ACF3UF_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFD3670711.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            42606..43040
                     /gene="rplP"
                     /locus_tag="ACF3UF_000557"
     CDS             42606..43040
                     /gene="rplP"
                     /locus_tag="ACF3UF_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFD3670712.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            43030..43218
                     /gene="rpmC"
                     /locus_tag="ACF3UF_000558"
     CDS             43030..43218
                     /gene="rpmC"
                     /locus_tag="ACF3UF_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFD3670713.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            43243..43509
                     /gene="rpsQ"
                     /locus_tag="ACF3UF_000559"
     CDS             43243..43509
                     /gene="rpsQ"
                     /locus_tag="ACF3UF_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFD3670714.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            43567..43935
                     /gene="rplN"
                     /locus_tag="ACF3UF_000560"
     CDS             43567..43935
                     /gene="rplN"
                     /locus_tag="ACF3UF_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFD3670715.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            43972..44280
                     /gene="rplX"
                     /locus_tag="ACF3UF_000561"
     CDS             43972..44280
                     /gene="rplX"
                     /locus_tag="ACF3UF_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFD3670716.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            44308..44847
                     /gene="rplE"
                     /locus_tag="ACF3UF_000562"
     CDS             44308..44847
                     /gene="rplE"
                     /locus_tag="ACF3UF_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFD3670717.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            44866..45051
                     /locus_tag="ACF3UF_000563"
     CDS             44866..45051
                     /locus_tag="ACF3UF_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFD3670718.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            45087..45485
                     /gene="rpsH"
                     /locus_tag="ACF3UF_000564"
     CDS             45087..45485
                     /gene="rpsH"
                     /locus_tag="ACF3UF_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFD3670719.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            45517..46053
                     /gene="rplF"
                     /locus_tag="ACF3UF_000565"
     CDS             45517..46053
                     /gene="rplF"
                     /locus_tag="ACF3UF_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFD3670720.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            46214..46570
                     /gene="rplR"
                     /locus_tag="ACF3UF_000566"
     CDS             46214..46570
                     /gene="rplR"
                     /locus_tag="ACF3UF_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFD3670721.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            46591..47091
                     /gene="rpsE"
                     /locus_tag="ACF3UF_000567"
     CDS             46591..47091
                     /gene="rpsE"
                     /locus_tag="ACF3UF_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFD3670722.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            47106..47285
                     /gene="rpmD"
                     /locus_tag="ACF3UF_000568"
     CDS             47106..47285
                     /gene="rpmD"
                     /locus_tag="ACF3UF_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFD3670723.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            47329..47769
                     /gene="rplO"
                     /locus_tag="ACF3UF_000569"
     CDS             47329..47769
                     /gene="rplO"
                     /locus_tag="ACF3UF_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFD3670724.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            47769..49064
                     /gene="secY"
                     /locus_tag="ACF3UF_000570"
     CDS             47769..49064
                     /gene="secY"
                     /locus_tag="ACF3UF_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFD3670725.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            49126..49773
                     /locus_tag="ACF3UF_000571"
     CDS             49126..49773
                     /locus_tag="ACF3UF_000571"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFD3670726.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            49964..50182
                     /gene="infA"
                     /locus_tag="ACF3UF_000572"
     CDS             49964..50182
                     /gene="infA"
                     /locus_tag="ACF3UF_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFD3670727.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            50215..50331
                     /gene="rpmJ"
                     /locus_tag="ACF3UF_000573"
     CDS             50215..50331
                     /gene="rpmJ"
                     /locus_tag="ACF3UF_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFD3670728.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            50349..50714
                     /gene="rpsM"
                     /locus_tag="ACF3UF_000574"
     CDS             50349..50714
                     /gene="rpsM"
                     /locus_tag="ACF3UF_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFD3670729.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            50742..51131
                     /gene="rpsK"
                     /locus_tag="ACF3UF_000575"
     CDS             50742..51131
                     /gene="rpsK"
                     /locus_tag="ACF3UF_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFD3670730.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            51211..52149
                     /locus_tag="ACF3UF_000576"
     CDS             51211..52149
                     /locus_tag="ACF3UF_000576"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFD3670731.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            52177..52557
                     /gene="rplQ"
                     /locus_tag="ACF3UF_000577"
     CDS             52177..52557
                     /gene="rplQ"
                     /locus_tag="ACF3UF_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFD3670732.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            52829..53668
                     /locus_tag="ACF3UF_000578"
     CDS             52829..53668
                     /locus_tag="ACF3UF_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3670733.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            53644..54513
                     /locus_tag="ACF3UF_000579"
     CDS             53644..54513
                     /locus_tag="ACF3UF_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3670734.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            54503..55300
                     /locus_tag="ACF3UF_000580"
     CDS             54503..55300
                     /locus_tag="ACF3UF_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFD3670735.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            55503..56249
                     /gene="truA"
                     /locus_tag="ACF3UF_000581"
     CDS             55503..56249
                     /gene="truA"
                     /locus_tag="ACF3UF_000581"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFD3670736.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(56704..59373)
                     /locus_tag="ACF3UF_000582"
     CDS             complement(56704..59373)
                     /locus_tag="ACF3UF_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFD3670737.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(59611..59799)
                     /gene="rpmB"
                     /locus_tag="ACF3UF_000583"
     CDS             complement(59611..59799)
                     /gene="rpmB"
                     /locus_tag="ACF3UF_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFD3670738.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            60069..60431
                     /locus_tag="ACF3UF_000584"
     CDS             60069..60431
                     /locus_tag="ACF3UF_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3670739.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            60483..62165
                     /locus_tag="ACF3UF_000585"
     CDS             60483..62165
                     /locus_tag="ACF3UF_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFD3670740.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            62282..64318
                     /gene="recG"
                     /locus_tag="ACF3UF_000586"
     CDS             62282..64318
                     /gene="recG"
                     /locus_tag="ACF3UF_000586"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFD3670741.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            64367..65368
                     /gene="plsX"
                     /locus_tag="ACF3UF_000587"
     CDS             64367..65368
                     /gene="plsX"
                     /locus_tag="ACF3UF_000587"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFD3670742.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            65490..65732
                     /gene="acpP"
                     /locus_tag="ACF3UF_000588"
     CDS             65490..65732
                     /gene="acpP"
                     /locus_tag="ACF3UF_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFD3670743.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
BASE COUNT        21118 a        11741 c        14109 g        18765 t
ORIGIN      
        1 atggtatcat acattaataa tagttttttc tatgtgtatt tcctttgatc cagcgaacaa
       61 gccagatgat aagtgcgatt gggattagaa ctttgaccgc aaaccataaa agcccgctta
      121 ggacactgac aaaaagactg atgacgaagc tagctgcaat tagcactaaa agaaccatga
      181 agatatttaa gaacatattt ttttgacgca tacaaaaccc tcctcttgtt cattctttac
      241 tatagaaaaa gtataacagg gattgtttaa aaacacctcc aactgaagac tgatttttac
      301 ttcatctact taaatgatca aacaattgct ttttctctgg tttatcatct aaaatagagc
      361 ggaaaaggag gagaatatca tgcctaaaaa tcgtcttgaa gcatttacag atgctgtaat
      421 cgcgattatc atgactattt tagttttaga acttcatgaa cctaacggag acacgtggga
      481 ggcgctcgct gcattaggtt accgattttt tatctatatt gtcagtttta tcattttagc
      541 gatttattgg aacaatcatc atcatttatt tcaagttgta cataagataa atggacgggt
      601 cttatgggcg aacagtttct ttgtttttgc gctttcgctt tttccgtttg caacttcatg
      661 gatcagtgag tacatcaata gcctggctcc agaaatgact tatggttttg ttaccttgac
      721 cgctaatatt gcgtattata tcttggcaaa agaacttgtc aaagcaaata aaggccacga
      781 gaaagcattg aaggcgatgt tgaataatta caagaaatcg tatctatcga ttggtttgaa
      841 tgtgttagga attgtcttag ggtatttagt agcgccagta gccgtgctga tcgcaaacat
      901 cgtgattcta gctgcttgga tcatcccaag tcgtaccatc gaatcacaat atcggtaaaa
      961 tgatccgtgt ttaaaattta agagaaaaat atagaaaaaa taaataaacg atcaaatatc
     1021 cgagtgatac tagtattcaa agagggatgc agatggatca aaaaagaatt catgtaggac
     1081 tgattactag ttttgtcacg atgcttattt atttggatca aggtcatttg acttggacag
     1141 tagttggtgt cgtaggattt ttgacattat tcacagcaat aaaaaaataa acatctttat
     1201 gtaatctgat gttctatcta tttaagaaaa gcatgtttac agcagtatga ttctgttgta
     1261 aacgtgtttt tatttgtgga aaatttaatt tttagaaaag tgtatcgaaa aatagatagt
     1321 tagtttttcc acagtggata acttcgtaag agataaaaat aaaaaattag tcaaagaagg
     1381 gcgtatagat ttcttttgat aggagatata caacagaaat gaataaatat taacgtgttt
     1441 tcaaacagta taaaacggtg tggtttttgg aataaaaaaa taacatatct cattttacac
     1501 ttttgttatt ttatacttaa aaaataacga cacagaaaat accgtgtctc agatttctct
     1561 actacttcta aaaactactg tttttttcct ttgaaatgcc ttcaaaaagt aggatcaggc
     1621 agaatatact ggcagaatca aggagaaggg agcctaaata aggagaaaaa ccatagaaaa
     1681 tataaagtaa ttacttataa aacaagcttt ttatagaaaa ataatatacc tgagtagggt
     1741 ataaattaag acggaattcc tttctagatt gagatattga ctaggaagaa tgttaagatt
     1801 ttaagccttt aagctaaaaa aaaacccttt ttgttaaata aggggaatat agcctgtcag
     1861 tttcaaactg caagtcgtcc tgctgcaata atatagtaga ttagagatga aaatagattt
     1921 ttttaaacca atgactgaat aaaaagaccg tcatagatac acattggaat gtgtctatta
     1981 cggtcttttt ttacgaacga ttttattgaa gacggacagt tcgggtcaaa aataaaaaag
     2041 ctacgatcag aaataagaat aaaatgtatc ccaaaataat ggctagacgg tctaacttat
     2101 ttgtcgatag atgtttgttt agaagttgat aggcccataa acctatcagt cctcctgttg
     2161 tattagttat caaatcagtg atgtccgcta cgccaatacc gaataggaat tgaatcaatt
     2221 ctgccaagaa gcttacaagg aaaataatcc ctaatttttt agaaaaagaa agtctcttga
     2281 aattgacatt caaaagcacc ccaaaaggaa aaaagacaat caagttataa gtggtctcac
     2341 gtaataccgt cgtattttca aaagaaaaag tagaaaaagg gacgagattg acattgctgt
     2401 aagaataagt gagaaattgt ggaagattaa atgatagctt gaataaaatc aaccataata
     2461 gaaagaataa ataaatccct aataaaaatt ttgatacata ccgcatagac atctcctcca
     2521 tttaaaaagt ataccatcga aaaccgctga aaaatcataa aaaagtatga agtttaagga
     2581 ccaacgtagt tatcgtacga aaattagaag cttttttttg ttgggaatcc ggtttcttta
     2641 acaaagctaa gatagcgagt tgcttggaaa agttgctatc ttttttctgt caaaacgact
     2701 cggaatgttc gttttttgtt ctaatttctc caagttgttt actttttgat actaagttta
     2761 tgaaaaatca agaaatagtt gttatactag gtaatgctga caaacgggat tggcatttca
     2821 tcttggttca gctttttttc caattactag gaaggaggga tagattgttc aagacttatt
     2881 ttcgtttcaa taaaatacaa gataatcctt ttcgtatcat gaatctgatg ctacttatct
     2941 ttattgtatt atggttaggt tacataaatc atgatttttt gatttcaagt ttttcatcat
     3001 tagggatctt tacttttttc tattatcaaa acataccgat gaaatatttg ctgaaacgta
     3061 tgtttctgat cggttgcgga ctgttggttg ctttcgtttt ggggatctta tcgacttatg
     3121 ttttatggct tgaaccattt gccgtagctt tggttgcttt ttccagcaga ttcgtgttgc
     3181 gattattcca tatttctaaa ccaggtggct tgttttttgc gatgctttct gccatgggaa
     3241 cgagcatgca gctgccaatc gctcaattac cgatcgtctc actttatttt tttatgggtg
     3301 tcgtttttgc cctgattgcg gcagtgatta caaaattact ggattcacgg cctgagcaga
     3361 caattgaaaa agcaacttta aaagaaagat ttcacgaaga gcctttagtg atcattgatt
     3421 ctgttttcta cagcgctgcc ttatttcttt ccgtttatgt cagtcacggc ttgaatctgc
     3481 ataatcctta ttggttgacc ttgtcatgtg catcgatttt gctagcagaa aacttggatg
     3541 cgatgaagca tcgacaagtc caatatctga ttggatcgat gggtgggtta tgtgtgtcgg
     3601 cattcttgtc atttgtgccg tttacgcagt tgcagaccat ttttctgatc acttttctat
     3661 atggaatcgc acaatttcta gttgctagaa attatgcagt tgctaatatt tttcttaatc
     3721 cgatggcgtt gatgctatct acacttattc gtggagcata cttgatttct ttgatcgaat
     3781 atcgtttttt agggatcgtc ataggaagtt tcatcggttt aggtgttgcg tgggtaatga
     3841 cggttggttt gcaacattat ttaacggttg ttcgtcaaaa attagaatag aaggacaaat
     3901 atatgtgcca aaagaggtta tgacaagatt tttgtcacaa cctctaattc aaggtgttca
     3961 aaagccagat tctcagcatt aagtcaaatt cacacaaaaa tgtggaaagg aactttcaaa
     4021 aaaattttat atttattcta tcaaaaaatt ttgtttatga tggtaactga ataaactttc
     4081 ctgagatggt caatgctttc cttgaaagtc ttacagatat tctttcttca tagaaagttt
     4141 aagttttata gttagtgtac aataaaagta tgtttatacc atatggtgtc cggataatca
     4201 gtcatttaaa caatgaggtt caaagatatg aaaaggggaa atttgatgaa gaaaataagc
     4261 aatgaaatcc aaattctggc agaaacttta actcttccca aagtcgttat agagcaaatg
     4321 attgtacaag caaaaaacat ccttgatgag gtgtttgagc aatatagtca tgaactaatg
     4381 gatcctaata aagcaaaggc gactgcaaag aaaatagaca aagtctatga agaggaacct
     4441 tttgcagcat tagctattta tctatatgca gcttctcaaa gttggaaaaa aatttatcaa
     4501 ccattgaaga ttccaagaac tatctatttg gcaacaatga atgcttttac tagatttatt
     4561 catgaacatt tccaagtaac aggaagctat cgctttgacc gtggtttttg gatttggcat
     4621 tacactagtg gcttgatctt tcggattggt gaattggagt acgaaatgac atattttccg
     4681 aaagggtaca cggatctaag attagaagga aagcagtgcc tttctcttca tattccttcc
     4741 gatgcagatt tatctcagaa taagataaga gatagttacg aaagtgccat tcgttttttt
     4801 gaactttatt ttcctgatta ccattaccaa gtgatgtaca cagatacttg gttactatca
     4861 cccaatctta ctaaatggtt gaaaaaagag tcaaaaatct gtctttttgc agccgattat
     4921 cgattattat cagttgatga acaggacgat agtggagtcc cttggatctt tggacgagta
     4981 gatgcccaaa tacatgatta tccagaaagt acgagtttac agcgacaagc aaaagagcaa
     5041 ttgcttgcag gcgagcacat tggctctggc ttaggtattc ttacttcata agtttagtac
     5101 ttcgaaatag tttaaaagag cgtgagacaa aagtaaagaa cacttttgtc tcacgctcta
     5161 aacacgtata aacggcggaa gcagaagcaa ctccttcgga aataagctga aattcacaaa
     5221 aatttgaaaa gcaattttcg tgaatttctt cttgtttctt ggagttaaac gcttctgtcc
     5281 cagcctcttt tttagtgttc tatcgaacac acagtacgtt caataggtaa actagctata
     5341 acaatagata ttaaagttaa cggacaagag ggcctttttt aggtagctaa aacgtaataa
     5401 tgaaaattta tttccagaga taggagtcaa tcagctagtc tgatcgactg ttttaacaag
     5461 ttgactttca ttttaacttt tgataccatt taaaacacaa atcgtaattg tttcgatttg
     5521 tgttttttag catgactaca atcaaagaag aaagtgggtc gtccatatgg aaaaaacaga
     5581 tatctcaagt gcataccgcc gcttgaaaag cccaaatatc aaaacacgaa aacgtgcgct
     5641 gaagatcatc aaagatgtga aacggaatag tgggaaaagg taagaagaag gaaacttaat
     5701 taaaaaaata gccgaaaaac gtttttcggc tattttcaat aatcggtttt tgtgtaaggt
     5761 ttccgaaaga actgctgttg attttccatt tttaacatat gataaattgg tagaatcttt
     5821 cttttcaaat tgataccatt ccctaattcc agttatatag ttaactacag aaccacaaag
     5881 cacgtacgtt tataaaagta ttatctgtag ttatttttca attccctttc aacctcttat
     5941 tttgaccagt agtattgatc actttacctt ttaacacctt tgttcgtttt tgaaacattt
     6001 ttagtcaaga atggaaacgt aactacataa tcaaaggttt tgcgaaatat ttcatgaaat
     6061 atttcatgta gaagcgagca atacggttgc aaataaccat tatcgtttaa taagcagtta
     6121 cgaaagctcc caatatctct aacgttcagc tcactccatt tcttttcttc aaaaaaatca
     6181 gtgattcgta tctctttcta tttgtcgaaa aagttaactt taaaaagtaa cgccgaaaaa
     6241 atatgcaaaa aaataaaaaa gcagttacta ttgctagaat aacatcaagg aataataagt
     6301 tttggttttc agataatagt cgataagttg tgtattggaa ttttagatac agtaataaag
     6361 tatttttcat gaaattttgt gagaatcact attacaagta tctttaataa aattaatggt
     6421 taaggaggaa cttaaagtag aatgtaaatg aatagttgta gtcagtcgat tgtgatacta
     6481 gactcaaagt tgcaggaata agtttttcaa tttgtgattg gaagataaaa aatgaaaaag
     6541 aagggctttt ttttatactt tgttgattgt agtgtttatt ttccctctgt ttagccaagt
     6601 aacattttct atgactcaac cagtttcaag tgaggaacat gataaccttt ttcgtgctac
     6661 agaagagttt aagaaatatc aggaaaatat tgttccggag actccattag ctagtgagcc
     6721 aattactgat attgatggaa accaaatagg atggtatata cagtacgaag ttatggtggt
     6781 aaataatgac tcaatagtaa aaaatacagt aggcttagag ctaacaccga ttgaaaaggt
     6841 gagttcattg ttaacgtata tttatactga tgaaagtgac gagactgaga tcattttaac
     6901 ggattactca aaaattgcta ctgataaaaa gtatatattg tggatgtaga cactagtgaa
     6961 atactttatg atatagaaat tgatgaaaat ttactagatg tagcacaaga aatcgatcat
     7021 caaaagcagg aagctattcg atatgctggt agaaaaggga aaagaaaata tttattacgt
     7081 gaatgtagca aaagttagag aagatgaaaa tgagtggaaa gaattcaaga gtcgctactc
     7141 aattaactcg actccgacat ttacagttta cagagaagga tcgatagaaa aaactgtttt
     7201 ttggactaaa gaaagtggaa tgtctttagc tgaagtagaa gagtttttgg attatgttag
     7261 tatgcaacag taagggagtt cttattatga aaaattttga cacatattat gttattgttt
     7321 tttcgatatc tttgctgtta atattactaa ctttaatgca gtataaagag tatccagagt
     7381 attttatttt aacttttgta tatttagtaa gtagctacac acttctatat aaattcagaa
     7441 gttcttctag agtttctaaa gtttgtttct taattagctt attgattcta taatattttt
     7501 gatttatata ggaaattaaa aatattatag aatcaacact cagagaacgg gttggttttt
     7561 aatagattta ataagtactg ataatgaaat ttctcctggt tgggaaaacg aagttggtta
     7621 ccctgtagaa gaattttttc aagattactt tgcggagtat gccgatagga taatgagaga
     7681 ttacgtaaca gataaaactc aagaagtcat caatcaatcc cagtcattaa atgaattatc
     7741 tgataaggcg aaagaagaag cagttgccat tatttcttca gggattagtg actatattga
     7801 tatgagtggt gaaatcaatt atggcgataa agacaaaatt gtacgcatga taaaagcttt
     7861 tatcaaaact tttgatgtga aggcagatct taagtttaat gatacttacc tagtaggaaa
     7921 attaattaat atccttggga cagagaaaga tacggaaacg tttatttcct ctttgtctat
     7981 gttgtttaca gataagcatt tttcaactca gcttggtgga gaggaactag tggaaatctt
     8041 ttaaccatta cgcccagcat taataaaagt atatcaaaaa agtactcctg atgattttta
     8101 agattggttt gagaaataat gtgaaaacac tatttttaat gttaattata gatagagatg
     8161 aacgcgtcat atggttaaaa gaatgaaaaa gtcaaagata cactgctata tttcactaag
     8221 gatatagcag tgtatctttc atgtcgtttc actggcagtt ttttataaaa ggaggtgtgc
     8281 atttcagttg cttttctttg gtagttagtt gaatcgttta agaattaacg gatgtggcag
     8341 acaggtgctc tgtccaaaaa ccagtaaaat ctttgatggt tccatcttta tttagctgtg
     8401 cctgttcaaa tactgttttg tttttaccga atggatcaat tgcaataatt gttccgatcc
     8461 ccgcacgttt ggcagcaagt aatcctgagt aagcatcttc gataacaaga caatcagccg
     8521 gagctaagct cagtttgtct gccgctttaa gaaaaatatc cggttgcggt ttcccaggga
     8581 aagagccgtc gtcatagaca atcttgtccc agtcaaacca gcgggctaaa tcgaaaatat
     8641 caaaataaaa agcaacattc tctttgacag tagccgtggc aatcgttaat ggaatctgtt
     8701 ggtcagtcag ctggtcaaga gtcgcttcaa gcccttttgt caactgaagc tcgttttcat
     8761 tttgcaagca aagcatacga taatagcttt ctttttcttc tgacaatacg gcgatctcag
     8821 aggcggtcaa atgctctgaa atgaaatgtt tcaaaatctc cgtattcgtc cgaccatgaa
     8881 tattttttaa aatatcctcg tctgataaac catcttttgt atgatcatgt atcatatgca
     8941 gccaagcagc ttcatgcaga tgagagtcca aaaacattgt tccgttgaaa tcaaatataa
     9001 tccctttcat agttacgctc ctatagtggt attttcggtt gaatcagcaa tttgcagatc
     9061 gacatattgt gcatagtgct cttgaacctc ccgcgagatc tggcgatccg taatgagcag
     9121 atcgaaatca tgcaaattat aaaacacata aaaatcatct cgattgaatt ttttattatc
     9181 aacgagtaga tatttcttac gggaattatt tagagcgatc tgctgtgctt ctccttcttc
     9241 ggtactgtaa gtagagatcg cttcgttgtg aacgccattt gaactgataa atgcttttgt
     9301 aaactttagt cttcttaaat tgtcgttggt gatcggtccg acaaatgcgc cggtattttt
     9361 ccggaaatca ccgccaatca gtagaatttc tggtccatct gcttgagcaa gaatatcaaa
     9421 aactggataa ttatttgtaa tgatccgaat tttcttgttc agtaaatgcg tcgccaatag
     9481 ttcgattgtt gtacctggtc ctaagaaaat cgtttctccc tcgtgaatca aggaggctgc
     9541 tgtggcagca atttcttttt tttcttgaat ctgcagagtg gctttttcag tgtgagaaag
     9601 ttcttgatct aaagtgtagg aaagactttg agcccctcca tggacacgca gcagcttgcc
     9661 cgatttttct aattcatcta aatctctgcg aacggtcata tcagaaacat ctaattgatt
     9721 gatgatttca ttaacggtaa ggattccttt tttattgacc atttctacga tagtaagcaa
     9781 tctttctttt ttcaacattg tcttcacctc taatttaagg ataatctatc atataaacgg
     9841 acaacagtca atctaattcg aacaaaagta aacatttagg gtggttttta tgtttgttac
     9901 aatagatttt attgctgttt tctggttttt atgattattt gtgtttgttt ttgttgacaa
     9961 atgttttgga tgcgtttaca atgcaatcag ttagaaagag cgaaaactga ttatagattt
    10021 gaggagagat gtacatgctt aaattaccag aagattttat ttttggcgga gccacagcag
    10081 cctatcaggt tgaaggagcc actaaggaag gtggcaaagg cgctgttgct tgggatgact
    10141 ttttagagga acaagggcga ttcagtcccg atccggcaag tgatttttat catcaatatg
    10201 caaaggacat tgaattgtgt gaacgttttg gtgtaaatgg tctaagatta tccattgctt
    10261 ggagccgcat ttttcctgat ggagctggga aaccaaatcc agaaggaatc gctttttatc
    10321 atcgtgtgtt cgaagaatgt aagaaaagaa acgtaacgcc gtttgtgacg ttgcatcatt
    10381 ttgatacccc taaacgtttg tttgaccatg gagatttttt gaatcgagaa acaatagaag
    10441 catttgtttc ctatgccatt ttttgttttc atgaattcaa agaagtcaag gtgtggagta
    10501 cctttaatga aatctatcca gttgcaacca atcaatattt gttaggtgtt ttcccaccag
    10561 gaatcaaata tgattttaca aagatcgtcg cctgtcttca taatatgatg gttgctcatg
    10621 cccgtgtagt gaactatttc aaagaaaacg aacttccggg tgaaattggt gtagttcact
    10681 cattagagac gaaatatgcg gcaacagacg cgccggaaga taagcatgct gcctttttag
    10741 acgatgcatt gtcgatccgt ttcttattag atgctaccta tttaggctat tattcaactg
    10801 aaaccttgac tgctcttgat gagatatgtg aagcaaatca ggccagctat cattttcctg
    10861 aagaagattt cgttgaattg aaaaaagcat ccacgcgtaa tgactactta gggatcaatc
    10921 actaccaatg ccattttgtc aaagcttacg atggagaaaa tgcaatccat cataacggta
    10981 cgggtgaaaa agggacctct gtttataaag tgaagggaat cggagaacgt atttataaag
    11041 aaggaattcc tcgaactgat tgggactggc tgatttatcc agaaggtcta tatgacttgt
    11101 tgctgcgaat taaaagcgat tacccacatt acaacaaaat ctatatcact gagaacggga
    11161 tggggtataa agatcagttt gaagatggca ttattatgga tcagccgaga atcgactatt
    11221 tgagagtcta tttggaatcc ttaagcaagg cgataacagc cggggtaaat gtgaaggggt
    11281 attttttgtg gtcgcttatg gatcttttct catggacaaa tgggtataac aaaaggtatg
    11341 gcttgtttta tgttgatttt gaaacccaga agcgttaccc aaaagaatca gcttactggt
    11401 acaagttggt cagtgaaacc aaaacgatta tttaataagt gataatggag gaagaaaaga
    11461 tgaataaaga ggaattacaa atgcttggtt ttgagatcgt tgcatattca ggcgacgctc
    11521 gcagtacatt attgaaatta ttgaaagaag taagacaagg aaactttgaa catgttgatt
    11581 cggcgttgaa agaagccgac gaaaatttaa cccttgcaca taattcgcaa acaaaaattt
    11641 tagcggaaga agcatctggg aaagagatgg agatgggatt catttttatc catgggcagg
    11701 atcatttaat gaccacttta ttgctgagag atctgattca agactttatt gtactgtaca
    11761 gacagaatca aggataggag aagaacgcta tggatggaat cattaaacaa atcgaaaaag
    11821 ggaaagcatt ttttgaaaaa atctcacgta atagttattt aggagccgtt cgtgacggat
    11881 ttttaacagc gatgccagct attttatttt caagcatttt cattttgatt gctgcggttc
    11941 ctgagatttt tggttaccaa tggcctgaat ctgtctccac atggctatgg aaagtctata
    12001 attattcgat gggtgttgta gggttactcg tttcagcaac cactgctcgc tgcttggctg
    12061 attcgatgaa tcgtcgctta ccgaaaaaca aagtaatcaa caccacctct gtgatgctgg
    12121 cctctgtggt aagtttcctg ttgttaagcg tctctccgat tgaaggtgga ttttcaacgg
    12181 aatatatggg gacaaaggga ctactggctt cctttgtcgc tgcattttta acagttaatt
    12241 tatataagtt ttgtgtgctg aaagatatta ccattaaaat gcctaaagaa gttcctggaa
    12301 cgatttcgca aaccttccga gatatttttc ctttctcttt ttcagtattt gcggccgttt
    12361 taattgattt aggcattcga caaatcttcc aaatctcatt tgcagaagca atcattacgg
    12421 tgctgcagcc gctatttaca gcagctgacg ggtacttagg aatcgctatt atctggggag
    12481 cgatggcgct gttttggttt gtcggtgttc atggaccgtc gatcgtggag ccggcaattg
    12541 cggcaattat ctatgccaat gtggaaacca atctgcaatt gttcaattcc ggtgaacaag
    12601 cttctaaagt actgacggtg ggtttaggga attttgtagg aactatggga ggaactgggg
    12661 caacattggt tgttcctttt atcttcctac tctttgctaa gtctaagcag ttgaaggcag
    12721 ttgggaaagc ttcctttatt ccagtaagtt tcgctgtcaa cgaaccattg ctatttgcgg
    12781 cacccatgat tttgaaccct tattttttta ttccattttt gttaacacct gttgtaaacg
    12841 tttgcctgtt caagtttttt gtcgatgtat tgggcatgaa cagctttatg tacgttttgc
    12901 cttgggcaac tccagcaccg atcggtttgg ttctaggaac gggcatgggt atcttagctt
    12961 ttgttctagc agcggttcta atcgtcgttg acttcctgat ctatctacca ttttgcaaag
    13021 catacgatgc tgtcttagta gagaaagaag cacaaaaagc agaggtgatc gcaaccgagg
    13081 aaggtgcttc tgccgatgta cgtgaggaag tacctgtggc agcgagtcaa gttatcagcg
    13141 atgcaaataa agaaatcaat gtgttggtac tttgtgctgg cgcagggaca agtgcgatgt
    13201 tagctaatgc tttaaaaaaa ggtgcatctg aatcgaaagc accgatcagt gcaatggcgg
    13261 gtgcttatgg ttctcattac gaaatgctgc aggattttga tatggtggtc ttagcaccgc
    13321 aagtcaattc ttactatgat gatatcaaag aagacaccga tcgcttagga atcaagctgg
    13381 ttgcgacaaa aggagcagaa tatatcggat taacgagaga tcctgaaaaa gctgttcagt
    13441 ttattctgaa ccaatttcaa taaaggagga gccataatga aaatgggaat ttggttgcgt
    13501 aaagctgttt tatttgcagc tgtgttaggg gctttggggg ctgtttcaaa aactgttgaa
    13561 gcatctgcca gcgaatttat tcgcggagca gatatttcga tcctgtcaga tatggaaaaa
    13621 tctggtgcaa aatattatga agacgatatt tcaaaagatg ccttagagat tttaaaaaat
    13681 aatggtgtca actatgttcg actgcgtttg tggcaggatc cttataatag taatggagaa
    13741 agttatggag cagggacaaa tgatctggaa acgacgattg accttgcaaa acgagcaaaa
    13801 aatctgggac ttaaggtgct gctggatttt cactacagtg atttttgggt tgatcctggg
    13861 aaacagaatc ttcctaaagc atggcaaggt ctgacctttg aagaaatgaa tacggcattg
    13921 tacgactata caaagaacgt tctgtcggaa atgaagcagc tggacgttta tcctgatatg
    13981 gttcagatcg gcaatgaact gaatagcgga atgctctggc cttatggcaa gtcttgggga
    14041 gaaggcgggg gagaatttga tcgattggct gcttttttga agtctggtat ccaagctgtt
    14101 cgagacactc aacctaaaac aactccagta atgctccact tagctgatgg tggcgataca
    14161 ggagcattta cttggtggtt tgatgaaatc acgagtcgag gtgtgtcatt tgatttaatt
    14221 ggagtgtcgt attatccgta ttggcacggt tcaatgaatg aacttcaaac caatatgaat
    14281 gcgatcagcc aacggtatgg taaagaagtg atcgtagttg aaacagctta tgggcataca
    14341 acagcgaatg ccgatactat gccaaatgct tttggtgaag ccgaagcagc tgcgggggga
    14401 tatgaaccaa caccgacagg acaagcagag tatttgctgg atcttgccga tcggattcag
    14461 gcagtaccga ataatcgcgg ggcgggcttc ttctattggg aacctctttg gtacaacgga
    14521 aatgtgagtt gggcaacaca agcaggtatg aattatctca gtgttcaatc cactatggga
    14581 aacgaatggg acaaccaagc gatgtttgat tttgctggaa acgccttgcc aagcttgcgt
    14641 gcgtttaaac aagcaggggc gcaaataaat ctagttaaaa atgcaagttt cgaaagcgat
    14701 ggaccaacga ccagtccttc caattggcaa acctggtttc aacaaggaac cgctaagggt
    14761 acgatcaaaa cggaagcggg cacttttttt ggggactaca aactaacttt ttggcaggat
    14821 caagcatacg aggcatcagc ttatcaaaat gttagtggca taagcaaagg aacttacaca
    14881 ttgagtgcct atgtaatgtc tgggggagag tttgatacta atcagttata tatcaaaaat
    14941 tatggtggag cggaactaaa tactgcggtt gttaaaacaa gtgaatggac aaaaattaca
    15001 atcaaagaca ttccaattac aacaggtgtt tgtgaaattg gggtttatag caaggcttca
    15061 ggaaatgctt ggacgaacgt tgattttgtt tcattggtga aacaatagac tgcggatcgt
    15121 ttcgattcaa gatcggaggt tcccttcagc cacatcgtta gcgtagaagg caggaatcga
    15181 acctgcacct cgcctttgcc aaaaataacc agaaacgatt tccagtcatt tttaccaaaa
    15241 cgagtaaagc accagacttc atctacactt tgtattatgc taaagagagt tcaacgattt
    15301 cgtaagaagc aatgaaaaaa ttgcaaaaag ttgtgcagat aacataaagt ttgtttaaga
    15361 aagggtaacc ttagaattcc gtcgtgaata tgatttgagc acttagatgg atagaaaaaa
    15421 gttctcggaa aacagttcgt ttttcgagaa cttcttttta tgataagaat gaaacaaatt
    15481 aacttatatt atagtctctt ttggtaggga accatcttat ttttaatgaa aatcaagcat
    15541 tttagctatt gaagaatgtt gatttatagg gattccccct ccatattatg ttggctcttt
    15601 attcccactc cactgttgct ggtggtttag aagtgatgtc atacacgata cggttgacgt
    15661 gggctacttc gtttacgata cgtacagaga ttttttgcaa gacttcccat gggatacggg
    15721 caaagtcagc ggtcattccg tcgattgaag ttacagcacg gataccgact gtgtagtcgt
    15781 aagtacgtcc gtcacccata acaccgacag agcggatccc tggaagaaca gtgaaatatt
    15841 gccagatatc acggtcaagt ccagcagctg cgatttcttc acgcaagata gcatcagatt
    15901 cgcgtacgat ttctagcttg tcttcagtga tttcgccaag aacacgaata ccaagaccag
    15961 gaccagggaa tggctgacgc caaacgattg aatcaggcat gcctaactga gtccctaatt
    16021 cacggacttc gtctttgaat aatgtgttta atggttcgat caattcaaat tgcatatctt
    16081 ctggcagtcc acctacatta tggtgagatt tgatcgtctg tgctgtttct gtaccagatt
    16141 cgataacgtc agtatacaac gttccttgtg ctaggaaaga gacgccttct tcaccagcaa
    16201 gttttgttgc ttcgtcatca aaaacatata cgaattcatt cccaatgatt ttacgttttt
    16261 gttctgggtc agatacacct ttcaacttgt ctaagaagcg atctcttgca ttgactttga
    16321 tgatgttcaa gccgaatttt ccgcctagac tttccattac ttgttccgct tcgcctttgc
    16381 gtagcagacc gtggtcaaca aagatagatg tcaattggtc accgatcgct ttttgtaaaa
    16441 gaaccccaac gacactagaa tcaacgccac ctgaaagacc aagcaagact tttttgtcac
    16501 caacttgttc acggattttt tctacttgca tatcgataaa gttatccatt gtccagttac
    16561 cttcacagtg acaaacatca aaggcaaagt ggcgcagcaa ttcgattccg tattcggaat
    16621 gacgtacttc tgcatggaat tggataccat aaaaattacg tgttgtgtct tggatagaag
    16681 caatcggaca atctttgctt gttccgactg tttcaaagcc ttcaggaact ttagttacca
    16741 agtcaccatg gctcatccat actgtttgtt gttttggtgt ttctttaaac aagacagctt
    16801 gatcgcttgt tacttctaac aaggctttcc catattcgcg gtttttagca ggctctacgg
    16861 aaccgccaag tttgtacgtg atcaattgca taccatagca aatccctaat acaggaatac
    16921 ctaaattgaa gatctcagga tcgatcccaa atgcattctc atcatataca ctgtttggtc
    16981 cgccagaaag aatgattccc tttggattca tcgcttttac ttcttctgca gtaatgcggt
    17041 ggctcaataa ttcggaaaag actccaagat cacgaatacg tcttgtgatc aattggttat
    17101 actgactacc gtagtctaat acgataatct tttcaacgtt cgtcatatcg gcaacgtttg
    17161 tcaaatttat tacccctatc cctttaaatt ttatctcaaa atagtcaaac tattttaaaa
    17221 tgctaatatt ttcgcatgaa aatcgaatcg atgatatgat tttcagtttt atggagaatt
    17281 atatcggctc ttcctcgtgt aggcaagata tattcctgta aatttttcaa attcacattt
    17341 ttccatacat cttttgccat tttaaaggct tcttcacgat ctccgatagc aaaacgataa
    17401 taataattct ctggattttg gaaagccgta tccagtaacg caccaaaacg atccaaatac
    17461 catttttcga tcagcacggg atcggcatcg acatagacag aaaaatcaaa aaagtcgctg
    17521 acgtagattt gctgattcgc aggtaattga agcgtattga tcccctcaac gatcaagata
    17581 tcaggctgct ggatcaattc gtacttgtct ggaatgatat catacacatc atgtgagtaa
    17641 acaggtactt ttatctcttc ctgaccagat tttacacggt tcaagaaatc gatcagcatc
    17701 tccatatcat aactttcagg aaatccttta cggtccatga ttccacgctc ttttaatata
    17761 cgatttggat aaagaaatcc gtcagtcgtg atcagctgaa cgtttcttcg tttgaaggta
    17821 cgagacaaaa tcgtctgcag cagtctggct gttgtacttt ttccaacggc tacacttccg
    17881 gcgatcccga taataaaagg cggtacttct acgtatttat gaagaaataa acctttactc
    17941 aagaacaaag attcaaattc tttcatataa agataaatca gatgagcaag aggtacatag
    18001 atatctcgaa catcctgcat ggaaatgcgg tcattcaaac ttttgatatt atctagttca
    18061 tcttgtgtca aaggtgcttg cccattacga taaaattctc gccattcttc tcttgccaca
    18121 cggtagtagt tcattggatc attcatatta gcctcctgcg ttctcccatc aatggaacta
    18181 ttttaacaca aaataaacgc aaaccccacc acttaagaga gattgccgat ctttttgtat
    18241 aatctttata atagaaagaa acggagtctt attcttgact tgcgcacgga tacataaaag
    18301 gatagactgt tgtcatgaaa gaaatgagaa ggatggaaga catgacaaat cattactatt
    18361 ctgaacgccc agatacggcg cacgattttg aacaatgggc ttttgagtta aaaggcagaa
    18421 cctttcaatt tgtaacagat tctggtgtat tttcacgtga aacagtggat tatggttcac
    18481 gtgtcctgat tgatgctttc gattgggaag agttacctga tgaaggaaag atcttagatg
    18541 tgggatgcgg gtatggaccg attgggttag ctttggcatt tgcgacacag cggtttgttg
    18601 aaatggtcga cattaatgaa cgagcggtaa gtctagcgca aggaaacgca aagcgtaacc
    18661 aaatcgaaca tgttgatatc catcaatcga atatctatga agcagttcat gaagaaacct
    18721 atgcagctat cgtaagcaat ccgccgatcc gtgctggaaa aaaagttgta catgaaattt
    18781 tgacaggcgc atatcctcgg ttgaagaagg gcggtacact gacaattgtg atccagaaga
    18841 aacaaggagc gccgagtgcg caaaagaaaa tggaagaaac atttggtaat gcagaaatcg
    18901 tcacaaaaga taaaggatat tatatcatca aaagtgtgaa agaataacta gctgaaaaat
    18961 agtggagcga cgaaagagtg gaactgggcg tgcatgtacg ggtacgtatc agttcttttt
    19021 ttgttgagaa gtttttaaaa acaaagaact attttttctt caaaaagaaa tagtaggaac
    19081 agagtcgttg ttttttacga taaaataaat aagatacaga acttgtatag aaggctgcca
    19141 agtcggtaga taaaggaggt ttttatcaaa aaacatactt tccttttttc tctattcttt
    19201 tcttgggggt tttggtacac tgatagggaa tttagataga agggagccaa taggatgaag
    19261 ctgaccatca gagatatcgc agaaatggca ggcgtatcag taacaactgt ctcacagatt
    19321 ttgaataaca aaggaagcag atttagtgat aagacaagaa aaaaagtgtt gtcgatcgtg
    19381 aatgaacatc attataagcc cgattatttc gcttcaaatg tgatcaatcg acattcaaag
    19441 accatcggaa tgatcgtccc tgatgtcact gatttcttct tctccaaact gatcgaaggt
    19501 gtagagagct atttgaatcc tttgggctat gtgatcatgt tatgcaattc tcgtcatagc
    19561 caagaaaatg agatcaagta tttacaagag ctttcccacc gctcagtgga cggaatcttg
    19621 ctggccacac caaatatttt acctgagaaa tatgcattag acagcggttt ttatcaaaaa
    19681 atgccaatca ttttaatcga tcgcggattg aatcgtcggg ataacggacg gcttatcgta
    19741 aaggaatatg agggcgccta tcaagctgtt tcgctgttta ttgaaaatgg ccatacgaag
    19801 atcggcatgc tgaaggaaac cactggatac tatcaattag aagaacgttt caacggatat
    19861 cgtcatgcgc tgaaagatca tggcctgcct tttaatggga aatttgttga acatggagag
    19921 ttgactgtcc aaggtggata tactgcatca aaaaaattac tcaaacataa agatatcacg
    19981 gctatttttt gcgggaatga tgccatggcg atcggatgct atcaggcgat cgatgaattg
    20041 ggcaaaaaaa tcccagaaga tatctcagtc ataggattcg atggattaaa gctgtcagaa
    20101 tacatgattc cgcaattgac gacagtgcag cagccaagtt ttgatattgg attttatgct
    20161 gcacgtttcc tgatcgatac gatcgaattt cctcaaagaa aagttccgaa caaagtgttc
    20221 gaaacaaaat taattattcg tgagagcgta aaagtattga caaagggcta actcggcggt
    20281 atattgctta tgtaagcatt tacaaaggct agttagtgct ttttttattt ttagtaaacc
    20341 agtttactaa agtggtttac ctttcctaaa aataatgtat aataccgaat gaagacaagg
    20401 aggatcaggc aatgcgaatg gtggatctga ttgaaaaaaa gagggatgga aacgagctgt
    20461 cgaaagagga aatcgagtac atcgtcacga actatacgaa tggaaagatt ccagattatc
    20521 aagtcagtgc attattgatg gcaatttttt atcaagacat gacaaatgaa gaaatcacga
    20581 acttaacatt ggcgattgct aattctggtg atgtcatcga tttgagttct cttgaaggaa
    20641 taaaggtaga taagcattcg acaggtggcg ttggtgacac gaccacattg attttagccc
    20701 ccctagtagc tagtgtcgga gtgacagtgg ctaaaatgtc tggacgcggt ctaggttaca
    20761 caggtggtac actagacaag ctagaagcaa ttcccggatt tcagatcgag ctttcggatg
    20821 aagaatttgt acgcattgtt aatgaaagta aagtagcggt aattggtcaa tcaggaaact
    20881 tggcaccggc ggacaaaaaa ttgtatgcct tgcgtgacgt cacagcgacc gttgattctc
    20941 ttccgctgat tgccagttcg attatgagta aaaaaatcgc ggcaggagca gatgcaatcg
    21001 ttttggatgt gaccactgga gacggtgctt tcatgaagaa catcgaagat gcaagacgtc
    21061 tggcaaagac catgacgagc attgggaaac tggctaaccg agaaacagtg gcggttatct
    21121 cagatatgtc agaacctctt ggcgaagcta tcggaaatag tctagaagtt gtcgaggcaa
    21181 tcgaaacatt acaaggaaat ggtccagaag atctagtaga aatgtgctac gccttaggaa
    21241 gccaaatggt tgttcttgct ggcaaagcta agacaaccga tgaagcaaga acgttgcttc
    21301 aagaagctct ggaatcaggt aaagcgttag caaaattcaa agaaatgatc caaaatcaag
    21361 ggggagaccc agcgatcgtg gaacatccag aacgaatttt gactgcacgc tacacaatgg
    21421 agcttcctgc taaacaaagc ggagttgtgt caaaaatcgt ggcaaatgaa ttaggaattg
    21481 ctgcaatgat gctaggtgct gggcgtaaaa ccaaagaaga agatattgat cacgctgttg
    21541 gattgaaact gcataaaaaa attggtgaca ctgtgacaaa aggtgagtca ctattgacga
    21601 tctatagtaa cgacgaagaa atcacttctg tcattgaatt attatataaa aatattgaaa
    21661 ttggtgaatc ggcaatgaag ccaacgttga ttcatgacat catcacagaa taaaggaaaa
    21721 aagcggactt taccgtttta aagaaaaggg gaaaagaaat ggaactaaac cgaatgatcg
    21781 accatactat tttgaaagca gacgcatcta aagaagctgt gatgcaaatt atcgaagaag
    21841 caaaaaaata ccatttttat tctgtctgca tcaatccagc atgggttgcg ctagcgaaag
    21901 aacaattaca aggtgagcca gtagccgtat gtacagtaat cgggtttcct ctaggagcaa
    21961 acacacccga gacaaaagca tttgaaacaa cagatgccat caataacggt gcagatgaag
    22021 tcgatatggt catcaatatc ggtgctttga aatcaaagga tgatcaacaa gtccaaaaag
    22081 atatcgaagc agttgttgaa gcagcaaaag atcgtgcgct tgtcaaagtt attattgaaa
    22141 catcgttatt agatagagaa gaaatcatcc gagcttgcga aatagcaaaa gctgcaggcg
    22201 ctgattttgt caaaacatca actggtttct caacaggcgg agcaaaggta gaggatgtcc
    22261 gtttgatgcg tgaaactgta ggaccagaaa tgggtgtcaa agcttccggc ggtatccata
    22321 acgaagaaga agcaatggca atgatcgaag ctggtgctac aagaatcgga acaagcgcag
    22381 gagtagcaat cgtatctggt tcaactggtg aaggctatta attttttcaa aggagaagct
    22441 catggcagaa ctcaaacaag aatggatcaa cacagctatt gaagcgttag ataaagccta
    22501 tgttccttat tcccattttc cggtaggcgc ttgtctcgta acggaatcag gcaagattta
    22561 tcaaggcatc aacattgaga atgcatcatt tggattaacg aattgtgccg agcgcacagc
    22621 ttttttcaaa gcagtatctg aaggagaaaa aacatttacg catctagtcg tagcggggca
    22681 cacccccgat cctatctctc cttgtggtgc atgtcgacaa gtaatggcag aattctgttc
    22741 ccctgatatg ccggttacgc tagtaggaga caatggtgtg acgaaggcaa cgaccgttcg
    22801 tgcactgctg ccttatgcat ttactgaaaa agatctataa ctcatgttca ttcagtcagc
    22861 tgactgttga aaaataaaac aattatttta ggaggcttta cagaaatgaa aaaagcaaaa
    22921 ttatttggtt taggtgctgt cgcactagca gcagggttat ttttaggtgc atgcggcaac
    22981 aacggctcta ctgattcatc cggtggcaaa agctcatcag acacaacaac tgcagcattg
    23041 atcacagaca caggtggtgt agacgaccgt tcattcaacc agtcagcttg ggaaggacta
    23101 gaaaaatggg ggaaagatca aggactttca cgaggaaatg atggcttcca atatttccaa
    23161 tcttcaaatg aatcagatta catcccaaat attgaccaag cattgaatgc tggattcaaa
    23221 acgatttttg gtattggtta taaactaaaa ccagcgatcc aagaacaagc aacaaacaat
    23281 acaggtacga actttgttat tatcgatgat gtcatcgatg gattagataa cgttgtatct
    23341 gcaactttca aagacaacga agcttcttat cttgcaggtg ttgcagcagc ttatacgact
    23401 gaaacaaacg tagtcggctt tatcggcggt gtaaaaggtg aagtaatcga tcgttttgat
    23461 gctggattca aagccggtgt tgatgcaggt gcgaaagaat taggaaaaga aatcaaagta
    23521 ttgaatcaat atgctggtga cttctctgct ccagataaag gacgttcaat tgctcaaggt
    23581 atgtatgcac aaaacgcaga tatcatcttc catgcttcag gcggtacagg taacggtgta
    23641 ttccaagaag caaaatcatt gaacgaatca ggcgacaaaa aagtttgggt tatcggtgtt
    23701 gaccgcgacc aatcagacga aggcgaatac acattaaacg gcgaaaagaa aaacttcaca
    23761 ttgacatcta cactgaaagc agttggaaca gtagtagaag atttggcaca aaaatcagcg
    23821 gacggtaaat tccctggcgg cgaacacact gtttatggat tgaaagaaga cggtgttggt
    23881 ctaacagaag gacaactttc tgacgaagcg aaaaaagcag ttgatgaagc aaaagaaaaa
    23941 atcatttcag gtgacgtaaa agttccagaa actcctgaag aaaactaaaa ccatttctat
    24001 agccttgtta gacacatgtt tgacaaggct atggtttgat tagaacaaga attgttcatt
    24061 tatccaagct gccttgtgac agtttggata agggaacaac tccctgaagt aatgtttgtt
    24121 tcaaaagaag aacgctcact aagcgtgaat cttagtcaat cgttgcccta gatagaaatc
    24181 gttaggatgt gaaaaaaagg tggttcaaga aaatattgtc atagaaatgc agaatattac
    24241 caaagaattt ggaacattca aggcaaatga caacatcaat ttacaagtaa aggcaggaga
    24301 aattcatgcg ttgcttggag aaaacggtgc tggcaaatct acattgatga acgtgctttc
    24361 cggattatta gagccgacat cagggaaaat tttgatgcgt gggaaagaag taaagatcac
    24421 aagtccgacc aaagccaacc aattagggat tgggatggtc catcagcact ttatgcttgt
    24481 tgatgccttt actgtaacag aaaacatcgt gttgggaagc gagcctagtc gcgcagggat
    24541 gcttgaccat aaaaaagcac gaaaagagat ccaaaaagtt tctgaacagt atggattgtc
    24601 agtcaaccca gatgcttacg ttcgtgatat ttcagttgga atggaacaac gggtagaaat
    24661 tttaaaaaca ctttaccgag gagcagatgt actgattttt gatgagccga cagctgtatt
    24721 gacccctcaa gaaattgatg aattaatcgt gatcatgaag gaattagtca aagaaggcaa
    24781 gtcgatcatt ttgattacgc ataagttaga tgaaatcaaa gcagtagctg accgctgtac
    24841 agttatccgc cgtggaaaag gaatcggtac agtcaacgtt aaagacgtaa cctcacaaca
    24901 attagccgat atgatggttg gaagaacggt ttcattcaaa acgatgaaaa aagaagcgaa
    24961 gcctcaagaa gtcgttttgt ctattgaaaa tctagtggtg aaagaaaatc gtggattaga
    25021 agccgtgaaa aacttgaact tagaggttcg tgctggcgaa gtacttggta tcgctggaat
    25081 cgatggaaac gggcagtcgg agttgatcca agctttgact ggtttgcgaa aggcagaaag
    25141 cggacatatc aagctaaaag gggaagacat cactaataaa aaaccccgaa aaatcactga
    25201 acatggtgta ggacacgtgc cagaagaccg tcataaatac gggttagtcc tagatatgac
    25261 attatctgaa aatatcgcac tacaaaccta tcatcaaaaa ccttacagta aaaacggcat
    25321 gctgaattat tcagtaatga atgaacatgc cagagaattg atcgaagaat atgatgttcg
    25381 aacaacgaat gaacttgttc ccgcaaaagc tttatcaggc ggaaatcagc aaaaagcaat
    25441 tatcgctcgt gaagtcgacc gagatcctga tctgttgatt gttgcaaatc caactcgtgg
    25501 actggatgta ggtgcgatcg aatttattca taaacgtctg atcgaacaaa gggacaaata
    25561 caaagcagtg ttactgatca gtttcgaatt agaagaaatt ttaaatgttt cggatcgtat
    25621 tgctgttatc catgaaggag aaattgtcgg tatcgttgat ccgaaagaaa catctgaaaa
    25681 tgaattaggt ctattgatgg cgggctatac cttagaagaa gcacgaaaag agttagaaaa
    25741 gggggctggc gcacatgaat gatcgcagcg aaaaattccg taatttatta gtgcctgtac
    25801 tttcagttgt tttaggattg atcttaggcg cgatattgat ggctgctttt ggttttcagc
    25861 ccatccaagg ttattcttct atgctagatg cagcccttgg ttcgcaaaga gggataggtg
    25921 aaacgttaag gcaagcaacg ccgttgattt ttacagcatt aggtttttct gtagctaact
    25981 cagctgggtt tttcaatatt gggctttctg gacaagcact ttgcgggtgg atcgtcagtg
    26041 tctgggtggc acttgcgttt ccagatctgc caaaagttgt tttgcttccg ttatgcgtga
    26101 tcttaggtgc cttagctggt gcgatggcag cggctgttcc aggtttactt cgagcatttt
    26161 ttggaacaag tgaagtgatc gtaacaatca tgatgaacta tatcttatta tacgtaagca
    26221 catttgcttt acatgaagtg atgcctgaaa gctatcgctc aagtttggac tcttccaata
    26281 tgatcagtca aaatgcctca ctgcggttac catggttaac acaagctttt ggcggctctc
    26341 gcgtaaactc aggattattt ttagcaatca tcgcgcttat tttcgtttgg ctgctgatga
    26401 agaaaacgac tttaggattt gaaatccgtt ctgttggatt gaatcctttt gcttctgagt
    26461 atgcaggaat gagtagtaaa cgtacgatcg ttttgtcgat ggtcatttct ggcgctttgg
    26521 cagggcttgg cggtgtggtt gaaggattag gaacgtatca aaacttcttt gttcaaacga
    26581 cttcgctatc tattggattt gacggaatgg ctgtttcctt gcttggttct ggatcagcaa
    26641 tcggtattct tttatcagcg atcttgttca gtattttgaa gatcggtgga cttggcatgc
    26701 agacaggagc aggtgttccg tttgagatcg tcaatgtatc gattgctttg attatcttct
    26761 ttgtcgggat caacttcctg attcgtttcg tcatggctaa agtcttccaa gggaaaaaac
    26821 aagaagagat cgttgcgaca atagaatcga aaccaacgaa tcaaaaccat gaagggggcg
    26881 aactataatg tcgactatcg aattaattgc cttgatcctt acttctacac tggtttattc
    26941 aacaccgcta attctaacgt cactaggcgg aactttttct gaacgaagcg ggatcgtaaa
    27001 cgtagggcta gagggaatca tggtcatggg tgcttttagt tccatcgttt tcaacttgac
    27061 gatgagtcca tcacttggtt ctatgacacc atggatcgct attttagtgg gtggcgtcgt
    27121 aggtatccta ttttctctga ttcacgcagt agcaacagtc agtttgcgtg ctgaccatat
    27181 tatcagcggg acagtaatta atctgatggc acctgcttta ggtgttttct tgatcaaagc
    27241 atggtatggt aaaggtcaaa ctgataacat cacgcagaat ctggggtatt tttctttccc
    27301 aggattagca gatattccgg tcattggacc aattttcttt aaaaatacat tcttacctgc
    27361 ttattgtgct attttgattg ctgtcctagc ttgggtgatc atcttcaaga cgaaattcgg
    27421 cttgcgcctc cgttcagttg gtgaaaatcc tcaagctgcc gacacattag gtatcaatgt
    27481 atatgctatg cgttattcag gcgtactgat ttctggcttg ttaggcggta tgggcggtgc
    27541 tgtttttgct cagtcgattt ccggtaactt ttcagctggt acgatcgttg gacaagggtt
    27601 catctccatg gctgctatga tctttggtaa gtggaatcct ttaggggcaa tgggtgcctc
    27661 attgttcttt ggttttgctc aaagcttgag tatcattggc gcacaattac cagttatttc
    27721 ttcgattccg ccagtattgc tgcaaattgc tccatatttg ctgacaatca ttgtgctggt
    27781 tgttttctta gggaaagctt ctggtccaaa agcaaacggg aagaactata tcaaatcaaa
    27841 ataatctttt agcgaataaa aagggtgggt tacgggaagt gtttttcgtc tcgccctttt
    27901 tgttttaaag gcaataaaaa taaaaagaaa gaaggaataa tcatgtttaa acgcgtacat
    27961 ctgatcgtca tggattcagt aggaattgga gaagcaccag atgccgataa gttcggtgat
    28021 gttggttctg atacattagg acacattgcg aaagaagcag gattgaacgt tccacattta
    28081 gagcagcttg gtttaggaac gatccgtcct cttgaaggtg tggaatcagt gaaagatcat
    28141 caaggctatg cgacgaaatt agaagaagtt tctgtaggga aagatacgat gacaggccac
    28201 tgggaaatca tgggattgaa tatcaaaact ccatttcgtg tgtttcctaa tggattccct
    28261 gatgatctga tcaaacaaat cgaagaattt tctggccgta aagtcgtatg taacaaacct
    28321 tatagcggaa cagctgttat tgacgattac ggtgaacacc aaatgaaaac aggcgattta
    28381 attgtatata cttctgccga tcctgtcctt cagatcgcgg cacatgaaga aatcattcct
    28441 ttagaagaat tatatcggat ttgccaattc gttcgtgata taacaaaaga tgatccgtat
    28501 atgattggcc gaatcattgc acgtccgtac gtgggtgaac caggagactt cacacgaaca
    28561 agcaatcgcc atgattatgc gttgaatcca ttcggacaca cagtccttga ttctttgaaa
    28621 gaagcaggaa aggacgtgat tgctgttgga aagatcaacg atattttcaa cggacaagga
    28681 atcactgaat ctgtccgcac gaaaagcaat atggatggcg ttgaccagct gctgaaagtt
    28741 atgaaaaacg atttttcagg aatcagcttt accaatttag tagattttga tgcattatac
    28801 ggtcatcgtc gggatgtagt cggctatgcg catgcgattg aagaatttga cttacgaatt
    28861 ccagaattgc ttgaagcgat ggaagaagac gacttgctaa tgattacagc cgatcacgga
    28921 aacgatccga cgtttactgg taccgatcat acgcgagaat atgtaccgtt attggtttac
    28981 agtaaaaaaa tgaaagaaca aggggcattg cctcaaggat attattcaga tatttcagca
    29041 acgattgctg agaactttag tgtttcttcg actgaaaatg gcgaaagctt cttgaaatta
    29101 ttaaaataat ctttttaaat aggagaaagc aaatgaccaa gttaagcgag atgttacaag
    29161 aaacgaccca gtttatcctt gataaaggag taaaagaaat tgattttggt ttgattctag
    29221 gttcaggatt aggtgaatta gcagatgaaa tcgaagatgc tgtaatgatt tcttatgatg
    29281 agatcccgtt ctttcctgtt tcgacagtag ttgggcatgc aggaaagcta gtttatgggt
    29341 ctctggcagg caagaaagtg ttagccatgc aagggagatt ccactactat gaaggtcatt
    29401 ccatgcaaac agtgacctat ccagtacgtg tgatggccgg actaggggcc cattcagtca
    29461 ttgtgactaa tgcatgtggt ggtgtcaacg aatcatttgt accaggagat ttgatgctga
    29521 ttaccgatca tatcaatttt actggtgaaa atcctttgat cggtccgaat gaagatgcaa
    29581 tgggccctag atttccagat atgagtcaag cttatacgcc tgactatcaa gcaacagcaa
    29641 aagcagcagc agaaaaacta ggtttggatc ttaaagaagg cgtatatatg ggctattctg
    29701 gaccaactta tgaaacgcct gcggagatcc gaatgtctcg gacaatagga gccgatgcag
    29761 tagggatgtc gactgttcca gaagtcatcg tagcagctca cagcggatta aaagtgttag
    29821 gaatctcttg tattaccaac ttagcagcag gtatgcaagc gaatctgagc catgaagaag
    29881 ttgtagaaac aactcagaga gtcaaacaat cttttaaagc attggttaaa gaaacattga
    29941 cattattgta ataggaggaa caataaaatg agtgtgcata ttgaagcgaa agaaggcgag
    30001 atcgccgata agattttact tccgggagat cctttgcgag ctaaatatat tgcggagact
    30061 tttttggaag atccagtttg ttacaatcag gtacgcggta tgttaggctt taccggcaaa
    30121 tataaaggag aacgtatttc tgttcaagga acaggaatgg gaatgccatc agccaccatc
    30181 tatgcccatg aattgatcca gtcgtatggt gtaaagaaat tgattcgagt aggtacatgc
    30241 ggtgcattgt caaaagacgt ccatgttcgt gatttagtac tagcacaagg tgcagcgacc
    30301 agttcttcga tgatcgaaaa aaatttccaa gcctttcatt ttcctccaat cagtgatttc
    30361 aatctattac tgaaagcata tgagatagct aaagaaaagg gctatacggt tcatgtagga
    30421 aatgttcttt cggaagattc tttctacaaa gatgatttga cagagacgtt ccaattagct
    30481 gaacttggcg ttttaggagt ggaaatggaa gcagcggctc tttattactt aggcgcgaaa
    30541 taccatgtgc agacattaag tttgatgacc gttagcgacc atttgatcac cggtgaagaa
    30601 acaacagctg cagaacgtca atctacgttc aatgaaatga tcgaagtagg attggaaaca
    30661 gcgatagcag aataagaagg aaatgaaaaa gctgccctgc attaagtaat aagaacatcc
    30721 aagcaaaaat agctcctcat gtttttgact tggctggact tattattgca aatgtaagct
    30781 tttgaacacc gtttaccaag aggttgtgaa tctgccgttt aactctgagt cacaaggaac
    30841 aatttcaaaa aacagctttt catgtttgat gaatattgtg acttgtgacc gagaagttgg
    30901 caggagaaaa ccgtttatac gaaaaaaggg actgtgacaa atcgtgtcac agtccctttt
    30961 ttatagtgtt ttttataggt agtatttttt agcaactgtt aagtcatcat ttaattcata
    31021 aacaagtggt tgacctgttg gaatttcaag atccatgatg tcttcgtcag agataccttc
    31081 gatatgttta gctagggcgc gtaatgagtt accatgtgca gctactaaaa cagttttgtt
    31141 gtctagtaat gctggagcaa tttcatcttg ccagaatggc aaagcgcgtt ctaatgtcac
    31201 tttcaagttt tctccaccag gaatatcgcg tttgtctaac attgcgtaac gacggtcatt
    31261 tgctgcagaa ccttcgtcag tttcttccat taatggagga agagtatcgt aagaacgacg
    31321 ccagatgtgc acttgttcgt cgccgtattt ttcagctgtt tcttttttgt tcaaaccttg
    31381 taatttacca tagtgacgtt cgtttaagcg ccatgatttg atttgtggta cccaaagttg
    31441 atctgaatat tctaagatca agttacatgt tttgattgca cgagttaaaa cagaagtgta
    31501 agcaacatca aattcgattc cagcttcttt gattttgcgt ccgccttctt ttgcttcttc
    31561 gattccttct ggtgctagat ttacatcagc ccaaccagta aattggttca atgcattcca
    31621 ttcactaaga ccgtgacgag aaaaaactaa ttttggcatg tttagctctc cttttaagat
    31681 aggtttatat ttctgaaatt ttcagttctg ttttattgta caattttttg gaagagattt
    31741 ccatcgaaaa attagataag attctatgag aaaacaagta gagaatataa aaaaacgaac
    31801 agtgcccacg caactgttcg tttttaggta ttagatgcat aattgctcga tttctttttc
    31861 aggtaaattg atatatttat aacatgttcc aactgaaaca ccgcattttg aagaaataaa
    31921 ttggatcgtt tctttttttt cataatagag acgtcggatt tttttgatcg tttttgcatc
    31981 gatttttggt cttccgccga tttttccttt tttacgagct tcatctaatc caactaatgt
    32041 acgttctttg atcaatgcgc actccatgtt tgctaggttt tccattaatt ggaaatagat
    32101 ttttcccatt tcgcgcgtat cgattccttc atcaagacta atcaagtgca gcccgcgatc
    32161 tttgaataat tgcgtgagtt ctgttaattg ccgcgtagat ttgcctaatc gatgaagttg
    32221 gcaaatgact agtgcatcgc cttgttgcat gtcagcgatc actgactcca aatgaacagc
    32281 agtagaatca ttttgttcca cttcatatgt ctcatggaaa atttcttgac aaccaaagtc
    32341 agataattga tcaacctgag ttgttaaatc aacgtcattt atggttgtgc gtgcataacc
    32401 aataattttc atggtgattc ctttctagca gtgattttct aactggatat aacagtaaaa
    32461 atgtagcata aagtacgtca aaaagatagt tttttcgcaa attttccgct gtcttttttt
    32521 attggatgat caagcagttt ttctttattt acgacggatt gcgtcaagaa tctcaacgcc
    32581 tttttctgag ccgacaacta ctttagaaac catgtttagg aaaagcccat gttctactac
    32641 cccaacaagt tcatctaaat aggtagctaa gctttctggc tgttcgatga cttctagatg
    32701 cagatcaatg atgtaatgac caccatctgt ggttaagact tctccgtttt cgtctgtacg
    32761 caagacgggt tggaatcttt tttcttcaaa aatatgaagt agctgttggg agccataagg
    32821 gatcacttca actgggagtg ggaacttccc aagtttatcg actaatttag aagaatcaac
    32881 gatccaaatc gtttcttttg agtacgtagc gactattttc tcgaaaagca aagcagcgcc
    32941 gccgcctttg atcccttgaa aatcagcact gatttcatca gcaccgtcta ttgtcaaatc
    33001 gactacgggg acttcatcaa tactctttaa cggtattcct aatttttccg cttgttcttt
    33061 tgtcgcattt gaagtagtaa ctcctgtgat acgtaaacct tcttcacgca tacggcgacc
    33121 aatctcttct accatataat aggcggttga accggtcccg agacctacga tcatcccgtc
    33181 ctttacgaat ttcgcggctt caatgccagc taattgtttt aaattcatct ttgcgtccac
    33241 ctttttttag tttgagcatc gtgctttcct cactatttta gcgtgattta cggtaaaaag
    33301 ataccattct tttttattcc aataaagctt tttcaaaaaa aattgcatct cttgttgaca
    33361 tgttttttca ttcgtgatat tctaacaaag gtgctttatc tacaggtttc tgtgaagaaa
    33421 cgtgctgact gtttatcaaa gcatatttga taaggatgca gacattgcat ttatttttta
    33481 tcacaaaaaa agaaccacct ggatgtgtgg aactagacgc aaatcgtggg aaggaggaaa
    33541 caaggaatgc ctacaattaa ccaattagta cgtaaacctc gtaaatcaaa ggtggaaaaa
    33601 tctaattcac ctgctttgaa caaaggatat aacagcttta agaaaactca aactaacgta
    33661 aactcacctc aaaaacgtgg ggtagcaact cgtgtgggta caatgacacc taaaaaaccg
    33721 aactcagctt tacgtaaata tgcacgtgtt cgtttgtcaa acttaattga agttactgct
    33781 tatatcccag ggattggtca taacttacaa gaacacagtg ttgtattatt acgcggtggt
    33841 cgtgtaaaag acttaccagg ggtacgttac catatcgttc gcggtgcttt agatactgct
    33901 ggtgttaacg accgtaaaca aagccgttct aaatacggaa ctaaaaaacc taaagcttaa
    33961 ttttaattat taaacaaatg aaacttgctt ctactatata gaagtaatta ctatgaacaa
    34021 tatttcggaa ggaggagtta cggatgccac gtaaaggtcc tgttgcaaaa cgtgatgttt
    34081 taccagatcc tatttataac tcaaaattag taactcgctt gatcaaccgt gtaatggttg
    34141 acggaaaacg cgggattgca gctaacatta tctataatgc ctttgacttg atcaaagaat
    34201 ctacaggtaa cgatccatta gaagtgtttg aacaagcaat gaaaaacgtt caacctgttc
    34261 ttgaagttaa agcacgtcgt gttgggggtt caaactacca agtaccagtt gaagttcgcc
    34321 ctgaacgccg cgttactcta ggtcttcgtt gggtagtaaa ctacgctcgc ttgcgcggtg
    34381 aacacacaat ggaagaacgc ttagcaaaag aaatcatgga tgctgcaaac aacacaggtg
    34441 cttctgttaa aaaacgtgaa gacactcata aaatggctga tgccaaccgt gcgtttgctc
    34501 actatcgctg gtaagattct ctctgtttgg tcggctttta taagtcgacc tcagatagtg
    34561 tccttatttt tagcaactag atagtaaaga gaggagaaac aaggagaatg accagagaat
    34621 tttctttaca aaacactcgt aatatcggta tcatggccca catcgatgct ggtaaaacga
    34681 ctgctactga acgtatcttg tactatactg gtaaaatcca taaaattggt gaaactcatg
    34741 aaggagcttc acaaatggac tggatggaac aagaacaaga acgtggtatt acgatcactt
    34801 ctgctgctac tacagcacaa tggaagggtc accgaatcaa catcatcgac acaccaggac
    34861 acgtagactt cacagttgaa gttgaacgtt cattgcgtgt acttgatggt gctgtaactg
    34921 ttcttgatgc acaatcaggt gttgaacctc aaactgaaac agtttggcgt caagcaacaa
    34981 cttatggtgt acctcgtatc gtatttgcaa acaaaatgga caagatcggt gctgacttct
    35041 tatattcagt atcaacttta catgaccgtt tgcaagcaaa cgctcaccca atccaattac
    35101 caattggtgc ggaagacgac ttcacaggaa ttatcgacct tgtaacaatg aaggctgaaa
    35161 tgtatacaaa cgatcttgga acagagatcg aagaaacaga aattcctgaa gaataccgcg
    35221 aattagctga agaatggcgc gaaaaattgg ttgaagctgt agctgaaact gatgaagaac
    35281 ttactttgaa atacttagaa ggtgaagaaa tcactgaagc tgagttaaaa gaaggtatcc
    35341 gccgcgcaac agttaacgta gaattctacc cagtactatg tggttcagca tttaagaaca
    35401 aaggggttca attactattg gacgctgttc ttgattactt gccatcaccg ttagatatcc
    35461 cagctatcaa agggattgac cctaaaactg atgaagaagt agaacgtcct gcagacgaca
    35521 gcgctccttt ctcagcttta gcatttaaag ttatgactga cccattcgta ggtcgtttaa
    35581 ctttcttccg tgtgtactct ggtgttttac aatcaggttc atacgtacaa aacgcaacaa
    35641 aaggcaaacg tgaacgtgtt ggtcgtatcc tacagatgca tgccaactct cgttcagaaa
    35701 tctctgaagt ttacgctgga gatatcgctg ctgctgttgg tttgaaagac acaactactg
    35761 gggacacact atgtgatgaa aagagtctag ttattcttga atccatggaa ttcccagaac
    35821 cagttatcca agtcgctatt gaacctaaat caaaagctga ccaagataaa atgggtgtgg
    35881 ctttacaaaa actatctgaa gaagatccta ctttccgtgc tgaaacaaac gtggaaacag
    35941 gcgaaacaat catcgctggt atgggtgaac ttcacttaga tatcatcgtt gaccgtatgc
    36001 gtcgtgaatt caaagttgaa gctaacgtag gtgcgcctca agtatcttac cgtgaaactt
    36061 tccgtgctgg cactcaagcc gaaggtaagt ttgtacgtca gtctggtggt aaaggtcaat
    36121 acggtcacgt atggattgaa tttacaccaa atgaagaagg tgctggtttc gaatttgaaa
    36181 atgcgatcgt cggtggggtt gttcctcgtg aatacattcc agctgttgaa actggtttga
    36241 aagatgctat ggaaaatggt gtcttagctg gctatccatt agtagatatc aaagctaaac
    36301 tttacgatgg ttcataccat gatgtcgatt caaatgaaac tgccttccgt gttgctgctt
    36361 ctatggcatt acgtgcagca gctaagaaag ctaatccagt aatccttgaa ccaatcatgg
    36421 ctgtagaagt tgttatccct gaagattatt taggtgatgt tatgggtcac gtaactgctc
    36481 gtcgtggacg tgttgaaggt atggaagctc gcgctggcgg ccaacaagtt gttcgtgcga
    36541 tggttccact tgctgaaatg tttggttatg ctacaactct tcgttctgct actcaaggtc
    36601 gtggtacatt tacaatgaca tttgaccact acgaagatgt accaaaatca gtacaagaag
    36661 aaatcattaa gaaaaacggc ggaaaagctg aataatttct tgaaaccgga tagtcctgca
    36721 aagagattat ccaaagagac tatattttta atatagtttc gtgtaaaata attatcgatg
    36781 atatgggcat gtggtgtacc ttgtgtacat catataccta tcagacaaat aaaaaatata
    36841 ttgtattttt aggaggacat tttaaaatgg caaaagaaaa atttgaccgt tctaaaccac
    36901 acgttaacat tggtactatc ggacacgttg accatggtaa aactacatta acagctgcaa
    36961 tcacaactgt actatctaag aaaaacggcg gccaagctat ggcttacgat caaatcgatg
    37021 gtgctccaga agaacgcgaa cgcggaatca caatctcaac agctcacgtt gagtatgaaa
    37081 cagatacacg ccactacgct cacgttgact gcccaggaca cgcggattac gttaaaaaca
    37141 tgatcactgg tgctgctcaa atggacggag ctatcttggt agtttctgct gctgacggcc
    37201 caatgcctca aactcgtgaa cacatcctat tgtctcgtca agttggtgtt ccttacatcg
    37261 ttgtattctt gaacaaagta gacatggttg atgacgaaga attactagaa ttagttgaaa
    37321 tggaagttcg tgacctatta acagaatacg aattccctgg tgacgatgtt cctgtagttg
    37381 ctggatcagc tttgaaagct ctagaaggcg acgcttcata cgaagaaaaa attcttgaat
    37441 taatggctgc agttgacgaa tacatcccaa ctccagaacg tgacaacgac aaaccattca
    37501 tgatgccagt tgaagacgtg ttctcaatta ctggacgtgg tactgttgct acaggtcgtg
    37561 ttgaacgtgg acaagttcgc gttggtgacg aagttgaagt tgttggtatt gctgaagaaa
    37621 cttcaaaaac aacagttact ggtgttgaaa tgttccgtaa attgttagac tacgctgaag
    37681 ctggagacaa cattggtgct ttactacgtg gtgttgcacg tgaagacatc caacgtggac
    37741 aagttttagc taaaccaggt acaatcacac ctcatacaaa attctctgca gaagtatacg
    37801 tgttgacaaa agaagaaggt ggacgtcata ctccattctt cactaactac cgtccacaat
    37861 tctacttccg tacaactgac gtaacaggtg ttgttgaatt accagaagga actgaaatgg
    37921 ttatgcctgg cgacaacgta acaatggaag ttgaattaat ccacccaatc gctatcgaaa
    37981 acggtactaa attctcaatc cgtgaaggcg gacgtacagt tggtgccggt gtcgttacag
    38041 aaatcaaagc ttaattcact taagttttaa agtaaagcaa catttattcg gacgtaatcg
    38101 ctcggaacga aggtcttagg atctttgttc cgagcttttt tatttattgc aggatcagga
    38161 aaaaagacag gagtattata aatagaagaa acacgaaata aaagagtcag tattttctaa
    38221 atgaaacttt atgaaaacaa aatgtttttt acaagaaaaa gccttgcttt gtgagtttat
    38281 atatattata atgacaaagg tgcgtttact ttagtgaatt gcacagacgt aatcagaatg
    38341 atttcgtcgg ctaagaaacg agaggttgcg acacgcccgg acgctttgcc acgaacgagc
    38401 gtgacggaaa ttttcgtgga gctatgtcta cttttcaaaa taggcgaagg agggaacaag
    38461 atggcaaaac aaaaaattcg tatccgttta aaagcgtatg aacaccgtat tttagatcaa
    38521 tcagcggata aaatcgtgga aactgcaaaa agaactggag ctagcgtgtc tggtccaatt
    38581 ccattaccaa ctgaacgcag tctttacaca atcatccgtg cgactcataa atacaaagat
    38641 tcacgcgaac aattcgaaat gcgtacacac aaacgtctta tcgacattgt gaacccaaca
    38701 ccaaaaactg ttgatgcttt gatgaagcta gacttaccat ctggtgtaaa catcgaaatc
    38761 aaattataaa actaaaacaa aaataatgga ggtgtactca tgaccaaagg aatcttaggg
    38821 aaaaaagtgg gaatgacaca aatcttcact gaatctggtg aattaattcc agtaactgtt
    38881 gtagaagcta ctccaaacgt agtactacaa gtgaaaacaa tggaaacgga tggctacgaa
    38941 gctattcaag ttggttacca agatatgcgt gaagttttat caaacaaacc tgcgaaaggt
    39001 catgttgcaa aagcaaacac ggctcctaag cgcttcattc gtgaattcaa aaatgttgag
    39061 ctaggagaat atgaagtagg aaaagaaatt acagtagatg ttttccaagc aggagacatt
    39121 attgatgtaa caggtactac gaaaggtaaa ggattccaag gggttatcaa acgccacgga
    39181 caaagccgcg gaccaatggc tcacggttct cgttaccatc gtcgtcctgg gtcaatgggt
    39241 ccagttgcac ctaaccgtgt atttaaaaac aaacgtcttg ctggccgtat gggtggcaac
    39301 cgcgtaacta tccaaaactt ggaagttgta cgtgtcgatg cagaaagaaa tgttatcttg
    39361 atcaaaggta atgttcctgg agctaaaaaa tctttaatta ctatcaaatc agctgtgaaa
    39421 gctaaataat tgtaggaaga aaggaggaac taaggaatgc cgaatgtagc attattcaaa
    39481 caagatggaa gccaaaacgg tgaaatcaca cttaacgaag aaatcttcgg aattgaacct
    39541 aatgaaagtg ttgtttacga tgcaatcgta atgcaacgtg cgtcattaag acaaggaaca
    39601 cacgcggtta aaaaccgtag cgctgttcgc ggcggcggac gtaaaccatg gcgtcaaaaa
    39661 ggaacaggtc gtgcacgtca aggatctatc cgctcaccac aatggcgtgg aggtggcgta
    39721 gtctttggac caacaccacg ttcttacagc tacaaacttc ctaaaaaagt tcgtcgttta
    39781 gcaatgaaat ctgtattgtc agaaaaagtt gctgaaaaca acttggtagc aatcgaaggc
    39841 ttgaacttcg acgcaccaaa aacaaaagaa ttcaaacaag ttcttgctaa cttatctatc
    39901 gactctaaag tattggttgt tctagaaaaa ggtaacgact ttgctgcttt atcagcacgt
    39961 aacttaccaa acgtttctgt agtaacttct gataatgtga gtgtgctaga cgttgtatca
    40021 aatacaaaag tgttagcaac acaaactgct cttactcaaa ttgaggaggt gcttgcataa
    40081 tgaacttact agacgtaatc aaacgcccag tgatcactga aaaatcaatg cttgccatgg
    40141 atgacaagaa atacactttt gaagtggaca ctcgcgcaaa caaaacttta gtaaaacaag
    40201 cggtagaagc tgcttttgac gttaaagtca aaaacgtgaa catcgtgaac gtacgtgcga
    40261 aattcaaacg tatgggcaaa tatgcaggat atacaaaaaa acgtcgcaaa gcgatcgtta
    40321 cattgactga agattcaaaa gaaatccaat tattcgaagc tgctgaataa gcactaatag
    40381 ataactcatt aaattaggag ggaaaaacgt ggcgattaaa aagtacaaac ctacctcaaa
    40441 tggtcgtcgt aacatgacag gttctgattt tgctgaaatc acaacatcaa cacctgaaaa
    40501 atcattgtta caaccattga aaaaccatgc tggacgtaac aacaacggcc gcatcactgt
    40561 acgtcatcaa ggtggcggac acaaacgcca atatcgcgtg atcgacttca aacgtaacaa
    40621 agataacgtt gttgcaactg ttcaaacgat cgaatatgat ccaaaccgtt cagctaacat
    40681 cgcgttagta cactatgaag atggagtgaa agcttacatc ttagcaccta aaggactaga
    40741 agtgggtatg aaacttgttt caggtccaga agcagatatc aaagtcggaa atgctcttcc
    40801 attagaaaac attccagttg gtactgttat ccacaacatt gaaatgaaac ctggtaaagg
    40861 tggacaattg atccgttctg ctggtacaag tgctcaagta cttggtaaag aaggcaaata
    40921 cgtattgatc cgcttgaact ctggtgaagt tcgtatgatc ttagctgcat gccgtgctac
    40981 aatcggttct gtaggtaacg aacaacacga attaatcaac atcggtaaag ctggacgctc
    41041 tcgttggatg cgtaaacgcc caactgtacg tggtagcgta atgaacccta atgatcaccc
    41101 acacggtggt ggtgaaggta aagctcctat cggacgtaaa gcaccagttt ctccttgggg
    41161 tcaaccagct cttggttaca aaactcgtaa caaaaaagct aaatcagaca aacttattgt
    41221 tcgtcgtcgc aaaaataaat aattactttg accatgtgtc gcacattttg agaggaggtt
    41281 caccatgggt cgtagtttaa agaaaggacc ttttgtcgat gagcatttaa tgaaaaaagt
    41341 tgaagctcaa gcaggggttg aaaagaaaaa agttatcaaa acttggtcac gccgttcaac
    41401 agttttccca agttttgttg gatataccat cgcagtttat gatggacgta aacatgtacc
    41461 agtttacatc caagaagaca tggtaggaca caaattaggt gaatttgcac ctacaagaac
    41521 ttatcgtgga catgctgctg acgataagaa aacgaaacgc taatttgagg ggaggataaa
    41581 tccaaatggc agaacaaatc acatcagcta aagcaactgc aaaaacagtt cgcacttcac
    41641 ctcgaaaagc ccgtttagta attgacctta tcagaggtaa aagtgtcgca gatgcaattt
    41701 caatcttgaa attcacacca aacaaatctg ctggaatcat tgaaaaagta ttgatgtcag
    41761 cagttgcgaa tgcagaaaat aactttgact tagatgttga aaacttggta gtaagcgaag
    41821 cttttgttaa cgaaggacct acaatgaaac gtttccgtcc tcgtgcaaaa ggatcagctt
    41881 ctccaatcaa caaacgtaca agtcatatca cggtagtcgt atcagaaaaa taaggaggga
    41941 taatcagtgg gtcaaaaagt acatccaatt ggaatgcgtg taggcatcat ccgcgactgg
    42001 gatgctaaat ggtatgctga aaaagagtat gctgagttct tacacgaaga tttaagaatc
    42061 cgtaaattta tttcaactaa acttgctgat gctgctgtat caacagttga aatcgaacgc
    42121 gcaacaggtc gcgtaaacat ttcaattcac acagctaaac caggtatggt tattggtaaa
    42181 ggcggttctg aagtcgaaag cctaagaaaa gaattaaaca aattaactgg taaaagaatc
    42241 catatcaata tcgtggaaat caaaaaacca gatctagatg caaaattagt aggtgaagga
    42301 atcgcacgtc aattagaaaa ccgtgttgct ttccgtcgcg ctcaaaaaca agccatccaa
    42361 cgctcaatgc gtgctggcgc tcaagggatc aaaactcaag tatctggtcg tctaaacgga
    42421 gcagatatcg ctcgttcaga aggatactca gaaggaactg ttcctcttca tactttacgt
    42481 gcggacattg attacgcatg ggaagaagca gatacaacat acggaaaact aggagttaaa
    42541 gtgtggatct atcgtggaga aattcttcca actaaaaaaa acactgagaa aggagggaaa
    42601 taatcatgtt agtacctaaa cgtgtaaaac accgtcgtga attccgcgga aaaatgcgcg
    42661 gggaagctaa aggcggaaaa gaagtagcat tcggtgaata cggtttgcaa gctgttgatt
    42721 cacattggat cacaaaccgc caaatcgaag ctgctcgtat cgcaatgact cgttacatga
    42781 aacgtggtgg gaaagtatgg attaaaattt tccctcacaa atcttatact gccaaagcaa
    42841 ttggggtacg tatgggttct ggtaaagggg cacctgaagg atgggttgca ccagtaaaac
    42901 gtggtaaaat catgtttgaa atcgcaggcg ttcctgaaga agtagctcgt gaagcgttac
    42961 gtctagcttc tcacaaatta ccaatgaaaa ctaagatcgt aaaacgtgag gaaatgggtg
    43021 gtgaatcgaa tgaaggttaa agaaatcaga gaattaacca ctgccgaaat gcttgatcaa
    43081 gaaaaacaat taaaagaaga attgtttaat cttagattcc aattagcaac aggtcaatta
    43141 gaaaacactg cacgtattaa agaagtacgt aaatcgattg cacgcatcaa aactgtgttg
    43201 cgtgaacaag ctaagtaatt atggaaggag gccattaagc gtatgactga aggaagaaat
    43261 caacgcaaag tttatcaagg tcgcgtggtt tcagacaaaa tggataaaac aattaccgtt
    43321 gctgtcgaaa caaagaaaaa ccaccctatc tatggcaaac gcatgaacta ttctaagaaa
    43381 tacaaagtgc atgatgaaaa caacacagca aaagttggcg acatcgtgag aattatggaa
    43441 actcgtccat tatcagctac aaaacgtttc cgtttgttgg aagtagtcga agaagcagtt
    43501 attatctaat aacacgagat tttcctatat agattgaatg caaaatctga aaggaggata
    43561 cacaacgtga tccaagcaga aagtcgttta aaagtcgctg ataactcagg cgcacgtgaa
    43621 attttgacga tcaaagtcct tggtggatct ggtcgtaaaa ctgctaacat cggtgatgtg
    43681 atcgttgcta cggttaaaca agcaacgcca ggtggggttg tcaaaaaagg tgacgtcgtt
    43741 aaagccgtta tcgttcgaac aaaatcagga gctcgtcgta cagacggttc atatattaaa
    43801 tttgatgaaa atgctgcagt gattattcgt gatgataaaa gccctcgtgg aacacgtatc
    43861 tttgggccag ttgcacgtga actacgtgaa aacaacttca tgaagatcgt ttcactagca
    43921 ccagaagttt tataatcttg agacacttat caaaggaggt gcgaaacagt tatgtttgtt
    43981 aaaaaaggcg ataaagttaa agttatcact ggaaaagaca aaaacaaaga aggcgttgta
    44041 ctagcagcgt tcccgaaaaa agataaagtt attgtcgaag gtgtaaatgt cgttaaaaaa
    44101 caccaaaaac cttctcaagc tgctcctcaa ggtggaattg ttgagatgga agcgccaatt
    44161 catgtttcta acgtgatggt ggttgactct actggtgtag ctggccgagt tggctacaaa
    44221 gaagtagacg gcaaaaaagt ccgtgtttct aaaaaaaccg gtgaagtttt agataaataa
    44281 aagtttaagg aaggagggtc ttactgaatg aaccgcctaa aagaaaaata tcttaaagaa
    44341 gtaactccat cattgatgga aaaatttaac tatagctctg ttatgcaaac acctaaagtt
    44401 gaaaaaatcg tcatcaacat gggtgttggt gatgcggtat caaacgctaa aaacttagat
    44461 aaagcagttg aagaattaac tttgatcact ggtcaaaaac caatgattac aaaagctaaa
    44521 aaatcaatcg ctggattccg tttacgtgaa ggaatgccaa ttggtgcaaa agttacattg
    44581 cgcggagaaa gaatgtacga attcttagac aaattggttt ctgtttcact accacgtgta
    44641 cgtgacttcc atggtgtaag taaaaaagcc tttgacggtc gtggaaacta tactttaggt
    44701 attaaagaac aattgatctt cccagaagta gattatgatt tagtagataa agtacgtggt
    44761 atggacatcg ttattgtaac aacagcaaac tctgatgaag aatctcgtga gttgttgaca
    44821 caattaggca tgccattcca aaaataatta aaggaggcga actacgtggc taaaaaatca
    44881 atgattgcta aaaacaaacg tcctgcaaaa ttttcaacac aagcttatac tcgttgcgaa
    44941 cgttgcggac gtccacattc agtttatcgt aagttccatc tttgccgtat ttgcttccgc
    45001 gaacttgcct ataaaggtca aattcccggc gtgaagaaag ctagctggta aaaagtaaat
    45061 tcgcataaga aggaggtaaa agatcaatgg tcatgacaga tccaattgca gattttctaa
    45121 ctcgtatccg taacgcaaac atggttaaac atgagtcttt agaagtacct gcatcaaaaa
    45181 ttaaacgtga catcgctgaa atcttgaaac gtgaaggttt cgttcgtgat gttgaataca
    45241 tcgaagatga caaacaaggc gtgatccgtg ttttcctaaa atttggtaaa aacggcgaac
    45301 gtgttatcac aaacttaaaa cgtatctcta aaccaggttt gcgtgcttat gtcaaagctg
    45361 acgaagtacc aaaagtattg aacggtttag gtatcgcaat catttcgact tctgaaggtg
    45421 ttgtcactga taaagaagct cgtgaaaaaa atatcggcgg cgaagttatc gcttacgtat
    45481 ggtaatcaag tagaatctac aaggaggtgt ctttaagtga gccgtatcgg aaataaagtc
    45541 gttgttatcc ctgaaggagt aacagttact caagacggaa acaacgttac agttaaagga
    45601 ccaaaaggtg aattgactcg tactttttca gcagatatca aaatgaatat cgaaggaaac
    45661 gaagtaactt tcactcgtcc aaacgacagt aaagaaatga aaacaattca tggaacaact
    45721 cgtgcgaact tcaacaacat ggttgtaggt gtcagcgaag gtttccaaaa agcgttagaa
    45781 ctaatcgggg ttgggtaccg tgcacaatta caaggatcaa aacttgtatt gaacgttggt
    45841 tactcacatc cagtagaaat cacaccacca gctggagtaa ctgttgaagt accagctaac
    45901 acacaagtaa ttgttaaagg tgcgaacaaa gaagaagttg gcgaattagc tgcaaacatt
    45961 cgtggaactc gtcctccaga accttataaa ggtaaaggta ttcgttatgt tggcgaatat
    46021 gtacgccgta aagaaggtaa aactggtaaa taatcgttta gaaaaattgc atagaagcca
    46081 gcagcaggaa aaaggcattt ggctgaagtt taccttcaaa aaaatacatt tttacttgtg
    46141 ccgcagcttc tatttttcga aacgtattta ctgcttgaaa tagtagtaca ataaaaataa
    46201 agaggtgaca attgtgatta caaaaccaga taagaacaaa acacgtcaaa agagacatcg
    46261 tcgtgtacgt aacaatatct ctggtactgc tgagcgccca cgcttgaacg tttttcgttc
    46321 taacaaaaac atctacgctc aaattattga tgacgtagcg ggtgtaacgc tagcaagtgc
    46381 ctctaccttg gataaagaaa tttcaggtgg aacaaaaaca gaagcagcac aagctgtcgg
    46441 taaactagtt gctgaacgtg cagctgaaaa aggcattaaa gtagtagtct ttgaccgtgg
    46501 tggatacctt taccatggcc gtgtgcaagc tttagctgaa gctgctcgcg aaaatggact
    46561 agaattttag aagaaggagg aataccattc atggtttata tcgatccaaa acatttggaa
    46621 ttagaagacc gcgttgttgc aattaaccgt gtaacaaaag ttgttaaagg tggacgtcgt
    46681 ctacgttttg ctgctttagt tgttgtcggt gacaaaaacg gacacgtagg atttggtaca
    46741 ggtaaagctc aagaagttcc tgaagcaatc cgtaaagcaa ttgaagatgc gaagaaaaac
    46801 ttagttgaag tacctatggt tggttcaaca atcccacacg aagtaatcgg tgcttttagt
    46861 ggtggtagaa tcctaatgaa acctgctgta gaaggttctg gggttgctgc tggtggacca
    46921 gttcgtgccg tattagaatt agctggggta gcagatatca cttctaaatc tttaggctca
    46981 aatacaccaa tcaacgttgt tcgcgcaaca gttgaaggtt tgaaacaatt gaaacgtgca
    47041 gaagaagttg cagaacttcg cggcaaatca gttgaagaat taatcggata aggaggacaa
    47101 caataatggc tgaattaaaa gttactttaa aacgcagtat tatcggacgt cctcaaaacc
    47161 aacgcgatac agttaaagcg ttaggtctta caaagattaa cagttcagtg gttaagcctt
    47221 ctaatgaagc aattaaaggc atgatcaata ctgtttctca cctagtggac gttgaagaaa
    47281 tttaatttag aaaaatcata actagaacat taaggaggtg ccaaacctat gaaacttcat
    47341 gaattaaaac ctgctgaagg ttcacgccaa gtacgtaacc gtgttggtcg tggtacttca
    47401 tctggtaacg gaaaaactgc cggacgcgga caaaaaggac aaaaagctcg ttcaggcggc
    47461 ggtgtgcgtt taggatttga agggggacaa acaccattgt tccgtcgttt accaaaacga
    47521 ggattcacaa acgtgaaccg taaagactat gcagtcatta atcttgatgt attgaaccgc
    47581 tttgaagacg gagctgaagt aactcctgtt gctttagttg aagctggaat cgtgaaaaac
    47641 gaaaaagctg gaatcaaagt attagctaat ggggaactaa acaagaaatt aactgtgaaa
    47701 gcagcaaaat tctctaaagc agctcaagaa gcaattgaag cggctggtgg atcaatcgag
    47761 gtgatctaat gtttagacta ttaaaagatg cttttaaagt aaaagacatt agatcgaaaa
    47821 tcctatttac tgtatttgtg ttgtttgtat ttcgcctagg tgcacatatt actgtaccag
    47881 gcgtaaatgc tgcttcattg caaaaccttt cttctttgcc atttttcaac atgttgaact
    47941 tggtaagtgg tagtgcgatg caaaactttt ccattttctc aatgggggtt tcaccataca
    48001 ttactgcttc tatcgtcatt cagcttcttc aaatggacat cgtgcctcga tttgttgaat
    48061 ggtcgaaaca aggggaagtt ggtcgtaaaa aactgaatca agcgactcga tatctgacat
    48121 tagtattggc atttatccaa tctgtcggta tcactgctgg attcaatcaa tacgctcaat
    48181 taggtttcgt gaataatcct aacgtagcaa cttacgtaac gatcggtttg attctaacag
    48241 ccggtacgat gtttgttact tggctaggag aacagatcac agaaaaaggt atcggaaatg
    48301 gcgtatcaat gatcattttt gcaggtatca tttctagatt gcctgaaagt atcagagaaa
    48361 tttatgaaga ttactttata aatattgatc cttcagacat atggaaatct gctatttttg
    48421 tggccatttt actagtagcg gtcttgttga tcgtgacatt cgtaacattt ttccaacaag
    48481 ctgaacgcaa gatcccgatc caatatacga aacgcgtagc tggcgcgcct acaagcagct
    48541 atctgccgtt gaaagtaaat gcagctggag ttattccagt tatctttgct agttcgttta
    48601 ttgctacgcc aaatgctgtt ttacaagcat tgagcggtag attcggttct gaaaactggt
    48661 acaaagtgat gatggagatc tttaactata atacagcacc tggtgctacg atttatacga
    48721 ttctgatcgt tgccttcact ttcttctacg cctttgttca agtaaaccct gagaaattag
    48781 cggaaaactt gcaaaagcaa ggaagttata taccaagcgt acgccctggt aaggggactg
    48841 aagagtatgt ctcaagatta ctgatgcgtt taagtacagt tggtgcagtc ttccttggtt
    48901 tagtggcatt gcttccaatc attgctcaaa tggtttggga tcttccacaa tcaatcggat
    48961 taggcggtac aagcttactg atcgttatcg gtgtagcttt agaaactgcg aaacagttag
    49021 aaggcttaat gctgaaacgt aaatatgttg gattcattga gtaagaaagc gtgttgaggt
    49081 ttcccctcaa cacacgttct cacacattta ttaggaggga aaacaatgaa cctcatttta
    49141 atggggctgc caggcgcagg taaaggaaca caagctgaaa aaatcattga tgcttatggt
    49201 attccgcaca tctcaacagg agatatgttc cgcgcagcga tgcaaaacga aacagctctt
    49261 ggcctggaag caaagtctta tatggataaa ggtgcattag ttcctgatga agtaacaaat
    49321 ggaatcgtga aagagcgact agctgaacca gatacagaga aaggcttctt attagatggc
    49381 tttccacgta cgctagatca agcaaaagct ctggacgcaa tgctaaaaga tttgaataaa
    49441 aaaattgatg ctgtcatcga tatccatgtt ggtgaagaaa tcttggtcga acgtctagcc
    49501 ggccgattta tctgcagcaa ttgtggagca acttaccata aaattttcaa ccctacaaaa
    49561 gttgaagaca catgtgatcg ttgcggtggg catgaattct atcaaagaga agatgataaa
    49621 cctgagacgg ttaaaaatcg tctggctatc aacatcaaaa atagtgaacc aatcttggct
    49681 tattataaag aacaaggttt gctaaacact attgatggtg ctcgtgaaat cgatgctgta
    49741 tttgcagatg tacaaaaaat cattgaaaaa tagcacgatt gcccgtagcc gacttgcatt
    49801 atgcagttac tcttgtcaag ttcaataaat tatgatagaa tatgtcagtc cgacttctag
    49861 agaatcctct agatgatcca ttttgagaat tttgaggtgg gaactgcagt ttccgccatt
    49921 ttatcgtgtg aaaatgcgaa acaagtacaa ggaggtactg tgcgtggcaa aagaagatat
    49981 gattgaagtc gaaggtacag tcgtcgaaac tttgccgaat gcaatgttta aagttgaact
    50041 agaaaacgga caccaagttc ttgctactgt ttcaggtaaa attcgtatgc attacatccg
    50101 tatcttacct ggtgacaaag taacggttga attgtctcca tacgatctta accgtggccg
    50161 tattacttat cgctttaaat aattgtactc cgtaaaacta caggaggtat tatcatgaaa
    50221 gtaagaccat cagtaaaacc aatgtgcgaa cattgtaaag taattcgtcg taaaggacgc
    50281 gttatggtga tttgcccagc aaatccaaaa cataaacaac gtcaaggata attggaggtg
    50341 ctataaatat ggctcgtatt gcaggagtag atattcctcg tgataaacgt gtagtagttt
    50401 cacttactta tatctatggt attggtaaca ctactgctaa aaagatctta gctgatgctg
    50461 gtgtatctga agatgttcgc gttcgtgaat taacgaatga acaaacagat gctatccgtg
    50521 cagaagtaga taaattaaaa gttgaagggg atcttcgtcg tgaagtgaac ttgaacatca
    50581 aacgtttgat ggaaatcggt tcttaccgtg gaatccgtca tcgccgtgga ttgcctgttc
    50641 gtggacaaaa cacgaaaaac aatgcacgta ctcgtaaagg cccagctcgc gctatcgctg
    50701 gcaagaaaaa ataattctta agtgaaggag gttaaaactt catggcagca aaaaaagtga
    50761 atcgtaaacg ccgtgtgaag aagaatatag aagcaggtat tgcacatatc cattctacat
    50821 tcaataacac tatcatcatg atcactgata ctcacggaaa tgcattagcg tggtcatcag
    50881 ctggttcatt aggtttcaaa ggaagcaaaa aatcaactcc ttttgccgct caaatggcag
    50941 cagaaactgc tacaaaagca gcaatggaac acggattaaa gactgttgaa gtaacagtta
    51001 aaggacctgg ttctggacgt gaagcagcaa ttcgttcatt acaagctaca ggtttagaag
    51061 tgactgcaat tcgtgacgtg actccagttc ctcataatgg tgcccgccct ccaaaacgcc
    51121 gtcgtgttta atgagtgccg ctcattttga gttttatcag taacgtcatt gaacaagaca
    51181 cttttcgttt tgaaaggggt aaagataaga atgattgagt tcgaaaaacc aagaatcgca
    51241 aaaattgatg aagaaaaaga ttatggcaag ttcatcgttg aacctcttga aagagggtat
    51301 gggactactt tagggaattc cctacgtcgt attttattat cttctttgcc aggtgctgcc
    51361 atcactaata ttcaaatcga tggtgtactg catgaattct ctaccatcaa aggtgttaga
    51421 gaagacgtca ctcaaatcat cttgaacatt aaaggcttag cgctgaaaat gtatggccaa
    51481 gaagaaaaaa cccttgaaat cgatattacc ggacctgcta cagtaactgc tggcgatatt
    51541 atcgttgata gtgatgtaga aattcttaac aaagatatgt acatctgtag tgtctctgaa
    51601 ggagctacgt tccatgctcg cttaacagtg aaacctggac gtggttatgt tcaagcagat
    51661 gaaaataaaa aagaagatat gccaattggc gttcttccag tcgattcaat ctacacacct
    51721 gttcgtcgtg tgaactatca agttgagaac acacgtgttg gacaccgtga agattttgat
    51781 aaattgacga tggagatttg gacagatggt tcaattgaac cgttggaagc aatgagtttg
    51841 tctgcgaaaa tcatgactga acatttggat atttttgtga acttaactga tgaagcaaaa
    51901 aatgctgaaa tcatggtcga aaaagaagaa acacaaaaag aaaaaatgtt ggaaatgacg
    51961 atcgaagagt tagacttgtc tgttcgctct tacaattgtt tgaaacgtgc aggaatcaat
    52021 actgtacaag aacttacaaa taaatctgag cctgaaatga tcaaagtccg taacttagga
    52081 cgtaaatcat tagaagaagt taaagcaaaa ttgcacgact taggtttagg tttacgtaaa
    52141 gaagattaaa accttttacg aaggagggaa accaacgtga gttatcgtaa actaggacgc
    52201 acatctagcc aacgtaaagc gatgttgcgt gatttaacaa ctgatttatt aatcaacgaa
    52261 cgtattgtga ctactgaagc tcgtgcgaaa gaagttcgct caactgcaga aaaaatgatc
    52321 actttaggta aacgcggaga tttgcatgca cgtcgtcaag ctgcggcttt cgtacgtaat
    52381 gaagttgcca gcgtgcgtga agaaaatgag gacatcgtca ttgaatcagc tttacaaaaa
    52441 ctgttcaacg atattgcacc tcgttacgca gaacgtcaag gcggatacac acgcattttg
    52501 aagacagaac caagacgcgg tgatggtgca ccaatggttg tcttagaact tgtctaaaat
    52561 cacactaata acatcacttt atagatgatt cttttagagt gttatgatgt tggaagatat
    52621 ttttccgagt ctagctcagc gctgctcctc aagcgaatat cgcttgggga gtaagcactc
    52681 atcataaagt gtttttttat accttcaatt acctgtcatg acagatatgt ttgaaggcat
    52741 aaaaaaacat tttaagcgag aaataattga aaattttgtc tttttttgat agtgttagta
    52801 ggaactttag gatgaagaag gagtaatcat ggagccaatt attgaattag aaaagataaa
    52861 ttataaatac cagccagatg atcttcgccc cgcattgaaa gatgtctcct ttacaattga
    52921 taaaggtgag tggatcgcta ttattggaca caatggttca ggaaaatcga cacttgccaa
    52981 aacgatcaat ggattgcttc tgccagaatc agggatcgtg aaagtgggaa atcaaatatt
    53041 ggatgaagaa aatatttgga cgatccgaca gatggttgga atggtttttc aaaatccaga
    53101 caatcagttt gttggttcga cagtagaaga tgacgttgct tttggtcttg aaaatcaagg
    53161 gattcccaga gaagaaatgc tagtgcgtgt gaaagatgca cttgagaaag ttagaatggc
    53221 tgagtttgct tcacgcgagc ctgctcgttt atcaggaggg caaaaacaac gtgttgccat
    53281 tgccggcgtg gttgccttac gacctgatat cattatttta gatgaagcaa ccagtatgct
    53341 agatccagaa ggtcgtgaag aagtgatctc tacgatcaag aagatcaaag aagaaagtca
    53401 attgaccgtt atatctatca ctcatgatat tgatgaagca gctaatgcca atcggatact
    53461 agtgatgaga caaggcgaac ttgtccgtga aggtacacca aaagaaattt tttctgctgg
    53521 tcctgaactg atcgacttag gtctagatct accatttcct gaaaaactga agagcgcact
    53581 gaaagaacgt ggggttgatg tgcccagtga atatatgaca gaagaaagga tggtggattg
    53641 gttatggaca tccgttttga acaagtagac ttcacttatc agccgaatac accatttgaa
    53701 caaagagcct tatttgacat caatatgacg atcaaagaaa acagttatac tgcattagta
    53761 gggcataccg gaagcgggaa atcaacctta cttcagcatt tgaatgcgct tgttaagcca
    53821 acaagcggta cagtccatat tggagaacga gatattcagc cggatacgga taataagaat
    53881 ttaaagccca tccgaaaaaa agttggcatc gtctttcagt ttccagaagc acagctattc
    53941 gaagaaacgg tagcaaaaga cattgctttc ggtcctaaaa actttggtgt cagcgaagaa
    54001 gaagcactag tcctagcaaa agaaacatta gaacaagttg ggctggatga aagctatttg
    54061 gaacgttcgc catttgaact ttcaggaggg caaatgcgta gagtagcaat cgctggtgtg
    54121 cttgccatga ggccggaagt acttgtattg gatgaaccaa cggcaggact tgatccccag
    54181 ggcagaaaag aaatgatgga gatgttttgg cgtcttcata aggaacagca gatcactatt
    54241 gtattagtta cgcatttaat ggatgatgta gccaattttg cagattatgt ctatgtgttg
    54301 gaaaagggac gaatcgttaa tagcggggag ccgcaagagg tctttcaaaa cattgaatgg
    54361 ctaaaagaaa aacaactagg cgtacctact gccaccgagt ttgcagaaga attaatggct
    54421 aaagggatga actttgctac cttgcctttg acagctgaag aattagcaga cgctatcgtc
    54481 cattatgctg gaggaaatgc ccatgatgaa taaattgata tttggtcgtt atatgcctgg
    54541 agattccttg atccatcgat tggatccccg agctaaatta ttagccagtt tttattttat
    54601 cggaatcatt tttttagcaa ataattggga aacgtacctt ttgttggcat ttttcacatt
    54661 actttctgtc ttcttgtcaa aagtagattt gaaatttttt atccgaggca ttcgcccatt
    54721 gatctggcta atcctcttca ctgtagcttt gcaggtcttg tttacaagtg gcggagaaac
    54781 ttattggagt tggggtgttt tccatatcac tgaatttggt gtgatgaacg gcctctttat
    54841 tttctgtcga ttcgtgttga tcatttttat gtcgactcta ctcacgctta ctacaccgcc
    54901 tttggaatta tcggatgcga ttgagtactt gcttcgtcca ttgaaagccg tacggttccc
    54961 agtccacgaa atttcattga tgctgtcgat tgctcttcgt tttgtgccta cattgatgga
    55021 cgaaacagaa aagatcatga acgctcagcg cgctcgcggt gttgattttg gtgaaggaaa
    55081 cctagttcag aaaatgaaag cagtcattcc tttgctgatt cctttatttg tcagcagctt
    55141 caaccgtgcg gaagatcttg cgactgctat ggaagcaaga ggctacaaag gtggggaagg
    55201 aagaacgaaa tatcgtgtat tgcattggca taatagagac acgatggtta tcattgcttt
    55261 tgtattatta actgtgctac tgatcttttt aagaggataa acgttcagtg ggccgctatc
    55321 tattcttttc ttgctgatct gtttgcaaga aaggatgcaa gcagtgtatg acaagaaata
    55381 ttagggtctg tggcagacta aggtcacagg cctctttctt ttatctgaaa agaaagaacg
    55441 aaaaaatttt atagaaaaat cattattcca gataaccttt taggaacaaa ggagagaaaa
    55501 acatggtacg ttacaaagca atcattgcgt acgacggaac aaattttaat ggattccaaa
    55561 aacagccaaa tgggcgtact gttcaagaag aagtagaaaa aacattacaa aaaatggcaa
    55621 atggaaaaga aatcacggtc tttggttcgg gaaggacaga tgccggagta catgcgatcg
    55681 ggcaagtaat ccattttgat tatccagagg agcgtccgtt agaacgaatg cgtttcgcgc
    55741 tagataccca gtcaccagag gatattgctg taagacaagt agaaattgtt tcagaagact
    55801 tccacgcaag atatttggtc aaagaaaaga cgtatcaatt tcgagtggat atagggaaac
    55861 cacgcagtcc ttttcgacgc cattatgcaa gttattttcc ttacccactt gatttggaaa
    55921 aaattcagcg ggcgcttcct gatttattag ggactcacga tttcacctct ttttgtgcat
    55981 caggaagctc gatagaggat aaaatacgta cgatctacga ggctaagatg gaggtaaatg
    56041 aaacaaaaga cgaattgttg tttacattta ggggaaatgg cttcttgtat aagatgatac
    56101 ggatcttagt aggaacgctt ttgaaaattg gcaatggccg attgcctgaa gatagtatcc
    56161 cagatattat tgcgaaaaaa gatcgtaatg cagcaggacc tacagcacac cctgaaggac
    56221 tttatttgta tgaagtgaaa tatgaataag aggttatgat agaagtggtc agcttcaaga
    56281 aataagaagg tatttacgaa aattacttct caaaattttg caaaatttcg gcttattttc
    56341 gaagaagcta cttctggaac accgtttaag gaagaggtcg tgaaatcagc gttttgacct
    56401 gagtattaga gaaacaaacg ggaaaatagc tcctcatatt ttgccgtttg ttgagctaat
    56461 accgaaggtc agctgattga acaccgttta agaaagaggt cgtgagcctg tcatttaact
    56521 ctgagtcaca aagagcaatt tcaaaaaaca gcttctcatc tttgatgaat atcgtgactt
    56581 gtggacgagg cgttgataag tgaatcatct ttttgttacc tattttttct gtaaccaaaa
    56641 aacgatggaa cgttgttttg attgcccttg gtgcggacag tctgaacagg ttccatcgtt
    56701 tctttatttt ctacgtcttc ttctgtgtgt gtttcgtggt tgttcttcta ttgctggatc
    56761 aatcgtgcca taaaaggggc gattgcggtc aaggtaccag acataaagaa taaacaatgc
    56821 aatacatagg acaaaaagga ttgcacctat cgtaaatcct tcaggcaagt aactgaaagt
    56881 gacagtatgt ttacctgctg gaacttttat catcaagaat gcgtctttga aattgctgac
    56941 cttgactggt ttcccatcaa ttttagcttt ccatcctttg tcataaggaa tagttgtcac
    57001 caacatggaa tcttcagcgg tatttacagt cccagaagct tttctgccag tggcttccat
    57061 ttcgacacct ttttctttga tctgattcat tgcggcttga taggctacaa catctagacc
    57121 aacgacttta ggctccatga aacttatttc tttcgtccca taaaaacttg cagtaaatgt
    57181 cactgttgtc tcttgaggat aatagccaag atcatagtat tgaccagaaa tgttgatttg
    57241 cgtttttcgc gatgtaccat tgacagtgat cgtcgcacta gaactttcta attgcgcaaa
    57301 attggttggg aacaaactta agtaagcttg tgtatttgca ggcacatgga cttcccaagt
    57361 gagctctttt ggctggttat ctgctgtttc tgagtaagtg acgccagtcg ttgtctttgt
    57421 gatcgtcgta ttcaactgat tcttcaaagt aggtgtatag aatgtaaaat actgttcatt
    57481 tagaccagac aatgtattga tcaagtttgt ctgactggtc aaattatctg tcactggctg
    57541 ctcaacatca ttaacggaca acggtgcagt aaatgctagt ggcaatgcat tgacattctg
    57601 atacagtgta tagtcgccgc tttgaccagc ttggcggaag ccatatttac tgaacgtgct
    57661 ttcgttttta gaaatgttat atttgattcc tgtaaaccca tccatcagca aagtattatt
    57721 gttataacgg atattcaaat ttgtccctct tgaacggaaa cctaatttat ccaggtaaga
    57781 ggaagaatta cgatttctta tagaagaaaa caaactgata ccactgtaac catagttgat
    57841 cgaatcgttt gcagatactg gatccagatt ttccaagcgg taaaacgagt cggaatcttt
    57901 ttttgtttca tttacaagag ctttcaagtc aggataagga tcagtatata aactgcggga
    57961 agcataattc caatcatcaa gaatgccatg gatcatactg ttcgtattga ccagtgcttc
    58021 agcagacatg atcaataata acaatatact cagatgattg aatgaaagtt ttttatgctg
    58081 ataaaatccc acagcaaaag cataaatccc taagaaaacc actgtcaata caaaggaagt
    58141 catcgtcaca taggtgtagc ttccttcagg tttgatgccc catgccaccg caaagagagc
    58201 agctacgacc aaaatgattc ctaacaacag cccacgatcg tcttgttcta tcttttccca
    58261 tccttttcct gcaagcagga gcactaagaa agagaacaga taggcataac ggaataaaaa
    58321 catattcggt gcatgcatac catgccagaa caaattcaat ggaacaagat aaaaacttgc
    58381 gataagtatg gcgaaaagac tgccgtacaa aaatttattt ttcaacggta ctttccgact
    58441 ggcaaaataa aacagacaga ggactaatgg tagcagacct gcgtaaacga acggaatcga
    58501 tccgtatttt gtcgtgtcat aaacaccaat catatttttc atgattagat ccagataaga
    58561 agtcgcttct gttttcaacg tagtgatctg actcagtgcc tcgccatttg accgaagatc
    58621 cagcactgct ggcaatacaa tgatcattga agcgccgcct gccagtaaag aagtgatacc
    58681 ataaggaaca atcgtttttt tatattctga ccagtttgtc aatagacggg cgataaaata
    58741 taagaaagaa aatacgccaa tcataaaacc catataaaaa ctggataaaa acaagagtaa
    58801 ataactgata aataaaagtt tcggccgttt aagatccata acacgatgaa tccccaaaat
    58861 cactaatgga agataaaaaa atgcatccag ccacatgatg atctccgaat gtgcagtgat
    58921 aaatgagatc aatgcgtaac tgacgctaag tgcaacatgc ccccagcgag gaatcttgaa
    58981 cgtacgtgca agaaaccaaa aagccaatcc ggcacagccg accttaagca aagtcagaac
    59041 atacagtgca tctggcatca tctggtttgg aaaaaagaac accagtggcg tgaagatccc
    59101 gcctagatag taagaaatta aagataaata attcaatcct agagaagcat tccatgtata
    59161 aaaaatactt tgctttccaa gaagaacatt tcggaagctg gcatgaaaat tagaaaactg
    59221 tgaaaaggca tcacttgcca aaatacttct gctgcttcca ggatagattc cgatacttag
    59281 ataaacaagt gctaaaatca aaaacggaat caggaaacta gctgctgcgt agcgtccgtt
    59341 ttctctaaag aatgacttta aatttttttt catatttatt ttccaccaaa tttctatgaa
    59401 gttgtattca gtttatcata tccttgtttt tctctgctta aaaagagtct agttttcaca
    59461 aaaaaataaa atttagaata aataacttca taatttgttc gtataacaaa aataaacgca
    59521 aaaaaagggt aggaatcaaa agtcccaccc ttaaaaattt ttattaaata aaaaaccgtt
    59581 cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc ctgatttcaa
    59641 agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc gaactttttg
    59701 taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt tgtttccact
    59761 ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct cctttgcctt
    59821 gatttggagc aatagaataa ttcagctcat accagactaa catatcatat agaatgggaa
    59881 tttgcaagta cattttcata gatacaattg acaattgaga agaataattg taaattaaac
    59941 aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc cttttatttc
    60001 aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc cgttaaggag
    60061 gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt accaatgatg
    60121 taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta ggaatggcca
    60181 gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat tactcaagag
    60241 gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg attatcagct
    60301 atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa tacaatctag
    60361 aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt gttcgtgtac
    60421 tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg aggattatct
    60481 aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag gcaggtgcga
    60541 atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct gtgccagatg
    60601 gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca gtagtagatt
    60661 caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg ctgatgggtg
    60721 cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct aagcaaattc
    60781 cagatgttgt ctcattaaat gcttctgatc ttgctgcagc cttcactcat ggagttgaaa
    60841 ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta gctagagaag
    60901 cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa gtaatgacag
    60961 ctgttgtaaa aggagcaaag cgtgctttag ctaaaactcc agacttgctt ccagtcctaa
    61021 aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat gagggctttt
    61081 taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct ccagcagaaa
    61141 tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg gcgacagaag
    61201 atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga cctacagtcg
    61261 atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga gattctttac
    61321 ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac ccaggagaag
    61381 tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac aacatgcgct
    61441 tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg aaaaaagaaa
    61501 taccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc caagagctgt
    61561 ttgaaagttt aggcgctaat tatgttatca gtggtggaca aacaatgaat ccaagtacgg
    61621 aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc ttgccaaaca
    61681 ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc ccagtagcag
    61741 ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc aatgatcaag
    61801 cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt gtgagcggtc
    61861 aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa gaaggagact
    61921 ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca gcaacagcgt
    61981 taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc ttggcaggtg
    62041 atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa aaacatcctg
    62101 atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta ttttctgctg
    62161 aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa ggccttcggt
    62221 tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taaaggaggg aggaaaaatt
    62281 tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa aaagagcagc
    62341 tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt atccttttcg
    62401 ctacgaagat attcaggaaa gaaatctaaa cgagatccag gatcaagaaa aggttacttt
    62461 gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa aaagccgatt
    62521 gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta atcaacctta
    62581 tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat gggatgcaaa
    62641 gcgtaaagcc ttgaacggga tgaagatttt aggttctcaa acaatggatg acttttcgcc
    62701 gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa tcaaaaaagg
    62761 gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg tggagaaata
    62821 tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag accacgaaga
    62881 aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc aaatgcgtct
    62941 tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc tttatgatgt
    63001 ccaaaaattg aaacaattta ctcaaaagct accttttgaa ctgacaaatg cacaaaaacg
    63061 tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc gacttttgca
    63121 gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg ctaccgttac
    63181 agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac aacatatgga
    63241 aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgatta cggggtcaac
    63301 gaaagcaaaa gaacgacgtg agctccttga aaaactagag caaggggaaa ttaacgtcgt
    63361 gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag gtctagttat
    63421 tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg aaaaaggctg
    63481 gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag ctattacagc
    63541 atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta tcccgatcga
    63601 aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga aaaaagaact
    63661 ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag aagcattaga
    63721 tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac caaaatatga
    63781 agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca tggaagcctt
    63841 caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag gggtaaacgt
    63901 gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg cacagctgca
    63961 ccaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct tagttgctaa
    64021 tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca ccaatggttt
    64081 tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg gcttccgtca
    64141 atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg ttttggaggt
    64201 agccagagaa gaggctgcag ccctttggca aataaaggat tggcagatgc ttcctgagta
    64261 tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt tcgattagca
    64321 gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga aaattgccgt
    64381 agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg ctttagcgca
    64441 gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa tcaagaaata
    64501 cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca atagtgatga
    64561 tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg ctgcacaagc
    64621 agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg cgctactagc
    64681 agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct tgatgtctac
    64741 cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg gcgctaacgc
    64801 agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt atgcacgtaa
    64861 agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag aagcaacaaa
    64921 aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa gcttgaattt
    64981 tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag tggtcacaga
    65041 tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga atatgatgaa
    65101 tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg ctatgctttt
    65161 aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg gcggtgccgt
    65221 tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc ccgatgctgt
    65281 tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg gacaattagt
    65341 cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcgatc cgttccattg
    65401 aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt aggtaattga
    65461 caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt aacaaagtag
    65521 cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat gaattgaaca
    65581 tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta gagcttgaag
    65641 atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca gtcggtggcg
    65701 cagtagatta tatcagcagc catcttaaat aat
//
LOCUS       DAXLPY010000008        61608 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.008, whole genome shotgun sequence.
ACCESSION   DAXLPY010000008 DAXLPY010000000
VERSION     DAXLPY010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.008"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            79..831
                     /locus_tag="ACF3UF_000589"
     CDS             79..831
                     /locus_tag="ACF3UF_000589"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3670744.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(853..2007)
                     /locus_tag="ACF3UF_000590"
     CDS             complement(853..2007)
                     /locus_tag="ACF3UF_000590"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFD3670745.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            2192..4633
                     /locus_tag="ACF3UF_000591"
     CDS             2192..4633
                     /locus_tag="ACF3UF_000591"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFD3670746.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(4963..5667)
                     /locus_tag="ACF3UF_000592"
     CDS             complement(4963..5667)
                     /locus_tag="ACF3UF_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670747.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(5854..6099)
                     /locus_tag="ACF3UF_000593"
     CDS             complement(5854..6099)
                     /locus_tag="ACF3UF_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670748.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(6116..6967)
                     /locus_tag="ACF3UF_000594"
     CDS             complement(6116..6967)
                     /locus_tag="ACF3UF_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFD3670749.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            7133..8137
                     /locus_tag="ACF3UF_000595"
     CDS             7133..8137
                     /locus_tag="ACF3UF_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFD3670750.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(8378..8734)
                     /locus_tag="ACF3UF_000596"
     CDS             complement(8378..8734)
                     /locus_tag="ACF3UF_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3670751.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            9102..10289
                     /gene="tuf"
                     /locus_tag="ACF3UF_000597"
     CDS             9102..10289
                     /gene="tuf"
                     /locus_tag="ACF3UF_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFD3670752.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(10477..13068)
                     /gene="mprF"
                     /locus_tag="ACF3UF_000598"
     CDS             complement(10477..13068)
                     /gene="mprF"
                     /locus_tag="ACF3UF_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFD3670753.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(13094..13855)
                     /locus_tag="ACF3UF_000599"
     CDS             complement(13094..13855)
                     /locus_tag="ACF3UF_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3670754.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            14022..14654
                     /locus_tag="ACF3UF_000600"
     CDS             14022..14654
                     /locus_tag="ACF3UF_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFD3670755.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            14713..15573
                     /locus_tag="ACF3UF_000601"
     CDS             14713..15573
                     /locus_tag="ACF3UF_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFD3670756.1"
                     /translation="MEKRQKMENQKVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            15758..18073
                     /locus_tag="ACF3UF_000602"
     CDS             15758..18073
                     /locus_tag="ACF3UF_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3670757.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            18255..20096
                     /gene="dnaG"
                     /locus_tag="ACF3UF_000603"
     CDS             18255..20096
                     /gene="dnaG"
                     /locus_tag="ACF3UF_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFD3670758.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            20120..21229
                     /gene="rpoD"
                     /locus_tag="ACF3UF_000604"
     CDS             20120..21229
                     /gene="rpoD"
                     /locus_tag="ACF3UF_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFD3670759.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            21446..23587
                     /locus_tag="ACF3UF_000605"
     CDS             21446..23587
                     /locus_tag="ACF3UF_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFD3670760.1"
                     /translation="MMKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDA
                     AMQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIE
                     KNEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHRED
                     TKEEHAKELLKMISEKIAQENKVEPEHEAEKDTEKDISGVNAAGKESLKTNDLKTNDL
                     KTDIPEKTETLSEKQSEDEKSNGLPEADKKEMLEKADKKATESDGINNEADAETQSAS
                     EDSTALEAKIEKEENQPELIEAETEPITIVPNTEKTPQESNPEKKDLDKTQKKKSKKV
                     PYLALAAVLLLGGGGWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFI
                     RADMIHQDLSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDH
                     LADDIKLKADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVV
                     DSATRDQYKTAKEAVEKVKNTDLSAQLNEQLQQVDKMLTDKEKKEEEEKKKAEEAKKA
                     EKAKKAAEEQAKQAAQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARAS
                     DIADASNPAWTWAPGVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKS
                     ALMKGIGESALPFYIVTINCKTGWFGGNGSN"
     gene            23783..24646
                     /locus_tag="ACF3UF_000606"
     CDS             23783..24646
                     /locus_tag="ACF3UF_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFD3670761.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            24751..25224
                     /locus_tag="ACF3UF_000607"
     CDS             24751..25224
                     /locus_tag="ACF3UF_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFD3670762.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            25320..26207
                     /gene="xerD"
                     /locus_tag="ACF3UF_000608"
     CDS             25320..26207
                     /gene="xerD"
                     /locus_tag="ACF3UF_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFD3670763.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            26226..26597
                     /locus_tag="ACF3UF_000609"
     CDS             26226..26597
                     /locus_tag="ACF3UF_000609"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3670764.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGVYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            26594..27364
                     /locus_tag="ACF3UF_000610"
     CDS             26594..27364
                     /locus_tag="ACF3UF_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFD3670765.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            27348..27917
                     /gene="scpB"
                     /locus_tag="ACF3UF_000611"
     CDS             27348..27917
                     /gene="scpB"
                     /locus_tag="ACF3UF_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFD3670766.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISFEEDVSPDLFFDGMNKGE"
     gene            27923..28639
                     /locus_tag="ACF3UF_000612"
     CDS             27923..28639
                     /locus_tag="ACF3UF_000612"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFD3670767.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      28721..28845
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            28968..29579
                     /locus_tag="ACF3UF_000613"
     CDS             28968..29579
                     /locus_tag="ACF3UF_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3670768.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIP
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            29957..31480
                     /locus_tag="ACF3UF_000614"
     CDS             29957..31480
                     /locus_tag="ACF3UF_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFD3670769.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            31717..33057
                     /locus_tag="ACF3UF_000615"
     CDS             31717..33057
                     /locus_tag="ACF3UF_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFD3670770.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            33211..33948
                     /locus_tag="ACF3UF_000616"
     CDS             33211..33948
                     /locus_tag="ACF3UF_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3670771.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGNSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(34113..34334)
                     /locus_tag="ACF3UF_000617"
     CDS             complement(34113..34334)
                     /locus_tag="ACF3UF_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFD3670772.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            34365..35396
                     /locus_tag="ACF3UF_000618"
     CDS             34365..35396
                     /locus_tag="ACF3UF_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3670773.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYERILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            35383..36786
                     /locus_tag="ACF3UF_000619"
     CDS             35383..36786
                     /locus_tag="ACF3UF_000619"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFD3670774.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGFLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVIHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            36852..37487
                     /locus_tag="ACF3UF_000620"
     CDS             36852..37487
                     /locus_tag="ACF3UF_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFD3670775.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            37536..38216
                     /gene="cmk"
                     /locus_tag="ACF3UF_000621"
     CDS             37536..38216
                     /gene="cmk"
                     /locus_tag="ACF3UF_000621"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFD3670776.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            38351..39580
                     /gene="rpsA"
                     /locus_tag="ACF3UF_000622"
     CDS             38351..39580
                     /gene="rpsA"
                     /locus_tag="ACF3UF_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFD3670777.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            39762..41072
                     /gene="der"
                     /locus_tag="ACF3UF_000623"
     CDS             39762..41072
                     /gene="der"
                     /locus_tag="ACF3UF_000623"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFD3670778.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            41315..41590
                     /locus_tag="ACF3UF_000624"
     CDS             41315..41590
                     /locus_tag="ACF3UF_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFD3670779.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            41825..42871
                     /locus_tag="ACF3UF_000625"
     CDS             41825..42871
                     /locus_tag="ACF3UF_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670780.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            42873..44132
                     /locus_tag="ACF3UF_000626"
     CDS             42873..44132
                     /locus_tag="ACF3UF_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFD3670781.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            44138..44719
                     /locus_tag="ACF3UF_000627"
     CDS             44138..44719
                     /locus_tag="ACF3UF_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFD3670782.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(44801..45676)
                     /locus_tag="ACF3UF_000628"
     CDS             complement(44801..45676)
                     /locus_tag="ACF3UF_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3670783.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            45824..46156
                     /locus_tag="ACF3UF_000629"
     CDS             45824..46156
                     /locus_tag="ACF3UF_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFD3670784.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            46268..47476
                     /locus_tag="ACF3UF_000630"
     CDS             46268..47476
                     /locus_tag="ACF3UF_000630"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFD3670785.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            47630..48085
                     /locus_tag="ACF3UF_000631"
     CDS             47630..48085
                     /locus_tag="ACF3UF_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670786.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            48447..48722
                     /locus_tag="ACF3UF_000632"
     CDS             48447..48722
                     /locus_tag="ACF3UF_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670787.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            48735..50813
                     /locus_tag="ACF3UF_000633"
     CDS             48735..50813
                     /locus_tag="ACF3UF_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFD3670788.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            50976..52859
                     /locus_tag="ACF3UF_000634"
     CDS             50976..52859
                     /locus_tag="ACF3UF_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3670789.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            52871..53818
                     /locus_tag="ACF3UF_000635"
     CDS             52871..53818
                     /locus_tag="ACF3UF_000635"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFD3670790.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            53838..54365
                     /locus_tag="ACF3UF_000636"
     CDS             53838..54365
                     /locus_tag="ACF3UF_000636"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFD3670791.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(54428..55081)
                     /locus_tag="ACF3UF_000637"
     CDS             complement(54428..55081)
                     /locus_tag="ACF3UF_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFD3670792.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            55213..56055
                     /locus_tag="ACF3UF_000638"
     CDS             55213..56055
                     /locus_tag="ACF3UF_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3670793.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            56213..57109
                     /locus_tag="ACF3UF_000639"
     CDS             56213..57109
                     /locus_tag="ACF3UF_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD3670794.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            57112..57825
                     /locus_tag="ACF3UF_000640"
     CDS             57112..57825
                     /locus_tag="ACF3UF_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFD3670795.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            57845..58363
                     /gene="msrA"
                     /locus_tag="ACF3UF_000641"
     CDS             57845..58363
                     /gene="msrA"
                     /locus_tag="ACF3UF_000641"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFD3670796.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            58360..58587
                     /locus_tag="ACF3UF_000642"
     CDS             58360..58587
                     /locus_tag="ACF3UF_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFD3670797.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            58739..59290
                     /gene="lepB"
                     /locus_tag="ACF3UF_000643"
     CDS             58739..59290
                     /gene="lepB"
                     /locus_tag="ACF3UF_000643"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD3670798.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(59373..59915)
                     /locus_tag="ACF3UF_000644"
     CDS             complement(59373..59915)
                     /locus_tag="ACF3UF_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFD3670799.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(60152..60550)
                     /locus_tag="ACF3UF_000645"
     CDS             complement(60152..60550)
                     /locus_tag="ACF3UF_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3670800.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            60822..>61608
                     /locus_tag="ACF3UF_000646"
     CDS             60822..>61608
                     /locus_tag="ACF3UF_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3670801.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGL"
BASE COUNT        20874 a        10626 c        12800 g        17308 t
ORIGIN      
        1 agagatagaa tagataaaag aggagaataa tttattccga aaagtgaaaa catataacaa
       61 aaaattagag gaaatcaaat gaatgaaaaa gaatgggatg aatttgctga agaatattat
      121 gaaatccagc aagaatcgca agtaactatt gctgaagatg taaaaaatta tctgaaaacg
      181 gagaaagtcc tgcctgctga aacagcagca gacgttgctg gaggatctgg cagatttctt
      241 tccttagcaa aagaaattaa tcgctatgat ttgatcgatt tttcttcagg aatgctagaa
      301 aatgcaaaaa aagaagcaga aaaaaatgag ttgccaaatg tttcctttat caaacagtcg
      361 ttagaagaat ttatccaatc aaatgagaca tatgaaatgg tttttacagc agcaaatcca
      421 gcattggtac atcttattca attagaaaaa ttgatgaaaa agtcaagcaa atggtgcgtg
      481 ataatcaggg tagtggaatc aatcgatgat gttttttatc ctatcgaaaa gcaactagga
      541 atgatagaag aagatcctaa tacatcgcca gttgtaatgg atcaatttga aacatactta
      601 attgatgaag gattcaaagt gaagaaaaaa gattttactt attttacaca ggaatcaatt
      661 actgaagaat tgatgaagct atactatgac gcgtacgcaa aagatcctgt tgtgaccagg
      721 tacattcgca aactattcag tgaaaaacga gaaatcctta gtacgactaa gctgacctat
      781 agactgctcc tttggtccgc agataaaaaa agaacctttc acgactcgtg aagggttctt
      841 tttatgattt tattatattt tgtagtaacg aatatcattt tcgatctttg taatcgaaaa
      901 aggtacatct gaagtatatt ctgcacattc tccgtgttca ggaagcgtct cactgaaaat
      961 cgtttcatat tcgtcaacag tgatccgtgt tcgagaatct agcatctctt gatgagattg
     1021 tgcgaagaga tattcttgat agttttcttc cagataacct gtaaaaaatt cacttactgc
     1081 accagaaccg tagctgaata gaccgatgcg atctcctggc tgtagtgatt tcgaattttc
     1141 cagtagagaa gttagcccca ggtataatga accagtgtaa agattaccga ttcgtcggct
     1201 gtaacggatg ctttcttcat agcgagccat aagacgttcc tgattttctt cgtctgtttg
     1261 gtctaatacg ctttgcaatg ccttttttcc catcttagta tacggaatat ggaaagcaat
     1321 cgcctgataa tcttcgagtc ctcgacccga caattcttta tgtcgattcc aaactttttg
     1381 gaatgattcg atatacgtag aattagataa aggaccatca acaacaggaa attcgctata
     1441 atctggacgc cagaaatcat agatatcttc tgtcagaaat acgctgtcgt cttcaatcga
     1501 taaaatacgc gggttttgag tgatcatcat cgcaacagca ccgacacctt gcgtcacttc
     1561 accaccgctt gccaagccgt aacgagcaat atcacttgct atgactagta cttttcgttc
     1621 tggatgattt ttgacatatt ctttcgccat gtgcaaagct gcggtgccac cgtagcaagc
     1681 ctcttttact tcaaaagaac gagcaaaaga ttggattttc agtaaatggt ggataattac
     1741 cgcactcgct tttgaatgat caatcccgga ttctgttccg acgatgacca tgtcgattag
     1801 ctcacggtct ttttctgtta cgattttgct ggcagcattt gctcctagtg taatgatgtc
     1861 ttcatttgca cgattgactg ccatttggtc ttgaccaatc cctatatggt attttgcagg
     1921 atcatcccca cggctttctg ccaactctgt catatctaaa tataaattag gaataaaaaa
     1981 ggaaagacga tcaatcccta ttttcatttc aacacctctt tacttatgat aaaaaactta
     2041 ctttactaag gtatcataaa aagattaaaa gaaatataaa aaagagaata tttaaggatt
     2101 gttaaaattt aatcttagaa aaaaacaact ggaacaagag ctatttgttt ttacagcaaa
     2161 gaatggtata tttttgtagg aggtggctta cttgaaagaa gtcgttatga tagatgctgc
     2221 aagaacgccg ataggaaagt atcgcggaag tttaagtcca tttactgcag ttgaattagg
     2281 cacacttgtg actaaaggat tattagataa aacaaaactg aaaaaagata aaatcgatca
     2341 agtaatattc ggaaatgtcc tgcaagctgg taatggtcaa aatgttgcca gacagattgc
     2401 tttgaacagc ggtctccctg tagatgtccc agcaatgacg atcaatgaag tttgcggatc
     2461 tggtatgaaa gcagtgatct tagcacgcca gctgatccaa ttaggtgaag cagaacttgt
     2521 gatagccggc ggaacagaga gtatgtctca agcacctatg ctgaaaccgt atcagtcaga
     2581 aacaaatgaa tatggtgaac caatttccag tatggtcaac gacggattga ctgacgcatt
     2641 ttcaaatgca catatgggat taaccgcaga gaaggttgca acacaatttt ctgtgagcag
     2701 agaagaacag gatcgctatg ccttgtcgtc ccagttgaaa gcagcacatg ctgtcgaagc
     2761 cggtgtattt tctgaggaga tcatcccagt caagatttct gatgaagacg tgttatctga
     2821 ggatgaagca gttcgtggaa atagtacatt ggaaaaactg ggcacgttac gtacagtatt
     2881 ctcagaagaa ggaactgtaa cagcaggaaa tgcttcgcca ttgaatgacg gtgcctctgt
     2941 ggtgatcctt gcatccaaag aatacgcaga aaataataat ctgccttatt tagcaaccat
     3001 caaagaagta gcggaggtcg gtattgaccc aagtatcatg ggaatcgctc caatcaaagc
     3061 cattcaaaaa ttgacagata gatcaggaat gaatttatca acaatcgatc tttttgagat
     3121 caatgaagca tttgcagctt cttctatcgt agttagccaa gaactgcagt tagatgaaga
     3181 aaaggtcaat atatatggag gagcaatcgc attaggccat ccaattggtg caagcggtgc
     3241 acgtatcttg actacattag cttacggatt gcttcgtgaa cagaagagat acggtattgc
     3301 ttcattatgt attggtggag gtttaggctt ggcagtcttg ttagaagcga atatggagca
     3361 aacacataag gatgtgcaaa aaaaaaagtt ttatcagctt acgccatctg aacggcgcag
     3421 tcaattaata gaaaaaaatg tattgacaca agaaactgcg ttgatttttc aggaacaaac
     3481 actttctgaa gagctctccg atcacatgat cgaaaaccaa gtgagtgaag tggaaatccc
     3541 aatgggcatc gcgcagaatt ttcaaatcaa tggtaagaaa aaatggattc cgatggcaac
     3601 agaggaacca tctgtcattg cagctgcaag taatggtgca aaaatctgtg gaaatatctg
     3661 cgcagaaaca cctcagcggc tgatgcgagg gcaaatcgtt ctatcaggaa aatcggagta
     3721 tcaagcagtg atcaatgcag ttaatcatcg aaaagaagag ctgattcttt gtgcaaatga
     3781 aagttatcct tcaatcgtga aacgcggggg cggtgttcaa gatatctcta ctcgggaatt
     3841 catggggagt ttccatgcat acttatctat tgatttttta gtggatgtaa aagatgcaat
     3901 gggcgctaac atgatcaact cgattcttga gagtgtggca aacaagttac gggagtggtt
     3961 ccctgaagaa gagattctat tcagtatttt aagtaatttt gctacagaat cattggcttc
     4021 tgcctgttgc gaaatcccat tcgaacgctt agggagaaac aaagaaatcg gtgaacaaat
     4081 tgccaaaaaa atccaacagg caggggaata tgcgaagctt gacccttacc gtgcagcaac
     4141 gcacaacaaa gggatcatga atggtataga agctgtagtg gcagctacag gaaatgatac
     4201 acgtgcggtt agcgcttcga ttcacgccta cgcggcaaga aatggattat accaaggatt
     4261 aacagactgg cagatcaaag gggataaact agttggaaaa ctaacggtgc ctttggctgt
     4321 tgccacagta ggcggagctt ccaatatcct gccaaaagca aaagcatctt tagctatgtt
     4381 agatattgat tcagccaagg aactagcaca agtaattgct gcagtagggt tagctcaaaa
     4441 cctggctgct ttgcgtgcat tagttacaga aggaatccaa aaaggccaca tgggacttca
     4501 agctcgttca ttagcgatct caattggggc tattggtgag gaaatcgagc aagttgcgaa
     4561 aaaattacgt gaagcagaaa agatgaacca gcagacagct atacaaatat tggaaaaaat
     4621 ccgggaaaaa taaaaaagca atatctttag aagaataaag caagatttac agttatttta
     4681 tttactgcaa atcttgcttt tttctctatc agaaaatatg tttattatta gaatttttta
     4741 tagttaaggt taggcatctt aagaaatcag gcaactccaa gatatcttca ggtagaagag
     4801 aagtcgccta acattgtagg atcataggtg atttgttgga caggtcaagc tgatatttga
     4861 gcctgatgtt agaaggaatt tctttttact tgctgtagaa attattatat gactaaaaag
     4921 gctgggattt taaatcccag ccttttatga caaatagaat ttttatcgat cagtaatcgc
     4981 tgtcgctgca aattgttcga tcaaaggaat caaagtcaat ttgactttgt atttccgttc
     5041 gagtgctttt tcgataacga actcattttc agtagtcata gaaatagttg ctaatttacg
     5101 aggttcatca gcattttttt cattaataac tacttcatgt tcattttgtt ctgtgtaaaa
     5161 tttaggatac tcagcaacgg cttttgaaaa atcagcaaaa cttaaagcgg cattcgtatc
     5221 agttgagcgt gtattttcag ttgtgtccgc ttttggtttt tccgtttttt cttctggcac
     5281 actgactgtt tcttctgtaa ctggtgtcgc aacagcttgc gcagttggtt catcgttttt
     5341 caatcgttga tcattccagt aagacacgat ttcaataaga agattgtcac ggaatcgttc
     5401 gaaaatcccg ttttctcctg aacgaattct ctttaataca gtattgaagt tgtcatcgat
     5461 tggcacgttg atccgtgtat cttcatttgt tttcccagct aatccgatcg ttaagatttg
     5521 acggtttttg ggatcaagca tgacttgtaa cggcaaacca tagcgtcgca agctctcttc
     5581 ttctagagaa cggaataatt gtcctcttac accatccaat gaaggacgga attgatttaa
     5641 taatttttgt ttctgttttt tcttcatatg ttctctcctt cgctcatacc ctttcgatta
     5701 taagaaaaaa acagccaaat gaaaaggagt aatgcaaaaa aacttgcgta tacgcaaatt
     5761 acaacagaaa aatttgcgta ttttcccgtt ttttgaaaga aaaataaaaa atggaacgga
     5821 ttatgtatat atacataatc cgttccattc tttctatttt ttcggtatca aggcaaaaac
     5881 aggtagttca ggtgaataaa tgacttcatg ttcgtgccag ggtttgacca ttagcgaatg
     5941 atcgaaccgt tttttcagtt cttcgatgat ttgatcatgt gtccagtttc ttgcaggaaa
     6001 atgttggatt ttctctgcat cgatcaaaaa gacaaaatcg gaatgaaaag tctgggtaac
     6061 ttcttccgag agagaattca agcgttcgat tggatccata aaatcacctt tcgacttaaa
     6121 attgggtagt atctgggtct tttgctttgc cgactacacc atctaactga tcgatttgtt
     6181 tcatttcttc ttctgttaat tcaaaatcaa ataattcagt attttctttg attctgcttg
     6241 gtgtcactga cttaggaaga ggaaggaatt cgtgttgcag cgaccaacgc aaagcaactt
     6301 gtgcaatcgt cttgtcatgt gcttcagcga tttgtttcat ttcaggcaca tcgaagattt
     6361 taccagtgcc taatggacta tatgcttcga ggatcatatc atgttttttt gcatactcaa
     6421 ctacagttgg ctgtaattcg cctggtgcaa ggaaaacttg attgaccatc ggcataattt
     6481 ttgctgtttt tgctagtgta tctagatggt ggggtaagaa attgctcaca ccgattgctt
     6541 tgattttacc tgcttcatac agttcttcaa atgctcgcca tgtatctgca tttgcttgtt
     6601 cccaattatc acgaaaagca acagggtttg gccagtggat caaaaacaga tctaaataat
     6661 ctgtttggag cttcttcaat gattcttcaa aagaagacat cacaagttca tagctgtggt
     6721 ttgcattcca taattttgtt gtcaagaata tctcttctct aggaattcca ctttccttaa
     6781 tcgcttggcc gacactttct tcattcttgt atccttgggc agtatcgata tggcgataac
     6841 ctgcagccag cgcttcttta acagaggaaa cagcgacatc cccatcaggt gtttgccatg
     6901 tgccgaatcc tactaccggg atttcgtaac catttaatag acgataagtg cttgttaatg
     6961 aattcatact ttcagctcct tttttattcg ttcaactata agtgtagcgc atttttcgaa
     7021 aaaaagaatc cattttgttt ctactcttga aatttttgtt taaaagaaaa tgattttgat
     7081 tctggtattt ttgatttttt ttccgtaaac taagacagaa gggaatgaga aaatggatat
     7141 ctatttaaaa aaagcaattc tgcatattat tgacagagaa actggttctc cagtcttttc
     7201 acaaaaagag ctggatctga caaaagaata tattcgtgat tttcttcaaa agaagatcca
     7261 aaaaatctct tctgctcaaa caaaaactgg acaactagca gaagaaagca tgatcgttga
     7321 atcacttaaa atcgctcaag aaaattttgt ggaagcaagt gaagcaatcg ttcagcggtg
     7381 gttcgatatc taccaagaaa gtgaagaagc acctagtgca gatgtatttg ttgttttgta
     7441 tgaattagat acagtgatgt acttatcttt attgaaagtc aattatcgtg aggcttacac
     7501 tcactttgtt gaagcagacg aagcagggat cgacaaccgc ttgattttga atcgagcaat
     7561 tctaggggcg aaaacacaaa aagcagatga agcattcgct gtgaatttga ctgattggac
     7621 ctacgaatta attgaaaaaa aatatgagtt ttctggcaaa aaagagcttt atttttctgg
     7681 aagagtgatc gaaagtgttc ctgcaccttc tttagaagaa aatgtaaaag tgatccaaaa
     7741 agtagccaag catcttggaa aaaaatttga gacagaagaa tttgatatca tggctgattt
     7801 gaaagaagct gtctatgata cgatagaaga aaaaggtcgg ttggatcatg agatgattgc
     7861 ggaaaaagtc ttcaaggaaa acatcacggc aaaaatggct tttaaagaag aagtacaaga
     7921 gcaaggattt gtcccagaag cacctcctgt aaaagaagta caagaaattt ctgagaaaaa
     7981 atttggaaaa caaaaattca agctatcaaa cgggatcgaa ctgatcgtac cagtagatgt
     8041 atatcgcaac ccagatttga ttgaatttgt gaataatccg gatggtacga tatccgtgat
     8101 gatcaaaaat gtggatgaag tattgaatcg tttataaaaa tgactagaac attaggtgtt
     8161 caagtaccag tgatcagtta aatgaattgt gtcaagagaa ggatcggaaa agacgaatat
     8221 aacaaaaaaa gagcgtgaga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt
     8281 ataaacggcg gaagcagaag caactccttc ttatttcttg gagttaaacg cttctgtccc
     8341 agcctctttt tatctaataa aattttaaga ccatttacta attatcgatt ttttctgccg
     8401 catttttagg cacttcagaa gcctttattt cttcccagct taatacacct ttacgaggat
     8461 tgactttgag tttaagatac gcattcatct ttaatggatg ttctctttct tcgcgaagcg
     8521 tcacctgttt tttttcacca tctttattat aagccgcttg cttgtaggta taagtcgtga
     8581 atttctctcc gttatctgct tgggtagctg acatttcgcc attcgtcgtg atttttgtat
     8641 aataagcttc gccgccgtaa aaataatgat aagctgcaaa acttccgccg agaaatatgc
     8701 ctaaaacgac aagtacgcca attaattttt tcatgtactt cacctctttc cttattatta
     8761 acgaaataga agatttcgtc tattgaaagt tgttggcaac agctgaattt taaacttttc
     8821 ctcattttgt tcttattgct tcaaaagaaa gttaaggact atcttgaagt ttttctcaaa
     8881 aaacacattt ttttatttat aaaaggtact tttttcgcgt ataagacaag cgagtgctct
     8941 tagttgactt tgaccaatat tgacgtataa taagcttagt tcgaatctta caaaaagtaa
     9001 gtcggacgta ttctttttga tttagtcaaa aaaagactat aataaaaagg tgagagctga
     9061 aatttttcag tgatctatat tatttaggag gtttgtaaat tatggcaaaa gaacattatg
     9121 acagaagtaa accacacgtt aacattggta cgattggaca cgttgaccat gggaaaacta
     9181 ctttaactgc tgcgatcact acagtattag gcaaaaaagg cctagcaaat cctcaagact
     9241 atgctagtat tgatgcagct ccagaagaac gtgaacgtgg gattacgatc aataccgcac
     9301 acgtagaata tgaaacagaa aaacgccact acgcgcatat tgatgcacca ggacacgcgg
     9361 actatgtgaa aaacatgatt acaggggcag cacaaatgga tggtgcaatc ttagttgttt
     9421 ctgcaactga cggtccgatg cctcaaacac gtgaacacat tttattgtca cgccaagttg
     9481 gtgtaaaata cctgattgtt ttcttgaaca aagttgattt agtcgatgat gaagaattga
     9541 tcgatttggt agaaatggaa gttcgcgagt tattgagcga atatggtttc ccaggcgatg
     9601 acactcctgt gatcaaaggt tccgcattaa aagcattgca aggcgatcca gatgctgaag
     9661 ctgctattat ggaattgatg gatacagtag atgaatatat cccaacacca gaacgtgata
     9721 cagataaacc attactattg ccagtggaag acgtcttctc aattacaggt cgaggaactg
     9781 ttgcctcagg tcgtattgat cgtggtgctg ttcgtgtcgg tgatgaggta gagatcgtag
     9841 ggatcaaacc tgaaacacaa aaagcagttg taacaggtgt agaaatgttc cgtaaaacgt
     9901 tagattacgg ggaagctggg gataacgtag gcgtgttgtt acgggggatc caacgtgacg
     9961 atatcgaacg tggacaagtg cttgctaaac caggttccat tactccacat acaaaattca
    10021 aagcagaagt gtacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcaaca
    10081 actatcgtcc acaattctac ttccgcacaa ctgatgttac aggaacaatc acattgccag
    10141 aagatacaga aatggtcatg cctggtgaca acgtgacgat tgatgttgac ttgatccatc
    10201 caatcgctgt tgaaaacgga acgacattct caattcgtga aggcggacgg acagtgggtt
    10261 caggtatcgt tacagagatc gaagcataag aaacgcgact cgaatatttt ggtaatgaaa
    10321 aatgtttaaa ataaaagagc ggtccaaaca ggatttctgt ttggaccgct ctttgttctt
    10381 caattgtata agaagagatt gtagaagcat gaactttcgt tttacttcag tctcttttat
    10441 tcatcatgag agtgttcatc tatcggtatg cagtttttaa tactttcttc gtatccattt
    10501 tttcaaacca cttattctac cttgtgtctg ctcaactggc gcattatcaa taatcagcaa
    10561 agcaatcata acatatgcaa tccaactatc tctagaatat agagtataac gtgagaccca
    10621 gtttgtagcg tacttgcttt tatattctct taatccatgg aaagaataaa aatgagaacc
    10681 aaactcgtaa accaagtatg caatcctttc ctgtaaaaaa ctctttctgg aagttccgac
    10741 atttgaaaga ggggccatcc ctaaattgaa ccattggata tgttcttctt tcatataggc
    10801 aaacaaatgc aagaacaaga aatccatact gccagaaggt gcttttttag gatcatatcg
    10861 catcagatca atcgttccta ctttattgtt cgtgtaagta ggcatgatcg ttgcaaaagc
    10921 gacaatttct tcttgggtat ttttgacaac tgcaataggc gctctttgta gataatcttc
    10981 agagaaaaag cctaaagaaa accctttttc ctttcgtgaa cccaaccaat tatcagagat
    11041 atttttgaaa gtactcattt gctcagtaga aaatggtggt tgtaagacat caaatgtaaa
    11101 tccttctcgt tcgatccgat tcaagacagc acgagtgccc ttcatttttt tccctgaagt
    11161 tgtaaaacta ttcaggtcta cataagcttc ttcccccatc ttaatgaaat cgtagccgaa
    11221 ttcatgcaaa atcataacaa tctcttcgct tgtttcgtag aaaactggta aatagcatag
    11281 tcgatctgtt tcttcgataa aagcttcgat tgcttctgga aaatcttctt tcttaccaga
    11341 aggatcaccc attacaatac atttattatt gaagcaagcg aattggagaa gaacagttgg
    11401 ttcaccgtct ttttcatagg caaacatccg cttatctttt aagaagatca attgactatc
    11461 ggagtttcct ccataagttg taaggatctt cagggccttt tcttcattaa aggcttcgcc
    11521 aatctgtttc ttttctcctt gaaggaaatg aacaaataga acgatcatga aactaacagc
    11581 gatgatggcc aacaatcccg aaaaccaaat cttttcagaa ggaaataaga aaaaggaaat
    11641 aaaatggtga cgccgatgag ggaaatccgg cagattgtat accccaataa cgatgtaaag
    11701 caaggacagt gcaccaataa tgattccatc gatcgtacgc cactcccatg aatagatcaa
    11761 ttgttcccga aataattcgt ttttagaagc aagaatgatc agaagcagaa tagacaagaa
    11821 aaccaccggt gtgaaactaa aatcacttaa taaaacataa agtaaagcta gaacaatcaa
    11881 gaagattgta ggcaaatatg ctcgtttcac acgtgctgcg atccctctgc ccataatgat
    11941 taaaagaaat cccaatagta tactaggaaa ttggataata aaatgaaatt tcaatgggtt
    12001 caaactatga agccagcgaa actctgtaaa agcttgcggg atagtggcag aaagtactag
    12061 catgattcca gaaaagtata ataagacaac cacgatttta tgcgcaattt ctgttgctaa
    12121 ttgtttaggg ataccagaat aacgctgatc aaaagtggaa ccgatatttt tgaagaaaaa
    12181 gacgattcca atcaaaaacg gaatgatgta gtagaacagg cgatagagca agatccacac
    12241 aacgactatt tctcttggca caccaatagc ggacaacccg ataatcatca ttacatcgaa
    12301 actcccaatt tctcctggaa tcatagacac gattcctatc actgaagcag caatgaataa
    12361 cggaattgtt tgccacagat caatccggat ttccattaaa taaccaacag aaaggaaact
    12421 aaacaggaca ccggtccatt ccaacaatga aactagcaat agctgtcctt gagttttaag
    12481 tgaggtacca ccaaggaatc ctttcttttt gaaagtagta aataaaaaga cgacaggaaa
    12541 atatagaccg ccgccgatca accatatcca atattgcttc aaaaaaggag caactggcgt
    12601 gaagactaca agtaaaaaag aaagcagact gtaaatagaa agtccagcca tcaaaaacaa
    12661 gaaaactttc gataatgctt ggatcacgtt tctgctctct ttcttttgtc catatagttc
    12721 agagcgaagc cccacactaa caaacccgcc gaaaccggca atattgttga ttgtattgat
    12781 cagccagctt gtctcaaaca agtaacgagg attctgcttt tgttcaagca tccgattcaa
    12841 aataatatca taaccaatca taggtaacac agagacaaga ccaatcaaca gcataagtcc
    12901 gcttttccat acaggtatag tggcaaacgt ttctcctaat tgctggatag atagagtttt
    12961 accgatggac atcaattcac cgacaataat gacaatgaca gaaatcaaaa agattgtttt
    13021 gaacagtcct aggtggtttt tcagccattg tatggtattt tttaacaaat aaatcacctt
    13081 ctattcctaa tagttatgtt tcagaaagaa attgaagaac ttctcgattg aagcgttcag
    13141 gatcttttct agctaattca tgtccttgtt ctttcacaag cacaaaggaa gcttttggta
    13201 tagttttagc tatatacaaa gaatgtttta gcttgattac atcttttttt cccacgatga
    13261 tcaaagtggg ggagttgatt ttttttaaat cattttctgt aagcccgatg tcatgcagca
    13321 aaagtttgat aactaaaaga tttttgcgaa gacttgggcg aaataaagag agtaaccata
    13381 cccatgcata atgaatatta ctgatgactc tggcagaaaa acgaacgcct ttaacaagcg
    13441 tgtttccaga atttaaaatc aatcgatgaa cttttttagg gaagctgctg gcaaatacca
    13501 gtgctagatt tgctccatca ctaaatccaa gaaaatctgc ctgatcgatt ttttccagca
    13561 acatgatcgt attcagatcc tcggccatta actgaaaatt caacatagat gcttcgtttg
    13621 tcgaacgacc atgtcctcgg ctatctacta gatacacggt atagtagcgt tcgagtacag
    13681 ggacctgttc tgaaaaaaag cggccgctgc cgtcattgcc atgcagtaaa aagagaggga
    13741 agccttgacc gctcttttca tagtaaattt cgctcccatc tggcattttt gcatatttct
    13801 tttctttttt cacataatca cctactgtgt aaagtataac gattatatca gtcattgggc
    13861 aattgttttt actgaaaaac aacgatcatt ttcgtaagat gacaaaaaat acaggaaaat
    13921 tcattttttc ttaaggcgta cacagaaatc aaggaagaaa tagccaagaa gataaagaaa
    13981 tagtaagata aaaaaagatg tcaaaataac taggtgatga aatgaagcga aaacgattat
    14041 ctattatccg tattcttttt tacatgatca ttctgacggt tattggtgcg gtgttgtttt
    14101 taggaggaag aacttatcgt tcggtaaaac gagtggaaag ctatcaaata gaaataacaa
    14161 cagctgcaaa aaattatcat atggaaaact acgagaattt gatcaaggcg ataatattga
    14221 ccgaatcaaa aggaaaaggg acagatctca tgcggagctc ggaaagtctg catggagaag
    14281 ctgagatcat tgataatcca gctgacagta ttgatcaagg tgtcaaatat ttggcggaaa
    14341 tgatagtaga agcaaagaaa caaggatgcg atttatggac agctgtccaa gcatataatt
    14401 ttgggaaaga ttatattgcc tatgtaaaaa atcatggcgg agaaaacaca gtagaattag
    14461 cagaagcgta ttctaaagat gtgctgagcc cacttttagg aaatgaggaa gggaaacaat
    14521 accgatattg gcggatccag tccttgcttt acaatggcgg ctatctctat cataatggag
    14581 gtaacatgtt ttatcctgat attgtcaaaa tgaatgaaaa aataatagag acctatgaaa
    14641 aagtttttaa gtaaaatagc aggaaatgtt caatcatgaa taaaattaaa tgaaagaagg
    14701 agtgcgcaaa tagtggaaaa aaggcaaaaa atggaaaatc aaaaagtggg gtacacaacc
    14761 aaagactgga tgttacggtt tgtgaaggga atgtttatcg gttcaggatt tatcttgcca
    14821 ggagtcagcg gtggtgcatt agcagctgtc tttggcatgt atgagcggct gatttctttt
    14881 ttagcccacc ttacaaaaaa tttcaaagaa aatgttttgt tttttctgcc tgttggtcta
    14941 ggcggagtga caggcatctt tctactttct tttttagtca gttttttatt aggtgcgtat
    15001 gaaacaacga tattatggtt ttttgtcgga tgtatcgctg gaactgttcc tgcgttatgg
    15061 aaagaagcag ggaaaaaagg aagagatact tctgatgtga tcatcatggt tgttactttt
    15121 gttctggctt atttgttttt attatacggc gctcaattat ttgacgggca agtcgatcag
    15181 aattttggaa catggctgat tgccggcgga ttgattggtt tgggtatgat cgtcccagga
    15241 ttgagccctt ctaatttttt ggtgtatatg ggattgtata aagcgatggc tgacggattt
    15301 aaagaagtac gacttgaagt gattgtgccg atcggaattg gtgggattct ttgtgttctt
    15361 ggattgtcaa aaatcatgga ttacattttc tcaaaggcat atagcaagct attccatttc
    15421 attttaggtg tagtttttgc ttcaacgatt atgatcattc ctaccgatta cgcgggattg
    15481 ggagttgctg gggtactagc ttgtcctgtt ctttttatag ccggtacagc actaggttgg
    15541 tggatgagcc gtttggagga acaatataag taaagataga ttgataataa aaacagcaca
    15601 cgggtgattc aaacaaaaag gttggcatct tttttgtaaa atcattcgtg tgtttttcta
    15661 taaattttat aaaaacaagt tgtttttaat cttggaacac gctagactta aacacgtgat
    15721 tatttttgaa agttggcgga aaatggagaa aaagaaaatg aatggactta cacagcaaga
    15781 ggtagttcag aaaatggctt ctggccagca aaatgactac caggaagatg catcaaaaag
    15841 tacaaaacaa atattcagcg ataatatatt gacgttattc aattttctga actttggtat
    15901 tgggatttgt ctgttatttg taggtgcgta ttccaacatg gcgtatttag caattattgt
    15961 cgtcaatatc gttattggaa tttatcaaga aatacatgca agaaatcttg tacggaaatt
    16021 atcgattgtt tcccaatcag aagtactagt gatccgggac ggtaaagaac aatcgatttc
    16081 tactaaagag ctggtattag gagatttggt aaaaatcgga gcaggagaac agataccagc
    16141 cgatttacag gttatatctg gacgggcaga agcaaatgaa gctcttttga caggcgaatc
    16201 tgatttgatt gtcaaagaaa ctggagctga attgctttct ggaagctttt tgacaagcgg
    16261 ttctgtcatg gctgaagtta tccgagtagg tgcagataat tatgctgtcc gcttgactag
    16321 cgaggcaaag actcacaaag ctattcgttc tgaacttgta gattcgattc gcaaagtatc
    16381 caaattcact agtttcgtga ttattccttt ggggatcata ctatttttgg aagcactgtt
    16441 catccgcgat gcttctatca aaatttctgt tattgcatct gcagcagctt tgttaggcat
    16501 gcttccaaag ggtttggtat tgctaataag tattgcatta acgacagggg taaccaaact
    16561 ggcaaaaaaa cgaatccttg ttcaagacat gtattcaatt gaaacgctgg cccatgtcga
    16621 tacattatgc ttggataaaa cagggaccat tactgaagga aaaatgagta tccagcgggt
    16681 agaagcacta catccgctgt acgagaaagc catcccagaa attatgggga cgtatctggc
    16741 agaaagcagt gataacaaca tcactatgcg ggctatgaga gattattttg agctttctaa
    16801 tcggtatgat gtgacaaaca aagtcgcatt ttcttctgat cgcaaatggg gcgcgatgga
    16861 atttccagaa ctgggagtcg tgtacgtagg agcgcctgaa cgtttggtgg aagaagatcg
    16921 gcttccggac agtctaaaaa cagcccaagc gaatggctat cgcgtactta tgttagggat
    16981 cgctccaaat cagcaattga acgaagaaaa accagcattt gttgagccgg ttgctctgtt
    17041 tgaaatcgat gatccaatcc gaaaaaacgc tcaagaaaca ctagcttatc ttcatgagga
    17101 aggtgtggat ctgaaagtga tttctggaga caatcctttt actgtctcca atatcgctag
    17161 acgtgcagga ttaccgaatt atgatgcgta tgtcgatctt tctcaaatta ctgaagaaat
    17221 ggaagtgcga gaagctgctc atcgctatac ggtttttgga cgagtgagtc ctcagcaaaa
    17281 gaaattgctg gtaaatgaat tgaaagaaag cggcagaacg gttgcaatga caggcgacgg
    17341 tgtgaatgat gttttggcgt taagagaagc agattgtagc attgctatgg cagaaggtga
    17401 tggagcaaca cgtcagattg cgaatctggt attgttggac tctgatttta ctacattgcc
    17461 agaagtcctg tttgaaggac gccgagtggt caacaatgtg acgaaagtct caggcatctt
    17521 ttttatcaaa acgatttatt catttatttt atcgattata tgtgccgtta cagcaattgg
    17581 atttccgttt atccctatcc aaatcacgct gattgattta gcgattgaag ggtatccttc
    17641 cttcttttta tcttttgaac aagataaaag aaaaatcact taccgttatt tgcctacagc
    17701 acttattaat gctttaccaa atgccttgct tgtagtagtg aatatcattg cggtgtatct
    17761 acttggaaaa acattcgcat ggggaaatgc tgaaactact actttgatgt attacttgct
    17821 gattgggatc agttgcatgg cagttgtaaa agcttgttat cccttcaacc cattgcgcat
    17881 cttcctagca gtaacgacga tcgtagggat atatgtagct gcaatgctgt tccatggaat
    17941 tttggaagta aacttagggt tgggagagag cgtaggatac ttctttgtat tcatgctcgt
    18001 aaatattgtt cttcgagtat tgtactggaa ggctgatatt caaaatcagt tactgaaaag
    18061 agtagcaaat tgatgcttaa tgagatagaa atgtgttata cttgaaaaag caatgaaata
    18121 tgatacaatc aaacatgtat aattgtgtcc tttaaaatcg cactgatttc agttagtgcg
    18181 attttttacc ggttattctc ctgaaatatc ttctgttaaa cccaaaagat atcaatagag
    18241 cagggggtgg aaaaatggct caacggattc ctcaagaggt tatcgaaaca gtacgcagtc
    18301 aaacgaatat cgttgaggtg attggacaat atgtccagtt gaaaaagtct ggtaaaaatt
    18361 acttggggct gtgtcctttt catgaagaac gtacaccgtc tttttctgtt gcagaagaca
    18421 agcagatttt tcattgcttt ggttgtggta agggcggaaa cgtgtttact tttcttcaag
    18481 aactagaagg tctaagtttt ccagaagcag tggtaaaagt ggcagacttc gaacagatac
    18541 cgttagaaga tcaatggcgt cagcgtacta tagctgtcca aaatcctgaa tctgctacgg
    18601 ggaaactgat tgctgctcat gaaaaagcag cggaaatcta tcatcacatg ctattgcata
    18661 caaaagctgg acagccagct ttagaatatt tgcaaagtcg tgggttgtct ttagaattaa
    18721 ttgaagaatt caacataggt tttgcaccta atgagcgttc ttttcttcag caagtattca
    18781 agaatgaatc aatttcaaat gaattgttag aacgctctgg attgtttgtc acgcatgatg
    18841 atggccgtat gtctgatcgt ttttatcaaa gagtgatgtt tccacttcgt aattctcaag
    18901 gccagacgat cggtttttca ggacgctggc ttgcacctga aaaagggcag gaaaaagatc
    18961 agcccaaata cttgaatagt ccagaaacag aactgttcaa taaaagacaa gttttattta
    19021 atcttgataa agcaagaagc gatatccgga aaaacggaga aattttgttg ttcgaagggt
    19081 ttatggatgt gattgctgca tggcaggctg gtatcaaaac tggattagct tctatgggga
    19141 caagtctaac agctcaacag atccaacaaa tggaaaagct gacgaaagaa ttggtctttt
    19201 gctatgacgg agacaacgca ggttttgaag caaccaatcg agggattgaa ttgcttcggc
    19261 aaaacagtcg cttagcactt tctgtcgtag tcgttccaga aaagcttgat cctgatgaat
    19321 atctccgtaa gtatggagaa gcatctttcc aagaattagt ggctcatggg cgcgaaacag
    19381 tctttacttt taaatcacgt tatttaaaac aagggaaaaa tttagataat gaaaaagaca
    19441 agatcgaata cctcgaagaa ttactagttg aacttagccg agttgtttca ccaatcgaac
    19501 aagatatgta tctatctcaa ctgtcaacag agtttcagat cggcagagag acgatacaaa
    19561 aacaactgcg cgatcttcga aggacaaatc agcaaaatcg tcaagaacct caggaaagtc
    19621 aacacactca ggttacgaga caagaaactg cacggaaaaa gagacctttg acgcaagtag
    19681 aaaaggcaga gcagattcta ttatatcgtg catttaaaga agtttctgtc cgtaatattt
    19741 taaaagaacg agaatttcag tttattcatg atgcatatgc agaagtttat tttttattcg
    19801 atgcatatgt ctcacaacat tatgaattca accttgcaga gtttttagac tttttgcaag
    19861 atgaaaattt aaggcggttg gtggtggaaa tcgaatattt accggtggca gaagaaagtt
    19921 cgccacgaga aatccaagac ttgctagatg tgatcagcaa atctggctta gctgatgaaa
    19981 taacattaaa aaaacaaatg cagcaagaag ccagacgaac tggaaacaaa cagcttgagc
    20041 ttgaattgac gattgaaatc atcaatttaa cgaaacagtt aaaacaagcc aaatagctac
    20101 tcaagggggg ccttctttta tggcaaatgg aacagataaa aaaacgtatg aagcagcagt
    20161 agcagctttc atcaaagaaa acaaacccaa acgacaagtt gtatatgatg atttatccaa
    20221 tcagcttgct acaccattca ctttgaatgc agatgaaatg gacaaattga tccaaaagat
    20281 tgaagacgca ggtatcagtg tggtggatga aaatggtgat ccatcaattc acagcttgaa
    20341 gagtgctgag aaaaaagctg aacaagcaaa aacagaagat ctatctgcgc caaccggtgt
    20401 aaaaatcaat gacccggttc gtatgtatct gaaagaaatt ggccgtgtct cccttttaac
    20461 tgcggaagaa gaagtagcgt tagcattgaa aatcgaagaa ggcgaccaag aagcgaaaca
    20521 gcgtctggca gaagcaaacc ttcgtttagt agtaagtatc gctaaacgtt atgtaggacg
    20581 aggcatgcag ttccttgact tgatccaaga aggaaacatg ggactgatga aggcagttga
    20641 aaaatttgac taccgcaaag gatttaagtt ttcaacctat gctacatggt ggattcgtca
    20701 agccatcact cgagcaatcg ctgaccaagc acgtacgatc cgtattccag ttcatatggt
    20761 tgaaacaatt aataaattga tacgtatcca acgtcaattg ctgcaagacc ttggaagaga
    20821 acctacgcca gaagaaatcg gtgcggaaat ggatcttcca acagaaaaag tccgagaaat
    20881 cttgaaaatc gcgcaagaac ctgtttcact tgaaacgcca atcggtgaag aagatgactc
    20941 tcacttaggt gatttcatag aagatcagga agcaacaagt ccagcagaac acgcagctta
    21001 tgagttacta aaagaacaat tggaagatgt actagataca ttgactgacc gggaggaaaa
    21061 tgtccttcgc ttacgttttg gtttagatga tggccggacg agaacattgg aagaagtagg
    21121 gaaagtattt ggtgttactc gggaacgtat tcgtcagatc gaggctaaag cattaagaaa
    21181 attgcgccat ccttctcgtt caaaacaatt aaaagatttc ttagaataag catgaactat
    21241 tgaccagaag agaaatcagt aaaactgttt ggtttatttt aaaagaaaaa aagcttgaga
    21301 ctacgcagtc tcaagctttt ttttctatag gaaggaaatt cattcattat ttttaagtaa
    21361 atcctaaaaa taagctattg gcgtgacgta tagaatatga tagattaaat ggtagcgtaa
    21421 acctagtaaa ggagccgatc gctaagtgat gaaaaaatgt ccaaattgcg gatcgaaaaa
    21481 aatggagcag aatactatct gtccagactg cggtcatcaa ataactgcag aagatcagca
    21541 aataaaagaa tcaattgaag aaacaaatac agatgcagct atgcaggata aatcaactga
    21601 agatgcagtc tttcctgata cagaattaaa cgatccaatc gaatggtcgg aattgaaaga
    21661 tttacctcta gaatctgtaa tggaattatt cgaaaaagca gaaccagaag acgaagaacc
    21721 acctgctcac gatcaagtaa ctaatataga gaaaaatgaa cagaagaaag caactgttca
    21781 tgagacttcg gaagaatcag gaaagaatca agaagaaacg cttgaatcaa aacaaaaaag
    21841 aagagtagct gaactgaaag aaatcgtcga taatgaggaa gaaaattcga tactatccgc
    21901 ttatatcaaa gcacatcgtg aagatacaaa agaagagcac gcgaaagagc tgctcaaaat
    21961 gatcagtgaa aaaattgcac aggaaaacaa agtagagcca gaacatgaag ctgaaaaaga
    22021 cactgaaaaa gacattagtg gagtaaacgc tgcaggtaaa gaatcattaa aaacgaatga
    22081 tctaaaaacg aatgatctaa aaacggatat cccggaaaaa actgaaacat tgtctgaaaa
    22141 acaatcagaa gacgagaaat cgaatgggtt gccggaagca gataaaaaag aaatgctcga
    22201 aaaagcagac aagaaggcaa cagagtcgga tggaataaat aatgaagccg atgctgaaac
    22261 tcaatctgca agtgaagata gcactgctct tgaagctaaa atagaaaaag aagagaacca
    22321 gcctgagctg attgaagcag aaacagaacc aataacaatc gtgccaaata ctgaaaaaac
    22381 gcctcaagaa tcaaacccag aaaaaaaaga tttagataag acacaaaaga aaaaatcaaa
    22441 aaaagtgccg tatctcgctt tagcagcagt tcttctacta ggtgggggag gctgggctta
    22501 ttatgaccat catcaaaaag tagaagccga agtagcagca gaagcaaaaa gacagcaaca
    22561 aatggaagaa cttcatgaga aacttgctgc cttttataca gatgatcacc atcaatttat
    22621 tcgtgcagat atgattcatc aagatttatc aaaactaaaa aatgatttat ccagtcttaa
    22681 gaatgaaaaa ggatattcag agttagaaac aacttaccaa gatatccaat ctaagatccg
    22741 agatatccaa aaagtgaatg agtggttcat agcacctgcc atcgtcgatg atcatctagc
    22801 agatgacatc aagttgaaag cagataaaga gatccaagca atcgaaacgg ataacacaga
    22861 ttttggaaaa ttgattcaac aagcacaaac agaagctaaa aatcaatatg ctgaattgca
    22921 aacagctaaa gaaaaaacag ctatagtctt taaagacgga aaagtagtgg attcagcaac
    22981 acgcgaccaa tacaagacgg caaaagaagc agtagaaaaa gtgaaaaata cagatctatc
    23041 tgctcagttg aatgaacaat tgcaacaagt agataagatg ctcactgata aagagaaaaa
    23101 agaagaagag gaaaagaaaa aagcagaaga agcgaaaaaa gcagaaaaag cgaaaaaagc
    23161 agctgaagaa caagcaaaac aagccgctca agcagcagct gcagctcaag ccgctcaaca
    23221 agctgcggtc gcacaagcag cacagcaaga agcggcatcc tcgacccctt cctcttcaaa
    23281 ctcagcgaat cagccaatca aatctgccag agcaagtgat attgccgatg catctaatcc
    23341 agcatggacg tgggcaccag gtgtccaaag caaagtgatt gctacatgta tccaacgtgg
    23401 atatatcgtt gaaggaggat acagattaga aaaagccaga atcgaaaatg gggaaggcta
    23461 ttacaatcta tatgccactt caacaaaatc tgcattgatg aaaggcattg gagaaagtgc
    23521 tttgccattt tacatcgtaa ccatcaactg taaaactgga tggttcggag gaaatgggag
    23581 caattaattt taggcaaatg aaagaggctg tgagcctgcc gtttaacacc gtttattcga
    23641 aaaaggggag tatgacacaa ctgttgtcat actccttttt tcacctttcc aaaccaaggc
    23701 tcagctattc aagtagataa cattatgtta tgatagcaaa gaaatgtatt aagaaaacct
    23761 ttcactatag agggagaaaa aaatgaacga tttattagca actatattta caggtattat
    23821 tattgatgaa aatgaaaaaa actactttgt ccaaaaaaac ggacaaacct ttggcttaag
    23881 caaatcagaa ggtgaacaca aaatcggtga agcagtggaa ggattcggct accaaaatca
    23941 aaaacatgaa aatcggatca ctacacaaat tcctaaaagc cgtatcggtc attacgcttt
    24001 tggaatcgtt actgctacac gaaaagattt aggtgcgttt gtcgatatcg gtcttccaga
    24061 taaagacttt gtcgtatctc ttgatgaatt gccgacaatg acagagctat ggcctaaaaa
    24121 aggggatcgc ttgatgattt cccttagagt tgatgcaaaa gaccgtattt ggggcagttt
    24181 agcagatgaa aaaatattca aatctttaag caaatatgga acagaagaaa tgaaaaacaa
    24241 agatgtgata ggaacagcat accgcttgaa attaacaggt acgtacgttt taacggaaga
    24301 tttctatctt gggtttatcc atccttctga acgatataat gaacctcgtc taggcgagca
    24361 aataaaaggt cgagtgattg gtgtccgacc agacggtgta ctgaatcttt cattgaagcc
    24421 aagagcatat gaagctatat cagatgatgc acaaatgatt ttaaccattt tagaacgttc
    24481 tgcagatcag caaatcaact ttacagataa atcggatcca gaagaaatca tgaaagcttt
    24541 tggtatcagc aaaggagcat ttaagcgcgc attaggtaat cttttgaaac aaggattgat
    24601 tacacaagaa aacggtgtga caaaactagt caaaaaatct aattgagaat cccttgcatg
    24661 tttttcttaa ctagcttata ataattttaa ttaacatagt gttatatctt tttttatttg
    24721 taattattat aaattgttgg ggttgagtaa atggtcatga atgctatttc ggcgatgaaa
    24781 aaaacaaaac agcagctaca tgaagcgggg tttaagctga caccgcaaag agaagctact
    24841 ctgcttgtgc ttttggaaaa tgagaaagag catttatctg cagaagaaat cttcttttta
    24901 gtgaaaaaaa agagtccgga aattggactt gctactgttt atcgaaccct tgaaatcttg
    24961 acagaattga aaattgtcga taaagtaagt tttaatgatg gattagcccg ttatgatttg
    25021 agaaaagaag gcgccaaaca tttccatcat catttactat gcttgaactg cggcacgatc
    25081 gaggaagtag aagaggatct tttacttgaa gtggagcaag tagtagaaga acgttatcat
    25141 tttttagtaa aagatcatcg gctaacgttc catggaatct gtcaggaatg ctatgaaaaa
    25201 gaaaaaagaa accagtccgt ctgagtgtct agacggcttt ttctttgctc agattatgga
    25261 aaaagactat cagaatgaag cggtatctga tatgatagag aggcatgagg gggattatta
    25321 tgaaagagca aatcaacgat tatctccact acttgaatat tgaacgggga ttgtccgcca
    25381 atacacgaca aagctatgaa cgtgatttgg aacagtactt gcattttcta caggagcaga
    25441 aaattgcttc atggcaggat gtcgatcgct ttttagtcat ccgttttctg gagaagttgc
    25501 atgaagaaaa aaaagcgaca gcaactgtta ctcggatgat ctcaagtctc agaagattcc
    25561 atcagttttt acggcaagag cgtatcactg atcatgatcc gatgcaacat atcgatacgc
    25621 cgaagaaagc acagaaatta ccaagtacat tgactctgac agaagtagaa aagctgattg
    25681 aagcacctga tacgacaaaa acgttaggga taagagatcg tgcaatcttg gaagtcatgt
    25741 atgctacagg gatgcgcgtc agtgaattga ttggattgaa attgggagat cttcatcttt
    25801 ctcttggact ggtacagaca gttggaaaag gagataaaga gcggatcatt cctttaggtg
    25861 attatgcgat ccaatggctg gaacgctact tagacgaagc acgtccatta cttgtaaagg
    25921 acgcatctga aatgcatgta tttgtcaata atcatgggaa aggtctttct cggcaaggaa
    25981 tctggaaaaa tctgaagcag ctagtacgag aggctgggat ttacaaagaa gtaacaccac
    26041 atacgctgcg gcatagcttt gccacacatc tgctagaaaa tggagctgat ttgcggacag
    26101 tacaggaatt gttaggtcac gcggatatct ctacgactca gatttataca catatcacga
    26161 agaaaagaat gacggatgtt tataagcagc attttccaag ggcttagtca taggaaggtg
    26221 agaagatgtt aacacattac cggaaagaaa accgtaaaat tgctatggga ctattgagtt
    26281 tccataagaa actgacaggt aaaacttctt tgttgaagga gattgatacg tacgaatctg
    26341 aagacgatta tgaacttttt ttctttacgc cagaaggttc aaccaacatt caagggatta
    26401 ttggtgttta ctgggcaacg aacgatcagc tgatcatcca tgacatttct ttgaatccgt
    26461 cttatcgcgg tgagaatatg ggctttcaaa tgttagatga attacaggaa aagtacccgg
    26521 atgtctccat ccgtgcaact gaaatcacag agccttacat tggaaaatgg ctagcaaaga
    26581 aaaagaagaa agagtgaatg agttgacgga gatcaatatt aaattagatg tattcgaagg
    26641 tcctctcgat ctgctgcttc atctgattca gcaaatggaa atcgatatat atgatatacc
    26701 gatcgctacg atcacggagc aatatatgaa ttatatccat acaatgaaaa cactagagct
    26761 agctgttgca ggagaatact tagtgatggc tgctacattg atggcaatca aaagcaagac
    26821 attgcttcct gtccaagaat tcgtcacaga tgatgaagaa ttatgggaag aagatcctcg
    26881 agaagaattg gtcactcagc ttttagaata ccgtaaatat aaatatgcag ctgaaagact
    26941 gacagaaaaa gcagaggaac gaagtcttta ttacacaaaa gaacctatga acatcgatgg
    27001 gttagcggat gctgaaaagc cgttgaagcg aggacaagtc aaaaaaatcg atttgatccg
    27061 tgccatgcag aaaatcttag aacgtaagaa attttctcaa aaagtggaaa aaacgatcac
    27121 gcccgatgac acaacgatcg aagaacgaat ggtatttatc gaagagcgta taaaaagaaa
    27181 tgcgcatggc tgtactttcg attctttttt tgagtcacct tctaaaagtg aagttgtcac
    27241 tacttttatg gctttgctag aattgatgaa aaaagggcag atcattgcgc aacaaaaaga
    27301 aaactatgaa tcaattatgc tttatccagc agtaggagat accgaacatg acgaaattaa
    27361 gtgaacttga agcccttctt tttattgttg gcgaggaagg gatcagtaat gaagaattaa
    27421 gcggactgtt aaatctcagc gaagcagaag tcacaagttt agtgaaagaa ttaaaagaat
    27481 cttacactca aaactcgcac tcagctttgc atatttttga aacggaaagc cattatgtat
    27541 taacgactaa aaaagagctg gctcccttac ttaagcgata tgcgcaaggg acatcaaaca
    27601 cattatctca agccgctgtc gaaaccttag caatcatcgc ttataaacag ccaatcacaa
    27661 gagctgaaat cgagcagatt cgaggagttc aggtttcagg agcggtacag cgtctagctg
    27721 cccataaact gattgaagaa aaaggtagag tagaagggcc aggtcggccg atattatatg
    27781 gaacaactgg ctacttctta gattattttg gtttgaaatc attagaagaa ctgcctgata
    27841 cacaagaaat ggaaatttca tttgaagaag acgtgtcacc agatctattc tttgatggaa
    27901 tgaataaagg agaataattg taatggaaag attgcagaaa gtaattgccc acgctggcat
    27961 cacttctcgt cgaaaagcag aagaattcat ccttgcagga cgtgtaaaag taaacggaca
    28021 agttgtaagg gaattaggga taaaagttgg gaaacatgac actgtggaag tggatgaagt
    28081 cccaatttat caagaagaat acggttatta tttattgtac aaacctaaag gagttatttc
    28141 tgctgttgca gatgacaaag gaagaaaagt tgttacggat cttttgccga tggtaaaaga
    28201 acgtatctat cctgtaggtc gactggatta cgatacttcg gggatcttgc tactgacaaa
    28261 tgatggagat tttgctcagc gcctgacaca tccaaaacat gaagtggata aagtttacgt
    28321 tgcaaaggta aaagggatcg ctacaaaatc gatgcttgca cctttgacaa aaggaataaa
    28381 gatcgaagga cgaaaaacat ctccagctaa attccaaatt ttatcagtgg atcctaagac
    28441 aaaccacagt atcgtggaat tgacgatcca cgaaggacgt aatcatcaag tgaaaaatat
    28501 gcttcaagca gttggtcttc ctgtgcaaaa actaaaacgt gaaaaatacg gagatctgac
    28561 tttacaaggc ctacgtcctg gagattaccg tgaactgaac aaaaaagaag tcagcagttt
    28621 gctgaaccac tcaaaatgaa cacttacttt ttataagtgt tagatgttgc gttttttgaa
    28681 tagatatgta taatgaatat gtaaacaaaa attatataag gttcgtcttc aggggcaggg
    28741 tgaaattccc gaccggtggt tatagtccac gacctatttt gcaaaaaata gctgaatcgg
    28801 tgaaattccg ataccgacag tatagtctgg ataaagaaga tagagcttat ttgacgacgc
    28861 ttgatcaaat aactctaact ctattttccc tggaaaatag agttttttca tttggagaga
    28921 aacgtcaaaa agttcgctga agaggagtcc taacaggagg atttcaaatg aagaacaccc
    28981 gtgtacagaa aatggttgca gtagcgatgt ttgctgcgat cgcgttagtt ttacagtatt
    29041 ttgcttttcc gatcatgccg gcttttagtt ttttgaagat cgattttagt gatatcccgg
    29101 tattgatcag catgttctta ttcggtccag cggccggagt tgcaacagcg ttcttgcgtt
    29161 cagtattaca tctgctgact acaggttttt ctccggataa tttggtagga gacactgcta
    29221 gtttcttatc aacaacgatc tttacattcc cgatttatta tttctttagt gtaaagaaac
    29281 agcataaagg aagaaacaaa tttttaggtg tcattacagg aaccatcgct ctaactattt
    29341 ttatgagtat cgcaaattat ttcgttatta cgcctcttta cttaatgttt ttaggactga
    29401 acgcaacaca gatgctaggc atgtctttag caaactatgt actgattggg atcgttcctt
    29461 tcaacttgat caaaggattc atcgtgagcg ctgtcttttt agtgctgcat gcgcaacttc
    29521 ttccatggtt aagtcgaaaa caacatcagt tcgaacaacg tcatacagca gtcaaataat
    29581 tatcaaaaag atcaagaaat ttcttggtct ttttttttgg aaaaaaatac aagacatgca
    29641 ataatgtaaa cgttttattt gtttgttttg agtatttttt tgatttatgc ataaaaatca
    29701 atcaattctt tgcaaatgtg aaattcttct ccttttaaaa gacgaaaatg tttgtttata
    29761 aaaaaaagga aacgctacaa tgaaaaagaa gaaagcttta aaaacctgaa aaaagaggag
    29821 ggaataggga aaaacgaact ttttgaacaa aagttttaca aaatgcgtgt tattattttt
    29881 gttctgatac tctttttgat aaaataacat tagagccaaa attgttgtct ctaacggaaa
    29941 agaaaggaag aagaagatgg aacaaacaaa aaagaaaaaa tttcaaatgc cttcagcgta
    30001 tacggtctta tttattatta ttgcagtaat cgctgtactt acttggttta taccagctgg
    30061 gcactatagt gtagacgatg caggcaacat cgtcgctgga tcatatgaac gagtacaaca
    30121 aaatcctcaa gggctgtggg atattttcat ggcgccaatc aatgggatgt taggtgtacc
    30181 agcgggggag ctaactaaag aaacacctgc tgcaatccca atctctttct tcattttggt
    30241 tgttggtgga tttttaggta ttatcaacaa aacaggggca ctagatgccg ggattgcttc
    30301 agttgtgaag aaattcaaag gaaaagaaaa aatgcttatt ccagtattga tgctgttatt
    30361 tgcattaggc ggctctactt acggaatggc agaagaaacg attccattct atgctttact
    30421 gatcccagtt atgatggctg taggctttga tacagtagta gcagtagcaa tcgtattagt
    30481 agggtctcaa gtaggctgtc tagcttcaac ggtaaatcct tttgcaacag gcgtagcttc
    30541 acaagctgtt gggatttcga tgggtgaagg tattggtctt cgattcttga tgttcgttat
    30601 tttgttagct atttctattg tatatgtgta tcgttatgca tcaaagatcg aaaaagatcc
    30661 aacaaaatca ttagtataca accaacgtaa agaagatatg aagcatttcg atattgaagc
    30721 aatcggtcgt caagaagtaa tcacgaaaaa acaaaaacat gttaatgtat tgttctttat
    30781 tacttttggt atcatgatca tcagtttgat tccttggaca accttgaatg cgaatttcac
    30841 gatttttgaa tcattgacaa actggttaac aaaccttccg gtactaggta ctgttctagg
    30901 taaaagcatg cttccattag gtgactggta cttcccagaa attactatgt tattcttagt
    30961 aatgtccatc gtagtagcaa tcacttatgg catgaaagag tctgaatttg tctctgaatt
    31021 tttagctggt gcttctgatt tgatcggtgt agcaatcgta gtagctgttg ctcgtggtat
    31081 ccaagtggtt atgaacaatg gattaatcac agacaccatc ttacattggg gcgaacaagg
    31141 attaagttca ttatcttcaa gtgtattcat cattattaca tttattttct atatccctat
    31201 gtcattcttg attccttcaa cttccggctt agctgctgca acaatgggaa tcatgggacc
    31261 tatgggtgaa tttgccggcg tcggtaagga tttagtaatc actgcttatc aatctgcatc
    31321 tggtttagta aacttaatta caccaacatc tgctatcgta atgggtgctg tagcaattgc
    31381 tcgtttcgat gtttcagtgt ggtggaaatt taccggtaaa ttaattgcga tattatttgt
    31441 agccatctgt gtgatcctag gtgtagcagc aatgttctaa acctagacaa atacaggtac
    31501 aaggtctatc ataagaatga agaaaccgat aaacggctat cgataagcac gtggacaagt
    31561 caatagctcc attcagtgag tgttttttct ttcatcattt gttaagaaca ttctgcttgc
    31621 tgatggagca ggcttaaaac gtcattattt gagaagaaga ggttgtgtcg gaggaatttg
    31681 acatgaccct ttttaacata ttaggaggat aatatcatga aaaaatttgt gacagaacaa
    31741 catcatgaac aagcattaga atcattgagc gaattgatcc gaattccttc cgtactagat
    31801 gaagcagatt caggacaagg acatcccttc ggtaaaaaag tgattgaagc tttggataaa
    31861 gtattggaaa tcagtgaaaa gctaggattt agaacattta aagatccaga aggctattac
    31921 ggttattcag agattggctc tggagatgaa ttattcggta tcttgtgtca tatggacgtt
    31981 gttccagcag gggacgaaaa taattgggaa acaaaaccat tcgatccaac tataaaagac
    32041 ggctggttag ttggtcgcgg atcccaagat gacaaaggtc cttctattgc ggcaatgtat
    32101 gccgtcaaag ctttgattga tgctggcgtg gaattcaaga cacgtattcg ttttatcttt
    32161 ggtacagatg aagaaaattt atggcgttgt ttagaaaaat ataacgaaaa agaagaagga
    32221 attacgcaag gatttgcgcc agatgctgaa tttcctttaa tttatgcaga aaaaggctta
    32281 ttgcaagctt acttgacagg accaggaacg aacgagtttt ctgtaaaagc tggaggagcg
    32341 ttgaatgttg ttcctgatgc agctccttac tctggagaaa agctttctga agtaaaagaa
    32401 gcgttgaaaa aacacgaatt cgatttcgaa gaacaaggtg aaggcatcgt cgttcttggt
    32461 aaaagtatcc acgcgaaaga tgcagcacaa ggagtgaatg ctatttctcg tctggcaatt
    32521 gctctttcag aagtattcga ttttggccca atcaatttct taggaaaatt agttcaagaa
    32581 aatgcaactg gtgaagctgt cgtgggcaaa acagaagatg aacaatccgg cgagctaacg
    32641 atgaactttg caagtttgga aatcacacca gaacaaacaa aaatcggtgt agatatgaga
    32701 atccctgtta cattcaagaa agatgattta gtagctaaat taactaaaac agcagaaaaa
    32761 tatgggttga cttatgaaga atttgacttc cttgattcat tatacgtgcc actagacagt
    32821 gagttagtga aaaatctatt ggggacatat cgcgatatta ctggagacat gactgaaccg
    32881 tttgtatcag gcggcgctac ttttgctcgt acgatgaacc agtgtgtggc attcggtgcg
    32941 atgttccctg atactcctga ctttatgcac caggcgaatg aacgatggga attaagtagt
    33001 atgtataaag caatggaaat ttatgcagaa gctgtgtatc gtttatgtgc taaataaaaa
    33061 taaacataca aaaagggcgg atattcaaat ggatattccg tcttttttta tttgatgctg
    33121 gaaagtttgc atttctctct tatttttttt aaggtataat catacttgat taagaaaaag
    33181 gggtcactca gatagaaaag gtgggagaaa gtgaaaatat ttagacgaat actaattggc
    33241 ttagtcatca ttttaggatt actcggtgga gccggttatt actatataca gcaaaatacg
    33301 tacgaaccat cgtcagaagc gcaagtgttg gtaaaagaag gaaaaaacaa agaagattac
    33361 ttattttttg aaggagagaa aaagaatcat ggaaattctc cattacttat tttttatcct
    33421 ggtgctctcg tagagccaga aagttatagt atttgggcgc aagatttagc aaaaaacggc
    33481 ttttcagtcg ctattgtcaa aatgccactt gatctagcag tgatgggcgg aaacaaagcg
    33541 gataaggtca aagaagattt tccaaattcc gattatgtga tcggtggcca ttcattaggt
    33601 ggcgtaatgg caagtcgtta tgtcaataag aatcattcag acaaacattt aaaaggggta
    33661 ttcttcatgg caagttatcc cgacaaaaaa ggaacattga cagaatcagc tgttcctgtt
    33721 ttatcgatca cggcgacaaa agataaagta ttgaatcagg aagcttatca agaagctaag
    33781 cagtatttac cggaaagaac agagtatgta tcaatcaatg gcggaaatca tggaggtttt
    33841 ggcagctatg gtgagcaaaa aggagatgga gaggcagaaa tttctaacgc agaccagcaa
    33901 actgtgatcg tcaatacatt ggaaaactgg ctgaaaaagt tgaaataata taaatgggtc
    33961 ctatagggtc cgtgaaaaaa ctagtcaatt aactatagat agcaaatgaa tctttcaaaa
    34021 taagtcggga tttcacggaa caagagaaac agatcccggc ttattttcaa gtttagagaa
    34081 cttagtgtac gtttttaaag tttcgtttat atttatattt tattttctaa taaaatcgct
    34141 cgaactggac atttttgata cgcttttttt acatatgttt cttcttccgg catcacgaac
    34201 tgttgatgag cctctggttc ttgggcaaat aaaacgattc cttcttcatc ataatcgaaa
    34261 atatctggcg cttcgatttg acaaagaccg catgcaatac agcgttcagg tacaagttta
    34321 catagtagtg acatttctaa ccatcctaac ttaaggagaa taatatgatt gtttttattt
    34381 tatcgctatt ttcatcagga cacaagctgc ggattagttc tctttaccaa ctccttgtgg
    34441 gaaaacgaac gacttcagta cttatttatg gatttaccca cgaacttttg tttatccata
    34501 acagttttcc agaattgaag caggataagt tttatcaaat tttgcaaaaa attgcgcagc
    34561 aaggttggat cgaaataaat gaaaatgaag caaagctaac gcctgcaggg gctgatatgt
    34621 tgtccgaaca tcaaatagaa catactggtt tgcgttttga ccgctatggc agaacagggg
    34681 aaactagttg gcggctcatt aaatttgctg ttcaagtaat ttctaatctg gcaacgggta
    34741 ttcaagacta tcttccagca gagacaagtc ctttttatac tttccaacta aaaaaatggc
    34801 ttagtgaaag ccaattgcca cgtgaaattt tgattgatac tgcgtatgag agtttggtgc
    34861 agctgttttc ggagatacca gaagaagcag cagatttttt agctaaccaa ttatctggaa
    34921 atgagcgaac agggctgctt ccttatcagc tggcaaaaaa caatgatgag tcagcggttt
    34981 atctgcaaca aagcagatgt atccaccttt tgttagcaca aatcgaaaaa cggccagatt
    35041 cgctttggca cgctttgatc gattcattat tacagcaaaa tttcaatcaa agcatgatga
    35101 tcaccaagca gatgtttatg aatggtcaga caattgacca gattatggca atccgtcatt
    35161 taaaaagagg aacagtaaca gatcatctta ttgagtgggc cttgtttttt gatgattttc
    35221 catacgagcg gattctctct gcagaaacaa tcgaacgttt ggaaccaaat aaggattccg
    35281 tgcgagagtg gcgctttagc gaatggaatg tagatggaca attagattat ggagaatttc
    35341 gtttgtatca aatctatcta ttgagaaagg aagcgataca gaatgttaat aaatgaatta
    35401 aaaaaatatt ttggatttga ttcatttcgt cccggccaag aagaaatcat tcaggcgttg
    35461 cttgatggag aagatactct cgctattttg cctacaggaa cgggaaaaag cctttgctat
    35521 caattgacgg ggtttttaat ggaaggtctg gtcatcatcg tgtcaccgct gctttctcta
    35581 atggaagatc aagtgacgca attacaaaaa cgaggggaga aacgagtagc tgctttcaat
    35641 agtttacttt cgcaatctga aagaagatac gtcctccgtc atctatcgca atataaattt
    35701 ttgtttttga gtcccgaaat gttgactaat ccttctcttt tagagcatct gaaaaaacaa
    35761 aatattgcgt tatatgtagt agatgaggct cattgcgtgt ctcaatgggg agttgatttc
    35821 cgtccagaat atcaacagtt aggaaaaatc cgaaagcttt taggaaaccc ggtcacactg
    35881 gcactaacgg cgacagcaac agatttagta gcaagagata tacgtcatgt actatttgat
    35941 cgaccaccaa aagagatcag acaatcagtc aatcggcaaa atatctcgct ttttgttcgg
    36001 aaaacgcagc aaaaagaaca agaacttgaa cacttcatgg aaagagcaca aggagcggca
    36061 atcatttatt gtgcaacaaa aaaagaagtc gaacgattgt atcatttatt cagggaacgt
    36121 tttacagttg gatactatca cggtggtctt gatgcagctc aaagaagaca acttcaacag
    36181 cagtttgtaa aaaatcagct gcagtttctc attgctacga atgcatttgg tatggggatc
    36241 gataaatctg atatccgtta tgtgatccat tatgatttgc cagacagtct agaaaactat
    36301 gtacaagaaa tcggtcgagc aggcagagat caggaagaaa gtgcagcaat tcttttttat
    36361 caaagtgggg atgaacgtat ccattatttc tttaatcaac tttctagaga acagcgacaa
    36421 agttttgagc tttatttgga atatgccaca gagcaagctc cctttgatga gctgcaaaaa
    36481 aaatggatgg agctgatcca gcagtctgaa aaaccagaaa attgggtgga acggctcaaa
    36541 cgtcaggaaa aagaaaaaga attccgcctg cagcagatgc ttcgctatat taatgaagaa
    36601 aactgccgca gaaaattcat cttagcttat tttggcgaaa aactctccga aaagccgcag
    36661 aattgttgtg atattgatgg agcaaaagca gaacttctgc caaagaggaa gcttttttct
    36721 aagactgaac aacttcattg ggaaacgatt ttactaaatt tatttaaaaa aaacatggaa
    36781 cattgatttt ttaggacaag acactttttc ctatggtata atacacacga tagagtttag
    36841 gaggtaaaac agtgagcaga aaagatagac atcaatctac agaaaataac gaaacacaag
    36901 aaccatggga acaaccaatc tacgatacag atgatgaagt ttcatcaaga agttctcaga
    36961 gacaacaaaa gaaaggaaat acattatttc tttcgctatt tttgatttta ctggtcttat
    37021 gtatcgctat tccagcaggt gcttatttct ggatcagaaa tggatcaagc aacaatgcaa
    37081 cagcagcaac ttcttctgaa acttcgacat cagtagtaga aagttctaca agtacaacaa
    37141 aagaggagtc aactgagact tcaacagtag aatctagtac aatcgcggaa gaatctactg
    37201 tgtctcaaga tacaggtgta acgtcagaaa gcagtattgc agcagagaca acaccgactt
    37261 cctcaagtga ggcaacttat caagcagggg attcaagcag caatgcagca gaaacaacac
    37321 cttcttcatc agctgcagcc ggttcaacaa cgactgttca agcaggcgaa ggtccaaaac
    37381 aagtggctga gcgtgcaggg atcaccactg atcaattgtt tgaattgaat ggcttagatc
    37441 caaacaactt tatgctttac cctggtcaag aattaagaat taaataataa tagccgcgct
    37501 ttgcggcttt ttttctgaga aaaaggagtt atatcatgac acaaatcagt attgcaatcg
    37561 acgggcctgc ttcatctggg aaaagtaccg ttgccaagat attagcaaaa gaattgaatt
    37621 atatttatac agataccggt gccatgtatc gcgcagtaac ttatttagct attacgaaca
    37681 atgtatcttt ttcagatgaa gaagggctag tttcgctgat caaaaagtat cctatctctt
    37741 tttcgcaaca agaagatgga cagcatgtat tcatagcatc aaaagatgtg actttagaaa
    37801 tccgtcaacc agatgtcaca aaagctgttt ctgaagtctc tgcacatgga aaagtcagag
    37861 aagaattagt tgctgtccaa cgaaaaatag gggaacgcgg tggcgttgtc atggacggaa
    37921 gagacatcgg gacagctgta ttaccgaatg cagaagtgaa aatcttttta gtagcaagcg
    37981 taagtgagcg tgcagaaaga cgtttcaaag agaaccaaga aaaaggaatt ccgactgatc
    38041 ttgaaacact gacgaaagag atacaggaaa gagaccatta tgattcaaca agggacgtct
    38101 ctccgctgaa gcaagcagag gatgctgttc gtatcgatac gactggcaaa tcgattccag
    38161 aagtcgttgc agcaataaaa gctgttgttt tgaaaaaagg ttatcttctt ttttaaatta
    38221 agaaaaaaaa tgaaaaacaa ttgttttttc aaggaaaacg aacgaaatcg ctttattttt
    38281 tttgaataat caattaaact aaaaacagta ccgtacttac ggcagaatgt tggttaggag
    38341 gacaagtgtt atgacagaat ttgatcaaaa tcaagagaac aaccagtcaa tggaagacgc
    38401 aatgaaaagc gtacaagaag taaaagttgg cgatgttgtt aagggcgaag ttttagtcat
    38461 tgaagacaaa caagtgattg tcggaatcga aggggctgga gttgaaggag tcgttccggc
    38521 aaaagaatta tcaactttgc cggtagaaga tatcagcgaa gtagtaaaag tcggtgatgt
    38581 attagattta gtcgttatca gtacgatcgg caaagataaa gaaaacggca gctatctact
    38641 ttcaaaacgc cgtttagatg ctaaaaaagt ttgggaagat atcgaaagag atttccaaga
    38701 gggcaaggtc atcgaagcac ctgttacaaa tgttgtcaaa ggcggtttag tcgttgacgt
    38761 cggtgtacgt ggttttgtcc ctgcatcaat ggtggaagat cattttgttg cagacttttc
    38821 agactataaa ggcaaaacat tgagctttaa aatcatcgaa atcgaaccat cagaaaatcg
    38881 tttgatctta tcgcataaag cggtagtgga aaacgaaaga gaagaaaaga aaaaagaaat
    38941 tctttcaact atccatgagg gagatgttct cagtggacgt gttgcacgtc ttactgattt
    39001 tggcgcattt gtcgacctag gcggaattga cggtctagtc catgtctcag agatttcaca
    39061 tagtcatgta gcaaaaccaa gtgatgtatt ggctgtcaat gatgatgtaa atgtcaaagt
    39121 gttgtctatc aatcctgaac aagaacgtgt ttccttgtca atcaaagaca cacagcctgg
    39181 accttggtca gaaatcgata caaaagctcc agttggcaca gtattagacg gaacagttaa
    39241 acgtttgaca agcttcggtg cctttgttga agtgttccct ggagtagaag ggctagtcca
    39301 tatctctcaa atttcacata aacatattgc gacaccacat gaagtgcttc atgaaggtga
    39361 cgaagtgaaa gtgaaagtat tagagatcca tccagaagaa catcgtattg cattgagtat
    39421 caaagcttta gaagaaaaac cagcttcaga agaagaacca aaaaatgttg agtcttatga
    39481 attaccagaa gaaaatactg gatttactat gggagacatt ttaggtgatg cgttgaaaga
    39541 agaagtagaa gaaaaagcaa ccgatgattc tgaaaaataa ttgattttgt atctgtgact
    39601 gagatgaaag cagctgcttt tgtctcagtt tttcttttga aaagcgatta gtatttcaat
    39661 aaggaataaa aatacttcgt ttaattgaca atctatgctt gaaagttggc aatgcattcg
    39721 ttaaactaag tgagattgga aacttgtgag gaggaaataa tatggcaaat ccaacaattg
    39781 caatcgttgg ccgcccgaac gtcggtaagt ctacgatttt taaccgcatc gctggtgagc
    39841 gtatctcgat tgtcgaagat actcctggag taactcgtga tcgtatttat gcaaaaggtg
    39901 aatggttagg tcgagaattc agcgtgatcg acacaggcgg aattgatctt ggcgatgaac
    39961 cttttatgga tcagatcaag catcaagcag aaatcgcgat tgaagaagca gatgtaatca
    40021 tttgtgtagt cagcggacgc gaaggcgtga cagacgcaga tgagatggtt gcgaaaattt
    40081 tatacagaag taataaacca gtgattttag cagtcaataa agtagataat ccagaaatga
    40141 gaaacgatat ctatgaattt tattccttag ggctaggcga tccttatcct gtttcaggaa
    40201 gccatggact agggattggt gatattttag atgaagcagt gaagtatttc tctgaagaga
    40261 ctgaagaaga ggacgacgac acgattaagt ttagtttgat tggtcgccca aatgttggta
    40321 aatcctcttt gatcaatgcg attttaggag aagaacgtgt aattgtttcg gatattgaag
    40381 gaacgacccg agacgcaatc gacacccact tcgtttctga aagtggtcag aaattcttaa
    40441 tgatagatac agctggtatg cgtaaacgcg gaaaagtata cgaaaatact gaaaaataca
    40501 gcgtgatgcg tgcaatgcgt gccattgacc gttctgatat cgttttgatg gtactgaatg
    40561 ctgaagaagg gattcgggaa caagacaagc gagtagcggg ttacgcccat gaagctggtc
    40621 gtggaattat tatcgtcgtg aataaatggg atcttgtaaa gaaagaaacc aatacaatgc
    40681 gtgatttcga acaagagatt cgtgatgaat tccggtatct tgattacgct ccaatcgttt
    40741 ttgtttctgc agtgactaaa caacggttgg aacgtctgcc tgaaatgatc gaacaagtaa
    40801 gtatgaacca gaatcttcgt atctcttcgg ctgtgttgaa tgatatcatt atggatgctg
    40861 tagcaatcaa tccaacacca acagataaag gaaaacgcct gaagattttt tatgctacac
    40921 aagtcgctgt caaaccacct acatttgtcg tttttgtcaa tgaagaggaa ttgatgcatt
    40981 tttcttatga acgtttctta gaaaatcaaa tcagaaaagc atttactttt gaagggacgt
    41041 ccatccgaat tatccctcgt aggagaaaat aggcatttta ccatatcgac gttttttttt
    41101 caaaagaaaa agacagtttc gtttgttacg tttctatgac taaaaaaagc atgtgaaaat
    41161 tggtaaaaac cttgctatta agcggttcat atgatatcgt gataacagaa tattgaagtt
    41221 aatcaatatt tctttttaaa cttctggacc actcagaaag ttttaactaa atgatatttc
    41281 tatcatatct cttgtggagg aggtgaatct atccatggca aacaaagcag aattaatcga
    41341 aaaagttgct tcagctactg atttaactaa aaaagatgca actgcagcag tagatgctgt
    41401 attttcaact attcaagatg ctttagctaa cggcgaaaaa gttcaattaa tcggttttgg
    41461 taactttgaa gttcgcgaac gcgcagctcg caaaggtcgt aacccacaaa ctggtgaaga
    41521 aatcgaaatt ccagctagca aagtacctgc attcaaacca ggtaaagcat taaaagacgc
    41581 tgttaaataa gacagttgaa aaagcgcttg tggctctagg gctacaagtg cttttctttt
    41641 tatttcctag cagaaaagga ataaataaga gacagagatt ccgaatccgt atgtcataca
    41701 tagaaaacac atgtatttta tttaattttt atttatttgc aagttatgag gtgagctttg
    41761 ctcttatctt ttctagaatt tgcttactaa tggtaaaata aaaataagaa gaggagggat
    41821 gcgtatggaa cttgattatc aagtagaaga tgcgttgacg aaagtgtttt acggagaaac
    41881 gctagtcagt cagctaagag aactttccat tgatcagcca atcttatttt taacgaatca
    41941 gcgctattat gatttgtttg cagataagat caacccgtta tttgcaaatc aagcaaacaa
    42001 tgactggtat atttgtgcca acactcaatg caatcattta acagaattaa agaacctgct
    42061 tgatttcgtc aaacgctatc ccgaaaatca atccatgttt atcatcggat ttggaaatga
    42121 agggatcatg gatctggcag gtttttttca aaaacataca acccttgatt catcactatg
    42181 gatgatccct gtatcgatcc gttctctaag ccgagcatta acaccgcagc ggacgatttt
    42241 gcagctacca aatcgtgtag tgctgcaaac catcaatctg ccagaacgca tcgtttatga
    42301 tcaaacaatc agcgagcggc aggtggacgg aaagcagatt gactttttga cttttatctg
    42361 ttgcggaatg atttgtgatc atcgtttttt gcaaaatctg tataaaaact atccaaataa
    42421 aaagcaatta acgactcggc cgtttgccgg gatgatcgaa gaaatgatct atttttatca
    42481 attagaggca gaaaacctgt caaattatgg taaactgttt gaacaagctt tttatctgac
    42541 cgaaaatggc catctacttt ctgctagtat gaaaaaattt ttaggaatga tgtttcattt
    42601 cgtgtggaat ctccaagcat atccttttga tttccaacta aaaaactttt ttgtgtggct
    42661 ggacttgctt ggctatccaa tccactggct ggaacagatt tcaaagatgg agtatttgga
    42721 aaaagttctt tttttggcag aaaaaagcaa aaaaatactt gttttagaaa aaataggtat
    42781 aatagacgga taccaacatc caaacgaaaa agaattattg agaacaatga cggtatttca
    42841 acaaatcgtc agtgagataa gagggaattg aaatgaatac aaatagcgaa aaaatgttgc
    42901 aagctttatc agatgaagac ttgtcacaag cacaaatctt tttagaaaaa gcattaaaag
    42961 aagacccagc agatatatta gctgaactag gcgaagaatt gctggctatt ggctttttga
    43021 tcgaagcaaa acagattttt gaacaactga tcaaccaata cccagaaaat gacggactga
    43081 acatcccgtt agcagaaatt gcaatcgaag ataatgagat cgacttagct tttgaatacc
    43141 tggaaaaagt ggataagcaa agtgattact atccgcaaag cttattggcg atagctgatt
    43201 tgtaccaagt tatcggaatc cctgaagtga gtgaagcaaa attgaaagaa gcagctgggt
    43261 tgcttcctga tgaaccattg atccagtttg cgctagctga attgtatttt tcagttgatc
    43321 gtttcaaaga ggcagcagtg gtttatgaaa cattgttggc aagcgggata aatgaaattt
    43381 caggaatctc gatgcaggaa cgtttaggac aatccttaag tatgcaagga gaattcgaag
    43441 cagctatcgt acctttagaa gaagcactga aagaagaaag gacagatgat cgactgttcc
    43501 agctagcttt tacgaatctt caattgaaag aaaatcagca ggcaatcaac tatctggaag
    43561 aacttcgaga agttaatccg cattatcaat cgttatatct atatctagga caagctcttc
    43621 aagaagaaga aatgattgaa gaagcacaaa cagtgttaga agaaggaatc aaagaaaatc
    43681 cttaccaagt cgaactttat cacctggcct cggaaaatgc tttccgtctg catgatagac
    43741 agcgagcaga agaactttta ctgaaagctt tagaagtagg agacaaacaa gatgaaacat
    43801 tacttacttt aagtaatctt tacttggatg atgaaagata tgaagatgtg atacaagtga
    43861 tcaatcagat ggaagaaact gctaatcctt atgcagaatg gaacctagcc catgcttata
    43921 atgaattaga agactttacc gttgcagctg tacactatga acaggcttat catgaactat
    43981 cacatgaacc agatttcttg aaagagtatg cctttttctt aagagaagaa gggcagctga
    44041 aaagagcgca agaattattg acttattatt taacacttga accaggagat atggaggcac
    44101 tgtcattatt agatgaccta acagagaggt gagaaaaatg ctaattgatg tacgggaaaa
    44161 gaagaatttt ttaacgtgga tggtcaatca tgtatctttt agccgaagag aagttttttg
    44221 gatcttgaat tatcttgcca atcatgaagc gattttaagc aatgtccact ttgttgaagg
    44281 ggcgaatttt gcggatcgag gactgcagat cagtgatcta tctgttgaag gggaacccat
    44341 gaaattgttt ttgcagggaa aagaatttac ggacacagac cagatttttc atgaaatccg
    44401 tttgaattgg aaaaagcctt tatatgtgga atgtatattc gaaaatgctt ggcagacaag
    44461 agaatatcta tctatcttag aagacaatcc attttcttct tgggattctt cagtcagtga
    44521 agaagatact gaattaattg aacgatattt tcaagaaaaa gaagaagagg caaaactaaa
    44581 aatgctttat gctcaaatcg atcaagcact agaagatgga gatagggatg cttttttgaa
    44641 attatctgat gaagttaacc gaaagatcct tttgcagaca caaaagaaaa gtaaccgggt
    44701 aagtgaacat aacaattagt taaaaatagt atagtactaa aaaagacaaa ggtcagctgg
    44761 atgtggaatc tttcctcata gcctatcttt gtcttttttc ttatagtttt ttcagtaatc
    44821 ttgtctgtgg cttcaaataa gtaaagcctt gcccttccac ttcatgcaca ttgatgattg
    44881 aaaggaaagc tttttcgtca atctcgtgga cgatcctctt agcttcagtt aattcactag
    44941 agctaacgac catatagatg attttttttg aattaccaga gaatgcgcct tctccagaaa
    45001 ggaaagtcac acctctttgc agaccggtca tcagtagtgg tgcaatctct tcgcttttgt
    45061 tggagacgac aagtagacct tttgcagaat atccgccatc taagatcgaa tcaatcacac
    45121 gactgaaaac atacgaaaca atcaacgtat acatcatacg tttcaagtcg atataggtta
    45181 atgaagcaag taagacgatg atatcaaatg ccaataggga acgccccata gtgatgccgt
    45241 aattttgttc taaaatccga gcgataatat cactgccgcc tgttgttcca cccatgcggt
    45301 agacgatccc gcttcctaca cctgcaacta aacccgcaag tagagaaacg atcagtagat
    45361 catgctgtaa attgatttct agtggaaccc tttgccagat ccataaaaag aatgacaaag
    45421 aaagtgtacc tagaacagta taggccaagg aacgtttacc gaggatcttt cctcctagta
    45481 aaatcaatgg gatgttgatt aataaagtcg tataagctgg atcaatacca aataaagctc
    45541 ttaagatcaa ggtgatccct gagactcccc cttctgctaa atgattagcg atgttcaagt
    45601 aaacaagacc aaatgcataa atacttgttc ctataatgat aaaaagaact tcttttactg
    45661 tttttcgttt gaccatatga attccagctt tcaattatgt attttcacag aatttccatt
    45721 tagaaattcc ttcctaaatg tagcatggaa attcgatttt ctcaattgct cttatctagg
    45781 atttgcgtta aagttttggt aagatagttt tggagggaaa aagatggata aaaagcgttc
    45841 tttatacagt atgcagcagg aagtggatga atatatccag caattcaagg tggggtattt
    45901 ctctccatta gctcagatgg ctcgattaac tgaagaagta ggtgaattgg caagagaagt
    45961 caaccacact tatggagaaa aaagcaaaaa ggcttctgaa ccagttaact cggtagcaga
    46021 agaacttggt gatgttttat tcgttacgat gatcatggct aattcattga atatcgactt
    46081 aactgaagtt tttgaaaaaa acatggaaaa attcaatcaa agagaccata atcgctttga
    46141 gcgtaaggac gagtaaacaa gatgaagtgg tcctggcctt gaagactctg aaacggactt
    46201 gtcaaacagt caccatgcaa ctgagtcttt atctcaggac aagaaacacg caggaaaggt
    46261 tggaaaaatg aaattaaaac aattacctct ggaataccaa aaggcaattc cagttctgaa
    46321 aaaattagag aatgcaggat atgaagctta ttttgtaggt ggaagtgttc gtgatatctt
    46381 gctgaaccag ccaatccatg atgtggatat cgcaacaagc gcatttccag aagaaatcaa
    46441 acagcttttt ccaaaaacga tagatattgg gatcgaacat ggaactgtgt tggtattaga
    46501 aaatgatgaa caatatgaga tcaccacatt tcggacggaa tcaacttatc aggactaccg
    46561 tagaccagat catgtcgaat tcgttcgttc gttggcagaa gatttgaaaa gaagagattt
    46621 tacgatcaat gcgtttgctt tgaaagaaga tggagaaatc atcgatttgt tcgatggtct
    46681 gcaagatcta gaagaacaga tcttgcgagc tgtaggcaat cctcatgagc ggttccatga
    46741 agatgcctta cgaatgatgc gcgggttgcg ttttgtcagt caactagggt tcaaattaga
    46801 ggaagaaacc ttctacgcca tcaaagaaaa ccacgagcta ttaggtaaaa tatctgtaga
    46861 acgtataaat gtggaattca tcaagatgct cttgggaaat gaacgggccg cgggaatcca
    46921 tgcatttatt gaaacagagt gctacatttg ctgtcccggt ttgaaagaag aaggcgaagc
    46981 acttttacgt tttgctgaat taccatccgt cccattgaaa gaagagagcc aagcatgggc
    47041 attattgatc agccaactgg atctaaaaga aaatgagatt cgttcctttt tgaaatcgtg
    47101 gaagtgttct aaccaaatga ttaaagacgt tcaagcactt gtccaaggac tacgacaacg
    47161 agaaactgga gctttggaac cattcgaatt gtacttctta ggcaaaaaac atgcactgca
    47221 agtagaagaa ttgatgatct attttgacga aacacctcag atggatgccg taggagaatc
    47281 ctatgatcgt ttacctatca agtcattaag cgaattagca gtagatggta aaatcttgct
    47341 agaagaaact ggaaaaaaac ctggtaagtg ggttagtgaa gctttgcaat tagctgaaaa
    47401 agccgtcgta gaacaaagaa taaaaaatga taaaaaacag gttttggatt ttttatcgaa
    47461 agaaaaattg atttaaaaaa cactagactg tatctgctca gctttgttgg ctacttaaag
    47521 tgggcagata cgtcattaga agaaaaaaca taagatgtga ccacttacat aaatttgtgc
    47581 taaactgagg tagtacaaga ataaattaca tcataaagga gtctttttaa tgagtaaaga
    47641 aatgacagcg ctaaaatttt attttagaaa tggagaaacc tggacgatca accgccgtca
    47701 tatcggcgat ctttggatca aacaaatcac aacaagtttt ggacgaatca atggcagtga
    47761 atttgttgaa atccatccgt gtgctggatt taaaatcgaa atcttccatg aaggggacgc
    47821 agttgcgaca catgatatca acctaggcgg actggaaatg ggcatgttta atcgcgcatt
    47881 gaaatacgaa gatatcgagc gaatggaaat cctttaccga aatggcacac ctgatcttgt
    47941 gtacttccca tatctagata aaggaacaga aggattagac aatcaatatc aatcaacaaa
    48001 aatcagcgaa aaaacaggta acttgtatat cgtgatcaat ccagatcaac gtgtagaaga
    48061 tgtatacggg gaatttttcg aataaatcga tttttacgca aaaatgaggc tgtgaaagag
    48121 atgtgtctta ttactactga taggctgtct cttccacacc gtttattcag aataagggac
    48181 tgtgacaaga tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca
    48241 ggaatgggaa agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga
    48301 tatctgatac tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag
    48361 caataaacga tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg
    48421 aagtttgtgt ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt
    48481 tgcatgatcg ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc
    48541 gtaaaagaaa tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt
    48601 tggagtcaaa acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg
    48661 aaaccaaaat tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat
    48721 aaaggggatg gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct
    48781 tatcgaacat agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc
    48841 ttggagtggt attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt
    48901 tcttagttat gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt
    48961 cgattctcaa aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc
    49021 ttgtcggggt aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct
    49081 ttgcttttgg agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac
    49141 gagtgaatat ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg
    49201 catctggtgt tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag
    49261 cagtaaacgc ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt
    49321 tgcttgtctg gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg
    49381 tcacagggta tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg
    49441 catttgatgt atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt
    49501 ttaggaaaat ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa
    49561 ctattgcttt tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag
    49621 tgttctcgcc agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg
    49681 tattaatctc tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat
    49741 tcaaagatgg cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg
    49801 gcggtgtaaa gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata
    49861 atatgatgtt ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga
    49921 ctttggtcat agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca
    49981 cggatttgaa tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa
    50041 aggaaattga tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc
    50101 aagaacggat acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac
    50161 aagaaataca agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt
    50221 cgggcaagct ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac
    50281 attctatcac aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt
    50341 taatgcgaat cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga
    50401 catttattag tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt
    50461 tgattattga aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt
    50521 ttatccagca acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt
    50581 ggatgatcca gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa
    50641 gaaaaatcat tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct
    50701 atcgcaggaa tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt
    50761 ctttccgatt tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta
    50821 aaaattttca agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt
    50881 ctttttttga gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt
    50941 ttatgataca atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc
    51001 tcaaaaaaac ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa
    51061 aagaccgtat cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta
    51121 ttgccggtat cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc
    51181 gtattggtta tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag
    51241 tctttcaagg aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg
    51301 aactagggga aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac
    51361 aaatgaataa agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat
    51421 taggaatcag tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag
    51481 ttagtctggc gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa
    51541 accatttaga ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg
    51601 cactattgat ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg
    51661 aactttcatt tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa
    51721 aagcagaacg tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac
    51781 aggaattagc ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga
    51841 tcaaccgttt cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag
    51901 agctgaacct agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt
    51961 accgtataaa tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa
    52021 gactaggtat tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg
    52081 gcagaattcc cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt
    52141 atacacaaga aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag
    52201 ctgctgaaga agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac
    52261 gatttttatt tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa
    52321 aacgccggtt atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg
    52381 aaccgaccaa tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt
    52441 ttccaggtgc tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata
    52501 agttattagt attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt
    52561 atttactgaa gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga
    52621 gcaaggaacc tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga
    52681 ttgaagatga gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc
    52741 atcaaggaga taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag
    52801 cacaacttga agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg
    52861 aggaaaaagg atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca
    52921 tcgtaaagaa gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt
    52981 tgatctgcaa aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa
    53041 aagcgaattg ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa
    53101 aaaccatatt tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg
    53161 accagatatg actgattttg gccatagatg tttgacagat cctgaattca atgaagaata
    53221 taaaaagcag agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac
    53281 atacggcgat cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg
    53341 tggctttatc gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag
    53401 aagattgatc gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg
    53461 tcatacgatg tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg
    53521 cagtggggat gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca
    53581 cctaattgca catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc
    53641 tcatctttat atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc
    53701 atttccgact ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga
    53761 tatccaatta gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa
    53821 tcagaaagga tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg
    53881 gaaaagaaga ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga
    53941 cagaagcaaa tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt
    54001 tgccgaatcg tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc
    54061 atgtcatgca tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt
    54121 tcatcgctgg agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc
    54181 gtacagtcat ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg
    54241 attggtcact gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc
    54301 aatttgaaac gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga
    54361 tataaaaaag ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt
    54421 ttttttatta agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa
    54481 acaaatgcca aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta
    54541 tcgtgtaaga aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat
    54601 aaagaggaac agcagccacg acacagagcc accccataaa aatatagatg atcgtagata
    54661 cttttgatac tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg
    54721 caaacaacca gattaataca aataaagtcc aacctagcca tcctcggata ctcagcaaac
    54781 aaaaaggagt ataacttcct gcaatcaaaa gaaaaatcga actatgatcg aatacttgga
    54841 acaccttttt tgcttttgta aaaatcaatg aatgaaacaa agtagacgtt aaaaataaaa
    54901 gaatcatcat cgatccatag atagcataag agacaatatg gagggaggaa tgcaagtggg
    54961 caccttttac taaaagaacc actagtcccg cgatactcaa tccagtccca attccatggg
    55021 tgactgcatt aaacacttca tttaatattt catacgttcg attaaatttc gttttttcca
    55081 tgaaaacggc tcctttacta ggtgtaatta atgaaaaatc attatttgtc tgttatacta
    55141 aaaatagaaa ttgtcttaca tgtagtttaa catgaataag gcatcttgtt aaagaaagag
    55201 agagagaaaa taatgacaaa tgtaaaaatc gtaacagatt cttcatgtac gatggaaaaa
    55261 aatgtacgcg atgctttagg cattcgtgtc atgccgctat ccatcatgat cgacggaaca
    55321 gtatatcccg atgatgacca actagacggc gaaagattta tggaaatgat ggcgaaagca
    55381 aaaaatctgc ccaaaacaag ccaaccacca attggagaat tcatctcgat gtatgatgag
    55441 ctaggagaag acggcagtga agtgatttcg atccatatga caaaaggctt gagtggaaca
    55501 gtagaagcag caagacaagc cagtaatcta acaaaaacga aagtaacggt tatcgacagt
    55561 gataccactg accaaggatt atcttttcag gtaattcgag cagctgaatt agcaaaagaa
    55621 ggtaaaacag tagagaaaat ccttgaagaa gtcaaaaaag tacaagacaa tacaaaatta
    55681 tacatcggaa tatccacact agataacttg gtaaaaggtg gaagaatcag ccgaacaact
    55741 ggtttgctgt ctagtgtttt gaacatacgc gtggtgatga atttcgccca ttctgaatta
    55801 atccctgtaa ctaaggggcg aggaaagaaa acgttcgata aatggtttaa taatttgaaa
    55861 aatgaactga aagaattgcc aaatgtgcga caaatcggta tttcacatgc ggatgcaaaa
    55921 gaattggcgc aagaattcaa agagggtttg caagaattat tcccggacat gcatatccct
    55981 gtactgcata cgaatccggt tatcgctacg catactggta aagacgcgtt tgcaatcatg
    56041 tattatgtag attagtcgaa aagaggataa gccctcagcc tgaaaggctt gcagcttatt
    56101 ctctttttct ttataaaatt aggaaaataa ttgttttctt ttttcataaa gactaccttt
    56161 ttgataaaat ttttgataac attagaacca atcgaataca agaggtgaaa aaatgaaatt
    56221 aacgaaacga catttgatcc tcgttttgtt cccattatta attgcgatca tcatctatgc
    56281 aggtttagct gcttctatac cgaaagctgg cccactaatg aaaccagtaa ctactgtgag
    56341 agaagatcca aataaaaaag aaaaacttca ctacatagct atcggagatt cgctgactga
    56401 aggagtagga gatcaaacca agcaaggagg attcgttccc cttgtcgcaa atgatctaaa
    56461 agaccgttat aatttgaccg cggttgaaac agaaaactat ggtgtaaatg gtgaacgaag
    56521 tgaccagatc ttaaagcgag taaaaacaaa agaagaaatt cgaaacaata tcaaaacagc
    56581 tgattttatc acactgactg ttggcggtaa tgatttgatg aaagttatcc aaaataattt
    56641 attcgggtta acggtcaatt cctttaaaaa gccactgaaa aactatcagg aaaatgtcac
    56701 agaactattg gaagaatttc gatccctcaa taaaaccgca cctatttaca ttttaggcat
    56761 ctacaatcca ttttatttga actttcctga gatcactgac atgcagacaa ttgttaacaa
    56821 ttggaacaaa ggaacagaaa cggtgacaaa aaaaatgccg aactgctact ttatcccaat
    56881 caatgatttg ctttatcaag gattgaatca ggaagtaggt gtcacagaag aaggaacaga
    56941 tcaaacaact agcacgacag aaaatctaaa tggcatcaaa aataatgtgc tctatgaaga
    57001 agatcatttc catccaaata atttaggtta tcaattgatg gcaaatgcag tgagagatca
    57061 gctgatcgag acacaaaacc aatggttaga gaaggaggat gatcaataaa catgaaaaca
    57121 agatctgacg tatcttcaaa caaaacaaag aaaacaaatt actggaaatt cgccttcctt
    57181 atccttcttg gggtagtact tggttcgacc gtatttttag gcagccgtat ttttgctaat
    57241 cgggaaccag aactcccaga aataccagct cttacggaaa gacaaggaga tcctgtctta
    57301 acgatcaatt caaataaaga aaaagtcaat caaatcatca gctttttcct tagtgagtat
    57361 caaaaagata gtgatattga atataaattt tatttggaaa atgaagcact actcaatggt
    57421 actttcgaag tactaggttt tcctatcgat ttctatttat attttgatcc gtatgtgatg
    57481 gaaaacggaa atgtccaact aaaagctaga agtctttcta tcggaacatt gagtttgcca
    57541 atcaaagatg tgatgaatat gatcaagaga aactataaat taccagattg gatcgaagtc
    57601 aatacagatg atctgactat catgcttagg ttggatcaat tccgaatgca aaacgggatg
    57661 tatattaaag cagataaaat cgacttagta aatgatgaca ttcggtttag tctatatttg
    57721 ccaaaagata cctctgatgc ttcaaacaac tcaaatacca acaaaactag caccagcagt
    57781 actgaaagca agacaaaaga aaataaaaaa tcatcggatg agtagtatta gagggggaat
    57841 cataatggaa cgagcaatat ttgcaggagg ctgcttctgg tgtatgatcc agcctttcga
    57901 cacgcttcct ggtatccata cagtgatgtc aggatatact ggagggcatg taccagatcc
    57961 gacttatgaa caagtaaaaa gccaaacgac tggacataca gaagcagtgg agattatcta
    58021 tgatccaaca ttgatttcat atgaacaatt agtagaactt tactggcagc aaactgatcc
    58081 aactgacgct ttcggacaat tcgaggatcg cggtgacaat tatcgcccgg tgatctttta
    58141 tttgacagaa gaacagcgga tcattgctga aaaaagtaag aaacagttag ctgaaagtgg
    58201 acgtttcgaa cagccaatcg ttacaaaaat cgaaccagcc caaccatttt atctagcaga
    58261 agaagaccat caagagtatt ataaaaagca tcctgaaaat tttaaaagaa accatgcacg
    58321 ccgggctgcc tttatcgaag aaaattggag gaacgaaggg tgaatcgaag cttttttcat
    58381 tatttaatga cactgcgagg cggtggcaca catgatgctt tatctgtttt cgctacagaa
    58441 gccggtaaag acatccaatt tcctaagcac agctctagct acgaagaaat ttctaattat
    58501 ctggaactga atgtcgacta tttgccgtcc atggatatct ttgacgaagc atgggaaaaa
    58561 tatttagaaa ataatcatga catataagag atagttttgt actttatgat caaaaaagtt
    58621 ttttgtccaa tagcctaatt gaaagaatta tttttatttc agctatctag tcgcattttt
    58681 ttgatatttt tcttataata aagaaagaat gaaaaaaaga gggatggatt gatagagatt
    58741 gacaaaaaaa caacgctata ttaatcgctt ctggcttgta ttcaaatact tacttgtttc
    58801 tgtattcctt gcgttcatgt tgcggggatt tttattcatc ccggtaccag tggaaggcaa
    58861 ttcaatggaa aacgtgttga agcaaggtga tatggttgtg atggaaaaat tttcggagat
    58921 cagacgattt gatattgttg tttttcaatt agcagatggc acgatttata tcaaacgagt
    58981 aatcggtctt ccaggagaaa atgtcagcta ccaaaatgat caattgaaga tcaatgggaa
    59041 agtagttaag gaaccttatc taactaaaaa cctgaaatca gatcatgcaa atgcatccta
    59101 tacgacggac tttacactac aagagctaac gggacaatcc aagcttccgg aagataatta
    59161 ttttgtactt ggagataatc gaagagtttc aaaagatagt cgttcgtttg gcacgatcaa
    59221 taaaactgat attctaggta aagcaagatt tgtctattat ccacttgatg aaataaaatg
    59281 gatccagtga gaaacaataa agcgtgcagt ctgttgagac tgcacgcttt attgtttaat
    59341 ccaaaatcag tttactacct tagtacgtaa aatcaaacag ctcgtttaaa cacttttcta
    59401 gcctctaaag ttttgataaa tgaataaaca accattattt gaatagggat ttggatcata
    59461 ttcctgatga atctacctag aaaaattact ttgaaatctg caccaaacaa aacagacatc
    59521 agccaagaat tgataaaaag gctgactggg atcataatca ataattgggc agcgatgacg
    59581 gaaggcaggt ttatcttttt atgatataaa aataagccat taataaatcc accaaggaaa
    59641 gccgtgataa gaaaagcagc ttgaaacgtt cctgaaccaa atatcgtgaa atttaaagtg
    59701 ttcgacaaca tttcaagcaa accagcccag atcggtccat atagataacc cataagcgcc
    59761 atacttaaaa atccgaatgt gatttgaaaa taagcaggac caatcgctat cttgtataag
    59821 atgacatcaa gggctaataa aagagcagag gtcgacaaca atcttgcatt catttcgggc
    59881 aatctaaaaa cgtcttttgc aatcaaagtg ttcaaaatat tctctccttt gtcagttaat
    59941 aataaaagga taccataaaa tcaccaatgt gtcatgacac attggtgatt tacatacact
    60001 ggcatctaac aattaaaaaa agggtgagaa gactgctttt ataaactgta aaaaagagat
    60061 tgtacgaata aaaaaaatag aggcggagaa tacttatcgt atcatccgcc tttgtttttt
    60121 tgttataaaa aacgtcagat tagttatctg cttacatctt catccatacg ggttctaatg
    60181 tatttccgtc tagatcttgg acttctaatg aaaacatttc ttcttcaggc attcccatat
    60241 ctacttcgtg gaaagtacca ccattttctt ttgcaatttg agcaaatttt tttacttcat
    60301 ccgcattttc aacactaaac gaaatcaaag caccacttgt ttttttatta tcagctattt
    60361 ctttatcttt tataaatttt ttataaaaat catgagagag aagcattatc caaaaagtgt
    60421 catcccatac cattgaacca gcttcttcag tagaaaattc ttcatttttt ttaaaaccca
    60481 gcttttcata aaaagcaacg gaacgattga catcagcaac aggaaaatta acaaaaacca
    60541 tactattcat ttgtttcgtc tcctttctgt tttgttcgtc tatcatctct tatttaggaa
    60601 acgctgtcaa aaatttagat tcatatatag aaaccaaaat aaaaatttgc atcatcaaaa
    60661 aagtgaagat gtgatagaat gaggactggt tcactttcac ttaactaata gatggaattt
    60721 ctttataacg ccgattgtaa aattaagcta gacaactaaa aaagtcattt gtgctacact
    60781 caaaatagtt ccgtccaaag aattataagg agtgagtaca aatgacctat acccatctta
    60841 caacggatga acttgtaatg atagagtctt atttcaaaat aaatcaatct gttgcgaaaa
    60901 ctgcgcattt cttgaatcgt tcaagacaaa cgatccataa agtatacctg ttcttcaagc
    60961 aaggaaaatc agccttagag tactatcaac agtataagaa aaacaaatca aactgtggta
    61021 gacgcccgct tgttttacct gaggaacaat cagaatatat tcaaagaaag gttgttcaag
    61081 gatggacacc cgatgtgatt gttggtcgtg cagcgtttcc tattcgttgt tctgctcgta
    61141 ccatttatcg tatgttcaaa aaggggctat ttaatccttc tgacttaccg atgaaaggca
    61201 agcgtaaacc aaatggacat caagaaagac gtggaaaaca agctttccgt cgctctattc
    61261 atgaacgtga aaaagattat agccaattct caaatgagtt tggtcacctt gaaggtgaca
    61321 ctatcgtagg tttgaaacat aaaagtgctg taattacctt agttgagcga ttatcaaaag
    61381 ttatcatcac attgaaaccg tgtggtagac aagcgattga tattgaaaac aaattaaatc
    61441 attggtttga atctgtaccg aaaaatctat tcaaatccat cacttttgat tgtggaaagg
    61501 aattttcaaa ttggaaacag atcagtaatg ccaatgatat tgccatttat ttcgctgatc
    61561 caggaacgcc gtctcaaaga ggcctaaacg agaattctaa cggattgt
//
LOCUS       DAXLPY010000009        56722 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.009, whole genome shotgun sequence.
ACCESSION   DAXLPY010000009 DAXLPY010000000
VERSION     DAXLPY010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.009"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(80..598)
                     /locus_tag="ACF3UF_000647"
     CDS             complement(80..598)
                     /locus_tag="ACF3UF_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFD3670802.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(600..1217)
                     /locus_tag="ACF3UF_000648"
     CDS             complement(600..1217)
                     /locus_tag="ACF3UF_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFD3670803.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(1214..2068)
                     /locus_tag="ACF3UF_000649"
     CDS             complement(1214..2068)
                     /locus_tag="ACF3UF_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3670804.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(2065..2976)
                     /locus_tag="ACF3UF_000650"
     CDS             complement(2065..2976)
                     /locus_tag="ACF3UF_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3670805.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(3017..4351)
                     /locus_tag="ACF3UF_000651"
     CDS             complement(3017..4351)
                     /locus_tag="ACF3UF_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3670806.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            4559..5389
                     /locus_tag="ACF3UF_000652"
     CDS             4559..5389
                     /locus_tag="ACF3UF_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFD3670807.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(5633..5882)
                     /locus_tag="ACF3UF_000653"
                     /pseudo
     CDS             complement(5633..5882)
                     /locus_tag="ACF3UF_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6073..6267)
                     /locus_tag="ACF3UF_000654"
     CDS             complement(6073..6267)
                     /locus_tag="ACF3UF_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670808.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(6772..6957)
                     /locus_tag="ACF3UF_000655"
     CDS             complement(6772..6957)
                     /locus_tag="ACF3UF_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670809.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(7807..8148)
                     /locus_tag="ACF3UF_000656"
     CDS             complement(7807..8148)
                     /locus_tag="ACF3UF_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFD3670810.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVIRPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(8148..8378)
                     /locus_tag="ACF3UF_000657"
     CDS             complement(8148..8378)
                     /locus_tag="ACF3UF_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3670811.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            8674..9012
                     /locus_tag="ACF3UF_000658"
     CDS             8674..9012
                     /locus_tag="ACF3UF_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670812.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPIQIET
                     LVQRISTREDFAIVECEIVAIFVEEGILHDPTHINVDKWQPLIYKLREYTTANQSLSL
                     NFRFQEFKES"
     gene            complement(9217..9792)
                     /locus_tag="ACF3UF_000659"
     CDS             complement(9217..9792)
                     /locus_tag="ACF3UF_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006974 - DNA damage response [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HFD3670813.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPEQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGF
                     YEWNEEKDKFMFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRMPLVL
                     TEEQIEPWVTDVSFARKIITQQMPELVMEKV"
     gene            complement(10157..10738)
                     /locus_tag="ACF3UF_000660"
     CDS             complement(10157..10738)
                     /locus_tag="ACF3UF_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3670814.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASETGKGQFYYYFS
                     SKKEVCLAVIHAHMVVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWIKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(10921..11547)
                     /locus_tag="ACF3UF_000661"
     CDS             complement(10921..11547)
                     /locus_tag="ACF3UF_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFD3670815.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFSLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(11569..12897)
                     /locus_tag="ACF3UF_000662"
     CDS             complement(11569..12897)
                     /locus_tag="ACF3UF_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFD3670816.1"
                     /translation="MEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTCI
                     NIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARFL
                     SNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPEK
                     LVIIGAGYIGLEFASMFNEYGSKVVVLDAHPEFLPREDEDIAQMILEDMTNAGIEFHL
                     GVSVDQVADQESTAAVTFTENGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDRG
                     AIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVPY
                     SVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETDL
                     ILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(13056..13457)
                     /locus_tag="ACF3UF_000663"
     CDS             complement(13056..13457)
                     /locus_tag="ACF3UF_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFD3670817.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(13543..13749)
                     /locus_tag="ACF3UF_000664"
     CDS             complement(13543..13749)
                     /locus_tag="ACF3UF_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670818.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(13844..15346)
                     /locus_tag="ACF3UF_000665"
     CDS             complement(13844..15346)
                     /locus_tag="ACF3UF_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFD3670819.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(15364..15819)
                     /gene="argR"
                     /locus_tag="ACF3UF_000666"
     CDS             complement(15364..15819)
                     /gene="argR"
                     /locus_tag="ACF3UF_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD3670820.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(15917..16534)
                     /locus_tag="ACF3UF_000667"
     CDS             complement(15917..16534)
                     /locus_tag="ACF3UF_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFD3670821.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            16755..18128
                     /locus_tag="ACF3UF_000668"
     CDS             16755..18128
                     /locus_tag="ACF3UF_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3670822.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            18203..19315
                     /locus_tag="ACF3UF_000669"
     CDS             18203..19315
                     /locus_tag="ACF3UF_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3670823.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(19387..21024)
                     /locus_tag="ACF3UF_000670"
     CDS             complement(19387..21024)
                     /locus_tag="ACF3UF_000670"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFD3670824.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(21192..21800)
                     /locus_tag="ACF3UF_000671"
     CDS             complement(21192..21800)
                     /locus_tag="ACF3UF_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3670825.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(22184..23335)
                     /gene="queG"
                     /locus_tag="ACF3UF_000672"
     CDS             complement(22184..23335)
                     /gene="queG"
                     /locus_tag="ACF3UF_000672"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFD3670826.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(23354..24106)
                     /locus_tag="ACF3UF_000673"
     CDS             complement(23354..24106)
                     /locus_tag="ACF3UF_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670827.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(24247..25197)
                     /locus_tag="ACF3UF_000674"
     CDS             complement(24247..25197)
                     /locus_tag="ACF3UF_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFD3670828.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(25198..26037)
                     /locus_tag="ACF3UF_000675"
     CDS             complement(25198..26037)
                     /locus_tag="ACF3UF_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFD3670829.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(26034..26780)
                     /locus_tag="ACF3UF_000676"
     CDS             complement(26034..26780)
                     /locus_tag="ACF3UF_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3670830.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQPVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            27018..28388
                     /locus_tag="ACF3UF_000677"
     CDS             27018..28388
                     /locus_tag="ACF3UF_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3670831.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(28443..29339)
                     /locus_tag="ACF3UF_000678"
     CDS             complement(28443..29339)
                     /locus_tag="ACF3UF_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3670832.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(29453..29623)
                     /locus_tag="ACF3UF_000679"
     CDS             complement(29453..29623)
                     /locus_tag="ACF3UF_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670833.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(29620..30297)
                     /locus_tag="ACF3UF_000680"
     CDS             complement(29620..30297)
                     /locus_tag="ACF3UF_000680"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFD3670834.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(30388..31293)
                     /locus_tag="ACF3UF_000681"
     CDS             complement(30388..31293)
                     /locus_tag="ACF3UF_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFD3670835.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            31468..32922
                     /locus_tag="ACF3UF_000682"
     CDS             31468..32922
                     /locus_tag="ACF3UF_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFD3670836.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            32938..33969
                     /locus_tag="ACF3UF_000683"
     CDS             32938..33969
                     /locus_tag="ACF3UF_000683"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFD3670837.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            33976..35163
                     /locus_tag="ACF3UF_000684"
     CDS             33976..35163
                     /locus_tag="ACF3UF_000684"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFD3670838.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            36113..37975
                     /gene="ltrA"
                     /locus_tag="ACF3UF_000685"
     CDS             36113..37975
                     /gene="ltrA"
                     /locus_tag="ACF3UF_000685"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFD3670839.1"
                     /translation="MENVSASHSIRHMEYYGLIDSFDSLYKESSENKIFSNLMEIVTS
                     PNNILLAFRNVKGNSGSTSPGVDKKNIDDLKAIPNIEFIKTVQTKFSEYKPQPVKRVD
                     IPKPNGKTRPLGIPTIWDRIIQQCLLQVLEPIMEAKFHDKNYGFRPNRSAHHAFAQAV
                     RMAQLSKLTFVVDIDIEGFFDNVNHSKLIKQFWTLGVRDKWLLGVIRAMLKAPIIHRD
                     GRIEHPKKGTPQGGVLSPLLANVVLNELDWWISSQWETHPTRKNYDCYHQTRKQWIKS
                     NKYRALRASKLKEIYIVRYADDFKIFCRKRSDADKIFLATKLWLKDRLKLDISAEKSK
                     VVNLKKQKSDFLGFTMKLVRKRKSFVIETHMCAKAMSAASNKLAKQIKVIQHSPTQVE
                     LQKQLSIYNSMVVGIHQYYKKATHISVDCPRINQRLMIIIKNRLDIKRKGPPPSDFIK
                     KNYARSKQLRWLNGVPMLPFGFIKHSHTSLPKIGTCKYTPEGRVLIHRYLTFPIDIIN
                     QLMNMSNPNESIEFRDNRVSKYSSQVGRCRVTKEVLELADIYCHRIVPKNLGGKDNYQ
                     NLVIVHRNIHSLIHEEDKTRASLLIQNMRVTSAQLEIINQFRKKAKNRELSLNL"
     gene            38089..39387
                     /locus_tag="ACF3UF_000686"
                     /pseudo
     CDS             38089..39387
                     /locus_tag="ACF3UF_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
     gene            39359..39745
                     /locus_tag="ACF3UF_000687"
     CDS             39359..39745
                     /locus_tag="ACF3UF_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670840.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(39945..40613)
                     /locus_tag="ACF3UF_000688"
     CDS             complement(39945..40613)
                     /locus_tag="ACF3UF_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFD3670841.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(40802..41599)
                     /locus_tag="ACF3UF_000689"
                     /pseudo
     CDS             complement(40802..41599)
                     /locus_tag="ACF3UF_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(41880..43259)
                     /locus_tag="ACF3UF_000690"
     CDS             complement(41880..43259)
                     /locus_tag="ACF3UF_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3670842.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSVSDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(43435..44604)
                     /locus_tag="ACF3UF_000691"
     CDS             complement(43435..44604)
                     /locus_tag="ACF3UF_000691"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD3670843.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPKHVKQAGIAAIEEDFSHYTGMRGLEELREAACMFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(44579..45730)
                     /locus_tag="ACF3UF_000692"
     CDS             complement(44579..45730)
                     /locus_tag="ACF3UF_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFD3670844.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSGAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFHYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSRSKEERVYNDEFIQSI"
     gene            complement(45690..47051)
                     /locus_tag="ACF3UF_000693"
     CDS             complement(45690..47051)
                     /locus_tag="ACF3UF_000693"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFD3670845.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYSKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(47048..48049)
                     /locus_tag="ACF3UF_000694"
     CDS             complement(47048..48049)
                     /locus_tag="ACF3UF_000694"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFD3670846.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(48065..48760)
                     /gene="dapD"
                     /locus_tag="ACF3UF_000695"
     CDS             complement(48065..48760)
                     /gene="dapD"
                     /locus_tag="ACF3UF_000695"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFD3670847.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAGTVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(48766..49482)
                     /gene="dapB"
                     /locus_tag="ACF3UF_000696"
     CDS             complement(48766..49482)
                     /gene="dapB"
                     /locus_tag="ACF3UF_000696"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFD3670848.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(49479..50360)
                     /gene="dapA"
                     /locus_tag="ACF3UF_000697"
     CDS             complement(49479..50360)
                     /gene="dapA"
                     /locus_tag="ACF3UF_000697"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFD3670849.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(50363..51163)
                     /gene="dapF"
                     /locus_tag="ACF3UF_000698"
     CDS             complement(50363..51163)
                     /gene="dapF"
                     /locus_tag="ACF3UF_000698"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFD3670850.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDTDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(51150..52409)
                     /gene="lysA"
                     /locus_tag="ACF3UF_000699"
     CDS             complement(51150..52409)
                     /gene="lysA"
                     /locus_tag="ACF3UF_000699"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFD3670851.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKERSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(52624..52794)
                     /locus_tag="ACF3UF_000700"
     CDS             complement(52624..52794)
                     /locus_tag="ACF3UF_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670852.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEREETALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(52895..53458)
                     /gene="efp"
                     /locus_tag="ACF3UF_000701"
     CDS             complement(52895..53458)
                     /gene="efp"
                     /locus_tag="ACF3UF_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFD3670853.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            53886..54803
                     /locus_tag="ACF3UF_000702"
     CDS             53886..54803
                     /locus_tag="ACF3UF_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFD3670854.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            54816..55961
                     /locus_tag="ACF3UF_000703"
     CDS             54816..55961
                     /locus_tag="ACF3UF_000703"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFD3670855.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPHHELHGVAKQQMSGFSGMISFTLKNEETAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            56132..56590
                     /locus_tag="ACF3UF_000704"
     CDS             56132..56590
                     /locus_tag="ACF3UF_000704"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFD3670856.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
BASE COUNT        16471 a        11589 c        10220 g        18442 t
ORIGIN      
        1 acaactacgc tttcctcgaa acaaaaaaat aaagcacaaa tgcgcattta cgcactcatg
       61 ctttattcgt acaattaatt cagataacgg cagcgcatag gatgccaata acacttccta
      121 aaatagctcc tcctaaaatg tcagtaggat aatgtaaaag taaaaaaatc ctcgaataag
      181 cgatcaaaca agcaaataaa aaggctaata ttcctgcaac tggacttaat tcgaacaacg
      241 cagctactga taaaaaggct agcgctgtat gtcctgaagg aaaagaagaa gtcttcggtt
      301 tacttgtgta aaggacaagc cgacgatttt tttcataagg tcttttccgt cttgtcgttt
      361 ttttgataaa aagcaaacca acaaaaaaat agatcaaact gccgataaga atggctagac
      421 catattctct agtatcaggt atcaagacta aaacagcagc aaggagcaac caaataaaac
      481 caccattaga gatattactg ataaatttca aaaaattgat ttttcgacta tccgttttcc
      541 gttgcttggc gaacttgttg ataatactat catcgatttt agcaatcaaa cgcaacatgt
      601 tattcctcct ttttaagaac cttttcttgc gtacgatgga taaaaagcag gacttgaaaa
      661 taaaacaaga aactgaaacc taataaagca aaatagattg gtcctgcaaa ccagaatgcg
      721 acaagaagga tcaacgtgcc tgccaaatag aaaagcgcgc ttttgaaatc attaaaaaac
      781 aagaaaaatg cagtaatcca agaagcttct ttttgttcca gttgaagcaa gattttgtaa
      841 ctaaagagaa gcgcgcttaa tagaagcaaa aacaacgtag tatacatcaa tgtatagcca
      901 attcccccac cccaatagcg gaaaatctga taatcgatca atagaagaag aaaataaaca
      961 cttgctaaac tatcttgctt tccataaaga gagaagttct cacgaaactt tttccagaat
     1021 agtgaaccga gctttttctc ttcatttttt ttgtaatgat aaatcatata cagaactgtt
     1081 cgacttgcag ttcctaatgt gaaaacaggc aagacgcaca ggaaccatag tagctgtaaa
     1141 tggataagac gtggaatcca ttcaatgatt tctaagaaat aatcattggc ttttttacca
     1201 atcgatcgat tcatcatcct tttgaacctc ctgtcaaatc catcccttca atgaaataac
     1261 gttgtgcaaa aaagaacagc aaaatcgtcg ggatcaagac aagtgttgct cctgccatca
     1321 gataattcca ttgtgtcgtt gcttggttct gaaaaacttg caagccaatc tgtaacgtgt
     1381 atttttcttg atcttggata tataacagag gacctaagaa atcattccaa gctgcgttga
     1441 aggaattgat cgcaatggta atcaaggcag gtttcgtcaa tggaagcatc aaatgactcc
     1501 aaatatacaa atgattcgct ccgtcgattt cagcagcttc gatcaattca ttattgatcg
     1561 ataagtaaaa ttgacgcatc agaaatatat tgaacgcatt gccgaagaac gatggaacga
     1621 tcaggggcaa ataagtacct acccagccga tcttggagaa taatacatat tgagggatca
     1681 tcgttacaaa ccccgggatc atcatcgtag aaagaaccaa agcaaacatc agctttttcc
     1741 caggaaaatc aagcttcgca aatccataag caataaaaga atttgaaagg acattaccga
     1801 tcactactag cacagtgatg aataatgtat ttcttgcata gcgccaaaaa ggaaaggcgg
     1861 caatcgtatc cagatagttt tcccatacga ttttttctgg gaaaaaggtc ggaggataac
     1921 gaacgatttc ttccattggt ttcaatgaag taaacaccat ccaaagcaat ggaatgatca
     1981 aaatgattcc tattactgtc atgaggacat aacttagtat tttttttgtt tgccgattca
     2041 cactggtctt tttgaaataa tccatcattt gccgtcacct ccagaataat agacccactt
     2101 aggtgcaagc ttcaaattga caaacgtcag aaccaacacg atcagaaaca ggatcattga
     2161 catagccatc gcataaccca tatcaaaagc tacgaacgcc ttgttccaca tatgcagatt
     2221 ataaaaaagc aaagaatttg caggtccgcc tgttccattt ttcgtcatga cataagcttc
     2281 ttgaaaaatt tggaaagaac cgatcgtaga ggtgatcaca tcgtaaaaaa taataggagt
     2341 gattaatggc aaagtaatac ttttgaactt tccccaaacg cctgctccat cgatttctgc
     2401 tgattcatat aaagatctag gaacattttg taatgtagct aagtaaagta gcattgctcc
     2461 tccagaactc catattttca tcaaaatcaa cgcaggtttc gtccattgtg gatcaaacag
     2521 ccaagctggt ccagggatat ggaaccagcc cagaaatgtg ttgatcaatc ctgcagatgg
     2581 agaaagcagc tgcatccata agatgtagac tgctactcct gataagactg ccggtaaata
     2641 gaaagctgta cggaatacac tgattccttt gattttttga ttgagtactg tggctaaaaa
     2701 cacactgaaa atcgtcgtca gcggtacatt gaagatgacg aaataaacgg tgttgtataa
     2761 cgatttccaa aataaatcat cgtgaacgaa cattcttttg aaatttgcta gaccaatgaa
     2821 attcatcttg gatgtcaaat tataatcggt gaaactacca ataactgaaa aaagcatagg
     2881 ccctagcata aataccaaga acccgataat aaaaggcgag ataaataaat aggcccatct
     2941 tgcttctttt ttctttcgga tagataaacg cttcaaattt tcttgcctcc tctgtaccta
     3001 gacagtcaaa aatggattat tgattttgct tgactaagtt ttctactgct ttttgtgcat
     3061 ctgccaatcc ttcttttggt gattttgttc ctaaaagaat ctggtcaatc tgttcattca
     3121 ctaatgtcgt gtaatccgga gcatctaaag gaactggtgt gatcaccgta tttttaaagt
     3181 tttcgtccgc catttgatag atcatttttc ctttatccgt taggttgtca ttattcacta
     3241 aattctcatt ggctgtcttg ctcgccatga tatcaaaact tttttcgccg aatttttctt
     3301 gtacttctgg agaagaaaga tatttgatga attcataaga ggcctcagga tcttttgctc
     3361 cgtatggtac ttccaagacg aatccgccac cccacgacca atggcctgaa ccttcttctt
     3421 tttctgggag ctgcatcacg ccaaaatcaa aatcatccgg tgcattttcc atcaaactag
     3481 agtaataatt gatattttgg gcacgcatgg ctactaatcc ggaaataaat ggatcagata
     3541 caccagaccc aaattcggct tctaatttat tgatcgtatt tttcccataa taatcttgcc
     3601 agtcttggat ccactccaag gcttccactt tatttttagt atcaatcttg actttttcat
     3661 ctttgtcaaa ccaactagtc ccgttatctg cgtttagcgc ccatacatca gcccctaaat
     3721 tccataatgg ataaaaaccg atgcgtgtaa attcttttcc ttctttttta tctagtttac
     3781 gtgctgtttc ttctaattca tcccaagttg tcggtagatc ttgttcactg attccagctt
     3841 ctttaaataa ctttttatta taaaaaatga cttgtgtatc tgtattgaat gggatcgcat
     3901 aaggatcacc ttcatattct actgtatccc aaagctgcgg ataaaaatcc ttagaagtgt
     3961 ctttttctac atatttggag agattagttg cttgctgtgc ttctgctctt tgggcaacgg
     4021 aatttatgtc ctgtacaata acatcgggtg catttccagc tgttattgca gataaagatt
     4081 tagtccagat gtcaccccat ggctgatact tataatttac atggatctcg ttttgtgatt
     4141 gattgaaatc ctcaatgatt tcttcgatag cttcttttcg tgcaccggat ccccaaaagg
     4201 accagaaatc aatatttttt cttccatcac ttgttttttc agaagaattt gctgcacttg
     4261 aactggcatc gcttgcatta cttgatccgc atcctcctaa taaaaacaat gctgaacttg
     4321 ccagcaaccc tgtaaacaat aattttttca tattttacct ccaaatttta atgtaaccga
     4381 tgccggtttt aatataacga tatcattttg ttctgaaaat aacaatttat aaggtatgat
     4441 tctaaaaaaa ttattaatga taccaatact ttatataatt cgcgagcgct ttctttgaat
     4501 tttttaatct ttcgtagcag aatgagaatg tattaaaaat agattaggag gaattttgat
     4561 gtttagacac cagaaagaat tgcagtttga agcaaaacca gatcgtccga atccattaat
     4621 cgcgaaatat ctgcaggagc tgatcggcgg ccaatatggc gagatgagtg tagctatgca
     4681 gtacctgttc caaggctgga gctgccgagg agaagaaaaa tataaagata tgctgatgga
     4741 cattgcaaca gaagaaatcg gccacgtgga aatgttggcg acaatggttg ctcgtttatt
     4801 agagggtgcg cctgttgaag atcaagaagc agcgatgcaa aaagatccaa caatcggtgc
     4861 cattatctct ggaatgaatc cacagcacgc gatcgtagct ggcttaggac ctcgtcctgc
     4921 tgacagcgtg ggcaatccat ggagcggtgc ctatatcatt gcgagtggca acttgttagc
     4981 agactttaga gctaatttaa atgccgaatc acaaggaaga cttcaagtag cacgtattta
     5041 cgaaatgatc gatgatcgtg gcgtaaaaga tatgctgtct gttctccttg caagagatag
     5101 ctatcatcaa aatctatggg aatgtgcagt gaaagaatta gaagaaaaag aaggttcaat
     5161 cttagtccca agtactttcc cgcgtgacaa agaacgaaaa gacattgctt atgacttcta
     5221 taacttctca gagggagacc aaagtagtga aggttcttgg gctagtggca aagcactgga
     5281 tggcgaaggc gaatatcaat ggttgaaaga acctaagatc gaaggcgctg caccaaaatt
     5341 agaaccagta acaccaaaaa tgtatgggac acctccattc aagaaataaa tatctacccg
     5401 tagaaacacc cgttttttgt tccacacgct ttgtgagcaa aactgactaa agtcattaat
     5461 cataaccacc cttcaaaagg gtggttttct ctagagctat aagctcaaat caccggccag
     5521 cgcctaaaga cgctggcttt catattttat gttcaagcca tattgccttt gccagttttg
     5581 cccacctctt aaaaggttta tgtactactc cttagccctt aaaaggatcg tcttactctc
     5641 gtacactcag cttatctaac gcactatcat gtttttcttg ttcttgaatg tactttttga
     5701 tggtcgcttc attttgtcct acttttgtca catagtatcc ttccacccaa aagtgtcgat
     5761 acccaaattt atattttaga tttgcacaat ctcttgatga tctcctgaat attggctcga
     5821 tattgattat aaattatttt tcttctatac tttggtgtga atacaatgtg gtatttacac
     5881 atctactttg tacgggctaa actatttccc tttattgctc cacccgcata gcaagtggtt
     5941 ttgtatttca atcgctcggc gcgctcaatt aggtctaaag acaataaatc taaaaacccg
     6001 ctgcttcact gacagaaaca acgggttttc agaaaaaaat gaaatgaaaa agatctctta
     6061 cggcaatcta ttttattttt ttgatttttt ataaatggaa aatgcttcaa gaagtccaag
     6121 aaataaagcc gtataaaaac aagaacctat gaaatcttta tttattagat attcaacaga
     6181 aatcccgata acactagcca acaatatatt tatcagaagt gtaaaataag gatgcttttt
     6241 atagaataga actagtgttg ttttcataga ctctcctttc ttcatatttc caattaatca
     6301 caaattcacg gcattactag aaaaattaaa ggggcgcaga agtggaaaaa tactcttcga
     6361 ctttccctac aaaccaggcc atcttgtgtt taataactat accaaatcta aggtacctct
     6421 aaatctaaat tccatttgtg gcggtgacct ccaattttta actcttctat ctcccatcca
     6481 gtatacataa ccttgatact tcgaccactt atatatcgaa cacacaaata cctatccatt
     6541 gcaggagtac tacctaactt agttgctact tgcatctaaa taacagctga aaagatagga
     6601 cttactctta gtaaagtatc tgaactatta atttttaaac tatcattttt atcctcaact
     6661 acatgcacat ctgttgcaac ttcactttct gtctcatcca gataaatgat taaggaatcg
     6721 ggaattgcaa tatcttcagc tgacgctgga atagttgagc taaattagtc atcatatctt
     6781 tattataaaa taaccaacag caaaaaatac aatgaaaaac aaacttggaa ctaatgtatc
     6841 attaataaat gttgaaaaat tcagcaactc attactgtat gattttagca gcccaaccaa
     6901 catataccct ataaaagcta ataagatggt taggaatcct ttagaatttt tactcattca
     6961 tagacacttc cttaaataac ttttattata gaaggtattg taaataataa tattgacaaa
     7021 aagtgactca aaataaaaaa aaacttacat tatactggaa tgaactgtat tgatagtgta
     7081 cctaaaagct ctactgacat aagatcgtgt aatcggtaaa gtaattttat taattatacg
     7141 ggatgtaatc aattagagaa taaactaatc ataaaaggta cttttacatt cataattgtc
     7201 gctttgagat tctactttgg ttcactatct gacccaattg cacattttcg atcattacaa
     7261 gtattggtgt cgttagaaca actaaataaa aactagcggt agatttttca gaatctatgc
     7321 taatttctgt atggatgttc cagtgatggc aaatttctct tttcattgtt tttcttgtcg
     7381 catgatatgc ctttttgtgt tattcagtta aactatagaa attctttcct agacagatct
     7441 tgatcccaaa ttttacgttt ttgagcatcg atatagttta aaatgacatt actcatatct
     7501 aaagagttta gattttttag gactaaaact gtcagttgtt ctttttcttc tttctgttaa
     7561 agtattgtcg cgacttttcg tatacgttaa gatatgtcgt gaaaaaacaa gttttgtgac
     7621 acaaaaaaac gaatgacttg aggaaatcac ctcaatcatt cgtttaaaat gctatatatt
     7681 ctttagttta agatacggaa attaatgcca tcgaccacac tagtagaatg aacgacattt
     7741 acttggcctt tttttaattt cgttatgttt agcatataaa aatattatag agtttactta
     7801 caatgcttaa aacatatact gtataatctg atcaatttta gccatgtctt gcaatggtaa
     7861 gttttctatt tttttgagtt ttcgttcctt aaaatcaaga gattttaatt gtgtaataat
     7921 tacttgtcct tttatatcta gctcttcagg taatgagtaa cgtgtcggta aattctttat
     7981 agtggaagta attggacgta tgaccgaaaa cattgtttta cggttaaatt cataacgaga
     8041 gacgactagt cctggtcgtc ttttttgaat ttcttttcct acggagggat caaaatcaat
     8101 ccatacaata tcaccttttt taggaatata aattctttct tctgacacta taaaatttct
     8161 ctcccttcag gagttaaatc ttcccattcg tctttctcat aatactcggc ctcttcccca
     8221 ccactaaatg gatcttcaat ttttggaact aacgtaattg ttccatcatc agaatacaca
     8281 acgatatatt cttggttttc tgaaggtttc tttccgttat cagaaggtaa agttaccact
     8341 acagaacttc cttgtaatct agattttgta acaagcatta tcatcactcc cttaataaaa
     8401 gtatactata taacactaag taacgcaaaa ttcccctttg taaactatct agaaaattgt
     8461 tttgtttaaa gtatatctta ttggatataa atagaaataa attgtagcca gttcattttt
     8521 tctttaaata aaaaaataat ccaagaaaca ttgaacctat ggatccaaaa gctacccaaa
     8581 tactatagct aactccccgc taccttcaat cttgcagata aaacgctttg gaaaaaaatc
     8641 gagaaaatcg caaagacgac aggccatcct atcatgcctg attataaaca aaaagctggc
     8701 tattcctttt gctctgacaa atttcaattg ggaaagttca cgaaactagc aggtgaagaa
     8761 gtttcaactg ttcggattaa agaatgcccg attcaaatag aaacgttggt tcaacgaatt
     8821 tcaactagag aagactttgc tattgtagaa tgtgagatcg tagctatttt tgtagaagaa
     8881 gggattttac atgatccaac tcatatcaat gtggataaat ggcaacctct tatctataaa
     8941 ctcagagaat atacaactgc caaccagtcg ttaagtttga attttagatt ccaagaattc
     9001 aaagagtcat aatgataaac atcattaggt ataaataaaa aagactcgca gaacgagtaa
     9061 aaaacaaata gaagctatac cttagaaagg tcgactgtga ctctatagat gcagtatatg
     9121 cagcttatga gcatttcttc tgttctcttt gtttttggga tctgtgctga agtctttttc
     9181 gttttttgcc gctctttctt tgaaaaatcg attatgttat accttctcca ttactaattc
     9241 aggcatctgt tgagtaatga tttttcgcgc aaaagaaaca tctgttaccc aaggttcgat
     9301 ttgttcttca gtcaagacaa gcggcattcg gtcatggatt ggtgcgactg tgcggttagg
     9361 ttcagtagtc attatgattg attctgccat tttttcatcc tgatggctac gataaaaacc
     9421 gccaatatac actatttttt ccttatttga aaacataaat ttgtcttttt cttcattcca
     9481 ctcataaaag ccactcattg ggaaaacaca acgattttgc aaaaatggtt gatgaaaggt
     9541 ctttttttct tctactgtct ctgcacgggc attaatcatc aattgtcctt ttttaaatcc
     9601 ggtaaatccc cacttcatga tttccggagt gaggatgttt tcttcctctt ttcttaacgt
     9661 cacaacaaga tttgacggaa aaacttctcc agctgctaat tctgctgcct gctccggttg
     9721 tttcgtctgg gcttctcgat aataattctg aaggagctct gactctagat caaaaaaata
     9781 acgaccacac atcctaatcc ctcccaatct ttttttctat catacactgc aacaagaagt
     9841 ccgtaccaac aaaacgcttt caatttgtgt agaactaaaa aagttgtgac aagtgacaaa
     9901 ctctccagtg aatggtattc tcctgccaac tcctcggtca caagtcacaa tattcaacaa
     9961 acatgagaag ctgctttttg aaattgttcc ttgtgactcg gagtgaaacg gcaggcttac
    10021 gacctctagg taaacggtgt tccagaagta gcttcttcga aaaataagcc gaaatttcac
    10081 aaaaatttga gaagcaattt tcgtaaattc cttcttattt cttgaagctg accacttctg
    10141 tcacaacctc taattattaa agaacctttt gcgaagttaa caatctttct ttgatcaatt
    10201 gaaaattttg tctaagtagt gatagatcct gtgtgacttt caacaataag atacttccct
    10261 ggatttcagc aatcaacgct ttggcttgac ggtctgcttc ttcatcggac agtttttctt
    10321 cagaaagtgc caggatattt tgtttcgtat acttgatcca ttgattgact aattctagta
    10381 gcaacagacg gtattcttca tccactgtac tcaactcaat aatcaaatta cctacaggac
    10441 agccatgata agtgatctgt gtctcatgat cagcaaaaat ccagtccaac atttcttcta
    10501 atgcttcttc tggctgtttt ccagcattta agatgtcttc gaacaattct gtctgccaca
    10561 cgaccatatg cgcatggatc accgctagac aaacttcttt ttttgaagaa aagtaataat
    10621 aaaattgccc tttccccgtc tcagaagctg ctagaatatc tcggattgac gtttcatgat
    10681 agcctttttt ataaataaga tctttggtcg cttccaagat cttttccttt gttttcaatg
    10741 atattctcct ttttcatttc tcatagtcct atattataca ataaattcat cattttttct
    10801 tcttaatcgt ttaaaaaaga ctgtgccaaa ttatctgaca cagccctcac tataaaactg
    10861 ttctcatata gctagatgtt cattgattca agaactgcga ggacaaaagc aattcctatc
    10921 ttatgatagt tgctctaata cttcctctgt tgtcatcact tgatctgcaa taaagccaaa
    10981 gttcgtcaac gctgcatcca ttgcttcttg accaggagca ccaattgcat ctgtcgctac
    11041 cacaacattg aatccactct ctaccaattc acgcatatgg gaatcgctac acaagtttcc
    11101 gttcattcca ccaagaatca ctgtgtcgat tccatttttt ctcaattgga gcgccaaatc
    11161 attgctttct ggtccaaaga ttttatgagg agagctgata atcgtatttt catccaaata
    11221 tggtttcaat tcttcgatga aatcagctcc tgaaccttct tcaactgatt catattgact
    11281 tttcctagca aacatctgtt gctcaagcat catatgttct cctgcaccgc caaattgcca
    11341 tttatggtca tgtgggtaaa aataatgagg agaaataaag agtttgtatc ctttttcttt
    11401 tgcttgtttc accatttcga tcatgttttc gatcgtattg tatttttcta agatatcttt
    11461 tgtcaaacta aagccaccgc ctgctggttt caagaactcg acttgcgggt cagtgagaac
    11521 tactgctgta tttttattat tgaacatggt ggattctcca ttcgttattt attttaatac
    11581 atcatttaaa gcttcactca ttgttggatg agaatagatt tgatctctca ataacgtata
    11641 aggaagtttt ccattcatag ctagcgaaat caagttgatg acttcatgag aatcttccgc
    11701 atagatactt gcccctagaa tcaagtcagt ttcagggtcg actaaaactt tgaatacacc
    11761 tttaggatct tctaatactt gtgctttagg gacaccgctt gtcatatact tgaataattt
    11821 gtaattgacg ccttgtgctt tggcttgttt ttctgttaaa cctacattgg ataaagtcgg
    11881 agtgataaat acactgtaag gcacagcttt ccggttattc gttgttcgtt tattctcgcc
    11941 cttcaactga tccataatga ttcgataatc atctagagag atataagtga actgcaatcc
    12001 gcctttgacg tctccaatcg cccaaatgtt gtctgcatct gtacgaaggt attcatccac
    12061 agcgattgct ccgcgatctg ttagtttaac atctgtattt tctaatccaa gtgatgctgt
    12121 acttggtttt cttccagttg cagccaaaac ttttgacgct tggattgtta cttcttggcc
    12181 attttctgta aaggtgacgg cagctgttga ttcttggtct gctacttgat ctacagatac
    12241 acctagatgg aattcgattc ccgcatttgt catgtcttct aaaatcattt gcgcgatatc
    12301 ttcatcttca cgaggaagaa attcaggatg ggcatcaaga acgacaactt tagatccgta
    12361 ttcattgaac attgatgcaa attccaagcc aatatatcca gccccgatga tcactaattt
    12421 ttccggtaat tgttcctgat ccatcgcttg cgtagaatca atcaagtagc gacttgtatt
    12481 caatcctttg attggtaaaa tgattggttc agaaccagta ttgatgaaaa tccgttcgcc
    12541 ttcaacaatc actttttcac cattattcgt cacttcgatt tgatggttag aaagaaaacg
    12601 tgctgtaccg tccatcactg tcccagttgc ctcatcgctg atcatatgat aatttttggc
    12661 gcgaagcatg cccgtcaatt tttctttccg agcaacagcc tctgtaaagt cgattcctct
    12721 ttctccattg aaaatcaatg atttagaagg aatacagccg atgttgatac atgttccgcc
    12781 atacatacgt gttgactttt caacgactaa aaccgattcg ccttttgaag ctaacgcctt
    12841 cgctaaagtc ttaccgccct ttccaaaacc gatcacaata ttttgatatt tttccatcct
    12901 ttttccctcg cttctttttt tacctaccga ttggtacaaa aatatgataa ccgataattg
    12961 tctattctcc aaatcatctg ctttatttgt caaaaaaaac cagacaaaaa gcggtccttt
    13021 cacgttttta gtctggttcg atttccttta ttcttctaaa caatcgttac ttctacatcg
    13081 atatttcctc tagttgcttt ggagtaaggg cagaattcat gcgcatcttc tgcaattttt
    13141 tgggcttctt cttcgctgat gccatcgata tgcacttcta atactacacc gatctgatag
    13201 ccgccatcat ctaaattata aagagagaca cgtgctttta ctgtggactc tgctgtcatt
    13261 cctgcttctt tgatcatatg ttgtaccgcc ccattgaaac aagaagcata acctgctgca
    13321 aataattgtt ctggatttgt tccttctgca tggattcctg gaggagtgat tttcatatgc
    13381 atcgagccat ttggtgcctc gacttctcca ttgcgcccgc catggttgat cattgctgtt
    13441 tcgtatgctt ttttcattgt actgctcctt tcgattgacc atttgctact tggctataat
    13501 tatagtgtat gacaagtaag gcgctttcta caaaaattct gcttattcga ataccagaat
    13561 gccgtcttct actatttttc caaaaaacaa aaaaatacta ctcgtgaaca acagcgtcat
    13621 atttgttcca aaataaatag caatcttttc tacataatct tttatatgat tgattttaag
    13681 atacatatat accagaaagt tgaccccata aaccaatact gttaaaaaaa taaccatatt
    13741 cgttaccatt ttttcctcct tttgctggtc tccctaccag cactcgattt aaccatacca
    13801 ctttttttgc cgtccaagca actagccttt caaaaagact ggtttattct gctgttaatg
    13861 attcaagatc agaaaaatgt ccgaataatt ttgctaattt tactaacgcc aacttgttct
    13921 ttccgaattc atcattttct atctgtaata ctagtaacgg ctcatgtaag cttaaacgga
    13981 tcaaaaacca gccgtttccg tatggctctt ctagatcata tcgaatacct tcttcatttt
    14041 ccgggtcgaa gttcatccct ttttcttctt ccaacagtcg cttcatttct tctaatatct
    14101 tgtttccttg ttcgcgtggt tcatcgctga acaattttaa tcggatttct tgtacttcta
    14161 cgggctgttt caactctttg atttgttcat ctaatgtgat accttttctt tttaattctg
    14221 gcaaaagcat caggatcttt gcgatgacat atgcaccatc atccagaaaa tagttttcct
    14281 tgaatgcagc gtgtccgctt gtttcgatgg ctagctgtgt atctttccca agacggttaa
    14341 gttctaatgc tttattgatt acatttcgat agccggaaat ataacgaact tggatgcctc
    14401 ctttttcttc aatgaatctt tgtagatgag aagaagtagg ggaattcgtc acgattcttg
    14461 ttcctggatg ctcttttaat acgattgtac ttaatactgc gatcaaatta tttcgattga
    14521 tcactgttcc agaagcactg acaactgcag aacgatccac atctgtatcg aaaatgatcc
    14581 caagatctgc ttcatttgct aaaacagcct gcttgatact ttccatcgct tctttattat
    14641 caggatttgg gatatgatta ggaaatcggc catctggttc caaaaattgg gaacctgttg
    14701 aatccgcacc taagctattc aatacttttt cagcaaagaa tccaccagca ccatttccgg
    14761 catcaacaat gattttccaa ccatttagtg gtttgctttc tagtgttcca atcccctttt
    14821 taatttttgt gactaaatct tgcgcataag gtgtcaaaag gtctgctttt tctacgcttc
    14881 cagtttgttc gctttttatt ttttgctgct gtgataggat aaaagcaata tcttcttttt
    14941 ctgctcctcc ttctgaggta aagaatttta ttccattata ataataggga agatggctag
    15001 cagtcagcat aaccgcagca tcgcacgaga actgttcaaa ttgagtggac ataaacatag
    15061 caggcgtagt agctaattcg aaatcgatga catgtatccc ttgttctttc agactttgga
    15121 tcaacgcctc tttcagtgct ggtccgctta tcctactgtc atgaccaatc ccaatcgtcc
    15181 attttttatt tggatcggtt gatttcttct ttttctttat ccagtttgct agtccccagc
    15241 cgatcttttt taccatgtct gtcgtcaagt ttacttcata tccttcaact ggtaatgcga
    15301 ttcctcgaat atccgatcca ttttgcagcg ctttcatatc tttcatataa aagtcctcct
    15361 catttattcc ctcatttttt ccagcttttc tgcaaatcgc tgtgcttctt cttctgagcg
    15421 gcaaataata atgaatgtat ctacaccggc catcgttccg acaacttcag ggtaagccac
    15481 ttcatctagc caattcgtta ccacatcggc accatttcgt tcagtcaata cgataaccat
    15541 gaactgaaca gactggatac gcaaaacctc gcgtctaatt gctgtacgca aacgttcttc
    15601 atttaaagaa acagatggct ggttaaataa tgtatagcgt actattttgt tttcattttg
    15661 actttttact aacttcattt ctcgaatgtc tcgagaaatc gttgcttgag tcacatcggc
    15721 gcctgcttca tgcagccgcg caagcagctc ttcctgtgtc ccaataggtt gttctgtaat
    15781 gatctggcgg atcagtgctt gtcgctgttt ctttttcata ttagacacct ctcaatgttg
    15841 attatagcaa aagataagta atatttcttc atattttggt attttttact tttatttttt
    15901 gttttcattc aggttgctaa cctttttcta ttttaacacg caaaatcgtc ttcatttttt
    15961 caggtgctga ttttcttgga tcgctgatgt aaatctcttt gtgttcttta gaagctcttt
    16021 catagccttc ttttgcgatg aatgcttcta atttctcaaa cgttgctggt tcttcggcat
    16081 agggcccgac gtgtaagatt tgggcacaaa gaccttcttc catctttttg aatactactt
    16141 gttctttcaa gtcttccgga agtttgctag aacgctgaat ggcttcttgt gctatcgctt
    16201 ctgtaacaaa gtcaggctgt cggatcatca attgataaga aaaatgttct tttttcatca
    16261 ctggttcatg caaatacttt tcttgcagtc cccattgtcc ttccagtgga tagacagtat
    16321 acatctgata atcaggaatc agccaatttt ttttaggcga catgcgtatt gcatagctga
    16381 ctgcatatag acaggctact cttcgtttaa agtcttcctg attcgggtcg ccgatccctc
    16441 tgatgctaaa gaatgatttt ttaggaacct ctagtatttg cgggcttttt ttcatactat
    16501 agctcttgtc tttacgccat tcaatttttt ccatttttct tcctccgcga aattccattt
    16561 agttatttat tatcatacct ctttttgagt gacttggcta atcgtgttga cactattttt
    16621 cagtttgtgc tagaataagt gaagtaaata aatcgtacag ataacacgtt tcggcgtgtc
    16681 gagagagagg cggtttctat ttttataata gaaatcactc tcttttttta cgaaattttt
    16741 tagaggtgat gtaaatgaca aaacaaaaac agctgctttt agtacctgca gtaattgcaa
    16801 cagggatgat gtcttttgcg ggcgtattga tcgagacggc catgaatgta actttcccaa
    16861 ctcttatcag acagtttgat ttaacgactg cacaagtcca atgggtaaca acgatttatc
    16921 ttttgatgat ttcgatcatt gttccgctgt ctacttattt gaatcgcaat tttagtctca
    16981 aaaaactctt tttagcttca aatctgcttt tcttggcagg tataatgatc gatttcttct
    17041 ctcctacctt catggtccta ttgtttggtc gattgctcca aggtgcagcg acaggtatcg
    17101 ctcttccgtt gatgttccat attatcttga catttgcccc cctcaatcga cgaggcgcga
    17161 tgatgggtgt cggtactttg acaacggcca ttgctccagc aattggcccc acttatggag
    17221 gcattatgac ttcacatttt acatggaatc atatcttcct gtttcttgtg cccgttttga
    17281 ttctttcttt gattatcggc tggtttgcta ttcccgagat ggcagtacaa aaaagtggtt
    17341 atttggattg gataagcgtt ttaggaattt gtcttttgtt tagtggaagt ctaacatttt
    17401 tgagtacgtt gggaacagtt tccagctgga ttgctttaat catcggcggt attggctggt
    17461 tcctttttta ctatcgaagt aaaaaagtgg agcatccact gatccgactg tctattcttt
    17521 caaataaaac attccgcttg tttttgattg gcttcttagt ttatcagttt ttattacttg
    17581 gtgtatcttt tgtcttgccg aatttccttc agatcgttca aggaagtagt ccttttgtcg
    17641 ctggattagc gatgcttccc ggcgcagcgg ttggtgcttt gctttctcct ttttccggga
    17701 aaatgctgga tcaatatggt ccgaagaagc caatttttgc tgggctgatt ctttctttga
    17761 ttggttggct agcattattc ctactcatag gacacgcttc agtgggtgta ttgattgctt
    17821 gtcatgtgtt ttatatgatc ggtatcggat tatcttacag caatatgatg accaccggaa
    17881 tgaatgcact gaatgaagaa ctacaaggag acgggaacgc aatgttcaat accttgcagc
    17941 agttttctgg cgctgtggct acttcattag tagcggtcat tatcaattac gtccagcatc
    18001 atacttccca taactatgaa gtgtctacta cattaggatc aaaagcagca ttaggcgtct
    18061 tgttgctgtt gcttctcgta agctttgctc gattcgccta ttatctgttc tttgctaaaa
    18121 aagcgtagat tccatatacg gcaggtgttg catctgccgt ttttttgtgt gaaaatggtt
    18181 gtttgtaaaa ggaggctttt ttatggaaaa aattgccatt atcggtggcg ggatcattgg
    18241 tatgacccta gccagttact tagatacatc aaaattcaat gttgctttat ttgatgaagg
    18301 gacaggacag gcaactaaag ctagcgctgg gattatctcc ccttggttgt cgaaacgcag
    18361 aaacaaacaa tggtatcgtc tggctaaaga cggcgctgct tttttcccta aacttataaa
    18421 agatttccaa cttgatcaaa cgatttacgc acaatcaggg acacttttgc ttcgacctga
    18481 aaaagattta gctgaattgg ctgttcttgc cgagaaacga aaagaagaag cgccagaaat
    18541 tggaaacatc gaatggcttt cacctgaaca gacatctcaa gcacttccgt tattgaaacc
    18601 agcagtttca ctgcgtatca gtggtggtgg tcgtctggat ggaaaagcat atttagaaca
    18661 tcttggtcag cgtttagcac aaaaacaaat ggagcagatc caggcaaaag tcactttgca
    18721 taagaagagc gattcttggc tcatcaaggg accgtttgga gaatacacag ctgatcgtgt
    18781 aattttgaca cctggcccgg cacttaagcc tttattacaa gaattaggct atgctgcaga
    18841 tatacgtccg caaaaagggc agctcttagc atttcagaca tcttataaga tgagtcaaga
    18901 ctggcctgtt gctatgcttg acggagaagc tgatttcatt cctttcatgg atggaaagat
    18961 ccttttaggt gctacccatg aaaacgatca aggctgggat ttggctccta ctagcgaagc
    19021 ttataaggga ttgactaaga gtacagaaca gttcttgact gatccagatc agataaaaaa
    19081 ctggccatac gagttccgtg taggtacccg tgcttatacg tcagattttt ccccattttt
    19141 cggcgtactg ccagatgatc caagcttact ggctgctagc ggtctaggct cttctggctt
    19201 gaccacaggt ccttatatcg gctatctatt agccaacttc ttaaatactg gtcattggcc
    19261 tacggaagat tatcaaaagg acatctccac ctatattacg aaaaatccat catagaaaaa
    19321 cagctttttc aagtaaggat cccgagcgat attgcgcatg gattacttct tgaaaaagct
    19381 gttattttag ttcaatttct gaatcaaatt ctccaaactt tcttttgctt catctggcaa
    19441 gagatctttt cctatctgag cttcaatgaa tcgtaaacga atatcaagtc gttgtttcac
    19501 cagattttta taggacgtat cctcaaaaga aacaggaaaa tctggtatag gtaaatagtg
    19561 gatgtcttca aatggaccaa acgacttgaa ttctgccgtt tgttgcacga ttctttcaac
    19621 gattgacaat gtcgtttcag gtttgatttt tttatcatcg aaatatccag tattcaggac
    19681 atagcaggct gtttgctgtt tcaaaaacaa ctctcgaaaa gcttgatagt cttccctaag
    19741 aggatagaca cggaaaggat tagcaaatgg ttcaatgact agctcatcta gctgtctttt
    19801 tgtagtgata ttttccgcgt ctgatcgttt tgttgctaat gttgcaccaa aagacgctgc
    19861 taaaactggg tcattgatct tgataattgg cggaagcgaa tcatctttca tgatccaaaa
    19921 aacagcatcg atcttttcgc taagatgatc gactcggtcg ggtgtcgcat aacgtgattt
    19981 gactgtccgc ccatttccgt ttcgtatatc tcctgttact aggacttttt ctcctttact
    20041 tgtacatgtc acgcccacat tctgacaagt aaggaaagaa gaaatggccg gatcatcaga
    20101 cggatagtct tgtgttttat caaagtaaga aggttccaag gcagtagcaa aaccattttt
    20161 tcgagaaata acgaaagcat cgtcatgcaa gatcgaaaca gagtgacctt ccgtatgttt
    20221 tgctaaggta atcgttgatt ttccagaacc ggacaaccca aatacagcca tcgtataggt
    20281 ctggtcatta ctagcatatt gtttcatccc accgtggcag gcaataaagc cattgcgatt
    20341 tcccaatgcc caagcaagcg tcaaagtcgc tttttttaat tctccaaagt aacgtaatcc
    20401 tagcacagcc gctgtattat ggagagcatc aaacaaaatg agtccatttg gaaatgtttc
    20461 atgtgtccat tcgggatcac aaaagatata aagatctccc tcatcaaagg aaacagactt
    20521 ttgataagtc tctaagatct tcgaattcgc tggctgaaaa ttcagcaaat aagaatacaa
    20581 attgttctca aatccttctg gaatcagcaa atgactttgc acagaaaatt cttcagatag
    20641 gccaacgatt acttttgtat ggtaaaactg gcgcttgcga ctttgataca cagcttctct
    20701 taaaattttc tcgtatttgc tttgttcctt gtctaagtcc tcaaagatcc gccgagcact
    20761 tgctgttctt cccacaatgc ttccatcatt gaatactagt gtcctaacat cagctggtaa
    20821 atctagttct tcagcatgtg agattgttaa atctgtgatg atcgttcctg gactcccttt
    20881 tgctagttga taagctgtct tcctatcaaa aacttcatga acattattac cgtaaaatgt
    20941 cgtttctaca atcgatcgaa tactggataa cagtggattt ccacttgtga tttcgtttaa
    21001 ttcgagactc tcttttgtac tcatggctcc tcctcattcc ctaaacaaaa aaacgttttc
    21061 tttattatac attattcgag tttttatttg tactgctgcg ctgtgggaag caaacgagtt
    21121 atttttcaca caaaaaaacc gagaacttga ataaacaagt ttctcggttt catcattttc
    21181 cttttatcgg cttagtacca gccgtttgct aaccagaatg ttttagcagc atcccatgaa
    21241 ccataacgag atgttacata ttgttctgct acacgttctt gattggcagc tgaatagtcg
    21301 ccgtttaagt atgaagcatc taattgataa cggccgatgt aacgtccgtt agtagctgtg
    21361 tatgaaccgc ctgattcttt ttgtgcgatc cattcttttg cagagcttga agttggcgct
    21421 gttgcagcag ctggggcagc aggagctact tcaactgttt caacaggtgc aacgtatgta
    21481 tgttcttgcg ttgctgtttc agttgtagat gctgtatttt ctgttgtttt gttttctgtt
    21541 gttgctgaag aatcatttga agttgggatt gttaattgtt caccaacata aatgcggttg
    21601 atgtttgcga tcgaattttt ttcagcaatt gcatcgatca ttgagttgtc tcctgcaaat
    21661 ttttgtgaga tcttagataa tgaatcacct gattttactg tataaacttc atcagcgtga
    21721 gcatttgtag ttcctacaaa cattgcagta gcaccagcag caaaagttgt acctaaaaca
    21781 attttcttaa atgaattcat attaaactcc tttttttctc cgttttttat tctttcgacg
    21841 ctattaactt tatcatttag aaatatttca taggtaaaag aaacatgaca tttaatgaca
    21901 aaataacgaa ttatttaata tttgtaacat ttaaacaaat atttttttga tacaaaacca
    21961 taaaagcctt gttgtataag caaagtaatc gtttttctat gtttttttat ttttgaatga
    22021 aaaacgcaga ttctgtaaca ttcactgcaa taatccataa aaaaaagcaa aaaaattttt
    22081 gatttttatc aaattctctt aaaaaaatgt aaaaaataca aaaaaaccag taattgttac
    22141 aacaattact ggacaaaaac tttgaataat gttaactatt tttttatttt aactttctcc
    22201 gcaataattt ctgggcatgt tccaattcgt ttataacgac ttcttctgtt tctttagcta
    22261 atatttcatc taatacatca agccattttt ccggttcttt tgttcctaga cgtccaatag
    22321 cccaagctgc tgttcctctg atgacagggc ggacatctgt taaacattct gaaatctcag
    22381 gcaatgccgt tcgatcacct agattagcta aagcaatcaa tgcgtttctc tgcaaaggtt
    22441 tcttcccacg ccatgaacca gctaaatgcc caaattgctg tttgaagtct ttattagaca
    22501 tcgaaagcat tggctttaat tttggatata tttcgtctac ttttggttcc atctcttcat
    22561 gaaaatgaaa atcttttcct tgattgtaag ggcagactaa ctggcagata tcacatccat
    22621 aaatgacatt tcgcattttt ttacgatatt cttccggcat catccctttt gtctgagttt
    22681 gataagacaa acatcgctgg gcattcattc ttccgtcacc aagcaatgct tttgtcggac
    22741 aagcagtcac gcagcgcata cagtcaccgc aaccaaattc tcctggttta tcaggctcaa
    22801 atacaatatt agtaacgatc tcaccaagat agacaaatga accgaactct tcagtgatca
    22861 acaatccgtt tcgtccaata aatcctaaac cagctcgctg tgctacagcg acatcgatca
    22921 gttctccagt atctacttgc ggagctagac gccattcctc ttctttttgc catttttctg
    22981 ctcttgtttg gatgaattcg atcaatcggt tcaaacggtc tctgagtata tcatggtaat
    23041 cgatccccca agaagcacga gcaaactgcc cgcgtttttc atccctaggc acttcttcat
    23101 ggatcctagt aggatacgca agtgcaatgg aaatgatcga tttcggctga tcaaatgtca
    23161 tttctggata aagacgctca tcgatatttg gatgttcaaa gccagaagta tggccagctg
    23221 ctttttgttc ttccaacgat tcttttaatg aatcaaaagg ttccgccgtg gtgaacccga
    23281 ttttgtcaat tcctaatcgt ttgctttctt gtatgatttc ttcttttaat gtcatggtct
    23341 tcctcgcttg ctgttaacgg ctgtataacc cataatatag tttttctttt ttcagctgga
    23401 caaactggat ctgctgatcg gcaatcttct tttcttccat ccattttttt cttgcagcaa
    23461 atacttccca ataatttgtt gaaattaatt ttcttttgtt atctaatgca ttaaaaaaat
    23521 tcaatgaaac tggttttgta cttaacagtt catggagcct tacctcttcc catggcgaaa
    23581 actcagacag atcgcgggaa tacaatactt cttcatagag atttttttgc tgtgtgtacg
    23641 tgaatgtttg cgggattttc ccaggcctag caatttctac tagacgatta taaaacatat
    23701 tcattaattt gctgttggca ataaattgac ttttataata ggccgactgg atctttttga
    23761 ttactccttc tgctttgatg actgaaaata atgcaggcca tgctttgacg gttatttcgt
    23821 cgttttgttt aactaatacg ccaggtgtga agccgactgg agaaaggaac acaaaataac
    23881 cgataccggt attttcatct aaaggctgaa attcatcaaa caaccatttg cctatgtaca
    23941 gctcttcatc tggttctgtt gtctcatttt gatttgctat gaataattta gctaattctg
    24001 cttcaagaaa ttgaaggtct tgatccttgt cggtattttc ctgctggctg atcaatcgaa
    24061 agacttcttc tttaatcgta tatttatctt tacgtgtaaa attcatagcc acaccttcct
    24121 tccttactct aactataacg gaatttcttc aaaaaaggta tctgtacgac gaaaaacagc
    24181 ataatttttt ttcatatctc ttataaaaaa tgcaaggtct gctcctcaag ctagaccttg
    24241 cacttttcag ctttcttttg tttgtgacaa accttcatgg atcgtttcaa tattccattt
    24301 catcatctga tagtaagaat ctccttgttc tccttctttt gctatggaat cagtgaacag
    24361 tttatcatag attttcaaac ccgtttcttt tgctacccgt tccatgcttc ttgagtctac
    24421 actggtttcc acgaataaaa ccggtacttc ttttgctctt atctgatcaa tgatcgcttt
    24481 catttgatca ggcgtacctt gactttctgt attgatctcc catatataag ctgctggcaa
    24541 atcatatgct cgtgaaaaat acttgaatgc cccttcactt gttactaata attttttgtt
    24601 ctcttcgata gaagcaaaac tttccttcgc ttgtgtatct aattctttta gtttttccac
    24661 atatgcttct gcattttttt tatagagtgt cgcattttct gcatcttttt cagagaatat
    24721 acgtgcgatt tcctccacat attttattcc gttagatagg tctagccaag catggggatc
    24781 tgcttttgta tgttcttcac cgctagttaa ataaagaggt tctacatttt tgctaactgc
    24841 aaaataatct tttccttctt cttttttagc cgtttccatc aagttatcga accagctgtt
    24901 acctgtttca agattcaaac cgttgtataa aataacatct gcatcgcttg cctttttgat
    24961 gtcttctggt agtacttcat attcatgcgg atctgttccg actggtacga tactgtggat
    25021 atctatttga tctgttccga cctcttttgc catgtccgcc aagatcgaat tggtagccac
    25081 gactgacaac ttttctttac ttccttcatc cgcttggtca gaagcctgct ttccgcaacc
    25141 ggctaatacc aagaaactaa ctgccaagat taaaaagagt gatttttttg ttttcatcta
    25201 tctgcttcct ttctgaaata aaattccttt tgttggagaa aataaaaaag caaggataaa
    25261 aaatgcggta catgctaaca cgatcgtagc tcctgatggc caattgtaac tataactgaa
    25321 aaacacaccg acaactgcac ttagcatacc gattcctgca gctgtaatga tcattttcag
    25381 taaatggttc gttagcaagt aagccgtggc ggctggtgtg atcaacatgg caatcaccaa
    25441 gattgttcct actgtctgta aactgactac agccactaat gtcaaaaaga acatcaaaag
    25501 ataatggatc agcgatgtgt tcagcccata agcttttgcc attgtcggat cgaatgatgt
    25561 gatcttcaat tctttataaa agaaaaagac aaatatcaag acgattccac taacgagtgc
    25621 tgtcagcaac aaatcgcttt ccctaacagc taagacattc ccaaataaaa tatgatacaa
    25681 atctgtcgca ctctgggcat atgaaatcaa gataatccct aatgcaaaaa aggagctaaa
    25741 gacaattcca atcgctgtat catttttcaa tcggctccgc tgagtcacga aaccaatcac
    25801 tgctgctgtt agcatcccaa aagcagtggc tccaaagatg taactaaaac caaacatata
    25861 agaaatggct acacctggaa gaactgcgtg agagatagcg tctcccatca aagacatccc
    25921 tcgtaaaata ataaaagaac cgatgactcc agaagcaagt cctacaagca tggaagtgac
    25981 caaagcgtat tgcaggaatt gataattcat taatccatca ataaaggatt ggatcatttt
    26041 ttctctcctc cttttactaa atgtctgatg atctcaccat aggccaattg aaggttcttc
    26101 gatgtaaaga cttcttgtac tggaccggaa gcgatcagct gtttatttaa aagaataacc
    26161 tcatcgaaat attcttctac tttatgaaga tcatgatgga cgatcaaaat cgtttttcct
    26221 gaattcttca attcctgcaa gatgtcaaag atctttcgtt cacttaacgc atcaatccct
    26281 acgaatggtt catctaaaaa gatccattct gctccttggg ctagagctct tgcaataaaa
    26341 actctctgaa gctgtccacc cgatagttcg ctgatctgtc ttttggcata ttcttccatc
    26401 cctacttttt tcaaagcttg tcttgcacgt tctttttctt ttttcccagg tctttgtcca
    26461 attcgtaaag atggatatgt tcctaaaagt acaacgccta atacatcaat tggaaaggaa
    26521 agatccaatt cacttcgctg ttccacgtag gctatttttt tacggactga gtttaccggc
    26581 tgtccagaaa aggtgacttt accagtagta gctggtatca actctagcaa agatttcata
    26641 aatgttgatt ttcctgcacc gtttggtccg ataataccgg taattttttg tggatttatc
    26701 gtcaagttga tagttttcaa aacagttttc ccttgataag cggctgaaag gtcttgaatt
    26761 acaatggccg tacgttccaa atcttacact cctttttagg tttacctaac tttttattta
    26821 aatatagttt aactaaaatg gaaagcattt tcaagtagaa tgatgaaaaa gtttttttcg
    26881 aattttcctc gcattttatg aaaattttct gtagaatcac atcaagagtt caataaggct
    26941 aacctaataa tgaaaaacat gtgttgaaac gtttgattat tttttcttgt tgactcaaca
    27001 acgaaaggag tttttgtatg gaagaagaaa agttaactcg aagtcttagt gcccgtcata
    27061 tccaaatgat cgcactaggt ggaacgatcg gtgtcggtct gtttatgggt gcctcctcaa
    27121 ccatacgttg gacagggccc tcagtgatgg gagcctatgc gattgcagga ttctttttgt
    27181 atttgattat gcgtgcttta ggcgaaatgc tttacgttga tccttcgact ggttcttttg
    27241 caaattacgc gagcgagtac atccatcctg tggctggcta cttgaccgct tggagtaata
    27301 tttttcaata tattgtcgta ggaataagtg aagtgattgc tgtaggatct tatatgaatt
    27361 attggtggcc tgatttgccg gcaattattc ccggaatcat tgtcgtcttg tttcttatgc
    27421 tggcaaatct tatttctgtc aaggcgtttg gcgaattaga attttggttt tcgatcatca
    27481 aagtcataac gatcattttg atgatcattg caggtcttgg ggtaatctta tttggatttg
    27541 gtaatcatgg tcaggcagta gggatttcaa atctttggaa aaatggtgga ttcttcactg
    27601 gaggcgtcaa aggatttttc tttgcattat cgatcgttgt tgcttcctat caaggaatcg
    27661 aactgatcgg aatgactgct ggtgaagcag agaatcctaa aaagacgatc attgaagctg
    27721 tccagtccac tatcggtcga atcttgattt tttatattgg tgctattttt atcattgtga
    27781 gtatctatcc gtggaatcaa ttgagtgaga ttggttcacc ttttgtacaa actttttcta
    27841 aagtcggcat tacatttgct gcaggactga ttaattttgt cgtgattaca gcggcattat
    27901 caggttgcaa ttcagggatt ttcagcgcaa gtcgtatggt ctatacactt gccataaatg
    27961 gaaagatgtc taaaaaattt ctgaaactat ctcgtcacgg tgcgcctttt tatcctgtcg
    28021 tagcaatctc aggtggaatc ttaattggtc tgatcttaaa ttatcttcta ccaatgttca
    28081 tcaaccagtc agaaaatatt ttcgttttcg tatacagctc aagtattttg cctggtatgg
    28141 ttccttgggt agtgattttg atcagcgaga ttcgcttcaa aaagaagcac gcagataaaa
    28201 tgcatgatca tccttttaaa atgccactat ctccttatac gaattatgtg acacttgctt
    28261 ttttagctat cgtattgatt ttcatgttta tcaatcctga aacgagaatc tcattgatta
    28321 ttggactcgt tttcttgctt tacatgacga tccattactt tgtacgcgaa aaaagaaccg
    28381 gaaaataaaa aaagaacgaa gcttcacctt agtggaagct tcgttctttt ttattgcttt
    28441 tatcaattca attttagcgt ctcaccggga gtcaggaaat aattctccat gctcatccca
    28501 ttcagcgaca agatcgtttc tactggtacg ccagttcgtt cggctatttg atttggacct
    28561 tctccttcca aaactacggt tgtcgcagcc tgtgaagtcg cgctgttggt attagtttca
    28621 gaggaatctg ttgtgtcttg tgttgttcga gcttgcattt cagaagcttc taccgactct
    28681 gctgtctcag aatcagaaga tgttgtgtct tgtgtgcttg ttgactctgc ttgaagagag
    28741 gcgctagtct gcaaataaat atcggaaatc ttagcgacat gattcgtata attagccgat
    28801 aattgattga tcaaagtatc taagtctaca ccgtctttat tttctgctgc ctgatacgct
    28861 gcacgtaatt ttctgatccc ttcgtcggag attgcttgaa gctcacgtgc tttttggtta
    28921 gcaactgctg ataaaccagc tattccctct tgatttccct gaatttctgt ctggtattct
    28981 tcaatcaatg caggcgtctt ttcttcgatc tttttcgaat aatcatttac gattgcttga
    29041 agttgctctg gcaaaccatt tgctgttttt tcttcagaag tttgtgtctc ttttgtttta
    29101 gttgatgact cacttgtttg tttcgtctct gttttctttg tcgttgtttc cgttatggtc
    29161 gtacttttcg cttctgacga attttttcca tgaaaatata gacccgcaac tcctcctgct
    29221 atgatcaaaa acacggcaac tgctgcccca atcatgatca tccgcttacg agctgcctgt
    29281 ttttgctgtc ttcttcgggt catccgaaca ttttctcccc actcattttc atcatacatt
    29341 tttttcacca ccaattttta tgtataatag cgttatcaaa cgcttcatat tcttattgta
    29401 gcaaataatt gtcgctgtgc acatttttat ctttgttatt tataagaaaa tttcaccagt
    29461 tgagatgatt ccaagattgt ccgtcgattt ctccttgcag ctgcattgtt cgttcgtcta
    29521 tctcagccat cagtttcttt atttcatata agagcgcacg gtcttgatat tctgattttt
    29581 cgcttaattc atctaattgt tggatcagcc aatcatttgt cataatgaag ttcctttcat
    29641 ttcttgcagt gtaaaggtca agtcttcgat ctgctctttt gcctcagtca gtgcttctac
    29701 gatatatgct tgtttttcag attcttcttc ctgcattttc tgattttcct gtactctttg
    29761 aataaaccag tcaatccgct gagtcagcga tggtttgcct tccaatgaga gatactgctg
    29821 ataagcaatt agcttctccc aacgtttttc ctgggataaa tacataaatt gtgctaaaac
    29881 gaatggcgga agataggtca tatggaattt atttgcgatt cgctgatacg gcctcaaaaa
    29941 ttcggaaatc gtatattctt cttttcctcc agcttggtat tctttttccg ccacacctgt
    30001 tgtcaatacg attcctagtt ctttcccttt taatacatgt gctgctcgtt ccaagacatt
    30061 atcttgccaa atttttaaat gagcaggaga actataccag taaaacggaa actggaaaat
    30121 gatccgatca tgctgggcca agagctgtag ttcagtctct atatctattt ttccgtctgg
    30181 ataacttgat tccaaatgat gccaagtagc tggtaaacca gcagaagctt ctttgaaaaa
    30241 ttgctgattt aaagattctt cgatcgttgg atggctaatg atgataagtg tacgcatccc
    30301 ttttcctcct ttttagtctt cgctttacag tgtagcataa ccgccacaag tttcttttgc
    30361 cgatgcttgt cattttaacc agactaatca ggttgtccaa gaaactgcgg tttgtttttc
    30421 caactgtttt ttcaaggtat ccaaagcaat attcttaaaa ttttcgtttt tcatacgttt
    30481 acgatagttc gtagccgttt ctccggtact ctttttgaac attcggctaa atacgactag
    30541 actattgaac cctacttgat aggcaatact ttccacggat tcatccgtca gagaaagaag
    30601 aaacgcccct cgattgatcc gtaccccgat caaatattcc ttgatactgg tgcccatatg
    30661 atttttgaat actcgcgaca aatggctccg attgaccgct aaatgctggg cgatttcctc
    30721 aacagacaat ttttcagcat aatgtgcctc gatgtatttg actgtttcaa cagctaaaga
    30781 ggaatgaacc ttttgtacac ctccgctgac ctttccgcca tcttttaaaa ggactgataa
    30841 aaaacggtag gttaatgctg ttaactgtaa ttcattttcc aaggtttctt ccgtatcttt
    30901 catgcattct aaaataatgt cgatatattt ttgtatgtca gaagagacca tcgtgtattg
    30961 gtcttctctg aaaagcgact gccgaatgat ttcttctgca gcactcccac caaatgaaag
    31021 ccagcaatac atccacggat cttctccatc tgataagtaa aacgtcgagt ctcctggacg
    31081 aatcaagaac agatcacctt ttttcaattg gaattgttga tttttcacat gataagatcc
    31141 tttgccttcc atcacgacat gcaggatgta atcattgcga atagcaggac caaaagaatg
    31201 aaacggcatc gttttagaga aaccacaaaa atcaaaatac aattcttttt ctacttgttg
    31261 atgttccttt tttaaaaaaa tcgattgctc cacgtctatc cctccttact cctttagtat
    31321 aatgcaacaa aaagttaaat aaaagtcaca gaaatatatt aaaaaggaag cgatttcttg
    31381 ttaagtttaa gtcattaaaa gatctttgtt attcgttgta accggtttac ttagtattat
    31441 atattgaaca ggagaggaat acagattatg aaaagcaaaa tgatccaacg tgtgtcctac
    31501 gctttaggcg cttttggaca cgacacattc tatgttacat taagcactta ttttatggta
    31561 ttcgtgacaa gccagatgtt cgcaggaaca gataaggcaa cgaatgcaaa aatgattgct
    31621 acagttacaa gcttagttgt aggtatccgc ttagttgaaa ttatttttga tcctttgatt
    31681 ggtggcatca tcgataatac tcgtacaaaa tacggtaaat tcaaaccatg gttagttatc
    31741 ggcggcgttg ttagttccgt actcttggta gcaatcttta ccaatttctt tggcttagct
    31801 actcataata cgactttatt tatcatatta tttgcaatcg ttttcatctt attggatagt
    31861 ttttattcat ttaaggatat cgctttttgg tcaatgattc cagctttgag tacggaaaca
    31921 aaggaacgtg aaaaatttgc tacgtttgct cgtttcggct cttctctagg tgcaaatggt
    31981 actactctag tcgttgtccc tatcgttact ttctttacct atcttgttac tcataaacat
    32041 attgaaggcg cttcaggctg gttctggttc ggtgtgattg ctgctgttat ttcaggcggt
    32101 actgcgatta tcactgcctt gggcacaaaa gaagtcgata ctgcgatccg tcagcaaaat
    32161 gaaaaagctg ggatcaaaga tgtgttcaaa gcagttgctc aaaatgatca gttgatgtgg
    32221 cttgcccttg cttatatcgc ttatgcgatt gccaatgtag caacaactgc cgtattattc
    32281 tacttcttca aatatgtact tggccaacca actgaatttt ggatcgttgg tctagttgct
    32341 gccttacttg gtttagtagc tgttccacta ttcccaatgc ttacacgcgt catctctcgt
    32401 cgctacgttt accttggagg gatcgcaatg atgatttctt cttacttttt ctttacgatc
    32461 gcaggttcaa gtttgccaat cgttatcatc gggctagtat tgttctactt ccctcaacaa
    32521 ttgattttct tatccgcttt gatgacgatc acagactctg ttgaatatgg tcaatggaaa
    32581 aatggtatcc gtaacgaagc tgttactcta tcaattcgcc ctttactaga taaaatcgct
    32641 ggtgctttgt ctaacgggat cgtagggttt gtcgctatcg cttctgggat gactggtaat
    32701 gctactgctg ctgatatcac tgctcatggc gtaacgactt tcaaagctta tgcattctat
    32761 gctcctgctg ctttgatgat tttctccgct attatttttg cttggaagat tacattgaca
    32821 gagaaaaaac atgcacaaat cgttgagaaa ttggaaaaca aattggctcc agctgataca
    32881 atggaagatg aacttcacga tgcagtagtt ccttcccatt aagaaaggat cttgaaaatg
    32941 aagattacag aaaaagattt tggccaaggt tatcacttga taaccttgga gaacaaaaac
    33001 aagctagcac tttctatctc tgatttaggt gctagaatcg tcagtttaaa atcaaatgat
    33061 cgagaattag ttttgggatt tgacaccgct gaagaatata tcgaaaaaga tccgtatatc
    33121 ggtgcttcta tcggtcgcac cgcagggaga atcgaaaatg gccgcttttc tctcaatgga
    33181 aaaacttacc aattagccac agatccaaaa actggacata atctgcatgg tggtgctcct
    33241 ggatttgaat taaaaaaatg gtcttatgtc attttgaatg gcgaaaatga agcttctgtc
    33301 atttttacta ctacaagtcc cgacggagaa catggttttc caggtacaat ggatgtggaa
    33361 atccgctata ctttgacaaa agataatatc tggcgagtga cctctcgcgg caccagtgac
    33421 caagatactt tattcaatcc gacaaatcat gtttacttca acttgacggg agatgcttct
    33481 cagtcaatcg atcaacatga gctttggctc aatagcgaag cttatgctcc tttgcgaaca
    33541 gatagtattc ctataggggt aaaagaaaat gctgcaggaa gtgctttcga ttttcaaata
    33601 cctaaaaaat tagcgtccgt ttttgctagt gatttggatc aaaaaaatct tgttgacgga
    33661 atcgatcatc catttttctt aaaagaaacc ggcttgggta aagaagccgc tcgcttgact
    33721 agccccgata aaagaatcca agtagatatt gctacagatg cttctagtgt ggttattttc
    33781 actgcaaatt tcggcacaga aacaccagaa atgcgcaacc gaaaactggc acatcacggt
    33841 ggcatcacat ttgagactca aacagctcca ggtgcagagc gcttctcagc atttggttcg
    33901 attcatttaa aagccggatc agtatttgaa acagtgacag aattcaaaat caaaacaaga
    33961 aaggaataac tcatcatgga aatcaaaaga agcttaaaca caaaatttgc cgaaacattc
    34021 ggacctaaaa aaactacaca atacttctca ccaggacgca tcaatttgat tggtgaacac
    34081 acagattaca atggaggcca tgtcttcccc gcttccatca cttatggaac gcaaggtgta
    34141 gcagcacctc gagacgataa taaaatatta gtttattcca caaactttga cgatatcggt
    34201 gtcattagtt ttactttaga tgagctagaa tatgataaaa aagcaaactg ggcaaattac
    34261 gtaaaaggaa tggtccttaa attaaaagaa gctggacact caatcgatca tgggtttgag
    34321 ttattagtgg aaggaacaat ccctaatggt gcaggacttt ccagtagcgc ttcattagaa
    34381 ttattagtag gtgttgtatt agaagatctg tttgatttaa aaacagatcg cttggaacta
    34441 gtccaaacag gtaaaaaagt agaaaatgaa ttcatcggtg tcaattcagg tatcatggat
    34501 cagtttgcca tcggcttcgg tgagctagat catgcaatct tattagatac aaatacgctg
    34561 aaatacgaaa tggttccagt gaaactagat ggttatgcaa tcgtcatcat gaatacgaat
    34621 aagcggcggg aattggcaga ttcaaaatac aatgaacgcc gtagcgaatg cgaagaagcc
    34681 ttggcacgtt tgcaaaaaac tttgcctatc tcttctttag gagacttaga tgaagaagaa
    34741 tttgaatcaa ctattgacca aatcggcgat gatacattga tacgcagagc tcgccatgcc
    34801 gtttctgaaa atcagcggac tttgaaggca aaagctgaat tagaagctgg gaacttagaa
    34861 gcatttggtc aactgttaaa tgattctcac cactctcttc gctatgatta tgaagtaact
    34921 gggatcgaat tagatacact agtagatgct gctcaaaaac aagaaggtgt cttaggtgca
    34981 cgaatgacag gagctggatt tggtggctgt gcgattgctc ttgtcaaaga agaaaatata
    35041 cctgccttca aaaacaatgt ctatgatgaa tacatgaaag ttgtcggcta tgctccggaa
    35101 ttttatgttg cacacattgg aaatgggaca acaaagatcg atccagaagc tgttcatgtt
    35161 tgataaaaaa atcaacgatc tcagctaaaa acaaatagat aaaaataacc tctcagcaat
    35221 ttccaaatgt gagccttttg ctcgtatttg aaaattgctg ttttttattg acacggaaag
    35281 agaacgtgtg ttctaattgt gttgaagagg tgattgttat gtgggcgaat caaaatccgg
    35341 tatttgttta tgaaaaagaa ccttcaagag atattttatg tattgactgc aaatcttttt
    35401 acggtgcgaa acgttcctaa ctgaaaaggt taggcacaca agattttctt gtgtagaact
    35461 aatgatttga ggagtgaaat gacggtgtaa cgacctgaag cgctccctct gatactccga
    35521 ttggcaatac cttaagttag aataggaatt gtcaaaagct cggtaaagtc ggctgagagt
    35581 taccgcagtt gcattatgca atcgaaagct gttcagcggt gaatggtgta acctataggc
    35641 cgggagtcca gaaattactc atggtgagaa tgtgcagctg cactgacgaa ctcgcgaatg
    35701 tacgaatcta taagcttggg gtacagaaat gtatcttacc cgcacaaata ttactgtgac
    35761 aaagggtgta gcttgcggtt aagtaagaat cgtagatatg aacaaccgtg caatgtagta
    35821 ggcattggaa agttacaggt tcagagtgag cgcctaaaag taaatgcagg gataaaatca
    35881 ttggaacgtt gaaagctagt gtcgtggagg actaacttcc tttgaaacgg ttgagacgaa
    35941 gaataataag ctcatttaca ctagtgagag tagtggcaca gtacctatga agcagtgata
    36001 ataagctgtg gagggatagc cacaagtcaa tttgctttac taacagttat gatacaatcc
    36061 atagaatcga gtatgacaaa ataaacgccg acgtccgaaa ggaggcggtg ctatggaaaa
    36121 cgtatcagca tcacattcaa ttcgccatat ggaatattat ggtcttattg atagctttga
    36181 ttctctttac aaagagagta gcgagaacaa aattttcagt aaccttatgg aaattgtcac
    36241 ttctcctaat aacattctat tggcatttcg gaatgttaaa ggaaattctg gtagtacttc
    36301 cccaggcgtc gacaaaaaga atattgatga tttaaaagca ataccgaata tcgagtttat
    36361 aaaaactgtt caaacaaaat tttcagaata taaaccgcaa ccagttaaac gagtagatat
    36421 tcctaagcca aatgggaaaa ctagaccact aggtatacca acaatatggg atagaatcat
    36481 acaacagtgt ctactacaag ttttagaacc gatcatggaa gcaaagtttc atgataagaa
    36541 ctatggtttc cgacctaacc ggtcggcaca tcatgcattc gctcaagcag tacgaatggc
    36601 gcaactttca aaactaactt ttgtagtaga catagacata gaaggattct ttgataacgt
    36661 aaaccattca aaacttatta aacagttttg gacattaggg gtacgtgata aatggcttct
    36721 aggtgttatc cgagcaatgc ttaaagcacc tattattcat agggatggac gcattgaaca
    36781 tccaaagaaa ggaaccccgc aaggcggtgt tctctctcca cttcttgcca atgttgtttt
    36841 gaatgaactg gactggtgga tatcttctca atgggaaaca cacccgacta ggaaaaacta
    36901 cgattgttat catcaaacaa gaaagcaatg gattaagagc aacaaatatc gagcactgcg
    36961 tgcttcgaaa ctaaaagaga tttatattgt tagatacgca gatgacttca aaatcttctg
    37021 tagaaaacga agtgacgcag acaaaatctt tctagccact aaattatggt taaaagaccg
    37081 actgaaactt gatataagtg ctgaaaaatc aaaggtagtg aatctaaaga aacagaaatc
    37141 tgattttctc ggattcacaa tgaaactggt acgcaaaaga aaaagctttg tgattgaaac
    37201 gcacatgtgc gccaaagcca tgagtgcagc atctaataag ttagcaaaac aaattaaggt
    37261 gattcaacat tcacctaccc aagttgaact tcaaaaacag ttaagtattt ataactcaat
    37321 ggtagtaggt atccatcaat attataaaaa ggcaacccac atcagtgtgg actgcccaag
    37381 aataaatcaa cgcctaatga ttatcatcaa aaatcgacta gatattaaga gaaagggtcc
    37441 tccaccgagt gattttatta aaaaaaatta cgctcggtca aagcagttga ggtggcttaa
    37501 tggtgttcct atgcttcctt ttggattcat aaaacatagc cacacctccc tgcccaagat
    37561 aggaacctgt aaatacacgc ccgaaggtcg tgtgctgata cacaggtatc ttactttccc
    37621 aatcgatatt atcaaccaac tcatgaacat gtctaatcct aatgaaagca ttgagtttag
    37681 agacaatcgt gtatccaagt actcttccca agtcggccgt tgccgagtaa cgaaagaagt
    37741 cttagagcta gcagacatat actgccaccg tattgtccct aaaaatctag gtgggaaaga
    37801 caattatcaa aatctggtca ttgtccaccg gaacattcac tcacttattc atgaagagga
    37861 taaaacaaga gcatcacttc tcatacaaaa catgagagtt acaagtgctc aacttgagat
    37921 aatcaaccag tttcgcaaaa aagctaagaa tcgtgaattg tcgctgaatc tataactgta
    37981 tgatactgtt agtaaacttt gatggaacgc cgtatgcggt gaaagtcgca cgtacggtgt
    38041 ggagcggggg aaaatctgga gattgcatca aaggattacc tatcgctatc ctccgtagag
    38101 tgcgttgaaa aggatcttga tccccttaca actaaattag tagtcatgtc ctatccgtcc
    38161 gattcgacag aaacacgggg tagcggatta atcttggctt ccagtcctgc agcaaaaaaa
    38221 gcttacggca tcaccaatat cagccgtgcc agagatcttc ccttccccta tccaagtgat
    38281 ttatatattg ttgccccaag gatggcctat tatatggaaa agaacagaga aatcaattct
    38341 atctataaaa aatatgcaga cgaagcgaac catcatgtct attccgtcga tgaaagcttc
    38401 cttgatgtaa caaatagcat ggcactcttt ggtaaaacaa atgcgtacga catggctaaa
    38461 ctgatccata aagatgtgtt tgagcagacc ggaatctaca cgactatagg aattggcgat
    38521 aacccgctac ttgctaaact agccttagac aatggctcaa aagacggaaa gcaaatgttt
    38581 gctgaatggc gttatgaaga tgtaccagaa aagttatgga aaatctcaga tatcactgac
    38641 ttttggggaa tcggcaaacg aacagcaaaa cgtctgaaac aaatgggtat acattctgtt
    38701 tatgatttag ctcacgcgga ttattatcac ttgaaaagca agctaggggt catcggtact
    38761 cagctttatg cccatgcttg gggcatcgat cgaagttttt tgggacaaga atatacacca
    38821 aaatcaaaaa gtatcggaaa tagtcaaatc ctagatagag attatacaag acgagaagaa
    38881 atcgagatcg ttatcaaaga aatggccgac caagtcggca ctcgcttgag acgatctgca
    38941 gcaaaaacac aagtagtcag cttatgggta ggatactctt taggctatct tgatccaaat
    39001 ggcaagaccg ggtttcacca gcaaatgaaa atcgaagcga caaatgctag cagagatcta
    39061 gcagatgctt tattgaccat tttccaccag cattaccact accaggatat tcggcgtgta
    39121 ggcgtgaact gttccgacct cgtatacgcg acaggtttac agcttaacct ttttgaagat
    39181 cctgaaaagc agataaatga agcgaaagtt gattttgttg tcgatacgat tagaaaaaaa
    39241 tacggctttc aatcaatcat ccatgcgcat agtctcttgc aaggaggacg cgccatcgca
    39301 cgtagttctc tcgttggcgg gcatgcaggt ggtatgagtg gattagaagg tggaaaagat
    39361 gagacggaca gcaaaaaaat tcattgacta taacgagtat cgagatcggc catttggatt
    39421 aaaatggggg actgcttttg cgatggaaga actagtcaac ggtatcaaaa aaaatgaaga
    39481 agaagcacgc aaacagcctc ttcctaaaca acaaatgaca ttgcaagaaa tcgatagtat
    39541 actgacagaa gcctttttat ctcgtaaagc agtaatcatt cagctcaatt taaaagatga
    39601 atttggaaga ctcttggatg aggtcgaagg gcacttcatt ggtgaagcct atgaagatta
    39661 ctttatgatt gaccatcagc cgatattgtg ggaagacgta cggtatattg agttaaagga
    39721 aacaaaaaaa tggtttgtga catgagaggt tgtgacagaa gtgatcaact tcaaaaaata
    39781 agaaaggatt tttcgaaaat tgcttcttaa atttttgtgg aattttggct tatttttcga
    39841 agaagcaact tctggaacaa cgtatattag atatcagagg ttgtgaaaaa gtcgcttagt
    39901 tttgagtaac aagccaaggc gctgatttca caacctctgt ctatctatcc atctattcgg
    39961 taagattcat gcatgacgtc ttctttattt agtatgtaga gccctttttc ttctgaccat
    40021 tcaacataaa tcagctgttt tacatctgca tagccttctt tcttcaagtt ctccataagc
    40081 catgcttcag tcaattgatt ggactgaagc actttatgct gaatttgccc ttcatctaca
    40141 agcaggatcg ataaagcttt gtcttcatct gattttttca atacactcat ttgaccggca
    40201 ttctctagga taacatgttt ggcattttca agaaaaaagc attcttgctg tcttaagatt
    40261 gctcgcaact gctccatctc gatatggtta tttgtcaact ctgtcatgtt gatgacgccg
    40321 tctttgatta gaacagatgg ctcgcctttg acccaacgat tgaccttttc atttttttgg
    40381 acgatacgtt cgataccata aatcattact gcccaaagcg caatggcaaa taggacatgc
    40441 cctacatgga cattgtcatc ataggttgat tcttctaaga tcccacctaa aacaagcgta
    40501 tagactaaat caaacggtgt gatttctgac atggatttct tcccaagcaa acgtaccact
    40561 aataataaac cgatcaaccc gaacaccagt ttcattgtaa ttgaaaaaat cattttttct
    40621 ccccctaact atctgttaat taaattatat atgctttctc acgaacacgc atggaatata
    40681 caaggaagaa atgtatcctt ttactaaaaa aaggactgtg acactgtagt gacccccaaa
    40741 agttagactt ttttggagtg gagaaatcca ctcctttttt ttatgctcta aaatgatatt
    40801 tttacacaac cgttacggtt gttttacgaa attggacgag actttgccag tttaatttct
    40861 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
    40921 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
    40981 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
    41041 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
    41101 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
    41161 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
    41221 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
    41281 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
    41341 gatggatccg atttttggct actgctccaa cttttcctcg ataagaattg tagcgacgtg
    41401 atttacgcgt gtatgccgtt acttttattc ctagcttctt gatcaagcgc tgaactttct
    41461 ttttattgat agagaaaccg cggtttctta gttcattggt catccgtaaa cagccataat
    41521 ccttgtgctt ctcccgaatt ttaagcattt ccgcttcaat ctcttgatct ggatttttac
    41581 ggtccaatcg cctttgccat ccaaataatc atgaacgatc tttaatttaa gttcaaaagt
    41641 atatttaacc ataaaaaata ccgacctcca aaagttagat tttttggtct aacttttggg
    41701 ggtcggtaca caaatcgtgt cacagtccct tttttgaaaa taaacggtgt tcaaaagctt
    41761 gcatctgcgg taataagtcc agccaagtta aaaacataag aagctgtttt tacttggctg
    41821 ttcttattac ttgatgcaag gcagcttttt cacaacctct tttcaaatat ttcgttttct
    41881 tattctacaa atggttcttc tcctaacgct tgttgagcgg ctagattcaa catgctccat
    41941 tgtcggtcaa agcctggctg gaagaagaag tcagcttctg ctagttcttc taaagtcagt
    42001 ttgttttgga tcgctagtgc caatacattt ccttgacctg taacatcata ggtagataat
    42061 actgctcctc ctagcaattg atgggtcatt ggatccgaga ataattggat ggacactttt
    42121 ggatttcctt gttcttctgg tacatatttt ggtcgtaacg tatcttcata ataagacact
    42181 cgtacatcta ctcctgcttt tgctgctgta aagctattca atccgcttgc tgcaaaatga
    42241 tagtcaaaga cacttaatgc agaggaacct acgactccgc cgaacggttt gtttggtact
    42301 tcttcaaaaa gatgttttac tacataacgt gcttctctac gtgcaacagt cgctaaagcg
    42361 atcggcattt ttttgcgtgc tgggatagaa taagcaagtg tagcatctcc tactgcatac
    42421 acatctggaa gattcgtttg caagtattca tttgtttgga tccagccacg ttcatctaag
    42481 tcgacgatcc cttttaacca ttctgtattt gccttcacac cggcagcttg aatgactaga
    42541 tctgctggga tttctttttc acttgttttg attgcctcaa cttttccgtt accagtaaaa
    42601 gcttcgattt ttgcatttgt caaaacttca ataccgtttt catttaggtg ttgttctaaa
    42661 atatctgtca tctcagcatc taaataagtg cctaaaggtc tatcgatcac atcaagcaat
    42721 acgacttctt tcccagcttt tcggcttgct tctgctgctt cgatcccaat gtaacccgca
    42781 cctacgacag cgattttttt aatagccgga tcatttaatt tttctttgat tttggttgcc
    42841 caattgtatc cacgcatcaa gtagacattt tctagatctg ctcctggtac tggcagattg
    42901 tttggtttga caccagaact caaaatcaat ttgtcataag gatattcttt tgtttcgtta
    42961 tctgatacgc tagtaaccgt tactgttttt ttatcggcat cgatcgtttt tacttcgtga
    43021 ttatttaaaa tatgaacatt ggattgcgga aagttttctg gtctgaaatt acgtacatca
    43081 tttacatctg ttaccttgtc ttctaaatac agctccatac cacatgacat gaaggaaata
    43141 tagtctcctg cttcaaatag cgtgatatct acattttcac cgtatcgtgt caatagttcc
    43201 aagattgatt gatgccctcc atgagatgca cctacaatga caactttgat tttttccatt
    43261 gatgaaacct ccttgaatat tcttttaaaa tcattctaaa caatttaaac ttaacattac
    43321 attagttatg aatcaaaaga aacgcgttca tttgaactaa atttaaaaaa caatcgttaa
    43381 ttttgcagaa tataccgcaa aattaacgat tgtttttttg ataaaatcta tgaatcactg
    43441 ttctgttaaa aagtctttga ttcgtttgca ggcctcatgt aatttttcca tgctgctagc
    43501 ataagaaatc cggatataac cttctccttc tgggccaaat gcaattcctg ggatacacgc
    43561 aacttttgcc tgttccgcta attctacaca aaactgccaa gagtcagttt gaatggcagc
    43621 tgggagtttg caaaacaagt aaaatgcacc gtttggctgg gtcacttcaa atcctaaagg
    43681 cgccaattgc tggaccagat agtctcttcg tgtttgatat tgctctttca tattctcgct
    43741 atctttcacc ccatttatta gcgcttcagc tgcagctttt tgcgacatcg ttgtagcggc
    43801 agtcaccaga tattgatgga ctttaattag ttcgtcaata agggcttttt gagcaaaaat
    43861 aaagcccact cgccaaccag tcatcgcatg tgacttggat aacccgctta tcacgattgt
    43921 ttgttctgga agataagtag ctatggacat atgcgttcca ctataagtca attcagcata
    43981 tacttcatca cttataacaa ataccggata tttttttaaa acctcagcga ttgctttcaa
    44041 ttgttttgca gacaatgtcg tcccagtagg attgttagga tagtttaaaa tgactgcttt
    44101 gacagctgat ccatattgtt caaatgctcg ttcaaattgt tccggctgac agacaaaccc
    44161 tgtatcagaa gtatctatcg ggatcaattc agcaccagct agttccacta atggctgata
    44221 tcctgaataa gcaggcgctg gaataagaac cttgtctcct tcttccaaaa cagataacaa
    44281 cgcagaggca atcgcttccg ttgcaccaac tgtcgtcaaa acttccgttt gcggatcata
    44341 agttaatcca taacgctgtt gctgaaacat acaagccgct tcccgcagtt cctctaatcc
    44401 tctcattccg gtatagtgag aaaagtcttc ttcaatcgct gctattccgg cttgtttgac
    44461 atgtttagga gttggaaaat ccggttctcc cagggtgagt ttgatcacat ctggtatcga
    44521 cgatatttgc tgatcgaatt gtcgtatttt tgatacttct attctagaaa gcctgggact
    44581 aaatcgattg gataaattca tcattatata ctcgctcctc ttttgatctg ctatcgattt
    44641 ttacaagaag attttctgta aaaagaatcg ttttgtacca ttctacacca ttttctaaaa
    44701 catccatatc aaaatcgaac gtcggatcat gtaaagcagg ggtatcaccg acacctaaaa
    44761 agaaaaatac acatggatat tgttgcgtat atatgccaaa atcttcggct tgaagaactg
    44821 gagcatctaa ttcatgtagt ttgtttgaat ctaacagtgc tgcatataag cctctatggt
    44881 tgattacagc tggatagccg tcattatagt gaaaagaaat agtagctgta gagtgaaact
    44941 gttctgctaa atggtctaat cccctcttca aataattttg catatctgaa ctgtaagaac
    45001 ggatacttcc agatacaata acttctccag ctaaaacatt tcggatcgtt ccaccttgga
    45061 tttggccaaa tttcattaga tgattccact ctgccggtaa ttgccggtca aaatcataaa
    45121 cattcttcaa aaatcgtaca gctgcctcca gactatcgat tcctttttca ctagaagcaa
    45181 tatgtgcaga ctggccttta atgataatgt ctgtttcact gctttgtgcc atcaaaggtc
    45241 ctggtcgaga gaaaacttct cccttagcta gtccaggcca tagatgaaag ccaaatattg
    45301 cttgtacttc atatttatcc aacaatcctg actgaataac gctttgtgcg ccaccggaaa
    45361 tttcttctga tggctgatag atcagtacta cattataaat aagatcctca atgtgtttag
    45421 ttataaagtc agtcaaccct aaaagcatcg ccatatgtcc gtcatgacca catgcatgca
    45481 tatacccttc atgcttagaa gcaaaagaga gattcgtttc ttctttgact ggcagtgcat
    45541 cgatatctgt tcgaaaagca atcgtttctt cttgctgatt atcaaaataa aggagtagtc
    45601 ctgtttcgcc gatttcatgg ataacggccc cgctgttttt tacttgttca tataaatatt
    45661 tttttgtctt gaattcatga aatccgattt caggaatttg atggagtgcc attcgatatt
    45721 ctttcagcat ccgtattcac catcccttca tagataccct tcactactgt ttcatattgg
    45781 ttattcggta caccgatgat cagattcaac tcctgtgctc cttgtgataa gatcgatgtg
    45841 cgaatttcta atttgttcaa tatcgataac acttttccag ataaaccgat caattcttta
    45901 tgtggtccgc caacgacaga gatcaaagct aagtcttcaa tcacgacgat ttcttccacg
    45961 ccaagtgttt cttttaattc tttcgtgatg agaaataatt tatcggcaat cgcttctgct
    46021 gagacgatca ctccgatatt gtcgatccct gaaggaatat gttcgattga tatctcatgt
    46081 ttagcaaaaa tgctcattgc tttccagata aacccgattt catcggacat atgtcgttta
    46141 aataaagtga tggaaagaaa atccttgcgt ccagctattc ctgtcagtcc attttccttt
    46201 tctatttcgt gattcgatat ttttgtccct tgagcgaaag gatcattggt attttttatt
    46261 tggatgggga tatcagcctc ttgaactggg aaaacagctg cttcatgaag aacgttagcc
    46321 cccatataag ccatctctct cagttctcta aaagagattt cctcgatgat tttaggatga
    46381 tcgatgattc gcggatcagc catcatgatt cctgaaacat ccgtccaatt ctcataactt
    46441 tccgcttgca acatcttcgc cagtatcgcg ccggtaatgt cgcttccccc acggcccaat
    46501 aatttttctt ttcctgcagg gttcgccccg taaaaccctg gaacaaccat tttcgaatat
    46561 cttttaaatg cttttgtgat ttcctgtgct gttttttcct gatcgatttt cccatcatag
    46621 tcaaagaaaa tcaggtcttt tgcgtcaata aactggtaac caagatactc agccatcagt
    46681 tgagcagtca gatattcacc tctacttact aaataatctt cagttatctt ttcgtcttcc
    46741 agttgtttct gtatgcgtgc tagttcatct tcaataggta actgcagggc aagaacatct
    46801 cttacttgaa tgaaacgatc acaaatcctt ttccaaaggg gtgtccaatc aacatgatgc
    46861 tgaaggtaag cataaatcaa ataaagtaag tctgttactt tgtcatcatc tgacgtacgt
    46921 ttgcctaaag cagaaacaac gatcacttgg cgattgggat ctgaaagaac aattgtacgg
    46981 acttttttga attgctcttc atgagacatc gatgttccgc cgaatttcgc tactttcagc
    47041 gtattactca tcttgccacc tccgctattt tctgcattaa agctgcagca atctgtacgg
    47101 cattcgcagc ggctcctttg cgtatgttat cggcagtcgt atagaacaac aatccgttct
    47161 ctaaagaagt gtcttttctg atcctcccaa cataaaccat atctgttcct ctagcaagaa
    47221 tgctcgtcgg atatttatgt gctgctagat catcttctaa ttgaatccct ggaaactggc
    47281 tgagacactc tctaatttct tccgtcgtaa actctttttg cagttgaact gccacagaga
    47341 ctccatgtcc attttcgatt ggcacacgta cgcaggttgc tgatactggc aaagcaggct
    47401 gatgcagaat cttacgggtc tcatttatca ttttctgttc ttcttttgta tacccatttt
    47461 ccaaaggctg atcgatttcc ggaatcaccg tttggctaat attataagga tacaaaactg
    47521 gttcctcgtc attttgcgta cgatgaagat cttcaatgcc tttttgcccg gaaccagaaa
    47581 ctgcttgata ggtcgaataa ttgactcgct ggataccaaa ggcttcttgt aaagctttaa
    47641 gcggaagtac cgcttgaatg gttgaacaat ttggatttgc aatcagccga ttcaatgtat
    47701 agtcttccag attgacctct ggaacgatta atggaatatc cgaatcttcc cgccatgctg
    47761 aggaattatc tatgacaaat agtccctgac ttcgtgcgat tggcgcaaac tctttggata
    47821 cagaagcacc tgcagaaaat agcgctaaat catatccttc aaatgaagtt tctgtcaatt
    47881 cctgtacagt gtgtttcttt ttcttgaata cacaaacttt accggctgaa cgttttgaag
    47941 ctaataattt caatcgtcct actggaaaat catattcttc taacactttg agcatcgttt
    48001 ggccgactaa tccggttgcc cccacaatac aggtatctat ttcgcgcatt tttctccatc
    48061 tcctctataa ttcgcgtaac gcagcaatca atgctgtatt ttcttttgtc tgatcatcac
    48121 ttatttttaa tacacgtgca ggtattccac cgacaacagt tcctgctgcc acatcttcta
    48181 aaaccactgc tcctgctgcc acgactgcat cttttccaat atggacacct tcaacaatca
    48241 ctgcattcgc acctaccagt acgccgtctt ctacgataac cggtttggcc gatgctggtt
    48301 cgatcacacc tgctaagaca gctcctgcac caatatggca gtttttgccc actgtcgctc
    48361 gtccacctaa gacagcaccc atatcaatca tcgtgttttc accgattact gcaccaatat
    48421 tgataatcgc tcccatcatg atcacggcat tgttgccgat tgacacttga tctctgataa
    48481 tagcacctgg ttcgatacga gcattaattt ttttaatatc tagcaaagga actgcgctgt
    48541 atcttgcagc agtttcgatt tcgatttcaa tgattttttc tgattcagct tctaaaaccg
    48601 gagcaatcgt ctcatagtca ccaaaaacaa cgaagctgct tccttcacca aaaactttac
    48661 tttctttaaa ttcgattggc tcggttacat tcagatagac tttcacaggc gtctttttag
    48721 atgccgtttg aatgtagcgg atgatttctt gagcttccac gttttttaca cccctttgtc
    48781 cattaataaa tcttctaatt tgtaataacc tggtgactga tctttcaacc agtccgctgc
    48841 ttctactgcg cctgcagcaa agattcgatt agaaaaagat tcatgtttga tcgtaaatat
    48901 ttcatcagta gcagcaaaca atacatcatg ttcaccaggt aaagaacctg cacgaatact
    48961 gtgtacacca atttggtttt cttctctttt tttcccttgc cagttgtata cgggctgcag
    49021 cttttgcact tcttggattg tttgaagcag catatttgca gtaccagatg gtgcatcttt
    49081 tttacgacta tgatgttttt caatcagttc gatctgccag ccttgcaaca ttgcagctgc
    49141 ttgcttgatt agttgattca tcaccatgat gccgaacgaa aaattagcac tatacatcac
    49201 aggtacatgt ttggcatgtt cttttatttc ttggaactgt gattgtgtat aacctgtcgt
    49261 gccaatgact aacggaagtt gataagacaa gctatacgaa aggattttct ctaaattatc
    49321 tggatgagaa aaatcaataa gcagttctgg cagttccgta aaagcaagcg tagttgcttc
    49381 tttaggtgcc gtccgtaaaa gaaggaccgt atctcctctt tcttgtgcaa cttcttcgac
    49441 tctatttccc atctgtccac tgccaatcag tccgattttc atttttcaac cgtcctttct
    49501 tttaacaaaa gctgagctaa ttgtttcttt ttctcttttg aaagagaaac taaaggcagg
    49561 cgtagaggtc cggaaggtaa gtctaataat gacatggctg ctttgacagg aataggattg
    49621 gtctcactga acaaggcatg gatcagttca agtgcattta attgcttttc ttttgcttgc
    49681 tgccatcttc cgtcctgcgt atcttttact aattcatgga ctattttagg ttggatattc
    49741 gcccatacac ttattacacc gcttcctcct acactcatta ctggtaggat caaatcatca
    49801 tttccactgt aaaggaagaa ttcttctcca atcaaccgag cggcatccat cacataagcc
    49861 atatctcctg aggcttcttt caaaccaatg atattaggat gttctgctaa atttactaat
    49921 acatggattg gaatcgacat gcctgttcta gaaggaacat tatacaaaat aagcggaatc
    49981 ggtgaggctt ctgcaattgc tgtaaaatga gcagctagtc ctgcatcact tgttttgttg
    50041 tagtaagggg tgatgaccaa aagtgcgtct gcccccaaag aagcaaaatg cttcgctttt
    50101 tcaatcgttt ctttcgtatt attcgttcca gctcctgcaa tcaccggcac acggccagcc
    50161 actttcttta ctgtcagttg aaggatctgc tcctcctcag attgtgtgag cgtagaagat
    50221 tctcctgttg tacctaaaac taataatccg tctgtttgtt catctaaatg gaattggatc
    50281 aatttttcca aaccagcata atctactgat ccctcttcat tcatcggcgt gatcagcgcc
    50341 acgatcgaac cttttatcat cttcattcct ccaatattct tgtccattca tgaactgctg
    50401 ggccagccat ttgtatcgca tcctcaccag agatcatcaa gtctccttgt tccaagtgaa
    50461 caactacctg atctgctgaa attttcccag tttccttagc aaccacataa gaggcacagc
    50521 aacctgtacc gcaagcaagt gtccaaccta ctcctctttc ataggtacgg acgatcaatt
    50581 cttgttcatt gactacttct acaaagttga cattggtttt ttctttgaac aaaggatgat
    50641 gacagatcag ttcacctctt tttctccaga cttcctcacg cgcattttca acaaaaacaa
    50701 cggtatgaat cgttcctaaa aataaactag tgatcgttac tttttcacca ttgatctcta
    50761 tttcctggtt ttttattgga taagtttgat tagctttgat tttttccgga gaatcatctg
    50821 gcactcccat atctacgctg caataaaaag gtgagggatc caacaccgta atttttcttg
    50881 tgcctgctaa tgtctctacg ttgaattcct gttcattcat catgttctga tcatttacgt
    50941 atcgagcaaa acagcgaatg ccatttccgc acatcggcgc gcggctgcca tctttgttgt
    51001 aatagatcat ttccaacgga tcgattttta cggcgatcaa tccgtctgta tcatattttt
    51061 cttttgtgca taaagaagcg gctaattgac tataatctgt gtcttctgcg taatctaata
    51121 agataaaatc atttccgcag ccattatatt tatgaaggat cataggaaac ttcccccctt
    51181 agtagatcag aaaatgcttg tctgcgaaca atcagtcttg attggccatt attgacaaaa
    51241 acaactgctg gtcgtgtcgc tcgattgtag ttgctgctca tcgagtatcc ataagctccc
    51301 gtggaataaa cagctaaaag atcacccgat tctgctttcg gcaaataagc ttctttaatt
    51361 accacatcgc ctgattcaca catttttcct gcaatcgtca ctttctctgt tttttcttcc
    51421 gacagttttg ctgctaaatc acaatcgtat tctgcctgat acagagctgg acggatatta
    51481 tctgtcatcc cgccatctac aaagtaatat tttttatgtg gtgtcttttt gatgaaacca
    51541 atcgtgtata gtgttgtacc agcttctcca acaatacttc tacccggttc aatcagtaat
    51601 tgacgaatgg tcagttttcg tttttccaaa gcttcttccg tatattcaat cagttttttt
    51661 agtgcctctt cgactgggat tggctgatca ttttgtgtat aacgaatccc aaaccctccg
    51721 ccaagattca aggaaagagg ttggtcaaaa tcggttaagt aattcgtcaa tttgtcgatt
    51781 tcagctaacc aagcagtaac atcaaaaatt tgtgacccga tatgagcatg aaatccttct
    51841 aactctagat agcttctttc ttttatcaac tgaagggctt gttggcactc tttactttca
    51901 tagctcatgc cgaattttga atcaatatgc gcagtgacga tatattcatg agtatgtgct
    51961 tctactccga cattcaaccg aagcatgata cagatttttt ttaaatagcg ttggcttaat
    52021 tctgctaata attcaacttc catcaaatta tcggcaacaa tatgcaacaa atcattttca
    52081 agtgcataga tcagttcctc tggcgtcttg ttgttaccat ggaagtagat agtatctcta
    52141 gggaaatcag cttgcaaagc ggtatagatt tccccaccac tgacaacatc tagcccgaat
    52201 ccatattcac gaactaaatg cagcatctca atcgtttgga atgctttaga ggcgtaaagt
    52261 acttttgtat caaaacgttt cgatacaaag cctcgcttga atgacagcat cgtttgtctc
    52321 atcttttctt catcatacac atacagaggt gtcttatact tttctgccaa tgtgcttgct
    52381 gtgactccgc caattatcaa ttctgtcatt ttttcattcc tcttttcact ttttttccgt
    52441 ttttattgga atttcatttg ataaagattt gaattttatt ggaataatat taaacaaaat
    52501 tttctgaatt gtctagtata tttcgaaata tttttttaaa aataagaata aaaatggtta
    52561 taaaaacaaa atacccgaac tattagaagc tatttataca caaaaacata aattcaacac
    52621 tatttagtga tgaaaaaata ttttcgcttc aatatagttc ggaatagttc ggatattttc
    52681 aattttatga atcatttcaa tttcttcata aataagtgca gtttcttctc tctctagctt
    52741 ttgccattca tctttcaaaa tataaataaa atcaaatact tttttatttt tcaatttgct
    52801 gattccacaa aaaacctctt gaaaggcaga tccgatgatc tgcctttcaa gaggtcaagc
    52861 tctgttttca aattcttatc aatccgttag cgaattattt tgacgcacgt tttacataag
    52921 aaccttctgc tgtattgatt tccaacaatt catctgtttc gatgaagtca ggaacattga
    52981 ctactaagcc agtttccatt gtcgctggtt tacctgaacc agtgactgtt gcacctttga
    53041 tggaaggttg tgtttccaca acacgtaata cgacagttgt tggtaattga acgccgatga
    53101 cttcgctacc gaagaattgg atttttactt ccatgttttc taggatatat ttcatttctt
    53161 cttctactgt ttctacagga atttcatatt gctcatatgt ttccaaatcc atgaagaaag
    53221 ctgtatcatc catcgtgtac aaatattgta caggttttgt gtcgatgtgt gctttttcaa
    53281 atttttcttc tggtctgaac gttgtgtcgt atgttgcacc tgaacggaca tctttcagtt
    53341 tcatacgcat aactgtattt cctttaccag gtttatggtg gcttgcatcc agaactttaa
    53401 tcagtttgcc gtcttgtacg aaagtcatac cggctcttaa atcacttgct gagatcatta
    53461 tttttgctcc ttcttttctt tatcataatc aactttattg tatcagacaa ccggccagaa
    53521 aactagagta ttctctatct tttaaggtct catgcctatt tgtcagaaaa ataaacacgg
    53581 gtaaacgatg ctatcgaaat atttttttct ttcaatcctt tgacttttat tttttttcat
    53641 gctatcgtta ataaaaattt tacttggagg gatacacatg acagtcagca accaaaaaca
    53701 attgaatcgt tgctgttgta tggtgcataa aagcagcata ctatttgtca tgtctattaa
    53761 ttgcccttca tagaatgagt accaggtaac ttatcttttt atctactcaa tttttctcta
    53821 tgtctttcaa ggagctgatt taatagtcag ctcctttttt tattatcttt ttttaggagg
    53881 cccatatgat tatctcgaca attacagaag ctattggttc cacaccgctt tatcgctttg
    53941 acaatcagca ctattctatg cctaaaggtt ctgctattta tgcaaaacta gaatatttaa
    54001 atcctggagg aagtatcaaa gatagattgg gcagttattt gatcaaagaa ggatttgccc
    54061 aaggaaaaat caatgaaaaa acgacgatca tcgaaccaac tgccggaaat acaggaattg
    54121 ggatcgctct ggccgcactc acatacaaat taagaacggt ttttgttgtt ccagagaagt
    54181 ttagcttaga aaaacaacaa ttgatgaaag cattgggagc aaagatcatc cattctccta
    54241 gtgagcaagg aatcatcggt gccatcagca aaagtaaaaa acttgcagag gagatatcaa
    54301 acagctatct gcctcttcaa tttgaaaata aagataatcc tgctgcttac tatcatacgt
    54361 tagggccaga aatctttcat gaaatcaaag aaaatatcca tagttttgta gcaggaattg
    54421 ggagtggtgg aacctttgct ggaacttcta cctttttgaa agaaaaatat cccgacattc
    54481 gaataatcgg tgtagaacca gagggctctg tgttaaatgg tggtgatcca gcccctcacg
    54541 aaattgaggg tatcggtgta gaattcattc cgccgtttct ttctcccctt tcaatcaatc
    54601 agatcgagac aatctctgat gtagaagggt ttaactatac taggcagtta gcacgagaac
    54661 aaggactatt agttggaagt tcgagtggtg cggcttttgc agcagcatta agagaaattc
    54721 gtcgtttacc acctggtcat cgtgtcgtta cgatttttcc agacgcagca gaccgctatt
    54781 tatcaaaaaa catttactta taggaggaaa gaaacatgca cattcaaaca aaattgatcc
    54841 acggaggcat cagtgaagat cccacaacag gagctgtcag tgtacctatt tatcaaacat
    54901 ccacttatcg gcaagatggc gtcggccagc ctaagcaata tgaatattcg agatctggta
    54961 atcctactcg ttttgcattg gaagaactga ttgctgattt ggaaggcggt gttcgaggat
    55021 tcgctttttc ttctggtctt tctgggattc atgccgtttt ttctcttttt caagctggcg
    55081 atcatatctt attaggagat gatgtctatg gaggaacatt ccgtctattt gacaaagttc
    55141 ttactaaaaa tggtctcgag tacacgatca tagatacgag taatcttgat aaaatagaac
    55201 aatccatcaa acccaataca aaagcacttt atcttgaaac acctagcaat ccgcttctaa
    55261 agattactga tttagaaaaa agtgccactc tggctcatca acatggattg atagttattg
    55321 ctgacaatac atttgctact ccttattttc aaagaccttt agatctcggt tctgatatcg
    55381 ttgtccatag cggtaccaaa tatctaggcg gacacagcga tgtagtagct ggtttagtga
    55441 cttctaacca taaagatcta gccgatcaga tcggatttta ccaaaatgct atcggagccg
    55501 tacttggtcc ccaagatagt tggttacttc agcgcggaat caagacacta agtgttcgta
    55561 tggaggaaca tcaaaaaaat gcttttgtgg tagctgattt tctattttct catccagcag
    55621 tagaaaaggt ctactatcca ggattacccc atcatgaact ccatggagtt gctaagcagc
    55681 agatgagcgg ctttagcgga atgatttctt ttactttaaa aaatgaagaa actgctattc
    55741 catttgttga atcactccaa ctatttactt tagcagaaag tttaggtggc gtagaaagtt
    55801 tagtggaaat tccttctgtc atgactcatg cgtctattcc aaaagaaaaa cgagaagagg
    55861 ctggcataaa ggacggcttg atccgtcttt ctgtaggaat tgagtatggt caggatctca
    55921 taaacgattt agctcaggca tttgacagaa tcaagaacta gaagtcccaa taaacgactt
    55981 agcagaaaaa tctaaaaaat atttcagatt gctacacctt ggaaacgata agtgttagaa
    56041 tcaagtagaa agacgttttt gtaaatttca ctaaataatt ctttagtgaa aagcatcaaa
    56101 acgaatgaac aaacagatag gagtcttaca aatgagaatg aatgtcgaaa gttttaatct
    56161 tgaccataca aaagtcaaag caccttatgt acgtgtagct gatcgaaaaa cgggtgcgca
    56221 tggcgatgtc atcattaaat acgacgtccg ctttaaacaa ccaaataaag aacacatgga
    56281 catgccaagt ctacattcac ttgagcactt gactgccgaa ctaatccgca atcacgcaga
    56341 ttacatcgta gactggtctc caatgggatg ccaaacaggc ttttacttga ctgtattgaa
    56401 tcatgaaagc tacgaagaca ttttagatgt tcttgaagca acaatgaaag atgttcttga
    56461 agctactgaa gtacctgcaa gcaatgaaac acaatgtggc tgggctgcca gccatacact
    56521 agaaggtgca caagctttgg ctcgtgaatt tttagcaaaa cgcgatgaat ggtctgaagt
    56581 agaagcatag tttctaaaag aacgtaaaga tgagaagcaa tatagctatc ttatcttcgt
    56641 attttattaa atatttattg tctgaaaaga gttctaaacg ggaaaacaaa tagctagttt
    56701 tcagtttagc gctcttttta tt
//
LOCUS       DAXLPY010000010        52100 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.010, whole genome shotgun sequence.
ACCESSION   DAXLPY010000010 DAXLPY010000000
VERSION     DAXLPY010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.010"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            290..1135
                     /locus_tag="ACF3UF_000705"
     CDS             290..1135
                     /locus_tag="ACF3UF_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3670857.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="ACF3UF_000706"
     CDS             1416..2636
                     /locus_tag="ACF3UF_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFD3670858.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="ACF3UF_000707"
     CDS             2633..5353
                     /locus_tag="ACF3UF_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3670859.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="ACF3UF_000708"
     CDS             5337..6281
                     /locus_tag="ACF3UF_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3670860.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6350..7360)
                     /locus_tag="ACF3UF_000709"
     CDS             complement(6350..7360)
                     /locus_tag="ACF3UF_000709"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3670861.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7540..7884)
                     /locus_tag="ACF3UF_000710"
     CDS             complement(7540..7884)
                     /locus_tag="ACF3UF_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFD3670862.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7877..8311)
                     /locus_tag="ACF3UF_000711"
     CDS             complement(7877..8311)
                     /locus_tag="ACF3UF_000711"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFD3670863.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8449..9186
                     /locus_tag="ACF3UF_000712"
     CDS             8449..9186
                     /locus_tag="ACF3UF_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3670864.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9179..10390
                     /locus_tag="ACF3UF_000713"
     CDS             9179..10390
                     /locus_tag="ACF3UF_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3670865.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10594..11376
                     /locus_tag="ACF3UF_000714"
     CDS             10594..11376
                     /locus_tag="ACF3UF_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFD3670866.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11446..12108
                     /gene="trmB"
                     /locus_tag="ACF3UF_000715"
     CDS             11446..12108
                     /gene="trmB"
                     /locus_tag="ACF3UF_000715"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFD3670867.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12206..13960)
                     /gene="ade"
                     /locus_tag="ACF3UF_000716"
     CDS             complement(12206..13960)
                     /gene="ade"
                     /locus_tag="ACF3UF_000716"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFD3670868.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14092..15021
                     /gene="comGA"
                     /locus_tag="ACF3UF_000717"
     CDS             14092..15021
                     /gene="comGA"
                     /locus_tag="ACF3UF_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFD3670869.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14978..16027
                     /gene="comGB"
                     /locus_tag="ACF3UF_000718"
     CDS             14978..16027
                     /gene="comGB"
                     /locus_tag="ACF3UF_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFD3670870.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16024..16302
                     /gene="comGC"
                     /locus_tag="ACF3UF_000719"
     CDS             16024..16302
                     /gene="comGC"
                     /locus_tag="ACF3UF_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFD3670871.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16277..16747
                     /gene="comGD"
                     /locus_tag="ACF3UF_000720"
     CDS             16277..16747
                     /gene="comGD"
                     /locus_tag="ACF3UF_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFD3670872.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16719..17066
                     /locus_tag="ACF3UF_000721"
     CDS             16719..17066
                     /locus_tag="ACF3UF_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670873.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            17029..17454
                     /gene="comGF"
                     /locus_tag="ACF3UF_000722"
     CDS             17029..17454
                     /gene="comGF"
                     /locus_tag="ACF3UF_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFD3670874.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17426..17785
                     /gene="comGG"
                     /locus_tag="ACF3UF_000723"
     CDS             17426..17785
                     /gene="comGG"
                     /locus_tag="ACF3UF_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFD3670875.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17957..18964
                     /locus_tag="ACF3UF_000724"
     CDS             17957..18964
                     /locus_tag="ACF3UF_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3670876.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18989..20173
                     /locus_tag="ACF3UF_000725"
     CDS             18989..20173
                     /locus_tag="ACF3UF_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFD3670877.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20610..22193)
                     /gene="abc-f"
                     /locus_tag="ACF3UF_000726"
     CDS             complement(20610..22193)
                     /gene="abc-f"
                     /locus_tag="ACF3UF_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFD3670878.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22298..22426)
                     /locus_tag="ACF3UF_000727"
     CDS             complement(22298..22426)
                     /locus_tag="ACF3UF_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670879.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22771..22914)
                     /locus_tag="ACF3UF_000728"
     CDS             complement(22771..22914)
                     /locus_tag="ACF3UF_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFD3670880.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23136..23615)
                     /locus_tag="ACF3UF_000729"
     CDS             complement(23136..23615)
                     /locus_tag="ACF3UF_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3670881.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23688..23972)
                     /locus_tag="ACF3UF_000730"
     CDS             complement(23688..23972)
                     /locus_tag="ACF3UF_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670882.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24050..24244)
                     /gene="ssrS"
                     /locus_tag="ACF3UF_000731"
     ncRNA           complement(24050..24244)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACF3UF_000731"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24316..25602)
                     /locus_tag="ACF3UF_000732"
     CDS             complement(24316..25602)
                     /locus_tag="ACF3UF_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFD3670883.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25740..26411
                     /locus_tag="ACF3UF_000733"
     CDS             25740..26411
                     /locus_tag="ACF3UF_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFD3670884.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26377..26865
                     /locus_tag="ACF3UF_000734"
     CDS             26377..26865
                     /locus_tag="ACF3UF_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFD3670885.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26878..27825
                     /gene="prmA"
                     /locus_tag="ACF3UF_000735"
     CDS             26878..27825
                     /gene="prmA"
                     /locus_tag="ACF3UF_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFD3670886.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27826..28590
                     /locus_tag="ACF3UF_000736"
     CDS             27826..28590
                     /locus_tag="ACF3UF_000736"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFD3670887.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28823..31036
                     /locus_tag="ACF3UF_000737"
     CDS             28823..31036
                     /locus_tag="ACF3UF_000737"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFD3670888.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31047..31493
                     /gene="dtd"
                     /locus_tag="ACF3UF_000738"
     CDS             31047..31493
                     /gene="dtd"
                     /locus_tag="ACF3UF_000738"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFD3670889.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31664..32923
                     /locus_tag="ACF3UF_000739"
     CDS             31664..32923
                     /locus_tag="ACF3UF_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFD3670890.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33012..33959)
                     /locus_tag="ACF3UF_000740"
     CDS             complement(33012..33959)
                     /locus_tag="ACF3UF_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFD3670891.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34353..35645
                     /gene="hisS"
                     /locus_tag="ACF3UF_000741"
     CDS             34353..35645
                     /gene="hisS"
                     /locus_tag="ACF3UF_000741"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFD3670892.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35660..37429
                     /gene="aspS"
                     /locus_tag="ACF3UF_000742"
     CDS             35660..37429
                     /gene="aspS"
                     /locus_tag="ACF3UF_000742"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFD3670893.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37538..38413
                     /locus_tag="ACF3UF_000743"
     CDS             37538..38413
                     /locus_tag="ACF3UF_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3670894.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38679..40562
                     /locus_tag="ACF3UF_000744"
     CDS             38679..40562
                     /locus_tag="ACF3UF_000744"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFD3670895.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40637..40921)
                     /locus_tag="ACF3UF_000745"
     CDS             complement(40637..40921)
                     /locus_tag="ACF3UF_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFD3670896.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40911..41645)
                     /locus_tag="ACF3UF_000746"
     CDS             complement(40911..41645)
                     /locus_tag="ACF3UF_000746"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFD3670897.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41774..42397
                     /locus_tag="ACF3UF_000747"
     CDS             41774..42397
                     /locus_tag="ACF3UF_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFD3670898.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42589..43710
                     /locus_tag="ACF3UF_000748"
     CDS             42589..43710
                     /locus_tag="ACF3UF_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFD3670899.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43717..46845
                     /locus_tag="ACF3UF_000749"
     CDS             43717..46845
                     /locus_tag="ACF3UF_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3670900.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46864..50058
                     /locus_tag="ACF3UF_000750"
     CDS             46864..50058
                     /locus_tag="ACF3UF_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFD3670901.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50204..50911)
                     /locus_tag="ACF3UF_000751"
     CDS             complement(50204..50911)
                     /locus_tag="ACF3UF_000751"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3670902.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51676..52074
                     /gene="spxA"
                     /locus_tag="ACF3UF_000752"
     CDS             51676..52074
                     /gene="spxA"
                     /locus_tag="ACF3UF_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFD3670903.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT        17097 a         9064 c        10780 g        15159 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 ttgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttcttt tattttgatg
     6361 aatcagttgt ttcttcagtt gaagattctt ttgttgaatc agttgatttt gtgtcagaac
     6421 tctttgttga agctgtagtt tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg
     6481 cactcaacac attttcaaag gcatcatctt tgatttttac atttgcatct tttaattctt
     6541 caccgattac tttagttgtg aatgcattgt cacttagttt agtttcagta gcgatatctt
     6601 ttagttgatc tttgtattta tccatgtcat tgcctttatt ttggtttttc accattttga
     6661 caacgtagta ttctgtcgca taagaagtag gatttgttgt agtaataaca tcggagatct
     6721 caccgtcttt caatttgaaa gctgcttctt ttacttctgc aggaatagtt gttgtcgttg
     6781 agtcgaattt aactttaccg ccatcttctt ttgtctctgt atcagttgat ttgtctttgg
     6841 ctaatttaga gaaatcatct ccatcatccg ctgatttttt cacatctttt gcttcatctt
     6901 cacttgataa tttgatgatt tgtgcttcta cttctggatg gaaagatttc caagcagttt
     6961 tcaaatcgtc atctgtaata tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt
     7021 tacgaatata ttctttataa gtatctttcg tatatccagc agcttctaat tgtgattcaa
     7081 aagtatcacc taatgatttc gcttgtttgt cgtattctgc atccacttgc ttatcggtta
     7141 ctttatcgcc atatttgtta ttgaatactt tataaatgat catccgttgt actaaggatt
     7201 ggttcgatga ttcaagtttt gcttcatcat agaaatcaga tacagtgatc gttccgcctt
     7261 tcatcgttgc gatatcttta ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca
     7321 acgcactagt agctgccaaa ataattgatt tttttttcat taaaatttgc actcctgtaa
     7381 ttagttatta tttttatata ttaactatac catatcccat ttcctttaaa aacgttgtcg
     7441 tggtagtttc aaacaaaatt caaaatttca tcacattcct aggaaatacg caaacttttc
     7501 tcacttatat agttaaatct gttgagaaaa taatcattat tatatttgtt caggatactc
     7561 tggcagatca gcttttagtt tttctacttg ttcattgatt tgtgtgatac gtggttcggc
     7621 ttggaattta aaatcttcga tatctttttt gattgcttct tggaaagcag gaatcacaga
     7681 ttcagctgtt tcttttgttt cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa
     7741 atcatttgtc agagttgttg cttcttccaa ttcttcgatc agtttctttc ttgtttcatt
     7801 cccgctcctg ggcgccaata acagacctcc gacagtgcca gcagcagctc caaataacag
     7861 tcctttgaaa aagtttttaa tcatcgcagg acacctgctt tacgattgtt tcttgaatag
     7921 cttttagttc ttccgatcca taactatctt gatgattgac aaagtgaata gaaaaatcat
     7981 cctctttgct gtagcgaggg actaaatgga tatgtgaatg aaaaacagat tgataggcta
     8041 gttcacggtt gttattcaag atattaagac ctttcatttc tggaaaagct ttttccaatg
     8101 cttgagcaat cttaggcaca cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa
     8161 aaatatctgc tacatgacgt ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga
     8221 tgtctaaaaa agcatagacc ttgtcgtctt catatatttt atagcttggg atttcttgat
     8281 tgatgatttt gcaaaaaata cagttttcca tataaaacat cctttctata aagaataaat
     8341 acttcagctt aactttacca taagttaaag ctattgtaag gaaaaaaaca aaataccgtc
     8401 attttcttcg tggtataata aataaaaata aatggcggag gaaaaagaat gagtttaatt
     8461 atcgatcatg tcacaggggg gtacggacat ctccctgtgt taaaagatat cagtttcgat
     8521 gtacagcctg gagagatagt agggttgatt ggactgaacg gagcagggaa aagtacgacc
     8581 atcaagcaca ttatcggtct gctggaagct tcaaaaggaa cgatagaaat caatcatcta
     8641 tccttaaaga aaaatacgga agaatatcgc aaacaaattg ggtatattcc agagactcct
     8701 tctttatatg aagaattgac attgagagaa catatcgaag tcactgcgat ggcctacgat
     8761 atacctatgg atatagcaat gaaaagagca gaaaagttgt tggagacttt tcggttatct
     8821 aatcgtcttg actggttccc agctaatttt tcaaagggaa tgaaacagaa agtgatgatc
     8881 ttatgcgcct ttttgatcga gccttcttta tatatcatcg acgaaccatt tttaggcttg
     8941 gatccactag ctatcaatgc attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc
     9001 ggtattttga tgtctacgca tattttagct actgcagaaa aatattgtga tcgttttgtg
     9061 gtcttacata acggagagat acgagcagac ggttctcttg agatgttgag aaaagaattt
     9121 cagctgccgg attcttcttt ggacgaaatc tatattgctt taacaaagga gcaggcacat
     9181 gagtagtttt tttcaaaaac gtttagcaag acatcaaaag aaaatgatga aatatatgcg
     9241 ttatgtattg aacgatcatt ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt
     9301 atattattct aattggttga aaaccctgca gccaccgttt gcaattggag ggctcataat
     9361 ctctgtattt tggatgctct gtttattcgt gggtaagatg gctacttttg cagaggcagc
     9421 agatattgtt tttttacttc ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt
     9481 tcgctattct tgcatttttc cgttgatctt tttgatattg gcatgcggat tggccatgcc
     9541 attagtggtg gttagtacgg agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt
     9601 atggagtttg aaattcagtc atctgcaaat caagagagca gaattgtttc gactagatca
     9661 acaagttatt cgttattgga aattaggctg gtttttttct tctctgatct ttttgtttct
     9721 atcattttat tggctaatat gggcaggaat agcaggtgca ttagtacagg caagtctata
     9781 ttactggttt ttgtggaagc aacaagaaaa aggattggat tgggagaaaa tggtgcatgt
     9841 agaagaacat aggttgcatc agatctatca atttatcaat ttattcacag atgttcctga
     9901 aattacggca aagatcaaaa gaagacgcta tttggatcct atattgactc atattaaaag
     9961 agaatcaaaa aacacttatc tttacttgtt tgcaagaaga ttggcaagag gttctgattt
    10021 tagtggtctt tatttccgat tagtaattat aggtgggtta ttgattgccg gagtagtcga
    10081 cttttatttt agtctgatta tcggtttctt atttttatat ttgatcggtt tccaactgtt
    10141 acctttagcg aaccagttcc gctatatggt tctcgttcag ctttatccaa tccataagaa
    10201 tcagaagaag caggcgattc agtatctact cacatgggta ttaattatcg cgtcggttat
    10261 ttttggtttg attgctgcag tcgtattaga tgggcagcag cgatgggttc cgctagcggc
    10321 ttatttgatt gttactatgc tctttgttaa actatatgta ccaactcgtt tgaagaagat
    10381 gtcagactga aaacaaagct gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca
    10441 gtaagaatgc tgttcgttct attttttttg agaaaagctg gttttttgaa tggcaattaa
    10501 atgaaaaaga acgtatatgt gcttgacgtg tagtgttcag gcgactagaa taataagtac
    10561 tgcaaaacaa agagtaagag gacgggagaa tgcatgatgg agtttcagtt agaccaagag
    10621 tggcggttac gtcccatcaa aggcgacaca ggaaaaacat acataggcat gcgtgatgag
    10681 gacaaagtct ttattaaacg aaacacgact ccgatgttgg ctgctctttc aagggaagga
    10741 attacaccaa aacttgtttg gacaaaacga acggggaatg gcgatacttt gacagcacaa
    10801 gagtggctgg aaggtcgctt gctgactcct aatgagattg gtcaaagaaa cgacgtgatt
    10861 gatgttttgt accatttaca tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt
    10921 ggtcgtgtca tgacgccgga gaagatgctg caaaaatatg aaaaagaatt accggaagaa
    10981 ctccagaaaa atcaatttct gcaaattgtc catcgttttc ttcgtgagca gatcccgtca
    11041 atagataagg aaaacttatc agtagtacac ggagatgtaa accatcgtaa ttggttagta
    11101 tgtaaaaatt atttatatct agtcgattgg gattcaatca tgtttgcaga ccctgcggtg
    11161 gatattgcaa cgattttagg aaattatgtg ccactgtcta gctggaatca gtggctgatc
    11221 agttatggca tacgcccgac tgacgaaatg cttgaaaaat ttcattggta tgcggccatg
    11281 aatttgctcc aagaaatcac cagatattgc aaacgtgaag atcatcgacg gatgaacgaa
    11341 gaaattttac aattaaaacg aattttcagt ggctgaggtt tggcccaaac tctgcggaga
    11401 tttggccaga cctttttaat tagaggaaag gaatggagat aaataatgcg tgtccgaaat
    11461 cgtccgggag cagcggaaat gttagcggct cacccgaatt ttgtaattag tgatccaaca
    11521 ttgtggaagg gaaaatggaa tgaattgttt gaaaacgatc atccaatcca cattgagatt
    11581 ggtatgggga aaggccagtt catcactgga atggcaaaag cccatcctga aatcaattat
    11641 attggagtag aaatgcaggt cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa
    11701 ccgcttccta acctgaaact tctacatgtg gatggatcag cgttgacaga gtatttcgct
    11761 gacagcgaag tagatcaaat ctatctgaat ttttccgatc catggccaaa aaaacgtcat
    11821 gaaaaacggc gattgacata taagactttt cttgctgtag atgaacagat tcttcgtcca
    11881 aatggagaaa tccatttcaa aacagataat caaggattgt ttgagtattc tctggcaagt
    11941 ttttctcaat atggcatgat cctcaaacag gtatggttag atttacatca aagtcaattt
    12001 gaaggcaata ttatgacgga gtatgaagaa aaattttctt caaaaggtca acgtatttat
    12061 cgagtagaag ctcaatttca agataagacc aaaaagaaaa gtctgtgaaa ctaactttct
    12121 gctttcataa aaacattaat atccataaat aaatctcaga aaatgaacat tacagatgta
    12181 atgtattttc tgggatttat ttgatttaaa atgtatttat ttcatcggtt tttccacaag
    12241 gtggaatcaa ttggaagcga gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg
    12301 gtatgacaga taatgttaag aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc
    12361 ctagttgatg tgctttagtt attaattcat tcaactgttc atagacgatc gaaaaaggtt
    12421 cctgtgtcat gattccgcct ataggaagag aaacacaagc tatttcctgc tgtttgttga
    12481 caacggtcat cccgccacct ttttgaatca aaagattagc agcatacagc atatcctcgt
    12541 cgtttgtccc aacgacaact agattatgcg agtcatgggc aatcgttgtc gctatcgctc
    12601 cttgtttcag ctgaaatcct ttcactatgc ctaatccaat gtttcccgtt tgatggtgac
    12661 gctcgatcac cgcaatcttt aattggtctt tttcgattga aggaatgaat cgttcgcctt
    12721 gtcggtccac tttttctacc aaatctttag tcactagact attcgggata atttcgatca
    12781 catgggcttg tgaagaagaa agaagcagct ctaacgaatg tggatttaat ggttgagcgt
    12841 ttagttttgg cagacaacac gtatatgaat ttgaatgatc agcaaataaa tggtcttgga
    12901 gttgcccaga ttgaacaact aatgttccct tatagaaaac ttcatgaatt ggcagcttgg
    12961 taagatcgtc tgttaagaag aaatcagctt gatacccagg ggcaatcgca cctagtgttt
    13021 tcaaatcaaa acattctgct gcattcaatg ttgccatctg aatggcttgt aatggatcga
    13081 ttccaagtgc aatagcttga cggacgatat gatcgattga tccttctttt actaaatcat
    13141 tgatcagttt atcatcggtg acaaagaagc atcttcttga attttcaggt gtgatcgccg
    13201 gtagtagcga tgccagatct tttgcaacgg tcccttctcg aaccattaaa tacataccaa
    13261 gatccaaacg ttctttagct tcttttgcag ttgtagcttc atgatccgtc cgaatacctg
    13321 ctgcaggata aacatttaac tcttccatgc cgataccagc tgcatgcccg tcaatttttt
    13381 tcttatgctg gtgcatcaat tggatctttt ctaggatgtc tgtttcatta tttgctactg
    13441 cttgatagtt catgacttca gctaagccta aaacttcggg tttttgtaaa aaaggggcta
    13501 atttttttgc atttaaattt gcaccattgg tctcaaaagg ggttacaggt acacaagaag
    13561 gtagcataaa aaagatattc atgagtgttt gtcttgcatc ttctatcata aactcaagac
    13621 ctgtactccc agcaatgttt cctatttcat ggggatctgt cactacagta gtaactccat
    13681 gaagcaagga tacttttgaa aattcgcttg gtgataaaag tgagctttcg atatgcacat
    13741 ggccatcgat gaatcctggc actagatatt gcccattagc attatgtacg ctttttcctt
    13801 cgtattcacc gattcctacg atcattcctt cgcagattgc tacatctttt tccatgattt
    13861 ctttcgtaaa gacgttgacg atcttagcat gcttgatcac taggtcagca ggcttttttt
    13921 tacttgctac ttcgatatat ttccttaatg ttgtttccaa tggagtgcct cccaagataa
    13981 atttttataa gtataacata aattcggctt ttgccaatat ttttttgtaa attcatttta
    14041 tttgaaacaa aaagatcaaa aagacgtatg ttttttgtgg aggggagaat aatggaaata
    14101 aaacgattat cggatcaaat gataagtgaa agttttgcca aacatgccca agacgtatat
    14161 atattgccag cttcagaagt attttacatc tattttcgct atggaaaaaa acgaacattc
    14221 tggaagaaag tctcttcggc agatggacag caactgatct caagatttaa gtatttggga
    14281 cagatggata tcggagaaaa aagaaaagct cagttaggtg catttactta ttctttagaa
    14341 aaacaggaag ttcgtctgcg gttgtcttct gtaggagatt accttcaacg agagagttta
    14401 gtgattcggc tattatacgg tacttttgaa acaccccatc gttgctttag ttctcgagat
    14461 tttgcaacta ttttacagaa aaccgtcaga cgtggattat accttttcag cggaccagtc
    14521 ggatcaggca agacttctct aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt
    14581 actatcgaag atcctgtaga gatagaagaa ccgttttttc tgcagctaca gatcaatccg
    14641 aaaatagcac agacttatga tacacttttg aaactcgcat tacggcatcg tccagacttg
    14701 ctaatcattg gcgagataag agatgaatca actgcacatg ctgcggtaag agcagcacta
    14761 acagggcacc gggtttttgc aaccgtacat gcacgcaatc ttgaaggtac attggtcaga
    14821 atccatgaac tgacaaagaa aaaagaagag ctatctgaat gtttagctgg tgtcatttat
    14881 caagaacttt tggaagatgc caatcaccat ccttctgttt tatggagtta tcaatttatg
    14941 gaggaagaat cagtaaaaaa atcatgggag gaaagttatg aagaagctca ggaaaatatt
    15001 tggcagtcag aactattcta aaggattaac aagaagccag caaaaccagt ttgcacaaac
    15061 catgggagaa ctgcttttat ctggttttag tctgcaagaa tccctttatt tattactcac
    15121 gatccgttcg tttccacctg ttattttggc aaatatccaa catcagctaa aggaagggca
    15181 agcgtttagt gaggtacttt cgcaaatagg atatggagca gagcaactgg tacagatcga
    15241 gttagctgaa cgtcatggga atctgccgac aactttgttg gaaattgcca aacagtttcg
    15301 gcttgttgaa ggatttcgca atgatttgaa aaagctgctt gcatatccga tgctattgct
    15361 cacctttttg ctaggtatct tgtttagtat gcggttgttc gttttgcctc agcttattgg
    15421 ttcaggaatg gtcatgcaag agcattgggg tattcagctg atacaagtct ttcattggta
    15481 tgttctacta ttcatcctag cggttactct attggcttta ctagtaaggt atcgtctgat
    15541 gaagttgtct cctgttgatc agagtgaatg gataagcaga caattattga ttggaccgat
    15601 atattccttg tatcaatcgg cttatttgtc actagagatt ggaaagcttt ttcatgaagg
    15661 tttcgaatta aggcaaatca tagtctgctt aaaggaaacg aaacaagaaa gtctgattca
    15721 gcatcttgcc tctaagttga ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt
    15781 ccagaattat cgttttctat cagaagaatt cagtaaaatt gttttacagg gagaggcaaa
    15841 gggaagttta ggtaaagaac tgatttttta cagcgaatgg acaagaaaac agcttttcaa
    15901 acgtcttcat cactggatgc attttattca gccaatcatt tttttgggcg tagcggcttt
    15961 gattttatta gtttatgccg ctgttttatt acctgtttac ggaagcatag aggaggtttt
    16021 gccatgaaaa agagaaaaat atcttattat agcggtttta cattgatcga aatgctaatc
    16081 gtcttactga tcatcagtgt attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg
    16141 aatcatgtag accaagaaag tcgtgaagcg atcatccagt tggtagacac acaaaaagag
    16201 ctctatgcgc ttcaaaataa tggaagagtt cctactgtgg aggaattgtt gaatgaaggc
    16261 tatatcaaac gagaacatgc agaaatctat cagcggcctt gaaggtaagg ttttagcatc
    16321 aggatatacg ttgtttgaat cactcttact gattttatta cttacaacga tcctttcttt
    16381 tccagttctc gcattttctg catggaagaa tgaattggca gtctatcaat ttttcggcca
    16441 atttgaaaaa cgaatctatt ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg
    16501 cttttattgg aatagtgaag agaatcaaat catttttcat gttccgaatc cagataaaat
    16561 aaattgggaa gtattagata ttcctgatga gattaccttg aaacgccatg cttctattac
    16621 ttttgctgct agaaccggga atgaaagttc actaaaagct tatcaatttt attgggaaga
    16681 aaaagagcgg acgattacgt atcaattcca gatagggagt ggtcgctata caaaaagaat
    16741 tgaataaaac aggatttgtt ttgttggagt cccttacagc gcttatgatc gcttctgtct
    16801 gtgtctactt agtgagcttt ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg
    16861 aggaactgct atttattcga atgatttatg aagatatcaa gacgcagcgg atgtatcaca
    16921 aaagaccaga gcgaagggaa gaaatgatcc catacgatat ccaaattgtc gataataatg
    16981 gagtaatcga aaaagtgttt gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa
    17041 gtaattccag catttacgct gattgaatgt ctaattggac tgatgatatt gagcagtcta
    17101 ttgctcacat tcaatctttt gattcagcaa accatccaag taagtgaatt tttgcagcgt
    17161 aaagatcaaa aagagtggct aatattttta gcacaattag aagaagaact caagagcagt
    17221 cacaatgtct ctgtgaaaaa tcagcaactg cactacacga tcgaggataa acagtatatc
    17281 atcgaaagat atcaggcaat gatacgtaaa agaagaactt ccggcggaca tcaacctatg
    17341 ttaacaagta tcactgagct tcaattattg gaaaaagaac acacaatttc tttttatgta
    17401 cactttgaaa atggagaaga tggatatgcc atatggacaa aaaacgatca gtagaaaatg
    17461 ttataagggc tctattttat tttctgtctt gcttttattt cttttatgta cgtttttatt
    17521 gatggcagca ttagaaagct accgtttgtc aatggatctt aatatacgaa tcaaaaatta
    17581 ttatatagca aaaataatga agcagatggc tttatcggaa cagtctacgc ttgccgaaag
    17641 ttcggaagga gttttttact acacaactgg atctgtaaca tatcagtggg tacaacagtc
    17701 cctattctta gaggtggaag tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa
    17761 tgatacagat actagtacag aatgatggaa tgttcgtgaa aacgccctct tttctgttat
    17821 aacactgttt ttaataaaaa aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat
    17881 tgaaattttg tcaattgttc gatagaatta aacaggtgaa aaaattgtta taatatatct
    17941 agaaatgagg tgcaccatgt taccagaaaa aatggaacaa gggtttaatc aaaacctgga
    18001 agctattcag cttttacaga atgcattggg aacttccttt ttagaagcct atgtcgaaaa
    18061 tgcagaaaat ttaatagatg attatcaagt acgtgtggtg gatggagtgc cgacaaaaga
    18121 gacaacgcaa cggatcacag ctctttatga agagttgaag aaactttctt tcgagccaga
    18181 agaatggcgc agactgtctc aattactttt attgaagggc agccagacag aacatttgca
    18241 ggcgaaccat caactcactc ctgatagtat cggtttttta tttgtttttc ttattgaaca
    18301 actatacaca aataaaaaag caccggttaa gattctggat attgcggcag gaatgggcaa
    18361 cttgttatta acagttcttt taaacctatc gaatgcgggg taccaaacag aaggaattgg
    18421 tgtggatatt gatgatacat tgttggctgt cgcagcttct acaagtgatt tgacacaagc
    18481 aaatgttcaa tactttcatc aagacgggtt gcaggaatta ttaatagatc ctgtcgattt
    18541 tgcaatcagc gatttgccaa tcggttatta tccgaatgac gaaaaagcaa aagagttttt
    18601 aacaagtacc gaagaaggcc atagttatgc acatcattta ttgctagagc aatcaatgaa
    18661 atatgtgaag ccggatggtt ttggtttgtt tttgatgccg agtggatttt tagaaacgga
    18721 tcaaagtgaa gaaatcaaaa aatggtttaa agaagaaggt tatcttcaag gaatgattca
    18781 attgccagat gaattgttcc gtaataaaca atcgcaaaaa agtattttga tcttacagaa
    18841 aaaaggacca caagcacaac aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa
    18901 agaaccagag aaggtgacgg aatttttcaa cgagtttaaa aactggaaat catctgctct
    18961 gtaatcattc aacgagaagg agagtcatat gtctaaaaca attgcaatca atgctgggag
    19021 ttcaagtttg aaatggcaat tatatcaaat gccagaagaa accgtagttg cgaaagggat
    19081 cgtcgaacgt atcggtttac aagattctat ttttaccatc aagtacggcg ataatcaaaa
    19141 attcgaacaa atcatggata tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca
    19201 gttgattgaa ctgcaaattt taagctctta tgatgaaatc accggagtag ggcaccgtgt
    19261 tgttcacgga ggagaaactt atggggattc agtagtgatc gatgagaaag taatggaccg
    19321 cattgctgaa ttagcagaat ttgctccttt gcataatcct gcaaacttaa tggggatcaa
    19381 agcgtttaaa aagattttac ctgacatttt gagtgtggct gtattcgata catctttcca
    19441 ctcaacaatg ccaaagcaaa attatttata tagcttaccg gtgtcttatt atgaagattt
    19501 caaagtaaga aaatatggct tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc
    19561 aaaattattg aacaaaccga tcgaagaact aaaaatcatc acttgccact taggaaatgg
    19621 tgtatcgatc acagcagtcg atggaggtaa atccatggat acttctatgg gattcacacc
    19681 attagctggg gtgacaatgg gtacacgttc aggtgatatc gatccagctg ttctcccata
    19741 tttaatggaa aaattagaga ttgatattga tgaaatgatc aatgttttga acaagaaatc
    19801 tggtctgcta ggcctaacag gattgtctag tgatatgcgt gatcttgaaa agaactatga
    19861 aaaagaacat attcgtttag cttatgacat tttcgtggac cgcatccgaa aatacatcgg
    19921 cggttatgtg acaacgatga atggtgttga tgcaattgtc tttactgctg gtatcggcga
    19981 gaatgacgga catgtacgta gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat
    20041 cgatccagcg ttgaatgaat tgcgtggtga agaagtagat atctctacaa aagaatcaaa
    20101 agtaagagta ttagtgatcc caacagatga ggaactaatg attgcccgtg atgtggagcg
    20161 tctgcgcggc taagccaaag cattcgttag gataaaagat gaaacgcatg caagagggaa
    20221 ttcttgcatg tgtttttttt gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc
    20281 cttctttttt acaggatctt cttagggaat tttgcttgga aaagtggtca aaagggaaaa
    20341 gactggcatt ttatttattg attttcagga aaatcccaat attttatttt cattcatctt
    20401 tataagggac attacatatg taaaaagaaa aaacattttt agatcagcct cgtgggctgt
    20461 cgactttatt cttcgcttta tgtttagcta gaaaaccgat ccgaaacatt cattgatcga
    20521 ataataaaaa cttgattttc cacctgtact ttgcctgaat cgtgaaagca caggtatgaa
    20581 aatcaagttt tttgttgcga aaaaacgtcc tagtcaatca gttggccgag cggctggcgg
    20641 ctgatctgct cctgatcaat aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg
    20701 tcatggctga ctgctaggag cgttccttga tagtcttgca gcatttcttc aatttcttct
    20761 cgagcatagc tgtcgaggtg attggttggt tcatccaaaa tcaggacgtt gattttttct
    20821 aaaaagagtt tcagcaacgc caaacggatt ttttcaccac cggataaatc tttgatccgt
    20881 ttacccacat cgctttgata aaagccactt ttggctaatt gccgtcgagc gacttcttcg
    20941 tttccagtca atgtgatggc gtaagccagc aaacggctat cgggatcggc aaactgcagc
    21001 tgctgcggca aataaccgat ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc
    21061 ttttcctcac cgagtaataa tttgagtaag gttgattttc ctgcaccatt gtcgccgatg
    21121 atggctaaat gatctccacg atagactgca aaactgctgt ctttgaatag tacttgatca
    21181 gcgtactgct ggtgcaagtt ttgaatgatg aaaacttctt tgccagattt tccaccatta
    21241 gacaagcttt gcagccgatt tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc
    21301 aggcggcgtt ccagttcttt ggcttttttg aagaaggact cattgtctcc ttcatgtgcc
    21361 cactgacgaa aacgacgaat catgactttc aaccgctgga cttctttttg ctgcagttcg
    21421 taattttttg tcagctcagc caagcgagct tctttcaaga ctcgaaaacg gctgtagttt
    21481 ccgggatact caatcaatgc accttcttcc agttcccatg tttttgtggt gacttgatcg
    21541 agaaattgcc gatcatgaga aacgaccaga accgattttt ttgtattctg taaatagttt
    21601 tccaaccagc gaatactgtt aagatctaaa tgattggtcg gttcatcgag taaaagtaaa
    21661 tcggcatcgg ctgctaaaat tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt
    21721 tctgttaacc gtgcttcctg acggtgtgga atccctaagc cttgcaagat cgctgcaatc
    21781 cggtcttcta atacgtaacc gcctagttct tcaaagcgat gctgcagctc accgtaacgg
    21841 gccagacact tctctaagtt tgtatctggt tctgtcatca atgcttcgta gcgactcatt
    21901 tgctgtttga ggtcctgtat ctcagcggca gaatggagca agtagtggtt gacggtcgct
    21961 tcggaaactg taagttcttg ttcgaccgtc ccgatcttta agcctttttt gcgactgata
    22021 acaccgctgt cgacaccttc tctgccggtc aagatttgta aaaaggttga tttgccagtt
    22081 ccgttgatac cgactaaggc aattttttca ccagcttcaa tttgacagga taaatcctca
    22141 aataatggat tcccgccgat tgttttttta atagaaattg cttgtatgat catgatctct
    22201 ctccttgaga ccactcaaaa aggccatggt tatccctggc ctgtgttatt taaactcaga
    22261 ttatcatgag aaaaatacct tgagatggcc attgatttta cgtgaattca actgttttgg
    22321 acaaacttgt cccgtcaaca gcaactgtaa aaccaattgc atggctaaat gcgatatggt
    22381 atcgttggta attttcatta cttgttattt tagtcatgcg catcatagta ttttccctcc
    22441 ttcgtgtagt tgtcttttcc agtgtacctg aaagtgtcag aaagttcaac tagcgctgac
    22501 atttacttaa tatttatcga tgtgtaattc tgtcagagag ctttttttat ctgactgagg
    22561 gtaatgtctc gtggaccaca tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca
    22621 tatggtgttt gataaaaaac tttgtctaca tgacttcctt ttgccatttg cttaataccg
    22681 ttgcattaaa cagctcttct ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt
    22741 gtggttgcaa tggcaagcgg tagcctttca tcaattcttg aatgatttac cgaatgtagc
    22801 acttgccttc tcgcggtacc cgaacccgaa ataaaatttt agtttggcga taaaatcggt
    22861 atccgccatc gatacttcat attttttcgt atcagattca tcggaaactt ccacattgac
    22921 gaaccaataa gctttggcat gcttaggtcg ttttaaacca caccagggcg actaatcgcc
    22981 ctggtgttca ctttttttat tttacttgaa ctcattgact gttttccctt tattttaaac
    23041 attataaaga ccgatgagtg cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa
    23101 aaaaacctgc cgatagttgg caggtcgtct acgtgttaag ctttggtgtg gtctttagct
    23161 ggcaattggt tttctaaatc agttcggaca acaagcacat cgcaagctgc gtttctaata
    23221 acatattcag aaacagaacc aataaataaa cgttctacag cattcaatcc tgtggctcct
    23281 aacataatca aatctacttg attatcttct gggatttctc tggcaataat ttgttttggt
    23341 gagccatatt ctacgacaga ggttacatta ttcaagccag ctttcttcgc attgctttca
    23401 taatctgcca atgtttgctt tgccatttca gtagcttgtt ctgcaagcat tccatcaaag
    23461 gatgaaacgg tttggaaaga acgtgtgtca atgacatgtg ctaatagaag ttctccgtta
    23521 tttcggatag ctacattgac cgccttttta aaagctaatt cagcttcatc agaaccatct
    23581 acggcaacca tgattttttt gtattgttgt aacataagca ttcactcctc aagtcaatcg
    23641 tattgtactc ttttattgta gaacacttta gggaaaaaga gaattattta ctgctttggt
    23701 tcagcaattt tttttgcaaa tcggatactg aaggtggcag aaacaataat tacgatcagt
    23761 aaaaagacca aggcaataaa gcgttgattg aaaaaagctg ttaaaatacc cattacgcct
    23821 aaaacagcat atgcagcacc gtaaaattgt aggaatcctt gatttttatc atttttgttg
    23881 atcaatacaa aaaagatatc ctgtttatta aataaataat agctaacgaa taataatact
    23941 aaagtggcga taatcattaa aatcctaatc atgaacaaat cctccaaaat aagcaacaaa
    24001 tagaaaaagc aatttgccaa gagcaaattg ctttattctt taaaagatgg taatctccgt
    24061 taatgccgtt gtttgtcctg tagtattgat cccgcgaatt caagcaggtg ggtcccatgg
    24121 tcgtagcttc gaactaccaa atgataaggc atgttaccag cagtgacaca agacgggtcc
    24181 caagatatca ataaaaatgt tcggtcaaca cacaaagagg acaattcgaa catcacagat
    24241 ttcccacctc tatagtagca tatgaattta aaaagagcaa tgagagagct cgcagaaaca
    24301 gaaccgtttt cttgtctagt tttttggagg atgctttttc cactctttta tacggtaata
    24361 ctgttgaccc agagcctgtt catatttccc tgtatctttt ggctgataat actgagcatt
    24421 cttcagttta tctggtaaat attgctgatt gacccaagcc tgatcaaaat gatgaggata
    24481 ctgataaccc acgccacggt tgagtgattt cgcacctttg taatggctat ctctcaaatg
    24541 atcaggaaca tctccagctt tgccctctcg aatatcagca agtgctgcat ctaatgccat
    24601 gtaggcagaa ttggattttg gcgacaagca aagatcgacg acgacgtctg ctagtgggat
    24661 acgtgcctca ggcaatccca atttttcagc agctaataca gcgttcactg tacgagccgc
    24721 agcagcagga ttacctaaac ctatatcttc ataaccgata accatcagac gccggcaaat
    24781 acttgccaga tcacctgcct caactaaacg ggcgagataa tgaagtgcag catccacatc
    24841 acttccacga atcgattttt gaaaagccga aataacgtca taatgagcat ctccattttt
    24901 gtcatgggta agagcttttc tttggacaca ttcttcaatg atcgacagtg taagatgaat
    24961 ccttccttct ttatctgaag gagtcgatag tgtagccagt tccagcccat tcaatgcact
    25021 ccgcaaatcg ccgttcgttg cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat
    25081 tgcttgttgt ccaaggccgc gttctttatc ccttaaagca tgttcgactg ccaactggat
    25141 gtcttgttct gttaatggtt tgacttcaaa gatctgtgta cggctgcgga tcgctggatt
    25201 gatggtaata taaggattct cagtagtcgc tccgatcaag atgattcggc cactttctaa
    25261 atgaggaagc agaaaatcct gttttgtttt atctaatcgg tgtacttcat ccaataagag
    25321 gatcactgta ccactcattt ttgcttcttc cgctacaact tgtagatcct tttttgaatc
    25381 tgtagcggcg tttagcatgc gaaatgcata attagtagag ccggcgatcg cacttgcgat
    25441 actcgttttt ccagtaccag gaggtccata tagaatcatg gaagagagca tgcgagcatc
    25501 gaccatgcgg cgtatgattt ttccttcccc gactagatgc tgctgaccaa cgacttcatc
    25561 gatcgttcga ggtctcatgc gataagccaa tggctgttgc ataggatttt cctccttctt
    25621 gtttttacgt cccttaatta tatcatattt agcaagatgc ctagaaagaa cagccttctg
    25681 ttgttttgtt ttcatagctt atccaactaa tattgtgtat gataaagtag gtgagaaaaa
    25741 tgacggataa acaaaagata gatgaatttt tttggaataa aacgacgcca gaagtggcac
    25801 gggatttatt ggggatgtat ttggagcatg acacaccaga aggaagatta gctggatata
    25861 ttgtagacgc ggaagcatac ctaggtccag aagacgaggc cgcccatagc tatggtttaa
    25921 gaagaacacc gcgtgtgcgg gcaatgtatg aaaaaccagg tacgatctac ctttacacga
    25981 tgcatactca tcggattttg aacatcatta ctcagccaga agggattcct caaggagtaa
    26041 tgatacgtgc aatcgaaccc gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa
    26101 aaactggtcc agatatcagc aacggtccgg gaaaattagt ggaagcatta gcaattcctc
    26161 aagaacttta tggtcagtct atagcagata gttcgttacg cttagttttt gagaaaaaaa
    26221 agacaccaaa aaagatcaat gctttgccta gaatcggtat cccaaacaaa ggtgtatgga
    26281 cagaaaagcc gttgcgtttt gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa
    26341 accaaatcga gaaagattgg ggttggagga aagaaaatga aaaagaagga tctattaaca
    26401 tatttagatg aaataattga aaaacaagtg acagactatg atgtagcttt agattgggat
    26461 acaaaaaatc atacgatcga gatcgttgtt cgcttgtttg cagaaaataa agcacaattt
    26521 gagattgatg atgcagaagg gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc
    26581 gtacttcttt ttaatcctca gaaatctgtt tttgatgaac gcaattatct agcagtaatc
    26641 ccttatgaag gaaaaaaagg gttggcaaaa tcagtagctg attctttagt ggaatatcta
    26701 aatgaagtat tagctcaagg gcaaagcgat ttgcttgatt ttttggatga agacgatgac
    26761 gaagctgtat tcgagcttca ctgggataat caacaactag cagaattagt agaagtaaaa
    26821 cagcaaaatg aagcagatac ttatttaccg tacccaagtt attaaggagt gacagatatg
    26881 aaatggaatg aagtaaaagt agaaactgaa agtgaagcag tcgaagcagt tgctaatatt
    26941 ttgatggagg caggggcgag tggtgtcgcg attgaagatt ctttagatgt tgaacatttt
    27001 cagtcggatc aatatggtga gattttagat aaaaatgatt ttacatcgct gaaagaaggc
    27061 gcactagtca tggcttattt tccggaaacg actttcttac cggaaatctt gccttttatc
    27121 aaagatcgta tcacacaatt acctgagttt ggtctagcta ttggaaaaaa taaagtaaca
    27181 gttagtgaag tagaggaaag caactgggca acagcctgga agaaatacta tcatccggtg
    27241 cgtattacgc gaatgctgac ggttgcgcca agctgggaaa actaccagac agaagatcct
    27301 ctagaaaaaa ttatcacact agatcctggt atggcatttg gcacaggcac tcatcccacg
    27361 acttccttga cattgacagc actagaaaca gtcttgcgtg gtggtgaaac attgctagat
    27421 gtgggaactg ggtcgggcgt gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc
    27481 tatgcctttg atttagacga agtagccgtt cgttcggcga aagaaaatat ggatatgaat
    27541 gaaatagcca aagatgtcca tgtatcagct aacgatcttt tgacaggaat cgagattgaa
    27601 agtgatgtaa tcgttgcgaa cattttagca gatatcatct tattgatgat cccagatgct
    27661 tggcgtttac tgaagcaaac aggcacgctg atcgtttcag gaatcattga agagaagaag
    27721 caaatggttc tggatgccat gttagaacaa gggtttatcg tggatcaaat tttccagcaa
    27781 aaagactggt atgcaattat tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt
    27841 ttaaaagaat catatgaatc aaaagactat tttgttttag aaggggaaaa ctatcaccac
    27901 attgtacggg ttatgaggat ggaacccgag gatgaagttt ttttggcatt caatgatcaa
    27961 atagccattg ttgcagaaat cacggagatt actgaagagg ctgtttatct gaaagaaatt
    28021 aaaaaagaag aaaatcaaaa ggaactgcca agttcgatta ccatagcgag tggctatcct
    28081 aaaggggaaa agctggattg gatcgttcag aaatccactg aattaggagc gcaagctttt
    28141 cttggtttcc cggcatcagc ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga
    28201 caacaacggc ttgaaaagat tgctcaagag gcagcggaac aatcccatcg gcagatcgtg
    28261 ccatcagtag agttattgga aacgaaacaa gatttatttg agcggctaga tgattatgac
    28321 gtggtcttgg ttgcttatga ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa
    28381 attcttagtg aaacaaaacc agatagtcga atcttagctg tctttggacc agaaggtgga
    28441 ttatcccgcg atgaagtcga ttattttgta gaacacaaag ggatactttg tggattagga
    28501 ccaagaatcc ttcgtacaga aacagcacct ctttatttat taagtgctgc tagctatcaa
    28561 tgggaattaa tgaatccttc tttcagctaa cgttcttcat taataaaaga gtatcgacag
    28621 aaagaattga aaaaatagtc aacaatttgt ataatagaaa caattattta tacaatggat
    28681 acgaaaaatc gtttgaaaaa gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac
    28741 tgcacggatt ttgggacaat tatcaaacag atatttgtcc cgattcccgt tttaccgaaa
    28801 aaagaaaggg ggatcgattc ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat
    28861 aaagctcgtt agtcaataca tgggtcccga acatgtagca tttgttgaga aagcatgcga
    28921 atacgcgact gctgcacatg acggacagtt tagaaaatca ggcgaaccct acattattca
    28981 tcctatccaa gtcgcaggta tattagcaga tttaaaaatg gatccccata cagtggctac
    29041 aggcttctta catgatgttg ttgaagatac agaaatcact ttagaagatc tgagagaaga
    29101 atttggcgat gacgttgcta tgttagtgga cggcgtaacc aaattaggga aaataaaata
    29161 taaatcccac gaagagcagc tagcagaaaa ccaccgaaag atgctgctag caatggctca
    29221 agatttacga gttatcatgg tcaaattagc tgatagacta cataacatgc gtacgttgaa
    29281 gcacctgcga gaagataagc aaagaaggat cgctcaggaa actttagaaa tctatgcgcc
    29341 tcttgcacat cgtctaggga tcagccggat caaatgggaa ttagaagata cagcacttcg
    29401 ttatctaaat ccaaaacagt attaccgtat cgtccacttg atgcagacga agagagaaga
    29461 acgtgaaaaa tacgtaagtg gtactgttga agatattcga atagcgacag aagagctggg
    29521 gatttttgca gaaatctatg gacggccaaa acacatttat tcaatctatc gtaaaatgaa
    29581 agatcagaaa aagcagttca acgaaattta tgacttgcta gctattcgag tgatcgtaga
    29641 ttcaatcaag gattgttatg ctgtattagg agcaatccac acaaaatgga aaccaatgcc
    29701 cggcagattt aaggattata ttgccatgcc aaaagctaat atgtaccaat ctttgcatac
    29761 taccgtgatc ggtccggcag gaaatccggt agaaattcaa atccgaacac aggaaatgca
    29821 tgaaatcgct gaattcgggg ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa
    29881 agtagaacca gatggtatga cgaaacaatt aagctggttc catgagatac tcgaacttca
    29941 agacgaaagc tatgatgctt ctgaatttat ggaaggcgta aaaggagata tctttagtga
    30001 taaagtctac gtcttcacac caaaaggaga cgttactgag ttaccaaaag gatccggacc
    30061 attggacttt gcatacagta tccatacaga tatcggtaac aaaaccactg gtgcaaaagt
    30121 aaatggcaaa atggtgcagc ttgattacaa attgaaaaac ggagatatca ttgagatcat
    30181 gacttctcca aattcatttg gcccaagtcg cgactggttg aaattagttg ctactagcaa
    30241 agcaagaaat aagatcaaac gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa
    30301 aggccacgaa tccgtggtca aatgtattac agatctagga tttacgccta aagatatttt
    30361 gacgaagaac aaactgcaag aagcactcga tcgttttaat tatcaaacag aagatgatct
    30421 ctatgcagct gtagggtatg gagaagttag ccccttgacg atggccaatc gtctgactga
    30481 aaaagaacgt aaagaacaaa aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa
    30541 tcagccgaaa aaagaacctg acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca
    30601 aggggtagaa aacttactaa ttcgtatcag tcgctgctgt aatccgattc ctggtgatga
    30661 tatcgttggt tatatcacta aaggcagagg gatatccatt catcgtcgag attgtccgaa
    30721 tgttcagcct gacaaaccaa atgtagcaga acgtttgatt gaagtcgaat gggaagatac
    30781 atcgaataca cgaaaagagt atgatgcaga tttggaaatt tacggctata atcgttcagg
    30841 cttattgaat gatgtacttc aaacagtcaa tgcgctaacg aaaaatctca acagcgttga
    30901 agcacggacg aataaagata aaatggcgac gatccatttg acggttggta tccagaattt
    30961 atcccaccta aagagtatcg tggataaaat caaagcagta cctgatgtct acagtgtacg
    31021 ccggacgaat ggataggagg acagatatga gagcagttgt tcaacgggta agtaaagctg
    31081 ctgtgtcagt cgatcagcaa gaaattggaa aaattggcta cggcctactt gttttattag
    31141 gcattcatga aaccgatacg caaaaagatg tggactatct ggtaaaaaaa attgcacaaa
    31201 tgcgtatttt tgaagatgaa caaggaaaaa tgaatattag tgtagaagat gtgggaggac
    31261 aaattttaag tatctctcaa ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa
    31321 gctttgtgga agccgcacga ccagaaacag ctattccttt atacgaatca ttcaatgaag
    31381 gaatcagaag tcgcggcatc acagtcgcta ccggacaatt cggagcagat atgtcggttt
    31441 ctctcgtcaa tgatggacct gtaacgatca ttattgattc taaaaacaaa taaagtaatc
    31501 tggttttcac tagtaaaaac tatgaaacac gtcgcttaag ttagactgat aaactctaac
    31561 ttaagtggct tttttgtctg caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta
    31621 agcttaaatt atacaagtta ttttttatag gaggttgctg aagatgaaag aagtaccagt
    31681 agtagatatc aaaatcacag atttaaaaaa attgtatcaa aaaggataca acatgttgga
    31741 ggagttacgc catgaagcgg acgctcccgt cgtcaaagca aagattttca ataaagaagc
    31801 tatcacgatc tacggatcat cagcagcaaa agtattttat gatccaagga atttcaaacg
    31861 aaaaggtgct atgccaaaat tagtattgaa gacacttttt ggtcaaggtg gagtacagac
    31921 tttggatgga gctgctcatc accatcggaa aaatattttt atggatctaa tgacaccgga
    31981 aagaatggaa gattatcatc gtatcttaga taagaatctg acacaagcac ttgaagcaca
    32041 gcatggtcaa tttgaactat ttgatttaag taagatggtt ttctttacat ctatttgcga
    32101 gtgggcaggt atcaatttat cagcgatttc taaagatgag gtcgaaaaat tagcagaata
    32161 tcaaatctct atgatcagcg gaacgtttac ttctccgatt gatcacataa aaggtgtcga
    32221 gaatcgcaaa aaatcagaaa aatgggcgca aggcttgatt gaagaagctc gacaaaatcc
    32281 tgtggctgga aaagaaaatg tggcattata tgcttttgcc aatgccacag atttagatgg
    32341 tcagctttta cctctggaag tggcagctgt tgaattattg aacatcatcc gtccaacggt
    32401 tgctctaact gtgtgggcgg cattgatggg acatgcactt ttcagtagac cagatttgta
    32461 tcagcaatta aaaaatgact tttcgacgtt acaagatccg tttattcaag aaatgagacg
    32521 ctattatcct ttcttcccaa tgctacctgc gatttcgctg aaagaagtag aagtagatgg
    32581 ttatcgtata ccagaaggca gttgggttat tttagattta tatggaacag accatgatga
    32641 acgaacagtt gaagcgccag attcctttat gatcaaacgg tatgtaggga aagcaaaaga
    32701 tatttcctat aaagaagaat atgagatgat tgcacaaggc gggggaaatt ttcgacaaat
    32761 gcatcgctgt gcaggagaat ggatcactct tcatagtcta cgtgtgtttt ccgatcagct
    32821 agtaaataag tttgagttct ctgtacctga acaagattgg acgattccat tcaatcagtt
    32881 tccgacttat ccgaatagcc gagcgctact ttacaagaat tagattagca taaacttatc
    32941 gaaaaaaagg aagatcaaac agtgctgatc ttcctttttt catattacta taaattgata
    33001 aggtcaattg atcaaaatcc acgaaatgct tcatcaatgg tttgataatc ttcattggat
    33061 aaatgcaaat ctaaagcttg gacattgtca gatacttgct ctggacgctt agctccaggt
    33121 ataactacag acactcgtgg attcttcatg taccaagcta aaacaagttg cgcaggagtg
    33181 gcttggtatc ttttagcaat ggggcgaagt acatcgacag cggttaaaat ttctctgaaa
    33241 cgttctcctt ggaaatctgg atttcttttt cgaggatctc cttcaccaaa ttgtttttcc
    33301 tcaccaagtt catattttcc tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa
    33361 ctgattttgt ttttttcaag ataagggaat aattcttttt cagcctgccg atggatcaaa
    33421 ctgtatttat cttctactac atcgacatat ccatctgcat tcgcttcttt caattgttct
    33481 aacgtgaagt ttgacacacc gactgctcgg atttttcctg cttcttttaa ttcgtgcaat
    33541 gtagcaactg attcattttt tggtgtgctt tcatccggaa agtggatata aaaaatgtcg
    33601 atgtaatcag tttgcagacg ttttagtgca tcttccaccg attgtttgag aaactcagga
    33661 gaattatcaa atgttcgccc tttatttggt acatgagcag cttttgtagc gatgacgaca
    33721 cgtgagcgat catattcttt ttccttcagt acctcgccaa tcagttcttc ggaacggccg
    33781 tttccgtaag cataagcggt atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact
    33841 acttgttttc ctgtctcatc ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt
    33901 gctcctaatc caagctgttc tgcgtagact tgtgaatgtc cgattcttat ttctgccata
    33961 gctgattcct cctttttgtc tagtctaaaa caaaatacca aaaagctaaa ctaaaacgtt
    34021 tttgtgaggg gaaatagtca gatatctctt gactttgaga ctggttttta gtaggttata
    34081 agtaatatcg aatgtcaatg aaagagcgag taagtttttg aaactttaca agagaggatc
    34141 atcgaggctg aaaatgatct aaagtttcat tagcctaaag acactctgga gatggacgag
    34201 tgaaaagccg tcccgcgtac gagcgttatt cgtaagagga aagagaaatc tttcaaaatt
    34261 aggtggtacc gtgtatgaat ttcattcacc cttgttcatg atgaacaagg gtgatttttt
    34321 tatttacata gctaagaaag ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa
    34381 atgatatttt gccaggcgaa tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat
    34441 tattcagaga ttatcagtat aatgaaatgc gtacaccgat ttttgaacac tatgaagtga
    34501 tatcccgaag tgtaggggat acaacggata tcgtttcaaa agagatgtat gatttttatg
    34561 acaaagggga acgccatgtg acgcttcgac cagaaggtac agcaccaatc gttcgttctt
    34621 ttgttgagca taaattgttc ggcccagagt atgcgaaacc gttcaaaact ttttatatgg
    34681 gaccaatgtt tcgctacgaa cgccctcaaa aaggacggtt acgtcaattc catcaaatcg
    34741 gagtagaagc atttggatca gaaaaccctg caactgatgt ggagagcatg gtgatggcac
    34801 ttgatttctt caaacagttg gggatcacgc aaatccggct agtcatcaat tcattaggtg
    34861 ataaagaaac gcgtcaagcc tatcgtcaag cattgatcga ctatctttta ccttttgaat
    34921 cagagctgag tgaagactct aaacgccgcc ttcatgaaaa tccattacgc gtattggaca
    34981 gtaaagacaa acgagatcaa aaatttgtgg cagaagctcc atctatctta gattatctaa
    35041 gcgagcctgc tcaaaaacat tttgataccg ttgtttccat gctggatgca ttggctgttc
    35101 cttatgaaat cgacagtaat atggttcgcg gactagatta ttacacacat acgatttttg
    35161 aaatcatgag tgacgcacca aaaatggggg cacaagcaac gatttgcgca ggcggacgtt
    35221 atgacaatct agtggaagaa ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg
    35281 gtatcgagcg attactcttg actatggagg cagaggaagt agttatccct gcatttaatg
    35341 agttggatgc ttacgtggtc gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg
    35401 tccaagcgat tcgaaacttt ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa
    35461 aagcgcaatt taagacagca gataaagcga atgccaaatt agtattggtg atcggtgaag
    35521 atgagcttgc tagtcaaacg attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt
    35581 ttccattaga agagatatat gaacattttg atgaagtcta tgatgaaatg actttattcg
    35641 agtaggagga aaaaaataaa tggcacaaag aacgatctat tgcggattag tttccgaaca
    35701 acaattagaa caaacagtta cattaaaagg atgggtacaa aaaagacgag accttggggg
    35761 agtaatcttt atcgacctac gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga
    35821 aatcaacaaa gaagcatggg aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt
    35881 gactggggaa gttagaagac gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga
    35941 attcgaagtg attgcaagtg aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca
    36001 aattgaagat gatcaagcaa tcagtgacga aatacgtttg aaatatcgtt atttggatct
    36061 gcgtcgtcca aaaatgacta aaaacatcaa attaagaaat gcgacaacaa aagcgattcg
    36121 tcattattta gatgataatg actttctcga tatcgaaaca ccttacctag ggaaatctac
    36181 accagaaggc gcaagagact acctagttcc ttcacgtgtc catgctggac atttctatgc
    36241 gttgccgcaa tctcctcaat tgtttaaaca attgctgatg aatgctggat tcgaccgtta
    36301 ttatcaaatc gttcgttgtt tccgcgatga agatttacgt ggagaccgtc agcctgaatt
    36361 tacgcaagta gatattgaaa caacgttctt aacagcagaa gaaatccaaa cttacacaga
    36421 gggattgatt gcgaaggtaa tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc
    36481 tcgtatgacc tatgatgaag caatggctcg ctacggcagc gacaaaccgg atacacgttt
    36541 tgatatggaa ttgatcgatc taagcgatac agtcaaagaa gtagaattca aagtcttcca
    36601 aatggctctt gaaaacggcg gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg
    36661 ctactcacga aaagacatgg atcagttagg tcaatatgta ggacaattcg gagctaaggg
    36721 gcttgcatgg ctgaaagtag aagaagacgg attgaaaggt ccaattgcta aattcatggg
    36781 agaagcaaca gaagcaatca ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt
    36841 tggcgcagat aaaagtgaaa tcgtcgctgc tgcattaggt gctatccgga cacgtttagg
    36901 aaaagaatta ggactaattg atgaatcgaa attcaatttc ttatgggtaa ctgattggcc
    36961 acaatttgaa ttttcagaag aagaaggtcg atatgtctct gctcaccatc cattcacgat
    37021 gccaaaagaa gaagatatcc cgttattggc tgaagaccct gcaaaagtct atgcagaagc
    37081 ttatgatatc gtcttgaacg gttatgaatt aggcggaggt tctatccgta ttcatactcg
    37141 tgagcttcaa gaaaaagtac tagaaactct aggctttaca aaagaacaaa tggaagaaca
    37201 atttggtttc ttgttaacag ctttagatta cggattccct ccacatggcg gtattgcatt
    37261 aggattggac cgttttgcaa tgttattagc cggagaagat aatattcgtg aagtcattgc
    37321 ctttcctaaa aacggaaaag cagcagatgt gatgagtgat gcaccaagta tggtttcgcc
    37381 tttacaattg ttcgaattga atattgatgt aacgaatata gaagaatagc cgataaaaag
    37441 gtaaaaagga tttgtcgaat acgcttcttt tgacaacctt gatttaattg aaaaacactt
    37501 tataatgaag ccataacata taaagcgggg cttttccatg aaaaaaacat tcgaaaattg
    37561 ggcttatcat gattacacga ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc
    37621 agtcgcattg aatttctttt atcagccagg acatatttat tcaagtggta ttactggtct
    37681 agctcagatt ttgacgactt tgtcaaaatc actgatagga ttcgaagtac cggtatcaac
    37741 aactttgtat ttactgaata tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa
    37801 gtttacaatt ttcactttta tcacagtcac tttgacctcc ctttgtatcc atattttacc
    37861 ggaaacagtc ctatctaccg atccaatcat ctgtgcgttg tttggggggg ctgtgatggg
    37921 actaggtatt gggctagcgt tgagaaacgg cctatcatcg ggcggtctag atatcgtgag
    37981 tatcacgatt cgtaaaaaaa caggaaagtc gattggttct atttcgatct acttcaatgc
    38041 attgatcgtt tttgttgccg gaattctatt tggctggcaa tatatgtttt acagtacgtt
    38101 gtctattttc gtcagtggaa aagtaactga tgtcgtttat actaaacaaa agaagatgca
    38161 ggtaatgatc gtaacgaaac atccagaaaa agtagtaaat gaaatccaaa actgtatgcg
    38221 tagagggatc acgatcatca atgaagcaga aggtgcttat aagcatgata agcagacagt
    38281 attgatgacg atcgttacac gatacgaact gcctctactt agagaagcaa tgaaagcttc
    38341 tgatccacaa gcttttgtaa gtattgcaga aaacgtccag atacttggtc gtttctatga
    38401 ggatggcatt tagatcgagt ttgacaaaaa ttcatgaaat actgctgtag acagacgttc
    38461 gtttgtctgc agtttttttc taccatagta gaatcagcaa agaaaaactg cttttttatt
    38521 tgaaattttc ttaaagttga aaaaaagcat gtttattttt ttaaatttat gggatgatag
    38581 aaaaaaatag tagagaaagg acacgattct acttgctatt ttcacttaat acccgtatat
    38641 tacgaatgaa aaaagtttat gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa
    38701 aaaacagccg ctacatcact gggtttgatg ggctccgttc attagctgtg gtgggtgtta
    38761 tcttctatca ccttctgcca actagtatga aaggcggcta tttgggcgtt ccgatttttt
    38821 tcgtcgtatc tggttatttg atcacggatc tgctgcggca ggaatgggaa caaaatggaa
    38881 aaatcaatat ttggcaattt tatgtcagaa gaatgaagag actctatccg gcacttgttt
    38941 ttatgcttgt gacagcttcg gcttatatca ctttgtttca gcgagggctg ttaaacaatc
    39001 ttcgaggagt tgtggtcagc agcttactgt atgtcaacaa ctggtggcaa atcaataacg
    39061 gtttatctta tttcgatcga tttgctaatg agtcaccgtt tacgcatatc tggtctttag
    39121 cagtagaagg tcaaaactat ttggtttggc cgatcttgtt tgtattgttg atggtatttg
    39181 ttcgtaaaag aaaatggatc ttttatactg tgttaggtac atccttcctc tccgccatct
    39241 tgatgatgat cttgtataca ccaggaggcg atccaacccg tgtttattac ggtaccgaca
    39301 ctcgtctgtt ttctatatgg ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt
    39361 taaagaaaaa catcccgaaa caagcgaaaa atattctgaa tatcgctgga ggaatctcgc
    39421 ttttggcact gattctttgc ttcttctttt tagatgatca ttacaatttc atctattacg
    39481 gaggaatgct cctagtgagt ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg
    39541 gagcaagttt gaatcgatgg ctgacaaatc cagtatttac ttggattggc aaacgaagct
    39601 atggcattta tctgtatcag tttccagtta tgatttttta tgaagcaaag gtgactgata
    39661 ttgccgatca tgttttgttg catactttag tggaaatcac attgattcta atcatcagtg
    39721 aactttctta tcgatatgtg gagcgtccgc tagcacgttt tgattatggt cgtacattcc
    39781 aagtgatgaa aggatggttc agcaaaccga tcatcagtaa gagcaaacca tgggttgttc
    39841 caggcacatt acttgtagca attgcactcg ttggtttcgt tacggcaccg aaaaacgctg
    39901 taacagccga tcaaaaacaa ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag
    39961 aaaccagaaa caattcagaa aacaccacta gttcggttga ccaagcgatc cttgataagt
    40021 acgagttgtc caaggcacaa gggaataagg cacaaaaatt agaactaacg gcatttggtg
    40081 attcagttat gttggatgct gcaacggatc tacaagaact ttatccaaaa gtagtggtag
    40141 atggagatgt cggacgacaa ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac
    40201 aagatttgtt gaaagacact gttctgattg gactaggaac gaatggctca ttctcggaag
    40261 ctcagtttga tagtgtgatg gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc
    40321 gagtaccgac gaagcgctgg caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa
    40381 aatacgacaa tatgacgctg attgattggt acagctacag taatgaccat agtgactggt
    40441 tttatgatga tcaagtccat ccaaatcctg aagggatgac acattacatt cacttagtca
    40501 gcgaagcctt gctaggagga agttcaagta cgaacagcag tgagacaaac gtgacagaat
    40561 gatagctaca aaaaacttca ggcaaaaaca tttgtttttg cctgaagttt ttttatattt
    40621 accgtgtttt taacattcat atagattcag gaagcaaaac ggttgagtgt gtctgtaaat
    40681 aacgttcttt ttgttttcgg gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc
    40741 ttcttgaaga aaatacttct gcatggatca tcttaacagg tcttcttttt tgaagacgag
    40801 tatatttagc accagtacca ttgttatgtt cctctaatcg tctagaaaga tcggttgtat
    40861 atccaccata aaatgtctga tctttacaga ataatacgta aaaataatgt tcatttgcca
    40921 tagagcatct cacgaatctc tgcagtgtat tctccatcca tattgtaagt gatcaatggt
    40981 ggagcgactt tgaatccgtc taatttgcct tctttgattc cttcaactaa caaaatattt
    41041 gcctcttttc caggttttgg gtaaacaaat tggatccttt taggtgcaat tcgatagtct
    41101 tccatgacct gaatgatttc taagaaccga tcaggacgat ggaccatagt aaagcgtcca
    41161 tttgttttta gtagcttact tgaaatatcg atcacttctt ctaacgtcgt atgaatctca
    41221 tgacgggcga ttgccaggtg tttattaggg ttcgttttat ttgttggcag ccctttgaaa
    41281 taaggtggat tacagacgac taagtcacaa gaattatgtc gaacgacaga taagctgtct
    41341 ttcagatcga tggtgtggac agtcatttgt tcatttaaat ggttaagcgc gatactacgt
    41401 cttgccatgt ctgctagacg aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt
    41461 ttacttaaaa aaagtccaac tgcgccattt cctgcacaaa ggtcaacaat cttccctttt
    41521 ttaggtacac gggaaaagtg agcaagcagc acagcatcta aagaaaaaga aaacactttg
    41581 gaactttgga taatcttgat atcttctgcg tataattggt cgattcgttc gtcttcgtga
    41641 agcatggatt ccctccaaaa tgaaaaaaat agtcgtctgt attatactat ttttattaaa
    41701 aagaaccaag gtggcttgtc aaacctctat tttttatgca tactatgacc ataagaaggg
    41761 aaaggaagag actatgtttt atcgatttat gcgcggggta gttcgagtac tattagcctt
    41821 agttaatgga aatgcccgct atgagaataa agaagtttta ccgcaagatg agaattacat
    41881 actagttgct ccccatcgta cttggtggga cccattatat ctggcggtag ctgcagcacc
    41941 caaggaattc agctttatgg caaaagaaga actgttcaaa aatccagttc tgcgatttat
    42001 attaactcga tccaatgctt ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa
    42061 aacacctgta aagattttga aatcgacaaa tttgagtttg atcatgtttc ccagtgggac
    42121 aagacatgct acagaactta aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa
    42181 aatcgtgcca gctgtatatc aaggtccgtt gacacttggg gatctgttca agcgtcagag
    42241 agtgacagtg cgtttcggcg aaccaatcga cttatcagat atcaagaaaa cggataaaga
    42301 aggtatggcg gagatcgaac gacgaacaca agcagctttt gacaaattgg acaaagaagt
    42361 gaaccctgat ttcaaatatg aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg
    42421 gtcttttgaa tctactgtcc tgttcagttc agactttttc aatgaaaacg agggagagac
    42481 gtcaagtctg ccctcttttt gcgttccaat atgtaaaata gaagacaggt gtcatgtaat
    42541 ggatcaaagt gttataataa ttagaaggac attttttgag gtgattgaat gcgtttttta
    42601 catacagccg attggcatat cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag
    42661 cgtcatgtac tatcttctat actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg
    42721 attgccggag acttatatga taggagtgtc ccagctgttg atgccgtaga attatacaat
    42781 gaattgatgg tcgattggaa tttaaaggaa aagatcccga tttttgctat atcaggaaat
    42841 cacgatagca gtacgagact ttcagcgggt acgccatggt tcagttattc gaactatttt
    42901 ttgcgaacac agctagcaga agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc
    42961 tttcttcctt actttgaacc aattgcagcg agattatatt ttgaagatga caatatccga
    43021 acgatcaagc aagcggtagc caaggtgata gataaaatgc aggagctatt tgattcagaa
    43081 aaaaaacaag tattgattag ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa
    43141 acgaaaatcg aagtaggcgg gttggattcg atccctggtg aactacttac accgtttgat
    43201 tatgtagcac taggacattt gcataatcaa gctgctttga gacaggataa tgctcgctat
    43261 agcggttccc cattgaaatt ctctttatct gagatcaacc aaaaaaaagg cgtatggatc
    43321 gttgacctga caacaggcct ggagttgaat tttagggaga tcgaacccct gcatgatatt
    43381 gaagaaataa cagcgagttt caaagaattg ctggatcctg ccttttatca gtccgtcaat
    43441 cgggagaatt acatctatat ctatctcact gatagaacga tcatcccgaa tatgatgaac
    43501 cagcttcggc aaatatatcc tcgtattttg gggattgaac gggcaaacgg tcgagcagaa
    43561 caaacaaagc gcaaacgaaa agtactagaa atgaaagatc ctcaaaaatt agcagaagca
    43621 ttttttagtg aaatgacgga agagcagcta actgcaaacc aagaaaaatg gctcggagaa
    43681 acgttgcaag aaatcatgga aatggaatga tcaagaatga aaccgaaaaa attacaactt
    43741 aaaaattttg gtccttttat caatgagacc gtagattttt cacgtttgac agaagcaccg
    43801 ctttttttga tcagcgggaa gacaggagct ggcaaaacga cgatttttga tgggatcacc
    43861 ttcgcacttt ttggtgaaac ttccggaaga cttcgctctg gaaaagagat gcgttctttg
    43921 tttgctacac cagacgaaga aacaagcgtg actttttctt ttgaacatca gcagatgagc
    43981 tatgaaatcg aacgaaaacc agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa
    44041 aaacaggcag ccaaagtaac gttgaccatt tttgatggga aaggaaaaga aataaaacaa
    44101 atcacaaaac gtacagaagc agatcagttg atcagagaac tgatgaatct cgatgcgaaa
    44161 cagttttctc aaatcgtttt actaccccaa ggagaattcc gtaatttttt ggtttcatca
    44221 agcagtgata aagagactgt tttacgtcat ttattcggta ctcaattttt ccaacagttc
    44281 aatgagcgat taaaagaaaa agcaaaacaa cagcaacaaa aattggatca tttagagcaa
    44341 gagctgcatc ttctgcaaaa aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg
    44401 tttgaagccg ttttagccca atggacaaac catcaggcaa tactcgaaaa acaaatcacg
    44461 gaagaaaaag aagctctaac ggaacttcag gaaaaacaaa agcaactaga aaattcctac
    44521 tatcgttttg aaagcttgaa aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa
    44581 aaggaattag ctgctcaaaa agacgaaata gaggaaaaga aacgatggat tgggtattat
    44641 gaatttacgc aacgattagt cgaaccaatc cagcgcctac aagaaataaa agttgaaaaa
    44701 atagaactgt cacaaaaaag tagtgagcaa acaaagaaac tagcgatgac tacgcagaat
    44761 tatgaagagt ggcaaaaaaa tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa
    44821 gctgctcaaa aactgcaaaa caaacagatg atggtgccaa ttgtcgaatc cttacgtagt
    44881 aaaaaacaag acgcagaaca attaacaatt tcattggata aagaagaatt gaatgccgag
    44941 aagctgtatc aaaatctcgc tatctatcag gaaagaactc gaattcttca agaaaattta
    45001 ctggatcagg aaaaactgca agaagatcgt cttgcttttg gacagttaaa atatctagat
    45061 gaaaagcagc aagaaataga aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata
    45121 agagaagaac tcaaaaaagc aactgaagaa ataacaaaaa atagtcagct attgaaagaa
    45181 cagacagaac aagcagaaca gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt
    45241 cagctttttt tgcgtccagg ggagccatgt cttgtttgtg gatcaacgga acaccccata
    45301 caacaattaa aacacgaaca gccaaataag gaagatatct taaaagtaga acaacaactg
    45361 gcagaagctg agtctgctgt agaaagaact cagcaaatca ttgccaaaag tgaagcacat
    45421 gaaaataatc ttcaacaaca attatcagat ttagaacaaa aaatcatggc aacgaatata
    45481 caattggctg aacaagaaga acacttgcaa caggctttga aaaaggcatt tcctgagata
    45541 acagaacaaa aaacaaaaac aactcttgta gtaatcgaac aatctttaga tagacgaaaa
    45601 agcaagatgg ccaatgcaag aatagagctg gaagaaataa gacaacaagc agaaaagctc
    45661 gaacaacaat tagctgtcta caaacagcag cagacagaaa aaaataatca gctccagcaa
    45721 ctgcaaggag aaatcaaaag tttagaacaa caattgcaag atacggatag taactgttta
    45781 gaagaggaga tacgacgact tgaaaaacag ttagaagaag actcgaatca actagctgtt
    45841 gagcagaaag caggagtgca attgttgcaa gatcttcata cgcttcggac acagcttgat
    45901 cttcaacatg aacaaataga aaaaatagat gaaaaaatag aaaaggaaca agaaagaata
    45961 gctaaaaagt tagaaagcca gtcgtatttt tcaacaattg aagaaatctg tgcatttgca
    46021 caacagcaag cacaatataa agaaaaccaa cgtacagtta cttcttatca tgaagagcaa
    46081 ttagtgacag ctgaccggct gcgtcaatta gaaaatatcc agctaactga gacattccca
    46141 gatacagaag agatcagcca acagttagaa gaaataagac gtatgatcga aataaagcaa
    46201 gaaaagatat acggtttaca agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt
    46261 ctttcgattt atcacacaag ccagacgaaa ttagatgagc ttacgcaatt acagcagctt
    46321 tcgcaaacat tcaacggaga aaatcctaag aagactagtt tggaacggta tgtgcttcag
    46381 gtttatcttc aagaagtgtt acaagtagca aatgatcatc tccaacgttt aacgaaaaat
    46441 cgttatcaat ttgagctagc ggataccatt ggcagttatc gagggaaaac cggattagaa
    46501 atcaatatct atgatgatca ggcaggtatg tctcgaagtg cgcataccct gtctggcggt
    46561 gagagtttta ttgcagcact ttctttagca ttagctcttg ccgatgtgat ccagacacaa
    46621 gctggtggtg tagcaatcga tgcattgttt attgatgaag gatttgggtc attagatgaa
    46681 gaagctttgg aaatggcaat ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc
    46741 ggcatcatta gtcatgtaag agaattgaaa gaacgagtat tacaacaaat aagaattgat
    46801 acagaaggta gcggacaaag caaaatacgc tatcaacttg gataaaaagg gagattggta
    46861 actatgaaat ggagtattcc agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa
    46921 ggccgagtgt tatcggttgt ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg
    46981 ggcagtgaat tgtatatggt tgatttggat ggtacagcaa aagagataga ttactgccaa
    47041 tgtccctatt gggaggaaca taaatattgt aagcatacag ttgctgtgga actttattta
    47101 cggtcgaaaa atctatctcg tatcatgaaa aaagaccagc caatgctaga accggtaaaa
    47161 gcaacaagtg agggagaaat cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat
    47221 cctcaagcgg tgcaaccttt gattattgaa taccaagtag aaacgattga gactaatcag
    47281 tatcacccag agctttctat tttggcactt tacttgcgta tcggttcatt ggcatcaccg
    47341 aaaaaaacat atatcgtaaa aaacatctat gattttttac aagcttacac agaaaaagaa
    47401 acttacactg ttaataaaca gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa
    47461 gatcaaaaaa tactcacgca tcttgcagga agtgctcaga cgcatcaatt attaggtacg
    47521 aacggcttac aagtcaaagg aaaactagat aaaagatatc tgcttctccc agtagaacaa
    47581 gcccgcttcc tgttagagca gatgaatcag actacacgtt tgcatctgca gataaatgaa
    47641 caaaacgatc aaggaataca attttccgat caaaacaaac ctttatcatt caaagtggaa
    47701 aaatttggag aagattattt gctgcaagca ttgaatgatt ttgatttttt ctttatgcat
    47761 tatcagtggg gagttatcca agggacattt tattctctga cgaaatatca acaaacggtt
    47821 tatcaaactt ggaaacaatt gattcgccga ttggagaaac cagaagtagt gttcaagaaa
    47881 aaagaattac cgtctttgtt taaagagatt atccctctgc tgtcagagat cggcgacgta
    47941 gctattgccc ctgcagtaga agaggaagta gcagatatcc ccgtcgaatt tattttcttt
    48001 ttccgaaaag caaaaggaaa aatccaagct cgagtcgatt tcgtctatgg tgaagtcatc
    48061 tattcgactg acccgaagca tgaggtctcg acagaacagg cttttcaggt gttacgtgac
    48121 acagtagaag agaaacgagt acttgatcta ttcagaatgt atcgctacca gaaaaatgaa
    48181 actggttatg aacgtccatt gccaagcggg gaagaactat atgccttttt ccgcacagaa
    48241 ctatctgtct tccgtcagtt tggtgaagtc agacttggaa gaaaattgcg agagttgtat
    48301 ttagatgcgc ataaacatca accgaaaatc gaagtaaccg agaccggttc atggctcgat
    48361 attcgattcg atgtgacagg gatagaggag caagaaatcg atcatgtcct gcaaagcttg
    48421 ctgagaaatg atgcttttta tacattagaa aatggtcagg ttctttcttt tgattcagaa
    48481 gaatttcaac aaacaagcca agtgttgcaa caattacggg aatcgatacg tacagaagaa
    48541 ggaacgatcc atgtacctaa aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc
    48601 aatgctactt ttagtgaatc gttccaaacg atggtacaag atctcattca tccagaaaga
    48661 taccaggcac agcttcccaa aggattgaat gcaacgatga gagattatca aaagcaaggt
    48721 tttcgatggt tgaagatgtt aggtcattat cagtttggcg gtattttagc cgatgaaatg
    48781 ggacttggga aaacactaca gacaattgcc tttttacttt cggaaaaaga agaacggaaa
    48841 agcttctctg ctttgatcgt agcgcctgcg agcttaattt acaactggca ggcagaggtg
    48901 agaaaattcg ccccttcttt aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa
    48961 gaattactgg ctaaagacac agatatccga gtgacttctt atgccagctt aagacaggat
    49021 ctagctaatt atcagtcgca aaaaattgat tatttgattc ttgatgaggc acaaatggtc
    49081 aaaaatagca gtacgaaaac tgcacaagca ttgagagaat tagctgtacc tcagcggttt
    49141 gcactgagtg ggacaccaat cgagaataat ttagaagaat tgtggtcatt gtttgcaacg
    49201 attatgccag gatttttccc gactaaaaca aaattcaggg aacttgccgc agaagaaatt
    49261 gcgcaaatga ttcgaccgtt tattttacgg cgagataaac aaactgtgtt gaaagacttg
    49321 ccggaaaaaa cagagatgaa tctatattct gcacttacag aagaacaaaa aactgtttat
    49381 ttagcttact tgcgtcaaat gcgtgaagaa atcacatcaa tggattctga agcattcaag
    49441 aaaaaccgga tcgggatact tgctggtctg acaagactgc gacaaatttg ctgcgatcct
    49501 cgtctgttta ttgaagatta ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta
    49561 ctggtagctg ccaaagagaa caaacgaaga gttttgctgt tttctcaatt tacagggatg
    49621 ctgactatct tgcaagaaga gttagccgag ctagggatct cgacatttta tttaagaggc
    49681 agtacgaaac cacaagatcg gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat
    49741 gtttttctga tttccttaaa ggctggggga actggattga atctcacggg agcagatacg
    49801 gtcatcttgt atgacctttg gtggaatcct gccattgaag aacaagctgc tggacgtgca
    49861 catcggatcg gacaaaaaaa tgtggtagaa gtgtggcgta tgatctctga aggaacgatt
    49921 gaggaacgca tggattcact ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa
    49981 ggtaatgaag aacagttgac gaaactgact gaagaagaca tccgcatgat tttaagtgta
    50041 ggagaaatcg aggagtaaga gactcgaaaa agcgttcagt aatgggtaag aaagcctttc
    50101 taaagaagcg attgtttatt tgatttaaaa aatagcaagg aggctgggat tccattttat
    50161 cccagcttcc ttgctatcat ttttttattt ctatttttaa aggttataca aagattgtct
    50221 tcattgtctc taacagctga tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt
    50281 caattttgcg ttctcgatgg ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta
    50341 gaacatcatt gtcgtaatta tcgccaacgt ataaggtctc ttctggaagc atatgaaatt
    50401 ctttctcagc cagctgaaaa atctcttttt ctggtttttg gaaacctgtt gcttgagaaa
    50461 tgagcatatt gcgggaagga atccaattgt tcaattgaag ttgcttcagt ttttttgtct
    50521 gatggtcagt cggcccattt gtgataattc ctaatgggac attcttttcc ttcaagaaat
    50581 cgagggtttt tttgacctcc tcatgcaagc agatattatc aagttcttcc tcgtaaattt
    50641 tttgaaataa gaggccatct tcttccgtaa tatgagggta gtctaaatct tttagtgatt
    50701 ggctgatccg atgtgctcgc atatattcta gtgtccaatc tcctgccatt acttttggga
    50761 agttttcatc actatgatgg cggaaccgga tatatagtgg atgcatatct gcatctgaaa
    50821 caagcggaac gactcttttg accgcgtttc gaaatggctg ctgctgatca tacatcgtat
    50881 catcaacatc aaacacaact gatttaatca aaattttaca cgcctttcgg ttttcattga
    50941 ttttttcaca aatccttgac tattgtaaca gaaaaaattg tctaaaaaag ctgataaata
    51001 aaggtttttc ttactatatt tctatttcct tgacagaata aggtttttat atttcagttt
    51061 ttttcactaa aaatcgtgaa acacgtcaat aagtttgatg aacaaattaa tcattatggt
    51121 agaagtcgat tgatttattt taatgcaatc tctgtggaat tttcgaaaga tttatttttt
    51181 taatacagtc tcaatataac tattcaaaca taaaataacg ttatttgatt tatttgttta
    51241 tagtaaattt tatttagtaa tcattgcttt aaaatactac gcttatataa cagagaaaat
    51301 aagcgttata ataaagaaca gtattattta aaatgacaga aaacattact attaaagaaa
    51361 taaaaaacat aaaaaatctt aagaaatcgg tttcatttag cttttgagat aaaataatag
    51421 tacagtttta tacgctgttt catatgttta gaaaatttga attagatttg aaaactctaa
    51481 tttttaaatg ataaaaaaag cgagaatgct ggttttactg tatattaacc ttagataact
    51541 ttcatttttt taaaaaaatt atgaaaaaaa ggtagctatt taaaagttga ttatgtataa
    51601 tagaaacaga tgggagatta ttatgatctt ctgttacaaa aaagtgattc ttatcacgaa
    51661 aaggagtggt gcacgttgtt aacattatat acttccccaa gttgtacttc ctgcagaaag
    51721 gctcgtgcgt ggttgcaaga acatcagatt ccatttgttg aacgtaatat tttttcagaa
    51781 ccattgaaca gttctgaatt aaaagcgatt ttacaaatga cagaagacgg aacagaagaa
    51841 atcatctcga cacgttccaa agtattccaa aaactgaaca tggatttaga tgatctgccg
    51901 ttacaagaat tattggaact tgtgcaaaac aatcctggat tgcttcgccg tccaatcatg
    51961 attgatgata aacgtctgca agttggtttt aatgaagatg aaattcgtcg gttcctaccg
    52021 cgcgatgtac gacaattaga attacgtcaa gcacaattga tggctggatt atagaaggat
    52081 aatacgaaac ttggaaaaga
//
LOCUS       DAXLPY010000011        50729 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.011, whole genome shotgun sequence.
ACCESSION   DAXLPY010000011 DAXLPY010000000
VERSION     DAXLPY010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.011"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..1074
                     /locus_tag="ACF3UF_000753"
     CDS             <1..1074
                     /locus_tag="ACF3UF_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670904.1"
                     /translation="YVFEKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAF
                     SLLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGR
                     YNYKLSVFSIISLAELIFSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGK
                     PFFLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVN
                     GNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKT
                     SIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQK
                     NEFMQFGLTVLGICTFIITVINR"
     gene            complement(1314..1397)
                     /locus_tag="ACF3UF_000754"
     tRNA            complement(1314..1397)
                     /locus_tag="ACF3UF_000754"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1361..1363),aa:Leu,seq:gag)
     gene            1470..1631
                     /locus_tag="ACF3UF_000755"
     CDS             1470..1631
                     /locus_tag="ACF3UF_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670905.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            1780..2997
                     /locus_tag="ACF3UF_000756"
     CDS             1780..2997
                     /locus_tag="ACF3UF_000756"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD3670906.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3181..4017
                     /locus_tag="ACF3UF_000757"
     CDS             3181..4017
                     /locus_tag="ACF3UF_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3670907.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            4093..5241
                     /gene="nagA"
                     /locus_tag="ACF3UF_000758"
     CDS             4093..5241
                     /gene="nagA"
                     /locus_tag="ACF3UF_000758"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFD3670908.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            5519..6520
                     /locus_tag="ACF3UF_000759"
     CDS             5519..6520
                     /locus_tag="ACF3UF_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFD3670909.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            6539..7558
                     /locus_tag="ACF3UF_000760"
     CDS             6539..7558
                     /locus_tag="ACF3UF_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFD3670910.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(7660..8376)
                     /locus_tag="ACF3UF_000761"
     CDS             complement(7660..8376)
                     /locus_tag="ACF3UF_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3670911.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(8345..9130)
                     /locus_tag="ACF3UF_000762"
     CDS             complement(8345..9130)
                     /locus_tag="ACF3UF_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3670912.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(9121..9870)
                     /locus_tag="ACF3UF_000763"
     CDS             complement(9121..9870)
                     /locus_tag="ACF3UF_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFD3670913.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            10168..10692
                     /locus_tag="ACF3UF_000764"
     CDS             10168..10692
                     /locus_tag="ACF3UF_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFD3670914.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10708..12207
                     /locus_tag="ACF3UF_000765"
     CDS             10708..12207
                     /locus_tag="ACF3UF_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFD3670915.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(12295..12897)
                     /locus_tag="ACF3UF_000766"
     CDS             complement(12295..12897)
                     /locus_tag="ACF3UF_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFD3670916.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            13001..13957
                     /locus_tag="ACF3UF_000767"
     CDS             13001..13957
                     /locus_tag="ACF3UF_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFD3670917.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(14262..15218)
                     /locus_tag="ACF3UF_000768"
     CDS             complement(14262..15218)
                     /locus_tag="ACF3UF_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HFD3670918.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITINKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            15392..15952
                     /locus_tag="ACF3UF_000769"
     CDS             15392..15952
                     /locus_tag="ACF3UF_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670919.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15945..16769
                     /locus_tag="ACF3UF_000770"
     CDS             15945..16769
                     /locus_tag="ACF3UF_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFD3670920.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16779..17396
                     /locus_tag="ACF3UF_000771"
     CDS             16779..17396
                     /locus_tag="ACF3UF_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFD3670921.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            17414..18097
                     /locus_tag="ACF3UF_000772"
     CDS             17414..18097
                     /locus_tag="ACF3UF_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFD3670922.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18780..20063
                     /locus_tag="ACF3UF_000773"
     CDS             18780..20063
                     /locus_tag="ACF3UF_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3670923.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            20079..20966
                     /locus_tag="ACF3UF_000774"
     CDS             20079..20966
                     /locus_tag="ACF3UF_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3670924.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20983..21819
                     /locus_tag="ACF3UF_000775"
     CDS             20983..21819
                     /locus_tag="ACF3UF_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3670925.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21822..22445
                     /locus_tag="ACF3UF_000776"
     CDS             21822..22445
                     /locus_tag="ACF3UF_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670926.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            22442..23734
                     /locus_tag="ACF3UF_000777"
     CDS             22442..23734
                     /locus_tag="ACF3UF_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3670927.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGNVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      24093..24190
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            24306..24887
                     /locus_tag="ACF3UF_000778"
     CDS             24306..24887
                     /locus_tag="ACF3UF_000778"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFD3670928.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24890..26197
                     /locus_tag="ACF3UF_000779"
     CDS             24890..26197
                     /locus_tag="ACF3UF_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFD3670929.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26613..27101
                     /gene="purE"
                     /locus_tag="ACF3UF_000780"
     CDS             26613..27101
                     /gene="purE"
                     /locus_tag="ACF3UF_000780"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFD3670930.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            27094..28218
                     /gene="purK"
                     /locus_tag="ACF3UF_000781"
     CDS             27094..28218
                     /gene="purK"
                     /locus_tag="ACF3UF_000781"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFD3670931.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            28231..29526
                     /gene="purB"
                     /locus_tag="ACF3UF_000782"
     CDS             28231..29526
                     /gene="purB"
                     /locus_tag="ACF3UF_000782"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFD3670932.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29706..30083)
                     /locus_tag="ACF3UF_000783"
     CDS             complement(29706..30083)
                     /locus_tag="ACF3UF_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670933.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            30339..31067
                     /gene="purC"
                     /locus_tag="ACF3UF_000784"
     CDS             30339..31067
                     /gene="purC"
                     /locus_tag="ACF3UF_000784"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFD3670934.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            31067..31321
                     /gene="purS"
                     /locus_tag="ACF3UF_000785"
     CDS             31067..31321
                     /gene="purS"
                     /locus_tag="ACF3UF_000785"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFD3670935.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            31323..31994
                     /gene="purQ"
                     /locus_tag="ACF3UF_000786"
     CDS             31323..31994
                     /gene="purQ"
                     /locus_tag="ACF3UF_000786"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFD3670936.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31995..34217
                     /gene="purL"
                     /locus_tag="ACF3UF_000787"
     CDS             31995..34217
                     /gene="purL"
                     /locus_tag="ACF3UF_000787"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFD3670937.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            34202..35641
                     /gene="purF"
                     /locus_tag="ACF3UF_000788"
     CDS             34202..35641
                     /gene="purF"
                     /locus_tag="ACF3UF_000788"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFD3670938.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETNFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35664..36716
                     /gene="purM"
                     /locus_tag="ACF3UF_000789"
     CDS             35664..36716
                     /gene="purM"
                     /locus_tag="ACF3UF_000789"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFD3670939.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36713..37291
                     /gene="purN"
                     /locus_tag="ACF3UF_000790"
     CDS             36713..37291
                     /gene="purN"
                     /locus_tag="ACF3UF_000790"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFD3670940.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            37288..38823
                     /gene="purH"
                     /locus_tag="ACF3UF_000791"
     CDS             37288..38823
                     /gene="purH"
                     /locus_tag="ACF3UF_000791"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFD3670941.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38839..40113
                     /gene="purD"
                     /locus_tag="ACF3UF_000792"
     CDS             38839..40113
                     /gene="purD"
                     /locus_tag="ACF3UF_000792"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFD3670942.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            40235..41149
                     /locus_tag="ACF3UF_000793"
     CDS             40235..41149
                     /locus_tag="ACF3UF_000793"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFD3670943.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(41282..42847)
                     /locus_tag="ACF3UF_000794"
     CDS             complement(41282..42847)
                     /locus_tag="ACF3UF_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3670944.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42840..44291)
                     /locus_tag="ACF3UF_000795"
     CDS             complement(42840..44291)
                     /locus_tag="ACF3UF_000795"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3670945.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(44305..45321)
                     /locus_tag="ACF3UF_000796"
     CDS             complement(44305..45321)
                     /locus_tag="ACF3UF_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3670946.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45541..46629
                     /gene="chvE"
                     /locus_tag="ACF3UF_000797"
     CDS             45541..46629
                     /gene="chvE"
                     /locus_tag="ACF3UF_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD3670947.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46683..48209
                     /gene="mmsA"
                     /locus_tag="ACF3UF_000798"
     CDS             46683..48209
                     /gene="mmsA"
                     /locus_tag="ACF3UF_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3670948.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            48211..49416
                     /gene="mmsB"
                     /locus_tag="ACF3UF_000799"
     CDS             48211..49416
                     /gene="mmsB"
                     /locus_tag="ACF3UF_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFD3670949.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49673..50650
                     /gene="guaC"
                     /locus_tag="ACF3UF_000800"
     CDS             49673..50650
                     /gene="guaC"
                     /locus_tag="ACF3UF_000800"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFD3670950.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
BASE COUNT        16147 a         8645 c        11107 g        14830 t
ORIGIN      
        1 tatgtttttg agaaaataaa tgttaaaaat ttattattgg tttgctctat atactgttta
       61 ataccattga cagtaatggg ggaaaccggt tggagagcaa ccaccttgaa ctatcagtgg
      121 ccagtagcat ttagtttact aactttttat ccgttttttc aactcttaag aggagaagaa
      181 ataaatagaa aaatatattg ggtaagtatt cctttattga tatttttaac taatcaagaa
      241 caagtcaacg cctgtttttt tgttctaaca agtatagtta gtttatattt gattgtcaat
      301 ggacgatata attataagtt atcagtattt tcaataataa gcttagcaga attaattttc
      361 tctttgacaa ctccagggaa tgcattacgt gctgcacatg aaattaataa atggtttcct
      421 gaatataaaa atttcaactt tcttaataag ttagatttag gtatttcatc atttggaaag
      481 ccgttttttt tagacatgaa tatcttattt ttattgctat ttttcttaat tttccttcta
      541 acatatagga aatgtcaaaa ctattatgtg cgtatattga ctgcattacc gtttttctta
      601 aacctgatta tttattttgg taatacaatg ggtcaaagct ttacttacgt caatggaaat
      661 aaaagggcaa tgatttggag tagtagtaac ctgaataatc tctttacaga gttaggaacg
      721 aaactgtcac ttttttatcc aggtacttgg atagctactt tagtagtctt ggcattatta
      781 ctatgtttaa ttgttggaat ttatttaagt tttgacaata agaaaacttc tattttttta
      841 gttattttga tgataatggg attttgttca aggttaatta tgggattttc tcccacagta
      901 tgggcttccg gaatgcggac gtactatata ctttatgttg ttatcgccat cttagtacta
      961 atggcagtta aagagctaat gaaaagcatg agtgtacaaa aaaatgaatt tatgcaattt
     1021 ggattaaccg tgcttggtat ttgtaccttt ataataacgg tgataaacag ataatataca
     1081 aaaaatccct cgctttagta ttaggtgagg gattttactc gtttttcgat taattgtttt
     1141 aacacttgca agtttctacg agtagcttgt ttccgacctt catatactca cctcaggctg
     1201 tttacatgat tgtacgttct ttttgtaaag gatacagtga tatgtatata atggcataaa
     1261 gaaacgttca aacaaaaaaa ctcgtgaagc aaaattaact tcacgagttg tagtgcagat
     1321 gatgggactc gaacccacac gagctaacgc tcacatgacc ctcaatcatg cttgtctgcc
     1381 aattccaaca catctgcgta ataataacac actaatgata gcgaggtttt acatagttgt
     1441 caagctcaaa aatgggagga cttattaaga tggagaaata tgacggagaa ttttcaggac
     1501 tgggaatgat cttaggtgta ttgattggac ttgcattcgg acgttttttg cttggtttta
     1561 tgctaggaat catttgtgga attgcaatgg attgggcagc gaatctatgg aatgactatc
     1621 atgacaatta agttctcaac gcttgtttgt gtttttttaa tacttacgtt tttcctaaat
     1681 aagtggcaaa attttctagg atggagtatg atattgaaat agtaaataac aaaaaatttg
     1741 gaaagttcta actttttgaa atgagggatt ggctaagtga tgagagaatt tgaaaaatcc
     1801 aacaaattag aaggtgtcag ttacgatgtt cgcggtcccg ttctagaaga agcggagcgg
     1861 atgcaagaag agggcattag tattttaaaa ttgaacacgg gaaatcccgc accttttgga
     1921 tttgaagcac caaacgaagt cattcgtgat ttgatcatga atgcccgtga ctcagaaggc
     1981 tactcagatt ccaaggggat cttttctgct agaaaagcaa ttgagcaata ttgccaactg
     2041 aaacattttc cgaatgtgac gatcaatgat atctacaccg gcaacggagt gagcgaattg
     2101 atcacgatgt gtatgcaggg gttgctggac aatggagatg aagtactggt tccaatgccg
     2161 gactatccgt tgtggacggc ttctattgca ttagctggag gcacacctgt tcattatatt
     2221 tgcgatgaag aggcagaatg gtatcctgat attgatgata tcaaatcaaa aataacgagt
     2281 cggacaaaag ctattgttat cattaatcct aataatccta ctggggcact ttatccaaaa
     2341 gaattattag aagaaatcgt tgaagtagct cgacaaaata acctgattat ttattccgac
     2401 gaaatctatg atcgcttagt gatggatggt ctagaacata ttccgattgc tacattagcg
     2461 cctgatttgt tcgttgttac gctgaacggt ctatccaaat ctcatcgtgt agcaggattt
     2521 cgagtaggct ggatggtcct aagtggagat aagtcacacg tcaaaggcta tatagaaggg
     2581 ctgaatatgt tgtcctccat gcgtttgtgt tccaatgtat tgtctcagca aattatccaa
     2641 accgcgctag gcggttatca aagtgtcgat gagctgctcc tgccaggcgg aaggatctat
     2701 gaacaaagag aatatatcta taatgcaatc aatgatattc ctggtctttc agccgtaaaa
     2761 ccaaaagctg ctttttatat attcccaaaa attgatacaa agcgattcaa tattttggat
     2821 gatgaaaaat tcgttttgga ctttttacat gaacatcata ttctacttgt acatggtggt
     2881 ggatttaatt ggaaccagcc agatcatttt cgaatcgttt atcttcctaa aatggatgat
     2941 ttgaaacaaa cagctaagaa aatgagagaa ttcctagcaa cctatcgcca aaaatgattt
     3001 taaaaaccaa atttttcagt aggagggcca cagacaaaca cactgaggct ctctttctag
     3061 tggagttttc ttaaataact aaagtatatt atttagttgc aagtcttttc ttgaagtttg
     3121 cgacttccta aagtaaaata cgaatagaat gcgaatacgc atattttggg gaggatactt
     3181 atggaaacgt taatcgagtc ctttggaacg atcattaaag agattcgaaa agaacaaaaa
     3241 atgacgcaaa aaatgctttc gcatgatatt tgttcacaaa gtgtattaag tcggatcgaa
     3301 aataatgagg aactgccgaa tgtattggtg atgatgcaga tttgtcaacg gctaggggta
     3361 acgattgatc atgtgatgaa tctctctcga aaaactactc ggacaaacga taaattattt
     3421 gaactgttgg atagttgttt ccaaaaacgt gattatcgga agttagaaca agtactaaaa
     3481 tcttctgata tttctgaaaa tctgtatcaa gcaactgact ttcaacgcta ttattattat
     3541 ctcggtgttt gcgaattcac gttgcgtcaa aatatctctc agtcccttta ttatttgaaa
     3601 gaagcattaa gctactctag ccaaaaagaa agaatccatg tttctgacac agaaatacaa
     3661 ctgattagtt gtatcggaaa aatatatggt gtggcaggaa aaacggctga agcacgctac
     3721 tatttgagtc gaagcatcca actgctgcat caatcagctg atgaacgatc aaaaagtgaa
     3781 ttttcgcaaa ttttttataa ttatggaaat ttcttattcc atcaaaatga aatcgacgaa
     3841 gcgttagaac aggtgaatca aggaatctat tgggctcaag agaagaatag ctactattac
     3901 ctcaatgatt tatttgtgct taaaagctta atatacaagc gtaaagaaga accagaaaga
     3961 gcagcattct atgaaggctt agcacaagct gtgaaacaaa tttcaaaaaa tttgtaaatg
     4021 gtgtagacca ttcttgactt cttctctaaa taagagtact ttagaggtag aaaaacaaag
     4081 ggagagaata gaatgagaac ttttatctat gctgacaaat tctttttagc gtcaggtgtc
     4141 aaacatgcag gctatcttga aattaccgat ggactttttg gtgaatacac caaagaacta
     4201 cctgagggag aagtcaacat cattgaccaa agcggcaaat ggattgctcc tggtttggta
     4261 gatacacata ttcacggcta tatgaatcat gatgtaatgg ataatgatgc agaaggcatc
     4321 aaagtgatgt ctgaaggtct gttatcttgt ggagtgactt catttttacc aacaacattg
     4381 acgtcaagca aagaacgttt aaaagatgta gctgagacaa tcggcaaaat gtatcaggaa
     4441 gcaccaggag ctaaaatcaa aggaatctat tttgaaggtc ctttcttcac agaagaacac
     4501 aaaggggcac aaaacccaag ttatttcggg gatcctgatt tggatacttt ccatgaatgg
     4561 caagaagctt caggtggttt aatcaaaaaa attgctttag caccggaacg tcaaggtgta
     4621 gaagagtttg tcaaacaagt gactgaagaa ggagtagttg tttctctagg acacagtaat
     4681 gctacactag aagaagcgca aaaagctgtt gaagcaggcg caagtgtatt tgtccatgct
     4741 ttcaatggta tgcgtggatt gaatcatcgc gaaccaggta tggtgggtgc gttattatct
     4801 ttagaacatg tcttttctga attgatttgt gatggccatc atgtacatcc aaatgctgcg
     4861 ggaatcctaa tggaaaaagc aggacatgat catgtcgcat taattacaga ctgtatgatg
     4921 gccggtggga tgcctgatgg aaattacaat ttaggcgaat ttccagtagt agtaaaagaa
     4981 ggaacagcac gtctagaatc tggcaactta gctggaagta tattgaaatt gaaagaagca
     5041 attaaaaatg ttgtagactg gggattagca acaccagaac aagcagtcat gatggctagt
     5101 ctgattccag caatcagctg taaaatcgat gatacatgtg gaaaaatcgc tcaaggacgc
     5161 gatgcagact ttatcgtatt gaaccctgat atgacattgg aagcaactta tctagatggc
     5221 gtggaacgtt tccacgcata atataattta agttaacctt aaaactaaac ttcttaagtt
     5281 tggttttaag gttttttttg tgttctagta aaaatcactt tacataagtt tcaaaagttt
     5341 ctttaatttc ctattgttca ataagtaaca atgtaaagat aaaattaaaa atgttaatac
     5401 gtattagcaa aataaaagct ttttttattg tgaataaatg aacataatta ggaggagaaa
     5461 gatgaactta tttgacattt ttcgatcgac tttgacagat atgtcgattg tcagtgcaat
     5521 cacttcaaca gtttttatta tattattagg gtttgtttgt agaaaaaagg ggattttttc
     5581 tgaatctgtt ggaaaaattc tatcgaaagt cgtcttaaca gtggctttgc cagcactggc
     5641 atttcgagct ttcatgcaag atatcaatac agaattactg atgcaaggaa tcaatgtctt
     5701 gatttgggga ttagttattt atattattct tattctagtt tcaaaacctt ttttcttaag
     5761 ctataaaggg gataagcaaa caacgttgcg tgtcctgacg atctttggtt ctacgacctt
     5821 tttcggaacg cctatcgtca gtgcgattta tggtcctgtc ggcgtgatgt attcctcaat
     5881 tttcaatatt ggctaccgaa tctttttgta ttcttatgga tacataaaaa tgagtggctt
     5941 gaagatggaa gctaaaaata tcaaagcgat gttcgtcaat ccaatcatta tcgctacttt
     6001 tgccggcctt ttcatttggc tgttccaagg gtatctgcca caagtgtcag ttacaggtgc
     6061 agaaggagag ataagccaag tagcgttttt gcgaattgac cagactgcac cgtggctatt
     6121 tcagccgatg gattatttag ctggtttaag ttcaccattg gcgtggctag caatcggcgc
     6181 aacattaggt gaagtaagct tcaaaaaagc tgcatctgaa aaaacttcat ggtattacag
     6241 tctagtcaaa gtggtatttg tacctgcatt gaatatcgtg attctagcag ttttgacggc
     6301 aacgaatatt ctaccagtca attttgaagc actggcaaca atcgttatca tgatggctac
     6361 accagctgca acagtggcag cagcctatgc tatcagtttt gatagggagg cacttttagc
     6421 ctccaatgca tccttactgt caactatttt tgctgtggta ctgacacctg tatggatcgt
     6481 tgtattacaa atgattcatg gcataggttt attttcataa gaaatggagg aagaaagtat
     6541 gagaatcgca tgttacggtg ttcgtccgaa cgagatagat ttttttgaaa aattgaatat
     6601 ttaccattat gatctcagtc tttatgaaga actgttgaca catgacaata tcgtgtcagc
     6661 aaaggaccat gatgctgtat tgttgagggg aaattgtata gcagatgaga ccaatcttgc
     6721 aaaaatgcag gaatatggga ttcgttatgt ttttacacgg actgtgggag tcaatcatat
     6781 cgatctacaa gcggcagctg attttggtat gacagtagcc cgtgtaccat cgtattcgcc
     6841 aaatgcgata gcagagttat ctttgacttt tgccatgatg cttttgagaa atactgcgta
     6901 tacgacgatc cgaacatctt tcaaagattt tcgagtggat gagcaaatgt ttagtcgtga
     6961 aatcagaaat tgcacagtag ggatcatagg aacaggcagg atagggttga cggaagctgt
     7021 tttgtttaag ggactaggag ccaaagtgat cggctacgat attcatcaga cagaagctgc
     7081 taaaaaagta ttgacgttcc actcgcttga agagttatta gccaaaagcg atattgtcag
     7141 tattcatgta cctcatatcc caggtgaaaa cgatcaaatg atcaatgaag gatttttagc
     7201 tcaaatgaaa aaaggtagca tcttgattaa tacagcccgt ggagagcttc aagataatga
     7261 agctatttta agagctttga aaagcaatca tttagctggt tttgcaaccg atgtttttgc
     7321 aaatgaaaca gaggtttttt tccgatcctt caagccatgg gagacgattc cagaccctgc
     7381 tatccagcaa ttagtagaaa tgtaccctag agttcttgta accccgcatg taggttcaaa
     7441 tacagatgag gcattatcaa atatgatttc gacaagtttc gagaactttc gtgaaataat
     7501 agaaactgga aaaacgaaaa atgaggtatc tcttcctaaa gcccgtcaat taagataaga
     7561 aaacatggat attcgtcaat aaaatgttta aaaatagtcc aagtaaacag ttgttacttc
     7621 tgtatacttg gactattttg tatgggataa ttcgatgact caacagtaat ctgtgagctt
     7681 tttccgccca ttctttgtca attcataaca ggttagcggc cggccgattt ccaaatattt
     7741 gattctttcg ttcaatatat cttgttctac taaaaaattc aaatatttct tgacggatat
     7801 acgtgacagt gagctttttt gagccagttc ttttgttgaa aaaatagtat cttcttttag
     7861 aataaatgca cttatttttt ttaaagtcag ttttgacaga cctttaggca aatcgatgaa
     7921 tgatggtatt tcgtgaatgg gagtggtgtg gttgaatact tgatcgatca atttctgatc
     7981 ggctttttca gtcgtttgga ttgtctgaga gaaagcaaga tacttttcga tcgccagctg
     8041 aaaacgttgc aaagtgaacg gtttgatcaa ataatctaag gcaccgtagc ggatcacatt
     8101 ctttatggtt tcgatatcat ctgcagcagt gatcaaaatc actgggatat catttccttg
     8161 ctgtctaagc caagataaaa aatggatacc actttcgcca ggcatgtata catcaagcag
     8221 cagcagatct gcgttttttt gtctgaaata tttttttcct tcttctacat ttctgaaact
     8281 ttcgattacg ttcatattag ggatgctttc cacaaaagta cgattcaatt ctgcaaccat
     8341 tggatcatct tcgattatca ggacatttgt catcattttg atcttccttt tttggtaatt
     8401 ctagatagac gattgtaccg ccatttgttt gtttggaaaa ttctaaaaat ccaccgtggc
     8461 gtttgacgat tgaatggatg agattcaatc caaacccacg attgattccc ttcgtcgaaa
     8521 aacctagcgt aaatattttt tctgagattt cttctgatat cccgacaccg tcatcgcaga
     8581 cggtcacgat gaatacttca gcttctgtgt catagtttaa atgaatccgg acctgtccgt
     8641 ttctttcatg tttttgtagc acggcttctt ttgcattatc aagtaagttc cctaacactt
     8701 gcaaaagtga atggatggag tcatccatct ccattttagg gataaaagaa tcgctttcta
     8761 acagcatttc aacagattgt tctttggctt cgtttatttt gcctaataaa aaaccggcaa
     8821 ttgcaggtac tttgatcaga cttgagactt ggccaatctc ttttttataa ttttgattta
     8881 gctgctggat aaaatgggtg acttcttcat acttcttcaa atcaatcaaa ccagaaatga
     8941 catgaagttt attcatgaat tcatgggttt gagctctcat ggagtttata tattgtttcg
     9001 tccccccaag ctcctccatt aatttcatta cttctgatcg atttcgtaaa gttgcgactg
     9061 ctcctaaaaa acggtcattg ctaaaaagag gtgtaacgct agaaatagtt tctatcccat
     9121 ttaaatacat ggattgagtc cgaacggtcg tttgatgctc aatcgtctct ttaaacaaaa
     9181 cgtcatatag attatcactg atttttttcc tacttcgaaa tccaatagct gctctgtttg
     9241 gtagaaaatg ttttttgcag gtgtattgat caagaggata gttttatcag aagagatggc
     9301 taagattcct tcatctactt cattttcgat aatcgttttt tcacttaact gttctgctat
     9361 ttcttgtggt tcaagtccaa gcagtacttt tttcattttt tgggcaagaa aaacggcgcc
     9421 tatgatgcct acgctaagtc caataatcaa tgaaaaaaca atcatttttt gtccatcttt
     9481 gacttgattg tcaatcgtgt tgtttgttaa gccaacacaa actgcaccaa taatctcttg
     9541 atcataataa atagggacga aatagcggaa gccgaaccct aacattcctt ctttttcaga
     9601 gaaaaattct tgtcctccaa tcactttttt cacatcttca tgacttgaga aaggaagacc
     9661 gatgtaactt gggtctgcgt gagaatatcg aatgccttca gggtccatga caacgataaa
     9721 atctaaattc gatgcaatca tgatttcatt tgttattcct tgaatcgcat gtgtcgggtc
     9781 accagtctgc agcttttttt ggatgagttt atcattggca acgattttag caatgctaga
     9841 gattttatct gacacactag atcggttcat cgaaagaata aaattcctga tcaatatggc
     9901 agaaacaatc aaagaaacga atgtggagaa acaaacgaca aggatgatcg tgttctggag
     9961 ctttaatggt tttttcttaa aaaaaggaaa cataggctac ctcgaaagaa tttattgtga
    10021 aaattttaac atgaaaacaa aaatttaaca aattgtcaac gataaacaca accttcctat
    10081 aaaaaacacc actgagtcgg taaaagaagc tatacagaat tttcaaacat tggtatgata
    10141 gacgtagaaa tggaaggagg cgtgtatatg atagggggaa tcgcacttga gacgatttat
    10201 tggtatacat tgctgatttg tgcaggattg gcagtcctat tgattatttt tggagatgta
    10261 ttcgattttg atggcccgct tgatccgatg cttattatcc cttggttaac tttcacaagc
    10321 ttatttggtt ttctaggtga gcgtttaaca gatcaatcat ctttattttt atttattgct
    10381 agtggaggca tatcgatagt gttggtattt ttgcttaatt tctatatatt gatgccgatg
    10441 aaacatgccg aatcaacgat gtcgtcttct gaaaaaactc tggaaggaca agtagctgtt
    10501 gtgatcacac cgatccctgt acgaggtatg ggagaaattc agttgaaaag tgttaccggt
    10561 tccattagtc gtccagcttg tttttacagc ccccaagaac agacagctga gcggggaacg
    10621 aaagtattga tcattgagat caaggaaaga atctgttatg tcatgcctta tgaaagcatg
    10681 ataaaagctt aaaggagcgt gtgttaaatg gaaataccag ttgtttttat cgcgatcgca
    10741 atcgcagctt tgattttact gatgttgctg atcgtctttg tagcgaagta ccagacagca
    10801 aaaccggatg aagcgttgat catcagtgga agttatttag gaagcaaaaa tgtgcacatt
    10861 gatgaaagca ataacaaaat caaaattgtg cgtggaggtg gcgcattcgt cttgccagtt
    10921 tttcaacgtt cgaatcggat cagtctatta tcgagtaaat tggacgtctc cacccctgaa
    10981 gtgtatacgg aacaaggcgt accggtgatg tgtgatggta cttcgatcat caaaatcggt
    11041 tcatctgtag aagagattgc tacagcagca gaacagtttt taggcaagac aagagaagaa
    11101 ctggaaaatg aagcaagaga agtattagaa ggacacttgc gctcgattct tggttctatg
    11161 actgtagaag aaatctatca aaatcgcgat aagttcagtc aaagcgtaca agaagtcgct
    11221 tctgtagacc ttgcaaaaat ggggttgatc atcgtttctt tcactatcaa agaggtcaga
    11281 gacaaaaacg gttatcttga ctctttaggg aaaccaagaa tcgcccaagt caaaagagat
    11341 gcagatatag cagaagcgga agctctaaaa gaaacgcgta tcaaaaaagc tcaagcagaa
    11401 aaagaatcac aagcagctga attacagcga caaacagaga tcgcagaatc attaaaagaa
    11461 aaagaactga aattagcaac ctacaaacaa gaacaagatg ttgctaaagc aaaagcagac
    11521 caagcctaca atttagaaag tgcccgagca caacaacaag taatcgaaca ggaaatgcag
    11581 attaaaatcg tagaacgtca aaaacaaatc gaactggaag aaaaagaaat cacacgtcgt
    11641 gaaaagcaat atgattcgga agtgaagaaa aaagcagatg ccgatcggta cgctaaagaa
    11701 caagaagcac aagctcaaaa agtcaaagaa gtgactgaag ccgaagcaga acgattccgt
    11761 gtggaagcac tggcagaagc ggaagccaat aagacacgtt tagctggaca agcagaagcc
    11821 gaagcagcac tagcaaaagg aaaagcagaa gccgaagcaa aacaaaagat cgccaatgcc
    11881 ttcaaggaat atggcgaagc agctgtcttg agtatggtta tcgatatgct accgcaattg
    11941 atgcgcgaag cagcacagcc gctaggaaat atcgaaaaaa tctctgttgt cgatacagga
    12001 agcagttcag gagaaaccag tggagcgaac cgagtgacaa attatgccac aaatttgctt
    12061 tcttctactc aagaaacact aaaagcgaca acaggacttg acttgaagga aatcgtagag
    12121 aatttgtcga cacgtgggac tactagccaa gtaaatatgt atgaagcgcc aaaagaggca
    12181 gaacaaaact cgatgaagga agaataaagt agtacacttc accgttcaat caaaaatgga
    12241 ggaagacttt ttaaagttct tctctccatt tttttatttt attgcaaaag aaaattagtc
    12301 ctcgctattt ttcttttgtt tttggatctt agcttctatc tcttgtaaat ttgttcttag
    12361 caatcgttct ttcttttgga gttcgaccaa atcttctgat agttcttcct tcttttctgt
    12421 ttcaggagga cgaagaaaga aattgatacc gattgcaatg aatgtcccta taaaagtatc
    12481 tagtacacgt tggatagcat acaaagcgga ttcgccttga gggatgctca acgcaatcag
    12541 caacaacgta gctattgcgg aaatgatacc ggaattattg ttaataccat ctgacacgac
    12601 gatcacaata ataactagaa taggaagcaa gatcaattct accaaaaaat cattgtgaaa
    12661 atagcttttg acaaaaaaat aaatgatagc taatgtacca cctaatgtat tgccgatgat
    12721 cctagacttt ccaaaagaaa cggttgtagt caagtcctga cgcaaagaaa aaacagcaga
    12781 taatgcagca atcatcggga ttcctcgttg agtcaaatga aaaaacaaga tacataaaaa
    12841 aacagctaag gcacttttga tcgtacgcat acctagtcga aaacggccaa attgcataga
    12901 gattctcctt tttggtcttt ttactatcat acctaaactt ttgtctgata gctagttttt
    12961 cattattcaa gtataattaa aataaaaaag ggggaagtaa atgcgtatag gaatgcgaac
    13021 agtcaaaaca gtgatcagtg tcttcttttc gatggtcaca gcgggtagct tatcgctgtt
    13081 gtattggcca gctgcaggga tcattgcatt attaagtgta ggaaatacca agcgctctac
    13141 attgcgtacg ggcatgaatc gaatcgcagc ctttatatta gctacggcaa cagcactgtt
    13201 cagttttttt gctgttgggt atactatttt tggcttcagt ctttttttat tcctgttcat
    13261 cccgcttgcc tctcgcttca aattaaccga agggatagta gtaaattcgg ttttggtcac
    13321 tcattattta gtggaggaaa acatgtcttg gcagctgatc ggcaatgaag cgggattaat
    13381 ggcgattgga ttagtatttg ctttgcttgc aaatgtttac atgccagatc gtacgaagca
    13441 gctgaaggaa aaccaaatac agatcgaaaa agaatttcga aatattttga gacaaatggc
    13501 agaatttctt ttatcagaaa ataaagaaga tgtgcagatc aaatgcgaac atttactgac
    13561 attcattcgc gaaagccaag aagatgccag agaacatcaa gaaaactact ggctcagaca
    13621 gccgctatac tacgaaactt acttctctat gagaagagca caggccaatg tgattaaaga
    13681 catgctggaa aatctagaga gaatccagca accagcttat tatggaaaac atatctatgg
    13741 tttattgatt tatactgcag aaacattttc agagtcaaat gatggcagac aaattttaac
    13801 acgtattgaa gaagtttatg tattgtatcg gcaaatgcct ctgccgacta gtcgccctga
    13861 attcgaggat cgagcagaat tgttccagtt tttgcagtct tttaaaagtt ttattgaaat
    13921 caaggcagaa ttctcccaac aaaaaatcca aaaatagagg ttgtgaattc agctaatatt
    13981 caggtcaaaa agctgatttc acaacctctt ctttaaacgg tgttctcctg tcaactcctc
    14041 ggtcacaagt cacaatattc aacaaacatg agaagctgtt ttttgaaatt gctccttgtg
    14101 actcggagct gaacggtagg ctcacaacct ctttcttaaa cggtgttcaa aagctttcct
    14161 ctgcggtaat aagtccagcc aaacgaaaaa taggaggagc tatttttgtt tggctgttct
    14221 tattacttga tgcagaacag ctttttcaca accttttaaa attacatatt tttccataga
    14281 acttgcattt gatccaagat ttcgatgaca tcttttgtca agaagagaga gcgattgggc
    14341 aagtcacctt caatcatgtg taccatattc tttatttcgt aattcattgc ttcagatgta
    14401 ttcccgcttt cgatgaattc ctttgtacca tctgtaaata agatctccgc acgatcagca
    14461 cgcgggtaat cagcaatcgt cacataaccg ttctcaaagg caacgatacc gacttttggc
    14521 atttttgcct gaaaagtcaa gctgacagca gcaagttcat tttctttgtt acgcaagata
    14581 gtgacggatt gttcgtccac gcctgtttca aaaggaacca ttgtagaggc aactacttca
    14641 ggttgagagc tcaaaaagaa acgagcgaaa gatacagcat acgtaccgat atccaacaga
    14701 gctcctccag ctaattctgg attgaagaac cggtttttag ggtctggttc tttgtaactg
    14761 ccgaaaggtg cttggatcat ttttaaagcc cccagttttc ctgtatccat tattgagcgt
    14821 aactgctgat aaagtggcat gttgaagatt gtcatcgctt ctgctaagat caaattcttt
    14881 tcttctgcta agcgcatagc gtcagccagt tcttttttat ttatcgtgat ggctttttca
    14941 catagaacgt gtttgcctgc ttccaatgct gccaagatat ggtcgatatg ctgtctattt
    15001 ggtacagcaa tgtacacgat gtcgatttca gcatcgtcta acatttcttg atagcttccg
    15061 taagcttttg gaatattgta acggtgagcg aagttttccg ctttttctga agttctggaa
    15121 gcaactgctg ttagttcgct cgtctcttga ttgaagcttt cggcaaactc atgtgcgatg
    15181 gtaccaagac caacgattcc ccattgatat tttttcatct gaaaacgctc cttcatagtt
    15241 ggattgagtt tcttgtctgt ctattattat aacaaaaatc acgaagaata aagaggagag
    15301 gacttgaaac attaaaaaaa atgaaagcag cgatttaaga ggtgcttttt gatcaaaact
    15361 taagtagaat agttaaaagg aggggataaa cgtgcatcaa gtatatattg atcttattat
    15421 gagtgtatta ttagaacagt ttgaaactga aaaaaatttt ttagatgaat acttgctgat
    15481 cagtccagaa caatggcaaa aatggaaaga tggcgagaaa aatctgccat ctgaagcgat
    15541 gcagaaagta aaaaatcttt tcactgatta tgaatggatg ctaacgcaaa agattttgcg
    15601 tcaaacgatt atttttcccg aaaaacgaaa cgttgccgtt gcagagtaca agcaaatcaa
    15661 aacacgcatc gcgcaaaaat ggcttagcag caaagcagca aaagtcgagc tgatcccttt
    15721 gaaaaataat cagcaggctg gtagatacct tgacttgaaa gtaagtattc aatatgatga
    15781 atggggctat gatgatattt tgaattttcg tctgccagca gatgttcaaa aacagatcga
    15841 aggagaaaaa atcgaacttc tcgattgggt gaatgaaaat ctggaagaaa cttacgttca
    15901 tgaggcgaat ggggaacgtg aagaacaacg aaaggatttt tcaagtgaat aaatttttag
    15961 gatttggagc agttgtgatt atgatcgcag caatgggcta tgttattttt agcgatgatg
    16021 attcgcatgt tcaagccggc aatcaagcag tcgaacgaac aagcaccaaa acaactgcta
    16081 gtaaagaaaa gaacagtcaa acaaccagca gcaaggtaaa ggacaaagaa acaaaagatc
    16141 gtacgtccaa acaattgcca gatgttaaaa cagacgattg gaagctagtt ttggttggtc
    16201 cagatcacaa attagaaaaa gaaattgatg agtctactca attggcatca ttaagtaacg
    16261 gatacttgat cgacaaacgc attgctccag aatatgaagc atttgccaag gctgctgaag
    16321 cagctggatt tccattagtg atggtctcag cttaccggtc tgtatcatcc caacaacaag
    16381 ttttcgaaca aaatgtccaa gatgtgatga gtcgtcaagg tgtatcagaa gaggaggcga
    16441 caaagattac taaagaaacg attacggagc caggatacag cgaacaccac acaggtctgg
    16501 cagtcgatgt cgtcgatcaa aactggtaca acagttatcc ttctactgta ttggatgcaa
    16561 gttacggaga tcagcctgga gctaaatgga tcgcagataa tgctgcgcag tatggattta
    16621 tcgttcgtta tccaaaagga cacgaagata taactaagat cacatatgaa ccttggcact
    16681 tacgttatgt cggtaaagaa aacgctgagt atatcaccaa acaccaattg acgctagaag
    16741 aatatctgaa tgaattaaat gaaaagtagg aattgatcat ggcgaaaaaa aagtggaaaa
    16801 agcaaaagcg caagaatatc cgttggccag cagtggttgc cggtgtagca gtgatactct
    16861 tagcctttgt tttttccttg aagaatctgt cttctccttt tactgataat cagcaagaaa
    16921 atgaagcgca atcccatcag caatttattg aacggcttgt tccgcatgcc caagaactac
    16981 aagatggtta tggagtgctt cctagtatca ttttaggaca agctatatta gaatcaaatt
    17041 ggggaaaaag taccttggct agcaaataca ataatctttt cgggatcaag gcttatgggg
    17101 atcagaagaa agtaagcctg gaaacaaagg aatttgttaa cgaagaatgg ataactatcc
    17161 aaggagactt caaagtgtat gattcatggg aacagtccat ggatgaccat acacaactgt
    17221 tcgtccaagg agtagattgg aatcctgcgc tgtatgaaaa agtgattacg gccaccaact
    17281 atcaggaagc cgcacaagca ttgcaagatg caggttatgc gacagacccc ggttatgcgc
    17341 aaaaaatcat ccaggtcatc gagacgtatc aattgaatca gtatgaccgg agatagcaaa
    17401 ggagaagtgg ctgatggcag aacaatttac gccagaaatc atgacggaat tgagaaaaga
    17461 tatcgtaaga gtaccggaaa tcattttaga agcaagcggg atcaagatat ttggaaaatt
    17521 gatccgttcg atcatcttta ctacggatat tgcgatcata cgtaatacaa atgcgaatgc
    17581 agtaattgct gtgtatcctt ttacacctca tccagcgatt actaaaagca ttattgaggc
    17641 agctgacatt ccagttttct ccggtgtagg tggtggtttg acacaaggtg ctcgttcttc
    17701 ctacatgagc atgttcgcag aagcgcaagg ttcgttaggg gtcgttttga acggtcctac
    17761 gcctttagag acagtaaaag aagtttgtcg agtagttgat attccagtta tcagtacggt
    17821 aacgtcgaaa tatacagaaa tagatgaaaa gttagcagct ggtatttcga ttatcaatat
    17881 cagtgcaggt aaagaaactg cagaagcagt acgccatttt cgtaaaaaat atcctgaact
    17941 tcctatcatt gcgacaggtg gtccaacgga agaaagtatt gctgagacca ttcaagcagg
    18001 agcaaatgcc atcacatata cgccaccaag tagcggagag ctttttagtc gtaaaatgga
    18061 aaaatatcgg gaaactgaga aaaagaatca tgaataacag gtgagaatca aaagacgagg
    18121 aagagcagat agtggctctt cctcgtcttt tgtactccag tactatttgt tcagaattca
    18181 aaaaaaagag aaattttttt gtttttttac ctgtaatgta cataagaaga gttaaaacct
    18241 tttgttatta ttagcattct aacaaaaaaa tgtcttgatt tattgaagcg ctttctatag
    18301 aatgaaaaac gaataaaaac taaaaaaggc acccgacaat ttagtagcag ctaaattgtc
    18361 ggggcttgaa aagtcagcgg gaactgacca atcaagttgc catagtcaat gcttgtgcat
    18421 cgacgtgtat attgtaccta atttcataca gaattactag ttatttttct gttttttagg
    18481 gaagagcgca cacgaagaag catgcttatt tagctatgtc aaggatattg ggcagttgtc
    18541 tgatatcctt ttttctttgc gtaattatcc tcccatcatt gaagcaagaa gtgtttttag
    18601 cgatgaaaga agaatcagca ctatctaatt tttcttgaaa gtattgagtt gttcatccta
    18661 ggcagaacga taaggcaagt cttggttttt attccccttg aaaaagatcg tttaataaat
    18721 atgttctgta taaaaataca gtatattgaa aaataacaat ggaagtagag gtgcagagaa
    18781 tgaagaaaag aatgagaatc atcttagctt taagtgttat gttattcttc ttgacggctt
    18841 gtgggcaaga agatgacaaa aaaatcacgc tgaacatggc ttggtggggt tcgcaagtcc
    18901 gacacgatgc aacagtaaaa gtaatcgagc tttatgaaga aaaaaatccc catgtgacga
    18961 tcgattatga attttatgat tatgaaggat attacacaaa attaggtaca ctagcagcat
    19021 cagatgatat ctgggacatt ttccaactga acaatcaatt tcctcaatac atcaatcaga
    19081 ttgaaccatt agatgaatat gtggagcaag ggataattga tatttctaat gcagatgaat
    19141 cctatttagc aacgacgact tacgacgggc aattagttgg actgtctaac ggggtgaatt
    19201 cgtttgcgat tgcttacaat aaaaatatat ttgaacaatt aaatatccct gaaccagctt
    19261 caaattggac atgggatgaa tttgaacaaa tcagctatca aatcactgaa gaattaggaa
    19321 tctatgctat ttcaagattc gaagatttta tagctggctg tattattcaa ataccacaag
    19381 ttgagaaagg attgaatttt tataatcggg aagatctatc taacagcttg ggatttgaaa
    19441 atccagacta tctaacagat tttttccagc tgcgtaaaaa tctggtagac aaaggggccc
    19501 atccagaacc aggtggtgga gctgcaagta cgacggatct gtcttttcag gcggttaggg
    19561 atagagaagc ggcaatggtg tttctatcaa gtaaccagtt gacagaaata ttgtcagggg
    19621 ctcctgaaga tatggagatt cagttgatta atccacctcg cagaaaagca gatggagaat
    19681 ctggtatccc tttacgttct tcgcaaatgc tgagtatggc aaaaagctca gcccataaag
    19741 aagaagctgc taagtttatt gatttctttc aaaacagtga agaagccaat gaaattttaa
    19801 aaggagaacg tggtgtacca atcatgtcga atattcgaga acagctcgct cgtgcagatg
    19861 atgcaacttt gcaagcgaca tttgattatt tagaaatgat ttccgatatg gacaacggcg
    19921 aagtgaatgt ctttgatagt gctttgaatc cggaaattca agaccaatac aatcttttag
    19981 ttgaaaaagt catttatgaa gaagtaacag cagaagaagc agcagagagt ctttatgagt
    20041 ttgcgtcaaa cattctagga tagcagcagg aggaaggcat gaaaaaagaa aaactaaaac
    20101 ggttcttgga tcaagacaat gtggtcggtt acgtatttgc ttctccattc atcctaggat
    20161 ttctattgat aacagtgata ccgatgatct tgtcacttta ttattcgttc accgattatc
    20221 gtttgggaaa tccagtctca tggatcggct tggataatta tataaagatg ctgagtgatg
    20281 cccgtttttt gaactccatc cgagtcactt ttctctatgt atttgcatct gtacctgtga
    20341 aactgatctt tggtctattg attgcttatc ttttaacgag gaatatcaaa ggaacgactt
    20401 tctttcgttc tttgtattat gtgcctagtt tgatcggtgg cagtatttct atcgctctag
    20461 tttggcggga gttgttttct aaaaacgggt tagtgaatat tttcctggaa cgattaggcg
    20521 cacctgcgct ttcctggttt agcgatcaaa aactggtcat gatccctctt gttttgatgt
    20581 ctgcttggca attcggttcg gcaatgatca tctttgctgc aggtatcaaa gagatcccag
    20641 gctcgtatta tgaagcggca gagatcgatg gagcgaacaa atggcagacg ttttacaaga
    20701 tcacgttacc tcttctttcg ccgatcattt tgtataactt ggttatgcag acaatcgcgg
    20761 cgtttatgac ttttacgcag gcatttatca ttacccaagg tggtccgaat gatgccacga
    20821 acttttatgc tctttatgtg tataaccaag ctttttcttt taattctatg gggtatgcta
    20881 gtgctatttc gtggatcatg ctgttgatta tgggagctgt cacctttctg attttcaaat
    20941 catcaaaaaa atgggtcgtt gtgtgaatga gaggaggaag aaatgaataa tacagtaacg
    21001 aaatggtttc aatacggttt tattttgcta ttaggtctag tcatgattta tccggtctta
    21061 tggatgatcg caggttcttt taaaacggat caagagatta tgagtggttc gctgaatttg
    21121 attccagaga cttttcaatg ggaaaattac gcaaaaggat gggcggggtt tgctggaatt
    21181 tcatttttta ctttctttag gaattcgttt gtcatctctg cagtttcgac gatagggaca
    21241 gttctgagct cgacttgtat tgcttacgca ttatcgagaa tcgatttcaa aggaaaaaga
    21301 ttctggttcg tcgtcatgtt agtaacgatg atgattcctg cacaagtgat tttgattccg
    21361 cagtttatta tttacaatcg gctgaatttg gttgggacgt atgtgccgct gattttacca
    21421 catttttttg gacaagcatt tttcatttac cagatcatgc aattcatggt cagcatcccc
    21481 aaagagttag atgaatcagc gattattgac ggatgcagca agtatagtgt ctttaccaaa
    21541 attatttttc ctttgctgaa accttcgatc atcacgacga tcatcatcca gttttattgg
    21601 aaatgggacg acttcatggg accattgatt tatttaaaca agccgagatc ttacacggta
    21661 tcgattgcca tcaaattatt tgcagacgct ggatctagta cgacttacgc gagtatgttt
    21721 gcgatgtcta cgttgtcgct gctaccggtt tttctgattt tcttattctt caataaatat
    21781 cttgtccagg ggatcagtac aagcggtctg aagggctgaa tatgaaaaag ccaatagaag
    21841 agatgtttct ttacaagctc aactactatg tctgtcggat ttttttaacc agtcttatca
    21901 gtaatgctct tttcgcttta gttctaggat gtttgttcac tttaggatta gtgctgtctg
    21961 ctcgtgttgt ctatctgatt tattttttga tgatgtatcc ttcttattat ctatctgtcc
    22021 attacttggc agaaaaaaag gtatgttgga ggaaaggaaa aatcaaacgg atgtgtttca
    22081 tcattacgtt gtttcagctg tttgtcatta tttttgcagt tgattggtat ttattagtgg
    22141 gaaagattgg agcttggtat ctgattcctt ttctattgtg tctgttgctt tttgtatccc
    22201 atagtttttt tagtacgcta attgatatct gcaaagaaga taaagcagat agtcttgttt
    22261 atttgatcaa aaggaatatc tggctgttgt caaaaaacgt caaggggttt ctgtggtatt
    22321 tatgcctttt gtatggactg ttctggtgta tacagcatga ttttttactc actgcattac
    22381 tgtatccagg gctgccattt gtcacagtat tttgcttaaa agaaaaggag aatgacttta
    22441 aatgaagaaa aaatatgtac aagtcggact tggtgggaga gcgcgttttt tttatgaggc
    22501 aattgcctct acgtatcatc aaacttgtga actagtcggt ttttgtgatg tatctcaaac
    22561 aaggatggat tatgcaaatc ggatacttgt gaacaagtat ggacagaaaa aagtaaagac
    22621 atgtatgcca tcacaatttg agcaactact ggatgacgta cggccggctg aagtcattat
    22681 tacgtcagta gatcgaacgc atcatgatta tatcattcgt gcaatgaaaa aaggatatga
    22741 tgttatttgc gaaaaacctc tgactatcga tgaggaaaaa gctcaagaaa taataacggt
    22801 ccaaaaacag acgggaagaa gcctgcgagt cacttttaat tatcgttatg caccgtatca
    22861 cacgaagata aaggaactga tagaaagtga tgtgattggt aatgtgtttt ctatccactt
    22921 cgaatggctg ttaaatacgc aacacggggc agattatttc agaagatggc atcgaaataa
    22981 gcacaatagc ggcgggcttc ttgttcataa atctacccat cattttgatc tagtgaattt
    23041 ttggttgaac agccgtcccc aaaaggtatt tgcattcggt ggattaaact tttatgggat
    23101 gcataatgcg gagaaacgcg gagtagaaat attttacagt cgatgctatg gaagcgaact
    23161 agctaaagct gatccatttg ctatagacct gtcagccaat gaggaattgc gagaaatgta
    23221 tttagaagca gaaaaagaca gtggatatat tcgtgaccgc agtgtatttt ccgatgatat
    23281 ctctattgaa gatacactag gcgtaacggt caaatatgaa actggtgcga ttttgacgta
    23341 ttcgctaaac gcgtatatgc cgtgggaagg attcaatgtt tctttcaatg gcagcaaagg
    23401 acggatcgaa atgaaagtga tcgaaaagtc ttacatcaat gcaggtggag ataaaaagga
    23461 tgaaggagca gccgttcttc agtccatcca tgtctatccg atgttcggtg agccatatga
    23521 ggtaatcgtc gaacaagaag cgggcggaca tggcggagga gatccgcgtt tattagatga
    23581 tctatttggt gaagaaaaag aagaagatcc gtggaatcgg gcagcaactc acgtagatgg
    23641 tattttgtcg attttgacag gaatcgcagc aaatcattct attgcttcag gaaaagcagt
    23701 agtgattgac gagcttgtca gcttaaaaga ataagaatag atttacggaa attacttccc
    23761 gtagtttata aaatcttgcc ttattgccga taggctgtct tttgaacact atttattcgg
    23821 aaaaaggggc tatgacatgc tttttgtcat gccttctttt tatgtgggct gcttttttag
    23881 ataggagaaa ataaaaataa ctatttaaac ccgaacaaaa aggaataatg cattaaaaat
    23941 cattagattt tacaaaaaaa taagtaaacc acgttgtcag tttcagaaag tagtgttaga
    24001 ctgttttcaa tatttgaaac aacatttttt attcaaatat ggcaaactgc cttcacgtgc
    24061 aaaacagttg caagaaaatg aatttacact attattagtt ttacatacct acttatatat
    24121 cgtcataata tggatgacag tttctagcca gtaccgtaaa tgctggacta taagtaaaag
    24181 attggctatt tcacccttct tttcttatga taaagtggag ggtgtttttc tttaacagaa
    24241 acatagtagg tttttgcaca aaagcggtta tttcggtatt aataaatgat aaaggagcaa
    24301 ataaagtgaa agaattagtt gaacgtattc aaaaagacgg acgtatatta ggcgagggcg
    24361 tattaaaagt cgacagcttc gtcactcacc aagtagaccc tgtattgatg gaacaaatgg
    24421 gaaaacggtt tgcagaagta tttaaagaac aaggaatcac gaaagttgtg accattgaag
    24481 cttctgggat cgcaccagct ttatttgctg caagagaatt agatgttcca atgatcttcg
    24541 ctagaaaagc aaaaagtttg acgatggatg aagaattatt gacagcttct gtttattctt
    24601 ttacgaaaca agtgacaagt acgatttcta tttctcgtaa atttttatct tcagaagaca
    24661 aagtattgat tatcgacgat ttcttggcaa acggacaagc ggcaaaagga ttgatcgaat
    24721 tatgccagca agctggagcg caagtagaag gaatcgggat cgtcatcgaa aagtctttcc
    24781 aagatggacg tcagttactt gaagaaatgg gattgagagt cgtttctctt gcgcgtattg
    24841 cttccttgac gaatggacaa gttgagtttc ttgaggagga cgcataatcg tggaaaaaga
    24901 aacacaaaat ggaaaagctg cggttttagg gctgcagcat ctgctagcga tgtatgcagg
    24961 agcagtagcg gtgcctcttt tgatcggtac aggactaggc tttaatcaag aacagatgac
    25021 ttatttgatt tcaattgata tctttatgtg tggattagcg acattattgc aattgacagt
    25081 taaccgattt ttcggaattg gcttgcctgt cgttttagga tgtgcgatcc aagcagtagc
    25141 tccactgatc ttgatcggaa ccaatgaagg agtaggagct atctacggat ctattatcgc
    25201 ttctgggatc tttgttgtgt tagtttctgg tgtcttttct aaaattaaaa aactattccc
    25261 tcctatagta acaggaacgg ttatcaccgt tattggtttg actttgattc ctgtagcaat
    25321 cgagaaaatg ggtggaggta atgcaacagc agctgatttt ggtgacaaaa caaatctgct
    25381 acttgcattt gtgacgattc tcctaattgt aggcgtgcaa atgctggcaa aagggttcat
    25441 tcgttcaatc gcggtattga ttggtttagt cggaggaagc atcttagctg ctttcatggg
    25501 aatgattgat ctgagcgcga ttggagatgc gccgttgttc catgttccac aaccctttta
    25561 ttttggtaaa ccaactttcg acgtatggtc gattttacta atgatcatca tttccatggt
    25621 cagcatggta gaatcaacag gtgtatattt tgcacttggt gacattactg ggaaaaatgt
    25681 tggagaagaa gaattgaaaa agggatatcg tgcagaagga cttgccgtta tcttaggcgg
    25741 tattttcaat acattccctt atactggctt ttctcaaaat gtcggattgg ttcaactttc
    25801 gggaatcaaa acaagaaaac ccatctattt ctctgcattc ttcttgattg ttttaggatt
    25861 attccctaaa atcggtgcgt tagcacaaat catccctgag ccggtacttg gtggaggaat
    25921 gttagtcatg ttcgggatgg tggcagtcca aggaatccgt atgctgttgg aagttgattt
    25981 cagcaatgat aaaaatctat tgattgttgc tgtttctgtt ggatttgggc tgggtttcaa
    26041 tgttacgccg acattattca gtcaaatgcc gcaaacattg caaatgttca ctggaaatgg
    26101 catcgtaatg agtagcatta cggctatcat attgaatttg atctttaatg gattgaaaaa
    26161 agatgaagaa atattggaag aagccttcaa gaagtaatag agcaaaagaa aggttgtgaa
    26221 atcagcgttt tgacctgatt gttagagaaa caaacggaaa aatagttcct cgtattttgc
    26281 cgtttgtttg agctaatacc gagggtcagc tgattgaaca ccgttgaagg aagaggtcgt
    26341 gagcctgccg ttcatctccg agtcacaagg aacaatttca aaaaaaagct tctcatgttt
    26401 gttgaatatt gttccttgtg accgaggagt tggcaggaga acaccgttta tccataaaaa
    26461 ggaatgtgac ctaacttttg tcacattcct tttttttatc tttaataaac acgaacaata
    26521 aaatgttttt ctttgttaac attcgaaatt tctttgacat caaaaaaagt gattgttaaa
    26581 atatgaatgt agaaaaactg ggaggaaaaa caatgacagc aaaaatctct gtgattatgg
    26641 ggagtacttc agattgggaa acaatgaaag aagcatgtca aatattggat gaattcggtg
    26701 tgtcttatga aaaaaaggtc gtttctgctc atcgaacccc agatttgatg tttgaatatg
    26761 cacaaaacgc tcgaaaaaaa ggaatcaaaa tcattattgc aggagcaggg ggagccgcgc
    26821 atctgccggg tatggtcgca tcaaaaacaa ctttgccggt tatcggtgta ccggtccaat
    26881 cacgaacatt aaatggtttg gattcgcttc tttcgattgt ccaaatgcct ggaggagtac
    26941 ctgtagctac tacagcaatc ggaaaagcgg gagcaattaa tgctggacta cttgcgatac
    27001 agatgctttc catgtatgat ttagaattgg aggctaaatt ggctgaaaga cgttcaatgt
    27061 tggctaaaac tgttatagaa agtagtgatc aacttggtta aacctttgtt gcctggttca
    27121 acgatcggga tcgtcggtgg cggtcaatta ggtcgtatga tggcgattag tgcaaaagaa
    27181 atgggcttta aagtaggtgt gctggatcct gtgagcgatt gtccagccgc acaagttgca
    27241 gattggcata ttgaaagtgt ctatgatgac acctttgcgc tgaaagagct tgccagaaga
    27301 acagatgtca ttacctatga attcgaaaac gtcagtgtag aggcgttaaa tgcgatttta
    27361 cccatgtcat ttattcctca agggacagac ttgcttgcga ttacgcaaga ccgcctgtta
    27421 gaaaaatctt ttttggaaac gaataacatc gtgattgctc cttatgcaac gatcgtcagt
    27481 ccgacggata tccaagatgc gattgacggg atcggctatc cttgtgtttt gaaaaccact
    27541 cgaggcggct atgatggcaa ggggcagtat gttttgaaaa gtcgggcgga tctagctcct
    27601 gccatggacc ttttaagaga aggaacctgt gttttagaag catggatccc gtttgaaaaa
    27661 gagatttcga tcatggtggc aggaaatggt caaggagatt tcacgacttt tccggtcgtg
    27721 gaaaacatcc accacaacaa tattcttcat gaaacgattg ctccagccgc gattgatcag
    27781 gatgtgatcg aggaggctga gcgtattgcc cgtgtgattg cagaagcagt gagcctttca
    27841 ggtgttttag gggtagaaat gtttttaaca aaaacaggcg ggctatatgt gaatgaatta
    27901 gctcctcgtc ctcacaattc tggacattat tctattgaag cttgttctat gagtcagttc
    27961 gatgcccata ttcgaggtat ttgtggttgg ccattaggag aaaaagtacg tttgataagc
    28021 aatgcagtaa tggtcaatgt tttgggagaa caactgctgg aaagctatcg cttgattgag
    28081 aataagccag actggcaatt ccatttctat ggaaaaaaac aagcaaaaaa aggtcgcaag
    28141 atgggacata tcactatctt gacagaagac atccagcaaa cgctggaaga aatcaaacaa
    28201 acgaatattt gggattagag gagaaaaaac atgttagaac gttatacacg ccctgaaatg
    28261 gggaatatct ggacggaaga gaacaaatac cgtgcgtggc tcgaagtcga gattttagca
    28321 gatgaagctt gggcagaact tggtgaaatc ccgcaagaag atgtgaaaaa aattcgtgag
    28381 catgcatcat ttgatatcga tcggatcttg gaaatcgaaa aattaacacg ccatgatgtc
    28441 gttgcgttta cacgagcggt ttctgaaaca ttgggagaag aaagaaaatg ggtccattat
    28501 ggtctaacaa gtacggatgt cgtagatact gcttatggct atctcatcaa gcaagcaaat
    28561 gatattttac gggaagactt gaaacgtttt acggaaatca ttggcgaaaa agcaaaagaa
    28621 cacaaatata cagtgatgat gggtcggaca cacggtgtcc atgctgaacc aactactttt
    28681 ggattgaaac ttgccacatg gtattcagaa atgaaacgga acatcgaacg atttgaacat
    28741 gcggcaaaag gagtagaagc aggaaaaatc tcaggagcag tgggaacgtt cgcaaatatc
    28801 ccgccattta ttgaagagta tgtatgtaaa caattgggga tccgtccaca agaaatttct
    28861 actcaagttc tccctcggga tctacatgct gaatatttct cagcgatggc gcttattgct
    28921 acaagtattg aacgttttgc aacagagata cgcggattgc aaaaatccga aacacgtgaa
    28981 gtagaagaat tttttgcgaa aggtcaaaaa ggttcttctg ctatgccgca caaaaggaat
    29041 ccgatcggtt cagaaaatat ggctggtcta gccagagtgg tgcgcggaca catggtcact
    29101 gcctatgaaa atgtcacatt atggcatgaa agagatattt ctcattcttc agcagaacga
    29161 atcatcttgc ctgataccac gattttattg aattacatgt taaatcgttt tggcaatatc
    29221 gttaaaaatc taacggtctt tcctgaaaac atgaagcgga atatgtctgc aacatttggt
    29281 ttgatttata gccagcgcgt tatgctgaaa ttgatcgata agggaatgac aagagaagaa
    29341 gcttatgatc ttgttcagcc aaaaactgcg tacgcttggg acaaccaagt gcagttccgc
    29401 ccgctgttag aagaagatcc aaccatcaca tcggtattat ctaaagaaga aatagacgat
    29461 gcctttgatt atcatcatca tttgaaaaac gttgacgtga tattcaaacg agtaggtttg
    29521 gaataaagaa gagtgagttg caaaattcaa ttaaaataga atagcaaaaa taaccaaaaa
    29581 agaagcagat ccgttagcgg ttctgcttct tttagtttat tatattttct tatcaataat
    29641 aggaacctga ttttaaaagc ggctacctct ttaccgtgcc tctttacata caaaaaatag
    29701 aggaattaag cgtaaatggc ttggctatta taactaaaat gctggttatg gagatgttgc
    29761 agcaagtttt cgagaaaagc gtattccatc tcttgtccat tgaataagat ctggatacga
    29821 taatgatttt tgaaacgctt ctgttcatga atctgactga ttgaaagttc gcctttgtgt
    29881 tctgtctgat aaagaaaagt ccttttacgg cattcagcac agcgtttggt tgctcggcgg
    29941 atttttcgga atgtataaaa actagtatct ttattgcata aataaacgtc tttgatcgac
    30001 agcaaatcat tatatagaca ggaacgttct tcagctgtta attctgataa aaaaagctga
    30061 ccttgtttta ttgcatcttc catcggcaag tgcctcctcg aacccattat ccaaattttt
    30121 agttaattct aatataccat cattaagtat aaatgtaaac gcttgttgat ggtataagat
    30181 tttcgtttct gataaaacac gaacattaaa agaatctaat gccttaaatg tacatatttt
    30241 tgttgattta taaaaagatg attgctaaaa tttaaagtga aaaaacgaac aaaaaacgat
    30301 gtatttgctt ttaatgtaaa taaaaaggag agacgtacat ggagaagaaa gaacttttgt
    30361 atgaaggaaa agccaaaaaa atatatctta cttctgatga gaacttgatt tggatagaat
    30421 atttagatca agcaactgcg ttgaatggcg cgaggaaaga ccagataagt ggaaaaggag
    30481 aattgaataa tcaaatcaca agtgcaattt tccgttatct gactcaaaga ggaataaaaa
    30541 atcattttat tgaacaattg tctaaaaccg aacaattagc aaaaaaagta caaattatcc
    30601 ctctggaagt ggttatccga aatattgcag caggaagttt ctcaaaacgt ctaggtgttc
    30661 ccgaaggtaa agaattcatc aaaccaatca ttgaattcta ctataaggat gaccagttgg
    30721 atgatccatt tatcaatgaa gagcatatct atttcttaca acttgcaaag ccggaagaaa
    30781 tcagtgagct gaaagcccaa gcgttggcta ttaatgaaat tttgaccgaa ttatttgcta
    30841 aggtcggttt ggttttagta gatttcaagc tagaatttgg ccggtcgaat ggacaaattt
    30901 tgcttgcgga tgaagtaaca ccggatactt gccgattatg ggatgaacgt acgaatgaac
    30961 atatggacaa agacgtttac cgcagagatc taggtgattt gatcccagtc tatcaagaag
    31021 tatataaccg tctatcggaa ctaactgaag aaaaggagcg agtatgatgt atttcgtaaa
    31081 agtatatgta acctataaag attcagtgtt agatcctcaa ggggaggcag taaaaaaagc
    31141 agtccatcgt atgggatatg aaacaatcga agatatccga ataggaaaat actttgagat
    31201 acaacttgct gatgcagaag aaccaatcga tacagtgatt gaaacgattt gtgacaagct
    31261 gcttgcaaat gtaaatatgg aaacataccg atatgaaatc aaaaaaatgg aggaagtata
    31321 acatgaaatt tgcggtcatc gtttttccag gttcaaattg tgacgcagat atgttatggg
    31381 cagttcgcga gatcatgggc gctgatgccg aatttgtacg gcatgatgag tcctctttag
    31441 aaggatttga tggggtttta ctgccgggag gattctccta tggtgactat ttgagatgcg
    31501 gtgcgattgc tcggttttct acaatcatgg aagaagtgat tcgttttgct gaagaaggga
    31561 aaccagtatt cggtacatgc aatggattcc agatattgac agaagcagga cttttgccag
    31621 gtgtactgag acgaaatgag tctttgcatt ttatttgcaa aactgtacca ttgaaagtca
    31681 accccaagac ggcctttact tcagagtatg aagccgacga aataatctat cttccagttg
    31741 ctcatgggga aggaaattat ttctgtgacg aagaaacact tcaagaacta aaaaaaaata
    31801 atcagattgc ctttacttat aatgacaaca tcaacggcag cgtggaaaac attgcaggga
    31861 ttacgaacaa agcagggaat gtgttaggaa tgatgcctca tccagaacgt gcagtagaag
    31921 acttgctagg atcagaagat gggaaacggt tctttgcttc cattttaaaa aacttcggaa
    31981 aggtgaccgt atagatgaaa acattgaaag aaccgacagc tgaagagatc aagaaaaaaa
    32041 gaatctatgc cgaatgggga ttgactgatg aagaatatcg aatgatcgaa gaagatatct
    32101 taggaagaat gcctaattat acggaaactg gactgttttc tgttatgtgg agcgaacatt
    32161 gttcctataa aaattctaaa ccggttctac gcaaatttcc tactagtgga cctcatgtgt
    32221 tgcaaggccc tggagaaggc gcaggcatcg tcgacatcgg tgatggacta gcagttgtct
    32281 tcaaagcaga aagtcacaat catccttcag ccgtggagcc ttatgaagga gctgcgacag
    32341 gagttggcgg aatcatcaga gatattttca gcatgggggc tcgtccaatt gcgttgctag
    32401 attcattgag gttcggcgaa ttagataatc caagaacgaa atatttacta gaagaagtag
    32461 ttgcaggtat cggcggatac ggcaattgta tcggcatacc gactgtaggc ggcgaaattg
    32521 catttgatcc ttgttatgaa ggaaacccat tagtcaatgc aatgtgcgta ggtttgattg
    32581 aacacaaaca tatccagaaa gggcaagccg ctggcgtcgg taattcgatc atgtatgtag
    32641 gtgcaaaaac aggtcgcgac ggtatccacg gagcaacttt tgcctcagaa gaatttaatc
    32701 aagaagaaga acagcaacgt tctgctgtac aagtaggcga tccttttatg gaaaagctgc
    32761 tgcttgaagc gtgtttggaa ttaatcttgc atcattcgga ttctctaata ggtatacagg
    32821 atatgggagc agcaggactt gtttcatcta gtgcggaaat ggcttcaaaa gctggctcag
    32881 gacttatatt gacattagat gaagtcccac aaagagaaac tgggatgaca ccttatgaaa
    32941 tgatgttatc ggaatcacaa gaacggatgt tgatttgtgt taaatcagga gaggaagaaa
    33001 aaatccaaga actatttcag aagtatgatc tagatgcagt cactatcggt aaagtaacag
    33061 acgacgggca atatcggcta tatcatcaag gagaagaagt agcaaatctg ccagtcgatg
    33121 cattagctga agatgcacca gtttatcata aagaaatgaa agaaccagct cgaatcgtag
    33181 aatttcagca gttagctcct tatcagccag ttatcgaaga acctggacaa gtattgcttg
    33241 atctgctgca gcaaccgacg attgcttcaa aacgttcaat ctacgaaact tatgattcac
    33301 aagtacaaac caatacagtt gtccgtccag gaagcgatgc tgctgtgatg agggttagag
    33361 ggacgaataa agcgttagct atgaccacag actgcaacgc gcgctatctg tatttggatc
    33421 caaaaatcgg aggacaaata gcagtggcag aagctgctag aaatattatt gctagcggtg
    33481 gtaagccctt ggcgatcacc gactgcctga actatggttc tcctgataaa ccagaagttt
    33541 tttgggaatt atcgacttca gctgacggaa ttgctgctgc gtgtgaaacg ttaggaactc
    33601 ctgttatttc aggaaatgtc tctttatata atgaaacgga tggtcaagca atctatccaa
    33661 caccaatgat tggtatggtc ggattgattg aggatcataa acatatcact actcaggaat
    33721 tcaaaaaatc aggggatcta atctatatat taggtaagac gtttgcagat tttgatggca
    33781 gtgaattaca aaagatgcag cttggaagaa tcgaaggtgt gatccgaaac tttgatctat
    33841 ccattgaaaa gagaaaccaa gagttagtat tgacagccat ccaaaacgga ttgattgaaa
    33901 gtgctcatga ctgttcagaa ggtggcttgg caattgcact ggcagaatca gctttcaaac
    33961 atcagctagg gatatctgta cagtttgaat tgtcctctgc tcaattattt gcagaaactc
    34021 aatcaagatt tgtgttgaca gtcgcaccgg aaaataagac acgattcgaa gaaatgatgg
    34081 gagatgctgc tgttttagca ggtaaggtga cggatgaagc gataatcgaa atttcagcaa
    34141 ctgacggtca gatcaaaata gaaactgcag tagcaagaaa gtgctgggag gatgcaatcg
    34201 tatgtcttat gaagtgaaga gtttaaatga agaatgcggg atcttcggtg tttggggtca
    34261 tccagacgcc gctagtgtgg catacttcgg gctccatagt cttcagcatc gaggacaaga
    34321 aggtgcaggt atcgtgtcca atgatcgagg aaagcttaag gggcatcgag atttggggct
    34381 gctttctgag gtattcaaag atcaaagaaa attgcagcag ttaacaggag aagctgcaat
    34441 cggacatgta cgttatgcaa cagcaggcaa tggaagtgtg gacaatattc agccttttct
    34501 attcaaattt catgatcagt cgatcggctt agcgcataat ggtaacttga tcaatgctcg
    34561 ttcccttaga aaagagttag aggaaaatgg ggcgatcttc cattctaact ccgatacgga
    34621 gatattgatg catttgatcc gacgaagtga agaaacaaat tttttaaata aattaaaaag
    34681 tgctttgaat gaagtcaaag gtggctttgc ctatttatta atgacagaaa cggcaatgat
    34741 tgccgctttg gacccaaatg gttttcgtcc attagcaatc ggacaaatga aaaacggagc
    34801 atacgtgatt gcctcggaaa cttgtgcatt agaagttatt ggggcacgtt ttataagaga
    34861 tgtccagcct ggtgagatag tgatcatcaa tgacgaagga atccagattg attgctttac
    34921 gaaggacacg cagctttcta tttgttcgat ggaatatatc tattttgcca gaccagattc
    34981 aaacatcgca gggatcaatg tgcatactgc acggaaaaat atgggacgga atttagcgaa
    35041 agaatcgcca gtaaaagcag atatggtcgt tggcgtacct aattcttctt tgtcagccgc
    35101 aagcggttat gcggaagcta gtggaatccc ttatgaaatc ggattagtaa aaaatcaata
    35161 cattgcccga acatttatcc agccaacgcc tgagctaaga gagcaaggtg ttcgaatgaa
    35221 attatctgct gtacgaggag tagtggaagg taaaaaggtg attatggtcg atgattcaat
    35281 tgttcggggt acgacaagca gacggatcgt ccatcttttg aaagaagcag gggcaaaaga
    35341 agtccatgtg aggattgctt ctcctccttt gaaatatcca tgtttttacg ggattgatat
    35401 tcaaacgcgt aaagaactca ttgcggcaaa tcacacgatt gatgaaatca aagaatgtat
    35461 cggtgcagat tctttaggtt ttttaagtga agagggtctg atcgaatcga tcggtctgga
    35521 aaaagatgct ccgtattcag gattgtgtat ggcttatttc aacggagatt atccgacgcc
    35581 gttatatgac tatgaagaaa aatatcagga atcactaaaa gaaaaagtat cgttctttta
    35641 aaagcagacc aagaagggag tatatgaatt caatggcaaa tgcatacgca aaagctggcg
    35701 tagatgtcga agctggatat gaagtagtag aacggatcaa gaagcatgtc aaaaaaacgg
    35761 aacgtttagg tatgatgggc gctataggag gattcggcgg ttgttttgat ttatcggtct
    35821 ttcaattaaa agagccagtc cttgtctcgg ggaccgatgg cgtggggacg aaattagcag
    35881 tggcaatcga agcagacaaa cacgatacaa tcgggatcga ctgcgtagcg atgtgtgtca
    35941 atgatatctt agcacaaggc gcagagccgt tatatttctt agactactta gcaacgggga
    36001 aaaatgatcc gttacgtttg gaaaatgtag taaaaggtgt agcagatgga tgtgttcaag
    36061 gaaatatggc gctgattggc ggagaaacag ctgaaatgcc tggtatgtac tcaggtaatg
    36121 attatgatct agccggattt gctgtaggga tagctgaaaa atctcaatta ttgacaggag
    36181 aaacgatcaa cccaggagat gtgttgcttg gaatagcatc tagcgggatt cattcaaatg
    36241 ggtactctct tgttcgcaaa attttctttg agcagcagca gttttcttta tcatcaaaac
    36301 tgccagaatt gaaaaaaaca cttggcgaag aattgcttga gccaacgaaa atctatgttt
    36361 cttccttgct tccgctgatc aaagaaaaga aaataaaagg agctgcacat atcactggtg
    36421 gagggtttgt agaaaatatc ccgcgaatgt taccagaatc tatggctgca caaatcaaac
    36481 ttggctcatg gccgattctt ccaatattcg gctgtttaca aaaatatggt gaaattcctg
    36541 agatggagat gtatgaaatc ttcaatatgg gcatcggtat ggtcctggca gtcgaagaat
    36601 cgaaagtaaa agaaatagta cacgaaattg agcaagctgg cgaaaaagtt tatgaaatcg
    36661 ggaaagtgat cgccaaagaa aaacatcgtg tggtgtttat aggagaagaa cgatgagaat
    36721 cgctgttttt gcttctggaa acggaagcaa ctttcaagcg ctagccgatt atctatcgaa
    36781 aaaaggattg gaatcttcga ttgactggtt gttttgtgat cagcctgaag catatgtttt
    36841 gaaacgtgca actgcgttga gtgtaccggc agattgtttt tcacctaaag aatttgattc
    36901 aaaaaaagag tatgaagaag caattttgca taaattgaaa gaaaaaaaga tcgatttgat
    36961 cgtattagct ggatatatgc gaatcattgg accggtattg ctgaaaaatt atgataaaag
    37021 aatcatcaat atccatccgt ctcttttacc tgccttccct ggtttgcatg gcatacgtga
    37081 tgcctttgaa gctggagtaa aagaaacggg tgtcacaatt cattatatcg accaaggtgt
    37141 agatactgga ccaatcatcc ggcaggaaaa agtgagaatt gaacaggagg acacgttcga
    37201 ttctttagaa gaaaaaatcc atagagtaga gcatcgaatc tatccagaag tgattagtga
    37261 aattattgaa aatggaggct atctgaaatg acaagagcat tgatcagtgt atcagataaa
    37321 actgggattg tagcattcgc ccaaggtttg attgaacaag gagtagaaat catttcaaca
    37381 ggaggaacaa agcatgcgtt ggataaagct gggatcaaaa cgctttcgat cgaagaagtg
    37441 acagggtttc ctgaaatgat ggatggccgt gtcaaaacac ttcatcctaa aatccatggt
    37501 ggtcttttag gaagacgcga tctccctagc catatggagg caatggaaac ggaaaatatc
    37561 caaccaatcg actttgtttg tgtcaattta tatcctttca aagaaacgat tatgaaacca
    37621 gatgtcgaaa tagcagaagc tattgaaaac attgatatcg gtggtcctag tatgctccgt
    37681 agtgcagcaa aaaaccatga atttgtcacc tctgttgttg atccatctga ctatgaagaa
    37741 gtactttcag aattacgtca gtatgggcat acttcacttt ctttcagaca aaaactagcg
    37801 gcaaaagtct ttcgtcatac tgcggcatat gatgcactga tcgctcaata cttaacggat
    37861 tgggtggaag aaaaagaacc ggaaaaattg acacttacgt atgaacgaaa acaaacgctt
    37921 cgttacggtg aaaatagcca tcaagccgct gccttttatc agtccgctct tctggaaaaa
    37981 tattcgatcg cagcagcaaa acaactccat gggaaagaac tttcttataa taatatccga
    38041 gatgcagatg ctgcgctacg gatcatgaag gaatatgacg agccaacggt agtcgccttg
    38101 aaacacatga atccttgtgg tattgggaca gcatctacga ttttagaagc gtgggaagca
    38161 gcgtatgaag cagatcctgt ttcaatcttt ggtgggatca tcgttttgaa tcgagaagta
    38221 gatctgccaa cagcagaaca gatgcataag ctgtttctag aaatcatcat tgccccttct
    38281 tatacacaag aagctttgga attactgcaa aaaaagaaaa acatccgatt actgacagta
    38341 gactttgcgc aggaagaaaa tcaaaatcga gaagaaacgg tctcagtctt aggtggactt
    38401 cttgtacaag atcaagatct ggcaatagaa aatgaagaag agtggaaagt cgtgacaaaa
    38461 cgtaagccga ctccagcaga agcaaaagca ttagtgtttg cttggagagc tgtcaaacat
    38521 gtgaaatcta atgcgatcgt actggcaaac gaacgtcaga cagtaggaat cggagccggg
    38581 cagatgaatc gagtcggttc agtaaaaatt gcgattgaac aagcgcaaga gaaaatggaa
    38641 ggtgcagttt tagctagcga tgcttatttt ccaatggatg attcggttga atatgcagcc
    38701 aaacatggta taaaagcaat cattcagcca ggaggaagca tcaaagacca agattctatt
    38761 gatatggcga ataaatacga tctagcaatg gtctttactg atgttcggca ttttagacat
    38821 tagagaggag tcggataaat gaacattttg gtgatcggtg caggtggtcg tgaacatgca
    38881 ataagtaaaa aacttttagc cagtccgaag gtggatacgg tgtattgtgc gccaggaaat
    38941 ccggggatga caaaagatgg tatcaattgt gtcgctatca gtgagcgaga tcattcagcg
    39001 ttaatccatt ttgttaagaa agaggctatt gattggagta tcgttggtcc tgaagttcct
    39061 ttgttaaatg ggatcgtcga tgattttatg gcggaaggat tgaaaatctt cggtccgaca
    39121 aaagcagcag ctctgatcga aggttcgaaa agttttgcta aacaattaat ggatacttat
    39181 caaatcccga cagctaaatc cagaagtttt gaatgttacg aaaaagcagc agcgtatatc
    39241 aaagaaaatg gtgcgccaat cgtagtgaaa gcggacggct tagcagctgg gaaaggtgta
    39301 gtcgtggcta ccacagtgaa ggaagcgctg gatgcggcag aacaaatgtt gaaccagcat
    39361 cgatttgggg atagtagcaa aaaaatcgtc gtagaagagt ttttggcagg agaagaattc
    39421 tcccttttgg cgtttgtccg taataccaag gtgtatccga tggtcatttc gcaagatcat
    39481 aagcgggcat ttgataacga taaagggcca aatacaggcg gaatgggtgc ttattcacca
    39541 gtaccgcaaa tttcaaaaaa gatgattgaa aaagctgtgg aagaagtttt aaaaccagcg
    39601 gctttgggaa tgaaagaact aggacgctct ttcacgggtg ttttatatgc gggtttgatt
    39661 gctacgaagg aaggaccaaa agtgatcgaa ttcaatgcgc gtttcggtga tcctgaaacg
    39721 caagtcgttc tttctcggtt gaagagtgac tttgcgcaag taatcgatga tttattagag
    39781 aatcgtacag tagagttaaa gtggcagcaa gaaggataca atgtaggcgt tgtggttgca
    39841 gctgccggtt accccgaaga atatgagaca ggaatggttc taccagattt tctggaagaa
    39901 gagctttctg tttactatgc tggagtttcc tcaaataacg gcaaactagt tggagcagga
    39961 ggacgtcttt atttagtaga agcatacggt gagacgatca aagaagcaca gaaaaaaatt
    40021 tacaccgcgt taatggataa aacgacagat ggaacatttt atcgtacaga tattggagaa
    40081 aaagctgcca atagcgaact gatcgtgaag taaatcagct gcttccattt ataaaaaata
    40141 caacaaacat aatcggaagc gccgatttta gtgaagcctt ttcataaaga gtgtggtaca
    40201 cttttgttgt gtatataaat aaggaggagt tcagatgaaa aaaattcaat taggtacttc
    40261 tgatcagaaa gcagctgcag tgatcttagg ctgtatgcgt atcaacaatg cggaagatcc
    40321 agtaaaagtg attgagacag cttatgaaaa cggcattgat ttttttgacc atgcagatat
    40381 ttatggaaac ggtgaatgtg aagaaatctt tgcagatgct ctagcaaaaa catcaatcaa
    40441 acgagaagat ctttttattc aaacaaaatg tggaatcgtt ccaggtgtga tgtttgattt
    40501 ttctaaaaaa catatcattg aatctgtaga aaaaagtttg acccgtctga aaatggatta
    40561 tgtggatgct ttacttcttc atcgtccaga tacattggta gaaccagagg aagtagctga
    40621 agcgtttgat gaattggaac ggtcaggaaa agttcgttat tttggcgtca gcaatcaaaa
    40681 accaatgcaa atcgaattgc tgaaaaaata tgttcgtcaa ccattagtag ctaatcagct
    40741 gcaatttggc ttgaaacata ctggaatgat cgatcaaggg attcatgtca atatgacaga
    40801 tgaagcaagt atcgatcatg acggtagtgt acttgattat tcccgattgc atgatatgac
    40861 gatccaagca tggtcaccat accagtatgg attttttgaa ggtgtattta tcgggaacga
    40921 aaaattccct gaattaaacc aaacattaga agaactagca gctaaatatc aaacgacacc
    40981 aactggcttg gcttctgctt ggattttacg ccatccagcc aatatgcaag tgatcgccgg
    41041 tacgatgaac gtagggcgaa tcaaggaaat cgctcaagct tcagaaatta atatgtctcg
    41101 ggaagattgg tacgaattgt accgtgctgc tggaaacatt ttaccttaaa gattgtcata
    41161 agcaggtcaa aagggctata aattaaaaag acagaataac ttgaaagctg ttttcagctt
    41221 cgagatattc tgtctttttt tattgcaaat ggaaagagta tcattgtacg gatttcgttt
    41281 attagttatt tttgttttta aggaaaagct gtgtccgata ttcttttgga gaaatccctt
    41341 gttttttctt aaataaataa ctgaaatagt tagggtcatt ataaccaatt tcaaaagcaa
    41401 tatctgaaat acgatagtct gattgctgca ataatttttt tgctaattcg attctttgtt
    41461 ctgtcagata atcgatgaat gtttggttaa acgattgaga aaaaatcgta ctgaaatgag
    41521 agggacttaa tgcaacttgt tgagcgaccc aagttaagga catatctgga tcggtaaaat
    41581 tttctttgat aaaatccaat gcatggttca aaattggctg atatttgttc cttgaaggct
    41641 gtgagggcag agcagttaag aaagaaatga acatataaac tgtcgaacgg taaagcgagt
    41701 cgtcggcgct gattgctaag cgttgactgg tggatgtgca atgaaccatt tcttgcggga
    41761 ttttcttttc tttcaggcag acatgctgga gtagcttagt caagacaaat aaacgatata
    41821 atcgtgttcg agttggtgtg ccttgtggtt tcgtcaagtg ttcgatgtac ttagatactt
    41881 cgtttttcga taatgaagac aaatcaagtg agaggtcaaa gtaaaagaca gaatcaactg
    41941 gaagtttcgc ttcttgaatc aaatcctcat agctgataat ttgttcttta agggaactgg
    42001 cggtttcaag tatcatctgc gtgatctcaa aagatgcagg taattcgctg attctttctg
    42061 cgacaggacc aatggcgaca gaaaaattat ttttttgtcc cttttctaat tcatggacca
    42121 acgtttgggc tacctgataa ctggtctcga tcacattttc ttcaagagaa tcaactatta
    42181 aaaatttgat gaatcgagag gaaacagcag agaagatcac ttgttgattc tccctaaata
    42241 aaaacttcaa ataatcactg agatgagcgt aatcttcaaa gtctgtactg acttggtttg
    42301 ctgctaataa tacggtcatt tttttccctg ctaaagagcg attgaaagat tcagcaagtt
    42361 tcaatgtttc actgatcgta agtgagcctt tgaacaaacc gttcaagaaa tgattttttt
    42421 tcaattcgaa aacaagatca gaagaagtgt gcgtttcttt ttgctgcaaa tctaaagcag
    42481 ttactgcttt ttctattgct tgtttcaatt cgctactttt aatcggttta agcagataat
    42541 catctgcctg tacctggatt gctcctttca tataatcgaa atcgtcgaat ccactaataa
    42601 atatgagacg agtccaagga agtagtttcc ttgcttcttt tgaaaaagtc aacccgtcca
    42661 tgaaaggcat ttggatatca gtcagaatga tgtcgggctg taagtcgata attgaagaca
    42721 gtgccatctc accatctcca gcttcgccga cataagtgat tggataataa gaaccaagga
    42781 cagttatttg ttcccgcaag ttattgcgaa tgaggtattc gtcttcgatg ataaaaactt
    42841 tatacatgtt tgtttcctcc aattgttttg ggagatagag ggatcatcag tgtgacagtt
    42901 gttccttctc ggtatttgct gtcaatcgtg ataggttttt gatcatttcc gtaataaaga
    42961 aggagacgct tgtttacgtt gtaaagtccg tagccgatac tgaaatctga atcgatccct
    43021 ttggctaact ctttacgtat ttctgccagt ttttctgcag ggatgccaat cccgttgtct
    43081 ataactttga attggatcat ctcatcaatt ttgcatgtgg taatacgaat aaatcctttg
    43141 tgacggacgt acttcgttcc atggtataca gcattttcaa tcaatggctg caagatcatt
    43201 tttaaaatag aaacaggaaa aagtgtttct ggtatatcga tcttatagtc aagcatatgg
    43261 ccgtatctta tttttaagat gactagataa tcattgatat ggctaatttc tttttcaaga
    43321 ggaatccagt cttgtccttt gcttaaagac gtacgaaaaa agccggaaag tgcatgggtc
    43381 atagtcagag cttcttcaaa gcagtcttgt tcgatcaaag aaataatggc atccaaactg
    43441 ttataaataa aatggggagt aatctgagct tgcaatacac gaacttcact ttgtgctaaa
    43501 tggtattgtt tcaaagcgtt ctcccgtaaa gactggttta gatcttccgc cattttattc
    43561 atgctagcgg taagtgtttg taattccagt gtttccggca gggttaaacg aaagccaagg
    43621 ttccctgaag aaagttgttc tgacatctcg atcagctgat tgatcggttc ttggaccttt
    43681 ctctctaaaa agcgacgatt ctttttcgca tagaaaaaaa tggtactaag aactccaagt
    43741 tccactattg ttaatagaat gagcgagcgg acaagtgtcg tatttttttt gcttgctaag
    43801 tcgatctcca cacgaacaaa atcttgtaag atatctgaca gcagttgagt gacagaatct
    43861 acctgattga tgatctcttc attggtatcc ataaaatctt ttgccaagat attattgatc
    43921 agctcgtttt gataatcttc cagtgtatcg atcgtacgta gcgatacatc taacgtacta
    43981 atttctttaa gtgtatttgt attatttttg ctctctcgaa tatcattcct aagttcttct
    44041 aggatatttt cctcattgaa ctcatctacg gttacttggc cagaaatcaa gtcccacata
    44101 ctttccaaaa ctttttgatc aaccttcaaa gcaattgcat ctgctttttg gatatttgcg
    44161 atcgtctgtt gataaatcaa aagctgttgc gaatataaca gtatgctcag tagcaaaggg
    44221 ataacagcaa atagaagcat ggctttgttt gcttgggcaa aaatctgttt tatgcttaaa
    44281 ttttttgtca tgatacttct ccagtcaata atttctggtt gggatgttag ctatattctg
    44341 ctgggaaaag acagtctcgg aaataaaaat atctttaggt aatgtttttc ctgtttgaat
    44401 atttccaaaa taacgagtaa cggtattggc tacataccag ccgacatcag gtttacactc
    44461 gactacacaa ttgacgattc ctgagcgtag cttctcgatc atatcttctt gtccatcaat
    44521 agttacaatg atcaaatctt ctccaggttt gattgatgtt tcttttatcg cagctaaagc
    44581 accgtgagtc atttcatcac tatggctgta taatacatcg atttcggata aatcatttgt
    44641 ttctaaatat cgtttcatct ggtcttttcc tttcatccga ataaaatcac cgacaattcg
    44701 gtgaacaata gtcatcggag gtttatggtc gatggttcca tcttttttta gggttggttt
    44761 acgattgatt gattccaaaa atccttcgga gcgtagcttg gtcggtgtgg agttctctga
    44821 accagcaagt tctaggattc tgatttcctg tttctttgaa tttgtgaagt gattgctgac
    44881 aaataaaccc gcccgatttc cttctgcttt gaaactgggg ccaatgtggg tgacgaaaag
    44941 ctcgggatca ttcgtttgaa tatgtctgtc gacaagtatg acagggatcc ctgctcgctt
    45001 tgcttctttt aatacagagt cccacccgga ttcttgcaaa ggagtaaaaa tgatcatatc
    45061 cactttatag gcaatgaacg tccgtatatc ttggatttgc cgttcctgat tcatgtagcc
    45121 atttcggtag agaacttggt aatcttcttt ttcaagcgca gtgataattg attcagtatg
    45181 ctttttccgc cagctactct ccgttcctga ttgcgaaaaa ccaacgacta gtgggtcagg
    45241 tgcttccttt gtattaggtg tacaccccat catttggtaa gcgattacaa caagggctaa
    45301 aaaaaataaa acacgtttca ctttaaatca ctccatctgg atttgttagt actatcttat
    45361 cagataaaag ggaaaatcaa agtcaaaagg aatcaatcga aaaaaatcca agaaacttaa
    45421 aaaaatccaa gacaaaaaaa gtacacctaa aaaatttaaa gtaaatccca taaaaaaatc
    45481 aatgttaacg ctttctttat tagctatact cggtgtatca attgaaatgg gggataaaaa
    45541 atgaaaaaca aatttagaaa gattgttggg actatcgcta ttttgaccgc aagcattcta
    45601 ttaagtgcgt gtggcaattc aggatctgca gatgatagta cggggtatgt aggaatcgct
    45661 atgccgacca aatcagcaga aagatggatc gctgatggga acaacatggt ctcggaatta
    45721 gaaaaactgg gttataaaac agatcttcaa tatggagaag ataaagtaga aaatcaagta
    45781 gcacaaatag aaaatatgat tacaaaaggg gtagatacac ttgtgattgc ttctatcgat
    45841 ggttcggctt taactgatgt gttagctaaa gcaaaagaag cagatatcaa ggtgatcgcc
    45901 tatgatcgtt tactgatgaa ttcagaaaat gtcgattatt acgcgacttt tgataatttt
    45961 ggagtaggtg tatcgcaagc agcttatatt gaagagcact taggattgaa agaaggaaaa
    46021 ggaccattca cgattgaatt atttggtggc tcgcctgacg acaacaacgc actaatcaat
    46081 tacaacggag tgatgtctgt tttacaacca tatatggaca acggtcagtt ggtcgtgcca
    46141 tctggacaga cgagtttcag tcaaatcgct acgcttcgct gggatggttc tacggcgcaa
    46201 gcaaggatgg ataatctgtt aagcgcaaat tatactgacc aaacattgga tgctgttttg
    46261 tcgccatatg atccaataag tttaggaatc atttcgtcat taaaaggcgt ggggtatggg
    46321 agtgaaagta aacctttacc tgtgattact ggacaagatg cgacagttgc tggcgttaaa
    46381 tcgatcattg ccggggaaca aacacaaacg atctttaaag acacacgtat cttagcaaaa
    46441 aatacgattg aaatgatcaa agcaatcagt gatggagaag aggttccggt caatgatact
    46501 gaaacttatg ataatggggt gaaaactgtc cctacgtatt tagcaaatac agtatctgtc
    46561 gataaagata attatcaagc agagctgatc gacaccgatt attataaaga atccgatctg
    46621 aaaaattaag aggaaccaaa caaggaacta aagagatcta agtcagagag aggataagaa
    46681 ttatggcgga ttgtatttta aaaatggcag atatcaccaa aaaattttct ggaatccgag
    46741 cgttagattg cgtgaatctg atgattgaac gtggggaaat ccatgcattg tgcggagaaa
    46801 acggagcggg aaaatcaaca ttgatgaatg tcttgagcgg cttgtatcca tatggctcct
    46861 atgacgggga aatcttttat gatggaaagc tgtgtcaatt taaagatttg aaagatagtg
    46921 aagaaaaagg catcgtcatc attcatcaag aattagcact aagtccttat ctttcaataa
    46981 aagagaatat ttttctcgga aatgaacaag cagaaagagg cgtgattgat tgggaactga
    47041 cagaaaagaa aacatatgaa ctgctgaata aagtcggttt gtctatcgac ccgaatcttc
    47101 tagtatccca gattggcgta gggcaacagc aactagttga aatagctaaa gcattatcaa
    47161 aatccgtccg tctgttgatt ttggatgagc ctaccgctgc attgaatgaa gaagaaagcg
    47221 cgaatttgct gagattgatc cgagagttga aagagcaagg tgtaacctcc atcattattt
    47281 cacataagct gaatgaaatc gtggatatcg cagatcgaat caccatttta cgggatggac
    47341 agacgattga gacactagaa aatgaaatga tcagcgaaga gcatattatt cgcggaatgg
    47401 tgggcagaga tttagttgat cgttatcctg aaagaaaacc ggatattgga gaagtttatt
    47461 ttaaagtaga agactggacg gtctatcacc ctcttgatca cgagcgaatc ataaacgacc
    47521 acatcaactt gcatttgaaa aaaggagaga ttgtaggaat agctggactg atgggagcgg
    47581 gcagaactga attcgctatg agtctatttg gacattctta tggaagcaag atatccggac
    47641 gtatattaaa ggaaggggca gagatatcag ttaagaccgt tccttcagcc attgcaaacg
    47701 gactcgctta tgtctcggag gaccgaaaat ctttaggact gaatctgctg atggatattc
    47761 gggaaaacgt gacgctgagc agtttggata aaataagtca aaaaggagta ttagataaag
    47821 aaaaagaagt aactgaggca gaaaatttcc ggaaaaagat gcgtataaaa acaaactcca
    47881 tccatcaaat tgtcagtagt cttagtggtg ggaatcaaca aaaagtcgtt ttatccaagt
    47941 ggctgatgac acaacccgat attctttttt tggatgagcc aacccgtggg atagatgttg
    48001 gggcaaaata tgagatctac acgattatcg aagaaatggc agcaaatggc aaagctgtct
    48061 gtcttatctc ttctgaactt cctgaaatat tagggatgtg tgatcgaatc tatacgatga
    48121 acgaaggacg tattacagga gaagtctcgc gagaagatgc agatcaggaa gtcttgatga
    48181 aattaatgac gaaagaagag gtgggttaag ttggaacagg caaaaaatct tacggataaa
    48241 aaagagaaaa aactaaattt gaaaagtaga gcagctgatc tttttggtcg ctacagcatg
    48301 gtgatcattt tagcgggact acttattgcg tttcaattga tgacggatgg tattttctgg
    48361 cgtccattga atataactaa ccttgttctg caaaatagcc atatattagt actagctgca
    48421 gggatgttat tagttgtgct cttaggtcat gtggatttgt cggtagggtc agtgatggcg
    48481 tttgttggtg caattgcggg catgatgatg gtcaatcgcc aaatgaaccc gtggatgaca
    48541 gttatcgcat gtcttgcagt aggcgggctg atcggcgcat ggcaaggttt ttgggtagct
    48601 tatgcaggga taccggcgtt tatcgtgact ttagcaggat tgctgatgtt tcgtggactg
    48661 acacaagttg ttctaggagg ccaatctcta gcaccttttc cagctgtttt ccaaaaaatg
    48721 tctacgggtt atttaccaga cttaagcgaa ggaagcagcc ttcacttctt gacattgatt
    48781 ttaggaatga tcatcacgat cgtgttagtt gttggtcaat ggcgaacaag aaatcgtcgg
    48841 aaaaatcatt tatttgaagt ggaatctcca acagctttct tggtaaaggc ggtatttaca
    48901 gcagtcgttg tactaggaat aacttatatc tttgcctctt atcaagggta tccgattatt
    48961 ttgatcattc ttggtttgat cgttgcagca tatgggtttt tgacaaataa aacagtagca
    49021 ggtcgacaga tttatgcgac gggcggaaat cgaaaagcgg ctgaactatc agggatcaaa
    49081 acaaagcgaa tcacgttctg ggtattcgtc aacatgggag tcatggcagc tttagctgga
    49141 ttagttttag ctgctcgatt gaatgcggca acacctcaag caggtacatc gatggaactg
    49201 gatgcaatgg cggcagtata ttttggtggt gcttcgactt ccggcggcat tggaacaatc
    49261 atgggtgcga ttgtcggtgg cttggtcatg ggtgtattga acaatggcat gtcgatttta
    49321 ggcgtcgggg tagactggca gcaggcaatc aaaggattga tcttgctttt agccgttgtg
    49381 ctagacttgt ataataagaa aaaacgaaca acgtaggaga acgccggtta ttcagaaaaa
    49441 agactgtgac aagacatttg tcacagtctt tttttcgcta aaagcgaaca ttcattgttt
    49501 cgtttgtata gactaaaaat aatatatgtt tttttaccat tcgtataaat tctctttttg
    49561 ctcttgattt ttttgcttaa ttgagttaaa ttacataggg cgctaaaaaa agccttgatt
    49621 aaattaataa tgttcgtgtt ttgctggatg tgaacatcag gaggataatg taatgaaagt
    49681 atttgattac gaagatattc aattaattcc taataaatgt atcgtaaata gccgttctga
    49741 atgtgataca acggtcacat taggtaaaca tacattcaaa atgccagtag tgcctgccaa
    49801 catgcagacg attattgatg aaacaatcgc agaattctta gcggaaaatg gttatttcta
    49861 tatcatgcat cggtttgatg aagcagctcg aattccgttt atcaaaaaaa tgaaaaagcg
    49921 tggattgatt acctcgatca gtgttggcgt caagaaagag gaatattcct ttatagagaa
    49981 gttggcagaa gaatcgctaa atcctgatta tatcactatc gacatcgcgc atggacatgc
    50041 taactcagtt attgatatga ttcagcatat taaaaaatat ttgcctgaaa cttttgtgat
    50101 tgccggtaat gttggtacac cggaagccgt ccgtgaattg gaaaatgcgg gcgcagatgc
    50161 aacaaaagtc gggattggtc caggaaaagt atgtattaca aaaatcaaga caggctttgg
    50221 gactggaggc tggcaactgg cagctcttag atggtgtgcg aaagcagctc gcaagccgat
    50281 catcgctgac ggtgggatca gaacacatgg cgatattgca aaatctgtcc gttttggtgc
    50341 gacaatggtc atgattggtt cattgtttgc cggtcacgag gaatctcctg gcgaaacaaa
    50401 agtcgaaaat ggaatcgtgt ataaagaata ctttggttct gcttcagaat tccaaaaagg
    50461 cgaaaaacga aatgttgaag gaaagaaaat ctggatccaa cacaaaggat ctttgaaaga
    50521 tacactagtg gaaatgcaac aagaccttca atcatctatt tcttatgctg gaggaagaga
    50581 tctggaagcc attcgaaaag ttgactatgt catcgtgaaa aattcgattt ttaatggaga
    50641 cacaatctaa aaaataaata aaatattagg atgttgtgaa aaagttgtcc tgcattaagt
    50701 aataagaaca gccaaacaaa aatagttct
//
LOCUS       DAXLPY010000012        50327 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.012, whole genome shotgun sequence.
ACCESSION   DAXLPY010000012 DAXLPY010000000
VERSION     DAXLPY010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.012"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(87..266)
                     /gene="rpmF"
                     /locus_tag="ACF3UF_000801"
     CDS             complement(87..266)
                     /gene="rpmF"
                     /locus_tag="ACF3UF_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFD3670951.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(324..893)
                     /locus_tag="ACF3UF_000802"
     CDS             complement(324..893)
                     /locus_tag="ACF3UF_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFD3670952.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1079..1981
                     /locus_tag="ACF3UF_000803"
     CDS             1079..1981
                     /locus_tag="ACF3UF_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFD3670953.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2016..3800)
                     /gene="pyk"
                     /locus_tag="ACF3UF_000804"
     CDS             complement(2016..3800)
                     /gene="pyk"
                     /locus_tag="ACF3UF_000804"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFD3670954.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3874..4836)
                     /gene="pfkA"
                     /locus_tag="ACF3UF_000805"
     CDS             complement(3874..4836)
                     /gene="pfkA"
                     /locus_tag="ACF3UF_000805"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFD3670955.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5004..8318)
                     /gene="dnaE"
                     /locus_tag="ACF3UF_000806"
     CDS             complement(5004..8318)
                     /gene="dnaE"
                     /locus_tag="ACF3UF_000806"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFD3670956.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8549..8734
                     /locus_tag="ACF3UF_000807"
     CDS             8549..8734
                     /locus_tag="ACF3UF_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFD3670957.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8796..9992)
                     /locus_tag="ACF3UF_000808"
     CDS             complement(8796..9992)
                     /locus_tag="ACF3UF_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFD3670958.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10127..11587)
                     /locus_tag="ACF3UF_000809"
     CDS             complement(10127..11587)
                     /locus_tag="ACF3UF_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFD3670959.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILTKEKGLEQYLF"
     gene            11880..12689
                     /locus_tag="ACF3UF_000810"
     CDS             11880..12689
                     /locus_tag="ACF3UF_000810"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3670960.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12875..15028)
                     /locus_tag="ACF3UF_000811"
     CDS             complement(12875..15028)
                     /locus_tag="ACF3UF_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFD3670961.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(15322..16170)
                     /locus_tag="ACF3UF_000812"
     CDS             complement(15322..16170)
                     /locus_tag="ACF3UF_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3670962.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(16394..18334)
                     /gene="thrS"
                     /locus_tag="ACF3UF_000813"
     CDS             complement(16394..18334)
                     /gene="thrS"
                     /locus_tag="ACF3UF_000813"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFD3670963.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(18671..18850)
                     /locus_tag="ACF3UF_000814"
     CDS             complement(18671..18850)
                     /locus_tag="ACF3UF_000814"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFD3670964.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(18897..20720)
                     /locus_tag="ACF3UF_000815"
     CDS             complement(18897..20720)
                     /locus_tag="ACF3UF_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3670965.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            20998..23277
                     /gene="helD"
                     /locus_tag="ACF3UF_000816"
     CDS             20998..23277
                     /gene="helD"
                     /locus_tag="ACF3UF_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFD3670966.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(23370..24017)
                     /locus_tag="ACF3UF_000817"
     CDS             complement(23370..24017)
                     /locus_tag="ACF3UF_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3670967.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(24196..24915)
                     /locus_tag="ACF3UF_000818"
     CDS             complement(24196..24915)
                     /locus_tag="ACF3UF_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3670968.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(25046..26197)
                     /locus_tag="ACF3UF_000819"
     CDS             complement(25046..26197)
                     /locus_tag="ACF3UF_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFD3670969.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(26414..27154)
                     /locus_tag="ACF3UF_000820"
     CDS             complement(26414..27154)
                     /locus_tag="ACF3UF_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3670970.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(27158..27481)
                     /gene="rsfS"
                     /locus_tag="ACF3UF_000821"
     CDS             complement(27158..27481)
                     /gene="rsfS"
                     /locus_tag="ACF3UF_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFD3670971.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(27538..28131)
                     /gene="yqeK"
                     /locus_tag="ACF3UF_000822"
     CDS             complement(27538..28131)
                     /gene="yqeK"
                     /locus_tag="ACF3UF_000822"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFD3670972.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(28115..28765)
                     /locus_tag="ACF3UF_000823"
     CDS             complement(28115..28765)
                     /locus_tag="ACF3UF_000823"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFD3670973.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(28775..29086)
                     /gene="yhbY"
                     /locus_tag="ACF3UF_000824"
     CDS             complement(28775..29086)
                     /gene="yhbY"
                     /locus_tag="ACF3UF_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFD3670974.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(29102..30211)
                     /gene="yqeH"
                     /locus_tag="ACF3UF_000825"
     CDS             complement(29102..30211)
                     /gene="yqeH"
                     /locus_tag="ACF3UF_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFD3670975.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(30208..30735)
                     /locus_tag="ACF3UF_000826"
     CDS             complement(30208..30735)
                     /locus_tag="ACF3UF_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFD3670976.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(30915..31700)
                     /locus_tag="ACF3UF_000827"
     CDS             complement(30915..31700)
                     /locus_tag="ACF3UF_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFD3670977.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(31693..32562)
                     /gene="accD"
                     /locus_tag="ACF3UF_000828"
     CDS             complement(31693..32562)
                     /gene="accD"
                     /locus_tag="ACF3UF_000828"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFD3670978.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(32563..33942)
                     /locus_tag="ACF3UF_000829"
     CDS             complement(32563..33942)
                     /locus_tag="ACF3UF_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFD3670979.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(33950..34369)
                     /gene="fabZ"
                     /locus_tag="ACF3UF_000830"
     CDS             complement(33950..34369)
                     /gene="fabZ"
                     /locus_tag="ACF3UF_000830"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFD3670980.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(34394..34870)
                     /gene="accB"
                     /locus_tag="ACF3UF_000831"
     CDS             complement(34394..34870)
                     /gene="accB"
                     /locus_tag="ACF3UF_000831"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFD3670981.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(34873..36108)
                     /gene="fabF"
                     /locus_tag="ACF3UF_000832"
     CDS             complement(34873..36108)
                     /gene="fabF"
                     /locus_tag="ACF3UF_000832"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFD3670982.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(36127..36864)
                     /gene="fabG"
                     /locus_tag="ACF3UF_000833"
     CDS             complement(36127..36864)
                     /gene="fabG"
                     /locus_tag="ACF3UF_000833"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFD3670983.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(36876..37793)
                     /gene="fabD"
                     /locus_tag="ACF3UF_000834"
     CDS             complement(36876..37793)
                     /gene="fabD"
                     /locus_tag="ACF3UF_000834"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFD3670984.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(37900..38124)
                     /locus_tag="ACF3UF_000835"
     CDS             complement(37900..38124)
                     /locus_tag="ACF3UF_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFD3670985.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(38177..39139)
                     /locus_tag="ACF3UF_000836"
     CDS             complement(38177..39139)
                     /locus_tag="ACF3UF_000836"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFD3670986.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(39149..39589)
                     /locus_tag="ACF3UF_000837"
     CDS             complement(39149..39589)
                     /locus_tag="ACF3UF_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3670987.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            39895..40860
                     /locus_tag="ACF3UF_000838"
     CDS             39895..40860
                     /locus_tag="ACF3UF_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFD3670988.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(40917..41147)
                     /locus_tag="ACF3UF_000839"
     CDS             complement(40917..41147)
                     /locus_tag="ACF3UF_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFD3670989.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(41233..42120)
                     /locus_tag="ACF3UF_000840"
     CDS             complement(41233..42120)
                     /locus_tag="ACF3UF_000840"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3670990.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(42209..43432)
                     /locus_tag="ACF3UF_000841"
     CDS             complement(42209..43432)
                     /locus_tag="ACF3UF_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD3670991.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(43449..44495)
                     /locus_tag="ACF3UF_000842"
     CDS             complement(43449..44495)
                     /locus_tag="ACF3UF_000842"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD3670992.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(44659..46386)
                     /gene="ptsP"
                     /locus_tag="ACF3UF_000843"
     CDS             complement(44659..46386)
                     /gene="ptsP"
                     /locus_tag="ACF3UF_000843"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFD3670993.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(46386..46652)
                     /locus_tag="ACF3UF_000844"
     CDS             complement(46386..46652)
                     /locus_tag="ACF3UF_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFD3670994.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            47131..49365
                     /locus_tag="ACF3UF_000845"
     CDS             47131..49365
                     /locus_tag="ACF3UF_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3670995.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            49513..49833
                     /locus_tag="ACF3UF_000846"
     CDS             49513..49833
                     /locus_tag="ACF3UF_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFD3670996.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(50038..50262)
                     /locus_tag="ACF3UF_000847"
     CDS             complement(50038..50262)
                     /locus_tag="ACF3UF_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFD3670997.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
BASE COUNT        14350 a        10801 c         8779 g        16397 t
ORIGIN      
        1 atatttttta tttaccgact acaaaaaaat aaacctcaag gctccatggt tagccttgag
       61 gttttacatt ttctaattaa aatgtattaa gcttcttttg acattacgtc cttaccatca
      121 tagtaaccac aatttgcaca tacgtgatgg ctttttttca tttcaccaca gtttggacat
      181 tcgtttaacc ctttgattgt caatttgtag tgtgtacgac gttttgcttt tttagctttt
      241 gatgttcttc tagctggtac tgccattttg ctacacctcc ttgtaaagtc ttgtatctaa
      301 attagacaca atatattcca atcttacttg ttatcgtcgt cttttgattt agaatcaaaa
      361 agttcagata gttttgcaag acgaggatca attttattct cggcttcttc catttttctg
      421 cgctggtatt cttcttcgga aacaacttcc caatcattgc cttttggaag ttctgttgct
      481 gcttcctctt cttttgtcaa tacccgcatt ggaatcgcca ataagatgtt gtcttcaatc
      541 gactctgcta aattcaataa tggaccttca attagcaaaa tctcatctgc agacatttgt
      601 tcatctctac tttggaattg ttcttctgtc atgaatactt cgtctacaga aaaatccatg
      661 ggcagttcaa caggttctag tgaacgtgtt gaaggaactg tcaaagtcgt ctgcacagtg
      721 taatgaacga tatagccttt cttatcaact gagaccaaac cttcgacttc cactggcgca
      781 acatcaagta ttaaattgtc tcgcttcatg agagcggctt tcaagtcgag cgtctcatga
      841 aaagttaacg gtgtctcctg gtattttctc aattccaata aagaccattt catttttcat
      901 cactcctaag caacaaaagc aattatacag ggcaaaaagc atgttgtcaa tgaaattttc
      961 ttgacacctt gcagttcata aaaaaacaga aaaatcttta ttagaaagcc tctgtttgct
     1021 atcatcctca gaatcattta caataatcat tattccatta aaggagcgga tgatcttcat
     1081 gaacacgaaa gatatcgaat actatgtcca aatcgtcaaa caaaaaaatt ttacgaaagt
     1141 ggctaattat ttccgtgtga gccaacctac tattacatat gcattacaac gtcttgaaaa
     1201 agagtttgac accgtactta ttacaagaga tcgatcgcat cacgaattaa tcgtcacgcc
     1261 ttctggaaag cagctgtttc tccatgcaca aaccattctc caagagattt ctactgcaag
     1321 agctgaaatc actcagttgc aaaagaaaaa gcttcgtttt ggcatgcctc ctattatcgg
     1381 caatgaatac tttcctaaac tgtcaagtta ctttatcaag catgaattga tgaatcaaat
     1441 tgagattacc gatggaggct ctcgggactt atacgggatg atccgacaag ggaggatcga
     1501 tttagctgta ttaggctcaa cacagccaat cgtggatcaa tatttagaaa cagagttact
     1561 tttggacaaa cgtttcatga tcgtcgtgcc acctacacat cctctttcca agcaggatac
     1621 tgtctctttc aaagatatag cagatgaaca gtttgtacta ttgaacgaac attatgtcca
     1681 ccccgcagca ttcactaagc tttctaaaca aacacatact catccaaaag ttgtttatca
     1741 aagcaatgac ttgacgattt taaagagtat ggtccgagaa aatgtgggta tcggtttttt
     1801 ggcagagatt gctgtccatc ctgaagatca tttagtttgc ctccctcttt cagatgaagt
     1861 tcagcctcgc ttcttgattt cattggcaaa acgaacacag cagatcgtca cgcctcttca
     1921 agaacaagta gtccaagtta tccatgaatt cgttacagca caaaaaaaca gctcttcgta
     1981 aaagaagagc tgtttttatt ttttattaag ctaaattaga tagctgttgt ttcgccacgg
     2041 taaacgatgc cgcgacgtga atcaacggta atcaattcac cttctgtaat tgttgttgtt
     2101 gcgcctttag caccaacgat tacaggaata tcttgtgcaa ttcctacaac tgcagcgtga
     2161 gaagtcaatc cgccttcttc aacgataaca gcagctgctt tttcgattgc aggcatatat
     2221 tctttgtcag ttgatggtac aactagaacc attccgtctt ttgctttttt tacagcttct
     2281 tcagcagatg aagcaataac tgcatttgca acgacagatt tttgtccaac gccttgagct
     2341 tctaataatt tagaaccaat catttgaatt ttcatcacgt tagttgttcc gcgttcacca
     2401 actggtacac cagcagtgat caagattaaa tcgccttctg atgcgaaacc taattcaaca
     2461 gcttttttag ctgctagttc aaacatttca tcagttgttg atggtttttc agcaactgtt
     2521 gggtaaacgc cccagtttaa catcaaacca cgttttgtgc gttcgtcaaa agtaacagcc
     2581 aagatatctg catctggacg atattttgaa atcatttttg cagtgtatcc tgattcagtt
     2641 gcagcaacga ttgttttcac gcctagattt tttgcagcac gagctacaga taaaccgatt
     2701 gtttcagtta catctgtttt atcgaattcg ttcaattgga atgtacctaa ttctgataat
     2761 gcattttcag cttcttggtc gatacgtgcc attgttgaaa cagcttcaac tgggtagtcc
     2821 ccgtttgcag attcaccaga tagcattgtt gcatctgtgc catcaaatac agcgttagca
     2881 acgtcagaag cttccgcacg tgttggacgt gggttttctt gcattgattc taacatttgt
     2941 gtagcagtga taactgggat accagcagca ttacattttt tgataatgcg tttttgaacc
     3001 attggtacta gttcagctgg gatttcaaca cccatatctc cgcgggcaat cataacaccg
     3061 tcagaaactt tgatgatttc gtcaatgttg tcgatacctt cttgagattc gattttaggg
     3121 aagatttgaa catgagtcat gtctttttct tctaagattt cgcggatatc tagaacgtct
     3181 tgtgctttac gtacaaaact tgcagcgata aagtcgatat cgttgtctaa accaaaacga
     3241 atatcgtcag catcttttgg agtaatacct ggcaaactaa tagaaacgcc tggtgcattt
     3301 acccctttac gtgatcctag catacctgca tttttaactt ctacgactaa ttcacggttt
     3361 gcttcgtctt tttcaatgat ttgcatatcg atcaaaccat catcaaataa aatgtgtccg
     3421 ccaacgtgaa catcgtcaaa taatcctggg taagtaaccg cgattttttc ttttgaacct
     3481 acatgttcag gatccataga gatgcgtgtt tgatctccta cttcaaattt gatgtatcct
     3541 gcacgaccaa aatcagcttc tgttgtgcct tgaacagttg tacggatttc agctcctttt
     3601 gtatctaaaa gaataccgac atcttttcct gtctttttaa ctgcttcacg gaccatagtc
     3661 atacgtgata attgttcttc atggtcacca tgagaaaaat taaagcggaa gacatttgcc
     3721 ccagattcaa tcaattgaga aataatttct actgagttac ttgctggtcc taatgtacta
     3781 acgattttgg tttttttcat ttaaaaaact ctcccattca attttgttta tttaaagctg
     3841 tacacagctt aaatagcttg gtttctttca ctcttaaaat gaaagtgaat tatttagatc
     3901 atatagtgat aagtctggtt tatgtttgtt gttttcaagt gtatcaatga tgtcagacgc
     3961 aacgatttcg ttgtcatgga taccgacaca taatccacct tttccttctt gaagcaattc
     4021 gacagcgtaa gcaccgaatt tacttgccaa cacgcggtcg cgtgcgcttg gtgctccacc
     4081 acggacaacg tgtcccaaga tagatacacg tgtatgatag tcaccaaatt ctgaaagttt
     4141 ctcagcgaat tcatttccgc ccattacacc ttcagccaag atgatcaagc aatgtttctt
     4201 cccgcgatcg cggccttctt ggattttttt agcaactgaa gccatatcaa aatcatgttc
     4261 tgggatgatg atttcatccg ctccgccagc cacacctgac cataaagcga tgtctcctgc
     4321 attgcgtccc attacttcga taacgaatgt acgaacatga gaagtcgctg tgtcacgaat
     4381 acggtcaatt gattctagta ctgtattgat tgctgtatca aaaccgattg tgaaatcagt
     4441 cccaggaata tcattatcga ttgttccagg aatacctact gctgggaaac cgcgttttgt
     4501 caaagccatt gcgccatgat aagagccgtc tcctccgata accactagac cttcgattcc
     4561 gaattttttc aattgttcga ttccttttaa ttgaccttct tcagttgcaa attctggata
     4621 acgtgcagaa tacaagaatg taccaccacg ttggatcttg tcacctacat ctgccacatc
     4681 aagacgacga atatctccag caactaaacc ggcaaaacca taattgatcc cgtatacttc
     4741 cagtccttcg taaatacctt tacgaacaac ggcacgaaca gctgcattca ttccaggtgc
     4801 gtctccgcca ctggtcaaaa ttccgatgcg tttcataata aacattcacc tcattaaaat
     4861 actttatcct aagtatgact taggtttaca accatttttg cgttaaccac gactaacatt
     4921 ctaacattat ttttctcact tgtcttgatt tacggataaa aaaatgaaaa aaaatgaaag
     4981 caagtagtat tttttaccgt aagttatttg aaaaccacat tatcttcgcc aagcagataa
     5041 ataagttgcc cctttatact cttgctgtca tccacccaat aagcatctga cagaactact
     5101 tttcgttgcg ttttttcgtg atacataact actggtatat atcctgggtg tttctgaaaa
     5161 atcacttgta attgtttcat tatctcggga tcttcccgtt cttctgtaat acgcaaatag
     5221 caagtttgtg aaggatactg ggcttctaac tggttaggat cagcaaagct ttctccaatt
     5281 agttgcagtt cctgattata tttgctgatt tcgctccgcc cttgaacaaa gatcactcga
     5341 tcaacggcaa acaaattacg atatttacga taaagagttg gaaaaactgt gacagaaatt
     5401 tctccactac tgtcggttcc ttcaacaaag gccatcagtt ctcctttttt tgtccgaatt
     5461 tctctaactt ccttgatcat cactaataaa ttgactggtt gattagggac gatatctgta
     5521 atcagctgaa cttgtttagc taaacgaaga cgatcaaacc cttctgcagg atgacctgac
     5581 aaataaatac ctaagtactc ctcttccagc ttcaagcgtt cttctagtgt atagtcagcg
     5641 acttcttctt cttttaatgc catgattccc agcaagtcaa gacttccacc actgtaaacg
     5701 atattttgga tttttccttc gagatcaagc atcaattgtt tcctgttagg agataattca
     5761 tcaaaaactc ctactgctgt cagtgattgc agtaactcta atttcagcca acgcttatcg
     5821 atccgtatga ggaattgatc cactgactgg aacgggccat tttgttttct ttcgtttaat
     5881 atatcttcta caaaatcacg ccgaatacct tttatcgctg tcagtccgaa tctgatttct
     5941 tccttattga ccaactcaaa actggaatta ctttgattaa tggacggcga ggaaagtttg
     6001 agtttatttt tacgtgcttc tgcaatatat tctttcaatt ttgatgtgtt atgccgaaca
     6061 gaattcatca ggctggtaaa gaaagcacct ggatgatggg cttttagata cgccatttgg
     6121 aatcccacga atgaataagc aaatgcatgt gaccgattga atccatagtt tgcaaatttt
     6181 tcgatatatt catatacggt cgctgctgtt ttttccgaat atccctgttg taatgctcct
     6241 gatacaaaat gcgacttttc ttcatctaat acgtcttttt tctttttact cactgcccgt
     6301 cgcagaatat ctgactgccc taatgtaaat ccagccatag tcgaggcgat ctgcatgatt
     6361 tgttcctgat agacgatcac tccatatgtg tttttcaaaa tcgggatcag tgaatcatct
     6421 gggtagcgaa tggcttcttt tcctttcttc ctggcaatga aggtatctat attttgcata
     6481 gggcctggtc gatacaatgc attgactgcg gcaatatctt cgatgttttc tggatctaat
     6541 cttcgtaaaa cgttccggat accagcagat tcaaattgaa atactcctga ggtttcgcct
     6601 cgttgaaaca agagcagcgt ttttgcatca tttagcggga tctcttttaa tcggatctca
     6661 tacccttcta ctcgcttaac agctttcaaa gtaaaatcaa taatcgataa gttgcgtagt
     6721 cctaaaaagt ccattttcaa aagaccgatt gcttctacct cattcatcgt atactgggtc
     6781 agaaaagctt catcagaacc gcgttggagc ggaactagtt caagtagatt cttatcgctg
     6841 ataactacac ctgctgcgtg agtcgaaaca tgtcttggca atccttctaa aatcactgca
     6901 gttttgaata aaagttggtt tttttcgctt gcctgaacta attctactaa ttgatgcgaa
     6961 gttttataag cttgggtcaa tgtgattttc aattgattgg gtattgcttt tgaccagcgg
     7021 tttgcttcac tttgcgataa accaaacact ctagctgcat ctctaagaac catttttgct
     7081 gccattgtgc caaatgttgc gatttgtgcc atatgatatt gtccatactt ttctcgaaca
     7141 taattcaata cttcttcacg tcgattgtca ggaatatcca aatcgatatc tggcatcgta
     7201 aagcgttcgg ggtttaaaaa gcgttcgaac agcaaatcat attctaatgg atccacatct
     7261 gtgatttcta acacataggc tactaatgaa cccgcagcag aaccacgacc tgcaccggta
     7321 acgattttgt ttctatgagc aaaagccatt acatcccata cgatcaagaa ataatcatcg
     7381 aatcccattt gatggatgac agataactcg tagtccaaac gttcttggta ttcctttgta
     7441 tagtcagtga ttcggcgttc cacttgcgaa tagcataact ctcttaaata ttctccagct
     7501 tgttttccat taggaactgg ataatgcgga agtaatttct gatggaactg gaattcaaat
     7561 gaaatcgatt cagctaaacg ctgggcgcct attacagctt gggaaagacc cgctttttcg
     7621 aatcgtttga tcatttcttg ttctgaaaga agatagacat ttgctgttag tggtaaagat
     7681 gcagataaat tttctaaagg tatttggctt ccctctttga tatgtttcat cacttcaagt
     7741 gcaaaaagtt cttcttgttg taaactagcg atgggatgta atgcacaaag cgaataattt
     7801 tcttttatca catactgata ccattcaggc aattgatcag gcgtgttttc tgtcaagccg
     7861 atataaaaat ttctagtaaa aacattttca agtaaaaact gccaatgacc gaaaaagtta
     7921 tcctctttat tgaaagcctc agaaacagaa tgatttgccg gaacaacaaa cgctagatgg
     7981 tcggtttctg tcatttctgc aagttccaat ttttcttgga tcatttttcg gctggaaagt
     8041 ttcatcagct gctgataacc tatttcatct tttgcgtacg caagcaagcc ataatttttt
     8101 tcttcataag tataactaag atgtaatcca atgattggct gtactccttc ttctacacaa
     8161 atacgataga attcaggtgc accgtataag acatctttat ccgttatggc taatgaagtg
     8221 tagccttgtt tttttgcttc ttgtacatat tctcgaatac gtatcgtact ttgtaaaaga
     8281 gaataagaag taattgtata aagttgtggg aaaaacatct tgcattccgc cttttttttc
     8341 gttaaaattc actagcgtta aaaggtttga tccttttact ttcattaaga tagcaggcgc
     8401 tgaagttgat tattccactt catttgcttg cttgtaatct gtaggaatga gttctttcgc
     8461 aagaactcaa attttattga gatttggtct cgtttcttta cattcaaaga aaatctggta
     8521 aaattaagat agaaaagagg tgttctttat gcgatatatc gttacattat tctgggctgt
     8581 cgttctaggt caagtagtcg gttatattgg tgctgcatta acaagcggaa catatgattt
     8641 tactttgaca acaatcattt cattcattgc gggtgtcatt atccttttga ttggtgcagt
     8701 tgcgccaaga aaagaaacct ctgcccattc gtaaaaaaac agccaagagc ttgagatttc
     8761 tcaagctctt ttttattttc tactcctcac caccattata atctgctgcg aagaacttta
     8821 cgaaagttga ataaagaaag aagaatattt gacagaacaa acaaacttgt cacaataaaa
     8881 acagcactgt aattataagc atgcgcgact gtcgatccta gcatgggacc taaaacttgt
     8941 ccaaagttgc taaacatctg attgtagcta tagattcggc tgactccttc ttgaggcgta
     9001 atcttactga tcagtgtatt gacagaaggc atcaaagcgc cagttgaaaa gcctaaaata
     9061 aagcgaagta tacctaattg gagcggtgta gtgacgaatg ccataggtaa ataacagcaa
     9121 aatgataaaa tgagtcctcc aattagaact ttttgattcc caatcttatc ccctagtttt
     9181 cctagtttcg gtgaagaaaa gacagcggaa acaccagcta tcgaaacaat caagccgctg
     9241 acaaaaagga tattttctgt acttccgctc aattcacgaa tatataaggt caaaataggg
     9301 ctgatcgtag tgattcctat ctgtaaaatc aaggtcgtaa tgaagagacc gatcaaaata
     9361 gagagatgat ccatttttga aaaaatttct ttggtgctta tcagatcttt tttctcgatt
     9421 ggatggaaat cttctttgac taagaaaatg gtcaataccg ttgtgatcat caacaaagcc
     9481 cctgtgatca agaatacatt ttccatacca aaccactgag ccagtgcacc gcccattgaa
     9541 ggtccgatca gatttccagc aatcgctccg gtagacaatg ttcctaacgc ccatccgctc
     9601 ttttctctag gtgcctgtga agcaatcatc gctgtggcat ttggaatata tccagacaaa
     9661 atcccattcc aaaaccgcat gatcaaaagc caatacgcgt ttggtacaaa agccaaagat
     9721 cccattgtta atgtcatccc tgctgctgca cggatcatca tgagttttcg gccttttcga
     9781 tcagctagat ttccccagat tggtgcaacc acggcagatg caaaagcagt cacagagatt
     9841 gctagtcccg aaaacaattc gatttgatct tttggtgttc ctagttgctc aacataaact
     9901 ggtatgaatg gcataactaa actaatactt gcaccagtga aaaaacagcc aatccacgca
     9961 atcactaaat tttttctcca attaatctcc atctatcatc cctctttcgt ctcttttatc
    10021 atacctattt tcgaataaac aagcaacgat ctcgccagta aaaagagaaa aatcccgcaa
    10081 aggtcatttt atatgtaacg ttctttttat gtaaaacaaa aagagatcag aacaaatact
    10141 gttccaatcc cttctcttta gttaaaatga tgaagttgat aatgaataaa atatcaacga
    10201 tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca attgtataga
    10261 aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata aagatcgatg
    10321 caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca aaagaagcca
    10381 tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt acaatggcga
    10441 tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact gaagtcaaac
    10501 cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt gtattcgatg
    10561 taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct ttatccattt
    10621 ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag aaaatacctg
    10681 tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat aaactgaatg
    10741 cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa gattgcatgc
    10801 cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa ttacctaacg
    10861 aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata ccaaggactg
    10921 tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact aaaatggctg
    10981 tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg gctaacgcag
    11041 ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg acagagctcg
    11101 aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt ccgacatacg
    11161 caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga atcgcccgaa
    11221 taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg caaataaaca
    11281 ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta aaagtgaaaa
    11341 atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac aatcccatta
    11401 ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg aagggcatac
    11461 ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca aagaatgtcg
    11521 ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa ccgaaaaact
    11581 tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata ataataaaaa
    11641 ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt ttcattcgct
    11701 tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg tttagcttat
    11761 gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga ttgctcttgt
    11821 taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa ggacccttat
    11881 tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa gattcgatga
    11941 ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat catgtcagta
    12001 ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta gaattaacaa
    12061 caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac tgggatggtg
    12121 aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa aaaaagcagc
    12181 taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac agttttgatt
    12241 tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg ctttctccta
    12301 aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt tttgcaggag
    12361 ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg acatggggtg
    12421 gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa ggcgtgcaag
    12481 agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt gacgagcata
    12541 atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac ggtactgacc
    12601 aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac ggtttagctg
    12661 tttatctgga aaaactactt aaactataat agagaattag attccacaaa aaagaggttg
    12721 tgacaatttt tgtcacaacc ttttttgccg agtaaacggt gttcaaaagc cagtttctcg
    12781 gtatgaagtc aaatttaagc aaaaatgtga gaagctattt tcacaaaatt tttcttcata
    12841 ctcgaaacta agcggctttt tcacgacctc ttttttattt tgccatgaac atatcataat
    12901 acgcgtccat tatttcttta gcaatcgtca agtttatgtg gtcttgttcg tctaataagt
    12961 tcggcaagac aacactgatg gcaatttccg gattgtctgt tggtccgtat gccacgatat
    13021 tactattgac tgtcgcaata tctggatgac cttccgcaac cgtttctgca gtccctgttt
    13081 ttgcggaaag gtccattttc gcactggcta atggtttggc tgttgtgtaa ggatcggtac
    13141 catggacaac ttggtggaat ccttcacgga ggatcgccat attttctgca gaaatattga
    13201 ccgtattttc tactgttgtg ccaatttctt tcttcacttc acccaagttt ccattttcgt
    13261 cattgccata gatcgctttg actaggtgcg gctgtactcg tttcccgcca ttagcgactg
    13321 ttgaagcata ttgagctaat tggattggtg tatatgtgtc aaactgtcca aatgccaaat
    13381 cggtaaagtt acctggagca taccattctt tgccattatc cgcattgaac ttcttcatat
    13441 aatcaacaga acgtgagatc ccaggagatt cattcggcaa atcgatccca gtcgttgtac
    13501 caagaccaaa ctctttgaaa gagtctctca attgctgata agctttagct tcttcatcta
    13561 aactaggtag tcccattcca ggtgtatagt ctagtcctaa catctttaac gccactttga
    13621 tcatatacgt attagaagac aattccgatg ctttgactgc atcaagagca acttgtccgc
    13681 ttcgattaaa gacagagctt ttttctgaag caccttgcag acgaatcggc tcatcaatca
    13741 aaacttgatt tccgctgatc gcgttacttg cccagcctgc tgtcaaagta ccagccttga
    13801 ctacagaccc tggatcaaag gcgctagtaa tcgtgcctaa agcattctcg gtgatttctt
    13861 tggaaccttg ttcatgactg aaaccagtca ttgctagcac ttctcctgtc tgaggattca
    13921 tagccactgc ataagcacca ggcgaatact gtgctttgcc gttgttgatc aatgtttgat
    13981 aattcctttt caaaatttct tctacttttg attggaattc tgcattcata gataacatta
    14041 aattagaacc tttttcccca gagaagattt ctttttgatt cgaaacattt ccttcattat
    14101 caagggaaac ttcatattgg gttttggttc cttgcaggac atcttcatat tgtttttcca
    14161 aataactttg tcctacacgg tcattccgag aataaccttt tgctaggtat ttctctgctt
    14221 catctgctgg aagtccttgc ttttcagtcg tcacactgcc aagaatactt ttcagtgaac
    14281 ttgctgcatt atattctcgt gtccagtctg tgccagtcga aactcctgga agttcagaag
    14341 cgcgttctgc cacaacagct aactcttgat cagtaacacc agagtttttg atatagacag
    14401 tgtttaattc atatgcacta ttcatccgtt taaagatggt agcaattttt aattgctcct
    14461 cgtttaaatt aatctcatca gctgtgactt tattgaccat cgcactatat tgttcgctgt
    14521 tccctaattg cttttctttt gccgaaagtc tttttgtggc ttctttcaaa tgtttgggat
    14581 cagccagcca aaaatctttt ttatctctat ctgtcagatt ttcatctacc ggaacatcga
    14641 tcagcgagtt cagcttcgtt gcgatttcaa gcaaatcttt agccgtaact tgtgttcctc
    14701 tcgtatatgt gatggcctga ttcgctttat tcgtaactaa agcttttcct gtggagtcgt
    14761 agatcattcc gcgaggagta ctttcttgga ccgtaatcgt agaagtagac ttcactcgcg
    14821 cctccatctc ttcgccgttc acgatctgca aataacccaa tctagcaatc aacgcaacaa
    14881 ataacgtaaa tataatgaaa aaaagaaaat ttaagcgaaa aggaacatgg gaccggcgaa
    14941 acgttttgtt cttaggttct tgtgcacctt ttcttatttt ttctaaccaa gaagtattta
    15001 atattttttt cataaaatct ttcatcattt cctatccttc cgcctattta cattcatgct
    15061 tcattgtacc caaaaacttc ttaataaaaa agaaaaaatg ggcggagcaa gaaattcttt
    15121 acctaatttc aagataaaat caactttttg tttcacagca atcacttaaa gttacatatc
    15181 caactatttt tttcattaaa aaataaactt atttttgaaa attatgtttt cttaagtcgt
    15241 gaaacacttt gatggatcat ttatttgtgg aaaactacgt tttgttattc taaaaaactt
    15301 atataaaaaa tagtaaggtt tttatttcga atccataaaa tattcttgga ttgcttctcg
    15361 tgtttttttc actttttcgc taagcttttc gtttttagcc atatagaaat aaaaaatgat
    15421 atcgatcgta gcaaattggg ccaaaagtga attagttgcc gcacttcgat tcgtgatttc
    15481 ttttggtcta gatgtttgta cgagtacatc ggctatcttg ctaagcgggt tatttccaaa
    15541 ttgcgtcaac gcaatgattt cgatattcat gcttttcgcc agctcggcta atgcgactac
    15601 atctgcactt ctacctgagt ttgaaacaag ccaaagcact ttctttttct cattgctgac
    15661 aagttgcggg agcaagacgt ggatatcttt ttcaaaaatg attggcttac cgacacgaga
    15721 ccatttttgc agaatatctt ctactactaa agaagaggcg ccaaccccat ataaaaaaac
    15781 agtctctgcc gattccaaac actctacgac tttttggatc gtttcttctt ctagaatatc
    15841 tactgtttct tttatcgcta cttgtgcatt gttaccaagt ttgtttttga tagagtaaaa
    15901 ggactcattt gcttctatat cactaaaacc ttcatcgatt ccagtctgta gttctgttga
    15961 aatcgtgatt ttgaagtccg tcagactttg aaaaccgatt tttttggaaa aacgtacaac
    16021 tgtcggcgca ctcaacccgg aagcttctgc taattcatta gctgtcattg tagggacctt
    16081 ctcaatatta ccgataatgt agttggccaa ctttttttct gctgaagaat aatcttccat
    16141 catactttca atacgactaa ttacgctcat aagttcctcc acccttttaa tgatagtcta
    16201 tgtaagtata ccatatcaga cccttattca cggtcgtata ctggataaaa aacaaaaaaa
    16261 caatccgccc aacagaatat cttatcccat caatcccaca gattctattg agcatctgtg
    16321 tctttgagga atacctgtta tctattgttc ggattgcttt ctatctacta cttttttaca
    16381 ggaaatttac ctattagttt tctctgctgt aatttttgac ttctgcttcc atagcatcaa
    16441 taaagatatt caaatcttct acagctgttt ctttacttcc ataacgacgt acgttcactg
    16501 ttgcatcttc caattccttg tctccaacaa ctaattggta agggatcttt tgtgtttgag
    16561 aggcacgtat cttatagccc attttttcat tacgatcatc aacttctaca cgcaacccct
    16621 tcatttgcaa acgttctttg atttcataag cataatcgcc atgtgcatca acagaaacag
    16681 ggatgattgt tgcttgtata ggtgccaacc atgttggaaa agcgcctttg tatacttctg
    16741 ttaaataagc gacaaaacgt tccattgtag aaacaattcc gcggtggata actactggac
    16801 gatgcgtatt ttccccgtct tctccaacat atgtcaaatc aaagcgctct ggcaataaga
    16861 agtctaattg tatagttgat aatgtttctt ctgtaccaag agctgttttg acttgaacat
    16921 ctagttttgg tccgtaaaag gctgcctcgc cttctgcttc aaagtaatct agttctaatt
    16981 catccatagc ggctttcagc attgcttggg ctttttccca cattgcgtca tcatcaaaat
    17041 atttatctgt attgtttgga tcgcgatagc tcaagcggaa acgataatct gtaatattga
    17101 agtcagcata tactgccacc atcaattcaa gcgtacgttt aaattcatct ttgatttgat
    17161 caggacgaac aaatgtatga ccatcattca acgtcatttc tcgtacacgt tgtaaacctg
    17221 acaaagcacc tgatttttca tagcgatgca tcattcctaa ttcagcgata cgaattggta
    17281 attcacgata agaatggatc gtgtttttgt agaccatcat gtgatgaggg cagttcattg
    17341 ggcgaagaac aagcatttcg ccatctccca tatccattgg cgggaacatg tcttcttgat
    17401 aatgatccca gtgtccagat gttttgtaca actcaacatc tcccattatt ggtgtatata
    17461 catgttggta acctagacta acttctttgt ctacgatata acgttcgatc gtgcgtcgga
    17521 ttgttgcccc ttttggaagc cagaatggca aaccagaacc tacttctggg gaaaccatga
    17581 acaagtcaag ttcttttcct agtttacgat ggtctctttc ttttgcttct tcacggagac
    17641 ggatatattc tttcaaagct ttcttgtcaa aaaaggctgt cccgtataca cgttgcatca
    17701 tttgattgtt tgagtttcca cgccaataag cacctgccac tgataataat ttaaatactt
    17761 gtatacggcc agtggatgga acatgtggtc cacgacacaa atcgatgaat tcgccttgtt
    17821 gataagcagt aatcacttct tcttctggca attcactaat cagttctact ttgtacggat
    17881 cacttgcaaa aatttctaat gcttcctgtt ttgaaagaac acggcgttcg atcggcagat
    17941 tttctttgac gattttcatc atttctgctt cgattgccgg caaatcttct gcagttactt
    18001 ggttttgtcc attatctgta tcgtagtaaa accctgaatc gatagctggt ccaacgccaa
    18061 agtggatatt tggatagagg cgacgcatgg cttgggccat caaatgagct gctgaatgac
    18121 ggactaagcc aagtgcatct tcatggtctg gtgtgatgat ctcaatactt gcatcttcct
    18181 cgattggacg agtcaaatca acgagttttc cgttcacttt accagctaaa gctttttttg
    18241 ctaagctttt tgaaatgctt tcagcaattg ccaatgttgt tgttccagac tcaaattctt
    18301 tgactgcacc atctggaaaa gtaattttta tcataatagt ttcctccttg aaatgttttg
    18361 attgatcaga tcatcaagct gaaaaacaaa aaaatcctag catctcttga aaagagatac
    18421 taggacgaaa agttcgtggt tccacctaat gttcaaacgc aaatgcgttc ctcaagcgtt
    18481 gtaacggtcc gaccgccctt gcttcaacaa gggtttcgaa agtggtcatc ctttggtttt
    18541 ctcctggaaa agtttcagcc tagcttttcc tctcttatcg aagactctca aattcagttg
    18601 gctttctcat caatcaatta tgtgtttatt taaccactaa taaatagaaa aatcaagtgg
    18661 gaaactaaac ttattttttc cattccccat ttacaccgta tgttcctttt ttcatctcat
    18721 tgatgatgac atggatgtgt tcttttggtg cctgcgtgtt tttatgaaca gcttccgtga
    18781 tatctttcat catattttct aattgttccg gactgcgacc ttctactaat tcgacatgta
    18841 cgaatggcat aatgctctct cctctttctg atcgttcttt tttcaactcg attctatcat
    18901 actatgtttg tcttgggtac tgaatcagga aaaatggctg gatctttttt tgctctcaag
    18961 gcactcaaaa tagagaccgt atccacgact tcttgcaaaa cagctccgaa taatgcgggg
    19021 attagtcccg tacttgcaat taacatcaaa aaaatacaaa taaagatgcc aatcagtaca
    19081 gactgtttcg ctattctcat cgtatctctt gaaatcacta ctgcttttgc tacacgcaag
    19141 agatcatctt tcaagatgac cgcatctgca ctttcactag cagctgtaga accatgagcc
    19201 cccattgcaa taccgatatc tgcagcagca agtgctggtg cgtcattcac gccgtctcct
    19261 accatcgcaa caggtctttg atctttaggg atactttcta aaatggtcag tttatcttga
    19321 ggcaagctac gggcatgtac agaatctaat tggacttttt ctgcaatcgt ttgagcaatg
    19381 gcagatccat ccccggtgat catcatcaaa tttttcacat caagttttct tagctccttg
    19441 attgtctttg ctgcttctgg gcgaatctga tccgaaaata ggatcgttcc tgcaaaagat
    19501 cgatcaattg ttacatagat tgctgtattg gacgtttcta tttcttcagc tgaaacaaaa
    19561 gaggcacgtc caatctttac ttcatgatta ttgactactg cttggattcc ttgaccggtc
    19621 acttctttca gttgactaac aggatacagt tggctgtttt tcacgttgtt cactaacgaa
    19681 cgagctaaga tatggctaga ttcctgttct gcactagctg catacagaag tagctcttct
    19741 ttttttattc cattgactgg ctgaatcgcc tctacttcca atatcccttt ggtaagcgtt
    19801 cctgttttat caaaagcaat cgtttttgta cgtgcgagct tttcaatcgt tgttccagtt
    19861 tttacaacga tcccgttttt acttgaacgg ctcattcctg caactaaagc aatgggcgca
    19921 gctagaatca gtggacaagg tgatgccact accagtacct cagcaaatcg taaagggtct
    19981 tttgagaacc accaagaaat accaccgatc aaataagcaa tcaacgtgaa agggactgca
    20041 taacgatcag ctaaacggac aaatcgggca ggcttttctt ttgattcttc gactagttta
    20101 ataatcattt gatactggct gtctgcggca cgtttttcag cgatcatttg gatcgatccg
    20161 tctccattta aagaccctga cataatctga tctccaggtt tcttggtttc cgggcgggac
    20221 tcacctgtca aagaagattc atcgaccgaa gattctcctt tggtcactcg accatctgcg
    20281 ggtacaagtt cgccaggctt gactagtaac tggtcatcaa tatttatttc atcgattact
    20341 atatcctgca attttccttc tttgaatcga tgggcaattc ttggggtgtt atctaacaaa
    20401 gactgcagtt ctttacccgc tcgtttattc gcgtaatcct ctagactatc tccgcccgta
    20461 agcatgatca atatcatcaa actagcccag tattctttga cggctaatgt tgcaaggatt
    20521 gcggtaatcg ctaatacatc tacgccatat cttcctgaac gtaacgtctt gatcatttcc
    20581 aaaaacatca agaaggcgag aatccctcca gtaaatgcga caatcgcaaa tgcaagggcc
    20641 ggctggtgaa aaacaaattc acttaataaa gctatcccac caataagcaa agtaagtaaa
    20701 aattttttga aatgtgtcat tgttttttct cctcttttat gtgacttaga gaggttagta
    20761 ataaatttcc agctgcctct ttcatcttaa gcatagtcct tgactagcac tttttaaaac
    20821 aataggcctt aattgaaaac aactatcact atcagcgttt ccaaaattca tcagttctac
    20881 aaacaaaaat attcagcaag gattactttt tcgattcatc agttaaaaag tacctttttt
    20941 cgaaaaacta tgctatactt ttaattcgtt atttacggcg gaaggagcaa acatgcgatg
    21001 aatgagaaac aactagaaca aacgcacgtg gatgaaacga tcgaactaat ccagatcgaa
    21061 caaaatatgc tggatacaaa acaacaagaa ttgactcagg aaatgaatca ttcgacaaaa
    21121 gacacagcta atcacaagat tcgagctggt tccaatgaag ctttttatga atctgctgtt
    21181 gaatatcgcc aacatgagca ggaattgctt ttgaaatacc atactcttga agcacagcaa
    21241 aaacgcctgc aaacgttgtc tgtcatgaaa gatagtcctt attttgcccg tatcgacttt
    21301 aaagaagacc gtgaaacaga aacattatat ctaggtatcg cttctttaag agatctggca
    21361 gaagaaacaa tcgttattga ctggcgcgca ccaattgcca atctttatta tgaaggtgag
    21421 attggtcccg cattttatga aactgaaaca gatagaatag atgtcgatct gcagttgaaa
    21481 cgacaattta aaatccaaga aggacgtatt ttatctatgg tagatacgtc ggaagtaatc
    21541 aatgatgact ttttgctaga gatattggat gaatcatcaa gcaaccatat gaaaaacatc
    21601 gtctctacga tacaaaaagc acaaaatgca atcattcggg acacaacaag taaagtaatg
    21661 ctgattgaag gaatcgccgg aagtggaaag acatccgctt tgcttcaacg tattgctttt
    21721 ctgttgtatc ataatcgcaa gtggctcgag gctgaaaacg ttcttctatt ttcacccaac
    21781 catttgtttt ctgattacat ctcgactgta ttgccttcat taggtgaaag cggcgtgcct
    21841 acacagacat tcaaaaatta tttggtgcag ctgctgccag agttttcttt actagatgaa
    21901 cagcaacaag aaagtggttt tttgctaggg gaaaaagatc cgatacaagt gatgaaaagc
    21961 ggattgacct tagtcgatca gattgatcgc tatatccaag gcatcacaaa ctacggtccc
    22021 ttgttccgtg atatgaaaat aaatggccgt acgatcctat caaaggaatc gattcgccaa
    22081 tggtataaag aaacaaatga acaattacct ttacatcata gactttctct attacaaacg
    22141 aagctcctga aaaaattagg cggtctgcaa aaagacgaaa cacgtcagca atgggtcaaa
    22201 gatctggcgg aagaacagct ccaagaacta tacgcaacag atccaaatct tgaatataca
    22261 gaacaaaagg agcgttcatt acgtaaaaaa ctggccaacc aaatcgtacg taaaagattc
    22321 cgtcgaatcc atcgagggat catgaattat caatttgtca atataacgaa acaatatctc
    22381 cactttctac aaactgtgcc actttctctt ctaacacgac ataaaatcag cgagaccagg
    22441 tggcaggaac atttgacaac tgttcgtaca cacttgcgtc aaagagaatt gcgtcaagag
    22501 gatgctgtac tattcttttt actgatgcgc cgaacatatc cagtgacggt tacacacaaa
    22561 gctcgctata tctttattga tgaaatgcag gatttcgcac catcacaagt ggcattgctg
    22621 caagccttgt tcccaaaagc aaatttgact ttctgtggag atctaaatca aaatgtcttt
    22681 ggaaatgaaa cgatcgttgg atcattggaa gaccttttcg tggaccgtga agtcactcgt
    22741 ttccaattaa cgacaagcta tcgctccaca aaagaaatca ctgattttgc taatcatttt
    22801 attgtgaaag aacatcaagt agaaacaaca gcaagaaaag gagaccttcc tttgctcatc
    22861 caaggaacaa cagatgatat caaattgaat tggttagcag ataccattcg aacgactcag
    22921 ggaaaagccc ggtattggcg tacagcaatc atagctaaaa cacaagaaga atgcgaagct
    22981 ctttatgctc aactgccaga cgagttgaaa caacaagtcc agctgatttt aaatgagagt
    23041 gactttatga agcgttccat tattttactt ccagcctttt tagcaaaagg tctggagttt
    23101 gaccgagttt tcttgtggga tgtagatgca gaacattttt cttctcagca agacaaattg
    23161 atcctttaca ccatgtgtac acgtgcgatg catgaattga ccctttttac ctccaataat
    23221 gaaagtcctt tgttaaacaa tatggatatt tcatcttatg agaaaaaagt actgtaagta
    23281 aaaagacaac tgctatcatt aatgttagca gttgtctttt tatttacaat aataattgca
    23341 gaaaaagtaa ttcaatcatt taaggtcatt tattctatat ataaatccaa atctgtttca
    23401 ggatatttta atttgacaag cgaaataatc attttcagtt cttccatgtt ttctggatat
    23461 tctgggtcaa ataccttgct atgacggcca atcccgccat tgtcgatcaa tcggtaaatt
    23521 cgattccatt caatgaattg gtcaattgat tggaaattgc tgattggata gccgccacaa
    23581 tccaaaatct ctgatacacg aaatgctagg tatgcactat cgatcacttt attttttttc
    23641 gtgtctatct tctcatttct ttcgataaga attttttcag gacgatgttt caagctccac
    23701 tctaatagta gaaagaaagc ctccatccga tactcttctt caaataaccg aaaggctgaa
    23761 tcagaacgac gaaaaagcag cggaatcaga taattttgtc tataaatcag cattggtgcg
    23821 cggtccacca tacactctaa ataacggttc agataccctg taccgacata gtttcctaat
    23881 cgatagcctt caacgccgaa tcttgcgtat ttttgcgcta attttgaaca atcagttacg
    23941 ttcacagcta actcttctac tttgcggtaa ccgcttaaga tacgttcaaa aggttctaaa
    24001 gtgatttttg cttccatatt cttccccgtc catcttccac atacttcata tcatttcaca
    24061 tgatacttat gctctcatca taccacaggt tgaattagaa aagaaaataa atcacacaaa
    24121 aaagcaagac aatctgttag tgagattgtc ttgcttttcg aaaaagactg aatacttttc
    24181 gttaaaactg gttgcttagt cttctaatgc cacattatgg aacacatgct gtacatcttc
    24241 tagatcttcc agtgcatcaa tcattttttc aaatgtttct tgatcttctg gagatagtgt
    24301 tacctcgttt tgagggatca tttggatctc agcgattgaa aaatcagtga ttcctttttc
    24361 ttttaatgct tcttgtatac tatggaaatc cgctacttca ccgtaaacga tgatttgtcc
    24421 ttcttcttcc attacatcgc gaacatcgat gtctttttcc attaggtatt caaggatctc
    24481 gtcagcgtct tctcctgcaa aagcaaagat tgctgtattg tcaaacatgt aagaaaccgc
    24541 tccggaaaca cccatgttcc cgccattttt cccaaatgct gcccgtacgt ctgctgctgt
    24601 tcgattcaca ttgttcgtca atgtatcaac aatcaccatt gagccgcttg gtccaaatcc
    24661 ttcatagcgc aattcagagt atgtttcatc tcctgcacct tttgcttttt cgattgctcg
    24721 gtcaataata tgttttggta cattataagt tttagcgcga tcaatgacga aacgtagttt
    24781 ttggtttgca tgcggatcag gatcacctga ttttgctgcc gcgtagattt caatcccaaa
    24841 ttttgcataa atccggctat tattagcatc tttagcagtt ttctttgcta cgatatttgc
    24901 ccatttacgt cccatatttt cacttcgctt tctgatttga tagtttcata acgcaaaaac
    24961 gtcctgttcc attatacttg tgaatcacga ttctgtgaag ctttttttct ttcttccttc
    25021 attcttctca tttttagtca attatctata ctcggattgg gatttgcccg aaattctgtt
    25081 ccggaatatt gcctcccaat tgatagattt gatcacttct aactaacagt tccgcttctt
    25141 gtgcctcttt ttttccgatt cgggaataaa tagaaatctc ttttttttct tttaagaatc
    25201 ttcttccagc atcggtaaat ccaagtagtc gaagataatt tttattttgt tggacaggaa
    25261 tctcttgctt tttgatattc agcaagacat aacaagataa tcgttggatc cgtgtccatg
    25321 tatatctttt tgtttttacc tttgacacaa aatcctcaaa actatcagca gttgcagctg
    25381 ctgttttcat gcgcgattct attccttcgg tcatctgata gatatctgtc agttccagca
    25441 aagtagaaga taacaaccga taacgcaaat acggccaata agattcccaa gtctgcagcg
    25501 aacaagttga aagatcttct tctgtctgag gcggcacaag tccagctatt ctttttcctt
    25561 cttctaacgc atggcgaatg gctgttgcac tggctatcct ctgatctgtg atgatttttt
    25621 catgatagcc tgcactttta cgtcggatcg gatgtaattc catagggtgg acatacttgg
    25681 cattttcctt tgcataactt aatcccaaga tatgatttgg cgaagaaaaa tcaagcgtaa
    25741 tatcgggata cagactgcga aaaacctcag tcattttttg cggataacta tacgtttgat
    25801 cagacagttc ttgaaatgcc tcttctatcc tatcttgatt ctcttggaca aagcgtccga
    25861 aactgctgta atcaaacgaa gtctcttctt ctgttccaaa acacaaactg tcacagtcca
    25921 gtgtttgcaa gatttttact gcacctttag caaaatagtc agctgactga accgcccatt
    25981 cgacgggaag ctccactact aaatccacac cattttgtaa agcttcattc gcgcgatgcc
    26041 atttatcgat gatagccggt tcgcctcttt gcaaaaaatt cccgctcatt acagcaatga
    26101 cgacctctgc tcctgttatt tttcgtgcca tttccacatg atagcgatgt ccattgtgaa
    26161 aaggattgta ctctacgata atcccgcagc ttttcatgcg catcctcctt catagttatc
    26221 gataaaaaag aaatagagac aagtaaaaaa aggcaaaaat cggaaaaaat acccgaacta
    26281 tataaactat tctcgcaaac acaatacttc tgcgacgaaa agctgcactg caagagcaat
    26341 gcctatatcg ttcggatata taatttatgt tgaagattta ttcttttctt gttaactcga
    26401 gcaggcaaaa ccgctagtct ttgtatgcta caaagaacca gcgctttgat ttctctgatg
    26461 ctgcttcgtc tgtaaaatca gaaaatgctt cgactttcga aaagccgctg ttttccagca
    26521 ttcttaaata actttccaat ggataggtac gctcttgatg tagttcatct tcacgaataa
    26581 atcgaccaga cccttcttgt tcttcaacga aaaaggtaag aaaatgttcg atgctgtgtt
    26641 tctcgcttcc tggataacta tcccacaaaa aagcaaaatt atccccttga taatgatagc
    26701 tatattctgg aaaaacctca tctacttgat aggtggagtg tacgtcaaat aaaaatcggc
    26761 cattttcttc taacgcttga tagacttcat caaacacttg ctgtacctct tgtctatttt
    26821 tcatatagca cagcgaatca gaaaaacagg taattgcctg atattgtccg atttctgata
    26881 aatcgagcat attgccttcc acaaattgga tcgatgcgtc ttcttcatat gctcgctggc
    26941 tggcaatcat caacatctct tctgaaaggt ctaaccctgt cactttatat ccatcttttg
    27001 caaaggcaac cgctaatgct ccagtaccgc atgccagttc caaaatattt tttgtgtctt
    27061 cttgtaaatg acgtttcgaa aaagctaacc attgctgata aagtgtttcg tccatcactt
    27121 catcgtaaat gaaagcaaat gtttcataag ccatatgtta atccaaccat tcactaagat
    27181 cgactagcgg agcatctgac catagttttt ccagattata gaaatttcgt tctggcgcat
    27241 ggaaaacatg tacgatcaca tctccaagat cgatcaatac ccattttccg ccttcttttc
    27301 cttcaatacg ttttacttca tatttgtttt cttcttcttt atcaatgatt tcttctgtaa
    27361 ttgcgttgat ttgacgttcg ctatttgctg aacagatcat gaaataatct gccaacaagg
    27421 aaacatttcg aacgtctaaa gcgataatgt cttctgcccg ttttgaatct gctgcttcaa
    27481 tcgcaatttt taattgttct ttactatcta tgatgatttc ctcctaatat gagcagctta
    27541 tttttttgct acccagtaat tatatgtttc gattgttttt ggataaatct gttgttcttg
    27601 cgcaagcaaa tgggccaatg tatgttttgt ttcaaatgct acagcttcgt ctagatcagc
    27661 ccatgcaatg gctcgtgcat cttgtacccc aggaaaatct cgacctggtt caatatagtc
    27721 tgctacataa atgattttgt caaggagact catcttagca gccccagtcg tatgcacccg
    27781 gattgcatga agaatctctg catcggtgat tcctaattcc cgctctacaa acgaagcgcc
    27841 aacaagacca tgccagattg cattattata attcaataac tccggatcaa aaccgtctct
    27901 tacgattacc attttgaact cctcatctgg tcgttctttt gcataatcat gtgtcaatgc
    27961 agcaatacta gctttttcag gagaagcacc gtattttttg gcaagagcca cggctgtttc
    28021 ttctactcca agcacatgct tgaagcgttg ttcgctcatt ctcatctgta ttttttgcat
    28081 caggttttct ctagaataag cagtatattc attactatag tccatattca tacaaccctt
    28141 cattttgaat ataatcaatt actttatctg gaacaaggta gcggatagaa cagccttctt
    28201 tgatcttttg acgtattttc gtggaactga tgtcgatctc aggtacatct acccaaatta
    28261 caggatatgg agtatccgtt gtgtatcctg gtcgacgtat acccacaaag ttgaccatag
    28321 aagtcagctc atcgatttta taccattttg gcaaatattc taccatatcc ccaccgataa
    28381 taaagtaata atctgtatcc ggattgtttt gcgtcaattc cttcatagta tcataggtgt
    28441 aacttttccc accacgagct aattcaatcg tttcaatctg caaaaaagga ttgtcttcca
    28501 ccgctaattc caacatgttg agtcgatgtt ttgcatcaat cgtctgtttc tcatcaacat
    28561 gaggtggctg ataagaaggc atcaaaaata cgcggtcaag acctaaattc cggccagctt
    28621 gttcagccat cactaaatgt gcaaggtgaa cgggattgaa tgttccgccc aagatcccta
    28681 cttgcttttt cttctctaag aattgaggca tttcttcagg aaataattgt gaacgaacaa
    28741 atgtcttagc ttgcgtattc atcatggtca ctccttatat tgcttttact tcttttgata
    28801 gcctttgata cttttctttt gtggaaggtt tgtataatac aataacacgt ccaatgattt
    28861 ggacgatttc gcaatctatt tctttttcta atacttgagc tgcttcttct gcaatctcat
    28921 ctgtattttg aagtaacgat actttgatca gttctctttt ttctaaagct tcttcaattt
    28981 gaacgatcat tgctgaattg atcccacctt ttccgatttg aaaaatcggc tgaagatgat
    29041 gcgctttgct acgtaaaaaa cgcttttgtt ttcctcttaa actcataatt ttccttcttc
    29101 cttaaatcaa tgctttgcgt ttcaatacat ctacaccctt tggcgcccag cccgcaatta
    29161 ctactggcgc tgttacagtg atccagccta gaccggcaaa aacgatgtct gttttttctt
    29221 tcacagaaaa ctcaaaacga acaagctccg gaaatgcctc gacttcatca ggacgaggag
    29281 gctgtaataa tccacctaca tgtttttgat aaaattcgtc tgctttttcc agtttcgttc
    29341 gatgaatatt tacatcattt gacacataag caataaatga agcacgattg ccgctgataa
    29401 aatcaaatct tgcaagtccg cccaagaaaa gtgtttgccc ttcattcagc tgataaactt
    29461 taggtttgat ttcttttaac ggtgcaatga tccgcaaatc ttttttacct aagtagtgcg
    29521 ccatttgatg gcgatggata attcccggtg tatcaatcaa aaaatgcccg tcatctaaag
    29581 gaatctcgat tttatccaag gtcgttcctg gaaactgcga agttgtgatt acatcttgta
    29641 ctcccgctgt atttttgatg atttgattga taagcgtcga ttttccgaca tttgttactc
    29701 cgacgatata gacatcccgt ccatcgcggt attcttcgat tttttctaat agttccgtca
    29761 tctcatgaga tttcttagca ctagttaata atacatctac tggacgaatt cctgcttcgt
    29821 aagcacgttc cttcatccat tgtgttaatt tagttttttt caatgattta ggtaatatat
    29881 ccactttgtt cccaactaaa agtactggat tgtcaccgac aaaacggtgt agtcctggga
    29941 ttagtgaacc attgaagtca aaaatatcca ccacattgac gatcaatgca tctttttgcc
    30001 ctaattcatt cagtaagcgc aaaaagtcgt catccgtcaa tgagacatct tggatctcat
    30061 tataatggcg taatctgaaa caacgctgac aatagacttc cccggaagct aaaccttttt
    30121 ccaaagccgt ttgcggcgtg tatcctaatt caccgggttt gtttgtttgt ataacggcac
    30181 cacagccgat acattgtaat tcttctgtca ttcgattcca cctcgccagc ccatatcagg
    30241 gtgttttgct aatagatagg ccataattct tttttcccaa aaacgattaa attgtgtctt
    30301 ccaactatct gttgcgataa tgggttttac aaggatgcta cgtatccctg cacgattggc
    30361 tccacgtata tcagtcataa tctgatcgcc taccattact atctcatcat ctgctaaatc
    30421 caattgtttc tttgctatgt tgatccctct tgctaaaggt ttcattgctc gtgcaacata
    30481 caaaagatca aatttttcaa tcgctcgcgc gacacgtttt gaattattgt ttgaaacaac
    30541 aacaacaggg attcctgcat ttttcatttc taaaatccaa gtaagcaact cttctgttcc
    30601 atctggatta ttccatgcaa tcaacgtatt gtctaaatcg gtcaatactg ctttgatgcc
    30661 tagattcttt aattgggcag gtgtaatctg atagatggct tctaccatcc atgttggttt
    30721 gtaatttgaa aacatgctgt ctcctcatct gcaaaaaatg aaggagcaca taaagtactc
    30781 ctcaaccccg tattatactg catatcagca aaaaaaacta cctctatact cgttcgtctt
    30841 tcagaaaaag catttcttta caaaatgacc aaaaataaag attgatcaca gaaaaattta
    30901 gaaacaaaaa acaactaata ttggcggaac ctcttgtatc gtttttccag taatttatgc
    30961 tgatctaatc gaacaagttc cgtcaatctt tcaatcaacg cttttttcat aatgtgtgcg
    31021 actttatatc gtggcaactg ctcgccgttg aacgtttcag gaataactcg atcaacgatt
    31081 cctaactcgc gtagttctgg cgcagtaatt ttcatcaact cagctgcttc tgcggcgcga
    31141 ctaccgtctt tccacaaaat cgacgcaaat ccttctggag aaagcacagc ataaatcgtt
    31201 tcttccagca tccagacttc atccgctaaa cctagagcaa gggcaccgcc acttccacct
    31261 tcaccaatga tgatggcgat gatcggtacc tttaaatcag acatttcgag cagatttctg
    31321 gcaatagcct ctccttcgcc gcgctcttct gctcctacac cgcaatatgc acctgctgta
    31381 ttgatcaagg taatcaccgg tctattgaac ttttccgctt gtttcatcag tcgtaaagct
    31441 tttcgatagc cttcaggatg gggagaacca aaatttctgc ggatattttc ctgcagatcc
    31501 cgtccttttt gaataccgat cactgttacc ggtttgccat ctaatcgagc gattccacca
    31561 acaatcgctt cgtcatctgc aaataaacga tcaccatggc attcctcgaa agaatcgaag
    31621 atctcttcaa aaaaatccaa gcttgtccat cgttctttag ctcttgctaa ctgaacgaca
    31681 tcatgtgctg tcttatccac gatctatcca tcctttctgt gtatgcaatt caagaagcgt
    31741 atggattttc tgtttcaatt ccatgcgggg aacaatctga tcgacaaaac catgagataa
    31801 taagaattca gccttttgga aatcttctgg aagttcctgc ttgatcgtct gttcgatgac
    31861 gcgtcttcca gcaaaaccga tcaagctttg gggttctgct agaataatat cgccttccat
    31921 tgcaaaactg gcagttactc ctccggtcgt cgggtccgtt aaaacagtta gataaaaaag
    31981 accttcattg ctatgccgtt tgacagcagc agagattttt gccatctgca ttagagaaaa
    32041 gattccttct tgcatccgtg cgccacctga agctgtgaac aagacgactg gaagactttc
    32101 ctttgttgct cgttcgaata atctggtgat cttttctccg acaatcgttc ccatacttcc
    32161 catgataaaa ttaggatcca tcactccaat aatgaaggga atcccctgaa tggttgcttt
    32221 accagtgagg actgcttcat gaagtcctgt tttatcttgc atttttttaa ttttttccgt
    32281 atattcggga aatgctagcg gatctttggt tacaagatcc gtatcccatt cttcaaaact
    32341 tttttcatca ataatcaaag ctagacgctg ccatgcaccg attcgaaaag cgtatccgca
    32401 atgagggcat actttttctt caccgatgtc tttcgtataa aggatatgtt tgcaatttgg
    32461 acactttgcc cacatgttat caggaacaga tggcgagtta gcaggtttgc tctctctatt
    32521 aggattgatc cgaatatatt tctttttctt aaacagagcc atctatgcgc ctcctatctc
    32581 cgtttctggt gtccaattcg gtaaaaattc ttcttgtaaa aatgctgtgc tgtaatcacc
    32641 tgctatgact gcaggatgac taatcaaatc catctgaaat tctgcgttcg tgatgattcc
    32701 ttctgtgata aattcactta aggctcgctg catcttcatt aatgcttcaa aacgcgtatt
    32761 tccatggacg attatttttg caatcattga atcataatat ggcgggatcg tatatcccgg
    32821 gtaaactgca ctgtctactc gcagtcccat cccacctgct ggaagcagta agttttggat
    32881 cttccctgga gaaggagcaa aatggaaagc aggattttct gcattaatcc ggcattcgat
    32941 tgcgtgtcct tggaatacta cttcttcttg acacacattc aaaggctcac cggctgctat
    33001 ctccacctgt ttttttacta aatcgattcc tgtgaccatt tctgttactg gatgttccac
    33061 ttggattcga gtattcattt ccatgaaata aaaatcgcct tcttcatcca tcagaaactc
    33121 gatcgttccg gcattttcat aattgactgc tttagctgct cgaacagcag cgtctcctag
    33181 tgcttctctt tttgtttgtg agatcactac agaaggagat tcttccagta ctttttgatt
    33241 gttgcgttgt aaagaacaat ctcgctcgcc taaatgaatg acatgaccaa atcgatcacc
    33301 taagatctga acttctatat ggcgagcagg ataaatgatt ttttccaaat acatatcatc
    33361 atttccaaat gccgctgctg cttcttgctg agctgaagaa aaatgctgtg ggagctcttc
    33421 ttttgattga actttccgaa tgcctttccc gccaccacct gcagctgctt tcagcatcac
    33481 tggataacca attctgtctg ctatttccaa tgcttcttct actgtagata atacaccagt
    33541 acttcctgga atgactggga catttgcttc ttgcatcaat tgacgcgcat tgatcttatt
    33601 tcccattgca tcgatcgttg cacttttagg accaataaat gtgatattgc actcttcaca
    33661 catggaggca aatcggctat tttcagataa aaaaccaaat cctggatgaa ttgcttcggc
    33721 ttttgtcacg attgcagcgc tcagtacttc ctgaacattc agatatgaat caacggcttt
    33781 tgccgggcca atgcagattg cttcatctgc taactgtgta tgaagtgctt cggcatctgc
    33841 ttctgaatat atcgctacgg tttggatccc tagttcgcgg catgcacgaa tgatacgtac
    33901 agcgatttca ccgcggttag ctatcaatac tttagaaaac atatttcacc tatccaatca
    33961 taaaggttaa ttccgcttcg gctacttttt taccgtctac tttagcgatt cctttgccta
    34021 ttccggctga agctttcact ttcaatatct caacttcaag gtataaggta tctcccggtg
    34081 taactttctt acggaatttt gctttgtcca atccgccgaa ataagccgtc tttcccttga
    34141 attgttcaag agaaagtaat gcaactgctc ctgcttgagc cattgcttca acaatcaata
    34201 cccctggcat aacaggttct tctggaaaat gtccttgaaa aaagggctca ttgatcgtta
    34261 catttttctt agcaacgatc cgttctcctt caaccatttc ttccactcga tcaatcaaaa
    34321 gcattggata acgatgtgga atgatttctt ttatttcttg tatgttcatt gttttccctc
    34381 tttcctgctt tgcttatttt tgctgaatcc taaagagtgg ctgtccatat tcgacaactg
    34441 actcgttttc tacaaggatt tctgtgatca ctccgtcggc ctcactagtt atctcattca
    34501 tcagtttcat cgcttcaata atgcagataa cttctccttt ggcaacttga tcacctactt
    34561 ttttgaaagc tggtttgtcg ggcgctggtt gcagataaac gattcccacg attggcgaaa
    34621 caacctcgat tccatcaaat actgccgatt ctttttcttt cattatttct ggagcagttg
    34681 ttgcttgttc agatatgaca ttgactggct ccgaaactgg caacgtttcg tttgtttgaa
    34741 ccatattcat gcctcgactt gttttatttt tattcatata caattcaaat tgaccttcac
    34801 gcaaatcgaa ttccgttagc gaggattgat caaattgact gactaattct ctgatttcat
    34861 tgatatccaa aattattcct cccagcgttt catgcacaga accgcattat gtccgccaaa
    34921 ccctaatgaa ttactcattg cataagtaaa acttgcaggt ttgctttcgt ttttgacaac
    34981 tgtcaagtca atctcaggat cttgtttttc tacattgatc gtaggtggga taaattgatg
    35041 ttctaatgcc agcaaagttg ccaaggcttc gatcccgccg gctgctccca ataaatgtcc
    35101 agtcatcgat ttcgtgctgc tgacgtaagt atctctgaaa ttttcaccta atgcgatttg
    35161 gattgctttt gcttctgcct ggtcattggc tggtgtactt gttccgtgag cattgatata
    35221 tccgacttgt tccggctgta caccagcttc ttccatcgca agcttcattg ctttagatgc
    35281 accagaacca tctggagtag gagctgtcat atggtaagcg tcacagtttg caccgtatcc
    35341 aacgatttct ccatagattt tggcaccgcg agcttgtgca tgttctaaag attcaagaac
    35401 tagaacgcct gctccttcac ccatcacaaa accattccga ttttcgtcaa acggaatcga
    35461 accacgatta ggatcagttg attctgagag tgctgttaaa gctgcaaatc cagcaatccc
    35521 catctcacaa atcgttgctt ctgttcctcc agcaagaatg acatcagaat agccatgttt
    35581 gatgttacgg aatgcttccc caattgaatt cgttccgcta gcacaagctg ttacgatagc
    35641 tgtacaaata ccttttgcac ctacacgcaa agcaatattt ccagctgcca tgttggcaat
    35701 cgccattggt acgaacattg gagaaactcg ttttgcacct ttttcatgta gacgaataac
    35761 ttggttttcg attgttggaa gaccaccgat cccagatccg atgatgacgc caaaccggtc
    35821 ttgattcatt ttttctttat ctaaaccgct catctccatt gcttctaaag cagcgtagat
    35881 tccatagatc gaaaacatat ccattcgttt gctatctttt ttaataaaat atttatcgta
    35941 agggaaatct ttgacttcac ccgctaaggt aatccctgtt tctgaagcat caaatttagt
    36001 gatcggtgcg atgccattcg tcccctcttt taagctattc aaaaagctgt ctgcgtcatt
    36061 tccaataggt gaagtgactc catagccagt aattaccact cgattcattt gtttgctctc
    36121 cttttcttat ccgtgcatga ccaatccgcc atcgacattg atgacttgtc cggtgatata
    36181 tggattttgt gctaagaaaa ctgctgtttg tgcaatatct tctacttgtc cgaaacgctg
    36241 catcggaatt tgcttttccg cttgttcctt gactttgtct gctaaaactt ccgtcatatc
    36301 agttgtgatg aatcctggcg caatggcatt acatgtaatg cctctagttg cagcttctcg
    36361 tgccacagat tttgttaatc ctactacgcc agctttacta gctgcataat ttgcttgacc
    36421 aatatttcca atcaacccag atacactaga gagattaatg atggcccctt ctcgctgctt
    36481 catcattttt ttcaatacgt gctgcgtcat attgaaggtt ccaatcaaat tgatatccag
    36541 acattttttg aaatcttctg catccattcg catcacaagt ttgtcatttg tgattccggc
    36601 attgtttact aacacatgga tcgatccaag cttttcttct gcttctttga tcatttgtcc
    36661 cgctttctca taatcagaga tgtcaccgga aactcctacg cattttacac cgaatgcttc
    36721 gatttcttct atcttttctt ttggaatctc tccgcgacca ttcaaaatga tatttgctcc
    36781 agcttttgca aaagctaagg ccatcgcttt gccgattcct cttgtactac ctgtgataaa
    36841 tacatttttt ccttttacat ccataacgtt cctccttata gtattgctat tgtttcatca
    36901 aatgtctgct tattctcaac acgcagaact ggtattgttt tatcgatttt tttcataaat
    36961 ccgcttaata cttttccggg gccgacttcg atgacttgtt cgatgccgat tgtttttaac
    37021 ttatggatac tctcatagaa acgaacaggt tgcatgactt gctgttcaag tagtcccgcg
    37081 attgtttctt tcttcattat ttccgttgtt gtgttgctta tgataggaaa agaaggttca
    37141 gagaattgaa tctgacttag gtccttcgcc agtttttttg ctgccggttc taaaatagct
    37201 gtatgaaaag gcccgctgac atttagaggg atcattcttt tgaacccttt ttcttttaat
    37261 agtaaaacag cttcgtctac tgctttttct tcgccaccaa tcacgatctg ctgaggtgta
    37321 ttataatttg caggagatac gatgccgtac ttgctagctt catgacagct ttcctcgatc
    37381 gtttcaatcg gcgcattcat cactgcaacc attttcccgc ttccagctgg ggtagcttct
    37441 gtcatataag cgcctctttt tgctactaac gcaactgctt cagtgaagga tagcgcatta
    37501 ctagctacta atgccgaata ttctcctaaa ctcagtccta aagctgcatc tgggatgatt
    37561 ccatgctcct tcaataagcg ataatacgcg atgctgactg ttagaatagc tggctgtgta
    37621 tattgcgtct gatccaaacg ttcattttct gtaaagcaaa gttcagccat atcgtagccg
    37681 agaatctcac ttgcttcatc aaatgtctgc tttacaacgg cttcttcata taaatctttt
    37741 cccatacctt gatattgtgc accttggcca ctaaataaga atgctgtttt catgtttttc
    37801 tccaatatat ccagaatata tgtttgattc ttcctattca aaaaggccga gacattccta
    37861 tttcaggaaa tgtcccagcc cccaacctaa ttttaatgat tatgcagttt gtttttctac
    37921 gtaagtcact aaatcttgaa ccgttttgat tccgtcttct gtttcgattt tcacgtcaaa
    37981 ttcatcttca atttcattga tgatttggaa taaatccaag ctgtcagctt ctaagtcttc
    38041 ttggatgtca gtagtcaatt tgatttcttc agtttctttt cctaattctt ctgcgatgat
    38101 ttcttgaatt ttttcgaata ccataataat atattcctcc gatattgttt gctttttatt
    38161 tttataattt aacagtctac aactccatga gaatacttcc ccatgttaaa cctccgccat
    38221 agcctgtaaa tattactttc tgctgttttc ctaaggtgat ctttccacta gaaactgctt
    38281 catccaataa gatagggatg cttgcagcag atgtattccc atatttatcc atattggtca
    38341 ggaacttttc ttgcggcatc tttacttttc gggcaatttt ctcaataatt ctgaggtttg
    38401 cctgatgcaa aagcagataa tcaactggtt tgtctttcat gacttcttgg atattgtttg
    38461 caacgtctcg tacggcaaaa tcaaaaatat ctctgccagt catttgcaaa taatacgaac
    38521 cttctgaatc ttctgaatag aacggatttt tattttgctg gtagccagcg gtcaatgagc
    38581 tacttctggt accgtcagct gctaattttt ctttcagcaa ttttttctgt ggattcgctt
    38641 ctaagagaat cccacctgct ccatcgccaa acaacacagc agtcgtacga tcagaccaat
    38701 cgattagctt agatagtgtt tcaccaccaa tcaccagtcc cttagttgag ccgcagcgga
    38761 tcattttttc agccatgctt aacgcataaa caaatcctga gcacgcagca ctgatatcaa
    38821 aagcgatagc atgagttgct cccaatttcc cttgtacttg tgctgctaca gatggtgtcg
    38881 tgtaatcggg cgacattgtt gctactaaaa taaaatccaa atctttaggg tttagatttt
    38941 tctgttttat caatttttcc gccactaaaa tgcataaatc agaagtctcc tgatttgtta
    39001 cacatcttcg ttcacgaata cccgtccttg acgaaatcca ttcatcagag gtatccatca
    39061 tcttggaaag atcattatta gtaataatct tttcaggaag gacgctggct gttgcagtaa
    39121 tcattccaaa ttgttccatt aaatatcctc acttatagtc ttgcaagaag tcgtgcaagt
    39181 ttttcagtgc atccagcaag gcatgctgtt cctccgtagc cattccgtct aagatgttct
    39241 tgaccatttc acgatgaaaa tgctgatgga cccgaaatag taactttcct tttttcgtta
    39301 gtcccaactt tacaacgcgg cggtcatctt cactgcggat acgttcgaca tagccttttt
    39361 ttactaactt gttaatagca gtggtcaagg tcccaacagt aattgatagt tctttggcta
    39421 cttctgaagt tgtttttttc ttgtacatcc cgattgcctc gatcgtgtgc atctctgtga
    39481 ttgacagatc tttgaattga gattttttca gctcagactc ttcgattgtc aaaatatcat
    39541 tgaagacact aacaagataa tcatttactg tttttaaatc tggttccatg ttccaccgtc
    39601 cactaattag tttgattatc aaatcttttg atgttcaaac tatatcttaa cttttttcaa
    39661 aatgcaacct taaaagatca tttttttact atatgagctt tttttaagat tttactcatt
    39721 taaaacaact gataaatcag catttataat ttcttttatt agaaaaatca tctatctcac
    39781 atattttgat tatcaaagta ttttctgtga acagaactat agaattccct aaaacttgtc
    39841 cattatttca aaatttgtta tagtcttttt attcaaagcg taaaaggaga tcctatgtta
    39901 aaagaaaaaa tgaaaactct ccccatgctg ccgggtgtct atcttatgaa agaccgagat
    39961 ggtaaggtca tctatgttgg taaagcaaaa cggctcaaaa atagagtaag cagctatttt
    40021 catcagaata aacagcattc aaaaaaagta ttacgtatga ttcatcatat aacagatttt
    40081 gatttcgtcg tagtagacac ggaattagat gctttattgc tcgagtgtca attgatccaa
    40141 cattaccgtc ctttttataa ccgacaaatg aattatttca gtaattataa ttatgtacat
    40201 attaccaata agggatttgt attaacagat actcctacgg ctcgaacata cgggcctttt
    40261 cgtctctata aaaaaatgcc gtctattttg cgtataatgg aagaaactta tcaaatgcct
    40321 tggttgtctg aaattagttt gttagctttg cgagtccagc ttcctgacct acaggaaatg
    40381 acttttgaac agaaaaaaaa ggaactccaa gggctgtttc aaggccgaaa taaaaagcta
    40441 ctgacttact tgaaaaaaag acaacaacat ttcatctatc agttgaattt cgaaaaagcc
    40501 ggtatgcttc aaaaagatat cgaattagtt acttatttta ttagacggat ccaggaacaa
    40561 aagcagtttt taagaacacc atcgctcacc ttcagcatgc cattagcagc agatgagagt
    40621 cagaaaaagc actacctcgt ttgttatggt caacttgcag aaacaatgat tacctctggt
    40681 gacgtttctc ctgacttcta ttatgaaaag aaagaagctc atttatcttt gaaacgtcaa
    40741 ttgtcaaaag aagaaatcga tcctgtacaa atcttgatca gttaccgcaa aaaattagaa
    40801 aaagaacagt ttgaaattga actgttaaac aaaaaagaag ctgaaaagca actaaattag
    40861 ttgcttctcg gcttctttta ggcatcttca acttcaaatg tcaattatcc taaaatttat
    40921 tggattaagt catagatttc catcgctacg atatcgatat tatcaaattc gtattgctga
    40981 tgagtatctg tttcagttaa ttcaaatgta tcggtcgctt tatcataagt tactgtacac
    41041 ttctctacgc cttctttttc aaaacggcga acttgcagtt cattatctgc tgactcgacc
    41101 atagcctcca gtcgttttat gattgcgact aattgtgaat gtgtcatcgg aggtcctcct
    41161 tttcttattt ctgttatatt gtatcaaaag catagcctac ttgcattgat tttctctaaa
    41221 aaaactcgtt ttttatgatt ttttttctgg tatttttcct tcaggccacc aaagtttgat
    41281 caaagcttgg gttccgtcat tctcaaaacc tttatctgcc aactcttcat atagtttcaa
    41341 tgcttgggta gttgctggca atacaagatc cattttttct gcttcttcta atgcaatctt
    41401 taaatctttg ataaaatgtt tgacaaaaaa accaggtgtg taatcttctt ttaaaatacg
    41461 aggagaataa ttgcttaaag accagttagc tgcacttcca cctgaaagcg tctcaatcac
    41521 tttctttaaa tcaagtccgt ttttttgtgc atagacaagc atttccgtca ttcctgtcat
    41581 cgtacctgca atcatgatct gattagccat ttttgtatgc tgacctttcc cagcagaacc
    41641 atgcaatgta aatgtcgtac caaattcttt gaataaaggc agtacttgat cataaacggc
    41701 ttcttctcca ccgaccatga tcgtcagtgt accattcttt gctcctaagt caccaccgga
    41761 taccggtgca tctaacgcat ctgcgccttt ttcttttgct gtttttgcaa ttttttctgc
    41821 caggcttggt gtacttgtag tcaaatcaac taaaatatgt cctgagatat ctgcagaaaa
    41881 aatccccgac tgtccatagt agatttcttc tacatctttg gggtaaccta ccattgtaaa
    41941 gagaatatta ctttgttctg ctaccgcttt tggtgtatct gcccagatag ctccttctgt
    42001 tactaaagga tcagcttttg cttttgtccg attatagaca gctacttcgt gtcctgcttc
    42061 tagtagatgg cgtgcgacag cacttcccat gacgcctgtt ccgataaaac caagtttcat
    42121 tttttcgacc tcctaaaaat caaaaatcct tgcttctatg ctagtatacg ctagaaacaa
    42181 ggattttttc ataaaaaatg tttgaatttt atcttttaaa tgaatttaat tttattttga
    42241 ttcgttcaat cgagtcttct tcttcttttc ttcgcatctc ttcttcatga taaacaacca
    42301 tgtcttgata aaattcgatc atagcttcgc cgaaatgtgt agatgaaata tcataaagtt
    42361 tagcttctaa aacttttgga tctttaggaa cttcactgga aatataatca ataagtgctg
    42421 gtgcaaagtc ttcgtcggtt tcaaaagttt tccctaatga aggatgatcg aacaatcggt
    42481 tcaaataagc atttccttcc acgacacaag gtgttccggc tgccatcgct tctgtataag
    42541 taagcccttg tgtttctgaa gtagaagcac tgacaaaata atctgccgct ttataataaa
    42601 gtgctacatc attgttgtcc acttctcctg tgaactgcac aaattcttct aactgcagtt
    42661 ctgagatcaa ttcctctaac tcttctacat aaggtccttt tcctacgata actaatctgg
    42721 cgttaggata agcggagatg acctgaggaa acccattaat caaggcttgg atatttttct
    42781 cataagaaat cctgcttaaa gaaagaatca tcaaatggtt ttcctgaaga cctagtgact
    42841 cccttaattt gctgatatcc tgctgagtga tatcagaacg tttgaatttt tcaatgtcga
    42901 taccagtagg aatcacgcga agcggtgcta ttacaccata gctgcgtaat gtatcaataa
    42961 cacgttcact tggacaaact acacctgtcg tatgatttgc aaataatcta gacaagtatt
    43021 ttacatggga ttgcctgatc acttttcctt taccgatata atgaaggtag tcttcataca
    43081 tcgtatggta agtatggatc agaggtattt tcaacttctt agctaccatc ttcccaagta
    43141 tccctgctcc gaattctgta tgggtatgaa taagatctag ttctagttct ttggcaacca
    43201 aataagcata ccacatgcct ctaacaacaa ctcttcgatc cttgaaagaa ataaatggta
    43261 cacttggcat tcgaatcaca tctttttcca acttatccgc attaggatcg gtcgttgtaa
    43321 aaatatagac ttcatgccca tgtctttcta attcttgttt taatgttttg atcgatgtag
    43381 caactccgct gacttgcgga aagtaggtat cggtaaaaaa gccgattttc atgtttttcg
    43441 cctccaaact agtccttgac ctgatttact ttttttaatt tgctagagac tttttcattc
    43501 agtacacttt cgtatacatt tttaagttct tcaccgattt tattgatact tcgctctttt
    43561 gctgtttgat aaccggcttg tgtcgtactc ggtagttctt gattggtaat ctgttggatc
    43621 agtcggataa attcttcgtt tgtcttcccc atatagcagt tcttgctatc ttctaaccag
    43681 ccattataca ctggaatatc tcgaacaagt acgttttgtt tgcttgctaa agcttctaaa
    43741 acaacgatcc cttctgtctc ttcataagaa gggaaaaaga atagatctgc acctgaatac
    43801 gcaccttcta tgatctctcc acgaatgtaa ccaggaaaca ggacattttc aggatgatct
    43861 tcttttacaa ttttccggat gttccgagga atcgagtaca tgggaacatg accaaaccaa
    43921 ataaatgtgt attcgggcat cttcttagca atttctacga aatcaatgat tcctttacgt
    43981 tcgaaaaaca aaccgacaca aatgattact ttttgatccg gagacagttt gaaatattct
    44041 ctgaactttt gttctttcat tggatcaggg tgatatttct ctaagtcgat cccattggaa
    44101 atagcttgaa tcggcacacg gataccatag ctttccaaca actgttttga ataaggtgtt
    44161 ggcgtgatca gatagtccgc tttttggtac aatcctacca gatatttttt tacgatagga
    44221 gaaagctggt tcgatccgat aaaggaattt cggaaatctt cctctgtaga atgcgcatga
    44281 tagacaactt tttttccttc tcttctggct ttattgacca tattatgact attgattccg
    44341 tatgtattga tgtgcaggat gtcataatct tctttttcat ctagtgtata agagataccg
    44401 acttccgtca gagcacgttt ttgatgatca agcgcacgcc cgattccaga ttttgcaagc
    44461 atcttttcac tttcaaaata taataatacc ttcaccttac gtcccccttc acttatatag
    44521 tataacatag cctacaaact gtcactcaaa cttaagccct atttttgtct attcttactg
    44581 acaaaaacgt tttcttaaaa aagaacaaaa aaactggcgt agctctttta caagccacac
    44641 cagcttttga tacgttgttt attttacata ttcatgaaca agttcaacga cttcttccat
    44701 catatcgcat tctttcaatg cacgatcagc aagttcagcc attttcgctg tgtccaagcg
    44761 tttcattaaa ctacgcgttt taagaataga tgtcgcactc attgagaact catctagacc
    44821 catacctact agcaatggaa cagctgtttg atctccagcc atttctccac acatacctgc
    44881 ccattttcct tcagcgtgtg ctgcatcaat tacatttttg atcaaacgta aaattgatgg
    44941 gttatatggt tggtacaagt aagaaacgcg ttcgttcata cggtctgctg ccattgtgta
    45001 ttgaatcaaa tcgttcgtac ctacagagaa gaaatctact tcttttgcaa acttgtctgc
    45061 taagactgct gctgctggaa tctcgatcat gatgccgact tggatcgtat cagatacttc
    45121 cttgccttca cttatcaatt tttgtttttc ttcttcaaag atcgcttttg ctgcgcggaa
    45181 ttctttgagt gtagctacca tagggaacat gatacgtaaa ttaccatgaa cagatgcacg
    45241 aagcaatgca cgcatttgtg tacggaacat ttcgtcgcct tgttcagata aactgatacg
    45301 caatgcacga tatcctaaga atggattcat ttcatgaggt aattgcagat atggtagttc
    45361 tttatctcca ccgatgtcca ttgtacgaac aactacaggt tttccttcca taccttctaa
    45421 tacagctttg taagcttcat attggtcatc ttctgttggg aagtctggag aatccatata
    45481 caggaattca gtacggtaca gaccaactgc ttctccacca ttattatgga caccaactag
    45541 atcttttggt gttccgatgt ttgcagctaa ttcaaaatgc ttgccgtcag ctgtgacagt
    45601 ttctgcattt tttaattttt cccattctgc tttttgtgct gcgtaatctg cacctgcttt
    45661 ttcaaattca gctttttgtt catctgtagg atcgatgatt acatcgcctt cgatcccgtt
    45721 gacagccaaa atatcgcctt ctttgacttt agcagtaatt tcttttgtcc caacgattgc
    45781 tggaatttct aaagaacgtg ccatgatagc agaatgtgaa gtacgtccac caatgtctgt
    45841 tacaaacgct tttacaaaat tgcgatctaa ttgtgctgta tcacttggag tcaagtcatg
    45901 tgcaacaacg accacttctt cgttgatcat tgatggattt ggtaaagtaa cgcctaataa
    45961 gtgcgctaaa atacgtttag caacgtcacg aatatctgca gcacgctctt gcatataagc
    46021 attatcttcc attgcttcga acataccgat atacatatcc gttacttctt ttagcgctga
    46081 ttcagcattt acgctgttgt ctttaatatt ttgcttgatt tgacctacca tttctggatc
    46141 tgaaagaacc atcaaatggg catcaaatac ttgcgcttct gcttcaccta agctttgcgc
    46201 tgctttttca cgaatttgct gcaattcttc agtagattta gctaatgcag catccaaacg
    46261 agcttcttca gccgcagtat cttctactgt tgccttactg aatgttaaat ccggttgaac
    46321 tagcaggtaa gcttttgcaa cggctacacc gtcactagcg gcaatccctt ttagcatttc
    46381 aaccattatt cagataagcc ttctttcttc attgtttcaa cgattgctgc cattgcatca
    46441 gcttcgtcag caccttctgc agtaatagta acatcagaac cttgacctac acctaaagac
    46501 ataacgccca tgattgattt caagtttact gatttacctt tatactctaa gtttacatca
    46561 gagttaaatt tgcttgctgt ttgtactaat agtgtagctg gacgagcgtg gatcccagtt
    46621 tctgctacta cgtgaaattc tttcttttcc atattaatcg gtctccttta agtgagtgtt
    46681 gtttttatgt gagggttttc ttttttagta attcagagaa tcctaacaaa tgccaccctt
    46741 tcatctgtaa agattaacat tttttttcgt tagatacaac agttttcatt caatttcaga
    46801 taaaagtatt caaattattc cggattcttt ttcatccttt tcttcacatt ttataacaaa
    46861 cgtgtttatt tcctttttct tgtcgctttc tcttctcctg acgtttatca ttctttcctt
    46921 tgaccctctt tgttttcata tgaaacgaat tacttgcttc cctttttatt tttagtataa
    46981 taagagtcaa aggtcaggaa tggtcaatag agatttcacc ttttctacct cataaatctc
    47041 ttaaaaaact aggggttatt cttttacctc atgaaaaacg agatgtaaaa tatggatgta
    47101 cccatttttg tgaaaggacg tgaatgattc atgctttgtc aaaactgcgg caagaatgag
    47161 gcaacgattc acttgtatgc cactgtcaat ggtcagcgga cacaactcga ttactgtcag
    47221 agctgttatc aaaaaatcaa aaatcaacaa aatggaggtc tgactaatat ggcccaaaat
    47281 gatccatttg gatttggcag tttggacgat cttttccgtt ccatgtctcg ccaaatgcaa
    47341 cagcaaggaa attatgagca aacaccacca acacaatttg gcggaaacaa caacttcaat
    47401 ggtggtcagc cacctcaagg caatacagaa ggtttattgg gagaatacgg aatcaatatc
    47461 acagaacaag cacgacaagg tgatatcgat cctgtgatcg gacgcgatga cgaaatcaaa
    47521 cgagtcattg aaattttaaa tcgccgaacc aagaacaatc ctgtcttgat tggagaacca
    47581 ggtgttggta aaacagcagt tgttgaaggt ttagcacaaa aaatcgtaga tggtgatgta
    47641 ccgcaaaaat taatggacaa agaagtcatt cgtttagatg tcgtatcttt agtccaaggt
    47701 actggtatac gaggacaatt tgaagaacgt atgcaaaaat tgattgaaga gatccgtcaa
    47761 gcagaaaatg tgatcctatt catagatgaa gttcacgaaa tcgtcggtgc tggttctgct
    47821 ggtgatggaa atatggatgc tggtaatatt ttaaaaccag ctttagctcg aggagaattg
    47881 caaatggttg gtgctactac cttaaatgag taccgcatca tcgaaaaaga cgctgcttta
    47941 gaacgtcgta tgcaacctgt acgggtagat gaaccaactg tcgaagaaac gatcagtatt
    48001 ttgaaaggtt tgcaaaaacg ttatgaagac tatcatcatg taaaatatac tgatgaggcc
    48061 atcgaagcag ccgcaacttt atccaatcgt tacgtccaag atcgcttctt gccggataaa
    48121 gccatcgatt tgctagatga aacaggttct aagaaaaact tgacgatcca aatcgttgat
    48181 cctaaaacaa tcgagaaaaa actgcaagaa gcagaagaac aaaaagtttt agcttctcga
    48241 gaagaagatt tcgaaaaagc agcttattat cgcgatcaga tcaataaact tcaaaaaatg
    48301 aaagaacgtc agctcactga agaggaaaca cctgtgatta ccgaaaaaga tatggaaaaa
    48361 atcgttgaac aacggacagg tattccagtg ggtgaattaa aagaaaaaga acagacacaa
    48421 ctgaaaaact tagcagatga cttgaaagct catgtcatcg gacaagataa cgctgtagat
    48481 cgagtagcga aagcgattcg ccgaaaccgt gttggattaa acaaacagaa tcgtccaatc
    48541 ggctccttct tatttgttgg accaactggt gtaggtaaaa cagagcttgc gaaacaactt
    48601 gcctacgaac tattcggttc acaagattca atgattcgtt tcgatatgtc tgaatatatg
    48661 gaaaaacata gtgtctctaa attgattggt tctcctccag gttatgtcgg atacgaagaa
    48721 gctggtcaat taacagaaaa agtacggaga aatccttaca gtcttgtctt gttagatgaa
    48781 gtagaaaaag ctcatccaga tgttttgcat atgttcttgc aaatcttaga tgatggtcga
    48841 ttgacagatg cacaaggaag aacggtcagc tttaaagata cgatcatcat tatgacaagt
    48901 aatgccggaa ctggtaaagt agaagcaaac gttggttttg gtgcggcacg cgaaggtgtt
    48961 actcgttctg tattgaacca attaaacaac tactttacac cagaatttct gaaccgtttt
    49021 gacgggatca tcgaattcag tgcattatca aaagaaaact tgatgacaat cgtcacacta
    49081 atgctagacg atgtcaacca aatgctggca gcacagcaac ttcacatcga agttcctacg
    49141 aatgtcaaag aaaaattagt tgacttaggc tatgatccat ctatgggtgc tcgtcctctt
    49201 cgacgcacga tccaagaaca aatcgaagat ggtatcgctg aattttatct tgatcaccct
    49261 tctatccatg agttgaaagc aaaactggat aaagatggaa aaatcatcgt tacttctaaa
    49321 ccagaacgtt tggctaaaga atcagccgaa gaaacggctg aataaatcca gttttatagc
    49381 gtgagacggt atttctttga gaaatgccgt ctcattcttt tttcagaaaa gtcaaaatac
    49441 tgttcatttt ataaaaaaga aattataata agagaaacaa gcaattaaaa atacataaaa
    49501 gaggtgagcg ccatgaaatt ggtaaatgta acaaacagcc attcccgtct tgtattaaac
    49561 cagcttgaaa acactgatgc ccatctagtc aaggtctaca cagccggaaa taccactatt
    49621 gtctacactg aagcccctga acataatgaa attctgctga tcaatgacaa acgtaaaatc
    49681 cagccgaaag aaatcgaaga tgctaaaaat tatttcttag ataaaatcaa agacgccgtt
    49741 taccacgagg atgaaatcaa agtaatcgaa ttggcaggcc ttgttgaaat ctcgattcca
    49801 aaacatgaat taggcgctac attagccgtg taaacaaatt ttgaacataa taattaaaga
    49861 gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat aaacggcgaa
    49921 agcagaagca actccttcgg aaataagctg aaattcacga aaattgcttt tcaaattttt
    49981 gtgaattcca gcttatttct tggagttaaa cgcttctgtc tcagcctctt tttctttcta
    50041 gctttttgat ttttctcttt tcttttgtac ttttctcttt tcattttcag ttctacgcgt
    50101 gtctttattt ttaacttttt cctctttatg gatgattgat cgtacttttt gtgcaatttg
    50161 ctcgtttttg tcccagtctt ttacatctaa taatcgacat aatcgtaaca tctcttcttt
    50221 tttctgtttt tttctttcac gtctttgcca ttctgtttcc atgtgtcaca ctctcctttc
    50281 tttaatcata tgtacgcaaa ataattttta tatttttttg attagac
//
LOCUS       DAXLPY010000013        49483 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.013, whole genome shotgun sequence.
ACCESSION   DAXLPY010000013 DAXLPY010000000
VERSION     DAXLPY010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.013"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(271..1998)
                     /locus_tag="ACF3UF_000848"
     CDS             complement(271..1998)
                     /locus_tag="ACF3UF_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFD3670998.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(1991..3184)
                     /locus_tag="ACF3UF_000849"
     CDS             complement(1991..3184)
                     /locus_tag="ACF3UF_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3670999.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3371..4015)
                     /locus_tag="ACF3UF_000850"
     CDS             complement(3371..4015)
                     /locus_tag="ACF3UF_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3671000.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4109..4243)
                     /locus_tag="ACF3UF_000851"
     CDS             complement(4109..4243)
                     /locus_tag="ACF3UF_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFD3671001.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4245..6377)
                     /gene="feoB"
                     /locus_tag="ACF3UF_000852"
     CDS             complement(4245..6377)
                     /gene="feoB"
                     /locus_tag="ACF3UF_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFD3671002.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6374..6847)
                     /locus_tag="ACF3UF_000853"
     CDS             complement(6374..6847)
                     /locus_tag="ACF3UF_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFD3671003.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7248..7472
                     /gene="nrdH"
                     /locus_tag="ACF3UF_000854"
     CDS             7248..7472
                     /gene="nrdH"
                     /locus_tag="ACF3UF_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFD3671004.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            7631..9790
                     /gene="nrdE"
                     /locus_tag="ACF3UF_000855"
     CDS             7631..9790
                     /gene="nrdE"
                     /locus_tag="ACF3UF_000855"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFD3671005.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            9840..10805
                     /gene="nrdF"
                     /locus_tag="ACF3UF_000856"
     CDS             9840..10805
                     /gene="nrdF"
                     /locus_tag="ACF3UF_000856"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFD3671006.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(10894..12033)
                     /locus_tag="ACF3UF_000857"
     CDS             complement(10894..12033)
                     /locus_tag="ACF3UF_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3671007.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12342..13055)
                     /locus_tag="ACF3UF_000858"
     CDS             complement(12342..13055)
                     /locus_tag="ACF3UF_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFD3671008.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13309..14010)
                     /gene="nagB"
                     /locus_tag="ACF3UF_000859"
     CDS             complement(13309..14010)
                     /gene="nagB"
                     /locus_tag="ACF3UF_000859"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFD3671009.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14244..15776
                     /locus_tag="ACF3UF_000860"
     CDS             14244..15776
                     /locus_tag="ACF3UF_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3671010.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(15967..17169)
                     /locus_tag="ACF3UF_000861"
     CDS             complement(15967..17169)
                     /locus_tag="ACF3UF_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3671011.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(17251..17940)
                     /locus_tag="ACF3UF_000862"
     CDS             complement(17251..17940)
                     /locus_tag="ACF3UF_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFD3671012.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18046..18414)
                     /gene="rplL"
                     /locus_tag="ACF3UF_000863"
     CDS             complement(18046..18414)
                     /gene="rplL"
                     /locus_tag="ACF3UF_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFD3671013.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(18467..18970)
                     /gene="rplJ"
                     /locus_tag="ACF3UF_000864"
     CDS             complement(18467..18970)
                     /gene="rplJ"
                     /locus_tag="ACF3UF_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFD3671014.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(19174..19301)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(19380..20069)
                     /gene="rplA"
                     /locus_tag="ACF3UF_000865"
     CDS             complement(19380..20069)
                     /gene="rplA"
                     /locus_tag="ACF3UF_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFD3671015.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20173..20595)
                     /gene="rplK"
                     /locus_tag="ACF3UF_000866"
     CDS             complement(20173..20595)
                     /gene="rplK"
                     /locus_tag="ACF3UF_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFD3671016.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            20938..21606
                     /gene="sdaAB"
                     /locus_tag="ACF3UF_000867"
     CDS             20938..21606
                     /gene="sdaAB"
                     /locus_tag="ACF3UF_000867"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFD3671017.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            21619..22491
                     /gene="sdaAA"
                     /locus_tag="ACF3UF_000868"
     CDS             21619..22491
                     /gene="sdaAA"
                     /locus_tag="ACF3UF_000868"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFD3671018.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(22582..23682)
                     /locus_tag="ACF3UF_000869"
                     /pseudo
     CDS             complement(22582..23682)
                     /locus_tag="ACF3UF_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(23774..24661)
                     /locus_tag="ACF3UF_000870"
     CDS             complement(23774..24661)
                     /locus_tag="ACF3UF_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3671019.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(24738..25283)
                     /gene="nusG"
                     /locus_tag="ACF3UF_000871"
     CDS             complement(24738..25283)
                     /gene="nusG"
                     /locus_tag="ACF3UF_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFD3671020.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(25384..25554)
                     /gene="secE"
                     /locus_tag="ACF3UF_000872"
     CDS             complement(25384..25554)
                     /gene="secE"
                     /locus_tag="ACF3UF_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFD3671021.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(25578..25730)
                     /gene="rpmG"
                     /locus_tag="ACF3UF_000873"
     CDS             complement(25578..25730)
                     /gene="rpmG"
                     /locus_tag="ACF3UF_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFD3671022.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            25892..26536
                     /gene="cbpA"
                     /locus_tag="ACF3UF_000874"
     CDS             25892..26536
                     /gene="cbpA"
                     /locus_tag="ACF3UF_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFD3671023.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(26592..27095)
                     /locus_tag="ACF3UF_000875"
     CDS             complement(26592..27095)
                     /locus_tag="ACF3UF_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFD3671024.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27108..27154)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            27692..28657
                     /locus_tag="ACF3UF_000876"
     CDS             27692..28657
                     /locus_tag="ACF3UF_000876"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3671025.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(28756..29928)
                     /locus_tag="ACF3UF_000877"
     CDS             complement(28756..29928)
                     /locus_tag="ACF3UF_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671026.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(29915..31060)
                     /locus_tag="ACF3UF_000878"
     CDS             complement(29915..31060)
                     /locus_tag="ACF3UF_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671027.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(31074..31998)
                     /locus_tag="ACF3UF_000879"
                     /pseudo
     CDS             complement(31074..31998)
                     /locus_tag="ACF3UF_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            32115..33194
                     /locus_tag="ACF3UF_000880"
     CDS             32115..33194
                     /locus_tag="ACF3UF_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFD3671028.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            33191..33819
                     /locus_tag="ACF3UF_000881"
                     /pseudo
     CDS             33191..33819
                     /locus_tag="ACF3UF_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(33929..34156)
                     /locus_tag="ACF3UF_000882"
     CDS             complement(33929..34156)
                     /locus_tag="ACF3UF_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3671029.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(34259..36847)
                     /locus_tag="ACF3UF_000883"
     CDS             complement(34259..36847)
                     /locus_tag="ACF3UF_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFD3671030.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(36867..37526)
                     /locus_tag="ACF3UF_000884"
     CDS             complement(36867..37526)
                     /locus_tag="ACF3UF_000884"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3671031.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(37575..38078)
                     /gene="trmL"
                     /locus_tag="ACF3UF_000885"
     CDS             complement(37575..38078)
                     /gene="trmL"
                     /locus_tag="ACF3UF_000885"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFD3671032.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(38299..39165)
                     /locus_tag="ACF3UF_000886"
     CDS             complement(38299..39165)
                     /locus_tag="ACF3UF_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFD3671033.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            39274..39915
                     /locus_tag="ACF3UF_000887"
     CDS             39274..39915
                     /locus_tag="ACF3UF_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFD3671034.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(39977..41338)
                     /gene="mgtE"
                     /locus_tag="ACF3UF_000888"
     CDS             complement(39977..41338)
                     /gene="mgtE"
                     /locus_tag="ACF3UF_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFD3671035.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(41356..42255)
                     /locus_tag="ACF3UF_000889"
     CDS             complement(41356..42255)
                     /locus_tag="ACF3UF_000889"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD3671036.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(42257..43054)
                     /locus_tag="ACF3UF_000890"
     CDS             complement(42257..43054)
                     /locus_tag="ACF3UF_000890"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFD3671037.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(43032..43736)
                     /locus_tag="ACF3UF_000891"
     CDS             complement(43032..43736)
                     /locus_tag="ACF3UF_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFD3671038.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            43867..44442
                     /locus_tag="ACF3UF_000892"
     CDS             43867..44442
                     /locus_tag="ACF3UF_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFD3671039.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            44560..45237
                     /locus_tag="ACF3UF_000893"
     CDS             44560..45237
                     /locus_tag="ACF3UF_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFD3671040.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(45316..47124)
                     /gene="pepF"
                     /locus_tag="ACF3UF_000894"
     CDS             complement(45316..47124)
                     /gene="pepF"
                     /locus_tag="ACF3UF_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFD3671041.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(47300..48298)
                     /locus_tag="ACF3UF_000895"
     CDS             complement(47300..48298)
                     /locus_tag="ACF3UF_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFD3671042.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(48524..49177)
                     /locus_tag="ACF3UF_000896"
     CDS             complement(48524..49177)
                     /locus_tag="ACF3UF_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFD3671043.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        14794 a        10394 c         8723 g        15572 t
ORIGIN      
        1 gtatataaac tatgtatatt ctttaatatt ttttgagaat gcacttcgta cataataaac
       61 tttaatcaca ttagtctttc atacctacga tcgatctctt tgactcgcac ccataaattc
      121 ataatagttt gtcggcgtct ttggacgttt cgaagatgag ctacgcattc tcttttttta
      181 tagacaaaaa agatagagac gaacatggag cttccaaatt tggatatttg atccaatttt
      241 ggaagctcca tttatttcgt gtctgtcttt ttattttttc cagctttcga ctaattcttg
      301 gttctctttg atccagtctt ttgctgcttg ctgtggatct tttccattgt tgatttccaa
      361 cataactttt tccatatctt tttctgacca atggaaattg tctaatactt tgtaagcttc
      421 tggctggtct tctttcaatc cttttcgaac catcgtatgg atctgctctt cgcttcccat
      481 tccgttttca ggatcttcta agtatttcag atcatatttg gcaaacatcc aatgaggtgt
      541 ccatcctgta actacaattg gttcgtgttt tttgatcgct tgacctagtg caacggtcat
      601 tgctcctgaa gaagatgtct ctactttcca gtctttcaag ttgtcatatt tttggatcgt
      661 gttttcagca gccgtaacta caccagctcc tggctcgatt cctatgattt tcttacctgc
      721 ctgatcggtt aactcatcga tcgaatttac atccatgtag gctggcactg ctaaaccaac
      781 ttttgctcct gtcaaattgg cacctaggtc ttcgacttga tctttatatt gtgcatattg
      841 tgaaccatga gttttaggta gccaagctga aaccatggca tctgactcgc catttgaaac
      901 agatttccac atgattgaat tatctaatgg cgtcatcgtt acatcatagc ccatttgttt
      961 caatacttca ccgactacat ttgttgaagc aacttctgta tcccattcaa cataagataa
     1021 gttgatacgt tttgtttctt tggcagatga aaaactccct ataccaatcg cacctaagat
     1081 cactactact acagcaccaa tgatcagtcc ttgacgtttt ttacttttct gtgttgttgc
     1141 tcctgcagct tttttattgt ttggctggtt caaatgctgt gtaaaacggt caatgatgat
     1201 tgctaagata actaatgcaa ccccgttgac aaatccattc ccgacttgtg ctctttgcaa
     1261 tgctgataat acgccgcgtc ctaagccggg tgcaccgatc atagaggcaa taacgaccat
     1321 tgaaagtgac agcattgttg tttgattgat ccctgccatg atcgtacttt tagctaaagg
     1381 caattctagt ttgaatagtt tttgacgact tgtgctcccg aatgaatcag aagcttctac
     1441 taattcttta ggaacttgtc gaatccctaa attcgtaaaa cgaacggttg gtggcagagc
     1501 aaagatgact gaggcaaata cccctggaac catcccgata ccgaaaaatg caactgctgg
     1561 aatcaaataa acgaatcctg gcattgtctg cataaagtca aggatcggtt tgataatact
     1621 ttgggcttta ctgctttttg ccatcaagat ccctaatggt accccaatga tgatcgagat
     1681 cacactagat aaaagaacaa gtgtgacagt attcatcaaa tcattccata gaccttggtt
     1741 ataaataaac catagaccga ttaatgtgaa caacgtaagt cctggacgtt tcttagaaat
     1801 aaagaaagct gctaccgtca ataacaagat aaacaaagga gctggaatca ctaacagtaa
     1861 atttgtaatc cccgacatca ctgcctgtcc aatcgtttgt aaaaatgaaa ataggccaga
     1921 aaaagttgtc gtaaaccatt ctgtgatatt ttctacccag tttgccactg gtaattgata
     1981 gttcaataga ttattcatgt tcactcacct cgcttgtttc tgctaatgct tcaatcacac
     2041 tacctcggat gacgacacct tttaattttc catcctctac aactgcaagt ggagtcggtg
     2101 agtcataaat aatattgaaa atatcactta ccaccatgtc tttcccaatc accgtcacat
     2161 tttcatctag gaagtcgatc aatggacgtt tttgcttcct agcttctaac gcttgatctg
     2221 cagtgatgat ccctttcagg tgtctctttc tgtcaacagc catcagcatg ctgacttctt
     2281 cattacgcat ccttgtcaat gcaacgtttg gtccatcaga ttcgatattc gtcgtcaatg
     2341 caggtaccat gatgttttga gccgtaagca ctttggaacg atcgacttct tccacaaatt
     2401 cacgtacata atcatttgct ggattggtca atatttcttc acctgttccg atctgcatga
     2461 tttcgccgtc tttcatcaag gcgattctgt ccccaatccg taaagcttca ttcaaatcat
     2521 gggtaatgaa aataatcgtt ttttgaacat tggcttgcag gtccagtaat tcgtcttgca
     2581 tttctcgccg gatcagcgga tcaagagccg agaacgcttc gtccatcagc aagatctcag
     2641 gatcatttgc taaagctctg gctaggccaa cccgttgttg catcccacca gataactgac
     2701 taggatattg gtctttaaat gaaagcaaac tagaattttc taatgctttt tctgcttttt
     2761 cttgtcgttc ttctttaggt acaccacgga cttctaaccc gtattctgta ttttccaaga
     2821 tcgttcgatg tggaaacaga ccgaagtttt ggaaaaccat attgatttta tgacgacgga
     2881 cttctcgcaa ttcttctttg cttaacttcg atacatcttc tccatcaata tagatactgc
     2941 ccgaagttgg ctcaatcaga cgattcaata gacggatcaa tgtggatttc ccactcccgg
     3001 aaagccccat gatcacgaag atttctcctt cttttacgtc aaaattcacg tcatacacac
     3061 caaccgttgc accggttttc tttaaaatct ccgttttcgg ctggtgatca ttcatcatat
     3121 ctaaagcggc ttgtgtcttt ttaccaaata tctttgttaa atgttttact tctactttta
     3181 ccaaacaaat tctccttttt tatgtaaatt catttttctt tctgaaaaaa gtgaccacac
     3241 tatgttaaca tcatgtagtc actttgtcaa aaatgaaaga aatttgcttg tccaaactga
     3301 aaaaaacttg gctaaatctt tgtaaataaa aggtttagcc aagttaatat ttttttaata
     3361 tttcacacaa tcattctgca agctgatgct ccgggtaaaa aaagtttgtc atacgctgta
     3421 gtgtatattc atttccaata aaatgaacga tgtcccctgc cgtaaattta gcataggggc
     3481 caggtgaaac aagcagttct tcattatgag aaattgcgat aactgtggcg ccagtcgcct
     3541 gccagatatt caactcgcta attgaacggt ccagatgcat tgctttttct gataaagata
     3601 attcaaacgg aagtaaagga ttcatcttat gtattcgctt cgtttgattg accagctgat
     3661 ccaataattg agaaaaatga ttcagctcat cttgttgctt ctccacactt gccatgattt
     3721 ctgcttttgt atcttggatg gattgtacat cttgatattg caataggaaa tcttttgctt
     3781 tttccttcga agcaacaaat gccccacttc catgccgtac ttccatgatt ccaagatcta
     3841 ccagcacatt gatagccttg cgggtagtct caggagaagc attgtacgta ctggcaagtg
     3901 ttgagcgggc atggatcttc tcacccactt tatatcggtt ttcaacgata cgttcggcta
     3961 aatcaacagc aatctgctgg tagcgcgggc ggacgatttt tttctttcca gacattttct
     4021 ttcctctttc tttttttact ttccctcatc ttactatgct ctagcaaaat aagcaaaaaa
     4081 ggggagaata gcctcttgca acgactgatc atcgcttgat ctgttccttt tttactgggc
     4141 aagctgtttg acagtcatca caattcttac cggattttaa acgagtatag acaattgcgc
     4201 ctgcacttcc aaagattaac acacttaata agaatgtcgc catcctattc ctctccttct
     4261 aatgacaata tagtataaaa ctggttcttg gattttggct gacggaacaa aacataaacg
     4321 agtcctatca tcagtaaaat agcaagatac gtccctaacg ctacctgtcc accctccaat
     4381 aagtgtccca actgataaat cacaaaacta actaaataag ctaaaccgca ttgatagcct
     4441 atggcgatcc aagtccattt cttggcattc atttcccgat ggatagcccc aattgccgca
     4501 aaacaaggcg cacaaagtaa attgaaggct aacaatgaat aagctgctgc gggagtatat
     4561 gtgtgttgta gcacttgcca gatttctctg ccattttcgg atacttccgc atgaccaaac
     4621 aaaataccaa atgtgccaat aatattttct ttagcgacca atcctgtaat cgctgcgact
     4681 gttccttgcc agtttcccca accaagcggc tgaaaaacaa ctgccaggat tcgcccgaaa
     4741 aaggctaaga tactttggtc ttcagaaaca ggttgagcat aaaaattata agaagagctg
     4801 aaccagatca cgatactaga aacaaagata atcgttcctg cttttttaac aaaagacttg
     4861 ctgcggtcat aggtttgtct taggaccgct gaccattgag gaaaatgata tgcgggcaat
     4921 tccatgataa aaggagctgt atctccagca aacaaacgtg tttttttcaa gctgattcca
     4981 gagaaaataa ttgcagtcat accaagaaaa taggcagaag gagctaccca agattgatga
     5041 ggaaaaaagg cccctgctac taaggcaata atcggcaact ttgcagaaca aggcatgaag
     5101 gttgtgacca tgatcgtcaa acgacgatct tgctcgtttt caatcgtgcg actggccatg
     5161 acgcctggca ctccacatcc tgtagcaatc agcataggaa tgaaggattt tcctgaaaga
     5221 ccgaatttcc tgaaaagtcg atccatgaca aaagcgatcc tcgccatata tccgcagtct
     5281 tccagaaagc tcaagcataa aaacaatata atcaattgcg gtagaaatcc taacactgct
     5341 cccacgcctg cgatgatgcc gttcaagatc agctcctgca tccatcccgc tacttgccat
     5401 tcagctaaca atctgccaac atgttctggt aaccatgtac caaacaatgt gtcattgatc
     5461 caatctgtcc ccattgttcc tactgtttga atagccagat aatagatcag ccacatcaca
     5521 aatgcgaaga tcggcaaggc taaccaacga ttcgttgcaa tctgatcgat tttgtcactc
     5581 atcgataatt ggaaagaatc atttgacaca acacagagtg tacatagttg ggtaataaat
     5641 tcataacgtt cattgaccag aatcgtctca ctatcgtcgt ccaatagttt ctctgttaac
     5701 tggatcagtt gctcgatctc tttttgctga gaaactgcta tctcgtaatc ctctcttacc
     5761 ttctgatctc gttcaaaata tttcattgca taccagcgtt tcttgccgct ttgttctcct
     5821 agtacatctt caatttcatg taaagctgct tctaaacgtg gatcatatgt acagggaaca
     5881 ggaatagaag gccgcttttt tgcagactcc tgaatctttt cgattagttt ttcgattcct
     5941 tgctttttca atacgctgat tggtaaaact ggtacaccaa gaccatagga aagcttttct
     6001 agattgattt tttttccttc ttttttgatg acatccatca tattcagacc aatgatcata
     6061 ggaatgtcta aatccaataa ctgcgtagtt aaataaagat ttcgttctaa attggtagca
     6121 tcaataatgt tgatgatcag ttcaggctgt tcctgaacca aataatctct tgcaatcact
     6181 tcttctggtg tataaggaga caaagaatag atgccgggta ggtcctgaat atgaatgttc
     6241 ggattttttt tcaacgatcc ttcttttttt tctactgtta cgcccggcca attccctaca
     6301 tattgattcg aaccagtcaa gagattgaac aagctagttt tcccgctgtt tggatttccg
     6361 actaacgcga tattcattct ttttcctccc tttgtatcaa gattagttcg gcctctgact
     6421 ttcgtaacgt cagttcatac cctcgcactg tcagttcgat tggatctccc agaggggcta
     6481 gttttcggat aactattttt acatttcgcg tcaatcccat atccattaac cgtcgcttca
     6541 ctgcgccttg tccgtggatt gctacgacga tcccagtctc tcctgctttt aattgatcaa
     6601 gagaagtcca gctttcagag gaagcagtct ttttattgac aaagatttga cctagtattt
     6661 cccgacttac tgccactcga tgacttttta ccagtaaaat ggcattgttg cctgataaat
     6721 tgacgacgac gattttactt ccggcaacga tcccgatatt ttgcaaatgg cgttttgttt
     6781 tttcttctgt ttcgattcgt tcgacttgat aaacgaaatt ctgctttgcc tgcgctaagg
     6841 tctgcatatt gattcctctc ttgtgaaata aatcatgtat taaaatcatt cattatatgt
     6901 tctaattttc ttacgtgtta cgcaaataaa tgagaatcat tctcacatag aatactctcg
     6961 gtaattgaga atgtcaatta tacttgtgat attatgagcg aatctttagt attgatagat
     7021 aaaaatgaga aaaaaatatt tcttcatagt tttccacaat tttttctcta ttaaatttgc
     7081 tattttccca cacgatactt gttttcagct cttttttcaa aaacacaaaa cttagtattc
     7141 cacagtttcc acaacacaat atgtagtgtt tgttgtttga cttttttact aagagtttta
     7201 tactatctat tatagataat aagaatgtgt tagaggaggc actcaccatg aacgtaaaaa
     7261 tcttttctaa aaataattgt atgcaatgta agatggtcaa acggttttta acagaaaatc
     7321 aaattgcttt tgaagaagtc aatatcgatg aacagcctga agcagtagac tggttgaaag
     7381 cacaaggatt ccaaagtgtt cctgtcatta cttctgatgc agaaacagtt atcggattcc
     7441 gtcctgatca gttgcgtaaa cttgccagct aacatgacta aaagaatcaa aacgtgatac
     7501 atggatttga agggcttgag acagcaccag tttttgtcgc aaacttccaa atcctttttt
     7561 aaagcttaaa aacaatgcaa tgatttgcaa tcaagcatca tcaaatacga aatgaaggtt
     7621 gggcgtacgt atgagtctta aaaatttaca agatgtcagt tatttcaagc tgaataatga
     7681 aatcaatcgg ccagtcaatg gtcaaatccc tttgaataag gataaagaag ctttagttgc
     7741 cttttttgag gaaaatgtca aaccaaatac gatgactttt ctatctatta tggaaaaaat
     7801 caattacttg atcgatcaag aatatataga agcagaattc attcaattgt attcaccatc
     7861 atttattgaa aagctatatc aatttttgga cgagcaacat ttttctttca aatcttttat
     7921 ggctgcttac aaattttatt ctcaatatgc gttgaaaacc aacgacggtt ccgcttatct
     7981 ggaaacttat gaagatcgag tagccttcaa tgcgctttac tttgcgaacg gggatgaaga
     8041 attagcactt gctcttgcag acgaaatgat ccatcaacga tatcagccag ctacaccttc
     8101 tttcttgaat gctggacgta aacgtcgggg cgaattggtg tcttgtttct tgactcaagt
     8161 cactgacgat atgaactcta tcgggcgctc aatcaactct gctttgcaat tgtcccgtat
     8221 tggtggcggc gtagggatta ctttatcaaa tcttcgtgaa gccggcgctc ctatcaaagg
     8281 atatgagggt gctgcaagtg gtgtcgttcc agtcatgaaa ttattcgaag atagtttcag
     8341 ctattctaat caattaggtc agcgtcaagg agctggcgtg gtttatttga acgttttcca
     8401 tccagacatt attgctttcc tttcagcaaa aaaagaaaat gcagatgaaa agattcgcgt
     8461 aaaaactctt tctcttggcg tgatcgtacc tgataaattt tatgaattga cacgtaaaaa
     8521 cgaagatatg tatttattta gtccatatag tgtcgaaaaa gaatatggtg tcccattctc
     8581 ttatgtaaat attacagctg agtatgatca tctagttgca aatccaaaca ttcgcaaaca
     8641 aaaaatcaaa gcgcgtgatc ttgaaaatga aatctcaaaa ttacaacaag aatctggcta
     8701 tccttacgta atcaatattg atacagcgaa ccgcgagaat ccaatcgatg gcaagatcat
     8761 catgagtaat ttatgttcag agattttaca agttcaaacg ccttctgtga ttaacggcaa
     8821 acaggaatat gaagtattag gaacggatat ctcatgtaac ttaggctcga caaatatcgt
     8881 gaatttgatg caaagcccta actttggtca atctgtgcgt acgatgactc gtgcattgac
     8941 atttattaca gatgcatctg atatcgatgt cgtaccaccg atccaaaacg gaaataagct
     9001 gaatcatacg attggattag gtgccatggg cttacacact tatcttgcaa aagaacaaat
     9061 ggaatatggc tcagaggatt cattagactt tacaaatatt tacttcatgc tgttgaatta
     9121 ttggacactt gttgaaagca acaatatcgc tcgtgaaaga aaacaagttt tccataattt
     9181 tgaaaaatca gcttatgctg acggcactta tttcgaaaaa tacgtaactg gagaattcca
     9241 gccaaaatca gaaaaagtca aagcattgtt tgaaggcatt tttatcccaa ctgctgaaga
     9301 ttggaatgct ttgaaacaag cagtaatgaa agatggactg tatcatcaaa atcgcttggc
     9361 agtagcacca aatggctcaa tttcatatat caacgatacg agtgcaagta ttcatcctat
     9421 cactcgcatg atcgaagaac gccaagagaa gaaaatcggt aaaatttatt acccagcgcc
     9481 ttatctatcc aatgagacga ttccgtatta cacttctgct tatgatatgg acatgcgtaa
     9541 agtaatcgat gtttatgcaa tggcacaaca acacgtcgat caaggcatga gtttgacttt
     9601 attcatgcgt tctgaaatcc cagaaggcat ttatgaatgg aagacaacaa cgaagcaaac
     9661 gacacgtgat ttgaatattt taagacatta cgctttccac aaaggaatca aatccattta
     9721 ttacgtacgt acctttactg atgatgcaga agaaatcgga agcaatcaat gtgaaagctg
     9781 cgtgatctaa tatcatagat agattcgctt attcatattt taattaaagg agcattctca
     9841 tgtcagaaac atattatgaa gcaataaact ggaatgaaat tgaagatatc attgataaat
     9901 ccacttggga gaagctgaca gagcaatttt ggctagatac acgtatccca ctttcaaatg
     9961 acctagatga ttggcgtaca ttgtctcaat tggaaaaaga tacagtagga catgtatttg
    10021 gcggtttgac actgctagat actgtccaat ctgaaagtgg catggatcag ttgcgtaaag
    10081 atgtccgcac tccccatgaa gaagccgttt tgaacaatat tcaattcatg gaatccgttc
    10141 atgccaaaag ttattcttct atttttagta cactgaatac gaaaaaagaa atcgaagaaa
    10201 tttttgactg gacaaatacg aatccttatc tgcaaaaaaa agctgagcgt atcaatgaaa
    10261 tctacaaaca cggtacaccg ctagaaaaga aaattgccag cgtcttttta gaaacattct
    10321 tgttctattc aggtttttat actcctcttt attatttagg aaacaacaaa ttggctaacg
    10381 tagcagagat catcaaacta atcatccgag atgaatctgt acatggaacc tacatcggtt
    10441 acaaattcca attaggattc aacgagttac ctgaagcaga acaagaaacg ttaaaagact
    10501 ggatgtacaa tcttctttat gagctttacg aaaacgaaga acgttataca gaagaattat
    10561 acgatccaat cggctggaca gaagaagtca agacattcct acgctataat gccaacaaag
    10621 cattgatgaa cctagggatg gatccactct ttccagatac tgccaatgat gtcaacccaa
    10681 tcgtaatgaa cgggatttca acaggcacaa gcaaccatga cttcttctca caagtcggaa
    10741 acggctattt gttaggtcat gtagaagcga tgaaagacga cgattatttg attggattgg
    10801 aataaggatt tattttaatt caaaaatttt tcgaaaaata aaaagagttt agcgtacaga
    10861 tattttaaat gtacactgaa ctctttttta tgcttattca cttgtttctt ccagcacttt
    10921 tggactgtct aacttttccg aaacatgttc cattcttctc aataaataga ttttccggat
    10981 atttaatatt atcgtcttaa tcactgcata gacaggtatg caaatcagca tgcctaatat
    11041 tcctgcgaca cttcctgctc caatcaatac caagatgatc gtcaaaggat ggatattcat
    11101 tgatttccca aataacaacg gcttgatcaa atttccatct aattgttgga tcactaaaat
    11161 cgacaacgcc atatacaaag cttgaaatgg agagataaac aaaccgacaa tgattgctgg
    11221 taccgctcca ataaaagggc cgacatacgg gataatattc gtgattccgc aaatgaccgc
    11281 aagcaacaag ctataaggct gatcgaatat tctcattgcc aaaaagctca ttacaccaat
    11341 aatcaaagca tctaagatcg tactgctgat ataggcagat aatgtttcgt ttaattcttt
    11401 taccgtttgg cgtaactctt tacgaatcgc tttcggaaag aagtgagaca acgcatcaat
    11461 aaatttgtgc ccatccttga acataaatag caaaataaat ggaacggtaa ataacaaaat
    11521 aaaaaattgc atcataaatg aaatgatttt tgagacactt gcagataaac tgactaatat
    11581 gatattgaac aaattactaa gagataaatt tgctgatgct aattgttctt ccaaattgaa
    11641 atttttaaac tcttcccgct gcgccaattc atttaaccat ttgcttgttt catctgcata
    11701 cattggcaag ctctgggtca attgaattgt ctgttccatt aactgaggca ctacattcat
    11761 gacagttaaa acaactaaaa tgattacgac caaaaacgtc aataaaaaac cgaacactct
    11821 cgggatccga tgcttttcga gaaaaacaac gattggatcg aacatataat agataaaacc
    11881 agcaacaagc aatggtaaaa aaactgccga aagcattttc aatattggac taaaaatatt
    11941 cggcatttgt aaaataaagt acacgccgat gatcgtgagt actagctcca ctgtccagaa
    12001 aaataatttt gattgtttaa aacgtgattg catacatctc ctccaaggtc ctttgatact
    12061 tctattctat catttaacaa agagttacgc gctgagattt tcatttgctt aaaaaaaaca
    12121 aaaaaaataa acatatttta atgagtagac gagtacttaa acaaaaacac ggtttggagt
    12181 agtgacaaaa attatactgc agtccctttt tccaaataaa cggtgttcaa aagcttgcat
    12241 cttcgtaata agcccagcca aacgaaaaat ataaggaact atttttattt ggctgggctt
    12301 attacttgat gtaggacatc tattttacaa cctcagatca tttattgcgc aatactgact
    12361 aaatgcaact ttgtgatatt tttgtgtacg gacaactcct cgatcacatc ggcataagtg
    12421 agcccttttg gaagatcaat cgtatagata tttttgtaca ctcggtagtc atcaacgaat
    12481 tttacgtcaa aattcacatc ttcgattacg atatttttct cttcaaaata atcggtaaga
    12541 aaatctttgg tttcttttct atggataaat tggatttcta actttttagt cgtaggtaca
    12601 tggatcacgc gtttcactac tgtgagtgca atagcaatcc cgataaaact gatgatcgca
    12661 atggaatagt aacccatgcc gatggcgatc cctaatccag caattgccca taaagaagcg
    12721 gcagtcgtaa gtcccgtcac cgattgtttc gtgacgatga tcgttcccgc gcctaagaaa
    12781 ccgacaccac tcaccacttg agcaatcagc cttgcttcat ctgaacgaat cgttccagca
    12841 agctgtggat actctaaagc atctcttaat gcaccactag cgatctcaac ttggatcaat
    12901 gcaatgatac atgctcccat acaaactaaa atatgcgtac gcatacctgc tggacgattt
    12961 ttatattgtc gttcaaaacc gattgctccg ccaaatagca tagcgatccc taaacgtaaa
    13021 ataatctctg gaattgtcaa taccatatca ttcatctaaa caccctccag tccaatatat
    13081 catgtctgaa aggagcagac aaaaaaagtg caatttttac ctcttacgaa aaaaggactg
    13141 tgacaaaatt tttgtcatag tcctttttat gaataaacgg tgttcaatca gctgaccctc
    13201 ggtattactc aacaaacggc aaaatatggg gagctatttt tcctttgtct tctctaatac
    13261 tcaggtcaaa acgctgattt cacaacctct ttagcctact attgaaaatt acaacttact
    13321 tgctgcttct tcatcgatga tcacaacaac attgtcgtga ttttgcaata cacttgctgg
    13381 caaatgattc gttacaggtc cttcaatcat ccctttgatt gcatcagctt tgctttcgcc
    13441 aaatgccatc aagacgattt ctttactttt cataattgaa ccgattccca ttgaaacagc
    13501 ttttgttggt acatcttctg ctttatcgaa gaatcgtttg tttgcattga ttgttgattc
    13561 tgttaagtca actactgaag tcgttccgtc aaatgaagca ccaggttcat tgaaaccgat
    13621 atgtccattt tgcccgattc ctaagatttg gatatcgatt ggatgtgcat cgatgatttg
    13681 atcatacttt ttgcatgctg cttccagatc ttctgctttt ccatctggta caaacgtttc
    13741 tttgaatggt tttttatcaa ataattggac atccatgaaa tgacggtagc tttgttcatc
    13801 tgaaccgcct agtccaacgt actcatctaa gtttacagaa gtcatttcac tgaaatccaa
    13861 atcgcttgaa gtcatttctt tatataaagt aactggtgtg cttcctgttg ccaatcctaa
    13921 tacttttgca cctttgttca taccttcttt gatgatttca aatgcttttt ttccgccttc
    13981 ttcagcgttt tttacacgaa tgatttccat agtgattgct cctttatatt ttggtatagc
    14041 ccaattatag cattcttttt ttctttttac aataattagt atagaccaaa ttgcattttt
    14101 ttcattttct tgacaataaa taggaatccg tgttaggttt cataagatgg ttcaatcaaa
    14161 caatccatgt tgcatgaaaa ccaagcaagt gattcactgt ggacgcttta tgtctgcagt
    14221 ttttttatga aaaaggagtt attatgagta tactgacatt aaacaacatt acccagcaat
    14281 ttggcgacaa aatcctctat gaaggtgtcg atctgcaatt aaatgctggc gaacatcttg
    14341 ggctgattgg acaaaacgga gccggtaaaa gtacattgat taaaatcatc actggtgaga
    14401 tcttaccaga tgacggacag atccattggc aaaaaaatat tcacaaaggt tacctcgatc
    14461 aatatgtgga agtcgatgaa acattaacaa tcgaagaatt tctaaaaact gcgtacgcaa
    14521 aagaatacga aaaggaagaa aaaattgctt ttctttacca aacatatagc gagaccttcg
    14581 atgattcctt gctggaaaaa gctgggaaac tccaaacgga attagaccaa ggagtgtttt
    14641 atcaaatcga caccttagtt gctgagatga gcagcgggtt ggggatcgat gtcttaggtt
    14701 tagattcact gttgaaaaat ctaagtggtg gacaacgttc aaaggtgatt ttagcaaaac
    14761 tacttttaga aaacccagat gttctgatct tagatgaacc aaccaatcac ttagatgatc
    14821 agcatatcca atggctgacg cagtttcttc aggattttga cggtgcgtat atcgtgattt
    14881 cccatgacca agaatttctt gatcagatca ccacccatat cgcagacatc gagtttggaa
    14941 agattactaa gtatactggc catctaaaac aagcattgaa acaaaaggaa caaaatcgcg
    15001 aaagctattt gcgccaatat catgctcaac aaaaacaaat cgaaaagacc gaagcttata
    15061 ttcgaaaata caaagccggt tcccgatcaa cgatggcaaa aagccgacaa aaacaattag
    15121 ataaaatcga acggctgacg cctccagctt cagcaagtaa agctgtcttt gattttccat
    15181 tctcgcctat tgtcacgaca ttagcagtgg aaacaactga tttagtcatc ggatatgatc
    15241 gaccgctact tgcacccatc aatttgacca tccgctttgg tgaaaatatt gccattcgag
    15301 gcttcaacgg gattggaaaa tctactttat taaaaacact gatcggtgag attgaaaaaa
    15361 taagtggcga tttccacttc ccagataaca caaaaatcaa ttacttttca caagatctgt
    15421 actgggaaaa tccattagaa acaccactac aatatttaag cagtcaattt ccaaaagcga
    15481 ctatcaaaga attacgtcgc caactagcta aagcagggtt agttaatcaa ttagcaagtg
    15541 aacctctcac tacattaagt ggtggggaac aaactaaggt gaaacttgca cagttgacaa
    15601 tgaaccaagg taatttactg attctcgatg aaccgacgaa ccatatcgat caagaaacga
    15661 aagaaagctt acaagacggg atacagaaat ttccaggaac agtaatcatc gtctctcatg
    15721 aacaagaatt ttatcaagat cttgtgcaac gagtcattga gattgaacca aaataaacgt
    15781 ttgattgaat agttgaaaaa aaggagctgt gacaaaagtt ttgtcacaac tccttcttct
    15841 gaataaatgg tggccaatta gctgaccttc ggtattagct caaaaaacgg caaaatatga
    15901 ggagctattt ttatttggct attcttatta cttgatgcag aacagctttt cacaacctct
    15961 tttcgtctat tttttatttt cgagatttct ctttccttta aaaacaactg tttgaaagaa
    16021 gaacgcacat ccttgaaaaa caagcccgct aaccgttaca cctaaccagc catactgctg
    16081 ccacattgtc gtccctagca atgaaccagc cgcacctcca ataaagtaca taaacataaa
    16141 tacagtatta tttcggttgc ttgctgcttc acctagccct tgtactcgtg tttgattggc
    16201 gacttgacca aattgattcc cgacgtctaa taaaataata gctaaaagca aaatggccaa
    16261 atggcttccg ccaaccaata aagcaataaa gcttattgtt tgcataacaa gtcccatata
    16321 cacgattttt ctttcagaat aagaatctgc cagtcgtccc acgataggtg cagcaactgc
    16381 tccagacaaa ccaaaaatcg ctaatatccc tgcttcgaat gttccccaat tgtaggcggg
    16441 actgctgata taaaaaatca acgtagacca aaagatcgaa aatgttccaa acatgaaaaa
    16501 tccactgact gccgcttctc ttaatagacg ttgagaagca actaaatgcg gcaaactttt
    16561 aagtgaatca aggtatgaaa cagctgtact actttgctgg acagaacgcg gcattttcca
    16621 gtaaagcaga agtgtaagaa ttccgactgc acataaagca aataaataga tcatccgcca
    16681 agaaaaaaga ctggcaacaa taccagatac cgtccgagaa agcaaaatcc ccacgagtaa
    16741 accgctaagc aatgtaccca tgaccttccc tcttgctttt ggtcccgcta gtaccgcacc
    16801 gtaaggaatg atgatttgcg gcacgatcga aagtaatcct attaaaaaag aagcgcatgc
    16861 aaataacgta aacgaaggcg caaaaaaagc ggccaacaga gagacggcag ataacgctgc
    16921 cattcgaatg atcaattttg gacgatccac cacgtcccct aaaggaacta aaaacagtaa
    16981 ccctaacgca tagcctaatt gggtcaacat cgtcaatatc ccgactgcac ttgtgctaac
    17041 agataaacta gctgctactt ttgttccaat cggctggatg taatacatat tggcaacaac
    17101 aacgccacaa gtgattgata atagtaaaat aagcgaagtt gttaaaggtt ttttttcatt
    17161 actcttcatt gatttccccc atttcctatc ttagtttaca acttatggaa aagattggaa
    17221 atagaaaaat acaactattc gccacactta ttatttgtgc ttttgttttc cttgtttttt
    17281 cttgcgatct ttataaatga agacaactaa ccctactagc acagtaacac ttgcaaccaa
    17341 cgtgactgca gttttgttat atccgtgaaa cagagcttct ccaccacacg catacaacac
    17401 agacgaaggg atgactccaa tcacgatcga caatatgatt tgctgtagag gcaatttcat
    17461 cgcatctgca gcaaaattga ccatagaaga tggaataacc ggtatcatat agcctaacat
    17521 tacacctatt tttggatgtt tcatttgtcg gattgcttgc acccaatgat tcgtttcggt
    17581 tttcttatct aaaaatttta agcgatgcat aaggaaaatt gcagtgatgt taccaagagc
    17641 attacccaaa atgttgatga tcgcacctgt cagtggtcca aagctcaaac cagcaatgac
    17701 tccaactact gaagtaggaa tacctggaac agcacacatc accgctgtca atacgatcaa
    17761 gagtatcgat gcaaaagtcc catgcgaacg aatatgtgcg agtagctctg ccttactcgc
    17821 tctcggattt aaaaataatt ggatgtctgt ctgatattct aaatacaacc gatagcccac
    17881 taccagtatc agaatgattc ccaacgagat caatatcaat cggattattt tctttttcat
    17941 atttcctcct gaaaaaaatc tatattcatt aaataatagt ttaacataaa aacaaaaaag
    18001 caccgaaatc caacatagga tctcagtgct tttaaatagt aaaaattatt taacagttac
    18061 agatgcgcca acttcttcaa gtttagcttt caattcttca gcttcttctt tagatacgcc
    18121 ttctttaact ggtgcaggag cgccatcaac tacagcttta gcttctttca agcctaaacc
    18181 agttgcttca cgaactgctt tgataacttt aactttttgg tctccagctg cagttaattc
    18241 tacagtgaat tctgtttgtt cttcagcagc agcagcgcca ccagcagcag ctacagctac
    18301 aggagcagca gcagatacgc caaattcttc ttcaatagct ttaactaggt cgttaagttc
    18361 taggatagtt gcttctttta actcagcaac gatgttttca atgttcaatg ccattataat
    18421 ttcctccgtt taattgttct tttttattta atgctttatg cggcaattaa gctgcatctc
    18481 catcttcttt gtctgccact gctttgacag cgtaagccac gttgcggact ggcgcttgta
    18541 gtacagatag caacatagat agaagtcctt cgcgatttgg caattttgcc aatgctgtga
    18601 tttcttccaa tgaagagact ttaccttcga tgataccgcc tttgatttct aatgcttttg
    18661 cttctttagc aaattcgtcc atgattttcg ctggtgcgac tacatcttcg ttactgaatg
    18721 caacagctgt aggtccagtg aatacttcgt ccatgccttc aaggccagct tttttagctg
    18781 cacgtgaaag aatagaattt ttgataactt tcatttctac gttagcatca cgaagttgtt
    18841 tacgtaaacg tgttacttca tcaactgtta atccgcggta gtcaacgact actactgatg
    18901 cagctgctgt aaatttttcg cttacttcat caacgattgc tgcttttttt gcgataattg
    18961 cttcactcat ttttgagttt cacctcctga attttgatgg aagagttttt tgcactgaaa
    19021 aggcaagtca cttttatagt tactttgctc aaccagtatt attcatcacc tattcacttc
    19081 gttcatagtg attctactcg ctttgctcga aaggaaactc ctttcgcttt gctcaaccag
    19141 tattgttcat catctcttca cttcgttcat agtgattcac aataaaaaac tctatgccac
    19201 cgcagacata gagggactat tgaatatatt caataaacgt cctcggtagg aaattaaggc
    19261 ttgatgccac ctactgtctt cggtacaagt taattattaa cctcaactag cttagcatgc
    19321 taaactagtt gagtcaagaa ttatttttca gttggatcaa tcaacattct aatatttaat
    19381 tagaaagaag cttggtcaac atggatacca ggtccaaatg ttgttgtgat cgttacattt
    19441 ttcatgtatt gacctttagc tgctgatggt ttagctttta gcaatacatc atggattgct
    19501 gcaaagtttt caactaattt ttcatcgtca aatgaaactt ttccgattgg tacatggata
    19561 tttccagctt tgtccacacg gtaagttact ttaccagctt tcacttcgtt tactgctttt
    19621 gttacgtcca ttgtaactgt accagtttta gggtttggca ttaagccttt tggtcctaat
    19681 actcgtccta gacgacctac agtagccatc atatcaggtg ttgcaacaac tacatcaaag
    19741 tcaaaccatc cgttttggat tttttgaacc atgtcgtcgt cacctacgaa atctgcacca
    19801 gctgcttcag cttcttttgc tttgtctcct ttagcaaaaa ctaaaacagt ttgtgtttta
    19861 ccagttccgt ttggtaatac aacagcacca cggatttgtt ggtctgcttt tttagggtct
    19921 acgttcaaac ggtatgcaac ttcaactgtt gcatcaaatt ttgcaatgtt tgtttctttt
    19981 gctaaagcta ctgcttcggc aacaggataa actttacttg aatcaacttt ttttaatgca
    20041 tcttgcattt ttttgctctt tttagccatt ttggttcctc cttgattgtg gttataacgg
    20101 ttgtacctcc cacgtgttct atatctttca atatagagcc aactgagaag ctgctgtctt
    20161 agggtgtata gattattcta cagtgatccc catgcttcgt gcagttcctt caaccatgcg
    20221 cattgctgct tcaacgttag ctgcgtttag gtcttccatt tttaattcag cgatttctct
    20281 tacttgatcg ctagaaactt tcgcaacttt atttttgttt ggttcgcctg aacctttttc
    20341 gattttagct gcttttttca atagaacagc agctggcggt gtttttgtaa cgaatgtgaa
    20401 tgaacggtct tcgtatacag aaataacaac cggaatgatc aaacctgctt gatcagctgt
    20461 acgagcgttg aattcttttg tgaatcccat gatattgata cccgcttgac ctagtgcagg
    20521 acctactggt ggagctggag ttgctttacc tgcaggaatt tgcaatttaa cgattttttc
    20581 tactttcttt gccacgagac atacctcctt aagtccgtga tgtggttaat tggagatgca
    20641 tatttctcct cccacgtttt atctgatctg aaaaaatcca gacaaataat gtgcaaaaca
    20701 atgcacactg gtacagtata gcaaatttat ttgttttttc aagatttttt tctgctattt
    20761 ttacattttg cttgaataaa cgctaaattt attctaaaaa aacaacaatt tttcgttctc
    20821 atttcttctt ttatgttaca cttgcgctag catggttcaa cagatgaaag caaacaataa
    20881 cacggttttt tagacccttg tacaaagatt cctacataac aaaatgaggt ggagaaaatg
    20941 aaagatttaa ggtatagaag tgtctttgat attattggac ctgtgatgat tggtccaagt
    21001 agctctcaca ctgccggagc tgctagaatc gggaaaatca tacgtagtat atttggcgaa
    21061 cagcctgatt ctgtagatat ttatctatat gaatcatttg caaaaaccta tcgggggcac
    21121 ggaacagata ttgcattagt tggcggcctg ttagggatgg aacccgatga tgaacgttta
    21181 gctgattctt tgaaattggc atatgaagcc ggtatggaag tcttgtttgt tcctaagagt
    21241 gaaaaagccg aacatccaaa ctctgtaaag atgcttctaa aaaaaggaac acgaaagctt
    21301 tcagtcactg gcatttcgat cggcggtggc aatatccaga tttctgaatt gaatggattc
    21361 aaaatttctt taagcatggg tactcctacc ttgatcgttg tccaccaaga tgttccaggt
    21421 atgattgcta aagtgactag tatactttct gagaccaata cgaatatcgg cactatgaca
    21481 gtgacacggg aatcaaaagg tgaaaatgcc attatgataa ttgaagtaga tgatcctcaa
    21541 gtagaagaaa cggtaaaaag actcaaacag ctgccaaata tcgacagcgt aaattatttc
    21601 gattaaggag ctaaaaaaat gtttttatcg attgaagaat tagtagatca agcaaaagct
    21661 tatccaagtg tagcagaatt gatgattgca gttgaaatgg aaatgagtgg ccgttcccgt
    21721 agtcacatca tcgagatcat ggaaaaaaac ctctcagtaa tggaacaatc aatcaacgag
    21781 ggaaaagaag gtgttacctc cgtcacagga attaccggtg gtgatgcaaa aaaattagat
    21841 gattatttaa atgaggcaga ctttttaagt ggagaaacaa tcttaaaagc tgtacgcaat
    21901 gctgtagctg ttaatgaagt caatgcaaaa atggggttga tttgtgctac accgactgcc
    21961 ggaagcgcgg gtgttgttcc tggtgtgctg atggctgtcc gagatcggct tgatttgaca
    22021 catgaacagc aattggaatt cttatttacc gctggcgctt tcgggttagt catcgcaaac
    22081 aacgcttcta tcagtggtgc agaaggggga tgtcaagcag aagttggttc tgcaagtgca
    22141 atggcagcag cagctttggt ttgtgcaaaa aatgggactc ctcatcaagc agcacaagca
    22201 gtagccatta cattgaaaaa tatgatggga ctgatttgcg atcccgttgc aggcttagtt
    22261 gaagtcccgt gtgtcaaacg taatgcttta ggctcttctc aagcttttat ctctgctgat
    22321 atggcattag cgggtatcga aagtgtcatt ccgccggatg aagtcgttgc tgcaatgtac
    22381 caagtcggac gtcaaatgcc gtcgattttc aaagaaacag cagaaggtgg cttagctgtt
    22441 acgccaactg ctaaacgact tgcggaagag attttaaata agagggcgtg ataaagctcc
    22501 ttaatttcga gtattaagag attagttatc ttcataacaa aaaacgaaga gaggactaat
    22561 tgcccttctc ttcgtttttt attaatccat caatttcgta ttttttactt catcgatcgt
    22621 ttttgttcct gcaagttgca tcgtgatcga caattctttg ttcaggtgtt caaaaacaga
    22681 tgttactcct tctgccccac ctagattcaa cccataaatc actggtcggc caatcgcaac
    22741 taagtcagca ccacttgcca gagctttgaa gacatgctct cctcgacgga caccagagtc
    22801 gaaaatcact ggtacacgtt tgttgactac ttcggcaatt tttggcaata cttcaaagga
    22861 cgcaggacct ccatctagtt gacgtccacc atgattggat acccagatac catctgcccc
    22921 tgcagagata gcgattactg catcttctgg cgattgtatt ccttttacga taactggaag
    22981 atgggtgatt tctttgattg ttttgatgtc atctggtgtc aagccttgtt ttgcagctgc
    23041 ataaatttct gcgattcctt ttccttcgcc attaccactt gcactttgtt cgctatacgc
    23101 agctaagtta ggcattggta atggaaattg gaattgattg atgacgtctt cttcacggta
    23161 accaccgagc gttgaatctg ccgttaaaat gatagcttta gcccctgctt ctactgcttt
    23221 gttcaaaatg aactcattga atctgtcgtc tttactcata tataattgga aaaactgcgg
    23281 tgcgcctggc gctgcatcgg ctgcgtcttt gattgtcgta tttgcataag tgctgatgga
    23341 aaagattgat ccagcagcag ctactccttt agctgtatca gcttcccctt tttcatgtgc
    23401 caatccttgg gccgctgatg gcgcttggat aatcggtgta tctaattcaa ttccgaaaac
    23461 agatgtatgc aaatcggctg agtcgattcc gcgtaatatc cgtggcatga ttttctttgt
    23521 attaaaagaa gtcgtatttt ctttcatcgt ccactcatct tcagaaccac cgcgaatata
    23581 gccaaaagct cctgcttcca tgcgctcttt tacacgacct tctagttagg caatgtttac
    23641 aatatcgatt ggatgttctt cattacttgt atgataagtc atagtagatc cttctttcat
    23701 cttcttgatt acatataaat catactaaac ttacaaaaag taagcaaaca tttactctca
    23761 gatactttta tcgctattct ttccaaataa atcgacttac aagctgatct acttcttggt
    23821 tttcatgaag catactatga gaggcatttt cacctgtcac tactttttcc tctatttcat
    23881 ttccgcgttg cttcaacaac gcatagaccg ctaatgcact gtttaacggt actgttccat
    23941 cactcaagtc tgtttcatct agttgaccag caatcaagaa aaatcgagtg gttataggaa
    24001 tattaccgat catttgctgg taatcttgat agcggttaga aacgacagca ggcccctttg
    24061 ctaactcatc tgtcagagac tgcgcactat catcgacaaa atcattaaaa ggcgcgccaa
    24121 ttgctgttaa tgtctgaact tgtggcaatg acgtatcctg tccatacgtt cctaaatagc
    24181 gtagtgcact aactcctccc atggaatgcc ccactatgtt gactttatct atgccgtagt
    24241 tttctttcag atacaaaaga caagttttga tccattctgc ttgattccac tcgttatttt
    24301 tattatcttc aaacaatact tggaccatcg gattgtctgc ttttccagac aaatctcctg
    24361 ttgcttgtat ttgtccatct gttcctactg ttaaaaccaa ttcttttact gcttgctgat
    24421 ttttttccaa acgccgcaac atccctttaa aggaattttc tgtcccgctg tagccgtgga
    24481 aaaaaagtgt tggaatagtg gttttttcta tcactttact ggattctgcc gttttttctt
    24541 tatcagaaac ttcagtagta tttatcttcg tcgtctggca accacttaac gcaaacaaac
    24601 tgataaggac taaagctgct gcagttgcac gtttgcataa atttttgatt ggttctgtca
    24661 tacacctctt cctttccata tagaaaaaag aaagacttga aaggccaatc atatgatcga
    24721 catttcaagt ctctttatta atcgatttta tctacttgat cgaaatcaag ttctgtactg
    24781 gtttcacgtc caaacatatc gatgttgact ttcaattttt ctttttctcc gtcaacttct
    24841 gttacttgtc cttctaatcc agcaaatgcg ccttcgatga ttttcacgac ttcgccaact
    24901 tctacttcta gatcattttg tcgcaggctc ataccgatag aacgcaagat atgattgact
    24961 tcttctggaa gtaatggtgc tggtttgctt ccggctccgt gtgaaccaac gaatcctgtc
    25021 acaccaggtg tgttgcggac aacataccat gaagcgtctg tcatgatcat ttcaacaagt
    25081 acgtatcctg ggaatgtttt atgaacgatt tctttttctt tcccattttt gacttcagtt
    25141 tctttttctt caggaacaac gacacggaaa ataaagtcgg ccattttcat actttgcgca
    25201 cgagattcga tatttgcttt tactttgttt tcatatcctg aatatgtatg caagacatac
    25261 cagttttttt caaaagattc cattgaaggc tcctcatttc attgtaaaat aaaaaaacct
    25321 cagtacaccc gaagtttttc tttcgcttca ttatagcact aaaagtacgt tgtggctagc
    25381 gagttatttt aaaatccagc caaataagct ttggatggct gtatccatta cgtaaaacat
    25441 caatccgaaa ataatagaag tttcgatgac tactaacgta tctttacgga gttgttttct
    25501 gcttggccaa gttacttgtt tgatttcatc ttttacgctt tttagaaatt tcatgagaca
    25561 acctcccttg ctactgttta tttcgtttct ttatgtaatg tatattgatt acaatattta
    25621 caaaacttat tgatttccaa acgttcgccg ctttttcctt cactgactga ttttgtgtag
    25681 ttgcgagacc cacaaacgga acaagcgagt gctgcttttt tctttgccat ttacttctgc
    25741 ccccttgctg agaatcagac ttatacttca taacagtatc acgtaacttt ttacttgtca
    25801 atttgtgaaa taaactatct attgttttgg ataaaattat gatatgatta atttgaaatt
    25861 aagctaaaat gagacaattg gaggtatagc gatgctatta aaaacacttg tatataagaa
    25921 aaaagatctg acaaccgtta cagagactag tacattagaa gaagcattaa aaattttaga
    25981 aacttccgga taccgttgtg tgccgatctt agattcttca ggtaatattt tccgtggaaa
    26041 catttacaaa atgcatatct atcgtcataa agcaaatggc ggtgatatga cgcttcctgt
    26101 cactcatctt ttgaaaaacg ctacaaagtt catttacctg gatacttctt tcttcaaagt
    26161 attctttacg atcaaagagc ttccttatat tgctgtcctt gacagtgaaa atcattttta
    26221 tggtattttg acacatagta cgttgcttaa tatgctctct caatcttgga gcgtagaaca
    26281 aggaagctat gtactgacaa ttgcttccac aggaaagcaa ggagatttgg ctgctattgc
    26341 aaaaatcatt tcaaaacaca gcagcattgc cagctgtatt actcttgata tcgaaaaaga
    26401 cgaatacatt cgacgtacat tgatcacgct accggctaac actgaagcga aagtatgtga
    26461 aacgatcgtc aaccacttag agaaaaagaa ttataaagtg gtagaaattg aaaatttgca
    26521 aaaccaagaa gcataatcaa aaagcgaaaa aagaaaacag ctaatctgct ttcttttttc
    26581 gctttttata attagacacg cttttcaaaa tcaagcgcgc gatctaaata atacatcaat
    26641 ggtgctgaaa cagccatgac gataaactca cttaatgcaa gcgtgccata ggttgtccaa
    26701 aatgcttggc cacctgttgg aactaacata taagcaatca gtcccatgct gatggtaaag
    26761 aagatcgtgt tcaatactaa acgcatcttt acatttttca ctttgttttg caataaagct
    26821 gtcaggccta aagaaagcaa tgtttggccg ccaccaaaaa ccacatccat gataccaaaa
    26881 ccaaagaagg cattatagac gatgaccccg cctaaaactc cccaaagcaa tttacggtta
    26941 aagacaacta aatgattcaa actttctgaa atacgaaact ggatcggccc tgaggataca
    27001 ggcgcaacta aaatagttaa cgctagataa agagccatga tgatgccatt tacaacgatt
    27061 acggataacc gttgtctgct tttcgttttt tgcattttct ctcctctttt ctcctagttt
    27121 ttttaacgcg ggatggttga tgaaccgcgg ttatgtgaaa caaacaataa ttataacaga
    27181 cttttcattt atttcaatcc gtcttatctg cttttaaaaa agcaaaagct taaacaatgt
    27241 aaacgtttgc taaaaatcgt gggatatggt ataaagtaag tgtaaggggt cataagaatt
    27301 cccagtaaag cagacgaagt aggatctgca agaacagaat tgttgtgaaa cttaaataaa
    27361 taaaaaagga tgtgggaatt tgagcaacct cttactagag aacggtctag caagcagctg
    27421 aagatctaag tggacatgcc gaaccttgga acttctcctt acgtaagtaa tggatcatgc
    27481 gcttgctagg cttttttgtg tttttcggtc ttcggacctt tttcattttc ctagacttct
    27541 gctataataa ccaagaatta attttgtaac agattttttt gaaaaaacaa gtttctttca
    27601 ttcaaaaaat agaaaaagct tgctaattat tggttaacca gcaaacagga gtattaaaat
    27661 atcttgtttt attgaatagc aggaggaaat catgaaattc cattatcata tattgatcaa
    27721 tccatcggca ggcagcggaa atggctataa agtagcagaa agaattttac cggtattaaa
    27781 aaataagcat attgactata cacttcatta tagtgaatac aaaggacacg atgctgagat
    27841 tgctgaaact ttggcaaaag aaacattgat tccttggata gaagaagaac agaaaacaat
    27901 cgatactttc ccccttttga tcatcgtagg aggtgacggc accttacatc aggtacttga
    27961 tactttctat cagatggaag tagaattccc agttgcttat attccagcag gttctggaga
    28021 tgattttgct cgaggggcag gccttccaaa aaatcccaaa aaaggacttc agctgatttt
    28081 agcagctcaa tcaccagaaa aagtccacat aatggcttat gaagaaaaaa taagtgaaaa
    28141 aaaaggaata gctgttaata atttcggtat aggattagat gcagctatcg tccatgcgac
    28201 aaatcattct tccacaaaaa agcgattgaa caaatacaac ttaggatcat tttcgtattt
    28261 attctctatt ctccgtgctt tattcactca aaaaggattt ccaattctgg tagatgcagg
    28321 aggaaaacaa ttaagttttt caaacgcatt tttatgtaca gcaacgaagc atcctttttt
    28381 tggcggagga atcgcgattg ttccaactgc tgatgcgtct aaaccagtca ttgattttgt
    28441 cgtggtcgaa cgaatcaatt tctttaaaat cttgtggctc attcttttac ttatacagaa
    28501 aaaacaattg aaatcgaaat atttccatca ctacacaaca aacagattac gtatcgtttc
    28561 aacaacaccg caacatggtc aagaagatgg agaagaaatg gaaaaacgac cttttgatat
    28621 cacaataacc acaactaaac agttgttttg gtgttaataa aagaggtttt gtcagaagct
    28681 acatctggaa caccgtttat tcggaaaaaa ggactgtgac acgacttttg tcacagtcct
    28741 ttttttacta tgcagttaat tctttgccca attgggttgc catcgatagt ttctttcttt
    28801 acccaaaata aattggatca ttgaaaacac cgcagcaaaa gcaactaaga cacaaccatt
    28861 gaaccaaaaa gattctgcaa atgtttgatt gtaactgagt gtttcactga tcaagttatt
    28921 attttgaaca aaccaatatg ttggtgtgaa tgccgctatt ttgctaacca tttctggcaa
    28981 gtattctgct ggtacaaaca ccccaccgat aaagcaactg cctgtgataa aaatatcttt
    29041 gatcccaccg ctggtttctg agttttttac caatgaagtg atacaagccg aaaagctaat
    29101 gatcggcaat aaaaacaaga aagtatttaa aatatgatac cataccgtta tatcccacga
    29161 ggtgtggatc actaacagaa ccattagaag taagaagcca ctgaacaaca gcagcgagta
    29221 actaatcaaa ctaaaggtta ctttgcgatt caagtttcgt ttggtaatgg gcgcactctg
    29281 gtttcgttta ctgatctctt tgcgattaaa tgctagattg atgacgctga aaccgctaaa
    29341 aatggataga aacaacccat aagacaagaa attaaaggtt gtgcccgtca acagcttttt
    29401 catccgctga ctatatcccg cacttagctc aacttctcca gtaaccgaga gtgccatttg
    29461 tgtctgttcc atagctgcat cgattgtttt atcttcttct tgaaacagaa tcagtgtttg
    29521 caaaaaggtg ttcacttgct gtgtaacaac tgttttagaa aaggcatctg ggcgactctg
    29581 tatcttgatc gtcggcatct ttcctacttc gacttgttcg gtaaagtctg caggcagatg
    29641 taagataatg tttacacgat taaaataaag agcatcatcg atttcttttt gtgaggttcc
    29701 atccaatgta acgactgttt ccttgtcatt caaatattta cgaaggccat cgactacagg
    29761 cgactcttct tcactaatca aggcgatttt cgcatcttgc agagaggtat tttcaacatc
    29821 aatattttgc gcaaaaaaga atgtggcaac aacagtgata attacaccta tcagtaaatt
    29881 cgatttattt gctttaagca atgtccaaat cgttttataa agcgtcataa cgcacccctc
    29941 tttccatcca agcatttcct aacgcaaaaa ggaaaataaa tccgatcaac catagaagat
    30001 tggtataaaa actagccaaa tcagtgtaga aataaagttt atacaaactt tcgctgatca
    30061 agttgacgag atttaattga ccaacaatcg gaatatgaag atcaatccaa tacttcactt
    30121 gttccgaccc catcatacca gcaaaaaagc tcatcgcaat cgtcactgaa atcaagatgc
    30181 tatccttttg caccagattc atttttggta tcaaattacc aaccaatgta cctaacaaaa
    30241 tcgcacacaa cgaccccaga gcggtaacaa tcatcaacca ttgccaacgt tcaccaaagt
    30301 ctacttgata gataaaacga aagacagcta acataatata aatctctgtc aaaacaatcg
    30361 taaagcttgc tgccaaatta gcgattgaaa ctaacgattg ctttctagga atcaaggaca
    30421 agcgaatacc atttgacgat tgatttgctt gctgatcctg tacattgcgg accccccaca
    30481 tcgtcccgta gagaatcgcc attccaatca gagtgaagaa ataaaaactt ttgaaactca
    30541 tattacgacc tgcatgaact tcttgaaaag atacttcttg ttcaaaaaca gtcatgatgg
    30601 gcgcgagatc aacgttctcc acttctgcca ctttactcga aattatacca atacgctgta
    30661 aaaattgatc catgacgttt ttcatcaacg tctgactcat tcctgcttga cccacatgga
    30721 gcgaaacaga tgaaccatca atgagataaa aaccagccaa atcatctgca tttagctttt
    30781 cattcgcttc tacttccgat agttcctgta cttcaaataa tggtttatca ttgacttcga
    30841 cttgttctaa gactgtggta aaattttccg aaagcgctgt ttgatccgct ttgattacaa
    30901 ttccagtatt aatcgtttcg agattgccac cttgatcaat ctcgccaaag gccgccataa
    30961 acatcaatcc taaaagaatt ggaaaggcca atgtccaaaa caacatggat ttatttcgca
    31021 gcagtatttt tgtgcgatat ttataaaaat gccaaaacat tatttcccct cctctagtct
    31081 ctcaaatcct tgccagtaat ctctaaaaag acatcattca aggacgcttc tttggttgct
    31141 atttttccgt aactgatctt ttcttcttgt aagattgtaa gaatcggcaa caatactgta
    31201 tttagttcag tagttgttac ttggagctga ccttttttat aagcgattcc atcagaagct
    31261 attgttcgct gacaacacgt tttctgggag taatgggatg tcgatcgtca aacgatccgc
    31321 cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct gtccttgatc
    31381 catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg ttgtatagac
    31441 aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat tccgactttg
    31501 ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt gggcaatccc
    31561 acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac gaaacgaaac
    31621 atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc ttttctcttt
    31681 ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta gttcgtcaaa
    31741 gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat tttcaggagt
    31801 cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag aaagcataca
    31861 gttgatggca gtcgatttcc cactgccgtt tggtcctaac agacctaaga cttctccttc
    31921 ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt tgactaattt
    31981 atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat ctgactataa
    32041 taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca tttgtcacaa
    32101 tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt ctactggtta
    32161 tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc tatttattga
    32221 tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat tggattttcc
    32281 aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt ctgccagcga
    32341 cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg ttaggttttt
    32401 tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc gtaattttgc
    32461 tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt gagaaaaagt
    32521 acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa caaaataaag
    32581 cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa cggaaccgaa
    32641 ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt ttacaaattg
    32701 gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa aatttaagtg
    32761 ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc catgagacat
    32821 cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct tctgttacga
    32881 ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc ttaatggtca
    32941 tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt gttttacatt
    33001 ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc agcccacaaa
    33061 aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa gaacaaaagg
    33121 gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt ttaccaaggg
    33181 agggacacca atgataacag tagtcattat tgagatgatc catttgtgac gaaatcgtta
    33241 caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca ttgtgccaag
    33301 gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga catccgcatg
    33361 cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc
    33421 cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt
    33481 gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct
    33541 tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag
    33601 aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc
    33661 atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt
    33721 gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc
    33781 acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa
    33841 cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc
    33901 gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg
    33961 gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg
    34021 attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca
    34081 tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt
    34141 cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca tatcacactg
    34201 aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc
    34261 aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat
    34321 ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt
    34381 ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt
    34441 ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt
    34501 ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag
    34561 aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga
    34621 tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg
    34681 cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca
    34741 aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt
    34801 cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt
    34861 ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc actttatctt
    34921 cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg aatacattca
    34981 attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc
    35041 aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta
    35101 acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac
    35161 ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca atttgataag
    35221 catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc
    35281 cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct
    35341 gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag
    35401 gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa
    35461 tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca
    35521 aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc
    35581 ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg
    35641 ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat
    35701 ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt
    35761 tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag
    35821 cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct
    35881 tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg
    35941 aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt
    36001 gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga
    36061 tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg
    36121 gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc
    36181 gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt
    36241 tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca
    36301 aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac
    36361 gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca
    36421 tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga
    36481 ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga
    36541 ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt
    36601 cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc
    36661 cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct
    36721 ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat
    36781 tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg
    36841 gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct
    36901 aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca
    36961 gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc
    37021 tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa
    37081 agtgggccat ctttatgttg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt
    37141 gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc
    37201 aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa
    37261 gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc
    37321 tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct
    37381 ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta actttgtggc
    37441 aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc
    37501 ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact
    37561 ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta
    37621 gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc
    37681 aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc
    37741 ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca
    37801 tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta
    37861 cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca
    37921 ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc
    37981 tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt
    38041 gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt
    38101 atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg
    38161 tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca
    38221 ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt
    38281 ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa
    38341 taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg
    38401 ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg
    38461 tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt
    38521 ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg
    38581 acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga
    38641 gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa
    38701 tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga
    38761 ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat
    38821 ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag
    38881 cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga
    38941 ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg
    39001 ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat
    39061 caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg
    39121 attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt
    39181 ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc
    39241 tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac
    39301 tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac
    39361 ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct
    39421 ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat
    39481 aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg
    39541 gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa
    39601 ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt
    39661 cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc
    39721 ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa
    39781 ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag
    39841 aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg
    39901 gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc
    39961 aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa
    40021 tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat
    40081 caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga
    40141 ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac
    40201 ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt
    40261 cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa
    40321 cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga
    40381 agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg
    40441 tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta
    40501 ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag
    40561 cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat
    40621 cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt
    40681 cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg
    40741 cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt
    40801 gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt
    40861 acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg
    40921 cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg
    40981 acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag
    41041 cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta
    41101 ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt
    41161 taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt
    41221 gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt
    41281 cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac
    41341 caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa
    41401 aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca
    41461 atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag
    41521 cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag
    41581 ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc
    41641 cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg
    41701 caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata
    41761 ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg
    41821 ctttgcaaaa agcatcaaac cagatgtatc ccgatctagt cgcgtcacca catggattac
    41881 ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt
    41941 tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg
    42001 ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc
    42061 ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc
    42121 tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt
    42181 tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc
    42241 ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat
    42301 gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc
    42361 ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt
    42421 ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa
    42481 acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga
    42541 tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca
    42601 atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg
    42661 tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt
    42721 catccaaata actgatccga acatccagca agggataact aacactttgt tcccggttcg
    42781 ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta
    42841 aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga
    42901 acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat
    42961 ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct
    43021 ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct
    43081 ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac
    43141 cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca
    43201 gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta
    43261 taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt
    43321 tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga
    43381 taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc
    43441 atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac
    43501 atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc
    43561 cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt gacaaattca
    43621 atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc
    43681 aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct
    43741 gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt
    43801 actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc
    43861 gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac
    43921 gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt
    43981 tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc
    44041 gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca
    44101 acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt
    44161 tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa
    44221 accggaaagc ttacaacaaa acgggctgaa ttccctattg aagaaggact tttagctatt
    44281 gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca
    44341 tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct
    44401 gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca
    44461 aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta
    44521 gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt
    44581 gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa
    44641 gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat
    44701 ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa
    44761 cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt
    44821 caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat
    44881 gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg
    44941 aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa
    45001 aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc
    45061 tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc
    45121 acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat
    45181 acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaaa
    45241 aatacgtcga ctcccttaca agagagccga cgtatttttt tcgtttctat tcgagaaaat
    45301 caaaaataga aagccttata aacgatcgat caattcttct aattcattta gacgttgttc
    45361 aaacatcgac attgcatctt caatatatgc agcctgtgtc atatcaactc ctgctttttt
    45421 cattacttcc acaggataat cgctgttacc tgcttttagg taagccaagt agttctctag
    45481 tgcctctggt tcctggttta gtattttctt cgccagtgct gaagcagcag aaaagccagt
    45541 cgagtattgg aaaacatagt aattataata aaaatgcggt atccgtgacc attcgaattt
    45601 aatttctggg tcttcttcga ctgctggacc ataatatttt gcattcaatt taccataact
    45661 atcacttagg tattcactag tcaatggcac acctttttca tcttccgtat gcatgaaatg
    45721 ctcgaattca gcgaattgtg tctggcggaa aactgttcct ttaaacccat ccaagtaatg
    45781 gttgagtaca taagcccgta cacgagggtc tttttctgtt tccaataaat actccgttag
    45841 gatattttca ttcgttgtcg aagcaatttc tgctaaaaag atggagtagt cgccgtacac
    45901 ataaggctgg ttcgaacgag tgaaataact atgaacacta tgtcccattt cgtggacaag
    45961 cgtaaatagc tgatccagcg tatcatgcca attcaataaa atatatggat ttgtgtcata
    46021 gcttcccgaa gaataagcat cgcttcgttt ccctttattt tcgacaacat cgatccaacg
    46081 ttcagagaat gctttttcta cgatggccat gtattcttca cccattggtt tcagtgcttc
    46141 taaagctttt tcttttgctt cttcgtacgt aaaggtaatt ggagcttccc ctaagaccgg
    46201 tgtataaaga tcatacatgt gcagtttttc cacttctaat aaacgtttcc gtaattccat
    46261 gtatcgatgt aacaaaggca aatgcttgtt taccacgtct accaaagtat cgtatacact
    46321 ttcaggaata tgattattgc tcaaagacgc ttctctggca gagctgtaat tacggacttt
    46381 cgctttaaaa ttatgtcctt ttatatgtgt gcctaaagta gaagcaaatg tatttctaaa
    46441 ttgttcgtaa acactgtaca atcccttaaa tgctgcttcg cgcacccttc gatccgtgct
    46501 ttctagcaac tgaccataca cgccatgaga taattggact atttcaccat tttctccttc
    46561 aatcgttgga aaaactagat ctgcattatt caaaacagca aatgtatcac ttgaagcatc
    46621 aaagatttca cctgctccag caagaagaga ttcctgctca gcagataaga catgggctcg
    46681 attatctact atttgctgga tataatggcg atagacttcc aattttggtt cttctttgaa
    46741 atattgccaa atctggtcat ctgacaattg caatatttct ggttcaaacc aggaaacggc
    46801 ttcactaact ttcgaaaaca gactgcttgc tcttgcataa agcgcttggt aatctgtatt
    46861 tccagtgtct tgatcgtttt taaggtgcgc atatacataa atgacttcag tttggcgata
    46921 aaccctcaat acgaattcaa tcgcatttaa aaattgagaa gcgccttgat caagtgttcc
    46981 tttgtgtttt tcagattgtt ttaactcttc tgataattcc aaatatttct catcaaactc
    47041 ttggtcgctt gaaaagatct tggtcaagtc ccaagttaaa ttttcaggca attcttctcg
    47101 ttttggcaac tgctttactt ccatgaaatc cactcctttt cttcccttag ctctatctat
    47161 caaaatagat catagtctaa catccacatg tcacagcatc taacttttct actcattcat
    47221 gtgtctgctt ccatcaattt tagcataact aaatcttgtt ttacatagaa aaccgattcc
    47281 tagcctattt ttatacttac tattttttca aagaagacaa gtgtatgcat tcgttaaaaa
    47341 actgctgata gaccatctct tcatcaatca taggaaaaag ccattccctt ttatgttctt
    47401 ttatttggca aagccatgag ttgaaatcag gaactttctg gttttccaag gcttcttcgt
    47461 acaacattcg ataaagaaaa acctgttctt gtaaataaaa gaaaaaccga cttttttgat
    47521 agatccacga tgatagatgc aaaagatgtt tatgacgcaa gtagcattgt tcttgtatgg
    47581 atactgtatt cttttgcttg tgaataagtt ggcgtgtcag ccatttcttc ccatcttcac
    47641 tcactttttc tatttttttc atttggttca ttttaatttc gttactagtg aatatttctt
    47701 taaggtccct actagaaaaa gtccagcagc tactgcaaaa ggaaatatgc cctgatacag
    47761 tctctgtaat atgatgatac aaataaagct tttgtttctt gagatcagct ttccagcaat
    47821 gcactcctct ttttctatta tagtagcagc aacttttttc tatcaatgag aattgcgatt
    47881 gtccaagaaa agaattacca agtatccacc atacttggta actgttattc aaataatttt
    47941 gggttctttc aataaatctc tggtgagaca gtctagaaca ttggatttct attgctagat
    48001 tcgccaacaa aatatccggc ctttgccgca acctcggcaa ataggcttcc aaaaatactg
    48061 gttctactga ctgtcccagc caatccatga agcattcctt taactgtaag tgctcttttg
    48121 attctctttc actaaagacc gaacagttat ctgatttttg atgggcaaaa tgagcacatt
    48181 ttttctttcc ctttttcaaa atcactcttt ttcgacagcc acgacaataa tatttctttc
    48241 ctttttctgc atgtttagca aaacagcact tattatattc attcattgca agcagcattt
    48301 ttctccctct gaacttattt acgtctaaga atttatttac acgaaaaaag agggcgtgaa
    48361 aaagctattc tgcatcaagt aataagaaca gctaaacaaa aatagttccc aatatttttc
    48421 gtttggttgg gcttgttacc gcagatgcaa gcttttgaac acatttatac gaaaaaaaga
    48481 ctgcgacaca atttttgtca cagtctctta ctataatgct gatttataca aaataaaatt
    48541 tcgttcgctc gatagcatta cgcgccatca gacattgtcc atattcattc aatgtttctg
    48601 gtgtacgatc gctcttttca gcaaactcca aaattcgagc aatctgattc tctacatccg
    48661 cttggttgag attttccatc cagaagtgaa cgactaggta atagcgctct tcgaataaat
    48721 acaaatcagt ccaagcagac tctagttcga catctgttgc aagttggatc acttgttcaa
    48781 aatcttcaaa agcaaaagtt gcttgtcttt cctgttcttc tagggcgctt ccagataatt
    48841 cttcctccgg atcgctgcca ataatctgct gacgaagaaa gtcactcaca tcttctgaat
    48901 caacagtaga atcttctgat tgagaaattt cttcatccgg aagattttta ctgataaaca
    48961 gttctaatcc gtctcctttt ggcaaaactt ggaaagtgac agcttcgctt cctcggaact
    49021 cctcttcgat atcaacttct tccaaaatac tataaaagaa attttcgatt tctttgtgat
    49081 tgccaagtaa atccaaaaat gaaacgcccc gttcctctaa atcttcatga ccaattagta
    49141 cacggatcgt attttcatta atatgttcca tttccatttt gctacacctc actttgccac
    49201 aatgtttaat atagattcat tgtagcgaaa tcagcttaaa tgtaaagaaa aaaaatctcg
    49261 ctgttaagcg aatttaataa aaccagcgga tttttcaacc tttcaagcta tcttatttaa
    49321 ctataacatt tttggcagac gaatactata tagccgactt ttcagctaat tttccctctc
    49381 tatttttcgt gcaatcatca tcttctacta cctttttata catctaatca agaatacttt
    49441 ttgtaaaaac aaaaaaactt ggaaaaacta tctttgtaat agt
//
LOCUS       DAXLPY010000014        47917 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.014, whole genome shotgun sequence.
ACCESSION   DAXLPY010000014 DAXLPY010000000
VERSION     DAXLPY010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.014"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(38..1189)
                     /locus_tag="ACF3UF_000897"
     CDS             complement(38..1189)
                     /locus_tag="ACF3UF_000897"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFD3671044.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="ACF3UF_000898"
     CDS             complement(1202..1639)
                     /locus_tag="ACF3UF_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3671045.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="ACF3UF_000899"
     CDS             complement(1654..3420)
                     /locus_tag="ACF3UF_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFD3671046.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="ACF3UF_000900"
     CDS             3684..4361
                     /locus_tag="ACF3UF_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3671047.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="ACF3UF_000901"
     CDS             4364..5491
                     /locus_tag="ACF3UF_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671048.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="ACF3UF_000902"
     CDS             complement(5691..6131)
                     /locus_tag="ACF3UF_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3671049.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="ACF3UF_000903"
     CDS             complement(6142..8175)
                     /locus_tag="ACF3UF_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFD3671050.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="ACF3UF_000904"
     CDS             complement(8177..9880)
                     /locus_tag="ACF3UF_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3671051.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="ACF3UF_000905"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="ACF3UF_000905"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFD3671052.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="ACF3UF_000906"
     CDS             complement(10963..11988)
                     /locus_tag="ACF3UF_000906"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFD3671053.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12197..13066)
                     /locus_tag="ACF3UF_000907"
     CDS             complement(12197..13066)
                     /locus_tag="ACF3UF_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3671054.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="ACF3UF_000908"
     CDS             complement(13525..15417)
                     /locus_tag="ACF3UF_000908"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671055.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="ACF3UF_000909"
     CDS             complement(15414..17141)
                     /locus_tag="ACF3UF_000909"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671056.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="ACF3UF_000910"
     CDS             complement(17157..17807)
                     /locus_tag="ACF3UF_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFD3671057.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="ACF3UF_000911"
     CDS             18011..18307
                     /locus_tag="ACF3UF_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFD3671058.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18479..19099
                     /locus_tag="ACF3UF_000912"
     CDS             18479..19099
                     /locus_tag="ACF3UF_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFD3671059.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="ACF3UF_000913"
     CDS             complement(19191..20357)
                     /locus_tag="ACF3UF_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3671060.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="ACF3UF_000914"
     CDS             complement(20369..20722)
                     /locus_tag="ACF3UF_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFD3671061.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="ACF3UF_000915"
     CDS             20850..21872
                     /locus_tag="ACF3UF_000915"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFD3671062.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21891..22052
                     /locus_tag="ACF3UF_000916"
     CDS             21891..22052
                     /locus_tag="ACF3UF_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671063.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22311..22745)
                     /locus_tag="ACF3UF_000917"
     CDS             complement(22311..22745)
                     /locus_tag="ACF3UF_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671064.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="ACF3UF_000918"
     CDS             complement(22855..24714)
                     /locus_tag="ACF3UF_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD3671065.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            24715..24855
                     /locus_tag="ACF3UF_000919"
     CDS             24715..24855
                     /locus_tag="ACF3UF_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFD3671066.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(24832..25992)
                     /locus_tag="ACF3UF_000920"
     CDS             complement(24832..25992)
                     /locus_tag="ACF3UF_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3671067.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27723)
                     /gene="araA"
                     /locus_tag="ACF3UF_000921"
     CDS             complement(26299..27723)
                     /gene="araA"
                     /locus_tag="ACF3UF_000921"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFD3671068.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27739..28437)
                     /locus_tag="ACF3UF_000922"
     CDS             complement(27739..28437)
                     /locus_tag="ACF3UF_000922"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFD3671069.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28394..30055)
                     /locus_tag="ACF3UF_000923"
     CDS             complement(28394..30055)
                     /locus_tag="ACF3UF_000923"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFD3671070.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30273..31673
                     /locus_tag="ACF3UF_000924"
     CDS             30273..31673
                     /locus_tag="ACF3UF_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFD3671071.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31925..33004)
                     /locus_tag="ACF3UF_000925"
     CDS             complement(31925..33004)
                     /locus_tag="ACF3UF_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3671072.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33090..34049)
                     /locus_tag="ACF3UF_000926"
     CDS             complement(33090..34049)
                     /locus_tag="ACF3UF_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFD3671073.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34061..35572)
                     /locus_tag="ACF3UF_000927"
     CDS             complement(34061..35572)
                     /locus_tag="ACF3UF_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFD3671074.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35594..36157)
                     /locus_tag="ACF3UF_000928"
     CDS             complement(35594..36157)
                     /locus_tag="ACF3UF_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFD3671075.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36163..37026)
                     /locus_tag="ACF3UF_000929"
     CDS             complement(36163..37026)
                     /locus_tag="ACF3UF_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671076.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37040..37936)
                     /locus_tag="ACF3UF_000930"
     CDS             complement(37040..37936)
                     /locus_tag="ACF3UF_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671077.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38111..39400)
                     /locus_tag="ACF3UF_000931"
     CDS             complement(38111..39400)
                     /locus_tag="ACF3UF_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3671078.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39372..40889)
                     /locus_tag="ACF3UF_000932"
     CDS             complement(39372..40889)
                     /locus_tag="ACF3UF_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFD3671079.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41087..41977
                     /locus_tag="ACF3UF_000933"
     CDS             41087..41977
                     /locus_tag="ACF3UF_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFD3671080.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="ACF3UF_000934"
     CDS             complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="ACF3UF_000934"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFD3671081.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42886..44358)
                     /locus_tag="ACF3UF_000935"
     CDS             complement(42886..44358)
                     /locus_tag="ACF3UF_000935"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFD3671082.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44995..45357)
                     /locus_tag="ACF3UF_000936"
     CDS             complement(44995..45357)
                     /locus_tag="ACF3UF_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFD3671083.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45580..46332
                     /locus_tag="ACF3UF_000937"
     CDS             45580..46332
                     /locus_tag="ACF3UF_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3671084.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46472..47395)
                     /locus_tag="ACF3UF_000938"
     CDS             complement(46472..47395)
                     /locus_tag="ACF3UF_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3671085.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47410..47682)
                     /locus_tag="ACF3UF_000939"
     CDS             complement(47410..47682)
                     /locus_tag="ACF3UF_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671086.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        13960 a         9948 c         8261 g        15748 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgc
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttattat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaactttc attataggct actgcaacat ccatccaatc
    27241 agcaatctct ttttggatct caggtcgttt ccagtagcca acgacgattt tattttgttt
    27301 atttaatcga gcattgatga acccatattc gcggtcacca tgagcggatt gatttaaatt
    27361 catgaaatcc atatcgatcg ttttccaagg aatgctttcg ttatattgcg tagctaaatg
    27421 aagcaatggt ttttgtagaa gctttgtccc gcggatccac atttttgctg gtgagaaagt
    27481 atgcatccaa gtgatcacac ctgctacttc ttctcgataa ttgacctctt tcatgatttt
    27541 tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg attggataag gcaattggcc
    27601 attttcattc agttcatcga ccatttcttg tgcatgtttc tttacttctc gcagtgcttc
    27661 ttccccatat aaatgctgtg atcctacaac aaaccaaaat tctttttctc caatattcaa
    27721 cataattagc cactcctttt atttgttttg tccgtaatac gcattttttc cgtgttttcg
    27781 taaataatgt ttatctaaaa tccgttgagg cagctcttct gaaaatgaat tgagctgtct
    27841 ggtaaataaa ttcatcttgc atacttcatc tagtacgact gcgttcatta ccgcactttg
    27901 cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa agtacccctg gaattgctaa
    27961 gggatcaatt ttgcgttctt tgaatgtttc tatgataact tttcctgttt catattcgta
    28021 cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt
    28081 atctgcatgc gtcgtcccca tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc
    28141 ccatgtcgag tgagtatgga cgattcctcc gatttgagga aatgaacgat ataaaacagc
    28201 atgagtaggc gtatccgaag agggattgag tttaccttca atgatatgat tgtccaagtc
    28261 cacaacgacc atgtcgtctg ctgtcatctc ttcataactg actccgctag gtttgataac
    28321 gaaatatcgt gtttcaggat caaaagcgct cacatttccc catgtatatt tgacgagtcc
    28381 gtgtttaggc aagtcaagat ttgcttggta tacttcttct ttcagttgtt ccagcatttt
    28441 ctatcactcc tttttcttgc aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac
    28501 ggtaacgtct cataaatatc tgatagcctg ctatttcttc tgctgaaggt gtgatggtga
    28561 ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc
    28621 gatccatcat ataggctgct aataacgcga ttccccacgc tccaccttct ccggctgtgt
    28681 ccatcactgt aactggtgcc tccatagcag atgctagaat ccgctgtcca acttctggtg
    28741 ttttaaaaat ccccccatgc cccactaaac gatcaatttg gacattctca gatttcaata
    28801 tatccattcc gattctcatt gcaccaaaag cactggctaa atggatccgc atgaaattcg
    28861 ctaaatcaaa acggctacct ggtgtacgta caaataatgg ccttccttca tttactcctg
    28921 taatgttttc accggaaaaa taaccataag aaagtaatcc cccgcaatcc gtatcgcctt
    28981 ctagcgcttt gttgaataat accgtgaata atttatctct gcttatctcc atacccaaag
    29041 aattggtaaa ttcttcaaaa atactgaccc aagcattgat atccgaagag cagttattcg
    29101 tatgaaccat gcctactagt tctcctgaag gtgtagtgac catgtcgatt tccggatgga
    29161 cattttctag ttctttttct aatacgatca tagcgaaggc ggaagtacca gccgaaatgt
    29221 tccctgtccg tttggctaca ctgttcgtag cgaccatacc ggttcctgca tccccttctg
    29281 gcggacaaac cgggattcct ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg
    29341 attcgcttaa cttgccagct tcttctcctg ctactagaac tttaggcaaa atgtgatcca
    29401 agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa aatatttttc atttcttgat
    29461 ggtaggtttt cgttgaagga tcgataggaa acatgcctga tgcatctcct acgcctagta
    29521 ctttctcacc agtaagctgc caatggacat aacctgcaag cgttgtcaaa aaattaattt
    29581 ctttcacatg ttcttcttta ttcaaaatag attgatacaa atgagcgata ctccatctct
    29641 gcggaatatt gtattgaaat ttttccgtta atattcgttc tgcttcttca gtgattgtat
    29701 ttcgccaagt acgaaatggt actagtaact gttccttgct atcaaatgct agataaccgt
    29761 gcatcattgc actgaaccca atcgacccga ttgtcgtaag attctcgcca tagatttcga
    29821 atacttctgc tgccattttt cggtaactga cgcgcagtcc tttccaaata tcttctaatg
    29881 aataggtcca gataccattt tctagtttgt tttcccactc ataactacca gcggcaatag
    29941 gagtaaaaga tgaatcaatc aatacagctt tgatcctagt tgatccaaac tcaatcccta
    30001 aagatgtacg accatctatg acatctaaca tactttgcgc atttacttcc ttcataatga
    30061 tttaactccc tccttctcgt caaacctgat caaaccgtct ttttagtagc gcttacaatg
    30121 attattgtat acttttgtac gtacatgtca agcggttatt tacaagaata caataaaaaa
    30181 cacttgtttt gtacgtacat aagttataaa atgaaattgc ttacaaaatc tgatcaaccg
    30241 ccttctcgaa attctagaag gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat
    30301 cgtttattta tttttttggc gcatttggcg gcattctatt tggatatgat attggtgtta
    30361 tgaccggcgc cttacctttt ttacagcatg attggggttt ggcaggtaaa gcttctttga
    30421 taggatggat cacgtcttcg gtcatgttag gtgcgatcct tggcggctct ttatctggtc
    30481 ttctttctga taagcttgga cgacgaaaaa tgattcttct ttctgcactt atttttatgg
    30541 ctggttctgt cctttctgca tctgcccctc acaatggttc ttattttctg attgcagcaa
    30601 ggattcttct aggtttagct gttggcgctg catctgccct agttcctgct tatatgtctg
    30661 aaatggctcc tgctagacta aggggaagat tgtcagggat caatcaagtg atgattgctt
    30721 ctggcatgct cctttcctat gttgcagatt atttgctaaa agtgttgcct gaaacgatgg
    30781 cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct gattttattt ttcggtgttt
    30841 tagctctacc agagtcaccg cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa
    30901 gagtattgaa ctatattcgg acaccaaaag aagctgaaca ggaattcgaa caaatccagc
    30961 tgaatgtcaa acaagaaaag acaaccggaa cttcttggca tactttgttt ttagaaaaat
    31021 atcgttcctt agtcattgcc ggtattggtg tagcagtatt ccagcaattt caaggagcta
    31081 atgctatttt ttactatatt ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg
    31141 atgcattgat gtggccgatc atccaaggaa tcattttagt tgctggttct ttgctctttt
    31201 tggttattgc agacaagttc aatcggcgaa ctttattgaa aataggcggt agcgtgatgg
    31261 gactttcatt catcctacca gctgttttag gaactgtact ggatgctcat acaaattcgt
    31321 tgttgattct cttgttttta tgtatttatg tcgcatttta ttcttgcaca tgggctccac
    31381 tgacatgggt aatcataggc gaaatattcc cactagctgt ccgcgggcga gcatctggcc
    31441 tagcctcttc ttttaattgg attggttctt tcctagttgg cttgcttttt cctgtgatga
    31501 ctgcttctat gtctcaagaa atcgttttcg gcatttttgg gatcatctgc tttttagggg
    31561 ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac
    31621 aaagtgcatc taaaaaaact tatcctaaac gtatttctat ccatcattct taaagaggtt
    31681 gtgacagaag tggtcagctt caagaaataa gaaggaaccg cttagtttcc agtcacaagg
    31741 aacaatttca aaaaacagct tctcatgttt gatgaatatt gtgacttgtg accagttggt
    31801 aggagaacac cgtttagtgg agaggtggtg aaagaaacgt tcagccttga gcgatgacaa
    31861 aagctctcac aaacattgcg acgagtaacc gtaggagcaa taagaggcgg taaaaacccg
    31921 tctcttattt ttcgttttct ttcactgttt cccgttcaac tagtacaggt tcatagagaa
    31981 tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc
    32041 ccaacttttc ttttggatgc gtcaatgttg tcaatttttt attccctaaa tggcttaaag
    32101 aagaatcgtc tgttcctacg atcgataggt catctggaat atgatagcca ttttctgtca
    32161 acttatctag cattaaacta gctatttgat cgttatagca aatgatgcca tctaaagctt
    32221 gttcttcttt caaccgttgt actgtttttt cagcgattgt ttctcgtgtt tccgtggtga
    32281 aagtaatgat atcttccgtc aaaaaacgca cattatactg ttcacacgcg ctgataaaac
    32341 ctttcatcct gtattttcct tgaagatcgt cgatttttgt gatgaacaac agacgctgat
    32401 gtcctttttt tatcaaatat tctgctgcca taaaaccgac tttcacatca tctaaacaaa
    32461 tataagaggc atttaactct tcataagcag cattgatcat caccatcgga atgccttgtt
    32521 ctctcaaagc aacataaagt gctaagtttg ggttatactg attacttttc gtaggctcaa
    32581 cgatcaaacc atctacccca taagcaatca ttttcttcaa acactctttc tccaattcgt
    32641 gatcgttatt cgtactggct aaaagcaatg aatacccaga ttctcgtaat tcattttcga
    32701 ttcctcggat aatcgacgga aaaatataat cagagagata tgtggtgatg acaccgatcg
    32761 tttttgttct gttcaatggt gttttttctt tcttatagct gtcatctaca tatgtgcccg
    32821 accctttttc tttacgcaga tagccctcat ttaccaacac agcgattgct tgccgaatcg
    32881 tatgtctgct gacgtcatat atttcttgca gcttgaattc tgagggaatg gttgtattta
    32941 cttcgtattc ctcacgaagg atcttttgtt ttatctcttc tgcaatatct tgatattttg
    33001 ccatttgcct tgcccctttt tatttgtacg tacatatatc ataacgagtc tgcaaggttt
    33061 attcaagcaa aaatcaaggt ttcttgtgct cataaggcat acggaacagg ttcaccaaat
    33121 tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg
    33181 tctaacggat cccctttttg gttcttctct ggtcgagcat gatagatcaa aatatcaaag
    33241 cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac caaattgctt atttttttca
    33301 gaagaaacga atactggctc cgataattta tgccatgatt cttttaataa aagattcttg
    33361 tgctcatcag cccacagcag gcccatggca tagttttcat ctgttgcact accagaatac
    33421 gtaatgaata ttttcccatt gcgagtaagg actgctggac cttcatttac tgaaaaaccc
    33481 cgtttttccc attcatactc aggtatagaa aggaggatct gcttcccctt taacgtccaa
    33541 ggattatcca tttcggatag ataaagatta gaattcccag taatttcagg atcttgttgg
    33601 gcccacacat aatatagctt tccttgagaa gagaaagttg ttccgtctaa actgaaagtt
    33661 tcccttttcg tttttatttg tcccttttct atccaatctg tattcattgg atctatatgc
    33721 tgattttcaa gtacgaacat gcggtgatga tgagattcat cacgtatagt tttatgattg
    33781 cttgcagcaa agtaaatata ccattttcca ttgatataat ggacttcagg tgcccagatc
    33841 aattcactca tcggtccttc ttcatgagcc tgccatacaa tcaggcttgc agcatgttct
    33901 aattcattca gtgactttgc ccttcttaat tcaatcactt ggtagcctgg aaccgatcct
    33961 gtaaaataat aataaccatc tgtatgttta tatacccaag gatctgcccg ttgccgaacg
    34021 ataggattat tataaagtgt cttcatcata acaaatttcc tcacattttc tttattctaa
    34081 ttacattcca agagtatttt tctatcccta catttaattc gtcatgtttt tctattgaaa
    34141 aatagtttat ttcaggtttt attttttctg gttcttcacg tgtatttttg tccaacagat
    34201 cgctactggt taatgtgtag tgctctcctt gatctagcaa attgaaatca tgttcaatcg
    34261 ttatcttttg ttgttcattt gtgcgattga tcaagaaaat agtcagctga ttgccgttat
    34321 ctacgatcac actgtccaca taaggaacat tttttatctt ttcacaatca taaacagggc
    34381 aaatgatttg ttgtttcaat acttgacctt tagcatattt cgataagtgt tgcatcacat
    34441 aataagttgg attcctccat gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt
    34501 ttactaacaa tgattgacaa ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc
    34561 ctaatgaacc aaataataat gtatcttcca tagtaaagta acaccaatcg atgggactac
    34621 cgacttcaaa atccctatgt cttttttccg gttgggcatg tacattccat tcatcaaacg
    34681 ctagatacat tgttttctca cttctcaaat atccttttac ataatcacaa gtagcaacga
    34741 tttcttcaat ttgacgatcg aatcgataag cttttgcaag gtatgtcgct gtatcatcac
    34801 gctcattttt aggaggttta gtcaagtctt cttcatcata cttatcaata tagttatgca
    34861 aagctaaata atctacattc tcataagctt cttctaatgc gatacgatcc cattcagggt
    34921 acgatggtaa acgtggcgta gagcttccaa ctaagattgt ttcaattgaa tcatccacta
    34981 acttcatgac ttttgaggct tcatttgcta acctaccata ttcataagca ctcttagccc
    35041 ccacttgcca tggaccgtct agctcattcc ctaaacacca taatttaacg ccaaaaggct
    35101 ttttttgccc attttttatt cttaaatcac tccagaaggt tccttttgga aaattacaat
    35161 attctactaa attttttgct tcatcaattc cttttgttcc taaattcacc gtgaatatcg
    35221 gtttcgcttg tacatgactg atccatttaa aaaattcgtg gagtccaaaa gaatttggtt
    35281 ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg ttctttccta cctacagtat
    35341 ccacccaatc ataaccagat gtaaagtttc ctccaggata gcgaatgaca cctaattcta
    35401 attcctttac ataagagagg acatcttgtc taaacccgtc accatcagct gtttcatggc
    35461 ccggttcata aatccctgta tagacgacac ttcccatatg ctcaacaaat gagccaaaca
    35521 gccgagaact gatctctcct accgtaaaat cctctctgat ttttactttc acttcttcgt
    35581 ccaacagctt tccctacctt tcatttccta tagtcaagat aatagataca agtttccata
    35641 cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa tatgagcagt acaaatccta
    35701 ataacaatac gcaacaaaga atatttctca aaaaatcaaa aaatactttc catgcacttt
    35761 gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga aatcacatat atccaggata
    35821 aaagaaacat ggaataaata agtaaaacta catatccact aattgaaagt acgattgtct
    35881 gttcttctaa taattgatta acaagaaaat aaataatgat cgttaacaga ctaaggaaca
    35941 agttcttacc aaaatgttgc tttattcctt gaaagaaaaa ataaatgata tttcctgatc
    36001 cctcaccttt ccattgcgcc attacataaa aaacagcaca tgtagcaggc acgatagtaa
    36061 taacaggcaa acacacgatt acccagagaa tacctaataa gatgtaatca gaaaccacaa
    36121 tcaactgtcc ataaaattta gtctcaacta ttttcatctt cctcactctt tcattccaga
    36181 catagctgtt ccttgaacaa aatatttctg tgcaaaaata taaaccacta gtaatggcag
    36241 cattgaaata accgttccag ccattacagg tccataaaaa gaaatgttct gccctgtaaa
    36301 taaagctaac cctgctggta aagttctcat ttttgaacta cttgtcaata tcaatggata
    36361 aagcaagtca ttccaactat tcatcagcgt gaaaatccct aatgataaaa gagtaggttt
    36421 gctcaatggc aacatgattt tcaaaaaaat attaaactca cttaatccat caatgcgtgc
    36481 tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa
    36541 tgcagttgtc atacgaggaa tgatcaaacc tgcataagta tcaagcatgc caagcaaatt
    36601 gacttcaata aatagaggaa tcatgaagac ttggaatggg atcatcattg tcagcaaaac
    36661 gaaatagaac aaaactgatt ttcctttgaa acgcatacga gcaaatgcat accccgcaag
    36721 agaatcaaag aatacagaag tgatcactgt ccctccagca aaaatcactg tatttttgat
    36781 gtaatctaat aaagggatcg ttgtccaaac cttaatatag ttatctaggg tatagctatc
    36841 tgcaaatatt ctaggcggaa atgagataat gtctttttcg tgtttaaaag aagaaataat
    36901 cagccacaaa aaaggaaacg caataaccaa caatataact agcatactaa tcgttcgaat
    36961 gattttttta ccactaactg cttttcgact attcacagta actgtaatcg agctttctgg
    37021 tgccatacag gtttccctcc tatttcattt gtttttcttt ccgtgacatg tacacattag
    37081 tggagatagc tatagttgca acaatgataa acaaaaccga agacagtgct gatgcatagc
    37141 ccaattcata aggtgctgta aatcctcgac tgtaaatata ttgaacagct gtttctgtct
    37201 taaattgtgg gccaccagcg gttgcaacat atacttggtc aaacacttgc atcgaaccaa
    37261 tcagattcgt taaaatacaa aaacctaagg agggaacgat ctgaggtagc gtaatgttaa
    37321 aaaactgctg tcgatttgtt gcaccatcca tttgagcaga ttcatacaaa gagggagaga
    37381 ttccctgaat agcagtcaag agaatcgtca tagtaacacc aaaattcttc caaacagtca
    37441 tgatggctac cgtcggcata gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc
    37501 cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa
    37561 taatcgcaat tgacgtcaat gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac
    37621 gattgaatct ggtattttta gataatgcta ctgctgctaa taaaccaacg ataatttgtg
    37681 ttggcgtttc gagtacggtg aaatataaag aatgaatcaa cgaattaact gctcgttcat
    37741 cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat
    37801 tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg tatgacagta aataataata
    37861 aaactaaaaa agatggagtt aaaaacaaat acgcagcacg atcaggacga ttccaatatt
    37921 tggtgaatcc gttcatatag tccacctcat ctttcatttt gataaaatat acaatcttgg
    37981 tttaaacgaa tctgaataag atatccgaac aatcgctgtg atttttgcaa taacacctat
    38041 ctgcaaatac taggtcgatc attcagatat ctgtatcttg ccaacagtct atcctgtata
    38101 aagttctgta ctatttttgc agtaattgat tgatggcatc atctgcatcg ttcatgagtg
    38161 tctcaggatc ttctcctgct aataattttt caatcagtgg attgatgata tcgttattga
    38221 tcgcagagat ttgggtaaaa cctggtaaat atggctctgc atagtccatt tgtttcgata
    38281 attcagatac aataggatca ttttttactt cttcatcttt tgctactgaa tccaagtagg
    38341 caggaaaacc attttcgata ctccattttt taccaatttc agttgtattc caatatttca
    38401 aaaactcata gacagcttct tttttattat tatctgtact tgccggaatg gcatatccta
    38461 cgccatctaa aatagctgtt tttttgtctg aatcactccc ttgtggtaag gtagtcacat
    38521 tataatcaat ctcgtttgct ttcaatccgt tatttaacca tggcccattg atttcaatgg
    38581 ctagttgacc agcattcatt aaattgtcca tttcggcgcc agaaatcgat tctggaccag
    38641 tcttgtctac atggatcatt ttttggatcg cttttaacgt tttaaggttc tcaggagacg
    38701 caaattcaga cttagtataa tcatcgttca ctaatttacc gccatttgct aacatccagt
    38761 tatataacgg tgcagttcca tccttattga agacaaaacc tgatacattt ttactactat
    38821 cagttaattt tggtgccatt tctgtcaatt cttcccaagt agtaggtggt tgttcagtat
    38881 ctaatccagc ttgtttaaac aaatcattat tccaatacat atacatgcct tgtacctgca
    38941 tggggacaaa atactgttta ccttctactt cacctaattc aatagccgtt tctttaaaat
    39001 cagatttatc tactccatca tattcccaga aatcgtctaa tggttgtacc gctccgtttt
    39061 ctacatactg tgcaaaatct ggataattta atgcaataaa gtcaggtgct tttttagaag
    39121 aaatcgctgt aggaagtttt tcattcaaat tggcccaagt catgatatcc atttcaattt
    39181 tgatgttttt atcatttgtt ttattaaatt cattaacgat ttcttgcaat atttcaccat
    39241 cagatgcagt aaacccattc caaaaagtca aagtcacttc tttatcagaa tcagattctg
    39301 ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc agctaccaac aaagagccaa
    39361 ttaaccattt tttacctttc attttttgtt cctccttcat ctgataaacg acatctgacc
    39421 acattccaag atagcggttt caataaacaa ttgattttcc catcttcagc ttttacattt
    39481 gttgaatgac ttggttttac ttgttcactt ttaggaagat tagttgcttt tgtatcaaat
    39541 ccactcattt cagaaaaatc aatcactccc tctaatgata attcagacaa gtgaacagtt
    39601 agattcattt cttcttctcc acggttaact gcaaatatga caagttcttt gtcatttatt
    39661 acggctatac tttctaaata cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa
    39721 cgaatttgtg ggcttaacac ctctccttgt ccatacacag cagcttgcat aaatggataa
    39781 tagatcgtct gtctccaagc ttctccgttt gtttctgtcc tgattggtgc aataacgttt
    39841 accaattgag caagacaagc aatctttact ctatctgcat gtttcaataa agtgattaat
    39901 agacagccta atagtaatgc atcttcaaaa ttatagttat cttctagtaa aggaggagca
    39961 atctgccaag gcgctgcttg ctcatcttgt tccgctgaat gataccaaat attccattca
    40021 tcaaaggaca ggttgatctg cttcttacta tgtttcttcg ccttgactgt atcgcacatc
    40081 gctgtcactt cagaaatgaa ccgatccatg tctaaggaac gtgcaagata atgagaaaga
    40141 tcattttttt ggttgccata atattgatgc agagacaaat aatctatttg atcgtacgct
    40201 tgatcaagaa ctgttaactc ccaatcacca aatgtaggca tttgccgatt cgaacttccg
    40261 cataaaacca cctcaattga atcatctacg agtttcatcg ccttagccgt ttcctctgct
    40321 aaccgtccat attcttccgc tgttttatgt ccaatctgcc aaggaccgtc catttcattc
    40381 cctaaacacc atgtcttaat tccaaaaggg ctctcttgac cattcgaacg ccttaaatca
    40441 ctccaataag ttcctttagg aaaattacaa tattcgacta aattacgagc tgcatctact
    40501 ccacgagtac ccagattgac agccatattg atttcggccc ccacatgctg acaccagtta
    40561 taaaattcat gaatcccaac ttcattcgtt tcaattgtcc gccaagctaa atccaacctt
    40621 ctaggtctat ttgctatggg cccaatactg tcttcccaac gaaatcctga cacaaaattt
    40681 ccaccaggat atctaatcat gggaatgttc aattctttta ccaagtgaat gacgtcttgg
    40741 cgaaatccac ttttattagc tgatggatga tctggctgat aaatcccttc atatactgct
    40801 cgtcccatat gttcaataaa tgaactgtac aaccgcggat caactttgcc tacacgcttg
    40861 acactactaa tcaacattgt ggcttccata actgacctcc tttaatttat acatgaataa
    40921 tacacctcgt tgaaagcgtt gtcaataata taaatgttaa acttacttat tttttatcga
    40981 ttttaattaa ccaaaatatt aataatgatt aaaacaaata atttaatata acttttatta
    41041 acaaatatgt taatatataa gaaaaacctt ttaagaggtg atatatatgc aactacaaat
    41101 aaacgaagaa tccttaccgg tatatgaagc attagctagt aaaacaagga tcaagatcat
    41161 ccagctactt tccaaaaaaa agatgaatgt caaagatttg gcaaaagaac ttggagtgag
    41221 cagtgctatc acgacgatgc acgtgaaaaa gctagaggaa gcaaacatca tcaaaacaga
    41281 aaaagtagga caacaaaaaa tttcgagcct tcgtgtcgat aaaatcgata ttagttttcc
    41341 agaaaaaata ttcaatgctt ttgatacgaa agaaacatcg atacctattg gtcactatac
    41401 aaattatgca attgaaccaa catgcggttt agctacgatc catgatttta tcgggaaagt
    41461 ggatgaacca cgctatttta tggatcctcg aaggatggat gcccgcattc tctggtttac
    41521 cagcggattt gtcgagtatc aggcacctaa ttttttaaat acagaggata cattggagat
    41581 gttggaagtt tctgtggaaa tttcttctga atttcctttt tcaaatgaca attggccttc
    41641 agatatcact ttcagcctaa atggtgtgga gctaggaaca tggacgagcc ctggagattt
    41701 tgctgatatc cgcggtaaat atacgcctga ttggtatcca gataatctta atcaatacgg
    41761 cttgctgaag acgatccgaa ttaccaaaca cttgacgaat atgaatggag aacccttgtc
    41821 aaacatcacg atcaacgaca tccctaaaga gcaagacact tggcatttgc gaatcgaagt
    41881 gaaagacgat gccaaacatg tggggggctg tactttattt ggtaaaggat tcggtaatta
    41941 cgatcaggat atcaaattaa aagtttacta cagctgatat ttttcttttc tattttataa
    42001 aacaaaaaca gccaatccct atgaagggac ggctgttttt gctttattgt tatttccaga
    42061 aatcatccaa aacggaaatt ggcaaatgtc gtttatgttg tgtcttgttc caccatgctt
    42121 cgattttttc ttgtgcttga gcgggaactt cttttccttc tagataatca tcaatttcat
    42181 tatatgtgac acctagtgcg acttcatctg caatcattgg tttcccatct tcaagatctg
    42241 cagtcggaat ttttgtgtat aatttttccg gtgcattcaa tgcttgaagc aattgtttcc
    42301 cttgtcgttt gtccaaacgg aataatggca aaatgtcggc tccaccatca ccaaatttcg
    42361 tgaagaatcc agtaatgttt tctgcagcat gatctgtccc taatacggct cctgctcttt
    42421 ctccagctac ggcatattgc gtaatcatac gttgacgtgc tttgatattt cctttgttaa
    42481 aatcgctgat tcccacacct gcttcgctta atacttgtac ttgtgcatca acagctggtt
    42541 tgatatttac tcgcagacta acatcgggct ggataaagtc aagagcagct tttgcatctt
    42601 cttcatctgc ttgttcacca taaggaagac gaacagcgat aaattgatag ttttcatctt
    42661 ttgtttcttc acgcatttct tccatcgtta gttgcgccaa acggcctgct aaagtagaat
    42721 cttggccgcc gctgatacct agtacaaaag ttttaagaaa cggatatttt ttcaaatatg
    42781 ctttcataaa gtcaatactt ttacgtattt cttcttttgg atcaattgtt ggtttgacac
    42841 ctaattcatt gataatttct gtctgcaggc tcatttattc tcctcctatg cttctgtatg
    42901 aagttctgct acgctttttt tcattcgttc catgatagcc attttatggt tccagcattc
    42961 agtagacaga tcgactgggt atttttgcgg attcaagtct cgtttatact cttcccatag
    43021 tgaatctaga ttttcttttg tatattcttt gatttcgttt agtgcaggta attcgtaaac
    43081 tctttttcct tcgataaaga tatcttgtaa aactgggcga gctgtaaagt ctcgaacagt
    43141 tttattgata aacgtatgca ctggatggaa catgaagata gcttcttctt ctcgagggtc
    43201 ttcatcccat aatgtcacgt agtctccttc agatttccca tcaaaatttc gagtgatgcg
    43261 ccacacttgt tttttccctg gagtagttac tttttctgca ttgcttgata acttgatcgt
    43321 atccatcatt tttccttcat catcttcgat cgatactagc ttgaatactg caccaagggc
    43381 tggctgatca taggctgtga tcaattttgt cccaacaccc catacatcaa ttttagcttt
    43441 ttgcatcttt aaattcaaaa tcgttgcttc atccaagtca ttcgaagcat agatttttgc
    43501 ttccgtaaat ccggctgcat ctaattgttc ccgaacacgc ttagatatat aggccatatc
    43561 tccactgtcg atgcgtacgc cttggaagtt gattttgtca cctaattctt tcgccacgcg
    43621 aatcgcactt ggcacacctg atttcaacgt atcataagtg tcgactaaga acacgcagtc
    43681 tttatgggtt ttagcgtagg ccataaatgc ttcataatca tttccataag attggactaa
    43741 cgaatgagca tgggtcccgc tagctggtat cccaaatatc ttcccagcac gtacattgct
    43801 tgttgcatct gctccgccga tatatgccgc tctagttccc cagactgctg catccagttc
    43861 ttgtgcccgt ctagttccaa attccaatag tggatcttct ccgatgacag atttgatacg
    43921 agctgctttt gtcgcgatca acgtttggaa attgaccata ttcaacagtg ctgtttctac
    43981 taattggcag tgcgctaaag gcccttccac ttggatcaat ggttcatttg caaaaactag
    44041 ttctccttca cgagcagaac gaactgttgc tttaaattca aaattttgta aatactccaa
    44101 aaaaccttca ggatagactt ctaatccacg caagtaagca atatcggaat cattgaacgt
    44161 cagattctct aaataattga ctaaccgttc caatcctgca aaaaccgcgt atccgtggtt
    44221 aaaaggcatt tctcgaaagt aacattcaaa aacagcatgt aaatcagctc gacctaattc
    44281 ccagtatgtc tgcatcatat tgatttgata tagatccgta tgcagcgtca aactgtcgtc
    44341 tgggtaagta ttattcatct tgtattactc ctcttggcaa gttttcattt cctacccatt
    44401 ataacaaaaa aaattaatag gaaaagaaat cttccatttt ttctgaaaaa gcacatgttt
    44461 tacggatatt tcttgctaaa aatgaactcc atctgctaaa actatccttt cttattggta
    44521 tttaacctaa acgagaaaga atacttattt tattcaatgt atccgagaca cgaagaaatt
    44581 agcgttttct atttttctta cttgataaaa taagtagatt ttcctactac aatcgtagcc
    44641 gttaagatac cgatgattga acaaatataa ccaaatgtct ctacaacata atcaatggca
    44701 aaagtttttg aagcaataat acgtctttcc ttttttgctt cttatcccca aagaaacgga
    44761 tataacttat tatgtattga atttttttgg aaaggcgaat tatgacaaga tataccttgc
    44821 gttgaaaaaa ctcgcggaaa aaatatcaca cgtttttaaa aagatacaaa gtaagaaagc
    44881 agctgtcaat agaatggaaa caaaaatggc gagacatcaa tcagtctcgc cttgtttttt
    44941 attgtataca ttagatatgg agcaggttac cataaagatg attattagtc gttattaaat
    45001 agaatccttc gtattttttt gttctatcac tacaatatct ttatttggac gtttgaattg
    45061 tattccggca cgttctagct cctgtttcac tcctacatgg actttgacat cttctcgtgt
    45121 catttttaaa acgtgatgaa tcgcatagtc gatttcttgc cttgtgattt ttttcttcgt
    45181 attgatcatc acgacttgct ttttatcata tgtgtctacc aatagcagtt gtgttcgatc
    45241 taacgaaaat aatttgtaat aattaatagc cgtattccca aaaaagaatt ccactacttt
    45301 aggataaaat gtcttaatat ttaaattact attcacaggt gtttcgatta gcttcatctc
    45361 attcctcttt tctatatagt cgatttagat ccaatcttaa gttatgttac catctttcct
    45421 agcattaagg aatcggttac aattgaacct ttaaagacaa aaggatttac cttttatcac
    45481 ttaatagtat aacataattt catgagaaaa aaatacaatt ttttcttgac catctcgtta
    45541 cgtaaaggat tatgcttaca tttgtcagga ggaaaaataa tggagtacac aataaagaaa
    45601 atgtcagaga tatcaggagt cagtccgaga accttgcgct tttatgatga gattggactg
    45661 ctaaaaccag ctaggatcaa ttcttcaggt tatcggattt atggcaaaaa agaagtcgat
    45721 cgtctgcaac acatcttatt ttatcgaaca atggcattca agttggatga tatccaagag
    45781 gtcttagaca atccatcttt tgaccaccag aaagctttaa tcaagcatca gcaaatgttg
    45841 ctggaaaaac gggcacaaat cgataccctc ttgacaactg tccaacagac acttgatatg
    45901 tacgaaggag gaagaaaaat gagtgacaaa gaaaaatttg aagggtttaa acaacaaaag
    45961 ttgaaagaaa atgaagaatc ctatggacaa gagattcgac aaaaatacgg aaaaaaaaag
    46021 gttacagcat ccaatgaaaa atggatgaat atggataaag aaacgtatga agaaatgcaa
    46081 actgttgaaa agcagatgtt atttgatctc actctttact taaaagaacc agaagatgaa
    46141 agcttagcag accgtatctt ccaagctcat aagaagtggt tatcttacag ctggcctgaa
    46201 tatcagccaa aagcgcataa aggactagga atgatgtacg aagccgatga acggttcact
    46261 gcatattatg acgagcgaag tggtcatggt gcagcaaaag ctttaaatga aattatccaa
    46321 aaaaaggcgt aatcttttac atgatccaac aaaaaagtac acgtaaaatg acctaataac
    46381 aaaacagcag acacccaagt tagattttta tgctaacttt tggtgtctgc tccattcttt
    46441 cacaagtttt ttcatcctac tttaaatata ttcatcgttg aataaacgta taaggtattt
    46501 tcactttatc ctttttttct gtaagaaaca attgaaatgc catttctccg caagcttcca
    46561 gatggtggtc gatggttggg aaaccaagaa gctcgctgat cagcaaatta tcgcgtccaa
    46621 tcaccactgg tgtcttatct tgcagatagc tttgcaagat gcctgctgca accatatccg
    46681 aatttgtaaa gacaccatca actccaagct ctttaaaaaa gaagcctgct tgttttcctt
    46741 tctctgcatc tatacaatcc caaaaaacaa gtgattcatc aaaagatgga aaaagttgat
    46801 gacatagctg caaagtgatt tttgagttat aacttagcct gccacttcgc cccaacgtga
    46861 tgcccaattg ctttatacct tgctgcttca aataagtaag accttctgta attgattgtt
    46921 ctcgatcaat aaagacacag cttgcctgtt ttcccttgat ttcttcacaa aaaactagag
    46981 gtccatattt ttgatatgcc aataaatcat ctagtgtatt ggcacgagac gtaatgatca
    47041 atccatcgaa agctttagct gcaaattctt caagatacct tcgctctttt tctttctgat
    47101 agcccgtcgg taaaagtgtc actttgtaat cataatcaaa cgctgcttca atgatcccac
    47161 tgatcaactg atcaaaatac ggatgattgg tataaggcag aatcactcca atgcttttcg
    47221 tttttccata acttaactgt ctggcatttg cattagggat ataatcgact tctttcatga
    47281 ccgcaagtat ttctttcctt ttttcctcat ctacatatgg atgtccattg attacacgtg
    47341 aaatagtaga aactgaataa cctgtgagct ttgcgatatc tcgaatgttt gccactgctg
    47401 cttcgccacc tatacaaaaa gattttcttg taaatagtct accacagctg gaccgcattc
    47461 aaaaaactga tacatttttc cttcatgcga aaaactgatc cgctgcccgc cccaatatat
    47521 atcttttgtc aaattttcga tttcattcat tggtatttct tttactatat tcctattcaa
    47581 cccttgaaaa ctgtacaacg ttaatacgga tcccttgaac tcgacaaacg cataaaaata
    47641 attgttcgtt gtgccatctg ttatctctac ataagtattc attgcaagcc ctccttttga
    47701 tactttgagt atagtgtatg aaacgcgtct catagcaagg agtttgtttt gccaaagaaa
    47761 agttttattc ctctttcatt attaccaaag tctcttattt taaattgaat acattataat
    47821 gatactgtaa atatatcttt attattagtg aatggatatt tacttttaat agataaaaaa
    47881 ttataactat taaaaataac tattttcatt ataatta
//
LOCUS       DAXLPY010000015        47471 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.015, whole genome shotgun sequence.
ACCESSION   DAXLPY010000015 DAXLPY010000000
VERSION     DAXLPY010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.015"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(56..790)
                     /locus_tag="ACF3UF_000940"
     CDS             complement(56..790)
                     /locus_tag="ACF3UF_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFD3671087.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1117..1527
                     /locus_tag="ACF3UF_000941"
     CDS             1117..1527
                     /locus_tag="ACF3UF_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFD3671088.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1520..2221
                     /locus_tag="ACF3UF_000942"
     CDS             1520..2221
                     /locus_tag="ACF3UF_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFD3671089.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2221..3807
                     /locus_tag="ACF3UF_000943"
     CDS             2221..3807
                     /locus_tag="ACF3UF_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3671090.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3826..4047
                     /locus_tag="ACF3UF_000944"
     CDS             3826..4047
                     /locus_tag="ACF3UF_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFD3671091.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4044..4805
                     /locus_tag="ACF3UF_000945"
     CDS             4044..4805
                     /locus_tag="ACF3UF_000945"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFD3671092.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5185..5694
                     /locus_tag="ACF3UF_000946"
     CDS             5185..5694
                     /locus_tag="ACF3UF_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFD3671093.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5769..6308)
                     /locus_tag="ACF3UF_000947"
     CDS             complement(5769..6308)
                     /locus_tag="ACF3UF_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFD3671094.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6448..7059)
                     /gene="rpsD"
                     /locus_tag="ACF3UF_000948"
     CDS             complement(6448..7059)
                     /gene="rpsD"
                     /locus_tag="ACF3UF_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFD3671095.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7321..8172
                     /locus_tag="ACF3UF_000949"
     CDS             7321..8172
                     /locus_tag="ACF3UF_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFD3671096.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8200..8835
                     /locus_tag="ACF3UF_000950"
     CDS             8200..8835
                     /locus_tag="ACF3UF_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFD3671097.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8855..9628
                     /locus_tag="ACF3UF_000951"
     CDS             8855..9628
                     /locus_tag="ACF3UF_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3671098.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10036..10833
                     /locus_tag="ACF3UF_000952"
     CDS             10036..10833
                     /locus_tag="ACF3UF_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFD3671099.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10811..11224
                     /locus_tag="ACF3UF_000953"
     CDS             10811..11224
                     /locus_tag="ACF3UF_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFD3671100.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11208..13853
                     /gene="mutS"
                     /locus_tag="ACF3UF_000954"
     CDS             11208..13853
                     /gene="mutS"
                     /locus_tag="ACF3UF_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFD3671101.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13871..15979
                     /gene="mutL"
                     /locus_tag="ACF3UF_000955"
     CDS             13871..15979
                     /gene="mutL"
                     /locus_tag="ACF3UF_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFD3671102.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16001..16561
                     /locus_tag="ACF3UF_000956"
     CDS             16001..16561
                     /locus_tag="ACF3UF_000956"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFD3671103.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16646..18634)
                     /gene="treP"
                     /locus_tag="ACF3UF_000957"
     CDS             complement(16646..18634)
                     /gene="treP"
                     /locus_tag="ACF3UF_000957"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFD3671104.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18857..19570
                     /gene="treR"
                     /locus_tag="ACF3UF_000958"
     CDS             18857..19570
                     /gene="treR"
                     /locus_tag="ACF3UF_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFD3671105.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19647..20093
                     /gene="msrB"
                     /locus_tag="ACF3UF_000959"
     CDS             19647..20093
                     /gene="msrB"
                     /locus_tag="ACF3UF_000959"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFD3671106.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20263..20865
                     /gene="ruvA"
                     /locus_tag="ACF3UF_000960"
     CDS             20263..20865
                     /gene="ruvA"
                     /locus_tag="ACF3UF_000960"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFD3671107.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20878..21879
                     /gene="ruvB"
                     /locus_tag="ACF3UF_000961"
     CDS             20878..21879
                     /gene="ruvB"
                     /locus_tag="ACF3UF_000961"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFD3671108.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21908..22486
                     /locus_tag="ACF3UF_000962"
     CDS             21908..22486
                     /locus_tag="ACF3UF_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3671109.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22538..23020
                     /locus_tag="ACF3UF_000963"
     CDS             22538..23020
                     /locus_tag="ACF3UF_000963"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFD3671110.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23137..23511
                     /locus_tag="ACF3UF_000964"
     CDS             23137..23511
                     /locus_tag="ACF3UF_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671111.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24189..25541)
                     /gene="brnQ"
                     /locus_tag="ACF3UF_000965"
     CDS             complement(24189..25541)
                     /gene="brnQ"
                     /locus_tag="ACF3UF_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFD3671112.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25688..26278
                     /locus_tag="ACF3UF_000966"
     CDS             25688..26278
                     /locus_tag="ACF3UF_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFD3671113.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26406..27755)
                     /locus_tag="ACF3UF_000967"
     CDS             complement(26406..27755)
                     /locus_tag="ACF3UF_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3671114.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27923..28663)
                     /locus_tag="ACF3UF_000968"
     CDS             complement(27923..28663)
                     /locus_tag="ACF3UF_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3671115.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28676..30268)
                     /locus_tag="ACF3UF_000969"
     CDS             complement(28676..30268)
                     /locus_tag="ACF3UF_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFD3671116.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     regulatory      complement(30406..30580)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(30836..31132)
                     /locus_tag="ACF3UF_000970"
     CDS             complement(30836..31132)
                     /locus_tag="ACF3UF_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671117.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31308..32033
                     /locus_tag="ACF3UF_000971"
     CDS             31308..32033
                     /locus_tag="ACF3UF_000971"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFD3671118.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32026..32868
                     /locus_tag="ACF3UF_000972"
     CDS             32026..32868
                     /locus_tag="ACF3UF_000972"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFD3671119.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32871..33392
                     /locus_tag="ACF3UF_000973"
     CDS             32871..33392
                     /locus_tag="ACF3UF_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFD3671120.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33645..34208)
                     /gene="def"
                     /locus_tag="ACF3UF_000974"
     CDS             complement(33645..34208)
                     /gene="def"
                     /locus_tag="ACF3UF_000974"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFD3671121.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34459..34728
                     /gene="rpsO"
                     /locus_tag="ACF3UF_000975"
     CDS             34459..34728
                     /gene="rpsO"
                     /locus_tag="ACF3UF_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFD3671122.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34916..37042
                     /gene="pnp"
                     /locus_tag="ACF3UF_000976"
     CDS             34916..37042
                     /gene="pnp"
                     /locus_tag="ACF3UF_000976"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFD3671123.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37552..37818
                     /locus_tag="ACF3UF_000977"
     CDS             37552..37818
                     /locus_tag="ACF3UF_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3671124.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37962..39953
                     /locus_tag="ACF3UF_000978"
     CDS             37962..39953
                     /locus_tag="ACF3UF_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFD3671125.1"
                     /translation="MATTHNTKKISMTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40307..41608
                     /locus_tag="ACF3UF_000979"
     CDS             40307..41608
                     /locus_tag="ACF3UF_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFD3671126.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41738..43108)
                     /locus_tag="ACF3UF_000980"
     CDS             complement(41738..43108)
                     /locus_tag="ACF3UF_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFD3671127.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVNPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43290..43613)
                     /locus_tag="ACF3UF_000981"
     CDS             complement(43290..43613)
                     /locus_tag="ACF3UF_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFD3671128.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43938..44546)
                     /locus_tag="ACF3UF_000982"
     CDS             complement(43938..44546)
                     /locus_tag="ACF3UF_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFD3671129.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44876..45592
                     /locus_tag="ACF3UF_000983"
     CDS             44876..45592
                     /locus_tag="ACF3UF_000983"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFD3671130.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45605..46300
                     /locus_tag="ACF3UF_000984"
     CDS             45605..46300
                     /locus_tag="ACF3UF_000984"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFD3671131.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46384..47013
                     /gene="udk"
                     /locus_tag="ACF3UF_000985"
     CDS             46384..47013
                     /gene="udk"
                     /locus_tag="ACF3UF_000985"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFD3671132.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15392 a         8788 c         9878 g        13413 t
ORIGIN      
        1 aataaaaaaa cttggtacgc aatcgctgta ccaagttttt ttatttagct tttgattaag
       61 ccataaataa taatttatat aagaatactg ctacgacacc agcacagata ggtgctacaa
      121 ctggtaccca tgcatatccc cattgagaag aacctttatg tttcaatgga agaagtgcgt
      181 gtacaagacg tggagcaaag tcgcgggctg ggtttagtcc aggacctgta ggaccaccaa
      241 gtgaagcaac taatgtccat acaaggaaac caagtgctaa gtgagctgta ccaagattat
      301 cttggaagaa tggtgctttt gtaataccta gggcaccaaa gaataaaacg aatgaaccaa
      361 agaattcatt gacgaaacca ttgaatttag aaccaacgct gttgattgtt gagaatgtac
      421 ctaacacatg gtttacgtct tctgtttggt cgtagtaagg tttgtaacaa gctactacga
      481 tcaattgtcc aatcgctgca ccaatcaatt gtgcaatgat ataaggaaca acttcagccc
      541 aagggaatag accattagat gctaaagcaa ttgtaaatgc tgggttgatg tggttaccgc
      601 tgattccacc aaaaatcatt gctggcatca taaccccgaa tccatacccg acagcaatca
      661 gcatccagtc actgccatat ccttttgtac cttttaaatc tacgtttgct acagcaccgt
      721 tacctagaac gattagtaat gctgtaccaa tcatttccgc cgcaagacgg gtcattagtg
      781 agtaatccat aaatacctcc aaaagttata aaaatgcaaa aaaaaaagaa acatcaacac
      841 gaaaagcatc ggtgcagtgt ttcgtgtcgg aaggatttct gcagtcttaa caaatgtgaa
      901 taaaaaaatg aattccatta cttataagaa accagaccaa cagtaaaact ccaactcttt
      961 ttaaaagttc tccacaaatc accaagctta actataaata taccaaaaaa aaaacgtttt
     1021 ttttctcaaa aattgtatct tagaaacagc atgttttgaa actttcagaa aaggtttgtt
     1081 agtaaaatga aagctatacg taaggagtgt tgtttgatga aattttttca agagtttttc
     1141 attattattt tcttttctgt attaggagaa ggcatacgga tttttgctca tttacctatt
     1201 cctggaagta tcttaggtat tcttttttta tttttagcat ttgaaatgca tcttgttgat
     1261 cctgaaaaaa tcggagcaac tggtgatttt ttattgaata atctagccat tttatttgtt
     1321 cctgctggtg taggtttatt ggaatatttt gatgatattg cttcgatatg gcctgtttta
     1381 ctgggagcag tcgtcgtgtg ttccatcgtc acgatggttg cagcgggaaa aacggcagaa
     1441 ggtgtagaag ctttgctggg ctatgtccgt aagaaaaaag cagaaagggt atctgtaaac
     1501 gaaatggagg agaatcaaat tgactgagtt ttttgtgaat ccattatttg gcttaagttt
     1561 gactttagga gtgtacgtat tatctgacaa atttttgcgg aaatataaac tgcctgtttt
     1621 gaatcctctc gtattatcga ttgttgttat tatcttattt ttgcattttt ctgggatcag
     1681 ctataaagac tataatatcg ggggcaattt tttgactatg ctgattactc ctgcgacagt
     1741 ggcacttgcc atccctcttt ataaaaactt ccgtttactg aaagagaatt tttatcctgt
     1801 aatggctgcg attttagcag gaatagtcgc aaattgcttg gttagtgtag ggttcggtta
     1861 cttcttctct cttcataaag agatggtgat ctcattacta cctaaatctg taacgacggc
     1921 tatttctgtc gatttatctc atacgatggg cggggtgaat gccgtgacac ttgctattgt
     1981 tgtctctaca ggtatttttg gttcgctgat cgccactcat attttccgcc tattcaagat
     2041 cgaaagtcca gttgctcgcg gtgtggcgtt aggaagtact tctcatgcta ttggtacagc
     2101 aaaagcaatc gagattggtg aaatagaagg aatcatttcc ggacttgcga tatgcgtcaa
     2161 cggaatattg accgttttat tgctaccgtt attctttcag ccttttgctg gcttgttttg
     2221 atgcgaaaac cactatttta tgctacaata accaaaacgt tcgagcataa aaaaggaggg
     2281 aaagacgtgt atttgtcttc cgagtatctt aaacaatttg ataaagatct atattataag
     2341 attctcctcc tagaaagttt tgaggatcaa gcttggcata ccgctgcaca attagcgcaa
     2401 gttgttcagc tggatgcccg cagcgtgtcg aaatacctga acgagctgtc taaaaactat
     2461 cagcagttta gcggtaagac acaccctttg tttacaaaaa atcaccgttc tggttataac
     2521 ttttatgata cgctcgattc aattgaacat gagcgttttt tgatctatct cgtgcaaagt
     2581 acgctgaaat tccagttgct gcacgacatt ttttttgaag aattccatac aatgtaccaa
     2641 tttgcgcaaa agcattacat tagtgaatct actgctcatc gaaaaatcaa tgaatggaaa
     2701 cagcaactgc aaacttacgg aattcggctg caacgaggta catatatcgc tcaaggcgaa
     2761 gaagaaatca ttcgacttta cttgcatatg acattctggc agttgtttcg agggaaaatc
     2821 tggccatttg aaacgatttc tcaaatggac gtaaagaata tggcagaaca tatcatggct
     2881 ttttttaatg ttcgtctgaa cgagatcaaa aaaagacgat tggaatatat gctaggtgcc
     2941 ttttttttaa gaaaatcaca gaagcattat gttgtattga atgagaaaaa aagacggctg
     3001 atttctgaca atctgttgtt ccagcgattt tgccaggtca tggagccggt atttcctaat
     3061 tattttcaag tagaagacga gttaggcgca ttatttcttg tactgatgac tcgtgaagaa
     3121 tattatagtg atcctaagat acggaagaaa atttttgatt ttcatcaaca agcaaaaaca
     3181 ccgcccttta cagccctttc agaagcaaaa gccgctcttt ctctttatca ggaagagcag
     3241 gggctgccag cagaaaatct aaccttcgag gcagaaaact atttattcag cagtcatttt
     3301 ttcgcctatc tttttcctaa tgcgaaagaa acgattgatg gcaatagtag tgattttatt
     3361 aatcatttag ttattgaaaa caaggaattg aaacaatggc tcgtacattt ttttgaaagt
     3421 agacacaaac atcccaatca tctggcattt aaaaatcatg cgtttttgat ggggcggtat
     3481 ctgactgtgt ttaaaacatt aggagccttt actccacagc ttccaaagat cacgatcctt
     3541 ttaatgacag atttcccatt atttgaagag caactgttag aggagggatt acggacattt
     3601 ttccgtaatg agtatcagct gatttttctg ccaacagatt atcgggggag agaagttgat
     3661 cttctgattt cgacaagtaa agtccaccgc aaaccatggg cggatcttga ctattttatt
     3721 gtgactgaag aactaaaatt aattgattac atccaactat ctcaaaaatt tgaaatgatt
     3781 caaaaacaaa aactattaaa acaataacaa agaaggagaa aaaagatgac atttgaagaa
     3841 attttaccag aattgaaaaa aggtgcaaag attattcgta aaggatggag tggatttgaa
     3901 ctttatgttg ttctcgtatc cgatgatgaa tttgatggct gtccggtgac gccgtactta
     3961 ttgatcaaaa caagtgacga aggtttttcc agcttcgctc ctacagtttg tgatatttta
     4021 gcagatgatt gggcgatcgt agaatgaaaa accagtatcc agatctagct aaacaggttg
     4081 tatttatcac aggagctgct tctggaattg gtgctgcgca agcccgagcg tttcttgaac
     4141 aagatgcttt tgtatttgga ttagatcaaa agttcggtaa aatggaagaa atttctttgc
     4201 gatttcctga aacttttgcc tacgcactag gtgatgttcg acaaatgaaa gaactccaac
     4261 aagcggtatc gaaatgccaa aatcattttg gtgaagttac gattttactg aatacagcgg
     4321 ggatattgga tgcctacaaa cccttgatgg aaactgacga atcgctgtgg gatctgattt
     4381 atgagacgaa tgtgaaaagc atgtatcagc tgacaaaaat catccttcct gatatgatcc
     4441 gccaaaaaag cggaacgatc atcaatatgg cttcgattgc tggcttgatt gctggtggag
     4501 gtgggatcgc ttatacaagc gcgaaacatg cgattgtcgg atttaccaaa caactcgctc
     4561 tggattacgc aggacagggt atccgagtaa aaggaattgc tccaggagcc atccaaacac
     4621 caatgaatgc ggctgatttt gaagggaaag gtgagatggc agagtgggtg gcaaatgaaa
     4681 caccagtcaa gcgatgggca cagccggaag aagtagctga gctgacgtta tttcttgcct
     4741 ctcctcaagc aagctacata caaggaacga tcatcccaat cgacggcgga tggttgttaa
     4801 aataaccttg tgtttttttc aagcttctgt atgataaaac taaagagaga aacaacggtt
     4861 gatgataaaa aaagtcgatg actgttcccg acattcgatg ccgaacagcc agttcaaaaa
     4921 attcttttta ataatcgtta atattcgaaa ctaagcggct tttcacgacc tcttgatata
     4981 aacgatattc aaaagcttgc aactgcggta acaagtccag ccaaatgaaa aatataagga
     5041 gctattttta tttgaccatt cttattactt gttgcagggc agctttttca ctaccttctg
     5101 cgacacttca gttggaattt tcttcccatc ctttggtcgc ggtcattacc aagataaaat
     5161 tatcttgcaa aggagaaata gaacatggaa aaaaataata cccgttcagc caaacgctgg
     5221 acaacgacag atgtgactcg gatggcgcta gtcactggtt tatatgtggc agtgacgctg
     5281 gttttgtctg tctttagctt tggagtgatt cagattcgtc tctcggagat gttcaactat
     5341 ctgtccttgt ataacaaaag atacatcgtc gcggtaacag cgggagtagc tttggctaat
     5401 attgcttctc ctcttggact gatagatgtt gcagtaggaa gcgtcagcac gctgcttgta
     5461 ttgcttatca actataaaat cactagtcgc atcaaaaaca tgaaaatcaa aatggccgtg
     5521 acagcatgcg tatttgcttt ttccatgttt acagtagctg gtcagctaac gattttatat
     5581 caactacctt ttttcttgaa ttggtgggtg attgctttag gagaattggc atcaatgatt
     5641 gtcggtggga taattattta ttggatcggt aaaaaagtgg atttgtcaaa ataaagatct
     5701 gtttaattta aaatagggca gcatggaaga gactgaatgt tgagtcttct tccatgctgc
     5761 ttttttgatt aatttgtatg aagaaatcga tttagccgtt ttttcatcaa gataccgata
     5821 taagctgctc cagttgcctt gattgcttcc ggcagtaaaa acggcagtag tccactggca
     5881 aatgcagttg taaaagtaag atcaccactt attttcagcc agatcgttcc gcagatcaat
     5941 gcagcaagag agcccattag attggcaaag attgcatata agtaatgagc atccgttctt
     6001 tcgatcatcc aaccagttat ccacgtttgt aagagaaatc caatcaaata tccgccagtt
     6061 ggcccaaata aaacagctat acctccagtc atccctgaaa atacaggaag accaatcaag
     6121 ccaagtaaaa gataaactcc aacagatatc aatcctagtt ttcttccgag aaaagttgct
     6181 gttaatccaa tagcaaatgt ttgccctgtc aaaggaacca aaccaaaagg aatggtcatc
     6241 tgagaaagga cagaaataat cgcggcaaat tccgcagcaa gtatcaattc tttcaatgtt
     6301 cggttcataa cgccctcttt tcgttaactt aatattttta tttggttaac gaaattgtaa
     6361 aacaaagtga ttactttgta aatagaaaat ataaaaaaag accagctatc caatagatag
     6421 cggtcttttt caagaaagct tttgaaatta taagctttgg ttgtagtatt caacgacaag
     6481 agcttcgtcg atttctggat atagttcgtc acgttctggt aaacgagtca atgaaccttc
     6541 caatttttca gcgtcaaagc ttacgaatgc tgggcgtcca acagttgctt ctacagcttc
     6601 ttttactgtt acgatgtttt gtgatttttc acgaactgag atcacttgac ccacttctac
     6661 gtggtatgaa gggatatcaa cgcgtttgcc atcaactaaa atgtgaccat ggttaactaa
     6721 ttgacgtgct tgacgacgag tcgttgcaag tcctaaacgg taaacaacat tgtctaaacg
     6781 ttgttctagt aagatcatga agttaacacc atgtttacct tctttgattt tgctagcttt
     6841 tacgaacaag ttacggaatt gacgttcgtt cattccgtac atgtgacgaa gtttttgttt
     6901 ttcagttaat tgcatgccgt attctgattg tttgccacgg ctattaggtc catgttgacc
     6961 tggtgcgtaa gggcgacgtg ctaattcttt tcctgtgcct gacaatgaga tgcctaagcg
     7021 acgagaaatt ttccatgatg gtcctgtata acgagacatt aaaatttcct ccaatgaata
     7081 taagtttttg gagtaaaata atccgttgaa aaattcataa tcatatagtt tgttcttcaa
     7141 tcttcacctt tgcagccgcg gttacacaat cgaacccgag acggggcaac aaactaggga
     7201 tgagttatta tttttctgct gcattatttt acacaaatta cagtatatga tagatcatcc
     7261 acgaatgtca agataattag tacataaaaa cgctttacaa acctaggctg tctttataaa
     7321 atgagagggt atgtgcaaat ggaaaaaagc gaaggaagtt taaggagaaa atcaatgaat
     7381 ccggtatcac cattatttga gaaaatcgat gcttcaattg aaaagaaggc gaatcttttt
     7441 gaaaacagct tttcacgtta cgctgttcga gcggttctcg cctgtttgtt tttgacttta
     7501 ggaacggctg tggcatttgc gatcgcgatg aagggggaag atatcgcgca tggtctagga
     7561 aagattttat acgcatttat gttcagctgg ggtctggtca tgattctata catgaacgcc
     7621 gaattaggaa catcgaatat gctttatatg accgtgggtg tttttcggca gagacttgct
     7681 ttaagtaagg cagccaagat tctatttgcc tgtatttttt tcaatatgat tggcggtata
     7741 ttatgtggat ttctaatttc tatgactacg ccatttcaag atttaacgtt ggacaacttt
     7801 atgttagaat caatagcagt aaaactagca aaaccttcag caacgatttt ggtggaaggg
     7861 atgtttgcga atatcgttgt caataccgct gtactgatca gcatgcggat gaaagaggat
     7921 gtcggaaaag tgatcacagt cgtattcatc attttcattt ttgctttttt aggatatgaa
     7981 cacgtgatag cgaattttcc tgcctttacg cttacttact ttgcttctca cggacagatg
     8041 gatggaatga cagtcagcaa tgtgttacat aatttgtttt ttgctttggc aggaaattat
     8101 attggtggcg gtttagtaat gggactggga tatgcttggc tgaatcagtc aaaatcatcc
     8161 tatgtggact aaaaagtcgt tcattaaagg ggaagtgcca tggaagtttt agtttttcca
     8221 aaaaatgagg aaaaagcgtt acaaatggaa aagtacatga aaaatctttt ttcctttgct
     8281 ggagtaccta agccggaacg cgctctttta caacaaccgt tactggatga gagcaaaaat
     8341 ttatctattt ctgaagtttt agcttttgtt cattattatt atgaacaaat cgaaagagag
     8401 tatcagtatg tagcgatcga tttagtccag aaaaacatca aacggcttac atttgaagac
     8461 ttagtcgtat tgttgccact agttcagaaa aaagaatggt gggacagcat cgactcttgg
     8521 agaaaagtat acagcacatg gtgtaaagcc tacccagagc agcgtgaaga agtctttcaa
     8581 ttgtttgaaa aaaaggaaga tttttggcta cgtcgaatag caatcacgtt gcaattaggt
     8641 tataaacagc aaacagacac aggactattg atccgagcaa tagacgaaga tcgtcaaaca
     8701 aaggaattct ttatccaaaa agcaattggt tgggcattac gcgattatag taagaccgat
     8761 gccgattggg taaaaagaca gctgacaaca gatttgagta agttagctgt tcgagaggca
     8821 agtaagtatt tataagaaag cgagacgaca agagatgaga cgcaaattat ttgcttttga
     8881 tattgatgga acgttgttag attcaaacaa acaagcttta gatagcacaa gagaagcatt
     8941 ggaaaaatta cgcaaagccg gtcatctggt cacgattgct acagggcgga gccgatttca
     9001 tgcgcaagag atcattcgcg atcttgattt tacgaactac attttatgta atggagcggc
     9061 cggtttttta gaccatgaac aagtatataa gaatttacta gatcgcgacc agttggatgc
     9121 gttcgttcaa gaagcgcatc atgagcagat cgatacagct tttgtcagct tagacaatat
     9181 caagcgttct tcttccaatg atgtaacggt gatggaagaa gcgatgcatt ctttcggtgc
     9241 tgtcttgcct gaattagatc agttttttgc agaggaacaa gaaatatacc aagcgttagc
     9301 atttttcgat caaacatatg atgggaagtt ctcttcatat gataaaattc gatttgtccg
     9361 ctggcatgag aacagtgtag atgtcgtacc taaaaatggt tctaaagcag cgacaattct
     9421 gcacttagca gaacaagtag gcatccctca tgaagacatc atcagctttg gcgatggaca
     9481 aaacgaccgt gaaatgttgc gcatgtcagg aattgggata gctatgggga atgctgtgcc
     9541 agaagtacaa gcagaagcta agatggtcac tgatacaaac gatcaggatg gaatttggaa
     9601 ggcattgaaa gagttaagcg tgatttaaaa gaggttgtga aaaagctgtt ctgcatcaag
     9661 taataagccc agccaaacaa aaatagctcc tcctattttt cgtttttctg ggcttattac
     9721 cgcagatgca agctttcgaa caccgtttaa ggaagaggtc gtgacagaag tggtcagttt
     9781 caagaaataa gaagggattt acgaaaattg cttctcaaat ttttgtaaaa ttacggctta
     9841 tttctgaaga agtagatgaa acaacgttta ttcgggaaat gggactgtga caagatgttt
     9901 gtcatagtcc cattttttta ttttattttt caaaactaag aaataccagg aaagagttcc
     9961 ttttgtttga ccttttcttt cttattgaaa acaactataa tatagagtga tgttaaaaga
    10021 gaagaggaat ttagtgtgcg ggtattgttt attggtgatg tagtaggttc aatgggacga
    10081 gagatgatta ctgaatatct tcctagattg aagaagaagt accgtccgca agtaacgatt
    10141 gtaaatggtg agaatgccgc ttctggacgt ggaatcacag aaaaaatcta taaaaaattt
    10201 ttgcaagacg gcgtagatgt cgtgacgatg gggaatcata cgtgggacaa ccgcggaatc
    10261 tttgagtttg taaatgaagc taaaaagatg gttcgtccgg caaattttcc ggaagggacg
    10321 cctggacaag ggatggtctt tgtcaaagtg aaccaagtcg aactggcagt gatcaacatg
    10381 caggctcgtt cttttatggt ggacttggat gatccttttc gtaaaatgaa tgagctggta
    10441 gaagaagcca gaaaacgtac gccgatcatt tttgtagatt ttcatggaga aacaacaagt
    10501 gaaaaacaag caatgggctg gtttttagat gggaaagttt cagcagtggt cggtacacat
    10561 acacacgttc agacaaatga tgcgcgaatt ttgccaagag gaacagcgta tctgacagac
    10621 gttgggatga caggtcccta tgatggtatt ttgggtatgc gcagagaacc tgtaatcgaa
    10681 aagtttctga ctgcattacc aaaacgtttt gaagttgtgg aacaaggccg atcgatttta
    10741 agcggctgta tcttggaatt ggatgatacg acaggtcatg caaaagaaat ccagctgatt
    10801 cagatcaacg atgatcgacc gttcatggag tagaaagaga ggcagttttt tgcagcagga
    10861 gccggaaatt caaaaagaag taaggaaact gacaaaactt ttaagagaga atgaaacgat
    10921 cattcgctac aaagaacttg aagaaaagat ccagcaaaac cagtatttag ctgagttgag
    10981 agaaaaaatc aaacaagcgc aaaaagatgc tgttcatttt gcccactatg acaaaccagc
    11041 agcagaaaaa gaagcaatca aacaagcgga tcaattcatg caagaatttg atcagcatcc
    11101 gcttgttgta gcttatagaa aacagctgtt ggaagcagat gatctgcttc atcatttaac
    11161 aactatgata caagaagaaa tcaatggaca aatagaggag gaaaaacatg cctcaaaaaa
    11221 ctaaaaatac tcctatgatg gaacaatatc taagcatcaa ggcccaatac caagatgctt
    11281 ttttgttcta tcgtttagga gacttttatg aactatttta cgaagatgcg atcaaagcgt
    11341 cacagctttt ggaattaacg ttgacgagca gaaatcgaaa tgcagaagaa cctattccta
    11401 tgtgcggtgt acctcaccat gcagcacaag gatatatcga tgccttgatt gaaaaaggct
    11461 ataaagtagc gatttgcgag caggtagaag atccaaagac gactaaaggg atggtcaagc
    11521 gcgaagtgat ccagctagtc actcctggta cagtcatgga cagcaaagga ttgtcggcaa
    11581 aagacaacaa ttttttaaca gctgtagtta gtcaaggaaa tgaatttggc tttgcttatg
    11641 ccgatttaag tacgggagaa ttgaagacgg ctcggttgca tgatgaagaa gctgttttaa
    11701 atgaagcctc tgcattgcag acaaaagaac tcgtattagg cagtgagatc actgataccc
    11761 ttcgtgaaca gctaagcggg cgtttagggc tagtcttttc tcaacaaaat gagatggaag
    11821 aaaacgcgga atttagcttt ttgacaagcg aactagtcga tccgctggaa aaagaagcaa
    11881 ccggcaaact attgacttat ttatcggtga cacaaaagcg gagtttagct catatccaaa
    11941 aagcagtaga ataccaacca gatcattttt tgaaaatgga ttattattca aaattcaacc
    12001 tagaattaag ccaatctatt cggactggga aaaagcacgg cactcttcta tggttgttag
    12061 atgaaacaaa aacagcaatg ggtggccgtt tactaaaaca atggctagac cgtccgctta
    12121 tccaggcaaa acaaattaaa gcaagacaag aaatggtcgc ttctttgcta gacagctatt
    12181 ttgaacgtat cgatttgcag tcagcattaa cgaaagtcta tgatctggaa cgcctagcag
    12241 gtcgagtagc tttcggtaat gtcaatgggc gagacttgat ccagctgaaa acttctttag
    12301 aacaagtgcc aatgatcaga gggttgattg aaggaatcga tcaaggtcaa tggcaaagtc
    12361 tgctttcaga aatgcagccg atggaccatc tcgtccaatt gatcgaccaa gctatccaag
    12421 atgatccgcc gttacaaata acggaaggaa acatcatcaa agatggattc aatgagcagc
    12481 tcgatatgta ccgttctgct atgagaaacg gaaagaaatg gttggcagaa cttgaagcaa
    12541 aagagcgtca agaaacagga atcaagaact taaaaatcgg atttaaccgc gttttcggtt
    12601 attatataga aattacaaaa gcaaatcttg gaaatgcaga actggagaag tatgaacgaa
    12661 aacaaacttt agcaaatgca gagcgtttca tcacaccaga actaaaagaa ttggagacac
    12721 aaatcctcga agcagaagaa aaatctgttg atttagaata tcagttgttt ttagctgtga
    12781 gagaagaagt caaaaaggct atccagccgc tacaagtact tgcaaaagca atcagtgcag
    12841 tagatgtgct acaaagtttt gcaacgatca gcgaacgcta tcagtatgtt cggccagaac
    12901 ttgtcagtga caagcatcag cttctgatca aagacggacg acatcctgta gtagaaaaag
    12961 tattaggaca tcaggaatat atccctaaca gcgtagaaat ggcagaagac gaaatgatct
    13021 tgctgattac aggaccgaat atgtctggta aaagtacgta tatgcgacag ttggcattaa
    13081 ctgttctgat ggcgcaaatg ggctgtttcg ttccggcaaa acaagcagtt ttacctattt
    13141 ttgatcggat ttttacccga attggtgcaa gtgacgactt aattgctgga caaagtactt
    13201 ttatggtaga gatgatggaa gccaatcaag ccctgcgtta tgctacgcca aacagtttga
    13261 ttttgtttga cgaactaggg cgaggaacag caacctatga cggaatggcg ttggcccaag
    13321 caatcatcga atatatccat cgtcatgtac aagcaaaaac actcttttct actcattatc
    13381 atgaactgac ggtacttgag aaagaacttc cgcagcttaa aaatgtccat gttggagccg
    13441 ttgaaaaaga cggagaagtt gtcttcttgc ataaaatgat ggatggacct gcggataaaa
    13501 gctacggcat acatgtggca aagatcgcag gattgccttc caatctacta gaacgagcag
    13561 cagatatcct gcatacgcta gaaaatggcg ataacggaca ccatactgtt ccagctgaag
    13621 tagaagagaa aactaaaaca gccaaacagg agcaaataaa accacctgca gaaaaagtaa
    13681 atcaagacca tatacaagac cgtgtaaaag aagaaaacca acagctttct ttattcagtg
    13741 aattatccga aaatgaaaca gaagtcattg aatcactgaa gcaaataaat ttactagaaa
    13801 tgacgccaat ggatgcacta aacacattat atgaattaca aaaacaactg taggaagaag
    13861 gcggatatcg atggccaaaa tccaagaatt atctgaacgt ttagctaatc agatcgctgc
    13921 gggagaagta gtggagcgac cagcttccgt tgtgaaagaa ttagtggaaa atgcaattga
    13981 cgccggcagt actcagattg atatcttagt tgaagaagcg ggactgcgga cgatccaagt
    14041 gattgataac ggagaaggca ttttggcaga cgacgtagag aatgccttca agcggcatgc
    14101 gacaagtaag atccataatc gcgacgatct ttttcgcata cgaacgctgg gctttcgagg
    14161 ggaagctttg ccaagtattg cctctgtttc tgaaatgact ctggaaacgg cgaatcagga
    14221 agaaaaacaa ggcacctatc tgtcgctgaa aggcggagaa gttattgagc atcgaccagc
    14281 accactgcgt caaggaacga agattaccgt cagcaatctg tttttcaata cgccagcccg
    14341 cttgaaatac gtgaaaacac tgcacacaga attagcgaac atcggggaca tcgtcaatcg
    14401 actggcattg agtcatccat cgattgcttt tcgtttagta catgatggaa acaaaatgct
    14461 ggcaactgct ggaaatggcg atctgaaaca aacaattgcg ggaatctacg gattatctac
    14521 cgcaaaaaaa atgctgaaaa tcgaaggaaa agatctagat tttgagttat ttggctatgt
    14581 ttcattgcct gaggtgactc gtgccagtag gaattactta tcgacgatca tcaatggacg
    14641 ttttatcaag aacttttcct tgaataaagc aatcgttgca ggttatgggt caaaattaat
    14701 ggtcggtcgt ttccctattg ctgtattgga aatcaaaatg gacccgcttt tagtagatgt
    14761 aaatgttcat ccgacgaagc aggaagtccg gctgtcgaag gaaaaagaac taacagagct
    14821 aattagtaac gccattcaaa aagcattgtc tcaagaaaat ctgattccaa gtgcagcgga
    14881 taatctacgg tttaagaaaa aagtacctga tcagcctaaa acagaacaaa tcgaaatcga
    14941 tttgtcctac gcttttgaag aagaaaaacc taaaaagcca agtagtttga attttgatcg
    15001 agagacaggt acctttttcg tagaagaact aaagaacaca tttgttgaca gaattgttga
    15061 taagtctgtg gaaaatgttg aaaactattc tggtttttct gaagaaaaca ccacttatcc
    15121 agaaaaaaca gcgaaaacgg tggataagtt tggtgaaaat gttgataact ttgtagaaaa
    15181 aacagtggaa aaatctgaaa agaaagaatt tcccattgtg gataacatgg agaaaacaaa
    15241 tgaagaacaa gcagataaat ccgtagaaga ggatgaaaag atttacgagg aagaattgac
    15301 actccatcct gaatttgatt tcactcaagg aaacgacaaa acattagaac aagccatcaa
    15361 gaaattagaa acggaaaaac cagtacaacg ttttcctcag ttggaatatt ttggacagat
    15421 gcacggaacg tatctttttg cccaaagtag cgatgggttg tacatcattg atcagcatgc
    15481 tgcccaagag cgcattaagt atgaatattt ccgggaaaaa attggggaag tatctgatga
    15541 tctgcaagaa ttgcttgttc catttgtgtt agactatcca aacagtgatg ctttgaaatt
    15601 aaaagagcaa aaacacttgc tagaagatgc agggatttat ttagaagaat ttggtcaaaa
    15661 cagctttatt gtacgggccc atcctacttg gtatcccaat ggagaagaag aatcgattat
    15721 tcgggagatg atcgatatgc tgctgacaac tggaagtgtg agtgtaaaaa aattccgtga
    15781 agcaacagca atcatgatga gttgcaaacg atcgattaaa gccaaccatt atttgaatga
    15841 agcacaagca cgtgtgctgc tgaaggatct ggcacgatgc gaaaatcctt tcaattgtcc
    15901 ccatggccgt ccagtattga ttcactttac caattcggat atggaaagga tgttcaaacg
    15961 aatccaagac ccgcattaag tcaaagagaa gagggaaaac atgaagattg tattagcatc
    16021 ccaatcacca agaagaaaag agttattggc tcatatcgtt tcagaattcg agattgaacc
    16081 tgctgatatc gatgaaacgc catttccaga cgaacagccc gtcgattatg ttcgtagaat
    16141 ggctgaagaa aaagcacgaa ctgtctggga acaagatgaa aaagaagacc atttagtgat
    16201 tgccagtgac acgactgttg ttctcaatca agagatcatg ggtaaaccag aagatctggc
    16261 tgaggctgaa ttcatgctga aaaaactaag cggggaaaca catactgtat atacagctgt
    16321 tgttttaaaa acaaaggaac gagaagaacg gatactagca gaagcacatg tcacttttta
    16381 tcctttgaca gacgaagaga tcaaacgcta cttggagacg ggggattatg cggataaggc
    16441 aggggcatac ggcatccaaa atgctgcgag tgtattcgtc aaagaaattt ctggagatta
    16501 ttacagtatc gtaggatttc cgattggtgc tgtcaatcag gcactgaaaa cattcattta
    16561 aacaaaaaag cggactatct gattttcgat tgaaaatcca tgatagcccg ttttttttat
    16621 tgaaaagatt acttatctac tctgactaag attttacttc agctttaccg actgcttcgc
    16681 ccgggcgaac aagtcctgat tggtcaagag aaagtcctgc aactttttca ttattggtca
    16741 aagcaacaat aatgtcagtt ttcttgccag cttgttctat ttctggcaaa tccatttcag
    16801 caatcagggt ctctggtgtg acaaggtatc cttctttcac gaatacattg aaaggaacac
    16861 cctttagttc aacagtatct aatcccatgt gaacaagtac ttccagcccc tcattagaaa
    16921 gaataccaat ggcatgtttt gtttcaaaga cactcgtcac tttaccgttt actggtgcat
    16981 agactttgcc gtttgacggt tcgacagcat aaccgtcacc catcattttt tgtgagaaaa
    17041 ctgggtcatt tacttcagtt atttccttga tggtccctgc agcgactgcg aataatgttt
    17101 cttttgttgc aactgccgta ccagttgctg aaacaggttc gaaagactgt ggcgttgctg
    17161 ttgcgccatt tgctgtttga agttgtacat cagcagcatt ttcaggaaca gcaggatcaa
    17221 tcttattcaa aattccctga cgtctaaaga tgatcgtcaa gccaaatgga atgatgacag
    17281 caatgatcat tgcgatgatg aaaggtaccc atgtttctgc ttggatagct agtattcctg
    17341 gcaaaccgcc tactccgatc gcgttagctc gaacacccat caagttagca aacatgccag
    17401 ctaatccaga gccgaccatt gcagcgacga aaggatagac gtatttcaaa ttgattccga
    17461 acatagcagg ttcagttacg cctaagtaac aagaaatcat tgctggaatc gagatttgtt
    17521 cttctttttt attcccacga tgtaagaaga tgatggctaa gactgcagag ccttgggcga
    17581 tatttgataa agcaatcatc ggccataaat tcgttgatcc gaaatctgca atcagctgca
    17641 tatcgatggc attggtcata tggtggagac cagtaatcac taaaggagca tacaggaatc
    17701 cgaatacggc actaaacaac cagctgatag aagacgtcaa tccagtattt acgatatttg
    17761 agatccagct tccgactgtc cagccgatag gacctaaaat aacgtgtgca gctaaaacag
    17821 ttggtaacaa tgaaaacaat ggaacaaaaa tcatcgagat cgactgaggg atatatttgc
    17881 ggaagaagat ttctagatac gctaacataa accctgccag catggctgga ataacttgcg
    17941 cttgataacc aatcatctgg acttgagcaa aaccaaaatc ccaaaatgga atatctgctg
    18001 cggctgtgga agctacacta taagcattta ataattgcgg agaaactaac gtaattccta
    18061 aaacgattcc taatatttgt gtagtaccca tcttttttgc aatactccaa gtgataccta
    18121 ctggaagaaa atggaaaatt gcttcaccgg gtaaccacaa aaaggcattg acaccattcc
    18181 aaaacttcga gtgttcaacg attgttccac caagactttc aaactggata ccttcaagta
    18241 catttctgaa tccaaggatc aatccaccga caatgattgc aggaatcagt ggtgtaaaga
    18301 tttctgctaa aacggcaata gcacgttgaa cgggatgaag gttttgtttt gcagctgctt
    18361 ttccttgttc tttggaaacc ccttcaactc cagatactgc aacgaagtcg ttataaaaag
    18421 tagaaacatc gtttcctatg atgacttgga actgtcctgc attcgtgaac atccctttta
    18481 cgctaggtat atcttcgatc gctttttcgt ccgcttttcc tggatcattc aggacaaaac
    18541 gcatacgagt cgcacaatga ctaactgcag caatattttc ttttccgccg atatcatgta
    18601 acagcttctc ggcatctgct tgatattttg ccatatcaat aaaccccttt ctcttaactt
    18661 gtctatgcaa gttgtttctt catttactat actttttttc ggagagaatt gcaagcgttt
    18721 tattaaaaag tacgagagaa aatgatatcg ttttaaaaag cttaaaataa gcttttctta
    18781 aaaataggaa cattgaaata caaaaagagc tgtagtatag tgaagaaatg atggaagaac
    18841 gagtgaggga aaaaacatga ataagttcaa tgaaattttt ttagatttgg aacagaaaat
    18901 tttagcgaaa gaatatcctc cgcattcgct tttacccagt gagaaccaat tgatcaaaat
    18961 ttatggtgtt tcacgagaaa caattagaaa agcgctgaat cttttgacta cggaaggtta
    19021 tattcaaaaa aaacaaggaa aaggttcgat cgtactggat cggaatcgct tcgactttcc
    19081 tatttctgga ttgactagct ataaagagct acaggagacc caacgtattc caagtgaaac
    19141 gatcatccat acgttagaag aaacagaagt gacaaaagca ttgaacgaga tcactggctg
    19201 ggagatcggt gcgcctgttt ggcatttgat acgcgaaaga aaaatcaatg gcgaagtagt
    19261 tatattagac accgattatc tattaaagga aatcgttcct attttaactc cagcacaagc
    19321 acaaggatcg atctatgaat attttgaaaa tgagctttct ttgacgattg cttacgcgca
    19381 aaaggagatc acagtagaag aagtaacgga aatcatgaaa acagcgatgg atcttcacga
    19441 tgacacttat gcagtagtag tcagaagcct cgttcatctg gaagataccc gctgtttcga
    19501 gtattctgag tcggttcacc gattagataa attccgtttc gttgagtttg cccgacgccg
    19561 aaaagtgtaa atagttcaaa agaaagcaaa ttgttggcat ctgtccactt tggcgctatg
    19621 ataggatcac aaagggggca tttttaatgg ataaaccaat aagaccagaa aaagaagaac
    19681 tgaaagaaaa gttatcaccc atggcttatg cagtcacaca agaaaatgca acagaacgac
    19741 catttagcgg gaaatatgat gatttttacg aaaaggggat ctatgtagat atcgtcagcg
    19801 gtgaaccgtt attcagctct gcagaaaaat atgatgcagg ttgtggctgg ccatcattca
    19861 gcaaaccaat aacgaaaaga caagtgcgcg aaaaagccga tttttctcat ggcatgcatc
    19921 gaatagaagt tcgaagcaaa gaagcagatt ctcatctcgg acatgtgttt accgatggac
    19981 cagtagatca aggtggtcta cgttactgca tcaattctgc ctcactgaaa ttcattccat
    20041 atgaaaagat ggatgaatta ggttatgggg aattcaaatc acttgtagaa taatggaaat
    20101 acacaaagag cggtacaata cggggattta ctcgatcgtc cgctcttttt ttattcaagc
    20161 gattgctatt tgaaagaaac gctccctaga ctcctttttt cacaaggtga aatgtgctac
    20221 aataaaggga acgtatgtgt gcaaaagaaa gaggactaga atatgtatga atatctgaca
    20281 ggtgtggtta cctttatcaa cccctattac atagtagtag aaaccaatgg tatcggctac
    20341 cagatcgcac taggaaatcc ttaccgctac agtagcaaac taaatcaaaa aataaaaatt
    20401 tatgtccatc aggtaatacg tgaagatgcg catcttctgt atggatttga ttcgctagaa
    20461 gaaaagcaac tgtttttgcg attagtaagt gtttcaggaa tcggtccgaa aagtgccctt
    20521 gcaatcatgg caagcgaaga ccactccggt ttgattcaag cagtagaatc cagtgatgtc
    20581 acttatttga cgaaatttcc aggagtaggg aaaaagacag cacaacaaat gatcttggat
    20641 ctaaaaggaa aattcggtga gctgagtatc gatacacctt ttagtctatt tgatgaagca
    20701 aacacaaaag acgctacagc tctatctgaa gcaatggaag ctctctcggc tcttggttac
    20761 agtgatcgag aaatcaaacg tgtagaaaaa caattaaaag aagtagataa tcagacaacg
    20821 gatgagtatc tacgccaagc actcaagcta atgatgaaaa aataaggagg agaccaaatg
    20881 acagatgaat acttgttatc accagaatct ggcgaaaatg aactgagttt ggaaaaatct
    20941 cttcgaccac agctgctttc tcaatatatc ggacagagaa aagtcaaaca agaacttcag
    21001 atttacatcg aagctgccag aaatcgggaa gaacctttag atcatgttct gttgtacggg
    21061 cctcctggat taggaaaaac gacgatggcc atggtcattg ctaatgagat gaccgtaaat
    21121 attcgtacga cgagtggccc tgctatcgaa cgtccgggtg acttagtagc aatcttgaat
    21181 gaactggaag caggggatgt cctgtttatc gatgagatcc atcgattacc tagagtggta
    21241 gaagagatgc tttattcagc tatggaagat ttctatgtag atatcatggt aggacaaggg
    21301 ccaaccgcac atccggttca tttccctctt cctcccttta ctttgattgg cgcgacgaca
    21361 cgggcaggta tgctttctgc acctttacga gatcgatttg gcatcatttc tcatatggaa
    21421 tattatgacg aacaggatct gcaggagatc gttttacgtt cttcggatat ttttcaaaca
    21481 gagatcattg aagaaggggc attggaaatt gctcgccgat cacgaggaac gcctagaatc
    21541 gctaatcgct tgctcaaacg ggttcgtgat tttgcgcaag tccaaggaga cgggaaaatc
    21601 gatcgtccta tagcggatca ggcacttact ttgctacagg tcgatcaggc tggattggat
    21661 tatgttgacc agaaattgtt gcgaacaatg atcgagttat atggcggcgg accagtaggg
    21721 ttaagtacgc tttcagtaaa cataggagaa gagcgtgaga cggtagaaga tatgtatgaa
    21781 ccgtatctga tccaaaaagg atttttaaag cgtacaccta gagggcgaat tgctactgct
    21841 tatgcctatg aacattttgg ttacgactat catatatgat ttttgctttt agattggagg
    21901 aaaatgaatg agtgatacaa cacgtacgaa acaattgatc aaaaacgtat tgattgattt
    21961 gtgccaaacg caatcttttc gaaaaatcag cgtccaaaaa atcgcaaacg aagcaaaaat
    22021 caatcgacaa acattttatt atcattttac agataaatac gatttgcttc gttgggtcta
    22081 ttgtgaggat gcattgcatt atttagatcc acaatgtctt tcacttgata attgggaaga
    22141 gcaagcattg aaaatgctga aagcaattgc tgagaagaaa gaattttatg caaatactgt
    22201 gctttctgac ccagaaattt tacaaaaaga gttttctcaa ctgatccaaa aatcatttat
    22261 caagattttt gaacaaatgg atgaagaaag acaactttct gcaagagaca aactatttta
    22321 tgctcgtttt ttttcttacg gttgcagtgg tgtattagtc aattggatca cgaatgaata
    22381 tgaagaaaca ccgatggaaa tcgctatgca gcttttccgt ttagccaagg atacggaatt
    22441 atattcttat cgtctttatg caaaagaaga gttggaagaa cagtaataga aaaatttttt
    22501 gttggaaaag caataatcgc taaaaggaga tggggaaatg acaaaaattt tatttgtttg
    22561 tttgggaaat atttgccgtt caccgatggc agaaggcttg ctgagaaaac gaatagcatt
    22621 agaaggaagg gaagcagaat tttttgtgga ttctgctgct acaagcacgt atgaagttgg
    22681 aaagacaccg caccctggaa cgaaaaaaat attaaaccaa gaaaaagtag atatgacgaa
    22741 tatggttgct cggcaaatca caccccacga ttttgaaact tttgattgga tcattggcat
    22801 ggatcaagaa aatgtagaag aactgaaacg aagagcacca cgctcagcgc aggggaaaat
    22861 ccatttgttt ttaagtagca ttcctggaaa agaaaaagaa aatgttcccg acccatacta
    22921 taccaataac tttgatgaga catatcactt gatcacagaa ggcctgaatc attggtggaa
    22981 tatttggatt gatgaaaata aaataacaaa caatttgtaa agttaacgct ttctttttaa
    23041 ggcgatgtta gagcatttcc ttgttttttt gtaaaatgtt aggtaaaata aaattaatta
    23101 agtaacactt tcttagctaa aggaggagtg cattcgatga acgaagagac agtatcgcca
    23161 atgaagaagc ttacgaagtt agttactcat acttcgtatc aactttttga ttcttttgta
    23221 aatgacactg aagaacatgc taagaatgta cgattgcaag gaaagtttat tcttgagctg
    23281 caaaaagctg ctactgaaca tagtctagtt atcttacaag taagagcaaa tcgtttgagt
    23341 agcaagtatg aaacgatctc aggctgggtg gcgacaaaaa cggtcgaaaa agaccgagtg
    23401 atgatccgcc tacaaaacga agagcagcag atccggatgg ttcctgtaga acaaattgaa
    23461 aaaataacaa tcctttcacc agcaggggaa caggaacggt tatcaaaata atttatacca
    23521 gatagaaaag cacgtatgag cttgtaccat caatcattac taatcaaaaa taaccgaatg
    23581 ctttaagctg atatcagtaa aacggaacgt tttaggatga gtatcacagc atgacagcat
    23641 tgggttgatt agttgaatcg attggatggt acaagttttt ttgataaaaa aaggtcctgc
    23701 tagccgggga gctagcagga taaggagtta aaaatgaaaa agtgttgtta gggttgtttg
    23761 ttggtatgct tatataatag tcactagttg tgaatatttt gtgacgaaag ttttcgaaag
    23821 ttgttaagtt tttttgcgaa aactattttt atatcatata tatgtctaaa atctatatta
    23881 taaaagaaat gttgtttgat cagcttctct tcggtattag ttcaaaacaa aacggcaaag
    23941 tatatggagc tactttgccg ttttgtttct ctaatactca ggtcagttta tagacgctca
    24001 ataaacggtg ttcaaaagcc agtttctcgg tattaagtca aatttatgca aaaatgtgag
    24061 aagccatttt caaaaaatat ttcttaatac tcgaaactga gcggcttttt cacgacctct
    24121 caataaacag tgttcaagag acagcctatc ggcaataagg ctgaacgtct ctttcacaac
    24181 ctcttttatc aatctgctac ttcttctttc ttagcgaaac tccaaatcag tccgataaca
    24241 aaaccgataa ctgctggtac gatccacccc atccccaatt tgaaaaacgg caagtagctt
    24301 tccgcaacat ataaaagatt ttgaacaata ggtgtttgtt tgatagtttc tgggcaagcg
    24361 ttcaacccat caaaaatcga agcaatcaat gtaaaataag tagtcattcg ataaacagcc
    24421 gtacgctgct taaacaaagg accaactaac actagtaaaa tcagtgtcat tgctaatgga
    24481 tagatgaaca tcaaaacagg caacgaaaat tgaatgatat tcgtcaagcc tacgtttgcc
    24541 gctaaacaag gaaggatact agcaagtgca acaaagaatg cgtaatttct ttgcggaaac
    24601 aaatctgtga atgtttctgc aaaagctgta atcaaaccaa taccggtctt caagcaagct
    24661 aatataacga taaatgctaa taagatactg ccataagtac ctaaataatg atcagcaatc
    24721 tgagccagcg tgatcccgcc attttcactt agagcaaagc tacctaagct catagcacct
    24781 aaataagcga gcaaagtata aatgattccc atcaatataa tgctgatcgc accagatttg
    24841 atcgtgtctt tagcgatttc agcaggtttt gttacaccca tgttttggat tgttgtgaca
    24901 atgatgatcc caaatgctaa agcagcaagc gcatctaatg tgttatatcc ttgagtaaac
    24961 cctgtgaaaa aagcatgctc ttgataattt ggctgaatag gcgcttgatt tacagaacct
    25021 agtggattca aaaaagcaag gagaagcaaa gcacctaata aaaccaaaaa tgcaggattc
    25081 aggaactttc caacataatc taatatcttt gtcggttttc ttgaaaacca ccaagccagc
    25141 acaaaaaata caatactgaa aattgctaga tatagcgtct gtctgctagg atcgataaat
    25201 ggtgctaaac caatctcgaa agatgtggtt gcaaggcgag gtaaagcaaa aaacggtccg
    25261 ataactaagt aaagcaagat ggtaaaaacc atcgcatatg tttgatttat ccgttttgct
    25321 aattcatata cacctgagct tttcgataca ccaatggcaa tcacccctaa gaagggaaga
    25381 ccgataccgg taaccaagaa acctagattc gcccaaaagg tagcagcgcc tgcttcttga
    25441 cccaaatgaa cgggaaagat aagatttcca gcaccaaaaa atagaccgaa aagcatggag
    25501 cctataaaaa gatagtcttt aaatgataat ttttttgtca tacataactc ctttacggtt
    25561 tttttaaaag taacaaaatt tcgaaaaata tgcaacaatt ttcagaaaat ttcctatata
    25621 aaacgacggt tatttaataa cgtaagtgat aaaataaaag cgctgaatca tctgaggagg
    25681 aatcatcgtg acaaagtcga gattagaagc atttactgat ggagtggtag ccattgtttt
    25741 gagagttctt gtattagaga tcaagatccc taatacatct agctttcatt ctttatgggt
    25801 catccgaaat acattattag cttataccat cagctttata tttgttgcgg tgatctgggt
    25861 gaaccatcat cgtatatttc agatggcaga acgaattaat taccgagtgg tctggtcgaa
    25921 tatctttttg ctcttttggc tgactttatg tccttctgtt actagttggg tcgggcgtaa
    25981 ccctgaagct ttttggcctg agatggctta tgtcttagta tacacgatgt ggagtttttc
    26041 ttttggtatc ttgatgaggc aaatcatgaa agcaaataaa ccagattccc atgtcgtgag
    26101 agttttgtca aaggaccgtc gaagtcttat ctccatgatg attaacttat gcttgattgc
    26161 cggtgtcttt tttgtaccgt tgatcgggtt attcggacgt ttttttgtat ctggtatttg
    26221 gattttttcc tataaaaaag cagatgccta ttatcagcgg ttgtttccgg ggaaatagaa
    26281 aagaggctgg gacagaagct tttaactcca agaaataagc cgaaatttca caaaaattta
    26341 agaagcaatt ttcgtaaatt ccttcttatt tctcgaagct gaccacttct gtcacaacta
    26401 ctttcttact tcttacgttc atatttcata tgatagatta gtaatagaag caagaaccac
    26461 acaggtgtta gtaataaagc gattctcgta tcttttccta ggaacaagac gacacacaca
    26521 aaggccatgt aaagaaatac cagataatta ctaaatgggt acaacggcat tttaaatgaa
    26581 tgagcttttt tgccgaggat acttttacga tatttcatgt gcgtgtagac aagcatactc
    26641 cagataaaca agaaacaagt agtggcaata ctgcttacta gtgtgaatac ttcactaggc
    26701 atcacgtaat tcaagataac agaaatgaaa atgacgatag tagaaaatgt caaagcattc
    26761 cctggcacat gatgtgttgt taactttttg aattttttag gggcactgcc ttcttgcgct
    26821 aaagaacgaa gcatacgtcc tgtactatat attgcactgt tgcaggcaga agctgctgca
    26881 cttaatacga ctaaattgat caaggaagca gcaatcgtga tcccaatttc cgaaaatact
    26941 tctacaaatg gactgttatc tggattcaag ctgttccatg gatagattgc cataatgaca
    27001 aaaagagatc ctaagtaaaa taagatgatc ctgataggaa tattattgat agcttccggc
    27061 aacacttttt caggattttc tgtttctcca gcgactaatc caactaattc tatcccagca
    27121 aaagcaaagg ttaccatttg gaaagctaag ataaatcctt ttgcaccagt tggaaagaat
    27181 ccgccatgag accatagatt cgtgatactg gctgtgccaa tatctgtcgt atagtgggtg
    27241 aggatcatat aagctcctac gaggataaag gcaatgatcg ctacaacttt gatcaatgca
    27301 aaccaaaact ctaactcacc aaacaatgag acagccacca tattcaagca aagaagaaga
    27361 cctaatgcaa tcagttcagg aagccactga ggaacaccag gcgcccagta gcgtacatac
    27421 attccgatgg ctgttaaatc ggccattgca atcgataccc agcagaacca atacgtccag
    27481 ccagtgatga aagccgcttt tttgccaaga tattctgcaa caaaatccag aaaagaatgg
    27541 ttattggtgt ttgataacag aagttcgcct aacgcacgca taatgaaaaa acagatgcat
    27601 ccagtaataa gataggcgag caatatcgaa gggccagcta gctggataga ctttccggaa
    27661 cctaaaaaca accccgttcc aatcgctccg ccaatagaaa tcagttggac atgtctattt
    27721 ttcagtccac gctgcagttc ttgctcttca ttcattttta aatcatccta actaaaaaag
    27781 tttaattact tccatattaa aagagttttc tgaaaaacac aactaagatt ccaaaatttt
    27841 cagaaattta ccttttatga gtaattcata aaaaagaact gcggtaaaca ccgcagctct
    27901 ttgtcccaat cagctattga tcctaagcat ttaaaatacg tgaaaggaat tcttttgtac
    27961 gttcttcttt cggatggaca aagatatctt ctggtgtacc ttcttctgca atcacacctt
    28021 tatccataaa aatgacacgg tcagatacat cttttgcaaa ttccatctca tgcgtcacga
    28081 taagcattgt caagccagta tgtgctaagt ctttgatcgt attaagcact tcgccaacca
    28141 tttcagggtc taacgccgaa gtaggttcgt cgaatagcaa tacatctgga ttcattgata
    28201 atgcccgagc aattgcgaca cgctgtttct gtccaccaga taattgtgct ggtttggctt
    28261 cgatataacg atccatacca actttttcca gattttcgat tgctactttt ttggcagttt
    28321 ctttatctcg tttcaggaca gttgtttgac cagacataca gttttccaag acattcatat
    28381 tgttgaacag gttgaaggat tggaaaacca tacctagatt cgttcgatat ttaggtaaat
    28441 tatatttagg agctaataca ttttctccat tataaatgat ctcgccgcct gttggttttt
    28501 ccagtaaatt gatacagcgc aagaaagtag atttaccaga accggaagaa ccgatgatcg
    28561 tcacaacttc acctttattg actgttacgc tgatatcttt caatacttca ttttcaccga
    28621 agctttttct tagatgtttg atttcaataa ttttttcatt catgattctt cctccttatt
    28681 cctgcaaatt tgaattgtcg atttcttcaa gcttggtata agctgaagga ccatcgattt
    28741 tcttttctac cgcccgcagg attctggtga tcgtaaaggt catgactaag tagatgatcc
    28801 cgacgatcgt aaatgtttgg aagaattgga aattcgcacc ggaagcagag tttccttgga
    28861 agaacaaatc agctacgccg attacactta aaactgctgt atctttgata ttgataacaa
    28921 actcatttcc tgttgctggc aagatattcc gtaaaacttg tggaataaca acttttctca
    28981 tcgtttggcc atgggtcata ccaatggctt gcgcagcttc gaactgccct tcatctactg
    29041 caaaaatccc cccacgaacg atctctgtca tgtaagctcc agtattgaga gagacaataa
    29101 acaaagcggc aatcgttcgg ttcaatgaaa tgccaaaagc gagtgccaga ccgtagaaga
    29161 tgaccattgc ttgtaccatc atcggtgttc cgcggaatac ttcgacatag atagaaagaa
    29221 gtgcatttcc gattttttgg aagaagcgag tcagtgcatt tcctgattca ggtaccgaac
    29281 ggaagacacc aatcagtaat ccaagtgtag taccgacaac tgtcccgatc aatgcgatga
    29341 acaaggtaag tccagcacct cgtaagaaca tattgccgta ttgtttccaa atcgtagtga
    29401 aatcagaaat gatgccaggt ttttcttcac tatcagttgc agcaggctga tctttgactg
    29461 cttggtccat aattttggtt cgttcatcgt tagagatgcc agaaagaatc tggtttactt
    29521 tttggatatc cgggtcgcct ttacgcatac caacagaaat ctgaacatct tccgggtttg
    29581 tctggaagcc atctgcaccg ctgaattcaa gcatttccaa gtctttgttc acactagttg
    29641 ccgttacacc ttccggacgt tcgctgacat aaccatcgat cattccagaa gctaaagctg
    29701 ttctcattgc tgagaaatta tccattgctt gttgtttctg cacatctggt atctgatcga
    29761 tcacagtata gtggaatgta tttaactgag cagtaatctt tgctccagaa agatctgcta
    29821 aactttttgc ttttgcatat ttgctatctt tttgaactac tactactaat tgtgattcgt
    29881 aataaggatc ggtaaaatca atttcttttc gtcgttcagc agtagggctc attccggcga
    29941 tgatcgcgtc gatcttgcct gattgaaggg caggagccag accatcccat ttcgtttgga
    30001 cgatgactaa ttttttccct aaaccatctg ctactttttt agcgatttga acatcataac
    30061 cgccggcgta actattttgg ccttgaattg gcaaggcatt attctcatct gtttgttgag
    30121 accagttgaa gggtgcatac ccagcctcca tacctacgcg aaactcatcg ctcggtgttt
    30181 tttcatctgc atttgccaga gatcccacac tgaatagtga gaagacaaaa gcaaatagta
    30241 cggcaactga aaccatattt tttttcattt ttttctccct ttctgattat atgatacacg
    30301 agcggtctag atgaaatgcg gtaaagcttt atctgaaaaa ataaaaagcg accgatttat
    30361 agatataaaa aggccgctaa aattccataa ggtgataaac ctctcacaaa acatagcgca
    30421 acttagcatc actgctaaga cagtccgcaa gctcttaact tgcgtcccaa catacactcc
    30481 aagcaaaaaa gtgcacattt cggcgatcct ccctattcct gcttctccat gtttgcttca
    30541 ctccacaggg ttaatgattc tcgcgacctc tacctcattg attgaggcat ctcgtattca
    30601 gttatttata caaaaaaagt ttacgatact cgagaggctt tgtcaatcta taactgctgt
    30661 tttttgaaaa aatactgata aatatagaaa tctttacttt taccgaaaaa acaatcaaaa
    30721 tgtgaatcat ctatccattg caaacgatag tataattata cacaaaaatg tatgtaatac
    30781 aataaaaaaa gaactagaac agaaaatttc ctgtgtccag ttccatctcg atcatttaag
    30841 ctgccgcttt ctttggctca cgtcctagga tcgcttgcaa aagaacaacg acgccataaa
    30901 tggctaatat tagataaatc aaacttgagt attgggtgat tccccagccc catgttcgat
    30961 atacggctaa tgtaatggct aaaacaattg cggcaatcac gttgaataaa gcaaaagccc
    31021 aaagatttcc attttctttg cgtacaagat aaaaaacaga gaaataaacg cttaacgcta
    31081 accaggcgat acaagccaga ataacgcccc aataaataaa gaatggtaac atatcgattc
    31141 acctcacttt tatacagcag tattgtaaca cgttttcatt cttttgtcag tgaacattgt
    31201 gataaattgt tcaaatgccc ataacacttt tttattccca tttttctgac ttttcaacaa
    31261 taaatttgtt cgagtatggg ctataatgga aagtgaggtg acaaaacatg aaacaattaa
    31321 cagtagacga agcagcaaaa gagatattag cttatcagca aattacattt ttgaccggtg
    31381 caggggtatc cacaccttct ggagtgccag actatcgatc tttgtcagga atctaccacg
    31441 ggatggagca gccggaatac ttgctgagtc atcaagcaat ggtgaatgaa ccggataaat
    31501 tctatcaatt tgtcaaaaag atttatcatc ctgaagcaaa acccaatatc attcatttgg
    31561 aaatggcaca tctagcgaaa gaaaaaaatg tttgggttgt ttcccaaaac atcgacggtt
    31621 tgcacgcaaa ggctaaaagc ccgcaactcg tcaattttca tggaagtttg tatcaatgtc
    31681 attgtcgaaa atgtcaacaa acggtagact ggaaagaata tcttcacagc gacaaacatc
    31741 aagcatgcgg aggacaaata cgcccagaca tcgtgttata tggtgaaggg tttcaagatg
    31801 gagtcatgga gcaggcggct tatgccgtca gccaagcaga gctgatcgtc attgttggaa
    31861 cgagttttca agttcatccg ttttgtgatc tggtacagtt tcgccagccg tcagccaaaa
    31921 tcttagtaat caatcaaacg cctgtttatt tagcggagcc ttatacgttt attcaagaag
    31981 acggagcggt tgttttcaaa aaaatacaag aattaggagc agattatgac tgaattcaaa
    32041 accgaaaaag aaaaaatgat tgcaggcgag ctttattttg ccaatgatcc tgagctggtt
    32101 gccgaccgta tgtttgcaag aagtcaaagc caaatcatca accaagcaga atcagcggaa
    32161 ctgcgatccc aattgttgaa agagactttt ggccgtacag ggaaaaaaat ctatatggag
    32221 ccagttatca attttgatta cggatataat atatttgttg gggagaattt ttatgcaaat
    32281 ttcaattgta catttttaga tgtcagcacg attgaaatcg gtgataactg catgttcgct
    32341 ccgaatgtcc agctttacac ggcgacgcat ccactacatc cagtgaaacg taacagcggt
    32401 ctggagtacg caaaacccat taaaatcggt aataatgttt ggttaggcgg aggagttatc
    32461 gtcacgccgg gtgtcactct aggggacaac gtagtagtcg gcgcaggttc ggttgtgacc
    32521 aaatcttttc ccgacaatgt agtgattgca ggaaatcctg ctcgtatcat caagacagta
    32581 gaggaagaac taacagaaga gtctcttgaa acattacgtc ataagatcga tatgatcgat
    32641 cgagagttga ttgctttatt agaaaaaaga atggatacgg taactaaaat aggacaagtg
    32701 aaaaaagaag aaaaccaagc agtttatgat gcaaaaagag agcagcaagt attggataaa
    32761 gttgttagtc tgctgaaaaa taagggatat aaggaaacaa taacagatac gtatgttgat
    32821 ttgatgaaac actcgcgcga ataccaaaac aaaatgaagg aggaataagt gtgatcgaag
    32881 gagagacacg gcgaaaacaa atcatgcaaa ccttggcaaa tacagaaaaa ccagtgagtg
    32941 ctagcaagtt tgcgaaaact tttggagtca gccgtcagat cattgtaggc gatattgctt
    33001 tactacgagc tgcaggtaaa agtatcgtgg caacagcaag aggttatatc ctcgaaacag
    33061 aagaaaccaa tactgggcac atcagtaaaa tcgctgtcca gcatggaaaa gatcaaacag
    33121 aagaagaact gagactaatc gttgaaaatg gtggtgaaat cattgatgta attgtggaac
    33181 atccccttta cggtgagtta gcaggaactt tgcacatcaa aacgccacaa gatatcgatt
    33241 cctttatgag acgttatcaa aaaagtaatg ctactttgtt atccgaatta acaggcggca
    33301 tccatctgca tacgatccgc tacccagaaa agcatatgct gaaaaacatc aaacaaaaac
    33361 tagctgaagc aggaatcctc tacgaaggat aacatcgtag ctgctacttt ttatcctaga
    33421 aactattcta tcatctctga gataaacacc catatggaag aaataagaaa aaataagaaa
    33481 agatgcgtat ccaatacaca gaattttttg gaattgcgat ttctagatgt ctatctaaat
    33541 ttcgattagt ggagaaacat aaaaaaggga agtgcagctt ttgagcactc ccctttttta
    33601 taaagctttc ttgtagcata gtatcgaagg aacctgccaa ttctctactc gatcaccaat
    33661 acgccttctt ttagtgcaaa tggattttga tcgttgatgt ggtcatagaa catcacaccg
    33721 ttgatatggt cgatttcatg ttgaacgacg atcgattcat aattcttcaa acgaatcttg
    33781 tgtttttcac cattcatatc ataataagac acagtgattt tggcatggcg aacaacatat
    33841 cctggtactt ctcgatcaac agataaacag ccttcacctt cccctaaaca agcatcttga
    33901 acagaatggc tcaaaatttt aggattatac ataacagtac ttagagaagg tccatctgcc
    33961 tctgggtcag gacttggtac gtgaacagca atgattcttt tagaaatatc taattgagga
    34021 gcagctaagc caacaccgcc tcgtaagtgt agttcttcag ctttgattgg atcttggctg
    34081 ttttttaaga actcaagcat ctcttttcct aaagagatat cttcttcgct taatggaaga
    34141 gaaacttctt ttgcaacttc gcgtaaggtc ggatttcctt cacgaatgat atcatccatt
    34201 gtaatcatgg aatatgtacc cctttcttaa aagactgtgt ttcaagtcta ttttcgcatt
    34261 atagtttacc acaaaaatgg aaaagtagta gtaagattgt ttgaaaacta ccttttctta
    34321 atgattaact acttgatttt caacccggtt tcaggtaaag tatagctgtg tgctctaggc
    34381 acatgacctg ccacttggtt aagcgaatca ccaacgtttt actcagtcgc aggggaataa
    34441 tcgaaagagg tgaaagaaat ggcaatttca aaagaacgca agaatgaaat catcaacgaa
    34501 tacgctcgcc atgaagggga tactggttct ccagaagtac aaatcgctgt attaactgaa
    34561 gaaatcaacc acttgaatga acatgcacgc gtgcacaaaa aagaccatca ttcataccgc
    34621 ggcctaatga aaaaagttgg tcaccgccgt aacttgttag cttacttacg taaaactgac
    34681 gttcaacgtt accgcgaatt gatcaaacgt ttaggcttgc gtcgttaatt ttagtcaaaa
    34741 agagtgggat tcacatgaat ctcacttttt ttactcgtat atcaattaag taaaattccg
    34801 tgatcaagct agatggactc ctactaacca aatgaaagct gctcaaaaga cggctttcgg
    34861 cagttttcat ttgtttagta gcgtcttgct ttcacgagaa ggaaaaggag aagttatgtc
    34921 agaaaaacaa gtattcaaaa cgacatgggg cggccgtccc ttacaaatcg aagtcggtca
    34981 gctagcaaaa caagcaaacg gagccgtttt agtccgttat ggagatacag tagtcttaag
    35041 tgcagctgtg gcctctaaag aagcaaaaga tacagacttt ttcccattaa cgatcaatta
    35101 tgaagaaaaa atgtatgcag cagggaaaat ccctggaggt ttcatcaaac gagaaggccg
    35161 tccaagtacg gaagcaacat tgactgcccg tttgatcgac cgtccaattc gcccgatgtt
    35221 tgcagaaggc ttccgtaatg aagtccaagt aacgaacatc gtgatgagtg tagaaacaga
    35281 ctgctcgcca gctatggcag caatgctagg ttcttcttta gcactatcaa tctcagatat
    35341 cccatttgac ggcccaatcg caggcgtaga agttggtcgt gtaaatggcg agtacgtctt
    35401 gaatccaaca gtagaacaag cagaacaaac agatatcgaa ttgactgttg ccggaacgaa
    35461 acaagccatc aatatggttg aaagcggcgc gaaagaagtt tcagaagaag acatgcttgg
    35521 tgcattgctg tttggttttg acgctatcaa agagttagtt gctttccaag aagaaatcgt
    35581 tcaagcagta gggaaagaaa aaatggaagt gactttactg caagttgatg aagtattgaa
    35641 aaaagaaatc tttgatgctt cttacgctac aatgaaagca gcagtaatga ctgaagaaaa
    35701 acttgctcgc gaagataata tcgagcaggt gaagatcgat atccgcgaag cttatgctga
    35761 gaaatttgca ggtcatgaag atgaagatca cttgttgaaa gaagttaaac aaatcacaga
    35821 agatcttgaa aaagatgtcg tacgtgaatt gatcaccatc gataagatcc gtcctgacgg
    35881 gcgtaaattg gatgaaatcc gtccattgtc atcagaggtc agcttattgc cacgtgtaca
    35941 tggatcaggt ttgttcacac gaggacaaac acaagcttta tcagcttgta cactcgcacc
    36001 tctaggagag caccaaatca ttgatggttt aggggtggaa gtcagcaaac gattcatcca
    36061 ccactacaat ttccctcaat tttctgttgg ttctacagga cgtgcaggct ctccagggcg
    36121 tcgggaaatc ggacatggcg cattaggtga acgtgcgtta gcacaagtaa tcccttcaga
    36181 agaagaattt ccttatacga tccgtttagt agcagaagta ttggaatcaa atggttcttc
    36241 ttcccaagca agtatctgtg ctggcacatt agcattgatg gatgcaggtg taccaatcaa
    36301 agcgccagtc gccggtattg cgatgggact tgtttctgat ggtgaaaact atacgatcct
    36361 aactgatatc caagggctgg aagatcatct tggcgatatg gactttaaag ttgccggtac
    36421 aaaagatggt atcactgctt tacagatgga tatcaagatt caaggaatca cagaacaaat
    36481 cctaactgaa gcattaactc aagcaaaaca agcacgtatg gaaatcttag aagaattgac
    36541 ttcaacgatt gctgctccac gtgaagaatt aagccaatat gcaccaaaaa tcgaaatgat
    36601 ccagatcgaa cctgctaaaa tcaaagatgt tatcggtaaa ggcggcgata cgatcaacgg
    36661 aatcatcgat gaaactggtg tgaaaatcga tatcgatcaa gatggaaaag taagtattgc
    36721 ttcagctgat gcagaaatga tcaaaaaagc tatcaagatc atcgaagatt tgaccaaaga
    36781 agtcaaagtt ggtgaagttt atctagggaa agttgtccgt atcgaaaaat tcggtgcatt
    36841 cgtcaacttg atcaaaggaa aagatggact tgtccatatt tcccaattag caaacgatcg
    36901 tgtcaataaa gtcgaagatg ttgttaaact aggtgatgag atccttgtga aagtaactga
    36961 aatcgataaa caaggacgcg taaatctgtc aagaaaagca atgttgaacg aagatggttc
    37021 aacgaaaaat gaagaaaaat aatttaattc ataggaataa tgtacttgtg atcgtgaagg
    37081 tgacaggggg acaataatta ttcgaaaaaa ggggactgtg acaaaagccg tgtcacagtc
    37141 cttttttttc gaataaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaag
    37201 ttaaaaacat taggagctgt ttttatttgg ctgttcttat tacttgatgc agaacagctt
    37261 ttttacaacc tctccaataa acgatgttca atcagctgtc cctcgatatt agctcaaaaa
    37321 acggcaaaat atgaggaact atttttccgt ttgtttctct aatactcagg tcaaaccgct
    37381 gatttcacaa cctctgattc acggtgttcc agaagcagct tctacggaaa taagctgaac
    37441 acttttgtta caacttcttt ttttctggag tttcttggcg catatttttg gagtccttct
    37501 gaataaagcg taaaataaaa gtgagaaata tggataaagg agggaaagga gatgctgaat
    37561 tttttatggt cgttatttat cggcggtata ttaggtttga tagctggcgc aattttagga
    37621 aaggaagtcc cgggaggcgt atctggaaat atcattatcg gttttttagg tagttggctc
    37681 ggcgaatttt tactaggacc actgggaccg gaactcggcg gtttttattt gataccagca
    37741 ttattgggtg caattttttg ccttgctctt tattcatttg tggcaagacg tatcagagaa
    37801 cgtccaaaga aagaataatt ttattcaaat aagttgacac ttcagtgtgt tacttggata
    37861 attagaagca atttaggaaa gcgggtgtca tggataagaa tatcatctat cattcaagct
    37921 tacctaaagg atatccatat aacaagaaat gagggaaaaa cgtggcaaca acgcacaata
    37981 ccaaaaagat atcaatgact ggcctgcttg tagcgatggg agtcgtctac ggagacatcg
    38041 ggacaagtcc gctttacgtt atgaaatcga ttgttgaaga taatggcgga ttgtcaggaa
    38101 tcaatcctga ttttgttatc ggatcagtct cattgatttt ttggacattg actctactga
    38161 caacaatcaa atatgtcgtg attgcattga atgcagataa ccatggtgaa ggtggaattt
    38221 tctcactcta cacacttgtc cgaaaaggtg ggaaatattt gatcattcct gcaatgatcg
    38281 gaggagctgc cttactagca gatggggtat tgacccctgc tgtgacggta acgactgcga
    38341 ttgaaggctt gcgaggaatt ccgcagtttt ttgaccggtt cggtaataac cagaacgtga
    38401 tcgtcattat cactttagtt attatttttg ttttattcat ggtccaacgc tttggtacag
    38461 atattgtcgg aaaagcattc ggaccaatca tgttcgcttg gtttactttt ttaggcgtaa
    38521 tgggattaat gaacttcagt caagactgga cagttatccg tgcactgaat ccttattatg
    38581 ctatccagct gctttttagt gcagataaca aattaggctt gttcattctt ggaaatattt
    38641 tcctggctac gacaggtgca gaggcgcttt attccgatct tggacatgtc ggcaaacgaa
    38701 atattcgtct gagctggcct tacgtcaaaa tttgtttggt tatcaattat tttgggcagg
    38761 ctgcgtggtt gttgaatgtt tatcaaaacc ctgaagcaca gcaaatcaag aacctgaatc
    38821 cattcttcca aatgatgcct caaagttgga tcgtgatcgg cgttgctttt gcaacagtcg
    38881 ctgcagtcat tgcttcgcaa gcattgatta caggttcgtt tacgctagtt tcagaagcaa
    38941 tcaagttgaa actgctgcct cggttaaaga tcatgtatcc tgggaacagt atcgggcaaa
    39001 tgtatatccc agcagtcaat ctgattttat ggatcgcctg ttctctagtg gttgtcacat
    39061 tccgaacgtc tcatcatatg gaagctgctt acggtctatc gatcactgtg acgatgttga
    39121 tgacaacagc actgctttac ttttatctta tccaaaatgg gcattctcgt tggcttgcat
    39181 atttagttac ctttttcttc ggtgcgatag aagtcgtttt ctttatctca agtgttgtca
    39241 aattcttccg aggcggtttt gtagccgttc tgattggttt gatcatctta gtcgtgatgt
    39301 ttatttggga acaagggaac attattcgcg aatcgtcaac cgaggatgtg tctttgagag
    39361 attatatccc gcagcttaga gaattacgtg atgatacttc tttaccaatc tatcagacaa
    39421 atgtggtctt cttggttcct gatatggctg aagataaagt tggccgacag ttcatctatt
    39481 cgattttaga taaacggcct aaaagagcac gagtctattg gtttgttcat gtggaagtga
    39541 cggatgagcc atatacgaaa gaatatcaag tagatatgat ggacactgat tttattgtcc
    39601 aagtgaatct gttcttaggt ttcagggtcc aacaggaaat caacgtatat gttcgccaag
    39661 tcatccatga tttgatgaaa caaggccgtt tgccaaaaca gccacaaaga tactctctga
    39721 caccagggcg agaagttggc gatttccaat ttgtcctgat tgatgaagta gtttccaatg
    39781 tgacaactct aggaaaatgg caacgtcaaa tcatgcaggc aaaactggca atcaaaaaaa
    39841 tcgctacctc gccagaaaca tggtttgggc tagagtacag cgaagtaaaa catgaaactg
    39901 ttccgcttat cattggaaat actcggaaaa catggttgaa agagcggttg tgaaagtagc
    39961 gctttgacct gaactaatgt cgaatgtcag ctacttgaac accgtttatc agaggtcatg
    40021 aaaaagctgt actgcaacaa gcagtaagaa cgagcagata aaaacagctt ctcatgtttt
    40081 tcatctgttt gggcttaatg ccgtagatgc aagcttttga ataccgtttt tatcagaggt
    40141 catgaaaaag ctgtttagca acaagtaacg caatgatttt gaagtgataa ggagatgtgg
    40201 ctgaaaaatg ccgcatctcc ttttttattc ctaaatatga atacgcatta ttttcaatct
    40261 ttttgtagaa aaagggtaca atagaaaaag agaaaggcgg gagaatatgg ttatcaattt
    40321 cattatttta tttttgatga ttgcaattac ttcatttttt gtagcaagtg aatttgcttt
    40381 agtgaaaatc agacgatcaa gattggaaca actagaaaag gaaaatgtaa agaacgccaa
    40441 gctagctctt catgttacac accatttaga taactattta tcagctagtc aattaggaat
    40501 tacgctaacc ggtttgatca tcgggtgggt cggtgaagga tctgtcgcgg ctttactaga
    40561 accagtgatc ggtaaactac cttttagttc ggctattagc agtacaatct ctgtggcgct
    40621 gggatttatt ttagttacgt atatcgatgt ggttattggc gaactgcttc ctaagagcta
    40681 tagtatcgtc aatacggaga aggtcgtctt gttcgtagtt aaaccacttc attattttta
    40741 taaagtaatg tttcctttta tttgggtatt gaatcattca gctgcagggc tagggaagct
    40801 attaggtgtg cgtctcgtat ctgaaggaga agagacattg tctcaagaag agctgacatt
    40861 agtcgcattg aattcttatg aaaaaggaga gttgaccaaa gaagaatatt attatttgga
    40921 aaacgtgttt gaatttgatg ataccttggc aaaagatata caagtagacc gtacgtccat
    40981 gcaagtattc gaagcttcag aaaccgtcaa agaagcgata aaagcttcga ttgaacaagg
    41041 acatactcgc tatccggtta tcttagaatc aaaagacaat gttttaggtt atgtcacctt
    41101 gccagatttg atcaagcaat cttataaaga tgaccagctg acagtagaac agttgattga
    41161 agagccgatc gtaacaactg aaacgatccc tataaaaaaa ttattgacga tcatgcgaaa
    41221 aaagggtaag catattgcta tcttaaaaga tgaatacgga gggacaagcg gcttagtgac
    41281 gattgaagat attttagaag aaatcgtcgg ggaaatccga gatgagacag atttggacga
    41341 agcattgata gcggaacagt cagatggctc ttatatcatc tccggcaaac taacattaga
    41401 tgatttccag cgttattttc atgtagagat tccagagttt gaagaaacga attttactac
    41461 acttgcgggc tttgcttcta gccgatataa agaaataaaa gcaggaacaa tcattgagat
    41521 tgcatcattc cgtttcacgg tattagaata ccagcatgca catatcgatt atttcaaagt
    41581 agagtccacg gaaagaaaaa cagaataaaa gaaaaaaggc tgtgacattt tttgtcacag
    41641 cctttttgtt atctaaaaaa cctgttttcg gtaaacgaag aagatatttt caataaaagt
    41701 tttcattttt agccgcaacg atttctttta atcaaggcta tcttgcttct gcatgttcta
    41761 atgtgaaatg ttcctcttca cccatgtgtt tcaattgttt catcgaacgc atataagagt
    41821 aaagcaacac ggcaacagaa ccgatccaag ctaaaggaga agctgctgct gctcctgggt
    41881 atccccacat tcctgtaaga acgatagctg caaaagaacg cataagcaat tccatcatac
    41941 cggcgatcgt agggatcttg ctttgtccaa gcccttgaag tgtgtagcgt aaaatgaaca
    42001 ggactgctaa gatccagtaa agagacccat tgatattgaa gtaggtttgt gctaattcaa
    42061 atacacgtgt ttctgatggg ttaacaaaca attgaacaaa gaaatgaccg aagaaaatga
    42121 cgatagcacc tgctaagaga ctaaatccga cactcatcag taaagtttga cgtacccctt
    42181 gcaagattcg gccatattct ttcgcaccat agttttgtgc agtgaaagtt gccattgcaa
    42241 taccaaatga catcatcggc tgatttgcaa attggtcgat acgaccagca gcggcttgag
    42301 cagctacgac atctgtccct agactattta gtgctgcttg taacacgata gcaccaacag
    42361 cgatgatcga agattgaaac gccattggca aagcagcatt taggtgtaca gcaaactctt
    42421 ctttttcaaa tttgaaatct tttttgcgta actgtaacaa aggcattttt ttcttgatat
    42481 acactagaca cagtacgctg gaagaaactt gtgcgattac tgtagcaata gctgcacctt
    42541 ccacacccat gccaaaatag ataataaaga tcaaatcaag tacgacgttg atgatgaccg
    42601 caatgatcag aaagaatagt ggtgtgcggc tgtcaccaag tgcgcgaatg acattagaaa
    42661 gcaaattgaa actgactgat gcaaagatcc ctaataaaat aattgaaata aatgtttgtg
    42721 cttgatcaag tatttcagga ggagtttgca tcaattgaag catcggacga ataaacagga
    42781 gacttaggac agttaaaatc acagtgacga caagactaat gacaacacta gcagcaaaac
    42841 ttttcttcag accccgataa tcttttgcac cgtaacgttg tgcggtaata atggctaaac
    42901 cagctgttaa accttgggca aagccaatga tcaaaaatgt caggcttcca gttgcaccaa
    42961 ccgctgccag cgcattttta cctagcgtct gacccacgat gatcatatcg atcatattgt
    43021 agaactgctg aaaaacattt ccgatcagta aaggaacagt gaacatcaaa atcagtttag
    43081 cggggcttcc ttttgttaaa tcgcgcatct tttaaactcc ttatatcttt aaaatttagt
    43141 tagtagtata tagcgtttat cctgagaata ccaattagaa atcaatgata atttatgaaa
    43201 ctccataaaa agaagccaag aattgagtca aagaatcaac aacttggcct ggtctgtaaa
    43261 ataagggaca tccacgttta tctatcacct taatattgtc taatctcact tggtaaaagg
    43321 atcgtttctc tcgtaccgtc atcataggcg tatacttgag caggaaattg gttcgaatag
    43381 gcaaacggca aatcaatatc catttccaca ttgcttcctg cttgagaaaa atgcatcgtc
    43441 acttttccac gattttcgat caaatcaaag gttaatatat tttctaatgg aatgactccc
    43501 ttaagatcta ggtcaataat aaaccatata ctgtcaatca attcatctgg caaacttgat
    43561 acgacaccaa ctgaagcgta acggttgcgg ctgctatcaa aactttcaaa catctgttta
    43621 acctccttcg aatcaacgaa tgttttattt ttataattaa tcctaggata aactagaaat
    43681 acttacttca acgagggttc attctaataa agaatcagga aaaatgcaac aataattgaa
    43741 tacttttttt caaagtataa atttttataa aggtacgata aaagtatgcg aggaaaagct
    43801 tggtaaatta ggatttttcg tttgtaaagc catttacaaa agtggaagcc ccatatgaaa
    43861 ataaacgatt agaaataaaa aaggcgtgtt aaaagctgct gacccgccgc ttctaacacc
    43921 acctgattgt ttcagtatta ttcttctgtt gaaccgatca cttctggttc gccaccttca
    43981 cctgtgcttt cttcttcttc actttgagcg actacagcag cgatttgctc ttcactgtcg
    44041 gtcacgaatt tgtaatcgtc gttttttgga agatcggcta ctgtaataga atcacctaat
    44101 tccaagtttg tcacgtcaac ttcaattcgt tcaggcaatt tgtctggtgt agcagatacg
    44161 actactgtat acaagttttg agctaacact ccaccagatt tagcacccac tgattcgcca
    44221 acaagaacga cttctgtttc gacttctgtt tcttccgaca tgtttacaga tagaaattct
    44281 gcatgttcga aatgattggt aaaagtgttc gtttggatct tgtgaaccaa tgtattgact
    44341 ttttgtccat cgatgtccat cgtgatgact gtgttcgctc catgttcacg caacaatttg
    44401 cttagtgtca aaccatcgaa tgagataggg gtactttcta ctttataccc ataaacaaca
    44461 gctggaactt tcccttcgtg acgaagtttg tttcttaatg aacggggacg tacttctctt
    44521 ttacttactt ctaatgatac tgacataacc aaaattcctc cttaaaatgt gactgtctgc
    44581 tttggtaacg gacagatttt atttaagtga attctaaagg ctaatctcgt gcacatcatc
    44641 gaaggcaggg cgcttaaaaa agcgcaaaag gagagatgcg cgcatctccc cttagaaagt
    44701 caggattcaa cttttctcca ccaggtcatt acgctgtgta tgagaaatcc aattcacttt
    44761 actatttaac cgtaacgtga actgttaatt aagtcaagga ataactatga tgatgtattt
    44821 gcaagcaaga atattcaagg tataattaat tagtagtaat aagaaaggaa acagcatgcg
    44881 tttagataaa ttaatagaag aaaaattaga aacgacacgc aaggaaatga agcggctgtt
    44941 tgctttgaag caagtgatga tagatggcac agtcgaattt cgacaaaatc gaaatgtaga
    45001 tagtttactg catcaaatcg aagtagcagg tgaacactta gaaacaaatg agtcctatta
    45061 tcttctcaat aaacctgaaa aagctgttac agctgtatca gatccagaaa agacgacagt
    45121 aatcgatctg attgcaagtg ccgatcgttt ccaaccatta tatccagtgg gaagactaga
    45181 tagagataca acaggactat tgctgatcac ttcgaatgga caattgggat atgaaatgct
    45241 acttccagaa aaaaaggttt caaagactta tcaagtagtt gtgaacgaaa gggtgacacc
    45301 ggcagacgta acagcatttg aaaatggaat cgtattcgct gatgggtatc aatgtaagcc
    45361 ggctgattta aaaatactca aagcagacaa gcaccaaagt acggttttat tgacgatcca
    45421 agaaggaaaa ttccatcaag tcaaaaagat gttcttagcc caaggaaaga aagtgaccgc
    45481 attgaaacgg ctaagcatgg gaccattgga attagatgaa cagctaggag taggcgagta
    45541 tcgatcgttg acattagcag agatgaaaaa gttaagtatt tattttaaat aggaggtcaa
    45601 aaagatgaaa tataaaactt tattgtttga tgtagatgat acattgttag attttcaatt
    45661 aactgaagcc aatgctttaa gtgctttgtt tgcagaacaa ggaatcacat tgacaccaga
    45721 aatcgaaacc agctataagg ctttgaatca tcatttatgg caggagtttg aaaaaggcag
    45781 actatcacga gaagaaataa taggcagtcg ttttgggtta cttttccagc aatttgggaa
    45841 aacagtagat agtgatcaaa tggaaaaacg ctaccgccac tacttgaacc aaggtcatga
    45901 tcttgttcca ggaagtctag aaatcctgaa aaaggtccat ccgcatgctg atctttatat
    45961 tgtgacgaac ggtgtgtcgc acacgcaaca tcggcgatta acagatgcag gaatgcttga
    46021 ttacttcaag gatatctttg tctcagaagc tgtcggagcg caaaagccga tgaaagaatt
    46081 ttttgatcat gtcttttccc acattcctaa ttttgataaa aagcaaactg tgatcattgg
    46141 tgattctttg acttctgata tcaaaggagg aaatatggca gggatcgata cgatttggtt
    46201 caatagaaat aaattaccag aaatcgaaga aatccagcct acttatcgaa tcgattcatt
    46261 agaggaactt tattcattat tggaaattga aaaggattaa ttttcagaaa aatatagcat
    46321 tttcgtgttt tttcgctata atagattaga atgaaaaaac ggatacgaaa gaggttttag
    46381 tcaatgacaa aaagcaagcc aattatcatt ggtgtgacgg gtggatccgg aagcggaaag
    46441 acaagtgtca gccgtgcgat tttcaacaac ttcccggacc attccatcat gatgcttgaa
    46501 caagattctt attacaagga tcagagccat ttgagttttg aagaacgatt gaacacaaat
    46561 tacgatcacc catttgcctt tgataatgat ctgctgattc agcatgtagg cgacttactg
    46621 aactataaag ccattgaaaa acccgtgtat gactatgtag cgcatacaag aagtcaggca
    46681 acgatcattc aggaaccaaa agaagtgatc attctagaag gaatcctgat tttagaagac
    46741 gaacgtctgc gtgacttgat ggatatcaaa gtatacgtag atacagatga tgacattcgt
    46801 atcattcgtc gtatcaaacg ggatatggaa gaacggggac gcacattgga ctccgtgatc
    46861 gaacaatatt tgacagttgt taaaccgatg tatcatcaat ttatcgaacc aacgaagcgc
    46921 tatgcggata tcattgttcc agaaggcgga gaaaaccacg ttgctattga tttgattaca
    46981 acaaaagtag ctagtttctt aaaccataaa tagtgcgcag cgaaacagtt gaacggactg
    47041 cgaccgtttg aaaagcaagg attctgcttt ttgaacagtc accagccaac tgttttttta
    47101 tttataacaa gaggttgtga aaacagcatc ttgacctaag tattaaaaag aagaaacgga
    47161 aaatagctgt ttatatttta ccgttttttg agctaatacc gaaggtcagc tgattgagca
    47221 ccgtgaagta gaggttgtaa aaaagctgtc tttgcatcaa gcgataagag catccaaata
    47281 aaacagctcc tcacgttttt cgttgggttg ggcttattat cgtagatgca agcttttgaa
    47341 caccgtttaa cgagaggttg taacagaagt ggtcagatgc aataaataag aagaaactta
    47401 cgaaaattat ttctcgaatt tgtgtgagat ttcgacttat ttttttgaag aagctctttt
    47461 gtcgcacccc c
//
LOCUS       DAXLPY010000016        46219 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.016, whole genome shotgun sequence.
ACCESSION   DAXLPY010000016 DAXLPY010000000
VERSION     DAXLPY010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.016"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            160..840
                     /locus_tag="ACF3UF_000986"
     CDS             160..840
                     /locus_tag="ACF3UF_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFD3671133.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="ACF3UF_000987"
     CDS             930..1964
                     /locus_tag="ACF3UF_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFD3671134.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="ACF3UF_000988"
     CDS             1978..2313
                     /locus_tag="ACF3UF_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671135.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="ACF3UF_000989"
     CDS             2297..4777
                     /locus_tag="ACF3UF_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671136.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="ACF3UF_000990"
     CDS             4833..6392
                     /locus_tag="ACF3UF_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3671137.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="ACF3UF_000991"
     CDS             6389..7753
                     /locus_tag="ACF3UF_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFD3671138.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="ACF3UF_000992"
     CDS             7924..8994
                     /locus_tag="ACF3UF_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671139.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="ACF3UF_000993"
     CDS             9009..9677
                     /locus_tag="ACF3UF_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671140.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="ACF3UF_000994"
     CDS             9697..10275
                     /locus_tag="ACF3UF_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3671141.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="ACF3UF_000995"
     CDS             10676..11587
                     /locus_tag="ACF3UF_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFD3671142.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /gene="rnhC"
                     /locus_tag="ACF3UF_000996"
     CDS             complement(11965..12882)
                     /gene="rnhC"
                     /locus_tag="ACF3UF_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFD3671143.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="ACF3UF_000997"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="ACF3UF_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFD3671144.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="ACF3UF_000998"
     CDS             13579..14127
                     /locus_tag="ACF3UF_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFD3671145.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="ACF3UF_000999"
     CDS             14242..16602
                     /locus_tag="ACF3UF_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFD3671146.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="ACF3UF_001000"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="ACF3UF_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFD3671147.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="ACF3UF_001001"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="ACF3UF_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFD3671148.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="ACF3UF_001002"
     CDS             19108..20007
                     /locus_tag="ACF3UF_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671149.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="ACF3UF_001003"
     CDS             20000..21262
                     /locus_tag="ACF3UF_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671150.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="ACF3UF_001004"
     CDS             21423..23321
                     /locus_tag="ACF3UF_001004"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFD3671151.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="ACF3UF_001005"
     CDS             complement(23651..24370)
                     /locus_tag="ACF3UF_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFD3671152.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    24560..24607
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            24707..25039
                     /locus_tag="ACF3UF_001006"
     CDS             24707..25039
                     /locus_tag="ACF3UF_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671153.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25026..27029
                     /locus_tag="ACF3UF_001007"
     CDS             25026..27029
                     /locus_tag="ACF3UF_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFD3671154.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27048..27518
                     /locus_tag="ACF3UF_001008"
     CDS             27048..27518
                     /locus_tag="ACF3UF_001008"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFD3671155.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27539..28123
                     /locus_tag="ACF3UF_001009"
     CDS             27539..28123
                     /locus_tag="ACF3UF_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFD3671156.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28138..29124
                     /locus_tag="ACF3UF_001010"
     CDS             28138..29124
                     /locus_tag="ACF3UF_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFD3671157.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29114..29425
                     /locus_tag="ACF3UF_001011"
     CDS             29114..29425
                     /locus_tag="ACF3UF_001011"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFD3671158.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29447..31228
                     /locus_tag="ACF3UF_001012"
     CDS             29447..31228
                     /locus_tag="ACF3UF_001012"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFD3671159.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31221..32597
                     /locus_tag="ACF3UF_001013"
     CDS             31221..32597
                     /locus_tag="ACF3UF_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFD3671160.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32604..33239
                     /locus_tag="ACF3UF_001014"
     CDS             32604..33239
                     /locus_tag="ACF3UF_001014"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFD3671161.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33269..34624
                     /locus_tag="ACF3UF_001015"
     CDS             33269..34624
                     /locus_tag="ACF3UF_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFD3671162.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34816..36210)
                     /locus_tag="ACF3UF_001016"
     CDS             complement(34816..36210)
                     /locus_tag="ACF3UF_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFD3671163.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36302..37273
                     /locus_tag="ACF3UF_001017"
     CDS             36302..37273
                     /locus_tag="ACF3UF_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFD3671164.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37270..38052
                     /locus_tag="ACF3UF_001018"
     CDS             37270..38052
                     /locus_tag="ACF3UF_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFD3671165.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38221..38592)
                     /locus_tag="ACF3UF_001019"
     CDS             complement(38221..38592)
                     /locus_tag="ACF3UF_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3671166.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38726..39169
                     /locus_tag="ACF3UF_001020"
     CDS             38726..39169
                     /locus_tag="ACF3UF_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFD3671167.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="ACF3UF_001021"
     CDS             complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="ACF3UF_001021"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFD3671168.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40040..41407)
                     /locus_tag="ACF3UF_001022"
     CDS             complement(40040..41407)
                     /locus_tag="ACF3UF_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3671169.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41391..42221)
                     /locus_tag="ACF3UF_001023"
     CDS             complement(41391..42221)
                     /locus_tag="ACF3UF_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFD3671170.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42384..42821
                     /locus_tag="ACF3UF_001024"
     CDS             42384..42821
                     /locus_tag="ACF3UF_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFD3671171.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42897..43517
                     /gene="rpoE"
                     /locus_tag="ACF3UF_001025"
     CDS             42897..43517
                     /gene="rpoE"
                     /locus_tag="ACF3UF_001025"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFD3671172.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43706..44212
                     /locus_tag="ACF3UF_001026"
     CDS             43706..44212
                     /locus_tag="ACF3UF_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFD3671173.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44229..45128
                     /locus_tag="ACF3UF_001027"
     CDS             44229..45128
                     /locus_tag="ACF3UF_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFD3671174.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45215..46099
                     /locus_tag="ACF3UF_001028"
     CDS             45215..46099
                     /locus_tag="ACF3UF_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD3671175.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
BASE COUNT        15236 a         7977 c         9766 g        13240 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt
    24421 aaactatgta agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga
    24481 gaaatttcgt gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa
    24541 aagtaagcag aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg
    24601 agaaggacat tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt
    24661 tcaatgaaaa aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt
    24721 agaagctttg gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact
    24781 gcggcagcag ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac
    24841 aaactatcga caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga
    24901 attagaaaaa gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa
    24961 agatcaatat caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga
    25021 aacttatggc cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg
    25081 agaggatttt acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa
    25141 atagaacaaa caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag
    25201 aagcaaaatt aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca
    25261 tacaacacca cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct
    25321 tacaagattt ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc
    25381 ttgatttaaa agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg
    25441 aagaatggct tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga
    25501 cgaccatttt tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac
    25561 tgagtaagct tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc
    25621 tttcgtatgt tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg
    25681 ggttcaataa agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca
    25741 agcagcaatt atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt
    25801 gcagtggcta tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac
    25861 gagaaaaaat aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg
    25921 tagatgcaga agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag
    25981 atatatacgt cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta
    26041 aattgaaaaa ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc
    26101 caaaatatga agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg
    26161 ggatgatggt cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc
    26221 aaaaactact tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct
    26281 cgataccatc gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa
    26341 aagaactgtt tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata
    26401 cgattttgat tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg
    26461 cagcaaagga aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct
    26521 ggcaagggat cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata
    26581 cagcatttgt ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg
    26641 ttccgattat ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt
    26701 acggactgac cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta
    26761 tttcaggcgg aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg
    26821 ctcgattcag tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga
    26881 cactgctaag tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt
    26941 tttatacagg aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca
    27001 tcaatcacaa gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact
    27061 taattagtca aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt
    27121 tttcagggat cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga
    27181 caacaagtca acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc
    27241 aaggtttgta tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt
    27301 cagttgtaca aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt
    27361 tttcaggtat tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac
    27421 ctgaacatgc tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag
    27481 gtttcgttat ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat
    27541 gaacgccatt gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc
    27601 gttagaacaa gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt
    27661 tgaaacagaa catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg
    27721 tcagctaagg aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga
    27781 atttttaaga cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga
    27841 acaaatccag tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt
    27901 cattgctgga gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa
    27961 tgaacttccc tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct
    28021 gataaacgat caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca
    28081 aggaacgatg agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg
    28141 gaataccacg aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag
    28201 acatttgaac ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc
    28261 acgatttaca gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta
    28321 aaggagcaga gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt
    28381 tggatctata cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg
    28441 acaaatcaaa atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg
    28501 aaggatgcca ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata
    28561 cgagaagtac gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat
    28621 gatcgacagt ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg
    28681 ctgacagaag tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata
    28741 ttgcagaaaa gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa
    28801 aaagaagtat ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta
    28861 gagacagatt atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta
    28921 aagcttgaac agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag
    28981 gctttcggac cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac
    29041 cttcgtttac tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg
    29101 gtgagacaag tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc
    29161 attcaaattg tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc
    29221 aattgaagaa atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc
    29281 attgagccca gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat
    29341 tcccaatcat caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa
    29401 agcagtaggt caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa
    29461 aatcataaaa gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca
    29521 agacatgtgt ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga
    29581 tgtggcgtct attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg
    29641 ctctactggt gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga
    29701 cggaatccaa cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg
    29761 cggagttcaa ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga
    29821 agccggagaa acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat
    29881 aaaacataaa atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg
    29941 ttcattcact attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt
    30001 gacgatgctt caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc
    30061 ggatgcaccc atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg
    30121 aggagcagca gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat
    30181 tgcaaaatgg gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga
    30241 gatgacggat gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt
    30301 gatggaacgt acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc
    30361 ttctatctat acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc
    30421 tatcatggca gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt
    30481 ggaagaaatg cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata
    30541 ctatgaacga tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac
    30601 cgcaatcagt gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac
    30661 attgcgggtc gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt
    30721 tccttcgatc gattggatac aaagctattc tctttattca acagaagtag ggaagtatat
    30781 ggatcatatc cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca
    30841 ggaagaacag cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa
    30901 tgaccgtctg acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc
    30961 ttttgatgat gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat
    31021 cttgaccttt ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat
    31081 catggacggt accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac
    31141 agaattagaa aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt
    31201 ttcagaagga ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc
    31261 cattgatggc ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta
    31321 tgcaaaatgg cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg
    31381 tccaaatatt cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag
    31441 gccatccttt agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg
    31501 gacgaccgaa agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag
    31561 aagtaatcaa tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg
    31621 caatcgatca tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg
    31681 gtcttcctca taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat
    31741 cagatgattt cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt
    31801 tcatggaaga ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag
    31861 caaacgaccc tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat
    31921 atcttgctta tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg
    31981 cagaggcatt gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc
    32041 ctgggtatct ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac
    32101 taaaaggatc ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc
    32161 caatccctga cttgactggt tatattacag aaggacagat catcttgact agagagcttt
    32221 acaagagtgg gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata
    32281 agggaactgg acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg
    32341 cagcctatgc acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt
    32401 tatctgatgt agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca
    32461 atcaaggatt ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc
    32521 tatcgatgtt gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc
    32581 tgccagaagg gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat
    32641 tgactcgatt gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata
    32701 agcaagatga actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc
    32761 aagaaatgga agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga
    32821 tcacggaacc tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta
    32881 tcgtagacaa aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac
    32941 agctgacaga cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt
    33001 caatcgatcg gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa
    33061 cttgtcaact gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat
    33121 atatgacgat ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa
    33181 acgagcgcgc agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag
    33241 tggtatcttt ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg
    33301 tttgccggct gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg
    33361 cctacttacc ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct
    33421 tttcactgca acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca
    33481 ttggaacagt gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt
    33541 tatgatggtt ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg
    33601 tattatatta aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct
    33661 ttacatccta aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt
    33721 atttgtgcct gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc
    33781 tagtttttgt aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa
    33841 tgtttatttg atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt
    33901 atggcgtgat ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc
    33961 attaaccgtt acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg
    34021 caatggggca acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat
    34081 gagtgtgaca cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc
    34141 aggtctgatt ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg
    34201 cggattgaaa acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg
    34261 acgtacgaga gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact
    34321 tactttattt tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac
    34381 tgaaacgata cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt
    34441 tggtacagta ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat
    34501 cattatagcg cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat
    34561 gacaaaagca caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg
    34621 ataatttcat cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt
    34681 ttcttgcttc ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg
    34741 ttgttgaacc tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct
    34801 ttatttatca ataggttata attcatattt ttttattttt tcttttacga tacttagtcc
    34861 agaagctaaa atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg
    34921 cgcacgtgta gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt
    34981 ctcaattatc ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg
    35041 attcgttggt ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag
    35101 acttaattta gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac
    35161 ttccacatct aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct
    35221 ttggacatgt actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt
    35281 cattccagct aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt
    35341 atgttgatag taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc
    35401 tttttcaatc acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg
    35461 attattacaa gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat
    35521 caatatatca ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata
    35581 taactgagcc aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc
    35641 tggagagaaa agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga
    35701 tagagattct aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa
    35761 ttgaaaattt gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt
    35821 actagttgat tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag
    35881 accaaaatca atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac
    35941 attgggagaa ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc
    36001 atatttataa gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct
    36061 ttgggagggt aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg
    36121 ttgaatcaac gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa
    36181 cgggtaattg tcataagaat taataggcat tttctccact ccttaaaatt gtataccata
    36241 caattttacc attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc
    36301 tatgaaaatt attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca
    36361 agtaatgaaa aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt
    36421 ggtggaaatt ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt
    36481 gggggagaac agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta
    36541 tcatttacct tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa
    36601 agcattgata aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc
    36661 aacagattac ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca
    36721 agcattgtcg catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta
    36781 cgatatttta gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa
    36841 aataacgttt ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg
    36901 tacgttgacc tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca
    36961 tatcaatgct gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga
    37021 aacttctcaa atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct
    37081 tatagccatg gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt
    37141 agtttctgag aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt
    37201 tggtctagct attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg
    37261 ggctttaaaa tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa
    37321 ggaaatccag cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa
    37381 attgccattg aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt
    37441 gagcttagat ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca
    37501 acagcatttg ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact
    37561 caaagcggta atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt
    37621 attatgccga aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt
    37681 aaagaagcct acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct
    37741 aaattgcagc cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg
    37801 acagcagaaa gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc
    37861 aatgaagatc cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga
    37921 atgaataaaa caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt
    37981 gaattaaaag aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc
    38041 tcgtttattt gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta
    38101 tagctacaat ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt
    38161 ctcattttaa ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa
    38221 ctatcctcgg atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg
    38281 cgcagtgcca ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc
    38341 gtgtaatttt tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc
    38401 atacgcacca tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt
    38461 caaataaaca agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc
    38521 aaatgccttt tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg
    38581 agccattttc atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta
    38641 aggaaatagt tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat
    38701 aaaactgtta aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt
    38761 tgctgattat caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc
    38821 agtaatcgag gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga
    38881 gacgaaagaa gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat
    38941 ttcttcttat ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta
    39001 ttataatcca ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga
    39061 aaagaccaat aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg
    39121 tagccaccga tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag
    39181 tagatcagct ttctctcagt ttttttattt attacagtac atattttttg attgcttcag
    39241 ctacaccgtg ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa
    39301 cggcatttcc cattgctact cctagaccag catattcaat catggataag tcgttctcgt
    39361 tatctccgat agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa
    39421 ctgccgcacc tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga
    39481 ccgttgtgta tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt
    39541 ctggttcgtc gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg
    39601 ttcgatattt tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat
    39661 ctcgattagg cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc
    39721 gtgccattac ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt
    39781 tacctgattt cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt
    39841 gaaaaaggtt caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata
    39901 aaacgatcga aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta
    39961 cttctctttt ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca
    40021 taatttcctc caatatattt taatttattt caatcaatgc gccattacgg atatggctgg
    40081 caaattcttg ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca
    40141 tttcttttgg aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa
    40201 gctgactaac ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg
    40261 tgcgatgtct gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca
    40321 cagcagtgta ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga
    40381 ctaattttga atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa
    40441 aacgtttagc taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag
    40501 tgcccaagac cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa
    40561 atggcagaag taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt
    40621 gtgcgcgatg aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt
    40681 acacttgcac atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac
    40741 tcatggaaaa agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat
    40801 caaatgttcc atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat
    40861 ctgcatcgat ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga
    40921 tcacactagc taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt
    40981 ctgtttctgg agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat
    41041 gttcaaatgt atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag
    41101 tcaccagccg ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc
    41161 gagaaaagat atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac
    41221 ggctatgttc tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta
    41281 gacgttggac ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat
    41341 agttatggac tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg
    41401 ttgtcataat gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc
    41461 cattgctcca gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca
    41521 gaatacagct tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt
    41581 tggtcaagca gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt
    41641 gtaccaaagt cttcttttaa agcagattga taaaatcgct tcatgacttg cccacgtttt
    41701 tcctgattac cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc
    41761 tgagcgatac cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa
    41821 gaatgggtga tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg
    41881 agcatttgct cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc
    41941 aaagaaatat tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc
    42001 actggagcgt aacctgcatc ttccagtgtt tggatcccgt cacttagaaa aggagttcga
    42061 acatccttca tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc
    42121 tggtgttctt tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt
    42181 ttttgataaa tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat
    42241 aaattcatat tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt
    42301 tttctgtaaa aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta
    42361 tgagaagtaa aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat
    42421 tgcgtacaaa agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc
    42481 aaatggtgac aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg
    42541 gcgatgagat tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg
    42601 caggagaaat gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc
    42661 gaacaccata cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga
    42721 aagaccgtcc cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa
    42781 aaatcggcga atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga
    42841 ttttttgtgt ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg
    42901 aaattagtgt atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg
    42961 cgatcttaga acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa
    43021 actatcttgg gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact
    43081 tgaatattga cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt
    43141 atgctatcga ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata
    43201 ctccacgtcg ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga
    43261 tcgattacaa tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc
    43321 tgtttgatga cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag
    43381 aaatcggagc agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag
    43441 atttaagtat catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg
    43501 actctgaaaa agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct
    43561 atcagaataa ggaggtgtga cacgattttt gtcacacctt cttttttgta tataaaaatc
    43621 ccaagtaaat acataaaaaa taaaaaaatt gaaactttta gcgcaccttg tacgtcatat
    43681 taagtgaggc agaaaggagt ggagaatgat ttttactgga tataagaaaa aacggcagat
    43741 cgaaaaatac cgtcacctgc tgaatggact catcgaaact gattatcaaa aaatgttccg
    43801 tatcacgatg aattacgtac atgataaaga agaggcctta gatgtgatgc aagatagttt
    43861 tcataaagcc ctgaactatt ttgaaaaaga aaaagagatc gagcatttta gtgcatggtt
    43921 ttatcggata ttgatccgca cggcattaga tagttggcgc agacaaaaaa ggacgcctgt
    43981 ggacttattt gaaattcaag atatccccca acagttacct ttagaaactt ccgttgcaga
    44041 gctccatatg attttagata aaatagacag tccggaaaaa gagattctga tcctctactt
    44101 ttttgaagga tttcgtttga aagaaattgc gactatcttg gatatgaatg aaaacacagt
    44161 taaaacgaaa atgtaccgct cattgaatgc tttacgtcaa atcctagaat gaaggagaga
    44221 agagtgccat gtattcccaa aaagaaaatt taaaaaaact aaagaaaact tataaagaac
    44281 aagcaattcc caaagggctt aaagaggaga tccgccagcg ttttattatc gaagagcaat
    44341 catttataaa agcaaagcgg agaaagagac gtctccaagg gttcggagta tctttggcta
    44401 tcgtaatgat tacaacaagt agccttcttt ttaatagtca agttcgaagc tttgcagaag
    44461 atttacccat cttaggatca gtcattgaat tgatcttagg cgaacgcttt actgatcgat
    44521 ctgaaaaaat cgatattcag gtaccgaaga tcaatacaca aaatgagaaa gaaaataaaa
    44581 caattcatgg attaaatcaa aaatactttc gcgaaggaca agcagatttt gaaaaagctg
    44641 aaaaagaata tggaaatttt gaaacggatc attaccaagt tttgggagat tatcagaaaa
    44701 tcgtagacga taaccggttt ctcgtgattg aaaggcagat cacccaaaca gcagcagata
    44761 gccatgttga aaaaagatac gacacaatcg acaagaaaaa cagtgtccag ctctcacttc
    44821 cacttttatt caaagatgac acctatctat ctgttttgac aaaagaagtc aaacggcaga
    44881 tggccgaaca agtcaaggaa gatccatcta agtactattg gactgagcaa gatattcaag
    44941 aagggacgat agaaaaacca acacttgtta cgcctacacg aagtttttat ttgaacaaag
    45001 agcatcaatt agttttgact ttttctcaat acgaaattgc tcctggttat atgggtacac
    45061 cagaatttgt cattcctaag tccgtgacaa aaacgatttt ggcatcggaa gattatttgg
    45121 atcattagac gagaagtagt tgcgactagc agtttcaatt ttcaagtaag tacaagtaaa
    45181 taataagaag agaaaaagag aaagaagaga tatagtgaaa agaaattatt tagttatcag
    45241 tattattgct ttatccgtgc ttttgttttt cgaaattact tcggtggcct ccttgatcac
    45301 cgaagtaaaa ggacaaacac actcttcgga gcattcgtca caatctttca aacaatcaga
    45361 acaatcaacc attaaaagcc aatcaactga aacagctaac gtcaaagaag ccattcaaga
    45421 atcagcggaa aaggtacaaa gtcagtcatc acaatcaaca caagacagta caaaaacgag
    45481 ccgagatccg gctgtcaaaa gcgtcgcaat cagctttgat gatggaccag gagcgaccac
    45541 aacaccgcag cttctgcgaa tcttaaaaga aaaaaacgtg catgccactt ttttcgtctt
    45601 aggagaaaat acggcgcagc atcctgaaat cgtgaagcag acagctgaag cagggcacga
    45661 gattggcaat cacacatacg atcatcagaa tctggccact ctttctgccc agtcgatgac
    45721 ggaggaagtg acgaaagcag acactgagat caaaaaagtc actggcaaaa cccccacttt
    45781 tgttcgtccg ccctatggtt ctgtcacgaa tgtaggagca acgatcatcc agcgaccgat
    45841 catcgaatgg tctgttgatt cagaagattg gaagacaaga aatcctgatt tgattttgca
    45901 gaagatccaa gcaacagtat acgatggggc aattatttta ttccatgata tctatcctga
    45961 aacgattcgt gccgttcctc aagtgatcga ttatctgaaa gagcaagggt atcgcatcac
    46021 gacagttggg gatttattag ggcatccaac ggctgtcgag aactattatg gcagaaacga
    46081 tcatcggcca gttcagtaag tgagacaagt atctttaata aataacacat tttaataagt
    46141 agttgaacac ataactacct tacttgcaaa ggcttaacaa tatctataca ggtacaacaa
    46201 aaaactgtcc accaatttt
//
LOCUS       DAXLPY010000017        43500 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.017, whole genome shotgun sequence.
ACCESSION   DAXLPY010000017 DAXLPY010000000
VERSION     DAXLPY010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.017"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(140..2521)
                     /locus_tag="ACF3UF_001029"
     CDS             complement(140..2521)
                     /locus_tag="ACF3UF_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFD3671176.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2511..3158)
                     /gene="recU"
                     /locus_tag="ACF3UF_001030"
     CDS             complement(2511..3158)
                     /gene="recU"
                     /locus_tag="ACF3UF_001030"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFD3671177.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3222..3761
                     /locus_tag="ACF3UF_001031"
     CDS             3222..3761
                     /locus_tag="ACF3UF_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFD3671178.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            3851..4270
                     /gene="gpsB"
                     /locus_tag="ACF3UF_001032"
     CDS             3851..4270
                     /gene="gpsB"
                     /locus_tag="ACF3UF_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFD3671179.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4292..4659
                     /gene="rnpB"
                     /locus_tag="ACF3UF_001033"
     ncRNA           4292..4659
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACF3UF_001033"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4868..6034
                     /locus_tag="ACF3UF_001034"
     CDS             4868..6034
                     /locus_tag="ACF3UF_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFD3671180.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6080..7576
                     /locus_tag="ACF3UF_001035"
     CDS             6080..7576
                     /locus_tag="ACF3UF_001035"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFD3671181.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYGIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7657..8340
                     /locus_tag="ACF3UF_001036"
     CDS             7657..8340
                     /locus_tag="ACF3UF_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3671182.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            8985..10175
                     /locus_tag="ACF3UF_001037"
     CDS             8985..10175
                     /locus_tag="ACF3UF_001037"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFD3671183.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            10277..11230
                     /locus_tag="ACF3UF_001038"
     CDS             10277..11230
                     /locus_tag="ACF3UF_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFD3671184.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            11299..12648
                     /locus_tag="ACF3UF_001039"
     CDS             11299..12648
                     /locus_tag="ACF3UF_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3671185.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(12831..13154)
                     /locus_tag="ACF3UF_001040"
     CDS             complement(12831..13154)
                     /locus_tag="ACF3UF_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671186.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            13283..14446
                     /locus_tag="ACF3UF_001041"
     CDS             13283..14446
                     /locus_tag="ACF3UF_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3671187.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            14516..15865
                     /locus_tag="ACF3UF_001042"
     CDS             14516..15865
                     /locus_tag="ACF3UF_001042"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD3671188.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(15910..16341)
                     /locus_tag="ACF3UF_001043"
     CDS             complement(15910..16341)
                     /locus_tag="ACF3UF_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3671189.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            16729..19371
                     /gene="alaS"
                     /locus_tag="ACF3UF_001044"
     CDS             16729..19371
                     /gene="alaS"
                     /locus_tag="ACF3UF_001044"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFD3671190.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            19571..20167
                     /locus_tag="ACF3UF_001045"
     CDS             19571..20167
                     /locus_tag="ACF3UF_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3671191.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            20289..21437
                     /locus_tag="ACF3UF_001046"
     CDS             20289..21437
                     /locus_tag="ACF3UF_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFD3671192.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(21475..21888)
                     /locus_tag="ACF3UF_001047"
     CDS             complement(21475..21888)
                     /locus_tag="ACF3UF_001047"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFD3671193.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            21967..22398
                     /locus_tag="ACF3UF_001048"
     CDS             21967..22398
                     /locus_tag="ACF3UF_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFD3671194.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(22497..22730)
                     /locus_tag="ACF3UF_001049"
     CDS             complement(22497..22730)
                     /locus_tag="ACF3UF_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3671195.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            22913..24583
                     /locus_tag="ACF3UF_001050"
     CDS             22913..24583
                     /locus_tag="ACF3UF_001050"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFD3671196.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            24730..25116
                     /locus_tag="ACF3UF_001051"
     CDS             24730..25116
                     /locus_tag="ACF3UF_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671197.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            25103..25801
                     /locus_tag="ACF3UF_001052"
     CDS             25103..25801
                     /locus_tag="ACF3UF_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFD3671198.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            25806..26270
                     /gene="lspA"
                     /locus_tag="ACF3UF_001053"
     CDS             25806..26270
                     /gene="lspA"
                     /locus_tag="ACF3UF_001053"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFD3671199.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            26267..27178
                     /locus_tag="ACF3UF_001054"
     CDS             26267..27178
                     /locus_tag="ACF3UF_001054"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD3671200.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            27413..27952
                     /gene="pyrR"
                     /locus_tag="ACF3UF_001055"
     CDS             27413..27952
                     /gene="pyrR"
                     /locus_tag="ACF3UF_001055"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFD3671201.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            27966..29249
                     /locus_tag="ACF3UF_001056"
     CDS             27966..29249
                     /locus_tag="ACF3UF_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFD3671202.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            29262..30188
                     /locus_tag="ACF3UF_001057"
     CDS             29262..30188
                     /locus_tag="ACF3UF_001057"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFD3671203.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            30207..31487
                     /locus_tag="ACF3UF_001058"
     CDS             30207..31487
                     /locus_tag="ACF3UF_001058"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFD3671204.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            31492..32568
                     /locus_tag="ACF3UF_001059"
     CDS             31492..32568
                     /locus_tag="ACF3UF_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFD3671205.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            32573..35758
                     /gene="carB"
                     /locus_tag="ACF3UF_001060"
     CDS             32573..35758
                     /gene="carB"
                     /locus_tag="ACF3UF_001060"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFD3671206.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            35812..36588
                     /locus_tag="ACF3UF_001061"
     CDS             35812..36588
                     /locus_tag="ACF3UF_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFD3671207.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            36585..37517
                     /locus_tag="ACF3UF_001062"
     CDS             36585..37517
                     /locus_tag="ACF3UF_001062"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFD3671208.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            37514..38230
                     /gene="pyrF"
                     /locus_tag="ACF3UF_001063"
     CDS             37514..38230
                     /gene="pyrF"
                     /locus_tag="ACF3UF_001063"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFD3671209.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            38237..38866
                     /gene="pyrE"
                     /locus_tag="ACF3UF_001064"
     CDS             38237..38866
                     /gene="pyrE"
                     /locus_tag="ACF3UF_001064"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFD3671210.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            38854..39168
                     /locus_tag="ACF3UF_001065"
     CDS             38854..39168
                     /locus_tag="ACF3UF_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671211.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            39206..39847
                     /locus_tag="ACF3UF_001066"
     CDS             39206..39847
                     /locus_tag="ACF3UF_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFD3671212.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            39890..40582
                     /locus_tag="ACF3UF_001067"
     CDS             39890..40582
                     /locus_tag="ACF3UF_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFD3671213.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            40579..41481
                     /locus_tag="ACF3UF_001068"
     CDS             40579..41481
                     /locus_tag="ACF3UF_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3671214.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(41639..43345)
                     /gene="efbA"
                     /locus_tag="ACF3UF_001069"
     CDS             complement(41639..43345)
                     /gene="efbA"
                     /locus_tag="ACF3UF_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFD3671215.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        13918 a         7681 c         9462 g        12439 t
ORIGIN      
        1 atgttagatc acacatgtat atgctggata gtcttataaa aaatcatgta atacagcttg
       61 gtacatgatt tttatttgta gctgtttttt acatagacac aaaaaagaaa ccacgcttgt
      121 agacgtggtt tcttttttac tatctgtttc cagaagctga ggtgctgctg gatggtgtat
      181 ggtcatttgc agcatccgct ccgctagttg ctggctcact ggaagaagca ggaggagcag
      241 atgaagacgg tgtcgagctt tcttcggatg aagaagaagg aaccgttgtt gaagacgctg
      301 gctcgcttgt ttctgctgtc gtgctttctt ttgaggactc agcagttgat tcgctttgac
      361 tagtagagct agagctttga gtcgttgtct ctgttgttga gcttccagga gtctggacat
      421 agctggaaga tggaatagtt gttgatggtg taattgcatt cgatctagct gtatattgat
      481 ctttgtagta cagttcaccg cccacacgaa ttaatccgct tggcatctcc cagtctgtat
      541 ttgtcacgtt agctgaaaca tactgcataa gctcgcgata aacatcagag gctacgtgtg
      601 acgattctga agtgacaggt gtcatttttt tattgtaacc tgtccacacg gaaatcgaat
      661 aatttggcgt atagcccgca aataggatat ctggatacac cccagaagaa ataccaagtt
      721 ttgcatactc gtcatctgtg taattggatg ttccggtctt accggcttga tataacccag
      781 cgatttgcgc attcgtacca gttccttcag tgatcgtatc ttttaaaatg tctgtgatca
      841 tataagctgt ttctggagac atggctgttt ttccatctgg ctcataagtt tcttctgttc
      901 cgtcttggaa gacgatttta ttaacatatt gaggtttgta ataagtccct ccattggcga
      961 aagccgcata ggctgctgcc atttttaagg aagaagctcc gtattttgtc ccatcttgtt
     1021 cttccgtatt actagagatc gcattcgatt gatggatcgt actgtattcg atcccaagat
     1081 tttttaagaa agaagccact ttatctgaac cgacttcatt gaataatttg actgctggaa
     1141 cattacggga taagtaaagt gcttggcgta aagtaatggt gcccatatat tgattatccc
     1201 agtttcctac aggagtcgaa gtcccttcat agttatacgg tgcgtcagta atagtttttc
     1261 cagtagaata tttcaaatat tcaaaagctg gtccgtaatc tgtgacaggt ttcatcgtag
     1321 aaccaaaatc acgggaagta ttcactgcta agttgttgcc taaagttacg tcttctgcga
     1381 tgtgacgtcc gccaatctgg gcttttactt tcccggtatt ggtgtcgata agggtggagg
     1441 caacttgcat ctcgtcgtct gggtaagaga catactgatc cgtgttgacg atatcatata
     1501 gtttcttttg ggcgtccaga tccaaattcg tataaatctc taaaccgtct gtgtagacat
     1561 tcttatctgt tttttcttgt acttcattga tgacttcttt gacataatta tcgacgatct
     1621 tagtattgtc atcggattga gttagttctt gcagaccatc cgttaccggt acattaacag
     1681 cttgatcata ttctgtttga gagatttttt cgttttgaag catcgtatac aaaacagtat
     1741 ctcgtctttt cttcgcctga tctggataaa cataaggatc ataggcggaa ggggcttgag
     1801 gcatcccagc aagcaatgct gtttgcggta aagaaagttc tgataatttc ttaccaaagt
     1861 acatctcaga agctgtctcc atcccgtaca agccgtttga catatacact ttatttacgt
     1921 agtaggtcaa gatctcttgt ttcgattttt tttgttccaa tcttacagcc atccacgctt
     1981 cttgggcctt gcgtttcaga gtctgatcct cggcactggt ggagaagaag gaaagtttga
     2041 tcaattgctg tgtcaaagta cttccgcctt gcagtccgcc agaggtaaag ttagagaggg
     2101 cagaaccgat gatccgaata gggtcaaccc cgatgtgttt ataaaaacgg cgatcttcta
     2161 ccgacacgat cgcatcttct aatgttttcg gtaattcatt cgcagaaatt ttttcacgct
     2221 tttctgcgcc taaatcttcg aatagttcgc catcttgtgt atatagtttg gaagatacgg
     2281 tagcgtctaa ttttttatcc gtcaattcgg gcgcatcttt tgcgtaatac cagaaaagtc
     2341 ctacacctgc taaaaagagg atacagaaaa atgagagtat tcctaaaagg atcttgataa
     2401 ataatccttt tttatgtgtt ccagaggact ttccagaacc tttgccagaa ttcttcttca
     2461 cactcttttt aggagtaggc tgtttctgtc gtctagagct tctagtttgt tcatttgcca
     2521 ttcttgcttt ctccttcaat agataatgtt gataaataga agtcaaccgc gtccaaataa
     2581 ggaatccgcg gagaaatacc agttttgatc tctattccta gttcttcgat caaagataaa
     2641 ggtagtgatt tgcgtccttt ttccttttgg gcgtcccagt aagcaatcaa atgaacacta
     2701 ttcaaataaa aacagcgctt caaagacgaa aaccataaca agacaaagca gaccccattt
     2761 tgttcgaggc atgctttcat atgttcgatt tgatgggcat ggaagttttt aaagggaaaa
     2821 gatgttttgt tcttggtttc ttttgcttca aagtccaagt aaaagcctcg atagacgcca
     2881 ttatagtctg tagttgaggc ttgggtaaag taggcttcct tgatcacagc agcacttctc
     2941 ttaggatagt ctactttcac gatttggata ggggtaggct ttttatggat aaccgccaac
     3001 ccgcgggaaa gataatattt attactttca ttgattgctt cttcaaagcg catcccccga
     3061 ttgccgaatt cagtgatctg atttcttttt tcttgaattt tttcgacggg agaggcattc
     3121 ttataataag gttggccatt tggatagcgc aataccatct ttaatcacac tcctaggcca
     3181 cattatagca aaaaagcgga tagaaagaaa aggaatctga gatggataag tcaaaagtaa
     3241 tctatgtgtc tgggtatcga agtttcgaac tcggtgtttt taaagaaaat gatcctaaaa
     3301 tccaagttgt taaaaatgtt ttaaaaaaag aactccatca gttagcagaa gaagggctgg
     3361 aatgggtact tgtcagtggg aatttgggcg tcgaactatg ggctgtgcaa atagtagcgg
     3421 aattgaaaga agaatatccg gaactatctc ttggtatttt gtatcctttt tctgattttg
     3481 gtaataactg gaatgaaggg aaccaagaaa aaaaacaatt agcagaacaa ttagcagatt
     3541 atgtcgaagc tgttagccat caaccctacc aatcacctag tcagctaaag aatcacactc
     3601 gttttatact tgagcataca gtgggctgtc tgctgatcta tgatgaagaa ttccctggaa
     3661 aaacgaagta tttttttgaa gatgcacaga attaccaagc agatcatccc tacgaaattc
     3721 ggctgatcag tatggacgat cttcaaaatt ttagtgaata atcgatattg tgtttgattt
     3781 atcaactttt ttcctataca atgaaaaagg tagaaatgtt attacgtaaa tgaaaactag
     3841 aggtgtaaat atggcgaatt tggtttatag tcctaaagac attttacaac aagaattcaa
     3901 aacaaaaatg cgcggctatg atcccgttga agttgatgaa ttcttagaca atatcatcaa
     3961 agattatgaa acttacagca aagaactcct tgctttacaa gaagaaaacg atcgattgag
     4021 tgcaaaagta gctcaattat ctaaaactca aggagcagct caaacacgcg tgcaacaaac
     4081 agaggcacca aagagcgcag cagtgaccaa ttttgatatc ttaaaacgct tgtcaaatct
     4141 tgaacgtgaa gtatttggta aaaagcttga tcaacaagca agtgcagtca aaccagcaca
     4201 acctaatcca aataactaca caaatgcaga cacaagctta gatgataatg aaaaaacacg
     4261 tcaattttaa tttttgatta atgaatttgc ggttttcggg taatcgcggt ctgacttgat
     4321 caggctgagg aaagtccatg ctcgcacagg ctgtgatgcc tgtagtgttc gtgcttagcg
     4381 aaaccataag ctaaggtact ctttggagta acggcaggaa aacaagctaa ggcttcggct
     4441 atgcttaagt atccttgaaa gtgccacagt gacgaagcgg ctggggaaac ccatccggtg
     4501 gaacgcggta aacccctcga gcgagcaacc caaacaatgg taggggcgct ttttgtctgg
     4561 aagaagaaca ggacaaaaag gcagtataac tgcagataga tggttaccgc tttgtttttt
     4621 ctccctggaa aagcaaagta cagaacatgg cttatagaaa accgcaaaca tcagggaatt
     4681 aggtcgtgac aaaagtaatg cgttataaga aacaagaaaa acatttgaaa gctatttttc
     4741 aatacttcag atgaatcgtt cttattacaa aacaaacttt tgtatcaccg gttattcgga
     4801 atttgagtaa aagtgtgggg taggactgat gtcccacctc ctttttttat aaataaggag
     4861 attgtgtatg gaaaaaaaca ggaagttcaa cctcgtcgca actgcggcaa gcgggctaga
     4921 agcactggtt ggtaaagaat taagagatct tggaatcgaa tgccaagttg agaacggacg
     4981 tgcacgtttt gaaggaacaa tggaaacgat cgctacagct aatttatggt tacgtacagc
     5041 agatcgagta aaaatcgtgg ttggggaatt cgatgcgtat acgtttgatg aattgtttga
     5101 aaacgtaaaa gcattgcctt gggaagattt tcttccacta gatgcagctt ttcctgtagc
     5161 tggaaaatcg atcaagtcga aactatatag cacacctgat tgccaagcga tcacaaaaaa
     5221 agcaatcgtt gaacgtctcc gtacctatta tcaccgtcca gcttctgtac cactgacgga
     5281 aactggcgca cattttcagt tggaagtagc tttgctgaaa gaccatgtga tggtaactct
     5341 ggatacgaca ggaccaagtt tattcaaacg tggttatcgc ttagaaaaag gtggagcacc
     5401 attgaaagaa aacatggcag cagcacttat tatgttgaca aattggcgaa aagaccgtcc
     5461 attttatgat cctgtatgtg gttcaggtac gctttgtatt gaagcagcct taataggcca
     5521 taatatcgca ccaggattca atcgtgagtt tgcttgcgaa tcttgggatt ggttcagtca
     5581 agaaatcatg gaaaatgttc gatcagcagc cgaagaaaaa gcagattatg atattgaatt
     5641 agatattact ggttcagata tcaatggacg gatgattgaa attgccaaag ccaatgcaga
     5701 agaaatcgga ttaggctctt cgattacctt taagcaacaa gcagtcaaag acttcaaaac
     5761 ggataaagaa tacggggtca tcgtggctaa tccgccttac ggagaacgtc taggagaaga
     5821 agaaactgtt cggaaattat ataaagaaat gggcgatgta ttccgtccat taaaaacatg
     5881 gagtaaatat atcttgacta gcgacttagc gtttgaggaa ttttacggac aaaaagcaac
     5941 caaaaaaaga aaattgtaca atggtgcatt gcgtacggat ctattccagt attggggaac
     6001 tcgtccgcct agaaaaaaag agaaagacga ataatcttac taattgattc attcaattgg
     6061 atgtttggag gaatagggaa tgaaagaaaa agagttttta caagaagtaa aagaaatcaa
     6121 tcttctacaa caagctttag gaatcctcga ttgggataca caaacaggta tgcctgaaaa
     6181 agctagtgca taccgaagtg aagtagacag ctatctttac ggcatttatt tttcaaaaaa
     6241 aatcggtcca aaaatcaaag aagccattcg ctatttttct gaacatccgg aagaattgtc
     6301 ggaagttgga actgccgttt ttgccaaagt aaaagaagag tatgatttgg aacatcgcgt
     6361 accggaagat cttatgagaa aatatacagc tgccgtttct tcagcacacg gacaatggca
     6421 aaaagctaga gaaacacaac aattttctga ttttcaacac gcattgaatc aaaatattga
     6481 attaacaaaa cagttgatac cttactggag aaaagatgaa aagacgaatt atgatgtttt
     6541 gctgaatcaa tacgaacccg ggatgactgt cgaaatcctt gataaggtat ttgatcagct
     6601 taaagaagga attctttcga tccgccgtac gctccaagaa aaagggactg aacctgaaac
     6661 agacttttta aatcggagaa tgacgaaaaa acaacagaag agatttgtag tgaaagtaat
     6721 cgaacaactt ggttatgatt ttagtcgtgg tcgtttagat gacactgtcc acccatttat
     6781 gactggaatt aatccgaatg atgcacgaat cacgacacga tggaacgaaa cagatttcaa
     6841 aatggctgtt tttggagtga tccacgaggc tggtcatggt atgtatgaac aagacatcga
     6901 tgataaatat gcgtatacac cggtttatga aggtacatca atgggtatcc atgaatcaca
     6961 atcgttgttt aacgagatca ttattggaag tagtcgcagc ttctggaaaa agcaatatcc
     7021 tttctttcaa gaatgtgcag aaggaacatt cgatgatatt ccttttgaca aattttatcg
     7081 tttattgaac catacaaaat caagtttggt tcgtatcgag gcagacagtt tgacttaccc
     7141 tctccatatc atcattcgtt atgaaatcga aaaaatgatt ttcaatgaag gggtagatgt
     7201 tgctgaacta cctgaaatat ggaatcaaaa atatgaagag tatctgggaa tacgaccaac
     7261 aaatgatgtg gaaggcatcc tacaagacgt tcattggtca ggtgcaagct ttggttattt
     7321 tccctcttat gcattagggt acatgtatgc ggcacaatta cttcattctt tgcagcaaga
     7381 aatagatgtg gaaaatgttc tagcgtcaga cgattattct ccaatcaaaa actggatgtc
     7441 agagcatatc catcaatatg gtgcatctag aaaaccaaat caattaatca tggatgcaac
     7501 acatgaaccg cttaatccgc aatacctgat cgactatatg aaagacctgt attttaatgt
     7561 atatcaggta aaataaaata caatttacaa agatagctga aattcatcta atctatagat
     7621 gttttcagct atttacttaa gaaagaagtg gaacgaatgg ataaattaca agtgatcgct
     7681 gattatagta tggaccaatt agcgcatgat caaacaggac atgggagcga tcataccaaa
     7741 agagttgtca agttagctga aaaaattttg gagacggaac cgcaggcaga ccgctttgtg
     7801 acgcttgcag cagcttacct acatgatacg attgatgata aagtcgttaa aaatgagaac
     7861 gaggcaaagc aacagcttcg tgtattcctt cgctctttgc caatagtaga ggaacagatc
     7921 tcgatgattt tttccattat cgaaaatatg tccttttcta aaaatctctc tgaagcggcc
     7981 gaactatctc tggaaggtaa gatcgttcaa gacgctgatc gtatcgaagc attaggagca
     8041 atcggcattt tgcgtactgc ttatttcggc ggtggacatg ggcacccgat ttttgatcct
     8101 gaactgtatc cgcaaacatt caaggacaaa gaaaattacc gaaaaggcac gacagtgatc
     8161 aatcattttt atgaaaaact gttcttgctg tctgataaaa tgaatactga ttacggatat
     8221 gaagaagcca aacgaagaga aaccttcatg cgtgaattct tagaagaatt ttttctggaa
     8281 tggtctattg acgatgaaaa ttttactcca gacaattgga tcaaaaataa caaaaaatga
     8341 tggaggttgt gacagaagtg gtcagctcca agatatttcg gatcattttc cgtaaaagtt
     8401 acttctggaa cactgtttac caagaggtcg tgagcctgcc gttcagctcc gagtcacaag
     8461 gaacaatttc aaaaaatagc ttctcgtgtt tgatgaatat tgtaacttgt gattcggaat
     8521 tggcaggaga acaccgttta ttcggaagaa taggactgtg acaagacttt tgtcacagtc
     8581 cttttttcga attcaacaag taaaactttt aagaaatatt cagagagtaa aattaaaaat
     8641 tgctgataaa cgaagatgga aattttatgt atttttattg gtctatgcaa taaataaatt
     8701 aaatattcag aatacaattg attttaacga aagggcttct atcaatggtt gtgttgtatt
     8761 tatctgccca ggtagagtaa aatagatcat tatctaaaag gtaattgttc atactatata
     8821 agtcatttga aagtaaaaag atactgtaaa taaaaaatgt ggttaaataa ttctcataat
     8881 cagtgtaagc gttatcaaaa atatagcata cttgctttgt agatgaatga cacgatatat
     8941 gtttggtatg ttctgcaaga cagatgaata tggaggtgga gacaatgtct tccaaagaac
     9001 taacaatgta tttagagaaa gaattggatc aactgaaaga aaaggggtta tacaatacga
     9061 tcgacatact agaaagtgaa aatggtgctt gtatcatcgt agacggaaaa aagatgatca
     9121 atctagcatc caacaattat cttggatttg ccaatcgcga agaattgaaa aaagcatgta
     9181 ttgaagcaac cgaaacttat ggtgtaggag caggagcagt ccgaacgatc aatggttcgc
     9241 tgaaaatcca tcagcaatta gaagaaaaaa tcgcagaatt caaagggaca gaagcagcaa
     9301 tcgcctttca atctggattc aactgcaata tgggcgctat ctctgcagta atgacaaaag
     9361 aagatgctat cttatcggat gaattaaacc atgcatctat tattgacggt tgccgcttat
     9421 ccggagcaaa aatcatccga attaaacatc aagatatgaa agaccttgag aaaaaagcaa
     9481 aggaagcgat agaaagtaag aaatataaaa aaatcatgta tatcacagat ggtgttttct
     9541 ccatggatgg agacattgca cgattgccgg aaattattcc gattgttgaa aaatatggac
     9601 tgatcaccta cgtcgatgat gcgcacggct caggcgtaac tggaaaaggt gcaggaaccg
     9661 tcaagcattt tggattaagc gacaaaatcg atatgcaaat gggcacgtta tcgaaagcta
     9721 taggtgttgt tgggggttat gtagctggat cgaaaacact aatcgactgg ttgaaagcta
     9781 gaagtcggcc attcctattt tctacttcgc taactccagg tgcagctgca gctgcattgg
     9841 cttcgattac tttgatgcaa gaacatccgg aacttgtcga aaaagtttgg gaaaatgcta
     9901 attattttaa agaagaattg aaaaaagtag gctataacat cggtatgtct gaaacaccta
     9961 ttactccagt cattttggga gacgaaaaag tgactcagac tttctctaag aagctgatcg
    10021 aacatgggat ttatgctaaa ccaatcgttt atccaactgt gcctcttggg acaggcagga
    10081 tcagaaatat gccgactgcg gaacatacga gggaaatgct tgatgaagca gtagcagttt
    10141 atcaaaaaat aggaaaagaa atggaaatta tttaactaaa tttagttttt tcgtctattt
    10201 aaaattagag aacatgttca cgcatatatt gttaatcatc tgaagatagt agtaaaaaag
    10261 atcagggagg atcatcatga aaaaagtatt ggtgacagga tgtttaggac aaattggttc
    10321 agagttgatc acacggctac gtcaagaact aggcagtgaa aatgtcattg cgacagatat
    10381 acgcatgcct gaagtcattg agaaaaacga tatctttgag atcctagatg taatggatta
    10441 cgaaaaaatg cgcagcatag cagaacaata tcaagtggac acattgattc atttggctgc
    10501 tcttttgtca gctgttgcag aagcaaaacc acaattagcc tggaatttga acgtgactgg
    10561 gctggtcaat gcattggaag tcgctagaga attccagctg aaatttttta cgccaagttc
    10621 aatcggcgcg tttggtccaa atactccaaa agatcatacc ccacaagata ctcttcagcg
    10681 tcctacaacc atgtatgggg taacgaaggt agctggagaa ctactatgtg attattatta
    10741 tgtgaaatat ggcgtagata ctcgtggtgt ccgtttccct ggattgattt cttatgcaac
    10801 cttgccagga ggcggtacga cagactacgc agtcgatatt tattattcag caatcaaaga
    10861 aggaaagtac actagtttca ttgatcaagg tacatcaatg gatatgatgt atatgccaga
    10921 tgcgatcgat gccattataa aactcatgaa tgcagatcct gatcgattgg ttcatcgaaa
    10981 tgccttcaat atatcggcga tgtcttttga cccggaagag atcaaagcat ctattcaaaa
    11041 aatcatacca gattttgaaa tggattatga tgtggatcct gtacgtcagt caatagcaga
    11101 atcttggcca aattcactag atgtttcttg tgcgcaagag gaatggggct tttcgccgaa
    11161 atacgactta gatgtgatga caaaggatat gttggaaaaa ctgaaagaaa aattggtaga
    11221 gacggtataa aacaagaacc acatccaaaa agttttttat acttttggga ttggctatgg
    11281 tatgaaaggg gacaagggat ggaagaatat caagccacgc cagtaaaaga agtaaaaata
    11341 gaaaatgaat taaaacgtac gatgggattt tttactgctt tatcgactgt tatgggcaca
    11401 gtgatcggtg caggggtatt ttttaaagcc gcaagcgtag cagaagttac aggatccgcc
    11461 agtttgcata tgttttcttg gtttctcggt ggtatgattt ctgtctgtgc aggactaaca
    11521 ggagctgaac tggcagctgc tattccagaa acaggaggga tgattaaata tatcgaacgg
    11581 atttacggaa atacagcagc ttttttattg ggctgggcgc aagtcgtgat ttattttcca
    11641 gcaaatgtag cagccttgtc gatcattttc ggtacacagt tcgtcaatct atttggtctt
    11701 tcccagtcaa tgattgttcc cgtagctgtt acagctgctg tatcgatcct gttgatcaat
    11761 tttttaggtt ctaaagctgg aggggctttt cagtcgatta cgcttgtctg caagcttatt
    11821 cctttgtttg tgatcgtcat tttcggtttg ttccgacaag aaggagtaga cttccaactg
    11881 tttccgatcc aagcaggaga aaatctttca tttttctcag ccttgggagc gggcttgcta
    11941 gcaacgatgt tcgcatacga cggttggata cacgtaggaa atatttcggg agaattgaaa
    12001 aagccggcga aagatttgcc aaaagcaatt tctttaggaa tcatcggaat catgatcgtt
    12061 tatttattag taaatgcggt gttcttaaga accgcatcta tcgacggagt cgcaggaaac
    12121 agcaatgcgg caagtgacgt tgcaaaaatg atttttggcg gcttcggtgg aagactggtc
    12181 acagttggta tcttgatttc tgtttatgga accatcaatg gctataccct tactggaatg
    12241 cgtctccctt atgttatggc aaaagaaaac aacctgcctt ttagcaagct ctttgctaaa
    12301 cttcatgata aaactaaagt tcctgtagcc gcaggtatct tagagctagt catcgctatt
    12361 ggcatgatga tgatcggtgg ttttgataca ctaacggata tgctgatctt tgtcatttgg
    12421 attttttata cgatggtctt tgttggtgtc attcttcttc gtaaaaaaga acctgatttg
    12481 tttcgaccat acaaagttcc aatgtatccg tttattccac tagtagcaat cattggaggg
    12541 acttttatcg tatcaagcac gcttatcact cagacctttt tagcttcgat ggggatagta
    12601 ttgacacttg ctggtatccc gatttatctc tatttaaaac gtagatagct aaaacattcg
    12661 aattttatta gaactgcact tctctgccaa acaaaatatt ttatttaaat gaggagtacg
    12721 tggaagaaat gtcaaaagta ctcgttaatt ttgatcacgt aaatgtcgtt ttgtctacga
    12781 tgaaatagca aagtaaaaga cagaaatcgg gctcaaccga tttctgtctt ttactttgat
    12841 ttgcgtaact gaactattcg gcgtacgccg cgataaatat ttaataaaac caagcaacca
    12901 gaaatgaaaa tgggaagcca aatcagatag acagggtagc caagcacttt agacaaagca
    12961 tgtggagtca ttttatccat ttcaagaagt gcttgctgcc aagtctgaag attgaagact
    13021 agcatgaaac ccgaaataat caggagaata aatcctaaat aatgaattgt agttcttttt
    13081 cttacataag cgatcgtagc ataaaggaac agtaaaaaaa taggtacgcc aaaaacaaag
    13141 tacatattca gcatctcgac accccctttg tgtttatctt actttacttt gaaagaaatg
    13201 agaaataata gcctcgttac ttgcttgaaa cagcaaagga ctgctaagat aagagagata
    13261 caaagaatca aggaggagtc atatggcaag ttatatcgaa ccgattcgtt ttgcgctgat
    13321 tgtttttcca tttttagcct tagcgatctc atctgttttt tttatttatg aatatcgaaa
    13381 gtatggaaca tttctagtaa caagggcagt tattttgtat tctttcgttt tttatttatt
    13441 gtgtgcgtat tttttggtga tcttaccact tccggcaaag gagacggttg cccaaatgac
    13501 agggccaaag atggagctgc atttatttgc ttcatggcaa catttcagag acaacacggt
    13561 attggtcttg tctgaaccta gtacctacct gccggcaatg aagcagagtg tatttttgga
    13621 accagctttt aatgttttat tactcatacc atttggcatt tatttaagat attatttccg
    13681 gctttctttt atgaaaacga tgattgctag tttctgcctt tctctatttt ttgaattgac
    13741 gcagctaagt ggactttatt ttatctaccc aagaccatac cgcttatttg atgtgaatga
    13801 tttagtgaca aatacattgg gtggaatcat tggttttgtc gttacgccgt tatttacatt
    13861 tatgcttcct acaagaagac gaatggatga actttcttat gaaaaaggaa agactgtctc
    13921 attgactcga cgcttggtcg cttatttgat cgactggaca tttttatctc ttattaattt
    13981 ggtagcggcg attttcttta aaattgcgtt cgattcaggg gcagttactt ctcatatctg
    14041 gtggctttta ttagaagtag gggtatactt tatgattgta ccgtttataa ccaatggatg
    14101 gacacttggc aaaaaaattg tgcgtatccg tttggtggaa gaagaccgcg aacgaatttc
    14161 tttaaaagca ttgatgatcc gctacgggta tctgtacttt cttttttatg gtttaagctg
    14221 gttggggcag ttgcttcagc aaatcatgaa ttcgacaacg aatacggtgt tgcagatgag
    14281 tgcagtattc atttctctcg gtgtcttgtt actacaaggt atttttattt taaatatctt
    14341 gctatcattt ttgagaaaaa aacggattct gttttatgaa aaagctagtc acacatatac
    14401 tgttagcacg attggccaaa caaaggatga tgattctcga aattagctga gcaaaaacgc
    14461 tttgtctgtg ttataatgcc aaagtcgtga taatttaaag agaagaggtg cacgaatgaa
    14521 taattttgat atattccgct tcaaaccgtt tatcaatgaa gcgttaaccg caaagggctt
    14581 caaacagccc acagaggtcc aggaacgttt gattccttta attgcaaaag gaaaaaatat
    14641 cattgggcaa tctcaaactg gtacaggaaa aacacatacg tttttgttgc ctttgtttga
    14701 aaaaatcaat gcagaaaaag aggaagtaca agttgttatt acagctccaa gtagggaact
    14761 agctgcacag atctatgaag cagctacaca aatcgctaaa ttttctacac cggagatccg
    14821 tgtctcgaat tttgtcggcg gtacagacaa acagcgtcaa ttaaatcgtc tgcatcacca
    14881 acagccacag gttgtagtag gcacgcctgg tagaatatta gacatgatga atgaacaagc
    14941 gctgaagatt cacaccgcat ttgcatttgt tgtcgatgaa gcggatatga cattggatat
    15001 gggtttttta aatgaagtag accaaattgc aagtcgatta ccagaaaagc tgcagttttt
    15061 agttttttct gccactattc cagaaaaact tcgtccattc ttacgaaaat acatggaaaa
    15121 tccaatcatt gaagaaatca aaccaaaagc agttatttct gaagacattg aaaattggct
    15181 gatttcaaca aaaggtaaag atgagaatca aatgatttat caactgctga caattggtca
    15241 tccttattta gcaatcgtat ttgccaatac aaaacagcat gtggatgaaa ttgccgatta
    15301 cttgaaaaac caaggcttga aagtagcaaa gattcatgga gacatcaccc caagagagag
    15361 aaaacgagtg atgcgacaag tacagaatct ggagtatcaa tatgttgtag cgactgattt
    15421 agctgctaga gggatcgata tcgaaggtgt ctctcatgtt attaatgcag aaattccaga
    15481 agatctagac ttctttatcc atcgtgtcgg acgtactgga cgtaatggct taaaaggaac
    15541 ggccattacg ttatattcgc caaatgatga gcaagccatt gatgcgatag aaaaattggg
    15601 cgtctcattt gaaccaaaag aaatcaaaaa cggggaaatc gtcaaaacat acgatcgtaa
    15661 tagacgtgcc aaacgagaaa aatcaaaaga tgtattagat cccacgctga ttggtcttgt
    15721 gaagaagaaa aagaaaaaga tcaagcctgg ttataagaaa aaaatcgatt gggcaattgc
    15781 agaaaaaaat aaaaaagaac gcaaaatcga acgcagacag caaagccgta ctgctcgtaa
    15841 aaataagaaa aattcacata aataaaaaac aagaggttgt gacaaaaggc gtgtcacaat
    15901 ctcttgtttt taagctagac tttttttcat tccgatacaa agtacttcat cttcaataaa
    15961 aggttctgtg caagtatgat acccttgttt ttcataaaaa tctacagccg tcatttcagc
    16021 tactacataa ctagtctgac aaccttctga aaccgcccgt ttttcagcag cttcaagcaa
    16081 ctgaccgcct aacccttttc ctcggtattc ttttgctacg caaaatcgtt ccggcttgaa
    16141 gcaagtaggt gttttctttt cataacgcaa agtagctact ggtctttttt gatcaagaaa
    16201 tagataatag gtttgttgcg ggatatcttt tccgtcgaat tctagttctg caggaatccc
    16261 ttgttctaat acaaaaactt gatatctcaa aaagcagcta gctgcgcgta tccattcatc
    16321 cgctccaact atttttttca tcatattcct ccttgtcatg aatagcagag atgtattgat
    16381 tcctttattc ttatcgtacc aaaaatcgtg gagtatgacc aaaaggaaat gaaaataaaa
    16441 attgagatat tgacagtgat caatagaatg cgtatactaa ttaagtacga aaaggatatg
    16501 atttgttttt taagactcac agaaaattct ttcttggctg aaaaaagaat agtcactaat
    16561 caaattgctc cctttttcta ttttggtaga aataccgacg cagctcagcg ttatcgagtt
    16621 taagaggtaa tgattacaca tcattgcaat caaggtggta ccgcgagttt tcgtccttgg
    16681 ctgtgatggt gtttttttgt atttaattta tagaaagcag gtaatgacat gaaacaatta
    16741 agtagtgcac aagttcgaca aatgtttctt gatttcttcc aatctaaagg acatacgatt
    16801 gaacctagtg cgtctttgat ccccgtgaac gatccaacct tattgtggat caactctggt
    16861 gttgcaacat tgaaaaaata ttttgatggt tcagttgtgc cagaaaatcc aagaatcaca
    16921 aatgcccaaa aatctattcg aacaaatgat atcgaaaatg tcggtaaaac agcacggcac
    16981 catacgatgt ttgagatgct gggtaatttt tcgattggtg actatttcaa aaatgaagcc
    17041 atccactggg catgggaatt tttgactgat ccaaaatgga tggcattcga tccagaaaaa
    17101 ctttatgtaa cagtttatcc aaaagataca gaagcaaaac gcatctggca tgaagaagtt
    17161 ggcctgccac tagatcacat tattgatgta gaagacaact tctgggatat cggtgcaggc
    17221 ccatgtggtc cggatacgga aattttctat gaccgtggag aagcttataa cgatttagca
    17281 gaagacgatc ctgaaaacta tccaggagga gaaaatgaac gttatttaga aatctggaac
    17341 ttagtatttt cagaattcaa ccataagcct gataacacat ttgaaccact tcctcataaa
    17401 aacattgata cggggatggg attggaacgc atggtctcaa tcgttcaaga tgcgtcaacg
    17461 aactttgaga cagacttgtt tatgcctatt atccacgccg tagaaaagct aagcaaacaa
    17521 gtaaaatatg gtgaaaaccc agtaacagat atttcttaca aagtaatcgc agatcatatt
    17581 cgcgcccttt catttgctat tggcgacggt gcattgccat cgaatgaagg gagagggtat
    17641 gtcttacgcc gtttgcttcg tcgtgctgtc atgcatggga aaaaattagg tattgaacaa
    17701 gcattcttat atcgtttagt ccctgttgtt ggggaaatca tggtaagtta ttatcctgaa
    17761 gtacttcaac aaaaagaatt tattgaaaaa gttatccgta cagaagaaga acgtttcaat
    17821 gaaacaatca atgaaggttt ggaaatctta aatcaagtga tccaagaagt aaaaaacgaa
    17881 aacgggacga ctctagcagg aaaagacatc ttcaaactat acgacacata tggcttcccg
    17941 gtagaattaa cggaagaggt ggcagaagat gaaggactga aagttgatca tgctggtttt
    18001 gaaaaagaaa tggatgcaca acgcgaacgt gctcgctctg cccgcagtac tgaaaaatca
    18061 atgggggtac aatctgcttt attgacagat atcaaagtag aaagtaaatt cattggatac
    18121 acagaacaag aatcagatag tcaattattg gtcatcgtta aaggtgagtc tcttttgaat
    18181 gaagtcgcag aaggtgaagc tcaaatgatc tttgatcaaa cacctttcta tgcagaaatg
    18241 ggtgggcaag tagcggatca aggatggatc atgaatgaag taggcgaaat cgtagcagtt
    18301 gttacagatg ttcaaaaagc gcctaatggt caatttatgc acaccgtaga agtaaaagca
    18361 ccaatgagtg aaggacaaac ctatcatcta ttgatcgatc aatcgatgcg caatcggatc
    18421 atcaaaaacc atacagcaac ccatctactg cacaaggcat tgaaagaagt acttggcgag
    18481 catgcaaatc aagctggttc tttagtcgct cctggacatt tacgattcga ctttacccac
    18541 tttggtcaaa tcacttcaga tgaattagct gaaatggaaa gaatcgtcaa cgaaaaaatc
    18601 tgggaagcta tcccagttga aacaattgaa acagatatcg atacagccaa aaacatgggt
    18661 gcaatggctt tgtttggtga aaaatacgga catgacgttc gagtagtaaa tattggcggc
    18721 tggtcaatcg aactgtgcgg aggcacacat gtagcaaata cagaaaacat cggaatcttc
    18781 aaaatcgttt ctgaatcagg aattggtgca ggcgtgcgac gaatcgaggc tgtaacaagt
    18841 aaagaagcgt acgaactact tgaagaagaa gaaaaacaac taaaacaagt agcaacaatt
    18901 gttaaatcac ctcaattgaa agaagttgtt tcaaaagcgg aacaattgca acagcaagta
    18961 agagagctac aaaaggaaaa tgaacaatta gctagcaagt tagcgaatca acaagctggt
    19021 gatgtattca aagatccaga aacgatcaat ggaaaaacaa tcattgcagc acaagtaaaa
    19081 gtgaaagata tgaatcagct gcgtcaatta gctgaccaat ggaaacaaaa aaatatttca
    19141 gatattcttg ttttagcaaa cgaacaagaa ggaaaagtca gtctgctagc ggcaatgacg
    19201 aaagaatcaa atgaagctgg actaaaagct ggcgacttga ttaaagcaat cgcaccgaaa
    19261 gtaggcggtg gcggtggtgg acgtccagac atggcacaag ctggcgggaa aaatcctgct
    19321 ggtattccag atgcacttaa agctgcgaaa gaatgggttg cgcaacaata gggcgtttac
    19381 gtttgacaga aaaacaaaag ttcaaacatt gaacgaaaca tgattatggg ggcgaagaca
    19441 aacaagtctt gccctcatac ttttttcaat tggatggcgc atctaatcaa atggtcggat
    19501 tcggatggtc tttagttgac gaaagtgaca gaaattttta cgattagtat aaataaaaag
    19561 gggtgaaaaa atgaatagta gaaataagac ctttcgacta gtcttacgtg cgatcttgtt
    19621 agcaatcatc atcgtacaag cgatggttcc ttggctgggg tttattccat taggattcat
    19681 tagtttaaca attatccata tcacagtaat tattgctgca gtagtattag gcccaaaaga
    19741 tggcatggtg attggcttgt tttggggaat cgctacaatt gttcgtgcct atgccatgcc
    19801 aacaacgcca tttgatacat tagtgttcac gaatccgatt atctcggtag ttcccagagt
    19861 acttgttggc ttagtagcag gcttggtttt ccactggatt tatcaaaaaa ataaatcaat
    19921 aacgatcagc tcagcctttg caggggtact gggttcattg gtcaatacag tcttagtgtt
    19981 aggattcatg ggattatttt atacaggtgc aacggcagat gcctatggtg tagactctgc
    20041 tcttttattt aaaaccttag caggggttgc agcaatcaat gggataccag aagcaatagg
    20101 tgcgggaatc ataacaccat tactagcaaa agcgttattt gcagcaacac cgttgaaacc
    20161 agaataatga ccatctttta atagtaatag gacgcacgat agatagaaaa aggaagagag
    20221 gagaggaaaa caatcgtcct ctccatcttt ttacctgagc aacaagcaaa ctagaagggg
    20281 taaaaaactt ggctaagaaa caagaagaaa aaaagaaaca aataccgcaa cagcggacaa
    20341 aaaaaggagt actagcgggt atcttaggat tggttacgaa tctgatcttg tttgtctcta
    20401 agctaatgat cgggcttttt tcaggaagtg tctccattat ggctgatgca gtgaacagtc
    20461 tatcagatac tgcttcatcc atattgactt tgatcggatt taaaattgct gcaaagccag
    20521 cagatcagga acatccttat ggacacgaac gcttcgaata tatcagtggg ttatttgttt
    20581 cgatcatcat tacttatgta ggatttcaat ttttagagtc ttctgctgaa aaaatcatcc
    20641 atccagaaaa tgtctcttta acacccatcg tcttttttgt cctaatcatt tccatctttt
    20701 tgaaatttgc acaaggcaaa atgtatcagg ttattgcgca atccattgat tctgaaacat
    20761 tgagagctac agcaacagat agttataatg atgtctttac tacactggct gtattgcttt
    20821 cagcagcaat cgaatgggta actggatggc gtattgatgg atatataggt tttgctttag
    20881 cattatatat cctttatagt ggattgacga tgcttcgaaa ttttgtatac gaactattag
    20941 gaagtcgccc aacgccagca gagattgaag aaatggaaga gcatttaaat gcttgcgatg
    21001 atatacttgg ctatcatgat ttattggtgc ataactatgg acccaataaa cgctttgcat
    21061 cagtccacat cgaagtagat gaatcaatga atttgaatgt ggctcataag attattgatc
    21121 tgatagaaaa agactttaaa aagtctttgg atgtggaact tgtctgtcac ttggatccaa
    21181 tgcctgttga taacgaaaaa tactataata tcttgcggca gttaaagcaa attcttcttg
    21241 aaacaggtac agggcttaat attcatgatt ttagagtaat tcatcaagga aaaacgctgc
    21301 aatttgatgt agtggtccct gagaaattcc agtttgttga tacagaacta gaaagaatct
    21361 tacgtagtca aatagaagaa aaaatcggag attaccaatt ggaaattacg tttgatcaca
    21421 attatctttt atattaaatg agaaactata aaaagactcc ttaaagtttt taatttaaag
    21481 agtctttttt tcttttaatt gtttatggag agcctgacgt gcaagattat ctgctccttt
    21541 atttttgttt tcgggcaacc attgcaggat caataaagaa aattcggata gaagttcttg
    21601 gattctttga aggtagggaa ggaagagctc gttcttcgtt gcgtttttgt cgaccgtaga
    21661 aactagtgtt ttgctgtctg aaaaacagaa aatcgtttca ttctgtaagt cgtttttctt
    21721 tagaaattct aaagttttta aaaagacttc gaactctgct tgatggtttg tccctataga
    21781 aagcgggata gatagctgtt cttgtttacc ttgatagaca atcaagattc cacctccact
    21841 aggaccaggg ttgccttttg tagaggcatc aatgtatact tttaacataa aaagagattc
    21901 tcctttttgt tcaaactaat gttatggtaa gattatatca ttactgaatc ggtgagaggt
    21961 tagagaatga aaaaaaatat tcgatggcag cctgaactgg cacatacgat catctattgg
    22021 tcattgacct tgatcattct gttttttagt ctgattcttt ctttagaaaa cacaggtcct
    22081 tattggaaaa gcaattttgt tttaggtatt tttcttgttt ttctatttct aggtttgcgg
    22141 cgttctttta ttttaaaatc aaactctgtg attatacgtt atgctgcttt ttggaaagac
    22201 cgagaaatat ctgtcggaca gattcgatct ttgacgccaa ctaatactgg ggtgcaaatg
    22261 atgttgcaag atgagaaagc cccatctgtt ttcatgatgc gaaaaaaaga tcaagtagtc
    22321 ctttttgatc attttgaaaa aaacggaccc aaatcagaat caattcctta tccttatacg
    22381 aaaaaaagaa aaagctaatt ttaaaaatca gaacctaaaa aaacgaattt ttacaggaaa
    22441 agaaaagagt gagacgtacg gttcatcccg tttagcgtct cactctattt gtttatctat
    22501 tcatgcatac tagtatcggt agtctgaacg ttgcctttct tgacatgggc agcttgtgtt
    22561 cctcgattcc cttcgatgat ctcaaattcg accacttgat tttcttccaa agttttgaat
    22621 ccctcttctt caatcgcagt aaaatgtaca aaaatttctt ctgtgtcatc ataactgata
    22681 aagccgtatc cttttttgtt gtcaaaccat tttacaattc ctgtggtcaa agcactcacg
    22741 acctttctaa agtctgatca tagccttcat tataaagagt atttataagt acgtcaaata
    22801 aattaaaaac ctgtaatttt atgttttttt tctgaataaa aaaaggtata attggcatat
    22861 cttaacaaag aagatatttt gttgaataaa gttcgtgaaa aggggtaatc aaatgaagaa
    22921 tgatctgcaa atttcacaag aaacagagct agaaccgatt gttgaagtgg ctagtaaatt
    22981 agatcttaag gaagacgatt tggaactgta tgggaaatat aaggcgaaaa tcaatttttc
    23041 tggaatcaat cgatcaaagg ataacgctga ggggcatttg atcttagtta cttccatcaa
    23101 tccaacacca gctggcgaag gaaagtcaac gatcactgta gggttaggag acgcgctcaa
    23161 taaaatcaat aaaaaatctg ttattgcatt gcgagaaccc tcacttggtc ctgtgatggg
    23221 aatcaaaggt ggtgctgcag gcggaggata tgcacaggta ttgcctatgg aagatatcaa
    23281 cttgcatttt actggtgaca tgcatgctat cacaacagct aataatgcat tatctgctct
    23341 tttagataat catattcatc aaggaaatga attgaacatc gatgcccgcc gagtgatttg
    23401 gaaacgggta gtcgatctca atgatcgtga actgcgtaaa gtaattgttg gcttgggtgg
    23461 gccaatccaa ggtgttccaa gagaagatgg gtttgatatc acagttgcca gcgaaatcat
    23521 ggctatcttg tgtcttgcgg cagaccttga agatttaaag gctcgtcttg caaggatcgt
    23581 tgtcggctat acatttgacc gtcagcctgt gactgctgga gacttgaaag cagaaggcgc
    23641 tctggcatta ctgctgaaag atgcaatcaa gccgaatctt gtacaaacaa tttacggaac
    23701 accagctttt gtccacgggg gaccgtttgc caatatcgct catggctgca atagtatttt
    23761 agctaccaag acagcattga gattagcaga ttacgttgtc acagaggcag gatttggtgc
    23821 agatcttggc ggagagaaat ttttagatat caaagtacct aacttgaaaa aagcgccgga
    23881 tgctgtggtg attgtcgcca ctgtccgtgc attgaaaatg catggcggaa tgaaaaaaga
    23941 tgaacttaaa aatgagaatc ttgatgcttt gaaagtaggt tttgcaaatt taaagcgcca
    24001 tatacgtaat atggaacaat atcagctacc tgtgatcgtc gcaatcaatg aattcgtaac
    24061 agatacagac aatgaactca cactgttgga gcacttgtgt gaaaatcagg ggattcttgc
    24121 caagagagcg agtgtatggg cagatggagc agaaggcggc gttgatttag caaaagctgt
    24181 agtacgattg attgatagaa aagaagctaa ttacaagcca ttataccgcc tagaagaaac
    24241 gatacaagaa aagacagaaa caatcgtcaa gaaaatttac ggaggaaatg gtgttgtttt
    24301 cagcaaaaaa gcgcaaaaac aaatagaaga gtttacgaag aatggatggg acaaactgcc
    24361 gatttgtatg gcaaaaacac agtattcatt ttctgatgat ccttcactgc taggtgcacc
    24421 ggaagatttc accatcacga tccgcgaaat catcccaaaa ttaggggcag gatttttagt
    24481 agccttgact ggagatgtta tgacgatgcc tggtttgcct aaaaaacctg ctgcattgaa
    24541 tatggacgtg acaaatgacg gagaagtgtt gggattgttt taagcttgat tataatctac
    24601 catcgaagga gctgtatttt gactacagct tcttttttta gacgataggg aattaatttt
    24661 gtttacacta ggatcattct ttttctttat tgtattttga gctatactaa agcataatag
    24721 gagggtatga tgaaaacgac atttataaga aaaaccggtt tttacggtat gggtagctcg
    24781 attcagctaa gaatcaacaa tgaaaaacgc agtgttctca gtcatgaaca aaagataacg
    24841 cttgatctgg aagtgccctt tacgatgcag gtcacctttt attggctaaa aagccccgtt
    24901 tatacagtga aagaagcaaa gcctgcttat gtgatcacaa tgaattactt gattcttcaa
    24961 atctatccgt ttttatttct agcaactggg ttgggggccg ttttcctaca aaatttattt
    25021 ttcagttttt ttgcagttat tgtgttgatt gcgttctttt tctatataaa aaaccgggca
    25081 tatttgatca aggaggaaaa ttatggcaaa ctctgatctt tttttaatca gtttcaatcg
    25141 aatcgaaaaa tggatgagag acgagatggg aaatgcacga aatatgggat ttaccgaact
    25201 tgtcagacgc ctagctcaaa gaaaacaatt aatgatcaga aaatacgaag atgatctttt
    25261 acagcttgct cagttaagga atgcgatcgt ccatgatcgg atcgcagtcg attttgtcat
    25321 tgcagagcca aatgattgga cagtcaagcg aatccagctg atcgaacaag aactgattca
    25381 gcctgaaacc gtgctgcctc gatttgcaaa acgtgtaaca ggttttgaac aagatcttcc
    25441 gttacttgaa ctgttaaaga tagtagcaga aaaaaggtat tcacaatttc cgttatacaa
    25501 taaaggaaaa tttgtagcat tgattacttt acgtaatatc gggttttggc tagcaaaaga
    25561 aagccaaaaa ggtccggttg atttaacaaa taaacgagcg ttggatttga tcatccaaaa
    25621 cggaaagtac acaaattatc attttgttcc agctaaaaca catatttacg aggttgaagc
    25681 gatgtttcgt gagcaaggga ctttggaagc cgtacttatc actaaagatg ggaatcccga
    25741 tggtaatctg ctcgggatcg tacgacctcg tgatatttat aaacaaatag aaaaggattg
    25801 attttttgtt aattatttat tggatattca gcgctttgct agtaggagtg gatcagttgg
    25861 tcaaatggtg gatcactgat aatctagcgc ttggagagac gaaaaatctt ataccaggta
    25921 ttttgtcact gaatcatatt cgaaacactg gagccgcatg gagtatgcta gaagggaaga
    25981 tgtggttctt tactatagtg acactcattg cagtcgttgt gattctcaca ttgatgatta
    26041 aaaatcgtga aaaaggtaat cgctggttca tgattggatt gagtttgatt ctagctggtg
    26101 cgattggcaa ttttatcgac cgtattcgtc ttggctatgt agtagatatg ttccagacag
    26161 attttatgag ctttccgatt tttaacgtag cagatgtgac acttgtatgt ggagtgattt
    26221 gtatgttaat ttatattatt ttagatgaaa aggatcaaag aaaaaaatga cagaacttaa
    26281 aacgacgatt caccatgaat ctggtaggat cgataaagta ttgactaatt tattcaccga
    26341 ttacagtcgt tcgcaaattc agctgtggct gaaaaatgga gcggtttctg tcaatggaca
    26401 gccagtcaaa gcaaattaca aagtaaaaca aggagacgag attactgtct tgatccccga
    26461 accagaaaca ttagatgtgg tcccagaaaa tatcccgttg acgatcgttt acgaagatga
    26521 agatgtagcg gtgataaaca aacctcaagg aatggtcgtt catccttcag caggtcatac
    26581 gcatggcaca atggtcaatg cgctgatgta ccatatcaag gatctttcta cgatcaacgg
    26641 cgttattcgt ccaggtattg ttcaccgaat cgacaaagat acttccggac tgctaatggt
    26701 tgccaaaaat gaccaggcac acgaatcatt agctcagcaa ttaaaagata agacctcttt
    26761 gcgcaaatat gttgctttag tccatggaga gattcctcac gaaaaaggaa ccatcaatgc
    26821 gccaatcggc cgttcgaagg aaaaccggaa aatgcaggcg ataagagaag atgggaagtc
    26881 ggctgtcaca cattttactg tattggaacg tttcgaagga tttactctgg ttgaattaaa
    26941 actagaaacc ggaagaacac accagatccg tgtgcatatg aagtatatcg gttatccgtt
    27001 agctggagat ccagtatacg gaccgaagaa aactttgaaa ggcaatggtc agtttctcca
    27061 tgcgcaaatg ttaggtttta cgcacccgac tacaaacgaa aagatgatct ttgaagcacc
    27121 tcttccagaa gtttttgaaa aaactttaga aaaattaaga aaaaacattg cattttaatt
    27181 tagataacgg tatagtaatt aacaacgaaa gcataaaact taatagaatt cctttaagtt
    27241 tagtcccgtg aggctaagaa gggtgggagc aaggatacgt atggtgcgcc ataagtagat
    27301 tgctcattga catagtatag ctatcagtgt atcagtatac gctcagtcta aacattcctc
    27361 ctgtcctctt agggcaggag tttttttatg caaaaaagta gggggaatga aaatgcaagc
    27421 aaaagaagta gtagatcagg taaccatgaa gcgagcattg actcgaatta cttatgagat
    27481 tatcgagaga aaccatagta tccaagatat cgtattggta ggtatcaaaa cacgaggaat
    27541 ctacattgca tcaagaattg ccgaacgcct gaagcagcta gaagatatcg atattcctgt
    27601 aggagaactg gatatcactt tataccgaga tgacaaaaaa gaaaatccag aagaaccgga
    27661 acttcattct tctgacatcc cagtttcctt agaaggaaaa gaagttattt tgattgatga
    27721 tgttttgtat acaggacgaa cgattcgagc agcaatggac gcagtaatgg attttggcag
    27781 accaagaaaa atttcattag cagtcctggt cgatcgtggg catcgagaat tgccaatccg
    27841 tgcagattat gttgggaaga acattccaac atctcgggcg gaagagattt tagtagagat
    27901 gcaagagctt gatggacaag atcgcatcat gattttgaaa gaggaagatt agaggagaga
    27961 gaaacatgtc ggagaaaaaa ggatttcata atgatgacgt ggtgttagat atccacgatc
    28021 gcccaacccc aggacattgg gtaggattaa gtttacaaca cttgttcacg atgttcggag
    28081 caaccgtgtt agtccccatc ttagtaggta tcgatccagg tattgcgcta gtcagttcag
    28141 gactaggtac attggtgtac ttatttacta ctaaaggaaa gatacctgcg tacttaggaa
    28201 gcagcttcgc tttcattgca gcgatgcagc ttttgatgaa aacagatggt tatccagcga
    28261 ttgcacaagg agcagtcaca actggattag tctatttgat tgttgcgctg atcatcaaaa
    28321 agatcggttc agcatggctg gataaaatct tgcctccaat cgtcgtcggt ccagtcatca
    28381 tggttatcgg gttgggactt gcggcaaatg cagcaacaaa tgctatgtat aatcagggca
    28441 cgtatgattt caagtatatt gctgtagcgc tgatcacatt aggattaaca attttcttca
    28501 acatgtggct aagaggtttt ctcggattga ttccgatttt actaggtatt attagcggat
    28561 acatcgtagc cttgctgttt ggaatcgtgg atactaagcc aatcgtagac gctgcctggt
    28621 ttgctgttcc taactttgag attccctttg tacaatatga accaaagcta tatcttggag
    28681 caatcacaac aatggcaccc atcgcttttg tgacgatgac agagcatatc ggccatctta
    28741 tggtattgaa taaactaact aaacgtaatt tctttgaaga accgggtctt cataagacgt
    28801 tgacaggtga tggattagca caaatcgtgg cagcctttgt cggaggtcct cctgtaacaa
    28861 gttacggtga aaacattggt gttctggcta tcacacgtgt ccatagcgtg tttgtgatcg
    28921 gtggagctgc agtatttgca gtcattttag gattcgtagg aaaattaagc gctttgattt
    28981 taagtatccc tggaccagtc atctcaggaa tcagttttat cttatttgga gtaattgccg
    29041 caagtggaat gaagatttta atcgagaaca aaatcgattt tgataaaaag aaaaatctgt
    29101 tgattgcttc agttatctta gtagtaggaa ttggcggact cgtctttgaa gtaggcacat
    29161 ttacattgtc ggcaatggca ttagcaactg tacttggcat cattttaaat cttatcttac
    29221 cagaaacttc acgaagcgaa gaaaactaag gaggaaacat tatgatcatc aaatcagaac
    29281 gtatcagctt aaagcattta ttgaccgttg aggcacttac tgatcaagaa gttatgggct
    29341 tgatccgcag agggcaggaa ttcaagcaag gtgctaattg gactccgcaa aagcgccagt
    29401 actttgctac aaacctcttt ttcgaaaata gtactcgcac acataaaagc ttcgatgtag
    29461 cggagaaaaa actagggcta gaagtgattg aatttgaagc aagcacaagc tctgtccaaa
    29521 aaggggaaac actatacgat acagtactga cgatgtcagc attaggcgta gacgtagcgg
    29581 ttatccgtca tggtgatgag aactattatg acgaactgat acaaagtaaa acaatccagt
    29641 gttcgattat caatggagga gacggaagcg gacagcatcc aacccaatgc ttgcttgatt
    29701 tgatgaccat ttatgaagaa tttggtcatt ttgaaggtct gaaagttgcc atcgtaggtg
    29761 atatcactca ctctcgcgta gctaaatcca atatgcagat gttaaaacgt ctaggcgcac
    29821 aagtattctt ctcaggtcct agagaatggt acgacgatga attcgaagtg tacggacatt
    29881 atatgccatt ggatgaacta ctagatcaag ttgatgtcat gatgatgctt cgggtgcaac
    29941 acgaacgcca tgatggaaaa gaaagtttct caaaagaagg ctaccatcag gaacatgggt
    30001 taacagttga gcgtgcgaag aagttgcaaa aacatgcaat cattatgcac ccagcaccag
    30061 ttaaccgtga tgtagaatta gctgattcat tagtggaagg attacagtcg cggatcgttc
    30121 agcaaatgag caatggagta ttcgtcagaa tggcaatctt agaagcagtg ctaaatggaa
    30181 aagcgtaatt ataggaggat gaaaaaatga aaacactcat taaaaacggt cagatcaata
    30241 cacgaaaaaa tatgacgaca ccagcagaaa tttggataga agatgggcga atcaaagcaa
    30301 tcggtacagg attctcagaa gccgaatttg atgaagtgtt tgatgcaaag ggacaattga
    30361 tcacacctgg tttagtggac gtccatgttc atttgagaga gccaggattt acatacaagg
    30421 agacgatcga agctgggact cgctcagctg ctcgtggcgg tttcactact gtatgcgcga
    30481 tgccgaattt aaatcctgta cctgatacgg cagaaaagct gagacaagta tatgacatca
    30541 ttagaaaaga tgcagttgtg aaggtattgc agtatgcgcc aatcacagaa aatctgcgaa
    30601 gtgagaaatt agttgatcaa gaagcactga ttgaagaagg tgcttttgct ttcacaaatg
    30661 acggtgtagg tgtccaaaca gctgggacga tgtatctggc tatgaaagaa gctgcaaaaa
    30721 acaataaagc cctagtagcc catacagaag atgaatcttt attatttggc ggcgttatgc
    30781 acgctggcaa gaaggcagaa gaacttggtc ttcccgggat cttaagcgta accgagtctt
    30841 ctcaaattgc tagagatctg ttgctagctg aagcaactgg tgttcattac catgtttgcc
    30901 atgtttctac taaagaaagt gtccgtgtaa tcagagacgc aaaaaaagca ggaatccacg
    30961 taacagcaga agtttcaccc catcatctta ttttgatcga cgaagatatt cccgaagatt
    31021 tcggcttttg gaaaatgaac ccgccgctaa gaggacggga ggacagagaa gctttgatcg
    31081 aaggcttgct tgacggtacg atcgattgca tcgctacaga ccatgccccc catggattag
    31141 aagaaaaaag ccaaagtttc atgaaatcac catttggtat cgtaggaagc gaaacagcgt
    31201 ttcaactgat ctatactcat tttgtagaaa ctggtcgatt cacgttggaa caagtgatca
    31261 attggttggc agttaaaccg gctgagattt ttggtttgaa tgcaggaacg ctaacggttg
    31321 gtgcccccgc tgatgtagca gtttttgata ttacacaaac ttgcacgatc gataaagaag
    31381 actttttatc aaaaggggag aatacacctt ttatcggctg gaaagtaaaa ggcgaaacac
    31441 aaatgacttt tgtcaacgga aaacttgtgt ggcagaaggg agaataaaag tatggaacgt
    31501 ttgcttatat tagaagatgg aacagttttc gaaggaaagg cttttggtgc agatgctagt
    31561 gtcttcggag aaatcgtttt tacaacaagt atgactggtt atcaagaaac tatcactgat
    31621 caaagtttta acggtcaaat cattacattt acctatccta tggtgggtaa ttatggggta
    31681 aatagagatg attatgaatc gatttctcca acatgcaaag gagtagtagt aaaagaacat
    31741 gcacgtgtag cttcaaactg gcgaaaccaa atgacgctag attcattttt gaaacaaaaa
    31801 ggaattcctg gaatatcagg tatcgatacg cgcgccctta ctcgcaaaat ccgtgaagtc
    31861 ggaacgatga aagctagtat agttgatgct ggagattcct tcgaacatgc atttgatcag
    31921 ctgaaagcaa ccgttctagc aaccaatcaa gtgcagcaag tctcaactaa caaaccttat
    31981 ccaagtccag gaacaggtcg gaaagtcatt gtcattgact tcggcttgaa acatagtatt
    32041 ttacgagaat tgagtaaaag aaactgtaac ctcacagtac ttccctataa cacagatgcc
    32101 gagacgattt tagcgctatc accagacgga gtcatgctga cgaatggacc tggtgatcca
    32161 aaagatgtgc cagaagcaat cgaaatgatc aaaaaaatcc aaggaaaagt accgattttt
    32221 ggtatttgtc tcggtcacca gttatttgct ttagccaacg gtgcagatac ctataaaatg
    32281 aaattcggac atcgaggatt aaatcacccg gtacgagaag tagcgaccgg aagaattgat
    32341 tttacttctc aaaatcatgg ctatgcagtc gatgaagcca cgattgatcc agaaaaactc
    32401 atcgtaactc atgtagaagt aaatgacgga acagtagaag gagtcaaaca cagagattat
    32461 cccgctttca gtgtgcagtt tcatccagat gctgcccctg gtccgcatga tgcactacat
    32521 ttatttgatg aatttatgga aatgatggac gcaggaaagg agcagtaaac agatgccgaa
    32581 acgtacagat atcaagaaaa ttatggtgat tggatctggt ccgatcatca ttggtcaagc
    32641 cgcagaattt gactacgcag gaacacaagc ctgccttgcc ttaaaagaag aaggatatga
    32701 agtggtttta gtaaattcta atcctgcgac gatcatgacg gataaagaag tggcagatca
    32761 agtatatatc gaaccgatca cacttgaatt tgtatcaagg attcttcgaa aagagcgtcc
    32821 agatgctctc cttccaactt taggcggaca gacaggcctc aatatggcaa tggagctggc
    32881 agcatcaggt attttagaag aattgaacat agaacttcta ggaacaaagc tttctgcgat
    32941 cgatcaagca gaagatcgtg atctattcaa acagttgatg aaagaattga atcagccaat
    33001 ccccgagtct gaaatcgtca atacagtaga agaagctgta gattttgcaa ataaaatcgg
    33061 ctatcctgtc atcgttcgtc cagcctttac tttaggcgga actggtggag gtatgtgtga
    33121 aaatgaagaa gaattacgta tcgtatcaga aaatggatta agtctttccc ccgctaccca
    33181 atgtttgatt gaacgaagta ttgcaggttt taaagaaatt gaatatgaag tgatgagaga
    33241 ttcggctgat aatgcaatcg ttgtctgcaa tatggaaaat tttgacccgg tgggtatcca
    33301 tacaggtgat tctatcgtat ttgcccctag tcaaacattg tctgaccatg aatatcaaat
    33361 gcttcgtgat gcttctcttt cgattattcg agcacttaag atcgagggag gctgtaatgt
    33421 ccaactcgct cttgatccac atagttttaa ttattatgtg attgaagtca atccgcgtgt
    33481 ttctcgttca tctgcgttag caagtaaggc gactggctat ccgatcgcta agctagctgc
    33541 taaaatagcg cttggattaa cattagacga aatgaaaaat cctgttacag gaacgacttt
    33601 tgcagaattt gaacctgcat tagattatgt tgtagctaaa attcctcgct ggccgtttga
    33661 taagtttgaa aacggagaac ggcttttagg cacgcagatg aaagcaactg gtgaagtgat
    33721 ggctatcggt cggaatatcg aagagtcttt attgaaagct gtgcgttctt tagaaatcgg
    33781 tacacaccat atcgaacttc ctgagttggc agacatcacg gacgatgacc taatccaaaa
    33841 agtggttcga gcacaagatg atcgcctgtt ttatgtagct gaagctatta gaagagggta
    33901 caccatagaa gaattagcgg atttgacaaa aatcgattta ttctttttag ataaactgtt
    33961 gcatatcgta gaaatcgaac agcagttgaa acagcagccg ttggatgaca agatattgaa
    34021 aacagcgaaa caaaacggtt ttacagacaa aaaagtggcg gagctgtggg aaataaacga
    34081 agaagccgtt cgccagatga gaaaagaaaa tgatttgatt cctgtatata agatggttga
    34141 cacttgtgca gcggaattcg aatcaaaaac accttatttt tatagttcct atgaatatga
    34201 aaatgaaagt tcacgatcag aaaagccctc aattctagta ctgggatctg gtcctatccg
    34261 tatcggacaa ggggttgaat ttgactatgc gactgtgcat tctgtcaaag caatccagca
    34321 ggcaggatac gaagcaatca tcatgaacag caatcctgaa acagtttcga ctgacttttc
    34381 tatttcggat aaattatatt ttgagccatt gaccttcgaa gatgtgatga atgtgatcga
    34441 gctagaacag ccgataggag taatcgttca atttggtggt cagacagcaa tcaacttagc
    34501 cgaacctttg actgctgctg gtgtaaaaat cttagggaca acgatcgaag acttggatcg
    34561 tgcggaaaat cgtgatttat tcgagcaagc gctgaaagag ttggatattc ctcaaccttt
    34621 aggggatact gctacaagta aagaagaagc cgtggttatc gcttcgagaa ttggttatcc
    34681 agttcttgtt cgtccaagct atgtattagg cggacgtgcg atggaaatcg ttgaaaacca
    34741 gcgagattta gaagattaca tggaacatgc tgtgaaagca tctccagaac atccagtact
    34801 agtggaccgt tacttgcttg gtggtgaatg cgaagtggat gcgatttgtg acggtgaaac
    34861 agtactcatc ccagggatca tggagcatat tgagcgtgct ggtgtccatt caggggattc
    34921 aatggctgtg tatccacctc aaacattatc tgaatcgatc aagaaaacga tcgaagatta
    34981 cacgatccgc ttagcattag gtttgaattg tgtcgggatg atgaatatcc agtttgtcat
    35041 ccatgaaaat gaggtttatg tgatcgaagt caatcctcga gcaagtcgga ctgttccatt
    35101 cttaagtaag gtgacaggaa ttccaatggc acaaattgcg acgaaagcta ttttgggaga
    35161 gaaactaaag acacttggtt atgaaaacgg actttatcca gaaacaaaag aagttcatgt
    35221 taaagcacct gtcttttctt ttacgaaatt gcagaaagtt gatacttact tagggcctga
    35281 aatgaaatcg actggagaag taatgggatc tgacagacaa ttagacaaag ctttgtacaa
    35341 ggcattcgaa gcttctggat tacacttgcc tgaatatgga gccgtattat ttacgattgc
    35401 ggacgaaaca aaagaagaag cactagaatt agctaaacgt tttacagaaa ttggctatag
    35461 tctgatagga acgaaacata cagctgctta tttcgaaaaa aatggtctgg tcgttgaaac
    35521 agtagcgaaa atttctgagg aagcagcaga aaaaaatgta gtcgacttaa taagagatgg
    35581 taaaacacaa gtggttgtca atacgattga taaagatcgg ggaaatgctt ctaaagacgg
    35641 tttcatcatc cgaagagaag cagttgaaca tggtattcca ttgtttactt ctttagacac
    35701 agcagatgcg atcgttcgag tgatggaatc ccgtgctttt tcaactaacc ctatttaacg
    35761 gcgagcacat gttaagacaa aaagacgaaa aaccgttgca ggaggggaca gatgaaacaa
    35821 gaaatgatgg aaatcgttca gcaaaaacag ctggcaccaa agatttttga aatgacattg
    35881 aaaggtgatc tagtaaaaga aatgcagcaa ccaggacagt tcttgcatat tctcgtgccg
    35941 cgtgcagact tgctattacg ccgaccgatt agcttgaatc atatcgacca cgaaacaaat
    36001 acttgccgta tcatttatcg ggtggaaggt gaggggacta gagtcttctc tactctttct
    36061 gccggagacc atttagatgt catgggtcct ttaggcaatg gttttgattt gtccaatctt
    36121 catacaggag acgaagtatt tataatcggt ggaggaatcg gtgtccctcc tctatatgag
    36181 ttatcaaaac agttagtcga aaaaggaatt aagccaacgc attttttagg ttttgccaca
    36241 catgaagtcg tttattatga aaaagaattt aatcgtctag gagaaacaag aatcgctact
    36301 gacgatggaa catacggtat gcacggaaat gtcggtaatt tattgttagg aacgaagacg
    36361 gaacctacag ctgtttttgc atgtggttca aacgggttat tgaagacagt ggaacagctg
    36421 ttttcttcgc atcaaaatgt ccagttatca ttagaatccc gcatggcatg tgggataggg
    36481 gcttgctatg cttgcgtttg tcatacgccg gaagatgaaa caggaacaaa aagtgtgaaa
    36541 gtttgtgacg aaggaccgat ttttaaaata ggagaggtaa ttatatgaat gagaatcctt
    36601 tagcggtcaa acttcctggc ctagaattaa aaaatcctat catgccggca agcggctgtt
    36661 tcggttttgg caaagaatac ggaaaatact atgatttgaa tcagcttgga tcgatcatgg
    36721 tcaaggcaac gactccaaat gcccgctttg gcaatcccac gccaagagtg gcggaaacac
    36781 catctggcat gttgaatgca attggtttgc aaaatcctgg tctagacgtt gttatgcata
    36841 aacttcttcc agaattagag gagtacaatg agttacccat catcgcaaat gttgctggtg
    36901 cttgtgaaga agactatgta gaagtttgta gcaaaattgg cgaagcacca aatgtgaaag
    36961 caatcgagct gaacatttct tgcccaaatg tcaaacatgg cggaattgct tttggaacag
    37021 attctgatgt tgcttttcaa ttaacacaag cagtaaagaa agtttcttct gttcctgtct
    37081 atgtcaaatt gtccccaaat gtaacagaca tcgttccaat cgctcaggca atcgaagctg
    37141 gaggggcaga tgggtttacg atgatcaata ctcttcttgg tatgcggatt gaccttaaga
    37201 caagaaaacc gattttagcc aatcaaacag gtggactctc cggaccagca atcaagcctg
    37261 tcgctattcg tttgattcac caagtagcaa gtatatccag ccttccaatc attgggatgg
    37321 gcggcgtgca gacagtggat gatgttcttg agatgtttat ggctggagca agtgctgtag
    37381 ctatagggac cgcgaatttc accgatccgt atatctgtcc taaactaatt aaagagctcc
    37441 ctgtgcgaat gagcgaacta ggcatcgaat cgctggaaag attaatcaaa gaagtgagag
    37501 aggaacgtga acgatgaatc aactagacca acgaccaatt attgcattag atttttcaac
    37561 taggcaagag gtagaagact ttcttcgatt tttcccgaaa gaagaaaaat tgtttgtgaa
    37621 aatcggaatg gaattgttct accaagaagg acctgaaatc gtacgttatc taaaagaggc
    37681 tggtcataat gtatttttag atctgaaact tcacgatatt ccgaatacgg tcgaaaaagc
    37741 aatgcgggga ttggcaaagc ttggtgttga tctcacctgt gttcatgccg ctggcggtat
    37801 tcgtatgatg gaggcggcaa tgcgaggatt agaagagggg actccagaag gtggaaaacg
    37861 tccgctactt ctagctatca ctcagcttac ttctacaagt gaagaagaaa tgcatgccga
    37921 tcaactaatc gaagtttctt tagaaaaaag tgtgatccat tatgctagct gtgccaaaaa
    37981 agcaggatta gatggtgtgg tttcttctgc ttgggaagta gaagcgatca aagaaatggc
    38041 aggagacgaa tttgtttgct taactccggg tataagacca gaaggaacag tcgcaggaga
    38101 tcagacaaga gtagtcacac cttctcaggc aaaaaagatc ggctcaactt ttatcgttat
    38161 aggtcgacca atcactcagt caactaatcc ttataaagca tatcaaacga ttcaaacaga
    38221 atggagctaa cctaaaatga atgttgaaca aagtatcgca aaagacttat tagaaattga
    38281 agcagtattt ttaaatccaa gtaatccttt tacatgggca agtggaatca aaagcccaat
    38341 ttactgtgat aaccgaatca cgatgagcta tccaaaagtc cgaaaagaga tcgcaaaagg
    38401 attagcaagc aaaatcaaag aagcttaccc tgaagtacaa gtgattgctg gaactgcaac
    38461 agcaggaatc cctcatgccg catgggtagc ggaaatactg gatttgccaa tggtctatat
    38521 tcgaagtaag gcgaaagatc atgggaaagg taaccaaatc gaaggacgta tatttgaagg
    38581 tcagaagatg gttgtgatcg aggatttgat ttctacaggc ggaagtgtct tggaagcagc
    38641 tgaagcagca aaaagagaag gtgcggatat ccttggtgtt gcggctatct ttacgtatga
    38701 gttgccaaaa ggaaaagcaa atttcgaaaa agccgaaatc cctcttatga cgttgaccaa
    38761 ttattctgta ttgattgaag cagctttaga agatcgttat atcgatgagc aagaattaac
    38821 tctgctaaaa gaatggaaaa aagatcctga aaattggcag atttaagcgc gcttgatgaa
    38881 gatagagaaa tccgatttgt gtctccagaa tcatcaattg gaatagcaaa aatccaaaaa
    38941 ctgattgcga gaagcatctt ttcatcaggt atgaaaagaa acttctatcg tgatcagttt
    39001 ttgatttttt taaaattcat ttttctaaga ctggttagca gaaagaagag aataatctct
    39061 tctctttttt ctattatata tagattttct ctattttttg gtaagggagc tgtttcaaaa
    39121 atggtaaaga gcggaaatgt tgcgaatatc agttatttaa tgatatgata ttcggaaaaa
    39181 gaaatctcaa agggaggtaa cttttatggg gttgaatgaa tttattttag gattgaacaa
    39241 tttagagacg atcacaaggg cacctggatt ttttaaatat acagagcata cagttgcagc
    39301 acattcgtat cgtgtagcat ctattgcgca agttctagga gacattgaag aagcgaatgg
    39361 acaaccgatc gattggaaac tgctctatga aaaatcattg aatcatgact acacagagcg
    39421 ttttattggt gatatcaaaa cgccggtgaa atacgcaagc aaagagttaa gagggatgct
    39481 gcaaacagtt gaagaaaaga tgacggacga attcatcaac caagagattc cagctgagtt
    39541 ccaagaagtt tatcgccgtc ggttgttcga aggaaaagat gaaaccgtag aaggagaact
    39601 attagccatt tcagataagg ttgaccttct ttatgaatct tttgatgaaa tcatcaaaaa
    39661 taacccggaa aaagtttata aggagatgtt cattgaggca gtgactacga ttaaaagctt
    39721 tgaacatcgg ccttctgttc agtatttctt taaagagata tttccggaac tattgaacca
    39781 ggaattttat ggaaaagagg cgtttttaga aaccgtctca acgattgtaa agaaagaaga
    39841 aaaataaaaa tgatatgaga tgcaggggga agtatagttg aaaaagaata tggatgtcga
    39901 atggggctat tctggagaca aaggtccgga aaattgggcg agtttatgtg attggtttgc
    39961 gagaggtgcg gaatttccat tgcagtcgcc tattcatttg accaaggggg aagaaaccaa
    40021 aatagaagga gacacgcttt cctttcatta tcaaaagcaa cggtttactg acaaggaatt
    40081 caaaaacacg attcatttag taccttttga ccaactcagt tatgtagagt tcaagaaaga
    40141 acgctattat ttgacagata ttcatttcca cttgccttct gaacatatca tcaacggaaa
    40201 acaggaagat attgaatttc attttgttca tatgaacagc aaaaaagaga atctagttgt
    40261 gggtgtcatg taccagctaa tggtacagga aggttggctg tataatcaag aaaatgggga
    40321 aagttggaac ttagaaaaac atgagcattg ggtaaatccg gatgtgttct ttccggagca
    40381 aaaaagccat ttccattata ttggctcatt gacaactccg cctaccagcg ggccaatcca
    40441 atggtttgta atggatcatg taggaaaact gaaccaagag tttcttctcc ccttcgatgg
    40501 tcagtatgct cgaccgaaca accgaccaat ccagcccttg aatggaagag aaatttatta
    40561 tttcgaggag tttgagcaat gaatattcag cagatgaaat acgtggtcgc tgtagcaaac
    40621 aatggtagtt tcagagaagc ggcaaagaaa atgtttgtct cccagccaag tctttcagct
    40681 ggtatcaaag aattagaaac cgagttaggg atcacgctgt ttactcgaac gaatcgaggg
    40741 gcatatttaa cagaagaagg gcaagacttc ttaaatcgtg ccgagaaaat attggtccag
    40801 cttgatacat tagaaactca ctatctaacg agtgaaaaga gagacaattt ttcgatcgct
    40861 gcccagcatt atgatttctt aggtcctttg accgcacagc tactcgagga attcaaagac
    40921 gagatcaaac aatttcggat catggagacg acaacagcga gagtgatcga agaagtcaaa
    40981 gagcagcaca gtgagatcgg cattatttat atgaatgagc ataatcaagc tggtatcaga
    41041 agatatttac aacaaggaga gctaagtggc cgcagcattg gaaaattcaa aacgcatatt
    41101 tttttaaggc aaggacatcc attagctgaa cacgcagaga tcaccaaaga agaattgtta
    41161 tcttatcctc aagttcgttt tacacaggat ggaaataatt tcccgtattt ttatgaagac
    41221 cttatcgaga tccctgatca agaaacagtg atttatacga gtgatcgagg tactttgatg
    41281 aatatcgttc ttgaaactga tgcttacgct tcaggatctg gtattgtgat tggagggatt
    41341 cgcgagcact tgcggttaat ccctttggca gaaggcgaac taaatgaatt ttatatcatt
    41401 tattcggcga aacgtccgct cagtgaaatc gctcaaagat ttatcaaaga gcttactcgg
    41461 ttactggacc agcagagcta agaaaagcag atgagaacgc tgtttattga acaccgttga
    41521 tcaaaaaaga ggggttgtga cagaattttg tcacaactcc tctttttgta gcaaacaatt
    41581 tataactaat tgctgttgtg ggaaagtacg caaatatgat tctagaaaca ctcattgatt
    41641 acctgttttg tttcatagct gtaatttttt cttcttctgg tgtcacgata atcgtctttt
    41701 ggttttcata aataacataa ccaggcttgg cgccatttgg ttttcggata tgctttacct
    41761 gtacaagatc aaccggcact tgggcagagt atcggtattt tgaaaaatag gcagctaact
    41821 cggcagcttc tgtaattgtt tcatctgagg gcttgtcact tttaatgatg acgtgcgaac
    41881 cgggtatatt ttttgcatga agccaatagt cggttttttt agctgtcttc attgtcagct
    41941 ggtcattttg aagattgttt ttaccaacaa gaatgagcgt tccgtcagaa gaaaagtatt
    42001 gatcaggctg agatggtttc ttacgttttt gtttttttaa gttcttcttt ttcaggtatc
    42061 cttctgaagt caattcttct ttaattgctt cgatatccat tgggccggca atttccagtt
    42121 gagataagac agattcaaga tattggattt catctttggc ttcttggatt tgttcgccaa
    42181 tcagcttaac agcgttcttc agcttttggt atcgatggaa atatttctgt gcattttgat
    42241 ttggtgtcaa tgccggatct agtgctattt tgattggccg atcttcttca taataattag
    42301 gtaaaacaac ttcttttgcg ccgcgtggta cttgtgtcag aaaagtagta agtagttcgc
    42361 catttctacg gtaattctca gcgttttcgg attctttgag tgtttgttca cgttttttca
    42421 atttattttt atttcgtttt agttcatttt cgatttttcg aatcagttct ccgccttgtt
    42481 gttttgcccg atctttctct gctttttcgt gataatagct atctaataat tgactgagtg
    42541 ttggataagc tgttacagca gatgcctgtt cggacaatac ctgataagca atcggtgtga
    42601 aaaaatcttt attttccgtt tcgtaaaaag taggaatagg ctgatggctg atggctgaga
    42661 aaaattcgtc ccatacaacc atcttttcat taggacgttc cagtaatctt ttggtcagct
    42721 cttgagcgat atcgaaaccg attccctgaa actgacgttg gattgctttt ggatctagtt
    42781 cagtttggga aagccgctga aagatttttt ctttctcgga gctaaatggg ttcaagacct
    42841 cttgttttgg cggagcaaca tattctacac caggaagcaa agaacgataa gtgttttgag
    42901 agcttccaat gtgtttgatc gcatccagta tttttccagt ttctcgatta actaagacga
    42961 tcgtactatg acgtcccatt aattcaacga tcaatatgat attttgtaga tcacccaact
    43021 cgtttcgttt agcaaagtgg aaatggatca ctcgatcatt ttcgatttgt tcgatgtctt
    43081 ctaaaatagc gccatccaaa tattttcgaa gcatcatcac gaagttaggc ggattatcag
    43141 gattctgata atcgatttgg gtaatctgta cacgagcata acttgggtgc gcagataata
    43201 ataatcgatg gtttttgccg cgtgaacgaa tcaccagcac gatttcattt tcataaggct
    43261 gatggatttt cgagatccgg ccagatagta acgtttcacg caattcgttg accatcgcgt
    43321 gggtaaatac accatcaaag gacatggttc attcctcatt tcttttcata agtatattca
    43381 ttataacgaa aaaaagaaga aaaaccaatt tggccgaata gtaaagcaaa agtctagaaa
    43441 aatcttggac taattacata aaaaacagtg tttctatcgt tgaaatccaa atttttaggt
//
LOCUS       DAXLPY010000018        40425 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.018, whole genome shotgun sequence.
ACCESSION   DAXLPY010000018 DAXLPY010000000
VERSION     DAXLPY010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.018"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            212..604
                     /locus_tag="ACF3UF_001070"
     CDS             212..604
                     /locus_tag="ACF3UF_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3671216.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACF3UF_001071"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACF3UF_001071"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFD3671217.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACF3UF_001072"
     CDS             2698..2943
                     /locus_tag="ACF3UF_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671218.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3164..4774
                     /locus_tag="ACF3UF_001073"
     CDS             3164..4774
                     /locus_tag="ACF3UF_001073"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFD3671219.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4751..4963)
                     /locus_tag="ACF3UF_001074"
     CDS             complement(4751..4963)
                     /locus_tag="ACF3UF_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671220.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5066..5935
                     /locus_tag="ACF3UF_001075"
     CDS             5066..5935
                     /locus_tag="ACF3UF_001075"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFD3671221.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6100..7371
                     /locus_tag="ACF3UF_001076"
     CDS             6100..7371
                     /locus_tag="ACF3UF_001076"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFD3671222.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7368..8663
                     /gene="rho"
                     /locus_tag="ACF3UF_001077"
     CDS             7368..8663
                     /gene="rho"
                     /locus_tag="ACF3UF_001077"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFD3671223.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8762..9025
                     /locus_tag="ACF3UF_001078"
     CDS             8762..9025
                     /locus_tag="ACF3UF_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFD3671224.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9470..9919
                     /locus_tag="ACF3UF_001079"
     CDS             9470..9919
                     /locus_tag="ACF3UF_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3671225.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9976..11394
                     /locus_tag="ACF3UF_001080"
     CDS             9976..11394
                     /locus_tag="ACF3UF_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFD3671226.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11394..12254
                     /locus_tag="ACF3UF_001081"
     CDS             11394..12254
                     /locus_tag="ACF3UF_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFD3671227.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12428..13201
                     /locus_tag="ACF3UF_001082"
     CDS             12428..13201
                     /locus_tag="ACF3UF_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3671228.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13348..13713
                     /locus_tag="ACF3UF_001083"
     CDS             13348..13713
                     /locus_tag="ACF3UF_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFD3671229.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13861..15069)
                     /locus_tag="ACF3UF_001084"
     CDS             complement(13861..15069)
                     /locus_tag="ACF3UF_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3671230.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15088..15366)
                     /locus_tag="ACF3UF_001085"
     CDS             complement(15088..15366)
                     /locus_tag="ACF3UF_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671231.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15559..16215
                     /locus_tag="ACF3UF_001086"
     CDS             15559..16215
                     /locus_tag="ACF3UF_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD3671232.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16657..17454)
                     /locus_tag="ACF3UF_001087"
     CDS             complement(16657..17454)
                     /locus_tag="ACF3UF_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFD3671233.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17451..18635)
                     /locus_tag="ACF3UF_001088"
     CDS             complement(17451..18635)
                     /locus_tag="ACF3UF_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFD3671234.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18660..19907)
                     /locus_tag="ACF3UF_001089"
     CDS             complement(18660..19907)
                     /locus_tag="ACF3UF_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFD3671235.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20122..21867
                     /gene="dnaX"
                     /locus_tag="ACF3UF_001090"
     CDS             20122..21867
                     /gene="dnaX"
                     /locus_tag="ACF3UF_001090"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFD3671236.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21887..22201
                     /locus_tag="ACF3UF_001091"
     CDS             21887..22201
                     /locus_tag="ACF3UF_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFD3671237.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22226..22822
                     /gene="recR"
                     /locus_tag="ACF3UF_001092"
     CDS             22226..22822
                     /gene="recR"
                     /locus_tag="ACF3UF_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFD3671238.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22886..23530
                     /gene="tmk"
                     /locus_tag="ACF3UF_001093"
     CDS             22886..23530
                     /gene="tmk"
                     /locus_tag="ACF3UF_001093"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFD3671239.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23545..23874
                     /locus_tag="ACF3UF_001094"
     CDS             23545..23874
                     /locus_tag="ACF3UF_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFD3671240.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23888..24826
                     /gene="holB"
                     /locus_tag="ACF3UF_001095"
     CDS             23888..24826
                     /gene="holB"
                     /locus_tag="ACF3UF_001095"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFD3671241.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24862..25686
                     /locus_tag="ACF3UF_001096"
     CDS             24862..25686
                     /locus_tag="ACF3UF_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFD3671242.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25679..26026
                     /locus_tag="ACF3UF_001097"
     CDS             25679..26026
                     /locus_tag="ACF3UF_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFD3671243.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26095..26967
                     /gene="rsmI"
                     /locus_tag="ACF3UF_001098"
     CDS             26095..26967
                     /gene="rsmI"
                     /locus_tag="ACF3UF_001098"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFD3671244.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27076..28197
                     /gene="dinB"
                     /locus_tag="ACF3UF_001099"
     CDS             27076..28197
                     /gene="dinB"
                     /locus_tag="ACF3UF_001099"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFD3671245.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="ACF3UF_001100"
     CDS             complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="ACF3UF_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFD3671246.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="ACF3UF_001101"
     CDS             complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="ACF3UF_001101"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFD3671247.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31683..32450
                     /locus_tag="ACF3UF_001102"
     CDS             31683..32450
                     /locus_tag="ACF3UF_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671248.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32440..34482
                     /locus_tag="ACF3UF_001103"
     CDS             32440..34482
                     /locus_tag="ACF3UF_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671249.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34763..34912
                     /locus_tag="ACF3UF_001104"
     CDS             34763..34912
                     /locus_tag="ACF3UF_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFD3671250.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34923..36437
                     /gene="dltA"
                     /locus_tag="ACF3UF_001105"
     CDS             34923..36437
                     /gene="dltA"
                     /locus_tag="ACF3UF_001105"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFD3671251.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36434..37639
                     /gene="dltB"
                     /locus_tag="ACF3UF_001106"
     CDS             36434..37639
                     /gene="dltB"
                     /locus_tag="ACF3UF_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFD3671252.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37684..37917
                     /gene="dltC"
                     /locus_tag="ACF3UF_001107"
     CDS             37684..37917
                     /gene="dltC"
                     /locus_tag="ACF3UF_001107"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFD3671253.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37920..39188
                     /gene="dltD"
                     /locus_tag="ACF3UF_001108"
     CDS             37920..39188
                     /gene="dltD"
                     /locus_tag="ACF3UF_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFD3671254.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39329..40411
                     /locus_tag="ACF3UF_001109"
     CDS             39329..40411
                     /locus_tag="ACF3UF_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFD3671255.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
BASE COUNT        13016 a         7089 c         8463 g        11857 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga atttcggctc cctattctta ttgaagaata gggagctttg tttattgtct
     3121 gagacttttc ctgcacataa attaaaaagg agtttttgaa cttatgacaa aatatatttt
     3181 tgtgaccggc ggtgtcgttt catcaatcgg aaaagggatt gttgcagctt ctttaggacg
     3241 cttattgaaa aaccgcggct taaaagtaac tatccaaaaa tttgatccat acatcaacgt
     3301 ggatccgggg acgatgagcc catatcagca cggagaagta ttcgtaacag atgatggtgc
     3361 tgaaacagat ttggatctgg gccactacga acgttttatt gacatcaatt tgaacaaata
     3421 ctccaacgtg acgacaggaa aaatctattc tgaagttttg cgtaaagaac gtaagggcga
     3481 atacttggga gcaactgttc aagttattcc tcatattaca aatgagatca aagaaaaaat
     3541 catgcgagca gctaaaatga ctgattcaga tgtgatcatt acagaagtag ggggaacagt
     3601 aggggatata gaatctttgc cattccttga agcacttcgt caaatgaaag cagatgtcgg
     3661 tacagataat gttatgtata tccatacaac attgattcct tacttgaaag ctgctggaga
     3721 aatgaaaact aaaccaacgc agcacagtgt aaaagagcta cgtggtttag gtatccaacc
     3781 gaatattttg gtggtacgta cagagcaacc tgtttctcaa agcgtgaaaa acaaattggc
     3841 acaattttgt gatgtcgaac cagaagcagt tatcgagtcg ccagatgtag atacacttta
     3901 ctccatccca ttagttttac aagcacaagg aatggatcaa attgtttgcg accatttaaa
     3961 actagataca ccagaagcag acatgacaga atggaaagaa ttagaagaac gtgtcttgaa
     4021 cttgaagaaa aaagtacgga ttgcgcttgt cggtaaatat gtcgagttac cagatgcata
     4081 tatctcagta gttgaagcat tgaaacattc tggtttcgcc tataattcag acatcgagat
     4141 cgattggatc aaagcacaag aattaacgag agaaaatgta gaagaacgtt tgaaagacgc
     4201 agatggaatc ttggttcctg gtggatttgg tgatcgcgga gtagaaggga aaatcgaagc
     4261 gattcgttat gctcgcgaaa atgacgttcc gtttttaggt atttgtcttg gtatgcagat
     4321 ggcttgtgtc gaatttgcac gtaacgtcgt tggattagaa gatgcgtcat cagctgaaac
     4381 gaatccagat acagcaaaca atattattga tttaatggct gatcaggaaa acatcgagaa
     4441 tttgggtgga actttacgcc ttggattata cccatgtaaa atcaaaaaag gaacgaagac
     4501 ggctgaagca tatgatggag ccgatgttgt gcaagaacgt caccgtcacc gctatgagtt
     4561 caataacaaa tatcgtcaat tgtttgaaga acaagggcta gtcttttcag gtgtctcacc
     4621 agataaccgt ttagtagaaa tcgtagagct gccagagaaa aaattctttg tgggatgcca
     4681 attccaccca gaattgattt ctcgtccaaa tcgcccgcaa aaattaatca aagcatttgt
     4741 cggagcatca ttagcagatc acgaaacaaa ataatttttg aacttgatag aaagagaaaa
     4801 gtagcaagag aaggggataa gcaattttct tgtcactttt ctctttttct gatttgttat
     4861 tatttgtagg aaaaaagata gaaagcaaaa gacttttttc gattaaagcg ctattggata
     4921 ttttattttt tgcaaaaaac ttcttgaaaa ttttcatttt cattgatttt agtagaaaac
     4981 taccgaaatg tttggtaaaa tagggtcgtt ggttaagaat tgtcttaaca aatttagttt
     5041 tacaaaactt aggaggaatt ttattatgcc agtagtatca ggagctgaat ttttaaaagc
     5101 tgctcgtaaa ggcggttacg ctgtcggcgg attcaacaca aacaacttgg aatggactca
     5161 agcaatcctt gaagcggctg aagcaaaaca agcaccagta cttatccaaa catcaatggg
     5221 tgcagctaaa tacatgggtg gttacaaaat ctgtaaagat ttaatcactg atttagttga
     5281 agcaatgaac atcactgttc cagttgctat ccacttagac catggtgatt acgaagctgc
     5341 tttggaatgt atcgaattag gctatacttc agtaatgttc gatggttcac atctaccatt
     5401 tgaagaaaac ttgaaattag ctaaagacgt tgttgaaaaa gcacatgcaa aaggtatctc
     5461 agttgaatgt gaagttggtt caatcggcgg agaagaagac ggaatcatcg gtaacggcga
     5521 attagctgat attgaagaat gcaaacaaat ggttgctaca ggtatcgact acttagcttg
     5581 cggtatcggt aacatccatg gtcaatatcc agaaaactgg aaaggattag cttttgacca
     5641 cttacaagca attgctgatg ctgtaggtcc agacatgcct ttagtattac atggcggatc
     5701 aggtattcct caagatcaaa tcgaaaaagc tatctcaatg ggtatctcaa aagtaaatgt
     5761 taacactgaa ttccaattat catttgctgc agctactcgt aaatatatcg aagctggtaa
     5821 agataaagaa ggtaaaggat tcgaccctcg taaattatta gctccaggta aagcagcaat
     5881 cgttgaagat gctaaatctc atatcgactg gttcggttca gctaacaaag cgtaagcatc
     5941 cacataacag atacgatata taggaatgga gaacgacttt tgaagtcgct ctccattctt
     6001 ttttacttaa aacggcagac catgctcgtt tctttttttt atctatgata aaatacaagc
     6061 atatccatga aaaaagatta ataaacaagg tggaaacaga tgaaaaaaat cgtaatcaaa
     6121 ggaaaccgac ctttagctgg tgaagtaacg atcagcggtg caaaaaatag tgcagtcgca
     6181 ttgattccag ctgcaatctt agctgattcc ccagtgatct tggaaggtgt gccggacata
     6241 caagatgttc attcattaat tgaaatttta gagatcatgg gcgcaactgt ccatttttcc
     6301 aacaacatac tagaaatcga tcctcgagaa gtcgtatcga ttccgatgcc gcacggaaaa
     6361 atcaatagtt tgcgtgcttc ttattatttt atgggaacac tgcttggtaa atttggcgaa
     6421 gcggtagtag gcctgccagg tggctgttat ttaggcccta gaccgattga cctacacgtc
     6481 aaaggatttg aagctctagg tgctgaagtg acaaatgaac atggtgccat gtatttacgg
     6541 acagaaaata aaggattgcg tggcaatcgg attttcatgg acgtggtttc agtcggagca
     6601 acgatcaatg tgatgttagc tgctgtaaaa gcaaaaggac agacagtaat tgaaaacgct
     6661 gcacgagaac cggaaatcat agatgtggca actttactga ataatatggg ggcaaaagtt
     6721 cgaggagcgg gtacagatgt gatccgtatc gaaggagtcg aaacattaca tggctgtcgg
     6781 catttcatga ttcctgaccg catcgaagca ggaacctatc tagcattagc agctgcagta
     6841 ggaaatggta tcaaagtgaa aaatgtgatc tttgaacatt tggaaagctt tatagcaaaa
     6901 ttgcaggaaa ttggtgtcca tatgaaaatc agcgaagatg aaatcgaagt ttacccctcg
     6961 aaagaattaa aacccgcaaa catcatgacc tatccttatc caggatttgc cacagatctg
     7021 cagcagccac ttactgcgtt actattgatg actacaggca cttcagaaat catcgatacg
     7081 atctatgcga aacgtgtgaa ccatgtgccg gaactagcac gaatgggcgc tgatattacc
     7141 gtggaaggaa atatgatcat cgtgaatggt ccaaataaac ttcacggcac agaagtcgtg
     7201 gcttctgatc ttcgggcagg tgcttgttta gtgattgctg gactattggc agaagggaca
     7261 acgacgattt acaatgtaga ttatatctta cgcggttatg atcatattat cgagaaacta
     7321 acagccttag gggcatcaat tgaaatgata gaggaagtgg gagctgaatg agcgattatt
     7381 tgacaatggc agaactagag aacaaaacgt taaaagaagt ttatagttat gccaaagaat
     7441 ttaaaattcc ttattacagt aagatgaata aaaaggaatt atctctagct gtgattcgtg
     7501 cacaagcaga gaaacaagga ttttattata tggaaggaat attggatatc gttggtcaag
     7561 atggttacgg ttttttacgg ccaatcaatt atggaccaag tgcagaagat atctatattt
     7621 ctgcctcaca aatcagacga ttcagtttga gaaatgggga caaagtggca ggaaaagccc
     7681 gtccacctaa agaatcggaa cgttattatg gtttgatgca cgtggaaagc gttaatggaa
     7741 aagatccgga agaagcaaaa gaacgtccgc attttccagc cttaacacct ctttatccgc
     7801 aaagacagct tcaactggaa acaacaccgc aaagactatc tacccgaatg atcgatatct
     7861 tttctccaat cggttttggt cagcgtggat tgatcgtcgc accgccaaaa gcagggaaaa
     7921 cttctgtatt aaaagaaatc gcaaatggta tcaccgaaaa ctatccggaa gtagaattaa
     7981 tcgttctact gattgatgaa cgaccggaag aagtaacgga tctagaacga agcgtgaaag
     8041 gcgacgtggt atcttctaca tttgatctgc agccgcaaaa ccatactcga gtttctgaat
     8101 tagtattgga acgcgcaatg cgtttagtcg aagataaacg agatgtcgtt atcttgatgg
     8161 atagtattac tagacttgct cgggcctata acttagtcgt tccaccaagc ggacgtacat
     8221 tgagtggcgg gattgaccca gccgcattgt ataaacctaa gaaatttttc ggggcagcaa
     8281 gaaacatcga agaaggtggc agtttgacga ttttagcgac cgctttagtc gatacaggaa
     8341 gccgtatgga tgacgtgatc tatgaagaat tcaaaggaac tggaaatcta gaattacaac
     8401 tttcacgtga attatctgaa cgtcggatct tcccagccat cgatatcaaa aaatcaggta
     8461 cccgaaaaga agaattattg atgccaagtg aagaattaga agaaatttgg aaacttcgaa
     8521 aaaatatgac tggagattca ttagaatata cggaacaact gatccgcttt ttgcgtaaaa
     8581 caaaaaacaa tcagcaattt ttcaaagaat ttcaagatgt ctcctttggt aaaaaaaatc
     8641 cgaccagaaa tctgaaaaga taattgcaac cttgactgaa acatgttaag atgttaatgt
     8701 tgtaaatcga caaatcaact ctggttcagc aaatggagca gggcaaagga gcgaaaaaat
     8761 catgaaagaa aacatccatc cagattacca cccagtagta ttcatggatt caacaactgg
     8821 tttcaaattc ttgtcaggtt caacaaaaac ttcacaagaa acagttgaat gggaagacgg
     8881 taatacatac ccagtcatcc gtgtcgaagt aacttctgac tcacatccat tctacactgg
     8941 acgtcaaaaa ttcacacaag cagacggacg tgtggaccgt ttcaacaaaa aatacggtct
     9001 caaagacgca aacgctgcgg aataataaaa acgctgataa ctcaacgttt agcagactat
     9061 ctgataggga tagtctgttt ttttatgttt tttgccaatt taaaacttcg tttgatgctg
     9121 aaaaagtcgt aggatcataa tgcacaaaac aatgaaaaac tagtatatag ttttaattat
     9181 ccacttgata aaaacacctt atattaacga aatgaagagg ggttatttcg aagtaaaaaa
     9241 ccatttacct aaaattagaa gctaagcttt cctttcaagg aaggcttttt gttttgttat
     9301 agacttgcga ttgtttgtga gctagatcgt tcattttaat gacttataca cgcggatgat
     9361 gggtcttttt cctctgttca ttcataatat tgaacggtac agctagcgat gctatactga
     9421 cctcagttcc aagaaaacgt taacattttt tgtgggggag aggtttttta tgaggtttga
     9481 tcaattgatc gcagaagaac tgattgtttt cgatccatcg atagattcaa aaggatcatt
     9541 atttgagcga ataggggatg tgttgaaaaa aacaaataag gtaagaaatg ttcaaaaagt
     9601 cgttaaggca ctattcaaac gagaggagga gatctccaca ggaatagaag atggatttgg
     9661 gattccccat gcaaaaagca aatatgtgac aaaaccagca ctgtgttttt ttcatacagc
     9721 caaattaacg gactatagcg ggatagatga aatgccaatt gaatatattt ttgccatcgt
     9781 agttcctgaa aaatcagcag atatgcatct agagattctc agcacactct ccagacgatt
     9841 gatgaatgca gattttagaa agggaataaa agaagccact acgccagcag atatcatcag
     9901 acagattagt caagaatgaa aatagtagag tctttgtccg agtatcgata gtgaagaaaa
     9961 aggaggaaaa taatcatgaa aatcgttggt gtaactgctt gcccgactgg aattgctcat
    10021 acttatatgt cggcagaaaa attagaagta acagcaagaa atctaaacca tcaagcaaaa
    10081 ttcgaaacac aaggtgtaaa aacagaaaat cagttatctg aacaagaaat caaagaggca
    10141 gatgcaatca ttcttgcagt agataaagaa atcgaattgg accgatttgc cgggaaaaaa
    10201 gtaaagcgtg tctctacaag ccgagcaatc aaagaaccgc aagtagtaat agacgaagca
    10261 ttgagagata ttggcgtatt cgttgtgtct aatgaaaaag aaccagctgc aaatgagaaa
    10321 aagccgacaa tctataatca tttcatgaat ggtgtgaatt acatgcttcc atttgtgatc
    10381 gcaggcggaa tcatcatcgc actgagtttt gcctttggga ttacagcggc tgatcccaac
    10441 tcagcagact ataatgtgtt agcagctgca ttttcaagga tcggaggaga tacagcgttt
    10501 gccatgatgg ttcctgcgtt aggcgcgggg attgctacat cgattgctgg aaaagcaggt
    10561 tttgccccag gaattgttgc cggattactg gcctctacag gtggttcagg ttttcttggc
    10621 ggaatgattg gtggcgtgct agcagggtat atctgtgatt ttctggcaaa taaaattagc
    10681 gtaaaaaaag aattttctgc tatttatcag ctgattgtcg tccccttttt atcgatctta
    10741 attattgggc ttttgatggt atttgtgatt gaacaaccga tcacatgggt gttggatgct
    10801 ttgacaaatt ggctgaatag cttgggaaat acatccgggc tattgttcgg attacttatc
    10861 gggatcatga tggcagctga tatgggtggg ccgatcaata aatcgacttc gactttctcg
    10921 atcggtttga tgtcagctgg agtaaatgca ccgattgctg cttgtatggc tgcaggaatg
    10981 acacctcccc taggtattgc tttagccact ttattattca aacataaatt taccaaagaa
    11041 gaacggactt caggtcaatc atgctggatt ttaggcgctt cgtatattac agaaggtgct
    11101 ataccgtttg cggtatctga cccgatccgc gtgataccta gtttgatgac aggttcagca
    11161 gtcgctgcag ggatttccat ggcagtagga gttacttcaa tggcacctca tggagggatt
    11221 tgggtgatgc taattccaaa tgttatgaac aatttaccta tgtatgtctt ggcaattgca
    11281 tcaggtacag tcactacagc ctttatgctt ggactattga aaaaaacagt gaaagagaaa
    11341 aaacaagaca agtggacgaa aaatgaaaat ctaacaaatg aggtggaagc gtaatgttat
    11401 atacaatgaa agagttattg aaagtggcta aagagaatca atttgcagta ccagccttca
    11461 atatttgcag ctatgatatg atgaaagcaa tcatcgaaga agcagagaga ttagaagcac
    11521 cagtaatctt agaaattcat cctgatgaaa tcgcctattt aagtgatgag tttgttgcgg
    11581 cagtaagagc ctatgcttat acaagtaaac tgccgatcgt tatccacttg gatcatggcg
    11641 gtacgataga agatgtctta cgggcgattc gaaacggcta ttcttccgtg atgatcgatg
    11701 cgtctttgaa atcattcgac gacaatgtac agattacgaa aaaagtggtt gcgttagctc
    11761 atgcggtaaa tgtctcagtg gaggctgagc ttggaacgat tgggaataat ggttctgctg
    11821 aaggaggtgc tgaaacaatc atttatacag atcctgatca agcgaagatt tttgtgaaag
    11881 aaacaggaat cgatacactt gctgtagcaa ttggaacagc gcatggcttg tatccgaaaa
    11941 acagaactcc aaaattaaat atcgacttac tgaaagaatt gaaccaacaa atcgatcttc
    12001 catttgtttt acatggcggt tcaggtaatc cggacgcaga agtcagcgaa gcagtaaaat
    12061 acggagttgc caaagtgaat ttgagctcag atcttaaaag cgtctttttc aatgctttga
    12121 gagaaatatt gagtgaaaat ccatcgatgt acgagccgaa tgcaatttat ccagcagcta
    12181 ataaaaaggt acaagaagtg gtcaaacata aaatggaaat tttgaacaca gtaggcaagg
    12241 ctagtttata ctaaaaataa aaatgtgtgg tcaagagggt atgacaatag tcttgtcata
    12301 ccctcttaac cacacacgat gttcagaagt agttttttcg aaaaatttct tcttatttct
    12361 cgaagccaat cacttctgtc acaacctctt ttttcctgtt actatataaa gtaaatgggg
    12421 tgattttatg ttgaatgaag tggagaatag acagcaggag attgtgaatt atctaaaaaa
    12481 caaccaattt gcaagagtca ccgatttgat cgagttagta aattatagcg aagccacgat
    12541 taaacgtgac cttgtttttc tggaaaaaag tggattgatc cgtagagttc gcggtggcgc
    12601 catgcttatt gacaatcgaa aaattgacgt gccttacctg atgaagatca ccaaattaga
    12661 agaagaaaca gaaaaacgta agattgcaga tacagcttct tctttgattc gagatgatat
    12721 ggtcttattc ttggattcca gtacaacctc tttacactta gtcagaaacc tagcaagatt
    12781 tgatggtttg cagatcatta cgaatggcat cgtcacagct gctatgttga gtgaatatac
    12841 aacggcaaaa gtatctgtat tgggaggggc aattgttccg aaacgagcaa caatcaacgg
    12901 ttcaaaagcc tataacgatg cattgtcata ttatgcggat ttagcgataa tgagttgtcg
    12961 cgggctagat ttcagccaag gagtaacaga aactcatgaa ggagaggcaa tggtcaaaaa
    13021 agcttttaga aaacaatcag accggcttgc cgttttagtt acacagcaaa aaattgcaca
    13081 taaattcatg catcaagcca ttgcttttca tgaaatcgat tatctggtga caagtaaaga
    13141 actgacaaaa gaacagtatg cgaaagtaaa ggaacaccat atcgaatgtc tgtacggata
    13201 aattattacg tgaatgttct aagtggcttc ctcattttta gataggacct tatctttgct
    13261 cgcttctctc agccgatggt ataataatga aaaggttatc ttgttagata atcttacttt
    13321 tttatccagg agaaaggagt gcagaaaatg aaacatgtga aggcgttggt agtgaaggca
    13381 atcatgatct gggcgattct gtgggtcgtg ctgacaggtt tatacggtgt tagctttatg
    13441 gattcaacga ttgttggggt aattattgta gtcatgatct atgtgctagg ggatctgttg
    13501 atcttacgta aagtagggaa catcgcagcg acgatcgcag atgctggttc agctgcagtt
    13561 atcttgtggc tctatctata ttttatgaat gatacagtcg atatttggat gaaagtattg
    13621 attcctgctc tattgatcgg tgtggcagaa tggttcttcc acaagtggtt gctaagtcaa
    13681 ggcatcgtac cagatgaacg gaaaatggaa taaatcaaca gttaaactat tcttatcgat
    13741 aaatgaaagc tttaaaaata aatagatgtt taattaagaa taatcataaa ctatttttac
    13801 tcaaaaaacc gctcagatta ttttcagatc tgaacggttt tttttatcta ttcatcaaga
    13861 tcaaatttca tttttcaatg attcaatcaa ttcgccctct gcttcatgac tatgttttcg
    13921 gccattaaca agatagagtg ctgtacatat caatggaatg actccggcaa tcacatacaa
    13981 tcctctaaat gaagtaagag attttagcat ccccatcaaa taaggaccaa cgcctaagcc
    14041 taggtctaaa ccaataaagt aggtagataa agcaatactg attcgatgtt cgcggacgat
    14101 ttttaaacaa acagcctgtc catttgacat aaacgtacca taacctaggc cgactaatgc
    14161 tccagagata agcaatgtca cactattcgt cgttacactc agtaaaaata atcctgctgt
    14221 taagaataaa tagctaggat acatcacgta ttgttctcct ttgacatcga aaatccttcc
    14281 agtcaatgga cgtgtaaatg tgatgaccaa agcatatacg acgaagaaaa atgacccagc
    14341 agcaactaag tggattactt ttgtataaga agataaaaat gataaaacac ttgaataaga
    14401 aagacccatc aaaaaggcaa ttcctgtaat gaaaagtgct ttcttttcaa taaaactatt
    14461 gatattccat gagcgaagag atattttttg ttcttcagat aatggaatat tttttacagg
    14521 aaagacaagg caggcaatcg taacaaagaa gaccagtaca attgaaaacc agataatgaa
    14581 acgaaaatca gtcatattca gcaaaatcat tcctaaaaat ggcccaacag cggcagctaa
    14641 actagtactt aatccataat aattgatgcc ttcccctttt ttagatgcag ggatatatgc
    14701 agtaacgata gcatttgtag ctgtagaaac tgtaccgtag ccgaatccat tcaagaatcg
    14761 aactaaatac aatgccccga tagttggcgt ataaagatat gctaatgttg aaaggagata
    14821 gaagatcgcg ccgcctctta aggtaaactt ccgaccaaat agttctaact gtttccccat
    14881 gaataagcgt gccagcaatg ttccgatgat atagatccca gaagcaaaac ctgcttggct
    14941 caagctggcg tgtaaggtgt cttgcgcaat gactgccatg atgaccatca acagataata
    15001 aatcaggtag acaataaaat tgatcaatgt gattccaata aaatatttat taaataattt
    15061 cttttccatg tatgttatac attcccctta agctgaatat gcttttaatt tttgtatttg
    15121 aacttctaca tcgtgataat tggatggata gcgatcaaca agttggcgaa taaataaatc
    15181 tcttgtagac ataaacagat ttaaaaattc ttcgcattcg tttgttggat tctcatccac
    15241 tgctttgatc aattcgatcg agttttgata cgcatcattt aaaaagacta aagaagcttt
    15301 catatcaaat cttgtttgat atgctgtttc taatcgatta atgattgtgt tcatccagta
    15361 attcatgttt tttccctcta ttcttaaaaa attttacttc tgcagtataa cgaataaaaa
    15421 aaaggaaaaa aatcgcataa gtgatggaaa aaggtactta acaaatgtta atatcattag
    15481 taaaatacct ttggacttta aaaagtttta aagtactgta tgatcttttt agatgaaagt
    15541 ttggatgggg gagcatcatt ggatagtaga gtcttaaagg aatatttgga taaaaatgat
    15601 tttccgatta tacgcaaagg atatcataaa tatttgacat tcgaagggat ggaagattcc
    15661 catacgtata tcttgaaaga gggaacggta aaagcaagtg ttatttcaaa tgatgggaga
    15721 gaatttaacc ttcgctatat caaagatctt gaaatcgtct ctcttttaaa agacgaatat
    15781 tcacaattca tcgattcgcc gtataatatt cgagttgaat cagaatatgc agagttttat
    15841 cgaatcaatc gtgtgcgctt ttggcaaaat atcaaccaag acccaaagct acaacactat
    15901 gtaaaagagt attaccgcta tcgtctgctt tattcgatga aaaaaatgca gcaaatgcta
    15961 ttaaacggaa agctgggagc tgtttgtacg caactttacg aattatatga tttattcggt
    16021 gtgcggacag aagaagggat gctgatcgat ttttcgatca cgaatgaaga aatcgccaaa
    16081 ttttgtggca tctcaactgc tagcagtgta aacagaattt taaaacaact gaaaaaagat
    16141 ggtattatca ccgttaaaga ccatcatatc gttattttga atatggactt gttagaagac
    16201 aatattatct tttgatgaac aaagaggttg tgaaatcagc gttttgacct gagtattaga
    16261 gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
    16321 agctgattga acaccgttta ccaagaggtt gtgagcctgc cgtttaactc tgagtcacaa
    16381 ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagga
    16441 gttggtagga gaacaccgtt taccaagagg ttgtgaaaaa gctgttctgc atcaagtaat
    16501 aagaagagcc aagtaaaaac agtctcttat gtttttaact tggctggact tatcaccgta
    16561 gatgtaagct tttgaacgcc gtttatttgc aacaaaaggg gctgtgacac gatttttgtc
    16621 acagcccttt ttttgcgaac attcatttag caatttttag aaacttctgc cgccaccgcc
    16681 aaaagtcccg ccaccgctag aatgggtagt acttccgcca ccgccgcttc caggaggtgg
    16741 gcttttgggg attcttcttg tcgtgacaaa agaatttgtc agacgatcgg ttttttcagt
    16801 taatttgata ctggattttt ctcggaatgg atatttgtag atgcctgatt tcaattgata
    16861 acgcgaaaca gtcacaaaat aaaagacaag actaaggata agagccaaaa caacagcaat
    16921 gatgatttct actgtcgtca aaaccttata gcgtgtaatt ttgccagttt cttcgtctac
    16981 acgataatgt cctcctggaa ctccgtcttc cacatatgtt gctgatttag acaggtaagc
    17041 ttttgcagca ttgtaatagg cagcatttgt catctgatca taaacatcat ctaagatcga
    17101 atcgattctg ctatcagtca aataatcgat catattacca gaagtcgaaa tgtagatttc
    17161 acgctgtccc atatctaata gcaatactga gccattttga tcatttccga ctgcgtctct
    17221 taagtaatta tcagcaaagt ctcttggttc ttctgaatta gatgtagtcg ttacgatcaa
    17281 gactcgtcct ttgatttttt cattcagctt ttctgcctgt tgttccaaag attggatttg
    17341 atctgttgtg aataacccag cctcatcatt taccgtagct gtatctgcat gagtagccac
    17401 cggccagcca acacttacta gcaaaagaaa gaataaaaaa aattttttca tcatatcaag
    17461 taacctccga tcagaaagag gatcgctagc ccagcgaaaa tcccaagagc ggtcagtccc
    17521 aattttttct ggctgatcgg caggacaccg ctgacctttc ctgtttgtcc attcattgcg
    17581 tagtagtaga cttttttact tgagtcattg cttcgataag taacaagcca taccggcagt
    17641 aatacgtaat tatttacttc gtttgtgatt gaagcagaag ttcgcacacc ggtcaatgtt
    17701 gtatatccat ttgcggtatc ttttaacagc ttctctgaat agtcttttaa ttcagattga
    17761 atctgtgatt tgattgcctc atattcgata tctctttttt ctgcttggaa cccggctaaa
    17821 tactggcttt taaaatcaat tgctttatct aacgggaaag gttgcacgcc ttcgaccatc
    17881 ttttgttgcg tattttttga taaggcattt tttactagtt ctttaaaaga aagcttgcct
    17941 gctcttgaaa cagcaaattg cttcgtttct gtgtattcga tgtcacctat ccgccatatg
    18001 cggataactg taccattcgc ctgcatggca ccatctactt cagcatctgt agcccaataa
    18061 gggaaataca cacctgtcaa cttatcgatt tgatccttat tgaaaaaagc tttgggaaca
    18121 aaccattttt tcttggtcca agcgagaaat ctgttgattg cttcttcttt ctcgacagca
    18181 aaaggaagta ctttatttgg caagaattct ccgcttaaac gtcccgatag tacgacggga
    18241 ttatggcagt agtaacaata agtcgcagca gttgtcgcat cagtcacgat ctctgcacca
    18301 cagttgggac aaagaaaaag atctatcgct gcggtattat ctgcagattc gtccgctgta
    18361 tctgaaaaac cgcctgcctc gtcaaccgct ttgcgctcgg cttcattcat atcggcaagc
    18421 tgttcttggg ctgtaaaagt aaaatcttcg gtaggtgaag gttcttcttt gctttcttcg
    18481 ccagccatac gcgcttcttt ttgcttttgc tcatattggc tgacttcttc ttctgtatag
    18541 atattcaggc agtattcgca atgaaatttt tggtctttgg gatcaaaagt caacggaccg
    18601 ccgcaattag gacatttatg tgtaagaaca tccatcagct gcacaccttt ctaaataaat
    18661 taattaacgg ggattccttt aaacggttta ccacagtttg gacagaattt agggatgccg
    18721 ttggaaagat ccacgatctc attgcattca ctgcatcgca tttgtagctt aggctgaacg
    18781 ttttctacag gtttggcagc tccgcagttg gaacagaatt ttccggaatt ttctgtcccg
    18841 caaactggac atgtccaagt atccgcattt ccttgtgcag tttgttgatt ttgtttttct
    18901 gcttgttgtt tgatttgttc ttggttattt tgagctgctt gagaaagata agaaccattt
    18961 gcattcattc ccatacctac acccataaag ccggtcattg ctcctgcttc attttttccg
    19021 gctgcttcca taccacgtgc aatggaacct tgcacgtatc cttcacgtac gctaggatca
    19081 cctagcatcg ccccttcgtt acgcatattg atcagtttca cagaatcatc ggtgtaagaa
    19141 atgctggcta cagccacaga aacaatctcc atcccacgta attcacgcca agaatcatcc
    19201 aatgcagtat ccatgtattt gcttaattcc aaactcttag atggtacata agaaatccgt
    19261 tgaccatctg cagacatctg attgattgct gattgtagcg ctgttaggaa ttcagctaaa
    19321 tactgctcat tgatatcatt gatttccact tgtgttttgt ttttagggat tgcgtttgta
    19381 taaaataaaa tcgggtcaac gacatgaata gaataagtgc catgtgcccg taagaataat
    19441 tctgcgttat agaaattgtc aaagtagttc aacggcgcgc ttgtaccgaa tttgattccc
    19501 tttatttctt ggagattgat ataaaaaact tgttgtttct gcggtgtgac gccgccaaat
    19561 ttgaatcggt caaaagtttc agcaattgct tctttcagtg ttccattgaa catggaagga
    19621 gctgcgtcat ttttaatggt gtaataacct tcctcagcgg tataatcgat gatttttcca
    19681 ccatcgacca aaagcatcat catgtttgga tagacatgga cgactgttcc gtctgttaaa
    19741 acatcttctg ttcctttacg attggagcca cgtttgtcat ctttgcggac tttgacacct
    19801 tttgtcatga ccgttgtatc actcatattg tctggttcga tgacttctag ccattgatct
    19861 gccagaccgc cgccaaccat acttgttgct gctttgataa gacccataaa aaattcctcc
    19921 tctgattcag ctagtgccaa acaattattg tttatttatt ataccatagg aagatgtgaa
    19981 acttctcgga ctagagacgg aattgaaatg gaaaattgcg tattgtttaa atacctgaaa
    20041 aagccgagaa ggatagtagt ttttttacct aatatcacgt ataataagag atagtgaatt
    20101 ttttaaaaaa gggggatcct tatggcatat caagcacttt atcgagtctg gcgttcgcag
    20161 cgtttcgaag acatcgttgg acaaaaagct gtgacacaga cactaaaaaa tgctattgtt
    20221 tcccacaaaa cctcacatgc ctacttgttt acaggaccca gaggaaccgg aaagacgagt
    20281 gcagcaaaga ttttcgcaaa agcaatcaac tgtccgaaca gtaaagacgg tgagccatgc
    20341 aacgaatgcg aaatgtgtcg atcaattact gctggtacgc aagaagatgt gatcgaaatc
    20401 gatgctgcca gcaataacgg agtcgaagaa atccgattta tccgtgatcg ggcaaattat
    20461 gcgcctacaa aggcagcgta caaagtgtac attattgatg aggtacatat gctttcaaca
    20521 ggagctttca atgccttgtt gaaaacattg gaagagccaa aagaaagtgt catattcatc
    20581 ttagcaacga ccgaacctca caaaatacca gctacgatca tttcacggac tcagcgattt
    20641 gattttaaac ggatcaatac ggcagatatt gtcgaacatc ttgaatttat cttgaaagaa
    20701 tcgactatca gctatgaacc agctgcattg aatgtgattg cccgttctgc agaaggcggg
    20761 atgcgggatg cattgagtat tcttgatcag gcaatctcgt ttagtgaagg aacaattact
    20821 ttagatgatg ccatgcaagt gacaggtagc ttaactgacg aaatgatgga cagttacttg
    20881 agtgcttgcg tgaaaaaaga agtaccagaa gcattggaaa cattgaacca aattctcgca
    20941 gccggcaaag aatcacgtcg ctttctagag gatatgttac aatactgccg tgacttgctg
    21001 atgtatcagc aagcacctaa cctagttgag gaacaatcga gtacgatcag aagtacattt
    21061 acagaattgg cacaaactgt ttcagcggat cagctgtttt caatgataaa gattttgagc
    21121 gatactcaaa atgaaattcg ttttaccaat agtgccgcta tttatttgga agtcgctaca
    21181 gtcaaacttg cacagctacc gtctgcttct gttccttcag cagatgtagc atttgcagat
    21241 gatcagatag taaaacagct acaacaagag attaaggaac taagaaacga aatcaaggaa
    21301 ctacgcagta atacaggaat tgagaataca aaagtacagc cggtacagca aacaaatcat
    21361 aaaaaacaga caagtaccta tcgtgtaccg acggaacgag tatataaagt tctgcgggaa
    21421 gcgacaagac agcatctgaa ccaagtaaaa gaagtatggg aagacttgct gatgagtcta
    21481 tctgtcactc agcgagcaat gcttaaagca agcgaaccag ttgcagctgg acctacagga
    21541 ctagtgattg cgtttgatta tgagattgtt tgtcaaagag cagcaaatga cgaagaattg
    21601 cagctttcgg tacacaacaa cttaagccga atgatcaaag attatgcgcc tgatcctgtt
    21661 tatattacaa gagaaagctg gccagaactt cgaagaaatt atttgacgca ggcacaagaa
    21721 gagggaacag aaaactcttt tgcttctgaa gactcagaag gagaaatcga gttgcttcct
    21781 caagaacaag aagtaccaga agaaacactt gtagtaaaag cagaggaact gtttggctcc
    21841 gaagctgtta cagtggtaga tgattaataa aaaggagtag ataattatga tgcgtggaat
    21901 gggcaatatg caaggcatga tgaaacaagt acaaaaaatg caaaaagaaa tggcagaagc
    21961 acaagagctg ctaaataaaa cagagtttac aggtaaagcc accaatgaat tggtcaaagc
    22021 ggtttttaca ggcgatcgtc gcatgaaaga tatccaaatc aatgaagaag tcgttgatcc
    22081 tgatgatatc gagatgcttc aggatcttgt cgtaatggca gtcaatgatg cgatcgcaca
    22141 aattgatgtg gaaactgaga aaaaattagg gaaatacgca aaaggtttgc caggatttta
    22201 gttttaaact gaaggagtaa tgaatatgca atatccagaa ccaattgcga aactgatcga
    22261 cagctacatg aaacttccag gaatcggtca gaaaacagcg acaagactcg ccttttatac
    22321 gatcgatatg aaagatgaag tagtaaatga atttgctaaa tctttgttaa gtgtaaaacg
    22381 cgatttgcat ttttgtagta tctgcggaaa catcacagaa gaagatccct gcgaaatatg
    22441 tagaaatcct tcacgtgatc gaagcgttat cctagtggtc gaagagccga aagatgtaat
    22501 ggcaatggaa aaaatgcgag aatatcacgg actttatcat gttctccatg gtgtgttatc
    22561 accgatggaa gggacaggtc cagaagacat caatatttct tctctgttgc agcggctgca
    22621 tgatgcagat gtaaaagaag tgattatcgc aacaaatgca acaacagagg gagaagcaac
    22681 agctatgtat ctctcacgtc tgatcaaacc cgcaggtatc aaagtgactc gtctagcaca
    22741 tggtctgtct gtaggctctg atatcgagta tgcagatgaa gttactttat tgaaagctgt
    22801 cgaaggaaga cgtgagttat aaatttctaa ttaagtgttt tttcagatac aatataaaag
    22861 cagcacaaga gatgggggca acaatgtgaa cggactattt attacaatcg aggggcctga
    22921 tggtgcagga aaaaccagca tcttgaatga actttaccct cttttgaaag aagtagcaaa
    22981 aacagaaatc attcaaacaa gagaaccagg aggcattccg attgctgaag agatccgagc
    23041 agtgatcctt gatccaaaaa atgatcggat ggatgaacgt acggaagcac tgctttatgc
    23101 agcagcaaga agacaacatc tagtcgaaaa ggttctgcct gctctggcaa aagggaaaat
    23161 cgttttatgc gatagatttg tcgacagttc tcttgcttat caaggtgcag gccgacgcat
    23221 cggcgttacc gagattgctc ggttgaatga gtttgctaca gaaggtacta cgccggattt
    23281 taccctttat cttgacgtag attcagacac cggattaaga agaatcaaga aaaacagaca
    23341 aaatcaaatc gaccgtttag attcggaagg tttggaattc caccagcgtg tacgtcatgc
    23401 ttacttaaag ctggcagaag agaatccgga aagaatccac aaagttgatg caagaaaaag
    23461 ctttgaagaa gtgctgcaaa caagttatca tacaattatt gaacagtatc cgcaattttt
    23521 tgaaaactag gaaggtgaac gtttatgaaa attattttag cgattatcca agacaaagac
    23581 agcaaccgtt tatcaaatga attgattgat gcaaatatcc gtgccacaaa actatcatcg
    23641 acaggcggct tccttaaggc tggaaacagt acgtttatcg tgggtattga agatgaccgt
    23701 gtagaagaag cattggaaat catcaaaaaa acgtgtgaat caagaaagca atttgtatct
    23761 acacctgtta cactggatat ttcgatggat gggggcgtcc cttatccagt agaagtagaa
    23821 gtaggcggtg ccacagtctt cgtcttacct gttgaaggat tccatcaatt ttaggaggag
    23881 ctgagctatg aatcaagaaa taaacttggc tcaaatgcaa ccgatcgtgt atcagcagct
    23941 tcaacggagt tttgagcatg ggcgtatcgc tcatgcttat ctttttgaag gggagaaagg
    24001 aacaggaaaa catgaagtag gtatatggct tgcacagcac ctgttctgta cccaaatgaa
    24061 agacaatctg ccttgtggaa aatgcaacaa ttgtcagcgg atcgaaaaga aagaacatcc
    24121 agatgttttg gttattgaac cggaaggaca aaccatcaaa gtcgatcaga tcagacgttt
    24181 gcagacggaa ttcagtcgca gcggttacga atcaagaaaa aaagtttttt tgatcaaaga
    24241 agctgaaaaa atgaatagca gtgcggcaaa cagtttgttg aaattcttgg aagagccccc
    24301 tggagatttt ttagcggtgt tagaaacaga tgcagtagga agaattctcc ctactattca
    24361 atctcgttgt caagttctgc attttcaaga actttcgaaa gaagcactga tccatcgatt
    24421 gcaagaagag cagattccat tggaaaaagc aaaacttttg gctttcttaa caaacagttt
    24481 aggaaaagca gttgaaatct ctcaagatga atggtttaat gatgctaagg acttgattta
    24541 tcaatggttc gtttacttgc aaaagcaaga tactcaagcc tttatctatg tccaaaaaaa
    24601 attggtaaaa tcatttaaag aaaaaacaca acagtttaca ggattatctg tcttgatgtt
    24661 ttattatcag gaagcacagc gtcaagcagt agcaaacggc gaatatggca aagtgaaaca
    24721 gataaaccag ataattgaac ggatattgat cgcagagcag aaactacgca gcaatgtcag
    24781 ttttcaggct gttgcggaac agttcgtttt gcatacgatt ttttagcttg ccgcaaagga
    24841 tgatgatcaa ggaggatgga aatggtagaa gtagtaggtg tccgatatag agatgcaggt
    24901 catatctatt attttgcacc aggagactct gaatatgttt atagtgacaa ggtattagtc
    24961 gaatctcagc aatccttaca tattgctact gttgtccttc ctaaaaaaga gattgatccc
    25021 aatgaccttc ctgaagctat ccgtccgatc ttgcataaag cgtcacaagc tgaattagaa
    25081 aaagacaaaa aaaacaaaaa agatgcttat gatgcattga aaatcgcaaa agaaaaagtg
    25141 cagttgcgtg agttggaaat gaaaatggtc aaagccgaat acacatttga tcgaaataaa
    25201 ttgatttttt ctttcacagc ggacgggcga attgacttta gagaattggt aaaagatctg
    25261 gccgctgtat ttcgtactcg tattgagctt cgacaaattg gtgtccgcga tgaagcaaag
    25321 ataataggcg gaattggtcc atgtgggcgt ccattatgct gttcttcttt tttaggcgat
    25381 ttcgtgcctg tatcaatcaa aatggcaaaa gatcaaagtt tatctttgaa tccaacaaaa
    25441 atttccggtt tatgcggacg cttgatgtgc tgtctgcaat atgagagcga agaatacgag
    25501 acagcgaaaa aagaactccc tgactttgga aaagtaattg ctacacctga tggtaaaggg
    25561 aaagtcgtag ggttgaatct gcttagccgt atcgttagta ttcggctgac tggacgggaa
    25621 aatcctgtcg aatatgaatg ggatgaattg aaagaattta tccaagtagg tgagatgaat
    25681 ggataagaga tcattatacg acggattgaa tcaattagaa tcagagttga gaaatacatt
    25741 aacagaactt gttgaaatga agcatgcttt gcatgagatc gtagaaaaaa atacaacttt
    25801 ggagatggaa aatcaacgtc tgcgggaaca cctgcgggaa ttgaaccaag ttgcacaagc
    25861 tccagctgaa aatgtgaagc aggaactttc taagtctcgt atgaatcttg aaaaaattta
    25921 tgaagaagga ttccatgtct gctacgattt atatggatca agaagggaca atgacgagcc
    25981 ttgtgcgttt tgtctagaag tgatctatcg cgaaagcggt cgatgaccaa taacaagagg
    26041 agactggagc ggagaaatac tgctccagtc tttttattaa ggagattgtg acagatgtat
    26101 aatcaaaaaa gtttcaaggg aaatccggta tatggggatt tatatcttgt accgacgcca
    26161 attggaaatt tagaagatat gagctacaga agtgttcgta tgctgcaaga atccgatctt
    26221 atcgcaagtg aggatacgcg taatacacaa aagttattga atcattttga aatccataca
    26281 ccccaaaaaa gtttacatga acataattat aaagaacgtg tccctcaatt gattgctttg
    26341 ttaaaagaag gaaaaacgat tgctcaagtc agtgacgcag gaatgccttc catcagcgat
    26401 cctggacatg agctagtttt agcctgcata aaagaaggga tttctgtgat ctctatccca
    26461 ggacctacag ctgggatgac ggctttgatt gcttcagggc tagtgcctca accattttta
    26521 ttttatggct tccttccacg taagaaaaaa gaacagaaag aaacattgaa aaagctaaaa
    26581 gaacagacag ttacgctgat tttttatgag tcaccttatc ggatcactgc tacattgacg
    26641 aatttcttag aaatttttgg aaatcgccaa gtcgttttgt gtcgggaatt gacaaaggtc
    26701 catgaagaat accttagagg aagtacggaa gagctactcg cttatatcga agaacatcca
    26761 gtaaagggtg aatgttgtct gcttgtagaa gggaatttgt tcgaaatgcc agtgacggaa
    26821 gttgatgaag agttgggaac gttaaaggaa caagtagaag caaagatcgc ttcaggcgaa
    26881 aaaccaaatg ctgctatcaa agcagtagcg ctgaaaaatg ggctgaaaaa acaagaagtc
    26941 taccgtcagt accatgaatt agactgagat agtataagtt gtctataatg aaagactaat
    27001 gaggaaatca gctactaact tttcaaatct cttgaacgcg aacgaatgtt cttgtataat
    27061 gaataagagg tgaggatgat ggagctgcaa tttcctttac ataatgatac atcaagaaaa
    27121 atcattcata ttgatatgga tgcttttttc gcttcggttg aagaacgaga tcatcctgag
    27181 tttcgcggac atccattagt aattgccaga caccccagtg acactggtgg gcgtggagta
    27241 gtgactacag caaattatga agcaagaaaa ttcggaattc attcagcaat gagtgcacaa
    27301 aaagcgtatg agctttgtcc gcaagccatc tttaagcctg gcgaccatca taaatacagc
    27361 gatatttcca aacaagtacg ggaagtattc tatcgttata cagatattgt ggaaccagtt
    27421 agtatcgatg aagcgtatct tgatgtgacc gaaaataaaa tcaattgcaa gtcagccatc
    27481 aaaatcgccc gaatgatcca agcagatatt tgggagagtg tccagctaac atgttctgcg
    27541 ggagtaagtt acaataagtt tttggccaaa ttagcatcag actatcaaaa acctagagga
    27601 atcacggtag ttgcccctca agacgctgtg ccatttttaa aagctttgcc aattgaaaaa
    27661 tttcatgggg tagggaagaa aactgtacct agaatgcatg agctagggat ttatacagga
    27721 aaagacctat atgaatgcac agaaatgatg ttgattcgaa attttggaaa aatgggctat
    27781 tctctttatc gtaaagtcag aggaatccat gattctccag taaacgttac aagagagcga
    27841 aaatctgtgg gaaaagagca tacttatggg cagccgttgc aaacggaaga agcagtgctg
    27901 actcagttgc gccaactagc tgaaaaagta gaagaagcac tgagaagagt ccaaaaacat
    27961 gggaaaacag tagttttgaa ggtcaggtac acggactatt ctactgtgac caaaagagtg
    28021 acattgccag aatatatcta taaaaaagaa gcactctttt atcaagcaag ccttatatgg
    28081 gaggaaatct tgggagtaga aaaaggaatc cgattgttag ggattacttt gacgaatctg
    28141 gacccgatga cttatgaaaa catcgtcctt ccattatggg aaaatcaaga aatataaaaa
    28201 cagctttgag agttgaaacc ggaaatccgt tttctctccc aaagctgttt ttatatcaag
    28261 tcttgctttt tgatttgttc ataggtttct gttgcatccg tacatttttc ccaaatcaca
    28321 acttgattgg attctaaaga tttttggacg tcaatgatcc gctggttgct acttccgcga
    28381 aattgtagtt ttaggtcacg tttgcttaat tcaaagcgtc cgtcaacaag gatatcgatt
    28441 tgcgaaagga gttctaattt atcttctgaa tcttgtagca attcatcaaa ggtatagcct
    28501 gtccatgacc agatatcttt tgtcgtaccg aactcttttc ggatacgtcg tacgacttgc
    28561 agacaaacat ctgtattcaa aaaaggttcg ccaccaagta aagttaatcc ttgcacgtaa
    28621 tcgttgcgca agtcagcgat gatttgttct tctaattcag gtgtgaatgg tttgccatat
    28681 cggaaatttt gtgcagcttt gttgaagcag ccttcgcagg caaataagca gccactaacg
    28741 taaagactgt tgcggacacc ttcaccatcg acaaaattaa acggtttgta gtcagcaata
    28801 tagttttggc tgtagtcttt tgctaaccat tcttttggtt ttggatttct cataaaaaaa
    28861 cttctttcat ttaaggttca aagatatagc tattgaagat aaaatctact cgaccacata
    28921 aataagaaca aactgaccta aatccattgt tcaagaaagc ttgttcttat tttgatagag
    28981 ggcgttcaaa gatacaaagc catcgaaaga gggtggtgaa aaaagacttg tcatagcctc
    29041 ttattctgaa taaacggtgt tcaaaagctt gcatctgcag taataagccc aactaaacga
    29101 aaaatatgag gaactatttt tgtttagcta ttcttattac ttgatgcagg acagcttttt
    29161 cacaacctca tttcatgtgt ttcacacgtg aggaaatttc tttatggcgg ccatgtacca
    29221 tcggacgagc ttgcggattt cctaaatagc cacaagtacg tttgactaca tcacatgttt
    29281 ttggatcatg atttccacat tctggacatt cgaaccctcg ttctgtcggt ttgaaatcac
    29341 cttcgaaacc acattgatag caatgatcga ttggcgtatt cgtaccaaga tacccgattt
    29401 tgtcatatgc aaaatcccat acagcttcta aagctttcgg attttgttgg agcatagggt
    29461 attcacagta gtggatgaat ccacctgaac aatattttgg ataatccttc tcaaattcca
    29521 atttttcaaa tggcgttggg tttttacgca catcatagtg gaaactgttt gtataatatt
    29581 ctttatctgt gatattttcg atgatgccga atttttctgt atccaaacgg cagaaacggt
    29641 cagttagact ttcacttgga gttgaataga cactgaaatg ataaccatat tcatcccccc
    29701 atgcatctgc attagctttt aattctttga cgatatcaag tgtgaaagct tttgcttctg
    29761 ggtttgtttc ccattcgcca ccgaagaaag ctgaagcaac ttcatacaat ccaatgtagc
    29821 ctaacgatac agtagctcga cggtttttga ataattcatt gacagaatcg gtacgtgaaa
    29881 gacgtttccc gaaagcacca tacatatata aaattggcgc atttgctgga atggcttctt
    29941 tacaacgttc tacacgatag agaagcgcat ctttcatgat ttctaagcgg tcagacagta
    30001 actgccagaa tttattctga tctccttttg attcgatcgc gattcttggc aaattcaatg
    30061 taacaacacc taaattcatt cgtccgacat ttacttcttg accattttcg tctttccacc
    30121 cttgcaagaa tgaacgacag cccataggta ctttgaaact tccagttaat tcaacgattt
    30181 tatcgtaatt cagaatatca ggatacattc ttttcgttgc acattccaat gctagttgtt
    30241 tgatgtcgta attaggatct tcagggttta agttcacacc ttttttcaaa gtgaagatca
    30301 gtttagggaa gatagctgtc cgcttttcac tccctaatcc attgattcga atctgtaaaa
    30361 ttgctttttg aatttctctt tcaaaccagt tttctcctag tccaaatcct aatgaagtga
    30421 aaggagtttg tccatttgaa gtaaataagg tattgatttc atattccaaa ctttgcatag
    30481 catcgaagat atcttttttg gtttttgctt ttgcatattc tttttggcgt tctggcgaat
    30541 cgatccattc ttccgcgtct tttagatgtt ttttatagtt caattctgca aaaggagcaa
    30601 gcaattcatc tgttcggtcg gcagaacagc caccatattg acttgacgct acattggcaa
    30661 taatctgtga gatttgtgct gtggcggtct ggatagattt tggcgattcg acttcggcat
    30721 tgccgatttt gaacccattg ttcagcatgc ctttgaaatc aatcaagcag caattcgtca
    30781 tcggtgtata aggatgataa tccaaatcat ggtaatggat atcgcctttt tgatgcgcat
    30841 ttgctatatg tggtggcaac attttcagtc cgattgattt tccaacgatc ccggctgtca
    30901 gatctcgctg tgtattgaaa acattactgt ctttatttgc gttttcgttc acgacagttt
    30961 ggtccttgtt gattagcttt tcaatcgaaa agttgatatc tgttgcttta ctgcgagcaa
    31021 aatctcgttt ggtacgataa ttgatgtact cttctgctaa ttcatattcg tttttttcta
    31081 gtaatatatg ttccacgatg ttttgaatct catagatttt gacattttca gcaaaccggc
    31141 ttttgatttc ttggacaacc aagtctgcaa tcatttgaat tttttcataa gtaagtggtg
    31201 ataatgagcc gtgaattttc ttttctgctt tgatcagtgc ttcattgatc ttttgttcat
    31261 cgaaatcaac atggcggcca tcgcgtttga tgactttcat ctgggatgtc tctggctgct
    31321 gagtaacgac agttttttct tcataattta ctttcattat cttcaactcc tgctaaattg
    31381 ttcttgtcta tcataaaaca aaatcgggga aggagcaact aaatatcggc tatatatagt
    31441 attcaatgtg ctgtataatt ggatttctat actatatgta gtgtatattt tattgtgaaa
    31501 aaaggtgaaa acttgtagct ggtggatttg ttttttgcat atttaatttt gctgaataaa
    31561 ataattgaat aaaatttttt attcagtcca agtaaaagtg acaaaaacat aagagcaaat
    31621 tattcgtaga tatgctacta tgcaaataaa tagaaatgaa aaatgaaaga ggaggagaag
    31681 aattggaaaa gatgatcgaa gtgaaacatc taagtaaaag ctacggcagc aaactttctc
    31741 ccgtcaaagc cttagataat atctcattca cagtagaaga aggcgagttt gttgggatta
    31801 tgggcccaag tggtgcagga aagacaacgc tgatgaatat cttgtccacg atcaatttgc
    31861 ctacgatggg cagtgtctcg atccaaggaa aagaaatcac aaaaatgaaa aacagtgagc
    31921 tcagtgactt tcgtcgaaaa aaactaggat tcatttttca agagttcaat ttgatcgata
    31981 ccctaaatgc aaaagacaat atcctattgc ccctagcagt tgaacggatg actaaagagg
    32041 aaatggaaaa gagagtaaga catgtagctc aattgttgaa tatagaagaa ctgctcaaac
    32101 ggtatcccga tgaactttct gtcggacaga gacaacgaat tgcagctgct agagcacttg
    32161 ttgttcagcc acaagtgatt tttgcagatg aaccaactgg ctctttggac tcgaagtcgg
    32221 ctacagaatt gttgaactac ttgaagacca tgaatcaaaa agaaaaagca acgatactgt
    32281 tagtcaccca tgatccatat acagcaagct actgcgatag aattttattt attaaagatg
    32341 gtgtgatttt ttctgaagtt gtcagaagag ggacaagaag agagttcttt gagaaagtaa
    32401 tagacatgca ggcgacgatt ggcggaggag gaaaaatgaa tgctgtataa actagccgtt
    32461 aaaagttttt ttcggcagtc acgaggctat cttgtttatt ttttcagttt gactttatcc
    32521 gtaatgatct attattcctt cagcgcaatg acctacgatc aatctttagt cagaagagca
    32581 agtcaagata cttcgataga tggtggattg agttttggtg gatttatcat tactgttgtt
    32641 ttgctttttt tcgtattcag tgccaaccga tttttcttga atagaaggca aaaggaaata
    32701 ggcatctatc agctttttgg tatgaataaa ctgcagatat caggtatata tgtgttagaa
    32761 atcatgataa ttggattgtt cgcctgtatt tctgggatat tactcggtat tattttttcc
    32821 aaactctttt caatgatttt ggttcgaatg atggatatgg atcttactag tccatttttt
    32881 atctccattc catcagtagt agatacttta tttgcttttt tcatcatcct tttagcagta
    32941 tctgtatatt caatatggaa aatatggcgc tatccaatga ttcgaagttt tggagaaaaa
    33001 gaacaagcag atagttcaac aatgcgcttc aggacaaggc accgattact cgcagtcatc
    33061 gggttactac ttttaacgag cggatatttt ggagctagtc attttaggga aatcacttca
    33121 tggatgatca gttatcatta tcttgataca ttagttttct tttttccttt tttaattttt
    33181 ttcgtttgtg tggtcggtac ttatttgttt ttctgttata catttcggtt atttttgatc
    33241 atattgagta aatggaagat ttattactat ggtatcaatt ttttgataat gggtaacacg
    33301 caagttcatt tgctcaaaag ttggcgtaca aattctctga ttacagtcat tctcggaatt
    33361 tctttaatga caattggcgg cacggctagt atctctacta ttttatccta ccaggagaaa
    33421 gtttcctccc cgatggacta tcagtttgat gttgagacag agaaaaaaat caagccgatt
    33481 ctagcagagg aagggcagaa gataactaaa gaaatcacct tgcattataa agtcattggg
    33541 agtatctata gtcaaaatct cgaagaacct atgtttcaaa ctgctaatct gatcacggaa
    33601 acacaatatc aagccttcag aaaagttaat ccagatttgc cgaacatttc tttgaaatca
    33661 cctggtcata ctgttttgct tgatcaaatg caaactcttt ttcggaatat ttcattatat
    33721 ggatctagta ttggactgcc agataatcaa gaattgaaga ttcaacaaat gcttccaagt
    33781 gtattaggtg acgaaacaat ggtatatcta agtcctgtac tgattgtaga tgataccgtt
    33841 tttgaaaaag caaaaggtgt ggattatcaa gtagtcaatg tagatgtatc aggtggaaat
    33901 aatgaaaaaa tagatgaacg actgagcaat gacctgtcga taaagtggct caatgctgtt
    33961 tattattctt atgatatcgt aaatggaagt ctacaaggag aaattagcac aaagaaactt
    34021 ccggatgacc aaatgaagga agcacaattt agccaagaaa gctctcgttt gaatttctct
    34081 tccagctatt cgaaattgcg tgcagttaat cggcgaatcg gtatcaatat ttttgtcaca
    34141 ctatttgtcg ggatgatcgt gattattgct actggtagta ttttgacagt ccggcaatta
    34201 gcagaagcag aggaagaaaa agaaaattat cacctattga ctaagctggg gattccacaa
    34261 agaaggatca gacggatgat cttcgagcaa aacgcactta ccttctttcc acccatgata
    34321 ttagggatca ctcacgcagt atttgcaatc aatgtcttca ctcagtatat aaaaactgcc
    34381 gattactggt tggcttatct tgtgagtggc ttattgatcc ttatctatct tttgctttat
    34441 gtcattacga gtcagttata ttgtcggatt atcgaggaat gatatacgga ataagacaag
    34501 ataataaata gaactaaatt ttgaatacca tttatttgga ataagaggtt gtgacacgat
    34561 ttttgtcaca acctctttat tttttatatt ttttaaaagt acgagaaatt ataaagaaaa
    34621 aagcagtgat ttgatgtgct atttttataa aagctatgtg acaaaactgt tagtaaaaaa
    34681 acggtttctg taagctagac acatgtttct ttttgtcaaa attagttaca ctttgtgtga
    34741 ggttatatga ggagggaatc caatgaacaa atggcgttct aatccaaaat tgaattattg
    34801 gggaaaattc atcattcgaa caatttttta tagtgcagta ctgctgttcc tgatttatct
    34861 gtatcactat aaaaatattc aaggaggaac ttttatctat aacgaatttt aggaggaaga
    34921 gtatggaaat caaaacgatt attgaagcaa tcgatgattg gggaataaat gaacctgatc
    34981 gagttgctta tcaggcggat gagacgcata cttttggtga attgaaacaa gcatcagacg
    35041 cacttgctta ttatttagaa aaaaaggtag aaggcgatgg accaattgtc gtttttggca
    35101 atttggagtt tgaaatgatt gtctcatttc taggggttgt caaatctggc catgcctatt
    35161 tgccgattga agagcataca cccaaggagc gtatcctatc gatctttcgg gtggctaaac
    35221 catctatggt catcagtatc ggggactgga tagaagatat tccttcggtt cctgtcataa
    35281 caaaaaaaga atttcaagaa atcaagaaga taccagtagg attttatccc agaaatagcg
    35341 taaaaggtac agaaaatttt tatattattt ttacttctgg tactactgga gaaccaaaag
    35401 gcgtacaaat cagtcatgat aatctagtca gctttgttca atggacgatg gaagactttg
    35461 ggatcaagcc tggtatgcat ttcttagccc aagcgccatt ttcttttgat ttatcggtat
    35521 tttctattta tcctgcatta gtttctggcg gaatgctgaa gccgttaaat aaagcagttg
    35581 ttcaagactt tcgtcaatta ttcgcgacat tgccagcctt gaagttgaat gtgtgggttt
    35641 ctactccatc atttatggat atttgcttga tggaacctac attcaatgga gaaaatgtgc
    35701 cggaattgga catgttttta ttttgcggag aagaattgac gaaaaaaact gcagaaagtc
    35761 tacttgatcg attcccaaat gcacggatat ataatactta cggtccaaca gaagcaactg
    35821 tagctatttc aagtattcag attgaccagc atgtactaga tagttatgac cgactaccga
    35881 ttggctacgt aaaaaaagac acgaaagttt ctattgtcca agaaggtaaa cctgtttcaa
    35941 aaggagaaac gggtgaaatc attattgcag gaccaagcgt atcaaaaggt tacctgaaca
    36001 atcccgaaaa gacagctgct gcgttctttt gtcaaaatga cttagcaagt taccatacag
    36061 gggatgcagg tagactagat gaatatgggc ttttatttta tgaaggacgt atggatcagc
    36121 aggtcaaatt acatggatac cggattgaac tcggggatat cgaacattat ctgctccaag
    36181 acaaccgaat caaacaagct gtcgtcgtac caaaatacca aggaacaaaa gtacagcagc
    36241 tggttgcttt tgtcgtatta gaaaacaaaa cgaaacagcc ggattttcag ttgactaaat
    36301 ctatcaaaga acaattacta gaagttgtaa tggattatat gattcctcag aagttccatt
    36361 atgtcgatct gctgcctcag acagttaatg gaaaaatcga tcgaaaaaaa ttaacagctg
    36421 aggtgaatcc tgaatgatgt tacctcatat gatcccttat gcagagccgt tttatttttt
    36481 tcttttagcc attgcgcttg taccgatcgt tctatcttta ttgatatggg aaaaaagatt
    36541 accagtttat caatcagcag tgacactttt ctttttattt gtcagctttg gaggtaatta
    36601 ttggcaacag ggagcggcgc tgattgggta tgttttgtgg cagacgatac ttgtatgggg
    36661 ctattttgtt tatcggcaaa ggaaaaatca gacaggatgg ttttttgccg ccgttatttt
    36721 agcgataatt ccactgtttt taacgaaagt gactcctttt tttgaacatg gaaaagcatc
    36781 gttacttggt tttttaggaa tctcttattt aacctttaaa tctgtacaaa tgatcatgga
    36841 aataagagat ggcatgatca aaacatataa gccatttcgt tatatccagt ttctgctgtt
    36901 ctttccaaca atctcttctg gaccaatcga tcgctatagg agatttgaaa aagatcagct
    36961 ccatccgcct gttcgtgata aatatgttga tcttttggga aaaggcgtcc aaaatatttt
    37021 tgtcggtttt ttatataaat tcattatcgg ttattatttt ggtcaagtac tgcttcctgt
    37081 agtgggacgc attgccttac agcatggtgg tatttcatgg gcattagtag gttatatgta
    37141 cgtgtacagt atgtatttgt tttttgattt tgctggctat agcttatttg cagtcggtac
    37201 aagctacatg atgggatatc agacaccaat caatttcaat aaaccttttt tatcatggaa
    37261 tatcaaagaa ttctggaatc gttggcatat gacgctgtcc ttttggttcc gtgattatgt
    37321 atatatgcga ttgatgttct tcatgatgaa gaaaaaattt tttaaaagca agatcgtaat
    37381 gtcaaatatc ggttattttg ctttgtttct tctaatgggt atatggcatg gattgacgtg
    37441 gtactacatc gtatatggac tgtatcatgc ttgtctgatc tgtctgacag atgcatggat
    37501 ccgatttaag aagaagcata aagagcagtt gccttctaac aaatttacgc atggcttagc
    37561 cgtatttttg acatttcaag cagtatgttt tagcttcctg attttttcag gatttttaga
    37621 taaacttttt tttagctaac gaatagtgac atattaattt atataacaaa ggagaaaagg
    37681 aaaatggaag aacaaatttt atcaatctta gaagaaataa caggaacaga tgaagtaaga
    37741 aaaaatcgtg atattgatct atttgatgaa gggttgcttg attctttagc atctgttcaa
    37801 ttattagtcg agctagacgg agagctggat atccaagtcc ctgtatctga attcgagcga
    37861 gaggattgga gcacaccgaa taaaatcatt caacaagcaa ctgcattgaa gggttgagta
    37921 tgaaaaagaa actttttgct attttcggcc cggttgtttt agctgttggc ttactgtttg
    37981 tgttttttac ctcctcctat caagtagata tctctaatcc agaaacgatt agacgtgcct
    38041 cttcttccat gtcagtgaac gtgttgaaag gagatgcgat aaaaaattat gcattatctg
    38101 aaaaacaata tattcctttt tttggctcaa gtgaattaag cagaatcagt ccatttcatc
    38161 cgtctgttct ggcagaaaaa taccagcgaa actatcgtcc atttttgctg ggagcacccg
    38221 ggacacaatc gttaagccaa tatatgatga tgcgttctgc aggagatgct atgaaaaaca
    38281 agaaagtcgt ctttattatt tctcctcagt ggttcgttaa aaatggtgta aaaactgatt
    38341 actttaatac gtattattct gaacttcaaa catacgactg gttgttttca atgaagaaag
    38401 taacgcctgc tgatcgctat ttagctagaa gattattaac tttctcaaaa gtaaaagaga
    38461 atgatacgtt gacggcgatt ctgcaaacga tcaaaaaagg gaagctacct ttacctgaat
    38521 ctttgaatca gctgcgcagc caatggaaca tgctgaagag agaggatgaa gtattcagca
    38581 atattgggtt gaaagatcga cagcaaaaaa tcgatcatga gtcaaaacga ttaccaaaac
    38641 aataccaaga aacagaatta tccattttag caaatcaaat tggagaacga gaaacgacga
    38701 ataatccatt cgggttgaaa aacgattttt atacgcatcg tatccgagcc cacgagccag
    38761 agctcaaaca gtcacaaaaa aattgggatt atcgtttttc gccagaattt tctgattttc
    38821 agctggtctt ggatcaatta gcaaaaaacc ataacgaagt attgttcatc atcccaccgg
    38881 ttaacgagaa atggagcgat tataccggac tatctcaaga aatgttacaa ggatttgcca
    38941 aaaagatcaa atttcaatta aatagccaag gattcaatcg aatagctgat tttgtcaatc
    39001 aagcgggtac caactatttt atggaagaca cgatccatct aggctggaaa ggctggttgg
    39061 ctgcagatca acagatcaga ccgtttttag aagaaaatca tattactgct agtaagtatc
    39121 atcttgacga tgcttttttt agcaaatctt ggcaacatca aataccagat aaactacaat
    39181 taaaataaag aaaacaggcg agtgttgctc gcttgttttc tttatttttg aatattctga
    39241 ataaaagata aaaataccaa gtttgcctga acaaaaatca taagcaatgg tataatcaca
    39301 atatgaatat agaaatgggg gaaaacattt ggatacaaaa gaagaacagc tacttattga
    39361 tttaacttct gcaaaaggag tacctggaaa tgaagaagag gtaagagaag tattcagaga
    39421 atatgccaaa ccattcgctg atgatatttt ttatgacggt ttaggcagtg tgattgccaa
    39481 acatggtgct ggcggaggcc ccaaggtctt tatttctgga catatggacg aagttggttt
    39541 tatggtaaca aaaataaccg aaaaaggatt cttggaattc caaactcttg gaggttggtg
    39601 ggggcaagtc atgcttgctc agcaagttga aatcaaaaca cgtgaaggga aaatcgtcca
    39661 cggtgtgatt ggttccaaac caccacatgt tttaacacct caagtaagaa ataaacctta
    39721 tgaaataaag gatatgttca ttgatattgg cgcatcaagc caagaagaag ccaaagagtg
    39781 gggcatacgt cctggagata tggtcactcc atatattgaa tacaaacgaa tgaatggcag
    39841 taaatattta ctggcaaaag catgggataa tcgtatcggg acagctgttt ctctgcgagt
    39901 attagagaat ctatctaaag aagcacaccc aaatgtttta ttcgcaggaa gcgatgtgca
    39961 agaagaagta ggcttgcgag gtgctcgaac aagtacacac cttgtaaatc ccgatattgc
    40021 ttttgcttta gatactggta cagcaggaga cactccagga atgacaccaa aagaagcaga
    40081 ttcgatttta ggaaaaggcc cacagatttt gatttttgat gcatctatga tcccgcataa
    40141 aaaattattg aattttgtta ttgatgtagc agaggaaatg gatattccat tccaatatac
    40201 agtgatttct ggcggaggaa ctgatgcagg acaaatgcat ttgacaagag atggtgttcc
    40261 gtctgtagcc attaccgttc ctgttcgtta tctgcattcc catacatcag tgattcatga
    40321 agatgattat ttgaatacag tgaaactagt cacagaatta gtgaaacggc ttgatagtga
    40381 aacagttgaa aaaattcgga gttatgaata atgaataata gaata
//
LOCUS       DAXLPY010000019        37689 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.019, whole genome shotgun sequence.
ACCESSION   DAXLPY010000019 DAXLPY010000000
VERSION     DAXLPY010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.019"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(109..2445)
                     /locus_tag="ACF3UF_001110"
     CDS             complement(109..2445)
                     /locus_tag="ACF3UF_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFD3671256.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTDHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSD
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            2587..3255
                     /locus_tag="ACF3UF_001111"
     CDS             2587..3255
                     /locus_tag="ACF3UF_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3671257.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     HIELIITDVMMPEMDGYDLVGSLRNARFDMPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSILTIGQTKLELDTYTVVQNQHSFILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            3258..4298
                     /locus_tag="ACF3UF_001112"
     CDS             3258..4298
                     /locus_tag="ACF3UF_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3671258.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRVIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFLQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQVNGKIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAIIRLSK"
     gene            complement(4538..5419)
                     /locus_tag="ACF3UF_001113"
     CDS             complement(4538..5419)
                     /locus_tag="ACF3UF_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3671259.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITDFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            5579..6307
                     /locus_tag="ACF3UF_001114"
     CDS             5579..6307
                     /locus_tag="ACF3UF_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFD3671260.1"
                     /translation="MPTGVLINVGSVLLGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            6464..6781
                     /locus_tag="ACF3UF_001115"
     CDS             6464..6781
                     /locus_tag="ACF3UF_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3671261.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            6774..7382
                     /locus_tag="ACF3UF_001116"
     CDS             6774..7382
                     /locus_tag="ACF3UF_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFD3671262.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            7437..8228
                     /locus_tag="ACF3UF_001117"
     CDS             7437..8228
                     /locus_tag="ACF3UF_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFD3671263.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADYELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            8366..8854
                     /locus_tag="ACF3UF_001118"
     CDS             8366..8854
                     /locus_tag="ACF3UF_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFD3671264.1"
                     /translation="MKAEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            8905..9777
                     /locus_tag="ACF3UF_001119"
     CDS             8905..9777
                     /locus_tag="ACF3UF_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFD3671265.1"
                     /translation="MREKRAFYINGYAGIVGLIVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            9953..10315
                     /locus_tag="ACF3UF_001120"
     CDS             9953..10315
                     /locus_tag="ACF3UF_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3671266.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            10324..11076
                     /locus_tag="ACF3UF_001121"
     CDS             10324..11076
                     /locus_tag="ACF3UF_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671267.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            11090..12892
                     /locus_tag="ACF3UF_001122"
     CDS             11090..12892
                     /locus_tag="ACF3UF_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671268.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAEKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQTTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            13168..14208
                     /locus_tag="ACF3UF_001123"
     CDS             13168..14208
                     /locus_tag="ACF3UF_001123"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFD3671269.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSLDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(14260..16410)
                     /locus_tag="ACF3UF_001124"
     CDS             complement(14260..16410)
                     /locus_tag="ACF3UF_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3671270.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQTADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFEPVPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNN
                     NNGSNNSNNNNNNSNNGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPN
                     TANQSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFEHLGKPYVWGAKGPN
                     TFDCSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVG
                     IYIGNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPATSGSLTGSSILDGLDGS
                     FHFSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLF
                     GIKGSYNGSSVTFNTHEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDF
                     YKPTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEA
                     NAEILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQ
                     IPETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(16767..18140)
                     /locus_tag="ACF3UF_001125"
     CDS             complement(16767..18140)
                     /locus_tag="ACF3UF_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3671271.1"
                     /translation="METTMNPEQMVLYEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRDNMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(18140..18535)
                     /gene="rbsD"
                     /locus_tag="ACF3UF_001126"
     CDS             complement(18140..18535)
                     /gene="rbsD"
                     /locus_tag="ACF3UF_001126"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFD3671272.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(18563..19480)
                     /gene="rbsK"
                     /locus_tag="ACF3UF_001127"
     CDS             complement(18563..19480)
                     /gene="rbsK"
                     /locus_tag="ACF3UF_001127"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFD3671273.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(19589..20602)
                     /locus_tag="ACF3UF_001128"
     CDS             complement(19589..20602)
                     /locus_tag="ACF3UF_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFD3671274.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQISHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEESGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(20683..21282)
                     /locus_tag="ACF3UF_001129"
     CDS             complement(20683..21282)
                     /locus_tag="ACF3UF_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFD3671275.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILSNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTNN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHVVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            21467..22168
                     /locus_tag="ACF3UF_001130"
     CDS             21467..22168
                     /locus_tag="ACF3UF_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671276.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            22178..24889
                     /locus_tag="ACF3UF_001131"
     CDS             22178..24889
                     /locus_tag="ACF3UF_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFD3671277.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNAKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            25410..27038
                     /gene="treC"
                     /locus_tag="ACF3UF_001132"
     CDS             25410..27038
                     /gene="treC"
                     /locus_tag="ACF3UF_001132"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFD3671278.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(27098..28279)
                     /locus_tag="ACF3UF_001133"
     CDS             complement(27098..28279)
                     /locus_tag="ACF3UF_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3671279.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSVW
                     LVPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYQNSSFSEEDYF
                     K"
     gene            28531..30054
                     /locus_tag="ACF3UF_001134"
     CDS             28531..30054
                     /locus_tag="ACF3UF_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFD3671280.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVASI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFITQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYIEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEALLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(30123..30851)
                     /locus_tag="ACF3UF_001135"
     CDS             complement(30123..30851)
                     /locus_tag="ACF3UF_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFD3671281.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(30864..32144)
                     /locus_tag="ACF3UF_001136"
     CDS             complement(30864..32144)
                     /locus_tag="ACF3UF_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD3671282.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIALSAFLSALLAFCFKKTLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLVVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(32285..32887)
                     /locus_tag="ACF3UF_001137"
     CDS             complement(32285..32887)
                     /locus_tag="ACF3UF_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFD3671283.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            33132..33338
                     /locus_tag="ACF3UF_001138"
     CDS             33132..33338
                     /locus_tag="ACF3UF_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671284.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            33650..34369
                     /locus_tag="ACF3UF_001139"
     CDS             33650..34369
                     /locus_tag="ACF3UF_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFD3671285.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(34450..35133)
                     /locus_tag="ACF3UF_001140"
     CDS             complement(34450..35133)
                     /locus_tag="ACF3UF_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFD3671286.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            35379..37565
                     /locus_tag="ACF3UF_001141"
     CDS             35379..37565
                     /locus_tag="ACF3UF_001141"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFD3671287.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        12365 a         6652 c         7543 g        11129 t
ORIGIN      
        1 attaaaaaaa acagcgcgaa acaaggaaca tattacttcc tcgtttcttg ctgttttcta
       61 ctatttcagc gctcttatga ctcaaatcta aatgtggttg tcacaacctt attctgcacg
      121 caaagcgata gcggcgtctt ttttcgctgc cattcgtgca ggaagatgac cgccaagcat
      181 cgtcaatata gtagagacga tcactagaat aatcgcatgg acaggattta gttgagcaac
      241 attttttaga tccgtcatgt tgtataagat gctattgata gggaatgtag ctagccatgc
      301 aataaacaca cctaatatcc cagaagaaat acctaaaata cacgtttctg cgtcaaatac
      361 gcgagtgatg tcttttttac gtgcacctaa agcttttagt acaccgattt cttttgtccg
      421 ttcaatcaca gatgtataag taatgatact gatcatgatc atacttgtta ctaaagagat
      481 ccctgcaaaa gcaataagga cataagtgat agcatccatc aatccgccag tcagttcagt
      541 catcgttcca gctaaatcag tataaatgat tttatcttca tctgatttgc ctttattgta
      601 atcatctaga taatccaaga tcttttcttt gtcttcaaaa ttgttcggat aaatcatgat
      661 acttgaaggc aagctgtctc cacctaaata actaagcaat gtttgtttgg cattttcgtc
      721 aactttttca gtagttaaga catttacatc actgtctctt tgagctttga cgatttctga
      781 ttctttgttt tcgttgacga tttgagtcgt taattgatcg ctataagcga ttcctggaga
      841 taagagattc attgtagaag aagatttcac gcgtaggatc cccgagatct tcaattcatc
      901 agaagcattc tgatacatcg catcataatc tgtattaggg ataaaattcc cagttggaag
      961 ttttgtatag taagtattgt tgtttactaa tttgaatgtt gtaccaacga tatcatcaaa
     1021 atcaagtttt tcgtcttctt tcacatcaaa tccaagattc ttcaatgcgt tgatattagt
     1081 attattattg ccgtctacga tcagcacgac atctgttgct gaggctggat aacttccggc
     1141 aagtaaagaa taattgtctt ttaaaaagtt ttctttgcta gtgtcaagct gtgtagggaa
     1201 acttgacact cccacacctg tcattgctga catcgtacta gataaagaaa gagattccgt
     1261 atcaggattt tgattcgaga agctgacagg ctgtactttg ccatttacat cacgtaaaag
     1321 attgattcct gtagtacggg taaatccgat attattactt aagttaggat cgatgtctgt
     1381 tacgtaatcg acgtatgttt gatcaatctt attcgtgtgc tgtgctttat cttcttcgct
     1441 gacttttgca gtaatcgttt tgctgtctgg ataatccgct ttgcttgcac ccaatccggc
     1501 atcgtcacga gtctggttag tcgttacctt agaaatagta atcggaaatt tcgccatcgt
     1561 ttcagcttgc gtgttatcga tttgtttttg gaatccagaa gaaagggaca gaacgatcgc
     1621 gattccgatg atcccaatac tggaagcaaa ggaggtcaag aaagtacgtc ctttttttgt
     1681 tcggatattg ttgaaggaaa gcttcaacgc tgtccaaaaa ctcatctttg ttctgcgtaa
     1741 gttaaattga tcatcttttg gccgttcgat gtgaggatgg gaatctgtta agatcttacc
     1801 atcagaaaat tcaatgatcc gatctgcgta ttgatgggcc agttcaggat tatgtgtgac
     1861 catgatcact aatttttctt tcgataactc ttggatcaat tccatgatct ggatacttgt
     1921 ttctgtatct aacgctccgg ttggttcatc gcacaaaagg atatctgggt cattggctag
     1981 tgctcgagcg atggccactc gctgcatttg tccaccagat aactgatttg gctttttatg
     2041 catatgatct gtcaagccga cccggtgcaa tgcatcttct gcccgttttc gtttttcgtc
     2101 tttagaaaca ccacttaatg tcatcccaag ctcaacgttt tcaataatgc ctagatgacc
     2161 aatcaagttg taactttgaa aaatgaaacc gatagagttg tttcggtagg catcccagtc
     2221 actgtcctta aagtctttag tagactttcc gttgattacc atatcaccgg aatcataatt
     2281 atctagtcca ccaatcacat tcagcatagt cgttttacca gaaccactag gacctaaaat
     2341 cgctacgaat tctttttgtc tgaaagcgac agacacacca tccaatgctt tggtggtggt
     2401 ttcgccgact ttataatatt tttttatatc ttttaattga agcataatca cccttctccc
     2461 gtattgaaat attcggtata ctaataagta tatcagaaca atgatcgtag tatacgaaat
     2521 aaatgttaac tgaagatgaa ctacaagaaa aaatctagaa atttttcaaa aaacagaggg
     2581 agatcaatga atcgtatttt agtagtagaa gatgatccgc aattacagtt gctttaccgt
     2641 tctgtgttgg aacgagcggg cttttcagtc atcaccgcac tgaatggaga ggatgcgctg
     2701 aaaaaactag aagcgacaca tatagaattg atcattacag atgtcatgat gcctgaaatg
     2761 gatggctatg acttggtagg atcattacgt aacgccagat tcgacatgcc agttctgatg
     2821 attacagcaa aggctgattt cgaggacaag aaacgtggat tcaaattagg tgcagatgat
     2881 tatatgacaa aacccatcga tgtcaatgaa atgatcctgc gtgtggaagc attgcttcga
     2941 cgttcaaaaa tcaattacag cagtatcttg acgattgggc aaacaaaatt agagctggat
     3001 acttatacag tggtacaaaa tcagcattct tttattctgc ctcaaaaaga atttctgctt
     3061 ctgtataaat tactgtctta tccaaacaag attttcactc gccagcagtt gatggacgat
     3121 atttggggat tagacacgaa tacagaagaa cgaacgatcg atgtacatat caaacgttta
     3181 aggacccgtt ttgaaaagac agaagatttt caaatcatca cagtacgggg actaggctat
     3241 aaggcggtta tttaaagatg aaaaagaagc tattttcaca attatggatc tattttgcta
     3301 gtatcgtatt tatttcgatc ttagtaacac tgctgtgttt tcttggtttt attttcttat
     3361 tgtctcgaca ttctatctcg cctgctgaat cggctggaaa accaacgtta tacccgttat
     3421 tcgtctttgc ggggttcagt atggtcgtgg gtacaggaat atcgattttt gttgggcggc
     3481 gtatcctgca tccaatcagt gcgctaggga caaatatgag tctggtagca acgggagatt
     3541 tttcgattcg aatggatgaa cagcagaaag tagcagaagt acagcaactg tataaagatt
     3601 tcaacgttat ggtccaagaa ctcaatagta tcgagacact gaggaatgac tttgtgtcca
     3661 gtgtatccca tgaattcaaa acaccactag caacaatcca aggatatgtt caattgttac
     3721 aagccccaaa tctttctgac gaagaacgcc aaatattttt atatcgggtc atcgaaagta
     3781 tcacgcagct ttcacaatta acagagaaca ttttaaaatt aaacaaactg gaaaaccagc
     3841 gtatccaact ggaaaagaaa gagtatcgat tagatgaaca aatcagagaa gtaatcgttt
     3901 ttttgcagcc taaatgggaa aaagaacagc tagaattgga tatcgaactt gctgcagtaa
     3961 actatacagg taatgaagag tttttgtacc aagtgtggct gaatatcatg gataacgcca
     4021 taaagtacaa tcaagtcaat ggaaagattc atatcaaatt atttgagaca gccacagaga
     4081 tcgtactgga agtgaccgat tcaggtgtag gaatgaatga agagacccga gatcgaatgt
     4141 ttgaaaaatt ttatcaagga gatacaagcc gtcagatttc tgggaatgga ctagggcttt
     4201 cactggtcaa aaaaattcta gaactacatg atggacgtat cgattatagc agtatcgaag
     4261 gagtagggac gacagcaata atacgtttaa gcaaataata ggaaaaaaga acaaaatacc
     4321 taaaaattct agtgaaggtt tttagggatt tttagacgtt tttttgtgat tagcgaattg
     4381 ctcttaatgt tcttccggca taaaatcgct gatcttctat tgaaatacga gaaacgttag
     4441 atgtgtcatt gaatcaatgg cacgatgtaa gaaagagagc gaaagtcatg cgtcgctctc
     4501 ttttttgggg tggatagatg gacagaaaat gtagggctta gttttcttct tgatttaaat
     4561 actcccaaaa tgtatctgaa gccaaagaat gctcaccgac tttacgagta aatgcaagat
     4621 aactctctgt tgttggagaa atagggagaa tcacagtatt ttcttttaat agattcttga
     4681 ctgttttttc cataacaata gcaatcccca tgtcatttgc aatcatattg atgatcaagt
     4741 cgattcttgc tcctttataa gagatttttg gttcaaatcc agcttcgcga cacagatcta
     4801 gtacaggttg atacaagttc gtagtggggc caagtagcaa aaagttctcc tttttcagtt
     4861 cgcttagatc caatttcttt ttactagcta aaggatgatt tttaggtaga actgctacaa
     4921 aatcgtctgt ttcagtaggc aaccactcaa tcgaactcgg cggggcctgg aaacttctag
     4981 caaagtggat cgtgtcacta tgttcattgg cgtcattgta agttaattcg acactttcca
     5041 cttctttcaa ctggactgta aattcaggat ggcgtttcaa aaagtcggtg attttggaaa
     5101 aacctttata attgatcatt gtcggtatcg ttaagatatt taatgaaaga ttgttgtctt
     5161 tcgtataggt ttcaagcact tcttgcatag catggtattg ttctacgaca ttttttacat
     5221 atgggagcaa taagcttcca gcttcggtca attcgatttt tctatgggcg cgttcgaata
     5281 atttgacgtc taattctgtt tctaacgaaa gaatctgttt agaaatattt ccttgggtgg
     5341 tgaattgtcg atcagcagtt ttggtgaaat tcattgtttc ggctaaatca agaaaaactt
     5401 cgaatttatg gatatccatc atattcctcc tacttattcc aataaagaat actttaacac
     5461 aaaaaatgaa ttggtgtaat cttctctgtc tgttacaatc tttcttgcag cgaaagcaat
     5521 aattacagaa atttttctga tttttttcgc ttcgtagaaa aagagaggag tttttttgat
     5581 gccaactgga gttttgatca atgtaggttc cgttttgctt ggcggactaa ttggcggatt
     5641 agtaggaaat aaattaagtg aacattttaa agcacagctg acgatggttt ttggtgtgtg
     5701 ttcgatgggg atgggaatct attccattgc gccgatgaaa aatatgccgg ctgttatttt
     5761 tgctttagtg ataggaacag cgattggtct gattgttcat ttaggtaatg ggataaataa
     5821 gggggctgcg ctgatgcaag tacctatttc taaaatcttc cctagtgaaa agcttggtat
     5881 gacccacgat gaatttatca gtacattagt gacggtcatt gttctatttt gtgcaagtgg
     5941 tacggggatc tatggaagtt tagattctgg aatgacagga gacagtacga ttttgatttc
     6001 taaatctgtc cttgattttt tcacagcagc tatttttgcg tgtaatttag ggtatgtcgt
     6061 ttctgtgata gcaattcccc aattcattat tttttatatt ttgttcttat tggcaaaatt
     6121 tatttatcca ttgactacac cagacatgat cttagatttt aaagcttgcg gcggattctt
     6181 gatggtcgct accggtttta gaatgatcaa cgtgaaaatg ttcccagtag ctgacatgat
     6241 acctgcaatg atcgttatca tgccactgag ctggatgtgg acaaattgga ttatgccact
     6301 gttataataa aaatcaaaga gaagccattt ttttgctgac taaaaaggat caaatctttt
     6361 agtcagtttt tttgtatttg acaaactgat tttgaaacta tattatatgt tgtataatat
     6421 agattgaaat aaaatattac acttgagaat agaaggtgac gtaatgcaca tccagattcc
     6481 aactgttctt cttgatggta ctgtgttagc agcattaagc aaggaagata tgtatgggta
     6541 tgccttaaca aaaatcgtac aagaaagtct ctctgtcagt gaatctacac tatatccggt
     6601 tttgagaaga ttgaaaaaag aaggatatct tgagacctat gatgaacctt ttgaaggcag
     6661 aaaccgtcga tattactcgt tgacaccaat gggaagtcgt catttagaag aaattattga
     6721 tgaatggatt gtttttcgag attctttaga ccggttattg gaggagagca caaatgaatg
     6781 aatatttgaa tgaagttgtg gatcatcttc aagaaattcc tgaagacgat cgttttgatt
     6841 tgatccagta ttatgaggaa tattttttag attctggaaa aacattagat cagatcattg
     6901 atgaatatgg tacaccaaag cagtttgcct taaaattaaa aatcagttac ttttcagaag
     6961 aagaacaagc agaaaacgag ttagtgaaaa atccaaaaag acaaattcgc ctgatttggt
     7021 taatcattat cggtttattt gcttctcctg tcctcattcc actagcactg gggtttatat
     7081 tggttattgg gggactattg gttgctttac tagcgctcat ttttagtatc tatgttttat
     7141 gtatcagtat cttaggtgtt ggcctattca tgatcatatc aggaataagt gtgtttggac
     7201 aatcgattct gagtggatta ttctttatcg gtgtcggtct gttcgccaca ggaagcgcag
     7261 tatttatttc gccactgttg ctgaaaggaa caaaagggct tttttatgtc atgatgaact
     7321 ttgttaaatg gatgggacga cgttttatta caaaaagaga tctgcattca gcgggcgttt
     7381 gaaggaggac acataaattg agattgaaac attttttgat taccggtatt ggtctgatgc
     7441 ttactggtgg cctcctagca ggtgcaactt atacattagg cgctcaaaag agtctgactt
     7501 gggataatgg tcctcggttg atcgatatgg ttactgagac aaaaaaaatc aaggatgcaa
     7561 acaaaatcgt catccatgca gaaaatcaaa cagtttcggt catacgcgga ttggattttg
     7621 agataaaaac gacttatgat aagacagaaa agccagaaat aaaggagaaa aatggcgtgt
     7681 tgactgtgaa tgcagtcaaa aaatcaacag gtgcaatcat tagtttagaa gacacaagtg
     7741 cacaaatcac tattgttgtc cctgcagatt atgaattatc tgaattgaca atcgaaggga
     7801 ataatagtgc aattgatatc aacgaagtat caatcaaaaa agtgaatact aagacacatg
     7861 atggctgggt atcgttcaat gaatttacag gaggaacaat aactgcgaaa gatgaattag
     7921 gctcacttcg actagatgag gccaatgtgg ataacttgat cgtcacaggt gaaaacagca
     7981 acttccatct agaagacagt ttgatcagca aagaaggaaa agtcatccta aacggtggta
     8041 atttatcttt gcatgagatg gaaaacagtg gctatactat ccaaacgtct ggtgaatctt
     8101 atattgaaaa agactaccag ccaataacaa atactttgtt agaacaagga cagaaaaagc
     8161 taaagatcac tgctaaagac acatcgatca atattacgac ggatcaagag gacaatgaaa
     8221 cagattgatc ctgtactcaa ctagatattt taagaaaaaa cagcaaagat ccttccaatc
     8281 tttgctgttt ttcatcgctt aacgcacata actatagtaa aataagaaag aaaatatcta
     8341 taaagaaaac agggtgaaaa agtatatgaa ggcagaagaa ggtcaaagag aaaagttaaa
     8401 gacagaaatg gaaagattac atacttatat cactcaacta agccaaacct tctatgatcc
     8461 agacaaagaa aaagtgatgg ttaattaccc gaacaattca gaaggtcgcc aattagagca
     8521 agtgtaccat gaagttttca aacatttatt gacggtgaag aaagagctgg attattattc
     8581 tttaccgatt atcgatacag gaatattgaa gtatgatggg aagaaggaac gatttatctt
     8641 taaatctgtt cgggaagatt tgcctctttc agcagggatg gatctagagg tcttggtaga
     8701 agactatttt acagaagaaa agcactgggt tcgaacaaaa ttggattatt taccgcaggc
     8761 agccggaggg acacaggcaa gcggttggta catcactgaa gacaaagagt tagaactaga
     8821 aggtgtaatg gcgcgtattc gaaaaaaaaa ttaaaaaagt aacattagat atttattgaa
     8881 ggataaagga gcgcaggaag tagcatgaga gaaaaaagag cattttatat caatggttat
     8941 gcagggattg tcggattgat cgtattagct ttagttggat tgtttttctt ctatttaggc
     9001 atgtggcaag cgaaagtttg ggcacttttt ttaagtattt ttctttggtt gatcacgtta
     9061 ttgttgttaa gttcggcaac tgtagtcagt cctaatcaag caaaagtaat tttgtttttt
     9121 ggacaatatt taggtacgat tcgagaaaat ggctttttcc ttacgatacc tttggcacaa
     9181 aaaatgactg tttcgttgaa agttcggaat ttcaatagtt ctgttttaaa agtcaatgat
     9241 ttggatggaa accccatcga aatctcagca gtagtagtct ttaaagtcgt tgatacagca
     9301 aaggcattat tcgatgtagc gtattatcaa gattttgtag aaatccaaag tgagacagcc
     9361 attcggcata tcgctagcca atacccgtat gatacattca atgagaatga tttgacgctt
     9421 cgaggaaaca cgacggcagt gtctgacgag ttgcaaaaag aactgcaaga gcgtttagca
     9481 gtagcaggtg tcgaagtaat cgaaacacgc ttgaaccatt tagcctatgc aacagaaatc
     9541 gctagtgcca tgctccaacg tcaacaagca aaagccattt tgtctgctcg acaaaccatt
     9601 gttgaaggag ctgtcacaat cactcaaatg gccttagagc aaatcgaaga tggacaagaa
     9661 atcaatttca ccgatgatcg gaaagtccaa ttgatcaata atttacttgt ctcaatcatt
     9721 acagacaaag gaacgcaacc tgttatcaat acaggcgaca tgaaagaccg taagtgacat
     9781 actttttgta agataggaag aaggagttta ggacggatta ttgtcttgaa ctcttttttt
     9841 agttgtttta aagaaaatga caaaattgaa agaagaatga tagttgattc gaaggcagaa
     9901 ttgttcgctt ttttctataa tcagtatata aagtaagaga gaaggggaaa aagtgaaaaa
     9961 acttctgatc ggtctacttg ttttcatcgt tgtggtactt gcaggggtga aaatcgcaga
    10021 ttacgtagtt atgggtggag aagaatacta tgtacaaatt acgacagatg gtacaaaaac
    10081 agtttcaaaa tcagactctg gacaagaaac agtcaactat agatatatcc tgcctggcta
    10141 tacgaaagag ggtaaggaaa aagaactgga cttcaaggga caattgactc gaccgcttcg
    10201 taaaggagca tatttaaaaa tcacctggaa caaaaataaa ggtgtcactt cgtatgaaga
    10261 agtcgaaaaa aaagacgtgc cgaaaacagc actggaaaaa ctaattaaag ggtagggaaa
    10321 gaaatgaaca aaatagtcga agtacagaat gtaacaaaag tatacggaaa aaacaatgag
    10381 aaaaagacgc aagcattaag cggcatcagc ttcgatgtag aaaaaggcga atttattggg
    10441 atcatgggcg cttctggttc tggtaaatcg acacttttga atattttatc cacattagat
    10501 aaaccaacag atgggcatat ccgaatcaat caaaaagatg tgaccacatt aaaaggaaat
    10561 caactagcag attttcgtgc gaatgagatt ggctttattt tccaagactt taatttatta
    10621 gaaagcttga cagcacaaga aaatatcgct gttcctcttt ctttacaagg cgtcagacca
    10681 aaagaaatca agcaacgtgt ccaaaaaatt gcagaacgtt tatccatctc tcatattttg
    10741 gaaagctatc cttctgagat ttccggtgga caaaaacaac gggtcgccgc cgcacgtgca
    10801 ttgatcacac aaccaacgat tctattaggg gatgagccta caggtgcgct ggattccaaa
    10861 agtgcccggg atcttttaga tacgatggac gaattgaata caaaagatca tgtatcgatt
    10921 cttcttgtga cgcatgatcc gttttctgca agttattgcc aacgtatttt attcatcaag
    10981 gatggcggta tccatcaaga agtgaaacgt ggagatcaaa gccgtgattc cttctatcga
    11041 gaaatactat ctattcttgg aaacttggaa cagtaggggg agattgacta tgctttggaa
    11101 attatcactt actgggatca agagccgttt aagagactac ttggtgttat tctcaggatt
    11161 agttatggca tctgctattt tttacatgtt tgaatcaatg gcaagcaacg aagctttttt
    11221 gaaaagtaat acgatcgttg cggctacagt tatcattttc cgattcggtt ctgttttact
    11281 agggatcatc acattcgttt atattttata tgcaaattcc tttttgatga cgatgcggca
    11341 aaaagactat gcaatgttta tgatgctagg agcaaaaggc agaaaaatcg cacagatgat
    11401 tttttctgaa acattcttag tagggatcgc agctacttta gtgggttcag ctgtcggtgt
    11461 aggattgaca agtatcgtcc accgattatt agtggatcag ttagatctca atatttcgca
    11521 ttttacacct tttagtattc acgggttgtt gatcactgtt ttgttttttg ctgttttgtt
    11581 tttattagct gctgttgtca atgctttttc gattgtcaaa aaaccgattt tagcattgat
    11641 tcgtgcggat cagacaccaa caagaatcaa gcagcataaa ttcttgtttt tccttgaagt
    11701 agtactggga attgcttttc taggctgcgg ttactatatg atgaaacacg tggggaccta
    11761 tcaagtcttt ggtataggag tagccttagt tacgatcgta ttaggaactt atttcatttt
    11821 ccattctgtg atcattttct ttttatcatt actaaagaaa tcagaacaga tttcattgaa
    11881 aaaattgaac aatttcacat tgtcacagtt aaactttcgt attcgtgaat atacacaaat
    11941 gctctcaatg gtcgctatgc tgtttgcctt ggcactgggc gctttgacgg taggattagg
    12001 ttttaaaaat gaaattgcag acttgacaga aaacaattct ggatatgatc tagtgatgaa
    12061 taatcctcgg gcagaagatc agcaaaaaat caaagaactt tcaccaacac tttctgcttc
    12121 ttatactcaa aaagaagatg cgggaacgat ttactataat gcaagtgaat ttgcggctca
    12181 accattgatc atgataaaac atgaagatgg aacaccgccg aagatcacga aagaaaaagt
    12241 tcctgctgaa aaaatgaatg aactgactgt acaagaggaa cttcgaagct atgaattgcc
    12301 ggaacagcaa gaaaaagaaa tcaaggtagt cagtcaatca gaatttgatc aactgaactt
    12361 gccacaaacc actttacagc tagttcaggt aaaagacttc caagcaaacc tgaaaccaat
    12421 cgaaacactt gttgctcaaa ataaaatgaa caatccatct ttgcaaaaag tagagtacag
    12481 caaccagaaa tatgaaatgt atgaagtgta taatggtcta ttctctggtt ttgaatttat
    12541 gggattcttc ctaggtttag ctttcttgac catgcttgct agctgtttga tgttcaagat
    12601 cttgtcagga agcaagagtg acattgctcg ttatgaaatg cttgaaaaga taggaacacg
    12661 acgcgggttg cttaaacaat cgatccgtag agaagtaggc gtgttattct tagcaccagg
    12721 aatcttaggt gtagtccatg tcttattcgg attacaaatg tttggtctat tcatgcaaaa
    12781 tccatacaaa gatatttggg ttccgtttac gatcttcttc gtattgtatt tcatctacta
    12841 tgtactgacg acatggttat atactggaat cgtattgaaa aagagattgt gaaaaagctg
    12901 tcctgcatca agtaataaga acagccaagc aaaaatagct cctcatattt ttcgtttgat
    12961 tgggcttatt accgcagatg caagcttttg aacaccgttt gttcggaaaa agaggttgtg
    13021 acaatacttt tgtcacaacc ttttttcgcg gtcttttatt agaatatagt aaattttttc
    13081 tcgttactca cggaataagc tgttaagaaa acggtttcta tgtatactgg aatcagtgca
    13141 aatgaaagaa aagagggtgc aaggaacatg gaaatcaatg aacaaaattt tggcgaaaac
    13201 tatcacttga ttactatcac gaatcaaaat gggacatctt tgtctgtcag tgatcttggg
    13261 gcacgggttg ttcattttca aacaataatc gataatgaaa aacgagagtt gatcttaggt
    13321 tttgatgaag caaaagaata tctagaaaaa gacccttata tcggtgcttc aatcggacgt
    13381 atggctggac ggatcacgaa tggcacattc aaattagatg atgaaacgtt cgaagtaaaa
    13441 acagacccgg acactggtca ttgtttacat ggtggtgcac ctagctttga agccaagcag
    13501 tggcattata cagtcatcaa tggtgaaaac gaagcatcgg ttattttcta tcagactagc
    13561 ccagacatgg aaaacggatt tcctggaact ttagatgtag aagtacggta tacgctgacg
    13621 aacgatgata catggcgagt gacggtccaa gggatcagtg accgcaaaac agtattcaat
    13681 cctacaaatc atgtctattt caatttaacc ggtgatccag cacagtcaat cgacgaacat
    13741 atactttggt tgaatagccg attatttgct acgctcaata aagatacaac gcctacagga
    13801 gaagtagttt cagtaagtgg cacagcattt gacttccaac gtcctaaaaa attaggtgag
    13861 gtctttgcca gtgattttcg ccaatcaatg atagtgggcg gtatcgatca tccatttttg
    13921 ttgaaaaaac aatctggttt actaaatgct gcggaattga caagcctaga tgaaaaagta
    13981 tcgatccaag taaaaacaga tgcttcagga atcgtgattt ttacagcaaa ttttggagaa
    14041 gatggaccgg aaatgcgcgg gaataaatta gtaaatcatg gcggtatcac atttgagact
    14101 caagaactgc caggagcgga gcgacttgaa agttttggag atgtcactct ggaacctaat
    14161 caagtacgcg agtttgtaac ggaatacaaa ataaatataa agaaatagaa taaattaaaa
    14221 agggagtgtg acagtgtcac atcccctttt taatttattc tatttcttta aaggcagatc
    14281 aagccagaat gatttgtcta aacttaacaa ggttagtaca ggaacagttg cagctttaac
    14341 tgtacgagta gttgtttctg gtatctgtct tgccgtaaaa ttgttccaca aatcccagat
    14401 tgaagcgaca cggaagatgg aagaagcgtt gttgacgcgt tttatcgttg aaaattctaa
    14461 tcctgtgatt ggcacgccat ctgttgtcca tttgattggc acatcgaatc gcttagacat
    14521 attgaggatt tcggcgtttg cttcttcagt tgttgctgct tcttttttcg gttcatcata
    14581 ttttgtcagg tcgtacgctt cgatgatcgc gttcaatttt tgtgaatatt ggcgatctgt
    14641 agcataacgt ccttccaaat atttggttgc ttctttgtag tcttttgttt ccgacttcca
    14701 agttggtttg tagaaatcag gattgccagt cagtccattt ttgatcaagt cggcatagtc
    14761 ttccaaactt tccttgtaag aaggatattt acggaattgt gcgcggattt ggtagctttg
    14821 tccggaacta tcttgttcat gtgtattgaa ggtcacgctg cttccattat atgatccttt
    14881 gataccaaaa aggttatgat ttggttcgct tgataataag ctgtttccag atccactttc
    14941 aaggatagct tgagccatca tgactgatgc gtagattcct tctttttgcc cgatttcctg
    15001 tgcatcatct gcaatctttt tcaagaactg atcagttgtt tggttttgac tgaaatggaa
    15061 cgagccatct aatccatcta aaatagatga accagttagc gagcctgaag tagcaggtaa
    15121 acctgctaag tttactcgga cagcaaaatc aggcgtgaaa tctgaaatag aagttactcg
    15181 aactttatct cctggttggg gcgcatggat aaattgtccg ttcccaatat agatacctac
    15241 atggtgagta acaccggaag aaggtcccca gaagacgaga tcgccaggtt gggcctgact
    15301 tactggaatc tgcgtacctg catattgctg ttcgcctgtc cagccaccga tataatgacc
    15361 ggttgctttc atatatacgt aataagtcaa accagaacag tcaaaagtat ttggaccttt
    15421 ggctccccat acatatggtt ttccaagatg ctcgaatgct tctcgaacga ttgcttgttg
    15481 gacattcgtt gtatttgtag gcaatacagc atcaattggt gattttacaa caaaatcaga
    15541 agaagcagaa gatggattct ctataccgct ttgatttgct gtatttggac gagatgaagc
    15601 attgttcgtt ccgccattcg atgaaccatt gtttggatgg tttggttctc tctgagtatt
    15661 tccattgtta ttcgatccag atgggtttgt ttgattcgaa gaattcccgt tgttcgaatt
    15721 attgttatta ttgtttgaat tatttgaacc attattattg ttgttattgt tgttattacc
    15781 cacatctggt ttgtttggcg tttccggatc tggtgtacta gggacttctt cactaggatc
    15841 agttggtttc tctgttgaag tatccggtac aggttcaaat tctgcagtaa tagataaatt
    15901 gttcgtacct actgtaaagg tctttgcatc ataatttact tctttggcac cattaacagc
    15961 gactgaagca atttgttcac cttcagctgg cgtaatagtg taagttacct tcgtttccgc
    16021 taataaacct tctaccgttc cactttccgt aatatccaaa ggttgctgtt caggggaatc
    16081 cgctgtcgaa gcagtcagtt ggatcttacc aatcaaagaa ggagcaattg taagggaata
    16141 tgtctcggct ggcttttcat tttctgatgg atcagccgga tcaatttcag ttggctcggt
    16201 cgatcctgtt gttgagttag ttgttccagt tgggtcttct gtaaaagaat ccgttgtttc
    16261 actagtagct gagctggatg tagtcgtatc tgttgtgact gtttgatctg ctgtttgatt
    16321 atctacggca aatacggtat tggtcgacaa aacggacgga gcaatcagcc aagtagcagc
    16381 tagcaaacgt atcgtttttt tatttttcat aataaactag tccttttcct ttcattgatt
    16441 ttctgtctta ttcagcattc attagacatt ttttggaaca gataatcgtg tcgaaaagct
    16501 ttttcttttc ataaatctgt ctgtgtattc taaataaaac aatttgtaaa taagcaacga
    16561 gcattcattc gtttttcttt gacgttcatt ttattgcata gaccaccttt gtttggggat
    16621 aaacaagtgg ggataaaaat ggttatgcat atgtaaatta taccaaagtt tggaaagtat
    16681 cacaaaaatt tataaaaata atgatcctaa aaagaaaaag actgaaatat gtgataaaca
    16741 tctcatactt cagtcttttt cattaactat tcataagaca ttaggtcttc atcaaacccg
    16801 ctaacgagag tagtaatcat tgctacgact agactaacag ccagtcctgc taagtaccag
    16861 aaaaaagtac cggaaatgaa tgcaggcaat gtggtcagac taccaaatac aaaagcgatc
    16921 gctttcactt gggcaaatcc cattacagct ccaccagcag ctgcaccaat gcaagcagca
    16981 acaaatggtt ttttcaatgg gatcgcaatt ccgtaaacag ttggttcggt cactcccgca
    17041 agtaaaatcg aagcaaaagc agaaccggag atcgaacgag tttttgaacg tttacttcgt
    17101 agaaatacac ctaaagctgc accagccatt ccaaaattgg ctgctcctgt caacggaacg
    17161 attcggtcga acccataagc agagatatta ctgatcatga cagggtttac agcccattgg
    17221 ataccaaata ttaccaaaat attccaacca ccagcgatga ttgcgccgct gatcggtccg
    17281 ttaatatcca tcatccaagt aattgcggca gctaaacctt cgccaaggta aacacccgca
    17341 ggcccgaata ccattaacgt caaaggaacc gtgataacta atgaaagtaa aggtacaaat
    17401 actaattgca tattatcgcg aatatatttt ttgaggaatt tttcaacaaa agaataaaag
    17461 aaaataccta aaatcgccgg catgacagta gacgtatact gcatcagtac tacaggaatc
    17521 cccagaaaat cagtagctgc tttgccactg tctgaaagta aagaggtcag attcggttca
    17581 atcagtgctg cagcaatgac agccgcaata tatccattca ctttaaacgt tttggcggca
    17641 gaaaaagcaa gaaagattgg cagaaaataa aagacggcat tcgacgcagc agacaaaata
    17701 tgataagttc cgcttgtttc actaagccag ccaatcgtag tcgctaaaac aaccagacct
    17761 tttaatatac cagaaccggc aaacagcgga atgatcggcg taaagatttc cgatatcaaa
    17821 ccaaatagtt tttcgatcgg atttagcttt tctttcggag ctgaatgatc gatttgacgc
    17881 gtcaattcct tgtaagcagg agccaatccc tgatccatga ttatttctgc atatctatcg
    17941 agtaaaatga aatacttaat ggaagggatt tgctgtttta atttttctgc attggctact
    18001 ggctgttttt tcaatttgat acgaagccga gtcgcacatg gaaggacaga atcaatattg
    18061 tcttttcctc ccaactgttc aatcagcata tgaatctgct cgtacagtac catctgttca
    18121 ggattcattg tcgtttccat tagaagacca ctccactcac taatataata ttggcgtaag
    18181 gtgtcatttc gcctgtacga ataaatgcat gacagttatt caactctttt ttcatttctt
    18241 catgtgggat aaagctaatc ggtgtatctg gtaacaataa tttgattttt tccaatattt
    18301 ccggattcat tgtctttatt tcttccgcca attcaatcga ttgtacctca agttcttcta
    18361 aaacgttttc taaaacagat aaaaagcttg gaagaccgtt tgagacagcc aaatctattt
    18421 tttcagtacc aaaggggaca ggcatgcctg catccccgat acttaattta tcaaagtgcc
    18481 ccatttgtgc gattactcgt gaaatatctg aattgattac ttttcctttt ttcatgtttg
    18541 tttcttcctc tcattgttaa ttttagactg ctgattgttc taaagcttcg cggtaaggga
    18601 tagaaggttg cgcaccataa gactgcacag caacagaaga ggctagattt ccataaagga
    18661 tcgcttcttt caagttacta aggtctggct gaagtgtgct gcttaatgcg ccaataaatg
    18721 tatcacctgc ggctgttgtg tcaacggcat ccactttaaa agcagggacg ataccgtgtt
    18781 ctttttctgt atgatagaaa gcgccggcac tgcctagtgt aatgattact gttccaatac
    18841 ctaattcatg gagtttttcg gctgctgcga ccaaactgtt atgatctgtc actctgattc
    18901 ctgtaatgat ttctgtttct gtttcatttg gtataatgat atctgtcttt tcaagtagtt
    18961 cagtaggaat cgtttcacga gctggtgcag gattcaggat cgttgttttt cctgcgtctt
    19021 ttgcaataga aaaagctagg atcgtcgcat ctaagctact ttcaaactga gcaataataa
    19081 agtcactgtt tgtaatcagt tgcttgtttt ttaggacttc ttgttcatgg aaagcattat
    19141 ttgcccctgc atggatcaag atactatttt ctcctgctgc gtctaccata atcattgctt
    19201 gtccggttgt ggcgccttgg atttcagcta tcccagatgt atcgatgttt tcttttgtca
    19261 gtagatctaa taactgttgt ccttcgctgt cagccccaac gcctccaata aaagatgtcc
    19321 gtgcgcctga acgtttggct gccactgctt ggttggcgcc tttacctccg ccagcgtgaa
    19381 aaatctcatg cgcatgcatc gtttcgcctg gcttgggcat gttggttaaa cgaagggtag
    19441 tgtccatatt aatacttcca attactgtaa ccgtgttcat tttacaaacc tccaactatc
    19501 tcatttattt tgatgggaaa aattattttt taaaacgttt tagtaaaacg ttttaatagt
    19561 tcgataaaaa tatagcacac cttgaaagct atttcaaggg tgcagttgaa aatctttttt
    19621 ctaatcgtac aggtaatctt ttttcttccc attctttttc tgggaattgg atccgatcta
    19681 acaataattt ggcagatgtt tgtcccaatt cgaagatcgg ttgtgcgatc gttgtcagtt
    19741 tcggcttgat atactcgcac atatctatat tatcatagcc aataatgctg tagtcttcag
    19801 ggatgctttt tccagattcc tctaatccgc gatataatcc aaaagctaat tcatcattta
    19861 aagcaaacac accagttgca gcagaatcaa gaagttctgc tgtgatttgg tagccacctt
    19921 gttttgagaa ctgtgtaggt aagaggatca gttggtcgtg agagatttgg taaacatcaa
    19981 gagcagattt aaacccctca atccgagcgt ggacattttc cggcggattt tcaggataga
    20041 caagggcgat cgtttgatga cctagactaa gcaagtgcat gcccgctagg taaccaccgc
    20101 gaaaatcgtc tgttcgtacg gcatcactaa atccttcaga ttttttctga tccaaaacaa
    20161 tgaagggccg gccttgtttt ttcaaatttt cgttgattgc atctgtagag acagcagaag
    20221 tcgcgataat gaatccatcc acacctcgac gtgtgagctc ggctagatat tcgatttctt
    20281 tttgatgatc agaatcagca ttacataata tcgtgacgaa attctgctta tacaagatat
    20341 cctcaattcc tcgcatcagt gtactgaaga atggattcgt gatatcagga acgagtacac
    20401 caattgtttt cgtttccttg gtaatcattt gtctagcaaa atagtcaggc tgatagccta
    20461 attcttcttt ggcagctaaa actttctgaa cagttttcgg actgaatttc tccgtatttc
    20521 catttaatat caaggagaca gttgtgattg aaacgccgga aagtttagcg acttctttga
    20581 ttgtgatctt ttttttcacc atgttcatac tcctatctaa atcctgtggt tattttccca
    20641 tgaaatcaaa aagaagtaaa tgaaaatcac gtgtgccagt acttatttgc tttgttggat
    20701 agcttcgatt atttgtttcg ttgagcgtac tcgtgcagtt ttcggaaata tcttttttat
    20761 gaacaattga tgggattctt tgtcacgatc actgcaagca tcttcagcaa gtacgacatg
    20821 atacccatgt tggaaggcat ctaatgcagt agcatataca ccgtttgttg tcgctacacc
    20881 gcttaaaatg atagtttcga ttccacgccg gcgaagttga agatcaagag aagtaccaaa
    20941 aaaggcactt ggattgtatt ttgtgatagt caacatattg tttgtatctt tcaaggaatc
    21001 cttcaacaac aagtcagtga attctggagg tacagaagca gtcattccac ccatatcagt
    21061 ttgttgactc aaataaggga aagtggagat gtctacgttc actaaaactt tcaaggcagc
    21121 ggtacgtttc aatgttctta ctaacaaatc attgtttgac agaatagatt gtgcagtgtg
    21181 tggagagagt gtaccgttat ttacgatccc tttttgcatg tcgatcgcga caaaagcagt
    21241 ttttgataaa tcaaaaatca tattttcctt taaatcattc atgatgttcc ttctttcaaa
    21301 taacaatgtt ttttatgtaa gtaaatcata aatcgtttat ttgtcaacta aataaaggat
    21361 tcctttcttt agtctagaga aattcagtgg taaaataaat aagtgtgaga aaacgcattc
    21421 tatgcataga tatagcgaga aatatcgtga aaatggagga atcagagtga agtatgtcga
    21481 agtaaaaaat gaatacaaac gatacaaaat gggagaaacg accattacag caaatgacga
    21541 tatttctttt tcaattgaaa aaggcgaatt agtgattata cttggtccaa gtggagcagg
    21601 aaagtcaacg attcttaata ttttaggtgg gatggataca cctgatgaag gtcagatcat
    21661 tattgatgac acagatattg cgcaattttc agataaacag cttactgctt accgacgaac
    21721 agatgtaggg ttcgttttcc aattctacaa tctcgttcct aatctaacag caaaagaaaa
    21781 tgtggaattg gcaacggaag tttctcctga tgcgcttgat cctgtagagg tattgaggca
    21841 agtgggccta gctcatcgat tgaataactt tccgtcccaa ttatcaggag gcgaacagca
    21901 gagggtttca attgctcgtg cactagctaa aaatcccaaa cttcttttat gtgatgaacc
    21961 gacaggcgcg ctggattttg aaacgggcaa gcaagtattg aaattattgc aaaacgctag
    22021 cagacaacac ggcaataccg ttttgatcat tacacataat tctgctttag cgcccatcgc
    22081 tgatagagtc attcacatta atgatgctaa agtaaggtct gttgaattaa atgatcatcc
    22141 ttcatccatt gatgagattg tatggtaggg ggattttatg aaaacaagaa catatcttaa
    22201 agcaggtttt cgcgaaattc ggcaatctaa aggacgattc attgcaatca tccttattgt
    22261 catgctagga acacttttat ttgtaggtgt caaaactgct ggacctgtca tgcaaaaaac
    22321 gatggatcac tatgttggta cagcaggact ttctgatttg caaatcgttt ctactggtgg
    22381 cttgacacaa aaagatattg ctcaagcaga aaagatccca gatgcaaaag tagaaacagg
    22441 aaaacagatc tattattcca atactggcaa aaacgaagtg attcaaatat tttcttataa
    22501 caaaaataac aagcagaaca agctacaatt aactgatgga aaactcccgg aaaaaccaaa
    22561 ccagcttgta ttggatgaaa aagcggaaga tgaagggtat aaaatcggtg atatttatca
    22621 gattgattca gatgaattga aagaaaaaga gtataccatc acgggctttg tccgttctcc
    22681 attgttcatc aacaatttgg agagaggata cgcgaacgtc ggaaatggta gcgtcgatta
    22741 ttttgtctat ttacctgaat ccgtttttaa aacagatatt tattctgtct tatatcttga
    22801 ttttacaaac gcaaagaatt tgaatacgta cagcaaagct tacaaagata aaatggagca
    22861 aaatcaagaa aaggcagaaa agtatttaca agatcgaccc gaagaacgct tagaagagct
    22921 gaaaaaatcg gccaacgaag aattagaacc ggcacagcaa aaaatagcgg atggcaaagc
    22981 acaaacaacg caagcaagaa cacggttaga agatgctaaa aaacagttag cgcaacagtc
    23041 agcaactatc cagcagcttc ctgaagcgca acgaacaatc gctgttcaaa cattatctca
    23101 acaagaagct caacttgctg aacaagaaag gcaattagtt gagaaagaac gtgaactggc
    23161 ctctgcagag gaagaattga atcgaaatgc agaaaaaatt gaaaatttaa ctaaaccatc
    23221 atacctatac aatgaacgtt cagaaaatgt cggttttcaa gaatttggtg atctgtctga
    23281 tcgtatcgct gcgattgcca atgtttttcc tgttttcttt ttctttattg ctgcattgat
    23341 cacctttacg acaatgacac gtatggtaga agaaaaccgc agggaaatcg ggacattaaa
    23401 ggcgttaggt tatacgaaag ttgaaatcgc aaaaaaatat gcaatctatg caagtctagc
    23461 ctcagggata ggcattgttt taggaacgat attaggaacg aatcttttgc caaggatcat
    23521 ttttgagctg tctaacgagc ggtatgatat tgggagtgcg cttatttttt atgactggcc
    23581 gccgatttta caagcagctg ccgcattctt cattgccgca tttggcgctg caatgatcgt
    23641 tttattcaaa gatttaagag aacggcctgc tgcattgctt caaccgaaag caccgaagcc
    23701 agggaaacgc atttttcttg aatacatcac tccgctgtgg tcacgcctta gctttaatca
    23761 aaaaatcagt taccgaaatc tcttccgata taagtcaaga atgcttatgg cgattatcgg
    23821 aattgctgga tgtgccgggc tgatggttgc aggcgtggga ttgaaagatt ctctaagttc
    23881 tgtctcagcc aaacaatttg gaccgatcat tgactatcaa gcaatcgtta cattggattc
    23941 atccacggaa gatagtcgtc aaaaagcagc ggatatgctg cagaagcaag aaaaagtaaa
    24001 tgagatccta gctattcata ctcaaaccgt agaattgaga aaaaaaggac atgcttcgca
    24061 aagtctgaca gtgatcgtac caagtaaaac agctgatttg gatcgtttta tccatttaac
    24121 tgatcttgaa gagaacccac gctccttgcc taaaacagga atcgctatta cgcaaaaagc
    24181 agcagaacta tttgacttat ctacaggaga tcatatttcg ctttatgatg aagatcaaaa
    24241 agaatggaaa gtcgaagtaa aagaaatcgt gaaaaactat ctaggtagct ttatttatat
    24301 gtcccctgaa tattatgctt cagttactga tcaatcgatg atggataatg catttttgct
    24361 gcgtacagat aagatgacaa caaaagaaga agaaatgctt tccgagaaac tgcttgccac
    24421 agacgctgtg acaaatacgt ctttcatgtc caaacaaatc gaaacgcaag aagaatcaat
    24481 ggcgaactta gactcggttg tcttaatctt tgtcgtatta tcaggactgc tggcttttat
    24541 cgtcttgtat aatctaacta atatcaatat ttccgagcgt gtacgcgaat tatctacaat
    24601 aaaagtcctt ggattttttg ataaagaagt cacgatgtac attgttcgag aaaatatcat
    24661 ctttactctt ttaggaatca tcggaggatt tggtgtagga tatatattga ctgacttcat
    24721 cttgcaacaa gcgtctatgg agaatgtcat ctttccatta gtgatcacat ggtgggctta
    24781 tgtcttatca gcaggattaa ctatcgtatt cacggttatt gtgatgatcg ttacccattt
    24841 caaattaaag catatcgata tgattgatgc gttgaaatcg aatgaataaa aacagaggtt
    24901 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag cttctcatat
    24961 ttttcgtttg attgggcgta ttaccgcaga tgcaagcttt taaacaccgc ttaaggaaga
    25021 ggttgtgaaa tcagcgtttt gagctaataa cgagggtcag ctgctaattg aacaccgtga
    25081 atcagaggtt gtgaaaaagc tgtcctgcat cgagcaaaaa gaatactcaa ataaaattag
    25141 ctcctcatgt tttacatttg agaagactga ttgccgtaga taaaagcttt tgagcaccat
    25201 ttatagaaga aacaagaata ttttgctatt ttaaacaaga ggatagacaa atacatgtct
    25261 gatctcttgt tttttattgg gcaacagacc tcttagaatg tataaagata aattttacaa
    25321 acgctttcgg ttcagttata ataataaatg ataacttgta tatataagtt ttggtaggta
    25381 ataaatcagt tgaatggagg taaatatcca tgacatttaa agacaaagtc atttaccaaa
    25441 tctatcccaa atcttacaaa gacagtaatg gtgatggaat tggagattta aaaggaatca
    25501 aagaaaaact cccgtatctg aatgatctag gcatcgacat gatttggcta aaccctattt
    25561 atccaagccc tcaaaaagac aacggttatg atatctctga ttacacagcc atcgatccta
    25621 tctttggtac gatggaggaa ttcgaacagc taatagccga agcaaagaaa taccggatag
    25681 aaatcatgct cgatatggtg ctgaatcacg tttcgacaga acatgaatgg ttcaaaaaag
    25741 cactagcagg ggaccagcat tatcaggact tcttcatttt aagagaagag ccaacggatt
    25801 gggtatcaaa atttggtgga agtgcttggt cgccatttgg agatacgggg aaatattatt
    25861 tgcacttata tgatcggaca caagctgact tgaactggcg gaaccaagca gtaagagagg
    25921 aactattcaa agttgttcgt ttttggatgg aaaaaggggt aaaaggattc cgtttcgatg
    25981 ttatcaatgt tatcggtaaa gacgaacaat tgaaaaataa taaagaaaat gatggcaaac
    26041 ctgaatatac ggacaaacca atcacccata cgtatctaaa agaattgaac caagcaacgt
    26101 ttgggacgga ttccactatc atcacagtcg gtgaaatgag ctctacgacg atcgaaaatt
    26161 gtatcttgta tacagaacct agtagagaag aattatcaat ggtctttaat ttccatcatt
    26221 tgaaagtcga ttatgaaaat gggaataaat ggtctactcc tccatttgat tttgcagaat
    26281 taaagcgact atttcataca tggggagaaa agatgagtga gggtaacggc tggaatgctc
    26341 tattttttaa taatcatgat cagccacgtg cgctcaatcg atttgtagct atcgatcagt
    26401 atcgaaaaca aggagcagag atgctagcaa ccatgatcca tttgaaccgt gggacgccct
    26461 atatttatat gggagaagaa atcggcatga tcgacccaga ctattcatcg atttccgact
    26521 atattgacgt agaaagtttg aatgcttata agttactcct tgaacaagga ttcacagaaa
    26581 aagaagcgtt tcgtcggatc aaagcaaaat ctcgcgataa ctctcgaaca cccatgcaat
    26641 ggtcagacac agaacaagca ggatttacta cagggaaacc ttggttaaaa gttggaggca
    26701 agctagaaga gattaatgta gaaaaagaac tatcttctga agattctatt ttgtcctatt
    26761 acaagaaatt gattcggctg agaaaaacat atccaatcgt tgcacaagga gattatcatg
    26821 cttatgaagc aaatcatccg gaagtttatg gctttcttcg ccaatttgaa ggacagcagc
    26881 tgcttgtatt aacaaatttc tatgataaag atacaaggat cgccatccca gaaggattca
    26941 cagaagccaa tattcttatc gataattatt ccgatactgt tcttcatcaa agtctggagc
    27001 taaaaccata ccaggcaatt gctttgctga aaaattaaaa caaaaacaca aaacgtcgtt
    27061 cctacgagct attctcgtaa gatcgacgtt ttgtgtttta tttaaaataa tcttcttcag
    27121 aaaatgaaga gttttgatac tctcctttat cgccataaaa tttattgtag cgttgtttga
    27181 atttacggaa aataaaagta acgagtaatt tgactaacgt atagatagga ataccaaaaa
    27241 taacgcccac aattcccatt agatcaccca tgacaagtaa aacgattaag atcgtaatcg
    27301 gatggatctg taaacgatca cccattactc gaggaatcac caagtcaccg tggagaagtt
    27361 gtacggcaaa ccagacaatg acaaatttga cagccataaa agtagagtct tggaatgcaa
    27421 tgatcaaacc tggaaagaag gcgataaacg gcccaatata tggaatgata cataacaacc
    27481 cagcagaaat agctaaaaca ctagcaaatt ctaatccgat cagtaagaaa caaacccagt
    27541 agactgctcc aaggataaat gaagcaatga tttgcccctt tagaaatgaa cccaattgtt
    27601 gattagcaat ctttgtcaaa tttttaaaat ctgtacgaaa tgctggtggg acaatcgcta
    27661 aaactgactg ataaaatttt tgaggatctc tcaaaaggaa aaaagcgaca attggaccag
    27721 taaataaagt aataaaaata gctgtaacag ttgaaaaaat gttgctgatc cgttgtgcgc
    27781 cactttccca ataatttcca ataaatccag ctatatcaga cgtcacgtcg tcaatagaag
    27841 cgaaaaattg attaaatgaa tcggcaaaag gtgttttctc caaaaattgt cggagactct
    27901 cttgaaaatc ttgaaacaaa tctggcaaac tactgatcaa tgtctttgcc tgttcttcaa
    27961 gaaaaggaac aagccatacg cttccaagcc ccaataaaaa taaaataatc acataaacga
    28021 taatgactga caagttcctc gaaaggtgct tgctcaaacg tttgatgact ggttccaaaa
    28081 gataatacaa gatcagtgca aacaataatg ggggcaagat agtagcgata atgattccga
    28141 caggcttgaa tataaacgag atctgatgga aaaaataaat gatcagcgca agtaagataa
    28201 ctattcctaa aacatagtaa gaggtttttc ctcctaaaaa gcggatcaaa cgattcgttg
    28261 tatctgtttc ttttttcaat ctttttcctc ctttatctat aacttcatta tagacaaaag
    28321 cgggtataaa aggaaaatga tagaggttga ttgcaaaaat atcgtcaatc attcacataa
    28381 actttctcat caattaaaat aagaaaacgc ttgacagtta ttttaaccat atgataaatt
    28441 aaatcctgtt gctaaaacgt aactattacg gtttacaaaa ggcgaatcgg aacattcaaa
    28501 tgaaagaaga tgagaagagg agtgtcataa atgaaacgat tgataggtat attggccatg
    28561 ctggttttag caggtatgtt aactgcttgc ggggcaagtg ggaaagccga ggacagtaaa
    28621 gaaaaattga gcgtgatgac gaccttttat cccatgtatg attttacaaa agcaatcgtc
    28681 ggggatgaag gagaagtaga gttattgatt ccagcaggga ctgattccca cgattatgaa
    28741 ccttctgcta aagacatggc aaagatccaa gatacagata tctttgttta taatgatgaa
    28801 aacatggaaa catgggtccc cgcaatccaa aaaacattac aagaaggcaa tgtccatacg
    28861 ataaaagcga cagaaggtat gcttttactt ccgggaagtg aagaaggaca tgatcatgac
    28921 catgaacacg gggaagaagg ccatacacac gagctagacc cacatgtatg gctagcacca
    28981 agtttagcaa tcaagcaggt agcaagcata cgtgatcagc tgattgaagc ttacccagaa
    29041 aaacaggaag tatggacaaa aaatgcagca gcctataccg agaaacttca agcactccat
    29101 cagctttatc aagaaacctt taagcaagca aaacaaagat cttttatcac gcaacatgct
    29161 gcattcaact atctggcatt agaatatgga ttgaatcaag tatcgattgc tggtctttct
    29221 tctagtgaag aaccgtctgc ggcgagaatc gctgaactga aacactttgt taaagaacat
    29281 ggaatcaact atatttattt tgaagaaaac gccaaagata gtattgccag aacgttagca
    29341 aatgaagcag gtgtatcttt agaagtattg aatcctttgg aaggattgac gaatgaacaa
    29401 atagaaaatg gagaaaacta tctttctatc atggaagcaa acctcgaagc gttgaaaaaa
    29461 acgacagaga cagaaaaccc gttagaagat actttgaccc ccaaaaaaga aaagagcgtc
    29521 tataacggtt atttcgaaga cgaggatgta caagatcgct ctctttcaga ttgggcagga
    29581 acttggcaaa cagtagatac gtatatagaa gatgggacat ttgatcctgt ttttgaatat
    29641 aaagaaaaat tgaatcagga taagacagca caagaatata aagaatatta tacgaagggc
    29701 tatcaaacag atattgcttc aatcaagatc agtgagaaag agatggcatt tacgtttaag
    29761 gatggaacaa cgaaacgttc aaattatcgt tatgtaggga aagaaatctt gacctacgag
    29821 gcaggaaacc gtggcgtaag gtatctattc gaagcagaag ataaggaaag tggcgctttt
    29881 agatatattc aattcagtga tcacacgatt gcaccggctg actccgaaca ttttcattta
    29941 tatgcaggaa atgaaagtca agaagcattg ctgaaagaaa tggagaattg gccaacattt
    30001 tatccagata caatggatgg acgtgaaatt gcacaggaaa tgcttttgca ctgataggca
    30061 aaaaagaacc gaagggtttg gatcggctgg tcatttagtc ggtccaaact attcggttct
    30121 ttttatgaaa tcaatttctt taatccacgg atagaggctg ggatggtctc gccgtttgcc
    30181 aacgtgactt ctctggtttt tttattaatc gaccgcacat tttgtgtatt gataacatag
    30241 gatttatgac aacggataaa attccgatgc attttctcga tttctttgat cttctcatag
    30301 aattgtaatt gggcatgagt caaatggact tccagtttat gtggtgctcc tagcgaagta
    30361 gaaaaatatt ggatgtcttt gatcggtaaa aatttgatct catcattaaa ctctattttg
    30421 aagatatctt tttggatctg ggacatttga aaatcttcga aaattttgct caggatatgc
    30481 tcgacatttt cttttaaatc ataaagatcc tctttgacga tataatcagt cggttcaatg
    30541 ttgcttttta agattttcat cgacatttcc gtatgggaag tcacatagat tatttttcct
    30601 aaaggatcta attcacggat caatttaccg atcgctacac catccatttc actgtcttct
    30661 agttcgatat ctaaaaagta aataccaaaa gaagaagttc tgatcttggc tgcattgaga
    30721 agttcttccg gatcagaggt agaaatatgg acataactgt ctaagttttc aatcatgatt
    30781 ctatttttga tcaccgttga taaaacttct aattgttttg gatcgtcttc acaaatataa
    30841 atgggaatca tatcattact cctttatttt atttgtatat aaatcgtttg agaaaaacgc
    30901 tggttttcaa ttgatgtttc aaggaaaaga taaggattgg tctttgtcaa ttcatccaag
    30961 ataaacaagc caaggccttc gttttttgga tttgtttttg ttgagaaccc tttttgtttc
    31021 aactggttta acggcaatgt atttgttgtt gtattgatca cacgaatcat tacggaatga
    31081 ttcttcttga gtatggtcaa ttcgattttt ttcttctttg cagcactagc tccttcaatc
    31141 gcattgtcca agataatacc aagcatacgt acaaggttta ccgtatgttt cgtatccagt
    31201 tcgattggct caggaaaatg aagctggacg accaaccctt tttcctgtgc catcatgagt
    31261 tttaatgaca gtaaactacg gatctcagga actttcatat tatccaacat acttagattg
    31321 gccggaaaaa ggttcatcat ctggcgtgta ggtaatatcg tttgatcata ataagaccgt
    31381 aatccttcta agtcgccttc tgaaatatag ctgtgaagag aaaaaagcag attttggtaa
    31441 tcatgtttga attctctcaa gtcttgatag tttttttcta gatctttgat ataatcctgt
    31501 tgcatcctga cttgttgctc taataactga tcagctaatt tcttattaga gattttccaa
    31561 taataaacca agatgatcag gccaacacac agatatagaa tgaaaaaact cgtattcaaa
    31621 gctaagacat caggtgtttc accagaaaaa cgggtataaa aaataatgat atagtatgta
    31681 aataatatca atgtcccgat cgtaccgatc atacggcggt ccacagtgtg aaaccaagtc
    31741 tctaacgttt ttttaaaaca aaaagctaat aaagcagata aaaaagcgga taaggcaatg
    31801 tgaaaatact gcaatgaatc tcctggttca ataaccgaag atttcaaaac aaaaaaatcg
    31861 ccgatgcttg ttaagtgatc tcctaaaagc gacgtcaata acccaaaagg aagggcgtaa
    31921 accaattgtt gacgcgaagt cgaaaagaag aaaaaagtaa gcatcagcat tcctatagca
    31981 attagagcag taaaaatccc taaaatcgaa tagacccatc caatcaaaat acaagaaatc
    32041 agaatgactc ccgcaaacag atatttgtat cggatgtgat ggtcaatcaa taagatacaa
    32101 attgtgtaaa tcaaatattg caacgctatg gaccataaaa acataaagta cagctcccat
    32161 tgatttttac caaattatag cacaattagc gtattatttt tttaattttt cagggatttt
    32221 gaattcagaa ctcataccaa agcagcagcc agatacaaaa aagtcagata agttagttaa
    32281 ttgtttaatg attgtttttt tcatgaaaga ttcctccaaa attcatcaag tagtttgtaa
    32341 taggaagcaa cgtagctatt tctaaaacaa tcccaagtag caaataggta gaaaagtaag
    32401 aagctgagaa aaataaagta atgagagaaa aaattagaaa catgctgatc gccttcttta
    32461 ataatggggg acgtttctcg ggttcaatgg gattgattgc tgtacctctt gatccatagc
    32521 gaagcagtaa caaaaagcag ctgattaaca aaaagaccat cattgggaag gagatagtca
    32581 attgcagatg tttcatcacc aagggaacgc cccataaata aagtagtgtc cacagcagac
    32641 aaacgaattc agagtcggaa tgcaatccat aagcatatct gcggatgcag atataagaaa
    32701 gaaaggtgat tcctgtttcc gcccatgagc ctgtcaccag agaaaagact agaacgaccg
    32761 ctagttttcc aagattattc aataaaactt ctaaggcaaa ttttacttgg acatacacca
    32821 tatcttcttc cgatttgtct ccgctgaata aggcttctaa taatttgttc acaactttat
    32881 ctttcatctc atacgtacct ccaccacaaa ttttatgcta aaaaaaataa aaaacgtctt
    32941 ttgtttcata aaaagtggtt ttgacatcaa aaccgtcatg atttcctaaa aaaatcttcg
    33001 ttttccaaga accttaccaa aaaaagtgac agttttgata cgaaaagtac tttttatgac
    33061 aagtttgtgc tttttcgagt gatttatgtt aaaaaattac tgaccttata aaaggtgatg
    33121 gagggattct tatggaaaat gaacaattgt ttgaagtcgg cgaaacatat gcatttaaat
    33181 ctgatttatt tgaatcacca ataaaaggaa aaatagaaaa aatctatgaa aatagtgtga
    33241 tgatacgtgt catgaaatgc gcagtagaag acaatgatac cgctcataat ctgcactggc
    33301 agttagttgt acgcaaatca agtacaatag aagaataaaa acagataaaa tgttgagagc
    33361 ataaagaggt tgtgagtctc ccgtttagct ctgagttaca aggaataatg ttaaaaaaca
    33421 gcttttcatg ttttatgaat attgccttgt gaccgaggtg ttggcaggag aatactgttt
    33481 atttgaaaaa agggctgcga caagactttt gtcacagcct ttattttcat gaataggagt
    33541 tacttttggc tacttttaga gaagtagcat ttaaggagca gataaagtca aggcttttat
    33601 ttctataaat gaagtagtaa aatgaagaac agattttatt acaggaagga tgccgataat
    33661 tgtgatcatt gttgcaggaa cgatcggtgc agggaaaagc acactgactg aaatgcttgc
    33721 ccaagattta gaaacaaaac ctttttatga gaacgtggaa gataatgaag tattgccgct
    33781 attttattct aatccagaaa agtatacttt tttattacag attttctttt tgaacaaacg
    33841 ctttttggca atcaaagatg ctttcagcca tgatgacaac gtactagacc gctccatcta
    33901 cgaagatagt atgctgtttc atttgaatgc agatttaggg cgtgtttctg aagtagaagt
    33961 aaagcagtat gaaggtcttt tagaaacgat gctgaaggag ttagaagaaa tttcgccaca
    34021 aaagaaacca gatctactgg tttatattcg tgtatccttt gaaactatgt tagcgagaat
    34081 caaaaaaaga ggccgggaat atgaacagct agaacaagat cctgaactct attcctacta
    34141 taaagaactc aatcgacgat acgaagagtg gtatgaacag tttgatatat gtcccaaaat
    34201 agtgatcgat ggggacaaat atgatttcgt agccgatccg gcatgtggag aacaaatcgt
    34261 acaagaaatc aagatgcggg caaagaaaat gacagaagag gcagatgccc agtcgatccg
    34321 ctacactaca aataacccga aagcaaaggg aatctttaca actaaataat ataaaaacta
    34381 agcaaattgc tcactcgcag atatttctct gtgagcagca tcttgcttag tttttttgat
    34441 tcattgagat caaatagtga accgattcgt atgataaaat tgccataaat gaaatgtctg
    34501 agtgagggcc atgatcaaaa ataaaatgga aacgatcaaa atcgaatggg cgccaaacag
    34561 atgatgacag aaaacaagga caatagctcc tgcgataaag gcaagaacga cacttagata
    34621 gtggaaaaat cgatcaaaat ctgctttttc tttagaaata caataatcat ataagttcgt
    34681 tgctacccct tttaaatttc cagttgtaaa taaattagtg taggcacgcc cgttgatttt
    34741 atcaaaagct acccactgga tcgatgcagt aaaagcaatc aaaatcgtta ctaatgcggg
    34801 atgctcatgg acgggtgtca aactaacaaa gaaaaaaatc actgcttcat aatatagaac
    34861 aaacaagcgc cagaaatgtt tttctttttt tctaaaataa tcaatcagat actttgttag
    34921 aagaatccct aagaaaaaga aaagggtaga caatactttt ttaccaacac ttagccattc
    34981 tccgtcaaat gcttggatga tcgatagaat gatattgcca gtttgagcag aggcaaaagc
    35041 accatattgg atataagtat aactgtccat ggctcctccg ataaatgtca gcaaaagtcc
    35101 tattgtacgc ccctcgtgaa aggaagtctg catttttttc atcacctttt atgaatattt
    35161 ttgtcttcct tatcttagca taaacgattg aaaaaaagga aaaattttca gaaaactaaa
    35221 atcatatcgc ttcccatttt catttttaga aaggtctgtt agtataaaga aaaaatagac
    35281 aacaaaactt taaataacca actttaaata accaacttta aataaccaac ttgaaataaa
    35341 caaattcaaa gaagaaagat gggaaggaaa tcaatcagtt gaatgaaaaa gaaattctcc
    35401 gattacaaaa agaattgaaa cgctgggaga acaagtataa aaagcttcaa caagtctttc
    35461 ggctacaaga agaaatcatt gctacctatg aagcggctta tggcgaagca cccggactta
    35521 ttgaggaaga agtacaagta aaagaaagtg aaggaaacag ctctttcttt aaaatgatgg
    35581 agaaacgttc ctataatcgc ttcaatcaag aacaaaaagc agctatcaca tatgatatga
    35641 agaaacatct tcgaatcata gcaggagctg ggagcggcaa aacgcaaaca atctgtgcaa
    35701 aagctgttta tctgatgacg caaaaacaag tagacgaaga acgcatacta atgatcactt
    35761 ttacaaggaa cgctgcaaat gaactaaaaa aacgagtaga taatttcagc cagagaaaaa
    35821 ccgctgtcca tatcggaaca ttccatagta tcttttttag gatatacaat gaaatttgtc
    35881 gaaaatttcc tgaagtagca atgcaaggaa tacaaggaga cttttcaaag gatactgcac
    35941 aaaaagtgaa tgctgttttg caacagctga tacgtaaata taatctttat atatttgatc
    36001 aatatggaga aaaaacgatt gcttctcggt tagactattg gcagaatatg aacctttcag
    36061 tagaagaaat ggttcagtta gttaaagaaa aatatgattc cattgataag aatgcacgac
    36121 agccgatatc agaacgactg tatggattgc tcacggaact ccaagaacaa aaaagaagcc
    36181 agcaattgct agagttcaat gatgtactcc aaaatctgaa aagcgctttg gagaatgagg
    36241 agatccagca ttatatcggc caaaaatatg attatctatt cattgatgaa tttcaagata
    36301 ctaatccact tcaatgggaa atcgtgaaac ggatgacaaa ggaaaacagg atcaagttga
    36361 ttgttgttgg agatgatgat cagagtatct atggattcag aggatcagag ccagcataca
    36421 tcaagaactt tgaaaaagaa tatcctacca aaactctttt cttattaact aattatcgtt
    36481 ctcgggcagc tattgtccaa ggagcaaata gattgatcag ctataataaa aatgatcgga
    36541 taccaaaggc gatgattcca gcacaaaaag aagcaggtgt tatggaagcc tatttgtttt
    36601 ctgatactaa agcagaaagt cagtggctaa tcaaacaaat tcagacattt attcaaaaaa
    36661 atgggaaata taaggaatca atcatattat accgatcagc ttcacaaacg cagcagcttg
    36721 tccaatctct gctgaaaacg aatattcctt ttgtactgga agcagatagt ccatatgaag
    36781 gtatctttgg tatcaagtct ttccaacatt tctatcaaaa aattgttcat tggcaaacag
    36841 cactgaatct gcaaaagaaa aatcaggcct accagcaatt gctccggcag ctgatggcag
    36901 actgctacct gaaaaaaagt gaatgcgatc aatacttttc tcctaaatat caaaatatag
    36961 ccgttgcaga ttatattttg tcgataagcc ccaatttaaa atcgaaatct gcagaaatcc
    37021 gagagtttga ggaagcgttg cgtaaaacag accagcatca agaaatctat tcgcttgttc
    37081 aaagctatct tcatctgcca cgtatagcta aggaaatcga ccagagtgat caagaatgga
    37141 tacgagaaga agtaaagcag catgctactt tcagaagact ccaagcctta tcgcaagaaa
    37201 cccaagcgac agctaaagaa ttaaaaaccc gcttgattgc ttacagacaa ggaaaacttg
    37261 atgcactatg tatccagagc attcacaaaa gtaaaggtct tagttaccga aatgtctttt
    37321 tgattggttg taacgaagga agtttgcctt ataacggagc gacagaaaag aaagtaatcg
    37381 actttaatga aataaaagca gaaccagtga cgacgataga agaagaacga agactatttt
    37441 atgttgcgat gactagagca agaaatcgtc tgtatctatg tgtacctcaa atgaaaaatt
    37501 caagaaaatt gaaagtatcg agatttatca aagaaaccgg gagtcgtgtg aaaaaaggaa
    37561 agtgatagaa gagagggtgt gacagaagtg gtcagtttca agaaagaaga aggaatgtac
    37621 gaaaattgct tctcaaattt ttgtgaaact tcagcttatt ttcgaagaag ctatttctgg
    37681 aacacagtt
//
LOCUS       DAXLPY010000020        36706 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.020, whole genome shotgun sequence.
ACCESSION   DAXLPY010000020 DAXLPY010000000
VERSION     DAXLPY010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.020"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..300
                     /locus_tag="ACF3UF_001142"
     CDS             <1..300
                     /locus_tag="ACF3UF_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3671288.1"
                     /translation="DGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKEN
                     RKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(653..1501)
                     /locus_tag="ACF3UF_001143"
                     /pseudo
     CDS             complement(653..1501)
                     /locus_tag="ACF3UF_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1654..2766
                     /locus_tag="ACF3UF_001144"
     CDS             1654..2766
                     /locus_tag="ACF3UF_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFD3671289.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(2844..3137)
                     /locus_tag="ACF3UF_001145"
     CDS             complement(2844..3137)
                     /locus_tag="ACF3UF_001145"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFD3671290.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3305..3619
                     /locus_tag="ACF3UF_001146"
     CDS             3305..3619
                     /locus_tag="ACF3UF_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFD3671291.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3640..5619
                     /locus_tag="ACF3UF_001147"
     CDS             3640..5619
                     /locus_tag="ACF3UF_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3671292.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5632..5958
                     /locus_tag="ACF3UF_001148"
     CDS             5632..5958
                     /locus_tag="ACF3UF_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFD3671293.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            5974..6492
                     /locus_tag="ACF3UF_001149"
     CDS             5974..6492
                     /locus_tag="ACF3UF_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671294.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6492..7844
                     /gene="celB"
                     /locus_tag="ACF3UF_001150"
     CDS             6492..7844
                     /gene="celB"
                     /locus_tag="ACF3UF_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFD3671295.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(7928..9433)
                     /locus_tag="ACF3UF_001151"
     CDS             complement(7928..9433)
                     /locus_tag="ACF3UF_001151"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFD3671296.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9525..10115)
                     /locus_tag="ACF3UF_001152"
     CDS             complement(9525..10115)
                     /locus_tag="ACF3UF_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3671297.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10294..11940
                     /locus_tag="ACF3UF_001153"
     CDS             10294..11940
                     /locus_tag="ACF3UF_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3671298.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            11989..12708
                     /locus_tag="ACF3UF_001154"
     CDS             11989..12708
                     /locus_tag="ACF3UF_001154"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFD3671299.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13187..14134
                     /locus_tag="ACF3UF_001155"
     CDS             13187..14134
                     /locus_tag="ACF3UF_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671300.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14146..15066
                     /locus_tag="ACF3UF_001156"
     CDS             14146..15066
                     /locus_tag="ACF3UF_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671301.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15107..16564
                     /locus_tag="ACF3UF_001157"
     CDS             15107..16564
                     /locus_tag="ACF3UF_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3671302.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            16909..17523
                     /locus_tag="ACF3UF_001158"
     CDS             16909..17523
                     /locus_tag="ACF3UF_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFD3671303.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17516..19240
                     /locus_tag="ACF3UF_001159"
     CDS             17516..19240
                     /locus_tag="ACF3UF_001159"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3671304.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19237..20688
                     /locus_tag="ACF3UF_001160"
     CDS             19237..20688
                     /locus_tag="ACF3UF_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3671305.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21161..23314)
                     /locus_tag="ACF3UF_001161"
     CDS             complement(21161..23314)
                     /locus_tag="ACF3UF_001161"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFD3671306.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23316..24362)
                     /locus_tag="ACF3UF_001162"
     CDS             complement(23316..24362)
                     /locus_tag="ACF3UF_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3671307.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24512..25801
                     /locus_tag="ACF3UF_001163"
     CDS             24512..25801
                     /locus_tag="ACF3UF_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFD3671308.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            25814..28516
                     /locus_tag="ACF3UF_001164"
     CDS             25814..28516
                     /locus_tag="ACF3UF_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFD3671309.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28501..29358
                     /locus_tag="ACF3UF_001165"
     CDS             28501..29358
                     /locus_tag="ACF3UF_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3671310.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29429..30286)
                     /locus_tag="ACF3UF_001166"
     CDS             complement(29429..30286)
                     /locus_tag="ACF3UF_001166"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD3671311.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            30497..32668
                     /locus_tag="ACF3UF_001167"
     CDS             30497..32668
                     /locus_tag="ACF3UF_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFD3671312.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            32736..33077
                     /locus_tag="ACF3UF_001168"
     CDS             32736..33077
                     /locus_tag="ACF3UF_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFD3671313.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33353..35107)
                     /locus_tag="ACF3UF_001169"
     CDS             complement(33353..35107)
                     /locus_tag="ACF3UF_001169"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671314.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35118..35954)
                     /locus_tag="ACF3UF_001170"
     CDS             complement(35118..35954)
                     /locus_tag="ACF3UF_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFD3671315.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(35956..36639)
                     /locus_tag="ACF3UF_001171"
     CDS             complement(35956..36639)
                     /locus_tag="ACF3UF_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFD3671316.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11843 a         6446 c         7481 g        10936 t
ORIGIN      
        1 gatggcttag caccaggagc atatcagctg gtagaaactc aagcgccaac ggggtatgaa
       61 ttggatgcga caccagtaac tttcaagatc gaaaaagaac aagaagtggc gatcttttta
      121 acaaaagaga atagaaaagt tgctgatagc tcagatataa gaggaaacaa tccaacaagc
      181 agtggaaata agcatcttcc aaaaactgga gaaaccatca ttagccagtt tatattgtca
      241 atattgggtg tgctacttgt tttcatcagt ataaaattta gaaagaaacg aaatatatga
      301 gctaaaataa aaaattgaat aagcatagtt tttaaaatca actagtaccc atcaattgaa
      361 tggaaactac cgattttaga aggggtatac aaacaaatat tagtatcgga gtagagaagg
      421 ttgaacccaa ccagtaaata agtaaagaca attttgtgct gcgttgagaa gtgaaaaata
      481 aacctttgta gtaatactag ttaataaaaa atatacaaaa acactgcgaa aatcattctt
      541 gagtttcgca gtgttttttg cctaatgact caagtttatt gggtaatact ttgattttct
      601 ttctacaaat aatcagcgat cagttgtaat tttttctcta gttttaatgg ctctttgtca
      661 ataaggagaa aaacaagtcg ggtcttttgt ctcggaaagc ttcaaccaac tcgtgaataa
      721 aggttacgcc tccttgaaag gcgtggaaaa accaagtaat cgatcaatca ccaatttcgc
      781 atttggtaga acatgtttgg tgagctgaaa gtaggtggcg ttcatgtctg taactaagaa
      841 ttctatttct ttaggattag tgcagctaag gaaatagttt gttaatcgag gaattttttg
      901 tgtaggtaaa ttttctcgat taatttttct gtctcgccat ccgcggaaat aaaactcagt
      961 ttatcctcaa cggaaacgtg agaacgaaat tcacaaccct caacactcaa gacagaattc
     1021 ttttggaaga ctttggtaaa tagcttctca actctttcaa tgtgcgaata acggttgtca
     1081 aagataccta acaacttttc gaaataaaaa ataacgacac tttttcagtc agtaaagaag
     1141 tgattttatg tctgacatga tttgaaatcg agtgccttgg acggataaaa taactttgag
     1201 cgttccaatg gcttcgacag tttttacagg tatagcgctg cttttttagg cgtataacca
     1261 ttggcatatg attatattat tcaaagtgga caatggtttc cttcttcttg tttttcacca
     1321 ccattaattt cctatttcca tctaccacag cagaaccaca atttctacag acacatggag
     1381 cagggaagag aactgcagca acgatcaatg tttttttctt ctgtaaggtt tcgtaagaga
     1441 cctctgtaat catcaaattt ttgtctattg atctcagaat ttttttgata gaaccattca
     1501 taaagcatat cgttctctca gttgtttatt ttgtggtgat ttaatcatac aagaaaacga
     1561 tatgtttttt tataaaaaca tgaataggaa aaatagttga caagaaaatg acaacgccat
     1621 atgatgttcc atagtattta caacctgtca tagatgactg taaaaaataa aagtaaaaag
     1681 aaaggacgac aacaggtgga tttttatcag tctctacaac tagatccgtt tattttaaaa
     1741 caaaaaatac gagaagcagc ttctaaaaaa gaaaagtgca tgtatatttg ttcattgttt
     1801 ttacgatcat tattcatcgt attgtttgcc atttgtttta tcattataat tacaacatta
     1861 tttgaatcga agcataaacc atacgctgtg gttttattct gtatgttgat gagtattcgt
     1921 tttgttgact ttggttataa gatttcccat tcgatcatag gtttagcaat cgtcatgttc
     1981 tcactattag tagcaccgta tgtccagctg atcaaatggt cagttatggg catgttgatt
     2041 cattttattt tactaagcag catattaatg gcaaccgcta gtgatcccaa aatggggaat
     2101 gcttctttgt acggcttttc atatctcttt attgtttatt cgttacctaa agattcgttg
     2161 aacaagaatt tctttacaca aacaagtagc ttattatttt tgtttttttg ttggttttca
     2221 gttcttcttt acagaaaaca tcgagaaaag aacaaagaca aaagcttgtt taaagagatt
     2281 tttttgaaag gcatgtattc gcaggaaaaa atttggatgc tcatctatgc atttggcatt
     2341 agtcttttga tcgttgcagg agagtatgtc ccttttcagc gattgatgtg ggcagggttt
     2401 gcattttctt ctattgtatc tagctatgga ttgatgtcga ttggtttcaa agaacgagca
     2461 gtagaccgaa tcattggctc attgattgga tgtgttttat ttattggtat cagccaattt
     2521 attcctttta actgggtcgg tatattaggt ggtctagctt taggtgtttg ttctacctat
     2581 agatataaaa cagtttttaa ttcttttggt gctttggcaa tcactgccag tttattcggg
     2641 gttccaggag cagtaacgat ccgcattttt gagaatatcc ttggggtatg tttaggaatc
     2701 atgtatattg gggtgactga aatacttatc cgaaaaataa gagaaaaaca cggtttgaat
     2761 cattagatga gatcgaataa aaaataagga aaaagtgaag atacacatgg atgataaatt
     2821 gctatcattc catgtgtatc tttttacggt aaatcagtga aacgttcgac tttcattttt
     2881 aatttatact ttttacggag ttcgtttatt tgagccatca tttcggattt gtgatgcttt
     2941 tcgattgctt cttcatcttt ccaacggtcg atcagtaaaa gagattctgg atcttctagt
     3001 ggaaagtaat agtcatattt ctcgtttcct tcttctgcac gaatcgcttt gacaatgttt
     3061 ctttcgacca tttcttctgc aaattttctg gcttgtccat ttgtacttgt atacaaaata
     3121 ttcactgtga tactcactaa atcccctcct gaaaaaattc tatcactagt atatcacggt
     3181 gccagaaatt attattcaag atatgataca cattttttcc gcaatgctac ggaaatatat
     3241 attttgaata gaaaacgctt acaagatatg cttggtttat aaaaataaaa ggagtgattg
     3301 atttatgaaa aaagcattga ttatttgtgc ggcaggaatg tcatcctcga tgatggcctc
     3361 aaagacaacg gatttcttta agcaaaaaag agaagaggta ctcgtagatg cagtttcagc
     3421 tacagaaggc gataatatga ttaagaatag tgattttgat ttatttctga tcagcccgca
     3481 aacgacgatg tttttggata aattcaaaaa attaggagaa tctgttggaa agcctgttgt
     3541 tagtatccct ttccaagcgt atgtcccaat ccctacaggc atccagaagt tagcagaggt
     3601 gatcgaagag aacatatgat ggaataggag tggatgataa tgaaacagaa ggaaaaattg
     3661 ctgttgagat atttgattga tcacaagaag gagtatgtca ccagtcaacg tttagcttct
     3721 gaattgttat tatctgatcg gacaatccgt aattacttgc agcggatcaa agagttagta
     3781 gaaaaaaacg gaggtaagat cattgctaaa ccaggttatg gctaccaact gcatatttta
     3841 caaagactga catttgactt gtttttgagt cggcaagaaa tagtacctgg atatgctaga
     3901 gaaccgcaag gattttatga gtccgaagat cgacaaaagt atatattgaa ccaattgctt
     3961 ttggaagatg ccattctttt tatggatgat ttggcagaag agctttatat cagtcgttcc
     4021 agtttgacaa aggacatgca agaaatcaag gagcgattga ttccatattc actaaaaatc
     4081 gtttctaagc atggtcaagg gacatggatc gaaggggaag aaagaaatcg acggcatttt
     4141 atcatggata ctttttttgg aaaccattat ggaaattcat tgaaagaata tttagggcaa
     4201 agccgttttt tcccagacat cagttttgaa gagctagtca ttatcattct cgatgaaaca
     4261 agagaagcta agttaaaagt ttcggatttt atcatacaga atctgacttt acacttggct
     4321 ttggggatca aacggctccg agaagggttt gaaatcaagg aattaggcat cgaacaagaa
     4381 gtttctaagc gagtagagta tcaagtggcg cagcggatcg ttcaacgtat tgaggtaatc
     4441 gcaggtgtat cgtttcccga agaagaaatt gcttatttga cattacatct catggctaag
     4501 tcgaatcaca aagaaaatca aaatgatcag gaactatcaa aggaattagc gaaagttctg
     4561 aaaagattgt ctcaggaatt tcatttttca ttagtagagg atctccagct tttcaatgga
     4621 ctactcgatc atttgtcacc gatgatgatt cgattgagcc gaggtattcg cattgagaac
     4681 ccattgactg aggagataaa gaaagaaaat cccaaagtct ttgacgcagt aaaaaggcat
     4741 ttcagcaaca tgccggcttt gaaaaactat accatcaatg aagatgaatg ggcctatttg
     4801 gctttgcatc tcatggcggc attggaaaaa gaaagagctg cgcataaact acatgcattg
     4861 attatctgtg caacgggtta cggcagtgcc caactattaa agaatcgcgt agtcagtgaa
     4921 ttcggtaaaa atattacagt ggtaagtgta aaaggctatt atgagatcaa tgaaacaact
     4981 ttaaaaggaa tcgacctgat tatttcttct attgatcttt cgacaatgtt tttcaaaatt
     5041 ccagttttac atgtcagtat ttttttgaat gaagatgatg ttcgtaaaat acgaaaggta
     5101 gttggagaat ctatacccta tcattcctca gatagaccga taccagcatt ttctctacag
     5161 caaaaaaagc agatttacac cgaacagttg tctgaaaaat ttttcaagac ttatacgtac
     5221 gaaccgaaaa aggaagaaat tcttcatgat ttgctgcaaa agctgagcat aaatgaagaa
     5281 gaaggatata taagagaaat gcgaaagcag atccagcaac gtgaaaatat gggacaaatc
     5341 atattcagtg atacagtggc agtcccacat cccgctgttc cagttggaat cgaaacaaag
     5401 gtagccgttg cattgattcc ttctgggatg cagtgggatc aatatcaaga aattcatttt
     5461 gtttttttag tttcgccttc ttatgtcgaa aatgaaggaa ttacggtcgt gactaaagca
     5521 atcgttaggt tagttgacca gctaaaagta cagcaggaaa tcttagctga acctattttt
     5581 gagaatttca gcagtaaatt tatcaaactg atcgaataag gaggaaaaca gatggctgaa
     5641 aaaataaaca gtgaaacact acaagtgact tcttttgata tcattttcca tagcggaaat
     5701 gcacggacac tgatacatga agcatttcgc tcgatgcgta aagagatgtt tgaagaagta
     5761 gaagagaagt tgcgacaagc aaatgaagag attcttcatg cgcatcagtc acaaactcaa
     5821 cttctgaaag aatatgccag cgggacaaaa atagaaatgg aaattatcat ggtccatgca
     5881 caagatcatc tgatgacgac gatgacatta ttggaagttg cacaggaaat gaattatttg
     5941 tatcaaaaaa ataaatagaa aggaaggatc attgtgcagg atacagtaaa aaggaaaatc
     6001 gaattagaaa aaaagcaact tagtttgaaa aacatgtatt tcaatcgtta tctaatcgta
     6061 cgttacctga ctgccttttt ctttttcatg aacatgcaat ggatgattct gcttctatca
     6121 gctaaaagtt taggaagtag tttaccgatg attctgattt tagctatttt gcctgcagta
     6181 ggagaacaag taaagcttta tcgaaaacac caaacgaacg ttccatggac aaagtggtat
     6241 tttttgttcc agagtgtctt taatttatta gtgattccag tgttgtttac ctcaggattt
     6301 acattcttgt atccttttat ggcaaataac aatggaggac agttatttgt tttcattctt
     6361 gttgtaagcg gtatttttgc cagtgcattt atacagtatc gtttaaagaa aatttcactc
     6421 aaccaagacc aacagtatat ccgtattaaa caatatgaaa aagcgttata tttaggaaag
     6481 gagaataact aatgtttgat tttttgcaga aatacctgat gggacctatg gggaaaattg
     6541 cgcaacttaa aatcgttcgg gctgtcatgg cagcggggat ggcttctatt cctttcacga
     6601 ttgtaggctc gatgtttttg gttttaaata ttttgccatt accgttccca tttttagaag
     6661 gattttttaa tgcaactttt ttcaaagtta gtgacttgta catgatcgtc aatacaatga
     6721 cgatggggat tttatctatt tactttgcca ttgtgtttgc ttatgaatta acgtcaattg
     6781 aacgagatga acaaaaatta aatgttaatc cgctcacggg ggcattacta tctgtttttg
     6841 cattctttat gtgtatccct gaattgatca tgactgatgg taaaatcagc ttgattgctt
     6901 ctatcaatga gacagaaact gtagtaaatg gtattaggat gggctctttt gtcgaacgtt
     6961 taggaacttc aggaatcttt acagctatta ttatgtcgat tattgcggtc gaattgtatt
     7021 gtatgtgtgt caagagaaat tgggtcataa aaatgccaga tgttgttccg ccaggagttt
     7081 ctcgttcttt cactgctctg atcccaacat ttgtcattgc gtttgtggtg atgatcatca
     7141 atggattatt agttgcacta ggaacggata tcttcaaaat gattgctatc ccatttgggt
     7201 ttgttacgca gttgacgaat acatggcttg gtgtcatggt gatttatttc ttgatccatg
     7261 cattgtggat cgtagggatc catggagcga atatcatcac ttctttcttg accccgatcg
     7321 tattagctaa tatggcagct aacgcacaag gcgcaaatta tccgttggca ggagaattca
     7381 acaattctta tgtaaccgtt ggtggatcag gtgcgacttt aggattgatc atctttattg
     7441 cattcctcgc gaaatctgat cagctgaaag tgttaggaaa agcctcactt gtaccaggat
     7501 tattcaatat caatgaacca atcattttcg ggatgccaat cgtctacaat ccctatttag
     7561 cggttccgtt tttcttagct ccgatggctt ctgctacact cgcttatttt gccattcggc
     7621 tggaaatcgt caaaccgatg cttgcacaga tgccgtggcc ttcaccagtc gggatcggag
     7681 catttgttgg tagtggtggt gattggaaag ctgctgtgtt agcagtcatt tgtgcaatca
     7741 tcgcattcat tatctggttc ccatttatca aattctatga taataaatta ttaaatgaag
     7801 aaagagaaaa ggcagcagaa ttagctagtg aaaagttaaa atgatttcta agaaaaaagg
     7861 aactgtgaca aaaaatcaca gtcccttttt ttcttagaaa tgggaaacca ctagtatata
     7921 aataccatta ttcttcaatc aaccgcttca cgattgcata atccccttca taaggttcat
     7981 ctacaccatt gattttttga tagggatcca cgccttttcc cgcaataacg actgaatctt
     8041 gcggagcgct ttctgctaaa gcgcgtcgaa tcgcttcagg acgatccatt tcataatgaa
     8101 cgatcaaatc tggattagta attgcttcat tgatttcttc cgcgattttt ttcggatctt
     8161 caaatgctgg gtcatctgcc gtcaaaaagg cgatgtcagc tgtttctgat agcacttttc
     8221 caaaatcatg tcgacgggag attgctttgt ttcctgggct gcctaataca acaattacac
     8281 ggccatctgg atgttcattt ttggcaaatt ccagcaatgt tttcaagctt agataattat
     8341 gtgcatagtc cacatagaca tgcgctccat tggattggat caattgatcc attcggcctg
     8401 gtacacgagc ttcttttaat ccgtcttgtg catcttgact ggaggcacct gttagtgctg
     8461 cggcaatgat cgcactggct gcattttctt ggttgaatcc tccagccagc aaaatatcat
     8521 aagcagtatc gcagatagct aagcgatctt catgagaaga taaagtaaaa ccgtgagtac
     8581 ctttatctga acggatcact tgataattgc tttcttccga acgaccataa gtgatcgttg
     8641 gaatctggaa tagatcggct gtttccctaa gtaaatcaaa atagtcactt tcatgattta
     8701 aaacaactgt ttttgaattc aagatcaatt gtcgcttgca atagaaatag tcatcaaatg
     8761 tcggatgttc gatcggactg atatggtcag gcgagatatt caagaagatt ccgacatcta
     8821 aagtcaagcc gtatacgcgt tgtgttttgt aagcttgtga agaaacttcc atcactagat
     8881 gagtcatacc attttcaact gcttctgaca tcatacgata taaatctaat gactcaggcg
     8941 ttgtcaaatg ggatttgaaa tatgttttgc catctaacgt tgtattcata gtagaaagca
     9001 atgctgtttt tttatttgtt gtgtgatcca agattgcttt tgtaaagtac gcagcagttg
     9061 ttttaccttt tgttccagtg aatccgatca ctttcaattt attttgcgga tagtcgtaaa
     9121 aagccatagc aagaagcgcc attgctttac ggatatccgt tacgatgatt cctactgctg
     9181 aattttcgta tggttgttct gatacataat attgaatacc ctgttcgatt gctgaatcca
     9241 aatattcttc tttgaaattc attcctttac agaaaaacaa agtagaagca tcagcttttc
     9301 ttgaatcata acttaactga agaaattcag ctttttctgg tacatcaaga tgccagcctc
     9361 ttgttgaaac aaattctttt aatagatttt cttttaatag taaatgacgg atgtcttcta
     9421 aagagaagct cattgattga tccctcgctt tattcaattt cttggtttat tatagcacac
     9481 tctttttaat atatcgtttg tttccgctat gacaaaatcc agctttattc aaattttctt
     9541 gacacagggg acaagcggat gagtattttc ataaacaatg aactgactgt aatagatagg
     9601 agaacgaata gtgtctccaa caatccaaaa acataataat tcaaaaagac gataagacta
     9661 ttggtaagta aaagtccttg cggcattgga agccgaaaaa atttgtggaa aataatcggc
     9721 ggtatcgtta taccgccatt tgaggccccg actgtgtaca atgtgtaaac cccaagactg
     9781 aacaaaagac ttcctgaaat cagtgaaaag aaatgtgagg agatcatttc cacttttgga
     9841 acaatctcta aaacaacagg aaaaagcaga cttcccgcta cagtcttaaa aaatactgat
     9901 tttcctaata ggacagcggc tagaagcagc atcataagat tgatgctcca aacagtaact
     9961 gagcgttgga tagaaaaggc cgtttcaact aaatgtccga tggcgcccac tccggcggaa
    10021 gctatatcgt gagggagcaa gaaccaattc aatccaactg tgataaagaa aagacctaaa
    10081 aatataacgg gtagtttttt tatttcttgt gtcattgata tctcctataa atgttagcca
    10141 taaaaggctg tatatttctt tactttacca aaaaaacgaa accgaattca aaaaaacaat
    10201 tgttcttata aaagttatat aaaatcgatt gccagtttct gttttaccaa ttaaaatgat
    10261 agtaatgttt tgtagaaagt tggaatctga ccgatggata atcaaagaaa accagcatta
    10321 gatcaattaa caccgcaaga aaaaatggca cgaggctctg cttggatgac cgccagtaat
    10381 atcatttcaa gattgctagg cgctgtctat atcattccct ggtatgcttg gatgggcgaa
    10441 aatgctaagg ctgccaatgg attattcaat atgggataca atatatatgc attgtttcta
    10501 ctgatctcta cagcaggaat acctgctgcg attgcaaaac aaactgcacg ctataattca
    10561 ttgaatgaat atggcacttc acgacgatta tttatccgtg cattacagat gatgggcggg
    10621 ctaggcctgt tgtttgcttt gttcatgtac atcgcctctc cttggctagc tcatgcttct
    10681 ggtggcggag aagaactgat tccaacgatg cgttctttga gtatcgctgt attggttttt
    10741 ccttgtatga gtgtgatacg agggtatttt caaggcaatc aagaaatgat gccttatgcg
    10801 ctgtcgcaga ttgtagaaca ggtggcacgt attttttata tgctattggc tacattcatc
    10861 atcatgaaag tcatggatgg tgactatgtg acggcggtca cgcaatcaac tttcgcggca
    10921 tttatcggta tgctagcaag tattcttgtc cttttgtatt ttttgaagaa acatcaagcg
    10981 tatacatcgg cgtttattca ctacagcgaa aacaaaataa atattgcaac gaaggaattg
    11041 ttgttagata ccgttaaaga agcgattccg tttattattg tgggttcagg ggtaacgatc
    11101 ttcaaattag tcgatcagtt cacttttatg aagatcatgt ctgcatccac cgagtattcc
    11161 aatgcacagt tactggatct tttttcgatt tttagtgcca atccagataa gttgacgatg
    11221 gtagttattg cattggcaac atcgatcgcg tctactgggt taccgttgat tacagaagct
    11281 gttacgttga aagatcgagt aggtctggca aaattgacaa gcggaaattt acagttgttt
    11341 tcatttttta tgtttccggc gacatttggt gttatgttac ttgcctatcc gctaaataca
    11401 ttattttata caccggattc tctaggaagt aatgtactga tccaagcaag ttttgtagga
    11461 ctcttcctag gactatatat gctagtttcc aacatgctgc aaggaatgtt tgaaaacaag
    11521 gcggcaatta attatttggt tattgggttt ctagtgaaac tccttcttca atacccagcc
    11581 attcgtttat ttgaagtata cggcccttta ttggcgacaa tgatcggatt tgctgtgtct
    11641 tgtaccttga tcttaaagag aatccatgaa gtagcccgct ttaaaccaag ttttgtctgg
    11701 cgcaggacat tgctgatctt tattcttacc ttgattatgc ttttggcttc gtggatcaca
    11761 aagatgattt ttggtgcttt tttaaacgaa gatagcaaat tccagtctct attgttgatt
    11821 cttgtagtag caggtatagg ggctttagtg tatggttatt tagctttgaa aatccgcttg
    11881 gcagaaagac tactaggacc aggaatagcg cgtttacgac ataaattaaa aataaaataa
    11941 gtgaatcaga agagctagat tgatgctctt ttgaaatggg ggaaacgcat gcgtttagat
    12001 aagtttttag cagatatggg acttggcagc cgcaaagaag tcaaaggatt gatcaaaaaa
    12061 ggaacgatcg aagtcaatgg acaagtggtg aaaagcgata aagcgcaagt aaatgaattc
    12121 gaagatgcgg ttacttattt aggagaaatc attacgtatc aaaaagattt ttactacatt
    12181 ttgcataaac ctgcaggagt catttctgct actcaggata atcatgatca aaccgtaatc
    12241 gatttattgg aagaccagga ttatcgggaa gatctttttc cagtcggccg attagataaa
    12301 gacacagagg gcctcttgat tttaacgaat gacggggtgt ttgcccatca gttactatca
    12361 cctaaaaaac atgtggagaa agaatatcta gctgaggtta gcggtataat gacagaagaa
    12421 gatatccgtt tatttgcaga aggactgatt attgatggcg atgagcagac attgccggca
    12481 aaactccaaa ttgatcaagt agatcaagag acagaaactt caattatccg tctgattttg
    12541 catgaaggaa agtttcacca agttaagcga atggtcaaag cagtaggaaa agaagtctta
    12601 tatttaaaaa gaatccgtat gggaaaattt tggctgccta aagatttgaa taaagggcaa
    12661 tatcgaccca tgaccaaaga agagctagaa caagtgagag aaaaataatt gaatggatag
    12721 ctaaaagaat aagcagagta gttgtagcgc catctgaaaa gcagacttgt ccgtctgact
    12781 ttcggatggc ttttttgtga aatttcggct tatttccgta gaagctactt ctggaacacc
    12841 gtttgttcgg aataagggac tgtgacaaga cttttgttac agtccccatt gttccttgtg
    12901 actcagagtt agatagtaag gacacgatct ccctaatact caggccaaaa cgctgaattc
    12961 acaacctctg ataaacggtg ttcaatcagc tgaccctcgg tattagctca aaaaacggca
    13021 aaatatgagg aactattttc ccgttttttt ctctaatact caggccaaaa cgctgatttc
    13081 acaacctctc ctatactttg tttcattttc cctatacttt gtttatttat tctcattatt
    13141 gaaagcgcta taattacgtt gcgaatgaat cgaaaggggt ttttagatga aaaaacgaaa
    13201 ggggttcaat cattttttta tgaatctatg gcgttataaa gcacttgtcc tgatggctgt
    13261 accgggtatg ctttggatga tttttttctt ttacatacct gtaatggcga atgtcgtagc
    13321 attcaaaaat tttcatattt cagcagatgg gttcttggct agcttgaggg aaagtccttg
    13381 ggtgggttgg gaaaatttca aatttttatt ttcttcggat caagcatttc tcatcactaa
    13441 aaatacaatt ttatataatg tagcatttat ccttttgaat ctgctgatct cagtcgtatt
    13501 tgcaatcatt atgagcgagt tgagaaataa acgactcgtt aaagtttatc aaacgatgtc
    13561 cttactacct tattttctat cttgggtcat tatcagttac tttgtttacg cttttttaag
    13621 tcctgacaaa ggaatattca atcagtggat cactggacat ggaggagaag ctgtcaattg
    13681 gtataatgaa ccgaaatatt ggccgtttat cttggtgttc attggtacat ggaaagggat
    13741 tggttataac agcattattt actttgcatc tgttatggga atcgatccga cttattatga
    13801 agctgctatg gttgatggag ctagcaaatg gcagcagatc aaacatgtga cgataccaca
    13861 acttattcca ctaatgacga ttttaacgat tttagccgta ggaaacattt tccgagctga
    13921 ttttggcctg ttttataaca ttcctaggaa ttccggtgca ttatatgatg tgactcaagt
    13981 tttggatacg tatatctaca atggcctgac atccacagga gattttggta tgacggctgc
    14041 tgcaggactt taccaatcag ttgtcggctt tgtcttgttg atgatcacaa atacgatcgc
    14101 ccgacgtttt gatagcgatt ctgcattatt ctaaggagga aaaaaatgaa aaaaaagaaa
    14161 gtggagagag tccaagtccg ctctttcaat aagacggcta attttttctc taatataatg
    14221 attgcactct ttgctatttc ctgtattttg ccatttatat ttgttatcgc catctctttt
    14281 accgatgagt ccatattgtc gactcacggg tacagttttt ggccagaaaa gttcagtata
    14341 tttggttata cgtacttgtt cgaccagatg caggataaaa ttttccaagc gcttttcgtc
    14401 actgtacttg ttactgtttt aggtacactg atcaatagca cggctacttc tttatatgct
    14461 tatgcgattt cacggtcaaa ctttccattc cgtcgttttt ttaccgtttt ttgtttgatt
    14521 acgatgttgt tctcaccagg gatggtggcc aattatcttg ttatgacaaa tcttcttcag
    14581 ttaaaagata cgatttgggc attgatcttg ccaatggctg tcagtccctt caatattatt
    14641 gtgatgcgca cattctttaa acgttcggtc tctgattcga ttattgaatc ggcacggatc
    14701 gatggagcta gcgaactgcg aatatttgtt cagatcgttt taccgttagc tgttccaggt
    14761 attgcgacaa tcagtttatt tgccgcattg ggttactgga atgactggtt caatgcttta
    14821 ctatacatcc aagatgataa gctagttcca ctacagtatc ttttgatgaa aatccaaagt
    14881 aatattcaat atctgacaca aaattcagga gcaggaagcc aattgacagg cggattagcc
    14941 tcagttccag gagaatctgc cagaatggcg atcgtagtca tctcgacgtt gcctattgcg
    15001 atcagctatc catttttcca gaagcatttt gtcaaaggtc taacaatcgg cggagtaaaa
    15061 gaataaagaa acaaaaatat aaatcataaa attaggagga agaaaaatga agttatggaa
    15121 gaaactagcc tttacaggtg tttcagcgtt gttgttggga acattagcag catgcggagg
    15181 ttctggttct aaagaccagg cagaagctag caattcggac actttgcaga tgtatcaaat
    15241 cggagataaa ccagataatt tcgatcaatt gatggaagta gcaaacaaac gaatcgaaaa
    15301 agagatcggt gtaaaagtca atatcaatta cattggctgg ggcgattacg aaaagaaaat
    15361 gaacgtcatc atttcttccg gggaaaatta tgatatcgcc tttgcgaaca actatgtttc
    15421 caatgcccaa aaaggagcct ttgctgattt gactgaatta gcgcctaagt acgctgaaaa
    15481 agcttataat gatttagatg aagcatatat taaaggaaat ctggtcaatg gaaaattata
    15541 tgctttccca gtcaatggaa atgtctttgc tcaacaagta cttactttta acaaagcttt
    15601 actagataaa tacgatcttt caattgatgg aatccaatct tacgctgatg cagaaaaagt
    15661 cttgaaggaa ttccatgaaa aagaaccaaa cacggcagct tttgccattg gacaaggctt
    15721 caaagtccaa gggaactttg attatccttt agggaatacg ttaccatttg ctattgatct
    15781 ggatggagat gattcgaaaa tcatcaacca atacgataat gaaacgtata tcggactgtt
    15841 acgtacaatg catagctggt acaaacaagg actcattcca agtgacgctg caacgagcaa
    15901 taaggattat ccactagaag gaaatacttg gctaatgcgt ggagaaacac aaggaccgta
    15961 tgattatggc gatacaattt tgacaaatgc agcaaaacaa gaacttgtct caaaagcaat
    16021 tactgttcca ctaaaatcta cagctcaagc acaaatggca aattttgtcg tatcaaatac
    16081 ttcaaaaaat aaagaaaaat cagtagaact tctagggctg cttaacagtg atccagaatt
    16141 attgaatggg cttgtttggg ggatcgaggg agaagcatgg gaaaaagtcg atggttcaga
    16201 tgataaaatc aaattgctag atggttatca gccaaataca catatgtctg cttggaatac
    16261 aggaaacaac aagattctat atacacaaga gtctattacg gatgacatga ttgccaaacg
    16321 tgatcaatcg attgctgatg cagaaacttc accgatttta ggattcagct tcaacactga
    16381 cagtgtcaaa acagaattaa gtaatatttc taatgtcatg aatcaatatt tagatggatt
    16441 gaatacaggg actgttgatc cagatgaaac attaccgaaa ttgaaagacg ctttggacaa
    16501 ggctggctat gataaggtat tgaaagaaat gcaaaaacaa tatgatgagt tccgacaaga
    16561 ataataatga ataaagacaa aggggttgtg acaaaagacg tgtcacaacc tcttgttccg
    16621 aataaacggt gttcaaaagc cagtttctcg gtattaagct aaatatatgt aaaaatgtgg
    16681 aaagccatat tcacaaaatt tttcttacta ctcgaaacta agcggctatt tcacaaactc
    16741 ttggtaaacg gtgttcaatc agctgaccct cggtattcgc tcacaaaacg acaaaatatg
    16801 aggaactatt tttccgtttg tttctctaat aatcaggtca aggtgctgat tgcccaacct
    16861 ttttttgtat aatgagaaag tataaactta atgtttggag gagaagatat gttagggaag
    16921 gttttggaag agttatttat ccggatctgg gtcattataa aactaacctt gtatttctgg
    16981 atatatacat ttgccggcgg gatcatcttt ggattaggtg cggcatggaa aacagtcaat
    17041 gaactatttt atttgtacgg attcgagtat aaagaaatca caataaaaag aggctggaat
    17101 atatataaaa gaaatttttt aagaggcaat ctgctattta gtttattttt atctggtact
    17161 gctttattga gttacaattt atatttatct gttcaaatca aagggctcat ttttttagct
    17221 attgatttta ttttactttt tgccttgctc tgcctatttg ctacttatca atacagtatg
    17281 attttagata gtgaatatac gatctctgtt cctaatctgc taaagctaag ttttatttcg
    17341 gttttttcca gcttttcgtc ttttctaaaa ataattattg gtagcggtat aattttaggc
    17401 gtgacttggc aattcaaagg attgatcctg tttggtgtca ttggtctttt gacggtttgg
    17461 aatggtacga tgacaacaca ttggcgtgaa gaattagata aacagttgga aagttatgaa
    17521 taagtttcgg attctatttt caaaaggaac cttactaaat cgtctgttgc ggaaatacgc
    17581 ggttatcatg atcggtgtaa cgatgactgc taccgttatt tttagtatcc atacttggga
    17641 acaaaatcaa aaacaggcag aaaacatgac aagtgatgcc gttcaaagca caagcagaat
    17701 gctgaatgat aaaacaacct tgagtaggat catcaaaaac cagcttgtag ggaattccga
    17761 aaagatcgaa aatgtgacga cctacttaac aaaacccata gatcagtatc tgatgtatgt
    17821 atacgaacag caaaacagta ccgatgaatt agtttctttc ccaaatcaaa tcaaagatct
    17881 ctacgcaaat tatgaagaac taagtgcgat atatatcgtg ttgaatcaac taccggagta
    17941 ttatgaatct tctagagaaa acaaaggtgg ggaaataaaa aaggggacac caaaattact
    18001 agacgccttt tatatcaagt tgcctatcac acaaggagga gctgagtcag gaagtatttt
    18061 tattggtttt caaaagaaag aactagatat gattttagaa aatctaacgt cattcaatgg
    18121 actctcttta tacatgattt ctggaacgac aaatcgacta tacacattcc atgataataa
    18181 aatagctaaa gaaacgtttg aaagacaaga aatgatcatc acagagagtc tgaagaaaaa
    18241 ttcacaattg ccgattgacg atctggaaaa aaacaatttt gttcaacacc aagaactgtc
    18301 tgatgattat cgtatattag ctgtactaga taaaaaaagt gtaaaaatcg aaacgggaaa
    18361 aaatcttgcc ccgctgatca ttggtatcat tattttagac aatatactgc ttatctttct
    18421 ttataaaaca ttcaaacgat attcacagca agtatctatc gtcatgcagg ccatggatca
    18481 aacagcagca gggaatttag agacgcggat cgacataaca aacacggaat atgaactgaa
    18541 ggaactttca atcggtatca acgaaatgtt ggatagcatc aatcagtttg tagaagacat
    18601 ctacaaatta gaaatcaaac agcaagacgc acatatgcgg gcgcttcaag cacagatcaa
    18661 tccacacttt ttatataata cattagaata tatccgaatg tatgcaatca gcgaaggaag
    18721 tgaagaatta gcagatgttg tgtatgcgtt ttccgctttg cttcgaaaca atacgaatca
    18781 agagaaaacg atcactttaa aagaagaact ggacttttgc gaaaaatatg tctatttgta
    18841 tcaaatgcgt tatcctaatc gagtagccta tcattttatg atcgatcctg atttggaaaa
    18901 gatcgaagta cctaaatttg tgatccagcc attagttgaa aattatttta aacacggtat
    18961 tgattttact cgattcgata atgcgctaag tgtcaaagtc ttgcaggaag gcaaacgggt
    19021 aaggatcatc atcaaagata atggaaaagg gatgactgaa aaacggctaa aacagattga
    19081 agaaaaactg tctcatccta aagtggaact tcacggttct atcggtctgc aaaacgtgaa
    19141 tgaacgttta cgtgccagct tcggcagcag ttattatatg tcgcttgaga ataatgagac
    19201 aggtggactg accgtttcta ttacattcaa ggagggatga gcgtgtatca agtgttattg
    19261 gtagatgatg aatacatgat tttgaatggg ttaaaaaaga taattgattg gcaaagttta
    19321 ggctttcaaa tagtagcaac agcagagaat gccaaagaag gactagctgt acttgaacag
    19381 cgacagattg atttagtagt aacggatgtg acaatgccag aaataaatgg actggaattt
    19441 attgaagcgg ctcaaaaaga acgtcataat tttgaattta tgattttatc aggataccaa
    19501 gaattcgatt atttgaaagg aggtatgcaa ttaggcgccg tgaattattt gatgaaaccc
    19561 gtgaataagt tcgaattggt tgaaagcctc aagaaaatca aaacacggtt agatcagcaa
    19621 aatgaacaaa aaaatcaaca agaaatctat caagaactgt tattcagtca atggttgaat
    19681 gaagaattgg atgaaataag tgaagaagaa ataataggac aaataagtga gaagcagcat
    19741 aggatagtat tgattcaact ggcaagaact catgatactc ttatcaatag atggttgcaa
    19801 gaacggcaac aaatctttta ctatcaacga aattacggag accgtgtatt gatcacgttg
    19861 ttgttggagg cagatgaagt tgatggcttc tgttgttttg ttcaagaaaa ctttcctgat
    19921 caggaatggc tgatcagtat cggggaagag acagattctt tggacaaaat ccctgaaaca
    19981 ttccaacaag cgaaagacaa tctacagttg catcaatttt atggagataa agacgagcat
    20041 gttttttacg cagtacaagc agaaacaaaa gatcaaacca tcgatttttc aagtttcaga
    20101 cgcgtgctgc aaaataaaca attggaagtc gctcaaaaaa tgatcactga tttttttgaa
    20161 cagtttcagt tagcagccat gatgccggaa gatatacgat attccagttt tttactgttt
    20221 atggagattc aacgggaatt gattgatctg gaagatgagg aatatttaca aggaatcgaa
    20281 aaaatccatc aggcaaaaac ggtgcaagaa cttcagcagc tacttctgtc attcatcaaa
    20341 aagcatcaga gacagaaaaa gtacagtgac aatgtggaaa aagtaatcgt aatcctgcac
    20401 cagcattatc aagaaccact tacactcaaa gaagtgtcag aaaacctgca tttaaatgtc
    20461 atgtatctag gacagctgtt caaaaaagaa acgaaaaaaa gtttttcagc ttatttgaac
    20521 catttacgta tggaaaaagc gaaacaactg cttttgcaca gtaatcaaaa catcaatgag
    20581 atagcaagtg agattggcta caacaacacc acgtatttct ctaaattatt caagaaaatc
    20641 gtcggcagat cccctaaaga gtaccgagaa aacagtggag aatcataaaa aaaaaagcca
    20701 atgtaatgaa ataacttata aaaaattgtc tagaaatcta attttgggct gttcttatta
    20761 cttgaggcaa ggcagctttt tcatgacctc tcgataaacg gagttcaaaa gccagtttct
    20821 cggtattaag ccaaatttat gcaaaaatgt ggaaagccat tttcacaaaa tttttcttaa
    20881 tactcgaaac taaacagctt tttcacgacc tctccactaa atggtgttca atcagctgac
    20941 cctcggtatt agctcaaaaa atggcaaaat atgaggaact attttgccat ttgtctctct
    21001 aatactcagg tcagaacgct gatttcacaa cctctcaata aacggtgttc aaaagcttgc
    21061 atctgcggta ataagaccaa ccaaacgaaa aatatgagga tctatttttg cttggctgtt
    21121 cttattactt gatgcaggac agctttttca caacctcttg ttaattatag tttgataagg
    21181 aaaaaggcaa atcttttgct tgatatttct tagggtgagg gatgatccct aattggtaag
    21241 agatcgtgcc gcctttcagc aaatcttgat gggtaaaata taatttcgta tattctctgt
    21301 ccatccgttt gattttatgg ataaattgtt gctgcggccg attaggcgtt gcttcaatcg
    21361 tcaattcctt tccatttgac aaaagcaaaa cagccttgtc aattaatggc ataccgataa
    21421 catattcacc ggttccaggc gtgacaggat aaaatcccag actattgaag atataccaag
    21481 cggccatact tccattgtcc tcatctccag ggtaacccat tggagaatcg tcgaaggtct
    21541 gagtcatcaa ctgtttaagc agtggctgtg ccatttcagg ttgtcctata taactgaaca
    21601 agtaaggata gtgaaaactt ggctggtttg aaatagctaa ttgtccaaat tctatcgcgg
    21661 ccatctcact catttcgtgg atctcaaaac catatcctcc tgggtcaaac gttgggggct
    21721 gattgcacag ctcaatgagt ttttctttat atctctcact gccaccatat tttccgatca
    21781 gtcctgaaaa atcgtgataa acagcaaagc tgctttgcca agcacttcct tctgcataat
    21841 cttgtcccca acgattagct gaaaatggtt ctctgaactt gccatcttta tcttttgaac
    21901 gcataaatcc tgactcatag tcaaagatat tttgatagtt caatgattgc tgctgatatt
    21961 tcttcgtcat ttcctcttct tctagtacct tggcaacttg gctaatacaa aaatcgctat
    22021 aagcatagtc taatgtgtga ttgactgatt cgtggtagtg attaggaaca tagccatatg
    22081 tcaagtaatc ttctgttcct tggcgtccat aatttggatg tttgctttga accgtagcac
    22141 ctttttccat tgccgttaga aattcaggca tcaagtctcg tcggatatct tttacagcag
    22201 catctgcaat gaccgcatcg atcaatgtcc caggcataag tccacgttca tcaggagaca
    22261 gccattttgg caaatagcca ctttctctat agctgttcaa aaaaccttcc agcatttctt
    22321 cgtatttttc tacagcaatc aaagaataaa gaggataaac cgttttatac gtatcccaaa
    22381 acccattatt tgtatagaga acaccaggtt ttatagatcg actagtcgta tcatagtgga
    22441 ttttttgccc actaggatca atttcataaa atgtttgtgg aaataaaaac acccgatata
    22501 aattatgata aaacgtccgc aattgttgtt gatcatggtg tgtgagctgt atacgatcaa
    22561 aataggactg ccattgttct tgactgtgag caaggtaagt ctctttgctt tggttttgtt
    22621 ctagttccag gttataagct gcttgttccg agctgataaa agatgtccca aatcggatag
    22681 tttgtttttt tgtctgttca aaatacaacg ggatcgagtc gctatttttg ttggaaacag
    22741 ctaactcatc aattgttaaa ggatattcaa atctcaatat aaaataaaaa gaaaaatcag
    22801 gatcttctga accagcaaaa tgtgtgattt ttccttccac tgtgtaagga tctataacaa
    22861 agagctgatg gcgtcccgga aaggataaaa gtaaaccgct gtcatttttg ctgtaatcaa
    22921 tagataagat tccgccatac atgctaggta tcaatgtaga acagatgcca taacgtaatt
    22981 gacagatcga cagatgagtc gggcaaaata tactttcttc tgggcggtaa gaactttgag
    23041 catggaaaag ggtgttctcc tgtagttttc cattgatcgg cgtaaacagc atatgactga
    23101 aatcacccat ccaaggactt ggttgatggg taagacggta gccttgaaaa acgcggtcat
    23161 caggatgaaa ccaccagctg ccgttttgat ccgtagtttg cggtgcaaaa taattcatcc
    23221 caaaaggaac gccagtataa ggctggcagt tcccattaga gaaatttggc tgattcgctg
    23281 ttgcatgtct agtatctatt tgaccgatat tcattttatt tctcctttgt tgattgtctt
    23341 ttgatgaatg aaactggaaa tttactatcg gatggtcgat cttttgtctc taaccaagtg
    23401 accaaagcat ctcccgcaag cttacctaac tgttcaaaat cttgtgcgat ggttgtcagt
    23461 ggcgggtcaa caagagctgc tgcttggata tcatcaaatc cgataattga aaaatcttca
    23521 gggatatgat aaccatgctg tctcaagaga ttcatggtct ggatagcgac aacatcgttt
    23581 tcacaaacaa aagcagttac ttcatactta gtgatataag aaagcaattc atctaatgtc
    23641 gcgcttttgt catccagtga agtgtggaaa gtcaaaccag ctttgtccaa tgcttcaagg
    23701 taaccaaggt aacgctgtcg aacggattgt ggatgagtct gcgtaccaaa caaataagcg
    23761 atttttgaat gtccctgttc gatcaaataa gaggcagcaa gcgcaccgcc ttggaaatta
    23821 tcggaaagaa cggtaggaaa aggtaactca tagatttttt tatctaatat gacgacaggg
    23881 aattctttca atgaaagctc aaaaagtaag tcaagatgtt gttctgtatc aagagcataa
    23941 taaatcaatc cgtcaaattc attgattagc tcttttgctg ttttattttg tagaaagtca
    24001 agcgtcgtca tcatgacatc aatctgttta tcttgcatca cagggttcaa tcccttgcta
    24061 aaatcaccaa cagacaaatc agcgacatat ggaagaagaa acagaatccg tcgtgttttt
    24121 gtaggagaag caagaatctg ttccggagaa gcggatttaa cgaaactgcc tttcccgcga
    24181 acgcgataaa taagtcctaa ttgctctaat tcagtcaatg cacgtttgga agtgattctg
    24241 cttactttat aggtacgtga aagttctttt tcagttggta gttggctgtc tacaggtaat
    24301 tcaccagtta aaatagccgt ttgcaaatca ttaaatattg tctggtacaa tggttgagtc
    24361 atataaacac ctcttaatga tatatcatat tcaaataata ccataatgga tgaaaaagta
    24421 aataaaaaga tattttttga aagcgtagac ataattggct gtatgaagta taatctttaa
    24481 agatatatca aatagaaaga aggttttatt agtggtttat aaagatatac caaaatcggt
    24541 gcagaaattt atggaagata tcacacaaaa atgtggggat atccatgcgg actgggcaaa
    24601 gaattttaca gcagcatttg ccaatactct gttgacaaca gtcaaaaagc aaaatgacgg
    24661 aaccaccttt ttattgacgg gagacattcc agcgatgtgg ttaagagact ctactgcaca
    24721 agttcgtcct tatttagtga ttgcaaaaga agatgaggaa ttagctgaca tgatcagcgg
    24781 gttagtcaaa aagcaatttt tttatatcaa tatcgatcca tatgcgaatg ccttcaacga
    24841 agaagctaac ggtgctggcc accaaacaga tcatacaaaa atgaacgatt ggatctggga
    24901 aagaaaatat gaaattgatt ctttatgcta cccaatacag ttggcctatc ttctttacaa
    24961 aaatacagga aaaactgatc aattcaatca atcttttatt gaaggtatca aaaaaatctt
    25021 ggacgtgttc aaaacagagc aagatcatga acactctcct tatacatttg tacgagacac
    25081 gacaagaaaa gaagatacgc tgatcaatga cgggcgaggt gcaaaaacag cttttacagg
    25141 aatgacatgg tctggtttcc gtcctagcga tgatgcttgc cgttatggat atctggtacc
    25201 atccaatatg tttgcggtgg tcgtgttagg ttatgtggaa gaaatttttc aaacgatact
    25261 cgatgataaa gaaattgtac agcaaacaca gaaattgaag aaagagatcc aagaggggat
    25321 tcagaatcac ggacgaacgg ttaatcaaaa agggcaaacg atttatgcat atgaagtaga
    25381 tggaatggga aacgccacag tcatggatga cagtaatgtg cccaatctga tcgccgcacc
    25441 ttacttggga tattgttctg aacaagagga agattatctg caaacaagaa gaacattgtt
    25501 gagtaaagaa aatccatatt tctatgaagg aaagtacgca aaaggaattg gatcctccca
    25561 tacgccagaa aaatacgttt ggccgattgc attagctatg gaaggaatga caacgtcaga
    25621 caaatctgaa aaagagcgga tattgaattt acttgtagca actgacgcag gaacacacct
    25681 tatgcacgaa ggattcgatg tgaacaatcc tgaaaattat acgagagaat ggttttcttg
    25741 ggcaaatatg atgttttgcg aattagtcat ggattacttt gatattagag tagaaaagta
    25801 ggaggtatcg taaatgaaaa agaaagtata tatcatttct catagccact gggatcgtga
    25861 atggtacatg gcttacgaac agcatcacat gcgactgatt gaattgatag acgatctact
    25921 agagctattt gaagttgatc cgtccttcaa cagttttcat ttggatgggc aaacgattat
    25981 tttagatgac tatcttcaag taaggccaga aaaaagacag gcaatccaac aagcaatcaa
    26041 tgaaggaaaa ttgagaattg gaccatttta tatcttgcaa gatgattttc ttatcagctc
    26101 ggaatcgaac gtgagaaata tgctgattgg catggaagaa agccgtaaat ggggaacccc
    26161 tgtcatgtta ggctattttc ccgatacatt tggaaatatg ggacagacgc ctcaattaat
    26221 gaaacaagct ggtatttcag cagcagcgtt tggccgtggt gtaaaaccaa ttggctttga
    26281 taatcaagtt ttggaagcag aaaactattc ttcccaatac tcagagatgt ggtggaaagg
    26341 ccctgatcaa acagcaatct ttggtctgct atttgccaat tggtatagca acgggaatga
    26401 gattccagta gaaaaagaag cagctcttgc cttttggaag caaaaattag cggatgcaga
    26461 acaatatgcc tctacgaacc acttattgat gatgaatggt gttgatcatc aaccggtaca
    26521 aaaagatata tcaaaagcaa tccatctcgc aaatgaactg tttccagatt acgagtttat
    26581 tcattctaat tttactgact atctggaagc agttcaaaaa gatgtgccag aagacttagg
    26641 ctcagtagaa ggagaattga caagtcaaga aacggatggc tggtatactt tagccaatac
    26701 agcatctgct cgggtttact taaaacaatg gaataccaag gtccagcgac agctagaaaa
    26761 tattacagaa ccacttgcga cgatggctta tgaagttagt ggaaactatc cccatgatca
    26821 attagattat gcttggaaga cattaatgca aaatcatcct cacgacagta tttgcggttg
    26881 ttcagtcgat tctgtccatc gggaaatgat acctcgtttt gaaaaagcag atgaagttgg
    26941 aaagtatctt gcacaagatt ccttagaaca gctgaccgca gcaatcgata cgaccggatt
    27001 cccaaaagac agctttccat ttgtcattgt aaatactgca ggaatggata aaactggtga
    27061 agcagaaata accatcgaat tagaaagaaa aagattcgct gaaggaatac ctgaacaact
    27121 atatcaagag ttagaaaatt tgcctaaacg taagtatcat gtagaaacaa aaagtggggc
    27181 cactatacca gctattttat ctgaagaaac tgtccaattt ggttatgatt tgccgaaaga
    27241 ccgtttccgt gtgccatata tggcaagaat gatcaaagtg actttaccat tagaaaacat
    27301 gccagcattt tcttgggaaa cattcgcgct tgtagaaggg gaagcgaaag cagaagaaaa
    27361 ggaaacaatg attcatcaga gtggacgaat catcgaaaac ggccctctac atttgacgat
    27421 tgaaaaaaat ggtaccatta caatggaaga tcgcaaaaac aaacgaaagt tgaataatct
    27481 gcatattttt gaagatatcg gcgatatagg aaatgagtat atctttaaac aacctttctg
    27541 tgatcagcca atcctatcca gtaacaaaga aaactctgaa gtaaaagtat tagtagatac
    27601 accggaaata gcaaaaataa gtattctaca ggaaatggaa atccctgttt ctgcagacga
    27661 gcgtttagaa aaagaacagc agatggttgt ggaatttcgt tatcgaaaag cagaacgatc
    27721 caaagaaaaa cgaatccttc aaataaaaac aatcatgaca atcagaaaag atagtaaaaa
    27781 aatcgacttt gaaacgactc tcgacaatca gatgaaagat catcgcttac gtgtcttgtt
    27841 tcctacaaag ttacatgtgg aacatcacga agcagatagt atttttgaag tggtgaagcg
    27901 cccaaaccat gtgtctaaaa gttgggaaaa ccccacgaat ccgcaacatc agcaagcatt
    27961 tgtcaatatt catgatgaag agtacggtgt aacagtcgga aactttggtt tgaatgaata
    28021 tgaagtaaca gaagacggac aaatcgcagt gacgctactt cgcagtgtgg gagaactagg
    28081 cgattgggga tattttccaa caccagaagc acagtgtcta ggtgagcatc ggttcaatta
    28141 cagcattgaa ctacatggac cagaagaaaa attctctact tatttgcatg catacgcagc
    28201 acagattcct ttttccactc aacaaatcaa acatcatgaa ggaacattga tttcaaaaca
    28261 acaatattta acgataaaaa gtgaaacgtt tgcaattaca gctttgaaac gcagcaagtt
    28321 tagtgataaa gtagtagtaa gaggtttcaa tatgtctagt catttagaaa aattggaaat
    28381 aactaaagac aatggaaaaa ctgtcatatt gaatctgctt gaagaaccaa cgaagcaagc
    28441 ggttgtccca ataatccaac cttatgagat tcggacaatc ggattcgagg aggaaaacga
    28501 atgtatggcg gaatagaagc aggcggaaca aaatttgtgt gtgcggtttc agatggtgga
    28561 gaaattttag aaaaattaag tatccctacc acaacaccag aagaaacatt ggatcaggta
    28621 tttgaatttt ttgatcgtta tgaattgaag ggaatcggga ttggctcatt cggcccgatt
    28681 ggtatcgaca aaacaaaaga taattacgga tacgttttgg caactcccaa aaaagggtgg
    28741 gcacaattcg attttcttgg cacaatcaag gaacgctaca atattcctgc tgcttggaca
    28801 acggatgtca atgctgctgc atatggggaa ttgaagcaag gagcagcaca aggaaaaaat
    28861 agttgtattt accttaccgt gggaacagga atcggtgcag gtgtcgtgat caatgaagaa
    28921 attttttcag ggatcgcaca tcctgaaatg ggacatattt gggtgaaacg ccatccagat
    28981 gaccattatg aaggtacttg tccttatcat aaagattgtt tagaaggatt agcagcagga
    29041 ccgtctattg aggcacgcac agggatcaaa gggcaagatc tgccgcaaga tcatcctgtt
    29101 tgggctattc aggcttatta tattgctcaa gcactgatca actatacgtt gacgttagca
    29161 cctgaaaaga ttattttagg cggtggggta atgaatcagg atcatctcct tcaaaaaatc
    29221 cgtcagcaat ttgttgaatt gatgggtggt tatatggaaa cacctcaagt aagtgaatat
    29281 atcgttcgtt ggggactgcc gaatgaaagt gggattatcg gtagtttgct gttagcagaa
    29341 cacgaacatc aaaagtaagc agacaaatta cacaaaaaga acagagtctt atcattatct
    29401 gctgataaga ctctgttctt ttttatttct attcccataa tccaggtaaa gctttaccga
    29461 ctattttttc ttgagtaaat ggatggatca tgtgcagttc taatgcatgg agcatcagtc
    29521 gttcagctgt tctattttgg tagagagggt ctccaacgat cggatgtccc ttatgagcta
    29581 aatgaactct gatctggtgt gtacgtccgg tttccaaaac acaatagact tgtgtttgtt
    29641 cagaaagtac tttgttgaca gtgacatgtg tcaaggcgct ctgaccattt ttatcatcta
    29701 cgaccctttt tctccgatca tggcgatctc gtccaatttt attggtgatg gtcatatctt
    29761 tggcaatttc tccccatacg atggcttgat atctccgata gatcattttt tgttccaaca
    29821 ttcttccaag tatcggcaag acaaatggat tttttgcaaa taaaacggca ccgcttgttt
    29881 ctttgtccaa gcggtggaca acgtaaggtc gttgctgttt agtgtcgaga taagcagcta
    29941 aatgattgag taaggtactg ttttctgtcg gttcatttgg atgagtcttc attcctgcag
    30001 gcttatccac tataatcaaa tgctcatctt catataaaac acggatgtgc ttcgcatctc
    30061 ctaattgaac ttcttgataa ttataatctg tttcttcgaa taacaatgtg atctggtcat
    30121 tgccctttac ttcatgatgg aacaaagcag gttgttgatt gatccaaacg tttttacgta
    30181 tacgcaaaaa gtgtcgaacc tttctaggaa ctaaccattc cttttcaagc aagtcgcgaa
    30241 ttgttgtttc aggatggttc ataggtaaag tgatcgtgat tttcacaagt gtactccttt
    30301 cagtgcaatt gcagactaat tgtaccattt ttaaaacata tttaagaaaa aacttacatt
    30361 tttctgttca ttcttatgtt actctacttg cactaacgta aaaaaacata ttgaactaca
    30421 acttaagcag gaagaaaaca ctctttcact atggtaaaat aagacgattg aatcaaatag
    30481 acaggagaag aagcaaatgg attttcaaag cattttagaa aagataaaag ctgctttgat
    30541 cagtttttgg cgttggatca gaccatatct cggacaattc catcgatggc gaaagcgcat
    30601 ctggaaaaaa tatcatgtga acaaattgat tttgctgatt ggtttgatct gtgtcttagt
    30661 gacaagtatc tacctcttta ttttagcaaa acaagcaaat gtcgaaacgt taaaatcagg
    30721 attaagccaa tcgacagtca tttatgataa gaaaaacgaa gaagctggca cactgtacgc
    30781 ccaaaaagga acatatgtag aattaaacgc gatttctccc tatatccaag atgcagtaat
    30841 ctcgacagaa gataggaatt tttacgagca tcacgggttt gatatcaaag ggattgcccg
    30901 tgcagcagtc cgaatggtct tgtctggcgg aacatcaggg ggcggaggaa gtacgatcac
    30961 tcagcagctt gccaaaaatg cgtatctgac attagaccaa acgtttgatc gaaaagcgaa
    31021 ggaattattt ttggcaatcg agatcgaaaa gaagtacagc aaagaagaaa tcttgaccat
    31081 gtatcttaac aatgcctatt ttggcaacgg ggtatggggt gtccaagacg cttccagaaa
    31141 gtattttgga gtagatgcaa cgaatgttac gctgtctgag gctgctactt tggcaggaat
    31201 gctgaaaggt cctggtattt ataatccgat cgatcaccca aaaaatgcga atgatcggaa
    31261 aaacacagta ctaagtgtaa tggaagaaaa cggaaaaatc acaaaagaac aagaacaagc
    31321 agaaagccag acagatatca gcgcgtatct taatgacaca tacgataatt cagattctgg
    31381 ttatcgttat ccttattatt ttgatgcagt gatcgatgaa gcagttaacg agtatggtct
    31441 tgatgaagaa gatgtcatga ataaaggcta taaaatctat acagctttag atcaggatta
    31501 tcaaaagcaa ttagaagcta cttatcaaaa cagtgcatta ttcccagcaa atgcttcaga
    31561 tggtgccatg gtccaatctg cttcagtagc tttagatccg aatacaggtg gtgtacaagc
    31621 actagtagga cgaagaggag atcatgtctt tagaggattc agctttgcta cacagatgcg
    31681 tcgttcacca ggatcaacga tcaaaccatt aagcgtatat acaccagcac tggaagctgg
    31741 atacaagcct tccagtatct tgaaagacga accgcaaagt tattacgatg cgcataattt
    31801 tgacgggaca taccaaggag aagtaccgat gtatcaagct gttgcacaaa gtttgaattt
    31861 gcctgctgta tggcttttgc atgagatcgg tttacaaaaa ggatatgata aagcagaaga
    31921 attcggcctg cctttagcaa aatctgataa gtattatggc ttagcccttg gtggactgga
    31981 aaaaggagta tctccattga tcatggcggg tgcttacagt gcatttgcca atgatggtca
    32041 gatgtatacg ccgcatctta tcacgaaaat cgttgattcg actggagcgg tgatcgtcga
    32101 taacacaaac aaaaaaccaa aacaggtcat atcaaaggaa acagccgatg aaatgaccag
    32161 catgcttctt ggtacatttt caaatggaac agcggctgct gcgaatcctg caggttatac
    32221 gatagcaggg aaaacaggaa ccacagaaac taatttcgat gccacaaaag caaatgacca
    32281 atggatgatc ggttacacgc cagacgtagt gatttcgaca tggatgggtt acgaagaatc
    32341 cagcaagctg cactatttgg aagggacaag tggaaatgtt gtcgggaaag tcttcaaatc
    32401 agcggcagaa ggcatccttc cgtatacttc aaaaacagga tttagtgtag cagatgccta
    32461 tgccacagga ggacaagtgg tagctgcaga tcaagttgga aacacaggaa attctaatgg
    32521 agagtctgga aattggcaag ataacttgaa tcaatatggt gaacaagcaa aagaagggct
    32581 gaaaaacttc ggcgatatgg tgaaagaagg cgttcaggga attggtgaag cggctaaaga
    32641 cctctggcgg aaatatcaag gagagtagcc cctttgaaaa cgaataaccc catgttacaa
    32701 tagagagtaa ctactaaaag aaaagagggc ataacatgtc aaacatctac gatagcgcga
    32761 atcaaatcga acgtgagatc cgtgaattac cagaattcaa agcgttgaaa gaagcgtacg
    32821 agaaagtaca agcaaacgaa gaagcacaca aactgttcaa agacttccaa gcgatgcaaa
    32881 tcgaattaca agaaaaacaa atgagtggac aagagttcag cgacgaagat gcaatgaaag
    32941 cacaagaaat ggctgtgaaa atccaatcag aagaagtaat caatgacttg atgcaaaaag
    33001 agcaaggctt cagtacaatc atcaatgact tgaaccgtat catcatgaca ccagttcgcg
    33061 acctttacag cgaataaaac tattttatga aacaacagag ggtgtgaaag agacgttcgg
    33121 ccttgagcga tgacaaaatt gcttcttatt gccgataggc tgtctcttga acaccattta
    33181 ccaagaggtc gtgagcctac cgtttaactc tgagttacaa ggaacaattt caaaaaacag
    33241 cttctcatgt ttgatgacta ttgtgacttg tgaccgagga gttggcagga gaacaccgtt
    33301 tattcagaaa taggagctac gacaaaagtc ttgtcatagc tcctattttt tgtcattcat
    33361 ttttcaagcg gtagaaatag cctttttgag ctaacagttt ttcgtaagta cctatttcaa
    33421 cgatttttcc ttcatcgatc acaacgattt tatctgcctc tttgatcgtt gaaagccgat
    33481 gagccacaat aaaagtagtg ggtgtttctg tcaggtaatt cagggcttgc tggatttttt
    33541 tctctgactg gttatctaaa gctgaggttg cttcatctag caaaatgatt tttggctgac
    33601 gtatcaacgc tcgtgcaatg gagatacatt gcttttggcc accagacagc ttgttgccat
    33661 gttcgcctac taaggtatcc agaccatcag gaagctggtc aatcagtgaa gaaagttgcg
    33721 cagcttcgat gacttcatct aaacgttctt ttgatacgtt tttcaagcca taagtgatgt
    33781 tctctttgat cgaagcggag aacaacaaag tggtttgagg aacaacggct aaataatttc
    33841 gcacacttcg catatccagt tcatccaaag gctgatcatc tagaaaaatt tttcctgaag
    33901 tcggctggat aaatccaatc aataagttaa ggagtgtaga ttttccagag ccagatggcc
    33961 caacaaaagc aattgtttct ccagctttca cctctagaga aaaatgatcg ataatcggtt
    34021 tgagtgagtc cggataaaga aaagaaacat cctcaaaacg aaaatttcca tccaaatgtt
    34081 ggattttttt cttaccgtga taagtttcta catcgccagc aatcaacagt tcgccaatag
    34141 aagtgataga ttccatgcct tttgaaatcg taggaatcag cgtgatcatt ccagaaacgg
    34201 aattgacgat cgtcgtgaaa tacgtctgat acatcacgac atcgccgggt tggatgcgcc
    34261 cttgtaaagc taatatccca gtgaaactca aacaaatcag ctgaaatatc tgaaaactag
    34321 cccagctgac tgatccgaaa acagattgca ggatatctaa gtggaatcct ttttcataga
    34381 tttgagtaaa atgcttattt aagcgagttg tttcgtgttt ttctaaccca tgagctcgag
    34441 caatcggtgc taattcgatc acttcgatca cttttgcaga agtctcttcc atttcttgcc
    34501 tgaagtctga gttggactgt ctgatccttt tacggaaaaa gagagtaacg aatgcggcga
    34561 gaggaacagt caataagaaa aacatgaaaa caacaggact tttataaagc gtgataccta
    34621 aagctacgaa taaattgaca gcgatattta atccgctgac aaatacttga gaggacaacg
    34681 tttggatagc ttctacatca cggatgatct ttgactggat tcgtccagat tgcaattctt
    34741 tttgataagg aatagatagt tcttggattt tcttgataag ggtcgctctt agtccagctt
    34801 ctacttgacg gatcgaagtg ctatggtatt ttacatgaaa ataattcgtc aatatatttt
    34861 gaccaatcag acaagccatc aaaaaagcgt tgaaataaat ggcctgcaac tgagaagaat
    34921 ctttcgatga agctgcattg attacattgg caatagcgat cggcattaac caagatggaa
    34981 gatgtttgat aataaaaaag agtcctgaca tggcaaaacg ccaataattt ccctgataaa
    35041 gatgcagcaa tgtctgaaaa gcatttgcat gatatttttg ataacttttc tgtattcgtt
    35101 cctccataat cttctcctta acaatcttgg taaataaact gcaagtgttc tattgcttca
    35161 ggaacataaa tctcaggagt agcttcaaga gtggcgtaca ttagaggacg ctcatatttg
    35221 atataatgca gtaccgggcg gaaatctaaa cagcccttgc caacaggtac catgcggatc
    35281 tttccatttt ccatgatata gtctttgaga tgaagcgctg taatataacc atgtaaattg
    35341 tccaaggcac ctcggatcac tttttcctga tcagcatgat tttctttatg catcaaattc
    35401 gcacaatcta aaatgatttt taaatttggt gaagctactt catcgattaa acgtttagct
    35461 aactgatagt tatagattgg atgattgatc cctgcttcaa cagcaacagt tacgccaaaa
    35521 ttttctgcat gagcgactaa ttcaatgata gaatttctgg cgatctgata agcttcttca
    35581 gtaaaatttt cttttgtgta accgacagag acactaccgg tttccgtagc aatcatcttg
    35641 gcttgatagg cagagcacag agcaatttgc tgtttgaaag ttgccaatgc ttgtgcacga
    35701 acttcttgat ttttgctgga taggttgata tagcatccta aaatggaaag ttcgatattg
    35761 tttttttgga agtattcacc aaaataggca gcactcccaa gtgtcatgtc agttaattta
    35821 agttgttcag gaaatgcttt ttgtggtgca aattggatat gggacaagtg aagctgtgat
    35881 actttttgaa cgatttcttc acgatttcga acatctaaat cgtgggcacg gatgcctaaa
    35941 tttaatggaa acatctcaaa ctcctttttg taaataatta gcaagaggca gacgggattc
    36001 ttttatcaat tcaacaatta ttcgggcaac tttatcagcg ccttctggac taaagtgggt
    36061 attgtctttt agtccttctg ggtaattttt acaagtatca ggcataagat gcaggtagaa
    36121 tttttttgtc tcttcttttg agaaggtctg gaacaattct tgtgatcttg agaacacatc
    36181 taaaagagga atatggtgtt tctcagcaaa tgcacgcatc gcttttggat agtctccaag
    36241 tatatctgga ttcaatgttc cgttttctaa gtaatctcgt cgcgtcacag atgtcagtaa
    36301 gaccatttgg acgttcgctt tttttgcgca ttcaaaaaat atctgcagat tttttaaata
    36361 gctaccgaag ggaagcgtac ctctttcttc ttggattttc tggtcgttat gtccaaattg
    36421 tacaaataag aaatcattcg gctgaaactg tgaagctaga cgggctaacc ttccttcctg
    36481 gataaatgat ttggtgctgc gtccattctt tgcttggtta ttgatctgga tctcgggtga
    36541 aaaataagca gagatttttt ctccccaacc tgtctcggga cgcttgtttt catctttttc
    36601 tgccgcagta gaatcaccgg caatatggat agtaggcatg ttatctcttc tttcataaag
    36661 gtttataggc aatgaagcag aacagcaaga gaagaagacg gagcaa
//
LOCUS       DAXLPY010000021        35141 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.021, whole genome shotgun sequence.
ACCESSION   DAXLPY010000021 DAXLPY010000000
VERSION     DAXLPY010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.021"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(106..801)
                     /locus_tag="ACF3UF_001172"
     CDS             complement(106..801)
                     /locus_tag="ACF3UF_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFD3671317.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(891..1991)
                     /gene="ychF"
                     /locus_tag="ACF3UF_001173"
     CDS             complement(891..1991)
                     /gene="ychF"
                     /locus_tag="ACF3UF_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFD3671318.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(2000..2191)
                     /locus_tag="ACF3UF_001174"
     CDS             complement(2000..2191)
                     /locus_tag="ACF3UF_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFD3671319.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(2212..3102)
                     /locus_tag="ACF3UF_001175"
     CDS             complement(2212..3102)
                     /locus_tag="ACF3UF_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFD3671320.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(3089..3856)
                     /locus_tag="ACF3UF_001176"
     CDS             complement(3089..3856)
                     /locus_tag="ACF3UF_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFD3671321.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(3868..4581)
                     /gene="rsmG"
                     /locus_tag="ACF3UF_001177"
     CDS             complement(3868..4581)
                     /gene="rsmG"
                     /locus_tag="ACF3UF_001177"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFD3671322.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(4813..6714)
                     /gene="mnmG"
                     /locus_tag="ACF3UF_001178"
     CDS             complement(4813..6714)
                     /gene="mnmG"
                     /locus_tag="ACF3UF_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFD3671323.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(6731..8128)
                     /gene="mnmE"
                     /locus_tag="ACF3UF_001179"
     CDS             complement(6731..8128)
                     /gene="mnmE"
                     /locus_tag="ACF3UF_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFD3671324.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            8427..8810
                     /locus_tag="ACF3UF_001180"
     CDS             8427..8810
                     /locus_tag="ACF3UF_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671325.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(8978..9736)
                     /gene="jag"
                     /locus_tag="ACF3UF_001181"
     CDS             complement(8978..9736)
                     /gene="jag"
                     /locus_tag="ACF3UF_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFD3671326.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(9754..10572)
                     /locus_tag="ACF3UF_001182"
     CDS             complement(9754..10572)
                     /locus_tag="ACF3UF_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFD3671327.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(10569..10925)
                     /gene="rnpA"
                     /locus_tag="ACF3UF_001183"
     CDS             complement(10569..10925)
                     /gene="rnpA"
                     /locus_tag="ACF3UF_001183"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFD3671328.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(11043..11177)
                     /gene="rpmH"
                     /locus_tag="ACF3UF_001184"
     CDS             complement(11043..11177)
                     /gene="rpmH"
                     /locus_tag="ACF3UF_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFD3671329.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            11700..13034
                     /gene="dnaA"
                     /locus_tag="ACF3UF_001185"
     CDS             11700..13034
                     /gene="dnaA"
                     /locus_tag="ACF3UF_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFD3671330.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            13232..14362
                     /gene="dnaN"
                     /locus_tag="ACF3UF_001186"
     CDS             13232..14362
                     /gene="dnaN"
                     /locus_tag="ACF3UF_001186"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFD3671331.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            14591..14833
                     /gene="yaaA"
                     /locus_tag="ACF3UF_001187"
     CDS             14591..14833
                     /gene="yaaA"
                     /locus_tag="ACF3UF_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFD3671332.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            14820..15944
                     /gene="recF"
                     /locus_tag="ACF3UF_001188"
     CDS             14820..15944
                     /gene="recF"
                     /locus_tag="ACF3UF_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFD3671333.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            15941..17887
                     /gene="gyrB"
                     /locus_tag="ACF3UF_001189"
     CDS             15941..17887
                     /gene="gyrB"
                     /locus_tag="ACF3UF_001189"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFD3671334.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            17907..20378
                     /gene="gyrA"
                     /locus_tag="ACF3UF_001190"
     CDS             17907..20378
                     /gene="gyrA"
                     /locus_tag="ACF3UF_001190"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFD3671335.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            20614..20913
                     /gene="rpsF"
                     /locus_tag="ACF3UF_001191"
     CDS             20614..20913
                     /gene="rpsF"
                     /locus_tag="ACF3UF_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFD3671336.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            20963..21475
                     /gene="ssb"
                     /locus_tag="ACF3UF_001192"
     CDS             20963..21475
                     /gene="ssb"
                     /locus_tag="ACF3UF_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFD3671337.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            21501..21737
                     /gene="rpsR"
                     /locus_tag="ACF3UF_001193"
     CDS             21501..21737
                     /gene="rpsR"
                     /locus_tag="ACF3UF_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFD3671338.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            21880..23853
                     /locus_tag="ACF3UF_001194"
     CDS             21880..23853
                     /locus_tag="ACF3UF_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFD3671339.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            23859..24311
                     /gene="rplI"
                     /locus_tag="ACF3UF_001195"
     CDS             23859..24311
                     /gene="rplI"
                     /locus_tag="ACF3UF_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFD3671340.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            24585..25952
                     /gene="dnaB"
                     /locus_tag="ACF3UF_001196"
     CDS             24585..25952
                     /gene="dnaB"
                     /locus_tag="ACF3UF_001196"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFD3671341.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            26732..28024
                     /locus_tag="ACF3UF_001197"
     CDS             26732..28024
                     /locus_tag="ACF3UF_001197"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFD3671342.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            28811..29674
                     /locus_tag="ACF3UF_001198"
     CDS             28811..29674
                     /locus_tag="ACF3UF_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3671343.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(29803..31425)
                     /locus_tag="ACF3UF_001199"
     CDS             complement(29803..31425)
                     /locus_tag="ACF3UF_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3671344.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            31674..32195
                     /locus_tag="ACF3UF_001200"
     CDS             31674..32195
                     /locus_tag="ACF3UF_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFD3671345.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSVLTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(32381..34111)
                     /gene="spxB"
                     /locus_tag="ACF3UF_001201"
     CDS             complement(32381..34111)
                     /gene="spxB"
                     /locus_tag="ACF3UF_001201"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFD3671346.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            34276..35094
                     /locus_tag="ACF3UF_001202"
     CDS             34276..35094
                     /locus_tag="ACF3UF_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFD3671347.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
BASE COUNT        10629 a         6819 c         6985 g        10708 t
ORIGIN      
        1 aagacttttg tcacagtccc ttactattat ttaactatgg ataaacaaaa tgaggttctt
       61 tactacccct agatatctag caaaatagct gatctttttg ctagtttatc ttcttgggac
      121 ggataaactt ccaataatcc cgtatttttt cttcaagtag taacggattg ctaaagcagt
      181 tgccccgata atgataacta ctactggatc taatactgga ttgataactg gtggcaatag
      241 tgttgtcgca gaaaacagta cgacccaaag aagtgtcgtt ccacctagga taagcaatgt
      301 cttacccatt cctggtttct tgcttcgatc tgctccggga tattcatatt gatagatgta
      361 tttgtacatc atataaaaga cccagccacc gattgcagaa cctagaacga gtgtagaaaa
      421 gccataagct ggcgttgttc cacgtgaaaa caatccggta atcgcaatca tgatacttaa
      481 tagaccaagc aacagcaacg tattatctaa ccacatcaat aaaggggtgg atgaattttt
      541 tacttctgct ggcttattga tgattgcttc cgttctttca gagactgtcc caaacaattg
      601 acgggctgtt cttccgcctt tttgttctgc aactaaagta ggcagaatgt catgaagggc
      661 ttttactttt tcttcttcag acaaattcgc tgcttctaaa gattttttca aatcaaaaat
      721 gtactgttga tttcttttgg ttaattttgt ttctaaacta ttgttttctt ttacgattgc
      781 tcgtaattgt tctggttcca ttatctaata gtcctcctta gccgttcctt ttctcaacgg
      841 tcgtcacaaa agacattcta ccatattcta cagctagttt gatagccctt ttacacatta
      901 aagcggaata acattacgtc gccgtcttgt acgacataat cttttccttc taatcgaaca
      961 cgtccagctt cttttgctgc atgcatgttt ccgtaatgat ccaagtcttc aaaagagaca
     1021 gtttctgcac ggataaatcc gcgttcgaaa tctgaatgga tgattcctgc tgcttgtggt
     1081 gctttgattc cttttttgaa tgtccaagca cgtacttctt gttccccagc agtaaagtaa
     1141 gtagctaagc ctaacaaatc ataagcagca cggatcaact gatccaaacc tgattcttcg
     1201 attcctaaag cttctaaaaa ttccgctttg tcttcttcat ctaattctgc gatttcttct
     1261 tctgcacgag cactgaccac gatcacttct gcattttctt ctgcagcaaa gttgcgcact
     1321 tcttgtacat aatgattcgc gtctgcatct gctacgtcat cttctgagac attggctaca
     1381 taaagaattg gttttgtcgt caataaaaat agtgatttaa cgattttttg ttcttcttca
     1441 gtaaattcga tcgttcgggc agattttcct tcttccagta caggtttgat tttatccagt
     1501 acagctagtt ctgccactgc atctttatct ttggttttag caacttttgc tacacgagta
     1561 tagcgtttgt tgatagattc taagtctgct aacactagtt ccaagttgat cgtatcaata
     1621 tcttctagtg gatcaacacg tccttctacg tgagtaatat tatcatcatc aaaacagcga
     1681 acaacgtgac aaatagcgtc tacttggcgg atatggctta agaattgatt tcccaaacct
     1741 tctcctttac ttgcgccttt tacgattcca gcaatatctg taaattcaaa agtcgtcgga
     1801 acagtttttt tcggatgtac aagttctgtt aagcgttgca aacgccagtc aggtacttct
     1861 accatcccta cgttggggtc gatcgtcgca aagggatagt ttgctgcttc tgctcctgct
     1921 tttgtgatcg cattaaacaa agttgatttt cctacgttgg gcaacccaac aattccagca
     1981 gtcaatgcca taaatttatt cactctttct ctgcattttt ttcaattact ttttttaatt
     2041 tcttttcaaa atctcgacgg gtcatcatga cgatatgtcc gcaattcata catctgattt
     2101 tgatatctgc gcccattcga atgacttccc agcgattcgt ctggcaagcg tgaggttttt
     2161 tcatttcaac gatatcgtgc aagtcgtaca taaaaatagc ctcctttttg tttattcttc
     2221 atcaaattga atattcaaga tatcaagaat tcgagtcaaa tctttttgag aaagatattc
     2281 aatctcgatc ttacctttcc catttttttc ttggatagct acacttgtac caaatttatc
     2341 catcaaacga tcttcgcttt ctcggatata atatggtttt tcctttgcta gccttgggat
     2401 ttttttcttt tcttttccat cattttgatt taactcagaa acaagctgtt ccagttggcg
     2461 gacagttaaa ttttcagtta ctgcacgatt ggctaatttc aagatcaatg ttttattttt
     2521 taaacctaac agcgtacggg cttgtcccat agataaacgc tgatcttgta ccatttcctt
     2581 gacaagatcc ggtaaagaaa gcaagcgcaa ataattggcg atataaggtc tgctctttcc
     2641 taaacgacta gctacttctg cttgtgttag tttcaggttt ttcatcagca tctcatatgc
     2701 ttctgcttct tctaacggat tcagatcttc tcgctgcaag ttttccagca ctgctacttg
     2761 catcatcgct tcttcgtcaa agtctctaac gatagcaggg atcgtttctt tttcagctag
     2821 tttggacgct cgaaaacgtc gctcccctgc aataatctca tatcctttta ctgcggaacg
     2881 gcgtacgatg atgggttgaa agacacctga ttgttcaata gaattagcta gttcctgcaa
     2941 agatacttct tcaaatgttt tacggggctg atacggattt ggtcgcagct cattcaatgg
     3001 tagctggaca acggtatcat cttttacatc caccgtctct aagttttcta aatcttgaaa
     3061 cagtgcatcg attcctcggc ctaatccttt acttttcttc acgacttacc acttcctttg
     3121 ccaatgcttg gtagacttca gctcctcgag aacgtggatc gtagtcgatg atcggttttc
     3181 catgactagg tgcttctgat aaacgaatat ttcttggaat gatcgtttcg taaacttttt
     3241 cgcggaagta tttacgtact tcttctacga cttcatttcc cagatttgtt cgtgcatcat
     3301 acattgtcag taagactccc tcgatctcta attctggatt aaagtgtttt tggactaaac
     3361 gaaccgtatt cagtaattgg cttaatcctt ccaatgcgta atactcacac tgaacaggta
     3421 tcaaaatcga atcacttgct gtaaatgaat tgattgtcag atggccaaga gaaggcgggc
     3481 aatcgatcaa aatataatca tactgactgc ttacttctgc taaagatcct tttaatcttg
     3541 attctcttgc catcattgac gtcaattcga tctctgctcc tgctaattgg agagtcgcag
     3601 gcacaatact caaattttcg tgttcagtga tcaaagttgc ctcatcaatt ggcaattcat
     3661 tgactagaac atcatagatg tctcttgtca catcaggttt tctgatcccg acaccactgg
     3721 tagcatttcc ttgtgcatcc atatccacta gcaatacttt tttgccaagg ctagcaagac
     3781 aagcacctag attcaccgtc gtcgttgttt tgccgacgcc acctttttgg ttcgcaacag
     3841 atattatttg tgccatctct tctcctccta tttgattggc tgcttattag gcagtccggg
     3901 ctttcttggg tatttctttg gggttggttt ctttttttga ataacgatga tatgccgttg
     3961 atcagagaca ttcggcaagg taaccgcctc ttctttgagg aatttaccac ctaataaagc
     4021 aatcgcttgt tttgcttctg tcaattcctc ttcacttttt gctgctttca atgcataaaa
     4081 atagccttct tgtttagcca agggcaaaca caattccgct aacacattca aacgagcaac
     4141 cgcacgagca gtgacaaggt caaatgatgc acgaaagtga ggattttgcc caaatgtttc
     4201 tgcccggtca tgatataagg aagcatcgat tcctaataat cgggttaact cagataagaa
     4261 ggttattcgt ttattcagag aatcaacgat cgttatctgc agttctggaa aggcaatttt
     4321 taaaggtatg ctaggaaacc ctgcccccga accaacatcg cataaagata aaggttgcgt
     4381 aaagtctact tcaaatgcta atgtaagtga atcgtaaaaa tgcttcagat atacgtcttt
     4441 ttcatccgta atagctgtaa ggttcatctt ttcgttccat tcgactaatg tccgataata
     4501 aatagcgaat tgattcattt gatgatcggt aagctctatc cctttttctg ccaaggattg
     4561 gcgaaattct tctggtatca taaatattcc tttcattgtg aaacagcaat tgtttcacag
     4621 attctctccc tactttaacg caaaatctct agacatgcaa tccttccata tggattctta
     4681 aaaatttgaa aagtaagaaa agccgataga ctttttcttt ctagtatgac tcataaaata
     4741 tacacagaag agagaactag ctttgagcaa tttctgcaaa aactagttct ctcttctatt
     4801 tattattacg tattacgctg gttcactgac tttcgcaatc ttcccttgtt cgatatagac
     4861 cattaggata cttaggtctg cagggtttac gccactgatt cggctagctt gggcaattgt
     4921 ttctggttgg attttctgca atttttgttt tgcttctgtt gctaatccgt tgattgctgc
     4981 gtagtcgatg ttttctggaa tctttttcgc ttccatgcgt tttaattttt ctactttttc
     5041 catggctttt ttgatgtagc cttcatattt gatttggatt tctacttgtt cgatttcttt
     5101 tcgtgtcaat tcttcatttt ctggaataaa ccgtagaagt tctgcataag taatctcagg
     5161 acgtcttaaa aagtcgcttg ctagtacacc atcttttaat ggtgccgcat taatcgttgc
     5221 taaaaagtct tggacttctt ctgttggttt gattcgtaca ttcatcaaac gtttgatttc
     5281 ttgttcaact gcttcttttt tcttcaaata attcttgtat tgatcttctt ttactaagcc
     5341 tacacggtga cccatttctg ttaatcgcaa atctgcatta tcatgacgta aaagcagacg
     5401 gtattcagca cgtgaagtca gcaaacgata aggttcgttc gttccttttg ttaccaaatc
     5461 atcgatcatg acaccgatgt aaccgtcact tcgtttgatc actaaaggtt cttttccctg
     5521 aactttcaaa gctgcattga taccggcaat cagcccttgt ccagccgctt cttcataacc
     5581 gcttgtacca tttgtttgtc cagctgtata aagattttca acgactttag tttctaatgt
     5641 cggacggagc tggtgtggct ctactacgtc atattcgata gcatatcctg tacgcatcat
     5701 ttctactttt tctaatccag caatagaatg aagcatgttg acttgaacat cctctggtaa
     5761 agaagtagat aaaccttgaa catagacttc ttccgtattt aagccttctg gttccaaaaa
     5821 taattgatga cgtggtttgt ctgcaaaacg cacgatctta tcttcgatgg atggacaata
     5881 gcgagcgcct accccttcaa cgatccctgt aaacattggg gcacgatgta agttgtctcg
     5941 aataatttgg tgagtcgtct cacctgtata ggtcagccag caagattcct gatctagttt
     6001 ataggcacta tctggtgtgc tgaagctaaa atgattcggc tctttgtcac caggctgctc
     6061 ttctgtaaca gaatagtcga tcgtacttga ttttactcga ggcggtgttc ctgttttgaa
     6121 ccgttcgata gcaaagccaa gttcttttag atgattcgct agtccaatag aaggttgaga
     6181 gttattcgga cctgatgaat atttcaattc accgataatg atttctccgc gaagtgctgt
     6241 tccggctgta ataacaactg ctttggcccg gtagctcgct cctgtggacg tcactactcc
     6301 atgacaaaca ccatcttcga cgatcagttc ttcgacgatt ccttgtctta gcgtcaaatt
     6361 tggttctttt tcgatcgtat gtttcatttc tgttgaataa gcatgtttgt ctgcttgtgc
     6421 tcgcaatgct cggacagctg ggccttttcc tgtgttcaac atacgcattt ggatataggt
     6481 tttatcgata ttcttaccca tttctccgcc taacgcatcg atttctcgaa cgacaacgcc
     6541 tttagctggt ccgcctacag aaggattaca tggcatgaat gctaccatgt ccaaatttat
     6601 tgtcagtaat aatgtttttg atcccatacg tgcagcagca agtgcagctt ctgaaccggc
     6661 gtgtcctgcg ccaacaacga tcacgtcata cgcatctgct tcataatgtt ccaatcgttt
     6721 gttcctcctt ttattttcct aaacaaaatt gactgaataa ttgagtgatt agctcatctt
     6781 gtacactgtc gccgacaact tctcctagat agtcccagca acgcgtcata tctatttgaa
     6841 cgagatccac aggcattcct gaatcaatac ctgcaatgac ttcttcaagt gagagggaag
     6901 ctttttctaa caacgcgata tggcgggtat tagaaacata agtagcgtct ctttctcctg
     6961 tttctccgct gaagaataaa tcagaaatag ctgattccaa acgatctagt ccgtcgtttt
     7021 tagctacgga aattgaaaaa actggttcat tttcgatcaa tttcttcaat ttttcttgtt
     7081 ccagctgtgc tggcaaatct gttttattta gaagaatgat ccgtttcaat ccacttgtcg
     7141 cttccaataa ttgttcatct tctgctgtca gtggttcgct ttggtttaga acaagtaaga
     7201 tcaagtctgc ttctgctaat gcttttcggc ttctttcgac cccgatccgt tccaccacat
     7261 cttctgtttc ccgaattcca gctgtatcga ttagcttgag cggtaccccc cgaacattga
     7321 catactcttc gattacatct cgagtcgttc ctgcaatatc cgtaacgatt gctttttctt
     7381 ctcttaacaa atggtttaac aaacttgatt tgccgacatt tggccggccg atgattgccg
     7441 tacttaaccc ttcccgcaga accttccctt gcttggatgt agcaagtagc gcttggattc
     7501 tttgttggat catctgcgct ttttcaagca ataacttcgt agtcaattct tcgacatcat
     7561 catattctgg ataatcaata tttacttcta cttgtgctaa tgtctctaaa atctcttgtc
     7621 tcaatgagcg gatcaaagca gacagattgc cgtctaactg attaagagct agtcccattg
     7681 ctttgtctgt ttttgcccga atcaaatcca tcacagcttc tgcctgtgaa aggtcaacac
     7741 gaccattcaa gaatgctcgt tttgtgaatt cgcctggctc agctaatctt gcaccttctc
     7801 ttaacaatag ctgcaaaatt tgattgacta caacgatccc accgtgacaa ttgatttcta
     7861 ctacatcttc ccgcgtaaat gtctttggtg ctctcatcac ggagaccatg acttcatcga
     7921 caagctgatt gctcttggga tcaacgatat gtccataatg gatcgtatga cttggtactt
     7981 ctgataatcg tttgtttcca gattgataaa ctttatctgc tagttgcaca gcttgatcgc
     8041 cacttaaacg aacgatactg attgcacctt ctccaggtgg ggtagaaatt gccgcaatcg
     8101 tatcaaattc taaagtaatt tcagccattt tttcacttcc tttttcattt tgcgcacaaa
     8161 aaaagtgccc actccaccct ttatgcacaa taaacggtga acttcgcact ttgactgctt
     8221 gttcttgatt aaattctggt catagattat cacacttgct ataaggaatc aagtgtttaa
     8281 aacaattaga tgaagttgag cctgttctgc ttccattacc ttatatttaa ttgtccttgg
     8341 atgtctcttt gcgttctttg gtttattcga agagaagata ctgtataaac aaggctttat
     8401 ctttcttaaa aaaaacggta cactaaatgg tagcgctatc taaactatac acttttgaaa
     8461 ggagaaaata tgtgagcccg ttcagatctg ctgcattgga agaagaaagt gaccctcgga
     8521 tcaacgatgt cgttttatct acagggaata tcaaccagaa atatatcgtc cgcgatatcg
     8581 tttttgttgt ggaatgctta gaagctgatt tgtttgaccc atcttttccc aaagatgacc
     8641 ttttcttaac aacgaagagg aaattaaaga cgaaggtact tgaatatggt gcgaatgcag
     8701 taatcaactg tcattttgag tatcagcaaa aaaaacgcga cggaaagtat tttctggaac
     8761 tttttgctta tggaacagtg atccaattta tccaaacaac gattggttaa atgaaacaga
     8821 caaaaaaagc ggatcaaaac tgaagacagt ttcgatccgc ttttttctat caaagttagt
     8881 gactacttca tcgtatactc tgataagaat gatttctagt aaaatatact tggtttgaaa
     8941 aactttgtca acgtgattta ttcaaaaagt aatggaatca ataatatttt ttagcaggtt
     9001 ctactactaa ataacgataa ggttcctcac cttccgaatg tgtttttaca tgttcatctt
     9061 tgcttaatgc agcatggatt tgtttacgtt caaatgcagg cattggttct aagaaaacag
     9121 gctgccctgt ccgttttact ttttcagccg tgcgatcagc taaacgctga atgatctctt
     9181 ggcgcttttc acggtaattg cctacattga ctactacaga cagcttattt cttgctaaac
     9241 gatggatgaa gacttgtgcc agatattgca atgcattcag tgtttttcca tgtttcccaa
     9301 tcagtatgcc ttgcttttgt gtttctaaat ggaaaacaac catattattt gattctcttt
     9361 ccattttgac aagagctgga gcatcaagct gttttgaaat ttcagtaaga taaactgcca
     9421 attccgttaa agctgcttca tcacctagct cacttacttc ttctgttttt tcttcaagaa
     9481 tcgtttcgtt gactacctcg atctcagctg ttggttcttc ttccaaaatt tcttctacag
     9541 tctgttctac tgtttcagaa actttttcgc tgatacttgg ctggatcgaa agccgtgcat
     9601 tctttcgacc cattcctagg aaaccttttt ttccttcttc cagtatttcg atttcgactt
     9661 ggtctttggc caaacccaaa tcagccagac ctagttggac agcttcgtct attgttgcag
     9721 cttcataaat cggcattagc attacctccc ctattatttc cgttttttct taggattcat
     9781 tgctttctta agagcacgtt ctctttcgcg gattctccgt gcttcttctt cacgctcttt
     9841 tcgaattttg aaagggttgt tgatcagcag cgtttgtaca acttggaagg cattggaaac
     9901 tacccagtat aatgaaagac cgctggctaa attgacaccc atcactaaaa tcattacagg
     9961 catcacgaaa ttcatgatct tcattgatgc attcgattca atttgactca tgctagataa
    10021 atacgtactt gcaaaagtaa agattgctgc taaaatcggc aaaataaatg ttggatccgc
    10081 gttccctaag ttcaaccata agaaatgccc ttgtttcaac tctggtacac gtgaaataga
    10141 ttgccataac gccatcaaga ttggcatttg tactaataaa ggaagacaac cagcatatgg
    10201 attgacgcca ttttctgcat ataaacgctg ctgctcttct cttaacttac tttgtgtttc
    10261 cggatctctt gaactatatt gttgctgcag tgcttttaat ttcggttgta attcttgcgt
    10321 tttacgcatg ctctttgttt ggaaatgcat caacggcaat aggatcacgc ggatgatcag
    10381 tgtaaataaa atgatcccta tccctgcatt accaaatgac aacgccttga tcgcctcagc
    10441 aaagtaataa acaatataac gatcccaaat tcctgtactc tgtgcgctga cttccccagt
    10501 tccgcaaccg gataagacga tgaccaaact aacgataccg gccatcaaaa gtaaacgttt
    10561 gtatttcttc acttactctt ttcctctctg tcgattattt ttgcaagttt taagacgtgg
    10621 actaaattgg agcgaacctc atcataagtc aaccccttca cacttggtct agcaatcaca
    10681 ataaaatcca actccggatc aatttcttct tttatagaat aaactgctgc tcggattttt
    10741 cgtttgactt cattgcggtt taccgcgttg ccgacctttt ttcctacaga taaaccaact
    10801 cgaaaatgag gctgtcccgg tttttccaaa cggtaaacga cgaatttgcg gttagcaaaa
    10861 gaatctcccg tatggaacac ggcttgaaac tctcgttctt tttttactcg atacgctttt
    10921 ctcattagtt ttctttcctt ttctatctct cacttacgct cataatcata ccataattac
    10981 gattgtcctt tcatcatttc cctaaaaaag agtataaaaa aaaccactga aaccccagtg
    11041 gcctaagctg aaagaacttt tcttcctttg cgacgacggc tagctaacac acgacgtcca
    11101 tttttagtac tcatacgttt acggaatccg tgaacttttt gacgtttacg tttatttggt
    11161 tggtatgttc ttttcatata ttccacctcc aaaatgttct tatctatttt ataaacacag
    11221 acatactttg atagtataac gacaaagtag tgattttgtc aatataaaat agaagatcga
    11281 ttgttaaaac ttatccacaa gattattttt ttctatggga atcctatgtg gaaaaagtta
    11341 tgcacaggga ttatccacag ataataaaag gctggtttta cacagaaaac acacgtgtaa
    11401 aaaaagtaat ccacaatcag gcgatttcct gtgtattccg tctcctaact attggtatat
    11461 ctgtattttt tatccacaga cgcaagagga aatctattgg tttttacgag ttttccacct
    11521 gtgcattagt ggtgtggaaa actttttttg acaactgtgt ttttctcttt tttctttttg
    11581 tcgattgtgt ggataattgt aattaaaaaa tttttttctt cggtttctgt ggaaaactat
    11641 tgaaaaaaat gctaaattag tactagttat tcacttttta atgaaggagg aggccttata
    11701 tggtatccct cgatgcttta tggaatgaat taaaagcaac ataccaaaag gatttatcgc
    11761 ctgctagcta taatacatgg atcgaaacag cgaaccctcg aacccttgat caaaaccagc
    11821 tcgttgttga ggttcctagc aagattcata aagaatattg ggaaaaaaac ctggcgacaa
    11881 aaatcgttga agtcggttat atgttatcag gaaatgagat tatccctcgc tttattactg
    11941 gcgaagaagc agagcaagaa gaagttatag aagaaaaaaa tccaaaagtt gtggcaccta
    12001 gtccgctaaa aaaagccatg ctgaacccta aatatacctt tgatacgttt gtcattggta
    12061 aaggaaacca gatggctcat gcagcagcgc tcgttgtagc agaagatcca ggttctattt
    12121 ataacccgct cttcttttat ggaggcgtgg gacttggtaa gactcacttg atgcatgcaa
    12181 ttggtcatca aatgctgcaa agtcagccta atgccaaagt aaaatatgta agcagtgaaa
    12241 cttttgctaa tgatttcatc aattcgatcc aaaacaaaac agcagaagag ttccgtcaag
    12301 aatatcgaaa tgttgattta ctgctagtgg atgacattca attttttgca gaaaaagaag
    12361 ctacgcaaga agagtttttc catactttca atgccttgta caatgaaggg aaacaaatcg
    12421 tactaaccag tgatcggttg ccaaacgaga ttccgaaact gcaagaacgc cttgtttctc
    12481 gctttgcatg ggggctgtct gttgatatta caccgccgga tcttgaaaca agaacagcga
    12541 ttttacgtaa aaaagcggcg gctgaacgtc tagagatccc agatgacaca ctaagctaca
    12601 tcgcaggaca aattgattct aacattcgtg aattagaagg tgcgcttgtt cgagtgcaag
    12661 cttttgctgc gatgaatagt gaagatattt cgactagtct agctgcagac gcactgaaaa
    12721 cgttaaaatc aggaaaagga catcctcaat tgtcaatcct gcagatccaa gaagaagtgg
    12781 caaagtatta tcacatccaa ttgaaagatc tcaaaggaaa gaaacgcgtc aaatctattg
    12841 ttgttcctag acaaatcgct atgtatttgg cacgtgagct cacagataat tctttaccga
    12901 aaatcggagc tgaattcggt ggcaaggatc atacaacggt tatccatgct catgaaaaaa
    12961 tccagcagct gatggattct agtgtcagta tgcaaaatga agtatcagaa atcaaaaact
    13021 ttttactaaa ttaatttgtc gattctatca actgaaaata gcatgtggat aaaagaaaaa
    13081 aacgttcaaa agttatacac actttttcca cagctgtttt ttcgtttctc tcttacgttt
    13141 tttgagtttt ccacagaatc aacatgccct attactttta ttattctttt taactaataa
    13201 taaataaaca aacattcaaa ggagatacat catgaaagtt actttaaacc gagctagctt
    13261 tatgcaggaa ttgcaaactg ttcaacgagc tatttcaagc aaaaccacga tccctatttt
    13321 gacaggtgta aaaatcacac tgacacaaga aggtttgact ttgacgggga gcaacgctga
    13381 tatatcaatt gaaacttttt tgtctgttga aaacgaaaaa gcaaatatgc aaatcgaatc
    13441 tactggttcc attgttttac aagcacgttt ctttagcgaa atcattcgga gacttcctga
    13501 agaaacattt actttagaag ttttagaaaa taaacaagta gcgatcactt ctggaaaagc
    13561 gaattttatc gtaaatggat tagatgcaga taactatcct catcttcctg ttgtcgaaag
    13621 ccataaccag atgaaattac ctgtacacgt attgactaaa ctaatcaacg aaacagtttt
    13681 tgctgtctca caacatgaga gtcgtccaat cttgacaggt gtgcatttca ttttatctga
    13741 taattcttta ttagctgtag ctactgattc tcaccgtcta agtcaacgcg tgattccagt
    13801 agaacaagcg gctgatcatt ttgatattgt tattcctgga aaaagtttga tcgaattatc
    13861 tcgctcatta acaaatgaag aagaaatcgt cgaaatcagc attatggaaa accaagtgtt
    13921 gttcaaaaca gaaacgatgt atttctattc ccgtttgcta gaaggaaact atccagatac
    13981 caatcgtttg attccttcaa gttttaatac agaggttgaa ttttctgttc ctagcttttt
    14041 agcggcgatc gaacgggctt ctttactttc tcatgaaggc cgtaacaaca tcgttcgttt
    14101 atctattcgt ccagatgcgg ttgttttata cggaaattcg ccagaaatcg ggaaagtaga
    14161 agaaagcttg agttatacag caagcagtgg cgatccatta gatatttctt tcaatccgga
    14221 ttatatgaaa gcagcgttgc gtgcatttgg agatatgagc atcaaagtga aatttatctc
    14281 tgctattcgt ccatttacat tggaaccaac ggaagatggc gttcaattta ttcagctgat
    14341 tactcctgta cgtacaaatt aacaatgatt ttcaatgttc ttgaaaattt aattgaaaag
    14401 aaatagaaaa aataaaattt taaacagaag gccctaaaat ctcttttaag gctttctgtt
    14461 tatttttgtt taaatcacct tttttagatt aaatcgtctt atatggaaaa atatatggat
    14521 aaatttgttt tattgcgaaa aaaaaggtat aatagagtat acttttaata atgaaaatga
    14581 gggatgggca ttgaaacaac aagtcattct aaatacggaa ttcatgacgt tgggccaaat
    14641 gttgaaagaa gtcacagtta tcggtagtgg cggacaagca aaatggtatt tggcagaaaa
    14701 cactgtgtta gtcgatggcg aaccagaaaa tcgtcgtgga cgcaaacttt atcccggcat
    14761 gatggttgaa gttccagaag taggaacttt ttttatggta aaaaaaggaa acgacgataa
    14821 tgaggctgaa taagctgtat ttaaaaaatt atcgaaatta cgaagagctg aacatcgaat
    14881 tttccaagaa cctcgtcatc tttttaggag aaaatgcgca aggaaaaacg aatcttttgg
    14941 aaagtatcta cgtattagct atgacgcgaa gtcatcggac aagtagtgag caggaattga
    15001 ttggctggac tgacgatcag gcgatgattc aaggagagat cacaaaaggt tcatccactc
    15061 ttccattaga aatcttatta tctaaaaaag gccgaaaaac caagatcaac catatcgaac
    15121 agaaaaagtt aagtacttac gtgggacaaa tgaatgtcat tttatttgca ccagaagatc
    15181 tttctttagt aaaaggcagc ccgcagatca ggcggaagtt tttagatatg gaattaggcc
    15241 agatcaatcc aatctatctt tatgatcttg tccaatacca agcaattttg aaacaaagaa
    15301 accagtactt gaagcaattg aatgaaaaaa aacaaactga tttgctttat ttggatattt
    15361 tgtccgaaca actagcagcg tttggcagca aagtattgaa agcaagagca cagttcgtca
    15421 agcgattgga gttttgggct aattctttgc atcagcaaat cacccatcaa aaagagcagc
    15481 tggaaatcga gtatctcacc gcagtcgatt ctttagaaac acatacgcaa gagcaaatcc
    15541 aagaacaatt tctcgcactt ttgaaccaaa ataaaaagaa agaccttttt cggggaacaa
    15601 cgacagttgg tcctcatcgt gacgatcttt ccttttttat taatcagaaa aatgtgcaga
    15661 cttatggatc gcaaggacag caaagaacaa ctgcactaag tgtcaaatta gcagaaatcg
    15721 atttgattaa agaagagaca ggggaatatc caatcctttt gttagatgat gtgatgagcg
    15781 agctggatga taatcgtcaa ctccatctgc tagaaacaat cgaaggaaaa gttcaaacgt
    15841 tcttaacaac aacgacactt gaccatgtaa aaaataaaat gactgttgaa cctgagattt
    15901 tttatgttca acaagggaaa ctaaaaggag aagaaactga atgacagaag aaagaagttt
    15961 agtagaacgc gctaaagagt atgatgccag tcagattcaa gtacttgaag gacttgaagc
    16021 cgttcgtaaa cgacctggca tgtatatcgg ttcgactagt tctgagggtc tgcatcacct
    16081 tgtttgggaa attgtcgata attcgatcga tgaagtatta gcaggttttg caacgaaaat
    16141 ccatgtgatt attgaaaaag acaacagtat caccgttatt gacgacggtc gggggatacc
    16201 tgtagatatc caggcaaaaa ctggacgtcc tgcagttgaa acggtcttta ctgttttaca
    16261 tgctggagga aaattcggcg gtggtgggta caaagtttct ggtggacttc acggagtagg
    16321 atcttctgtt gtaaacgcgc tttctacaca gcttgatgtc aaagtataca aagaaggaaa
    16381 tgtgtactat caagaatatc gtcgtggagc tgtagtggac gacttaaaga ttatcgaaca
    16441 aacggatcgc catggaacaa cggttcactt tacgccagac cctgaaattt ttacagagac
    16501 aactgagttt gatttttcaa aattggctac ccggatccgt gaacttgctt tcttgaaccg
    16561 cgggatgcgt atatcgattg aagacaaacg agaagaagaa ccagtcatca atgaatacca
    16621 ttatgacggc gggatcaaaa gttatgtcga atacttgaat gcaaacaaaa ccgtgatttt
    16681 tccagaacct gtatatttgg aaggtgaaca gcaagatatc gcagttgaag tctctatgca
    16741 atatacagac ggctaccatt ccaatatcat gagttttgcc aacaatatcc atacgtatga
    16801 aggtggaaca catgaatcag gattcaagac tgctttaact cgtgtgataa atgattatgc
    16861 ccgaaaacaa aagctgatga aagaaaatga cgacaacttg accggtgaag acgtgcgaga
    16921 aggattgaca gctgttattt ctatcaagca tcctgaccct caattcgaag gacaaacaaa
    16981 aacaaaattg ggcaattccg aagtacggac agtcactgat cggttattta gcgaacattt
    17041 catgaaattc ttgctggaaa acccaagtgt gggccggcaa attgttgaaa aaggattact
    17101 agcttccaga gctcgtctag cagcgaaacg tgcgcgtgaa gtaacgagac gtaaaggtgc
    17161 tttagagatt agtaatctgc caggaaaatt agcggactgc tctagcaacg atcctgaaaa
    17221 atgcgaattg ttcatcgtcg aaggagattc ggccggcgga tcagctaagc aaggtcgtaa
    17281 tcgagagttt caagccatct tgcctattcg tgggaaaatc ttgaatgttg aaaaagcaag
    17341 catggacaag atcttggcaa atgaagagat ccggtcttta tttactgcta tgggtacagg
    17401 gtttggagaa gattttgatg tatcgaaagc tcgctaccac aaattagtta tcatgactga
    17461 tgccgatgtc gacggcgcgc atatccgtac attgctgctg actctttttt atcgttacat
    17521 gcgtcctatt gttgaagctg gatacgtcta tattgctcag ccacctttat acggggtaaa
    17581 acaagggaag aatattacgt atgtacaacc aggaaaaaat gcagaagaag agttgaaaca
    17641 agtcgttgct tcacttcctg cctcaccaaa accaagcgtt cagcgttata aaggacttgg
    17701 agaaatggat gatcatcaac tatgggaaac aactatggac ccaagcaatc ggatgatggc
    17761 ccgcgtcagt gtggacgatg ctattgcagc agatcagata tttgaaatgt tgatggggga
    17821 tcgagtagaa ccccgtcgtg cattcatcga ggaaaatgca cactatgtga agaacttaga
    17881 tatttaatca tgaaggagga aaaagaatga gtgaagaaat cagagaaaac atccatgatg
    17941 tcaatctaac cagcgaaatg aaagactcct tcatcgatta tgcgatgagt gttattgtcg
    18001 cacgtgcact tcctgatgtc agagatggtc tgaaacccgt tcatcgccgt attttatacg
    18061 gcatgaacga attaggtgta acaccggata aagcccataa aaaatctgcc agaatcgtcg
    18121 gagatgtcat gggtaaatac catcctcatg gagacattgc gatctatgag tcaatggtac
    18181 ggatggcaca gccattcagc taccgttata tgctagtgga tggtcatgga aactttggtt
    18241 ctgttgacgg tgacggtgcc gccgctatgc gttataccga agcacggatg agcaaaatcg
    18301 ctacagaaat gctgcgtgat atcaataaga acactgttga tttccaaagc aactatgatg
    18361 atacagaaaa agaaccagtt gtactacctg ctcgcttccc gaatctttta gtgaacggaa
    18421 caacggggat cgccgtaggt atggccacga atatcccacc tcataacttg tctgaggtag
    18481 tagcggctat cgatttgctg atggataatc ctgatgtgac gaccaatgaa ttgatggaag
    18541 tattacctgg accagatttt ccaacaggtg gtttggttat ggggaaatca ggaatccgaa
    18601 gagcgtatga aacaggtaag ggttctatta ccgtacgtgc aaaagttgag attactgaga
    18661 tgccaaatgg taaagaacgg atcatcgtga cagaattgcc ttatatggtc aataaagcaa
    18721 aattgatcga acggatttct gaactgcaca gagacaagcg tatcgaaggg atcacagatt
    18781 tgcgggacga atcttcccgt gaaggtatgc ggatcgtcat tgacatccgt cgtgacgcca
    18841 gcgcatccgt tatcttgaat aacttatata aattgacatc cttgcaaaat tcatttggat
    18901 tcaatatgtt ggcgatcgaa aaaggtgtgc cgaaagtttt gagcttgaaa caaatccttg
    18961 aaaactatat cgaacatcaa cgcgaagtca tcacacgacg gacggtcttt gaaaaagaaa
    19021 aagcagaagc aagagcacac atcttagaag gtttgcgtat tgctttggat catatcgatg
    19081 aaatcattgc gattatccgc gggtctaaat cagatgacga ggcaaaagca acaatgatcg
    19141 aacggttcga tttatccgat cgccagtctc aagctatttt agatatgcgt ttacgccgat
    19201 tgaccggttt ggaacgggaa aaaatcgaaa atgaatacca agaactctta aaactgattg
    19261 aagatttaac tgacattctg gcaagaccag aacgtgttac agaaatcatc aagaatgaat
    19321 tagcagactt gaatcaacga tttggtgata aacgacgcac agaattacta gtcggtgagg
    19381 tcttaagtct ggaagatgaa gatttaatcg aagaagaaga aatcgttatt acattgacaa
    19441 acaatggtta catcaaacgt ttggcaaata atgaattcag agctcaacga aggggtggac
    19501 gtggtgtcca aggaatgggt atccacaatg acgacttcgt caaaaatctg gtttcttgtt
    19561 ctacccatga tacattgtta ttctttacga ataacggaaa agtgtatcgg gcaaaaggat
    19621 acgaaattcc agaatacggg cgtacagcca aaggaatccc aatcatcaat ttactaggta
    19681 tcgattcgag tgaaagcatc caggcaatca ttgcggtgac gggagaagca gaagaaggcc
    19741 actatctctt ctttacgacg cgtcaaggta cagtaaaacg tacttctgtc actgcttttg
    19801 ctaacatccg aagtaatggt ctgatcgcaa ttggtttgaa agaagacgat gagctcgtca
    19861 atgtgctact gacagatggt caatctaata tcattattgg aacacataac ggctactctg
    19921 tcactttcaa agaagaagca gtccgcgata tgggacgtac agcttccggg gtcagaggga
    19981 tacgcctgcg tgaggaagat tatgtcgttg gggcagcctt aatgaaggaa aatcaagaag
    20041 tattagtgat cacagaaaaa ggttacggaa aacggacaaa agtatcggaa tatccagtga
    20101 aaggccgcgg aggtaaaggg atcaaaacgg cgaacatcac tgaaaaaaat ggtccactag
    20161 ctggattgac cactgtttct ggagatgaag acatcatgct gattacagat aaaggtgtca
    20221 ttatccgttt caacgtatcg actgtttctc aaactggacg ttcaacatta ggcgtacgtt
    20281 tgatgaagat ggaagctgat acgaaagttg tcacgatggc agcagtcgaa ccagaagctg
    20341 cagaacaaac agttgaagaa caaggatcag aagaataacc atcaagacta agtgtgtaag
    20401 ctagcaagaa taaccgatta aaaaatctgg ttattcctgc tggctttttt gattagttga
    20461 atttctctta aaatattcga aactgttcat tctgtattgc ttttgaccaa aatagagtgt
    20521 ataattagag cttgtgagta gtctaattaa ttagataact ctccttgctc ttaggaacct
    20581 aagagccgaa agtccacagg gaggtgaata tcaatggaaa acacgaaata tgaaatcatg
    20641 tacattattc gtccaaacat tgatgaagaa gcaaaaactg ctttaatcga acgtttcgat
    20701 gcaatcttga aagataacgg agcagaagtt atcgaatcaa aagattggga aaaacgccgt
    20761 ttcgcttatg aaatgaacgg ttaccgtgaa ggtatctatc acatcgttaa agtatcttct
    20821 ccatcatcag caaatgctgt caatgaattt gaccgtcttg ctaaaatcaa cgacgatatc
    20881 attcgtcaca tgattgttaa agaagaagct taattgttgt ttcatgtgaa acaatagaaa
    20941 acgatgagag gagatgacta ttttgattaa taatgttgta ttagttggac gtctgacgaa
    21001 agatccagat ttgcgttaca cagcaagtgg tacggcagtc gcaacattta ctttggctgt
    21061 gaatcgtaat tttacaaacc aaagcggcaa tcgcgaggct gattttatca actgtgtgat
    21121 ttggcgcaaa tcagcagaaa ctttagcaaa ctatgctcgt aaaggaacac ttttaggtgt
    21181 tactggacgt atccaaactc gttcttatga taatcagcaa ggacaacgtg tatacgtgac
    21241 agaagtagta gctgacaact tccaattgct ggaaagtcgt tctgcatctg aaaatcgcca
    21301 acaaagcggc ggattccaaa gttctggtca atcagctggc ggatttggcg gaaacaataa
    21361 ctctaatcaa acatctcaat catccaacgg tatgcctgat ttcgaccgtg atacttctga
    21421 cccattcggc tcaagttcaa cgatcgacat ttcagacgat gatttaccat tctaaacgaa
    21481 tttgatagga gggaaataga atggcacaac aaagaagagg cggacgtaaa cgtcgtaaag
    21541 tagactacat tgctgctaac catattgaat atatcgatta taaagatatc gaattactaa
    21601 aaagatttat ttcagaacgc ggtaaaatct tgccacgtcg tgtaactggt acaggcgcta
    21661 aaaaccaacg taaaattact gttgcaatca aacgcgctcg tatcatgggc ttgctacctt
    21721 tcgttagcga agactaataa atcctaggaa ttgaatgact gatccttttg atcagctatt
    21781 caattccttt ttttctgtaa aaataacctc tattcgttta gtcgctcgaa tgacgaaagt
    21841 tatggtaaaa tcaaattagt catatatggg aggaaaatta tggaaaataa aaacaatcat
    21901 ttatccccga aacctctctt ccttatcctg tttatattaa tcgaagtatt ggtagtctta
    21961 attttaccat ttcgttttgt tagcgcttcg gtcattctat tgatgaattt atggggtgtt
    22021 cgctattggt tgaaaatgaa acgttggctt attttaaata aacgtgaaaa aatccagcag
    22081 gcttcgactg tagctgaaac caatctagct tatgtctcag aagtcatgcc tgtaggagtg
    22141 attgcttatc agccatcaag ccaaaaaatc gaatggctca atccattagc attgaaaatc
    22201 aaagatcaaa gtggattaac agaggaagaa ttgctagata ctttttttac tgcaaaagaa
    22261 aaaaagaaaa accaagtcta tctagcagat aaaacatttc agtttgatat ggatacagta
    22321 aagggtgttg tttattttaa tgatattacc caaaaccagt tgttaaaact ccatcagacg
    22381 aacagtcagc cggtgattgg tattttatct attgataact atgcagatgc cattgataaa
    22441 ttagatgaca aagagatttc ttatttgaac tctttcgtca ctacactagt ttctgactgg
    22501 atgaatgaat accatgtctt tttcaaaaga atcaacgcag aacggttttt cttcgtagca
    22561 cagatgatcg atctgaaaaa gatgatggat aaaaaatttg atttgctgga tcgctttcga
    22621 gcagaagctg aaaaacagag ctcgcctatc acccttagta tggggattgc ttatggctca
    22681 agaaccctcg atgaaatcgg tggagaagct cagaataatt tagatgttgc tttagtccgt
    22741 ggaggcgacc aagttgtcgt gaaagaggta aaagaaggag caaaacctgt ttattatggg
    22801 gggaaatctg ctaagaatgt caaacgcacg cgtgttcgtt ctcgagcgat gagtaccgct
    22861 ttgcgtcgga tttttgatga aacaggcgat gtgtttatca tggggcacaa gtttccggat
    22921 atggatgctt taggctctgc ttttggtgtc agttgtctgg cacgcttcaa ccagaaaaaa
    22981 gcttacatcg ttatcaatga gaacgagatc attccagatg tagaacggtg tcttgaagaa
    23041 atccataagc atcctgaatt agaaatgcaa ctaatctctc cagaacgtgc catagagctg
    23101 aaaaaagaag aggacctcct cgtgatggtg gattaccata aaccttctct atcgatctct
    23161 cagggcctat atgagcaatt tgataagatt gtgatcattg atcaccatcg tcgtggggaa
    23221 gagtttccaa gtaaacctct gctgacttat attgaatctt cagcttcttc agcttcagag
    23281 ctagtttctg agctgatcca ataccaaagc agcaaaacaa atcgcttaga tcgttttgag
    23341 gccacattat tgcttgcagg gatggttgta gatacaaata gtttcaatgt ccgtacaact
    23401 gcacgaactt ttgacgttgc cagctattta aggtcttgtg gagcagacgc atccttagta
    23461 caatatttat tgagctcgga tttagcgaca tacttggaga tcagcaattt gattgctgga
    23521 agcgactatg tgacttctga tattgttgtg gcggcaggga cagacgaaaa agagtataat
    23581 agtgttatag cagcaaaaac agcagataca ttgctttcga tgatcaatat caatgcagct
    23641 ttcgtcatta caaagcggac agacggcttg attgggatca gtgccagaag taccggcacg
    23701 atcaacgtcc aaatcatcat ggaatcctta ggtggcggag gacacttcac aaacgcagct
    23761 actcaactgg aaaatacgac agttgaggaa acaaaacaga agctatttgc tgcaatcaaa
    23821 gaaaatatga atcaaatata tgataaggag taatccaaat gaaagtaatt tttttacaag
    23881 atgtaaaagg aaaaggtaaa aaaggggaca tcaaagaagt tccagcaggt tatgcacaaa
    23941 attatctaat caaaaataac ttggcaaaag aagcaacgaa aagcagtatc agtcagttag
    24001 caggacaaaa gaaagcacaa gaaaaacacg aagctgaaat cttggaagaa gctaaaaagt
    24061 taaaagaatt cttggaaaaa gaagatactg tagtcgaatt gaaggcgaaa gcaggggaag
    24121 acagccgttt gtttggttcg atcccttcaa aacaaattgc tgaagggtta aacaaacaat
    24181 acaaaatcaa attagataaa cgaaaaatcg aattagaaaa tccgatccgt tcactaggct
    24241 acacaaacgt acctgttaag cttcatcatg aggtgacggc tacgatcaaa gttcatgtcg
    24301 tacaagaata acaaatcttg atagcgatgt tcagctggta agtataacca gaaggaaaaa
    24361 agacaaaccg aaatttatct gagaaaacag ctgcagcaat gaaagcaaaa gctgcaaatc
    24421 gatttcagat tgatttcggt ttcttttttg ggaacagcaa aatagcataa agaaaacgag
    24481 tataataaaa gagaactatt tttttattac actttcggta cgaatgatga cttttctctc
    24541 attttcttgt aaaatgaagc aattgaagac aaggagcgat acgtatgaat gaagtgtggc
    24601 aggatcgaat cccaccgcaa aatattgaag ctgaacaagc ggttttaggc tctgtttttc
    24661 ttgacgcaga aacgatcatt gatgccatgg agtacataga gccaaaagac ttttatcgtc
    24721 gtggccatca aattattttt gagacaatga tcgagttaaa tgatcgtaat gaagcgattg
    24781 acgtggttac tgtcaaagac cggctggaac aagccaattt gttagaagat gccggtggtt
    24841 taagttatct ctcagacttg gcattagcag ttccgacagc agcaaatatc gtctactatg
    24901 cgaaaatcgt tgaagaaaaa tcattgctgc gtacattgat ccagacagca acaggaatcg
    24961 ttacgaaagg attcgagcaa ggagaagaag ttcaaacaat tttagatgat gccgaacgca
    25021 gtatcttgga ggtttcggaa aaaagaaatc gaagcggctt tttatctatt gctgaagtac
    25081 tgaactccac gattgaaaat atcgatcgac tagctcaaaa caatgaagaa atcacaggtc
    25141 taccaactgg ctatcaaggt ctggataaaa tgacagcagg tttccagccc gaagaactaa
    25201 tcattcttgc tgcacgtcca gcggtaggta aaacagcgtt tgcattgaat attgctcaaa
    25261 atgtaggaac aaaaacagat cgttctgttg cgatatttag tttggaaatg ggggcagaat
    25321 ctcttgtaaa tcggatgctt tgtgcagaag gttcgattga ggccagccat ttacgtacag
    25381 gtcagctttc ggaagaagaa tggtcgaatc tgatcgttgc gatggggagt ctttctcgag
    25441 caaatatttt tatcgatgat acaccaggga tcaaaatctc tgaaatccgt gcgaaatgtc
    25501 ggaaactagc gcaagaaaaa ggcaatctag gcttgatatt gatcgattat ttgcagttga
    25561 ttgaaggtaa cggtaaagag aaccgtcaac aagaagtatc agatatctct cgccaactga
    25621 aaaaactggc gaaagagctg aaagtacctg tcattgctct ttcacagtta tctcgtggag
    25681 tagaacagcg acaagacaaa cgaccagtgc taagtgatat tcgtgaatcc ggatcaattg
    25741 aacaagatgc ggacatcgta gccttcttgt atcgagatga ttattatgaa agagaaggcg
    25801 gagatgacga tgatggaaac gagccaaaaa atgacaacgt catcgaagtc atcatcgaga
    25861 agaaccgaag cggtgcacga ggaacagttg aactactgtt tatcaaagaa tacaataagt
    25921 tttcgtcgct ttcgccaaga gaagaatttt aaagaagagg ttgtgagcct tgagcaatcc
    25981 cgagagctct cgtaagaaga tgcaaggagt aaccgcagga acgactagag tacttaattt
    26041 aaacagatct ccaaagggat tgtgacaaaa gtcttgtcac agtccctttt tccgaataaa
    26101 cggtgttcaa tcagctgacc cttggtatta gctcagcaaa cgtcaaaata tgaggaacta
    26161 ttttgacgtt tgtttctcta atactcaggt caaaacgctg atcttacgac ctcttttcct
    26221 taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatcatca aacatgagaa
    26281 gcagtttttt gaaattgctc cttgtgactc agagttaaac ggcaggctca caacctcttt
    26341 cttaaacggt gttcaaaagc ttgcatctgc ggtaatacgc ccaatcaaac gaaaaatatg
    26401 agaagctatt tttgtttggc tgttcttatt acttgatgca ggacagcttt ttcacaacct
    26461 ctgattcacg gtgttccaaa agtagcttct tcgaaaaata agtcgaaatt tcacaaaaat
    26521 ttgagaagca attttcgtac attccttctt atttcttgaa gctgaccact tctgttacaa
    26581 cctctttttt aataaccatt ctaaaaagat aaagttcgtt ttttaagcgt ttttataaaa
    26641 taaaaataaa aatcattcga ttttatttga aatatgtatc tattattgat acaatggttc
    26701 aggattaaat aatatagaac gaggtgttca catgtcatct gtagtagtag taggtacgca
    26761 atggggcgat gaagggaaag gaaaaatcac agactttctc agtgaaaatg ctgaagtgat
    26821 tgcacggtac caaggtggcg acaatgcagg gcacacaatt aagtttaacg gtgtgactta
    26881 taaactgcat ttgattcctt ctgggatttt ttataaagac aagatcagtg tgatcggaaa
    26941 cggcgttgta gtcaatccta aatcattggt taaagaatta gcttatttac atgaaaaagg
    27001 tgtagaaaca agtaatttgc gtatttctga ccgcgcgcac gtaatcttgc cttatcatat
    27061 caaattggac caattacaag aagatgctaa gggcgaaaat aagattggta caacgattaa
    27121 aggaatcgga cctgcctata tggataaagc agctcgtgta ggtatccgta ttgcagactt
    27181 attagataaa gaaatttttg aagaacgtct tcgtttgaat ctagatgaca aaaaccgtca
    27241 atttgtaaaa atgtttgatt cagaaccact tgattttgac gatatttttg aagaatatta
    27301 tgaatacgga caacaaatca aacaatacgt cacagatact tccgttatct tgaatgatgc
    27361 tttggatgca ggcaaacgcg tgttgtttga aggcgcacaa ggtgtaatgc tggatatcga
    27421 ccagggaact tatccttttg ttacttcttc taacccagta gccggtgggg taacaatcgg
    27481 aagcggtgta gggccttcaa aaatcaataa agttgtcggc gtctgcaaag cctatacgtc
    27541 acgtgtcggt gatggaccat ttccaactga attatttgat gaaacaggag aacaaatccg
    27601 cgaagtagga cgagaatacg gtacgacaac tggtcgtccg cgtcgtgtag gctggtttga
    27661 ttctgtagtt atgcgccatt ctaaacgagt ttcaggtatt accaacctat ctttaaactc
    27721 gatcgatgta ttaagtggat tggaaacagt aaaaatttgt acggcttatg aattagatgg
    27781 cgaactaatc taccactatc cagcaagctt gaaagagttg aaccgctgca aaccaatcta
    27841 tgaagaattg ccaggctggt cagaagacat tacaggatgc aaaacacttg cagaactgcc
    27901 agaaaacgca cgtaactatg tacgtcgtat ctcagagctt gttggtgtac gtatctcaac
    27961 attttctgtc ggacctgata gaacacaaac aaacatctta gaaagcgtct gggcgcaaat
    28021 ctaaggataa aaacgacgac tgaatcagga cgttcttacc agagcgagtc gaagtgttta
    28081 tctatacgat aataataact tgaagaggta gtgaaagaga cgtttagcct tattgccgat
    28141 aggctgtctc ttgaacactg tttattcaga ataagggact gtgacaaaaa ccgtgtcaca
    28201 gtcccttttt ccgaacaaac ggtgttcaaa agcttgcatc tacggcacta agcccaatca
    28261 gatgaaaaat atggagtgct atttttatct gattgttctt actgcttgat gcagagcagc
    28321 tttttcacaa cctctccact aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca
    28381 atattcaaca aacatgagaa gctgtttttt gaaattgttc cttgtgactc ggagctaaac
    28441 ggcaggctca caacctcttg gtaaacggtg ttcaatcagc tgaccctcgg tattagctca
    28501 aaaaacggca aaatatgagg aactattttt tccgtttttt tctctaatac tcaggtcaaa
    28561 acgctgattt cacaacctct gattcacggt gttccagaag tagcttctac ggaaataagc
    28621 cgaaatttca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct
    28681 gaccacttct gtcacaacct cttattttga ttagaacttg cgaaaataaa ccggttaaag
    28741 tgtgtctagc gcaagagatt tgctataata gacgataagg gtaaaatgta acgagaaggg
    28801 gttgaaaaat gtgtatcaaa ttgtaacaga ttcttgttgt gatctgccat accatgtatt
    28861 agcaaaagaa aaagttgatt ttttatcaat gaatctccaa ttgaatgatc aagagttagt
    28921 agatgacctc ggaaagacat tcaattatga ccgctacatg aatcagctga aaaatggtgc
    28981 gatgcctacg acatcacaaa tcaatgttgg ccgatattta gaatttttcc gttcttatgc
    29041 ggaaaaacag attcctgttt tatatgtggc tttttccagt ggattaagcg gctcttacag
    29101 tagtgcgctt caagcggttg aattgctgaa ggaagaatat gaagaccctg agatctatgt
    29161 ttttgataca aaagctgcaa gtattgggga agggctttta gtattggaag ctgtaagatt
    29221 gaaaaaagaa ggtaaaagca tcgaagaaac cctagagtgg ctggaaagta attatttgaa
    29281 agtccattca tgggtaacag tagacgatct gaaatatcta gaacgaggcg gtaggatttc
    29341 caaagcaagt gctactcttg gcagtctatt gagtgtaaag cctattatta cggtggataa
    29401 agaaggaagg ctgacgaatg ttgacaaagt tcgaggaaga aacaagtcga tccagacaat
    29461 cgtcaatgag acggtaaaaa caatcgttgc accacttgat caaatcgttt atgtggctta
    29521 cgctggggat ctagagagcg cggagaaggc aaaacggctt ttggaagagc agataaagat
    29581 gaaagatgtg aagctttatc ccttaggacc aacgatcgcc agtcacacag gctatggctg
    29641 tatcgcgatt ttttcgatgg gaatcagtcg ataaaagcag taactcattc tgtaaaaaag
    29701 cccagaaatt gattgtaaca aaaacagcga ctcttaaaag atagatgagc atcctatctc
    29761 ttagaggtcg ctgttttttt attttttaag ctaaataggc cattatgccc ataactcgtt
    29821 caattgtttt tgaatatctg cattttccaa aaattcatca tatgtcgtat cagctcgatc
    29881 gatcacacct ttatccgaaa cggcaatgat gcggtttgcc aatgtttgga taaattgatg
    29941 gtcatgtgac gcaaataaga ttgagccagt aaatgccatc aagccgtcat tcaatgctgt
    30001 gattgattct aagtctaaat ggttcgttgg atcatctaat acaagtacgt tagctttcga
    30061 aagcatcatt tttgaaagca tgcaacggac tttctctcca ccagataaaa cattcactgg
    30121 tttcaatact tcttcaccag aaaacaacat tcttcctaag aagcttctta agaaggtgtt
    30181 atcatcttct tctttacttg catattgacg caaccagtct aaaatcgtta gatcagtatc
    30241 gaattctttc gttgtatcct ttggtaaata agaattactt gttgtcacac cccaacgtac
    30301 tgttccagta tctggcgtaa tttcacccat gataactttg aatagcgttg ttgttgttat
    30361 atcattttct gcgacgaaag cgaccttgtc ttctttgctc aaattaaaag atatatcatc
    30421 taaaattttc tttccatcaa tcgttacact tacattttct acctgcaata agtcgtttcc
    30481 aatctcacgt tcaggtttga atccaacgaa tggataacgt ctagaagaag gttggatatc
    30541 gtctaaagta attttttcaa gcattttttt acgtgaagtt gcttgttttg attttgatgc
    30601 attcgcacta aagcgggcaa taaattcttg gagttctttg atttgttctt cttttttggc
    30661 atttgcgttt gcttgaagtt tagccgctag ttgactagat tccaaccaaa aatcataatt
    30721 tcctacataa agtttgattt taccaaaatc tagatccgcc atatgtgtac atactttgtt
    30781 caaaaagtga cggtcatggg atacaacgat cacagtattt tcaaaattga tcaaaaattc
    30841 ttccagccaa ttgatcgatt ggatatccag accgtttgtt ggttcgtcta gcaaaagaac
    30901 atcaggttta ccaaatagtg tttgtgctaa taacactttt accttttgtc caccagttaa
    30961 ttcactcatt tgctgatggt gcaattcttc agggatgttc agaccttgca gtaaaacagc
    31021 tgcttctggt tcagcttccc atccattaag ctcagcaaat tctccttcta attcagctgc
    31081 tcgaatacca tcttcgtcag tgaaatcctc tttcatgtaa atcgcatctt tttctttcag
    31141 cacttcatac agacgcttgt gtcccatgat gactgtttca agtacagtat agtcttcata
    31201 gtcgtaatgg ttctgtttca atacggccat ccgttcatct ggtcccatag taacggaacc
    31261 tgtggaaggc tgcagatccc ctgataacac tttaaggaac gttgatttac ctgcaccatt
    31321 tgcaccaatc aagccatagc agtttccggg ggtaaattta atattcacat catcaaatag
    31381 tttgcggtct gaaaagtgca aactcacatc atttacagta atcaattttt ttcctcactt
    31441 ttatcattat tagttttgac aagtcttata gaattatata ggggaaaggt aaaagattca
    31501 aggcaatcga acattctttg tgtttcacgt gaaacagaat gaaaaaaata aaaataaaag
    31561 cggagcgaaa atagctacta taggatttat tagtttgcaa cagcataatt tttgacgtta
    31621 tttataagag ggagtactat aaaactgtaa aagaaatgaa agaaggattg aaaatggatg
    31681 aaaaaagaac catcgactgg ggctcattga ttttgggaat tttatttgta cttgtctcat
    31741 tgttatcatt tcaagaccct gtcggaaatt tagttgcaat tgtagtagtc tttgcgattt
    31801 ttgcctttat taaagggata tttgaactgt ttgtacggaa cagattaaaa gagctaacag
    31861 gatataaagg aaagatgccc ttaataatcg ggatcatcga tattctagtt ggcgtctttt
    31921 tcttattcaa tattggtgca ggagtcgcag cattgccttt tgtttttgca gtatggttta
    31981 ttgctgattc agttttagcg ttatttactg ctgacttggc aagaggagta agtgaaggat
    32041 attattggtt tacgatcatc gtcaatattt taggaatttt attaggaatt ttcttattgt
    32101 ttaatccaat ttcttctgtg ttgacattaa gctttttagt tggattctat tttatgttat
    32161 ttggtatcac acatatcgtc tatgcattta gataagtaaa atcaaacaaa taaaaaagcc
    32221 ggcttccgat tacagtttta ctgttgtaat tggaagccgg cttttttatc atggacaaat
    32281 atgcacgagg tgatttttag gtgtcgagac aaatttatgc aaaaatgtga gaagctatat
    32341 acacaaattt tatcttaata ctcgaagcat agcgcagttg tcacaacctc ttttcatata
    32401 attcattcaa tactggcaaa tcatggactt catatttttc tttgaatgct tggatttctt
    32461 cttcagaata ttttcttgga tctaaatgca gatcttctac tggcaatggg cgcttgttat
    32521 tgatcttcac atcgattact acaggacgat ctgattttgc agctgcatca aaggcaaatc
    32581 gaagttgcga gtattctgtg actgtaaagc tatttgcccc gagcgcttct ccaactttac
    32641 cgaaatctgc atcttctaaa aatacaccaa atttcttttg ttccgtatct tcttgttctg
    32701 cttcgatgaa accaaaagaa tcattcgaaa agacaacatt aataattgga agctgatatt
    32761 tgacttgtgt aatgatatct tgcatgacca tagcaaaccc gccatcacca cttaaggtaa
    32821 atacttgttt ttctgggtag cttagttgtg cggcaattcc tcctggcaca ccattaccca
    32881 tagttgcgaa ccatccagat gtcgtatgtt tttgtttacc gttcatattc aataaacgaa
    32941 tagaatggat agtcgtgtta ccgacatctg tgacgaaaat cgcatcgtct tcagcaatac
    33001 gattgatttc tttatagaca gcctctggac gaatcggttc ttcctctcga tcttcaaaag
    33061 atttcaacca atttacccat ttttctttat tttcttgatt tgctaggtac cagctatcag
    33121 cagggcgagc atcccctaac tcgacaagtc tttgcaaagc tgtgtttgca tcaccgagga
    33181 tcgacaaaga tgtttcatgg cgtcgtccaa attttgacgc atcgatatcg atttggataa
    33241 attcagcagt tggattaaaa aatgcacgtc caaatgggaa gtcgctaccg acaaataaga
    33301 tcagatcggc ttctgccaat gcttcatttc cgggtttagt agcgacacgt ccagcaaaac
    33361 caagaaagtt ttcataatca tcaggaataa ttccttttgc tagaacggaa gcgacaacag
    33421 gaactgaaaa atgttctgag aattctttga tttgcggaaa tccgtttcgc gttccttgac
    33481 caacataaag aactggtttt tttgcttttt caagataagg caaagcagct agcaaatctt
    33541 tttcttctgg taatatcaca cttgttttgt gagtgtgagc ggtggagaaa ggttgttcgt
    33601 caatttcttc aaaaccaaga tcaacaggga tagtcacgat agccacgcct ttatgctcat
    33661 aggcggcttt aatggcttca tctactacat gcggaagact ttgtggtgtc atgactgtac
    33721 gattgtatac gctaacatct gcgaaaatag gattttcatt tagttcctgg aaagagttat
    33781 agttcatgga tgtagaagca acttgtccta agaacgctac tagaggcaca tggtccatct
    33841 gtgcatcata caaaccattg atcaaatgtg tcgcaccagg tcctgcagag ccgaagacag
    33901 cgccgacttt ccccgttaat tttgcatctg cagcggctgc gagtgcgccg acttcttcat
    33961 gacgaacttg aatgtagttg atttcggttt tttcttgata tagcgcatcc ataattgaat
    34021 tgaaagatcc tccgggaatg ccgtaaatat ggtcgatacc ccagctttca agaactttta
    34081 ccattgcgat tcctgcattg atttttgaca tggtgtttca ctcctttagc aatgatgata
    34141 cataaatttt ttgtatctag agtatagaac tttttatcga aaatcccaac taattcgtct
    34201 tttcacaaaa atgtagtcat gtttttggga atatgctaga gtagtacata gatagattca
    34261 agagagggga atggcatggt tgaatggcta ttgagacttg aaccttggca gcaagcactt
    34321 gctgggacag cttttactta ttttatgaca gctcttggtg ccgggttggt ttttttcttt
    34381 aaagaaatca aaaaagaagt gctaaacttg atgttaggat ttgcttctgg tgtcatgatt
    34441 gctgcaagtt tttggtcttt gttagatccg gctattacaa aagcagaaga aaatggagat
    34501 attgcttggc tagttgtaag tattgggttt ggtttaggcg gtgtgttttt atatatggca
    34561 gataaaacac tgccccatat gcattttgga ccacaacatg aagcagaagg attgcctacc
    34621 catttaaaac ggacgatctt gcttgttttt tctattacat tgcataacat tcctgaaggt
    34681 ttagccgtgg gggtagcatt cggtgcagca gcaactgcgg ataatccgac agccgctata
    34741 ttagccgctg tttcggtggc gctaggtatt ggtatccaaa acttcccaga aggagcagct
    34801 gtatcaatcc cgttgcgaca agaaggtctg agtcgtaaaa aggcctttgt ttacggacaa
    34861 gcttctggaa tcgttgaacc aattgctgga gtgattggag cgctactagt aacgaaagtg
    34921 gagctgctgc ttccttatgc acttgctttt gccgcaggag caatgattta tgtcgtggtg
    34981 gaagaattga tccctgaagc acagcagaca ttgtccagca aacgtcattt tgcagttttt
    35041 ggcgtcatga gtggatttat cattatgatg attttggatg tggcattagg ataaataaaa
    35101 aaaatatata tgatatatca aatagggccg cgaacttata t
//
LOCUS       DAXLPY010000022        33127 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.022, whole genome shotgun sequence.
ACCESSION   DAXLPY010000022 DAXLPY010000000
VERSION     DAXLPY010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.022"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(94..951)
                     /locus_tag="ACF3UF_001203"
     CDS             complement(94..951)
                     /locus_tag="ACF3UF_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3671348.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(1059..2362)
                     /locus_tag="ACF3UF_001204"
                     /pseudo
     CDS             complement(1059..2362)
                     /locus_tag="ACF3UF_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(2359..2868)
                     /locus_tag="ACF3UF_001205"
     CDS             complement(2359..2868)
                     /locus_tag="ACF3UF_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671349.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(3043..5178)
                     /locus_tag="ACF3UF_001206"
     CDS             complement(3043..5178)
                     /locus_tag="ACF3UF_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFD3671350.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(5261..6916)
                     /locus_tag="ACF3UF_001207"
     CDS             complement(5261..6916)
                     /locus_tag="ACF3UF_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3671351.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(6918..7232)
                     /locus_tag="ACF3UF_001208"
     CDS             complement(6918..7232)
                     /locus_tag="ACF3UF_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFD3671352.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            7402..7662
                     /locus_tag="ACF3UF_001209"
     CDS             7402..7662
                     /locus_tag="ACF3UF_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFD3671353.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            7676..7990
                     /locus_tag="ACF3UF_001210"
     CDS             7676..7990
                     /locus_tag="ACF3UF_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFD3671354.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(8720..9274)
                     /locus_tag="ACF3UF_001211"
     CDS             complement(8720..9274)
                     /locus_tag="ACF3UF_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFD3671355.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(9400..11328)
                     /locus_tag="ACF3UF_001212"
     CDS             complement(9400..11328)
                     /locus_tag="ACF3UF_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFD3671356.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(11634..12350)
                     /locus_tag="ACF3UF_001213"
     CDS             complement(11634..12350)
                     /locus_tag="ACF3UF_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFD3671357.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(12351..14174)
                     /gene="glpO"
                     /locus_tag="ACF3UF_001214"
     CDS             complement(12351..14174)
                     /gene="glpO"
                     /locus_tag="ACF3UF_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFD3671358.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLIPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(14188..15684)
                     /gene="glpK"
                     /locus_tag="ACF3UF_001215"
     CDS             complement(14188..15684)
                     /gene="glpK"
                     /locus_tag="ACF3UF_001215"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFD3671359.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(15820..17280)
                     /locus_tag="ACF3UF_001216"
     CDS             complement(15820..17280)
                     /locus_tag="ACF3UF_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3671360.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(17270..18565)
                     /locus_tag="ACF3UF_001217"
     CDS             complement(17270..18565)
                     /locus_tag="ACF3UF_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3671361.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(18897..19574)
                     /locus_tag="ACF3UF_001218"
     CDS             complement(18897..19574)
                     /locus_tag="ACF3UF_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFD3671362.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(19604..20695)
                     /locus_tag="ACF3UF_001219"
     CDS             complement(19604..20695)
                     /locus_tag="ACF3UF_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFD3671363.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(20796..21230)
                     /locus_tag="ACF3UF_001220"
     CDS             complement(20796..21230)
                     /locus_tag="ACF3UF_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFD3671364.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(21814..23271)
                     /locus_tag="ACF3UF_001221"
     CDS             complement(21814..23271)
                     /locus_tag="ACF3UF_001221"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3671365.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(23268..25163)
                     /locus_tag="ACF3UF_001222"
     CDS             complement(23268..25163)
                     /locus_tag="ACF3UF_001222"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFD3671366.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(25221..26996)
                     /locus_tag="ACF3UF_001223"
     CDS             complement(25221..26996)
                     /locus_tag="ACF3UF_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFD3671367.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(27046..28542)
                     /locus_tag="ACF3UF_001224"
     CDS             complement(27046..28542)
                     /locus_tag="ACF3UF_001224"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3671368.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(28736..30358)
                     /locus_tag="ACF3UF_001225"
     CDS             complement(28736..30358)
                     /locus_tag="ACF3UF_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFD3671369.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(30808..32121)
                     /locus_tag="ACF3UF_001226"
     CDS             complement(30808..32121)
                     /locus_tag="ACF3UF_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFD3671370.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(32366..32590)
                     /locus_tag="ACF3UF_001227"
     CDS             complement(32366..32590)
                     /locus_tag="ACF3UF_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671371.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(32610..33032)
                     /locus_tag="ACF3UF_001228"
     CDS             complement(32610..33032)
                     /locus_tag="ACF3UF_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3671372.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
BASE COUNT         9462 a         7107 c         5512 g        11046 t
ORIGIN      
        1 aataactaaa gagagatggg acatgtagtg gcactcaaga attagatttt tcagtctaac
       61 ttcgaggtac tctaccttcc catcctctct tttttatttc tttttgcgga tgattccgta
      121 agctgctgcg actaacacac ccgcccctgc taaggaataa ctgacagaag ctgttttttc
      181 atttgttttt ggcaaagtct gacttgttga tttggatggc tctgtcgttt gctgaactgt
      241 ttctgtcgtg cttccagagg tcactgattt ttctcctgcc gaatgcaaaa tatcttttat
      301 tcgttggaaa ctagctgcta agtcagcttt ttttgcttca aaatcattag caactgtttg
      361 tgcttcgctg atctttccgt ggattgcttg acttgccgct gtgatatccg cttgagtttg
      421 acttagcttt ccagaagctg tttgagcaac ctgatttaat tgctgattga attcttttgc
      481 ttgttggatc ttcccgtcaa gatctgtttg gacagcttcc gcttttgctt tcgcttcggc
      541 aagctttttc tcaagttgtg cacggtcatt tcccacttta tttttaagat cagctaaatc
      601 ttgatcgatt gctgcttggt cttctttcaa tttgtttttt gcagcttcta atgcttcttc
      661 gagttctttt cttttatttt ccaagtcttg caaatgatcg atttggtcag aagaggtaga
      721 actatttatt gatgtatctt ctgaagatga aatcgtttct cctgaattat ctgtcggtac
      781 attggaagtc atttctgttt ccgaggcacc gttttcagca ccagaagagc ttatagttgt
      841 tgaaggttct gtttgagcag gttcagaagt ttccgcaaaa gctgtctgtc ccaataagaa
      901 aatactggaa acagcaattg gccagattaa cggcttcatt ctttttttca tcacttttcc
      961 catccttact actttttaac taatttctta ttataagcaa aaatgtttgg aagaaccata
     1021 aacacaacag gctgtttgtc taaaaaacgg tgcatctttt atttttttgt acgttccggg
     1081 cttttccatg tcccgcttcc ataacctaaa atcgttttga ctgctggaat gaaagtcgtc
     1141 acgatcgtta tcgcgttcac tatccagaac aaaagcatat atagtggtgc gaaaagaagg
     1201 tatttcaatt ttcttcgtcg atcatctaca atcagcgaag ctagcaactg gaaaaatcct
     1261 gcgaccattt caaagcagat gaacacaaaa ctgaatgtaa aagtaatata aatctgttcg
     1321 tagtttcctt gatatacata atgcccgatt aatccagcaa aaagaactac ggaaatacaa
     1381 aagaatattg accagacaat actcaatgtt tgatcaatga agatgatcgt tcttccaata
     1441 tgtttaaaag gatggagcat cacttttttg aaattcgtca gccagacttc tgttccacct
     1501 tttgcccaac gttttctttg tcgatatagc atcttcaacg tcacaggtac ttccatgaaa
     1561 aagataatct caggagcaaa aacagataac cagtcattta actgatgatc ccaagcaata
     1621 ctgatgtctt ctgtcgctcg atcttgtctg aatccgccca catcgatcaa ggcttctttt
     1681 cgatacatcg tatttgctcc actgtacgca taaagaccac cgaaaacagc tgactgtgtt
     1741 cgtttaatga tgcccacgat acttgagaat tcaaccgttt gagattttgc aatcaatttg
     1801 gtacgatttt ggacatccat atttgcagtg accgcagcaa tatgtcttgc accagggcga
     1861 atgaaataat tcacatacct aatcagtgca tctggctccg gtaccgtgtc tgcatcattg
     1921 cttaaaatca atttcccttt tgcaaaggca agtccgatat taaacgcgtg ggcttttcct
     1981 ttattttttt cgatccgaac cacacgaaga ttagcgtatt ttttcatcag tctagctaat
     2041 atttctggtg tttggtccgt tgaaccatcg tctgtcacta atacctcata gttgtgataa
     2101 ttcaatttcg tcatcaaata ctcgattgta tcttcgatca caatttcttc attatgggct
     2161 ggcaccatga tcgtgatgaa cggttcgaca ctcaagggaa catctaccca ttctttttgc
     2221 ttatgtttgt ataaaaacac ataacaccag acaccaataa accatacaaa tccgcctaaa
     2281 atcggataag aaacgagaaa aaatacataa tagacaaaca agtatctaag aataaattac
     2341 ctgtatgggt gattgagatc atttcagttc caccccattt tctttataca aatctgcaat
     2401 gaatgtcgta tctagatttt tctcttcgga gacagaataa aaacggaccg tttctctctc
     2461 ttcttttgtt ccaaaacgtt ccgtatacac ttcttcaagt aattcttgtc tttttttcaa
     2521 tttttcatct tcatattcaa aagatttatt tacttttttg tatagatttc gattgttcca
     2581 cctagtcaat acaaatgagg taatcaggaa actgaaaaaa atcaatacaa aaaagccgat
     2641 taagaaatac agcattttct tttctgataa aaaagcgtac aaggaaaaat ccttggctct
     2701 ttctggtctc gttaatggga aaaagaccca tataaaagga agaacaacga tcatccatcc
     2761 taaaagagcc actaacgttt gccaaatctt taaccagtaa ttaccttttg aaaaatactt
     2821 atctttcacc aaaattgatg caacttcttc tcttgttact tttttcatat cctcacctca
     2881 cgtttttttg ttacgacgta ggagtttacc atacatttca tttcttttca cataaagtgt
     2941 tcctaaattt ttcctaagaa aaagaacaaa acatttctca tcagtaaatg aaaaatattt
     3001 tgttcttttt atcagttgtt ctttttattt tttatctctt aattatgttg ctctttccaa
     3061 tacgacaatg cttttcattc ctctagatat cgccgtgtac atttgtctgc gtcttctttg
     3121 ctcatctcca tcgttttcaa atggatataa gattacatga tcaaattcca gtccttttgc
     3181 tagactcaaa ggaatgattt ggcagttttc taatccatat gaattttttt taatcgattc
     3241 ttgtagcgtt tgggtttcct cttctgtttg ggtgataact gccgcttttt ctccttttag
     3301 agaaaccaaa atctcagcta gtattttcaa caattcttca gaggatcgaa aagagcggta
     3361 ttcgggttct tttccttgcg gtcggatcga tacgatgtcg atcttctctt gatccacagc
     3421 ataggttttg aaaagctctg tgattgctcc gctagaacgg taactatttc taagatcata
     3481 ccgatggatc ggcagatggt agtcgtcgaa acaacgcata atatcagcaa aagtagtgga
     3541 agaattaaag attgcctgat tctcgtcacc tactaaagta aagtgagttt ttggaaataa
     3601 ttcgatcaat agacctaatt gtgccagggt ataatcttgt acttcatcaa tcaatagata
     3661 gcgaaatgct ggtacattta ccttttcaac aagtaaatga cgaatagcta atataatgac
     3721 tgcttcatca acagtacgtg tgggttgcca agcataagct gagccatatc gtttttcata
     3781 aattctttca aacaactgat gctcatccac ccatgccatt tcttcgattt gtctggttat
     3841 ttttcgatat tttttttgta aaagtttcct tgcataagct acaatacttt gttccgaatc
     3901 atcagaaatc aatttaccga ataattccaa ctgcctatct tctgtcaacg agagtacctg
     3961 attctgcaca gcaggacttt ttgcttgttt caaaagatga ttcttccatt cgctcatcag
     4021 tgcctttttc gttgcttgaa gcctatcgat caatttagga tgagcaggaa ctttctcata
     4081 tattttttcg atcgtttttt tagaaaggac tgtttttcca tttttagtaa gtccacggat
     4141 aaaattcgga tgatctaaaa acaaaggatc tgattgtttt agattatcga taaacttttt
     4201 gctacgcaaa cgttctgtct gctccgatac attttctccc gtgatacgtt tgaaataagc
     4261 ctcttcacct tctatttcct ctgctgaaag ctgtgaaacc agctgtatga tggttagatt
     4321 cagtggattt ctttcaccta atgatggtag gacattcgaa atatagtcga taaaccgatg
     4381 attaggtgat agaatcagca agtcatcgga tgtcatcgta tctcgatata aatagagcag
     4441 atacgcaata cgctgcatga tagcagaggt tttaccactt cctgctacgc catttaccaa
     4501 gatattttga cttttcacat cccgaatgat tgtgttttgt tccgattgga tcgtagcagt
     4561 gatagccttc atttcattgg tctcatcttg gcctaagact tctaataata cgtcatcttg
     4621 aatagctaca gacgtatcaa aaaacttgac caaacgatct ctttccaaaa gaaattgtcg
     4681 tctttcttta ataaccgtat cgattttatt ttgacgaacc gtataagaag atggaccaat
     4741 catgttattg taaaaaagtt cggcaattgg tgaacgccaa tcataaacaa gattttcatc
     4801 tgcatcatct gtgaaatttg ctgtaccgat ataaaaggat tcttttggct cattatccag
     4861 aaagtctaca acgacttttc caaagtaggg acttttcaat aaacgttcga tctttgctag
     4921 ctgattttct gcgtttttct gtttgatatt catctgatcg atttctctat ttttcatttc
     4981 aatcatcgaa aaagtatcca ggttatctaa gtaactgtca aaattcaatc gaagctcgcc
     5041 agccatttct ttcaacgact ggtttccttc tatttttgcc gtatccatcg attcccgcag
     5101 ttcgtttttt ttatcaatta gcttttgata cacgttcttc agatatgctt cttctaactg
     5161 tttttgtgtg ttgaccatac acattctcct ctttttttaa agtggtggaa ccgattagtt
     5221 tacctctttt aagagtcgaa tgcaagcttt ttaacgagta tcatttgtta ggatatatca
     5281 gttcttcagg tcggacagtt tgatataaag aaaatgcacc atcaaggttt tttacgtggt
     5341 agccagactg cttcaagatt ctttccgcta gatagctacg taatccgcta tgacagctga
     5401 cgatatattc ttgttggctg tctaattcat ttaatcggtc ccgaagttca ttcaaaggga
     5461 tatgtttggc ttccttgaat ttgccctttt ccaattcttc tgctgttcgc acatctaata
     5521 aaatttttcc ttttgctagt tctgtcggca attcatgcca ttgtacggtt tcactaagcc
     5581 cttctgcaat gttcattgct gcatatccta gcatgtttac tggatctttg gctgagccaa
     5641 atggcggtgc atacgtcaat tctaattccg gtaaatcgaa gatcgtcaaa tgccctttga
     5701 ttgctgttgc taaaatatcg atccgtttat ccacaccttt tgccccaaca ccttgtgcac
     5761 cataaatctc gccagtctct ggatggaaga tcaacttcag taaaatatct gttgcttctg
     5821 gataatagct tgcatgatct tttcctgata catgaatgac ttcaaaagac agttcgtttt
     5881 ctttggctgt tctttcactt aaaccggtgg atgcggcagt cattccaaac gttcgtataa
     5941 ttgctgttcc aataccgcct tgatttcttc gagaaattcc ggaaatcgtg tccgcaactt
     6001 gtctaccttg acgattggct ggtgaagcaa gagaaataag tgcatctttt ccagtgattt
     6061 gctgttttac aacgatagca tcccccaccg cataaatatc aggaatattc gtttgataac
     6121 gttcgtctac taggataccc ccgcgtatgc ctaattcgat tccagcggtc actgctagct
     6181 ggttatcagg acgaacacca atggataaaa taactaaatc agcagggatg gtacgcccat
     6241 catccagtcg caatcgtttc ccgtggtctt caaatccagc gacagcatga gaagtaatca
     6301 cttctactcc ttgatgagac aattcttttt ctataaaagc tgccatttct tcatccagtg
     6361 ttggaagaat atgtggtgct tgttcgatca ccatgacttc taaacctctt ctttttaggt
     6421 tttctgccat ttccaatccg atgaatcctg caccaacgat cacggcacgc tttggctgtt
     6481 tttctaatgc atgcatcact ttatcgatat ctggtacatt tctaatagaa aaaacattgt
     6541 cggcttctgt tatccctgga atcgatggaa caactggttt tgcaccagga gataaaacca
     6601 atgcatcgta ctgttcaatg tgtttttgac cctcatgtac gacttctacc gttttgtttt
     6661 cgggaaagat ggctgtcact tcatgatttg gacgcacatc taaacaaaaa cgagcggata
     6721 atgattctgg cgtttggaca agaagatttt cccgttcact gatttctccc gaaagataat
     6781 aaggcaagcc gcaatttgca aaagaaacat acggtccttt ttcaaaaaca acgatttctg
     6841 catcttccat taatcggcga agccgtgtag cagcagacat tccacctgct acacctccga
     6901 caataacgat tttcatctta tttccctcct actgttcgat caaaccattg attcatgcca
     6961 ccacgtacat tcactacatc ataaccagat ttctttaatt ctttagctgc ttgtttactc
     7021 ctcatccctg attgacaaat cacatagacg gtcttttctt tgtctccatc atatctgttt
     7081 atactttgta atggaacatt tttagctcct tttatatgcc cgccccggta ttctgcaggt
     7141 gttctaacat caagtaacgc tggattttcc aaaagctttt cctttaattc tgggactgtt
     7201 atcgatttta ttgattgaaa tagcaaattc attttctgca cctcatttac atttttataa
     7261 atacctcatg gggtatatta aacaggagct ttattaatat gtcaaccaga atgactcttc
     7321 atttttttca ctacttttta tatttgcata aaataccgat aaggggtatt atctaattat
     7381 aaaaatagag gagaatgtgt tatggagatt gataataaaa atatcctgaa ccgtttgaaa
     7441 cgtacagagg gacaaattcg tggtatccaa aaaatgatcg aagacgaaaa agaatgtatg
     7501 gatgtcatca ctcaattaag cgctgttcgt tctagtattg atcgcgtaat gggcatgatc
     7561 gttgcagata atctgaaaaa ttgctttgag aaacctgata gtaatccaga agaacaagcg
     7621 gctaaactag aacaagcgat caagatgatt attaaaaagt aaaggaatga tttcaatgaa
     7681 agtcgttttc catattgatg aattagaaaa atggtcagaa acagggaaaa acgtaaaaaa
     7741 cctgataaaa gcttctccag aaacgacgat tgtcgtatct gtaaatggca tcgcgattac
     7801 cggttatcta gactctgcca atgcagaatt cttagatttg caaggagtcg tttttcacgc
     7861 ttgcgccaat gctatgcgtg ctaatcatat ttcagaaagt tctttacctg aacaagtaat
     7921 cgttgtacca gcaggtgtcc ttgatttagt tgaactgcaa tcccaaggtt atgcttatat
     7981 caagccttag tcagtagagg ttgcgacaga agtgatcagc ttcaagaaat ttcggcttat
     8041 ttttcgaaga agctacttct ggaaaaccgt gaatcaaagg ttgtgaaaac gctgtcctgc
     8101 atcaagtaat aagaacagcc aaacaaaaat agcttctcat atttttcgtt tggttgggct
     8161 tattaccgca gatgcaagct tttgaacacc gtttaaggaa gaggttgtga aatcagcggt
     8221 ttgacctaag tattagagaa aaaaacggga aaatagctcc tcatattttg ccgttttttg
     8281 agctaatacc gaaggtcagc tgattgaaca ccgtttaagg aagagattgt gaaaaagtcg
     8341 cttagtttcg agtattaaga aaaattttgt gaaaatggat ttctacattt ttgcataaat
     8401 ttggcttaat accgagaaac tggcttttga ataccgttta aggaagaggt tgtaaaatca
     8461 gcggtttgac ctgagtatta gagaaacaaa cggaaaaata gctgctcata ttttgccgtt
     8521 ttttgagcta ataccgaagg tcagctgatt gaacaccgtt taccaagagg ttgtgagcct
     8581 accatttaac tccgaatcac aagaaataat ttcaaaaaca acttctcctg tttttggttt
     8641 ggttggctta ttatcgagaa gtagctactg ggagtctatt tatcaaaaaa aggaatgcga
     8701 cataggtcac accccttttt tattttcttt gaaacatctt tcggtactcg acagcataca
     8761 agacaaaaga ttgtaaaaga ccgtaagtga tgacggcaaa aatgactctc acccacagcg
     8821 ttggtaattc tgggaaaagc agcaaaagga tcatgccaac atagatgaca gcagtcgcta
     8881 ctttgccata ccacttcgct ccacttaatt tgatattttt agatagcccg attaatccag
     8941 ctacaaacat aaagccttct tttatcaaga atagaccaaa caacagccaa agccacggtc
     9001 gataccatgc catagacaaa atcagaaaaa gttgtgtcaa tttatctgca aacggatcaa
     9061 gcaccttccc taagtctgtt acctgattat atctccgagc aatgaccccg tctagataat
     9121 cagacaaacc tgagacaaca atgaccgctc ctgctatata aaatgactgt ctcagcacaa
     9181 aataaagata aatcggcagc aaaaaaatac ggaatatcga taaaagattc ggaatcgttt
     9241 gtatttcttt acgccagtct gtgcttaatt tcattttatc gccctacctc ctcagcactc
     9301 ttttcttttt attttagctt acacggggaa taaaaccaat gatttcactg tttttatttt
     9361 tctttacagc cactgatatt atgagctaat ttgagataat cacttgctgt tttcatcgtt
     9421 tactcttctt tcttcctgtc gtttgcgcat ttcttttact agtactttat gagctttttt
     9481 tgatcctcgc tctaggtcac gctgccgttt acgtgtttta taatcgataa acagactgtc
     9541 taaatcgtaa cctgtcgggt acagatcttc tgctgaacgc accagacgaa cacgctgacg
     9601 aggcacgtgg attatttttt tgtctaaata tacatcaatc gtatcttcac ctatatcttc
     9661 ataaactaac gcttcttttt ggtattcatt gacaaatatc cgatcacctt ttgcaaagag
     9721 ctggcgttct tttttattct ccttcctatt tgtaactgct gtcttaggaa gaaattcttt
     9781 tttctgtgtc cgataggctt tttccgccaa gtaacgctct gcttgatgga tcaatttcat
     9841 cgacatatcc attttatgag caatccacaa agcttggctt tctcctgttt ctccaacccg
     9901 caactgatat ttaggacgaa gtgcttcccg atcgaaagcc atagcagccg gcacaaaatc
     9961 ttcatgatct ccggcgaatt tcttgatttc tccataatgg gtcgtggcaa tgatcaatgc
    10021 cccttgctca tacatagatt ccatgattgc gatcgctagt gcagcccctt catttggctc
    10081 tgttccactg ccaatctcat ctaaaagtac caacgtattc ctttttatct ttttcaaaat
    10141 agcagcgatg ttttgcatat gaccagaaaa tgtactcaac gcattttcta aattttggtg
    10201 gtcaccgaca tcgacgaaaa tctcatcaaa gacagcaagc tctgtccctt cttttgccgg
    10261 aacttgcata ccgaacatcg ccatcaaagt caataaaccg actgtcttca acacgactgt
    10321 tttgcctccg gcatttgctc cggtgataat caagcctcga tagtctttac cgatttcaac
    10381 atccaatggt accgcatgct caggtaaaaa tggatgtctg ccttgcttga taatgatatg
    10441 ttccgattta ttgattctag gtgtgcttcc attgatttct cggctaaatt ttgcccgagc
    10501 aaagatgata tctaacaccg tgatcgtttc gatcaataaa tcgatcactt cttcgttttc
    10561 tgcgatagca ccagtcaatg ccgccaggac ttgatattct tcactgattt cttcagcttt
    10621 taacaactga tagtgttcat tcaatttaga aatcacagtt ggttcaataa aaaccgtcgt
    10681 tcttttattt gattcatcga taatcgttcc atctatttta tttttatagc tggctttgat
    10741 aggaatcgta tagtattcgc ctttttgaac aatcattgct tcttggatca tttctttgtt
    10801 tttcggatga cgcaagaatt tcagtaattt tgactggatt tctttttcga ttagttgtaa
    10861 ttgtttgcgt actttacgca aattacgtga cgcgtcgtca ctgactttat tattttttat
    10921 tttctggtca atcaactctt ctacatttat caaatcagga agatgtttgc tataagcaaa
    10981 caacaagggt gtctggtatt gattcttatc aaaaaacttt gtgatcatcc gactgcttct
    11041 aagaaaatcc gcatattcga tcaaatcggt tggctgcaga atcaaccctt ttttgacttg
    11101 ttctgtcagt gcatcgatcc tcggcaaccc cataaatgga acatgctgac tgctttctaa
    11161 gatcaagcgt gcttctcttg tttcttcttg acgatccaag acagtttgta ggtttgtcga
    11221 gaccgtcata tcgctgattc gttttttgct atagtttcca attgctcttg cttggatttc
    11281 ctttttgatc cgatcaaatt gtaattgact aatcatttcg ttgtccatat tctctccttt
    11341 tcttgaagag atacctgtcc caaaataaat aagggcctag agataaataa aaggatagaa
    11401 cacagcttaa aaaagtcatg tcctatcctt attagaatac aaagatattg ttttcctgac
    11461 aggtaccgtt tcataagcac accaaataaa ctttgtttat tggctattcg acttactgat
    11521 tagataccag ctacactcac aaaacatacc ccattcttct aggtcttatt tattttccac
    11581 ttaactatag caagacacat tttggttgtc aaactttagt atgttttata gatttacacc
    11641 attaatgaat agacacctac cgcgataatt gctccgatca ttggacctgc gattggtacc
    11701 catgaatatg cccaatctga agttccttta ttagctattg gcaataccgc atgtgctaat
    11761 cgaggaccaa agtcccgagc agggttgatt gcatatcctg ttggccctcc taatgaaaga
    11821 ccgatggcta agatcaatcc acctacagcg aatacgttcg ttccaggtgc aaattcgttt
    11881 tgtccaaaag ctagcaaccc aagaactaat acaaatgtac caattaattc tgtgatcaca
    11941 tttgctggat aattccgtat agcaggacct gttgcaaacg ttcctaaaat cgcgctttca
    12001 tctttcgttg cattccaatg tggcaaataa gaaagccaaa caagaatggc ccctgcaaaa
    12061 gctcctaaaa cttgcgcaat gatgaaagga acgacaagat tccaactaat tgcccctgtc
    12121 atcgccatag ctagagagac tgcaggattc aaatgagctg ggcccatgaa tccagaaata
    12181 tagacagcca ttgttacagc gagtccccaa ccaaatgcga tgacaatcca gccagaagcc
    12241 tgtgctttac ttttgtttaa attcacagcc gcacacacac catctccaag caaaactagg
    12301 atcagtgtcc caataaactc ccccatgatt tgagtcatat cactgttcat ttatttctcc
    12361 ccctttagtt cccgcagatc tgattctgca atcaatgctt ctaaacgttt agtctgttgc
    12421 gccttctcct cttctgtcca ttcaaaatat ccagcaattg catcgatcac aggttgcttg
    12481 atctcatcaa gctgatctcg ttcaaacaac agatgatttg tacgacgaat gagataatcg
    12541 cctggggcca aaaccatttc ttcttctaaa ccataacgta accgagctga ctcagcgaga
    12601 ctcaaaccag gataaggtgc catttctttt gctaattcaa agatacgtcg ggcattagtc
    12661 ccgtaaaaat cagcgatata agtagcatct tcttcctcta aaccggctgc tactccttct
    12721 tttgctaatt ctgtcactgt ttcttctaat ttagttggat cgaagtttcc acctgaaatc
    12781 tgatattttt tagagtcgat ttctttcgtc tctattccgt attcttcttt taataattgg
    12841 cgtatcaatc gcaaagctcc ttctgccatc ttacggtaat cggtgatttt cccaccagat
    12901 aaagtcagca aaccatctgg ttctctttct aaagaactac ctctggaaat cgtagaaggt
    12961 gctttttcat cacggctgtt ttccaaatgg ttcaacacgt cttctacttc agcacgagaa
    13021 actttgtttt ccttatattc acttactgta tcgacaactt tattgaagct cttgtctgaa
    13081 atcgatccat tatctccacc attgtaatca gaaccagaat taccaatcaa cagtggacga
    13141 agtcctgccc agcttgcttc gatatcattc aatgtgatat ttgcttctgg atagcgatga
    13201 ttgatcacat ccaatagata atctacatct tcttgtgtga ctttcggatc cgtaaaatct
    13261 ccttggtaat ccgtatctgt cgtaccaaag taagtcttgt tttctcttgg aatagcaaaa
    13321 accatccgcc catcttgctt tcctgtatcg aagtatgtgg gttgcggtac aggcagtttt
    13381 ttcgcatcta caactaaatg gatcccttta gttggacgca ttttaggaga gactggacgc
    13441 gtaaaattca agtttcgtac tttatctacc caaggaccac tcgtattgat cactaatttt
    13501 gctttgattt cgatcacttc atctgtcagc aggtcacgag ctttgacgcc aacgatttga
    13561 tcgccatcat ataaaaagcc aaccgctttc attttactta ctagataagc cccatcttcg
    13621 gcagcctttt tgatattatc aatcactaaa cgggcatcat tgttgcggaa atctagatag
    13681 acacccgcgc cttttagccc ttcttttttc aaaaacggtt ctctttccaa tacttcttct
    13741 ggtatcagcg tataattctc atatttggtt cctgtcacat ttgccagttt gtcataaagg
    13801 tccattgcta ctttgaccga gaacatattg aaggttgttg ctccttcgcc ctcatagatt
    13861 ggcaaaagca ttggatctgg ttttgggatg tgtggggcaa tactttgtac gactgcacgt
    13921 tcaccaactg tgtcagctac tacttccaca tcaaatgtct tcagataacg aataccgcca
    13981 tgaacaagtt tggtcgagcg agaggaagtc ccttctgcaa aatcctgcat ttcgatcaat
    14041 cctgttttga ttcctgatgc tgctgactgg actgccacac cggcaccagt gattccgcca
    14101 ccgatgatca acagatccaa ttcttcttgc tgcatttttt gaatgctatc ttgtcttgtc
    14161 ttgtttgaaa acatatggat ttcctcctta ttcaaatgct tgggtagctt ttactgcttt
    14221 tttccaaccg ttgtaaagtt tttctcggcg ctcttcctcc atttgaactt caaatagctt
    14281 gccagcttca taaaattcgc ggatctcgtc tgtatctttc caataaccga cagctaatcc
    14341 tgctaaaaat gctgccccta gcgccgttgt ttccaagttt tctgctcgtt ggatcggtac
    14401 attcaagata tctgtttgga attgcatcag atattcattg tttgctgcac cgccatctac
    14461 tttcaataca ggaatcttga ttccagtgtc atcttgcatc gtatcgatga tatctctcac
    14521 ttgataagca atcgactgta aagtagcttt aatgatatct tcttttgtcg taccacgtgt
    14581 caagccaaac atagcccctc gtgctgcctg atcccaataa ggagcaccta gcccaacgaa
    14641 tgcaggaaca acataaacct catcttcgct tgtagagcgt ttcgctgcgt cttctgaatc
    14701 gctagctttt tgcaacattt gaagtccatc tctcagccat tgaatcgaag aaccagccac
    14761 aaaaatactt ccttctaaag catagtaaac ctttccattt atgccgtaac caattgtcgt
    14821 caataaatta tttttggata attgcggttt ttcaccggta ttcatgacaa taaatgaacc
    14881 tgtaccataa gtattcttga ccatgcctgg ttcgaatgcc atttgtccga ataatgcggc
    14941 ttgctggtct cctgccatcc ctgaaattgg tgcttcgctt ccataaaaat gataaccttg
    15001 cgtataacca taaacttctg agttagaagt gacttttggt aacatcactc gaggaatatt
    15061 tagtaaatct aaaatctcct gatcccaatc tagctgatgg atattgaaca acatcgtccg
    15121 actggcattc gagtaatcag taacatgtgc ttgtccatcg gtcagtttcc atactaacca
    15181 agaatcgatc gttccaaaca tcaattcgcc tttttcagct cgttcttgcg cgccttctac
    15241 atgatcaaga atccagcgta tcttcgttgc tgagaaatag gcatcgatca ctaaccctgt
    15301 tttttcgtgg aaaaattctt gatagccttc attttttaag ttatctgcaa ttccagctga
    15361 ctgtctggat tgccaaacaa ctgcatgata gattggacgt cctgtatctt tttcccatat
    15421 tactgttgtt tcacgctggt tcgttatgcc aatcccagca atctgatttg gtttgatccc
    15481 tgattcgatg aacgctccgg caataactga ctgtacagaa ttccagattt catttgcatc
    15541 atgttccacc caactttctt gcgggaaata ttgcgtgaac tctttttgag aactgccgat
    15601 gtgtcttcct ttcttgtcaa agataattgc tcgtgagcta gttgtacctt ggtcaatcgc
    15661 catgatatac gttgattctg tcattgtgat tccctccatt atatgcaaac gctttcttta
    15721 actactctta tcatactact gttttaaaaa aagaaactgt caaaatttta ttcttttttt
    15781 ctttttttga cagtttttta ttatgaagct attttttaat caattctttt cttttttcag
    15841 cgtctctatt cttcttttca atcgaataat gtcgtaaggt gacgcaaatt ctgacagata
    15901 atattcacac tgttttttgt ttctctggca aaatgtgatc accaaatcat attctttacc
    15961 ttcttcataa cttccaatct caataccgcc gattcccctc agttctctga tcagatattg
    16021 ttgaaaagca atacgataaa tcggcagact ttctaaatcg attccaatca ctactggttt
    16081 tgcaatataa aaatcgatca tcaaaagaac attggcatac tggatcatca ggtaactaag
    16141 ctcactatct tcagctcttt tcctcggcaa ttgctgcacc gctgtttcct gtaatttcgc
    16201 cagtaactgt gttaaggaat gcccgagcat tttctgctgc tgttccaaaa gccgatcacg
    16261 ctcatagact tcgatctttc caacaaagaa aaaccattca ttgttgatct gggaaatttg
    16321 gtagcctact gccttttctt ctttgatttt caaacgacga ggacgataat gccataacat
    16381 cgtttcccga atgtaagtat ctaaaacagc ggttggtaac tttttgctcc gtgtcaaatc
    16441 atactgataa aatatttctt cgtctactat cgaaaaagaa acaaaaaagc tgtaaaacat
    16501 cattgtttcg tatacattca gttctgctgc tgttcgacta agatgcatca cgatgattgg
    16561 atcgattgct tgataaagcc ggtccgactg atagagtaat ttcttttctt tcaaagttgc
    16621 gtacgtactt ttttcattca atagtctttt tttcgtaatc ccgagccagc aagcaatctg
    16681 tgcttctgct gatgccgtaa acgttgtttc taatacacgg tccaatccta gaatgaacgg
    16741 tcttttttct ggtgtatttt gcaaaaaaag cggtcgctga tcttccggga tatattggaa
    16801 tagttcataa taaaaatatc gtatctgtag ctcttctccg tataattgac cgtttttgat
    16861 ttgtaatcca aattcctcta agagctggtt caattctttg atctttcgaa aaacagaaga
    16921 ctcactgata ttaaacgctg tcgctaatcg aacgatggat acttgctgat gttctaataa
    16981 atagacgagc atcttaaact ttaagctttc ctgcaataaa aacaatagaa ttttttccaa
    17041 acttacatct tcgtccaaca caagcagcgc ctgatactca tttcgctgta cttctacttt
    17101 tttttccatc attcggccaa tcaattcaat atcttccaaa tattgatcaa acgaggcttt
    17161 tgacagttgg acatgctctc tcaaaccatt gatagaggct gttccccctt gcagaacaag
    17221 gtttcgcaaa atcaggatct gtaactgctc ttttctttct aataatgctt caatcttcat
    17281 aggcagtatt cgccaccttt gaccacacca tatctggcac acggtattct ggctggaaaa
    17341 atagctcatg ttcttctaac tgttcaaacg tccatccttc ttttactgca attgtcagtt
    17401 ggtcaagaag gtggaacatc tcttttttgc tttggagctg tgctccaaga atcttttttt
    17461 cagaatcaaa tagaaatttg agtttaactt tgctttgatt tattgctgta agcttgtagt
    17521 ctacgtatcc tgtttcaatt ttttggggat aaaaaatgct ctcttcttct gtcaaaccta
    17581 cgcttcctaa gaaatagcca aaccactgat tgccgactgg acgataggtt ccctgatcct
    17641 ttgtctgtga gccactaatt gtcttgctga catttcgtgc tgtacggaca gcgttattta
    17701 ctagagaaac atacattttt tcatttgttg gacgaaaagt tacttggatc gcatcgccaa
    17761 tcgcataaac gtctttttga gacgtttgca agtagtcatc tacccagatc gttccatcat
    17821 cattcaatgt taattgttct tcccacatct gattgtcggg gcgagaatga ttagccagca
    17881 aaacaagatc atagttctcc tttctttttt ccgtctctac aatagcggtt tcattttcgg
    17941 tcaaagacac aacttgttct tctaaaaaaa gtgaaagccc ttgatttttc atttccttta
    18001 ctaacggttc tgtcatttca ggatctagat aacgaaaaag aattgacttt cggctttcgt
    18061 aaagatggat ttgttttttt cttgatgcca acccttcagc tatttcgatt cctgcttgtc
    18121 ctgcaccaat aattgcaatt ttctttgcat tcatgatctt ttgctgaaga gccgttacgt
    18181 tttgtatctt tttaactggg tgaataagcg ttgattctgc agaaatattt cgaaactttt
    18241 gatttgaacc agtcgctaga atcaaacgat caaaatccaa tttttttcct cctgctaaaa
    18301 cgactttttt ttctttcaat cctattactg tcttttctgt gtaaacatgg attcgatagc
    18361 ggtcagtcag ttcttctttc gtgatccaag aaagttgttt ttcactggta acctttcctt
    18421 ttaatatcaa attgaacccg ctgggaatcc atcctaactt cgattgcttt tcaatcaaat
    18481 atatttcact tgttggcatc aattggcgaa gataaatagc cgcatgaatc cctgcaaacg
    18541 acccgccgac aattacaatg ttcatctgca ttcctctttc ttataaggtg ttctactgct
    18601 aacttctcaa tcagaaaaca cagtattcat aactcgcttt caaccttatg atacatagcg
    18661 atgcagcaga atcaaccctc tccatcatac cgtgttctag gtctgcttct caataatgta
    18721 ctagtggacc taattgaaga gtatcatttc tgaagagatg tttcaaaaaa tgtactctta
    18781 taaaagaaaa aaactcgcct tttacgtacc tctgtccaaa taggaaacag aaaagaacga
    18841 aaagacgagt tttagcgtgt gtaatgtaat agttagaata gacacatcat ttatttttaa
    18901 ttctttaatg cttcaacaac tgcttcgcct aattgatgag cagattgagg attttgccct
    18961 gtaagaagcc gcccatcaat ttgaaccact tctgaaaaag ctgctccaga ctgatagttt
    19021 gctccttttt ctttcaaagc atcttctgct aagaatggta cttcattcgt tgtaccattt
    19081 gcttcctctt cttcattact gaacccagtc actgtacgtc cagctaaaat agattttcca
    19141 gactcatctg taactggcaa caatcctaca acaccgtgac aaacagctga gaccagccct
    19201 tcatttcgat agatttgtga agcgactttc ccaagatcta ttgcttctgg aaaatcccac
    19261 attgttccgt ggccaccagc ataataaacc gctgcataat catttgcatc cacatcatca
    19321 ggacgtaagg tatttcccaa ggcccgattt ctgaaatctt catcttcata ataggcccaa
    19381 tcgatttcat ccatattcaa aacactttgc ggttctaaag gtacatatcc gcctttagga
    19441 ctgacaaaat ctgcatcgat cccatttttt actaatacat cataaaaatg agtcagttca
    19501 cttaaccaca aacctgtagg acgctcgatc ttttcgtact tttctacatt tgttaatacg
    19561 atcaatactt tcattttccc atcctctttc tataaaaatt gcgttattga taacgtgctt
    19621 tcaagaaatt atataatggg cttggcaaat aaagctcttt atatgcttct tcaaaaggtt
    19681 tcgttacaaa ttcatcctca cggttttcca ataatttctc tgcccagtca ggatcgacga
    19741 tcatttgctg tccaattgct gcaagttctg catatttcaa tacctgctct acatcttcgc
    19801 gattgcggat cccaccgaca ccaactaaag ggatctttcc ttgaatcgtg ttatggacca
    19861 cttcaagaat cgatttatcg ttgtatttat cagaacgagc tattcgatca tacatattta
    19921 atgaaacatg cagataatct agttttgact cacgtaatcg ttcaagaagc cagatcgtgt
    19981 cttcaaaacg gatacctggt gtttcatatt cttctggtga gaaacgatac cctacgatga
    20041 atggtttttt agcatattgt tcaaccgctg agaaaaccgt tgttaataat tcttcaataa
    20101 aacgataacg attttccaag ctaccgcccc attgatcctc tcgtctattc gaatgcggag
    20161 agaaaaattg ttggatcaaa tacgtatttg ctccatgcaa ctcgattcca tcaaatcctg
    20221 attcaatcgc tctacgtgtg gctttgccaa atgcttggat tgtttcaacg atttcttctt
    20281 cactcattgc tcgtggtgtt tccgcatcag gacgttttgc tgcaactgca cttgcagata
    20341 caggctgttc tccagataaa gttgctcgac ttgtcattcg tccaccgtgg aaaatctgaa
    20401 taatcgcttt tgcgccttct ccttggattg ctttcgctag ctcacttaat cgaggaatca
    20461 tttcatcatg agcgatgctg agttcacctg gccagccttt tccgatatct tggacatttg
    20521 cagcaccagt aataacagca ccaagacctt tagaacgttg tttataataa gtgatctcat
    20581 cttcggtgat cactccattg aaaaagctga gttgtgtcgt cataggcgac agcatcaatc
    20641 ggttcttcaa ttgaactcct gaaggtaaag taattgattg atcaaattgt gacattgtca
    20701 ttcctcccat aattcgctct gattaaccta tcgagaatca tctatcatta aaccactcga
    20761 ttagttgtac atgcaactaa tttgcttaaa aaattttatt ttttttgtaa cttatctgtt
    20821 gcatcattca ttgtctgggc taattcttta cttgcttcat ttcccaaaac tgctttgtat
    20881 gactgatgaa gttcttccca gctaccatcg acttccttag caaattggcg tccttgttct
    20941 gtaagataaa ctaatgacaa gcgaccttcg ctaactgttt tgacgtatcc tttatattct
    21001 aatttttcaa caaaacgagc aatcgttgat ggggcggaat agagcatttg tgcaatatct
    21061 ttttgtggta ttccatcttt ttcttttaat atcaataaaa taaaaccata agttggtgcc
    21121 agacctgtcc ttctaaacgc ttcatcagct aatttattca acatgcgatc tagctttttc
    21181 acgctaaaga aaagacattc atctaacgct ttttcaattg gcttttccat ttcatcccct
    21241 ccattggcgt acatatcata gtatgatttt tattttttgt caaaaaacac ggaataatgt
    21301 ccgcctcctc tgtctagatt tgaaaaaaag aagtagccat cttcaaagaa tttcggcttg
    21361 ttttcgacaa aactccttct ggaacaccgt gaatcagagg ttgtgaaaaa gtcgtttagt
    21421 tttgagtatg aagaaaaatt ttgtgaaaat ggctttccac atttttgcat aaatttggct
    21481 taataccgaa aaactggctt ttgaacaccg tttatatcag aggttgtgaa aaagccgtcc
    21541 tgcatcaagt aataagaaca gccaaacaaa aatagttcct catattttgt cgttttttga
    21601 gctaatgccg atggtcagct gattgtacac cgtttattga gaggtcgtga gcctgccgtt
    21661 gaactccgag tcacaaggag caatttcaaa aaacagcttc tcatgtttta tgactatggt
    21721 gacttgtgat cgaggagttg gcaggagaat actgtttatt cgtaaagaag gggctgtgac
    21781 aagacttttg tcacagtccc ttatttcctt ttattatagg atttcgccat ttgattggat
    21841 gacttgtctg taccaatcaa atgatttttt ctttaaccgt ttctttgtgc cattcccttc
    21901 gtcatcttga tcaacataga tatatccata acgttttgac atttgtgaag tagaagcgct
    21961 gacgatatca atgcagcccc acgacgtata accaaataaa tctactccat cttcgatagc
    22021 ttccttcatc tgctcaatat gctgcttcaa atagtcaatg cggtaatcgt cttgaacggt
    22081 tccatcttct tctactttgt ctatagctcc gagtccgttt tcagctatga acagtggttt
    22141 ttgataccta tcatataatt gattcaaagc aattctcaaa cccttaggat caatctgcca
    22201 gccccattca cttgatggaa gatacggatt tttaattcct ccagttatta agtttccttg
    22261 gaccccttcc aaattttctg gatgagcact gactgcacta gacatgtagt agctaaaaga
    22321 aacaaaatca acagggtagg ctgctaagat ttcttcatca cctacttcta tttttaagtt
    22381 gacacctttt tcttcaaaca ttcgttgcgt atacgctgga taatatcctc ttgcttgaac
    22441 atcactaaag aacaaagaag ttctttgctg ctcaattgtt ttttgaatat catccggatc
    22501 acaagaatac ggaacaagaa gctgatagct gatcatacaa ccgacttgtg aacctttgat
    22561 aatttcatga caagcttttg tagctaaagc acttgctata aactgatggt gtgcaccttg
    22621 gtatttcgct tgttccaaat ggggatggtt ttcttcaatt actcctacgc taacaaaagg
    22681 gtgatgtttt acacagttga tctcattgaa agtcatccaa tattttactt tatttttata
    22741 gcgtttgaat actgtttcag cgaaacgaac gtaaaactga ataagctttc gattaggcca
    22801 tccaccatat tctgtaacca aatataacgg catttcataa tgggaaagag aaacgactgg
    22861 ctcaatccca tattttagac attcgtcaaa cacttgatca taaaaaaata atcccgcttc
    22921 attgggtgtt tcttcatcac catgaggaaa aattcttgtc catgcgatag acatccgata
    22981 gcatttaaaa cccatttcag caaataaacg gatgtcttct ttaaagtgat gatagaaatc
    23041 atttccgtgt cttttaggat aataatactt gctgttggga tcctgcgccg cttttacttg
    23101 ctgatgcgtc atcatatgcc attgatctgt ccatttttct ttaggtaaat cgctgtcgaa
    23161 tgtatacaca tcagacacag ataatccttt ttcatctaca tcccatgcac cttcacattg
    23221 attggccgct gtcgctccgc cccataaaaa tccttctgga aattttttca tatcgatccc
    23281 cctaaacttg ctagttttct tgtttgatta tttttcttat gactagtaat gatatttttg
    23341 aatctactac tatttgtaac aataaccatt gtggtcggat catatccctc tttgattaat
    23401 tcttgcaaat ctacttccat caataaatcg cctttacgta ctttttttcc atcagatact
    23461 gcactttgaa agtatttgcc atttaaattc actgtatcaa taccgatatg gatcagtatc
    23521 tctgctcctt cttcactgac taccccaatt gcatgtttcg ttggaaaaac tgttgaaact
    23581 tccccgttta caggactgta gatttttccg tccgttggaa tgatcgcaaa cccttctcct
    23641 aaagatccac tagcaaatgt tggatcgttt acttcagata aatcaattat ttcacctgct
    23701 gcaggagtac ttaacactat atcctttgag gattcttctt cgatttcatc cttgtagccg
    23761 aaaagaaaag ttagcataca ggaactgatc atcgctaaga aataactagc aactagccaa
    23821 acaaatcctt caccaatata aatcgggaaa gacaaaatac ttcttgtagc aactgccaaa
    23881 gcaccggctc ctgcggcacc agctactcca ccaaatatag ctccacatat acaagcaatg
    23941 taaaatggtc gtttatattt aagagtcaca ccataaacag caggttcagt gattccaaat
    24001 aatgctgtga taaatgcaga taaagataaa ctttttactt tcttattttt cgttttcaaa
    24061 aataccccaa gtactgctcc tgcttgcgca gctacggcag tcatacatgc tggacctagc
    24121 gtatcacgac cgtagaaaga aagattgttg gtcattactg gtacaagtcc ccaatgtaac
    24181 ccaaaaatca ctaacacttg ccaaaatccg ccgataacag caccagataa aacagggcta
    24241 aagttataaa cagctaaata tccagctgca atcagctgac ttgcataatc tgcaattgga
    24301 cctacaacta ataaagtaat tgggaccatc acgatgatac aaatgaatgg tgtcaataaa
    24361 tttcgaatac tttcgtgcaa gcttttgcga atcttaggct caatataaga aagaacccat
    24421 acagctaaaa ttgctggaat aaccgtactt gtatatcttg ctagaatcac gggcatccct
    24481 agaaatcgca aggttatgct atcactatat gcactgacaa tcgtaggata aacgagagct
    24541 gctgcaataa ccatagcgat gaaacgatct gtattgaact tttttgcagc agtatatgcc
    24601 aaaaatatag gcaagaaata gaaaaatgca tcagctgctg cattcaaaat gatataagtt
    24661 cctgattcag tagttaataa attcaaactc gtacataagg cgagtactcc tttgatcaaa
    24721 ccacttcctg ccaagacgcc taaagtcggg gcaaaaacag cggcgatcat gtctataaaa
    24781 gagtttaaaa tgcctttttt ctcagttcct ctctttccac tagatgcatc atcttctagt
    24841 ttcatttgtt tggataatac gtcatacact tcatttactg catttcctac tacgacttga
    24901 aacattcctc cagcttcgac tacagtgatc acaccttcta gttgctctac cttctcctta
    24961 tctgccttct tattatcttt tagggtaaag cgtaaccttg ttgcacaatg gtaaacattg
    25021 ctgacatttt cttcgcctcc gacaaatcgg acaatatctt tcgctaattg tgaatagtcc
    25081 atttttactt cccccttgtt aattaatgcc gtagcaatcc ttcttacaag ataagtatag
    25141 ttcttagaaa acggtttctc cattcaatta gtaccccttc taatagcgaa cgaaactgta
    25201 caatagtgtg tatggtttac ttagccgagc aaatcactca ctgcttgaaa gaaaacaagt
    25261 atatcgtttc tcttatagtc aaaggagaca aaaaaaacac gcttgatctt cctttgctga
    25321 tgtataagtg gtatctcaag ctgatactct gtgatttttg tttctacttg gcttttgata
    25381 agacagcaca acaaagtctc ggcatttaac ggaagcataa ctaggtcaga actaggagag
    25441 attagttgct gaatggaatc tatcttttta tggattttta tttgattttc ttctttgtag
    25501 taatgatcaa gcagttttgt tttctttttt tcttcaacta tggtcagctt ttcacgcaaa
    25561 atctgataaa tctccgaaga ttcaaactca tctagaacac taggtagata aatcaaatca
    25621 tcccactcaa aaataagctc ttgctcagta gtcaaaattg catcatattc cgttattttg
    25681 tttgattgat ttttgaaaag atacactggt tctatccggc attctttgat ccacatgttc
    25741 atactttgtt gaatctgttt ttttagtgta ttcaaaatac taattggctg gttactaaca
    25801 atcagtatct ccccttgttt tcgaaaagga ttcaacgctt cggcaagata caaaaccaaa
    25861 taagcgcttt cagctaaatt gggacgtaat tgaaaatgta ttgggaagaa acgccgaatt
    25921 aaataaattt ctaaaggata acgggagatg atcttttgta caaaatgatt catggtatta
    25981 tgtccggcat ccatcctcgt tttcatttgt ttgatatggg ttagcaaaaa ttctgtttca
    26041 tggaacaata acgaaacagg aagatctaaa aaacgaataa tcgtttgctc aaatgctctt
    26101 agattcttct ctatttcttt gtttttttca tcattaatca tcaaataatt taactctaat
    26161 agtcgatttt caattgcttg tttttcttga ttggaaaaag aatagggtag ttctgatgat
    26221 aacttttttg tgagggtctc taccatcgga ataaataatg tatacctgtt tgttttttct
    26281 aaaagttctt ctcttcgaag aatggtcaaa acgagatacc gagaaaatcg tatgaagtcc
    26341 tctcctgaaa caatataatt atatgatata agaacctctt ttaatgtctt ttggacagtc
    26401 ggcatgatat tggaaaaaat tgtactgatt tgttgaggca accttgcgtg ttggatcacc
    26461 gtttctgttc caacaagaga taagaaaatt ctttttgaat tttcttcagc aatgattttt
    26521 agtccttttg tcgacgaaac ttccagttct aatttaggat tgcgctcgat ccaacgcaaa
    26581 atcgttttta tttgtaatga tacggctgtt tttgaaagaa agaaaatgtc tgctatcttt
    26641 tgcatactga catacccttt ttgaaacaat aagtacgtca caatagttga agctcggaaa
    26701 tccatgctgg aatagatttt atgtttcgtc acctcttgta tgatttgctg tttagtttca
    26761 gattcaattg attctaaaaa ataacctgaa cgtttatttg actggataat gattttcttc
    26821 tcgtagatag caagcatatt tttgatttca gtttggatcg ttttcttgtt ggtacctaaa
    26881 gcttcagcta attcttcgct tgttatccaa tgattcttat ttcttaatac tacaagaatt
    26941 tggagttgtc gtttatttaa gtccatttgc ttacacctcc tctttgttat aaacatacag
    27001 gaaaaacctc tcaaatgaca atagtcactt gcagaggttt aaaaatcatt tgaagaaaga
    27061 tctatattca aggtttttac cattagactg gataatttgt ttataatatt caaaactatc
    27121 ttttttcaat ctcctaaagc ttccgctccc atcattttgt ctatccacat aaataaagcc
    27181 atatcgcttc ctcatttccc ctgttcctgc cgatacgata tcgattggtc cccaccataa
    27241 gtaaccaatg atttggcaac catcttttat tgcctcagca atttcctgaa gatgtatttt
    27301 tagatactca caacgttttg gatcgtggat tcgattcaat tcatctggtg cttcatctag
    27361 tccaatgcca ttttcaacta tgaataatgg taattcataa cggtctgtca attcattcat
    27421 gacataacga aaccctagag gatcaattgg ccaactccaa ggttcgggag atttttcctt
    27481 caaaaaggga ttatcgaaac catttgctcc gccagtatct acgcgcattt ctgcttcttt
    27541 tttatagaca gcgctacgat aataactaaa tgcaatataa tctaccgtgt tagcttgcaa
    27601 gtactgttcg tctccatcta acattactgg tgcacagtct tcttccttcc atatcctgta
    27661 aatataagct ggataatgcc ctcggcacat gacatcggag aaaaaccatg aattgcgttt
    27721 aaattgcagt gaaccaaata cattctctgg atcacagtca tatgcataag tcgctaatgc
    27781 agaaaagcta cacataatac ccatcttagc atttggatcg attttcttta ataattgagt
    27841 agcacgggcg ttcgctagaa acatatgatg acaggcttga taaatctctt tttttgttag
    27901 tgtagcaatg ggttcaagtt tatctctagc agggaatgta accaatccag cagctgcata
    27961 aggcatacga aaagcattat tgatctcatt aaaggtcatc caatatttca ctttcccttg
    28021 gtagcgttca aagacggtct gcgcataaaa ttcaaaaaag tcgattaatt ttcgattttg
    28081 ccacccccca tactctccta ccaatgctaa gggggtttca taatgactaa gagtaattac
    28141 tggctcgata tcatatcgat ttaatgtatt gattagtctg tcataaaata cgagaccagc
    28201 ctcatttggc ttctgttcgt ctcctcttgg aaatattcgt gcccatgaga tgcttgttcg
    28261 aaaagctttt aaacctaact ccttcagtaa acgaatatcc tcttcaaatc gatgataaaa
    28321 atcaatcgct tcatgagaaa gataatggag tgattcgtct aaagcaatct cccaaatctt
    28381 tttttcttca ttccactgaa tactaggatg ctggttcatg atcccgataa gcgtatctgt
    28441 cacattaggt aatttgccgt cttccaacca tgcaccttca cattgattag cagctactgc
    28501 tccgccccat aaaaaatttt ctggaaatat ttcctgatcc ataactatct ctcctcgcta
    28561 tcaacaattt cttacttgaa gtatagctcg attcatcaaa acaagatatt ctaactattt
    28621 cggcagaaga gaagaaaaaa attgaatgct actcttcatt tttaatattt atatataaca
    28681 aatacataag acgatccccg aaagaaaaca ctcgttaacc atctaagcaa acgatttatt
    28741 ttacttccaa cacaaatgct tcataaggtc gtaaatcaac tttgccgtct ggtaactgtt
    28801 tcagaggata atttgacaca ataaccctta aagcttcacg tggaacagtg aacgtctgct
    28861 tttcactgga catattacaa ataacgagcc attgctggtc ttcatatatg cgagaatagg
    28921 caaagacatg ctcaggcgtc ttttccacta attcatagtc tccccagacg atgatgtcat
    28981 gttttctacg caaatcgatc aatttcttgt acatataaaa aacagaatct tgatctgcta
    29041 acgcttcttc tgcattgatt tctttataat ttggattgac tcgaagccat ggaattccag
    29101 tagtaaaccc agcatgttca cgggcgttcc attgcatagg cgtcctagca ttgtctcttc
    29161 ctttcgcatt gattgattcc aagatttcct cttttgtaaa tccagaagaa atcctttcgt
    29221 tatacatatt gattgtctca atatcttttg cttccgcgat atcatcgatt gggcaattcg
    29281 tcatgcctaa ctcttctcct tgatagatat aaggggtgcc tttcatcata tggagcaaga
    29341 tagcaaacat cttggcactt tcttttcgat acacatcgtc atttccccaa cgagaaacaa
    29401 ttcgcggaag atcgtgatta ttccaaaata aactattcca tccttcatca cctaaagatg
    29461 tttgccattt ggataatact tttttcagtt cagagatact caagggtttc aaatcccatt
    29521 tgtctttgcc ttcttgctga tctaatccta tgtgttcgaa ttggaagacc atggataatt
    29581 catttctttt aggattggaa taaagtttag cgatttcggt agttgctccc catgtttcgc
    29641 caacagtcat cagatttttg tcaccaaaag ttgcttgatt catttcctga agatactcat
    29701 gcagtttagg tccattactt gtgatttctt tatccggttc tttgccaatc atatcgatca
    29761 cgtccatacg aaagccacca atacctttat cgatccagaa attcatcatt tgataaatct
    29821 cttggcgaac ctgtttattt ttccaattca aatcaggttg acgcttgcta tacaagtgca
    29881 gaaaatattg ccccgttttt tcatccaact gccaagcaga accactgaat attgagcgca
    29941 atctattagg ctcttttcca ttgaccggat cacgccaaat ataatagtcc cgataaggat
    30001 tttctttatt tttacgggcc tcaatgaacc acggatgttc atcagaagta tgattcacca
    30061 ccagatccat gatgatacgg atatttcttt tctttgcttc ttcaatcagt tcttccattt
    30121 cttccatcgt accgaattct gccatgattg cttgataatt actgatatca tacccattgt
    30181 catcattcgg agactcgtat actggagaaa gccaaattgc atcaatacct aaatacgcca
    30241 gataatccaa cctggaaata atcccccgca aatctccaat accatcttga tttgaatctt
    30301 gaaaacttct tggatagatt tgataaacaa ctgaatggtg ccaccatttt tgttccatga
    30361 ttttcctcct ataaatggat gtttctattt tttgcttaat catttatttt agtctctctc
    30421 actaaaaatt gtaacgcttt caaatagcta ttgcaccttg ttatcggtaa cagaataaaa
    30481 caaaaaaaca gctgaggaaa ttccctcaac tgttttttga aaggattgat ttattcaggg
    30541 aagaatgctg atttcacaac ttctttataa acggtgttca ctcagctgtc cctcggtatt
    30601 agctcaaaaa acggcaaaat ataagaaact atttttttcg tttttttctc taatactcag
    30661 gccagaacac tgatttcaca acctctttat aaacggtgtt cactcagctg tcccttggta
    30721 ttagctcaaa aaacggcaaa atatgaggaa ctattttttc gtttttttct ctaatactca
    30781 ggccagaaca ctgatttcac aacctcttta tttcacattc aatatccaca tgaatcccat
    30841 gaatacaaag aacagaccat acatgatggg agatacttct tttcctcttt tagctgctaa
    30901 catggtaatt ggatagaaga taaaacctaa tgcaatccca tctgaaatac tataagtcaa
    30961 aggcatgccg atcaagatca agaatgaagg gatcgcaatc tctaagtttc cccattcgat
    31021 ttgtcgcaaa gattgtgcca tcaatactcc taccataatc aatgctggtg cagttacttg
    31081 tgaagtaaca actgatagta atggagaaaa gaacaagcct aacaagaaga aaatccctgt
    31141 agtaatagct gtgatacctg aacgtcctcc aacggcgata ccagctgatg attctacaaa
    31201 tgcaccaaca ggagaagtac ctaataagga acccgcaagc atagctgttg aatcagaagc
    31261 taaagctttc cctacacgag gcatcttgtt gtctttcatg aaacctgctt ggtttgctaa
    31321 tccaactaaa gttcctgctg tatcaaagaa agtcacaagc aagaatgtca gcactacgac
    31381 ccacatttga agagaattga tgtcccctac atgttttaat gcaactaaaa atgttggttt
    31441 caaacttggt gctgcggcaa caatttcaga aggcattgga atcaaacctg tgaccagacc
    31501 taaaatcgtt gtagctgcca tcccgatgaa gatgccacct ggtacacgcc gaacaagcaa
    31561 gatagcagtt acgactaatc caaaaatcgt caaccaagta gaaccaacgt tgagtgatcc
    31621 taatcctact aatgtagatt cattcgaaac gatgatccca ccttcgctca gaccaaggaa
    31681 agcaataaat agaccgatac cgccagaaat cgcatatttc aaatctgctg ggatcgcatc
    31741 aatgatcatt tcccgcagct tgaagattgt gatcaaaata aaaatcaaag aagcaacgaa
    31801 tacgccggct aatgctgttt cccatggaat ccccattcct aaacaaacag aataagcaaa
    31861 aaaagcattg atcccaagag caggtgccgt tccaattgga taacgggcta atacccccat
    31921 taaaatacag ccgatcgcac tggctaatgc agtcgcagta aacactgctc cttcatccat
    31981 tccagaagca cctaatacag ttggatttac aaataagata taagccattg agataaatgt
    32041 tgtaaatcct gccagtacct cacgttttac cgtggtgttc aatttttcta tttcgaagta
    32101 ggaaagtatt ttttccttca tcttccatcc ccctaaatcc gaacattata aataaagtcc
    32161 gttaaaattt cgatttatta ataaaacaac gtgttttatc atatactaaa acaaaacata
    32221 agtaaacaaa aaattcggat tttaagcaaa atccgaacgt tccatctgat taaatccctt
    32281 tatctcaaag ttcatgaaca ttcactttgg attacaagaa tttctttatt gtgttaataa
    32341 agtttcttca ttctagtctc aaaaatcaat agtgtgattt gattttacca tttcgtttct
    32401 gttcttcttt gatgaattct tttgtatcga caggattcag attatttagt ccgccaaaac
    32461 ctgtatcgac catttttccc cagccttttg tcttcttttt tcctgatttg agattctttg
    32521 ctcgaagctt ctcactatgt tttgctcgcc gatacttcaa ataaccttct aatcttccca
    32581 ttagatccac tgtttctcct cctttttatt caatcagacg actcagcttt tcctataaca
    32641 aaataattgc cttcagggtc cgaaaaattg aaagtcaaga cgccattgtt gtctgtgatt
    32701 tctcctggtt cttccatgtt ctcgtagata gtttcaaatt catccgtaaa aaatactaaa
    32761 gaaggcggtg gtcctaatac ctctggtgaa aacttctgca caaatacttt tgggaatacg
    32821 cctaattcta attcttttga gatgctgagt acaatactct taaattcttc tggcaattcg
    32881 attgtttcag aaatttctgc accaattttt tctacaaaga atcggcaaat catctctacg
    32941 tcattgacat aaagcatcac acgtgttttt tgtatcatcg tttgaccctt ctttctattt
    33001 gattttcttt cctgtctata aactgattcc attatatcac gaaagcgcaa acaccttgtg
    33061 tttgatacta ttcaagaaaa ataaagcaat agtttctagg attgctttcc tccacaaact
    33121 tttttta
//
LOCUS       DAXLPY010000023        32534 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.023, whole genome shotgun sequence.
ACCESSION   DAXLPY010000023 DAXLPY010000000
VERSION     DAXLPY010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.023"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            132..506
                     /locus_tag="ACF3UF_001229"
     CDS             132..506
                     /locus_tag="ACF3UF_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFD3671373.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="ACF3UF_001230"
     CDS             complement(620..1249)
                     /locus_tag="ACF3UF_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3671374.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="ACF3UF_001231"
     tRNA            complement(1383..1455)
                     /locus_tag="ACF3UF_001231"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
     gene            1669..1742
                     /locus_tag="ACF3UF_001232"
     tRNA            1669..1742
                     /locus_tag="ACF3UF_001232"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1703..1705,aa:Asn,seq:gtt)
     gene            complement(1880..2044)
                     /locus_tag="ACF3UF_001233"
     CDS             complement(1880..2044)
                     /locus_tag="ACF3UF_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671375.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2339..3667
                     /locus_tag="ACF3UF_001234"
     CDS             2339..3667
                     /locus_tag="ACF3UF_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFD3671376.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3869..4702
                     /locus_tag="ACF3UF_001235"
     CDS             3869..4702
                     /locus_tag="ACF3UF_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFD3671377.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4718..5455
                     /locus_tag="ACF3UF_001236"
     CDS             4718..5455
                     /locus_tag="ACF3UF_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFD3671378.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5610..6578)
                     /locus_tag="ACF3UF_001237"
     CDS             complement(5610..6578)
                     /locus_tag="ACF3UF_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFD3671379.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6810..7643
                     /locus_tag="ACF3UF_001238"
     CDS             6810..7643
                     /locus_tag="ACF3UF_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFD3671380.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7677..8516
                     /locus_tag="ACF3UF_001239"
     CDS             7677..8516
                     /locus_tag="ACF3UF_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3671381.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8542..9102
                     /locus_tag="ACF3UF_001240"
     CDS             8542..9102
                     /locus_tag="ACF3UF_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3671382.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9301..11022
                     /locus_tag="ACF3UF_001241"
     CDS             9301..11022
                     /locus_tag="ACF3UF_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFD3671383.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11187..12329
                     /locus_tag="ACF3UF_001242"
     CDS             11187..12329
                     /locus_tag="ACF3UF_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFD3671384.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12345..13556
                     /gene="thiI"
                     /locus_tag="ACF3UF_001243"
     CDS             12345..13556
                     /gene="thiI"
                     /locus_tag="ACF3UF_001243"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFD3671385.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14129..14776
                     /locus_tag="ACF3UF_001244"
     CDS             14129..14776
                     /locus_tag="ACF3UF_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFD3671386.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14905..15121
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15169..17814
                     /locus_tag="ACF3UF_001245"
     CDS             15169..17814
                     /locus_tag="ACF3UF_001245"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFD3671387.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18124..19437
                     /locus_tag="ACF3UF_001246"
     CDS             18124..19437
                     /locus_tag="ACF3UF_001246"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFD3671388.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19427..20080
                     /locus_tag="ACF3UF_001247"
     CDS             19427..20080
                     /locus_tag="ACF3UF_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3671389.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20135..20827
                     /gene="radC"
                     /locus_tag="ACF3UF_001248"
     CDS             20135..20827
                     /gene="radC"
                     /locus_tag="ACF3UF_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFD3671390.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20977..21177
                     /locus_tag="ACF3UF_001249"
     CDS             20977..21177
                     /locus_tag="ACF3UF_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3671391.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21431..23110)
                     /locus_tag="ACF3UF_001250"
     CDS             complement(21431..23110)
                     /locus_tag="ACF3UF_001250"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFD3671392.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23112..23324)
                     /locus_tag="ACF3UF_001251"
     CDS             complement(23112..23324)
                     /locus_tag="ACF3UF_001251"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFD3671393.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23717..25447
                     /gene="efrA"
                     /locus_tag="ACF3UF_001252"
     CDS             23717..25447
                     /gene="efrA"
                     /locus_tag="ACF3UF_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFD3671394.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25444..27204
                     /gene="efrB"
                     /locus_tag="ACF3UF_001253"
     CDS             25444..27204
                     /gene="efrB"
                     /locus_tag="ACF3UF_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFD3671395.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27299..27496
                     /locus_tag="ACF3UF_001254"
     CDS             27299..27496
                     /locus_tag="ACF3UF_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671396.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27649..28134
                     /locus_tag="ACF3UF_001255"
     CDS             27649..28134
                     /locus_tag="ACF3UF_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFD3671397.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28238..28831)
                     /gene="clpP"
                     /locus_tag="ACF3UF_001256"
     CDS             complement(28238..28831)
                     /gene="clpP"
                     /locus_tag="ACF3UF_001256"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFD3671398.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29011..29532
                     /locus_tag="ACF3UF_001257"
     CDS             29011..29532
                     /locus_tag="ACF3UF_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671399.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDV"
     gene            29629..30366
                     /locus_tag="ACF3UF_001258"
     CDS             29629..30366
                     /locus_tag="ACF3UF_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFD3671400.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30370..31287
                     /gene="miaA"
                     /locus_tag="ACF3UF_001259"
     CDS             30370..31287
                     /gene="miaA"
                     /locus_tag="ACF3UF_001259"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFD3671401.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31289..32518
                     /gene="hflX"
                     /locus_tag="ACF3UF_001260"
     CDS             31289..32518
                     /gene="hflX"
                     /locus_tag="ACF3UF_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFD3671402.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVNRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEIAVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10772 a         5522 c         6874 g         9366 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tacttgattc cggcatagct
     1681 cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc ctactgccgg
     1741 agtaaataaa gcttatgcaa agaaaaagaa atccaatcac ttgggtttct ttttctttta
     1801 ttattatgat gaatcaagct ttctgttttt gtcacgtatg ttgtaatctt tacgaaagag
     1861 tagagttggc tactcataat caaccatact tcccatcatc gctaaatacg aaataaatca
     1921 gcattcctac accaatcaaa gcacaagctg caccaagaaa agggatgaca ttcccaaagt
     1981 tatctgtatt cataagtatg ccaccaccca caaacaaaaa gccgccagca atcaggtttt
     2041 tcattttatt catctccttt cttacgttat agtatttcct tctttcaatg agtattttga
     2101 aagctatctt attgtatgat gttcttctag gcctcttctt tattatacag gccattttcg
     2161 ttatctcata gaaatattcc tttttatctg aaaactattg tataccgtat gacatttttc
     2221 ttcatgaagt tgtaagtata ttctcattca aatgaaaatt tcatcataga agagattgta
     2281 tttctaaatt cttaagagta aaatacgaag tataacttgg atttggaagg atgattggat
     2341 gaaagctatt acgcctgata tgacaacaaa atttaacaaa cagtttcaag caaatatcaa
     2401 acagcaggca ttgcagcggg cagttgtgaa gaacggaatt actgcttctg ctgaaaatgt
     2461 ttcagcacat gtggagaata caccggtatt ttctatagat ttggctacgg ggaaagtggc
     2521 taatcaaatg caatcggggc gttgctggat gtttgctgca ctgaacacat tccgtcataa
     2581 gatgctgaat caattccatt taaaagagtt tgaattatca caaaattaca cttttttctg
     2641 ggataaatat gaaaaggcaa attatttcta tgaaaacatc attgcaacag gaaaagaggc
     2701 aatcgatagc cggaaagtag ctttcttact cgctactcct caacaagatg gcggccaatg
     2761 ggatatgatc gtttcattat tccaaaaata tggcgttgtg cctaaatcgg tgatgccgga
     2821 aagtgcgaat agttcaaatt ctcgagattt gaataactac ttgaacaaat tactgcgtaa
     2881 agatgcagta gtgttacgga aaatggttgc tcaaggagaa acattagacg ctattgaaga
     2941 aaagaaagaa gaaatgctag aaagcattta taacttctta gctatctcat taggaacacc
     3001 tccaaaagaa ttcgattttg agtaccgcga tgaagaaaag aactatcatc ttgaccgagg
     3061 actgacacca caaatttttt atgataaata catcggtgta aaattagatg attatgttag
     3121 cgtgatcaat gcaccaacaa aagacaaacc attcaatcgt tcttatacag tagagatgct
     3181 aggaaatgtc gttggcggga aagaagtcaa atatctgaat gttgatatgg aaactttcaa
     3241 aaaattagcg attgctcagc ttgaagaagg agaatctgtt tggtttggtt gtgatgtagg
     3301 tcaatcttct actagaacta gtggcatcat ggccttagat gcttattcaa tggatgatct
     3361 atttgatacg gattttacaa tgactaaagc tgaacgttta gattttggag aaagtctgat
     3421 gacccatgcg atggtattga ccggtgttga cttagtagac gggcaatcaa caaaatggaa
     3481 agtcgaaaat agctggggcg aaaaagttgg aaagaatggc ttctttgtta tgagtgatgc
     3541 ctggatggac gaatatacgt accaaatcgt tgtaagaaaa gatttattga cgaaagagca
     3601 attaaatgcg ttcaatgaag aaccaattgt tctatctccg tgggatccaa tgggtgcttt
     3661 agcatagacg agtatttcaa tgaagagtat gtagtaaaga taaaaagagc tggcttaagc
     3721 cagctctttt tatctttaaa gtccattccc tgttttttat ggtccctgtg ctataattct
     3781 aaataaagga taaggattgg aaataatcct tttatcatta aaaatatgat gacgaagtag
     3841 aataaaattg ggagtagggg ggaaagtcat ggatatccaa actgttttat ctgatctgaa
     3901 attaaatggt aaagtgattc cagttgttgg tggcgatgtt aatcagacct atcgtataaa
     3961 aaccgaacat cgtgcttatt ttttaaaaat ccatccgaat gtaaaaaaag gattttttga
     4021 agcagaagta gacggattaa aagaactgtc agcattcgta cgtgtaccgg atacgtatat
     4081 gctaggtgaa acaagtgaag gcgcttattt gttaatggaa tggatcgagc cgggaaaagg
     4141 ggatcaacga gatcttgctg cagctttagc taatctccat cagcaaacag cgccacaatt
     4201 tggttttcgt aaagataact atttgggtac acttgttcag aaaaattctt ttgaagaaga
     4261 ttggtggact tttttcttta aagatcggct tgaatcccag atttctttgg cagaagaaac
     4321 gaatcgatgg aatgtacagc gtcaagaaaa gtatctgcga tttaaagaac gtgtattgaa
     4381 atcggttgaa ccaaaaaaga tcactccacg cctcttgcac ggagacctgt ggagtggtaa
     4441 tgtgttcttt gaccagcaag ggcatccagt ttttgtcgac ccagctgttt cttatgggaa
     4501 tcgggaacaa gatattgcaa tgagccagtt attcggtggt ttccgaccgg aatttttaga
     4561 tgcttatcaa actatatttc cattagaaaa gggatggaaa gaccgactgc cgatttacca
     4621 gttatattat cttttggcac atttgaatat gtttggagaa agttacggtt cccaagtaga
     4681 tcaattacta gaaaattttt aagaggaggg cgtgtttttg gcaaaaaaat ataccaaaaa
     4741 gcatgaagtt tcatattatg agtgtgacat caaccaaacg atgacatttc cttcgatgtt
     4801 aggagtagtt atcaaaacgt ctgaagatca aagcgaccag ttgggaagag gcagtgaatt
     4861 cgtcaatagc tttggactta cttgggtcat cacgaattat tccatggaga ttaatcgtct
     4921 ccctagagtc ggtgaagtaa tctcagtaac gactcaagcc atggagtaca ataagttttt
     4981 ctgttatcgg aacttctgga tccatgatga agatgggaaa gaattagtca aaatagaatc
     5041 tgttttcgta ttgatggatt ttgtgaatcg aaaaatgagc agtgttaatg aagagatcat
     5101 tgctcctttt gagagtgaga agatcaagaa aatcaagcgt caggaaaaaa ttgaaaagat
     5161 tgattcgggc ttcatgttgc catatcgtgt tcgtttttat gatatcgata gtaatcagca
     5221 tgttaataat gcgatgtatt ttaattggat cattgacgta ttaggatatg actttttgac
     5281 tacgcatgtt ccagaaaaag taattattcg atttgataaa gaagtagagt acgggaatga
     5341 gatcgaaagc cattttgaac aaatccctat cgaaaatggt gtcaaaacaa aacatgaaat
     5401 ccgaatgcaa gaacagctgt attgtgaagc aaatattata tggaaaaata aataaaaaag
     5461 aggttgtgac agaagggggc aacttcaaga aataagaaga aatttacgaa aattgtttct
     5521 caaatttttg taaattttcg acttagtttt cgaagaagct atttttgtca cagcctctct
     5581 ttttaagttt agctattaga taatgatgtt tagttttgga taaacgaaat caattcttca
     5641 cccgacaaac catagtttac agcaatcaat agttttaaac gtgctttttg actattaata
     5701 ctgttacaga aaataatccc cattttttct agttcttttc ccccgccttc ataatcataa
     5761 acaggctctg cgattccatt gaaacaacga gaaacaagta ctacagggat tttttggaca
     5821 agaagctttt ccaaagcagc taaggcttgt ggagggagat tccccgcacc taaagcttcg
     5881 attaccaaac cgtctacttt cgtatgggcg atggcttcca ataagtcccc ttgcatccca
     5941 gcatatgctt taacgatcgg gatagtccca tctacagcgg aaatgtccag tcgctttgtt
     6001 tctaaaagtt cctgcaagaa taaaattcga ttcttagtta ctaagccgat gggacccaat
     6061 gtaggtgttc ggaaagtagc aacatttgtg gtatgggtct ttgtcacgta gcgtgcagaa
     6121 tggatctcat cgttcatgac caccaaaacc cccttatcta gcgcttcttc acaacttgcg
     6181 acacgaatcg cactttcaaa attataaagg ccgtcacttc caagttcatt acttgaacgc
     6241 attgccccag tcaaaacaat tggtaatttg ttgccaatcg ttgtatcaag aaaaaaagca
     6301 gtttcttcta atgtatctgt accgtgtgtg atcaccactc cggatatacc tgatgcataa
     6361 gcggacaaga tacgttcttt taataccaac atgtgagaag gcatgatgtg tggtgaggga
     6421 agattgaaga tatcttcaac taataattct acatgcttgg ggattgtgat ttctgcatct
     6481 aataatgggt ttgccacatc aggactaaca ccgcccgtga gcatgttttc tttcatggcg
     6541 atcgttccgc cggtgtgtag tacaagtatt tttttcattt tacagacttc cttacgaata
     6601 attttgcata gccgttaaat cttattgtat actatataaa agagttttgc tatcagtgaa
     6661 gaataacgaa tagcctaact tatcataaaa aagctgacct tattaaaatg gaaaagactc
     6721 aaccttgacc tcctaataca atggagtatc tggttgagtt tcttttacaa gaaagcagcc
     6781 aaggaaatca atcacgaagg tggccggaaa tgatcagaat cggattaaca tcgtttaaag
     6841 aacatgacaa attaactggt aaaaagaata acactcttta tgaatatgca gggtttctac
     6901 ccttagtgga attagatact gcctattatg gaattccccg aaagtcctca gttgagaatt
     6961 ggataagtga agtacctgaa tcatttcgct ttgtagtcaa agtctatcaa ggaatcagcg
     7021 gtcaaggaga ctggaagcct tattatcaga ccgaagaaga gatgattgcg cattttttag
     7081 atgttatgtc gccaatggta gatgctggaa agatgttttg ctttttagtc caattcccct
     7141 catcattcaa atgtacgaaa gaaaatgtcc agtacttgcg caaacttaga aagtggtttg
     7201 agggttatcc tgtttctata gaattgcggg attattcttg gtacagcgat gaatttcttg
     7261 aacgtacaag aaactttatg tctagagccg ctttttcttt agccatcatc gatgagccac
     7321 agttgctgaa tacaacgatt ccttttgatc catttgtcac caatccgaac tttgctcttt
     7381 ttcgattcca tggtaggaat gcgcaaggat ggcaagcaaa tgataaagag tggcgtaaaa
     7441 aaagaacgtt atatcgttat tcagaaaaag aactgcaaga actagcacat gaagtcaaag
     7501 tagttgattc taagacaaaa gaggtaggtg tgatttttaa taataattct ggtggtgatg
     7561 cggctgaaaa tgcattagca ctgcaaaaaa tattaaatat caagccagat ggactcaatc
     7621 caacccaaat ggatctgttt taagggctta ttttattcaa gaaaggggcg aagtctatga
     7681 tcaaagctat tttttttgat attgacggaa cattggtcac caatcgttca aaagcgttgg
     7741 aatcaacaaa acaagcaatt gaatatgctc ggaaaaacgg cattttatgc ggtgtagcaa
     7801 cggggcgcag cccagtaaag atcaaagaaa tcattgatga attggaatta gatatgtatg
     7861 tcgtgtataa tggtcaactg gtttttactg cagatcgcac gattatcgac cacccttttg
     7921 aacaaaaagt attggaacat attgttgaat ttgcagatga gaaccatcga caaatcgttt
     7981 ttggtgcgag aaatcggtta gatggatcaa cgacgatgct attaggacaa tcgattttta
     8041 tcaagcgact agtcagcttt ttaccgcgta aattcccggt acgtctgatg aaaaaaatcc
     8101 tccaggtttt tagccctcac cgacaaaagg atcgttatga aacgttagag atattaaaag
     8161 aaccaattta tcaatgtata ttgctcagtc cggagtcaga acagaaaaag ttagaacatc
     8221 gctttcccga gtgtacgttt cagcgttcaa atacgtatac tgtagatatc atcccaaaag
     8281 gtggttcaaa attactaggc atccaagctt tcgcaaatgc tgtcgaaatt gaaatggaag
     8341 aaattatggc attcggcgat cattacaatg atatcgagat gctgaaaggt gtaggaattg
     8401 gagtggccat ggggaatgct cagatcgaag taaaacatgc tgcagacttt gtgactcaat
     8461 caaatgaaga agatgggata tacgaaggac tgaaacactt cggtctgatt tattagtcaa
     8521 tgaaagaagg aaaaaatcag tatggaagca gagacacctt ttcaaaaagt agaaacattc
     8581 cacaaaactt ttgatccaag aagaccagag atacccacgg cttttacaga aaatgaagct
     8641 catacacgtg ctgcgttcaa aatagaagaa cttgttgaat ttgttgcagc tacttcacct
     8701 aataaagaac aactgcatga agctgttatg ctgctgcacg aagcattgga taaagcagaa
     8761 gaaaaaatac ttggtaaaac acagtgggga agtgatccgc tggttgaaca agtagatgca
     8821 ctgacagata tcctttactt tacttatggt tctttttcat tactaggaat agtgcctgat
     8881 cgaatattcg aaatcgtcca tcaggcaaat atggggaaat tatttccaga tggaaaacct
     8941 cattatgacc ctgtaacaaa taaagtgttg aaacctgaaa actggcagat ggaatatgct
     9001 ccagaaccta aaatcgcggc agaaatccaa cgtcagattc aagaagcgat tgctaagaag
     9061 aaatccgctg atataggcat gtgcacaaat gaaaaagagt gatcagagtt tcactatttt
     9121 tgttatcttt atacgatgga aaaacaaaag attttcgttt aagttagtga atgcatgaaa
     9181 atagtatgct ataatctaga atagatgtct tttgcacgag agacgtatta tttggattta
     9241 tgccaagcag aacgccatct gttgcataaa agatgcatac tgaaaacgga ggaaccataa
     9301 atgggaaata atgttatcat cggaatcgtc attgcaatca ttatagtcgc cattgtcgtc
     9361 tttttggtta gttacttgat gaagaaaaaa aaccaagatc gattggatgc cttagaaaaa
     9421 cgcaaggaag aattatttga cttgccagtg attgaagaag tcgatgatgt taaaaaaatg
     9481 catctggttg ggcaaagcca aaataccttt cgtgaatgga gtcaaaaatg gaatgacata
     9541 tctacttcct cgttcgctga actagaaagt caaattttcg aagtggaaaa cctcaatgaa
     9601 agttttcggt tcttaaaagg aaaaaaagca gttgttgaag cagaagctac aatggaccaa
     9661 atggagaaac aagtgacgga aatccgtgaa ggtctaaagg aattgcggga aacggaagaa
     9721 cgcaactcac tagctgttca gcaggcactt gacgtctatg aagaactgaa agaaaaagtc
     9781 agagaagacg agcatgaata cggaccagct ctttttgaat tgcaaaaaca gatcaaagtg
     9841 atcgaaaaag aatttacgca gtttgtgact ttaaacactt ctggagaccc tgttgaagcc
     9901 cgcgaggttt tggataaagc agaaaaacat acgtatgaag tggaagctct gatgaaaaaa
     9961 attccaccgc tgtatgagga gctccatacc actttccctg aacaacttga agaaatcagt
    10021 gatacttacg agaaattgat ggaagaacaa tatgtattcc cagaagaaga tcttgctgaa
    10081 gatatcgcaa aagtaagtcg aagaattgaa aattcattag ccaatcttga aaaaacagaa
    10141 gttgaaacgg tcgaatttga aaaccgtgaa acagctgatt tgattgattc gttatatgat
    10201 atcttagaac gggaaatgga agctcagaga tatgtaaaaa ctaaccaatc aacgattgca
    10261 gagtatatca aacatacaac aaagaataac cgtcaattat tgattgagct ggatcacaca
    10321 tctcaaagct atacattgaa ccacaatgaa attggccgtg tacgaggttt ccaaaccgaa
    10381 gtggaagaaa tggaacgtca aaatgaacag atgattccac agatccgtca acacgaaatt
    10441 ccttattcag aagtgcgcac gttctataaa acagtcttca aagtcttaga agatatcgaa
    10501 aagcaacaag tagagatcga cgactcatta catgaattga gaaaaggcga aaaagaagcg
    10561 caagaaaaga tcgatacatt cgaattcaaa ttgcgcagtt tgaaacgttt tgtagaaaaa
    10621 caacgtttgc ctggcttgcc gaatgattac ctagaattct tttttgttgc tactgaccgt
    10681 attgaagaac taagtgttgt cttgaataaa attcgagtaa acatggaaga ggtcaatcgt
    10741 ttagttgctc tatgtgaaga agatctagaa ttattagata agaagacaca tgatttagta
    10801 gatgcagcag cattaacgga gcaaatgctc caatatgcaa atcgttatcg tcatacacac
    10861 gaagaagtga gagaagcaat tgataaaagc tactatttat tcaataaaga atatcactat
    10921 caagaagcat tagacgaaat cggtacagca ttagagcgag tagaacctgg tgctttcaaa
    10981 cgcatcgaag atttttattt taatcatcca gacttagtat aaagcaaaaa agttagtaaa
    11041 ccagcaagag caagacggat tattgtcttg ttcttgtctt tttttgtata tttgaaaatt
    11101 gaaacaagtg aaaatttcac ctgctcttga aagcaccttg gacaaccgtt ataatagaaa
    11161 agaatttcaa aaaagagggg tttcttatga tatattttga taacagtgca acaaccccaa
    11221 tctttccgca aagcttagat gcatatgtaa aaaccagtca gcggattatt gggaatccat
    11281 caagcttgca tgatttaggc aatcaagcta accggttgtt gcagcaagca agaaagcaga
    11341 tcgctgattt gatccatgta gaaccagaag aaatctattt tacttcaggc ggaacagaag
    11401 gagataactg ggtattaaaa ggaacgatga tcgaaaaaag agaatatggg aatcatatga
    11461 tcatttcagg agtcgaacat ccggccgtca gcgagacagc agaacaatta aaagaattag
    11521 gaatcgaagt aagtatcgcc ccagtggata aacgcggatt tgtacgtgtc gacgaattga
    11581 aagaattaat aagaaaagag acagtattag tctctgttat ggctgtgaat aatgaagtag
    11641 gatcgattca gcccatccag gaaatcagtg atcttttgga tgattttcct aaaattcatt
    11701 tccatgtaga tgctgttcag gcgattggaa aagtaccatt ctcgcaatgg ttgacagaaa
    11761 gagttgattt tgcaacattt tcagctcata aattccatgg cccacgggga actggtttca
    11821 tttattggaa aaagggtcgt cgtttagcac cattactgac aggtggaggg caagaaagaa
    11881 atcagcgaag tgggacagaa aatgttccag gtattgtggc tatggttaaa gctttacgtt
    11941 tatcattaga gataaaggaa caaaaacctg agcagacaca acgcttaaaa gtagctctaa
    12001 tcaatgcgtt gaagacgtat gagaaagtga cgattttttc agaaggaact gactatgcac
    12061 cgcatatttt atgttttgct ctaaaaggaa ttcgcggcga agttctcgtc catgccttag
    12121 aagaaaaaca aatatttgtt tctactacta gtgcctgctc ctcacgtaaa catatggcaa
    12181 gcagtacatt gcacgcaatg catgtaccaa atgatctggc tacatctgct gttcgaatca
    12241 gcttagatga aaacaattcg cttgcagaag tcgagcaatt tatgattatt ttcaagcagc
    12301 tttataagaa attttctgca atcaattaaa agaggagtgt tcttgtgaaa tacagtgaaa
    12361 ttatggtccg ttatggggaa ctttcgacaa aaggaaagaa tcgaaaaagc tttatcatgc
    12421 aactagcaca aaatgtcaga caagctttga aagactttcc agaaatcaaa atccatgctg
    12481 atcgggaccg gatgcatctt ttattgaatg gcgcagacgg gcagctagtt attccaaaac
    12541 tagcaaaaat atttgggatc caaaatttct ctccaagtat tcgtgtagaa aaagatgtcg
    12601 aagttttgaa acaagctgtt caagacatca tgaaagaaat ttatactggg aaagaaacat
    12661 ttaaaattat cgctaaaaga agcgatcacc aatttgaatt gacaagtaat gaattgaatc
    12721 aaacattagg taatgctgtt tttgatattt tcccgcatat ccaagttcaa atgcgtcaac
    12781 cagatattcc attacgtgta gagattcggc gtgatggcgc ttatctatcg tatgaaacga
    12841 tcaagggagc tggaggattg cccgtaggaa caagcggaaa aggaatgctt atgctttctg
    12901 gggggattga ttctcctgta gcagggtact ttgccatgaa gcggggagtg gaaattgaag
    12961 ctgttcattt tgctagtccg ccgtatacaa gtgaacaagc actgcaaaaa gcaaaagatc
    13021 taacagccaa actagcacct tatgtgggaa cgatccattt tatcgaagtg ccatttaccg
    13081 agattcaaga agaaatcaaa aagtcagtgc cacaaggata ttggatgaca attactcgtc
    13141 gaatgatgtt gcgtttgacc gatgaaattc gccgtattcg tcatggttta gtcattttga
    13201 atggtgaatc attaggtcaa gtggcttcac aaactttgca aagtatggtg gctatcaatg
    13261 aagtaacgaa tacgccaatc attcggcctg tagcgacaat ggataaactt gaaatcattg
    13321 aagtagcaga acagatcgat acatttaatc tttctatcca gccttttgaa gattgctgta
    13381 cgatttttgc tcctccacag ccaaaaacac gccctcaact ggaaaaggtc catcaatatg
    13441 aagagcgttt agcaatagat gaaatgatcc aacgagcact agctggcttg aagatggaag
    13501 agatacaagc agaatcgtct aatgaaaaaa ctgaagaatt ttcagaattg ctataagagg
    13561 ttatgaaaat agtgttttga ccagagtatt agagaaacaa aacgaaaaaa tagctccatg
    13621 tattttaccg tttttgaact aatgtcgaag attagctgat tgaataccat ttatcaagaa
    13681 gttatggaaa agccggttct tttttactaa ctgaaaaata aaattttatt tagagatcaa
    13741 gctacagttg ataaatgata taaaaaagag aatttcccat gaaatagcga ggttgtgaca
    13801 gaagtgggca gcttcaagaa ataagaagga atttacgaaa attgcttttc aaatttttgt
    13861 gaaatttcgg cttatttttc gaagaagtta cttctggaac accgtgtatc agaggttgcg
    13921 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt
    13981 acgtttggtt gagcttatta ccgcagatgc aagcttttga acaccgtttt atttgtctca
    14041 cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt acactaaata
    14101 tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac tgccaaaagc
    14161 aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg actcaggtat
    14221 aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg caacgatccg
    14281 cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg atgtcccttt
    14341 tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa tcgcattagt
    14401 aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa atgaaaatct
    14461 aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa ttgatggaga
    14521 aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg tgacagtagc
    14581 aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg tcaaaggaaa
    14641 tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt atgtcaatgt
    14701 tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg agaattactc
    14761 agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa ctcgtcgtaa
    14821 ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac ttgttgacta
    14881 aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa ctggcacatt
    14941 cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt gaaggtagct
    15001 tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta actcacttga
    15061 gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat acgtcctaga
    15121 atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat gacggaagaa
    15181 aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta tcagcattgg
    15241 ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta ttcaatcgta
    15301 atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga tacgaccttg
    15361 caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg gctgcctggt
    15421 atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag agagcaaggg
    15481 atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga atggaaagaa
    15541 gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt agattacagt
    15601 agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt ttttgttacc
    15661 ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga tcctcaagca
    15721 cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc cttttatcat
    15781 atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac ccgtccagaa
    15841 acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta tcaagcgctc
    15901 atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat tgcagatgaa
    15961 tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca tgatccaaac
    16021 gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga tgatgatggt
    16081 acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc tcgtaaagca
    16141 atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat gatccacagt
    16201 gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac tcaatggttt
    16261 gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga tcaagcagtg
    16321 gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa tgtccatgat
    16381 tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta tcacaaagaa
    16441 acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg ggtacaagat
    16501 cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac aatgggctgg
    16561 ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt agtaaccggt
    16621 tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga atttactggc
    16681 gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca agggcggaag
    16741 atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa gtatggagca
    16801 gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt ccgcttcagc
    16861 tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc ttcacgtttc
    16921 gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg agaaaaatca
    16981 gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt aactgagcta
    17041 tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat ctgggatgat
    17101 ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga tgctgtttca
    17161 aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg tttattgcat
    17221 ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca gggaaattct
    17281 ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac agcttctaaa
    17341 gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc agaagtgaat
    17401 acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa aatcgatcaa
    17461 tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga gttgacgata
    17521 tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg tgcagaaatc
    17581 ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt agaaaaagaa
    17641 ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa tgaacgtttt
    17701 gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa agattattta
    17761 gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca ataagaatag
    17821 aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga acatcgttac
    17881 aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga cataaatttt
    17941 gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg tggatcatgt
    18001 atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt ttctctttgt
    18061 catactttta tttttcttat gtgttctatt tgttataata aaagagaaat gggggaattg
    18121 ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt tggttcacgt
    18181 cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga gagaaaagta
    18241 aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta tttgagaagc
    18301 ctattagaag aggctgggct gacagtaggt acatttactt caccttatat cgaaacgttc
    18361 aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat ccagcttgta
    18421 aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc tggtattact
    18481 gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa agtggacgta
    18541 gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc tgtaccaatg
    18601 ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga tacaattgaa
    18661 gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt aacaggaaat
    18721 attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa tgcaccgctt
    18781 tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat gtggggagaa
    18841 gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc gcttttaggg
    18901 caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta ctgtcaattg
    18961 gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc tcgatggcca
    19021 ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc ccataatacg
    19081 catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata tcaaatcaac
    19141 attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg attgcagcaa
    19201 gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat cgaattaagt
    19261 gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca attcggatta
    19321 gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg ttcactttat
    19381 ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga agtataatgc
    19441 agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt acgaagccac
    19501 acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt taaaattctt
    19561 aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg aatttggcaa
    19621 aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac gtttttcgca
    19681 aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag aagaacatca
    19741 gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt tattgaagaa
    19801 gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc aacgagcaaa
    19861 accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga agaaagaaac
    19921 attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg agatcccggt
    19981 agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa cagctggggt
    20041 tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct cttttcgtat
    20101 cttattttag ataagataga aaggagatgt ttttttggga aaacgattga tcaaagaagt
    20161 acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag ctttatcgga
    20221 tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg tgatgtcgat
    20281 tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg ctactttgca
    20341 tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca aagccttgat
    20401 cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg ttcgtaccag
    20461 ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag aacatttggt
    20521 ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt tcatcggttc
    20581 gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac gttattgtgc
    20641 agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat cgcagcagga
    20701 tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca ctgtactgga
    20761 ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa tgatggaaga
    20821 gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat tgtaattttg
    20881 tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca atgttacaat
    20941 ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac agtaaaatgg
    21001 ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga cgtattcgtt
    21061 cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca agcagtgact
    21121 ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa agcttaattt
    21181 tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa gcgagtaaca
    21241 aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt atgaaaaagt
    21301 aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga acaaacaaaa
    21361 atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg ctgatttcat
    21421 aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt ggatgtcttt
    21481 ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc aatttatatt
    21541 ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt cgctgagctt
    21601 cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga atatctggac
    21661 cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca agaccttctt
    21721 ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc ccgctaccat
    21781 cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg ctagttaacg
    21841 ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct acatcttgtg
    21901 ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata aaatattttg
    21961 gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg gaagtatgga
    22021 tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa ttgatcaaat
    22081 gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact gtatcgtctg
    22141 gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg gccatcgctt
    22201 ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga ttgatttcgt
    22261 gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga ccgttgacga
    22321 tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc acagcggcat
    22381 ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg atacgtcctt
    22441 cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat ttagtaaatg
    22501 ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct tccccgatac
    22561 gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat ttgaagtctc
    22621 cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca tctgggatac
    22681 tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc gtatcttcat
    22741 tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg tttgtgatca
    22801 acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc aagtagggta
    22861 ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact ttgtgtaagt
    22921 tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa tcgtcttccg
    22981 ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc ccatacgtat
    23041 ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta tttttgatgg
    23101 aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc gtactctaga
    23161 tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc ttccacacgt
    23221 tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc ttcccgttta
    23281 gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt gtctccttta
    23341 tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa cgaggggaca
    23401 agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa agagacaagc
    23461 ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat aaaaaatata
    23521 caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc aactagattg
    23581 aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt atgagagaag
    23641 tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta acaaaagatt
    23701 aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata agaaattctt
    23761 gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac ttcctacgat
    23821 tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg tgaagcaaca
    23881 agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct tgttaggtta
    23941 ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt tgttcgaaaa
    24001 gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat tgatcactcg
    24061 tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac gtatcggttt
    24121 tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa gtgtgacact
    24181 cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag cgattgctaa
    24241 ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca acagtatctt
    24301 gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa agtttgaaga
    24361 aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct tattccgttt
    24421 gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg tattgatcat
    24481 ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt tgattgcgtt
    24541 tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg tgttcatgat
    24601 gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg ccaaaccttc
    24661 gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata tcgaatttca
    24721 aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa atgtcagttt
    24781 tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg gaaaatctac
    24841 gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct tgatcgatgg
    24901 agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt ttattccgca
    24961 aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga aagaagatgc
    25021 tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat tcatttctcg
    25081 aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt caggtggaca
    25141 aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct atatttttga
    25201 tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc gtctgaaaaa
    25261 agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga tcatgcatgc
    25321 agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc atcgggagtt
    25381 gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa aggaggaatt
    25441 agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag accgtatcgt
    25501 gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa cgtggctttg
    25561 ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa tggcgaatca
    25621 atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg aatagggtat
    25681 tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag tgccatgcat
    25741 gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata tttcgataaa
    25801 aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt cagcggtgct
    25861 ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt ggctgcagca
    25921 atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat tccaacatcg
    25981 atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag catgcagaat
    26041 tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag tgtattgaaa
    26101 gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca cagcttgaaa
    26161 tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt tcaattaact
    26221 gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat tactggggcg
    26281 atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag tcagccaatg
    26341 gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac gaaacgtgta
    26401 ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc actgccagaa
    26461 acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc gaagaaacca
    26521 ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt ggtcggtccg
    26581 accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga cgtagacaaa
    26641 ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga tgtgcgttcg
    26701 ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc agataatatc
    26761 cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa aacagcaaac
    26821 gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa ttctgaggga
    26881 gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt ggtctccgat
    26941 cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt agaagcgttg
    27001 attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat cgctcaccgt
    27061 ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca gatcattgaa
    27121 aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact gtataacagc
    27181 caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa acttattttt
    27241 tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg acacggagat
    27301 ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc gtttaacgca
    27361 cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt ttcaaatcga
    27421 acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa tagaagaaaa
    27481 tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa atagacatct
    27541 ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct atgatacctt
    27601 tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat ggaacggttt
    27661 atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt gacgatctgg
    27721 tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag aacgaatatc
    27781 caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc ggagaatgtg
    27841 acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc gctgatcggg
    27901 atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat tggtgctgga
    27961 tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg tcgcccagct
    28021 aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa catccagcat
    28081 tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag ataggcagta
    28141 gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt tatttggttt
    28201 agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa gaactgtttt
    28261 ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata tagttgtcac
    28321 gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct aaaattttgt
    28381 ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca gttgcttgcc
    28441 cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa gcaaatcgtt
    28501 taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata cccataacaa
    28561 ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata cctgctgtaa
    28621 ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct tgagcgtcta
    28681 agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg ccgcttaaca
    28741 tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca cctcgtgaag
    28801 attgttcaat gactgtagga attaaattca taatagagtt cctccttgat ttcgtttaga
    28861 aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt ttggtcaaaa
    28921 aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg gtatgataag
    28981 cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg ccttatcgga
    29041 gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg tcacttggaa
    29101 aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga gacgctgaat
    29161 caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat ggaagaatat
    29221 gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc gtatctccaa
    29281 tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga gctatttaag
    29341 aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat tggtggatat
    29401 gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac tgaaatgatc
    29461 aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt cttctcgaaa
    29521 gatgatgttt gaagctgata ttttgaagca ttgccgttgc acatgagagc gtggtaatgc
    29581 tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat gttacaaatc
    29641 tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc atttgcagaa
    29701 gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa agatggttat
    29761 ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg gctgattcga
    29821 gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag caaagaattt
    29881 ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca aaaaaattac
    29941 cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg tatcgaagaa
    30001 aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata ttgcagcttt
    30061 catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct ggacttattg
    30121 atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat agaaggagta
    30181 catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt tccaaaagca
    30241 attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga actcaaaata
    30301 gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc aacgaaaagt
    30361 aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg taaaacagcg
    30421 ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga ttcattgcaa
    30481 atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat gaataatgtt
    30541 ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgc tgattttcag
    30601 cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc tatcatagct
    30661 ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg agcgacagaa
    30721 gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat tggttcccaa
    30781 gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat ccactggaac
    30841 aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca tagtatcacg
    30901 gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt agatacgaag
    30961 cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc agaaggttta
    31021 gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca aggtattgga
    31081 tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc aacagaacaa
    31141 gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg taaccgtttg
    31201 gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat tgagcaaaca
    31261 atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg taggggtaga
    31321 aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc agctgacgaa
    31381 taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag tgaatcggca
    31441 aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg cgcatgaagc
    31501 ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga ttaccgatgc
    31561 tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg cgatgcgtgc
    31621 tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc tgctgcctcg
    31681 tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa caagagggcc
    31741 aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt ttgctgttaa
    31801 gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa gaaaaaatag
    31861 cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa ctatcttgaa
    31921 tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt tagatccatt
    31981 gactaagaga tggcgttttg ctgaaggatt tgagattgct gtaacggata ccgtcgggtt
    32041 catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag aagaaagtca
    32101 aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta ttttacagga
    32161 gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga tactgactgt
    32221 ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat tcccaaatgt
    32281 attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa tcaaacgtca
    32341 gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag gacagaaatt
    32401 aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag aaacaaacga
    32461 atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa accaataaaa
    32521 ttttattttt ttaa
//
LOCUS       DAXLPY010000024        31542 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.024, whole genome shotgun sequence.
ACCESSION   DAXLPY010000024 DAXLPY010000000
VERSION     DAXLPY010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.024"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            83..835
                     /locus_tag="ACF3UF_001261"
     CDS             83..835
                     /locus_tag="ACF3UF_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3671403.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            832..1746
                     /gene="pfkB"
                     /locus_tag="ACF3UF_001262"
     CDS             832..1746
                     /gene="pfkB"
                     /locus_tag="ACF3UF_001262"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFD3671404.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            1764..3695
                     /locus_tag="ACF3UF_001263"
     CDS             1764..3695
                     /locus_tag="ACF3UF_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFD3671405.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(3805..5364)
                     /locus_tag="ACF3UF_001264"
     CDS             complement(3805..5364)
                     /locus_tag="ACF3UF_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFD3671406.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            5519..7753
                     /gene="pcrA"
                     /locus_tag="ACF3UF_001265"
     CDS             5519..7753
                     /gene="pcrA"
                     /locus_tag="ACF3UF_001265"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFD3671407.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            7770..9806
                     /gene="ligA"
                     /locus_tag="ACF3UF_001266"
     CDS             7770..9806
                     /gene="ligA"
                     /locus_tag="ACF3UF_001266"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFD3671408.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            9912..10217
                     /gene="gatC"
                     /locus_tag="ACF3UF_001267"
     CDS             9912..10217
                     /gene="gatC"
                     /locus_tag="ACF3UF_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFD3671409.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            10217..11689
                     /gene="gatA"
                     /locus_tag="ACF3UF_001268"
     CDS             10217..11689
                     /gene="gatA"
                     /locus_tag="ACF3UF_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFD3671410.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            11686..13116
                     /gene="gatB"
                     /locus_tag="ACF3UF_001269"
     CDS             11686..13116
                     /gene="gatB"
                     /locus_tag="ACF3UF_001269"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFD3671411.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            13126..14181
                     /locus_tag="ACF3UF_001270"
     CDS             13126..14181
                     /locus_tag="ACF3UF_001270"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFD3671412.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHADDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            14292..15665
                     /gene="rlmD"
                     /locus_tag="ACF3UF_001271"
     CDS             14292..15665
                     /gene="rlmD"
                     /locus_tag="ACF3UF_001271"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFD3671413.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            15668..15796
                     /locus_tag="ACF3UF_001272"
     CDS             15668..15796
                     /locus_tag="ACF3UF_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFD3671414.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            16236..16424
                     /locus_tag="ACF3UF_001273"
     CDS             16236..16424
                     /locus_tag="ACF3UF_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFD3671415.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            16502..17515
                     /locus_tag="ACF3UF_001274"
     CDS             16502..17515
                     /locus_tag="ACF3UF_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3671416.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(17582..18616)
                     /locus_tag="ACF3UF_001275"
     CDS             complement(17582..18616)
                     /locus_tag="ACF3UF_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3671417.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            18731..20956
                     /locus_tag="ACF3UF_001276"
     CDS             18731..20956
                     /locus_tag="ACF3UF_001276"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFD3671418.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            20974..22857
                     /locus_tag="ACF3UF_001277"
     CDS             20974..22857
                     /locus_tag="ACF3UF_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFD3671419.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            22838..23812
                     /locus_tag="ACF3UF_001278"
     CDS             22838..23812
                     /locus_tag="ACF3UF_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFD3671420.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            24471..25493
                     /gene="aroF"
                     /locus_tag="ACF3UF_001279"
     CDS             24471..25493
                     /gene="aroF"
                     /locus_tag="ACF3UF_001279"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFD3671421.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            25526..26590
                     /gene="aroB"
                     /locus_tag="ACF3UF_001280"
     CDS             25526..26590
                     /gene="aroB"
                     /locus_tag="ACF3UF_001280"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFD3671422.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            26592..27758
                     /gene="aroC"
                     /locus_tag="ACF3UF_001281"
     CDS             26592..27758
                     /gene="aroC"
                     /locus_tag="ACF3UF_001281"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFD3671423.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            27775..28866
                     /locus_tag="ACF3UF_001282"
     CDS             27775..28866
                     /locus_tag="ACF3UF_001282"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFD3671424.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            28879..30174
                     /gene="aroA"
                     /locus_tag="ACF3UF_001283"
     CDS             28879..30174
                     /gene="aroA"
                     /locus_tag="ACF3UF_001283"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFD3671425.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREIGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            30167..30676
                     /locus_tag="ACF3UF_001284"
     CDS             30167..30676
                     /locus_tag="ACF3UF_001284"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFD3671426.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            30673..31509
                     /gene="pheA"
                     /locus_tag="ACF3UF_001285"
     CDS             30673..31509
                     /gene="pheA"
                     /locus_tag="ACF3UF_001285"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFD3671427.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
BASE COUNT        10487 a         5802 c         6940 g         8313 t
ORIGIN      
        1 aacttttatg aacgtttttg actgatttat attgctagta gaaaaaaaat atgctattat
       61 ttgtattgag gtgatcgtga aaatgcttac agaggaacgc agacaaaaaa tcctagactt
      121 gcttgaacag cagaaaatcg tgaaatcaca agatcttgta aaccttttga atgcttctga
      181 atcaacgata agacgtgatt tacaagagct ggagaatagt gggtttctag aaagagttca
      241 tggcggagct aagaaagagc aattattgaa ttttgagcag aatatgagtg aaaaatcact
      301 caaaaacgtt cacgaaaaac agcaaatcgc caaatcggca gctgaaacca ttaatgacga
      361 agatgtcatt tatttagacg ctggctctac tacgttagaa atgattcctt ttctgcaagg
      421 aaaacagatc acagtagtga caaattccgt tcaacatgcg gcaaatttag ttgatttgga
      481 gcttgctacc attattttag gtggaacgat aaagctggca actaatgctg ttttaggatc
      541 taatgcgata gaacaactaa aaaattttca ttttaataaa gcatttatgg gaatgaacgg
      601 tgcccatctt gaacaaggat tcacgactcc ggatccagaa gaggcagctg ttaaacgttt
      661 agccatgaaa aattccgaag agacatttgt attgattgat cataccaaat tcaaccagtt
      721 gtccttcacc tctgttgcac ctttggaagc agccacgatc ataaccgagc gttgtccatt
      781 agaattcgtt aatgaattcc gtgaaaagac aacaattaag gaggcaatac aatgatttac
      841 acagtaacac ttaatccatc aattgattat atcgtacgcg tagatgggtt aaaactaggc
      901 gatttgaacc gaatgaagga agacttcaag ttacctggag gaaaagggat caatgtttcc
      961 cgtattttga aacggatcga ttctcaatct acagcactag ggtttttagg agggttcact
     1021 ggcgaattta tttcgaagtg gcttgaaaaa gaacaaatcc agtctttgtt cacaaccgta
     1081 aaagaagata caagaatcaa tatcaaacta aaatcagaca ctgaaactga gatcaatggc
     1141 ttaggcccat ctatttcaga tgaagaaatc gatgagttga agcaagcatt aggaacagta
     1201 ggacaaggag atatcgtcgt attgtcagga agcgcgccag ctagcctgcg aaaaggattt
     1261 tatcaagaac tgattgatat cattcgagaa aaaggtgcag atttcgtgat tgatacaaca
     1321 ggtgatgacc taaaaaatgc acttgttaag aaaccgttgt tgatcaaacc aaacaatcac
     1381 gaattagctg agctttacaa cacaaccttc caatctgtag aagaaatcat tccgtatggg
     1441 aaaaaattac tagctgaagg ggcacagaat gtgctgatct caatggctgg agacggtgct
     1501 ttgctcttca cggaacaagg aacttataaa acgaatgtat tagttcgccc attgaaaaat
     1561 tcagtaggtg caggggattc aatgattgct ggctttattg gggcttacag ccgtacgaaa
     1621 gatccaatcg aagcctttaa atggggagtt gcttgcggaa gcgcaacagc tttttctgat
     1681 gacttggcag ctcgcgaatt gattgatgag ttgctgccag aagttgaaat cacaaaaatt
     1741 gattagtttc aaggaggata atcatgaata tcaaggattt aatggtcaaa gaagcgatga
     1801 tcatggattt gcaagcgact gataaaaaag gcgcaatcga tgaaatggtc caaaaaatgt
     1861 ttgatgccgg ccggatttcc gatatcgaaa catataaaga aggaattcta gcccgcgaag
     1921 cacaaacttc tacaggtctt ggtgatggaa tcgccatgcc tcacgcgaaa aacagtgcag
     1981 ttaaagaagc aacagtttta ttcgcaaaaa gccaaaaagg agtagattat gaagccttag
     2041 acggacagcc aacttatctg tttttcatga tcgcagctcc agaaggcgca aacgacacac
     2101 atttgcaagc attagcagca ctatctcgat tgctgattga tgcagatttc gtaggaaaat
     2161 taaaagaagc aaatacacca gaagaagtcc aagacttgtt ccaaacagct gaagagcaaa
     2221 aagaagcaga agaaaaagca gaacaagaaa cacaagctgc agaagcttct gctcatccag
     2281 aaagaaaatt cgttgttgcc gttacagctt gtccaacagg gatcgctcac acttacatgg
     2341 cagaagatgc tttgaagaaa aaagcgaaag aaatgggtgt ggagatcaaa gtcgaaacga
     2401 acggttcaga aggaatcaaa aaccgattga ctgctgaaga catcgcccgt gcagaaggtg
     2461 taatcgttgc agcagacaaa aaagtagaga tgaatcgctt tgacggaaaa gaactgatca
     2521 atcgtcctgt cagtgatggt atccgtaaac cagaagagtt gatcaatcta gcccttagtg
     2581 gtactgcacc agtattccat ggtgatggaa aagaaagcag ttcagaagaa ggaaatgcgg
     2641 atggtactat cggacaaaga atttacaaag atttgatgaa cggcgtatca cacatgttac
     2701 ctttcgttat tggtggagga atcgctattg cgctttcttt catgatcgac caatttattg
     2761 gcgtgccaca tgatcaatta tcaaatctag ggaattacaa tcaagctgct agctggttca
     2821 accaaatcgg acaagctgca tttggtttca tgctgccggt attagcagga tttattgctt
     2881 caagtatcgg tgaccgccct ggtttgatcg ttggatttgc tgctggtgca ttagctaata
     2941 caggcggtgc aggattctta ggtgcactga ttggtggatt cttagctggt tatgtcatcg
     3001 tatttttacg taaattattc aagaacttac caaaatcatt ggatggaatt aaaacgatcc
     3061 tcttttatcc agtgtttggc ttactgatta ctggtttctt gatgttgctg gtcaatgtcc
     3121 ctatgaaagc aatcaatgat gcattgaacg gtttcttgac aagtatgagt ggttcgaatg
     3181 ctgctttact tggtgcatta ttagctggaa tgatggcggc agatttaggc ggtccaatca
     3241 acaaagccgc ttatgtgttt ggtacagcaa ctttagctac gactgttgca actggcggaa
     3301 gtgtcgtgat ggcttctgtt atggctggag gaatggtacc tccattggca attttcgttg
     3361 ctacacgttt gtttaagaat aaattcagca aaacagatca agatgctggt ttgacgaaca
     3421 tcgtgatggg actatcgttt gtcacggaag gatcgattcc atttgcagca gctgacccga
     3481 ttcgtgccat tccaagtttt attattggtt ctgctttaac tggcggatta gtcggagctt
     3541 tcggaatcaa attactggct cctcacggcg ggattttcgt tgtattctta ctgagtcacc
     3601 cggtcatgta tttggtgttt attgctatcg gagcagtcgt atctggtgtg atttatggtt
     3661 tattgagaaa agctcctgca gtagcagaag catagaaata aaaaagaaga ggctgggttt
     3721 tcccagcctc ttctttttta tagaatcata tagaatcaag tagtgtagat gaatagttgt
     3781 tgtaaaatag tttttccatg ttcgttaaaa tgattgcttc aaatttgtga tagaagattt
     3841 agcctcgatt tcctgcttga ttcttggcaa gtttgcttca tcagtcaaga taaccaaaat
     3901 atctcctaca ttcatgatcg tatcaccgtg agtcaagatt tcctgatttc ctctgcgtat
     3961 agagattagc agcatatttt taggccaatt gaagtctcgt accattaatc cgtctaaaga
     4021 actctctgcc gttactggaa aatcaaaagt tgtccttgca ccttttagtg aggcggtctg
     4081 agtatttcca agtagacgtt ccaataatga ttcgtaaatt ggattaccgc cgagaaggtc
     4141 attgacgata taagcaacaa gagcagccaa tcctaaaggc atcagatgat taagagagcc
     4201 aaccatttct gtcactaaaa taattgctgt cagcggtgct tttccaatcg ctgtgaaata
     4261 accagccatg gcaataacga caaaatcctt gatgtagatt ggatccatcc cgaaatcaac
     4321 cataatgttt ccataaaagc taccgattaa agcccccaat gtcaatatcg gaaggaaaat
     4381 cccccctgga agacccccac cgtaagaaat catggaaaaa acgaatcgaa gaacaaacaa
     4441 accgataatc ataatgattg gcaaggaagc atgtccaaaa gctaaaacga tttgattgcc
     4501 tccgcctaga gtactaggcc ataaataacc aattggcaaa atcagcaaga aaggaacgaa
     4561 cccgtgaaaa taagctggta aaggcaatcg gttgtaaaat tttggcaaag ccagcaagac
     4621 attctgataa ataaaaccta agatgcctag aagtactcct aagatcacta aggaaccata
     4681 atatttcaac ggcaaagaag gaaggtcacc tagatataaa acaggtctca agccgaaaaa
     4741 gtaaagagag acgaagttag cagtgattgc tgaagcaaat gatgtcagcc aaacaagtgg
     4801 agaaaaggag tgatggattt cttctaaaac aaagagtaat cctgcgatag gagcattgaa
     4861 tgctgctgca agtccgctac ttgcaccgct agaaattaaa atcttttctt ctgaagatgg
     4921 actccgaaac aattgtccag ctccttgtcc aatggatgcg ccaagctgta tagaaggtcc
     4981 ttctctacct agaaaaaggc ccgcaccaac tgaaagtaca ccgccaatga actttttcca
     5041 taaaacagag aaccagttca ttgataattc cccgcgaagc tgtccctcta cttgtggaat
     5101 cccgcttccc ttgatatccg gttcattttt gaccagataa cccacgaaaa atgctgcaag
     5161 gatgcagcaa atagctaggc caattaagta aatcggctgt tcccgactca tttcatagat
     5221 acttcgaact aaatcgctta gcttttcgat agataatcga aacaggctaa cgacgattcc
     5281 tgtcagcagt ccaacaaata ttccttttag aataaaatat atctgagtct tatctaattt
     5341 cttgattttt cctttttttt ccattcaaac gcctcgcttt cttttaattt agcgcgaaat
     5401 caacgaattg acaaggaaaa atccataaaa agaaacaaat gattttgaac tagctagttt
     5461 aatgaaagcc aagaaaatgc tataattaac aagattgata aaagaaagga tgttgttaat
     5521 gtcatccaaa gctgaattat taaacgggat gaacccccgt cagaaagaag ctgttcttca
     5581 cactgacgga ccattactgc taatggcagg tgcaggaagt ggaaagacga gagtgctgac
     5641 acaccgcatt gcctatttga ttgaggaaaa agaagtcaat ccttggaaca tcctagcgat
     5701 tacttttacc aataaggctg caaaagaaat gaaagaacgt gtcaatgcga ttctcgcatc
     5761 tggaggcgaa gatgtctggg tatcgacttt tcactcgatg tgtgtgcgta ttttaagaag
     5821 agatgttgat tttatcgggt ataaccggaa ctttacaatc atcgattctt ctgaacagct
     5881 gaccttgatg aaacggatac taaaagaact gaacattgat ccgaaaaaat atgatcctcg
     5941 aagtatatta ggaacaatct ctcaagcaaa aaacagcctg cagacccctc aggattttgc
     6001 aaaaatgcaa ggcagttatt acgaagagat tgcggcaaaa tgttatgctg cttaccaaaa
     6061 agagcttcaa tataatcaat gtatggactt tgacgacctg atcatgaata cgattcgatt
     6121 atttgaagaa catcctgatt cactcacgta ttatcaaaac aaattccatt atattcatgt
     6181 agatgagtac caagatacaa atcacgcaca gtatacgcta gtcaatttat tggcaggtag
     6241 atttaggaac ctgtgcgtcg tgggagatgc agatcaaagt atttacggct ggcgcggtgc
     6301 agatatgcag aacatcttgg attttgaaaa agattatcca gatgctgcag taattttgct
     6361 agaacaaaac tatcgctcca cgaaaaacat ccttagcgca gcaaaccaag tcattgaaaa
     6421 caatagcaat cgaaaaccaa aaaacttgtg gacagaaaac aaagaaggaa acaagatcac
     6481 ttactaccgt gcagataatg aacgagacga aacccgtttt atcgtagacc ggatgcaaga
     6541 agagattcga agcaatcatc ggaattacgg cgactttgcc atcttgtacc ggacgaacgc
     6601 acaatctcgt gtaatggaag aaactctgtt gaaagcaaat attccttata aaatggttgg
     6661 agggcacaag ttctacgatc gtaaagaaat caaagatatt ttagcgtatt tgaatgtgct
     6721 ggtaaatcct caagattcaa tcagttttga gcgtatcgtt aattcgccca aacgaggcat
     6781 cggaccagga tctatcgaaa aactacgcag ttttgcttct cttcatgaat ggccactgct
     6841 tgaagcagcg caaaatgtgg atctggcaaa tatcggtgga aaagcaggac agcaattagg
     6901 tgcatttgga gagatgatcc aagaagtcac tcagatgatc ccatacttga cagtgacaga
     6961 attgacgaaa gaggttttgg atcgtagcgg atatctagaa gacttaaaaa tccaaaatac
     7021 attagaagca caagcacgca tcgaaaactt ggaggaattt ttaacggtca cacaagaatt
     7081 cgacaaacaa ttcgaacagc aaaatgaaga agacgctgat gcaccagaag aaaaactaac
     7141 ggtcttctta aatgatctgg cacttgtttc cgacattgac aatttagaag aagatgcttc
     7201 ccaagtgaca ttgatgactt tgcatgcagc caaaggatta gaatttccag ttgtattcct
     7261 gattggtcta gaagaggggg tttttccttt atctcgagca ttgatggaag aaagcgaact
     7321 ggaggaagaa cgccgtctcg catatgtggg gatcacgcga gcagaagaag cgttgtattt
     7381 aacaaatgct ttctccagaa cattatatgg acggacgcaa tataaccgac cttctcgttt
     7441 tgtagaagaa atcgatcagg agttactgga aatcgaaggc atgcgtccta cgcctaaaaa
     7501 aacgcctgta ttcgctaaaa aaacagcata tagctataaa cagccagaga cagcggttgt
     7561 tccctctaaa agtgctactg gaggggaaaa taacagctgg aaacctggag ataaagtcaa
     7621 acacaaaaaa tggggtctag gaacagtcgt ccgagtaagc gggacgtcga aggatctaga
     7681 actagatgtg gctttcccaa gtcaaggagt aaaacgtctt ttggctgcct ttgcgccaat
     7741 tgaaaaagct tagtagtgga gggtaaatga tggaacatga aatgacgatt gacgaagctg
     7801 ctaaacgagc agaagaactt cgtacaagac tgaaccaatg gtctcgcgaa tactacgtag
     7861 aagataaacc aacagtggaa gactatgttt atgataaaga atacgcagaa ttagtagcaa
     7921 tcgaggaaca atatcctgat ttgatcacgt ctgattctcc cactcaacga gtaggcggaa
     7981 aagtattaga aggttttgaa aaagtcactc atgatattcc gctttacagt ttgaacgacg
     8041 ttttcagcaa agaagagctg atagcttttg atcaacgtgt acaaaaagca gtgggacgtg
     8101 tagttgacta ttgctgtgaa ctaaaaatag atggactttc cgtttctttg cgttatgaag
     8161 atggaaattt cgtgagaggt gcgactcgcg gggatggaac tgtaggagaa aacatcactg
     8221 aaaacctaaa aactgtccgg tcggtcccaa tcaaattaaa agaaccaatg aacatcgaag
     8281 taagaggcga atgtttcatg ccaaaacggt catttgtcca attgaaccaa gacagagaag
     8341 cagagggaaa agatatcttt gcgaatcctc ggaacgccgc agctggttct ttgcgtcagt
     8401 tagattctaa aatcacagcg aaaagaaatc tggacacttt tttatacaca gtagctgatt
     8461 tcggtcctat gcaagcaaaa acccagtatg atgcgctaga agagctagaa aaaattggat
     8521 tccacacgaa tcgggaaaaa cgtctatgtc attcgattga tgaagtgtgg tcatacattg
     8581 aagaatatca tgacaaacgt gtggatttgc cctatgaaat cgatggaatc gtcatcaaag
     8641 tgaatgaatt ctcgctacaa gatcaacttg gttttactat caaagcaccg agatgggcag
     8701 cagcttacaa gtttccgcca gaagaagttg aaacgctaat cgaaaacatc gaatggacag
     8761 tcggtcgaac aggggtagta acgccaacag ctatcatgac accagtccga gtagcaggaa
     8821 cgacagtaag ccgtgccagc ctgcataacg gtgattatat taagttgaag gatatccgct
     8881 tgaaagatac agttctgatt tataaagcgg gagacatcat cccagaagtt tcgcaagtcg
     8941 tgttagataa acgacctaaa gacagcgaag aataccaatt gcctacacat tgtccagttt
     9001 gtggaagtga acttgtccat ttggatgaag aagtagcctt acggtgcatc aatcctaaat
     9061 gccctgctca aatgaaagaa ggtttgaacc actttgtttc aagaaatgcg atgaatatcg
     9121 atgggttggg gccgcgcgta ctagaacaga tgtatgataa aaaactagta gcagatgttg
     9181 ctgatcttta caaattgaca gaagaagagt tattgacgtt ggacaaaata aaagaaaaat
     9241 cagcaaataa tattttgaca gcaatcgaca acagcaaaga taattcggtc gagcggttga
     9301 ttttcgggtt aggaatccga catgtcggag cgaaagcagc aaaaatttta gcagaacatt
     9361 tcggtgatct agaaacattg agtaaaagtg actatgagtc gattattgcg cttgatacga
     9421 tcggtgatat cattgccgac agtgtagtca cttatttcag taacgaagaa gtccatgaat
     9481 tgatgaatga attaaaacaa gcaggcgtca atttcgaata caaagggctt cgaaatgccc
     9541 aattgcaaga agtcgagtct ccttttaaag aaaaaacagt agtccttact ggtaaactaa
     9601 cacgatttac tcgtgaagaa gcaaaagaga cgatcgaaaa tcttggcggg aaagtgactg
     9661 gtagcgtatc gaaaaaaacg gatatcgtgg tagcaggaga agatgctggc agcaagctga
     9721 ccaaagcaca agaattagga atcgaagttt ggacagaaga tcaaatggca gatgcattgg
     9781 ctaaaagtcg ctcagtagaa gaatgaaaaa tgagtttttt cagacaaatt tcaataaaca
     9841 atttcagaca cggcactctt gtgttaaaat agagagcaaa gtttttaact cgtttagaaa
     9901 gaaggggtag tatggcgatt agtgaagaac aagtgaaaca cgttgccaaa ttagcaaaac
     9961 ttgcgttcgc agatgaagaa cttgcaagtt ttaccgacca attaggtaaa atcatcgata
    10021 tggttgaaat gctggaagaa gtagatacgg aaggtgttcc atttacgtcg aatgtggttg
    10081 aaacagtaaa cgtgatgcga caagatcggg cgcaagctgg atggaaccgc gatgaattat
    10141 tgaaaaatgt gccggaaaca gaagacggct ttatcaaagt acccgcaatc atcgataatg
    10201 gggaggctgg cgcataatga cagaattaca caatcgttct ctagaagaac tgcatcatat
    10261 gcttgtatcg aaagaaatca ctgtacaaga tttgacaaaa acaacatttg aacgaatcaa
    10321 agaaacagag cctgaggtcg aggcattcat tacattgaac gaagaaaaag cattggaaca
    10381 ggcaaaagct ttagatgaaa aagggattga tgaaagcaac gtccttgctg gtattccaat
    10441 tggtatcaag gataatatcg taacaaaaga tatcttgaca accgctgcat ctaagatcct
    10501 ttacaatttt gaaccaattt atgatgcaac ggtcatggat aaaatctatc aagcagatat
    10561 gatccctgtt ggtaagctaa acatggatga atttgctatg ggtggaagta cagaaacttc
    10621 ttatttcaag aaaacaaaaa atgcttggga cccaacaaaa gtacctggtg gctcttctgg
    10681 tggttctgca gcagcagttg cagctggaca aattccagtt tctttaggta gtgatactgg
    10741 gggaagtatc cgccaaccag cagcttttaa cggcatcgta gggatgaaac ctacttatgg
    10801 ccgtgtctca cgttttggtt tgattgcctt tgcttcatct cttgaccaaa tcggaccaat
    10861 gacccgtacg gtgaaagata atgcattagc attgacagct atcagcggtt atgacgaaaa
    10921 agacggtact tcttcaggcg tttcagttcc tgattttgca gagggactga caggcgacat
    10981 caaaggaatg aagattgctt tacctaaaga atacttaggc gaaggtgtgg cccctggcgt
    11041 aaaagaagct gtattgaaag cagcagaaac attccgttca ttaggtgctg ttgtggaaga
    11101 agtcagcttg cctcattcaa aatacggtgt ggctgtttat tatatcattg cctcatcaga
    11161 agcaagttcc aatttgcaac gattcgatgg tatccgctac ggttatcgct ctgaaaatgt
    11221 gaaatcatta gatgatgtat atgtcaactc acgttcagaa ggattcggtg aagaagtaaa
    11281 acgccgtatc atgttaggta cattctcctt aagcgcgggt tattatgacg cttacttcaa
    11341 aaaagcagga caagtccgta cattgatcaa acgagatttt gaaaaagtct ttgcagatta
    11401 tgacttgatc atcgggccat cttcaccaac agttgcattc ggaatcggtg agaacattaa
    11461 cgatccaatc acaatgtaca tgagtgacat cttaacgatc cctgtcaact tggctggact
    11521 tccaggtatg tctgtaccgg caggtttatc agaaggatta ccagttggat tgcagatcat
    11581 cggtaattat tttgatgaaa aaacgatgta tcaagcggca tatgcgtttg aacaagcaac
    11641 agaattccat aaacaacaac cagctatttt aggagggaaa gacgaatgaa ttttgaaaca
    11701 gtcattggac tagaagtcca cgtcgagtta aaaaccaact caaaaatttt ctctccagcg
    11761 ccagctcatt ttggtgcaga accaaacagc aatacaaacg tgatcgactg gggttatcca
    11821 ggcgtgctgc cagtaatgaa taaagctgcg ctggaattcg ggatgaaagc agctttggca
    11881 ttaaactgtg aaatctctaa agatactcat tttgaccgga aaaattactt ttacccagat
    11941 aatccaaaag catatcaaat ttcccaattt gatcaaccaa tcggtcatga cggatggatc
    12001 gaaatcgaag tagaaggtaa aaagaaaaaa atccggatcg aacgtgtcca tttagaagaa
    12061 gatgctggaa aaaacatgca tggtattggc ggttattctt acgttgattt gaaccgacaa
    12121 ggcacgcctt tgatcgaaat cgtttctgaa gctgatatgc gttcaccaga agaagcatac
    12181 gcttatctag aagcattgcg atcaattatc caatttacag aagtcagcga tgtgaaaatg
    12241 gaagaaggct ctatgcgctg tgatgccaat atttctcttc gcccttatgg acaagaagag
    12301 ttcggtacga aagcagaatt gaaaaacttg aactctttat ctttcgtgaa aaaaggttta
    12361 gcttttgaag aaaaacgtca agcaaaagtt cttctttcag gaggagaaat ccaacaagaa
    12421 acacgccgtt ttgacgaaac aacgaataaa acagttttga tgcgtgtcaa agaagggtct
    12481 agtgattatc gttacttccc agagcctgat atcccgaaat tcgtgatcga tgacgaatgg
    12541 attcaaaaag taaaagctag tttgcctgag atgccagctt ctcgtcgcga acgctatatc
    12601 cgtgagtttg gacttccaga gtatgacgca atggtattga cacttacaaa agaaatgtct
    12661 gatttttttg aagctgtttt ggaaaatggt gcagatgcca agcaagcatc taactggttg
    12721 atgggtgaag tttctgctta cttgaacagt gagaaactgg aattagctga gacaaaattg
    12781 acacctgaga acttagcagg aatgattcgt ttgatcgccg atggaacgat cagctcaaaa
    12841 atcgccaaaa aagtcttccg tgaattgatc acaaatggcg gagaagccca agaagtagtt
    12901 gaaaaaaatg gttgggtgca attatctgat ccgaacaaac tactgccaat cattaatgaa
    12961 attttggata acaaccaaca atctgtcgat gatttcaaaa atggaaaaga tcgtgcggtt
    13021 ggcttcctag tcggtcaaat catgaaagca actaaaggac aagcaaatcc tggtgtcgtg
    13081 aataagctac ttaaagatga attagcgaaa cgatagaggc tgaaaatgaa aaaagcacgc
    13141 gtaatttata accccacctc gggaaaagaa ttattgaaaa aaaatttggc ggatatccta
    13201 caggcattag aagaagcagg atttgaagcc agcgcctatg caactacacc agaaccagat
    13261 tcagccaaga atgaagcatg tagagtcgca gaactaggtt ttgatctagt agtggcagct
    13321 ggtggcgatg gcacaatcaa cgaagtggtt aatggaatcg ctccgcttga acaccgtcct
    13381 aaaatggcca tcatcccagc tggtacaacg aacgactatg ctcgagcatt aaaaattcct
    13441 agagataata ttaaagcagc agcagaagtg ataaaaaaac accaaaccgt aaaaatggac
    13501 atcggccttt ctgataacag ttacttcatc aatatcgctg caggtggcta tttgacagaa
    13561 ttgacttatg aagttccatc agaactaaag agtatttttg gttatcttgc ttatcttgcg
    13621 aaaggagcag agatgctccc tcgagtaaag ccaatcaaaa tgcgcttgaa gtatgatgaa
    13681 ggggaatata tcggaaatgc ttcgatgttt ttcctagggc tgacgaactc tgttggagga
    13741 ttcgaacaga tcgcgccaga tgccaaattg gatgatggga agttttcttt aatcattgtg
    13801 aagacagcaa atatctttga gatcttgcat attgcagcac tcatgctgaa tggcggtcga
    13861 catgccgatg atccaagaat aatctatacc aaaacaagca gtttgttcgt tgaaacagaa
    13921 gatgatatca atcgaccagt aatgatcaac ttagatggtg aatacggcgg ggaagcaccg
    13981 atgcatttcc aaaatcttca tcaacacatt gagttctttg ccaataccga tcagattcct
    14041 gatgaagcaa tcacaggtac agatgaagaa gaattagagg ttgtcagcaa agaattcgta
    14101 aaagaagtcg aacgtttaac ggatgaagat atcgacggtg acggaaaaat agcagacgaa
    14161 acacctaatc aaaagaatta atcaaaagcc ggtgctgaac gtagtaaggt cagtgccggt
    14221 tttagttgtg taattagctg atttatagta gagttcagta ggattgaaaa ataggcttaa
    14281 aggagcaaaa tatgacagaa cagcaaatag taaagaaaaa cgaacgatat acagtcgaaa
    14341 tcgtcgactt gagttatgaa ggaatggggg tagcaaaaat cgatggttat ccattattta
    14401 tcgaaaatgc actccctgga gaagaagtag aaatactagt agtaaaagca ggcaataagt
    14461 ttggatatgg aaaagtcgaa acatttatta cacaatcacc tgatcgtcag cctgtagaaa
    14521 acaatgcatt acttcgcata ggtatcgcac ctttagccca tttgaagtat gaacaacagc
    14581 ttgtcttcaa acaaaaacaa gtagagcatg taatggcgaa gattgctaag atgccagaag
    14641 ttcctgtact tccaacggtc ggaatggcag aaccattcgg ctaccgtaat aaagcacaga
    14701 tccctgttcg ccgtatcgat ggacagttag ccaccggttt ttacaaaaag aatagccatg
    14761 atctagtccc tatcgaagat ttttatatcc aagatcctgt catcgatcaa gcaatcaaag
    14821 tagtcagaga tatcttgcaa cggttccaag tacgaggata taatgaagaa aaaaatgaag
    14881 gacagcttcg tcacatcatt atccgtcgtg gtcattattc ccatgaaatg atggtcgttt
    14941 tagttactcg taaagaaaaa ttctttaaat ccaaggaaat tgctgaagct attcatgaag
    15001 aattgccaga agtggtttcg gtcatccaaa atatcaatga agaaaaaaca aatgtgattt
    15061 taggagacaa agaaaaagtt ttatatggca gagactatat cgaagatcag ctattaggaa
    15121 aaacctatcg aatctcagca aagtcatttt atcaagtaaa tactcaacaa gcagagtatc
    15181 tgtaccaaac agccatcgag tttgccgagt tagataaaaa agacattgtg atcgacgctt
    15241 attcaggaat aggtacgatt ggcttgtctt tagcagacag agtggataag gtgtatggga
    15301 tggaagttat tccagaagca attgaagatg cacagttcaa tgctttaaat aataaaatcg
    15361 aaaatgttca ttatgaagtc ggaaaagcag aaaaagttat gaaaaaatgg caagaaaaag
    15421 ggatcaaacc atctgtgatc gtagttgacc ctccacgaaa aggattagat catcatttta
    15481 ttgaatcagc aatcgaaatg tcaccagaac gaatcgtcta tatctcatgt aatccggcaa
    15541 cttttgcaag agatgctaag ttatttgcag aagcaggtta tgccgtgaag aaagttcagc
    15601 ctgtagatct tttcccgcaa acccatcata tcgaattagt cgcttcattc gttaaaggag
    15661 aataaaaatg gaccaaaaag aaaaaatgaa agaattgatc aaaaagaaac aaggtggagg
    15721 ccgatccaaa caaatggaaa cacctaagaa tgatcgtaaa aacatgagaa aaggccctaa
    15781 aatctttaat aaatagacgt gctaaagaaa gactaagaag tgttaacttt tgttattgtt
    15841 tcttagtctt tttagttagt ctacattatt ttggcgattt gccaataagg actgttgagt
    15901 tgtgcaaaat caaatctggg tcagaatgaa cgtcattctg tctcagattt ttcgttattt
    15961 caatttgatt aactgattga tcaaaaagat ttttattttc atattctcaa atgattcaac
    16021 actaaatata catgtttgac gcggaaatta ttattcgatt ttggcggcat caggggggat
    16081 gacgacgtag cagacccatt attttactca agaaaatgtc cgtgcctatt atttagaata
    16141 cgatagtgaa cgtgctggga gttttgttct tttagagaaa gtctctgaag ataaattagt
    16201 tgtcttagat tttgactgta acgaaaaatg gcgaaatgga agagcaccag caagtgattg
    16261 accggatcta cgaagcgaca cgatatctgc ctttggatcg tttgtgctta agtcctcaat
    16321 gtggatttgc ttcaacagaa gaagaaaatg ttttgtttga agaacaatgg aaaaaatttc
    16381 ttttgtcaaa agcattgcag aagaagtttg gggaaaatca ttaaatcatc taggagagct
    16441 tgataggaaa taacactatg gtataatcag aatgcttaat actaactact gagggagcct
    16501 tatgaaaaag aaaattctta aatttatcgg atggttcttc ggaatcattc ttgggatcgc
    16561 gtttgcaatc tttcttgcct tccagctttc ccccagacct ggagcattct tgatcaacca
    16621 tatgttttca aatactgttc aaatcactga taaaaaaacg ttcgatcaag cagaaaaaaa
    16681 cgtggcgaaa aaaacagatt tgacgtatga gtccaagtat aaagagaata cttatgacat
    16741 ctactatcca aaaaacagca aggggcctgt tcctgttcta ttttgggtac atggtggagg
    16801 attcgtcggc ggagataaat cgggtgtcaa agaatttgcg acaaaattag tttcagacgc
    16861 caacatcgca gtggttgcga tgaattatga attagcgcct gattcagaat accctaatca
    16921 agttcttcaa gtgaatgaac tgatcaaaga tttattagct gaagaaaaag acgacaaatt
    16981 gctagacatg gaacaattat tttttggtgg agatagtgca ggttcacaaa tcgcattgca
    17041 atatgcagct atacaaacga atgatgcgta tgctaaacaa atgaaaatca aacatctact
    17101 tccaaaagat agtctgaaag gaaccatttc ttattgcgga cctgttgatt tgaagctaac
    17161 agcacagcag cattcggatg atcgatttat gaagtttttc gtcaaaaccg ttgcgtggtc
    17221 gttgattgga acaaaagatt ggaaaacgag tgagcaattg aaagaagcta gtgtggctga
    17281 ccatgtttct aaggaatttc cgccaacgta tataactgac ggaaatgcat actcattcca
    17341 ggagcaaggt caagcattag aaaatcggtt gacagaatta aaggtacccg tgcaatcctt
    17401 gttttataca gatacaaaaa aagagattac ccatgaatac caatttgatt acacgctaaa
    17461 agaatcgcaa aattgttacc agcagacatt ggattttgtg aataagtata agtaagaggt
    17521 tgtgaaaaag ccgtttcgtt ttgagtatga agaaacgaag cggcttttca caacctctct
    17581 ttcaatacct ttttgttctt gggataaaac tttccctaac aatcaatcgt gcaggataag
    17641 tcaaaatgat tggttcgtcc cgtataccgt caattcgctc caatgccatt cgaacagctg
    17701 cttgcccaat tgatttcgca ttgatttgaa cactggtcaa gccaggggag aggtttgcga
    17761 ttgtctcgat attatcaaag cttgctacaa caatctcttc tccaatttgg atattttttt
    17821 gtttcaatgc ccgatagaca ccaattgcca ttggatcgct cccgacaaga atggcagtag
    17881 gaagagggga ttcattttct aatagattag tcgcaagtac ctcaccttgt ttttctgtcc
    17941 agccacctag atgataagac atatattttt ctaagtgatg atcgatcata aaatgctgat
    18001 aggcacgcat cctcttttca tttatagaaa tctgcttccc accgaattca tccatatcga
    18061 ctttatatcc cccgatatag gctattcttt tatgaccatt ttctaagaac aattccagta
    18121 cggttttagt catccgttca agatctgcat acaccatatc gacctcttgc tggatgtcag
    18181 ggttatccac gacgactatt tgcatgtttt gttttaacaa ggcggtaatc gattctttcg
    18241 taacagtccc aacaacgatc accgcaccta actgatctag atcttcccat tgtttaggat
    18301 tatcagatag attatagatt cgattcatcc ctaaatgcag acgtcgagct tcttcttcca
    18361 tccctactcg caaatgtttg taatagatat cctgttcttc gctcgctttg ccgatcgtag
    18421 agatcacacc aatcgaaggc attctctttt tgatatattt acgagtactg atgtcataat
    18481 ccaacgcagc agctgcctct actatccgtt gccgagtagt ctgagccaca tggatcgtct
    18541 gatcgttatt caacacacgg gaaactgtag caggagagac atttgccttt cgtgcgacat
    18601 ctctaattcc aaccattttt acacactcct caaaaaaata aaaaattttt attgacaaaa
    18661 ttgtttagta aacagtatac aggaattata aaaaaaagta aacggtttcc gttttgttgg
    18721 gagtgaaatg atggatatta cgcatagaaa aacagataaa aatttcatct tatttgatga
    18781 aaagagccga gtcttccatt tacgaaatac atttctttct tatctgataa agatagaaga
    18841 aagcaatgta ttggcgcata tttattttgg caaaccagtc aagcagtaca aagacaataa
    18901 aaattatccc cgaagagatc gtggattttc aggaaatgtt cccttaaatc ctgaccggtc
    18961 tctgtcgaaa gatacactac cgcaagaata ctcttctcat ggcagcatgg actttcgaac
    19021 gcccgcatcg atcattcagc gcaagaatgg atcagactta ctggatctga gatatgacag
    19081 ccattatatt acagatggga agccagagat cgaaggcttg cctcaaactt atgtgatgga
    19141 caagtcagag gcacaaacgt tggtgatttc acttaaggat agagaaacag cgatttattt
    19201 cgatttgttc tataccatat ttactgatag agcagtgatc acacgatctg taaagataag
    19261 aaatgaaacc ggagaaacaa tcaaactaga aaaagcggct agtttccagc tagactttgc
    19321 ccatactagg cgatttgatg aagtcattgc tttgccagga gcacatgtca atgaaagaca
    19381 gatttcacgg caatctgttt tatctggaac aaaagtattt gaaagccgtc gaggaacgag
    19441 cagtcaccat atgaataact ttattgcttt agttcatcat catacgacag aaaatactgg
    19501 agaagcgatc ggacttcaat ttgtttattc cggcaaccat tctttcgaac ttgaaaaaga
    19561 tcagatcaat caattgagag tcgtcggtgg gatcaacagc catcgttttt cgtgggaatt
    19621 gaatgcaggc cagtcttttc aaacacctga aatgatcctt tcttactcaa gtcagggatt
    19681 gaacaaaatg agtcagatcc accatgagtt gctacgtgaa agaatcgcaa gaggtcgtca
    19741 tcaatttgct gaacggccga ttctggtcaa taactgggaa gccacttact ttgacttcaa
    19801 tagtgaaaaa atcaaggcga tcattgatga agcaaaggag ctaggcatcg aaatgttcgt
    19861 attagatgat ggctggtttg gaaaaagaga tgcggacaat tcttcattag gagactggtt
    19921 cgagtatgaa ggcaagttga caaatggatt acgtgaaata gcagattatg ctcatagcaa
    19981 aggattgaaa tttggtttat ggtttgaacc tgaaatgatc tcggttgatt ctgaactgta
    20041 tcgaacacat cctgattttc ttatgcagga gccaggtaga atgccttctg cttccagatc
    20101 acaacatgta ctggatttta caaggttaga tgttcggcag acgattgaga aacaaatgag
    20161 aaagatttta gatacgattc ctcttgacta catcaaatgg gatatgaacc gttcgctttc
    20221 agatgtctat tcgattaccc ttgacccaca gagacaagga gaagtagcgc atcgttatat
    20281 gctcgggctt tatgaactac ttgaacattt gacaactgat tatccggaaa tcttatggga
    20341 aggctgttct ggtggaggtg gacggtttga tgccgggttt atttattata tgccgcagtc
    20401 atggacaagt gataacacgg atgcagtgga gcgtatgaaa atccaatatg gaacaagcct
    20461 tgcttatccg atttcgtcca tcacagctca tgtatcagct gtaccaaatc atcagaccga
    20521 cagatctact tcgttgaaaa caagaggaga aacagctatg agcgctgttt ttggttatga
    20581 actggatttg acaaagctgt ctcctgaaga agaaaagcaa gtaaaagacc aaattatatc
    20641 ctatcaaacg attcgtccgg tgatccagta tggccattat tatcgtttgg cgagtccttt
    20701 tgaagaaaat attgccgcat ggatgtttgt gtctcctaaa caagatgaag ctattgtgtt
    20761 tttagggagg atactagctt cagctcaacc agcgttccat gaagtatatc tgatggggtt
    20821 agatgatgag gcactttatc aggaacagac ctcgaagcgg atattttcgg gggccgaatt
    20881 gatgacagtt ggactttact tccccgattt tcaaggtgat ttccaaacag aactgcttca
    20941 tttcaaaaag ttatgagaga gaaggaaaaa agtatgaaag caaatataaa atggttagat
    21001 gatccacaag tttttagagt gaaccaatca aatgcacata gcgatcatgt ttgttatgca
    21061 acaagggaag aagtagaaac cacatcctcc cttaaacagt ctttaaatgg atcatggcgt
    21121 ttttgttatt cgccaaatcc ttcggtacga ccaaaaacat tttataaaaa agattttgat
    21181 gcctgttctt ttgatgaaat cactgttcct agtcatattg aattagcaaa ttatgacaag
    21241 atccattaca tcaatacgat gtatccgtgg gagggacatg tatttcgccg tccccctttc
    21301 acgacaagcc ctgagaaaga ggcggaaggg atcttttcag ctgctaaaga caatccggtt
    21361 ggttcgtatt tgacgacttt tcgattagaa gaaggtctaa agggaaaaca aatctcgatt
    21421 cattttgctg gtgtagaaca agcaatgttt atttggttga atggtcattt tatcgggtat
    21481 gccgaagatt cgttcactcc gtctgaattt gatttaacac cttatttgga agaagaaaat
    21541 attctagctg tggaggttta caaaagaagt acagctgcat tcttggaaga tcaggacttt
    21601 ttccgatttt ttgggatctt cagagatgtc ttcttagttg ctcgaggaca aaaccattta
    21661 gaagatcttt ggatcaaacc tcgcttagat gacaaatgtc aaaatggcaa acttgaagta
    21721 gatttgtctt ttgagcaagt agccaaaaac agtcagctga atgtagcgat actagatcct
    21781 gatgggaagg aaatctatca acagcaatat ccgttaaaag agcaaatgac gattcgcatc
    21841 gatggatttg aaaatgtggc actgtggggg cattttcagc ccaatttata taagcttgaa
    21901 ttggagacga tagacgaaga aaaaagagta acggagtata ttgactattc cttcggtttt
    21961 cgtaaaatcg aaatcaaaga taaaatcatc tacttcaatg gaaaacggat gattatcaac
    22021 ggggtaaatc gacatgagtg gcatccgaaa aaaggacgcg ccatcactat agaagatatg
    22081 gaaaaagatt tggctatcat aaaaaatgca aagatcaacg gcgtacggac atctcattac
    22141 cccaaccaga tcacttggta ttatttatgc gaccaagcag gaatccatgt gatggcggaa
    22201 acgaacctcg aatcccatgg ctcatggcaa aaaatgggcg catttgagcc ttcttacaac
    22261 gtaccaggtg cagtacctca gtggcaggcg gctgttcttg atcgagcaaa aacgaatttc
    22321 gaaacattaa aaaaccatcc aagtattctt ttttggtctc ttggaaatga atcttatgcg
    22381 gaagaaaaca ttcgacaaat gaacgattac ttcaaaaaag tagaccccga tcgacttgtc
    22441 cattatgaag ggaattttcc aaatccagca ttcgaagatt cgatttcaga tgtaaaaagc
    22501 tgcatgtatg cgccaccaga agagatcatt gactaccttg aaaataaagc ggaaaaaccg
    22561 ttcatcttat gtgaatatat gcatgacatg gggaattcgt taggtggaat ggattcttac
    22621 atgacgttgc ttgatcgtta tgaaatgtac caaggaggct atatatggga ttttaaagat
    22681 caggcgatcc aagtgactga tccaatcaca ggcagagaag tgatgcgcta tggcggtgac
    22741 tttgacgata aaccaagtga ctatgaattc tcagggaatg ggatcgtttt tgcagatgga
    22801 caagaaaaac ccgccatgca ggaggtaaga tattattatg aaaaatacag taaataaaag
    22861 tcatatggat acggaaaaag ttgcaatcgt cttcggcgac tgtacattag gtgtcaaatc
    22921 ggggaatacg cattatattt tttcttatac aagaggcgga ctggaatcgc tcaataaaaa
    22981 cggaaaagaa tggctatacc gggaaacact tccagttttt tggcgagcaa cgaccgataa
    23041 tgacagaggt agcggatttg gatttaaatc cggtatgtgg ttaggagccg gattgtatcc
    23101 aaaagtcaaa gaaatagaag tactggtgga caataaaaag atcgatttgc cgattgctcc
    23161 agtaaataat caatattcaa gtaatgaata cgctgaaacg gttgaaatca tttttacact
    23221 ggaaatcaac acagtaccaa aaacccaagt gacaatttcc taccaaatcg ctggagaggg
    23281 taaaatgctt gtcaatatgc attattatgg acaaaaagga ttaccggaat tacccgcatt
    23341 gggtttaagg ttcattatgc caacgaaagc aaaatttttt gagtatgaag gcctatcagg
    23401 ggaaacatat ccggatcgga tggctggtgg tgtcgaaggt atttataaag tggcaggact
    23461 ccccgtttcc ccataccttg ttccccaaga atgcggcatg catatggaaa cgaaatgggt
    23521 agaactaaca agaaatcaaa cgttggataa tacggataaa gatcaagaag atttttcgtt
    23581 gcgatttgaa cagcaggata cgccatttgc tttttccgct ttaccattca aagcagaaga
    23641 actggaacag gcaacacata tagaagaact accgccagaa agacgaacgg ttcttacgat
    23701 ttttgcaaaa gtaagaggag tcgggggtat caatagctgg ggagcggatg ttgagtcacc
    23761 ttaccgaatc agcagcgaag aggaccatga aatcggcttt attattcagt agcaatcttt
    23821 agattattat ttgaaaaacg gagtttacaa gacaaagctg ctttattcta tatgtcatga
    23881 acaagagagt aaaaaagttc tcagatactt ttgttcatga ctattttctt caataaaacc
    23941 aattgttatt tttctgaaaa acaaagttaa ctatcagaaa attaaaaaaa gtttcataaa
    24001 aatgattgac agtcgatttt tttatgtcta tactaggtac aattcttaca tcagtttgga
    24061 gcgatttttt atgaaatcta gaaaacttac aaaactgaat acgtattact ttagctattt
    24121 tagataggtt tgtattcatg acttcgtggg tacaaacaaa ccaggtttgt atctatgatg
    24181 gctaaagatt tttaaacacg acttacagcc acgtagagaa attcatctat agtggctatt
    24241 ttatattttt gcagcgcttt ttaaggctcg ttgaagatgt tcactgtaga ggcaatttcc
    24301 tacagggaca tctttttttg ttgattatct gggtcataag taggaaagaa ggagcgaaaa
    24361 tgagaacaac aggacacggt catttagtag gaattaatgt aaaaccacct tgaaaaagta
    24421 gagaaaatca gccaagatag ataagtaaac aaaagaaagc gggaaaaaca atgatagtaa
    24481 ttatgaaaaa agaagcaacg gaagaacaaa taaaaaaagt cgtcgatcat atcgaaaaag
    24541 aaggattcaa agtctcaatc gatcaaggaa cagaacgagt agtgattgga ctaaaaggtg
    24601 atacgcgaag tttacaagaa ggagcattta cacgctatga aggagtagaa aatgctgtgc
    24661 gtattttaaa cacatacaaa ttgacttctc gagaattcca tcctggcaat acagtcgtgg
    24721 atgtagacgg agtaaaaatt ggtgacggca gtttcgtgac gatggctggt ccttgttcta
    24781 tcgaaggatt agaccaaatc agagaatgtg cgcgaatggc caaagccggg ggcgcaaaaa
    24841 ttctgcgagg tggtgccttc aaaccacgta cttctccata tgctttccaa ggtttagaag
    24901 aagaaggatt gaaatacatc cgtcaagcgg ctgatgaatt tggaatgaaa gtgattactg
    24961 aagtgatgga tgaagggcat atcgatatgg tggctgagta cagcgatatc ctacagattg
    25021 gcgcacgtaa tatgcaaaat tttaaactgc tatctgctgt cggtaaaaca ggtaaacctg
    25081 ttggattgaa acgtggaatt tccggtacga tcaatgaatg gcttaatgct gcagaataca
    25141 ttgcagtcga agacaaatct cctgtcattt ttatcgaacg tgggattcgg acttacgaaa
    25201 cagcgacacg taatacgttt gatttaagtg ctgtcccatt gatgaaaaaa ttaactcatt
    25261 tccctgtgat tgttgatcca agtcatggta caggaatttg ggaacttgta ccaccaatgg
    25321 ctcgtgcggg tgtggcaagc ggagcagatg gcatgatcgt agagatccat cctgatcctg
    25381 caaatgcttg gtcagacggt ccccaatcgt tgaatgaaaa gacttactca cgcatgatga
    25441 aagaagttgc gatcatgaaa gaagcaatgg aaaagattca gacactcgat taattccagc
    25501 tttttaaaag aaagaagtga aacgaatgct tactgtacat gttgataacc aaaaatacga
    25561 tattcatatt gaaaaaggcg cactagaaca ggctggatca tggcttcaaa cgatttggag
    25621 acctcaaaaa gtagctgtga tcactgatac aaacgttgct ccactatatg cagaaaaaat
    25681 catgttccaa ttgagacaag ctaattttga accagtcctt tcaatcgtac cggcgggtga
    25741 gaccagtaaa tctttagaac aagcagctga gttatacgat tttttagcag ataatgattt
    25801 tacccgcagc gatgggatac ttgcacttgg tggaggaatg gtgggtgatc tagcagcatt
    25861 cgtggcctcg acgttcatgc gtgggatcca tttcgttcaa attccgacta cgctacttgc
    25921 acaagtagat tctagtattg gcgggaagac agcagtcaat acaaacaaag cgaaaaacct
    25981 tgtcggaaca tttagccagc cagctggtgt attgattgat cctgaggttc taaaaacttt
    26041 gccggtacgt cgtttacgag aaggaatcgc tgaaatcatc aaatcagcag ctatagcaga
    26101 tgcaacgctt tggaaacagc tgaacgagct gaaagacgaa aaagatcttc tggaacatgc
    26161 tgttccaatc attactgcta cgttggaaat caaacgaaaa gtagtggaag aagatgtctt
    26221 tgaccaagga aatcgactta ttttaaattt tggtcataca attggccatg caattgaaaa
    26281 tacagcagga tatggggtag tcagtcatgg agaaggagta gctattggaa tggtagccat
    26341 cacttctcat gcagaaaaaa tcggcttgtc tccaactgga tcgacagctg ctttagaaag
    26401 gatacttcaa aaattccatc tgccgattac gtacgatcta agtcatccag atgaattatt
    26461 ccacgcgata acccatgata agaaagcaag aggaagccaa ttgaatatca tcttgctaga
    26521 aaagattggg caagcaaaaa tcgttcctgt tcccacagag acattcaaag attacttagg
    26581 aggactgtaa gatgcgttat atgactgcgg gagaatccca tggaccagaa ttaacagcca
    26641 ttattgaagg actaccagca ggattacctc tgtcagaaga agaaatcaat cacgaactcg
    26701 ctcgcagaca agctggttac ggcagaggag gaaggatgaa gatcgaaaaa gatcgtgttc
    26761 ggatcacgtc tggcatccgt cacggcaaaa caattggttc acctgtcact ttagtggtag
    26821 aaaataaaga ttggaaaaat tggacaactg tcatgtctgt agcagaagtg cctgaaaaag
    26881 accaatcact gcggcgagtt gcacgtccgc gtccaggaca cgcggatttg gtaggcggta
    26941 tgaaatacca tcatcgagat cttcggaatg tgcttgaacg gtcctctgca agagagacga
    27001 ccatgcgtgt agcaatcggc gcaattgcca agaaaattct ggaagaactt gacatcatcg
    27061 tagcaggaca cgtgatttgt cttggtggaa tccaagcaga aatacctgga aatatctcga
    27121 ttcaagaaat caaagaaatt tctgaagcgt cagaagtacg agttgttgat ccagcagttg
    27181 agcaaagaat aaaagatttg atcgatcaga caaagaaaaa tggagatacg atcggaggaa
    27241 ttgtagaagt gctcgttgga ggcgttccag ctggattagg aagctacgta caatgggaca
    27301 cgaagctaga tgccaaaatc gcacaagctg tggttagtat caatgccttt aaaggcgtag
    27361 aatttggggt cggattcact tctggttcat taccaggctc agaagtgatg gatgagatcc
    27421 tatgggaaga agaaagaggc tatttccgac gtaccaataa tctaggcggc ttcgaaggcg
    27481 gaatgaccaa tggcgaacca cttgtcattc gcggggtcat gaaacccatt cctacattgt
    27541 acaagccact tcaaagtgtt gatatcgata caaaagaacc ttacaaagca agtgtagaac
    27601 gttcggatag tacagcagtt cctgcagcta gcgtcgttgc ggaaaatgtt gtagccactg
    27661 tggtagcgac agagctattg tcaaaattcc caagtgattc gcttgttgag ttgaaagctg
    27721 cagtgaagga gtaccgtgac tacttgaaac attactaaaa agggggcaaa taagatggca
    27781 caacatgttt ttatcgtggg gcttggactg attggtgctt ctatggcact ttgtattcgt
    27841 cagaccaatc cagaactgat agtagttggt tgggatagtc agtcaaaaac ccgtgagcaa
    27901 gcagtagaac agcagatcgt tgattacgtt gcaagtgatt ttgaaacagg tgcagaacaa
    27961 gcagacgtta tcttattagc cgttcccgtc cgtacaacct tagcttatct tgatgtcctt
    28021 gaaagaatca acttgtctga tcacgtcatc attacggatg tcagcagtac gaagcagcaa
    28081 gtcgtgacat ccgctgagca gaaaaatctt cggtttgtcg gtggacatcc aatggctggt
    28141 tctcataaat caggtataca ggcagcagat gctaaactat ttgaaaatgc ctattacatc
    28201 tttacacctt tggaaaagac gaaaaaagat gttgaaaaac tgcaagaact attttgcgga
    28261 accaaagcaa aatatgtaac tcttacagca agagaacatg accgtataac aggaatgcta
    28321 agtcattttc cacatattct ggcagctggc ttagtcaatc aggcagaaca attcaatcaa
    28381 gagtatccgc gagccaaaca actggcagca ggaggctttc gagatatcac taggatcgct
    28441 tcctcagatc ctgtcatgtg gacagatatt ttgttgagca ataagcagat attattggaa
    28501 cgattggcag attggcaaca agaaatgaca caaatagcag aatggatcat gactgagaac
    28561 caatcggaaa tcttttcttt tttcaatcgg gcaaaagaaa gtcgagacca gttgcctgtc
    28621 cataagcaag gcgcgattcc tgcctttttt gatttattta tcgatgtgcc agatgaacct
    28681 ggcgttattg cagaagtaac tggactgatc ggaaaagcgg gagtttcttt gattaatttg
    28741 aagatccaag agaccaggga agatatttta ggaatactgc aaatcagttt taaaaaccaa
    28801 caggatttgt tacaagcaaa aagaatcatt atgtctaata ccagttatca ttgctggatc
    28861 aaataggagg ctggataaat gcaattatta caacaaatac atggattaag agggactgtt
    28921 aggataccag cagataaatc aatttcccat cgcagcatca tgtttggagc aattgctgaa
    28981 ggaacgacga ctatacaaaa ttttttgcgc gcagaagatt gtctgagtac tttacatgcc
    29041 ttccaacaat taggtgtcga gatcgaagaa gaggaagagg tgatcaagat tcatggtcgc
    29101 ggtagccact catttgtcca accaaccgaa tcaattgaca tgggaaactc cggtacgacc
    29161 atacgtttat tgatgggtat tttggctgga cagcctttta cgactactct gttcggggat
    29221 gcttcgttgt ctaaacgtcc aatggggcga gtgatggaac ctttacgcga gatcggcgct
    29281 gacttgcaag gagaagaaaa tgaccagtat ctaccaatca ctgtgacagg aacccgctct
    29341 ttatcaccta tccgatacaa tatgcctgta gccagtgcgc aagtcaaatc tgctttgctg
    29401 tttgcggcat tacaagcaga aggcacatcc gtaatcgttg aaaaagaacg ttcccgtaac
    29461 catacggaag aaatgattcg tcaatttggc ggaaggatca cagtggaaga taaaacgatc
    29521 atagtgaccg gaccgcaaaa attaactggt caacagataa ctgttccagg tgatatttca
    29581 tcagctgctt tctttctagc agcaggactt cttgttccgg aaagccaact gttgttaaaa
    29641 aatgtcgggg tcaatccaac aagaactggt atcttagatg tgttggagga gatgggcgca
    29701 gcgattaccc agacgaatca caatgaacag aaccaatcgg ctgatttaag tgtcaagacg
    29761 agtcatttga agaaagcaac gattggtgga gaaatcattc cgcgtctgat tgatgaattg
    29821 cccattctag ctttagtggc tactcaagca gaaggaatca cgatcatcaa agacgcagaa
    29881 gaattaaaag taaaagaaac caacagaatt gatgcggtgg cagaagaatt acagaaaatg
    29941 ggagcaaaga taaaagcgac agcagacggt ctgatcatcc atgggccgac acctctgcat
    30001 ggcgcaaaag tgtccagcag aggcgatcat cgaatcggta tgatgctgca agtagctgct
    30061 ttgatagctg atggaccttg cgaactagaa ggagctgaag ctgtttcaat ctcttatccg
    30121 gcattttttg acgatttagc agaacttgtg tcaggaggag aagctcatgg ctagcatttt
    30181 gctgattggt ttcatgggcg ctggaaaaac aacaatcggt aaagggttag ctcaatgttt
    30241 acaaaaagag tatgtagatt tagatacaaa gattgaggaa catatccaat tgtcgattgc
    30301 cgaatatttt cactattacg gtgaaaaaag ctttcgaaaa gtggagtcag atattttaag
    30361 aaagctgtca aatgaagaca aaattatcgc gactggtgga gggattgtcc aaagtgcaga
    30421 aaatcggcgt tttttaaaaa cacagccgat tgttctttac ttagaggcag aagcggactg
    30481 tctagttgat cgtatccaac aagatgaaac gtctattcga cctttagctc ttggaaaaac
    30541 aagagaagaa ataaaagcat tattggcaca acgactttct tggtatgaag aaagtgcgac
    30601 acatcgaatc aacacgacca atcaaacacc agaaaagatc atcgatacca ttatagaaag
    30661 gatcaaaagc atatgaacgt cagctatcta gggccagaaa gttcattcac ttatcaggcg
    30721 gcttgtcagc tatttcctac agaacaattg actgcgtatg cttccatccc tgtttgtttg
    30781 cgcgctttgt ttcgcaaaca agtcgatctg gctgtcgttc ctgtagagaa ttcattggaa
    30841 ggagctgttc atcacacaat cgatcttctt tccaaacatc cagaagtcga agttaaaagt
    30901 gaaatcgttc ttcctatcaa gcagcagctt ttaggcaatc cagcaacaaa gattacaaaa
    30961 atcctttcac atccacaagc actagcacaa tcacaacagt ttttagaaac gcattatcct
    31021 aatgttcctt tagtagcaac agaatcaaca actgctgcag caatgtatgt agcagaacat
    31081 ccgaaagaag acgcagcagc gattgcttca ttagaaacag cacagcatgt tggattggag
    31141 atcttagctg agaatatcca agataatgag ttgaaccaga cacgtttttg gatcgtcggt
    31201 gaccgaaaga tgaccagcca gcagtcagct ccagtaaaaa tgagtgtcat cttgacacta
    31261 cctgctaatc ggccagggat gcttcataaa atgctggcag cttttggctg gcgggaaatc
    31321 aacttaagta agattgaatc ccgaccattg aaaactagct tgggagaata ttttttcgtg
    31381 atcgatttgt tgttggaccg tccaatgaca ttagtagaga atgcgctcca agaaatcaag
    31441 atgctcggag gagaaagtca aatattgggc tgttatccag tgctgacagt agaagagacg
    31501 cgtagatgaa agtcaagaat actgattgat ttatttaact ta
//
LOCUS       DAXLPY010000025        30911 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.025, whole genome shotgun sequence.
ACCESSION   DAXLPY010000025 DAXLPY010000000
VERSION     DAXLPY010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.025"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            25..696
                     /locus_tag="ACF3UF_001286"
     CDS             25..696
                     /locus_tag="ACF3UF_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3671428.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="ACF3UF_001287"
     CDS             755..1195
                     /locus_tag="ACF3UF_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671429.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="ACF3UF_001288"
     CDS             1207..1875
                     /locus_tag="ACF3UF_001288"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFD3671430.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="ACF3UF_001289"
     CDS             1939..2562
                     /locus_tag="ACF3UF_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFD3671431.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="ACF3UF_001290"
     CDS             2618..3004
                     /locus_tag="ACF3UF_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFD3671432.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="ACF3UF_001291"
     CDS             3217..4608
                     /locus_tag="ACF3UF_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFD3671433.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5219..5587
                     /locus_tag="ACF3UF_001292"
     CDS             5219..5587
                     /locus_tag="ACF3UF_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFD3671434.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5767..6708
                     /locus_tag="ACF3UF_001293"
     CDS             5767..6708
                     /locus_tag="ACF3UF_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFD3671435.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6777..7508
                     /locus_tag="ACF3UF_001294"
     CDS             6777..7508
                     /locus_tag="ACF3UF_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3671436.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7652..9832
                     /locus_tag="ACF3UF_001295"
     CDS             7652..9832
                     /locus_tag="ACF3UF_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFD3671437.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9852..10334
                     /locus_tag="ACF3UF_001296"
     CDS             9852..10334
                     /locus_tag="ACF3UF_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFD3671438.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10350..11111
                     /locus_tag="ACF3UF_001297"
     CDS             10350..11111
                     /locus_tag="ACF3UF_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFD3671439.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11242..12576
                     /gene="murC"
                     /locus_tag="ACF3UF_001298"
     CDS             11242..12576
                     /gene="murC"
                     /locus_tag="ACF3UF_001298"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFD3671440.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12883..13368
                     /locus_tag="ACF3UF_001299"
     CDS             12883..13368
                     /locus_tag="ACF3UF_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFD3671441.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13361..14044
                     /locus_tag="ACF3UF_001300"
     CDS             13361..14044
                     /locus_tag="ACF3UF_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFD3671442.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14170..16815
                     /gene="polA"
                     /locus_tag="ACF3UF_001301"
     CDS             14170..16815
                     /gene="polA"
                     /locus_tag="ACF3UF_001301"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFD3671443.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16860..17696
                     /gene="mutM"
                     /locus_tag="ACF3UF_001302"
     CDS             16860..17696
                     /gene="mutM"
                     /locus_tag="ACF3UF_001302"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFD3671444.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17660..18289
                     /gene="coaE"
                     /locus_tag="ACF3UF_001303"
     CDS             17660..18289
                     /gene="coaE"
                     /locus_tag="ACF3UF_001303"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFD3671445.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            18341..18673
                     /locus_tag="ACF3UF_001304"
     CDS             18341..18673
                     /locus_tag="ACF3UF_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFD3671446.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18985..19476
                     /gene="nrdR"
                     /locus_tag="ACF3UF_001305"
     CDS             18985..19476
                     /gene="nrdR"
                     /locus_tag="ACF3UF_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFD3671447.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19499..20872
                     /locus_tag="ACF3UF_001306"
     CDS             19499..20872
                     /locus_tag="ACF3UF_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFD3671448.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20872..21798
                     /gene="dnaI"
                     /locus_tag="ACF3UF_001307"
     CDS             20872..21798
                     /gene="dnaI"
                     /locus_tag="ACF3UF_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFD3671449.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21927..22367
                     /locus_tag="ACF3UF_001308"
     CDS             21927..22367
                     /locus_tag="ACF3UF_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFD3671450.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22511..23212
                     /locus_tag="ACF3UF_001309"
     CDS             22511..23212
                     /locus_tag="ACF3UF_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFD3671451.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23209..24330
                     /locus_tag="ACF3UF_001310"
     CDS             23209..24330
                     /locus_tag="ACF3UF_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFD3671452.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24345..25577
                     /gene="pepT"
                     /locus_tag="ACF3UF_001311"
     CDS             24345..25577
                     /gene="pepT"
                     /locus_tag="ACF3UF_001311"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFD3671453.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25709..26617
                     /locus_tag="ACF3UF_001312"
     CDS             25709..26617
                     /locus_tag="ACF3UF_001312"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3671454.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26652..26924
                     /locus_tag="ACF3UF_001313"
     CDS             26652..26924
                     /locus_tag="ACF3UF_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFD3671455.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26935..27981
                     /locus_tag="ACF3UF_001314"
     CDS             26935..27981
                     /locus_tag="ACF3UF_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFD3671456.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            28232..30841
                     /gene="clpB"
                     /locus_tag="ACF3UF_001315"
     CDS             28232..30841
                     /gene="clpB"
                     /locus_tag="ACF3UF_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFD3671457.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
BASE COUNT        10445 a         5331 c         6739 g         8396 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     4801 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
     4861 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
     4921 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
     4981 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
     5041 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
     5101 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
     5161 tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagga ggaaacagat
     5221 gtttacgaat gaaataaaaa tcatgcttta tgtggacgat gtagaaaaaa atgcaacgtt
     5281 ttggagagca gttggctttg cggaaaaaga tcgtcaagaa atggatggga cgcttataat
     5341 tgaagtagga gttgaggaca gtcaaacctc atttctgtta tatgatcgag catttgttga
     5401 gtcccattca cctggcacag ctactagtgc cccatctttg atgttttaca gtaaagatat
     5461 ctttggacta tataaaaaaa tgcagacgca atcagtcaca ttaggtgata tggtacagct
     5521 tggagaagaa tatgtcttta actttgctga tcccgatggc aactactttg cggttacagg
     5581 taaataatag aaataaagac tttgtttttc tgtgcgaaac aggaaagcga agtcttttta
     5641 attcaaataa taatattatg taaacaaaaa actttccatg cgtaattata cacaagcaaa
     5701 taaatcgtca aatgcgaacg ccttctttat actgtttagg aacgaaaaga aggaaggaag
     5761 aaatacatgg attatcaagt actgctttat tacaattata caaaaatcga agaaccagag
     5821 gaatttgcca aaaatcattt agccttttgc aaatctttgg atcttaaagg tcgtattcta
     5881 gtagctgaag aaggaataaa tggtactgtg tctggaaccg ttgaaaacac gactgcctat
     5941 atgaaagcaa tgaaagctga tcctcgattt gctgatacga tgttcaagat cgatccaagc
     6001 gaaggacatg cctttaagaa gatgtttgta agataccgtc cagagcttgt aagtttaaag
     6061 ctagaagagg acattgatcc aaaccaagtg acaggtgcct atctttcacc gcaagaattt
     6121 aaagaagcta ttttagatga acagacagtg gtgattgatg cacggaatga ttatgaatat
     6181 gacttgggac attttcgagg ggctgtacgc ccagatatac gcagttttcg agagcttcca
     6241 gactggatcc gcgagcacaa agaagaattt atggaaaaac gggtagtgac ctactgtact
     6301 ggtggcattc gttgcgagaa gttttctggt tggcttgtcc gtgaaggatt caaagatgtc
     6361 ggacagctgc atggcggtat tgctacttat ggtaaggatc ctgaagtcca aggagaatta
     6421 tgggacggca agatgtatgt gtttgatgaa cggatcgctg tcgatatcaa ccaagtagat
     6481 aaacaaatcg tcggtcgcga ctggtttgac ggaacaccat gtgaacgata tatcaattgt
     6541 agcaatcctg agtgcaatcg tcagattctt gcttccattg aaaatgaaga aaaacattta
     6601 ggagcatgta gcatagagtg tgcgaaacat ccgcgcaatc gctatgttca agaccatgga
     6661 atctctccag aagaagcaga actgcggttt acagctttaa ttaaatagaa aacaatagtt
     6721 ttgattgtcg accatttcca atatgcgcta tactagcgtt gaggatggtg atccacatga
     6781 aatcattgat ttatgctatt ggggatgtcc atggcaaaca tgagcttttt gaaaaactta
     6841 ttcactatta tgatccaaag atccatcagc ttgttttatt aggggatctc aatgatcgag
     6901 gtcctcgtac aaaagaatgt tttttattag gaaagcaatt agtcgaagaa acaggagcca
     6961 tttacctccg gggaaaccat gaagaatatt ttttgcaatt tctgcaatca ccggaggact
     7021 ggtatgcgcc ttatatgaga aatggtggaa aagaaacgtt tgaaagcctg attcacccag
     7081 gggcatcgga ggaatactcc ccaactgaaa tctcgatgat gatccaatcg agatattcag
     7141 aactgattaa atttttagtc cagcgcccct tgtattatga atgggaaaat tatctttttg
     7201 tccatgccgg tgtggatttg acaaagaaag actggcgtaa gacaagtcta agagacttta
     7261 tttggataag ggaaccattt catgaaggga aaaacaatac aggtaagaca attgtatttg
     7321 gacatacgat tacaccaatg ctccatggag atatgcagac aacagacctc tggattcagg
     7381 atcataaaat cggaatggac ggtggggctg tattcggagg gtcattgcat ggggttgttt
     7441 ttgacaagga aggtattctt caagatattg aatatcagaa caacgaagga ccttggcatg
     7501 gaatctgact aatggaaaga atgaaggagc tgtgactttg ttgcggctct ttttattttt
     7561 atagagaata ttgtttcttt cagtagttta acccaggata aaaagtatga tagaataaag
     7621 aagcaatttt tagcagaaaa gaggcatttt aatgacggaa aatttgaacc agacgatcat
     7681 tcagcttgta caaaaagaac tttcagacta tcgtcctaag cagttgacta ctgtacttaa
     7741 tttgttaaat gaaggaaaca ctgttccttt tatcgcgcgt taccgaaaag aaatgactgg
     7801 aagtcttgat gaagtccaga ttcgtgaaat cgaagagcgg tatgcctatc ttgaaaactt
     7861 agaaaaacgt aaaactgaag tgattcggct aatcgatgaa caagggaaac tgactcccga
     7921 gttagaagca gaaatcaccc aagccgtgaa aatgcaacaa gtggaagatt tgtatcgtcc
     7981 atacaaacaa aaacgacgga caaaagcaac gattgctaaa gaaaaaggac ttgaaccact
     8041 cgcgaagtgg ctgatgcagc ttacagatgg agaggtgcaa tctgaagcag aaaaatatat
     8101 tgacaaagaa aaagaagtct cttctgccga agaagcgttg cacggtgctc atgagattat
     8161 tgctgaacaa gtcagcgata atgcaaaatt tcggacttgg attcggtctt atacgtataa
     8221 caaaggtatg tatgtcagca atgtcaagga tgagcaagca gatgaaaaag gcgtatatga
     8281 aatgtattat gactttgcag aacccgtcca taaaatggtt tctcatcgaa tattagctac
     8341 taatcgtgga gaaaaagaag atattctgaa agtattcttt caagtagatg aagcagcaat
     8401 tttagcttac ttggatcgcc aaatagtcaa aaatcctgcc tctccttctt cttcattcgt
     8461 cagagaagcc tatcaggata gttataaacg ctttattcag ccagcaatcg agcgagaact
     8521 gcgcaatgaa ttgactgaaa aggcagatga gcaagcaatc gctattttcg gcgaaaacct
     8581 ccgtaatctt ttgttgcaac cgccactaaa aggtaaagtt gtcctgggat ttgatccggc
     8641 ttatcgtact ggatgtaaac tagcagtcgt agatgcgaca gggaaagttt tagcaatcga
     8701 agttatttat cctcataaac ctgcagcgca agcaaaaaga gaagctgctg gaccagcttt
     8761 tatccaatta attaataaat atcaagtaga tatggtagct atcggaaatg gtacagccag
     8821 tcgggaatct gaactttttg tggctgagca gttgaaatcc gccgaccata aaacctatta
     8881 cgctatcgtc aacgaagcag gcgcttctgt ttactccgct agcgaaattg cacgaaaaga
     8941 atttccgcat ctacaagttg aagaaagaag tgctgtttct attgcccgtc gcctgcaaga
     9001 tcctttagct gaattagtca aaatcgatcc taaagctgtc ggagtaggcc agtaccaaca
     9061 tgacgtttct caaaaacgtt tggctgaaca attggatttt gttgtggaaa cagcggttaa
     9121 ccaagtaggt gtggatgtga atacagcaag cccgcagctc ttgcagcata tatcaggatt
     9181 gaataaaaca actgcccaaa acattgtcat ttatcgtgaa gaaaacggag aattcaccgc
     9241 acgaactcaa ttgaaaaaag tgccacgctt aggaccaaaa gcatatgaac aagcaatcgg
     9301 attcttgcga gtccctggtg ggaaaaacat tttggacaac acaggtatcc atcccgaaag
     9361 ttattctatt gcaaaagaaa tattaacttc agtccaactt tcagaaaaag agcttggtac
     9421 agaagaagca gtagaaaaat tgacacgatt atccgtagag aaactggctg aaagcctatc
     9481 agtcggagaa gaaacgttag ccgatatttt agctgggctg acacaacctg gacgagatat
     9541 gcgtgatgag atgccagcgc ccttattacg tacagatgta ttgagtatgg aagacttgaa
     9601 accagggatg gaattgactg gaacggtccg taatgtcatt gacttcggcg catttgttga
     9661 tatcggtgtg aagcaagacg gacttgtcca tatatcgaaa ctcagcaaaa aattcgtcaa
     9721 gcatcctaca gatgtcgtgt cagtaggaga tatcgtaaca gtttggatag aacaagtcga
     9781 tacgaaaaaa ggcagaatca gtttgacgat gctttcccct tatgaagagt aacaatgagg
     9841 agtaacaaaa attgacacaa gaagaactgc agcagttagt agaagagata tcattaaaaa
     9901 gcttccagct tcctttcaag caccaagcaa tgttcaatcc acgcttacgt acaactggcg
     9961 ggcgctatca tttaaacgat catcatttag attttaatgc gaagctattt gaagagtcag
    10021 acgaagagac gattgcagga atcatcaaac atgaactttg ccattatcat cttcatctag
    10081 ctggaagagg gtatcagcat aaagatatgg atttcaagta tcttttgaaa aaaacaggag
    10141 ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa gatggagtat tatcgatgcc
    10201 aagattgttc tgccacgatc tgccgcaaga gaagaatcga tgtacgcaaa tatcgttgtg
    10261 gaagatgtca tggagaaatc aaatggattg agacaaaaag agaagacttt aatgaagcac
    10321 aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag tgagcagagg aatctaaaag
    10381 actggaatca gctattaaat tttttagccg cacctgaaga gggaaatttt gaggaactga
    10441 cggcacctac acttatttta gctggaaact gtcttcctat cttagctgat aaagcagcac
    10501 aaatgtattt aaatggccaa gtagatcaat tgtttttggt cggaggggtg gggcatgcga
    10561 ctagaatcct ttatgagaat tttgaaaagc aaggatttca ttttgaagat ggcatgagtg
    10621 aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga tttgcccgat aaggcttttc
    10681 tgatagaatc gaagtctaca aattctggag agaacgccac tttttcactg gagattcttc
    10741 attccttagg agctgtacca gaaaaaatct tattgatgaa tgatccgaca ctgcaacgca
    10801 ggactcgagc aacttttgag aaagtatggc aaaatgaaca aactattttc gcgaatgctg
    10861 tgccatttgt gccggaaatc cttcactttt ctgaagagat catctttaca gcaaaagaac
    10921 tgaatcatca atggcctaag gaatatttcc atgcgctagt attaggagaa atggaacgtc
    10981 tccatgacga tgagaacggc tatggtccga aaggaaaaga ttttattcct cacattgata
    11041 tatcagagga agtttggtct tcttacacca gaattaaaga gtcaataaaa acggattttt
    11101 ctcgtacttg accattttag caagcgaatc ctcctttcca aataaatttg gttgaaattt
    11161 tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa tagctaaaag aatggacgct
    11221 agataagaga agaggattca aatggaaaat caaaataaat tgtatcattt tgttggtatc
    11281 aaaggttcag gaatgagctc cttggctctt gttttacatg aacaaggtct aaatgtccaa
    11341 ggatcagaca ttgaaaaata tttctttaca caaagagatt tagaaaaagc aaatatcacg
    11401 attctgccat ttaacgcaga taatgtaaaa ccagggatga cgatcattgc aggaaatgca
    11461 tttcctgatt cacatgaaga aatccagcga gcaaaagaat taggtttgga agtgattcgc
    11521 tatcacgact ttattggtca ttttatccaa aattatacga gtatcgctgt aacaggctct
    11581 cacggaaaaa caagtacgac tggactgctc tctcatgtat tgagtggtgt ccgtccaaca
    11641 agttatctaa ttggagatgg aacaggacat ggtgatccgc aagcggaatt cttttcattt
    11701 gaggcctgtg aatatcgccg tcatttcctt gcctattcac cagactatgc aatcatgacc
    11761 aatatcgatt ttgatcatcc ggattattat acaagtatcg acgatgtatt tacagctttc
    11821 caaacaatgg ctggacaagt gaaaaaagct atttttgcgt atggtgacga tgcttattta
    11881 cgcaaattaa aagcaaatgt gccgatttat tattatggtg tcacagaaaa cgatgatatc
    11941 caagcacgaa acatcgaacg cacaacttct ggttctgctt ttgatgtcta tcatggggat
    12001 gaatttgttg ggcacttcac tgtaccagca ttcggtaaac acaatatctt aaatgcttta
    12061 ggtgttattg cagtagctta tttcgaaaaa ctggatctga aagaagttgc agaagaaatg
    12121 ctgactttcc caggagtaaa acgtcgattc agtgaaaaga tcgtagcaga catgaccgta
    12181 gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa cgattgatgg cgcacgccaa
    12241 aaatatccag ataaagaaat aattgcagtt ttccaacccc atacgtttac gcgtacgatt
    12301 gcattgatgg atgaatttgc agaagcactt gatttagctg ataaagttta cttatgcgat
    12361 atttttggtt cggctcggga agaacaagga aacgttaaga ttgaagacct tggagcgaaa
    12421 atcaaaaaag gtggagaagt catcaaagaa aataatgtat ctccattgtt agattatcat
    12481 gatgcagtag taatcttcat gggtgctgga gatgttcaaa aatttgaaca agcgtatgaa
    12541 aaacttttaa gcagcacgac gaaaaatgta ctgtaataca attactgcag tgtccttata
    12601 aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc cccttttttg caacttatga
    12661 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aatcaaatca aaaacatgag
    12721 aagctgtttt ttcttggctg ttcttattat ttgatgcagg acagcttttt cacgacctct
    12781 gtaaactata ggaatctgtt aaatcaaggg agcagaactt gccttttacg ctacttttgg
    12841 tacaataatg tatgattaaa aataaactgg agggtttcta tcttgaacat aggtaagccg
    12901 agaaaactag gaaaaacaat aaatgaaatc gaggaaggcg actcgttatc cttaacagaa
    12961 tctattgaag ataaccagct tttgctgtat ttgggattga cgaatgatgc aaatcctttg
    13021 tatatccaac atgactttgc acaaaaaaca gaatatcaac agccaatcgt tccatcagtg
    13081 atgctgatgg ggatcatcac aagtgcaatt tcaaagcatc ttcctggacc aggatcacat
    13141 gttgtcaatt tttctgtcaa ttttattgaa ccggttttcc attatgaaac actgactttt
    13201 cagtttgagg tcataaaagt agataagatg aaggatgtgg tgacgatttc tgtagaagcg
    13261 gagaatacga acgaagatcg tgtgttggat gctgtcgtta tggtccaacc gccacaagtt
    13321 cctgaattgg aaatagcaat cgaaagtgaa ggtgaattga atgaataatc caagtacatc
    13381 aatgtcaggt atcaatcgtt tttatgcaaa agtttatgga tttttaggta tgggacttgc
    13441 ccttagtgca gtcacttctt acttggctct ttgggtattt cctttgcaat tagcaacttt
    13501 tatcaataat tttccactag gctttgtggg tctgtggatc gttgaactga ttttagtaat
    13561 ggttctaggc gtaaaagcac aaaagaatcc gagcttagca atcggtggat ttattgccta
    13621 ctctcttttg aatggcataa cattagcggt tactcttgca tactacgata ttggaacagt
    13681 aacgcaagct ttcttgacag ctactttgat gttcatgggg atgtctgttg tcggagtaac
    13741 aacaaaaaga gatcttagcg gggttggaag agcaggacag gcagctttaa tcggagtgat
    13801 cattgcacta gtcttgaaca tcttcatttt gagaagtagc gtagttgagc tgttcatctc
    13861 cctactgtta gtcgtcatct ttgcagggat tacagcttat gataaccaaa gcatccgtaa
    13921 tatctatgtc cagacaaacg gaacagcaca tagtggaatt gctgtattca tggcattgaa
    13981 gctgtatttg gactttatca acttgttctt ggcgtttctg agaatctttg gacggaacaa
    14041 ctaaaaaaaa aaaaaattca tcagttgggg ctataccgaa ttatttggta tggtcccgct
    14101 ttttcttttc gcattccgca ggattctttg ttagaatgaa taagaacttt acagtaagga
    14161 gttaagaaga tgacaaaaaa taaattatta ctcgttgatg ggaacagtgt ggcttttcgc
    14221 gcattctttg cgcttcacaa ttctcttgaa cgtttcaaaa atagaaacgg tcttcataca
    14281 aatgcaatct atgcattcaa tacgatgttt gaaaatgtta tgcaaaaaga gcaaccgact
    14341 catgttctgg ttgcgttcga tgcaggaaaa acgacttttc ggacagaaat gtatgcggag
    14401 tacaaaggtg gaagatccaa aacacctggc gaattcaaag aacaaatgcc atatatacgt
    14461 gatttgttga caggactagg ggtacagtat tacgaattgc ccaattatga agcagatgat
    14521 attatcggta ctttggcaga aaaagtagac aaagatcaat ttgatgtcgt cgtgctttca
    14581 ggtgatcggg atttgactca attagctagt aaagaagtaa aagtggatat cactgtaaaa
    14641 ggtgtcagcg atatcgaaag ctatacacca gaacatgtag cggaaaaata tgatgggttg
    14701 acgccaaaac agattattga catgaaggga ctagccggag atgcctctga caatatcccc
    14761 ggtgtgacta aaatcggtga aaaaacagct atcaagctat tgaaacaata tggctcagtc
    14821 gaaggaattt atgaacatat cgatgaaatg aagcaaagca aaatgaaaga aaatctgata
    14881 aatgacaaag agcaggcttt cttatcgaaa aaattggcga ccatcaatac ttcagcgcct
    14941 gtggatgtct ctatcgactc attgaagtat gaagggaaaa atctcgataa actcgttccg
    15001 ttttataaag aaatggattt caatcagttc ctttctaaat tgaatatcgt agaagaagaa
    15061 gtaaaaatgg atgatatttt gtttgaagtc gttcatgaat tcaaagagga aatgtttact
    15121 acggatatgg cgttgtacgt ggaaatgatg ggcgacaatt atcatacaga ggaaatcgtc
    15181 ggagtagcgt gggggacaga aaagaaaatt tatgtcacga acgatctatc tgtattcgaa
    15241 aaccgagcgt tccattcttg gatcactgat ccgactcggc tgaaaaaagt atatgatgcg
    15301 aaacgaactt atgttgcttt aaaccgctat actggaaaaa cgaaaggaat cgattttgat
    15361 gtcttgctag gtgcatacct tctcgatacg aatgaaaaaa gcacagatat cgaaggaata
    15421 gctgctcatt acggatacaa cgatatccaa tcagatgaag ctgtatacgg caaaggggcg
    15481 aaaaaaggtt taccagaaga agaggaactc ttttttgctc atttagcgcg aaaagtagct
    15541 gcaatcaatg cgttgacacc aaaattgagc caagaactgg cagaaaaaaa ccaagaagat
    15601 cttttccgga aaatggaact gccattgtct atcattttgg cagagatgga aataagcggg
    15661 atcaaagtag atgcgactcg cttacaagaa atgaagggcg agttctctgc tcgcttaaga
    15721 gagatcgaac aaaaaatcta cgaagaagcc ggcgaagaat tcaatttgaa ttcaccaaag
    15781 caattaggag tgatcttatt tgaaaaaatg ggattacccg ttatcaaaaa aacaaaaact
    15841 ggatattcca cagccgtaga tgtactggaa cagcttcgtg aacaagcacc aatcgtagag
    15901 gatatcctca cctatcgtca aattgcaaaa attcaatcta cctatgtcga gggactgctg
    15961 aaagtgatcc aatcagatgg aaaagtgcat acccgttatg tccagacatt gacccaaaca
    16021 ggacgattaa gctctgttga tcctaatttg cagaacatcc cgattcgatt agatgaaggg
    16081 agaaagatac gtcaggcatt tgttcctaga gaaaaagact ggctgattta ttcttctgac
    16141 tattcacaaa tcgagttacg cgtacttgcg catatctcaa atgatgaaca tttgaaagct
    16201 gccttcctag aaggtcaaga tatccatgcc agcacagcga tgcgtgtatt tggaatcgaa
    16261 aaggcagagg atgtcacacc aaatatgcgt aggcaggcaa aagcagtgaa ttttggtatc
    16321 gtgtatggca tctctgatta cggactttca caaaatctag gaatcagccg aaaagcagca
    16381 cagcaataca tcgatacgta ctttgaaaaa tacccaggtg tcaaagaata tatggaaaga
    16441 atcgtacgcg aagcaaaaga ccaaggctac gtcgaaacgc tgtatcaccg ccgtcgatat
    16501 ctgccagaca tcaattcaag aaattacaat atccgttctt ttgcggaacg aacagctatc
    16561 aatacaccaa tccaaggaag tgctgctgat attttgaaaa tcgcgatgat cgaattggat
    16621 aaacgattaa aagaaacagg tcttcaagct acgatgctgt tacaagttca tgatgaactt
    16681 gtcttcgagg taccggaaaa agaacttgaa tcattagata aattggtgaa ggaagttatg
    16741 gaacaagctg tttctcttca tgtaccactg atcactgaca gcagttgggg aaaaacgtgg
    16801 tacgaagcaa aataaacatt gtttaagaca gagcaatata atgaaggtga aaagaaaaaa
    16861 tgccagaatt accagaagta gaaaccgttc gtaaaggatt ggaacggtta gtagtaggaa
    16921 aaacgattca aaaagttcag gtcttgtggc ccaagatcat cgagcaacca gagacaccca
    16981 tctttgaggc ttctcttgtt ggcgaaacca tccaatccat tggacgtaga gggaagtttt
    17041 taatttttca tctcgatcat tgtgaactga tctcacactt gcgaatggaa ggaaaatatc
    17101 aatttacgaa agaaaataca ccaatcgata aacatacgca tgtacttttc ttttttgagg
    17161 atggaagcca acttcgctac aacgatgtac gaaaatttgg tcgtatgaca atcgtcgaaa
    17221 aaggagcaag tgcaacttac cgaggaatca tgaaattggg acctgagcct ttgccagata
    17281 gcttcttatt agcagatttc gcaaatggac tgaaaaagtc ccacaaagca atcaagccat
    17341 tgctgctaga ccaacgtcta gtgactggtc taggtaatat ttatgtagat gaagcattat
    17401 gggaagcgaa gatccatcca gaacaaccgg cgaacacact gcgccccaaa gaggtagaac
    17461 aattacgtct atcgatcatt gatgttttgg atcgtgcaat agaagccgga ggtaccacga
    17521 ttcgcagtta tttgaatgca ttaggagaat caggcggatt tcaagtagca ctgcatgtct
    17581 atcagcaaac tggcaaacca tgtatacgtt gtggaacgcc gatcgtgaaa acaaaagtgg
    17641 cacaaagggg gacgcactat tgtccgaatt gtcaaaggct aaaaatcgca aagtaggatt
    17701 tgttttaggt ttgacgggtg gaatagctac cggtaaaagt acggcagcca aagtctttca
    17761 gtctcatgga tttcctttga tcgatggcga tgtgattgcc agagaaactg ttgagcctgg
    17821 aacgcttgct ctgaggaaaa ttgtatcagt gtttggccaa gaggtattgc agcctgatgg
    17881 gcaactagat cgagggaaac ttgggatgat tgtttttcca tcaaaggaaa aacggcaaaa
    17941 acttgatcag ctattagatc cgtttatccg aaaagcgata aaagatcaaa tcgcctctct
    18001 aagttccaat catcctttag taattgtaga tatcccattg ctctacgaag gtcattatga
    18061 ccactatatg gatgcagtag ctgtcgttta tactacgcca gaaactcagc ttcagcgttt
    18121 gatgaaacgt aatcaactga cgctagaaca agcgcagcag agaattagta gtcaacttcc
    18181 aatcgaagaa aaaaagcagc gtgcggatat tttgttcgac aacaatggaa caaaagaaat
    18241 acttgtggga caaatcgaaa attggctttt tgctaatcgc tttctttgag tatctgtgtc
    18301 aattttgcta tcctgagtat atagaaagtg agggatagcg atgggatcat taaaaaatca
    18361 aaaggataaa gtcgtaggta acgcaaaaga aaaaatcggc gagatgctca ataaagaaaa
    18421 tctaatcgat gaaggtcgta cgcaatcaga aacagcagaa gaaaaagaaa agcagtacca
    18481 agcaagaatc gatgaaatag aagaccagca ggcagaagaa gaagcgaagc ggcaagattt
    18541 gactcaagaa cgaaaaaatc cgacacctga tcgtagtaaa acaccgctcc cagaaagtga
    18601 ccacattccc gatgagcaaa aaatcgagga acagcgaatg aaacactata caggaatcga
    18661 agagaagtta taaaatagta aaaaatcgag atgtgacttg aagcagatga gaaggtgttc
    18721 atctgcttca agttttttgt gctagatgac taaatcagct tttgtgtaag ttatttctca
    18781 gtaatcaagg tgatcagtat tggaaaattg aaatttagta aggacagggg acacaattac
    18841 gcatgaaagt agaaaaaatt gttcttatat ccgtgttttt tgggtaggac agtcgcgttt
    18901 gtgatttgtt tcgtgttata atacaactag ttgtaaagaa agacacatcc tttatataaa
    18961 atgcgatgca agaggtgaga caaaatgaga tgtcccagat gtcaacataa taattcacga
    19021 gtaatcgaca gccgtcaagc agatgatgga cgtgcgatcc gtcgccgtcg cgaatgtgag
    19081 aattgttcgt tccgattcac tacatttgaa cgaattgaag ctgctccgtt attagtaatc
    19141 aagaaaaacg gggaacgcga agagttcaat cgcgataaaa ttttaagagg actcatccgt
    19201 tcagcagaaa aaagacctgt agctatggaa caaatggaac aaatcgtcaa ccatgtcgaa
    19261 aaccgcgtac gcagtctcgg agaaaacgaa gtatcgacga atctaattgg tgaatatgtg
    19321 atggaagatt tagttgattt agacgaaatc gcttatattc gttttgcaag tgtttatcgc
    19381 cagttcaaag atatgtctgt tttcttaaaa gagttgcaag atatcgtgga taaagcaaaa
    19441 gaaaataata aagagaataa taaagaaaac aattaagaaa caaaaaggag gcatttcctt
    19501 ggaaaatgct tggaaagagc ttcaaccaaa aaatatttac caaggaagaa aagcggctcc
    19561 gctgagagaa gacagcaaga acgccttgct gtatctttat cagccactaa tcggcggaga
    19621 agccttgagt atctatttca ccctgttatc agaaatctct caagaatctg gcaaaggtcc
    19681 tgaagggatg catgcagatc tgcttagtag tctaggctgc ggtatcccgc aattttatga
    19741 tgcaagaaaa aagctagaag gaatcggctt actggatgtt tattttaaag aagatagtga
    19801 tctgggacct cgttttattt atgagctgtt agaaccactc attcctaaag catttttcaa
    19861 agactctgtt ctggcttttc ttcttctgga aaaagttggt gaacgacgat tccagaagct
    19921 tacccaattc tttgaaccta aaaggcatac agcagaggga tatcaaaaaa tcacaaaaaa
    19981 atttttagat gtttatcgct tcaatgaagc agtgtacgct gctaatcaag aaaacatcga
    20041 atcgctgaat aaatcttttg aagaatctga atcagtagca ttacttgaag cagattcgac
    20101 attcgattgg cagtttttga atgattggct ggcaaaaaaa catattgcaa gtcttgatga
    20161 tccaatcatc aaacaagtcg acatgtatca tcagctttac ggtttcgatg aattgacact
    20221 tggcgaactg atcagtcaat cttatgactt tagtgaacaa aaagtatctg aaaaagaact
    20281 gcaaaaagcc attttggcaa tgcagagacg tccggtgaag caaacaaaag aaacagttgc
    20341 ggtttctgaa aacagtaatg aaccctcgtc aaacgaacat ttgacaaacg cagcgcttca
    20401 gctgataaaa gaagcacaga gcattccacc gatgaaatat ctggaagcaa tcaagtcaga
    20461 aaaaggcgga tatgtttcta aacaagaaaa ctggttactg caagatcttg tttctcaatc
    20521 aggtctttcc agtagcgtga tcaatgtttt gctgaattat gtactagtga tcaagaataa
    20581 tgctagctta aatgccagtt atgtaaatac agtggcaaat gaatgggcac aaaagaaaat
    20641 cgccacagca gaagaagcga tccagcacat tcggcaaata agtaatcaag caaaacaatc
    20701 aaaacaaaag aagcaaacaa attatcaaac tggcaagcga aatgttcgac gggaaaagct
    20761 tcctgattgg gtcaaccagc caaaagatga aaaacagatc agcagcgaga aaaaagcaga
    20821 gattgaccgc cgttttaaag aatacctggc aaaaaaggag ggtgatatct agtggaagac
    20881 gtaggcaaag aattgaagag gatcatcagc aaacgcaatt atcaagaaaa gtatgctgaa
    20941 atgatcgctg aagtcttaaa tgatgcggat gttcaagctt ttctaagcgc acaccaagaa
    21001 gaattgacac aagcggatat tgaaaaaagt tacgctaaat tgtatgaatt cgtgcaagaa
    21061 aagcgtaaat atcaaaaaaa cgatccaacg atgatcgctc ccggctatga gccgaagctg
    21121 acgttgaatt ttcattatgt ggatgtcact tatgtaccaa cggaagcatt gttagcacgg
    21181 caaagacaag aagaaatcag aagccgagta aaagcaatgg atatgccaaa agatattcaa
    21241 tcggcttctt ttgaaaactt tgaacgtaca gatggacgag gatatgcgag cttagaagcc
    21301 ctagattttg tagagaaata tactgctgat ccaaaagggt atcataaagg actgtatcta
    21361 gtaggaagtt ttggtattgg aaaaacatat ttattaggag caacagcgag agaattagcg
    21421 attgctggat tcaccacgac gctagtccat tttccgacat ttgccgttga gatgaaacag
    21481 gcaatcggaa aagatcaagt ggcagaaaag ttagatgcag tgaaacgttc acctattttg
    21541 atgatcgatg acattggtgc agatgcgatg agtagttgga tacgagacga agtattcggt
    21601 gttatccttc aatatcggat gcaggaacag ttaccaacct tcttctcatc gaattttaca
    21661 atggatgaat tggaacagca tttgtccgtc actcaacgtg gagatgaaga gccgctaaaa
    21721 gcgaaacgga taatggaacg catacgttat ttgacaaaag aaatcgaaat gactggtcgc
    21781 aaccgacgca atggttgaac agttgacaag tccaactgac atttgaccta gtagtaaaag
    21841 caggtcagcg aatcattata tggacagaaa tgaccggaga caatcaccgc aacaagtaat
    21901 gcagaaactt aaacggagga ttttttatga gggctatttt ttctagtata tctgtagttg
    21961 gtctattttt tcttttagca ggctgcggta gcgcagatag caacacaggt tctgttgatt
    22021 cgattgatgc gggtcaaaca gtaaaaacaa gcagtacgaa aacggagaga caaagcatat
    22081 ttgtcggaac gattgaaagt atcactcaag tagaagcaga agaagaaacg cttcagttga
    22141 aactcgtcga tgtcatggcc aaagaagatc cagcgaatat gggaacgtca ttcagcaatg
    22201 acggagtgat cttaaatgct actgctgaaa aaataagcgt ggacataaat gaattgaaaa
    22261 tcggtgacaa agtccaattt acattagttg agatgccgat catgacgatg tctatcccac
    22321 cgcaagttcc tggagattcg attattgatg tttcattgaa caaataacca ataacatttt
    22381 ttcaaaaata agaaaatgtt gttttataga acgaaaaggt atatttttta aggagatatg
    22441 ggaatttttt tattcctagt ctccttattt tatttggaaa atgctataat tatctagaag
    22501 gagtgaagct atgaaccatt tagatttatc tcagcgctta gccgcagtgg gtgactttgt
    22561 ccctgaatcc gctcgtttag cagacattgg atcagatcac gcttacttac ccgttgcatt
    22621 gatattaaga ggaaaaatcg aatatgcagt tgctggtgaa gtcgttcaag gtccttatga
    22681 atcagcacgt aagcaagtca aaaaagatgg attagaagac cgtatcaccg tacgccttgc
    22741 aaatggtcta gatgctatcc agccacaaga tggtattaca gctgtcacga ttgcgggtat
    22801 gggaggttca ctgatccgag atatcctaga agctggcaag ttgaatcaac gcttaagcgg
    22861 acaagaacgt ttgatccttc agccaaacat cggagagcgt acattacgat cttggctgca
    22921 agaaaatcag tataaaatcc aatcagaaaa aatacttgaa gaaaataaaa aaatatatga
    22981 aatcattgta gccgaaaaag aacaaaaacc agttacttac aatgaaatgg agctgatgtt
    23041 cgggccattt ctgcttgaag agaaaagtga gatcttcaaa tcaaaatgga caagagagct
    23101 tcaacaaaga aaagctatcc gtgaacagct caaacaagca gctaatcaag aggcacgtca
    23161 aaaacaaatc gagcaggaaa tccaaatgat tgaggaggtt ttaaagccat gacaatcagc
    23221 ggacgcactt tcatccaaaa gtttgaaagc tattgtcctc agtggctagc tgaagaagga
    23281 gacccagtcg gactgcatat cggaacattg gataagccaa tccaacgagt aatgatgaca
    23341 ttagacgttc gtccagaagt ggtcgaagaa gcaatcaaga aaaaaatcga tttgctgatt
    23401 gctaaacatc ctccaatctt tcgtcctgta aaacggctgg ttactgatca gccacaagaa
    23461 aaaatgtatg cagatttgtt gaaacatgat attgccgtct atgcagcaca cacgaacatg
    23521 gatattattt gggatggact gaatgactgg ttttgtgaac ttctcggtat tgaagtggag
    23581 agttatttag taaagactca tgagattcat tataaaaaac tggccgttta tgtacctgtg
    23641 gatcatgcac agaaaatgcg tgaagtatta gctgcagctg gtgctggtac acaaggtgat
    23701 tataccggta caagttttac ctcgattgga cacggtcgat ttactccgga agctggtgca
    23761 caaccagcga ttgggaaagt agggaagaca gaacaagttc aagaggcaaa agttgaggtt
    23821 attttgccgg aaactatcga aaaacaagtg attcaagcca tgcggtcagc tcatccttat
    23881 gaggaacctg cttatgatct tttcgctata gatgaaccag tcgaaatgtt tgggttagga
    23941 cgagtaggtg aattgccgca agaaatttct atagaggcat ttgtagaaca agtaaaagaa
    24001 gcgttccaac tagatggact gagaatagtc cagccaaaaa atgcaaaatc ctctgtgaag
    24061 cgcattgcga tttgcggtgg aagcggtgaa aaattttatc cgcaagcaat cgcccaaaga
    24121 gcagatgtct atatcacggg agatatctat tatcatacgg ctcatgatat gcaaagcgct
    24181 gggttgattg caattgatcc cggtcattat attgaatcgt tatgcaagca acgatttatc
    24241 gagaaatttg aatcttggaa acaagaagaa aattgggata ttaacttttt cgtttctgaa
    24301 acaaatacaa acccatttca atttaattaa aaggagagaa tactatgtac gaaaatcttt
    24361 tgccacgttt tttacgatat gtcaaaacag aaacacgctc cgatgcaaca agcaaaacga
    24421 ctccatcgac tcagacacaa gttgcttttg cgcaagaatt gaaaaaagaa ttagaagagt
    24481 taggcttagc tgatgttttc tataatgaag ataacggatt cgttatggga acattaccaa
    24541 gcaatgttga tcatgaagtg cgttccattg gatttatttc ccacatggat acagcagatt
    24601 ttaatgcagt aggagtcaat ccacaaatca ttgaaaacta tgatggcgag tctacgatcg
    24661 tactagatgc ggaagaacgc tatacattga atacaaaaga ttttccaaat ttgaaaaatt
    24721 atgaaggcca cacattgatc acaacagatg gcagtacatt actgggagca gatgacaaat
    24781 cagggattgc ggaaatcatg actgcaatgg agatcttgat caataatcct tctatccctc
    24841 acggtaccat caaagtggct tttggtcctg atgaagaaat cggtgtcgga gcggataaat
    24901 tcgatgttga gcaattcgat gtagattttg cttatacagt cgatggtggt cctttaggtg
    24961 agttgcagta tgaaacgttt agtgctgctc aagcaaatat tacgatccaa gggaaaaatg
    25021 tacatccagg gacggcaaaa gatacaatga tcaatgctct acagttagca atcgattttc
    25081 ataatcagct tccagccgat gaagttccag aaaaaacgga aggatacgaa ggtttcttcc
    25141 atttgatggc attggatggg aatcctgaag aagcttctat gagttatatc attcgcgatc
    25201 atgatcgtga aaaattcgaa gcacgcaaag cacaaatcac acatatccaa gaagagttga
    25261 atcagcgatt tgatcaagaa cgaatcaaag tagatatgta tgatcaatat tacaacatga
    25321 aagaaatcat tgaaaaagat atgagcatcg tggaattagc gaaacaagca atgatcgagc
    25381 ttggtatctc tccagtgatc gaaccagttc gtggaggaac agatggttca aaaatctctt
    25441 acatgggtat tccgacgcca aatctatttg ccggaggaga aaatatgcac ggacgattcg
    25501 aatttgtttc tttacaagta atggaaaaag caacagacgt gattgtaaaa attgcagaat
    25561 tgaacacaaa gagttaaaat cgaaaaagaa cagcttatga caaggcgttc gtcccaatga
    25621 tggaatgtca tctgtctaag gctaaagggc aggacaatgg aattggttgt cccgccctct
    25681 tttttgaaga gtaaatagga ggtaaagaat ggaaaagctg ctagtttttt ataacaaaag
    25741 ttcagggaaa gatgagggtg agaaattagc acgctggttt caagattatg taaaagaaaa
    25801 gcagccagaa ttatatgtag aactagctga aactggccca tcgattgatg atgcggaatt
    25861 agtcaagaaa gcagaagcca tagaagctga tactttagta attataggtg gagacggcac
    25921 gattcatcat atcgtccaag cgttccaaaa aacattatct caataccatg tcggattact
    25981 tccaggtgga actgtcaaca accttgcacg tgttcttgag attcccctca aaaaagaaga
    26041 agctgctgac gtgatcctgg aaggcaatgt acggaaaata gactatggtc aagtcaatga
    26101 tgaagtcatt atctctacac tgacaatcgg aatcttagca gatacagcag tttggatcag
    26161 tcaagaagaa aaacagcgtt acggctcgtg gatctttatc aagaagtttt ttaagttatt
    26221 gctgaagaag aaaaaatatc atttggattt agaaacagac gaggagcatt ggaaaggaaa
    26281 atcccaactg ttgacagtca cgatgtctaa ctccgtgggc ggttttacaa attttgacga
    26341 ctcagcgacc ctagatgatg gaaaatttca tgtaacgatc gtaccttcct tagatatttt
    26401 ccgatttatt ttttatttgc ctagaatcat gagaggcaaa ttctatacga tccccggcat
    26461 tacttatttc acagccaaac gcatgaaaat ccaagcgcag gaaaaatctg tgggcactcg
    26521 aacggatgga gacacgacag atgatcttcc agttgaatta tctgttgtat caaaaggatt
    26581 aacagtttat tcaccaaaga aagaagaaaa agcttagaaa tagtagttaa cagaaagttg
    26641 gaagaagagt aatggatgta ttgttacaca atcctttgtg gttttacctt ttcattgtga
    26701 atttttactt attttgtctg atggggtatg ataaacatca ggctagaact agcggctggc
    26761 gtgttcctga gaataatttg atatttgtca gcctgttagg cggtggtttg ggaggattga
    26821 tctctcgaaa agttttccat cataaaactc ggaaaaagaa gtttactata ggattcgctg
    26881 caggtgtact tgttgatttg attctcattt attttttcca ttaaggagca ggagatgtcg
    26941 tctaaaggaa cgaaaactaa aatcattctg aatctgcttt tgctgattgt gatttttgcc
    27001 attatttatt atttaatcaa tcaatcattt gcagatatct ttgccgaatt gctgtctacc
    27061 agtgttgttg ttttggcagc ggctgttata ttagggacag tttaccaaat cgctgaaggg
    27121 cgctcaatca aagaaattgc tgaacctttc gcgccgaatt ttacaacgaa agatgggttc
    27181 ttgacctcta gctatattgc gttttaccga atcgtttcgt ttggtacagg aacgctgatc
    27241 tcggagattt atttttataa caaaaaagga atgaagctat cccagggagc aggggtgaca
    27301 gcactccata tgattatgta caaactggca gtgatcactt atgcattagc tggcttggtc
    27361 atccaattct ctctttttta ttctaatggt ccatcaatga tctggtttat catcgctggt
    27421 atccttttga cgatcgtgat tgttgccttt ttattggcga tgtccgtcag cttgaatgtt
    27481 caaatatttt ttgtcagctt atcgaataag ttatttaaaa gtgagcgttt gcggaaatgg
    27541 gtggatacat gcaatcagca gatctactct ttaagggaaa cggtccaaac cattatccaa
    27601 gacaggactg cgctattgcg gatttatcta tggaatatgt taaaacttgt attttggtat
    27661 gtacttcctt atttgattct gattgaaaac catcctaaaa tagattttct actgaccatt
    27721 tcgtttatca gctttgcagt agtgctttca ggggttattc ctacgcctgc tggtattggt
    27781 tcctttgaat ttgtctattt gttattattc agaccagttg ttggaacagt tgacgcagtt
    27841 tcttcgcttt tactgtatcg tttcagttcc tttatcttgc catttctcta tggatttgtg
    27901 tatgtgattg ctgaacggcg aagagtgatc aaagaagaaa taatagaagt aaaaaaagag
    27961 aataaagaaa atcaagggta ggtcttttat aagatctacc ctttttatca aatcaaagaa
    28021 aaacgttatg gataagataa ttttacgttt gtttggctct ttttttatat acatacaatc
    28081 aattttgttt ttttaagatt tatataagtc gagaaaaaaa gtcaaaaaac tatgtgtata
    28141 ttttgaccaa aattgaccaa agcgatataa tagtttttgt aaagatcaaa gaaataagtg
    28201 atcttacctt taattaggag ggtatacctg tatgaatatt gagaaaatga ctacgacgct
    28261 tcaagaagcg attgctgaag ctcaacagat tgcggtcact cgaaaacatc aagatatcga
    28321 cattgcccat gtatggaaaa tctttttaca atctaatcat tttggtcgaa atttctatac
    28381 ggatgccgga ttggatgtcg aatcttttga acatgaaatt gatcgtctac tggatgagta
    28441 tccagttgtt tctggtggaa acgtccaata tggacaaaac ctcagccaga atttctttcg
    28501 attattgaat gaagcagacc aaatacgtga aagcttcggc gacgagtttc tttcaacgga
    28561 agtcgttatt ttagcgttga tgaaattaaa aaattatccg ttaactgttt atttgaataa
    28621 aaacggatta tctgaaaaag aattgcgtaa aaacatcgaa gagatgagag gaggagaaag
    28681 agtgacctca caaaaccaag aagaacaata caaagcatta gaaaaatacg gcgttgattt
    28741 agtacagcaa gtcaaaagcg gaaaaatgga tccaatcatc ggtcgtgatg aagaaatccg
    28801 tgatgtcatc cgtattcttt cacgaaaaac aaaaaataat cctgttctga taggagaacc
    28861 cggtgtaggg aaaacggcaa tcgttgaagg gcttgctcaa cgtatcgtac gcaaagatgt
    28921 gcctgaaaat ttaaaagata aaacgatttt ttcattagat atgggtgcat tgatcgctgg
    28981 agcaaaattc cgtggtgaat ttgaagaaag actaaaagca gtcttgaaag aagtcaaaaa
    29041 aagtgatgga cgtatcctct tgttcatcga tgaaatccac aatatcgtag gggcaggaaa
    29101 aacagaagga agtatggatg ccggaaatct gttgaaacca atgcttgctc gcggtgaatt
    29161 acatttgatc ggtgccacaa ctttagatga gtaccgtcaa tatatggaaa aagacaaagc
    29221 gttggaacgt cgctttcaaa aggtattagt caaagaacca acagtggaag atacgatcag
    29281 tattctgcgt ggattaaaag aacgttttga gatccaccat ggtgttaaca tccatgacaa
    29341 cgcattagta gcagcagcta ctttatctga ccgttatatt actgatcggt tcttaccgga
    29401 caaagcaatc gatttgatcg atgaagccag tgcaacgatt cgggtagaaa tgaactctat
    29461 gccaacggaa ttagatcaag ttactagacg tttgatgcag ttggaaatcg aagaagctgc
    29521 actgaaaaaa gaatcagatg atgcaagtaa aaaacgcttg aaaaatttgc aagaagaatt
    29581 agctgaactt cgtgaagaag caaatgcgat gaagatgcag tgggaaacag aaaaagaaga
    29641 agtcaattct gtttcagcaa aacgtgctga aatcgataaa gcaaaacacg aattagaaga
    29701 tgcagaaaat aactatgatt tagaacgcgc tgctgtattg cgtcatggta cgatacctca
    29761 attagaaaaa gaattgaagg aattagaagc taaagcaaaa gacagcgaga ttaagatggt
    29821 tcaagagtcc gttaccgaaa atgagattgc tcaagtcgtt ggcagattaa cgggtatccc
    29881 cgtaacgaaa cttgtagaag gtgaacgaga aaaactaatt aaattgaatg aaacacttca
    29941 taaacgagtg attggtcaag atgaagcagt tgatgcggtc agtgacgcgg taattcgttc
    30001 acgggctgga ttgcaagacc caaatcgtcc tctaggttct ttccttttcc taggaccaac
    30061 tggtgtcgga aaaaccgaat tagcgaaagc gttagctgag aacttgtttg actcagaaga
    30121 tcatatggta cggatcgata tgagtgaata tatggaaaaa catgctgtgt ctcgtctagt
    30181 cggagctcct ccaggctatg taggttacga agaaggtggt caattaacgg aagctgtcag
    30241 acgaaatcct tatacaatcg tcttgttgga tgaaatcgaa aaagcgcatc ccgatgtctt
    30301 caatatcttg ttacaagtcc tagatgacgg acgcttgact gattcaaaag ggcgagtagt
    30361 agatttcaaa aatacggttc tgatcatgac cagcaatatc ggttcacagt tactgctgga
    30421 aggcgtgact gctgatggaa cgattccaga agcagtggct gaacaagtca acacgctatt
    30481 acgtggaaac ttcaaaccag aattcttgaa ccgaatcgac gacacgattt tatttacacc
    30541 attgagccta gacaacgtga aaggaatcgt tgacaaaatg gtggcgcaat tggcacaacg
    30601 tctggaacat caagaaatcc tgctgacaat cagtgatgaa gccaaaacgt ggattgctga
    30661 aaatgcttat gaaccagcat atggtgcaag accattgaaa cgatttatca ctaaggaagt
    30721 agaaacacca ctagctaaag aaatcgttgc aggacatgtt atgcctaaat caaaagtaac
    30781 gattacttta cttgatggac aacttcattt caaaacagaa gagctagaag aaatcgtcta
    30841 atcttccatt gagactataa aagaaaaaag gggtctgaca caactagtgt cagacctcct
    30901 tttttcaaat a
//
LOCUS       DAXLPY010000026        29887 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.026, whole genome shotgun sequence.
ACCESSION   DAXLPY010000026 DAXLPY010000000
VERSION     DAXLPY010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.026"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..267)
                     /locus_tag="ACF3UF_001316"
     CDS             complement(<1..267)
                     /locus_tag="ACF3UF_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFD3671458.1"
                     /translation="MKKLALLTLFSTALLVSAPLVSFADETASSSDVTILADDNPVVP
                     VEPTDPTTPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDP"
     gene            complement(327..695)
                     /locus_tag="ACF3UF_001317"
     CDS             complement(327..695)
                     /locus_tag="ACF3UF_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671459.1"
                     /translation="MGKINLNQIYTAKEMSERIGKNRNYLSQAYRNNKHEILKNFNYR
                     KIGGTIIFSDNPNNDLSQLITAKEASQLLGKNDEYFAHIYKRFPHRLEGIDHIYTGKT
                     LFLTKESLEAFKKKMNGNVR"
     gene            complement(724..1692)
                     /locus_tag="ACF3UF_001318"
     CDS             complement(724..1692)
                     /locus_tag="ACF3UF_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671460.1"
                     /translation="MSYYFEIRIILPEEEKQFLNRKLSKSELSEVTHYLQQKTSRGIP
                     VKFRVGIFRVEDQTKIMSVTLNTKNTKETDVINLLLNRVTDQHVLVYLNEPTEPTLNT
                     QELNRQELKTSNERQEIPQTEIPTETVNEPSVIKEISKKNQAKQTNSRKESLSESITK
                     KNVPKIHLFISILTLFIVLLIGISVIQQVQLQSVKKESELLKEQIERVKETDISQSKI
                     DTFGRYFLTYYFSQEKNQENYQSSLRTYVSEKVDIADWKALEKMLKSVNYYGSEQTKK
                     GYSVEYLLNVSVDNRSKMQKITFEVEPTKNGFLVTTQPKLTDFSFN"
     gene            2015..3202
                     /locus_tag="ACF3UF_001319"
     CDS             2015..3202
                     /locus_tag="ACF3UF_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFD3671461.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            complement(3329..4261)
                     /locus_tag="ACF3UF_001320"
     CDS             complement(3329..4261)
                     /locus_tag="ACF3UF_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL family protein"
                     /protein_id="HFD3671462.1"
                     /translation="MDVIDQIKETGSDILSSAGDAISGIFEGVKESVDSVLHPIDSLL
                     GSWGSDLLEASMKIANKTTFDIPNIKLISTITNVFVFATTTFAICIVLYKVIEAQIQA
                     SNGSGDALTANIVQKLFYSSIALATLPWAMNFFIKKIVAPIGEYVIQQVANDLNVETI
                     GERLRNFLVSNFFNGGVSAVVLFVFVIFFAFSIAKYFVAICVFYADFLVLTMLTPLVA
                     LSLLTDEQNYFQIWIKELLSEALTMLIKLILYLLMITLMIAEKYTLPNFMLMVGCGLL
                     IIKTPSALQNMWYSTKVSKGGGLGNLAMMAMFRK"
     gene            complement(4263..5186)
                     /locus_tag="ACF3UF_001321"
     CDS             complement(4263..5186)
                     /locus_tag="ACF3UF_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671463.1"
                     /translation="MNGLKEFFGNIPMFQKQVEREIEEKGIKPSEGIKKMEFSRQVLR
                     NIVIGVLFIGILAFVGISYFNNKNQPPVAPTATTTSKESNQSEASGEATENSSQAVQG
                     SSDHLLKLSAKERADEATEAFESWYKSFSKGDVILEINKELLKEGSGGTSPIELQTKL
                     IDNLKAKFGDKVSDDFYSGLQASFNFNPVIVDGTKGLTISKQNDDQSQWLRTWFLDTE
                     KTAQNTKIILRNDFSYEWADWRNKGQHDEKVGSMFTQIDWANDLRYEVIGIVTSKQEK
                     NIENIGGVFVVMQYNEKIGKWQVSGTIGGVM"
     gene            complement(5204..6859)
                     /locus_tag="ACF3UF_001322"
     CDS             complement(5204..6859)
                     /locus_tag="ACF3UF_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFD3671464.1"
                     /translation="MSSLLAESDGLILGKFQSGNVVIQPEDSKISNRNIFVVGGPGSF
                     KTQSYVLPNVVNNRSTSIVVTDPKGEIYELTNEIKKAQGFKTVVINFKDFLLSSRYNP
                     LLYIRKSNDTNKIANVIVSAKNDPKRKDFWFNAQLNLLNTLIKYVYFEYEPSARTIEG
                     ILDFLEEFDPRYNEEGVSELDEQFERLPDGHEAKRSYYLGFRQAQSEARPNIVISLLT
                     TLQDFVDKEVAEFTSTNDFFFEELGTSKICLYVLISPLDRTWDGLVNLFFQQMFTELY
                     FLGDKHNAKLPVPLVMLLDEFVNLGYFPTYENFLATCRGYRISVSTILQSLPQGFELY
                     GDKKFKAIIGNHAIKICLGGVEETTAEYFSRQVNDTTIKVYTGGTSESKTSAKTTNRS
                     GSKSESYGYQKRRLITEGEVINLQQEENGRKSIVLIDGKPYMLRKTPQFELFGNLLKK
                     HEISQQDYISSQTEFAKEYIEELEVQHKQRKVQLASAPVFHEKKQENDLNKKEIKLPE
                     QPIESEVTEEVEEKEQLMSDILSSFDEGIEENTTNNDNSELPF"
     gene            complement(6852..7283)
                     /locus_tag="ACF3UF_001323"
     CDS             complement(6852..7283)
                     /locus_tag="ACF3UF_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671465.1"
                     /translation="MAKKKQEQVKLIILVILYLLLLPVTLIVFKLLPFIIANDTNIEL
                     STFVTTILKHPINTFLEIIQSNYMIPFFIVQIIVLIILFVFLHPTKRQPFEVVGKTNP
                     VHGSAYWGEESEINAPKNVHLIPEKSMKKILEKSMRRGKNE"
     gene            complement(7288..7839)
                     /locus_tag="ACF3UF_001324"
     CDS             complement(7288..7839)
                     /locus_tag="ACF3UF_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671466.1"
                     /translation="MEFDKIKVSLFISTLALLVVTIGMIVFGIKQGEQIRHLKSDLKS
                     VQTELADKQAEQNTNQSESEKIIKEFYKTVYNYEKSQKEISMTTVKELATDNVYQELQ
                     NEINVNNSYSPQQNTIQKSSVNENEIKILAYASKDNSQQYLVTAPIHQVFNGTKNDFE
                     INQIIQIKNQQITQRTTIQLGEE"
     gene            complement(7852..8961)
                     /locus_tag="ACF3UF_001325"
     CDS             complement(7852..8961)
                     /locus_tag="ACF3UF_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFD3671467.1"
                     /translation="MGATAAKLLIRYRKPIAKAILGFFVFIIVIFLLIFNNDQTAPSG
                     GLATENKNLSESVLRYKSTVEKYARQYDGMEYVPYILALMQIESGGNGGDPMQSSESL
                     GLPPNTIQDPERSIQRGVEFFVENMKSAINRGSDIKTALQAYNYGGGFVDFVVKNGGT
                     YSFELAKQFSINMSGGEKVPYVNALSTSMGYNYRYNYGNMFYVPKLLEYVNESQASAE
                     GVQNNSNNTGAVQVDVPSEYKNKLRYPRYDGHNYNTSGSYPFGQCTWYAFNRMAQIGK
                     PVDDFMGNGGEWGYKGKALGYKVTNKPKVGTAISFPPGSFGSDPVYGHVAFVEVVNAD
                     GTLLVSECNVVNPGSGTISYRVVPASIANIASYVE"
     gene            complement(8983..10335)
                     /locus_tag="ACF3UF_001326"
     CDS             complement(8983..10335)
                     /locus_tag="ACF3UF_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HFD3671468.1"
                     /translation="MKYKILKNLQFYYQENVIVVQINEKYLTNREHIFDVEESEQYFV
                     DVEEILTKDGKLEIVYHRPNGYTPLLDLKEYADFYKLDIVNRLLEMNVLEKTNTYLAM
                     QNILLKDTRDLLFIYKADHFGNLPYSTKEELEQWKNFICSFFGKFSLEKYEKNRIEIL
                     TKEKNSFLNDVEAVESLESLRDLIKNRLTEEQKNFFSAELQDKKANVRKIRRNKSLKI
                     ALVVGVIALYGGTVFLMKVNEKKQVTATQQSAETEITILNKIIDNDSENIEEDMQKLN
                     YPKKKQVDIYVKLGDYTKAYELDKKSDKKIIQSLYKQGETEKIENLDLPGSDYLADFK
                     KILAYDNSTDIEYLVQTSTDTTIVEALIDQAVKKKDIPTVKNIRQVSITQKKLAIDPK
                     RQISMIDLLIENNSEELENIYKDNSLNDDLKKKQTNDLLEENNTLLSEKIELTNAEKD
                     "
     gene            complement(10349..12310)
                     /locus_tag="ACF3UF_001327"
     CDS             complement(10349..12310)
                     /locus_tag="ACF3UF_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="HFD3671469.1"
                     /translation="MEKIPKEKIIVIPEVDTDVVSDLAPFNFTVERDKLLIDDSYAVP
                     YVITKYNNKPRGNWFNRIRKMSGDITISHYYTKANGNSLNDYYNRTIKNKQAEIDRSH
                     DPLTIIRLEREMKIAQTQLEQAVDENTSYLYLYTYVLIKSKSEDKLKKLCEDFETRCI
                     ASGVKALIPYTMIDKAYWSALPLQSNEVPEYTYTIANSISASSIFPFDDNELSVFTKN
                     MIIEGINKDTENIVSIDYTNRKLVVNRNKFVFGLSGGGKTTYLTSDYLKKYAFADNST
                     ELKHRIVLFDPEDEQTERVRSLGGEIINLSSMSDVRINPFQIYSRNTPDVDLKESLSD
                     FEEDELVENLEIKHKDFEMTENDIDKEISKRMNILTPYFLMVDHSLTDSQLSIIKLEA
                     KKCYTTLYEKKNLSKMENTDFPTFSDLESRLKALEETDPKRYKRIEDFIYSLEDFTIG
                     SRTIFNGHTNIDLSNPLICFSLRDLQTEEGIRDLAYLNSFSYLFEEITNNPQIVTSVY
                     ADEFHFLLKNKISADFFFQAYKRFRKYNADCTVSTQQIDDVLKAPDNIGKAIIGNSFT
                     KVFFGLDETEAQGISNELKLKLTKKELSFITSKRQGEALLFHGTKRAKIKVDLTQEEM
                     RLLNPGGYEDIYGVSPKKEINWLLRSKIQ"
     gene            complement(12321..12950)
                     /locus_tag="ACF3UF_001328"
     CDS             complement(12321..12950)
                     /locus_tag="ACF3UF_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671470.1"
                     /translation="MFDFLKKSSKSNDNKKSDTIKEMIYWEDSSRFQGVFKDFFVVYQ
                     PEKKQFSLVSMLKVDGLNVDTLPVSEQEGLNEDFGVFLSQNVLYEPQITSKNVPVEID
                     DFVEAWGNTVENYRKMPGHNEALLQLKASYYYHYRNLASNMETSKKQHFVINSEPISK
                     ETYDSLELSYQVLRDKTRTIRTALIAFLSKYDCQVEICTIGEMKKVLNS"
     gene            complement(12967..13350)
                     /locus_tag="ACF3UF_001329"
     CDS             complement(12967..13350)
                     /locus_tag="ACF3UF_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3671471.1"
                     /translation="MNSDQVKQALLDLLNADTEKGRTWFFPSNVSDRYTVILGLDLKQ
                     SAKAIGTALISVLLAILIFRSTAVFPLIIYVIVGLVSFGGVWAFYTIKPITDRPNISI
                     SDFMKQRKDFSKRPKVYYKKPKERV"
     gene            complement(13369..13701)
                     /locus_tag="ACF3UF_001330"
     CDS             complement(13369..13701)
                     /locus_tag="ACF3UF_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CagC family type IV secretion system protein"
                     /protein_id="HFD3671472.1"
                     /translation="MKKFIKDTKFKLGSAVVALGTLFITDPVFAATDPQAKLVQAGNT
                     IKGVLTALIVVVGGIACAKIVIKYLPSIDDPQEKNTMYKALGTALLVTALGGALVWLV
                     PWAYGLLA"
     gene            complement(13725..15710)
                     /gene="mobQ"
                     /locus_tag="ACF3UF_001331"
     CDS             complement(13725..15710)
                     /gene="mobQ"
                     /locus_tag="ACF3UF_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="HFD3671473.1"
                     /translation="MAIFHLSMTIAKREGGKRSLIAMASYRSGEKLYSELYEKTNLYN
                     HRTVKPEAFILKPDYVPNEFLDRQTLWNKMELAEKQVNSQLCREVNVALPIELNNTDQ
                     RSLIEEFVKDNFVSEGMIADVAIHRDDENNPHAHIMLTMREVDSEGNILNKRKKIPKL
                     DENGNPILLENGKIKMVSIKTNDWDRKSLVSEIRKDWADKVNQYLKDRNIDQQITEKS
                     HAELGKKELPTIHEGFYSKKLEEKGVISELKRKNLEIQSYNDILAELDKLESQEKVLK
                     QDQNFTLKFEKTFSPLEKGELKNLSKEFKLFINDENIDKRLGELKRWENSLIFNNKME
                     IQKQRLMLSKISSERDMLTKANEILDKQAERFFKKSYPSLNIDKFSNHEVRAMVNETI
                     FRKQLLNKDQLAEVIYNERVVEKEESKKIFKEKPFQTSRYLDSKIKQVEDSITKENNP
                     ERKEILSIKKEKLIGIKQGLIEYVQSEVERKFDKNVSIDSVIEGEMLLAKADYYKTTD
                     FSKVEGVARFSSEEINSMLEQSKGFLTNIQTVKIPNDCQGVFFVQDSMKHIDELSPLA
                     KQNLKKVVNRNAYLPDSDKIELSKEIENTNKDQSQELDKDVPEKNEVTVKMFQFAKSI
                     NRLLSGNQLQKKRNLDKLIKQTKAKENQSLQRNIPLR"
     gene            16002..16301
                     /locus_tag="ACF3UF_001332"
     CDS             16002..16301
                     /locus_tag="ACF3UF_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671474.1"
                     /translation="MENQDQNINAINGNFNSKTKPKKRKKKTVSDIELQIKELQKKKE
                     ELILKSKADIGDFVLSTLSKLDISIESIEENKELFYDELETLLNANSQNFSELLK"
     gene            16304..16561
                     /locus_tag="ACF3UF_001333"
     CDS             16304..16561
                     /locus_tag="ACF3UF_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671475.1"
                     /translation="MANNDLNDINKRIEKLKIQKNILRANSEQNINRKRRTKRLIEKG
                     ALLEKYFEIDYLTVEETEEFLKIFSEYIKANKPKKYQKKEK"
     gene            complement(16584..16817)
                     /locus_tag="ACF3UF_001334"
     CDS             complement(16584..16817)
                     /locus_tag="ACF3UF_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671476.1"
                     /translation="MRGINNHQKYDFDLYQIEARSPMSTREITLTVDFIEKKVSGDII
                     AFGDWYDLDIESVNEILKQLKKEGQTLRTINFI"
     gene            17087..17479
                     /gene="merR"
                     /locus_tag="ACF3UF_001335"
     CDS             17087..17479
                     /gene="merR"
                     /locus_tag="ACF3UF_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFD3671477.1"
                     /translation="MIYRISEFADKCGVNKETIRYYERKNLLQEPHRTEAGYRIYSYD
                     DVKRVGFIKRIQELSFSLSEIYKLLGVVDKDEVRCQDMFEFVSKKQKEVQKQIEDLKR
                     IETMLDDLKQRCPDEKQLHSCPIIETLT"
     gene            17504..19144
                     /gene="merA"
                     /locus_tag="ACF3UF_001336"
     CDS             17504..19144
                     /gene="merA"
                     /locus_tag="ACF3UF_001336"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFD3671478.1"
                     /translation="MNKFKVNIQGMTCTGCEKHVESALEKIGAKNIESNFRRGEAVFE
                     LPDDIEVESAIKAIDEANYQAGEIEEVSSLENVALINEDDYDLLIIGSGAAAFSSAIK
                     AIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEINHLSKDNPFKGLQTSAGEVDL
                     ASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDASTVEVNGAKLSAKRFLIA
                     TGASPSLPQISGLEKMDYLTSTTLLELKKIPKRLTVIGSGYIGMELGQLFHHLGSEIT
                     LMQRSERLLKEYDPEISESVEKALIEQGINLVKGATFERVEQSGEIKKVYITVNGSKE
                     VIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEILINDFGQTSNEKIYAAGDVTLGP
                     QFVYVAAYEGGIITDNAIGGLNKKIDLSVVPAVTFTNPTVATVGLTEEQAKEKGYDVK
                     TSVLPLDAVPRAIVNRETTGVFKLVADAETLKVLGVHIVSENAGDVIYAASLAVKFGL
                     TIEDLTETLAPYLTMAEGLKLAALTFDKDVSKLSCCAG"
     gene            19386..20708
                     /locus_tag="ACF3UF_001337"
     CDS             19386..20708
                     /locus_tag="ACF3UF_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3671479.1"
                     /translation="MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKL
                     YKHSSRNQLIMDLPIRLKRVGLQLNRRRYKCRECGSTFWERLISVDEKRSMTKRLLKS
                     IQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRP
                     RLVLTNIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNTILPH
                     AKVVVDKFHVVRMANQALDNVRKSLKAHMSQKERRTLMRERFILLKRKHDLNERESFL
                     LDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGRLCYSQWRHRCMSSNSKDAYKDLVR
                     AVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKR
                     KPRFNSSAFNKAMLYDTFNWYEVNDHDITDNFGVDFSTLIKNLEKGDL"
     gene            20733..20996
                     /locus_tag="ACF3UF_001338"
                     /pseudo
     CDS             20733..20996
                     /locus_tag="ACF3UF_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043131.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(21043..21273)
                     /locus_tag="ACF3UF_001339"
     CDS             complement(21043..21273)
                     /locus_tag="ACF3UF_001339"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671480.1"
                     /translation="MNKVHVYNHNKFVKEINSDTNSIAKEIASQSPFAELKMTDEYDN
                     LILTTKGFFLDDVPNQIWLKNELMPALTNLQI"
     gene            complement(21543..22028)
                     /gene="vanZ-A"
                     /locus_tag="ACF3UF_001340"
     CDS             complement(21543..22028)
                     /gene="vanZ-A"
                     /locus_tag="ACF3UF_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFD3671481.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(22181..23071)
                     /locus_tag="ACF3UF_001341"
     CDS             complement(22181..23071)
                     /locus_tag="ACF3UF_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFD3671482.1"
                     /translation="MLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLENSGTSE
                     NTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDSNIYMS
                     KEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEHNSGL
                     SLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGLPHS
                     AIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEISGN
                     NIDGVIVTVFPGSTHTNSRR"
     gene            complement(23521..24129)
                     /locus_tag="ACF3UF_001342"
     CDS             complement(23521..24129)
                     /locus_tag="ACF3UF_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFD3671483.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(24135..25166)
                     /gene="vanA"
                     /locus_tag="ACF3UF_001343"
     CDS             complement(24135..25166)
                     /gene="vanA"
                     /locus_tag="ACF3UF_001343"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFD3671484.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(25159..26127)
                     /locus_tag="ACF3UF_001344"
     CDS             complement(25159..26127)
                     /locus_tag="ACF3UF_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFD3671485.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            complement(26342..27496)
                     /locus_tag="ACF3UF_001345"
     CDS             complement(26342..27496)
                     /locus_tag="ACF3UF_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFD3671486.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            complement(27474..28169)
                     /gene="vanR-A"
                     /locus_tag="ACF3UF_001346"
     CDS             complement(27474..28169)
                     /gene="vanR-A"
                     /locus_tag="ACF3UF_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFD3671487.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            complement(28441..29754)
                     /locus_tag="ACF3UF_001347"
     CDS             complement(28441..29754)
                     /locus_tag="ACF3UF_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003141076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HFD3671488.1"
                     /translation="MATLHENRLLFNSNVTVSHSGGNLSSDSGLILAKEFMNKFEFSQ
                     ILCKNIQIQDDRLYHVHENESILEQIILQLIAGYPTDSSANILATDPIFQAVLSKKRL
                     ASQSSISRFWDRISTENIVQLQKVNQILIDKARTIRNTNEMIFDLDSTHSDTFGNQEM
                     TDYNAHYQTTGYHPLVAFDGLTGDFLKAELRSGNVYTSKGVAAFTRPLFEHYHSVTPV
                     STIMVRADSGFAMPDLYELCEEYDSLYTIRLKSNRNLYRIADQFITIKDHHDWSKKEV
                     HYYNATYQAKSWGKSRRICIKSTREASELLFRHEFIITNFSKDVSPEMVFQTYSKRGT
                     MENYIKEAKNGFYLDKTDSPRFIENHARMIVSLLAYNIVNFMRTLCFTNETKGYQVST
                     IRLFLFKIAGKIVHSGRRQYLKLSSYHVYQKLFYRILQNIQVLQC"
BASE COUNT         8897 a         5549 c         5041 g        10400 t
ORIGIN      
        1 tggatcgact ggatcgactg gatcaactgg atcgactgga tcaactggat caactggatc
       61 aactggatcg actggatcga ctggatcaac tggatcaact ggatcaactg gagtagtcgg
      121 gtctgtcggt tctactggaa cgactggatt atcatcggct aagatagtaa catcactgct
      181 acttgcggtt tcgtctgcaa aactgacaag cggtgctgat actaataatg cagtgctgaa
      241 tagtgttaag agggctaatt ttttcatttt ataatctcct taaaaattag tatttgtgta
      301 cataaatagt atatcataaa tatgctttat ctgacatttc cattcatctt ttttttaaaa
      361 gcttctagcg attctttcgt taagaataat gttttacctg tataaatgtg atcgattccc
      421 tctagtctat gaggaaaccg tttataaatg tgggcaaagt attcatcatt ctttcctaac
      481 aactgacttg cttcttttgc tgtaatcaat tgcgataaat cattattggg attatcagag
      541 aaaataattg ttccaccaat ttttcgataa ttaaaatttt taagtatttc atgtttgttg
      601 ttacggtaag cttgggatag gtaatttcta ttcttaccta tccgttcact catttctttt
      661 gctgtgtaaa tttgatttaa attaattttt cccattgttt aagcactctc tttttagcgt
      721 atttcagtta aaagagaagt ctgtaagttt tggttgagtt gtcacaagaa agccgttttt
      781 agttggttca acctcaaaag tgattttttg cattttacta cgattgtcta ctgaaacatt
      841 tagaaggtat tcaacgctat accctttttt tgtttgttca ctaccatagt aattgacact
      901 cttaagcatt ttctctaacg ctttccaatc agctatatct accttttcgg atacatatgt
      961 tcttaaactt gactgataat tttcttgatt tttttcctgt gaaaaatagt aagtcaaaaa
     1021 gtatcttcca aaagtatcta ttttcgattg agaaatatcc gtttctttga cacgttcaat
     1081 ttgttctttc aataattcgc tctctttttt gactgattga agttgtactt gttgaataac
     1141 acttattcct atcaataata caataaaaag agtcaaaata gatatgaaca aatgaatttt
     1201 gggaacattt ttcttggtta tggattctga tagtgattct tttctactat tcgtttgttt
     1261 tgcttggttc tttttcgata tttccttaat aacactaggt tcatttactg tttcagttgg
     1321 aatttctgtc tgcggtattt cttggcgttc attactcgtt tttaactcct gacgatttaa
     1381 ttcttgcgta ttaagcgttg gttctgttgg ttcattcaag taaactaaaa cgtgttgatc
     1441 tgttactcga tttaataaca agttaattac gtccgtttct ttggtatttt ttgtattcag
     1501 cgtaacagac ataatttttg tttgatcttc tactctaaaa atacctacac gaaatttaac
     1561 tggaattcct cgacttgtct tttgttgtaa atagtgtgtg acttcggata attcgctttt
     1621 acttaatttt cgattcaaaa attgtttttc ttcttcggga agaataattc gtatttcaaa
     1681 ataataagac aatcgttatc ccccttgtat attagagtta gggttttaac cttccggttt
     1741 tgattggata accctatgaa ccatcgttat tttaatttgg tattaactca tttcttttga
     1801 gataatatat ttattggatt gagaggctaa gccgttcccc ccttgggtca ttgaacccgc
     1861 actcgagaga ctggctcctc tctctgataa gtggattgcg tatgagttag atgttgaaag
     1921 tccttacttt actccgtatc tcgtacaagg tagtgacgct tttcagttga gtggatttca
     1981 atccaaaatt ctttttttga aaggtcagat atacatgtac tttttaggca ttgatatcgg
     2041 taaacgcact cacgttgctt ctatcatgaa cgaggaagga aaggtattac taaaaggttt
     2101 ttcatttcct aacaccactg aaggagcaga gtcattaatt gagcgaatgg tcgactattc
     2161 cggagcaccc agtgactttg ttatagggat ggaagccacg gggcactatt ggctgtccat
     2221 cttttcatac cttcacgaat cagattattt gattcacgtt gtgaatcccc ttcaaacaga
     2281 cggatggcgt aaaggtacag aaatacggaa acgaaaaaac gatattattg attctgtttt
     2341 gattgctgac ttaatgcgct atggctcatt tgtcgaaacg gtcttatccg atgaaaatgt
     2401 tttttctttg aaacaacttt ctcgttaccg aacttattta gtaggtacag cgagcgactt
     2461 caaaagaaaa attatagccg tattggatca agtctttcca gaatacgcga cgatttttac
     2521 caagcagggc gttttcggaa aagcttctaa agagttattg ctggcgttta gtgccccgat
     2581 cgacttagaa aacatttcct cagaaacttt ggcccaatac ttagctgagt taagcaggaa
     2641 ccgaatcaag gcagaaaaag cggaccaatt gaagcaagca gcttctaact cctttggagt
     2701 aaaatttgct caagaagcgt tcaccttcca actacgttca atgattgaac aattaaaatt
     2761 cattgaaagc caaataaagg aaacggaaag agaaatcaag cacataatgg acactttaaa
     2821 ttctgttatt ctcacaattc ctggaattgg tcctataaac ggtgcgacta ttcttggtga
     2881 gatcggagat attcaaaaat tttctaaccc gaaaaaactc gttgcttacg ctgggataga
     2941 cgcttccgtg acacaatcag ggcaatatga ggcaacgcat aatgttatga gtaaacgagg
     3001 gtctccatat ttgcgaaaag ccttgttttc ggcggcttta gtagcttctc aatgtgatcc
     3061 tgtttttagt gcgttttacc agaaaaaagt ttccgaagga aaacatcatc taactgcctt
     3121 aggtgcggtt tctcgtaagc tttgttacgt gattcatgct attttgacta aaaacgagcc
     3181 ttatataatt gtttctgatt agctattgaa cattcaaaaa aactaatggt aagaagctta
     3241 tttgttgtac ccttttttcg gaattatctg ttataaaata ttttttgatt tggctaattt
     3301 ttacttgact ctatatagtt agtctctctt attttctaaa catagccatc attgctaagt
     3361 ttccaagtcc gccacctttt gacactttgg ttgaatacca catattttgt agggctgacg
     3421 gtgttttgat aatcaacaag ccacaaccaa ccattaacat aaagtttggt aacgtgtatt
     3481 tttcagcaat catgagtgta atcatgagta agtacaaaat aagcttaata agcattgtga
     3541 gtgcttcgga taacagttct ttgatccata tttgaaagta attttgttcg tctgttaaaa
     3601 gcgataaggc aactaatggt gttaacatag tcagtaccaa gaaatcggca taaaagacac
     3661 agatcgctac aaaatacttg gcaatggaaa aggcaaagaa tatcacgaaa acaaagagaa
     3721 caacggcgct aacgccacca ttaaagaaat ttgatactaa gaaattacgc aatcgttcgc
     3781 cgatcgtttc cacattcaaa tcattagcga cttgttgaat cacatattcc ccgattggtg
     3841 caacaatctt tttgataaaa aagttcattg cccagggcaa cgttgctaag gcaatagacg
     3901 agtaaaacag cttttgaaca atattagcgg tcaatgcgtc accactccca ttagaagctt
     3961 gtatttgcgc ttcaatgacc ttatacaaca caatacaaat tgcaaaggtc gtagtggcaa
     4021 agacaaacac gttggtaatg gtgctaatta attttatatt tggaatatca aaagttgtct
     4081 tattcgcaat tttcatgctt gcttctaaaa ggtcgcttcc ccaactgcct aataaactat
     4141 cgatcgggtg caaaacacta tctacactct cttttacgcc ttcaaatatt cctgatatgg
     4201 catcaccggc agaacttaaa atgtctgatc cggtttcttt tatttggtca attacgtcca
     4261 tattacatta caccaccaat cgttccgcta acttgccact ttccaatttt ttcgttgtat
     4321 tgcataacta caaatactcc accaatattt tctatatttt tttcttgttt gctggttact
     4381 atccctataa cttcatatct taaatcatta gcccaatcaa tttgtgtaaa cattgatcct
     4441 actttctcat catgttgtcc tttgtttctc caatctgccc actcataaga aaaatcattg
     4501 cgtaggataa ttttggtatt ttgcgctgtt ttttcagtgt ctaagaacca agtccgtaac
     4561 cattggcttt gatcgtcatt ttgcttggaa atcgttagcc cttttgtacc gtcaacgatt
     4621 actggattga aattaaagct tgcttgtaaa cctgaataga aatcatctga aactttatcg
     4681 ccaaacttgg cttttaagtt atcaatgagt tttgtttgta actcaatcgg gcttgttccg
     4741 cctgatcctt ctttcaataa ctctttgttg atctctaaaa tcacgtcacc ttttgaaaat
     4801 gacttgtacc aactctcaaa agcttctgtc gcttcgtctg ctcgttcttt ggcacttaat
     4861 ttgagtaaat ggtcgcttga cccttgaacg gcttgtgagc tgttttctgt agcttctccg
     4921 cttgcttccg attggttact ttctttgctt gtggtggtgg cggttggtgc tactggtggt
     4981 tgattcttat tgttaaaata agaaatacca acaaaggcaa gaatgccaat aaacaagaca
     5041 ccaatcacta tgtttctaag cacttgacgg ctaaattcca tttttttaat accctcgcta
     5101 ggtttaatcc ctttttcttc gatttctcgc tcaacttgtt tttgaaacat tgggatattc
     5161 ccaaaaaatt ctttcaatcc attcatttga tttcctccga tctttaaaat ggtaattcgc
     5221 tgttgtcatt gttggttgtg ttttcctcta taccttcatc aaaactactt agaatatcac
     5281 tcattaattg ttctttttct tctacttctt ctgttacttc tgattcgatc ggttgttcag
     5341 gtaatttgat ttctttttta tttaagtcat tttcttgttt cttctcatga aaaactgggg
     5401 cgcttgcgag ttgtactttt ctttgcttgt gctgtacttc caattcttca atgtattctt
     5461 tggcaaattc tgtttgactg cttatataat cttgttgtga aatttcatgc tttttaagaa
     5521 gatttccgaa caattcaaat tgtggcgttt ttcttaacat gtaaggttta ccgtcaatta
     5581 acacaatact ttttcttcca ttttcttctt gttgtaaatt gataacttcc ccttcggtaa
     5641 ttaatcgcct tttttggtaa ccgtagcttt ctgacttact tccgcttcgg ttagttgttt
     5701 ttgcggacgt tttactttca cttgttccgc ctgtatatac cttgattgtt gtatcattta
     5761 cttgtcttga aaagtattca gcggttgttt cctctacacc acctagacaa attttaatgg
     5821 catgattccc aatgatcgct ttaaatttct tatctccgta tagttcaaag ccttggggca
     5881 atgactgtaa aatggtacta actgaaatac gataccctcg acatgttgca agaaaattct
     5941 cgtatgttgg aaagtagccc aaattgacaa attcatctag taacataact aaaggtactg
     6001 gcaattttgc gttgtgctta tcccctaaaa aatataactc tgtaaacatt tgttggaaaa
     6061 agagattcac taagccgtcc caagttcgat ctaatgggga aattagcacg tataaacaaa
     6121 tttttgacgt tcctaattcc tcaaagaaaa aatcgtttgt actggtaaat tctgctactt
     6181 ctttatcaac aaaatcttgt aaagtcgtca atagactaat aacaatgttt ggtcttgctt
     6241 cactttgtgc ttgtcggaag cctaaatagt aactgcgttt tgcttcgtgt ccgtctggca
     6301 aacgctcaaa ttgttcatca agttctgata caccttcttc gttatagcgt ggatcaaatt
     6361 cttctaaaaa gtctaaaata ccctcaattg ttcttgcgct tggttcatat tcaaaataaa
     6421 catatttaat cagtgtattt aataagttta attgtgcatt gaaccaaaaa tctttccgtt
     6481 tgggatcatt ctttgctgat actatgacgt tcgcaatctt gtttgtatca tttgatttgc
     6541 gaatgtaaag taatggattg tacctagaac ttagtagaaa atctttaaaa tttatgacaa
     6601 ccgttttgaa gccctgggct ttttttattt cattggttaa ctcgtaaatt tccccttttg
     6661 gatcggttac aacaattgac gtactgcgat tatttacaac attaggcaaa acataacttt
     6721 gtgttttaaa tgatcctgga ccacctacta caaaaatatt tcgattgctt attttgctat
     6781 cttcgggttg gatcacaaca tttccgcttt gaaatttccc taagattaaa ccgtctgatt
     6841 ctgctaacaa actactcatt tttccccctc ctcattgact tttctaatat ctttttcatt
     6901 gacttttcag ggatcaaatg aacatttttt ggtgcgttta tttctgattc ttccccccaa
     6961 taagccgatc catgaacagg gtttgttttc ccgacaacct caaacggttg gcgtttggta
     7021 gggtgaagaa agacaaataa aataattaaa acaatgattt gtacaatgaa gaacggaatc
     7081 atgtaattag attgaatgat ctctaaaaaa gtattgatcg ggtgctttaa aatagttgta
     7141 acaaaggtac tcaattcaat atttgtatca ttcgcaatga taaaaggtaa taatttaaac
     7201 acaatcaatg ttactggtaa taatagtaga tagagtataa ctaggataat cagttttact
     7261 tgctcttgct ttttcttcgc catgcttcta ctcctctcct aattgaatgg tcgttctttg
     7321 agtaatttgt tggtttttaa tttggataat ttggtttatt tcaaaatcat tttttgtacc
     7381 gttaaaaacc tggtgaatcg gtgctgttac tagatattgc tgtgaattat ccttacttgc
     7441 ataagcaaga atttttattt cattttcgtt tactgaagac ttttgaatcg tgttttgttg
     7501 tgggctatat gaattgttta cgttgatctc gttttgtaat tcttgataaa cgttgtctgt
     7561 cgctaattct ttaaccgttg tcatagatat ttctttttgg cttttttcgt agttataaac
     7621 ggtcttgtaa aattctttga taattttttc cgattcgctt tggttagtgt tttgttccgc
     7681 ttgtttgtct gctagttccg tctgtacgct ttttaaatca ctttttaagt gacggatctg
     7741 ttcgccttgc tttattccaa aaacaatcat gcctatggta accacaagta aagcaagcgt
     7801 tgagataaac aaactaactt ttattttgtc aaactccatt tttttctctc cttattcaac
     7861 ataacttgca atgtttgcaa tagaagctgg cactactcga taactgattg ttccacttcc
     7921 tgggtttact acattacact ctgatacaag aagcgtaccg tctgcattta cgacttctac
     7981 aaaggcaacg tgtccgtaaa ctggatcaga accgaaagaa cctggaggga aagaaattgc
     8041 cgtacctact ttgggcttat ttgttacttt atagcctaaa gctttccctt tatagcccca
     8101 ttcgccacca ttgcccataa aatcatcaac tggttttcct atttgagcca tacgattaaa
     8161 agcgtaccaa gtacattgcc caaatggata actaccgctt gtgttatagt tgtgtccgtc
     8221 atatcttgga taacgtaatt tatttttgta ctcactaggt acatcaactt gaacagcgcc
     8281 agtattatta gaattgtttt gaacgccctc tgcgcttgcc tggctttcgt taacgtattc
     8341 aagtaatttt ggcacataga acatatttcc gtagttatag cggtaattgt agcccattga
     8401 agtagataaa gcatttacat aaggtacctt ttcgccacct gacatattaa tagaaaattg
     8461 tttagccaac tcaaaagaat acgttccgcc attcttcact acaaaatcaa caaaaccacc
     8521 gccataattg tacgcttgaa gagctgtttt tatatctgat cctcggttta tagcgctttt
     8581 catattttct acaaaaaact ctactcctcg ttgtatgctt cgttcggggt cttgaatggt
     8641 gttagggggc aatcctaaac tttcgcttga ttgcatagga tcgccaccat tcccgcccga
     8701 ttcaatttgc atgagtgcta agatataagg tacatattcc ataccgtcat attgtctagc
     8761 gtacttttca acggtacttt tgtacctcaa aacagattca cttaaatttt tgttttctgt
     8821 tgctagtccg ccactagggg cggtttgatc gttattaaaa ataagaagga agattacaat
     8881 gataaagacg aaaaagccta aaattgcttt cgctatcggt tttcgataac gaataagcag
     8941 tttagcagct gttgctccca tgatatgaaa tcaccaacct tcctaatctt tttcagcgtt
     9001 tgttaattca atcttttcac taagcaatgt gttgttttct tctaacaagt cattggtttg
     9061 ttttttcttc aagtcgtcat ttaaagaatt atccttatat atattttcta gttcttcact
     9121 gttattttca atcaataagt caatcatgct gatttgacgt ttaggatcga ttgctaattt
     9181 cttttgtgta attgatactt gacgaatatt ttttactgtt ggaatatcct ttttctttac
     9241 cgcttgatcg attaaagctt caacaattgt tgtatcggta cttgtctgaa ccaggtactc
     9301 aatatctgtt gaattgtcat acgctaaaat ctttttgaag tctgctaaat agtcgcttcc
     9361 tggcaaatca agattttcta ttttttcggt ttccccttgt ttgtacagac tttgaataat
     9421 ttttttatct gactttttat caagttcata agccttagtg tagtcaccaa gtttcacgta
     9481 aatatcaact tgttttttct taggatagtt gagtttttgc atatcttctt cgatattctc
     9541 actatcatta tcaataatct tatttaaaat agtgatctct gtttctgcgc tttgctgtgt
     9601 agccgtaact tgttttttct catttacttt cataagaaaa accgtaccgc catataacgc
     9661 aataacacct acaactaacg caatttttaa gcttttattt ctgcgaattt ttcggacgtt
     9721 tgctttctta tcctgtaatt cagcagaaaa gaaattcttt tgttcttcgg ttagtcgatt
     9781 ttttattaaa tctcttaatg attccaaact ttcaactgct tctacatcat ttaaaaatga
     9841 atttttttct tttgttagaa tctcaatacg attcttctca tacttttcaa gcgaaaattt
     9901 accaaaaaaa ctacaaataa aatttttcca ctgctctaat tcttctttag ttgagtaagg
     9961 caaattacca aaatgatctg ctttataaat aaaaagcaag tcacgtgtat ctttgagtag
    10021 gatattttgc attgctagat aggtgtttgt tttttctagt acattcattt caagtaatcg
    10081 attcactata tccaatttat aaaaatcagc atattctttt aaatcaagta gtggtgtata
    10141 gccattagga cggtgataaa caatttctag ttttccgtct ttggttaaaa tttcctcgac
    10201 atcaacaaaa tattgttcac tttcttctac atcaaaaata tgttctcgat tcgtcaaata
    10261 tttttcgttt atttggacga caatgacatt ctcttgatag tagaattgta aatttttcaa
    10321 gattttgtat ttcatttttt tctcccttct attgaatttt cgatcttaac aaccaattga
    10381 tctctttctt cggactaacg ccgtaaatat cttcatatcc gcctgggtta agcaaacgca
    10441 tttcttcctg ggtcaaatcg actttaattt tagccctctt tgttccatga aagagtaaag
    10501 cttccccttg acgttttgag gtaatgaaag ataattcttt ttttgtaagt ttaagtttca
    10561 actcgtttga gataccttgc gcttccgttt catcaagtcc aaagaacact tttgtaaagc
    10621 tattcccaat aattgcttta ccgatattat caggtgcttt taatacatca tcaatctgtt
    10681 gggttgatac ggtacaatcg gcgttatatt ttctaaagcg tttgtaagcc tggaagaaaa
    10741 aatctgcact aattttattt ttcagtaaaa agtgaaattc atctgcataa acagacgtta
    10801 caatttgcgg attgttggtt atttcttcaa atagataact aaagctgttg aggtatgcta
    10861 aatctctgat tccttcttcg gtctgtaaat ctcgcaaaga gaagcaaatt aacggattgc
    10921 ttaagtcaat atttgtatga ccgttaaata tggtacggct tccgattgta aaatcttcta
    10981 atgaataaat aaaatcttca attcgcttgt atcgtttggg atcagtttct tctaatgctt
    11041 tcaatcgact ttctaagtct gaaaatgttg gaaaatcggt gttttccatt tttgacaagt
    11101 ttttcttttc gtataaagtg gtatagcatt ttttcgcttc taacttaata atagataatt
    11161 gactgtcagt caaagagtga tccaccatta ggaaatatgg cgttaaaata ttcattcgtt
    11221 tactgatttc tttatcaata tcattttcag tcatttcaaa atctttgtgc tttatttcaa
    11281 gattttctac aagttcgtcc tcttcaaaat cggataacga ttcttttaaa tccacatctg
    11341 gtgtattgcg tgagtagatt tgaaacggat tgatacgaac atctgacata gacgaaagat
    11401 tgattatttc gccccctaga gaacgtacac gttctgtttg ttcatcttcg ggatcaaata
    11461 aaacaattct gtgttttagt tctgttgagt tatcagcaaa agcatatttt ttcaaatagt
    11521 ctgacgttag gtaagtggtt tttcccccac cagataaacc aaaaacgaat ttattacgat
    11581 tgactactaa ttttctgttg gtgtaatcaa tactaacgat attttcagta tctttattaa
    11641 ttccctcaat aatcatattt ttagtaaata cacttaattc attatcatca aaaggaaaaa
    11701 tactgcttgc actgattgaa ttagcgattg tgtacgtgta ttcaggcact tcattagatt
    11761 gtaaaggtaa ggcactccaa tacgctttat caatcatagt atatggaatc aaggctttta
    11821 ctccacttgc gatacaacgt gtttcaaaat cttcacacaa ttttttcagt ttatcttcgg
    11881 acttactttt gatcaaaaca taggtatata aataaagata agaagtgttt tcgtcaacgg
    11941 cttgttctaa ctgcgtttgt gcaattttca tttcacgttc taaacggata atcgtcaacg
    12001 gatcatgcga acgatcgatc tctgcttgct tgttcttaat ggttctgttg taataatcat
    12061 tcaatgagtt accgtttgct ttagtgtaat aatgagatat ggttatatct ccactcattt
    12121 tacgaatacg attaaaccaa tttcctcttg gtttattatt gtattttgta atgacatagg
    12181 gaactgcgta tgaatcatca atcaataatt tgtcacgttc tactgtaaag ttaaatggtg
    12241 ctaaatcaga tacaacgtcc gtatcaactt cgggtattac aataattttc tcttttggta
    12301 tcttctccat tttaacgctc ctaactattc aaaacctttt tcatctcgcc aatcgtacaa
    12361 atttcaacct gacaatcata tttacttaaa aatgcaatta aagctgttct gattgttctt
    12421 gtcttatcac gtaacacttg ataagacaat tccaaactgt cgtatgtttc ctttgaaatt
    12481 ggttcagaat taattacaaa atgttgtttc tttgaagttt ccatgttact tgctaaattt
    12541 ctgtaatggt aataatagct agcttttagt tgtaataaag cttcgttatg ccctggcatt
    12601 ttgcgataat tttctactgt attcccccag gcttctacaa aatcgtcaat ttctactggt
    12661 acattcttag aagtgatctg cggttcatat agaacgtttt gagatagaaa gacaccaaaa
    12721 tcttcgttta acccttcttg ctctgatact ggcaatgtat caacgtttaa gccgtcaact
    12781 tttagcatac tcacaaggct aaattgcttt ttttctggct gataaacgac aaaaaagtct
    12841 ttaaaaacgc cttgaaatcg ggaactatct tcccaataaa tcatttcttt tatcgtatcg
    12901 ctttttttat tatcgttact tttggaactt ttttttagaa aatcaaacaa tgaaatcacc
    12961 tctcttttac actcgttctt ttggcttttt gtaatagact tttggtcttt tagaaaagtc
    13021 ttttctttgc ttcataaaat cagatataga aatgttaggt cggtctgtaa ttggtttaat
    13081 cgtataaaac gcccatacac caccaaatga caccaaacca acaatgacat agataattaa
    13141 aggaaaaacg gctgtgctac ggaaaataag aattgccaat agcacgctta ttaatgccgt
    13201 accgatcgct tttgctgatt gttttaaatc tagccctaaa atgactgtgt accgatcaga
    13261 tacattggac ggaaaaaacc aagtccgccc tttttcagtg tctgcattta acaaatctaa
    13321 tagggcttgt ttcacttgat cgctattcat aactaactcc cttctctatt aagcaagtaa
    13381 gccatacgcc caaggtacta accaaaccaa cgccccacct aatgccgtaa caagcaaggc
    13441 tgttcccaag gctttataca tggtattttt ttcttgtggg tcatcaatag acggcaagta
    13501 tttaataaca atcttcgcac aagcaatccc accaactaca acaattaagg ctgttaaaac
    13561 accttttata gtgttacccg cttgaactaa tttcgcttgt ggatcagtgg ctgcaaacac
    13621 tggatcagta ataaacaatg tacccaacgc aacaaccgca cttccaagct taaactttgt
    13681 atctttgata aattttttca ttttatacac ctcttgtttt tattttatcg caaaggaata
    13741 ttcctttgta atgattgatt ttcttttgct tttgtttgct taatcaattt gtctaggttt
    13801 cgttttttct gtagttggtt accactcaac aaacgattaa ttgacttcgc aaattggaac
    13861 atttttacag tcacttcatt tttttctggt acgtctttat ccaattcttg ggattgatct
    13921 ttattggtat tttcaatttc tttacttaat tctatcttat cagaatcagg taaataagca
    13981 ttgcgattaa caaccttttt cagattttgt tttgctaatg ggcttagttc atcaatatgt
    14041 ttcatgctat cttgaacaaa aaatacacct tgacaatcat taggaatttt caccgtctga
    14101 atattagtta agaagccttt tgattgttcc aacatggaat taatttcctc actgctgaat
    14161 ctagcaactc cttcgacttt agaaaaatca gttgttttgt aatagtcagc ttttgcaagt
    14221 aacatttcgc cttctatgac tgaatctatt gaaacatttt tatcaaattt tctttcaact
    14281 tctgattgaa catattctat caatccttgt tttattccta ttagtttttc tttcttaatt
    14341 gataaaattt cttttctttc agggttattt tcttttgtta tactatcttc aacttgttta
    14401 atttttgaat caagataacg gctagtttga aatggttttt ctttaaaaat ctttttactt
    14461 tcttcttttt ctactactct ttcattgtaa atgacctctg ctaactgatc tttattcaat
    14521 aactgttttc taaatatggt ttcattaacc attgctctaa cttcgtgatt tgaaaatttg
    14581 tcaatattca aacttggata agattttttg aagaatcttt ctgcttgttt gtctaaaatt
    14641 tcatttgcct ttgtaagcat atctcgttca ctactaattt tacttaacat caaacgttgt
    14701 ttttgaattt ccattttatt attaaagata agtgaatttt cccatcgttt taattcacct
    14761 aatcgtttat caatgttttc atcattaata aataatttaa attcttttga aagatttttc
    14821 agttctcctt tttccaaagg tgagaaagtt ttttcaaatt ttaaagtgaa gttttggtct
    14881 tgttttaaca ctttctcttg actttcaagt ttatcaagtt cggctagaat atcattgtaa
    14941 ctttgaattt ctaaattttt tctttttaac tcacttataa ctcctttttc ttctaatttt
    15001 tttgagtaaa aaccttcatg aattgttggt agttcttttt ttccaagttc cgcatgcgat
    15061 ttttctgtaa tttgttgatc gatatttcta tcttttaaat attggttgac tttatcagcc
    15121 caatctttac gaatttcaga aacaagagat tttctatccc aatcatttgt tttaatagaa
    15181 accattttaa ttttaccatt ttctaataaa atcgggtttc cattttcatc tagtttaggt
    15241 atcttttttc gcttgttaag aatatttcct tcactatcta cttctctcat tgttagcata
    15301 atgtgagcat ggggattgtt ttcatcatct ctatggatag ctacatctgc aatcattcct
    15361 tcgctgacaa aattatcttt aacaaattct tctatcagtg atcgttgatc tgtattattt
    15421 aattcaattg gcaatgctac atttacttct cggcaaagtt gagaattcac ctgtttttct
    15481 gctaattcca ttttgttcca taaagtctgt ctatctaaaa attcattagg tacataatca
    15541 ggctttaaaa taaaagcttc tggtttaaca gttctatggt tgtatagatt agttttttca
    15601 tatagttcac tatacaattt ttcaccgctt cgataagaag ccattgcaat taaacttctt
    15661 tttccgcctt ctctttttgc tattgtcata gataaatgga agattgccaa ttgtatcacc
    15721 tctctttctt ttcaaacatg agcgtagcga attttaacaa acacgcttga cgataaaacg
    15781 aaatgtaaat taagttttat agcacaatta ccactaaatg aaatttaggg gtataagtgc
    15841 gcccttagta aatcatctaa gggaatcctt gataaattaa ttttaccact tatcattata
    15901 aaagtaaata tgtttaatct gacattttca tttatattta ttgattttag aaaaataata
    15961 taatatgata gagttacata atatattagg aggcgtattt catggaaaat caagatcaaa
    16021 atattaatgc aattaatggt aattttaatt ctaaaactaa gcccaaaaaa agaaagaaga
    16081 aaactgtttc tgatattgaa cttcaaatta aagaattaca aaagaaaaaa gaagaattaa
    16141 ttctaaaatc aaaagcagat attggtgatt ttgtcctttc tactctttca aaacttgata
    16201 tttctattga atcgattgaa gaaaacaaag aattattcta tgacgaatta gaaactttat
    16261 taaatgcgaa tagtcaaaat ttttctgaat tacttaaata gttatggcaa ataatgattt
    16321 aaatgacatc aacaaaagaa tagaaaaact aaaaattcaa aaaaatattt tgcgagcgaa
    16381 tagcgagcaa aatattaaca gaaaaagaag aacaaaacgt ctaattgaaa aaggtgcttt
    16441 gttagaaaag tattttgaaa ttgactattt aactgtagaa gaaacggaag aatttttaaa
    16501 aattttttct gaatatatta aagcgaataa acctaaaaag tatcaaaaaa aggaaaaata
    16561 attttccttt ttttgatact tttttaaata aaattgattg ttcttaatgt ttgtccttcc
    16621 ttttttaatt gctttaatat ttcatttact gattctatat ccaaatcgta ccaatcacca
    16681 aaagcgataa tatcacctga tacttttttt tctataaaat caactgttaa agttatttct
    16741 cttgttgaca ttggcgaacg tgcttctatt tgatataaat caaaatcgta tttttgatga
    16801 ttatttattc ctctcatttc tgttactgtc gcttttataa cttttaaaat attaccttca
    16861 aaatttattt tgggtcttcg gaatatatag tggaattact ttcttaatag tttaaaaaca
    16921 actggtgttt aaatcggatt ttctggtggg atgttaggac aatcaatagt attatataaa
    16981 agtatcaatc acatacgagt gatacgttgg ggaaaaataa aatagtccaa tttacttgac
    17041 cgcgtactat ggtacacggt ttataatatt catggggtga aataagatga tttatcgcat
    17101 tagtgagttt gcagataaat gtggagttaa taaagaaacg attagatatt acgagagaaa
    17161 aaatttatta caagaacctc accgaacgga agctggttat cggatatatt catatgatga
    17221 cgttaagcgt gttgggttta ttaaacgaat acaggaactt agtttttctt taagcgagat
    17281 ttataaatta cttggtgttg tagataaaga tgaagttcgt tgtcaagaca tgttcgaatt
    17341 tgtttctaaa aaacaaaagg aagtgcaaaa acaaatagag gatttaaaac gaattgaaac
    17401 tatgttagac gacttaaaac aacgatgtcc agatgaaaag caattacatt cgtgtccaat
    17461 aatagaaaca ttaacatgag acattaacga aaggggcttt tttatgaata aatttaaggt
    17521 aaacattcaa ggaatgactt gtacgggttg tgaaaaacac gtagaatcag cacttgaaaa
    17581 gataggtgct aaaaatattg agtctaattt tcgtcgtggt gaagcagtat ttgaactgcc
    17641 cgatgatatt gaggttgaaa gtgcaataaa ggcgattgat gaagcaaatt accaagccgg
    17701 agaaattgaa gaagtatcat cactagaaaa cgtggcgtta attaatgaag atgattatga
    17761 ccttcttatt attggttctg gtgctgctgc cttttcttcg gcaattaaag ctatagaata
    17821 cggtgcaaaa gttggaatga ttgagcgtgg aacggttggg ggaacctgtg tgaatattgg
    17881 ctgtgttccg tcaaaaactc ttcttagggc aggggaaatc aatcatttat caaaagacaa
    17941 tccgtttaaa ggtttacaaa catccgctgg agaagtggat ttagctagtt taatcacgca
    18001 aaaggataaa ttggtgagcg aacttcggaa tcaaaaatat atggatttaa ttgatgaata
    18061 taattttgat ttaattaaag gtgaagcaaa attcgttgat gctagtacgg ttgaggtcaa
    18121 tggggcaaag ttatctgcaa aacgcttttt aattgcaaca ggtgcatcgc cttcgttgcc
    18181 ccaaatttca ggacttgaaa aaatggacta tttaactagt acaacacttc ttgagttaaa
    18241 gaaaatacca aaacgattaa ctgtaattgg ctcaggatac attggaatgg agcttggaca
    18301 actatttcat catttaggtt cagaaataac gcttatgcaa agaagtgagc gacttttaaa
    18361 ggagtatgat cctgagattt cagagtcagt tgaaaaagcg ttaattgaac agggtataaa
    18421 ccttgtcaaa ggggcaactt ttgagcgtgt tgaacaaagt ggagagataa aaaaggttta
    18481 cataacagta aatggcagta aagaagtcat tgaatcagat cagttacttg ttgccactgg
    18541 aagaaaacca aatacggatt ctttaaattt aagtgcagca ggtgttgaaa ctggaaaaaa
    18601 taatgaaatc ctgatcaatg attttggtca aacaagtaat gaaaagattt atgcagcagg
    18661 agatgtgacg ttaggaccgc aatttgtata tgtagcagcc tatgaaggtg gaattattac
    18721 tgataatgct atcggtggat taaacaaaaa aatagattta tcggtagttc ctgctgttac
    18781 gtttacgaat ccgacggttg caacggttgg tttaacagaa gaacaagcaa aagagaaagg
    18841 gtatgatgtg aagacatctg tattaccttt agatgctgtt ccaagagcaa ttgtaaaccg
    18901 tgaaacaacc ggtgtattta aactagtagc agatgcagaa acactaaaag tattaggggt
    18961 tcatattgta tctgagaatg caggagatgt catctatgca gcatcattag ctgttaaatt
    19021 tggcttaacg atagaagatt taacagaaac cctagcacca tatttaacaa tggctgaagg
    19081 gctaaaatta gctgcactta cgttcgataa agatgtttcg aaattatctt gttgtgcagg
    19141 ctaagggaac tttttttaca actccctatt caagtgaacc agctaatact gtactaaagg
    19201 tgtgcagtag tttagcaaag tctacaaaag atttcataca ctattttgcg atcacccatt
    19261 atataaatgc tttaagggat tttctaagtg catttgtggt cacaaaaata atttaacaat
    19321 gatgatttcg acatcaaatc tataattgat accttaacac cgcagagtaa taaaggatga
    19381 acaatatgtc agacttatta tccctaccag acattaaaac aatagaacca ccacaagaaa
    19441 atgaaaccga tatgatgttt aaagttgaag cagtcggacc acctgaacgt tgtcctgaat
    19501 gtggttttga caagttgtac aaacacagtt caagaaatca actaattatg gatttgccca
    19561 ttcgtttaaa gcgagtgggc ttacaattga accgtagacg atacaagtgt cgtgaatgcg
    19621 gatctacctt ctgggaacgc ctaatatctg tagatgaaaa gcgtagtatg accaaaaggc
    19681 ttttaaagtc cattcaagag caatccatgt ctaagacctt tgtagaagtc gcagaaagcg
    19741 ttggtgttga cgagaaaact attaggaacg tttttaagga ctatgtggca ctcaaagaac
    19801 gtgaatacca gtttgaaact cctaagtggc ttgggataga cgagatacat attatccgta
    19861 gacctcggct tgtattgact aatattgaac gcaggactat ttatgacatc aagccaaacc
    19921 gtaacaagga aacagtcatc caacgtcttt cagaaatcag tgacaggact tatattgagt
    19981 acgtcacaat ggatatgtgg aagccttaca aagacgcagt gaacactatc cttccacacg
    20041 ctaaagttgt cgtagataag tttcatgtag ttagaatggc taatcaagcc ttagataacg
    20101 tcagaaagtc tttgaaagcc catatgagcc aaaaagaaag acgtaccctt atgcgtgaaa
    20161 ggtttatcct tctaaagcgt aaacacgatc taaatgaacg tgaatcattc ctcttagata
    20221 cttggttagg taatcttcct gctttaaaag aagcctatga actcaaagaa gagttttact
    20281 ggatatggga tactcctgat ccagatgaag gtcgtctttg ttatagtcaa tggagacacc
    20341 gttgtatgtc cagtaactct aaagacgcat ataaagacct cgtgagagcc gtagacaact
    20401 ggcatgtcga aatattcaac tactttgata aaaggctcac taacgcttat acggagtcaa
    20461 ttaacagtat tattaggcag gtagagcgaa tgggtagagg ttactcgttt gatgccttac
    20521 gagccaaaat ccttttcaat gagaagctcc ataaaaagcg taagccacga tttaattcaa
    20581 gtgctttcaa taaagctatg ttatacgata ctttcaattg gtatgaagtg aatgatcacg
    20641 acattacaga caactttggt gtcgattttt ccacacttat taagaatttg gagaagggtg
    20701 atttataagc ccttttccac catgaaatcc gaatacccga aatatataaa tatcaagcag
    20761 aatctgaacg aaagaatata aaagaaagac aagcccaggg aataaagatt gctaaagacg
    20821 gtaaaaaata tagaggtaga aaacctttat ttacaaagga tagccctaga ttacagcatg
    20881 cttttgaatt atataagaat ggatattcag acaaagaggt tcaaaattta actggtatta
    20941 atcatgaaac atttagaaga tataggatta aacataatat tcaacgcaat atataaaata
    21001 acctcaccta attatactaa tgtgatcagg tgaggttatt ttttaaatct gtaaatttgt
    21061 aagagctggc attaactcat tttttagcca tatctgatta ggtacatcat ctaggaaaaa
    21121 gccttttgtt gttaaaatta agttatcgta ttcatctgtc atttttaatt cagcaaatgg
    21181 ggattgacta gcaatttctt tagcaatgct attcgtgtcg ctattaattt cttttacaaa
    21241 tttattatga ttatatacat gtaccttatt cattttattt attctccttt atggggtacc
    21301 gtcaggaaaa tgcggattta caacgttaag gaaatttatt aaagagacca attcctcagc
    21361 actaaaattg ataattgggc tttctttgtt actatagtgt taggtaagct ttttacttta
    21421 tcaccggttt tcccctcact tcacacctac gggcgagttt ccccacatcc cgttttccat
    21481 ctaatccaat tcattcaata tctttatgtg tatgaaagat cagattgctt gatttagaca
    21541 tcttacacgt aatttattct taaatgggta cggtaaacga gcaataatac gagcaaaagt
    21601 atacctacaa aaataataac tctgtctaat tttttttgat tcatatgctt attgcttaaa
    21661 ccatataatt tcagtccaag aaagcctcca acagtatttg taattacatc tgttatgtct
    21721 gtcgctccaa tagcgaagat aaattgaatt atttcaaaag taagacttaa aaccagtaca
    21781 aaagcaaact taggtaaaaa tccgatttct ttaaaattga cattcaaaag caagccaaat
    21841 ggaataaaga ttataacatt atctatcatc tctctgaaat tcccagtagc agtaaatgga
    21901 gtcaagttaa gacttctttg atgataatta aatactgata aaatattgta ttgtaatttg
    21961 aataacacta accagattag tgtcactaaa tataaagcta gcaatcctct agataatatt
    22021 tttcccaata taatttcctc taattctttt gtttaagttg tatcattagt atagcaatgt
    22081 cctagttaac gtgggtttta aattaaaaag ctaacgttac cccaaaagtg ctagtacaat
    22141 aatgctgttc attaatttcg ttggtttcat tccgccatcc ttacctcctt gaattagtat
    22201 gtgttgatcc gggaaacact gtcacaatta caccgtctat attgtttcct gatatctcat
    22261 aacgaagatt agtcggcaca tgaatggtgg tatttttagt aacaggataa taaaagatct
    22321 catatttttc cccatttaca ctaacagaaa tggttttttc ttcttttagg taatccatat
    22381 attcctcgag aacgaaattc ttttctttca taatcgcact atgtggtaaa ccaacatagc
    22441 gaatatgcca tggttcatat tgaattcctg ttaactctgt tttgtcctct ggataacgta
    22501 aaatgaaccc gtatttccaa gcattttctt ctatccactt tccttcaggg gctcgttcca
    22561 ttttcgtcaa gcttgatcct acatctagtg ataaacctga attatgctca ctataacctg
    22621 ctggtaaggc atactcagcc cccatttctt ggtaaagcac actttgctca tcaaagtctc
    22681 gatagccact attaataata aaatgactaa cgccaccctt tacagcatca ttgaccatct
    22741 ctgaaaattt ttgtgctatt tcttttgaca tataaatatt actatcaagc aacccgtatc
    22801 catttattaa ttcgtcatgt ttagataaat tcacgatatc tgacttcaca ctttcttggc
    22861 gaacaggata tttactattg attaatagca gatttccttg ataaacctgt tcttctgtaa
    22921 ttgttttctc ttgggtattt tcagaagtcc cactattttc taaatgttct ttgggatttt
    22981 gatcataatt ttgaaattcg actttttcct gagaaaacag tgcttcatta acgtagtcat
    23041 aacctaagta tattaagaat aacaataaca ataaaaaaaa acaacttctt cattttcagt
    23101 ctcctcctta actatatagt tggaagtatg aaatatttct agaatcttcc ccttaaacgg
    23161 cacaatctcg tttgagattg tgccgttttg ccccgtaaat tacagtcaat tatttcgccc
    23221 tactggattt actattatca ccaatgtaga tgaattttca taagtgatac ccatgctgaa
    23281 tttaacgagg ctgaactgcc tgttgacaat gggcggtgtg aaataccacc cctctatgcg
    23341 atcagtctta ttatcaggct atcttgccgc agcgcacgca gataatgacc gcaatatcgc
    23401 tctgccttac atcttcaata ctatctacta tatataaatt ccctaagaac cagttacata
    23461 cgtcgggttt cctgccgaaa gagttagctt atatagtttg tccgtgcaac ggttaaaagt
    23521 ttatttaacg gggaaatcaa aatagctatt ggggtatggt tcgtctctta atacatagtg
    23581 ccaccattcg aggctatatg cttcaaaccc actgttttcc atgatggagc gcaaacgtct
    23641 gcgattttgc gcttcattgc atgatattcc atttgccgca tgatgagagc gttcatccat
    23701 aaaatcaaat cggctcccca ttggtacaag ctcacccgtg tctaatcgat aaagcgtaag
    23761 atcaatggca ctgccgcggc tatggcttga ttttgaagcc acgtatcctt ttgaaatcat
    23821 ctcagttcgg tcaatattgg gataataact ttcctttgtc aggttatttt ccggctgtgc
    23881 agcccattgc ataaaacagt ttacagcacg cttaggacgg taaccgtccc atagaagcaa
    23941 tccgtaccct tgggtagcag ccagttcttt tgccttcaaa agcgattcag ccaactcgta
    24001 tgtccctaca atgcgattta cttcataacc gtcaaccggt tttccggtga aattatccca
    24061 agtggcatat ttagcgtccc aacgaacacc gtgtactatt tcatctaaaa aagtaaatcc
    24121 tatttccatg cttatcaccc ctttaacgct aatacgatca agcggtcaat cagttcggga
    24181 agtgcaatac ctgcagcggc catcatacgg ggataacgac tgtatgacgt gaaaccgggc
    24241 agagtattga cttcgttcag tacaatgcgg ccgttatctt gtaaaaacat atccacacgg
    24301 gctagacctc tacagccgag cgctttatat attttttttg ccgtttcctg tatccgtcct
    24361 cgctcctctg ctgaaaggtc tgcgggaacg gttataactg cgttttcaga gcctttttcc
    24421 ggctcgactt cctgatgaat acgaaagatt ccgtactgca gcctgatttg gtccacctcg
    24481 ccaacaacta acgcggcact gtttcccaat accgcacaac cgacctcaca gcccgaaaca
    24541 gcctgctcaa ttaagatttt gctgtcatat tgtcttgccg attcaattgc gtagtccaat
    24601 tcgtccgcgc tattgacttt tttcacaccg aaggatgagc ctgaacgcgc cggcttaaca
    24661 aaaacaggat aggtaaacgt agctgccacc ggcctatcat ctttattaat aacccaaaag
    24721 gcgggagtag ctatcccagc atttttcgca acgatgtatg tcaacgattt gtccatacaa
    24781 attgctgagc tttgaatatc gcagcctaca aaagggatac cggacaattc aaacagacct
    24841 tgtatggatc catcttcacc tgacttgcca tgcaaagctg aaaatgctac atcaacatgg
    24901 ttgatttcat attcatggtt ctttttaaca agtaatccgt gcattttttt atccggcgag
    24961 agtacagctg aatagcaatt gtcgttttcc cattccgcgc aaggtttttc gcacattttc
    25021 catacaccag atttcgtaat tccaatgtat aacggctcgt atttttcttt attaatgtta
    25081 gcggctatct ctattgcaga ttttaccgat acgtcatgct cctctgagca acccccaaac
    25141 agtattgcaa cttttattct attcatgctc ctgtctcctt tcaaaatcca aacagttttt
    25201 aatggttttt tcaacggtat cacgcaacgc ttgctcggta taataggccg tatgcggtgt
    25261 gattatcacg ttaggcattc tttgaagttt aagtaaaaat tgattatcaa ttggtttttg
    25321 ggtgcaatca gagtagaaaa actcttcctc tccttccaat acatccaatg cggcaccgcc
    25381 cagtttcccg ttttctaatg ctttaaccaa ctcataggta tctacaagtg gaccgcgccc
    25441 agtattgata agaaatgctc cttgcttcat tctctgtatt tgttcgtggc tgataatata
    25501 gtgcgtatcc gtattgagcg gcacatgaag cgtaacgata tcgctatttt gcagcaactc
    25561 atcaaacggt acatagttta cctctatact tcggctgcga ctataagcca acactttaca
    25621 tccaaatcct cgcagccgct caataaccgc tttgcctatc tggcccgttc ccaccacacc
    25681 aactgtcatg tcgctgagta ccttgccacg gtcgctgtcc aacctgaaat catgtttttc
    25741 cacagagcgc acaatcgatt ttacgttgcg tactgccata agaattagca tcatagtata
    25801 atcggcaacg ctatccggcg agtacgccac attgtcgaca gtgatgccca ttctcttagc
    25861 agcagttgta tctatatgat tgcagccgat gcttcgggta gaaatatatt tcacaccggc
    25921 tctcttcagc gcaagaagaa tagaggcgga aatctctgat ttatgtccca cactgataca
    25981 ttgattgaaa ggcgcggatt tggcgttgga ttccgacacg ttggcgttaa ttatcgttgc
    26041 cataacgcca aagcgaggcg aaagagcatg gaatgcatct gcctcatcct gctcacatcc
    26101 ataaacagta atgccgatgt tattcataat taagaccaac cctttctgtg aaaggcacca
    26161 aataaaacgg ggatgccaat ggtaatcttg tcaaatcttt ctctgaagaa cgaaaacggc
    26221 tcgttcttac ggtattaagt ctaccgtgta agaacgagcc gtttcttaat attaaattgt
    26281 taatttccta agaaaaagta aagataacct tgagattttc ctaaaaaatt atatacatct
    26341 cttaggacct ccttttatca accaagtctg gcatcgctgg aagctctacc ctaaacgtcg
    26401 tatagttatc attgctttcc gcgtaaatct gccctccatg ctgaacaata atttcttttg
    26461 caatcgccaa tccaagtccc gcgccacccg tatcggaaga acgagcattg tccagcctat
    26521 agaacttttc aaatatggca gctagcttat cttttgggat gcttccagtg ttcttgaatt
    26581 cgattgacac cacatccccg gagaggcccg cggtaatgtc aatgatgctg ttatcctcac
    26641 tgtatgcagc ggcgtttttc aaaatgttgt taaagactct cgcgagttta tcagggtcgc
    26701 cggacacggt cagatcctcg ggggcgtgaa taaccgcctg ttttccatgt gcggaaagct
    26761 gaggataaaa ttcatcggtc atctgcacca gcatatagta taggtctatg tgcgtttttg
    26821 ttagcgttat cgtttgtagg ttataccgtg taatctcaaa aaactcgtcg attagctgtt
    26881 cgagtcgata cgctttgtcc aacgtgatat gcacatactt tgccttttga tctaccggca
    26941 tgtctggagc ctcgtcaagc aggctcaaat aaccgataat ggatgtaagg ggcgttttaa
    27001 tatcgtgcgc caagtacata acaacgtcat tttttctttg ttcggccagc tttgcatcct
    27061 gctctcgctt ttccagagtc cgttttaatg tgttgagctt ttgttccata acatccattt
    27121 ccgcagaaag ctcaatttgt ttatcttcgt tctgaataag tacatcaatg ccggtattta
    27181 tctcgtcaaa gtattttgcg aattttgaaa gcatgacgcg acatagaata agaatactaa
    27241 tgacaatcgc cacataaata aagatatcta tattgttccg tatggaatat tgatataatt
    27301 tcatcgcgtc caggtgattt aagtcatatt tgttttccaa aatacttaag atccaatccc
    27361 caagtttccc tcggatcatt gaacgaatat acaacacgaa tacaattgct accacaacaa
    27421 ttgcaacgat atacatgtaa agttttcgtt ctagtttgga atagtcgttt tttttatttt
    27481 tcaattttat aaccaacccc ccataccgtt tttatatatt tcggattatc aatggtgtcg
    27541 ttcatttttt cgcgcaaatg ccggatatgc acggtgatgg tgttgttgct cttgctgaaa
    27601 tattcgtcgc cccatatctc atgaaatagc agctcggagc taaccacatt ccccttgttt
    27661 tcacagagga ttcgcagtat tgaaaactcg gtgggagtaa gggataactg cttctcgttc
    27721 agataacact catgggtgtt aacattaatg acaaggccgg agtggacgat aacattttcg
    27781 ttctgctcct ttactccact gaattttttg tatcggcgca actgggcctt tacccgagca
    27841 attaactcca gtgggcgaaa gggcttcgtt atataatcat ccgcgccgat tgttaaccct
    27901 gtaattttat ctacctctgt atctttcccg gtcagcatga taatcggata ggtgtgcttg
    27961 tcccttattt tttgacagat agtaaggccg cttgtgccgg gaagcatgat gtccaatatg
    28021 gcaaggtcaa tctcagactt gtctatacat tccaatgctt ctttggcggt atagtatttg
    28081 aaaaccgtat aattctcgtt ttttaagtat aattcaacca aatcggcaat ttcatgttca
    28141 tcatccacaa taagtatttt atcgctcata gttatcaccc tttcacataa gtttgccctt
    28201 aataatttat cagattatag ggccgaattt atacctgaat aattcatact ttttataaac
    28261 taccaaattt tataattatc tgtttagttt tatgctcaat ggttcttttt ctcaaaaata
    28321 tttttctaaa gggtttaatt tatttttgct aactgattaa gttcaagaaa gacctcattt
    28381 tgggcgcact catcctatcg gatggttaac gaattttttt gaatggcgca ataaacgcaa
    28441 ttaacactgc agtacctgaa tgttttgtag aatccgataa aatagcttct ggtaaacatg
    28501 gtaactactt aatttcaagt attgtcttct tccggaatga actatctttc cagcaatttt
    28561 aaagagaaat aagcgaatag tagaaacctg ataccctttc gtttcattgg taaaacacag
    28621 tgtccgcatg aagttcacga tattgtaagc caataggctt acgatcatac gagcatgatt
    28681 ttctataaaa cgtgggctat ctgttttatc caagtaaaag ccgttttttg cttccttaat
    28741 gtaattttcc atcgttcctc tttttgaata cgtttggaaa accatttctg gagagacgtc
    28801 ttttgaaaaa ttagtaatga tgaattcatg tctaaaaagc aattcactag cttctctggt
    28861 tgattttatg cagatccttc tggattttcc ccatgacttt gcttgataag tggcgttata
    28921 gtaatgaact tctttcttac tccaatcgtg atgatcctta atggtaatga attgatcagc
    28981 gattctgtac agattacgat tggatttcaa acggatagta tacaaactat cgtactcttc
    29041 acaaagctca tacaaatcag gcattgcgaa tccactatct gcacgtacca taatagtgct
    29101 tactggtgtc acagagtgat aatgctcaaa taatggacga gtaaatgctg cgacgccttt
    29161 tgaggtgtag acatttccag aacgaagttc tgctttaaga aagtctccgg taagaccatc
    29221 aaaggcaacg agtggatgat aaccggttgt ctggtaatgc gcattataat cggtcatttc
    29281 ttggtttcca aaggtatcac tgtgagtaga atctaaatcg aaaatcattt cgttcgtatt
    29341 tcgaatcgtc cgtgctttat caatcaaaat ctggttaacc ttttgtagct ggacgatatt
    29401 ttctgttgat atccgatccc aaaagcgaga aatggatgac tgtgaagcca accgcttttt
    29461 gcttaaaaca gcttgaaaga taggatccgt tgctaatata ttggctgaag aatctgtagg
    29521 atagcctgca atcaactgca agatgatttg ttccagaata gattcatttt catgaacatg
    29581 atacagtcgg tcatcttgaa tctggatgtt tttacataag atttggctaa actcaaattt
    29641 gttcatgaat tcttttgcta atattaagcc ggaatctgag gacaaatttc caccagagtg
    29701 agatactgta acatttgaat tgaaaagtag acgattttcg tgtaaagttg ccattgagag
    29761 aacccctttc tttggttagg tttagtcact ttaaccatag cagattgggg ttctttttgt
    29821 acacccaaag ggtgcgaata aacgaaacaa aatagactgt tataacaagg tttttgaaac
    29881 gtttttg
//
LOCUS       DAXLPY010000027        29877 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.027, whole genome shotgun sequence.
ACCESSION   DAXLPY010000027 DAXLPY010000000
VERSION     DAXLPY010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.027"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(85..495)
                     /locus_tag="ACF3UF_001348"
     CDS             complement(85..495)
                     /locus_tag="ACF3UF_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFD3671489.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(676..1110)
                     /locus_tag="ACF3UF_001349"
     CDS             complement(676..1110)
                     /locus_tag="ACF3UF_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3671490.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTDNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(1210..2058)
                     /locus_tag="ACF3UF_001350"
     CDS             complement(1210..2058)
                     /locus_tag="ACF3UF_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3671491.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            2447..4213
                     /locus_tag="ACF3UF_001351"
     CDS             2447..4213
                     /locus_tag="ACF3UF_001351"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFD3671492.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            4315..5574
                     /locus_tag="ACF3UF_001352"
     CDS             4315..5574
                     /locus_tag="ACF3UF_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3671493.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            5721..7022
                     /locus_tag="ACF3UF_001353"
     CDS             5721..7022
                     /locus_tag="ACF3UF_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671494.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            7025..7876
                     /locus_tag="ACF3UF_001354"
     CDS             7025..7876
                     /locus_tag="ACF3UF_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFD3671495.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            7889..8704
                     /locus_tag="ACF3UF_001355"
     CDS             7889..8704
                     /locus_tag="ACF3UF_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFD3671496.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            8855..10021
                     /locus_tag="ACF3UF_001356"
     CDS             8855..10021
                     /locus_tag="ACF3UF_001356"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3671497.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            10251..10898
                     /locus_tag="ACF3UF_001357"
     CDS             10251..10898
                     /locus_tag="ACF3UF_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFD3671498.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            10982..11926
                     /locus_tag="ACF3UF_001358"
     CDS             10982..11926
                     /locus_tag="ACF3UF_001358"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFD3671499.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            12061..13512
                     /locus_tag="ACF3UF_001359"
     CDS             12061..13512
                     /locus_tag="ACF3UF_001359"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFD3671500.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLIRSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            13533..14369
                     /locus_tag="ACF3UF_001360"
     CDS             13533..14369
                     /locus_tag="ACF3UF_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFD3671501.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            14369..15028
                     /locus_tag="ACF3UF_001361"
     CDS             14369..15028
                     /locus_tag="ACF3UF_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3671502.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            15154..15843
                     /locus_tag="ACF3UF_001362"
     CDS             15154..15843
                     /locus_tag="ACF3UF_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671503.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            15849..16805
                     /locus_tag="ACF3UF_001363"
     CDS             15849..16805
                     /locus_tag="ACF3UF_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFD3671504.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            16849..17361
                     /locus_tag="ACF3UF_001364"
     CDS             16849..17361
                     /locus_tag="ACF3UF_001364"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3671505.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(17617..18165)
                     /locus_tag="ACF3UF_001365"
     CDS             complement(17617..18165)
                     /locus_tag="ACF3UF_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFD3671506.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(18254..19435)
                     /locus_tag="ACF3UF_001366"
     CDS             complement(18254..19435)
                     /locus_tag="ACF3UF_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFD3671507.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(19671..21179)
                     /locus_tag="ACF3UF_001367"
     CDS             complement(19671..21179)
                     /locus_tag="ACF3UF_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFD3671508.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            21338..21529
                     /locus_tag="ACF3UF_001368"
     CDS             21338..21529
                     /locus_tag="ACF3UF_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671509.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            21732..22649
                     /locus_tag="ACF3UF_001369"
     CDS             21732..22649
                     /locus_tag="ACF3UF_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFD3671510.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            22642..23715
                     /locus_tag="ACF3UF_001370"
     CDS             22642..23715
                     /locus_tag="ACF3UF_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671511.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            23863..24381
                     /locus_tag="ACF3UF_001371"
     CDS             23863..24381
                     /locus_tag="ACF3UF_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671512.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            24362..24754
                     /locus_tag="ACF3UF_001372"
     CDS             24362..24754
                     /locus_tag="ACF3UF_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFD3671513.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            24830..25765
                     /locus_tag="ACF3UF_001373"
     CDS             24830..25765
                     /locus_tag="ACF3UF_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFD3671514.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            25898..26677
                     /locus_tag="ACF3UF_001374"
     CDS             25898..26677
                     /locus_tag="ACF3UF_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFD3671515.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVFFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            26670..26987
                     /locus_tag="ACF3UF_001375"
     CDS             26670..26987
                     /locus_tag="ACF3UF_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFD3671516.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            27231..28841
                     /locus_tag="ACF3UF_001376"
     CDS             27231..28841
                     /locus_tag="ACF3UF_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3671517.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            28998..29846
                     /locus_tag="ACF3UF_001377"
     CDS             28998..29846
                     /locus_tag="ACF3UF_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3671518.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT         9706 a         5325 c         5886 g         8960 t
ORIGIN      
        1 cttgattaac taaatataga tcttccattt ttccacctcc gctgttttac tatagtgtat
       61 catagcggat ttacacaaaa aagtctattc actaactgct ttcagagtaa cttctatatt
      121 tccagctgta gcttttgaat acggacacac tttatgcgct gcctctaata attcttgcgt
      181 ttcttccaga gaaagacctt cgatagatcc ttcaatctct acacctaaga caaagctcgt
      241 ttcactttct gaataaaggg aaacttgtgc actgacagta gaagccccag agatattttt
      301 ttgctgtttg atcaattcta atgcactgtt aaaacatgca ctgaaaccag ctgcaaacaa
      361 ttgttcaggg ttggttgcat tttcgacgcg tttaccagga gctgcaatat tcaattcgaa
      421 tgtacgatcg ggattatgaa cttctccaga gcgtccgcct gtgttgatca ttttcgtaga
      481 atacattttt ttcataaaat taccaccttt aattatattt tatacaattg aattttacac
      541 aatataattg tggaaagcaa agaaatggat tggcataaga taaataagag aaagcacatg
      601 aaacagacgc gctttctcga atagcaaaca tatacaaaaa aatatcagag acaaaaacta
      661 atctcatcat aaacattaca tatatttctc aaaaagttgt tttctttctt caaaacttac
      721 ttcacgatgg acctgatgaa gcatccataa ataaccaaaa ggatctctga acattgagtt
      781 agtcacacca aagtccatca tttctgtcat ttcttgaatc tctacacagc catttcgtaa
      841 tgctttatta tctgtgtcct cgatatcaga gacgatgata ttgaaccaga tcgtatttgg
      901 atgttcagca gtaggagcag tcaaaccaag agacgtgttt tcatccagca tatggaatct
      961 cgtgccatac aaggtaaaaa tgacttcatt attgcctcta gggtaatctg ttgcctcaat
     1021 cagttgtatt tcatcaaaga ttgtttgata cagttctagt gctttcaaac tatcatttaa
     1081 tacaaaatct atttccgttc ctttatgcat aaagatctcc tctccttttc agtcgaacag
     1141 ttactagatt cttttattat accagttaaa gaaaacgcat tcaaaaaaat agcggattta
     1201 cttaccaact cattcgattg gatgataagt aaatccgcgt cccattactt ctgctacgct
     1261 gctgacaatg acaaaggcac ttggatcgat ttcttctatc aatggtttca ttcgggaaaa
     1321 ttcatgatca gtcacaacga tcaataaaac ctcttttgac tttcgattat acccgccttt
     1381 tgcctctagc agggtaaggc cacgtccaat ctcagcactt aagcgaaggc ggatgtcttc
     1441 caaataatgt tcactcatga ccataacaga tttctttcga ttgatacctg tttcgatata
     1501 agtcatgaca attgaagtga ttgcaataga taaaatagca taaagaaact cttctattcc
     1561 aaaaacaaac agattaagag aaacaacgaa tgcgtctgta aaaaataagc caatcgaagt
     1621 attcaagtgg aaatattttt taaaaatgag gggagggatc gtcgtaccgc cgctagaaga
     1681 gttgttttta tataaaatcg caactcctaa agcaaaaatc gcacttccaa aaatgacaga
     1741 caacaaccga tctgaagtaa tcattgtttc tggaactatt gcaatgatta aaggaaaaaa
     1801 caagcttccg aaaagtactt taaaaaaggg ttttttacct aaaaatagaa gagctagtac
     1861 caacataacg atattcaaca ctaaaataac tatagctcgg tcaaatccta aaacagcttc
     1921 cagtaatatt cctagaccgc tgacacctcc agcagcaata tgatgaggcc ctaaaaacat
     1981 attgatagcg actcctaata tgaagagggc aaaaataatc ttaatgtatg tccatataaa
     2041 ttgtctcgtt tctttcattt atccacttcc ttaattcatt aataatactc ttatcttatt
     2101 ataacttact tttcacctta agttaacttt aattaataaa aaaattaggc tagtctaaat
     2161 tattatgttt cattcttcta gaatatactt ctacgttaaa aactgttaaa aaacttttac
     2221 tttagaaaat tggagaaatt gatcgcttaa gataaattca ggacactaaa tagtacagga
     2281 agtagattaa aacttttaaa agttttaagt ctatctattt ggcaagttta aaaaataaaa
     2341 attcggtatc aaaaaactgt taccgataac atttttgaaa gcgttgtctt ttgtttctct
     2401 atcacttata gtgatgacgt catattaaaa cacaaggagg aaatcaatgg atacagctgc
     2461 aatttatcat cgaccggaaa gtgaatatgc atttctatat acgaatacaa gatttcgtat
     2521 tcggcttcgt actaggaaaa atgatatcaa aaaagtatat gtgctttgtg gagatccata
     2581 taccataaca actgaaaaat ggtatcaaaa acaacgacca atgaaaaaat gtctaagtac
     2641 caatgttcat gattattggg aaattgaagt gacgagcgaa acaaggcgct tacagtatgc
     2701 gttccatgtt gttggggaag ataacacgga ctgtttttac ggtgatcaag gaatttttcc
     2761 ttatcgagaa aatgtgatta ctgaaccaaa tttttatttt cgaatacctt attttcatca
     2821 aatcgatcga ttcactattc cagaatgggt aaaagaaaca gtatggtatc aaatttttcc
     2881 cgaaagattt gcaaacgggg acaaagcaaa tgaccccgaa cacactttac cttggggaag
     2941 taaagatcca gaccgagaag acttcttcgg gggagatttg caaggtgtga gggatcattt
     3001 ggattacttg acggaccttg gcgtcaatgg catctatttt tgtcccatat ttaaagccac
     3061 atccaatcat aaatacgata cgattgatta ttatgaggtg gatcccgctt ttggcgataa
     3121 aaaactttta aaaaacttga ttgatgaagc acataaaaga gggatacgta tcatgttcga
     3181 tgctgtattc aatcatatgg gtgtccattc accacagtgg caagacgttc tcaaaaacgg
     3241 agaaaaatcg atctataaag actggttcca catccgtttt ttcccagtag attcttatca
     3301 gatgactgac ttaccagaaa ctgctgaaaa tatcccatat gatacttttg cttttactcc
     3361 attcatgccg aaactaaata cagcaaatcc agaagtgcaa aaatatttgc tggatatcgc
     3421 aacttattgg ataaaagaat tcgatattga tggatggcgt cttgatgttg ctaatgaagt
     3481 cgatcatcat ttttggaaaa aattcagaga agcagttaca gaaatcaaac cagacatcta
     3541 tatccttgga gagatttggc attcctctca agcttggctg caaggggatg aattccatgc
     3601 agtgatgaat tatgcattca cagattcgat taaagattat tttgcaaaaa agaaaatcac
     3661 agcttcacaa atggtcagtg gaatgaatca tcagcaaatg ctttacagag atcaggtgaa
     3721 cgaaggaaca ttcaacttat tagattctca tgatactgcc aggatcttga ccctttgcca
     3781 aggtaacaaa gaattgatga agtctgtgat ggcctttatg tttcttcaaa aagggtctcc
     3841 ttgtatctat tacgggacag aaatagggat gactggtgaa gatgacccgg attgccgcaa
     3901 atgtatgata tgggagaagg aggaacaaga tctagagcta ttcggtttta taaaagaact
     3961 tgtttctcta aggaaacagt tgtctaagat tatttctgaa ggttctactc agtggctaat
     4021 agtatatgat cgtgaagata agctctattt cacacgggaa ctagagggac agatcatcta
     4081 tgtttacttt aatcagtcaa aagaaccttg ggtagtagaa caggaaaatg aggtgattct
     4141 tagtcaaaat tgtcagttgt tagaagacgg gaaagcagag atacgacaat acggattttt
     4201 gatcatgtgt tgaaaactgt taccggtaac aacaagaaag cgtttgcaaa tgaagatttg
     4261 tgcccattat aataagggtg taacagcacg ttgaatacac aggaggaaat gaagatgaaa
     4321 aaaagaagtg tgaaacagtt gggtttaggg ttaatctctt taggaatctt aggcggatta
     4381 gcggcttgtg gcaatggtaa ctcttcagca gaaggggaag ccgatgaagg aaaaacgtta
     4441 acagtttccg ttgattctgg atataaagat tatataaacg aaataaaaaa cactttcgaa
     4501 aaagaaaacg atgtgaaaat caagctagta gaaaaggaca tgttcgatca gttggaatca
     4561 ttagcgttag atgggcctgc tggaaaggga cctgacgtta tgatggcagc atatgaccgg
     4621 atcggtgcgt taggacagca aggacatctg gcggaagtaa aactgggaaa tgaagcagct
     4681 tacgatgaaa cagacaaagc ccaagtgact tatgatggaa aaatctacgg agaacctgca
     4741 gtaatcgaga cccttgtttt gtactataac aaagatttag tcgatacagc accatcaacg
     4801 tttaaagatt tggagaatct atccaaagac agtcgttttg cttttgagtc agaagcagga
     4861 aaaaatacag gatttttagc taaatggact gacttttatt attcctatgg tttaattgca
     4921 ggttacggtg gctatgtatt tggtgatgat ggcacaaatc cttcagatat cggtttgaat
     4981 aatgcaggtg ctgtagaagg aatctcttat gcaacagatt ggttcaaaaa tgtttggcca
     5041 aagggaatgc aagacataaa aagtgcagga gacttcgcca gccagcaatt catgtccaat
     5101 aaaactgcag caatcattga cggtccatgg caagcgcaaa catacaaaga aaacaatatc
     5161 aattatggtg tagccaaaat tcctactcta aataatggac agccttatca accgtttggc
     5221 ggaggaaaag gatgggtagt cagcaattat gctaaaaaca aagacctctc tcaaaaatgg
     5281 cttgattatg taacgaatca ggaaaatcaa gaaaaattct ttgaaatggt aaatgaaatc
     5341 cctgcaaacc aacaagctag ggaaacagca aaggctaaaa acgatgaatt aacaacagct
     5401 gtgattgaac aatatgaaac agctcaagcg atgccaaaca tcccagaaat gggcgaagtt
     5461 tggacaggtg cagaaaactt gatgttcgat gcagcatcag gttcaaaaac accaaaagaa
     5521 tccgcagatg aagcagtaaa aacaatcagt gaagccatag aacaaaaata ctgattaaaa
     5581 tgataaccgt ccatttttat aaaaaatgga acaggtgctt cagataaaag tggcaagagc
     5641 gagatggaaa attatcttgc tcttgttgcc attatcttaa aagcagtttg cggtttagca
     5701 agtttagagg gggcattcag atgcagcaag ataaaacaag caatatcaac gaaaaaaaaa
     5761 tcacgctttg ttcacttatt ccagggatgg ggcagtttgt aaatggccaa gcttttaaag
     5821 gtatcgtttt tttcgccata ttcgtcctat tcattggtca gatgcttctg ggcggatttc
     5881 atgcattggt aggattggtt actttgggaa gtataccaat ggaagatcat tcattattta
     5941 ttttgattga aggcactttg caattcatca ttacaatcat tttcttgatt ttttacggtt
     6001 tgaatctttt agacgcttat cgagtagcga agatgcgtca agagggcaaa aaaatcaatc
     6061 ggacgatgaa ggaagtcata cataatatag gtgatgaagg ttttccttat ctattgacac
     6121 ttcccgctta tcttctcatg atttttacga tcattttccc agtcctagtt acattgttca
     6181 ctgcatttac taattatgac ttcaatcata ttccaccagc cagtttaatt gattgggtag
     6241 gggctaaaaa cttttttagt atcttctttt taagctcata tcgtaatact ttttttgcag
     6301 tcttttcgtg gaccgtgatt tggactttat gtgcaacaac tttgcaaatc acccttggta
     6361 ttctcacagc ggttgttgct caccagaaat ttattaaatt caaacgtatt ttcggtatca
     6421 ttttcttatt accatgggcg gtcccagctt ttattactat catgagtttt tcgaatatat
     6481 tcaacgatag cgtaggtgcc atcaatactc aagtgattcc tttcataaac cagcttcctt
     6541 ttgtagatat cagtgcaatc tcttggaaaa cggacccgaa ctggacgaaa gtagcaatta
     6601 tcttagtgca gggctggtta ggatttccct atatctatgt gatggttaca ggaatcttac
     6661 aatcgatttc agaagactta tatgaagcag caaaaatcga cggagcaaat gcatggcagc
     6721 gcttttcaaa catcacgctt cctgctgtct tcctagtggc agcgccaaca tttattacac
     6781 agtatacggg gaatttcaat aatttctcca tgatctatct gtttaacaat ggtggtcccg
     6841 gaagcgtagg cggaggagct ggttctactg atattcttat ttcctggatc tataaactta
     6901 cgactggaac ttctccgcag tattctatgg cttcagcaat cacgttgatt atctccgtca
     6961 tcgttatctg tgtgtcattg ctggtattta aaaagacaaa tgcgttcaat atgggggatt
     7021 aacaatgaaa aaatttcatt cgagtgctcg attccaaaaa cgactttctc acttttttac
     7081 ttactttttt cttttaatac tgtcagtcat tatcatctat ccgcttttga tcacagcaag
     7141 tactgccttc aagtcaggaa atattgcagc ttttagttta gatctttcaa gtgactggac
     7201 tttaggaaac tttactcggc tattcagtga aacactttac gggacttggt ataaaaatac
     7261 attgatcatt tctgtcctaa caatgatcgt acaagtgact gtagtaactt tggcgggcta
     7321 tacttatagt cgctatcgtt ttatcggccg caaatcaagt ttgatgttct ttttagtgat
     7381 tcagatggta ccgactatgg cagcattgac tgccttttat gtcatggctt tcttattaga
     7441 agcgctcgat aagtactggt tcttgacaat gatctatata ggcggtggaa ttccaatgaa
     7501 tacttggctg atgaaaggat actttgacac tgtaccaata gatttagatg aatctgctaa
     7561 acttgatggg gcagggcatt tcaggatttt tttccagatt gtattaccgc ttgtcaaacc
     7621 gatgctcgcc gttcaagcat tatgggcttt tatgggacct tttggggatt tcatgttagc
     7681 taagttcctg cttcgaacac ctgaaaatca gactgttgct gtcggcttac aaacatttat
     7741 ttctgatgtg acaaaccaaa gagtctctct ttttgctgct ggggcaattt tgattgcact
     7801 accgatttgt ctattattct tctttttaca aaagaacttt gttaccggcc tgacatctgg
     7861 cggaacaaaa ggataggagc agagtatcat gcaaacattt ccgttaaact atttttccgc
     7921 attacgtacg ccaactcaag tgtttgcggg acgcaaacta ttatcatggc ctaaattttt
     7981 cttgatattt gtatttttag tttccttgat ggtcatgcct gtgactcttt tttatgccaa
     8041 tcagatccaa gcgattccat tagaacaatt tctatccgtt cattcgctga tcgatgaaca
     8101 aggaacccaa aaattttctg aacttgaatt atctgaaact gggttacaag catcgcaaca
     8161 aacgatagct gtgacccctg aaattttggt aggtgtgtct ttatctgaga aacaacaatc
     8221 cgatcatgga acttttattg attttgagaa ggaacaatgg gtgatccaac aaaaggataa
     8281 atctggtata cgccgctata cgatgaatta tagcccatct ttccaaccag attctgtacg
     8341 tacgcccgaa gatttccaac gatttttaga aagagaattt tatgccagta atcgtccaac
     8401 aatcatttta tcttatagtt taagtcttgg tcttgtccta tttgtcatga cgagtctcat
     8461 tttattcggg gcttcctttt tcttgtggat gacaagaaaa agccaacttt catccattca
     8521 tacattcaaa gagagtgcaa atttgatgct gaatgttatg ggaataggtt ccatggcagc
     8581 agcagttgta gggtttatcc actttgactt tatcttgatg ctaagtgtcc aaacaacgat
     8641 aactgtcttg ctgcttttat gggtttttgt caaaacaaga ttcaaagata agcgtgtcga
     8701 atgacaagtt taagcgattt atgcgacaat gaatgtgaaa aaaatgaaaa ataaagtagt
     8761 ttttgaaaaa tttctgaaaa aattaaactt cttagttgat tcttttcttt tttagtatta
     8821 acgtaatagg gtagtttttt taaggaggaa aatcatgtta gagaaaactt tatacaatca
     8881 attattttca cgttctttct cgctccctgt cgaagtaaat tattgggacg gtacaacgaa
     8941 acaatacgga gatacggaca ctcctcccca aatcaaaatc aatatccatg aagaaatccc
     9001 aatgaaagag attacaagta acgcttcttt ggcactagga gaagcctata tggatcatcg
     9061 aatcgagatc gagggaagta tccaagcatt gatcaacgat gcttatcagc aagcaaacag
     9121 ctttttacga ggaaaagatt atctaaaatg gctgccaaag aaagaaaaac atacgaaaca
     9181 aaaaaacaaa gaagatatcc atgcgcatta tgacttaggt aacgactttt ataaactttg
     9241 gctagatcca actttgactt attcttgtgc ttatttcaat acacctgaag atacgttgga
     9301 acaagcacaa atcaataaag tccatcatat cttagacaaa ctctttatca aagaaggcga
     9361 aacgttgctt gatatcggtt gtggctgggg aacattgatg ttcactgcta ccaaagagta
     9421 taatgtcaag gcaactggga tcacactaag tgaagaacaa tacgatttga ttaccaaaag
     9481 aataaaagaa gaacatttag aagataaatg ccgtgtatta ttaatggatt accgcgaact
     9541 aaaaggcgaa acgtttgatc atatcacaag tgtaggtatg ttcgaacatg taggttctga
     9601 aaatcttgaa ggttatttca aagtggtaaa agatttattg aaaccaaaag gaacagcttt
     9661 gatccatgga atcagccgac aacaaggcgg tgcgacaaat gcttggatca ataaatatat
     9721 tttccctggc ggttatgtcc ctggtgttac tgaattagtt gataatatta caaaaaacga
     9781 tttgcaactg attgatttgg aaagcttacg tcgtgactac caattgacat tagaacattg
     9841 gacaaagaat tttcatcaag tccaagatca agtcacgaaa gaaatgggtg attccttcta
     9901 tcgaatgtgg gatctatatt tacaagcttg tgcagcttca tttgaatcaa gtaatatcga
     9961 tgtgattcaa tatttgcttg ttcaacctgg aaacaatgac atcccaatgc atcgtgcata
    10021 attgaggcaa aagtactgtt taaagactat ttaaaaagaa gctaagtttt atgatgctcc
    10081 agaagtgaac ttttttgtct aacttctagg attgtctcta aagcttagtt tctttttctt
    10141 tatattttca taataaaagt ttggttcttt aatttttaaa catgacagaa aattttttct
    10201 tcgttatact tgtaatagaa tactatttta taacaaaggg gatcgaatca atgaaaaaaa
    10261 ctgttattta tactagttta tttgcagctt tgtttttagc tgcttgtcaa tcaaatacca
    10321 atcaaggcac atctgggaat acgtcttcca gtagcgaaca gcgctcttca caggtatcgg
    10381 actcctcaac aaaagcaagc acatcttcgt ctagccagac aaaaagttct agtgaagcaa
    10441 gtactcagtc agatatcaaa gtgtctgcag ctcgtgcgat cgaattgttc caagataaat
    10501 acccagatac tgcaattact agtttggaat tagatagtga ttggggatct tacttctaca
    10561 agatagaagg tgtcgatgat caaaaagaat acgaagcaag aattgatgct caaaatgaaa
    10621 aaatggagac agagaatcca gaaactctag atcgagatga acaaaatggt caaaagaaaa
    10681 aagaagatgg tctggatgtt gataaattga tcacgattga ggaagcagca aaaatcgccg
    10741 tcgacaaagt aggaagcggt acggcaacag attgggattt ggataaagat ttaggtacta
    10801 cttattggga agtcaaagta aaagacggca atcaaagtac atcagtcaag atcaatagcc
    10861 aaacaggcga agtactgtca actgaacaag atgattaaga atttcttcgg aaaacaagag
    10921 ttgatttttc ttttagtcat gatacactag acaaaataac ttgtttgaag gagcgattta
    10981 cttgagttta gaaacgacct ttgccaatca tatctttgcc aatcctttga tgaatgcatc
    11041 tggtgtccac tgcatgacta cccaggaatt agatgaactg gctcattcag aagcaggagc
    11101 atttatcact aagagctgta cgatcaatga acgaaaagga aatcccgaac cacgctattt
    11161 tgatgttcct ttagggagta tcaattctat gggacttcca aacttaggtt tttcttatta
    11221 tctagagtat gctcttgcgt atgaaaaagt gcaggaaaac caaaatcaac cgttattttt
    11281 ttccattgcc gggatgagtg tccaggaaaa cttggaaatg cttgagaaaa tagaaaaaag
    11341 tgggtttaat gggatcactg aattaaattt atcttgtccc aatgtgcctg gaaaaccaca
    11401 actagcttac gattttgagg ccacttatga aacactgaaa gaagtattca gcatcttttc
    11461 taagccgcta ggaatcaaat tgcctcctta ttttgatttt gctcattttg atcagatggc
    11521 tgatatcttg aatcagtttc cattgaccta tgtcaatgct atcaacagtg tgggcaatgg
    11581 tttgtatatc gatacagaac aagaagcagt agtcatcaaa ccaaaagaag ggttcggcgg
    11641 cattggcgga gagtatatca agccgactgc tttggcgaat gttcgcgctt tttatacacg
    11701 tttgaaacca gaaatccaaa tcattggtac aggtgggatt cggacaggac aagatgcatt
    11761 tgaacatctg ctatgtggcg caagcatgtt acagattggt acagagcttc ataaagaagg
    11821 gccggaaatt ttttctagaa tcataaaaga attaacgcag attatgtcag aaaaaggata
    11881 tacgtcaatt gacgaattta aaggcaaatt acgcaccatt tcatagcaaa gagacgaagg
    11941 tcatgattga tcttcgtctt tttttataaa aaacactcgt ctgttcattc ctgtgcaagc
    12001 gtactcattg tatgttagac gaacttgtgg gaaaataaca gaggcaaaaa ggaggataat
    12061 atgaatgatg caacagaatt agcaaaagag cttaaagaaa aagaatttag ttttcaagaa
    12121 ctagttacgg atatacagaa aaaaataaag aagcaaaatc atgaattgaa tgcgtttgtc
    12181 gcgcttgaac cattcgagag taattcccac gagctattga ttccccagtc agaaaaaggg
    12241 ccattggctg gtatcccatt tcctttaaaa atgctcggtc aagaaaaaaa gggatggcta
    12301 gctacttcag gatctcgttt atttgaaaca caccgagctt ctcatacatc taattatgtg
    12361 cggcaagcag aagcgatagg tctagttcct tttggacaaa ccaatgcgcc agagtttggt
    12421 ttcaaaaata ttacagaccc agtcatctat ggcccagcaa gaaacccttg gaaccttgaa
    12481 tgtacaccgg gcggatcaag tggaggagct gctgctgcag tttcatcagg aatcgttcct
    12541 ttagctggtg ctagtgatgg cggtggttct attagaatac ccgcttcgtt ttgcggattg
    12601 attgggctga aaccttcgcg agggacgatg ccagttggtc catatgcttg gagaggatgg
    12661 caaggagctg ctattgattt cggcttgaca gtttctatga gagacacgga ggctttattt
    12721 tatgggatga gaagtatcca ttccggtgcg ccatatcaag tatcgccagt tgagtggcaa
    12781 acacatccaa gaaaaaaacg gttgaagata gctttttgtg ttgattcacc gatccactca
    12841 cagattagtg aagaggcagt acttgctgta aaaaaagctg tagatttcct tggaaaagaa
    12901 gggcatgatt tgacagagat tccttaccca ctagatggtc gtaaactgat caggtcttat
    12961 tatcagatga atggcgcaga aacagcagca atgatccgct cgattgaaac aggcatccag
    13021 cgagctgtca gaaaagaaga acttgaaccc atttcttgga ctttgttcca atatggtcag
    13081 aagctctctg ccgctactta catcgattct ctgcatgtat gggatgaagc agcaattgtc
    13141 atggaaaacc tacatcaaga atacgatcta ttcctttcac caacgactgc atttaccgcc
    13201 cctaaaatca gcgaagattt gcaaagtgat gcgataagag cacagatgga acacatcagt
    13261 gattgttctg aagtagaagg tttagacgtt gtttcttcca tgtttgagga gagcttgaag
    13321 atcacacctt atacacagtt ggctaatctg actggacaac cagcaatcag cttgcctact
    13381 catttgacaa aagaaaacat gcctctagga atccaattta tggctgccag aggaagagaa
    13441 gatttgctat ttcaaatcgg ctatctattt gaagcaaatc atcagttcca tttaccaaat
    13501 ccatggaaat agcagaaaca aggagaagaa gaatgaagaa aaaaagattg tttgctctaa
    13561 taactagtgc cttttttatt ttaagcgctt gcggtacagc tgccgctaat caggaagata
    13621 acagctggag taatgtagaa aaaaagaaag aattagtagt agcgacttct ggcacactgt
    13681 ttcccgcatc ttattataat gatcaaaatg aattagttgg ttatgatgta gatttggcaa
    13741 aagaggtggc taaacggtta aatgtcaaaa tctcctttaa agaatacaac gtggatggac
    13801 aaatcacttc tgtttcaaaa agagaatcag attttgctgc gaacgatttt ggtatcacaa
    13861 aagaaagaga aaaaaaattc tccctttcag agactttcaa atattcattt gacagtatga
    13921 tcgtacgaaa aaaagatgat tcaggaatcc actcacttga agatcttaaa gggaaaaaag
    13981 cagctggcga acccaatact agctatatgc gtttagcgga aaaacacgga gctaaattag
    14041 tcacatatga caatgccacg aatgatcagt atttaagcga tgtagcaaat ggtcgaacag
    14101 atgttattct aaatgattat tatctgcaga aaatggccgt atctgcttta ccagatatcc
    14161 ctgtaaaaat actggagaac gtttatttca atgaaaacga aagtggtttt ttattgaaag
    14221 aaggaaatga tgctctgaaa aagaaaatcg atggcgtatt aaaagagatg aaagaagatg
    14281 ggacgacaaa gaaaatatct gaaaaatatt ttcaaactga tgtttcagtc aaaccgaaag
    14341 aaacgatggc tgagtcggtg agtgagtgat gtactttcct ctaattgatt tttccctcat
    14401 gtggacttca cttcctttcg tactgcaagg cttggtatac acattaggga ttggcttcgt
    14461 gtcgtttctt ttaggaaatt tggtagggtt gcttttgaca gttttaggtc ttttggattg
    14521 gctgcctctg aatgtattta ttcgttttta tttatcgttc tttagaggca ttcccgcact
    14581 agtcctgctg tttctgttat atttcgggtt accttatcaa ttaagtgcct taacggcttc
    14641 agtcatctgc tttacgatta ccagcagtgc atttattggt gaaatctatc gaggatcact
    14701 agcaggcgtt tcttcaggtc agtgggacgc tggtttagct tctggttttt ctttctttgg
    14761 ggtattgaaa tatatcgttt tgccgcaagc ttttcgaatc tcagtaccgg cactcagtaa
    14821 cgtagctatg gatctagtga aaggtacttc gttagcagca acaatcacag tgccagaaat
    14881 atttcaaaaa gcaaagatca taggcggtcg gacattcgat tatttttctc tctatatttt
    14941 agttgcactg atttattggg tcatttgtat cgggatcgaa aaagtgcaac agtatttaga
    15001 aaaacgttct atccatcagt caatctgaaa aatagaaatg gtgctagcgt ggctggcacc
    15061 atttctattt tttgtttctt gtatattctg cctagtattt taaaaccatt tcatgtaaaa
    15121 tgtaaatcga aaatatgttc ggaggtagaa aacatgaaga ccccgctaac catcgaaata
    15181 gaatcctcgt tataccaata ttgcatcgag caaggcggct tggttgtaga agaagtcacg
    15241 atgcctgatg accaaggaat tgtagatacg cttagctgct tgacaaaatt tgatggaagc
    15301 cgagaatggc gatgctatga gctgaaagtg acaaaagcag attttcgctc tacagccaaa
    15361 ctgtcatttg ttggacatta taattatttt gttttaccaa gtaaactata tgaagaagta
    15421 aaaactgaaa tccctacagg aataggtgtt ttagtgtatc gtccgtacac ggttgaagag
    15481 gagatgcctg cctctggtac atttctgatt gcgaaaaaag cagcaaagaa agagcttgct
    15541 gtaccggaag aagctttgac aaaccgcttc atggcttctt tattcaggga agtaagaaaa
    15601 gcaaagcaaa tggagcgagg cgtaaaatat tttccaaaag atcaattgta caaagaattg
    15661 aaaagacgtt cagaaaatca agatccattt tctaacgaac gatattatga acggttttta
    15721 gaggaaatag ctagtcaggc aatcaatgag ttgcaagaag aagttatcgc gcttcagcat
    15781 gattatgaat atttgaggca acaacagcag atccgtcggt tgcctacaga gccattggag
    15841 tgaaaaatat gtactatcct tatttaagag gaaaacaatt tgacctatta gcattaaaag
    15901 aagcactgtc gcgaggattg ctctccaata aaatccaacc agtgatcgaa ccagtacgtg
    15961 attccgctac gcttaaaaat gtgatcgaat tatttcaaaa aaagcaccat ccaatcgctg
    16021 tgatccaaaa tccccaagta ggacaattca aattattcga tcagcatgtg cacagttgga
    16081 cagtcaaaga aaatagctct gtcgtccctg cacagatctt aacgccagaa aatctcagtg
    16141 aagtactgga ttcacctcca gcgtttcttg ttttcgatgg acagcactac ccaaaagata
    16201 cagaggtgtg gaaacagttg gcaggagttg attcgaaatt tttgatacca gatactagtc
    16261 gctttcgcat ctggctgccc gaaaacaaaa ttgtgatccg tgactctttt caaacgagaa
    16321 agcatgttga aagttatgca gataaaacag atgacttttt tagtgatgac tatctttttt
    16381 tccacgcaga cggatatatt ggattttctg atttcacgat cgaaggtagc cgttatttcg
    16441 ataaagggtt ccctagccga gcgcttgcta tccatctaac gtatattgat gcttacggca
    16501 atatacgcgt gaaacatttt gtctctgaca gtaacgactc tgctaaagac caagcattga
    16561 agtttcttga agcaggagat aaaatgaaaa aatggatcat gcgtcaccat catcaactct
    16621 tgattacttc aggaatgatt gaattattgg ctctttacca gcaacaaaaa ttccctggac
    16681 tgggagtgtt gaaaaagtgg tcacttatgc atcatttgga acttattagt cacctgctag
    16741 atcatccaaa agattggctt aaatattatt caaaagttca ggaactatat gaagtgatcc
    16801 aatgattaga taatgtaaat gaaaaaggaa tagaaaagag gaaactggat gtatattcgg
    16861 caaacaagga aagaagaagt agaagaagtg gtagaaatca ttaatgccgc agcggatttc
    16921 attgcttcgc aaggctctcc tcaatggcaa aacgggcaga aaccaacaaa agaaacgatt
    16981 ttgaacgata ttgaaagaaa agaaagctat gtattaatag tggaagatca aattgctgga
    17041 acagctgcat tagtctcagg cgtggatccc gtttacacaa aaatagatgg tagttggaaa
    17101 gaatcaactg gtccttattt atcgattcat cgtgtcgctt tagcagaaag tactcgagga
    17161 aaaaaactag caaaaccgtt cttagaacat ttgttgacga ttgcagccag caaaaatatc
    17221 caagatatcc gtatcgatac ttatccagct aatgaaccga tggaaaagac catctattct
    17281 gctggattca cttatcaagg gatgattgaa tttccttttg aacacggcga aagaaaagca
    17341 tatcaaataa tcatcaattg actataaaat catctgagca aagataaaga cattaacact
    17401 actgaaaaaa acaatcatat gatagccaag aggttgtaac agaagtggcc agcttcaaaa
    17461 aacaagaaag aatttccgaa aatgcttctc aaatttttgt ggaattttag cgtattttac
    17521 gaaatagctg ctttctgaaa ctcccttcat cgagaggtcg tgacatagct tttgtcacga
    17581 tctctcggct tatcctacga gtattattcg atacatttat atcaataatc ctttttttat
    17641 tttatctgca gcttcttgga acgctccatc gtttgacacg actaaaagtg aggggatagc
    17701 tttcaaacgt ttcaactgtg ctaaatcttc tacataaacc gccagtctgg ctgaaatctg
    17761 ttcagatgaa tctccacgtt ttttcaggcg cgattgcaat gtttctttag agatcgtaat
    17821 aaagatagga cggactaccg tcccgaaata ctcatataaa tgccaaaaac catttgctgt
    17881 caaaacggcg taacaatttc ctactgtcag tttcttttta atttctgctt tactggaacc
    17941 atatttatgt tgagcatatt ggtcccactc tgcaaactca tttcccttga tcatctgatt
    18001 gaatgtattg tcagaaacaa aataataatc ctcttgatct ttttccccag gtcttggtga
    18061 tcgattcgtg taagtaatga tcttttgttc cggctgaaaa atagcttctg cgagtgaagt
    18121 ttttccagaa ccagaaggac cgataaatac atagcaataa ttcattgtca tttctccttt
    18181 gatgattgaa caagtgaaaa agctttggaa aatatttcca aagcttttaa aagtaacttt
    18241 gcttttttgt attttatacc agcaagccag tcacaatagc acttaaaaag ctgactaaag
    18301 tcgctgttag caaaattttc aatccgtgtt ttgcgacaag atttcctttt tcttcattta
    18361 atcccttcat cgcaccagaa atgatcccga tagaagagaa gttggcaaat gaaacgagga
    18421 agacagatat aattgctgtt gtacgctcag taaaatggaa attaccattt gctaattctg
    18481 tcatagcaac aaattcattt gtaaccagtt tagtcgccat gatactaccg gcatccactg
    18541 cttctttcca tgggattccg ctgatgaagg caagaggggc aaagatgtaa cctaggatct
    18601 cttggaaagt gatgccgaat atcccgtgga agatagcatt gatcatggca atcaaagcaa
    18661 caaaaccgat aagcatagca gcaaccgtga tcgccacatg gaaaccatca agaatgtatt
    18721 ctcccaacat ttggaaaaat gtctgttctt tgttttcttc aatgatcagc tcatcttctt
    18781 tttcttctaa tacataggga tttacaattg aagccagaat ataaccgcca aataagttca
    18841 aaacaagggc agtgatcaca tatttagaat cgatcagtgc catataagat ccgacgatcg
    18901 acatagaaac tgtagacata gccgatacac tcatggtgaa caaacgtttc tcagatagga
    18961 agggtaattc cttttttatg gaaataaaaa cttccgattg tcctaaaata gcagaagcta
    19021 ctccattata agattccaat ttgcccatcc cgttgatttt acttaatcct agaccaacag
    19081 ctttcataaa taatggaaga atcttgatat agcgtagaat accgataata gcagaaataa
    19141 atacaattgg catcaatacg gaaagaaaga aaggtgcact tcctttattt gctacaccgg
    19201 caaaaacaaa gtcaacacct tgcccagcaa aagcaagaag atgatcaaac atttttgcca
    19261 atacagaaac aaccgctgta ccaaaagttg tacgtaataa tacgaaacca agaacaagct
    19321 gtaaaacgaa catcacaatt agtggtttca atttgattgc ttttttgtta ctgctgatca
    19381 aaaaagcaag ccctaatgtg acaaataaac caataatacc taataaataa ctcaaataat
    19441 cactcctatt ccaaattccg ttttatttta cctgttttgc aaataaaata ctaatcttta
    19501 gtgaaatttt cattactttt ttagagtgaa acgcattcat tttccattag aaaataaagc
    19561 gaacaaaata aaaggtttaa aaagtgtaac gtcttagtaa agtctataaa aaaacgaaac
    19621 tatcgattaa gctaatagtt tcgttttcaa catttataag taaacttttt ctattggtaa
    19681 tatagatttt cggaagggta gacaggtgcg caggtaatat cgattcctag ttttttcaat
    19741 gtttgttcat catttttatt gaccatcaca gtagagtggg cttgtgctcc ctcaagttca
    19801 gctagtttat cataagcaac ttgagcgatt ggattcgtta ctgcactgat tgataaagcg
    19861 atcaagactt cattgatgct tagtgcatcc aaagaggaat gaagtgtctt tgatttcaat
    19921 ccttgtattg tttcaagaac taatggtgac aataaaggaa tgtcatctgc gatatgggct
    19981 aaatgtttta ctgcatttaa gataactgcc gctgacgcat ccatcaatga acttgtacgc
    20041 ccggtaatga tgacttcatc tggtaattcg attgcaatca cagcagaagg atcttttgta
    20101 ggactttgcg cttgaatctt atctgcatag tcatgggcag ggactaccac gtttcggtct
    20161 tcaggacgta aaccgacttc ttccataatc agtttgattc gattaactgc ttcttcgtcg
    20221 atcaatcctt ttttgaagtc gcattctgtt tggaaataac gacggatgat ttcttgttta
    20281 gaggcttctt ggacaacggt atcatccacg atcccaaatc ctacacgatt cacacccatg
    20341 tcagtaggag attgataaac agattcttta ccagtaattt tttcaataat acgtttgatt
    20401 acaggaaatg tctcaacatc ccgattatag ttcacagcta ctttattgta ggcatcaaag
    20461 tggaaggaat cgatcatatt gacatctttt agatcgactg tggctgcttc ataagcaatg
    20521 ttcagcggat gtttcaacgg aacattccat actgggaaag tttcgaactt ggagtaacca
    20581 gctgcatgtc ctttttggct ttcatgatac agttggttca agcaagtagc gagctttcca
    20641 cttcctgggc caggagctgt cactacaacg attggtttag ttgtttcaat atactcattt
    20701 tttccaaaac catcttctga gacgattttt tctacgttga ctggatagtc ttcgatttct
    20761 gagtgtttat agaccttgat gtttcgtctt tctagtttat tgataaagac tttcgtggca
    20821 ggctgtccac tatagcgagt gataacgaca ctgttgatta ataagccata accacgtaat
    20881 tcatcgatta accgcaagat atccatatca taagtaatcc cataatcacc acggatctta
    20941 ttacgttcaa tatctccagc atagacgcaa atcagtattt cagcttgatc tttcaatttt
    21001 tgcagcaatt tgattttcgc atcttcttca aatcctggaa gtacacgttt cgcatgcttg
    21061 tcgtcaacta acttcccacc aaattctaaa tataatttgt catagtggtt cactcgttcc
    21121 aaaatatacg ctgactgctc ttcaatatat ttttctgaat caaaaccaat ttttttcact
    21181 aggttccctc cttaagtact aaagcatttt ttcatttttt tgaggattcg tcaactggaa
    21241 gagcgaaatt cctcaaaaaa acaaagaaaa tggtttaaac caacttgtct agatagttat
    21301 tcattggtat gatagttttt gataaggaag gtgctacatg aaaaaaagac agaaaaagaa
    21361 aaacgcatat aaacactata tccgttcgat ttttaccggt tatgaaagaa tgcttgaaga
    21421 tcccgaattg gaacaattga cgtttactta tctaaacgaa gaaacgcagc taactcgtga
    21481 tgagcatcag cgcattcatt tcacaacaag agatctgcct agtaaataaa aaataagata
    21541 aaggtcatcg gattcgattc tgtcctatca gatggaaaga ctagttgatc gaaaaaaagg
    21601 ctgtaccaaa ttttggtgca gcctgtttta tggagcattg cccgctcttt tttataacaa
    21661 ttttttacag aaaatggtac tattgaagta ttaataagtg aaaaacagat gagtaagagg
    21721 aggcaagtag tatgaaagag ccagatacaa atgcaaatta tgagccagac gaactagagg
    21781 agacgaacgc ggatcaggat acaggacaag aatcgtcttc tttttacgat atcaaagaaa
    21841 aagcaagcat gaatctttcc caattattag aagacttaca ggcttttgaa aaagctgtcc
    21901 gcgaagaaga tatccctgag atctaccgtt tatacaatgg ccgattgaat gaagaattaa
    21961 aaagaagctc aaatgaaaat cacgagatcg atcaattgct gatgcgtaag atccatgatc
    22021 gttttttaca ggaatttcct tttatggaac aagtagaaaa catctcgcca acgatgagct
    22081 attacaaaat cggcacttat taccatgatc ggcccacggt cggtattgat gcaagtctgc
    22141 cagaaatttt tgttttgcct aagatcgatg aagagtggga gaaatattcc caaccggagt
    22201 caacggacta tgacaaaaaa atcaatgagc tagacgcaaa ggtgatcact gctcagacag
    22261 aaattgaacg tttagatgaa caaataaaag aaatcaatcg acaaatgact gatttgaacg
    22321 acaataaagg attcttgaat cgtaaaaaaa tcgaggaaga aattcaagaa ttagagaaga
    22381 agaagcaagt actatctaat gaaaaattag gctggcttcc ttatattgag acgcctgaaa
    22441 caatccagca gcaaaaagaa gcattgaagc aagaagcaag agcagaccag cttcgtgcag
    22501 ccatcgtaga aaaagaacaa aggcaaatca gacgctattt cggtagcaaa gagggattcg
    22561 gtcaagcaat ccatgaattc ttgatgaatt atcttggcaa tgagaatcct aataatcaat
    22621 ctaatgaagg aggttccgag tatgaatgaa cacgatgaag cagaatggac aaaaaatgaa
    22681 gaacaaacag aagatcatga agaaacgaac acttcattgg aagaacaaac aagtaatcct
    22741 ctggatgaca cagaagaaat ccctatgcta gaggaaacaa aaatacatga aaaagaaaaa
    22801 gtaactccga cgaatacgaa tactgcagaa aacacccatg cttacgaaat aactgaaaat
    22861 cccgggtatt tagaaggaaa agagcaagat catcaagata tcgtcagttt gattgaaaca
    22921 gcggaagcag aattagcgga tttacgtatg agaaaagatt tgatcgaatc agattttcca
    22981 caattattag aatcatatga tcgttttata ttgaatgaag aaccaatctc cacgatcgga
    23041 aagacaagcc tgatcgaata cttcacgtat gaattactga aaccgttgaa tgatattggt
    23101 ctggaacggt caaattcagc ttatgacaca tggaaaacaa gacatttttc gatcaattat
    23161 acgttgaatg gacaaaacga attagtcttt tcctttgtat taccgaccat cgatcaacga
    23221 taccaagtgg aatcgatgag tctcctaaac gtatcaccag agacaatgga aatcaatgtc
    23281 caagatgacc gggtgctttc tttgatccga cactggtcag tggatcgagt attctctgca
    23341 gggcagatca cgatattcaa tcacaaattg aatcaattat tagcccatgc aagaacactt
    23401 ggttttaccg ttaatcagac attactagac aatacgaagc cacttcgttt gaatcttcag
    23461 agcgaatttg aattgacgaa tgaagtattg gatgatattt ttatcgtggc aatgaaaaat
    23521 ccatcctacg atatggaaaa gatcaacgaa actacttatc aagtacgatt agataaagga
    23581 cagtctttaa cgataacaac aaacgaaaaa gatcaaacag tcttgtcgat ctcatctgga
    23641 gactacccac gatctgtcat tgatttcttt atcaattacg aattcttggt cccattaatg
    23701 gtgagaaagt cctgattgga taagttggat taccagatgt cattcagata attctgttcc
    23761 aaaggacttg cggcagttat ccagaataat tgtcacaagt cttttctgta tgtactaaat
    23821 ggacgtgaat aacttgctga tgaaggaggg atttcattag gaatgtccac aaataaaata
    23881 gcacagctta gcttattgtc tgctgcttgt gtagcaggta ggatcgcttt tcaatttatt
    23941 ccgaatttcc agccaatgac tgctattttt ttatttatag tactttactt aagcttaaaa
    24001 gatgcgttaa ttgtcatgag tctttctatt gcgatcagca gtttttattt tggtgttgga
    24061 ccatgggtca tcggccaatg gatcagctat actgttgttc tgagtttgtt ttcaatcgtc
    24121 tgcttgagaa aaacagtgca aaggaatcta tggttaaagg gagtctgttt ttttctggcg
    24181 ggcatggttt acggaatagg tatgaccgtt tttgatacgc tgttatatcg tttgcctcaa
    24241 ccttggatct attaccttca aggggtgtcg tttgatttga tgcacagtat aggcaatgtt
    24301 gtgttctttc ttgtttttct gccagtcgtc aaacgttttt acaatcattc aggaggaaaa
    24361 aatgaaaaaa ataatttata gtttgcttgc aatgagtgtc agtatactca ttttgacaag
    24421 ttgcagtaca acctatacac aatcggcttc caaccaaaag gaggaagtaa aaacatcgca
    24481 aaaagcaaca atcacgttac aagaaaatgg tcaaaacttt tcggaaaaag aagtggtctt
    24541 caaaaaaggc gatgatttac tgagtatttt gaaacgaaat tttgaagtca aagaagataa
    24601 cggcttcatc acttcgcttg aagggcactc acaggatgag aaaaatcaac tctattggat
    24661 gtttactgtg gacgggaaaa gtgctactac tggtgccaaa gagatcaaat tgaatgatgg
    24721 acaatcggtc attttcaatt tgtctaaact ataagtttca taaaaaactg ttaaagggcg
    24781 aatattgcca taattcagtg agttcagttg atgaaagaag gaaaataaca tggaaaattt
    24841 taaaaaaagc ggaatgtttt ccgtaattgc tgctctaggg gctaatattc tagttgctat
    24901 cagcaaattt gtcggctatg caatcagtgg cagtgccgcc atgctaaacg aaagcatcca
    24961 cagtatcgtt gattgcagca atcagatttt gctgttattc ggtgataaac aagccaataa
    25021 aggacagagc gagttgcatc aatttggtga aggacgagca aaatactttt tcagtacaat
    25081 cgtcgcaatg atgcttttct tcggcggtgg ggcacttggg gtgatggaag cttttgaaaa
    25141 gttgacgcat ccatcccatg aagtgggtaa tccgatcatt gttatagcaa tactgttatt
    25201 tggtttggta atcgaaggaa gttcgttacg cgtggcaatg aaagaaatca aagaattgaa
    25261 tactgaaaaa ctttccacga tgcgcttttt gcgcgaaagt cgacacagtg aaatactgat
    25321 tatttttacg gaagacttgt gtgctgtaat cggtttggtc ttggctttag caggaacaat
    25381 attgacttat gcaaccggga ttgctgcatt tgatgcgatc agcggattgc tgatcggttt
    25441 cttgctgatg ggagccgcca ttttcctagc aaaagaattt tatagtctga tcatcggtga
    25501 aagcgtgaca gcaagcgatt tatcaaaaat caagttagct tttgaacgtc ctgagatcag
    25561 tcggctgatc gatataaaaa cagttcattt aagtccaacg gagattttag ttgcagcaaa
    25621 agcagatatc gttggtaaca aagagaatga agcttactcg gtcatcaatg atattgaaaa
    25681 aaatatgcgt cagtctcttc ctgacaagaa gatgtatata tacattgaaa cagataaata
    25741 tgacccaaat tattctcgta aataaaacgt ttattcatga attgaagcaa aaatgagaaa
    25801 aatataatct tgtttttaaa taaaacggct acaatttagc gaatttatgt tacaatgagt
    25861 ccgctgttta tttgttgtaa ttaaaggaga tattttaatg aacaaaaaga aaagtgcgcc
    25921 atggcttcaa gctttgcatg cagtgatgcc actttgtata agctatatac cagtaggatt
    25981 agcttgcgga gtattgttgc aaaaagttgg atttgatcct ctcttatcag gactgttatc
    26041 gattctggtc ttttccggtg gcgcgcagtt tttagttgca tctatgctta cgacgcaagc
    26101 atcatttgca acgacattat tgatggtttt ctttttagaa ttacgctata cattattagg
    26161 agcaagtctt gccggtttta tgaaaaaaga aaagcggacg tttttggctg tcttttctca
    26221 atcactgaat gatgaaaact atgcggtgaa ctacttaaag ttttcaactg acccttcctg
    26281 gaataaaaga aaggctttat atgtcaattg gttctcaatg actgcatggg ccggtagcaa
    26341 tatgatcggt aattttttcg gctcggtgat tcgagtagat gctgaccttg tccattttgc
    26401 tttgacggcc atgttcattt tcatgtttat catgcagatg aaaagcgcac tactgatctt
    26461 tacaggttta ttctcaggcg tattaggggt cgtattcatg gtatttttcc aaaatacttt
    26521 cggattgatt gcagcaacag tcattgcttc atttgccgga tttatgctgg agaaggcatt
    26581 caaaaaagaa aaagctaaga aactaagaga ccgcggtaaa gatgtcaatg agccgctctt
    26641 caacttcccg gaacaggagg ccaatcacca tgactaaact atatttgcta cttttagttg
    26701 cttgtctgtt catcgtggca tatatcccgc gcttgttccc gatgctttat tttactcatc
    26761 gaaaagtgcc atcctggttc agtgactgga tgaaatatgt accggtggca ttatttgcgg
    26821 cgttagcttt taaagatgtt ttcattactc atgaacatct ggatattgct tggaatatca
    26881 aaatagctgc aatgattcta gtagcaggcg tggcttacaa aacacgttcg atggcgttgt
    26941 cagttttgac aggacttgcg tctgtctttt tgctgtctat gctttaaact gttttatttt
    27001 attaaaaaca gagattgcga cataagttgt tcaaactgat ctatccgaac tgcatttgca
    27061 acagtcaatt ctggatgcaa gtttattcgt agggataaaa aagattagtg ttggcttatg
    27121 atgcaagctc ttttttattt taggaattag agagggattt gtccttctat gattttttgc
    27181 tataataggg aagatgttta ttttatgaaa gaatagttga gggaatttaa atgaataaaa
    27241 aattgatgca aggaacattt tggctaacct ttgctaatct tctatgtaaa gttttagggg
    27301 tagtctattt gattccctgg ctaagtatga tggggaacaa tcaagatggt atgcttgcta
    27361 cgacattgta taatgttggc tatcttcctt atggattgtt cctgatgctt ggtacagtcg
    27421 gatttccaaa tgcgattgca aaaaaagtag ctgtagccac aaaagaagga gataacgctg
    27481 cttgtcggct gatttttaga agtacgatca atatcatgtt tgtcatcggt atcgcctctg
    27541 ctgcactgat gtatttattt gctcctttac tagccggaat cagtccgatt gctaacgtta
    27601 ataatgggat actagctatc agaagtttat gcccatcttt gattgctatc ccaattctta
    27661 gtgcaatgag aggatatttc caaggaaaaa atgatctgcg gccttatgga acttctttga
    27721 ttatcgaaca ggctgtgcga gtgatcgtta tcttggctgg tacttattac ttgcgcgtat
    27781 tgactgacgg aaccatatta gaagctgtat tgatcagtac agtcgcttct ttcttcggtg
    27841 ggttagctgc gattatccat atgtatatcg tcggacgcag aaaagacttc ttcgaactta
    27901 aagatttttt gatttccagc cgttatttcg aaagagaaaa ccgatctgcc tctgtctcta
    27961 tcattcggga aacactaccg tttatttttg tcggctcagt cattactatc gttcaaatga
    28021 tcgaccaagt aacgatgaaa ccactgcttc actttttccg tccagagatc gcagatcagc
    28081 aactggaatt cttattcagc cgtgcttctg tcaatccaaa taaattgaca ttgatcctga
    28141 tctccatggt aggaacagta gctataagca gcttgccaat attaagcacg atgaagaaaa
    28201 aagatcggat acaaatcgaa aaaacagtag gagatagttt ttcgattgcg ttattgattc
    28261 ttcttccttc attgactgga atgtctttat tagctggacc actatacaca ttgttttttg
    28321 gctatgatcc tgaaagtgtc ggatatttcc aaatggcttt gctagcttct ttgtttttct
    28381 ctttattcac gatcctatct acgatgcttc aatctttgaa tcaccatcgt tttgcgatcc
    28441 gattaactgt agaagcaatt atcctgaaag tcatcttcca agtaatcgga ttaggattag
    28501 ttggcggata cgggatgagc ttatcaaatg gcttagcatt cggtattgtc tttgttcgcg
    28561 gctatcactt tatgtgcaaa gaataccgaa tagcaccttt agcaaagatc agcaattttt
    28621 tcttaaaaac tttccgctcc accctgatta tgcttgcagt atgttttgcc gttttctttt
    28681 tgctgaatca gcgattgtca atggaatcaa aaagctatgc aatgatttat tgtgtggctg
    28741 taggaagtat tggcggctta gtatttttat tttctcaatt cggaaaaaat gggtttcgaa
    28801 tgttgaaaaa tgttaaacat catagcagaa gcaaagaata ggttaactaa tcgttttttg
    28861 ctgtcacttg aaaaacggca actcgtatga ttacgcttgt cgtttttcta ttttccaatt
    28921 ttagtttcat atctaatctt acttatgata tagttataag gtctggaaaa attctttgaa
    28981 acgaggaaat taaacacatg aaacttgcag tagttacaga tagttcggca tatctgccgg
    29041 aacgtatcaa gaaccatccc gacttattcg ttattccaat ccctttgatt atggatggga
    29101 aaatttataa cgaaggaatc gatatcgaag cggatgaata ttatggactt ttaaaaaaca
    29161 gtaaagattt tcctactact tcacaacctg tcgtagggga agttttgggt ttatatgagg
    29221 aattgaaaga gaaagggtat gacacgattt taagtatcca tctttcttca gggatttctg
    29281 gctttgtcaa cacattattt gcgatgaaag atgacatcag cggagtaacg gtcattcctt
    29341 atgactctaa gatcactagt atgccgatgg gacacatggt agaagctgcc ttagacttaa
    29401 atgatgaagg tcagtccctt gatgaaatac ttgcacatat cgatcgaatc cgagataata
    29461 cctatgctta tctgattgta gatgatttga acaatttagt acgaggagga cgtttgacaa
    29521 atggtgcagc gctgattggc agcttattaa aaatcaaacc gatcctgaca ttttctgaag
    29581 ggaaaattgt tttattcgaa aaaatccgtt caagtaaaaa agcatttgct cgagctgaag
    29641 aaattattgg tagaagaaat aacgaaatac aaccgccagt caaactttac gtgatacatg
    29701 caaataattt agaagtagcg attgcggaga aagagaaatt gcagaaaaaa tatccaaatg
    29761 cagaaatcga aattggtcat ttcggaccag tcattggtac acatttaggt gaaaaagcca
    29821 tcggcattgc catttcagcg caataattcc ttttattcaa aaaacatacc aaaaata
//
LOCUS       DAXLPY010000028        28270 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.028, whole genome shotgun sequence.
ACCESSION   DAXLPY010000028 DAXLPY010000000
VERSION     DAXLPY010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.028"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            147..1571
                     /locus_tag="ACF3UF_001378"
     CDS             147..1571
                     /locus_tag="ACF3UF_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFD3671519.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(1613..1870)
                     /locus_tag="ACF3UF_001379"
     CDS             complement(1613..1870)
                     /locus_tag="ACF3UF_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671520.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            2032..3141
                     /gene="pdhA"
                     /locus_tag="ACF3UF_001380"
     CDS             2032..3141
                     /gene="pdhA"
                     /locus_tag="ACF3UF_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFD3671521.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            3144..4121
                     /locus_tag="ACF3UF_001381"
     CDS             3144..4121
                     /locus_tag="ACF3UF_001381"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFD3671522.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            4146..5789
                     /locus_tag="ACF3UF_001382"
     CDS             4146..5789
                     /locus_tag="ACF3UF_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFD3671523.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            5797..7203
                     /gene="lpdA"
                     /locus_tag="ACF3UF_001383"
     CDS             5797..7203
                     /gene="lpdA"
                     /locus_tag="ACF3UF_001383"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFD3671524.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            7365..7640
                     /locus_tag="ACF3UF_001384"
     CDS             7365..7640
                     /locus_tag="ACF3UF_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFD3671525.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            7646..8413
                     /locus_tag="ACF3UF_001385"
     CDS             7646..8413
                     /locus_tag="ACF3UF_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFD3671526.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            8581..10410
                     /gene="typA"
                     /locus_tag="ACF3UF_001386"
     CDS             8581..10410
                     /gene="typA"
                     /locus_tag="ACF3UF_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFD3671527.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            10671..12443
                     /gene="recQ"
                     /locus_tag="ACF3UF_001387"
     CDS             10671..12443
                     /gene="recQ"
                     /locus_tag="ACF3UF_001387"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFD3671528.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            12557..12859
                     /locus_tag="ACF3UF_001388"
     CDS             12557..12859
                     /locus_tag="ACF3UF_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFD3671529.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            12862..14025
                     /locus_tag="ACF3UF_001389"
     CDS             12862..14025
                     /locus_tag="ACF3UF_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFD3671530.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            14051..17479
                     /locus_tag="ACF3UF_001390"
     CDS             14051..17479
                     /locus_tag="ACF3UF_001390"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFD3671531.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            17500..18624
                     /locus_tag="ACF3UF_001391"
     CDS             17500..18624
                     /locus_tag="ACF3UF_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFD3671532.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            18605..19051
                     /locus_tag="ACF3UF_001392"
     CDS             18605..19051
                     /locus_tag="ACF3UF_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFD3671533.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            19035..19373
                     /locus_tag="ACF3UF_001393"
     CDS             19035..19373
                     /locus_tag="ACF3UF_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFD3671534.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            19492..20052
                     /gene="rsmD"
                     /locus_tag="ACF3UF_001394"
     CDS             19492..20052
                     /gene="rsmD"
                     /locus_tag="ACF3UF_001394"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFD3671535.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            20049..20540
                     /gene="coaD"
                     /locus_tag="ACF3UF_001395"
     CDS             20049..20540
                     /gene="coaD"
                     /locus_tag="ACF3UF_001395"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFD3671536.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            20530..21573
                     /locus_tag="ACF3UF_001396"
     CDS             20530..21573
                     /locus_tag="ACF3UF_001396"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFD3671537.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            21732..22460
                     /locus_tag="ACF3UF_001397"
     CDS             21732..22460
                     /locus_tag="ACF3UF_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFD3671538.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            22576..22821
                     /locus_tag="ACF3UF_001398"
     CDS             22576..22821
                     /locus_tag="ACF3UF_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD3671539.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            22818..23036
                     /locus_tag="ACF3UF_001399"
     CDS             22818..23036
                     /locus_tag="ACF3UF_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFD3671540.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            23172..23711
                     /locus_tag="ACF3UF_001400"
     CDS             23172..23711
                     /locus_tag="ACF3UF_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFD3671541.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            23704..25977
                     /locus_tag="ACF3UF_001401"
     CDS             23704..25977
                     /locus_tag="ACF3UF_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFD3671542.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            26015..27061
                     /gene="holA"
                     /locus_tag="ACF3UF_001402"
     CDS             26015..27061
                     /gene="holA"
                     /locus_tag="ACF3UF_001402"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFD3671543.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(27150..27404)
                     /gene="rpsT"
                     /locus_tag="ACF3UF_001403"
     CDS             complement(27150..27404)
                     /gene="rpsT"
                     /locus_tag="ACF3UF_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFD3671544.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(27804..28073)
                     /locus_tag="ACF3UF_001404"
     CDS             complement(27804..28073)
                     /locus_tag="ACF3UF_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671545.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
BASE COUNT         9474 a         4849 c         6084 g         7863 t
ORIGIN      
        1 caagcttttg aacatcatta ttcagaataa gggactgtga taagattttt gtcacagtcc
       61 cttatgtttt gcaaaaaaag tttttctttt ttctcgtaaa ttcggtaaaa tcaaaagaaa
      121 aaatagacaa tagaaaagag aagcttatgt gggaaaaagt agagaaaaaa caaggaccga
      181 tttatcgtca aattatggaa cagattatga gagaaatcga aaacggaagg atcaatcctg
      241 gaagtcaact tgaatcagaa cgaaaactag ggcaactttt tggtgtgaat cgttccaccg
      301 ttgtccatgc attggaagag cttagggagc ttggggtact aacgagcaaa cgtggcagcg
      361 gatggtttgt taatcagact gaatggggga aattcgctgt tccaagaatc gattggcggc
      421 aaatgatctc tcctcgttat gagcagacgg actggtatga gcaaaaaata agagaagcaa
      481 agcagatcca aaaaacatcg tttcttgatt tatacgctag cgagatgcca gatgagcttt
      541 tgccgaattt tgagtttcct tcttattctc ttgaagaaat cttagcggaa gaaaaagaaa
      601 tggatctttt aggctatact ccgttacgta acaaaatcaa acggtatttg gaaagtaaat
      661 ttgaattggc attttccccc aaccagcttc ttgtgactgg tggcggtcag caagcaatct
      721 ttttgatttt acaaacgatt ctttcagctg gagaggggat agctgtagag tcaccttctt
      781 ttttttaccg attacctctt ttcaaagctt caggaacgcg tttatttggg ataccgatgg
      841 atgaagaagg gatcgactta gaaaaactga aagaatcgat ccataaaaat aaattgaaag
      901 cagtgcttat caacccgaat tttcaaaacc ctacaggaaa agtgatgagt caaaaacgac
      961 gagaaaagct agtagaattg tgtcgacagt atcggcttcc aattattgaa gacgatgtat
     1021 ttacggatct ttcatttcta aaccaagaag aagtccttcc tatacgaacg attgatccgg
     1081 ataatgtgtt atacgtcggt tcgttatcta gggttttagg aaaaacaacg aaaatcggtt
     1141 gggtgatagg acctgagact tttatctcgc aactagctca agcgcaagaa atgatggagt
     1201 tttcgatgaa tatccttaca caaatcacag tggctaatgt atttaatgaa gcaattgatt
     1261 tgaaaatgca agatgtaaga aaaaagttga aagaaaaaag ccgactgata agcgcttggg
     1321 gagattcaca atcgtttttc aagcttcatt caattttagg tggttactat gcctggatta
     1381 cttgggatgg gaaaaaacta gaccccgaac tagcagaaaa agtagtagat atgggtcttg
     1441 gaattgcacc aagtctactt tttgggcaag atataaatgg aatcagaatc aattacagta
     1501 ggctggatga aaaccaaata ccgttgtttt attcaaagat gaaaattcta gaaaagtggt
     1561 taacagaata atttcacaaa gtaaatagat taaagaatat aacagcttgg atttaaattt
     1621 caagctgttt cttttttttc ggaaaaagaa tacgatataa agaaactaag aaaaaaccat
     1681 tatttgtacg tccgttcacg atgtgtaaat aaaataaatg tttgcaacaa aactgtataa
     1741 caccaacgtt tttaaataga aacagatggt tgtaagtttg attagaaaat agaaaaaatg
     1801 cagatgaaat ataaaacgct ttccttattg tgattttatt cactaatgct gttaatatgc
     1861 ggattggcat aatttccttt catcgtgaaa atttgtgctt ttagcttgtg tttctcataa
     1921 atccatgata atttattaat gaagacggtt aaatagtgat acagttttat tcactgtttc
     1981 aatcgcagaa tgaagagatt ttcttataga tgagagagga atgtgtgaca aatggcaaac
     2041 aaaaaagcac cgatcgactt ccaagcactg ctagatgaag tcaatgcaga tttcccagta
     2101 tatcaagcac ttgatcaaga tggaaacgta gttaacaaag atttagtacc tgatttatcc
     2161 gatgatgaac tcgttgaatt aatgactcat atggtatggt ctcgtgtatt agaccaacgt
     2221 tcaacagcgc tgaaccgcca aggacgccta ggcttttttg caccaactgc tggacaagag
     2281 gcaagtcagc tggctagtgc ttacgcattt gataaagaag atgttcttct tccaggttat
     2341 cgggatgtac ctcaactagt aaaacatggt ttacctttat ctcaagcttt tttatggtct
     2401 cgaggacatg ctgcaggtaa ttcttatccg gaagaattga aagctctacc accacaaatt
     2461 atcatcggtg cacaatatgt acaagcagcc ggtgttgcat taggtttgaa gaaacgaaac
     2521 aagaaaaatg tcgtcttcac ttatactggt gatggcggtt catcacaagg tgatttttac
     2581 gaagcaatca atttcgctgg cgcttaccat gcaaatgccg tattttatat ccaaaacaac
     2641 gggtatgcga tctctacacc tcgtgaaaaa caaactgcag caaaaacact tgcacaaaaa
     2701 gctgtcgcag ctgggattcc tggtattcaa gtcgatggaa tggatccgct tgcagtatat
     2761 actgtatcta aaatggcacg ggaatgggcg atcagtggaa atggaccagt cctaatcgaa
     2821 acactgactt atcgttatgg accacataca ctatctggtg acgatccaac ccgctaccgt
     2881 acaaaagaca cagatgacga ttggcagaaa aaagatccat tgatccgctt ccgtaaatat
     2941 ttgacggaaa aaggactttg gtctgaagaa aaagaagaac aagtcatcga agcaactaaa
     3001 gaagaaatca aagcagctat tgctgaagcc gacaaagtac caaaacaaaa ggtttcagat
     3061 ttcttgaaaa acatgttcga agtatctcca caatcaatca aagaacaaat tgcaatttat
     3121 gaagcgaagg agtcgaaata atcatggcac aaaaaacaat gatccaagca atcacagatg
     3181 ccttagcact tgaactagaa aatgacgaga atgtcgttgt ttttggtgaa gatgttggga
     3241 aaaacggagg agttttccgg gcaactgaag gattgcagga aaagttcgga gaagaccgag
     3301 tattcgatac tcctttagct gaatctggaa tcgcaggatt gagtttcggt cttgcgttag
     3361 aaggatttcg tccagttcct gaaatccaat tctttggttt tattttcgaa gcaatggacg
     3421 aagtagtagc tcaaatggct cgtacaagat atcgaatgag cggcactaga aatctaccca
     3481 tcacaattcg ttcgccattt ggtggcggtg ttcatacacc agaattgcat tcggataatt
     3541 tagaaggttt gatcgctcag tctcctggta ttcgagtagt gattccttcc aacccttatg
     3601 atgcaaaagg actattgatt tcttctatta gaagtaacga tccggttgtt ttcctagaac
     3661 acatgaaact atatcgctca ttccgagaag aagtgccgga tgaagcttac gaagttcctt
     3721 tggataaagc agcagttact cgtgagggaa cagatgtatc tattatcaca tacggagcaa
     3781 tggtgcgtga agcaatcaaa gcagcagaca atcttgcaaa agaaaatata tctgttgaaa
     3841 tcattgatct tcgtacagtt gcgccattag atgtagaaac gatcattcaa tccgtggaaa
     3901 aaactggtcg cgtagttgtt gtccaagaag cacaacgaca agcgggcgtt gccgcgcaag
     3961 tagtttctga gatctcagaa cgcgctatcc tttcattaga agccccaatc ggacgagttt
     4021 ctgcacctga tacagtcttc ccatttggac aagcagaaaa tgtctggttg ccaaatgcaa
     4081 aagatatcga agacaaagta aaagaaatcg cggaatttta agaaaagaag ggacgaaaca
     4141 aagtcatggc ttatcaattt aaattgccgg atatcggtga aggaatcgca gaaggtgaaa
     4201 tcgtcaaatg gttcgtcaaa ccaggagata cgatcaatga agatgataca ttactagaag
     4261 ttcaaaatga caaatcagta gaagaaatcc cgtcacctgt tacaggaacg gttaaaaatg
     4321 tgattgttcc agaaggtacc gtagcaaatg ttggggatgt attagtagaa atcgatgcac
     4381 caggacacga agacaatgaa ggggacagtg gtgtagccgc agaatcccaa actccagcta
     4441 aaccggctgc tgaacccact gttgatacag aatcagctgg atcgtcaagc gaaggagtct
     4501 tccaatttaa gttaccggat atcggtgaag gaatcgcaga aggtgaaatc gtcaaatggt
     4561 tcgtcaaacc aggagatacg atcaatgaag atgatacatt actagaagtt caaaatgaca
     4621 aatcagtaga agaaattccg tcacctgtca cagggacagt taaaaacgtg attgttccag
     4681 aaggcactgt agcaaatgtt ggggatgtat tagtagaaat cgatgctcct ggacacaata
     4741 gtgcaccgtc aactagtgcg ccatcagctg aagcaccaaa agaaaaagtg gaaacatcag
     4801 gttcagcaag tgtcgttgaa gctgccgatc caaataaacg tgtattggct atgccatctg
     4861 ttcgtcaatt tgcccgtgaa aaagatgtag atatctcaca agtaactgca actggaaaag
     4921 gtggcagagt aacaaaagag gacatcgaaa acttcttggc aggtggtcca agcagtgcac
     4981 cagcgaaatc agaagcgcca gaagcggcag caccgaaaga agcagctcct gcagcagaaa
     5041 gcaaaccagc tgcaccagca aaaccattca agtccaactt aggagacttg gaagaacgtg
     5101 tagcaatgac gccaacacgt aaagctatcg ctaaagcaat ggtcaacagt aagcatacag
     5161 ctccacacgt gacattgcat gatgaagtag aagtgtctaa actatgggat aatcggaaac
     5221 gatttaaaga agttgctgct gcaaatggta cgaaacttac tttcttgcca tatgtcgtga
     5281 aagctttaac agcgactgtt aagaaatacc cagtattgaa tgcatctatc gacgatgcaa
     5341 accaagaaat cgtttataaa cattactaca atatcggtat tgcaactgat acggatcacg
     5401 gactatatgt accaaatgtg aaagatgcag accgcaaagg aatgtttgct attgcagacg
     5461 aaatcaatga gaaagcaaaa ttagctcatg acggcaaact atctgcagaa gatatgcgca
     5521 atggaacaat tacgatcagc aatatcggat ctgtaggtgg cggttggttt acaccagtca
     5581 tcaactatcc agaagtagct attttaggtg taggaacgat tgcacaacaa ccaatcgtaa
     5641 atgctgaagg cgaaatcgtt gtcggtcgtg tgatgaaact gtcattaagt ttcgatcacc
     5701 gtatcgtaga tggagcaact gcgcaacaag caatgaataa tatcaaacgt cttttagctg
     5761 atccagagct attaatgatg gaaggatgat aaacaaatgg tagttggaga ttttgctgta
     5821 gaattagata cagttgtaat tggtgcggga cctggtggct atgtagctgc catccgcgct
     5881 gctgaaatgg gacaaaaagt agcaatcatt gaaagagagt atattggcgg tgtttgtttg
     5941 aatgtcggct gtattccttc aaaagcactg atagctgcag gacaccatta tcaagagtca
     6001 ctagattctg aaatgtttgg agtaactagt gaaaacgtca aactagattt tgcaaaaaca
     6061 caagaatgga aagaaaacaa agttgtccat acgttgactt ctggtgttgg tttcctatta
     6121 aaaaaacata aggttgaaac aatcgaagga gaagcgttct tcgtagatga tcacacacta
     6181 cgcgtcattc atccagattc agctcaaact tattcgttca ataacgcaat catcgcaaca
     6241 ggttcccgtc caatcgagat tccaggattt aaattcggag gacgtgtgtt agattctact
     6301 ggcggattag cattgaaaga agtacctaag aaatttgtga tcatcggtgg cggtgtgatt
     6361 ggtgccgaat tgggcggagc gtacgcaaac ttaggagcag aagtaacgat tcttgaaggc
     6421 tcaccacaaa ttttaccaac ttacgaaaaa gatctagtaa aattagtaga agatgatttc
     6481 aagaaaaaag gcgtaacagt cgtaacgaat gcaatggcga aagaagcagt cgataacggt
     6541 gacagcgtga cagtgaaata tgcagtggac gggaaagaag aatccgttac tgctgattat
     6601 gtgatggtca ctgtaggtcg tcgtccgaat acagatgata tgggcttaga acaagcgggt
     6661 gtcgaagtag gagaacgagg attgatcacg gtggataaac aaggacgtac gaacgtacct
     6721 aacatctatg ccatcggtga tatcgttcca ggggcggcat tagcacacaa agccagttat
     6781 gaagcaaaaa tcgctgctga agcaatctct ggcaaaaaag tagctgtaga ttataaagca
     6841 atgccggcag tagccttcac tgatcctgaa ttggcttctg taggtatgac gatcaaagaa
     6901 gcaaaagatg ctggtatcga agcaaaagca tataaattcc cattttcagg gaacggtcgg
     6961 gcattatcgc ttggtaaaac agaaggattc atccgtctag ttacgacgat cgaagataac
     7021 gtgcttattg gcgcgcaaat cggtggagtc ggcgcaagtg atatggtctc tgaattagct
     7081 ttagcaatcg aatcaggaat gaatgctgaa gatatcgcct tgacgattca tcctcatcca
     7141 tctcttggcg aaatcgtcat ggatgcttcg gaattagcat taggtttacc aatccatatt
     7201 tgatttgaat aatacaggcg aaacgcaact gaaaaatcag ttgcgttttg ttttttagaa
     7261 ttatcaataa tattattatg taaacttaaa aatatgacaa cttcttggtt tattaccact
     7321 tcctatgcta cactgaagag gaatatgaaa taggagagtt gaagatgcaa gaatatcagt
     7381 atccacttga tttagattgg acaacagacg aaatggtcat tgtaatgaag atgtgggaag
     7441 atctggaacg tgcgaatgaa aaagggataa acaatgaagc ttttttgaag acttatcagc
     7501 agtttaaaac tgttgtcaaa tccattggtg aggaaaaacg attgggacgg gaatttgaaa
     7561 aagcttccgg ttattcttta tatcgtacag tgcagcaagc aaaaaaaaat ccaaacaaaa
     7621 ctttgagaat gaacgggtga gataaatgga acagatgatt gatcatatca agtcctggct
     7681 tgaagaagct ggtgagaaaa tcaaatcttc tcaacaaaca ttaacaatct cgcaaaaatc
     7741 aaatcgaacg gatctagtaa caaatgtcga tcgaaacatc cagaattttc taatcgaaaa
     7801 aatccattcc tttgatccag aggcgaaaat attggcagaa gaagaagggt gtaatcaatt
     7861 atcggatctc gatggaagag tctttatcat cgatcctatt gatggcacct tgaattttgt
     7921 gattgaaggg gaaaattttt gtattatgct cgctgtttat gaatccggcg ttggaaagct
     7981 tggtttcatt tatgacgtga tgagaaatga acttttttgg ggtggaaaag gaataggcgt
     8041 gtataaaaat gatgagccat tgcctagacc agcaaataaa tccttatcgg aaggcttact
     8101 tggtgtgaat agttatcttt tcggtcataa taaatatgga atccgagaaa ttgcggaaag
     8161 cagcatgggg acacgtatgt acggatgcgc tggtcttgaa ctagtggcaa tcttgaaagg
     8221 aaaccacatt gcttatattt caaaccttag cccttgggat tatgcagcgg gaaatgtctt
     8281 attggaagag tttggtatgg taacaagcgg tctttttggt actcctttga catttgaaaa
     8341 aagggaatac tatttagcag ggacttcttg tgcatatgca gaaatcgcag accttttgaa
     8401 aaaagaaggc tgaaaaaaag gtagaaatca ttcacaaaaa tgataaaaac gagcaaaaga
     8461 ttaattttct cgaaaaaatg aaaacatttt actatatttc atgaaaaaag tctgctataa
     8521 ttagcagtcg agtaaaattt gccctgtcat aaagaaccaa taaaaaagga gttagttaca
     8581 ttgaattata gaaacgatat ccgtaacgtc gcaattattg cccacgttga ccacggaaaa
     8641 acaacattag ttgatgaact attaaaacaa tcagatacat tagacgcaca tacgcaattg
     8701 caagaacgtg cgatggactc aaatgcgcta gaaaaagaac gtggtatcac gattttagcc
     8761 aaaaacacag ctgtagacta taaaggtatt cgcgtaaaca tcatggatac tccaggacac
     8821 gcggacttcg gtggcgaagt agaacggatc atgaaaatgg ttgacggcgt tgtgttggtc
     8881 gtagatgcgt atgaaggaac aatgcctcaa acacgttttg tattgaaaaa agcactggaa
     8941 caacatatca caccaatcgt tgtcgtaaac aagattgaca aaccttctgc tcgtcctgag
     9001 catgtcgtag atgaagttct tgaactattc atcgaattag gagcagatga tgatcagtta
     9061 gactttcctg tgatttatgc atctgcacta aatggtacgt caagcttgtc agatgatcca
     9121 gcagatcaag aaccaaccat ggcacctatt tttgatacaa ttattgaaaa aatccctgct
     9181 cctgtcgata acagcgacga accattacaa ttccaagttt cattacttga ctacaacgat
     9241 tatgtaggtc gtatcggaat cggacgtgta tttagaggaa caatcaaagt aggagaccaa
     9301 gtagcattaa ttaaattaga cggaacagtt aagaaattcc gtgtaacgaa attatttggt
     9361 ttctttggac taaaacgtct agagattcaa gaagcaaaag ctggagactt gattgctgtc
     9421 tcaggtatgg aagatatctt tgtcggtgaa acagttactc ctgtggatca tcaagatgcg
     9481 ttacctatcc ttcacattga cgaaccaaca ttgcaaatga ctttcttagt taataattca
     9541 ccatttgccg gtcgagaagg taaattcgta accgctcgta agattgaaga acgtttgatg
     9601 gcagaacttc aaacagatgt atccttacga gttgaaccaa caaactctcc agatgcatgg
     9661 acagtttctg gtcgtggaga attgcatttg tctatcttga ttgaaaacat gcgccgtgag
     9721 ggatacgaat tgcaagtatc tcgtccagaa gttattgaaa aagaaatcga cggtgtaaaa
     9781 tgcgaaccgt ttgaacgcgt gcaaatcgat acaccagaag aatatatggg tagtgttatc
     9841 gagtccttga gcttacgtaa aggtgaaatg caagatatgg tccatacagg aaacggacaa
     9901 atccgtttga cattcttaac acctgcccgc ggtttgattg gttattcaac tgaattcctt
     9961 tcaatgacac gtggttacgg aatcatgaac catacttttg accaatatct gccaatgctt
    10021 cctggtcaaa ttggcggacg tcaccaaggg gcgcttgttt cgatcgatac aggaaaagca
    10081 acgacttatt ctatcatgag tatcgaagaa cgcggtacag tcttcgtaga accaggtaca
    10141 gaagtatatg aaggaatgat tatcggggaa aacagccgtg ataatgattt gactgtcaac
    10201 atcacgaaag caaaacaaat gacaaacgta cggtctgcta ctaaagacca aacatctgtc
    10261 atcaaaaaac caaaacaatt gacgttggaa gaatctttgg aattcttgaa tgatgatgaa
    10321 tattgcgaag taacaccaga aagcattcgc ttgagaaaac aaattttaga gaaaaatgct
    10381 cgtgaaaaag catctaaaaa gaaaaaataa tctgtaaaag gatgaagaga gaaaccagct
    10441 tgttataaaa aatagctggt ttcttttttt gtccaactct tttctgtgga gaagtcatct
    10501 ttgtcaatgg acataaattc agaaaatacg ccgaaagacg tttaaaagac ttttaaaaaa
    10561 cttatttcta gagagttttt gtttcataat aagataatgt ttcacgaaag gagatcaact
    10621 tgtccttcga agaaaatcga agtaaaatgg caagagaaag gagcgggaag atgaacgact
    10681 tattaaaaca atactttggc tatgatgagt ttagacctgg tcaaaaagaa attatccaga
    10741 aagtcattga tcaggaaaat gtattaggaa tcatgcctac cggaagtggg aaatcaatct
    10801 gttaccagct tccagcttta ctattagatg ggcttactgt ggttgtgtcc cctttaatct
    10861 ctttgatgaa ggatcaggtg gacgcggcga atcaattagg tatacccgcc acttttatca
    10921 atagctcgtt agatggttac gaaacagcta gacgcttcca agaaatcgat agacagcagt
    10981 accgtttact ttatatcgct cctgaacgtt ttatcatgcc ggattttatc caagcaatga
    11041 agcgatggaa cgtccgtatg atcgctattg acgaggcaca ttgtatctct cagtgggggc
    11101 atgatttccg cccaagttat ttacagatgg cgaaccagct agatcaactg ccaaatcgtc
    11161 ctgtaattgt tgctttgaca gctacagcga ctgtgcaagt agctgctgac ataaaaagac
    11221 ttttaaaaat tccagaaaac aaccatattc agactggttt tgaacgagaa aatctacgat
    11281 ttcaagtaat taaagatcaa aaaaaagaac aatatctaat cgaatattta aagatcaaca
    11341 aaaatcaatc tggtatcatt tatgcagcaa cgagaaaaga agtagaccgt ctctatcatt
    11401 tgcttaaaaa attcgatttt tccgtgggta gatatcatgg tggtctaaat gagaatgagc
    11461 gaacagaaat gcaagaagcc tttttatacg atcgcttgca gctgattgta gcgacaaatg
    11521 catttggtat gggtataaat aaaagcaatg tccgttttgt tatccattat caaattcctg
    11581 gctctctaga agcatactat caggaagctg gtcgggcggg aagagatggt ctttccagtg
    11641 aagccatcct gcttttctct cctcaagata tccaagtcca aaagtttttt atccagcagt
    11701 cccaaagaga agaagggcaa aagcaaaaag aatatgaaaa attaaaagcg atgacagaat
    11761 acgtgtatat tgagtcctgt cttcagcaat acatcctaaa ctattttggc gagacaagca
    11821 gtccgtgcaa ccgttgtggt aactgtttag atgacagaga aatagtagaa gtaacgacag
    11881 aagcacagat ggttctttct tgcttaaaac gtatgggtga gaactatggt aaacaaatgc
    11941 tgatgaaagt cttagcagga tcgaaagaac aaaagctgca agctttaggt tttggacatt
    12001 tatctaccta tggactgatg aaaaaccaat cgcaaaaaga aacgatgcag ttaattgaat
    12061 atttgatatc gaatggctat cttctgacca tcaatggtga gtatcctgtt ttgaaagtaa
    12121 cagaaagagg gatacaagta ttgaaaggac aagaatctgt ttatcgaaag gaacccaaga
    12181 aagtccagca gctatcggat gaagaaaccg atacactatt tgaagtgctg cgggaactgc
    12241 gaacggatct agcatcagaa gcaggcgttc ccccgtatgt cgtattttca gattccacat
    12301 tgaaagaaat gagccgaata cgtccatcaa gcagattgga gatgcttcag ataaaaggag
    12361 ttggccaaag caagcttgat aaatatggcg aagccttttt atctcggata aaaaatgcgg
    12421 actctaacgt tctggataag tagaaagaac gaatacgtaa aaatgaataa aaacaactgg
    12481 ttaaatctgt tttttttgct ccttatgaaa atcaaatatg ttataattaa ggaattagaa
    12541 tgggaggtaa gcacagatgg attctttgtc gaaaaaactt gcgatccaag tattaaatga
    12601 tgaagcagaa cggatcaaac gattaatccg aaatcaaaac aacagtctct gtatctcaca
    12661 atgcaaagcc ttcgaagaag tggtagatac acagatgtac ggcttttccc ggcaagtcgg
    12721 ttttgctgtc cgtataggag taatcggaaa gaacgagggc cagctgatgt taagtgagct
    12781 agaacgagaa ttgaatcagt tatatagtga ggtttaccaa gaaatttatg ataaaaaaga
    12841 agttggcaag gaggaataga cttgcctaag aaagtgaaaa aaaggcatct attagactat
    12901 agcatcttga ttccctattt aattttatgt gtattgggat tgatcatggt atatagttct
    12961 acgtcgtatc tattattaga aaacggacaa aatccgtccg catcagtcat taaccagagt
    13021 attttttggg tgcttagctt gattgctatc gcactacttt ataaaatgaa aacagatgtt
    13081 ttgaaaaacc agcgtttgat catggcagcc atcgcagttt tgacgatttt gctgctgatt
    13141 gttgtgtttt ttggtaagga gatcaatggg gcgaaaggtt ggctgcaaat tgcaggattc
    13201 tcgatccaac ctgccgaata cctaaaaatc atttctatct ggtacctgtc tctgacttta
    13261 tctaaaagac aaaacagtgt acaaaaagat tttcttggga ctgtgaaacg tccacttgca
    13321 atggttatcg gacttactgc attagtcgct attcttcccg attttggtaa tgcggcagtt
    13381 atctttttga ttattttggt tctgctttta gccagcggag tcaattatgt gtatactttg
    13441 attgtaggag taggaggctt ttgtctaagt acttttacga tctggctgat caatatcaca
    13501 aacggaaaga tcttacccgg acgtttacag tatatctata atcgatttgc tatttaccaa
    13561 aatcctttct cagacgaatt aaataaaggg catcaactag tcaacggcta ctatgccatg
    13621 ttcaacggag gactatttgg caggggatta ggtaacagta tccagaaaaa aggattttta
    13681 caagaagcac aaaccgattt tatttatgca atcgtagtgg aagaactggg agtgattatg
    13741 gggattttga tattagcgtt gctattcttt atgattgtgc gcattgtcct tgtaggtatc
    13801 cgttcaaaag atccgttcaa ttcgcttttg tgcattggga tcggcgcaat gtttttgatc
    13861 caagtatttg tcaatcttgg agggattact ggcgttattc ctttgacagg gatcacgttc
    13921 ccatttttaa gtcaaggagg ctccagtttg ctgatgcttt cgatttgtgt cggctttgtc
    13981 ctcaacatca gtgcggatga aaaacgcaag agcttaggtt tataataaaa aaagatgtag
    14041 gagtggttcg atgaaaaaag ttttagttgc taacaggggt gaaatcgctg tacgtgtatt
    14101 tcgtgcttgt acagaattag gaattaaaac tgttggaatc tatgcagaag aagatgaata
    14161 ttccgtacac cgtttcaaag cggatgaagc atatttagta ggacaaggaa aaaaaccgat
    14221 tgatgcgtat ctagatattg aagggatcat ttctatcgcg aaagaatgcg gagctgacgc
    14281 tattcatccg ggttacggtc ttttgtcgga aaacttgaat tttgcgcaac ggtgcgaaga
    14341 agaaggcatc atttttgttg gacccaaact gcatcattta gatatttttg gagataaaat
    14401 caaagcaaaa gctgcagcta tcgaagcggg gattgcttcg attccaggca cagatggacc
    14461 aatcgcttct atagacgatg ccttggagtt tgcgaaacaa tacggttatc cgattatgat
    14521 caaggcagct ctaggcggcg gcggacgcgg catgcgtgta gctcacgatg aaaagagtgc
    14581 aagagagggc tacgaacgtg cgaaaagcga agcaaaagca gcctttggta gtgatgaagt
    14641 gtatgttgaa aaatacatcg ctaatcctaa gcatatcgaa gtacagattc tcggggatac
    14701 gcatggaaac gtcatccatc tttttgaaag agattgttct gttcagcgcc gtcaccaaaa
    14761 agtagtagaa gtagcgcctt gtgtctctat gaatgaacag caacgtcaaa aaatctgcca
    14821 ggcagctgtc caattgatga aatatgtcgg gtatgtcaac gcaggtacag tagaatttct
    14881 tgttgaagga gatgattttt actttatcga agtcaaccct cgcgtccaag tggaacatac
    14941 gatcacagaa atgattacag atattgatat cgtaacaacg caactgttga ttgctcaagg
    15001 tttggatctg cataaagaaa tcggattgcc tcagcaagaa ggaattaaat taaatggttc
    15061 agccattcaa tgccgaatca ctacagaaga cccgttgaat aactttttac cagacacagg
    15121 gaaaatcgat acgtatcgtt cacctggtgg ttttggcgta cgtctggatg tcggaaatgc
    15181 ttacgcgggc tatgtagtga caccgtattt tgattcattg ctagtaaaag tatgtacgca
    15241 tggtgctacc tttgaaacag ccattcagaa aatggaacgt tgcttgaaag aatttagaat
    15301 ccgtggagtg aaaacaaaca ttccatttat gctcaatgtc atcacacatc ctgaattcca
    15361 atcaggaaat gcaaaaacaa ccttcattga tagtacagca acattatttg aatttcctcg
    15421 actacgagac cgcggaaaca aaacgatgaa atatatcggt gaaattactg tgaatggttt
    15481 tccaggtatc gaaagtggcg aaaaaccatt ttatgaagaa ccacgtatgc ctaaagatct
    15541 aatcacaaga actgattacg taacggctaa gaatgtatta gatgcgaagg gtgccgatgc
    15601 tttggtcgaa tggatcaaag gacaggaaaa tttgttgttg acggatacga catttagaga
    15661 cgcccatcaa agtctgctag caactcgtgt tcggacaaag gatttcaagc agattgcacg
    15721 tttgactgga gaaggtcttc ctgaactctt ttcaagtgag atgtgggggg gagcaacatt
    15781 tgatgtggct taccgctttt tgaatgaaga tccttggcaa cggttgagaa aaattcgttc
    15841 tttaatgcct aatacgttgc tgcaaatgct tttcagaggt tcaaatgccg ttgggtattc
    15901 taattatcct gacaatgtat tggtggaatt tgtcaaagaa gcagcagcgc aaggaatcga
    15961 tgtatttcga atctttgata gtttgaactg gactccacaa atggaaaaaa gtatccaagc
    16021 tgtacgggat actggtaaaa tcgcagaggc agctatttgc tatactggcg atatcaacga
    16081 tccaagtcgg gcaaaataca atgttcagta ttataaagac atggcaaagg aactagaaca
    16141 actgggtgcg catatcattg caatcaaaga tatggctggg ctgcttaaac cgcaggcagc
    16201 ttatcgtttg attagtgaat tgaaagaaac gacagatctg ccaatccatc tgcatactca
    16261 tgataccagc gggaatggaa tcatcactta ttctgctgct tcaaaagcag gagtagacat
    16321 cgttgacgtg gcaatgagtg caatgagtgg gaatactagt cagcctagca tgagcagctt
    16381 gtattatgca ctggtcaatg gtccacggct gccagaaatc acgattgaaa atgcacagaa
    16441 attaaaccat tattgggaag atgtgcgcat gtattacaaa ccgtttgaaa acggcttgaa
    16501 tgctcctgaa acagaagtat atatgcatga aatgccagga ggacagtatt cgaatctaca
    16561 gcaacaggca aaagctgtcg gattaggtca tcgctgggat gaaatcaaac aaatgtatca
    16621 tactgtcaac ttgatgtttg gcgatatcgt taaagtaact ccatcatcta aagtagttgg
    16681 agatatggca ctatttatgg tccaaaatga tcttacagaa gaagatattt atgaaaaagg
    16741 cgaaacacta agtttccctg aatctgttgt gactttcttc caaggagaac tagggcaacc
    16801 cgttggcgga tttcctaaaa aattgcaaaa gattattctt aaaggcagac ctgcattgaa
    16861 tgaacgtcca ggtcttttgg ctgaatcagt cgacttcaac gaagtaaaaa aagaattggc
    16921 agaaaaaatt ggctatgaac caaaacaaga cgaagtatta agctatttga tgtatccgca
    16981 agtctttttg gactatcaaa aagcatataa tcaatttggc gatgttacat tactggacac
    17041 accaacattt ttccaaggta tacgtttggg tgaaacaatc aatgtacaaa tcgaacgcgg
    17101 aaaaacgctt atcattcgtt tagatgaaat cggagaaccc gatatcgaag ggaatcgcgt
    17161 actgttcttc aatttgaatg gacaaagacg tgaaatcact atcaaagata attcgatcat
    17221 cagtacggtc caaacccgat tgaaagctga accgacaaac cgagaacaaa ttggagcaac
    17281 gatgtctggt tctgttttgg atgtattagt gaaaaaaggc gataacgtta aaaaaggtga
    17341 tacgttgatg attactgaag cgatgaaaat ggaaacggcc atcgaagcac gttttgacgg
    17401 agaagtcgca catgtatatg tgtcttcagg agacactatt tcgtctggtg accttttgat
    17461 tgaagtgact gagaaataat aagcgaaagg tggggaaaca tgaaaagact gggtttgttt
    17521 tggctgattc tgctattagt tattgtggca ttctacatgg aaccagtctt gtttccgcca
    17581 aaacttgaag tgaaggaaaa ctctgatcaa caaatatcaa accaaatgac aacgtggaaa
    17641 taccaggagc ttaaagcaac tggtttttct acttatatcg gaaaaccgat cgatcagctg
    17701 gaaaaggatt ttggccaagc ctatgatcga ttaactagcg gatttggttt tgaaacaaga
    17761 tattatgaaa ataaagctag tcatctcaca tttgaagcga acatccaaga cagcagagtc
    17821 acaactgtta aagtactgca aacagggcct gctgatatcg cgccgtttta tttagggatg
    17881 acgatgcaag atcttacgaa aatcactact atctatacta atttcacttt tgagtaccat
    17941 gatacagaag ttggaatcga actaatggaa gaggatatga attatcgtcc gctaattgct
    18001 tttgataacg acacttttgc tattttattt tttgatcaaa caacaaacgg cctattttca
    18061 gttgtgtatt tagataaaga tagtcttttg aaactattgc catatcaagt gtttggtgaa
    18121 ggccttccac attatcaagc agataaatcg gctgattggg aatcaatcaa tcgcgttaaa
    18181 gaacgaaaaa gtacgacttt attaaatatg cttagaagag aagacgaact tcccatatac
    18241 aatcaaacac ttgcctttca aaaccacagt cagctgctac tacatgattt tttgacaagg
    18301 cctgaggaaa tattgtcaga ggaacgtatg gctgattggc aaaaatcgct aggcagtgct
    18361 caaacgacag tgaaattctc actgacgaat gatgaattgg agaagttaat cagtaaacaa
    18421 aaattagaaa atactagtgg gctatttatt catccggcga ttgacgctac tttttcgttt
    18481 ttatattggt acagcgatcc ttacaaccat gaccgtttca tggacccggg aacggattct
    18541 gtaggcattg ctttttctaa agaaaatatg ttagtcttat tgcaagaaga aaacggagaa
    18601 agtagtgata gcagtgatcg ttaacgaaga gctgtttcaa ctggaggatc aatgcctcca
    18661 agtcgctgaa atgataaaaa agagtaaaac gatggcttct tatcttgaac ataaacagtc
    18721 aatggaagaa tctgcaaaag tttgccagtt gaaagaagcg ttcttgtcta agaaagaagc
    18781 atttgaaaat gtagcggcat atggtgagta tgcacctgat tatcgtgaaa aaaaacgagc
    18841 tgttcgaaaa gcaaaaagac agcttgatat ggatgagcat gttgcagctt tccgatatag
    18901 tgaaacacag ctgcaaagtc tgttggatca aattgtccaa gtacttgccg aagaagtttc
    18961 taatgaaatc aaagtagatg caggtagccc gttttttgaa acgaaaaaac actttggatg
    19021 cggaggtaat tgtcatgcaa ttagacaata gtgaatttga aataacaaaa cgacgcgggc
    19081 tgatcgtatg ggtctacagc ttaaaacaat taaagaatct gaaaaagttc ggcttgttgc
    19141 attatgtctc aagaagaatg aaatatgtcg tgctttactt aaatgaagag acattggaag
    19201 aaacagaaga acgaatccgt aaattacatt ttgttcgaaa cgtagaacgt tcttaccgac
    19261 cggatatcga aatgaatttt gccgaaaaaa taggaaacaa aacagtatta aaagacgaag
    19321 gtttcgaaat tgaagagcta aatacagaaa tccgattagc tgaacatctt taaaaatctc
    19381 ttatgagcag tttttaaata aaaaataact tggataacga tcgatttttg atcattgtcc
    19441 aagtattttt ttggtatact agtaccagta ccatttctaa ggagtgagta gatgcggata
    19501 atatcaggaa attatggcgg gcgccgttta aaaagtttag caggggcgaa caccagacca
    19561 actacagata aagtaaaaga atccatattc aatatgattg gaccatattt tgatggagag
    19621 acagtattgg atctgtttgc aggaagcggt ggtttagcta tcgaagcagt atctagaggc
    19681 tgcagtcatg cggtatgcgt agacaaaaat taccaagcgc taaaaatcat caaagaaaac
    19741 atcgaaatta cgaaagaacc agagaaattt accacaataa aacttgatgc ggacaaagca
    19801 atcgaacggc tagcagcgga gaaacaacaa ttcgactact tgtttcttga tccgccatat
    19861 gcaaaacaaa aaataatcga tcaaatccat aaaatggaag aactgggact tttttctaaa
    19921 accgcagtta tcgtatgcga aacggataaa acagtcgaat tgccagaaac tgtggctgga
    19981 ttccatcaaa taagaaaaca gatttatggc ataacggccg taactatcta tagaaaagag
    20041 ggaaatcaat gaaacgtgca ttattcccag gaagttttga tccttttaca aaaggtcact
    20101 tagatacggt ggaacgtgcg gctaaattat tcgatgaggt agtaattggt gtttttatca
    20161 atacttcaaa gaaaagtttg tttcccccag aagaaagaat gacattgatc acaaaagctg
    20221 tttctcatct tcctaatgta aaagtcatgc atcaagaaaa tcaattgacg gtagaaacag
    20281 caaaagagat tggtgcagat gcgttgatca gaggcatacg aagtatcaaa gactttgaat
    20341 atgaacgaga gattgctcag atgaatcatc atctatatga tgaattggaa actgtcttct
    20401 tattagcaaa accagaatat agtcacgtga gttccagtat tttaaaagaa gtactgcact
    20461 ttggcggaga tgtgagcagc tacttaccgc cagtgatcaa cgaagcttta gctggaaagc
    20521 gtgaatcaaa tgaaagctaa acaatggttg aaaacagtac tgattatcat atttggaatg
    20581 ttgatcattg gatttgtagt agttcccttg ccgtattatg tagaatcacc gggagccacg
    20641 atcgatctga aagaactaat tacggtcaat gataaggaag ataaaggttc tgggtctttc
    20701 tctcttacct ctgttggtat caggcaagct acaggtttct tagctttaaa agctaaaatg
    20761 accccttttg aagaattgat cagtgaagaa gaattgactg gtggggcgac aaatgaagaa
    20821 tataatcaaa tgcaacagta ttatatggat tcttcccaaa atgcagcaat cgaacaagcg
    20881 ttaaaacttg cagacaagcc ttataaaatg gaattcaaag gcgtatatgt catgagtgta
    20941 gagaaaacat cgaatttctt tggcaagctt tcagttggag atacagtaac aaaagtagac
    21001 gggaaaagct ttcaaagtac agaagcattt atggattatg taaaaagcca aaaagttgga
    21061 caaacaatcg aaatcagtta tttgcataat ggtgaagaaa aaacagcttc tggtgatctg
    21121 atcgagttac caacagataa aaaggcagga ataggtatca cgcttactga ccataccgag
    21181 atcgaatcag atacagatgt tcgtattaat tctggctcta tcggtgggcc atcagcggga
    21241 ttgatgttca ctttagaaat ctatgaacaa gtcactggta aaaacttgcg acatggtaag
    21301 caaattgcag gaactggaac gatcaacagt gaaggagaag ttggccgaat cggaggaatc
    21361 gataaaaaag tggcaagtgc ggataaagct ggcgtagaga ttttctttgc accagatgat
    21421 acgatttcag acgatgttaa gaaagaatat cctgaaataa aaaccaacta cgaagaagca
    21481 aaagctgccg ctaaaaaatt gaattcctca atgaaaatcg taccagtaaa aacagtacaa
    21541 gaagcgcttg actatctaga gaaaatgaaa tgaaactaaa taattaaaga ggggttgtga
    21601 cacgagttct gtcacaaccc ctctttttcg tcaaaaatct tcacgataaa aataaaaaca
    21661 aaagaaaaaa ttgacgtaat tagatgttga agggacgatt ttgccagagc tcactgtttc
    21721 ttcaatttta aatgaaagga gtaatgaatg atttttactg gtcattcttt gaaaaaagaa
    21781 caatgataga aaaaatcagc aagaaaatac tagcttcacc caaattgatc atttggatgt
    21841 ctatgatagt tcttatcttt tgtatcgcaa gtggtttttt attatcaaat ttgctatttt
    21901 atagagaaac agaagagact gctgcaaaag aaatactttc ttcgtttagt tccagtggag
    21961 aagatccatc agctgaagga aacgatgtag aagaggatgc tcgtccaaag gtcatgtaca
    22021 ccgatatcaa aggaagtgtg aaggagcctg gtatctattc cttttcttca gaagaacggg
    22081 tctatgatgt actaaagcgt gcaggtggat tattagaaga agcggatagc gatcgaatca
    22141 acttttctgc gaagatagaa gatcagcaag tcctatatat ccctgctgta ggtgaagagc
    22201 tgccagaaca tcttgatcag ttggcatcct cggaaggaaa acagcctaca gcagattccg
    22261 agcctcccaa aataaatatc aatacagcca ctccatcaga acttcagcag attcctggga
    22321 tcggatcagt caaagcgcaa gaaatcattc gatttagaga agaaaacgga tccttccaga
    22381 aagtggaaga cctgcaggag atttctggta tcggtgaaaa gacagttgaa aaactaaaaa
    22441 acttcgttac aattaaatag aatgattcaa aatcgactgg cacgagcaat aaatggacgc
    22501 taatggatac taagaataat ccaattctaa gagcttggca ggacgaggag gtagtatttt
    22561 tggataggaa atagcttgat tgttcgcaaa gaaacattaa aaaaaccaat gctgaatgtc
    22621 tatctccaaa ataaaatatc tgggattcat attatgaata cggctgtcag cggcaataac
    22681 agtcaagctc tacgagaacg ctttgccaaa gatgtactta gctatacagc agataaagta
    22741 tttattctca ttgggacgaa tgatctagca gagcataaac aactttctaa agaaacgtac
    22801 caaaaaatct gcagtggatg atagttcagc tgaaaaaaga ctatagttct gatcatgctt
    22861 tctttatcac gccaccagca gtcgatgaga caaaacaaaa atatcggaat aacaagttga
    22921 tcaaagaata tatctctgtt ctcacagaag tagcaaaacg ccatgattgt gaagtatcga
    22981 tttttatacg gaatttcttg aacaaatgga ttcgaagaat ttttataatg ggctaatgga
    23041 tgacggactt catttcggca gtgaagggta ggatcttttg tcagacagga tgattcgtta
    23101 tatttaaaga atattttgtt taagcaatga gtacttttta atcaacttga aaaaacggag
    23161 gaatataaaa catgttagaa aaatcttcaa aagcatgcga tacgaataaa gaaaaagtta
    23221 ctgataagtc acataatgaa cgcattcctt gggaccagta ctttatggct caggcagtac
    23281 tgttatcttt acgtagtacg tgtacacgtt tagaagtagg agcgacactc gttcgagaaa
    23341 aaaggatcat tgctggcggc tataatggag cagtcagtgg agatgtccac tgcatagatg
    23401 aagggtgtta cgtcgtggat ggacactgct tgcgaacgat ccatgcagag atgaatgcac
    23461 tcctacagtg tgcaaaactt ggtatcccga cggaaggttc agaaatctat gtcacacatt
    23521 ttccatgttt ggcctgtaca aaggctttgt tgcaagctgg tgtgaaaggg atcaattatc
    23581 tccatgacta tcgaaatgat ccttatgccc aagcgttgat cgaacaatta ggtgtatctg
    23641 tacaccaagt tgctttagac tcacagcatt tttcaaaact tcaaaatgaa ttaacaggaa
    23701 aacatgtcta gcgttttaga aaggcatgtt cgaaatcggt tgatttttcc ggcaattacg
    23761 tcgatgatta tctgtttgtt gtattacact gacaattggg gttatcgttt gcttcttgcc
    23821 ggaatttttt tatggttttc gctaaaagaa ggacgtttta tcgcgtactt gtgtattttg
    23881 tgtagcataa cggtatccat ttcttatagg ctacaagagt attcattttt agaggaaaaa
    23941 acaacatctg cgcaaattac tgtatttaca gatacgattc gtgcaaatgg taattttttg
    24001 acaatggaag gaaggttatc agagaataaa caaaagctcc agctttctta tcaagtaaac
    24061 acagaagcag aattgaaaac atggcttaac ttccgaggaa agggaataga attgactgct
    24121 gaaggcgagt tcatctctcc agcaaaaaag cggaatcttt ataattttga ccaagaagct
    24181 tacttcagga accatagaat ttctggacgg ttccaaattc aaaagattga acagatcacc
    24241 atgcaaaatc actggcgaaa ctggcttcag agaaaaagag gatcttttat ctcctttgtc
    24301 caatctgaat ttccgcaaaa aacaagtgta tatattaatt ctttattatg gggctataaa
    24361 gatgcaggat tcagagaacc agaagaaatt tttagggaga gtggtttgct gcatctgttc
    24421 agtctatcgg gtctacacat ccaattttat ttagggtggc tgtattattt atttcgacgt
    24481 atcggatggc cactacacgt cagtattatt ccgttgagtc tactaactat ctgttatgtt
    24541 tctattgcag gaagttctat ttctgttttg cgtgctagtt tgctgttttt attgcgattg
    24601 ctagtcaaat tgctgaataa gcattattcc accatggact tatttgcagt tgtcttttgg
    24661 cttcttttac tatttgatcc tcgatttctt tttcatgcgg gtggacagct tagttttttc
    24721 atgagttttt tgtttatcct gatttctttt gatggagatt ggttgaaaaa aacggcctct
    24781 cacgtcctgt ttactatgat cacgatgccg ttgattgtat ggcattttta tgagtggcct
    24841 attttaggta gtctttttac attactgatt gcaccggtat tcaagtttct ttttcttcct
    24901 ggtgtgttat ttctcacact cttcaatcgc tggctgccgg aaactttact tttgctgata
    24961 gaagagggat taatcttatt tgagcgaata atcgattttt cttcagggtc gtctctcatt
    25021 ataggacgtt tgccccttgt gctatctggg atgtatattt tcggattact gatttgtatg
    25081 gataggttga aagaacaacc tgtgaaacac ttgttttatg ttggtctttt ttcttttatt
    25141 tttttgactt tgccattttt acgcttttct tcaacgatcg cttttatcga tgtcggtcaa
    25201 ggagacagta tctttttgca aagtcctttt cgaaaagaaa cgattttgat cgatactgga
    25261 ggtcagttac actttgaaag agaaaagtgg gcgcaaggta tgatacgtcc tcctgctgaa
    25321 agaaatatcg ttccatatct aaaaggtcag gggataagtg taatcgataa actcatcttg
    25381 acacacgacg atacggatca tgtgggagaa ttacccacgt tatctcagca ttttactatc
    25441 aaaaaaattt atatcggttg gggcgctgga cgaaatgagc cattacaaag gcatttatct
    25501 gaagctcaaa aaaatggtac tgagatcatt gaaatcaaac atggggacag gatcagcggt
    25561 tattatgatc tttatgtatt gactcctttt gaaaagggag agggaagaaa tgaagattcg
    25621 attggtctat ggatggaata taacaatagg cgctttttat ttttaggaga tttgaatcaa
    25681 gcaatggaaa aacaattgct tttgatttat cctaatctga aagccgatgt agtcaaatta
    25741 ggtcatcacg gtagccgtac gtcaagtaac acagattttc tttcccatat tgaagcaaaa
    25801 catgggatta tatcctgcgg cgtaaataat cgttatggtc acccgcacag cgaagtattg
    25861 gagacactag aagaaaatca gataaaaaca tggcgaacgg atcaacaagg aatgatcacc
    25921 tatcgctggc atccagtttt tcatcctcat gggctagtgg aaacaatgat agactagtaa
    25981 ttctcatctg ctcatggtag gataattttt gaaagtggtg agtaatttga gtatacaagc
    26041 agagttacaa aaaatacgta aagaaaaact tgcatcttgt tacttgattt taggaacaga
    26101 aaagtttctc caagatcaag ttcggacaga aattgtcaaa aaaatccaat tagagggcga
    26161 agatgactta aattttttaa gttttgacat ggaaaatgca agtttagatg aggtagtagc
    26221 tgaagcagag acgttgccgt ttttcggaga tcaacggtta gtattcgtag agaatcctta
    26281 ttttttaaca ggtgaaaaag taaacaatgg aatcgaacaa aatactgatt tattgacggc
    26341 ttatttgaaa gaaccattag aatcgactgt attagtattc tttgcgccat atgaaaagtt
    26401 ggatgaacgg aaaaaagtaa cgaaacaatt gaaaaaaaca gcaattatca tcaatgtcca
    26461 acagttgaat gaaaaagaag tacgtcaata tctgatgaat accttagaga attcctcaat
    26521 caaaatggaa cgaagtgcaa ttgatttatt cttgaggttg accgacttag atttatccaa
    26581 aatgatgaga gagttacaga aattggtcct ttatggacaa aatcaacagc aaatcacggt
    26641 aagagaagta gaagaattag ttcctaaaac gttagaacat aatatttttg acatgaccca
    26701 atatatttta aaagggaaga cggaacaagc tttgcgttta tacgaagatt tagttatgca
    26761 aggggaagaa acaatcaaaa ttaatgcgat tttgctttct caattacgtt tatttttaca
    26821 gacaaaattt cttgtaaaga ttggttatca gcaggcaaat attgctgaaa cattgaaaat
    26881 ccatccatat cgtgtaaaac ttgccatgca ggaagtaaaa aaattcgatg aacatttgct
    26941 ggtacagttg tttgatcaat tagttgagat ggattatcaa atcaaaacgg gacaaatcga
    27001 aaaagaatta agttttcaac tattcgtttt gcgcacaggg cagttgttaa gaaatcgata
    27061 agaagaaaga cgagggcaaa gcatgcggga aggtcgtttg tttttgtcct ttttttgaca
    27121 aataaaaaaa tcggccgaag ccgattcttt tatttagcga tttttttgct taaacgagat
    27181 ttgtcgcggt tagctttgtt tttgtggatt agaccttttg attcagccat atcaatagct
    27241 ttaacagctt ctttatataa cgcatctacg ttgtcagcac ctgaagctac agcatcttca
    27301 aattttttga ttgcagtacg catagcgctt gtttgagatg aatttttcac attagcgttt
    27361 tcgcttgtac gaacacgttt gattgcagat tcaatgtttg gcattagttt cacctccgat
    27421 aacttaagtt cttacgcgtg ttaccgcata attcaacatt cattattata cctaaaggca
    27481 gcgtgctttg caatatgaac atgacaagtt tttttcctta acagtctttt attaggattt
    27541 tttttcagta aaaacggata gtacaagctg aaaaaaatca aaaagacgct attgtgggag
    27601 gcaatagcgt caaaccaaac tagattttta tttatctatt taaacaaagt ttgaatggga
    27661 atgtttggta ctaagttatt atataacaaa gagaaccgtt tgcaaagttt tttttgaaaa
    27721 gggatacgat tccctgttgt tctttgtttt tctattaaga aactgcagtt attttataac
    27781 cagtatcctt tgatcagtaa aggctattct ggtgtaccga ttattttaat gtattcatcg
    27841 atatttttta tcaacatttt ttttatgacc aactggttcc gacggttcca tttgccactt
    27901 acttccagca catatttatt taggggcaaa cgtaagatat attttgccaa atagcgatct
    27961 ttaagcaggc cattgatcac acggtcctca agctgcaagt tgatcccagt cagcatcatt
    28021 ggctgttctt gtaaaacgta cgtatcaatt aaaagacctt caaaagtttc cacaagcgtc
    28081 ttcctttctt ttcaaagtaa cctgaaaaca ggcactaatt cttccatttt gatattcgtt
    28141 gaagtggatg cgatcattct ttcttttgtc cactgtaatc tagtataaca aaaaagagca
    28201 gaagagccaa aaagaaaaaa gagcatcgaa ttctatagga agtctcattg gcacggccta
    28261 aattattaca
//
LOCUS       DAXLPY010000029        28196 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.029, whole genome shotgun sequence.
ACCESSION   DAXLPY010000029 DAXLPY010000000
VERSION     DAXLPY010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.029"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..416
                     /locus_tag="ACF3UF_001405"
     CDS             <1..416
                     /locus_tag="ACF3UF_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3671546.1"
                     /translation="VCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLVLWEKKKTSV
                     KELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAALQKQAEGIP
                     QKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            525..1604
                     /locus_tag="ACF3UF_001406"
     CDS             525..1604
                     /locus_tag="ACF3UF_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3671547.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(1730..3019)
                     /locus_tag="ACF3UF_001407"
     CDS             complement(1730..3019)
                     /locus_tag="ACF3UF_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3671548.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEVAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            3167..4720
                     /locus_tag="ACF3UF_001408"
     CDS             3167..4720
                     /locus_tag="ACF3UF_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3671549.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            complement(4828..5910)
                     /gene="uxuA"
                     /locus_tag="ACF3UF_001409"
     CDS             complement(4828..5910)
                     /gene="uxuA"
                     /locus_tag="ACF3UF_001409"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFD3671550.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5901..7547)
                     /locus_tag="ACF3UF_001410"
     CDS             complement(5901..7547)
                     /locus_tag="ACF3UF_001410"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFD3671551.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            7731..8393
                     /locus_tag="ACF3UF_001411"
     CDS             7731..8393
                     /locus_tag="ACF3UF_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3671552.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8537..9100
                     /gene="ahpC"
                     /locus_tag="ACF3UF_001412"
     CDS             8537..9100
                     /gene="ahpC"
                     /locus_tag="ACF3UF_001412"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFD3671553.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            9110..10639
                     /gene="ahpF"
                     /locus_tag="ACF3UF_001413"
     CDS             9110..10639
                     /gene="ahpF"
                     /locus_tag="ACF3UF_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFD3671554.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            10796..11146
                     /locus_tag="ACF3UF_001414"
     CDS             10796..11146
                     /locus_tag="ACF3UF_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFD3671555.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            11245..11775
                     /locus_tag="ACF3UF_001415"
     CDS             11245..11775
                     /locus_tag="ACF3UF_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFD3671556.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            11929..13080
                     /locus_tag="ACF3UF_001416"
     CDS             11929..13080
                     /locus_tag="ACF3UF_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFD3671557.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(13189..15228)
                     /locus_tag="ACF3UF_001417"
     CDS             complement(13189..15228)
                     /locus_tag="ACF3UF_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFD3671558.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIPDKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(15286..15843)
                     /locus_tag="ACF3UF_001418"
                     /pseudo
     CDS             complement(15286..15843)
                     /locus_tag="ACF3UF_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     regulatory      complement(15991..16157)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            complement(16382..16588)
                     /locus_tag="ACF3UF_001419"
     CDS             complement(16382..16588)
                     /locus_tag="ACF3UF_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671559.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(16604..17218)
                     /locus_tag="ACF3UF_001420"
     CDS             complement(16604..17218)
                     /locus_tag="ACF3UF_001420"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFD3671560.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(17365..18048)
                     /locus_tag="ACF3UF_001421"
     CDS             complement(17365..18048)
                     /locus_tag="ACF3UF_001421"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFD3671561.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(18157..18615)
                     /locus_tag="ACF3UF_001422"
     CDS             complement(18157..18615)
                     /locus_tag="ACF3UF_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFD3671562.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(18699..20462)
                     /locus_tag="ACF3UF_001423"
     CDS             complement(18699..20462)
                     /locus_tag="ACF3UF_001423"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFD3671563.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(20683..22143)
                     /locus_tag="ACF3UF_001424"
     CDS             complement(20683..22143)
                     /locus_tag="ACF3UF_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671564.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(22351..23277)
                     /gene="glsA"
                     /locus_tag="ACF3UF_001425"
     CDS             complement(22351..23277)
                     /gene="glsA"
                     /locus_tag="ACF3UF_001425"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFD3671565.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(23300..24727)
                     /locus_tag="ACF3UF_001426"
     CDS             complement(23300..24727)
                     /locus_tag="ACF3UF_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3671566.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(24758..25972)
                     /locus_tag="ACF3UF_001427"
     CDS             complement(24758..25972)
                     /locus_tag="ACF3UF_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFD3671567.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(26058..26285)
                     /locus_tag="ACF3UF_001428"
     CDS             complement(26058..26285)
                     /locus_tag="ACF3UF_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671568.1"
                     /translation="MKNKFENRSDTRCGSFLYILYEVFFIPYEKISLKIKKDENKRFS
                     IKRRPFIFCLYLCEKRKRAQHIKLLLIVCLL"
     gene            complement(26313..26555)
                     /locus_tag="ACF3UF_001429"
     CDS             complement(26313..26555)
                     /locus_tag="ACF3UF_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3671569.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(26587..27144)
                     /locus_tag="ACF3UF_001430"
     CDS             complement(26587..27144)
                     /locus_tag="ACF3UF_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3671570.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(27157..27345)
                     /locus_tag="ACF3UF_001431"
     CDS             complement(27157..27345)
                     /locus_tag="ACF3UF_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFD3671571.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(27358..27924)
                     /gene="amaP"
                     /locus_tag="ACF3UF_001432"
     CDS             complement(27358..27924)
                     /gene="amaP"
                     /locus_tag="ACF3UF_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFD3671572.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         8177 a         5451 c         4936 g         9632 t
ORIGIN      
        1 aagtatgttt tcctttatat gccgcctcta aggaaatcat tagacactac acttccctcc
       61 tcaagccgct gaatcttacc tatacccagt atcttgtgat gttagtttta tgggaaaaga
      121 aaaagacttc agtgaaagag ctaggaaatg atttgtgtct ggattctggt acgctgactc
      181 ccttactaaa aaagttagca gaaaaaaatt atattaatcg tcagcgtgaa acgggtgatg
      241 aaagaatcgt aaatgttacg ctgactcctc aaggtgctgc gttgcaaaaa caagcagaag
      301 gtattccaca aaagatcaag tcttatcttc cacttgaaca ggaagaattg gatacactgc
      361 aacatctgac ccgaaaaatg ctagataatt ttcatcaaga ccagaaaaag ggctgaaact
      421 gctagatgaa cgattttatg aggaaaacca actcataaga taacgtcatt tagcggtttt
      481 tctttttgct ctttctcttt cttattttca tattccatca tataatgaat aacgtgttta
      541 ttttttgtta tttggaggtt gtcgatttga ccgtttatca gcgttttttg gcgaatgaaa
      601 aaatacgccg tctcactgtt ttattatttg tcgtttttgt tcttttctta gttagaagta
      661 tgattacaac cattttgctc acatttatct ttacttattt gatgattcat cttgttcaaa
      721 tcattcagcg atttgtccga atccctacag gtgttttagc tatcatgatt tatacactga
      781 tcgtttacct tatctatctg gcattcacaa agtatatccc gatgcttatt catcaaacat
      841 ttgatatgat ccagtccgtt attgattttt acgagcatca gccaaaagat gcagatcctg
      901 ttttacaata tatccatact tatattgagc gaaacgattt ttttgaacag cttcaaaatg
      961 gcgcttcgat tgcgcttggc tatttacagg atataggaaa aatggcagtg gcgtttgcta
     1021 tgtcattcat cttaagtttc ttttttatga ttgaaaagaa aaaaacaatt gtattctcaa
     1081 gattgttttt aaaaagtgaa ttttcttggt tctttcaaga tatttactat tttgccgata
     1141 agtttgtcaa tacatttggt ttggtattag aagctcaatt tgttatcgct cttttaaaca
     1201 cgttgctcac tacaatcgcc ttggctgtat ttggctttca tcagctgctg agtttagcga
     1261 tcatgatttt cattttaagt ctgatcccag tagcaggtgt tatcatttct tgtattcctc
     1321 tatctttcat agcttattcc caaggaggca tccgagatgt tgtttatatc ctgattacga
     1381 ttttgattgt ccatctaatt gagtcttatg tgctgaatcc gaagttgatg tccagcaaaa
     1441 cagaactgcc gattttttat acatttgtgg tcttacttgt tagcgaacgg ttctttggcg
     1501 tttggggctt gattgtcggc attccgatct ttaccttctt tttagatgta ttgaaagtga
     1561 aaaagatccc gaaccatctt ccaaaagaaa cagatatccc ttaaaataaa tatgaagaaa
     1621 gataaagtat gaacgacccc aaatatcaga tttcaatctg gtattttggg gtcgttttct
     1681 ggatatttct ttttatttga aaaatgcgtt cacagacatt attcaaatgt tagagagatc
     1741 tgttttgttt aaatcttttt gcagaaagca ttgttgctat acttaataga atgattccgc
     1801 tccacagtat aactttgttt tgtgactctc cggattttgg tagctgttta tttttcgttt
     1861 caggactagc aaaggttgta tccttgctac tttttaaggt ttcagctgat tgggcgctat
     1921 caaatattcg tgatttttta ttcagctgct cttcatttat ttttagaatt gctagatttg
     1981 attttttact ctcttttttt ccatcctctt gaattgtttt tttgtttatt ttttctggta
     2041 ttccttggtc tcttgcgtcc gtatctggtt ctggagtcac atctggtttt tcttctggat
     2101 ctacctctag tttttctgga ttttcagttt cattatctgt gtctggattt gtttccggta
     2161 ctgtttggtt tccagaatcc gtatctggtt ctggagttac atctggtttt tcttctgggg
     2221 ctacctctgg tttttctgga ttttcagttt cattatctgt gtctggattt gtttccggta
     2281 ctgtttggtt tccagaatcc gtatctggtt ctggagtcac atccggtttt tcttctgggt
     2341 ctacatctgg tttttctcca ggggttattt caggttttga ttcattgtct ggctctggtt
     2401 gagtttctgt atcgggttct tctccaggtt ctatttccgg tttctgttct ccgtctggat
     2461 tttctgtagg cggtacttct ggcttatttt cattttctgg tttatctgtt ggttcttcaa
     2521 caagatctcc tcctgagtcg atagctgaat cttgctcaat tgtctgccgc tgactatacg
     2581 gcgttaaatg atgatgatcg ttcggtagtc catctgatac cttgacagta aaaagcgctg
     2641 gttttaacaa gtcctgattt aatgtaacgg tgaaggtaaa tatcgcttgc ttgtgttgga
     2701 tagtcaaagt gttctcgtca tagccaatcg acaaagcggg atcaacattc tcaaatgtaa
     2761 cagctgattg tagtataggt gctaagtctc ctgaatagtc aatttttgct ttgatggtcg
     2821 ctgtttgtcc ttttcttaat tttgcgactc ctgaattgaa ggatgaaaat tcatcctgaa
     2881 aggtaattcg attgacgttg gcccacttgg tttctgtcca tttggctgtt tctatctcct
     2941 ctgtgtggac tgtctgattt atagtaagcg ataagcttaa ggctgcaaat gttgatatta
     3001 agatggttga atatctcata actctctcac tccttgattt ttttgtatgc aagaaataag
     3061 atagtagaga ttctacctat atgtttactg tttttttgtc taaatttatg aaaaaaacag
     3121 taatattttc aagttttaac aatttaagta aaaaggagcc tctttcatgc aaactcaaga
     3181 agcgattaaa acgtttctct tgaagaaaaa aagcaataca aaattagata tttttctttt
     3241 cctatctgaa catcgtttct ttattactac acaatattta gcagatcatt tccatatgtc
     3301 tgaatcaaat tttttactat acatcaaaga attagaacaa gactttgagc gtctcaatct
     3361 aacagaactg catattgata agcaaaaacc ttttttaaag ttgaattttg aaggaattga
     3421 tccggcttac tgctattatc gtctatttgg aagatactgc aacgaatcag tcagttatca
     3481 gatcttgact tctttgttca gctgtcagac aaattcgatt atcagtttaa gtcagcaaac
     3541 aaactatagt gcctcttatt tgtatacgaa aatgaaaaag attaatgcat ttttagcatt
     3601 gtacggtttg tctatctcct tttctaataa tggcagaaag tctttttctg gaaaagaggt
     3661 acaaattcaa tatgcagcat tagatattta ttggaacatc ttttcaagta ctgctacaga
     3721 attttatgat gaagatccgc aagtagtggc ttttatgatg aatacttttt ttaaaaaaga
     3781 agtacttgac cgactaaata gcggtatgat agataaatta tattttctat taaaaatatg
     3841 taaagagaat tttcctgcaa cttctgtgaa agacgtacaa aaagaattca cagagtatga
     3901 atatattgac ttttttattg atccctctgt agatattttg cgacctaatc tgccaatttg
     3961 tcgcgaacaa cgcatcttag tgaatatttt agctcgactt tctatcacga aaatcgaatc
     4021 ggaagaaaca agcttggagc aatacaaact tttaaaaaaa gcaaacgttc ctcatgttct
     4081 ttattcaaga gaaatggtgg agtccttttg tactgtattt gatttgttta tacctgaaaa
     4141 agaaaagatt ctttactcat tggcattcgc acgaaataaa ctttataatg gatttcttaa
     4201 cttcaatcaa ccaaatacgc cccttcctac tttcatgctt tatcaagaac atagcgtgtt
     4261 gaaagaagtc caaaccgcca ttgaacaatt ttatatggat ttcagagaac aaaatcaaca
     4321 cttgttacca gttattttag aaaaggaaaa tgtgcaatgg atggttgaag acctagtaca
     4381 tttgtatgat cgctacaaaa aacagccgcg aattgtgatt ggtgtgaact atacgcgtga
     4441 tttttatatc agtaaagatc tgatcgttaa gatagaacaa attttttcaa atgaatcgat
     4501 caaaatacaa aatgatttta tggagaactg caacatcgtt atcagcgact gccctttgaa
     4561 acaattgcct tctcatatca aaaaaatcta tattttaaaa ggaatcatca caccagaaga
     4621 ctggaaaaaa gtgattatga ggatctcaga atatatcttt gaattaaaag aagaagcact
     4681 catggatcaa tcgaaaaaag aaaatcaagt tacttcctag accaaataag atacataaat
     4741 ccgaatgctt attaacaacc tccggattta tgtatcaaga atttgaacat ccttcttatt
     4801 tacataataa aattacagtt tttttcacta attatcttta cttttgtttc ctttttcgat
     4861 tgcttcccat aatccattta gataaacagc acctaatgct cgatcatata agccgtatcc
     4921 tggtcttcct gtctcattcc agatcattct tccatgatca ggacggatgt atccgttaaa
     4981 tccgttgtca tacattgttt ttagtatgcg gtacatgtct aatgaaccgt attcggattt
     5041 atgcggtgcc tcatagaaat ctcgattagc taaaaattta atatttcgaa catgtgcaaa
     5101 tgggattcga tctctttgac aaaattctgc taaaatccca tatacatcat tttctggatc
     5161 ttctgcaata ctccctgtac aaagagtgat tccgttataa gggctgtcta ctatgcggca
     5221 caaccaatct aaatcttctc gattctttac gattcgaggt aatccaaaaa tcgagtatgg
     5281 cggatcatct ggatgtacag ccattttgac ccctacctct tcacatgttg ggatgattga
     5341 ttggagaaaa taggcaaaat tttctcgaag tttttcttcg tctactgatg cataggcttc
     5401 aagcaaggat ttgatatgag ctaagcgctc aggttcccat cccggcaatt caaattcatt
     5461 gctggaatgt tcgatgcgcg cgacgatttc tcttggatca tctggaatat catcagatat
     5521 aaaagctaac gtggatgagc cgtcttctaa gcggtagtca aggtcagatt tcacccagtc
     5581 aaatacaggc ataaaattat agcagatgac ttctattcca tattctgcca agtttcggat
     5641 tgtctgctta tagttttcga tatactgctc acgggaaggt aatccaattt taatggcatc
     5701 atgcacattg acgctttcaa ttacttttag tgttaaccca cgagactcaa tttcttcttt
     5761 tagttctttg atcctctccc taggccatac ctctcctact ggtatatcca tcaatgtgcc
     5821 tacaatccct ttgaccgcag gaatctgtct gatttcatct aaggtaatct tttcttcctg
     5881 tgatccgtac catctaaaag tcatttccat gataaatttc ctccatgttc ttgtaagtaa
     5941 tcctgtaatg tttttcgtac ggcattcggt cctgctacca tcttgatgaa catttcttct
     6001 atttttctgc caagctctgc ttggtaaaga tctacaccaa aaatttcttt atttgacaaa
     6061 ataggagcca ttttctcatg aatatgtgat gtatcttgcg tacccagttg aatatcggaa
     6121 agcttatgct gaaagtctgt caatagtggg tctggactcg ggatgaatgg ttttccttga
     6181 tcatcaatgc caataaggta tcgaagccaa gcagcgagag tcaatggtat gaatacaagt
     6241 gtctgcgggt ctttaacttc tatttccata tattttttaa tcgtctcacc ataacgaatc
     6301 gccacctttt gagaggtatc cgtggcgatt cgctgaggca tatcaggaat atttggatta
     6361 gaaaagcgca cagtaattac ttcttccaga aagatctttg gatcaatgat acctggagac
     6421 tccacaactg ggaggccttc attgtacccg atttcagaaa ctagcagcga taaatctgga
     6481 tctttcatct cctcagctat gctcctatac cccagtaaac aacccataat agctaaagac
     6541 gtatgcaaag gattaaggca agtcgtcacc ttcatcgtat ctgctttatc taccgttgca
     6601 cgatcagtca agaatacccc agctttttcg aatttcggac gtccattggg aaaatgatct
     6661 tccatgatta aataatggat gtcctctgta ttgacaaatg gagcaatatt atttcctttt
     6721 gcggtttgga aaatcgacat atttgaaaag ccctcttttg ccaacatttt gctaactgac
     6781 aaggaaggat tcggggtgat acgatcaatc atcgtccatg gaaacgcaac aatttcttca
     6841 ttcgataagt attggataaa tgtattttgt acataacctt ccttttgcca ttcttttgcg
     6901 atcgttagca aagaagtacg taattgacta ccgttttgtg aaaaattatc tgtagagaca
     6961 agtgcaatcg gccaagctcc agataaaaaa cgtttataaa gtagcgcagc aagaatactc
     7021 attgtatgtg atggcttctt tggaccattt tttatatcga ctgcaatcgg tcctatatat
     7081 ttattatttg tatctttcaa tcgataacct ttttcagtaa tagcaaaagt aactaattgt
     7141 aaactaggat tttcaaagtg tcgaatcatc ttatcaaagt gttcagaaca atctggatga
     7201 caatacagac tgtcagctgt cgcagctaat atacgtttga cgaactctcc actgcttggc
     7261 atgaccactt caagaatcaa atcatcaaaa tcttggtaag ccctttcaat tatttcttca
     7321 tcgaatgttt cacaaacaat gacaccagtg gacaattcgc ctagatccgc taaacgttga
     7381 gcgatttctg catgaaatcc tcgataaaga tttccgccac cgaaatggat ccagacagga
     7441 tttttttgtc cattttctct taatgatgca cggtcaaaat gaggtatttc tacttctttt
     7501 tgagataatt cagggataaa gttcctccag ttgtttaaat caatcatttt tcccctccta
     7561 aactaacata ttagtttttg tattcaagtg aattttatac aataaaaatc gctatgtcaa
     7621 ccaaaatttt actatttata caaatttact agttaatgtg acataccaga ttgtttttca
     7681 gacctcttct gttatactac gttcatagaa atgattttgg aggaataaag atgaaaagca
     7741 gcttgcaatc acaagcttat caagcgattc gtaaacaaat tatctatgct gacttagaac
     7801 ctggaaggaa aatatctgaa aaggcactgg aggaacatct tgctatcggc cggactccca
     7861 ttcgcgaagc attgattcaa ctacgtcagc aagaactcgt gtatacgata cctcaaagtg
     7921 gtacgtatgt ttccaaaatt aatcttgttt ctgcagaaaa tgctcgcttt gtccgagaac
     7981 agttggaaga gcaaatcatg attgaatgtt gttccaaatt ggacacacaa acacgaatag
     8041 tgctagaaac gattttagaa gaacaagaaa aagcagtcaa aataaatgac gaacgcgctt
     8101 ttttccgtgc agataattta tttcatgaag cttgtttcga aattgcagga agaaaagaag
     8161 tttggaactg gttagatgac cataataccc atttagaacg tttccgctgg ttacgagtga
     8221 ccattcaggg gcttccatgg gaaacgatca tggaacaaca ttatgattta ctcaaggctt
     8281 tagttgataa aaaaccagaa gaagctcgat ttcaaacggg attgcactta cacatgatgc
     8341 tgaaagaaca ggaaactgtt actcaacgtt atcccgagta tttccagcag tagcattttc
     8401 ttgcgacctc ttctattttt ataattaacc ttcgtttttg agtaatcttt attaaataac
     8461 aaaatatcca ttgactttgc aactccaact aaattacaat aattataaat aaataattat
     8521 tattggaggt tttactatgt cattgattgg gaaaaaaatc gaagaattta atgcacatgc
     8581 ttatcatcaa ggagaatttt tagaagtcag tgaaaaagat cttatgggga actggagtat
     8641 tctttgcttc tatccagctg attttacttt tgtttgtcct actgaattag aagacttaca
     8701 agaacaatac agtacattga aatctttagg tgttgaagtc ttttcttgct ctaccgatac
     8761 ccactttact cacaaagcat ggcatgatac atcagatgct atcggtaaaa tcgaatacgt
     8821 gatgatcggt gatccgtctc atcagatttc tcgtattttt gatgttttgg atgaagagca
     8881 aggattagct cagcgaggaa catttattat tgatccagac ggaatcgttc aagctatgga
     8941 aatcaatgca gatggaatcg gtcgtgacgc tagtgcactg attgataaga ttcgcgctgc
     9001 tcaatatgta cgtacccacc caggtgaagt ttgtccggca aaatggaaag aaagtggcga
     9061 aacattgaaa ccaagttttg atcttgttgg aaagatttag gtggtggata tgttagacaa
     9121 agaaactaaa caaaatctcg aacaatattt agcactgatt gaatctccta ttgttttttc
     9181 tgttagtttg gataatagtg aaaatagtca aaaactagct gaatttacga aggaaatagc
     9241 agaaatgtct cctaaaatct cttgggaaaa aagagattcg atgcgcacac ctagtttttc
     9301 tatcaatcca gttggcaaag aaagtggaat cgtttttgct ggtatccccc tcggtcatga
     9361 attttcctct tttttactgg ctatgttaca aattagtgga cgggcaccga aaatcagtga
     9421 atctttgagt cttaaaatca aaaaaataac acaaacattg cattttgaca gttatgttag
     9481 cttgacttgt cataattgcc ccgacgttgt acaggcattg aatatattag ctgtattaaa
     9541 tccaaatatt actcatacga tgattgaagg tgggatgttc caaaaagaaa tcgatgataa
     9601 aaaaatcatg gcagtgccaa ctgtgttttt aaatggagaa gaatttagta gcggacgcat
     9661 gacgatcgaa caaattgttg aaaaaatcac tggccctttg attgaagaag agttgtttga
     9721 aaaagaacct tatgatgtat tagtaattgg cggtggacca gcagctagta gtgcagctat
     9781 ctatgcagca cgtaaaggaa tccgtacagg acttgtcgct gattctttcg gcggacaagt
     9841 cgttgaaaca ctagggattg aaaatatgat tggtacctct tacacagaag gtccaaaatt
     9901 gatgcagcaa gtagaaagtc atgtgcgtag ttaccctatc gacattatga tgaatcaaca
     9961 ggccgtttcc ttaaataaag agcaacattt tattaatatt ggcttagcta acggtatatc
    10021 acttaaagca aaaaccgcca tcatcgcgac aggtgcgcac tggcgttcta tcaatgtacc
    10081 aggcgaaaaa gagtttaaaa ataaaggaat tgcttattgc ccacactgtg acggcccttt
    10141 atttaaagga aaagagattg ctgttatcgg tggtggtaat tctggtgttg aagcagcaat
    10201 cgatttggct gggttagcaa aacatgtata tgttctagaa ttcttaccag aattaaaagc
    10261 agatcaaatc ttacaggata aactagtctc tcttgcgaat gtcactgtta tcaaacatgc
    10321 agcgacgaaa gaaatcagcg gtacgaatca ggtagaatct ctctcctata tcgatcgccg
    10381 tacgatggag atgcatacac tagctgtttc aggagtattc attctagtcg gcttactccc
    10441 taatacggat tggctagatg gaacgatcga aatgaatcca agaaatgaaa tagtgaccga
    10501 gaaaaatggc gcaacgaata tccccggcgt tttcgcagct ggtgattgta cagatagtcc
    10561 atacaaacaa atcattgttt caatgggttc aggagctact gcagctttag gagcattcga
    10621 ttatctgatg cgcacttgag ctatgaagat tgtaaaaagt cagagagcgg aaaaaaggat
    10681 ggtgacaaga attttgtcac aatccttttt gtttttttga ataatcgctt tttcttctct
    10741 ttttcttata tactataagt agtaaataat ttgaaaaaaa gaaaggtgac tgattatggc
    10801 gcaaaatcgt atttttacga caagttttgc aagcgtttat cctatgtatg tagcaaaagc
    10861 ggagagaaaa gatcgtataa aagaggaagt agatgaaatc atttgttggc tgacgggtta
    10921 ttcccaaaca gaactagaat atcaactaca aaaacaagtg actttcgaac aattttttgc
    10981 ggaagcccct gtccccaatc cttcacgttc cttgattaca ggtgttgttt gtggtgtacg
    11041 agtagaagac atcgaggata acttgatgaa agaaattcgt tatttagata aaatgatcga
    11101 tgagctagca aaaggcaaaa aaatggaaaa gatcctcaga agttgatttt tccagagata
    11161 ttcttctcct tcgctcattt tgtaacattt aatttggtaa aatgactagt tcacgttaaa
    11221 ataagtcaaa ggaggttttc ttatatgttt gagacgatta aacaaaatat tcaaaaatac
    11281 gccttattaa gagctgctgt ttatattatt tctgggattg cgattgtgct aaacccttct
    11341 gctgtttttc attttatcgg ttatctgatc accgcctatc ttgttttgct tgggttgttg
    11401 aatctttttg aggcttaccg ttttaaaagg aaaacaggtt cttggagtat cggtctgttc
    11461 agtggtcttt ttttcctgat cttagctctg atcgtctatg cttttgcacc tgcaatcgtt
    11521 tctatcctgc cgattcttct tggattagct gttatcatca acagcttgtt ccagttgttc
    11581 ttcagcatga atacaaaagc taaaagttgg agtgtttata gtagtattct gttgttgatt
    11641 ggcggattcg tcttattgtt caatccattc aaaagtttga tgcttctatt ccaaatattc
    11701 ggctttattt tgattttcat gggcatccag gagattatca atttcatcag aataagaaaa
    11761 atgactatac gttaatcatt tttagttatt aaaatagacc gtataaaaac caacaatcca
    11821 aaaaaatctt ttggattgtt ggtttttttg tgagtatatt ttcctatttt ttcaataatg
    11881 tatgttatgc taagttcggg ctatatttta tacaaaggaa tgatgagaat ggaatttatt
    11941 ggtattttat gcctgatatt gatttcaaca acgattggct cacatatctc gcggagatta
    12001 ggtatcccag cagtgattgg acaattactt gttggtgttt tgctaggcca agctggattg
    12061 aattgggtca aacctgatat tctagtccat gacttttcgg agattggtgt gatcttatta
    12121 atgtttttag ctggtctgga aagtgattta tctcttttga aaaaatattt ccgacctggt
    12181 atgttcgttg ctttgcttgg gatcatcttc ccggttgttt ttggctggtt gacaggcaaa
    12241 gcattccaag tttcgggaaa tgaagcgatt ttctttggga ttattcttgc ggcaacttct
    12301 gtcagtattt cagtagaagt attaaaagaa ctaaacgtag tgaatacaaa agaaggatca
    12361 acaattttgg gtgcttctgt ggtagatgac attttagtcg ttttagttct aagtttcagc
    12421 ctatcttttc taacggggga agcttctagc aatgcttctt taccgcttgt tttgattgaa
    12481 cagctaattt attttgtttt tattttctta ttagtcaaat ggattgcgcc tttcctactt
    12541 tcatttgcag aaaaagtgta cgcaaattct tctattatca tcgtatcgct agttatttgt
    12601 ttaggaatgt cttacgtagc ggatcttgtt gggcttagct ctgtcattgg tgcttttttt
    12661 gctgggatag ctgtcagtca gacaaaggtt aaagaagaag tataccacaa tgtagaggct
    12721 ttaggatatg cagtatttat accagtattt tttgtcagtg taggattaga agttgatttt
    12781 tctgacttta gtgaacaact actctttatt tctatattga cgcttgtagc gattttgacc
    12841 aaattgcttg gaggttattt tggtgctcag attgccggtt tttctcaaca tagttcattg
    12901 atggtcggtg ctggtatgat ttcgcgtgga gaaatggctt tgatcatttt acaaattgga
    12961 cagcaaagtc aattgatcga accacagtac tattcacctt tagttatcgt gattttatta
    13021 agtacactta tttctccact tgttctcaaa tattttacaa aaaaagttta tgaagtgtga
    13081 gtaaatcaaa aagaagttgt gaaagagaca tcgtgaaaac cgtttatttg aaaaaaggac
    13141 tgtgacgata acgccacagt ccttttactg tacttaaaaa gcaatttttt attgataatt
    13201 ttggttgagg tattgcaata gttccgatgc tcgtttggtt gctgaatcat catcttcttt
    13261 attttccaac atgctgacca tcatataacc ttggttatca agattgaaag caaacaagaa
    13321 actgttctct tgccccttta catcctgttt ttctttgatt tccgctgtac cagttttcgc
    13381 tgccaacgga atccctaaag cagaaagaga atgtgctgta ccatttacat cttgcacaac
    13441 ttctctcaga tctggcacga tcgtttgtac tgctgtttcg ctgatgacat tcttcttatc
    13501 ttttgtctct ttatctggaa tcaatttagg atagacaagt gtgccattgt tggtaaaaac
    13561 agaatacatt gctgcttgct ggataggagt aattagaagt tcgccctgtc catatccagt
    13621 atcagctagc aagatatctg agttaaagct atcttcatta gaaatttgtg ctggattcat
    13681 actaattggc aaatcaaggt cttcaccaaa aatgaattta tctaagcctg tacgaaattt
    13741 tttctcaccc attttcaacg tttcttgtgc cgcatatata ttatcggaat agatcaaagc
    13801 agtttttaag tctacttgtg atacatcact actgacacgc gttgttttaa aagatcccca
    13861 agaactgtct ttttgccatt taagcccgtt gatcgtcaac acttcatttg gatcgatagt
    13921 gccgttgtcg agaccgattg ctgctgtaat cattttaaac gtagatccag gagcataacc
    13981 tgtcgcaaat cggctgatga atggatgttc aggattttct tcataagctt tgtaatcttc
    14041 ttgtgagatc ccgtttgtca ttttgtttgg atcatagctt ggagagctag caagcgcaag
    14101 aagatcaccg gtttttggcg ttgtcgcaac agttgatgca gcttttcctc ctagactgtc
    14161 aaaagctatt ttttgtgcct tcgcatcgat tgtcaatttg atatctttgc cattttgaac
    14221 ttcatgttcg atcagaactt ttttctctac accgtctgca tctgtaatgc ttaatttccc
    14281 acctgttgtc ccacgaagat ccttatcaaa agccatctcc aaacctgagc gaccgatttt
    14341 tccattactg cttaattctg gattcttatc aatatcttct gctgtgatat ctcccacgta
    14401 accaatcagc tgagcagctg cttcacccaa aggataatat ctgccgtcta cttcttgaat
    14461 ggtagctcca gctggaagtt ctggcgttgc tccatcaatg attttcaatg ggacaaagta
    14521 atcgggttgt acccagcttt gtgaaatcgc ctgattgata gcatcttctg ttaagtcgaa
    14581 ggaggaagca atcgctttga tattggctgt tttttcgcct ccatctccaa gtttacttgg
    14641 aacgactcct aattgtttta gtttgcctgt tgttgctaat ggttcaccat ttcgatctat
    14701 aatattccct cttgctgctt cttgtgtggt caggcttact ttgtcatttc cttccatttc
    14761 tggaaaaacc aagttgggtt gccagttgat cgtggtttga ccatcatttc tgtctaatgt
    14821 tcctttataa gaaagatctt tcaattcacc taatgaggta ttcatctttg ctttatatga
    14881 aaaactgtaa gtagaatcgt cttttttatc tacttttaga ttcgatatct gaagtccttt
    14941 gacatcagca gcaccgtata tattctggta tttatctaag atctcttttt cagataatgc
    15001 acttttattt gccgcctttt ttgatgtcat ttctgcagct ttgttataat ctcccttgtt
    15061 caaagcttgg acaaattgct caactgtctt ttctccagct tctactgctt gggtttcttg
    15121 atagtgctgg tagtaaaaat aaccgccacc cgcagctgct attaagatca ctgcgccggc
    15181 aatataagcg cctgttcgat ttttgccgtg cttgtcactt cttttcattt tttcctcctt
    15241 ctcttgcttg tcattccttt atttcactat ttatacctgt ttattctaac atatgtcttt
    15301 gaggaaatcc ataccacaat ccagaagcac actttctgga aggttcgttt ggatactacc
    15361 aagtaatttc ccaaccgctt tgggtagctt gaatattgaa gttacgtctt tcagctgctg
    15421 agagatagct ttgatcactt gctgctgcct tctgatcctc ccgaagtctc cttctttgtc
    15481 ttcccgaaat cgagcatact ggagtaaagt attaccatcc atcacttgct ctcctttgtt
    15541 tatatatacg ccatctaaat ctagagattt ttctgcatcg atcttgactc caccaggaaa
    15601 cagttcatta acgcaatcga taaaatcttg aaatgtgata cttgcataat agggagcttc
    15661 aaatttgaaa ttttccttta atgtttgatt taataaatca actcccccat aagagtaagc
    15721 tgcatttatc ttattcattc cgtaacctgg aatatcgaca tatgaatctc tcatgataga
    15781 gatcagtttt gcttgttgtg ttttctggtt gtattgtgca accagaagtg aatccgagcg
    15841 acctccacca atcgatcttt tttcaccgca tctcctcctc acacagcaat ccacttgtca
    15901 ggtgaggagc gagtttgtct catcaaataa gtcagtcaca aaaatataaa gaaaaggtca
    15961 gaaacctttt cgaacaagaa ttctgaccta gcatcatctc atcgtccgag ttttagcact
    16021 atacaacgta aagaaaacat tcttagctat tggaaaaagc cttaatccaa cagtttctgt
    16081 tttacccatt ggcgactttc gacgtttctg ggcaacagcc tatgtttgta taggagcctc
    16141 acctaacaag gttattacta tattctattt acgagttcat gatagacttt tcctaatgat
    16201 taggcaatgg aatttgaaat gaaatagtga aatttaacaa tctttaatat tttttagaaa
    16261 aaaataacaa ataagttgaa agaatcccgt tgcaaattct ttcagttgca ccaggattct
    16321 ttgataattt tttagtttta tgtgtttttt tatatgtttt ttcacttttc ggaataaata
    16381 tttatttgtt aaagtaatta aacaatccgc taatcgtttg atctggcatt tctatttcct
    16441 taccatctaa agtaacagta gtaacgacaa aatggtcttg caatggcgga acttctaagt
    16501 actgcccttg cagaaaatca ttcactgttt catattcttt tttcatttct tttgaatctg
    16561 tcgatggttt atagcttatt tttaacataa ctagtgctcc tttttattcg ggacgtgcaa
    16621 tcgtgaaaat ttctcctatt gctgcataat catttcctgc caaacggctt acagcattca
    16681 attttcttgg atcgatcctt cctgtcttat catcatagac tgtttcattt aaatgatatt
    16741 tctgtacttc tagcaaaaat aaatcagctg ttactttatt tttattccgt atctcgacat
    16801 gttcatataa ggatgtttca aaacgaactt ttgcttctgt caatgctggt actgaaatga
    16861 ttactgaatc agttaaagtc aagtcagtca ggtacagttc gctttcctca ttaggcagat
    16921 tggctgctgt tttatttact tcttctacgt tgtcctcatc aaggatatgg ataacagctt
    16981 ctcttgtctc aagaatattc tttgctgtgt cttttactgc atcttgtttt ctctggatcg
    17041 ccaaggataa gatgggtcga ttcgaactga cgatattgaa gtaactgaag ggtgcgatat
    17101 tcactatatc ttttgctgat ttagtcgtta ctactgctac tggtctaggg atgactgaac
    17161 caatcagcaa cttgtaattt tcacgttctg tcaattctga aggactccgt tcaaacatgg
    17221 tttcgccttc tttctataaa attcgttaaa aagcagatct tgaagacaaa atgaaaagta
    17281 atgctttttt catcttctta gaatctgctt taaactatct atcaattttt cttttttgtc
    17341 aagaatctgt gccgtgcgtg ttttttagtt atttgcttta cttgcggctt cgacatatct
    17401 tttagtgatc aattgcggac gggtgataat agatccaact acgactgaaa aagcacctaa
    17461 ttcatatgct ttctctactt gttcaggaga gtcagtatgt ccttccataa ttactgggat
    17521 atcgacttgt tctatgattt gattcaataa atcaaaatca ggtgtctgcg tctttcgtga
    17581 atattctgta tagcctgcta aagtcgtaga caaaagatca aaaccatctt cttgcgcttg
    17641 aagcgcttcc tcaaaagtcg aaatatctgc catagctaac cgaccgtgtt cgtgaatcat
    17701 ttggacaagt tcagcagttg ttttttctgt cggacgttta cgagaagttg catccagtgc
    17761 aatgatttct gcttgcgtct ccaaaagttc ttccacttct ttttctgtcg cagtaataaa
    17821 cacttctgac ccatcgtaat ctcttttgat aatccctatt accggtaaat caacgattcg
    17881 cttgatttca ttgatatctt ctgtcgtatt tgctcgaata ccaactgctc cgccttcttt
    17941 tgcagccaaa gccattctcc ccataataaa agaactgtgt agcggctcgt tttccaaagc
    18001 ttgacaagaa acgacgactc cgcctttgat ttgttccagt gtatccacaa tatctcctcc
    18061 agtaatgtta tataaaaata cagcttcata taaaaatgta acccttttct attcaggaga
    18121 caataatgag ctatttcttt cagcagacct ttcttactaa aagaaaatta cttcaaattc
    18181 ttcgtatacg accagcttct cttctgtaaa ttctatgttc aacgcttctt tataagcatg
    18241 tttaaaaaac tcagcatgga ctttccgcca ataagctaat gtccgatccc cttctccttc
    18301 tttccaagca tgctctttcg tgacttcact aaaaggcaag atggtcacat ttatattttt
    18361 gatgatacaa actggttcat tttttccatt caggaccacg tctaattgac caacttttgg
    18421 taaaggctca ttctcttgtt tatacagatc gtaaccactt gatgtaccag tctttatctt
    18481 ttttacaact agttcgctca actcgtctgc cattttttct gtatccccaa atgaaaagaa
    18541 acctaatttt tctgattgat aactaggata tttttcttgg aactttttga catattcttc
    18601 tacttgctga tacataacat ccaccccttt gctttttata atgaaaaaac catccagata
    18661 ctagtataaa caattatctg gatggtgagc ataatgaatt attgaatatt caagacacgc
    18721 agactatctt caacgatttg ttttggtgtt aaatgataac gttcataaag ctgccctaca
    18781 ggaacgctat ccgtgaattc tttctctgca ccaaaattta atacgttcat tgaagaatca
    18841 ccataataac gactgatatt ttcgccaaat cctcctgaca aactaccatc ttctaatgtg
    18901 atgactaatt cgtgtgtttc ttttaattta tctaatgttt ctacgtcatt ttctgtgatc
    18961 gttcctggat tgatcaacgt tgcttcgatt cctttttttc taaaagcttt tactgtttct
    19021 tttcctaatt caagaaaacc gcctaaagct aaaattgcta cttttcctcc attatttact
    19081 gtttgatagg ctggaatact ataatcattt gcgatagctg taccatgttc tacaccatgt
    19141 gtaggaattc ggattgctac aggctgcgct gtttgttcga acgcccaatc tagcatagag
    19201 atcatatcct cttttgttgc tggagcaaga tatttgatgt tcgggatact tgataagtaa
    19261 ggaatgtcaa atgttccttg gtgtgttcgg tcactagctg agatcgttcc gccaccgact
    19321 aaaataatca ctggattctc gttgatcgct aaatcatgtg ataattgatc atatgcccgt
    19381 tgcaagaaag tacttgattg gaagacgact ggacgtactc cctgagaagc caaagcagaa
    19441 gcgaaagtga tagagtgctg ttcagcgatc cccacgtcaa aataatgatc tggatgtttt
    19501 tcttggaatg ttttcagtcc aaaggcgcct ggtatcgctg cattgactgc ggcaatagga
    19561 gctgtacttg tttgcatttt cttatccaaa taatccatga tgatcatatt aaatgtttct
    19621 ccagaagtta cttgctttgc ctccccggtg gacagatcaa atggtacatg ccaatgatat
    19681 ttcattttat tatcgattgc cggctgataa ccgcgacctt tttccgtatg gacgtgaagt
    19741 acaatcggat gatcaatatc ttttacttct tcaaataaac ggatcaccgt ttccagatcg
    19801 tttccattat ccacgtaacg ataatcaaat cccattgctt taaataggtt attgctgctt
    19861 ttaccgttgg tttgacgaag ctcagctaag tttttatata aactgccatg attctcatca
    19921 atagacatct cattatcgtt tactaatacg attagattgg attgtaaaac accaccattg
    19981 ttcaatcctt caaaagctaa gccaccactt agggagccgt caccgataaa tgctaccaca
    20041 tttcctgatt ctttcttcag atctctcgct ttagctaaac ctgttgctaa gctgatagat
    20101 gtagatgtgt gccccactgt aaaatagtca tgtttacttt catgttggtt ggaatatccg
    20161 ctcacttcac ggtaatgtcc tttttcaaaa ccattttttc gaccagttaa aagcttatga
    20221 ccataagact gatgggaaac atcccaaacg attttatcct ttggtgaatc aaatacataa
    20281 tgaaacgcaa tcgttaattc tactacacct agattcggac caacgtgccc acctacatcg
    20341 ctgtcctttt gcaagatttt ttggcgcatc tcttctgcca actgtttcat ttcctcaaca
    20401 gataattttt tgacatctgc ggggctattg attgcatcca atacatgtaa tactgtactc
    20461 ataatacatt ctctcctccg tactatcttc ttttaatgaa aatagatttg ttacacttta
    20521 tctattctac tacttagagt tgactctaag tcaatagcat tttaaaaaaa tttcagagaa
    20581 agcttgttat ataagtagat cttcgcacga atcaggactc aaataaaaac cttctacaga
    20641 caattaaaaa gctttgtaga aggtctccta attaaggtct catcaagaaa tatgtttttt
    20701 taataggtga agttcctgag caatatgata caaatggatg tttgcacctt ttaatgagat
    20761 tggatagatc tttgtctttt cagtttctaa tccattttga tagctagcag catcgcacaa
    20821 aaccactctt tttttcgcac atagacattc atcaggcaat tcttctaatg aacgaaataa
    20881 aataggattt atttcagcga tgccttcttc cgcatacaaa tgaaattggg ttcgataaaa
    20941 aaattgtttg actgaacttt ctgaaacaac aaaaatttct atttcctgtc tccccgcttg
    21001 ttcactgttg atcaaagaaa gacttttgac gaattttcga atgaaatttt cattccatct
    21061 tagttggatt tgatttttct ttttccactc ttccaatatt tctacaattt ttccgtacag
    21121 aagttgttct ttttctgata gaagatagat cctttccggt aaaaatactt gtccatctgc
    21181 ccacaacgta cggacaaatt gtaaaaagga ttgcttgaaa ataaaatttt ctgcatcgtc
    21241 gatttcagcg atactaataa tctgtaaaat caattcattc agtgataggt cattgagaac
    21301 aaaattttta taaacaactt cgaaatcttt tcttaacagc tccatgttct cattggtata
    21361 atttctactg ttgaacaaag aaaaaatata atagacatct tcttcttgta agtctagaat
    21421 tcctttttgc tcttccaatc cttgacagac taattgaaat aacggcttcg tttctgcgct
    21481 tttcttatct tcttctttca gtccaagggg aaatgccttt cttccgattg cgatctctat
    21541 tcctcgtatg ataaaggact tttcatcttc cgaatatctt cttttaaaaa aatgagtctc
    21601 tacataatca atcaactcgt tacaagcttc ttctacatac ggatttttat tttcatagcc
    21661 ttcccaattg acataacgta ctaaagctag caagatgttc cgcgagtcaa attctgggat
    21721 aatgatttct ttatttttca aataatcatt ttctttaaaa aaatccaata cgattttttt
    21781 gattgtatat actttgctca aagaaataaa ttcaagatca gccagttctg tactcgtgaa
    21841 tataccatta aaataataac ttaaaaactt taaaaaataa gattgaccgt acagaaactg
    21901 tgtgagctca gaaagagcaa taccatgttt gaatacgagt ttatacttat gcttctctct
    21961 tacttgttct tttatacaat attctagaca ctcggctaga ctttctagat cgtgaaggat
    22021 cgttggtgta gtcaccctta gagaaatagc tgtttgttcg atgtctattt cttggaattc
    22081 aaataattgt tcacacagat acacttttct aaatatattt cgctcgatgt aattttccag
    22141 cattcctgat acacgcctcc agtttttctt atgattttat ttaatcatat ctgtaaatcg
    22201 tatttttgtt tcctttttat ttagaaaagc cctttcaaaa accaataaaa aaagaaactg
    22261 ggacaaaagt caaacaagct cacaatttca gcctcattgt aggtagcttt gagccgtttg
    22321 gacttttacc ccagcctctt tcaagaatgg ttattcaaag atgtcagcgt ctagttcttt
    22381 gactacatct ttcaacaatt ggataccagc tgcgctgtta ccaaatggat ctagtgccgg
    22441 gctgaagaca cctatgccgt aacgatttgg cacagctgcc atcaacccgc cgcctacacc
    22501 gctttttgca ggtacaccaa catggacgga aaactctcct gattcatcat acaaaccagc
    22561 agttgtcata attgatttga cgattgtagc actttcttca gtaatgattt gtttgccatt
    22621 ccaaggagca attcctttat ttgccagcac agcagctaat tttgctatgc ctgtagcggt
    22681 gacattgagg gagcattgtc tgaaataagc atcgagtatc tccggtacgt ctccttcgat
    22741 catttgatta cctttcatat agtaagcaag agagcgattg atatcacctg ttcttgattc
    22801 agaatgatag atttcttcat tcaatgtgat attaggatca tcacagatct ctttcataaa
    22861 tgacaagatt cgctcaaatt tttcatctgc atctttaccg gcaatcaacg aggttgttgc
    22921 aatcgctcct gcattaacaa aaggattcat tggatgtttg cgatgattga tttccatatt
    22981 catgatagaa ttgaaggcaa aaccggttgg ttccgtgttg attgtttgaa agactttttc
    23041 tattccgttg tctttgattg ctaataacaa tacgggaact tttgacatgc tttcgatggc
    23101 aaagcgcaca tcggcgtctc ctccctcaat cagttgtttt gtatccaaat cataaatcgc
    23161 catacctaat tgtttgggat ccacttcagc taatgctgga atgtaatccg ccacttgtcc
    23221 tgtttgataa tagtggaaat tttttccaat caattgttct aattctttta cttccatttg
    23281 aataaccagc tttcattttt tatttttctg catgctggaa tttatgacgg catgcgtaga
    23341 tcgtaaatgg aataactaag acgataagat aagaaacaat cagaatcgtt tcataaatcc
    23401 catgctgtcc agctgcgata ctagcaggtg gaacaaatga gatacaaaaa gcaaaaagtg
    23461 aagtcaaaag acctaaacaa gcaacgatta cttttacaac ttttccgcct ggaacctgat
    23521 aggctctttc aagactgtca tctttaaaaa ccagcttcaa atagcccgcg aaaaacataa
    23581 agtacaacat caggtagatt acaacagtca atgacatcgc tgcaagaaat gaaagattat
    23641 tccccccgcc gcttaatgta aagacggctg cccagattgt tgcaacgatc ccatttgcga
    23701 tcatcaaatg agcaggaaca ccgtgtgtgt tttcttttgc aaaatattca ggaagtaatc
    23761 cttcttctgc tgctacgtga agtgcttttg aaggagaggt tacccaagaa gcaatttctc
    23821 cgatgacacc taaacaaaca agaatcgcaa gaattttcgc aatccatgca agatttggat
    23881 caatgtgtct taataggaat tctaacgatt gaatcacccc tgtattaaga gacaaaccat
    23941 gttgaggtac tgtagtagcg acggtcaatc cgccaaaagt atctaaaatg attgccagaa
    24001 taaccaatac aaacattgct aatggataat cctttttagg gttttccatt tcatttgcat
    24061 gactggcaga tgtttctacg cccatatatg ctaaaataaa ggaaacaaaa acaaccagcg
    24121 taggcaattt cgaaaaatca ggaatcaatg ttttcataga cagtatcgtt tgtagtggag
    24181 cgcctgaagc gacataatgg atccctaagc caaacaagac taatgctggc aacaagatac
    24241 cagctacaaa accgatccga gcaatcaatg aagtgtattt ggttcctttt aactgtgaga
    24301 gtaaaatagc ccagaaaata atcaatagga ttgccaattt cagatattta ttgttttgta
    24361 tagcaccaat acccgttgca taggataatg caccagttaa gaaatacagc atggtcaagt
    24421 agccaactgt tatctcaaac cattggaaaa agattgcggc aaaaccgaat cgttttccca
    24481 atgtgcgact gacccaagta tagacaccgc ctttttccca tcctttcacc gttgccatct
    24541 ctgctgcgca caatgccaca gggataaacc atagcaaacc gcctaataac aagaaaaata
    24601 ctaagctgaa gcctgaggtc gcgaatgtgg gatattcata taatgaaacg accattgaga
    24661 tggtcatagc caaaaagcca aagaacgtta atttttttgc aggaattttc gttttgcttt
    24721 gttgcatgaa tcttcctctt ttctatttga atttgtttca attgagtttg ttgccaaaga
    24781 agaaaaagtc caatccttct tcttgttctt cttttgtagt agtgatcgtt gtaaagtgca
    24841 tcgccgattt taaaatcact gttgtcagca cataggcata cacggcagta atgatgacac
    24901 caatcacttg aatccctaag aagtaccagc tgcttggatt cgttagtaaa tggctgttag
    24961 atgcaaagat ccctatcaga atcgtacctg tgaatccgcc catgccatga acaccccaca
    25021 catcaagtgc atcatcccat tgtttctttt tacgaaaatc aacagcagca tgacagacga
    25081 tacccgcaat gatcccaatc agcatggcac tttttgcttc tacataaccg gcacaaggcg
    25141 taatggctgc caatccagca acggatcctg ttagtacgtc gacaaaatca aagccatttc
    25201 cttttacttt tgcaatgatc agccaagtaa tcatcgcaaa tgcaagagcg atgaatgttg
    25261 aaccaaatgc attgactgct tgttcatctg ctcgaagtgc accaccggaa ttaaaaccga
    25321 accagccaaa ccaaagcagt cctgtaccga tagcagctgc cataagactg ctatgctgac
    25381 ttctttctcc taaaggaatc tttctttgac caagtgtgag gatacatgct aaagagccga
    25441 atccagctgt cgtgtggatg actgctccac cagcgaaatc tctaaatccc atctgatcca
    25501 aaaatccgcc accccatatc cagtggcaaa cagggaaata aatcagcaga ttccaaaaaa
    25561 taacaagtat aatatagcct tttaaattca atctccctgc aaaagctcct gtcatcaaag
    25621 gaacggtaat cacgataaac atcagttggt aaagaaagaa cattaaaaat ggaatcgttg
    25681 caccatgaaa catgttgggg aagcttgtaa catgtctcat caaaaagaaa tctgccgggt
    25741 ttccaataac accgccgata tcccgtccaa aggccaatcc gaatccacca aatacccaca
    25801 taatcgttgt tatcccaacg gagagaaaag attgagacat gatcgttagt atattattct
    25861 tccgtgctaa tccgccgtaa aaaaaagcta gaccaggagt catcaggcaa accattgctg
    25921 tacataaaat catgaatgct gtatctcctg tattgatagg taatgtattc atttttttcg
    25981 cctcctttct acgattacga gtataaaaga aggtgtagtt gtttttttct tctgtttttt
    26041 tgaattaata cttgcattta taaaagacag acaattaata aaagcttgat gtgttgtgct
    26101 ctttttcgtt tttcacacaa ataaagacaa aaaataaacg gtcttctttt tatagaaaac
    26161 cgtttatttt cgtctttttt tatttttaaa gatatttttt cataaggaat aaagaatact
    26221 tcatataaaa tatataaaaa agaaccgcag cgagtgtcgc tacggttctc aaatttgttc
    26281 ttcatttcaa cataagtttt tcttcaattt gcttataatt tacgtgcaaa gaatgaaacg
    26341 actaatacta aaatgattgc accgatcaat gatggaatga tagccattcc tgcaattgtt
    26401 ggtccccaag ttcctagtaa agcttgtcca attgctgaac ctactaaacc agcaatgatg
    26461 tttgcgatga tccccattga tgatccttta ttcgtgattg ctcctgcaat tgctccaatg
    26521 ataccgccga cgattaatgc ccaaataaat cccattttaa attcctccta actgacttct
    26581 tacttcttat tgtacacgtg gttcgttatt ttctttgact ttttgtgcac ctttgcctac
    26641 agcagatttt gctttatctg tttggcgtga agcaaattgt cctgtggatt ttgctgcttc
    26701 tgttactttg tcttgtactg tttcttgatc tttttggtat tcttcttgtg ttttgatgtc
    26761 tgcaacattc acattcactt cgataacatc taaatgtgtc atattgttta cttcagtact
    26821 gatcaattct ttgatttggt tgtaaatatc ttcgatgtct ttaccgtatt ctacgatcac
    26881 atctagatcc acagctactt gtttcttacc tacttctgta ttgatacctg ctgttacgtt
    26941 atctgtgttg actaattttt cagccatatt tgagaaaaat ccgccatcta atgtcaatag
    27001 accatctaca tctttcaatg cataaccgat gattttttgg atgactttgt cttcataagt
    27061 caattcacca ttcatcatgc ggttttctcc tttttcattt gccaaaactg atccatttgt
    27121 tgtattcatg tttttgtttt ccatctttgt ttcctcctat gatttaaaaa attgatcaac
    27181 tattcctgac tgtttcaaat aaaaaccgat tcctgcgcca attgctgtca tgattatgat
    27241 caacaatgtc ttgaaaaatc caatcgttaa ccataaaaca gctagcagta gtccaagacc
    27301 cccaaagata atagggagct tgtatgctga aaatagttct ttcattattt ggccctccta
    27361 ttccactcga gagtgcttgt agtctcttgt atcttcttgt tcttcataac cgctgtatgt
    27421 gactgccact ttgaccgttt cttttgttcc gagtacttta gttacttctt cttcgatatc
    27481 ttgcatcaat acacctgttt tccctactaa tgaagaagtt cgtttcaagt ctccgttgac
    27541 atggatatgg attcgatttt tcgttgaacg tatccgtact ttaggtgaat gaatgaactc
    27601 ttcttcgtgt aaatgggaac gtaccaaccc ttcgatcgct tttttgtcga ttgttagttt
    27661 gccatcttcc cgtttcataa cgaaagttcc tcttgacttt ggatagaaaa gaacgactag
    27721 caagatgata atagcaagaa cggcaaatac tacagctgcc cagaaaatat attgttgcat
    27781 gtagtaattc gttaaagtaa agaagcgaaa tcgttccaat tgttcaggca taatatacgg
    27841 cgcattgatc aacgcaatcg ctagaaatac tgaaagtagc agtaaactca tgataacacc
    27901 gattattttt aaccccttat tcattttcca cctcctataa acttattttt accctgtaaa
    27961 taactctacc gacaatcaca gtatagatag cgaacagtta gcatagcatc agtaaataaa
    28021 gcgctaccaa acattgctgg atcataacgg cgttttattg ccagtctgat actgaaataa
    28081 caattgctta cttattctct atttactttt gattgctggc tatacttaaa ggatattatt
    28141 caagattaaa aattgcaaag attatgctca gttattatta caagattcta tttatt
//
LOCUS       DAXLPY010000030        27597 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.030, whole genome shotgun sequence.
ACCESSION   DAXLPY010000030 DAXLPY010000000
VERSION     DAXLPY010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.030"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            38..126
                     /locus_tag="ACF3UF_001433"
     tRNA            38..126
                     /locus_tag="ACF3UF_001433"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:72..74,aa:Ser,seq:gga)
     gene            141..212
                     /locus_tag="ACF3UF_001434"
     tRNA            141..212
                     /locus_tag="ACF3UF_001434"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:174..176,aa:Glu,seq:ttc)
     gene            228..300
                     /locus_tag="ACF3UF_001435"
     tRNA            228..300
                     /locus_tag="ACF3UF_001435"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:261..263,aa:Val,seq:tac)
     gene            310..382
                     /locus_tag="ACF3UF_001436"
     tRNA            310..382
                     /locus_tag="ACF3UF_001436"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:343..345,aa:Asp,seq:gtc)
     gene            418..493
                     /locus_tag="ACF3UF_001437"
     tRNA            418..493
                     /locus_tag="ACF3UF_001437"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:451..453,aa:Phe,seq:gaa)
     gene            495..575
                     /locus_tag="ACF3UF_001438"
     tRNA            495..575
                     /locus_tag="ACF3UF_001438"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:529..531,aa:Tyr,seq:gta)
     gene            582..655
                     /locus_tag="ACF3UF_001439"
     tRNA            582..655
                     /locus_tag="ACF3UF_001439"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:614..616,aa:Trp,seq:cca)
     gene            658..730
                     /locus_tag="ACF3UF_001440"
     tRNA            658..730
                     /locus_tag="ACF3UF_001440"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:691..693,aa:His,seq:gtg)
     gene            742..813
                     /locus_tag="ACF3UF_001441"
     tRNA            742..813
                     /locus_tag="ACF3UF_001441"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Gln,seq:ttg)
     gene            859..929
                     /locus_tag="ACF3UF_001442"
     tRNA            859..929
                     /locus_tag="ACF3UF_001442"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:891..893,aa:Cys,seq:gca)
     gene            950..1034
                     /locus_tag="ACF3UF_001443"
     tRNA            950..1034
                     /locus_tag="ACF3UF_001443"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:984..986,aa:Leu,seq:caa)
     gene            1096..1168
                     /locus_tag="ACF3UF_001444"
     tRNA            1096..1168
                     /locus_tag="ACF3UF_001444"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1129..1131,aa:His,seq:gtg)
     gene            1178..1249
                     /locus_tag="ACF3UF_001445"
     tRNA            1178..1249
                     /locus_tag="ACF3UF_001445"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1210..1212,aa:Gln,seq:ttg)
     gene            1267..1351
                     /locus_tag="ACF3UF_001446"
     tRNA            1267..1351
                     /locus_tag="ACF3UF_001446"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1301..1303,aa:Leu,seq:caa)
     gene            1606..2481
                     /locus_tag="ACF3UF_001447"
     CDS             1606..2481
                     /locus_tag="ACF3UF_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFD3671573.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            2585..3349
                     /locus_tag="ACF3UF_001448"
     CDS             2585..3349
                     /locus_tag="ACF3UF_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFD3671574.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            3336..4778
                     /locus_tag="ACF3UF_001449"
     CDS             3336..4778
                     /locus_tag="ACF3UF_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3671575.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            4789..6119
                     /locus_tag="ACF3UF_001450"
                     /pseudo
     CDS             4789..6119
                     /locus_tag="ACF3UF_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            6132..6590
                     /locus_tag="ACF3UF_001451"
     CDS             6132..6590
                     /locus_tag="ACF3UF_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFD3671576.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            6882..8183
                     /locus_tag="ACF3UF_001452"
     CDS             6882..8183
                     /locus_tag="ACF3UF_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3671577.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            8210..8470
                     /locus_tag="ACF3UF_001453"
     CDS             8210..8470
                     /locus_tag="ACF3UF_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFD3671578.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(9469..10704)
                     /locus_tag="ACF3UF_001454"
     CDS             complement(9469..10704)
                     /locus_tag="ACF3UF_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3671579.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            11271..12098
                     /locus_tag="ACF3UF_001455"
     CDS             11271..12098
                     /locus_tag="ACF3UF_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3671580.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            complement(12371..13141)
                     /locus_tag="ACF3UF_001456"
     CDS             complement(12371..13141)
                     /locus_tag="ACF3UF_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3671581.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            13359..14426
                     /gene="ulaG"
                     /locus_tag="ACF3UF_001457"
     CDS             13359..14426
                     /gene="ulaG"
                     /locus_tag="ACF3UF_001457"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFD3671582.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            14444..14905
                     /locus_tag="ACF3UF_001458"
     CDS             14444..14905
                     /locus_tag="ACF3UF_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3671583.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            14925..16409
                     /locus_tag="ACF3UF_001459"
     CDS             14925..16409
                     /locus_tag="ACF3UF_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFD3671584.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            16452..16751
                     /locus_tag="ACF3UF_001460"
     CDS             16452..16751
                     /locus_tag="ACF3UF_001460"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3671585.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            16766..17404
                     /locus_tag="ACF3UF_001461"
     CDS             16766..17404
                     /locus_tag="ACF3UF_001461"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFD3671586.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            17409..18269
                     /locus_tag="ACF3UF_001462"
     CDS             17409..18269
                     /locus_tag="ACF3UF_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFD3671587.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            18259..18969
                     /locus_tag="ACF3UF_001463"
     CDS             18259..18969
                     /locus_tag="ACF3UF_001463"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFD3671588.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            19201..19635
                     /locus_tag="ACF3UF_001464"
     CDS             19201..19635
                     /locus_tag="ACF3UF_001464"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3671589.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(19732..20031)
                     /locus_tag="ACF3UF_001465"
     CDS             complement(19732..20031)
                     /locus_tag="ACF3UF_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671590.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(20300..20494)
                     /locus_tag="ACF3UF_001466"
     CDS             complement(20300..20494)
                     /locus_tag="ACF3UF_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671591.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            complement(20722..21483)
                     /locus_tag="ACF3UF_001467"
     CDS             complement(20722..21483)
                     /locus_tag="ACF3UF_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFD3671592.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            21803..22048
                     /locus_tag="ACF3UF_001468"
     CDS             21803..22048
                     /locus_tag="ACF3UF_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671593.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            complement(22232..22981)
                     /locus_tag="ACF3UF_001469"
     CDS             complement(22232..22981)
                     /locus_tag="ACF3UF_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3671594.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            23167..23871
                     /locus_tag="ACF3UF_001470"
     CDS             23167..23871
                     /locus_tag="ACF3UF_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFD3671595.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            23911..24468
                     /gene="hxlB"
                     /locus_tag="ACF3UF_001471"
     CDS             23911..24468
                     /gene="hxlB"
                     /locus_tag="ACF3UF_001471"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HFD3671596.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            24476..25615
                     /locus_tag="ACF3UF_001472"
     CDS             24476..25615
                     /locus_tag="ACF3UF_001472"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008926 - mannitol-1-phosphate
                     5-dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0019594 - mannitol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFD3671597.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEIYSLLSEKEQENFDEYAYFVNTAIDRQ
                     SLGKVLGGKMISVVEPYYEWIMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAA
                     HAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKT
                     LNRHGNQKLSDEITRVGSSPIRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYR
                     NLADPEAEQLRRMIVNDGLKATIKKISRLEGKLLNEVVAAYESQI"
     gene            25627..26058
                     /locus_tag="ACF3UF_001473"
     CDS             25627..26058
                     /locus_tag="ACF3UF_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3671598.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            26072..27517
                     /locus_tag="ACF3UF_001474"
     CDS             26072..27517
                     /locus_tag="ACF3UF_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HFD3671599.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
BASE COUNT         8912 a         4341 c         5696 g         8648 t
ORIGIN      
        1 ctcattttga gaaagagtat tgagcttctt tcactctgga gagttgtccg agaggccgaa
       61 ggagcatgat tggaaatcat gtagatggtg caaactgtct caagggttcg aatcccttac
      121 tctccgtagc aaatttacct ggcccgttgg tcaagcggtt aagacaccgc cctttcacgg
      181 cggtaacacg ggttcgaatc ccgtacgggt cattttaatt gaatgttgga ggtttagctc
      241 agctgggaga gcatctgcct tacaagcaga gggtcagcgg ttcgatcccg ttaacctcca
      301 taatgaactg gttccgtggt gtaggggtta acatgcctgc ctgtcacgca ggagatcgcg
      361 ggttcgattc ccgtcggaac cgtcgttctt gttattcaat taataatttt aaaatatggc
      421 gcggtagctc agttggtaga gcaacggatt gaagctccgt gtgtcggcag ttcgattctg
      481 tcccgcgcca ccatggagga gtagcgaagt ggctaaacgc gacggactgt aaatccgttc
      541 cttagggttc agtggttcga atccactctc ctccatttta taggggcata gtttaaaggt
      601 agaacagcgg tctccaaaac cgttagtgtg ggttcaattc ctgctgcccc tgccatggcg
      661 aatgtggcga agtggttaac gcaccggatt gtggctccgg cattcgtggg ttcgattccc
      721 atcattcgcc ctttttattc ttggggtata gccaagcggt aaggcaaggg actttgactc
      781 cctcatgcgt tggttcgaat ccagctaccc cagtttctat aatttattct ttattttgta
      841 gattgataat agtataatgg cggtatagcc aagtggtaag gcagaggtct gcaaaacctt
      901 catcaccggt tcaaatccgg ttaccgcctt agtactaata aatcaacttg ccggcgtggc
      961 ggaattggca gacgcgctgg actcaaaatc cagtgcccgt tgagggcgtg ccggttcgac
     1021 cccggccgcc ggtattgact aagatgtctt catcttagtt ttttattgag aaattaaata
     1081 acatctttta tgatggcgaa tgtggcgaag tggttaacgc accggattgt ggctccggca
     1141 ttcgtgggtt cgattcccat cattcgccct ttattcttgg ggtatagcca agcggtaagg
     1201 caagggactt tgactccctc atgcgttggt tcgaatccag ctaccccagt tattattttt
     1261 aaatttgccg gcgtggcgga attggcagac gcgctggact caaaatccag tgtccgttga
     1321 ggacgtgccg gttcgacccc ggccgccggt ataattatca atatagcaac tttcttatag
     1381 agagttgcta tatttttttt gtttttatgt aattacctcc aaatcaattc gatacaagta
     1441 ttatcataaa acgagtaaaa aagatattga taacgctttt attatgtgtt aaactatttt
     1501 tgtaaattat gtagggtgct actattcaat taggcacgac ctaagaaagg gttctttctt
     1561 aggtcgtttt ttgtctttaa aaattgtttg gagacaaaaa tatgtatgaa ggagtctgca
     1621 agttgttttg ttttatcata tagtggaggt gaattaacgg tgtatgtgat gaaaaagctg
     1681 aatcataatg ctgtattgat cgatgacgat ggaatagaaa aaattgcgat ggggaaaggg
     1741 attggctttt ctgctaaagt gagtaagcca tttgatgttg aggatgctga caaattattt
     1801 gtattagatt ctaaagaaaa gatcaaacga ttcagtgaga tagtctcgca gattccaatc
     1861 gaatttatgg attttgcgga agaagtgatt gaactgataa cagctaggat ctcctctcca
     1921 ttagattcaa atatctatat tacattgaca gatcatattt attttgctat tcaacgaaaa
     1981 agagaagata gagatgtcac agcaattatg ttgccagaaa tgagattcct ttatccaaat
     2041 gaatatgata tagcaataga agtggtcgag cgaatcaatc atcgatatca aaccgagtta
     2101 gggtcaaatg aagtaggatt catcactatg catatcatta atgctgagct aggagagcct
     2161 aatagtttaa agagcttaaa aatagtagaa atgacgacca cgattttgtc ccatctagaa
     2221 aaatcctatt caaacgttta tgataaagaa tcactgactt atcatcgctt aatggttcat
     2281 atcaaattcc tggttaaacg cttgatttat caggaagaaa cgccagtaga aaatattggt
     2341 ttttttactg aaacatttaa acatagcaaa gcgtattgta cagcactaaa gattaaagat
     2401 atcatcgaac agcaatttca acttgccatt caagaaaatg aaatcatcta tttggcaatt
     2461 catctagcac gaatctatta aaataagggc gtaactatct ataggcgcaa ccaaatgaca
     2521 catagtaaat ggactatgat tatttggttg cgcctatttt agtagaaaaa agaaggagaa
     2581 tgaaatggga aaagtgattt ttaattcgga tgattttggc tatagccatg gtgtgaatta
     2641 tgggattatg gatgcttatc agcgaggaat tttgacatca actacattga tggcaaatat
     2701 gccgggtttc gagcacgctg tgaaactaag aaaggaaatg cctaggctag gtgtaggagt
     2761 ccatttaaca ttgacgtgtg gcaaaccact tctcaaaact gtcgatactc ttatcgaaag
     2821 cggagagttc agatccttat cttattatca gcatccattt aacattgaca aagatcaact
     2881 gtatcaggaa tggaatgctc agattcaaaa aatttatcat gcggggatca taccaactca
     2941 tttagacagt catcatcata ctcatacttt ggatgaaaac caggaggtag ttgttacatt
     3001 agcaaaaaaa tatgatttgc cggttcggag caactttgaa cgaaaagatg aagttcgtca
     3061 tgtcgattat tttgagcctt gtttcgatgt cgtaggagaa actgatgaaa aaaaacgaca
     3121 aatcaatacg agtgtggaag aatatttggc aagtttactc atgatattga gagaagataa
     3181 aacgatcgaa gtcatgtgtc acgcagcgta tttggatcag gaattgttaa atggttcaag
     3241 ttttgtgtat cctcgtactc accaagtcga atttttaatt cattcagcat ttgctcaaaa
     3301 agtgaaaaat gatcctttga ttgagttagt aacatatgag gatatttaat agaggaggaa
     3361 taaaaatgaa tgttaaatca aatgtgcaga agcttggaag agcgatgcta cttccagttg
     3421 cagcgatgcc attagcggga ttgatcatgc gtttatcagc tgatgatatg ctgaacatcc
     3481 cagtaattgg tgcagctgga aatgccgttt ttggaaactt ggatatctta tttgctatag
     3541 gagttgcaat cggttttgtc aaaaataagg acaaaggaat acctgcactt actggttttt
     3601 tagcgattgc taccttgaaa aaaggcttag aaatcatgga cccagaagtg aatatgggga
     3661 tttttggtgg aattatttcc ggtttagtag cggcatggac gtataatcgc tttaaagaac
     3721 aaaaattacc agtagttttt tcttattttg cgggcgaaaa attcccattg actatggtga
     3781 tgattctaca aacaatcgca gctatttttt tgggctttat ctggccgctc atccaaattg
     3841 ggattgataa ttttgcaaaa ctgctcgttg atatgggggc attaggtgtg gggatattta
     3901 tgtttttgaa tcgtttgctg atcccctttg gactgcacca tgtgttgaat acgtatattt
     3961 attacgattt aggaagctat acatctccta gcaaggaagt tttcagagga gagatgacac
     4021 gctttatcaa cggagatcct caggctggac tgtttttatc aggttttttt gtagtaatga
     4081 tgtttggtat accagctata tgtctagcta tctataaagc agcttataaa gaaaataaag
     4141 agatggtcaa aggaatcatg ggaagcggtg caggaacttc atttattgca aatatcactg
     4201 agcctgttga atttagtttc atgtttcttt ctcctatgtt gtacgtgatc catgcacttt
     4261 ttgccggttt agcagggatt gtctgttact tattcaatat acgaattggt tttacattcg
     4321 gagcatgtat tgttgattat ctcatcaatt ttcgaatcgc taccaatgct attttgattc
     4381 ttccaatcgg aattttcttt tttgccttgt attacgttac tttttattat ttgatcaata
     4441 agagaaacat tcagacatta ggacgtgaag ctaaggcaga gtttggcaat gaagtaacct
     4501 tagaagaaac agagttaggg ttagcaagta aaaattatga atatatggca acaaaaatgc
     4561 tacaagcgtt tggaggaaaa gccaatatcc tggatgtcta tagttgtaat acacgcctac
     4621 gggtagaggt agtggatccc accatggtcg aggaacagcg aatcaagcaa ttagggataa
     4681 gcgggatcat taaaccaact gaaaaaaatt atcaaattat catcggctta gaagtgactt
     4741 atgttatggc agaattcaat aaattattag aagaatagaa aggaaaagat gatgatgaaa
     4801 aaacagatta tcactatagc tggaggcggg agtacgtata caccaggaat cgttcaagcc
     4861 attttgaaca atgaaaaacg gttgccatta tctgaaatac gtttatatga tattgatgaa
     4921 gaaagaaata tggatatgta cttgattgtt aaatttatgc tgaaaaaaaa ggtttttcaa
     4981 atattcgcat tcgtgcaacg gatgatccaa agcttgcttt tacaggatgc gattttgttt
     5041 tctcacaaat tcgtgttgga ggattggaga tgcgagaaaa ggacgaaaag attccactta
     5101 aacatggatt agtaggacag gaaacgtgtg gactcggagg atttgcttat gggatgcgct
     5161 caatcaaagg tttattggaa attgtcgatc atatacaaga ctatgccccc aaagcatgga
     5221 ttttgaatta tacaaatcca gagtcgatcg tttctgaagc tgttcgtcgt aaatatccga
     5281 atgtaaaaat gattaatgcc tgtgatatga ctatttcaat tgaagaaacg attgcagtga
     5341 attacggtta tgatcgtaag aattggatcg ttacgtatta tggtttaaac cactttggct
     5401 ggtatacatc gatttatgat aaagaattgc aacgagaaat tatgccagag attattgaaa
     5461 aactaataac aaaagaaatg caagtcgccg attttaatat aggagacaaa acttggcaaa
     5521 aaacctttca aatgatgtca gtcatcacga aaaattttcc aagtaatatc ccgaataatt
     5581 acttagagta ttacttatat cctgatatgg tcgttgagca tactgacaaa gagtatacac
     5641 gtgctaatat ggtcatggat ggacgagaga aaaataccaa agaaatggct gataaaatac
     5701 gccgcggtat tgtggaagaa gtattgaact ttaattttgg ggagcatgga caatatatcg
     5761 tcgatatagc tatttccttg ttgaatgatg atcgtcgtcg ctttatgcta atcgttccta
     5821 atcaaggggc gattccgaat ctacggtcag atgcagttgt tgaaataccg gcatatgttg
     5881 gtgcaactgg tgtggagaca attacactaa gaaaaccaat cagtgatttt cataaaggat
     5941 tgatggaggc acaagttgca gcagagaagt tactagtaga tgcttacttt gaaggttctt
     6001 atcaaaaagc tttacaagca tttacattga atcaaaccgt accaaatgcc agagtcgcaa
     6061 aaaaaatact agatgaaatg atcaaagtaa acaaaaaata ttggccagca ttaaagtaga
     6121 ggtgataaaa agtgcatttc tttaaaacaa gaaacattct aaaagctgta gctagtggtc
     6181 aaattattcc attaacagca gtaaaagacg aggtcttttc ttcaaaaatg ataggagttg
     6241 gatacgctat aacgaatcat gatggatata tccatgcgcc agttaaagga ataatcgata
     6301 atatatttcc tacccgacat gccataacga tcgaaagtga atctggcaga aaaatactga
     6361 tccatatggg tttagataca gttgaactcg aaggaagtcc gtttcagata cgggttgaaa
     6421 gtaaccagga ggtaaaagaa gggacactgt tagctattat agatttgaag aagttggagc
     6481 aagcacaaaa agatacggtg atcattgtag tttctccagg catttttgaa ggaaatttat
     6541 taaaacaaaa ccaagaagta aagattaaag atagttgttt tgaattttag tgtacgatga
     6601 aaaaagttaa atagggtgat atttatgggt gaatttacaa aatttttttg aaatgataag
     6661 tttcaatcac tagatttaat cattttgatt tttgttaatt atcgaatttt tttgttgctc
     6721 ctatgattta gaaaacttat tttcaggatt cttaaaaata aatttgatta tttaagagaa
     6781 tatattgaaa taaaatttct taattatata attagttatg aacattcttt gcgttgtcat
     6841 gcaatgaatg gttcatattt tattgaaaag gagtggtttt agtggaaaag ctgatgaaat
     6901 gggtcgaaga gaaacttgtc ccaccaatgg caaaaattgg tacacagcgt catttattag
     6961 caattcgtaa tggggttgtt tcaacattgt cattgatttt gattgggaca ttttttatgg
     7021 tctttatcaa tttaccgttt cctggatgga atgaatttat tgccccttat tcggcaacga
     7081 ttgttttacc ttttaggatg acgatgggat tgatggctat ttatgcaact tttgttatgg
     7141 gttcggatct agctaaatca tatggattag atagtgtgac aggtggtata ttatctttag
     7201 gaacgttctt tatgttacaa gttcctgtaa acgttttaac tcctgaaaag gcacctcttg
     7261 gctgggtctt acctatgagt tctttgggag catctgggat gtttgcgggg atcttatcta
     7321 tgatttttgc agtggaagta tatcgtttct ttaaaaatcg aaatattact atcaaaatgc
     7381 cagaacaagt gccacctgct gttgcccgta gttttgaggc attgattcca ggtgcagtca
     7441 ttttaacaat tacttggctg attcgaagcg tcgcgggctt tgatgtaaac gctaccttat
     7501 tatcgttatt cgagccttta accaatattt tagggaataa tttgcttggt gttttactac
     7561 caatgttttt gatccatttg ttgtggtcat ttggtatcca tggcatgagt attgtagggg
     7621 ctgttgttcg tccaatgtgg ctgatcatgt tggatgagaa tgcaaaggca ttggcagatg
     7681 gtacagctgc cacccaatta ccctatatcg ctcctgaaca gttttatcaa tggacggtaa
     7741 caattggtgg tgcaggagca acgatcgtgg tatctgtttt gtttatattc ttctgtaaat
     7801 caaaattctt gaaagaggtt ggtcgttttt ctattattcc tggtatcttc aatatcaatg
     7861 agcccatgat ttttggagct cctatgatgt tgaatcctta catgttcatc ccgttcaact
     7921 tagttccttt agttttgact attatcagtt attttgcagt caaattagaa atggtcaata
     7981 gatttactgt tttgccaact tggacattac cagctccaat cggcggttat ctttcagcag
     8041 gaaatgactg gcgtgttgtt atcttgatca tgatcaacac attgatagca tttattatct
     8101 attatccatt tgtaaaagct tatgataaaa agatgctgtc agatgaacaa agtcgtggag
     8161 aaaacgaagt ccaaactgtc taagtttggt ttttagaagg tgggaaacaa tgtattggct
     8221 gattttattt tttgttttta tctttttatt aacggctagt caccttatat tgaatatgct
     8281 agctacatat catattcaaa tcaatcgatg gatttgggca ctggcatcat ttttgatcgt
     8341 gattcttcca aagatcattg taccgcatat gaatgttttg ttttcatggg ggacatatgt
     8401 actttgtgga atttttgcta tcaattttat gatcgagcag catagatggt ttgtcacatc
     8461 gaagctttaa atgttctaaa agtggttgtg acagaagtgg ttagcttcaa gaaataagaa
     8521 gaaatttacg aaaattgctt cttaaatttt tgtgaaatgt tggcttattt ttcgtttggt
     8581 tgaacttatt accgcagatg caagcttttg accaccgttt attcggaata tgggactgtg
     8641 acaaggcttt tgtcacagcc cttttttaca taaagattat tattgtttta actgttttgg
     8701 cagaaagaag gaggcaaaaa tgaaaatttt atcagcaatg gattaagaat tagtcgatct
     8761 actaccaaag tgatcaaggc aaatatagat ttgggagctt acaaccatat agtaggggct
     8821 gcagtatggt gtatgaatgg taatatgtat gatgagagtg tttattcaaa tcatgaaacg
     8881 tgtatagaaa taattgcgct gggaatagca atcagtcatg gtgaacgtga cttttagttt
     8941 atcgttgctg acgacataga acattctgac atgatctact cagcatgtgg ggattgctgg
     9001 cagtttatat aggagtatgc atcggattgc gagatcattg tctcaacaga agagggaggt
     9061 tgattatcaa agataaagtg gtaaatccta catttgattt agtaattgtt gaagggacta
     9121 gcagcacaaa tctctacaaa gcgatgcttc tagatctata tgacacattt taagaaaatg
     9181 tatttgccta attattatgg tctttctttt gaagaaacgt tgagatgatc caaccagaga
     9241 aaggtgtcaa agaatttgac taagaataaa tggcagacgc tacctatgct catttggatt
     9301 gcgtcagatc ttttatttta aggatgattt tgtgtttttt agacaccgta atttaagtaa
     9361 ctctaacttt tcaatccact atttactttt tttgtatttt cactgtctgg gtctcgaata
     9421 gcgaaattac tgatgagtct ctattaaaaa agctttttct acttgaaact atattgggtg
     9481 gttgctcagg aaggtttcga tttcttgaat tgcttgttgt ggaccattta ttggaaaaac
     9541 ggcttgcagc gtgcgtgcct gctgacgaat cttgggtgaa gaaacttcgc gcagagcaat
     9601 ctgcagtttt ctttcagtca ctggttttgt gagggcgatt gcgtttccgt attttacaca
     9661 atagtcaata ttacagcttt gctcaaattg catccccaca ccgataaacg gtttgccgga
     9721 ttcacaggca gtttggacgg tcccttcccc gccgtggata aaagaaaaat caatgaattc
     9781 atgcaaaaga tgactagaca gatattctgt tattaaaaga tcttctgagt cagattgaat
     9841 gtcatcaagc agatagtcaa taggtgcaat aaccgctaga tccggttgtt tttgtaagaa
     9901 gaacaaaatt ttgcgtaaca tacgcggatt gcctgaacta cccattgcga aatagataat
     9961 acgttttctt tcttgttgct ttcgctgtat aaaagttagc acttcttcag gcaaggaagt
    10021 actgagctta gcaaaaattg gaccaacgat tcgataattt tccggcagct gttcttcttc
    10081 caaaaatagt ttaggcgttg tgatgagatt tagatcagca tccatcattt gtaaacttgt
    10141 ttttggtaaa ggaagcattt ctttttgtgc agcgtgtttg aaggcattgg ggatccatcg
    10201 ggtatttact atacgctttt ttgtccagtg ccaaagggga ttgcttaaag ggccgaagaa
    10261 acgtaactcg tggggcatca gcgcatgctc tgattgaaaa aaaggttcac tcaaagcata
    10321 gggtttaaca tatactaaag gaatcttttt attgcgggcc gataaaaaaa ttgtcacatt
    10381 cgaacctgtc acaatcagtc gaggctcaaa cttagcaatc agactctgtt cactagtgat
    10441 acgagaggca accatttctt tggtaaaagg gtttttaagt gtacgcaact ggtcaaattt
    10501 tatgatttgt tcttcttgtt ttttcgtaag gatcggcgct agtaaatgat actcaaagcc
    10561 actttctgtg atcaaaggag caaaagtttt agaaaagcca aagaatacac agtaataacg
    10621 gtctttcata gctttggcaa cctcaatcat tcgtgttgtc tcagctaaat tgaatactgc
    10681 aggagcaaaa agaattgtct tcatgaaatc ctccttattg gaatgagtct atcccttcgt
    10741 ttcttactag tatactaaaa aacacagcgt tcgagtagcc tatgtatatt ttgaatatta
    10801 aactgtctct cgctgttttc acaacttcta aatttaaatt ttgtaatcaa gttgaaactc
    10861 caattttcaa aaaaacacgc aacaattttt tgatcgattt atatgttgtg ccagataaat
    10921 acgagaagtt gtgtcattaa aaataaacat gagaacataa aaaataaaat aattatatta
    10981 attgataggt gtgctgtcgt cattatacac acgtaagaaa gaaatagtta tgtttaaaaa
    11041 tattcttaga ctttctcgcc atgacaattt tcactatgtg ttataactgt aaacgataat
    11101 tattcagata acacaaaaag aaatcaagga gcagatacgc cagttgttta atttgaatat
    11161 tattttaaaa ttaaaatttt tattctgttc taaacatttt tggttgttta gaactttttt
    11221 ttgtgtatga tataaaggag aaataatttt ttaaagggaa ggaaattgtt ttgattaaag
    11281 tagatggagc attactaaaa gaataccgaa agaaaaaggg gttaacacaa gtacaattag
    11341 cagaaggcat ttgtgaacaa gcaactgtca gcaatatcga aaacaagaat atgtcgccag
    11401 gcatcaatat cttaagtgcg ctttgcaaaa agctgaatgt cgagatctcc gatatattag
    11461 tagaaacaga agaagacaaa atcaggaaaa aaataaatga gattcaatca ttgaattctg
    11521 tatcaaaata ccaagaatct tataaaattt tacaaacgat cgatcaggaa aaagtaagta
    11581 attctgatct tttaaatcaa attttatttt atcaaggact gcttgatcat ctttatgcga
    11641 aaaaaccaga tgcagcatta ttttatttta atcaagtgtt ggaacaaacg accgaaacag
    11701 atatccatca cttacaagca gctgcaaacg tggcaatgat ctacttgtca aaaggagaat
    11761 tagattttgc gaaagtttat gtggagcgta cacttaaaat attgagtgag actgattttg
    11821 ataatctgat ggtctgcatt gtatattatg atatcgccac ctattaccgt aaaatcgagg
    11881 attatgataa agcaatccaa ttatgtgaga agggtattga gtataataag aaacataaat
    11941 cgacttatgc attggaatac ttgctttatg aaattgcttc ttgccataag caattaggag
    12001 aagatgatta tttagaaaga tatatggacg caaaaaaaat agcgcgtttc aacggaaatg
    12061 attacgcggt aaaggtgatt gaaaacgacc tgaaataaag tggttgtgaa atcagtgttc
    12121 tgatttgaat accgtttatt cgaaaaaagg aggtgtgact tttgtcatac ctcctttttt
    12181 cgatattgtt tgattcctat ttaggcaaca tataacggtt ataaaagaag caatagatta
    12241 tgatggtatc gattggatgg acacatcttg ggattccttt atcaatttga gcgtagcgtg
    12301 tttttcattt atcgataaat ttgttattca tttttttgat aatcctattt acatatttac
    12361 gtcctggttc ttaaaatgaa tctacttgaa tggtttttat ccccgtattt ctgatctcct
    12421 ctaatacttt ttcagaacaa aatttatcag tgatcaaata atcaaagact gaaatatcag
    12481 caatcttgaa ctttgatgtc agtccgattt ttcgatgatc agcgactaaa atcttacatt
    12541 tgattgtctt gttgaccatc atttcgttga tcgttgattc atttaatatc tttgttgtga
    12601 ccccatgtac tacatcgact ccgctacagc caatgataca aatgtctgca ttgactgaag
    12661 aaatcgtatt taatgcgatg tcgcccacta gtgcttcttt tggaaagcgc atctctccac
    12721 cagttaaaat ataactacaa ttatctttgt gcggagagta attgattttc acgttgtttg
    12781 taatgactgt caaatggtta gattgaagaa aatccagtgt tttcaacgca gtcgagctag
    12841 aattgataaa cagcgtatca taatcgttaa tgtatttact agcttctctg gcaatcgctt
    12901 gtttaatcct ttcaggacca gattgatcaa aatcagtctg gtttttgtaa ttataagaac
    12961 aataaccgta attgcgtatg atctcgtttt tttcttctaa taaatttaaa tctcttcgta
    13021 tcgtactaat agatacatca agggattcag ctaattcgaa agttgatagt tgttcagtct
    13081 gctgaagcag ttccaaaatt tctttttgac gtttttcaat attgacaagt gagtttttca
    13141 tgacttttgc ctcctgaggg acatcttgat ccatggattt atttgactag ttgttcattt
    13201 aaacattcat atctgtcttt attatactga aacaatcatt gattactgaa agaaaatcat
    13261 ataaaaaaca aacggtcata taaaagggtt tccatggatg ctgatacaca ttaatattta
    13321 cttgtaagtt ggaacaacga tatgggggga gcaagcaaat gagtaaaact gtcaatgaag
    13381 taacaaaaga aaagtggtta gtagaaacat ttcctgagtg gggcacatac ttgaatgaag
    13441 aaatcgaaac agaagtagtg gatcctggaa cttttgctat gtggtggctg ggctgtacgg
    13501 gaatttggct gaaaagtcat gaaggaacga atattttatg tgatctatgg tgtgggacgg
    13561 gaaaacgtag tcatgggaat ggcatgatga aaaaaggcca tcagatgatg cgtatgagtg
    13621 gcgttcaaaa tatgcagcct aatttacgta ctcagccttt cgtaatcgat ccttttgcga
    13681 taaaaaatgt agacgcttta atcgttacac atatccattc cgatcatcta gatatccata
    13741 cagccgcagc agttcatcaa aattgtcctg aagcaacatt cattgggcca aaagaagtgg
    13801 ttcgcacgtg gcaaaaatgg ggaattcctg aagaaaaaac gattacagta aagccaggtg
    13861 atgcagtcaa aatcaaagac atcaatgtag tagctttaga agcgtttgat cggacagcgt
    13921 tggtcacttg tgaagatcca gaagaggtat taaaaggaaa aatgcctcag gagatggatc
    13981 aaattgcagt aaactattta ttcgaaacat caggagggaa tctttatcat gcaggagatt
    14041 cacattactc caatttattt gccaaacatg gtaatgaaca caaaatcgat gtctgtttag
    14101 gggcctatgg tgaaaaccca cgagggataa cagacaaagt tacttctgtt gatatgctgc
    14161 gcatggcgga gtcattgaat gcaaaagtag tgattcctgt ccactacgat atttggtcta
    14221 attttatggc tgattcaaaa gagatcactg aaatttggaa attcaaaaag gatcgcctga
    14281 agtatggatt taaaccttat atctggcaag taggcgggaa attcatctat ccgacaaaca
    14341 aagatgatct tgagtttaat ttttatcgag gatttgaaga tgtcttctcg attgaaaatg
    14401 atacaccgtt tccgtcgttt ttataagaaa gaaggggagt ttcttgctga aatacttttt
    14461 tgaccatcaa ttgattcatt acccagataa agaaatcacg gattggcgtg aagctatcgc
    14521 cgaaagctgt cttgtattga tcgataagga aattattgat gaaacgtatg tggaggagat
    14581 catccattgt gtagaaaaat acggtcctta tattgtgatc gcacctcaag tagcaatgcc
    14641 gcattcttca gaaaaaagtg atggtgtttt tggaacagct atttcattta ccaagttgaa
    14701 acagccaatc cgttttgaaa gtgaagggga ggatgaggag aaaacggcta gtttgttttt
    14761 tacacttgca gcaaaagatc cagaagaaca tctagaaaat atccaaaaat tatccgaatt
    14821 attaatgaca gatggattgg ttgagcgtct catctctacg aactccatcg atgattacca
    14881 agttgtgatg gcagaatata attaattgat agaggagaaa aaagatgggg gaatttttgt
    14941 taagcatttg gacgtatttt gcaacaaata tcttgacgca gccagcatac ctgattggtt
    15001 ttatcgtgtt attaggctat attttgctga aacgcccgct tcatgaatgc atcgctggat
    15061 tcttaaaggc aacggtcggt tactttattt tgactgttgg ctctggtggt ttggtcaata
    15121 attttcggcc gattttggtt ggactaaagg aacggttcaa tttggatgcc atggttacag
    15181 atccttattt tggacaaaat gctgtggatg ctggattaat ggagacattt ggccgtacct
    15241 ttggagatgt gatgatttta ttactgattg catttgtttt aaatatctta ttagtccgtt
    15301 ttcagaaata tacgaaactg cgttccgttt tcactaccgg aaacgttcag gttcaacaag
    15361 cagctaccgc tttttggatt ttactgtttt gctttcctga tctaggtagg atacaagtat
    15421 tgatttttat gggactgatt ttaggttgtt attgggcagt agcttctaac ttaacagtag
    15481 gaatcacgca ggaattgaca gaaggtgccg gatttgcagt ggcacatcag caaatgttcg
    15541 gaatctttat atttgcaaaa ttagctgagt ggatgaaaaa gcgggatgaa aagaaaaata
    15601 gatcaatcaa gcaagacaaa aaaatcgaag atatcaaatt accaggattc ttgtcgattt
    15661 tcaatgagaa tatggttgct acttcgttac tcatgctatt tttctttggg atcattctga
    15721 ttgtactagg caaagattat ttgattcaag cgcaattcat gcaagaagga cagagtttct
    15781 tattctacat tatgacgact tctttaaatt ttgcggtata tctggcgatc ttgcaattag
    15841 gtgttcggac attcgtcgat gaactaactc aatctttcca aggaatctca aacacaattt
    15901 taccaggagc tgttccagga attgacgtag ctgctacttt tggctttggt tcgccaaatg
    15961 cggtaacgat tgggttcttg tttggtgctt tgggacagtt tttgatgatt ggtttactga
    16021 ttttattgaa atcaccaacg atcgtcatag ccggtttcat tccgttgttc tttgataatg
    16081 ccgttatagc agtttatgcc aataaccgag gtggattcaa agccgcttgc ctgttcccgt
    16141 ttctttcagg aatcatacaa gtaggcggtt cagcattatt cgctacatgg attgggatgt
    16201 caacatatgg tggttatatc gggatgttcg actgggcaac agcttggcca ttgtttacag
    16261 taatcatgaa agtcctaggt tatgctggaa ttgccgtagt tgtcattggt ttattggcta
    16321 ttccgcagtt acaatatcgg aaaaatcctg agggttattt tttgattgta gaagactatg
    16381 acacatatgc agaaaagcag agagtataaa agaaaatctg attagacaac actcataatg
    16441 gagggattaa gatgagaatt ttagtatcgt gtgcaaatgg atcaggaaca agcttgatga
    16501 tgatgagaag tgtggaaaaa gcaatgaaag aactaaacgt accaattacc aaaatccatc
    16561 attgtgccat ttcagaggga aaaagttcag ctggccaata cgatgtagtt tttacgccag
    16621 tcaatttttt gaatatgttt actcaggcag agaaaaaaga agttacagtt atcggtatca
    16681 aaaatgtgat gtcagccaaa gaaatcagtg aaaaatttgc tgaaacaaag tggtaccaaa
    16741 aaaacaagta aaggaaggaa ctaagatgag caggccgaat ttgcaaattg cgttagatca
    16801 caatgactta gaacatgcat taggagatgt tatgaaagtt ggtgatgtag tagatattat
    16861 tgaagtgggc acaattcttt gcttacagga aggacaaaaa gcgattcgct gtattcgcag
    16921 tatgttccca gataaaaaac tagtcgctga tacgaaatgt gcagacgctg gaggaacagt
    16981 ggcgagtaat gttgcaaaag caggagcaga ctggatgaca gtcatttgtt gtgcaacgat
    17041 tccaactatg gaggcagcac aaaaagaaat aggtgaattg caagtagaac tctacggcaa
    17101 ttggactttt gaacaagcca tggattggca taacatcggt atccggcagg taatctacca
    17161 tcaaagccgt gatgcgctgt tatctggtga aacttggggt gaaaaagatt tatcgaagat
    17221 caaaaaactg attgaactag gctttaatgt ttctgtaact ggtggattaa atccacacac
    17281 attacactta tttgaaggga tcgatgtgta tacctttatc actggtcgtg gtattacagc
    17341 agcaaatgat ccgatgaagg ccgcacaaaa cttcaaagat gagatcattc gtatctgggg
    17401 gtaaggaaat ggctcaaatt gggatttatg aaaaagcatt acccaaagat atttcatgga
    17461 aagaacgttt ttcccttgta aaagaaatgg acttcgattt tatcgagatg tcgattgatg
    17521 agacggatga gcggttagca cgattagatt ggtctgaaga aaagatagct gagctgagag
    17581 aagagatgtt cagctccggt gtacgtatcc attcgatttg tttaagtgcg catcggcgat
    17641 ttccgtttgg ttctgctgat ccagaaaaga aaaaagcagc gaaacaacta atgaaaaaag
    17701 caatccattt ggcgcataat ctaagcgtca aagtaatcca aatagctgga tacgatgttt
    17761 attatgaaga gaaatcaatg aattccagag aagactttat cgaaggaata aaagaaagcg
    17821 taaaggaagc ttctaaatat ggcatcattc tttccgtgga aatcatggat gatccattta
    17881 tgaactccat ttcaaaattt ttagaaatca aagaacagat tcattcccct tttctacaag
    17941 tatatccaga cctaggcaat ttgtccgcat ggccggaaaa taatccggct cgagaacttg
    18001 agaaagggat cgattatatc actgctatcc acttaaaaga tacttaccct gtaacaaaag
    18061 aatattcagg ccagtttcgt gatgttcctt ttggtagcgg ttgtgttgat tttcttggat
    18121 tattaagaca tttgaaacgt ctagattatg atggaacatt tctgattgaa atgtggagtg
    18181 aaaaaagcca agactttcga agagaaatcc agcaggcaaa agactactta agttctaaat
    18241 tgaaggaggc tggctatgat gtcttgtgaa gaaaaaattg cagcaatgaa gcaacgtgtc
    18301 cttgaagcaa atctggcatt gccgcgatac ggattagtca aattgacttg gggcaatgtg
    18361 agtgaagtgg accgtgagct aggagtcatc gtcattaagc caagcggtgt cagatatgaa
    18421 tgcatgcaag cagatcaaat ggtggtaaca gatttgtcgg gaaatataat agaagaagat
    18481 agcttaaaac catcttcaga tctccccaca catgttgttt tgtatcaaac ttttgaagat
    18541 ataactgcta ttactcatac tcattccacg cactccgtca tgtgggcgca agcaggacgc
    18601 gatttgccag cttatggcac gactcatgct gatgcttttt atggtaaggt tccttgtaca
    18661 cgccaattaa cgaaagaaga agtaagagaa gcttacgaag ttcatacagg gaatgtgatt
    18721 gtcgagacgt ttaaggaaag aaaattagat ccaaacgaag tccctggagt acttgtctat
    18781 ggacatggac cgttcacatg gggggattca cctatgaaag cagtagaaaa cagtttgatc
    18841 ttagatgaaa tttgtctgat ggccaaagaa aacgagctga tcaaccccaa tatatgtgaa
    18901 atcccgcaat atttactaga taaacattat tttcgcaaac atggaaagta tgcatactac
    18961 gggcaataga gatgctaggg taagggtaga aaattaaaag ataacacttg atagagagaa
    19021 acagaggttg tgaagaaaat ttatcacaac ctttttattt atcaaaaagg atgcattcta
    19081 aaaggaaaga gagattttaa ggaatcgaga gaatctttac aggagagtta tatgtgatag
    19141 attaaatagt caaagaactg tattattaga gggagaattg tataagaaag gaagaaaaaa
    19201 atgaatattg attcccttat gatcgatgag atttctgaat tatataagag cgttggttgg
    19261 acgaattaca caaaagacac tgcaaggtta gctagagcat ttgaacaatc tgaatctctg
    19321 ataaagcgta atggggaagg gaagattatc ggaatcgttc gttggatcac tgattttgcg
    19381 acgatcgcat ttattcaaga tatcctcatt catccgaggt atcagcgcca aggaataggc
    19441 aaagtgcttt tgaatgaagc tttggagaag atcactagtt atggaccagt ccaaatcgaa
    19501 ttattgacag atgatactga gaaaacaaaa aaattttatg aatcagtagg atttgttcaa
    19561 gtaaaggaaa tgggtggtat ttcttatgtc atagatacta gaagaaaaaa ggtgcttttt
    19621 ggtaatgaca aataacatat aataacgtac aaaagaaaaa attctagctt agttctttag
    19681 aaaaacaaga ggatagactt agtatcactc aatctatcct ccaatgctca gctattttat
    19741 ttttttactc acctctttat caaatacaat tttttgcaaa ttcgaactaa tataaaaaat
    19801 gaacacatga ttttttttta aagcaaatgc tatgcgataa ttttttttat taattttgac
    19861 tttcatctcg tatattcctt ttgccgaacg agtacgcact ggctttatac gaaaaaaatt
    19921 atgctccaaa tactctgtca ctttgtggga aattgcttct ttatacatga aatgttcttc
    19981 ttgtggaaat tgcttaagta gttcactgtc aaattcaaca gtataatcca tgttttattt
    20041 cctttctata ctgatacatt ataaaaataa acaattttat aagtctctat atttcatgat
    20101 gaatgacaag tatatttgat tcatcttgat atagctctac gagatctcca attccaggat
    20161 acatattgaa ataatcatat ggtatacaaa catttatttt ttttcaattg tcaacactgc
    20221 gtcttcttct tctaattcta taatcttagc aatttgtacg tcgcttttca tgtgtgatct
    20281 tcctttctat acattggatt tacttttcga tgatatctac aacagctttg ccacaagtca
    20341 gttctttttc tagctcgttc tttattttta tggcacatgg tttggaaaaa ggagcagctt
    20401 ctttccatga accaagtaaa ggatattcgt tactgatacc tttcacatat tgtttgtttt
    20461 tgacgccttt tgtttttact tctacataat acatttgatc ctcttctttc ttgctgtttt
    20521 tagttaatat tcaaatatat gtaagtgaaa atgattatgt atctatatct ttatgataaa
    20581 taaaaagaat caatttgaaa gtttttttca ctcgatataa ctaatttgaa taatatatat
    20641 aataaaaggc tattgttctt aaaatataaa tagtatataa agagattgaa ggtaatgctc
    20701 gaatgaacat taccttcaat cttaatgatg cttataacta acgtaataaa aacctgaaac
    20761 aaaaatagct ccgccgatga tatttccaat ataaacgggg ataaaattcg agagaaattc
    20821 taaccaagtc gcttgacctt caaatatggc agcaggtatc acaaaacagt tggccacact
    20881 atgctggaaa ccgattgcca caaaaatcat gactggaaac caaatcgtta gtactttgcc
    20941 ggccgcatct tttgctccat atgataacca taacgctaaa ccgacaaacc aattacaacc
    21001 tattccggag cctaatgctt gccaccaaga aacagcgatt ttatgatcag caatatgaat
    21061 cacttggtcg agatagacac ctgaatgagt taaaccaaca aagtgtccaa agaaataggc
    21121 aacgaaaatt gcaccaataa tatttgcaaa agtaatcact gaccaattct taaccagctg
    21181 tgagaatgtg acttttttat ccataaaggc aatcgccaca gccatcatat ttccggtgat
    21241 caattcacca ccgccaagaa ggatgaccag caggccgata ggaaaaaccg aggcaccaac
    21301 taaactagtc aagctagcca tagattctgg gatagaagca gagactcgta cgtatgccaa
    21361 ataacctaga gaaatcatgg ctcctccgat aaaacctaaa atcagtttag ctaagatagg
    21421 tttatgtatt ttttttgttc caagatgaat actgagttcc ataatttctt ctggtgtgtg
    21481 cataatactt cgattcctac tttcttaatg aattttcatg tgataaaata tagtgaaaaa
    21541 aatcacattt tctttgttga ttatatcatc ttattattta tatgtgcata ttattgtaaa
    21601 attttctatt taatcacatt tgattctaaa aaagaaacaa aaataaaagt catgtatatg
    21661 gtggtcaaaa agtaaataat atcagttatc aaatttcctg taaattttct tgaaactaca
    21721 gcatattatt acttcaaaac aatctacatt ttttataaaa aaggaaatga ataactgaaa
    21781 aaattattat aggagagaaa aaatgtcaaa atctaaaaaa aatatcacca taattggttt
    21841 aggcttaacc gtatatttat ttacagaatt tgtttataga catgtgaatt tatttgcaga
    21901 acctttattt gtattatacg aatcaaattc ctcaatcgtc agtgaacttg ctaatttaat
    21961 gatagcattg ctgtttactc ccgcgttgag agtcataact attttggtct gtttagtgct
    22021 attgtttttt gttaataaaa agaaataacg tagtatttca aaagacaaag aagtgggatg
    22081 atgattgcta tagtatgtta tacgtggtgc taggtaagtg agaataaaca aaaaaggaaa
    22141 cacgcaataa agtttatttc aaaactttat tgcgtgtttc ttttttagat tttttatatc
    22201 tgttgcttta gtagttacca atagttttcg cttaatcaat caaaacgatt ttttgtttat
    22261 tgtattcttt acgaaccttt tcaggaattt cttctgaaat aagataggta aggtcttcaa
    22321 ttggaccgac gatatgatta ctgatggtgc cgaatttatc attagttatc atcccaagta
    22381 cttcagtaga aatacgtatc atctcacgtt taatgtcgga ttcttgcata gttggcacgc
    22441 tcgttccaac atctagatct atgttataaa tacccataat ataaaggtcg gctcgaatgt
    22501 tttgtagttg cttataagct tgtaccccaa tattgatcat agattgttta taaaaagtac
    22561 cgccaatatt gataatttcc aaattaggat gctgtgctaa tgctatggca atcggcgggc
    22621 tattggtaat gattgttgca cgaaaatctt gtgggatttc ttttgctaaa gccaagttag
    22681 ttgtacttcc atcaatgatg atgacagatt cttcttttaa aaaagggagg gctttatgag
    22741 ctaatgcagt tttttgttcg ctagctacag tttctcggta gttaaaattg gtaattggcg
    22801 gaccaacacg taaagcgccg ctgtgtactc tttttaagag accttggcta tccaaatctt
    22861 tcaaatctcg tcgaatcgtg tcttcggata cattgaaacg ttgacttaaa tcactagcga
    22921 taactttttg ttctgcgttt aataaatcta gaattttttg atgacgttct aatttcaaca
    22981 tgttgcgtgc tccttcttat ttattcttgt ttatcatgtc atttatgcgt ttttatgtca
    23041 ataatttccg tttttaatac actaaaaagg cataaacaag caaaaacaaa atatttttat
    23101 gcagttttat gttgactagt atttgttaag cggttacaat gagggggtaa ttaaaggagg
    23161 gaatgtatgg agaaaaaaat tattttgtcg ccttcactta tgtgtgggga tctagcaaat
    23221 ttggaaggaa gcatccaaga actagaaagt attgggatgg attccttgca tattgacgtg
    23281 attgacggtt cttttagtcc cagtatgcct ttagggatcg aaacaatcaa aagaattaga
    23341 gaaatcactt caatgaattt tgatgtacac atcatggcta aggataacga taacgaattt
    23401 tttattggag aaatgttgaa aattggcgta gagagcatta cttttcatta tgaaacaagc
    23461 ctccatattg atcgatatat ccagctcatc aagaattctg gaacaaaagt agggatagct
    23521 ttgaatccag caactccgtt aaatgtatta caatatattt tacccgagat tgataggatt
    23581 tgtttgatgc tgattaatcc aggttttgca acaaacaagt cagaaaaaca agtttcttac
    23641 gcgctaaaaa aaattacaga tctttgccag ttagtaaatg agaaagagtt agcagtagat
    23701 atccaagtgg atggacgggt atcgttagaa acgatcccgg gattattaga tgcaggcgca
    23761 acaaatctgg tattaggaag tacaagtttg tttcttaaag gaaatacatt agcagaaaat
    23821 caaaaactac tttatcaagc gatgaagcaa tcagttagga aaaatcaata gatgtagtgg
    23881 tcctgaataa tagaaatgga ggggaaatag ttgagttata aggcggcgaa acaaaatatt
    23941 gtaagagaaa ttactgaaac attagaccgt atttcttcaa aagatgtgga acaattgata
    24001 aagaaaattg aaaaagcgga acgagttttt ttcgtggggg ttggcagagt actgttagcg
    24061 ctagaaggaa tggcaaaacg cttagggcat ctaggaattc agacagtagt cgtaggacaa
    24121 atcactgaac cggcaattac agataaagat ttattgattg ttggttctgg tagtggggaa
    24181 agtgctttcc cactaactat tgcaaaaaaa gcaaaggaat ttgggtccca agttgcccat
    24241 ataggatcaa acccagacag cacaatgaaa gaatattcag atctttttat tcgtataccc
    24301 gtacaaacaa aattagcgtt accagaggaa atttcttcta tacagccaat gactagcctg
    24361 tttgaacaaa gtgttctttt gttaggagat agtattgctt tagtgatgat agaagaaaaa
    24421 gcaattgata tgtcaaagtt gtggcaatac catgctaact tagagtaggt gaaaaatgaa
    24481 agcggtacat tttggagcag ggaacatcgg cagagggctt attggacaaa ttctacatca
    24541 gaatggattc gatctatgtt ttattgatac gaatcctgaa ctgatccatc aattaaatca
    24601 agataagggt tatactatcg aaattattga tgaaatgaac aggagtgatt tcattgatca
    24661 tgttgtggca ctgaatagtt tatccgagct agaagaggtg attacagcaa caaaaaatgc
    24721 agatatctta acaacatctg ttggcgcaat aaatttagta aaaattgcac cgatcattgc
    24781 gcaagcctta agtaagcgat ttgaacaaaa gcatagcatc aatatcgtag ctaatgaaaa
    24841 tgtgataaat gcaagtgatg tgttgaaaaa agaaatttat tctttgctgt cagaaaaaga
    24901 acaagagaat tttgatgaat atgcatattt tgtgaatacg gcaatcgatc gacaatcttt
    24961 aggaaaagtt cttggaggaa aaatgatctc tgttgtcgaa ccttattatg aatggataat
    25021 ggatcgacag cagttagatc caactacatc ttttgatatg aaaaatgtaa atttggttga
    25081 tgatatggag ccttacattg agcgaaagct ttatatcgtt aatgctgctc atgcggcagt
    25141 agcttattta ggcgcactga aaggatataa gacgattcaa gaagcaatcc aaaatatgga
    25201 gattttcaat ctagtcaagc aatttttaat ggagaatata gagtactttg tacaaaaata
    25261 tcatttttct agagaagaat taacatcttt tgtggaaaaa acattaaacc gtcatgggaa
    25321 tcagaaactc tccgatgaaa ttactcgtgt aggaagttcc cctattcgaa aattaggccc
    25381 taatgatcgt ttaattgctc ccatagtaaa actagattca tatcatttac cttacgatgc
    25441 aggaataaaa gtaattgctg cgggatatca ttatcggaat cttgctgatc cagaagctga
    25501 acaactacgt cgaatgattg taaatgatgg gttgaaagca acgattaaaa agatttctcg
    25561 tttggaaggt aagctgctga atgaagttgt cgctgcttat gagtcccaga tttagaggag
    25621 gagaatatgc taaaagaaca attgtcagga aatacaatgt ttatggatgc gatcgattca
    25681 tggcaagagg caatccgagt aagtgcgcgt cctttgatag gaaagggaat aatagaggaa
    25741 agctatgtac aagcgatgat acaaaatgtg ttggataacg gaaattatat tatattactg
    25801 ccactagtag caatgcctca tgcgcgtcca gaatttggga gcaaaggggt cgggatgagc
    25861 tttttatgtt tagataagcc agtcatgttc ccaagtgaag aaccagtaaa attcttcttt
    25921 accttttctt ctgattcgcc aaagggacat ttagacttaa tggccaatct tggagaattg
    25981 ctgagtgatg aaaaaatgta tcaaaaatta ttcgatgtga agacagaaaa agcattgtta
    26041 gatttgataa agaagtaaag gagagaagaa aatggaggta gcaaacaaaa aaaaacgagt
    26101 ctccatgcga gctaaagttc aagcgattgg cggtttctta acaaatatgg tattgccaaa
    26161 tataggcgca tttattgcat ggggaattgt tactgcatta ttcattccaa ctgggtggtt
    26221 cccaaatgaa tctctgaatg aactcgtaag tccgacagtc agctatctat tgccgttact
    26281 acttgcctat actggtggtc ggatggttgg tggtacacgt ggagctgttt taggtacaat
    26341 cggaacaata ggtttgatta ttggtgctga cataccaatg ttcatgggag caatgattat
    26401 ggggccactt ggtgggtgga tgatgaaaaa aacagatgat tttttagatg ggaaagttcc
    26461 tgctggtttt gaaatggtcg tcaataattt ttctatagga attattggtt tcatactgat
    26521 gtgcctttct tatctggtag ttggaccaat aatccaatca gctaatcaat ttgtaacgag
    26581 tgcaattgaa gcattagttt caactggttt tttaccgata ctgtccttaa tcaacgaacc
    26641 ggcaaaagtc ttatttttaa ataatgttat tgaccaaggt gtttattatc cattaggtat
    26701 gcaacaaaca ttagaggcag gcagatcaat ttatttcatg gtagcatcaa atcctggccc
    26761 tggcttagga ctattgttag cttattcttt atttggtaaa aaggcagcaa aacagacagc
    26821 accaggtgca atcatcatcc attttttcgg cggaatacat gagatttatt ttccatatgt
    26881 attaatgaaa ccactcacta tattatctat gattgctggt ggaatgacag gaatcatcac
    26941 ttttgaatta tttgatgcgg gcctggtagc aggtccaagt ccaggttcta ttttttctta
    27001 tttagctcta acgcctcggg gaaatttttt gggtgtcatg gcgggagtgg tcacagcaac
    27061 actggtttcc ttttttgtaa catcagtaat tttaaaagca gataaatcaa cagatgaaga
    27121 cagaaatttt gaactatcag ttcaaaaatc gaaaacgatg aaatcagaag gaagaaaatt
    27181 attaaaagaa gaaaatgcta gagaaatatg taccgagaaa aaagagatga ataaaatttc
    27241 ctttgcttgt gatgcaggaa tgggaagcag cgcaatgggc gcaacaatat tcaagaaaaa
    27301 attgcaaaaa gcaggtatta ctgatgttga gataaaaaat tatcgaattg aagaggtacc
    27361 agaagatagt gatttggtga tcgtacatca agatttggag gaacggacta gaaaagcaca
    27421 tcctaacatg aaaattgtga cattaaagaa ttatttgcaa gatccagtaa tcaatggatt
    27481 agcagaagaa atcattggat taaaaacaga agactaattt atgggaattt ttgattaacc
    27541 tttattaaaa ttattttgcc taatataaaa aggttgtgac atggcttgtg tcgcaac
//
LOCUS       DAXLPY010000031        27519 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.031, whole genome shotgun sequence.
ACCESSION   DAXLPY010000031 DAXLPY010000000
VERSION     DAXLPY010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.031"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..660
                     /locus_tag="ACF3UF_001475"
     CDS             <1..660
                     /locus_tag="ACF3UF_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFD3671600.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIREWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
     gene            822..1010
                     /locus_tag="ACF3UF_001476"
                     /pseudo
     CDS             822..1010
                     /locus_tag="ACF3UF_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
     gene            1287..3347
                     /locus_tag="ACF3UF_001477"
     CDS             1287..3347
                     /locus_tag="ACF3UF_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFD3671601.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            3430..3999
                     /locus_tag="ACF3UF_001478"
     CDS             3430..3999
                     /locus_tag="ACF3UF_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3671602.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4174..4980)
                     /locus_tag="ACF3UF_001479"
     CDS             complement(4174..4980)
                     /locus_tag="ACF3UF_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671603.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5119..6633
                     /locus_tag="ACF3UF_001480"
     CDS             5119..6633
                     /locus_tag="ACF3UF_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFD3671604.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(7036..8019)
                     /locus_tag="ACF3UF_001481"
     CDS             complement(7036..8019)
                     /locus_tag="ACF3UF_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFD3671605.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(8024..8671)
                     /locus_tag="ACF3UF_001482"
     CDS             complement(8024..8671)
                     /locus_tag="ACF3UF_001482"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFD3671606.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(8756..9388)
                     /locus_tag="ACF3UF_001483"
     CDS             complement(8756..9388)
                     /locus_tag="ACF3UF_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3671607.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(9404..9955)
                     /gene="coaC"
                     /locus_tag="ACF3UF_001484"
     CDS             complement(9404..9955)
                     /gene="coaC"
                     /locus_tag="ACF3UF_001484"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFD3671608.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(9952..10689)
                     /locus_tag="ACF3UF_001485"
     CDS             complement(9952..10689)
                     /locus_tag="ACF3UF_001485"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFD3671609.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(10686..11675)
                     /locus_tag="ACF3UF_001486"
     CDS             complement(10686..11675)
                     /locus_tag="ACF3UF_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFD3671610.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            11933..12475
                     /locus_tag="ACF3UF_001487"
     CDS             11933..12475
                     /locus_tag="ACF3UF_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFD3671611.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            12492..13577
                     /locus_tag="ACF3UF_001488"
     CDS             12492..13577
                     /locus_tag="ACF3UF_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671612.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            13589..14395
                     /locus_tag="ACF3UF_001489"
     CDS             13589..14395
                     /locus_tag="ACF3UF_001489"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671613.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            14396..15223
                     /locus_tag="ACF3UF_001490"
     CDS             14396..15223
                     /locus_tag="ACF3UF_001490"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671614.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            15220..16293
                     /locus_tag="ACF3UF_001491"
     CDS             15220..16293
                     /locus_tag="ACF3UF_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3671615.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            16721..19417
                     /locus_tag="ACF3UF_001492"
     CDS             16721..19417
                     /locus_tag="ACF3UF_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3671616.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            19482..19982
                     /locus_tag="ACF3UF_001493"
     CDS             19482..19982
                     /locus_tag="ACF3UF_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3671617.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            19994..20488
                     /locus_tag="ACF3UF_001494"
     CDS             19994..20488
                     /locus_tag="ACF3UF_001494"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3671618.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            20509..21318
                     /locus_tag="ACF3UF_001495"
     CDS             20509..21318
                     /locus_tag="ACF3UF_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3671619.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            21315..22136
                     /locus_tag="ACF3UF_001496"
     CDS             21315..22136
                     /locus_tag="ACF3UF_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3671620.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            22187..24286
                     /locus_tag="ACF3UF_001497"
     CDS             22187..24286
                     /locus_tag="ACF3UF_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFD3671621.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            24283..25401
                     /locus_tag="ACF3UF_001498"
     CDS             24283..25401
                     /locus_tag="ACF3UF_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFD3671622.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            25440..26318
                     /locus_tag="ACF3UF_001499"
     CDS             25440..26318
                     /locus_tag="ACF3UF_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3671623.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            26464..26661
                     /locus_tag="ACF3UF_001500"
     CDS             26464..26661
                     /locus_tag="ACF3UF_001500"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFD3671624.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            26645..26875
                     /locus_tag="ACF3UF_001501"
     CDS             26645..26875
                     /locus_tag="ACF3UF_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671625.1"
                     /translation="MNFFGDRFFQPYKINRNSIIESCDYKKIARKKKKVSIHFKYFIP
                     ISIAKKVEILYLPLTLASLANVVSILIDNKLR"
     gene            27120..27311
                     /locus_tag="ACF3UF_001502"
     CDS             27120..27311
                     /locus_tag="ACF3UF_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671626.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
BASE COUNT         8784 a         4732 c         5745 g         8258 t
ORIGIN      
        1 tatatttctt tgttatgcaa agaagaagtt cgcgaactac ctaaatctaa ttctgctgtt
       61 ggtattgacc taggtattat agactttgca attctttctg atggacaaaa aattgataat
      121 aataaattta cgtccaaaat ggaaaagaaa ctcaaacgtg aacaacgtaa gttgtcaaga
      181 cgtgccttat tagctaaaca aaaaggtatc aatctgtttg aagctagaaa ttatcaaaca
      241 caaaaacgta aagtagcacg attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat tatcaaaaat cacgatatca tctgtattga agacttaaac
      361 acaaaaggca tgttgcgtaa tcataaacta gcaaaaagta tttcggatgt ttcttggtct
      421 agttttgtgt ctaaattaca atacaaggct gactggtacg gtcggaaaat catcaaagta
      481 gataagtggt ttccatctag ccaaatctgt tcgaattgtg gacataaaga cggcaagaaa
      541 tctctcgaaa ttcgagaatg gacttgccct atttgtcata ctcatcatga ccgagatatc
      601 aacgctagta tcaatatcct gaccgaaggt ctaaggctac actctatggg attggcttag
      661 atcaaataaa caagaaccgt aggaactacg gggatagctt ggtaaataag aggcacctct
      721 gttagtaaag taatacgcta tcaagtatgc tctcttccca agaagctccc acttcaagcg
      781 taagaaaccg ttaggtttag ctaagtggtg agtagttcac aaattacaat attgtgattg
      841 agagtcgaat cacttctcgt acgaatattt atttatctga ttgtttactt gaaaaattta
      901 ataaagaaca gataatttgg aaaaatccac cgactccaga tgactgggaa tattttggaa
      961 ataccatcat cagagaaaaa aatagacatt taactgaaaa aatcagctag tatttatgga
     1021 tggcagcttt gtctcacata tttattagct gatttatgtt tttttcaaag aaaaggtaac
     1081 tagatataac tagatataac tagatatatt acttaacaaa attaaaaagt acataagtta
     1141 ttattccgat tttcttgaaa caataaaaaa tcaaaaaaaa tactctccta atagtccatc
     1201 ttcttttgat tttatttata taatgaaatc atcttatgaa aattactact tcatgtttag
     1261 acaagagtag ggaggactaa gaataaatgt gttcaaaaag acgttcaaaa caactaaata
     1321 aacacgcttg tcgtttagat aaggaacggt cgtgttctga aaaacactac gttaagttta
     1381 tgatgcgcac gatgctgatc agtttatctg taggtgtcta tatgcatgta cccgttcagg
     1441 caacgacaca aaccatcaag gtcgtacgta cctctgtttc tgagaccact gattccccta
     1501 tcactattac tcatactttc actgatgcaa atggaaaaca gctacttcct gcattgactt
     1561 cctataataa agtcagttat cctccaacga taaaccacta ctggttaatt cctaacaaaa
     1621 cattatggac atcggaaacc ggaagcagtg tgccgctttc tatcttttcc gatatgactg
     1681 atcctacaaa aggtgatcag ttaaaacaga tcactgatat tttgaatcat gctttgacag
     1741 atataaagga cggtggaagc gcacaagttt cttatgtata tgaaaaagat tattcacagt
     1801 ttgaaagaaa gaaaatcgat gttctggcag ggacaaaagt ttcgatatct gatctggtag
     1861 aaaggctgaa gaacgcagat ggaacacaag gagatatgtc caaagtaatt tcaaacaatg
     1921 ggaatatcgt ggatacgact aatacaggaa catctactat ttccttgtcc tattttgatc
     1981 caattgcttt aaaaacaatg actgcatctg ctgtgatcca tgttcgtgct gatcaaacag
     2041 ctatcaaagg aaaagatctt cacttaagaa caggagagag ttacgcccct aaagatcttg
     2101 ttgaatatgt aacaaaaagc gatggaactt caggaaataa agaagaaatc aaaatgaacg
     2161 ggacagtaga tactacaact ccgggagaat atcccgttgt attaacttat atagactcga
     2221 aaacatcaaa tgtggcagaa acaacagctg tagtttatgt agaagcatct gctgcttcat
     2281 cgactgtcat cactcatttt atagatagtc aaacaaataa agaacttcaa gcagaaacac
     2341 atatgagtag tgtaaatcgt attcctgatt tgcgcctacc tgctgaattt tctgatcgag
     2401 tgccaaatat agatttatcg acttatgaac aaaatgggaa agtcacttct atttctgatt
     2461 ggatgcaagc aaacggatta gacagaaaaa gtcactggtc ggagatcctt gaagtacttc
     2521 actcagaact gatgaataat aggaagcaat caggagggga aattaccttt acttatgttt
     2581 atataccaga caatcgttca ttagaaggtc atgatcttat tgttcatcca aacgaaaaaa
     2641 taaacaaaga agagttgatc caatcagcaa caaattcctt aggtaaaccc gtaccgttaa
     2701 aggatgtatc ggttacaatc aatgaagtac cattggagga tggttatttg accaaacaaa
     2761 caggtgattt tacgattatg tatagttatc atgacccgta ttcactccaa gaactccatg
     2821 ctcagtcact attacatgtt ttaccattaa acaaacagat agatcaaaaa gaacaaaaaa
     2881 gacaagaaga aagcttgtca gaaaaaaaac aacaaatggc ccatgcagtt tctccaacag
     2941 ggaaagtaaa acaaacaaga agcctagagt tagcaagaat atctagaaaa atctcagaat
     3001 ctaataaaac gataaggcaa gaagctcatt tggccccaca agtttctgga ttggaaaatg
     3061 aaattttaga gcctaaaata aaacaacaat cagaaaaaga atttgttgct aaacagtcgg
     3121 aagatcagaa ggaatcagat gaccagaagg aaacgaagaa aaaacgcttg tcaactattg
     3181 attccaccga tgagcatctg cagccgcaag taccacttcc tagtccggga acacccgcac
     3241 ctggtggagg tattccttct tctgctttag gagatttcat gcgaggtatg gcaggaacat
     3301 gggtatacgc taatcgaaat gaatttgacg cagatgactg gttctgattt atatctctat
     3361 ctgttatagt caaataagta gctgagtcat atgttatttg gcataatgga gacgaggagg
     3421 gatagaaaaa tgttagataa aacgttacct tacgcagaaa tctggatgac aagaccactt
     3481 caacaaaatg ttccaatcac gcctttagcg gaaggttttg aatttcgatt ttatcaaaaa
     3541 gaagatgaat ctgcttgggc ggagattgag acttccgttg gggaatttca aacgacagat
     3601 gaagcacttg agtattttca acaaaacttt gctccttatc ctgaagaact tgaaagaagg
     3661 atgttttttg tagagacaaa aaaaggagaa aaagtagcaa cctgtaccgc ttggcgaaaa
     3721 aaatcaagag agcaagtgta tccggttttt cattggttag cagtgaaacc agattaccaa
     3781 ggaaaagggc tcgcaaaagc attgactgcc agagtcttgc aagaatttcc taccctccat
     3841 acggacggac caatctatct tcacacacag acatggagcc atcaggcgat tgctctttat
     3901 aaaaaaatgg gttttacttt tattgctgaa aatctagacg gcacacctaa tccagattat
     3961 gaaaaagtta tgcaggtttt aagtaaatta gataaataac gaaatggtga aataagtcct
     4021 cagtattggg ataaaaaacg aaatagtcat tcctcatatc ttactttttt gagttaatac
     4081 tatcggataa ctaatggcat gccatacatt caaaaaagaa ggggcagtga caaaagtatt
     4141 gtcactgccc cttctcttgt tttttagcat gttttatcgt ttgatttttt taggaataaa
     4201 attcttgatg aacgtaaatt tttggtaatc gtttcgacta tagaggtaac caaatacact
     4261 gaaaacaact gctccaataa aattaacaaa taaatccttc atagtatcca tgattcccac
     4321 gtctaagtaa ccattttgga tgattgtttt atctgtttta ccatctgcat tttgactttc
     4381 aatgattgtc cgagtgatat ctggaacatg atagacagtg tttccgtctt tacttaactc
     4441 cacactattg atttgctgga tgatcgtatc tttttgcata tcgaattgca gtaatttatc
     4501 tgctgaaaat tccacaaact cccacataac accaactgtc atcgaaaaac agaaggaaac
     4561 aactgctagt aataaaggag tcaagttcat ggtttttgta tttttattga gcaaataaac
     4621 aagggaaaag ccgacacccc cagctaaaaa tccgctgaat gcatgtagaa aagtatccca
     4681 cattgaaaaa tagccataaa aatcacttaa ctctcctaaa actgttgaac taaaaataaa
     4741 agataacaaa atgatttcta gcatatttgg aatctgtatc tttaatatct tttccagaaa
     4801 ataagggatt tcaaataaaa ttaatgtcag taataaaagc attgtatttc cccagtgttg
     4861 gttccagacc tgatccacta gcataataac gacgatgata cgtaataaaa tatagattcc
     4921 gtttgtgatt ctacctgcag tttttgtact gttcgtaaaa aaggttttca aatgattcat
     4981 aaaataactc cttcatgtat atccttaatt atactaagaa gcgtgtgttt accaaagcta
     5041 tatgacttaa agaaaaacag agttgatatt gtgaaaaaaa tcacttaata tagtataagg
     5101 agaaaagggg ggatacaaat gaaaaaatta gttgctggtt tattaacagc cgttgcactt
     5161 cttgctatga gcgcatgcgg cgcagatcag aaaaatacag cgcagacaag ttctagtacg
     5221 aaggaatctg ccgaagtatc atcaggcgct tctgaacaag tatatacaga tccaaaagaa
     5281 atgaaagaat cttatgatgt cgtgattatt ggagctggtg gtgcagggat ggcagcagct
     5341 atcgaagcaa aagatgctgg gttgaatcca gtaattttgg aaaagatgcc tgttgccgga
     5401 ggaaacacat ctaaatcatc aagcggtatg aatgcttcag aaacaaaatt tcaaaaagaa
     5461 gaaggaatca aagactcgaa tgatgccttc tatgaagaaa cgctaaaagg tggtggagga
     5521 acgaatgata aagaaatgct tcgatacttt gtcgatcact ctgctgatgc ggtcgattgg
     5581 ctagatcaaa acggtatcaa actggacaac ttaacgatca ctggagggat gagtgaaaag
     5641 aggacacatc gtccgtctga tggctcggct attggtggat acttagtgga ggggttattg
     5701 aataacgtcc atgagcggga aatccctatt tttgtcaacg cagatgtgac agacattaag
     5761 aaaaatgggg aaacggtcaa tgaagtgact gtacatgttc aaggagaaga accaaaagag
     5821 gtcaccggaa aagcaatcgt agttaccaca ggcggttttg gtgccagcaa agaatttatt
     5881 gaaaaatatc gtcccgattt agctgattat attacgacaa atcaagaagg atcaactgga
     5941 gatggtatca ccatgattga aaaattaggt ggacaaaccg ttgatatgga taaaatacaa
     6001 attcatccaa ctgtgcagca ggatgagggg gtcttgattg gtgaggttgt tcgcggagaa
     6061 ggagcaatct tggtcgatca agaggggaaa agatttgtca atgaaatgga tacaagggat
     6121 aaagtatctg cagcaattac agcattgcct gaaaaatcag cttatttgat ttttgaccaa
     6181 ggcgtgcgtg atcgtgccac agctattgaa ttttatgacc aaaaaggata tgtcacaact
     6241 ggaaagacaa tggaagaatt agcagaaaaa atcgatttac caaaagaaac actagcaaaa
     6301 acagttgatg gatggaatac ggatgttgcg gagaaaaaag atgctcaatt caaccgtgcc
     6361 acagccatgg aacatgactt atcgtctccg aattattatg cgatcaaaat cgcaccagga
     6421 atccattaca cgatgggcgg tgtgaaaatc aatacgaaca ctgaagtatt agataaagaa
     6481 aaccagccaa ttagggggtt atatgctgct ggtgaagtca caggtggctt acatggaaac
     6541 aaccggatcg gtggaaattc agttgcggag atcattattt ttgggcgaca agcgggcata
     6601 caagcagctc gatttgcttc ggaaaatgaa tgaaatagaa cgtaaataaa aagaggttgt
     6661 gaaatcagcg ttttgagcta ataccgaggg tcagctgatt gaacactgtt tagtgaagag
     6721 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta
     6781 tgtttttaac ttggttggac ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6841 gaaaaagagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa acacgtataa
     6901 acggcggaag cagaagaaat tccttcggaa ataagctgaa attcacaaaa atttgaaaag
     6961 caattttcgt gaatttcttc ttatttcttg gagttaaacg cttctgtccc agcctctttt
     7021 ttgatcagca tgattttatt cagttatctt caaaatgatt tttccgatgt ttttgtttgc
     7081 ttccatatat tcatgcgctt gtttgactgc gctgaattgg aatgtacggt caatgattgg
     7141 ccgaatcttg ccattttcta gaaaaggccc agctttttgc ataaaagttt gtgcgagctc
     7201 tgctttatac tgatcacttc taggtgtcaa taatgtacca agcagttgga cacgtttccc
     7261 aatcaataca ccaaggtcta tctcaggcac gatggtccca cctagcatac caatcaagac
     7321 ccaacgtcca tcaacggcta tagaagctaa attcttttcc cagtaagaag cgccgatgaa
     7381 atccaaaata acatcgactc cccgaccttc agtgattttt cgtacctctt cttgaaagtc
     7441 ttgtttttta tagttgatca attcatctgc accaagttct ttacaaaagg cgagtttttc
     7501 ttctgatcct gcagtaacga tgattttcgc gtgagaaagc tgtctagcta attggatcgc
     7561 tgctgttccc acaccacttg ctcctgcatg gatcaagaca gtttcgcctt cttgtaattt
     7621 tccaagccag taaagtgttt gataagcagt caaaaaaact tctgagattc cagcagcaga
     7681 aacatagtct agcgtatcag ggagaaggat tgcacgatcg gcaggcatca cagcatattc
     7741 ggcataacca cctagattga ctaatccgta tacttttgtc ccaggagtaa aagtggagat
     7801 atcactttta ttctcaacta cctctccagc tacttcgact cccaaaatag ggtagggagg
     7861 tttcaaagag actgattctc ttttcataat atctgttcga ttgacagctg ctgtatggac
     7921 tttgatcagt aattcgcctt gttttggttt aggaacaggc acttcaattt gttctaatac
     7981 atctacagaa ccaggatgct tgattgaaat ggcacgcatg gatctattcc tcctttgccc
     8041 attcttggaa tgctgtattc aactctttgc taccttcaga aagtactaga gtcgtacgag
     8101 aaatatccgt ttcttccact agagcggcaa gtacagcagc aactgtagag cgagtgatcg
     8161 tttttgatgc cttctcatta ggcttagtta attgaatgga agtaacttct tcatcgttag
     8221 tcaatgtgac tggttgaaga atgacaaaat ctaagttagt tcgtttcagc cattcatctg
     8281 cataatgttt agtaatataa taatctgtca tggactcagg ccattttgct ggttcatctg
     8341 cataaacagc actgaccatc agatagcgag agacatgcgc attttcagct gcgatcactg
     8401 ttttgattgc gccatccaag tctacttgca gaagattctt tccttgagag ccggcagcaa
     8461 aaatcaatac atcgatgcct ttgaatgctt cggtcatttt ttccacggac caagttaaat
     8521 caaaagagac atacgaaaca ttctcttttt ttactaatgt ttgggaagca acatctctca
     8581 cccctgcaaa aatttcatgg gaacttggag ctaaatcttt tatcaggtgt cggccaattt
     8641 gtccgtttgc acctacaaca aaaattttca tttggatcat cctttcgacg tcaaatcttt
     8701 ccattcaata gtaacaccaa aagagaaaaa aatcagagat cggctacgat gactatcagt
     8761 tagtaagaga agggtgcttg aagtatctta acaagacatt gcatactgct gcagtcgcaa
     8821 gacctgcgac gattccttca ggtataccac ttgtaaaaat aaccgctaga atagctgaat
     8881 aaacagcatt taaatttgtt ccgatgactt tggcataatc ttgctggaat aaaaagtaga
     8941 tcatattcat cactaaaatc gtattggtca atgaaccgga aagtccagct aagaataaag
     9001 aaacggaatc tgctttttgt ttcattagtt tgcgcagacc tttataaacg aaataaggaa
     9061 ccaccccaat caagatgcga ggaataaacg cgatcagcaa ggctttccag cttccatgtt
     9121 ctgttccgat gactgggata aacggagaaa agacaaaaga caaaggtgtt tggataactg
     9181 tgctacggat catgctgatc agtccaaatg taccgccaag aaaagcacct agtcttggtc
     9241 ctaaaacgat cgaagcaatg attacaggaa tatgcatggt tgttgcattg attggaccga
     9301 tagggataaa acctaaaggc gtaacagcta ataaaatcaa aatagctaaa aacatcgcag
     9361 ttaatgtaaa gttttttgta tttttcataa gtactccttt tttctaagca tttctttcat
     9421 taagagtcag catgacctgt tcgatgatcg tctgaatatc agctaaggca ccttttccaa
     9481 aatctccaca agctaaaaga gattctcttg gttcaatttc ctgatagccg acagatctca
     9541 atgtttccag attacgctga gtgatcgggt tttgatacat attcgtgttc atggcagggg
     9601 caatcaattt tggtgttccc actggaagcg ccattgcgac tgttgaaaga agatcgtctg
     9661 caatgccgtt tgctagcttg ccgataatgt ttgctgtagc aggcgcgatg agaaacaagt
     9721 cagcttgttt tgctagttcg atatgattga ttacctgcgg atttgattct tgcatgacgt
     9781 ctgtatggac tgcgcgcttc gacagagatt gcaaggttaa tggcgtgata aaatgtgtgc
     9841 tgcttttaga cataatcaca tctacctggg cacctaattt gacgaattga cttgtaagat
     9901 cagcgctttt gtaagcagaa atacttccag taacgcctag taagatcttt ttcattttga
     9961 ttcctccagt ctaattttct cagtaatcaa tgcagcaatc tcagatttac tttgagcttc
    10021 ttccactgtt ccatctttag ataagagata gccgtggtgt gtctcgccat ggatttccgt
    10081 caaatcattt gcgaaaataa aatcagtttt gttatttatc agactatttt ttgcgactgc
    10141 cagaagagat tcctttggta catctactaa tagtttgaaa ccaatgattt ttgcttttgg
    10201 ctgccattca cgtagataag aaatgatttt tggtgttttc ttcaaaacga gcacaagatg
    10261 ctcggtgtta gaagagatct ttgaaacagt ggtatctgtc tgttcatttt ccgcaaacca
    10321 attgtccagt tcttcttgcg ttgaagaagt gggtaggttt tttgccagct gttcttctga
    10381 aaaactaaaa gcaggagtaa aatcactgac tgccatactg tggataatcg catcgtagtg
    10441 ttcttttttc gttagttctt ctaattgtaa aaataagtcc agtgcagatt cgatcgtata
    10501 aatcgttata ttggagtgtc ttttcggttt cagtgcttgt ttcgtagtca cgtaatcgat
    10561 tgtggtatcc ggattggcag ctaaataatc agctaatgct tgccctaatc gtcctgtcga
    10621 atgatttgta atagcacgta cttgatcgat tttttcagtc gttcctccag ctgtgattag
    10681 aatcttcatt tatggtcacc tacatttact agtgttcttc cttggtgtgt tccagcaagt
    10741 agtttagatg ctgtttcagg caattgatcc agagtaatct cttggacgac cagttcatct
    10801 gcaatctgca aatccgccat ctgttgccat aaagaaagac gttgatctat tggtacattg
    10861 acagaatcaa ttccaatcaa ctggatgttt cgcagaataa aaggcaagac agtcgcgttt
    10921 agtttgattc ccccagcatt gccacataaa gctactgcac cgttataaga gatcaatgga
    10981 agaagactgc ttagctgctc gccacctact gtgtcgatga catagtcgat ttgctgtttt
    11041 cctaaagctt ttgttgtctc tggcagaaat tcatcaggtc gtacgacttg caaagcacct
    11101 agacttttta gccatgtgac agactcttct tttctggaaa aggcaatgat tgactggaat
    11161 cctagtttat gtaacagggc tatcgctgta ctgcctacac cgccagaagc accagtaacg
    11221 acaacttttt tatcggaggt cataccttga cggattaaag cgttcacaca caacatagca
    11281 gtaaaccctg ctgtaccaag gatcatcgct tgacgcagcg tcatattttt tggtagagga
    11341 actaaccagt ctcctggtac tttttgatat tggctataac cgcctggatg ggtgacgcca
    11401 agcccaaaac cagtagcaag tacaagatct tcttttgaaa aacgtggatt gttactttgg
    11461 acgacagttc cggataaatc aatccctgga gtcatcggat atgttcgtat cacctgacca
    11521 gactcgctca ttgccaatgc atctttataa ttgacatcag aataggcaat ttttaccaag
    11581 acttcatttt cagccaactc agtaaatggc agatcactga ttgctgtatg gaaaacaggt
    11641 tcctttatta cctgaaaaga tcgaaaagcg ttcattcgtg agacactcct tttaaaattt
    11701 tcttttatca taccataaag cctactcttt tattcttgtt cttccgtaaa tttagacaaa
    11761 aattaggtga aaaataaaga atcaaacaac tagaatttat tccaaaagat aaagaaatat
    11821 tcagcaaaaa aaattttaca aatggttgcc tttttcaata aatttcgtat actaatacga
    11881 gtggtagtaa acaggaagtt tactattaga aaacttcgat tcggaggaaa ttatggaaat
    11941 tggtgagaag ttaagaaatt tgcgcatcca aaagaatttg acacaagaag aactaggcga
    12001 acgcacagat ttgtcaaaag ggtatatttc ccagttggaa cgagatttaa gttcaccatc
    12061 aatggaaaca ttcttttcta ttcttgaagt cttaggtgtg actccagaag aattttttca
    12121 tcaagaagca gcgaatctgc aagtggttta ttcaaaagaa gatcatacgg tttatttcga
    12181 tgaagaaaac gggtatgaat tggaatggct cgtggctgat tcgaatgaaa aagaaatgga
    12241 gcctgtcttg ctgacttttg aaggtgcagg agaatataag acgtttgaac cttcattatc
    12301 tgaaacgttt atttttgtat tagaagggga attagagtta agcttaggag agacggtcta
    12361 tgtggcaaaa gcaggacagt cgatctatta tcaagcgaca aaacaacatc aattaaggaa
    12421 tcatctcaaa aaacgaacaa aagtattgat tgttgcaacg caatcatatt tgtaatatag
    12481 ggggtaaaaa cgtggggaaa ccaatcattt catttgatca agtagtgaaa cgctatgatg
    12541 atgaaacagt attaaaaaaa gtaagttttg agatcgaaca aggaaaattt tatacactgc
    12601 ttggtccttc cggctgtggt aaaacaacga tcctacgtat tatagctgga ttcaccgaag
    12661 ctacagaagg ggacatctat tttgaaggga aacggttgaa tgatttgcca gctaataagc
    12721 gacaagtaaa tacagtcttc caagattatg cactttttcc tcatatgaat gtttttgata
    12781 acgttgcttt tggattgaag atcaagaaaa tgtccaaatc agatatcgaa aagaaggtaa
    12841 aagatgcttt gcgtatggtc cagcttcctg gatacgaaaa acgggagatt agtgaaatgt
    12901 ctggtggtca aagacagcgt gtagcgattg cacgagcaat tgtaaatgaa ccgaaagtat
    12961 tgctattaga tgaaccgtta tcggcgcttg atttgaaact acgtacagat atgcagtatg
    13021 aactgcggga tctgcaacaa cgattaggaa tcacgtttat ttttgttact catgaccaag
    13081 aagaagcgtt ggcaatgagt gatgagattt ttgtcatgaa taaagggaaa atcgtccaaa
    13141 gtggtacacc cgtagatatt tatgatgagc caatcaatca tttcgttgct gattttgttg
    13201 gggagagcaa tatcgtggac ggtgtaatga tcgaagataa tctagttgag tttgttggta
    13261 agcaatttga atgtgtcgat ggcgggatgc gtctaaatga accagttgaa gttgttttac
    13321 gcccagagga tttgacgatc acgacaccag ataaaggaaa actagtcgta acggtcgata
    13381 ctcagctgtt tcgtggtgtc cattatgaaa tcatctgtta tgatgaacag caaaatgaat
    13441 ggatggtcca ttcaacgaaa aaagctaaag aaggaagcaa agtaggattg gcctttgagc
    13501 cagaagatat ccatgtcatg cgtttcaacg agtctgaaga agaattcgat gcacgtcttg
    13561 acagctacga agaatagggg ggacaagaat gaaaacaatg cgcaggatct attccgtccc
    13621 ttatattttg tggctcggtt tattcgtgat cgcgcctgta ttaatgatca tttatcaatc
    13681 tttttttgat atgaatgggc aattcacgct gaataattat ctatcttatt ttacgtcggg
    13741 gacatcgctt tctatgacga tcaattctgt atggtatgca tttttgatca cgtttttcac
    13801 gctgatcatc agttacccga ctgcttattt tttaacaaaa ctgaagcaca agcaattatg
    13861 gctgatgctg attattttgc ctacatgggt gaatctgctg cttaaagctt acgcatttat
    13921 tgggattttc agtgtgcacg gcagcgtgaa tcatttcttt gattttatcg ggatcgggcc
    13981 gaaacagata ttattcacag acttcagttt tctgttcgtg gcaacgtata tcgagattcc
    14041 atttatgatt atgccaattt tcaatgcatt ggaagagatg aatccttctt tgatcagtgc
    14101 tagtagagat ttaggcgcga atagctttga gaccttccga cgagtgattt ttccgttatc
    14161 attaaatggt gtgaaaagtg gtgtccaagc agtatttatt ccttctcttt ctttattcat
    14221 gctgactcgt ctgattggcg gaaatcgggt gatcacttta ggaacggcta tcgaacagca
    14281 tttcttggtt acacaaaact gggggatggg ttctacaatc ggtgtgattt taatcattgc
    14341 tatgttcatc gtgatgctcc tgacaggcga gaagaaaaaa ggaggtcgct cataaatgaa
    14401 aaaatttaaa tggtcgtatc tttatttagg gatcgtcttt ttattcttat atgcaccgat
    14461 cttctatctg attttttatt ccttcaatga aggaggaacg atgaacagct ttacaggatt
    14521 tacttgggaa aattatgaag ctgtttttga agatacacgt ttgatcatta tcgtattgaa
    14581 tacgttcatg ctggctttct tatctgcatt gatcgccacg atcatcggga catttggggc
    14641 tatgggaatc tattacacga aaaaacgacg tgcacggaca gcgttgttga gcatgaataa
    14701 catcttatta gtctctcctg atgttattat cggtgctagt ttcttgattt tctttacact
    14761 actaggattc ggattaggtt ttcagagtgt attgctttcc catattgctt tcagcattcc
    14821 aatcgtcgtc ttgatggtct tgccaaaatt gcaggaaatg aacgattcaa tggtcgatgc
    14881 ggctagagac cttggtgcta ataatttcca agtagtcaaa aatatcattt tgccttatct
    14941 ttctccagga atcatagctg gatattttat ggcatttacc tattctcttg atgattttgc
    15001 ggttacattt ttcgtcacag gaaatggctt tacgacgctc tcagtagaga tctattctcg
    15061 tgcaagacaa ggaatcagtt tagaaatcaa tgcgctaagt gcgttagttt tcttgttctc
    15121 catgatattg gtcattggat actactttat tagtaaagaa aaccgtccaa aacggctgaa
    15181 gaaaaacaga agagtacgcg agggggtggc acggctgcga tgaaaaaatt acaatctctg
    15241 tttttaggta ttctcatcat tattgcggtg ctgctgcttg gtgttcgtca acttgaaaaa
    15301 acaagtggca tgagtggagc aaaggtactt accatctata actggggaga ttatatcgat
    15361 cctagtttga tcacgaaatt tgaaaaagaa tatggataca aagtgaatta tgaaacattt
    15421 gattctaatg aagcgatgtt cacaaaaatc cagcaaggtg ggacaaacta cgacatcgct
    15481 ataccaagtg aatatatgat ccaaaaaatg atcaaagaaa aactagtact tccattagat
    15541 cattcgaaga tcaaaggatt aaataatatt gatccacgat ttttagactt ggattttgat
    15601 ccagataatc agtattcgat tccatatttt tggggaactt tagggatcgt atataacgat
    15661 aaattctttg atgcaaatca aattaagcat tgggatgatt tgtggaagcc ggaattaaaa
    15721 gacagtttga tgctgattga cggtgcacga gaagttatgg ggctttcttt gaatagttta
    15781 ggctattctt tgaatagtaa gaatatggca cagctgacag aagcagcaaa taaattgaat
    15841 catttaacac caaatgtcaa agcaatcgtg gcagatgaga tcaaaatgta tatgatcaat
    15901 gaagaagcct ccgtggcagt gacattttct ggcgaagctg ccgatatgat gtgggaaaat
    15961 gaacatttac attatgtgat cccaccagaa ggatccaatc tttggtttga taatatcgtt
    16021 atgccaaaaa ccgtgaaaaa taaagaaggt gcctatgatt tcatcaactt tatgctagaa
    16081 ccggaaaatg cggcacaaaa tgcagagtat attggttatt ctacaccaaa tgaagaagca
    16141 aaagcgttat tgccaaaaga catttcgtcg gacgaacaat tctatccatc tgatgacacg
    16201 atctcccatc ttgaagtcta caaagatcta ggatcgaaat acctaggcat ctataatgac
    16261 ctattcttag aattcaagat gtataggaga taatggcaaa actcagtaag aatggggact
    16321 tatcaacgtt ctaaagagct aaaaatcgtc ctttttctat ctgagttttc caatcttcta
    16381 ccaaaagcgg atgaaacgcc gctttttttg tgttatttta ttttttctac cacgtttttc
    16441 taccagagaa aagtggacaa aaccattgta aaatagggcc cgagacgggc tagtaaatct
    16501 aagattgaaa aagttacaga aggataaagt aattggaaac tatgcaaata tacttaaccc
    16561 ttctgtaatc tattaataaa actaatatat gaatccagtt caatatttgt agctatgaaa
    16621 aaacataaaa atcatattag ataaaaacta aattggtaga taaattattt tgtcagatat
    16681 ctgaggcaaa tattcgacta tttgtgtttc aaagtaaaaa ttggaataca aatatagaat
    16741 agacatattg cagccgatag tttattatgc ttttagacac attaaactgg aggaaaaaat
    16801 gaaaaagagc gctaaagatc gagtttttga tgagctgata cgactaacag ggaatatgtc
    16861 ttctgtcact gccgagaaaa tttcgaagaa tctaggtatc tctcgtcaga atgccagcca
    16921 ttatttgacg agattagtgg aagataaaaa ggtcgagaaa ttaccgggaa agcctgtttt
    16981 gtggaagcct ttagatgaat atgcggttgt agataatacg gagcaaataa acgaagcctt
    17041 tcattctgta gttggtcatg acggaagtct gagagaggtc attcaaaaat gtatagccgc
    17101 tgtcaaatat ccgcctaacg gactcagtgt attaataaat ggagccacgg gtgttggaaa
    17161 aagtttttta gccacaaaaa tttttgaata cgctatccat gagcaaatta ttgaaaaaga
    17221 tgcaccattt gctatcttaa actgtgccga ttatgcggac aatcccgaac tgctttcggc
    17281 aacactgttt ggatacaaga agggggcctt tacgggggct gaaaaggata ccgatggttt
    17341 attggcaacg gccaacaacg gctatctttt tctcgatgag gtccatcgcc tatcgaaaga
    17401 aaatcaagaa aagctctttc tatttattga tactggaaac tatcgtccag tcggtgaaaa
    17461 tgtaaattgg cattctgcta aggttcgttt tattttcgcc acgacggaaa aaggtgaaaa
    17521 ttatttatta gacacctttg atcggcgtat tcaaattagt gttatgttgc caacttttga
    17581 agatcgcccc attcgagaac gattagagct gattcaatta ttttttcaaa atgaagcgga
    17641 tgttttacaa aaagatatta ttgtttcaag agaagccttg tctttaatgt tatctcatcc
    17701 ctttagtggg aatattggta agctgaagaa tatcattaaa atcagttgtg cggatgtgta
    17761 tagtcgaaca caagaagaac cattaacgat tgggaaaaat gagatcttga ttcagttaaa
    17821 tatgctggaa tccgaagtag aaagcttgcc gattgctagt ttattgataa agaaaaatca
    17881 aaagataaaa acggatcgaa tcaaaccgtt tgattatgat tcgattttgg aaaaaattac
    17941 tcagctgata aatgaaggta atttcaatga aaatttttct tcgataaaga atgaagtaca
    18001 gcatttggtg catcacattg ataaggattc ttttttatca atgagtagaa aattgatgat
    18061 tcagatgttt agaaaggtct gggtatccgt tttaggaaaa acgtacggat tgacgacgag
    18121 tggacctgtt gcagaaatta ttagcagatc ctatgtcatt tccccaagct ataagacaga
    18181 cttaaccggg ataaatcgta cattagctgc aaatctacct cggacgactt acttatgtaa
    18241 tcagttcttg gagcatttac caccgctctc agaaaaggac gagaactttc taagactgct
    18301 tattgtcgtg actttatctg attatgtaga tgaatccatc gagctgaagg gcctgttgct
    18361 tgctcacgga gatagtacgg ctagcagcat tcaagcagta gtgaatcaat tatgcggcaa
    18421 ttatgttttt gaagcgttgg atatgccagt agagagtaat gtgtcagaga ttgtcgaatc
    18481 gacaaggaat ttcgtgaaac ggcaagtgaa tacagatagt ctagtgctga tcgtagatat
    18541 gggctcttta aatcaaattt acacacagat caagaacgat ttaaaagggg agttacttct
    18601 tctgaataat ttgacgactt ccattgcact tgatattggc ttgaagatga cgatgaatgc
    18661 gccatttaaa cagattgcgg aggatgcagc agacaagtat tcaatcaatg ttcaatactt
    18721 tgaaggcttt tctcaaagta gcaacattat catttcctgt atgtcgggtt tggggatttc
    18781 ggacaaattg aaagatgttt ttcgtcatca tttatcggat gaatccatcg aagttttcac
    18841 gaaggactac agagaactac gtgaattaat cgaccaaaat gatgaaactt attttgacaa
    18901 gacaaaattg gtcatcacga cttcggatct tccacgttcc ttttcaattc ctaatattaa
    18961 tgtttatgac atcttagacg gtgatggagc agccaatttg gagcatattt tgagtcctga
    19021 aatgaagccg gcagaattta accgcttgat tcaggagcta gtaaaattct tttcgttgga
    19081 aggaattgcg gaccgtttga actttctgaa cccaacgatc gtgatgagtg aagtggaaac
    19141 agtcatttct aaatatgaaa attactatca tttcacttta aatggccgtg taaaactaaa
    19201 tctctatatg catacggcat tgatgatgga acgtttattc ttggctcgga cagaaaaatc
    19261 tgaagaaccg aattatgatt tgaaaccaga tgaagatgaa ttttattatg tttctagaag
    19321 tatttttcaa tcaatggaga tgaaatataa ttttaaagtc aatgcttatg agctttcgct
    19381 gctctatgaa ttattaggac cgtatattca aaaataaagt gtctaaaaaa gtgtctaatc
    19441 tgtttttttt aggttagaca ctttttttaa tgtgaattaa cgtgattaaa ccaatgtttt
    19501 taaaagttgg cacaggaatt gcttatataa aagtgaacag aaagaaagga attaaccata
    19561 tgaagaaaat tctaatagcg actcacggtc acttagcttc aggctttctt agcagtattc
    19621 aattactgac ggggaaggtt caagagatta cggtgattaa tgcttatgtg gatgagtgtg
    19681 attttgaaca ggagttgaat gtatttgtaa accaggtgaa cgagcaggat cagatttttg
    19741 tttttaccga tttatttggc ggaagtgtca atcagaagat taccaaaacc tttttggaga
    19801 aagagattgc tgtaactatt ttgtctggct ttaatctgcc aattctgctc gaaatagtat
    19861 tggcaaccaa ggaattaaca aaggaggata ttcaggaact ggtaaataaa tgccaacagg
    19921 aattaaagat gaccattctt gatgaggtac atgtagtaaa tgaagaggaa gatttttttt
    19981 aggaggaaga aaaatgatta aagcagtgcg aattgatgaa cgattaattc atggacaagt
    20041 agcgatgact tggacaaaga gtctaaattt aaccgggtta gtagtagcaa gcgatgaggc
    20101 ggctaccaac gatattcaaa agatgacatt gaagatggct gcaccatcga atgtcaaagt
    20161 cattattaaa acagttgatg acgcgattca tttgttaaaa gatccgcggg cgaaggacat
    20221 gcgcttgatg gttttagtcc ctaatgtcaa agatgcggta aaagttgcga aagctttccc
    20281 aacggaaatc gaattaatga acgtggggaa tgctgggaaa atgacaccgc catcggaaga
    20341 taagaaaacc ttatcaaagg aagtgatgtt aacgacgtca gaaattcaag acttaaaaga
    20401 attagttgaa ctttatccag ataccgtttt tcagcctaca ccggcgatgg aaaaacgttc
    20461 agctatctct attttgagtg atttttagaa aaaggaagga gaaaaattat gtatgatgca
    20521 tttgtagtcg ctttggccgt ttttattgga gttgctggac atgaaatgtt cgggatgtcc
    20581 atgctgagtc gtccgattgt tgttgctccg ttagcaggag cgttgatggg ggatttgcag
    20641 acggggttga ttgtcggggc gtcactagaa gccatcttta tgggtgtcgt caatatcgga
    20701 atctctagta cggcggagcc ttctttggct gctgggctgg ctacagcgtt cgcaatcaaa
    20761 atgggaggaa acgtggatgc gattattccc attgtctttc cactagcagt attaggatta
    20821 cagttaatga atatgatttt ttcttttgta tgtggaccga tggctgctaa atttttcaaa
    20881 tttgcaaaat ctggtgatca aaaaggaatc atcaatctgc acttctttat gtggtttgtc
    20941 cactatgcgc tttatgctct tattccattc tttgccgttt tatttggagc agatgttgtc
    21001 aaaagcgtct tggataatat tccagaggtc atcatgaacg gattaacagt cgctggaaat
    21061 ctgctgccgg cagttgggat ggcgatgctg ttacggatgc tttggagtaa aaatattgct
    21121 gtgtggtttt tctttggggc cgttgttatg gcgtatctcg agttaccatt gattgcaatt
    21181 gccgcagttg gaacgattat tgcaattgtt atagcccaaa gagatctaca actaaaaaat
    21241 atatctgttc atgcagttca aagcgatgct gctgtaaatg caacgcttga ccaagaagag
    21301 gaggatttct ttcaatgaaa ttagctgatg gaatttctaa agatgagaaa aaattggttc
    21361 ggaagatgtt ttggcgctcg atgactatgt atgcttcggt gaatccggtg acgatgggcg
    21421 gcggtggttt cgcctattct atgatgccct tcattaatca tttctacaaa agtgaagaag
    21481 atcgagctgc ggcgctggaa cgtcatacac agtatttttc gacgaccatt ccttgcgcgt
    21541 cctttgtcat ggggattgcg gcatcgatgg agaaggaaaa ttctgaaaaa gctggttttg
    21601 acgtggaaag tatcaacgcg atcaaaacga gtttgatggg accattggct ggaattggcg
    21661 attcattgtt ctggggagtt tggcgtgtcg ttaccgcggg actagcgatc aacttagcca
    21721 atgccggaaa tattttggca ccaattatct ttttagttat gttcaatata cctaattact
    21781 tgatgcgata ctatggcggc gttttaggct attcattagg ctctaaatat attgaaaagc
    21841 tgtatgcgaa cgggttaatt gaaattctga caaaagctgc tagtatcttg ggtctgatca
    21901 tggtaggtgc aatgacgatc agtatggtca aattcaatac cgttttgagc ttttcaatga
    21961 agggcgaaga actaatgaat gtccaagaaa tcctcgatag tatttttaaa ggaattgtac
    22021 cgttattggt aacattgagc tgtttcaaat tactagataa aaaagtcggc gtcatcaaaa
    22081 ttatttttgg aatggtcgtc ttgggaattt tattgtcatt acttggaatc gcatagtagg
    22141 aagctgcagc tactaggctg cagttttttt agcaaggagg gaaaagatga ctattaatga
    22201 agtaatttat tcacccaaac acccattttt taatgctgag ttaaacgacg gaaatgtgac
    22261 tacttcaaac gaatacagct actatcggaa tattcctgat gtaaagggat tgaccttcga
    22321 tgtaagtaat caaaagacat tagcaaacct tgatgtttgc gggacgattc aaacgttgac
    22381 cttttatcga gaaaatttac taactgagga aaaaccaggt gtttgggtca ataaacagct
    22441 ctctcaaacc aattcgttat ccttaaaggt tgaagtaaac gggattgtct accatttgtc
    22501 agaatcggat catcgtattg aagtcgatgt gattcaagac tgtttgccta gatatattca
    22561 tcattattcg acgtttaagg tcattgtagt atcctttgct cccatactgg ctaataagcg
    22621 tttaagtatg cttgttcaac aggtttacat tgtgaatgaa acacacgaaa gccttcaagt
    22681 ttcagtgaaa gatgtgcctt cgtatcaaga gaagtattcg gatcagcaaa atgtgttgat
    22741 ttctcaaaaa ggaaataagg acacgatcgc acaacaggaa gtggcaagct tcgccattgc
    22801 ttttgtggac ccaaatgctt ttgaagaagt aatgactttt caggaatctg atatcgaaaa
    22861 atggctgaag gaaacattga actattttgc tcagctattt gggcagctgt caatgccaaa
    22921 cgatagagtt gtccatctct atcgtcgtgc actttatcaa agcttttcta gtttcggtat
    22981 gaatcgacag ggacaggtcg tcggcagcaa ttggggcagc tatcctgcta ctaatcgaat
    23041 ttggaataag gatatgtatt acgcatcatt gccattcacc atgtttgaac cggagttatg
    23101 tcaaaaaacg gttctatggt ttgatcaata tggcgttaag tttcctggtt caaaatttac
    23161 aggaggtatc aatcattctc tgagtaattc gttatccagt gcgttactgg ctagtcttta
    23221 ttttgaacat actggggata caaaattctt tgagcggtgt ccgcaggttc tactgaatgc
    23281 ttcaagaatt attgaggaca tattagctca acgtcggtca ggggaaccaa tgctttttcc
    23341 atctgtttgg ttatcagacg cctttgcact tggaaagtat cataccggca gcaatctttg
    23401 tctttggaag gcctgtattg gacttgcaga aatttttgaa gccctagaac aactgagtct
    23461 tagcaagcga tacaaaaaca ttgcctgtaa actaaaggaa tcaatttgta aacaaatgac
    23521 tatcgatggt ccttttggtg agcaattttt ggagggaatc ggtgatgagg agaaaacaac
    23581 ctattcagtg aagcactatc aaaaaccgat tcttgagcaa gggttaatct ttttaagtga
    23641 tgtgattgtg gatggaaaaa ttaatttatt gatgcatgat ggagaagaat cagacactac
    23701 gttgatgcct ttttatcaat ttttagataa taaagatcat ttatatcaga acaccatggc
    23761 cttttctgct agttctttca atccaaccta tagcgaggaa atcaaaggca tcacttgggg
    23821 attagaatcc ggcgccactt ttcctggctt tatcactgtt ttaatgagcg agctgcacaa
    23881 ccctcaagct ttcgtaaccc gattagaaga actaatttgt ttggcagatt tagacggttc
    23941 gtggtggtgg tggccgtatc gcttagaggc tcaacaagga gaagtcgtgc gagactttgg
    24001 ctgcggcaaa tgcggctggg catcgggtct ttttgtcagc ctaatgatca gtcaatattt
    24061 cggattgaaa ttcaaaaaag gagtattgca aattgatcct gttgataatt taacgttttc
    24121 ttggaagaat ttgaagttcg gtcaagcctt catttcgatt gaatgtacgc aatccgagtt
    24181 gagtatttca aatttgtcag aaaagccatt gaaaataagt gatacgaaaa aaattcttca
    24241 cgtagaaaag ggaaaaacga ttcacattca aaggagaaaa agatgagtat actaaaaaat
    24301 attacccaat ttaaaaaaat ccagagtcga gcaatcactc ccgaaaatcc aacaggcgag
    24361 aaaggtaaag ctgcgatgtt gccaagcgag ctaggaccaa gccgcaaagg tcgtggcgca
    24421 attccgctga cttctggtga agaaactgtg attgcggata ttactggaac gggaataatt
    24481 cgtcatatgt ggatgacgat tcgtgatcga acagaatttg gcagttttgt tttacgtgat
    24541 ttaatcttaa gaatttattg ggatgggtcg gatagccctg ctgttgaaag tcctttaggg
    24601 gatttctttt gtaatgggtt tggagagcgt tgcgaggtga actcgttgcc gatagtggtt
    24661 aatcctacag ggggctttaa ttcctatttc gaaatgcctt tccaaacatc cgctaaaatt
    24721 acgatcgaga atttacatcc gaaggatatg tcctcatttt tttatacgat aaattacgct
    24781 ttggtggacg aattggaaga aaatagccta tattttcacg caaattggca tcgggaacgc
    24841 attaccaaat tacaggagga ttataagtta attgatcgat taaagggtca aggctattac
    24901 gtgggtactt accttgcgct tacctgccta gaacgttatt ggtggggcga aggcgagttt
    24961 aaattctaca ttgatgggga tagtgagtat ccgaccgtaa cctcaacagg ttcagaagat
    25021 tattttggcg gggcgtgggc ctttcatgag tacgatgagt tcggacgtcc acatgcgaaa
    25081 aactattcaa cagccttttt agggtatcct taccaatcaa atagagatgc cacaagagat
    25141 cgttttgaaa cgggaaaatt gaatgccgtt catgcctttg gtgacgacgc aatgccacga
    25201 catggtcttt atcgttggca tcttcaagac cccatctgtt ttaccgaaga tttatcggtc
    25261 actttacaac aaatcggcaa cgatgatgtt cgcttatttg agcggcaaga cgatgttgct
    25321 agtgtcgctt actggtattc aacagaagct tcaggaaata ctaaacgtca tttcactgat
    25381 cgagaacgct tgccgcgtta atgaagtgtt tttcacatat tcgaagggag gaacctatga
    25441 tgatatatgg ggcaattgaa gctggaggga ctaaatttgt ctgtgcagtc ggtactgagg
    25501 aattaacgat tttggaaaga gtcagttttc ccacaacaac tccagttgaa acaatgaagc
    25561 aggtcattga tttttttaaa ccttttaagg aacaattggc aggcatcggg gtcggctgct
    25621 ttggtccaat tgatattcaa tgcaaatcaa cgagtttcgg tcatatcaca tcaacaccaa
    25681 aacttgcttg gcaaaatttc aattttgtag gaacgctaaa gcaatatttc aatattccga
    25741 ttgaatggac aacagatgtc aatgcggctt gctatggtga atatgttgct ggttctggca
    25801 aagggttagc aggtgttgca tacttcactg tgggaacagg tatcggaggt ggtgccttgt
    25861 tcaatgggac tttcgtggaa gggttcagtc atccggaaat ggggcatatg ttgatcaagc
    25921 gacatccaaa ggacaatttt tcaggaaact gtcccttcca ccaagattgt ttagagggga
    25981 tggcagcagg accagcgatt gaaaaacggt tgggtgtaaa aggccagaat ttattggctg
    26041 acgattcgtt ttggcagatt gaagcctttt accttgccca atgtgcatac aatacaacac
    26101 tgatgttttc gccagataga attatttttg gcggtggtgt aatgaaacaa gaacacatga
    26161 agaaaaaagt tcaggataaa tttgttgagc ttataaatgg atatgttgaa ataccaccaa
    26221 ttgatagcta cattattacg cccgaattag gtgataatgc cggaataatc ggcggattag
    26281 cattggccag aaaagcggta agaaataagc aaccataatt aatgaatgtt tcattgatac
    26341 tcatgtcaaa agtatttaac cgagtaatca aatgatcaaa tgaagttgga taaagcgaaa
    26401 atgaattcaa ataaaaaggc tctaagtcaa atcgtgttgt tttcattaaa tcactgaaag
    26461 gaaatgcttc tgcgtttcct tttttctttt tgttgtgcgc tgtatacctt gaggatattc
    26521 actggtggcg tacacttaaa tagtaatata ttgtgttact ttatgtctgt ggtaatagtt
    26581 atagttgctt accaatgtat gttcattttt cgaaatgttg acttcataat ccttggctta
    26641 atgtttgaat ttttttggtg atagattttt tcagccgtat aaaataaatc gtaattctat
    26701 tatagagagt tgtgattata aaaagatagc aagaaaaaaa aagaaagttt ctatacattt
    26761 taaatatttt attcctattt ctattgctaa aaaagtagaa attctatatt tacctttaac
    26821 tctcgcttct cttgcaaatg tagttagcat tttaatcgat aataaactca ggtagttata
    26881 ttaccttgaa atgattgata attttgtcac ttctattttt tttgcaataa attttttatt
    26941 ttagtgaaaa ataagaaact atttctttga aggcgataag ttagaaaaat attattgtag
    27001 tcttttcttt attaggaatc atcactgttg tatcttatta ccttttctgt ttttcttatt
    27061 agagaaaaat aatttgagag gtagatagtt tttattggag gaagtaatta tgtatatttt
    27121 tgaaacaaaa atttttcatt gcaataattg caacaaagaa atttcatcgg gggaagaggt
    27181 ttggacaaaa atggaaattt ccgccaaaag taactgctcc tcaactgaaa tcaattaaag
    27241 aactagaatt tgagaatgca ctggtaattt gtatgacatg tactgatgaa gtatttcgaa
    27301 aacattttta aaggttgaga tgtatataga tttaaccaat catttatctc tctcggaaaa
    27361 ggaatattaa ctaaccagcg ggttatcaaa aataggtagg aaaactgtac ttaatggctt
    27421 atttcgcgct gattatgaga atatcagtct gtttgattaa tttttagggt tcaaaataca
    27481 gagacaaact ccaggtcggg tttcgccaca agcgaatta
//
LOCUS       DAXLPY010000032        27100 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.032, whole genome shotgun sequence.
ACCESSION   DAXLPY010000032 DAXLPY010000000
VERSION     DAXLPY010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.032"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(56..508)
                     /locus_tag="ACF3UF_001503"
     CDS             complement(56..508)
                     /locus_tag="ACF3UF_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3671627.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(973..1341)
                     /locus_tag="ACF3UF_001504"
     CDS             complement(973..1341)
                     /locus_tag="ACF3UF_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFD3671628.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            1491..1973
                     /locus_tag="ACF3UF_001505"
     CDS             1491..1973
                     /locus_tag="ACF3UF_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFD3671629.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            2010..3020
                     /locus_tag="ACF3UF_001506"
     CDS             2010..3020
                     /locus_tag="ACF3UF_001506"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFD3671630.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(3135..3848)
                     /locus_tag="ACF3UF_001507"
     CDS             complement(3135..3848)
                     /locus_tag="ACF3UF_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671631.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(4021..4628)
                     /locus_tag="ACF3UF_001508"
                     /pseudo
     CDS             complement(4021..4628)
                     /locus_tag="ACF3UF_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            5112..5339
                     /locus_tag="ACF3UF_001509"
     CDS             5112..5339
                     /locus_tag="ACF3UF_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFD3671632.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            5355..6521
                     /gene="hemW"
                     /locus_tag="ACF3UF_001510"
     CDS             5355..6521
                     /gene="hemW"
                     /locus_tag="ACF3UF_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFD3671633.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            6755..7798
                     /gene="hrcA"
                     /locus_tag="ACF3UF_001511"
     CDS             6755..7798
                     /gene="hrcA"
                     /locus_tag="ACF3UF_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFD3671634.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            7892..8455
                     /gene="grpE"
                     /locus_tag="ACF3UF_001512"
     CDS             7892..8455
                     /gene="grpE"
                     /locus_tag="ACF3UF_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFD3671635.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            8506..10335
                     /gene="dnaK"
                     /locus_tag="ACF3UF_001513"
     CDS             8506..10335
                     /gene="dnaK"
                     /locus_tag="ACF3UF_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFD3671636.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            10486..11652
                     /gene="dnaJ"
                     /locus_tag="ACF3UF_001514"
     CDS             10486..11652
                     /gene="dnaJ"
                     /locus_tag="ACF3UF_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFD3671637.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(11734..12363)
                     /locus_tag="ACF3UF_001515"
     CDS             complement(11734..12363)
                     /locus_tag="ACF3UF_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3671638.1"
                     /translation="MGQLSDNQQLCQERINPLLELLERVFSYYGQALLTVHRQQIIIL
                     VNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSFLHAKQVCEWIAF
                     HQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLFKKTLACFSKNNG
                     SIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLLVQT"
     gene            12375..12548
                     /locus_tag="ACF3UF_001516"
     CDS             12375..12548
                     /locus_tag="ACF3UF_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671639.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(12593..13330)
                     /locus_tag="ACF3UF_001517"
     CDS             complement(12593..13330)
                     /locus_tag="ACF3UF_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3671640.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(13332..14834)
                     /locus_tag="ACF3UF_001518"
     CDS             complement(13332..14834)
                     /locus_tag="ACF3UF_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFD3671641.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            15093..17087
                     /gene="uvrB"
                     /locus_tag="ACF3UF_001519"
     CDS             15093..17087
                     /gene="uvrB"
                     /locus_tag="ACF3UF_001519"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFD3671642.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            17097..19913
                     /gene="uvrA"
                     /locus_tag="ACF3UF_001520"
     CDS             17097..19913
                     /gene="uvrA"
                     /locus_tag="ACF3UF_001520"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFD3671643.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            20176..21441
                     /locus_tag="ACF3UF_001521"
     CDS             20176..21441
                     /locus_tag="ACF3UF_001521"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFD3671644.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            21445..22176
                     /locus_tag="ACF3UF_001522"
     CDS             21445..22176
                     /locus_tag="ACF3UF_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFD3671645.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            22311..23195
                     /gene="rapZ"
                     /locus_tag="ACF3UF_001523"
     CDS             22311..23195
                     /gene="rapZ"
                     /locus_tag="ACF3UF_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFD3671646.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            23192..24190
                     /gene="yvcK"
                     /locus_tag="ACF3UF_001524"
     CDS             23192..24190
                     /gene="yvcK"
                     /locus_tag="ACF3UF_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFD3671647.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            24224..25159
                     /gene="whiA"
                     /locus_tag="ACF3UF_001525"
     CDS             24224..25159
                     /gene="whiA"
                     /locus_tag="ACF3UF_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFD3671648.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            25702..26352
                     /locus_tag="ACF3UF_001526"
     CDS             25702..26352
                     /locus_tag="ACF3UF_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671649.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            26539..>27100
                     /locus_tag="ACF3UF_001527"
     CDS             26539..>27100
                     /locus_tag="ACF3UF_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HFD3671650.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         8932 a         4570 c         5721 g         7877 t
ORIGIN      
        1 aaaaatagcg ctagaatttc caacatctct ggaatttcta gcgcttttta attgtttaag
       61 atacaaggga aatatctgtc tggatcaata atttttcatt gatccattga ctaaagttta
      121 cgacataatt gaagttacca ccgattagta tctccgcatg attgtcttta taaagatcgt
      181 attgtaaaag acggtctttt ttatttgcgt aaacatcgtt atggtactgg actaattgtt
      241 ctcggaattg attgattgct gtaaaatcac gatattgaag gttgaaacgc atcgtgattg
      301 gtgcatttag catgaatcgc tgcatttctt ttgctgcttc ctctgcttga tctccgtata
      361 ggaactcaaa aagattacgt tcagaaaatt tccattgccc gccaaccttt gttcctttta
      421 gttttccttc atgaagataa tttctgatag aacgtgtagt aacacctaat tgttcggcta
      481 attcatttac tgagtaaaaa tctttcaatg ttcaccctcc tatgtgaatg gttctactga
      541 cttagttgat atttgcttaa tcacgaaatg tagaaagaac gattttaatt aaggtcattg
      601 taaaaatcaa gtcagaaaat tctaactttt atttctctaa agaaattcgt tctctcctaa
      661 agtgatatta tatttaaata tacctgaaaa taatgggcag tattatgaaa gatcactgat
      721 attttctcgt attttttcct tattcaaaag ttttgcagga aaattgctga aaaaataatt
      781 ttactaagta gaaaattcaa agccattcaa tcagtgattt ttttcagcac aagaaagact
      841 ccttataaaa atagcagata ctttgtcaat taagtgttta accagggatg ataaaaagga
      901 taggattgaa caaaacctgt ataaggtgat gaatagtttc ctcgccagta aaaggtttat
      961 tcgtataaag ctttatcgcc aaaatttatc atgacctttt ttatcttcaa tattaaatga
     1021 aatcaattgt tcaatcaatt cccagttgat tacacttttc caaggaactt tgatgacgtt
     1081 atccgtatat acgtagcctg cttcttggat atttttttca agggcacgaa tcgctgcttt
     1141 ttccggtgcg atagaaaaat gatttttagc aaaactaaat gcaataataa aggtaccatg
     1201 gtcagtaaac ataggttggt tccattttac agttgtgtct agctggggat acgtttctgt
     1261 tatcttagca aaaaggtctt tgatcttttg ttgatgttct ttttctttga tttgattgat
     1321 gatcggctga aatttttcca ttctaaaacg cctccattaa gtggtttgat ttattttacc
     1381 agaaaaacaa tagttatgta taaaaaacga acaaaacaca agtaatgttg taaccgctat
     1441 atttatatga taagatgtct caaataataa aatagaaaag agacataaaa atgattgact
     1501 tggcaaagaa attcttacac gaaaatatat attttgagtt gtatcatcat cgagccattt
     1561 atacaaatga agatgctttg gtaataaaga aagaacaagg atttacaggt acagagacca
     1621 aaagcttatt cttaaaagat aaaaaagata ataactacgt atatctgact tttactacga
     1681 aacaaacgga tttcaaagca ttagggaaga tcgtcggtaa aaggctttct attgtttcat
     1741 cagaacgcat ggaagaacaa acgggacaaa agcagggcgc tgtttctccg tttggttatg
     1801 aaaaacagat tccgattatt attgatgaag agctcttatc aaatgaaaaa cttgtttttg
     1861 caccaggtag accagatcaa acgatggtca tccaaacggt tgacttaaac aaaatcatcc
     1921 agctacttga gatgccgata tttttgatgc cggcaaacga aaaaaacaat taaccaagta
     1981 aaatagtgca tacttggagg tgaagcaaca tgataagtta tccattatta gaaagaaatg
     2041 caacgattgg ggttactgca ccatcctcag gcgtatcaga ggaacaccat tcgttactcg
     2101 aatcagcttt aaagagaatg gaagaaaaat ctttccaagt agttactgga aagacgcttt
     2161 ggacgcaaga taaggaaaaa tcaggtccag caagaaaacg agcagatgaa ttcaatcaaa
     2221 tgatgcaaga tgaaaatatc caaatgatct ttccgacttg gggaggagaa ttattgattg
     2281 agattctcga ttttgtcgat tttgatgctc tacaaccaaa atggatagta ggttattcag
     2341 atattagtac gttgctactt gctgtcacat taaaaacagg gatagccact gcacatggaa
     2401 ctaaccttat tgatttaaga ggagagtact tggatgaaac gacagcaatg tgggaaagtg
     2461 tactgaaaac aagagaagga gaatcgattc tacagcaatc ttctgaaaag tatcaaaaag
     2521 tgtggcccca tgagcattca tcatcttctg ttttccatct cactgaacca acaaattggc
     2581 aatcagtcag cggagatgca gtaaggatga agggacgatt attaggtggt tgtattgata
     2641 cgatcaggca tttaatcggt actccttatg gagatgtcca atcttttaaa agaaagtata
     2701 atgatggaaa gccgatcttg tggtttctag aaaactgtga gctatcgtca gttgatttaa
     2761 gaagatcact tgttcagatg aaactggcag gctggtttga tggcagctcg gggatcatgt
     2821 tcggtagaag tgcggcagag gatttgttag attataaaat gaaggatgta tacgaagatc
     2881 tgtcaaagga attaaaacta ccgatcttgt atgatattga ttgtggtcat gtaccgccac
     2941 aactgacatt gattaatggt gcctatgcag aagtagcggt agaagataga aaagcgactg
     3001 ttttgcaaac gtttatttaa aaaatttttt cctgccttgg agtctatcaa agaccaataa
     3061 atctaaatag aaaagaaagt gaaagaagct gacaaaatgc tgtcagcttc tttttgtata
     3121 acatattaga aagtctaatt atctataact gtcacatcga ttaactgttt cacgtcattg
     3181 ggatttcctg taggaatagc tactacagat gcattatcaa tgatttcttg agttgtttct
     3241 ctaatgaacg ctggataaga tgtttgatct gcaggcattt gccaatgtga aggaactgga
     3301 taactagtga ttgtcccgtc atggttactt gaatacacta aaactccctg gtaactgtat
     3361 ttcccagtga gcataaccac atctttcgga tagactgcac tccctgcatc ataaggggcg
     3421 ataggtgttc ctgcaggata atgaataaca tgtaattcga aatcacccga tgtatctcta
     3481 aaagtattac ctctaatagc tagccaaaca cgtgcgtact caatttgtag atcagaatat
     3541 cctgctaacg gatctattga ctgagaagac tgtgaggagg ttgtgtctat tgttgaagaa
     3601 gaaatatttg tctcaactgt actactagat gtagaagaag tattgggctc tgagacttta
     3661 ctgcttgttg aagatgtatt cgtttcagta gaagctgatt tctgagtact tgatttttca
     3721 gctgaactgg tttgtctgat tgaacttttg tctgtggtcg cagatggatc actattttct
     3781 ttactaggag acgtacatcc tacaaggaat aaagagacca acaataaaat aaaacctaac
     3841 tttttcatat aaaatacctc attatttttt taataccagt atagcataat cctgaatttt
     3901 tgaatccgta aaaccttgtc tatgaatata aatagagtgt atcttctttg ataaatgtca
     3961 gaaaaagtgt gacaaataat catcagtaaa attacttgtc acactattga taaggagtat
     4021 ttaattgaag agaatgatta ggagaaagga tctccgtact ttttatagta atcatagaat
     4081 ccaagtttgt atagacgaat cgttttttct cttatttctt ctgtttcaaa atggactgct
     4141 tgaagaatca agtctgtgaa ttctatagga gctgttccat tcgcagtaat caaattacga
     4201 tctttcacag cttgttgttc tataaaatct tctttattct gataattttc cgattctaac
     4261 caaggaaatt gcgcatttcc ggtgtgtttg taaccttgca ataatccgct ctgagctaaa
     4321 taatcaactg ccccacaaat agcagctact ggtacgtctg tttttaacaa tttatcgatt
     4381 atttgatata aatgatgatt ttttatgtcc catgaattgc caccgatcat aataaaaagg
     4441 tcaacttttt caggtatttg ttcgattaag taatcgattt ttgtttttaa tcctccaatg
     4501 gaagtgacct ctgattggat agaagcagtt ttgttttgcc atttctcatt ttggtttagt
     4561 gtgctagtaa tataagcacc ttcccaatcg gcatattcct ctaatagaaa cgtaatcgca
     4621 gttttcattt tcaagctctc ctttactatc tataacaagg acaacagttt taacctacag
     4681 acattcatta aaattgggta gcgacagcga aaacaacaat tcttaagttt tagacagagt
     4741 atacagatag tcaacttaat taaatacgaa ctaaataaaa atgacaggta atcatttttg
     4801 tttaccagca ttataacatt ttgcatacat ggatgacaaa agaaccaatt cccacttgct
     4861 tgagtacaat attaaaagaa actggaaggc aaaaagtaat tatagaaacg aaaaataaat
     4921 catatcgggc actcagacat gaaaacaacc ctagagatat ataactaggt aaccagttta
     4981 atgaaagaaa aaatcatcca agaagtcgat tcttggattt tttagtggat ttgttcgcca
     5041 aatacgttta gtatgcgtat atgagaggtt gtaagcaaag cgttgtggtc tgagcactta
     5101 aggaggaatc tgtgaaaata gcttttcata tttttgcaga ttttgactta atgccgaagg
     5161 tcagctttgc gattaccgtt tatcgagagg ctgtaaaagc accgtgtagc tccgatgaca
     5221 ataagcaagc atttttagag ctaggtttcc ttgattctaa atatgcggct tatttcaatg
     5281 agttggtgct tgaacgcgat tttaagaagg tcgaaaacag gcacgacttt tcgacgtaag
     5341 gagaaagaat ttcaatgata gaaacaataa atcccgcaga aaacaaggtt tctgcgtaca
     5401 ttcatatccc attttgcgag catatctgct attactgtga ttttaataaa gtttttttag
     5461 aagggcagcc agtagatgag tatgtggaaa tgctgctgaa tgaaatgaaa ataatgctag
     5521 aaagtcatcc gacagcgaat ttagaaacac tttacgtagg gggcgggaca ccaacttctt
     5581 tatctgctaa acaacttgat cgactgttat caggtgctag agagatcctg ccttttcaaa
     5641 atggtaatga gtttactgta gaagcgaatc caggtgattt gacccgtgaa aaacttcaag
     5701 taatgaaaaa ctatggcgtc aatcgtttat ccatgggagt gcagacattt gataatcgct
     5761 tattgaaaaa aattggacgt aaacacaccg cagaagatgt gtatcaaact atgcaatttt
     5821 tagaagcaga aaattttacc aatgtaagca tcgatttgat ttatgcatta ccgggacaaa
     5881 cactagaagg atatctggat actttggaaa aagctttggc tttggatctg cctcactatt
     5941 ctttgtactc attgatcctc gaaaacaaaa caatgttcat gaactgggta cgacaaggaa
     6001 gactcgaact gcctgatcag gaaacggaaa ccagaatgtt tgaagagacg attgaagcaa
     6061 tggaaaagca tggacgtcac caatatgaaa taagtaactt tgggctctcc ggacatgaat
     6121 ctcaacataa cctcatgtac tggaacaatg accactattt tgggtttgga gctggtgcta
     6181 gcggttatct tggagatatt cgttaccgca acaaaggacc aatccaacac tatttacgcc
     6241 cattacgagc aaatgaacgc ccggtattgg aagaagaaaa attgacacga aaaaatcaaa
     6301 tagaagaaga aatgttctta ggactaagaa aaaaaacagg gattactaaa aaacatttct
     6361 atgatcgcta tcaaaaaaca attgaatcgg tgtacggtga tgtgctaagg gaattagagc
     6421 aagaagggtt acttgttaat gaagaagacc gtgtttattt gacaccaaga gggacctttt
     6481 tggggaacaa tgtgtttgag cgctttttgt ttgaaaaata gtttaaagaa tatttgtttt
     6541 ttatctgaat ttaaataaaa aaagttcaaa aatacaataa aggactattg aaacgttgat
     6601 ataactggat ttacatcaat tatttagaat tagcactctt gtgtttagag tgctaaaaaa
     6661 tggagtcttt ctcttgacag gagaagggct tcttgctata tttataagtg gattagcact
     6721 tagaatatat gagtgctaat gagaggtgag gaagatgtta acaaagcgac aaaacgacat
     6781 tttacgtctg atcatccaac actatacgag tagtggcgtg cccgttggtt ccaaaacatt
     6841 gatgtctgag ggagtcaagg ccagctcagc aacgattcgc aatgatatga aagcattaga
     6901 agatgaagga ttgctgttga agactcactc ttcttctggg cggattccat ctgctttagg
     6961 ctatcgttat tacgtggatc atttgttaaa acctgctcgc gtagcagaag atgatttgct
     7021 gctgattcgt cagtctctag gcagagaatt tcatgaaatc aatgagatta ttaagcaatc
     7081 tgctgagata ttatctgagc tgacaagcta tacgactttt tcattgggac ctgaaataaa
     7141 agaccgccga ctgactggct ttcgtatcgt acccttgaat aatcgacaga ttattgctat
     7201 cgtcgtaaca gatatgggga atgtagaaag ccaagtgttc actcttcccg aatatatggg
     7261 aagtcaggaa ctagaaaaaa tggtacagat tgtaaacgac cgtctagtcg gagatcctct
     7321 gatgacggtg taccataaac ttcgtacgga gattccgatg attcttcata aatatttcca
     7381 aacgacagaa gggatgtctc agttatttga caccgttctt ggtcatgttt ttgaagataa
     7441 ggtttatgtc agtggacaaa tgaatctctt ggattatgag ccccgtcaag atcttgatca
     7501 gttcaaatcg atgttttctt ttatgaaaga ctcagacgga cttacacaaa tgatcactcc
     7561 gatggatagc aatattcata tcaagattgg tgctgaatta ggcaatgatt tattgcagaa
     7621 tatgagtatg attcaagcaa gttacgagat agatggtcat ggaagaggta caatagcctt
     7681 gttagggcct actagtatgc cttattctcg gatgttcggt ctagtcgatg tttatcgaag
     7741 agaactagca gctaaacttg ctgattacta ccgttcgctt gacttgtcaa actcgtaatg
     7801 tgaataacga agctatttgc agctgatcgt tctctctttc ttagtaagag caatcaaaca
     7861 gctgactgaa taatgaaagg aagactgtat cgtgaaagaa aatcaagaag aactagataa
     7921 agaaatgaca gatgctcagc cagaaccgga aatcgatgtc gaagctgcag aagattcggg
     7981 tatttcagaa gctgaagcgg aagaattcga aacagcgaaa ttaaaagctg agttagaaga
     8041 aatggaagat aaatacttgc gggctcgtgc tgaaatcgca aatatggcaa atcgaggaaa
     8101 aaatgagcgt gagcaattac aaaaataccg ttcacaagat ttagccaaaa aattacttcc
     8161 atcaattgac aacctggaac gtgcattagc cacagaagtg tcagatgatc aaggggcagg
     8221 tttgaaaaaa ggcgtggaaa tggtcttgga aagtttgcgt aacgcactgg aagaagaagg
     8281 aattgaaaaa atccctgcta aaggagaagc ctttgatcct aatcttcatc aagcagtaca
     8341 aactgttcca gcgactgaag atacaccagc cgatacgatt gtagaagtac tacaagaagg
     8401 ctacaaatta catgatcgcg tgttaagacc aaccatggtc attgttgcac aataattgtg
     8461 cggatataaa acttacactt tcaattaaag aaggagacgt taattatgag taaaattatc
     8521 ggtattgact taggtacgac taactctgca gtagcagtat tggaaggaaa cgaagcaaaa
     8581 atcatcgcta acccagaagg aaaccgtaca acaccttctg ttgtatcatt caaaaatgga
     8641 gaaatccaag taggggaagt tgcaaaacgt caagctgtga caaacccaaa tacgatttca
     8701 tcaatcaaac gccatatcgg tgaagcaggt tacaaagtag atgtagaagg taaatcatat
     8761 acaccacaag aaatctcagc aatgatcctt caatatatca aaggattcgc agaagactat
     8821 ttaggtgaaa aagtcgaaaa agcagttatc actgtgccag cttactttaa tgatgcacaa
     8881 cgtcaagcaa caaaagatgc tggtaagatc gctggtctag aagtagaacg tatcgtcaat
     8941 gaaccaactg cagctgctct tgcctatggt ttagataaaa cagatcgcga cgaaaaaatc
     9001 ttagtattcg accttggtgg cggtactttt gacgtatcta tccttgaact aggagacggt
     9061 gtctttgatg tattgtcaac agctggcgac aaccatctag gtggggacga ctttgataac
     9121 aaaatcatcg actacatggt agcagaattc aaaaaagaaa acagcattga cttgtctcaa
     9181 gacaaaatgg ctttacaacg cttgaaagac gctgctgaaa aagcgaaaaa agatttatct
     9241 ggcgtatcaa gcacacaaat cagcttgcca tttatcacag caggagaatc tggaccattg
     9301 catttggaaa tgacattgac acgtgcaaaa tttgatgaat taacagctga cttagtagaa
     9361 cgtacaaaag taccagtacg tcaagcgcta aaagatgcag gtttatcaca atcagaaatc
     9421 gacgaagtta ttttagtcgg tggatctact cgtatccctg cagttgtaga agcagtacgt
     9481 aaagaaacag gaaaagaacc aaacaaatca gttaaccctg atgaagtagt tgctatgggt
     9541 gctgctatcc aaggtggcgt gatcactggt gatgtgaaag atgttgtttt acttgacgtt
     9601 acaccattgt cattaggtat cgaaacaatg ggtggagtgt tcactaaatt gattgaccgc
     9661 aatacaacga ttccaacaag taaatcacaa gtattctcaa ctgcggcaga taatcaacca
     9721 gcagtagaca tccatgtatt acaaggtgaa cgcccaatgg ctgctgacaa caaaactcta
     9781 ggaagattcc aattgacaga tattccagca gctcctcgtg gtattccaca aatcgaagta
     9841 acattcgata ttgataaaaa cgggattgta aatgtatctg cgaaagatct aggtacacaa
     9901 aaagaacaaa aaatcacgat caaatcttct tcaggtctaa cagacgaaga aatcgaacgt
     9961 atggtaaaag atgcagaagc aaatgcagaa gcagataaag ctcgtaaaga ggaagttgac
    10021 ctacgtaatg atgtagatgc attgctattc tctgtggaca aaacattgaa agaattagaa
    10081 ggcaaagtgg acgaagaaga agtgaaaaaa gcagaaacag ctcgcgatga attgaaagcc
    10141 gctgttgaag caaacaacat cgaagaaatg aaaactaaac gcgatgcatt gaacgaaatc
    10201 gttcaaaact tgactgttaa actatacgaa caagcggcac aacaacaagc tcaagaaaac
    10261 ccagaagcag ctcaaggcgg agcagatgat gtcgttgatg ctgattttga agaagtcgat
    10321 ggcgacgata aataatcagt tcactgaatt tcgagagaag gccaaagttg ctactttggc
    10381 tttttctttt gaaaaatagt ttgaagtatc ggtttttgtt tcaaacaaaa tatgatatga
    10441 taacaagcga cgtgaaaatg atgagaacca ataggaggaa agcctatggc aacaaaacgt
    10501 gattattatg aagtcttagg gctctcaaaa ggagcatcag aagatgaaat aaagaaagct
    10561 tatcgtaagc tttcgaaaaa ataccatcct gacatcaata aagaacctga tgcggaagaa
    10621 aaattcaaag aagtatcaga agcatatgag attttaagtg acccgcaaaa acgcgctgca
    10681 tatgaccaat acgggcatgc aggcacagat ccaaattacg gtgctggtgg agctggtggc
    10741 ggatttggtg gattcggcgg cttctctggt ggcggcttcg gtggttttga agatatcttc
    10801 gactctttct ttggaggagg cggtcggtca gtcgatccaa atgcgcctcg tcaaggtgct
    10861 gatttgcaat atacggtcga cttgtctttt gaagaagcga tttttggtgt agaaaaagaa
    10921 atcaagtata atcgggaaga aatctgtcat acttgtggtg ggaacggtgc aaaaccaggc
    10981 acacaaccaa ctacttgtca taaatgtcat ggtgcaggta cgattaatgt agaacgccaa
    11041 acaccacttg gacgagtgat gagccgtcaa acttgtgatg tttgtcatgg gacagggaaa
    11101 gaaatcaaag aaccttgtcc aacctgtcat ggctcaggac atgagaagaa agcacattca
    11161 gttaaagtga atgtaccagc tggtgtagaa gaaggacaac aaatgcgttt agctggtcaa
    11221 ggagaagctg gagaaaacgg cggaccattt ggtgatttgt atgtggtctt ccgtgtagaa
    11281 gaaagtgata tctttgatcg tgaaggttct gaaatttact atgaattgcc tttaagtttt
    11341 gtacaagcag ctttggggga tgaagtccaa gtaccaactg tccatggaga tgtgaaattg
    11401 aagatccctg ctggaacaca gacaggtacg aacttccgtt tacgtggaaa aggcgctccg
    11461 aagttacgtg gtggtgcaac aggcgaccaa catgtcaaag taaaactgat cacaccgaaa
    11521 aatctaaatg aacaacaaag agaagcatta cgtgcattcg ctgaagctgg cggcatcaaa
    11581 gttgaagaac agcaagaaga cggtttcttc gataagttta aagatgcttt tggcgggaaa
    11641 aagcggaagt agtttttcta gtaaaaacgc taagtcatta ataattaaaa accagacgaa
    11701 caatcatatg ttcgcctggt ttttttgtag ttgtcatgtt tgtaccaaca aaaaagccag
    11761 ctttagaata tgataatcgt catagtttct aggggtataa ccagtgagag aatggaactt
    11821 gttcaatcga tattgcaagg tgtttttatg aataaataat tcttctgagc aatttttgat
    11881 gcttccgtta tttttactga agcatgccaa agtcttcttg aacaaatgta cttcttcttc
    11941 tgtcaggctt ttcaaaatac gttttacata taatgttcgt tgatctgacg ggattgctgg
    12001 taaaacgatc ccgaggtcta aatcttcaaa aaagcggatc tcgttcacag attgatggaa
    12061 agctatccat tcgcaaactt gtttggcatg aaggaaagat tgcggtgtct cttgctctgt
    12121 ataacaaagc gacccaattc caaagtttag ctgtaactga tacattttat taaactttgt
    12181 ctggatttta tcaagcaatg atagcaatga ggctctggaa atccgattga ctaggataat
    12241 gatttgttgt ctatgtacag tgagcaaagc ctgtccgtaa taagagaaga ccctttcgag
    12301 caactccaat aaaggattga tccgttcttg acacaattgc tgattgtcag aaagttgtcc
    12361 cacaactaca taatatggag aagaaaaatc aagctcaatt aagtgagggt ggtatcgact
    12421 atgtacttga tatcatcaat gaaccgatgg tactttctta tgcgatggaa caggtagagc
    12481 gattgcttgt ttgtgcagga aaacaagcga tgcggctgat acgattaggt gagaaaataa
    12541 gaagataaaa atacacggtc ccttcatggc gaccgtgcat ttttggtttt tattaaatat
    12601 ttaatacttt attcaagaaa tcttttgtcc gttcattttg cggattttca aagatttgtt
    12661 gaggcgttcc atcttctaaa aagtttccgt cgtcaatgaa catgacgcga ttggccactt
    12721 ctttagcgaa ccccatttcg tgcgtaacga taaccatcgt cataccttgt tctgctaact
    12781 ttttcatgac gttcaagaca tcaccgacca tttcaggatc gagtgcagaa gtaggctcat
    12841 caaaaagcat gatgtcaggg ttcatcgcta gagcacgagc aatagccaca cgctgttttt
    12901 gtccaccaga aagcatttca ggatacatat cttttttatc ttctagacca actgtctgca
    12961 gtaatttgat tgcttttttc tctgcttctt ctctagattc tttcttcagg tccatcggtg
    13021 ctaaaatgat gttttccaaa atagaaagat gagggaatag gttaaagtgt tggaatacca
    13081 ttccgatatg ttgtctcacc aagttgatat ctgtgctttt atccatcaag tgggcgccgt
    13141 caataataat ttcaccgtca gaaggttctt ctaaacgatt caagcaacgc aagaatgtac
    13201 tttttcctga acctgaaggg ccaatgatac agacgacatc tccttcgttg atggatacat
    13261 tgatgtcgtt taatactgtg ttatcgccgt attttttgac taaatgctca actaagattt
    13321 tttctgccat cttacttcac cttcttttct aaaacttttg ctaattttgt caatgctgtg
    13381 atcaaaatca agtacatgat cgcaatgatc aagtaaacat acgtactttg tgttgtacgt
    13441 gcaacaatga tcttaccagt ttgcagcaat tcgactacac cgattgcgga aatgatcgtt
    13501 gtgtctttta atgagataac gaactgattg acgaatgatg ggatcatgat gcgtatcgct
    13561 tgcggcaaaa tgattttttg cattgtccga ttataagaaa gacctaaact tctggaagct
    13621 tccatttgtc cgacaggaac ggcgttgatc ccgcctcgaa caatctctgc gatataagca
    13681 cttgcgttaa gagtcaaggt gataacacca gcaaggaagt caggaatcgt aaatccaacg
    13741 ataccaggca acccaaagaa aataaagaac gcaagaacca tcattggaat tcctcggatg
    13801 atatcgacat aaatactagc aattgtgcga agagcgcgta ttggtgctac actgaataat
    13861 ccaaaaatca caccgattac tatagccaaa gcaaaggaga tcaaagttag gagaattgtt
    13921 ctccaaagtc ctttcaacaa tgcttgatag ttgttttgga taagtccaag aaatgttgat
    13981 tcatcagcag tggaagactc actggaagtt tctgaaccat ccgctacata ttctttaata
    14041 atcttatcgt attcgcctgt tctttttaat tctttcaatc cttcattgaa catattaaga
    14101 agctcaggat tttgtccttt tttaacggca aatgcatatt ttccgccaga ttcttttttg
    14161 atcggtgttt ccaattcttg tccttgtttg atcgcataac cgattaccgg ataatcatcc
    14221 atcattgcat cgattgcgcc aacttttaac ccgtcgtaca attgatcagc agcatcaaaa
    14281 tatttgatag aatagccata ttcagattca tggtcgctta aaaattcagc actttcggta
    14341 ccaacttttg ctccgactgt ttttcctttc aaatcttcat aagacttgat cgaagtatct
    14401 ccttttttga cagctaattg gatcccgcta tcaaagtaag aatcagaaaa atcatagctt
    14461 ttctttcgtt catctgttac agtcattccg gcaatcattc cgtctgcttg tcctgattcc
    14521 aaagcttgca aagcagcaga gaaaccacgg tagtccattc ggatgttaaa tccttgcagt
    14581 ttggcgatgt tttccatcaa ttttacatcg atgccttcgt actcgccctt tgcgttttga
    14641 aattcaaatg gagcaaaagc agagtcactg gcaattacgt atacgtcttt tttgggctct
    14701 attttttgca ttgtctcgct tgtgcttgac tctgccgttg tagtgttgtc agcttgtgca
    14761 acatgaccaa acgcaagtgt cacaagtcct gtcattaaga aaacaaatga gtgaaataaa
    14821 tgctttcttt tcataatcaa cctcctaaat ttccaatatt ttattattat aggcgaaaag
    14881 tgctgaatca gacaagactg taagctcgaa aaaatgaaaa aaatgcgagt ttctaacatt
    14941 ttatgttata aaacataaca tgtataataa gataaaaaag tggcgaaagt atgttcggtg
    15001 tggtataatt ttttagtaag gaatgccttt gctttccttt tctttttatt ggtcgtaaaa
    15061 tgaaaaggaa tgaatgaaaa ggaggacgaa gaatgattga gagagatacc tcccgacact
    15121 ttgagcttgt ctcgaaatac caaccggctg gtgatcagcc tgaagcgatt aaccaattag
    15181 tggatggcgt agtcggcggg aaaaaagcac aaatcttatt aggtgcgact ggaacaggga
    15241 aaacatatac gatttccaat cttattgaga aagtgaataa accaacactg attattgccc
    15301 ataacaaaac attggctggt cagctgtacg gggaattcaa ggaatttttc cctaacaatg
    15361 ctgttgaata ttttgtttct tattatgatt attatcagcc tgaagcttat gtgccttcaa
    15421 gcgatacgta tatcgaaaaa gattcaagtg taaatgatga gatcgacaaa ttacgacatt
    15481 cggctactag ttcattatta gaaagaaatg atgtgatcgt cattgcatcc gtttcatgta
    15541 tttttggatt aggctcgcct tttgagtacc aaaaacaagt agtttcgatt cgacagggag
    15601 cagaactaga tcgcaatcag ttgattcgtg acttagtcag tatccaattc gaaagaaatg
    15661 atatagattt tcagcgcggt cgttttcgag tgcgcggtga tgtcgtggag atttttccgg
    15721 cttcaagaga tgaacgtgcc ttacgtgtgg agttttttgg agatgaggtc gaacgtatcc
    15781 gagaagtcaa tgcactgaca ggtgaagttt taggagaaac ggaacacgta gcaatcttcc
    15841 cggcgactca ctttgtgacg aatgatgaac atatggagca tgccgtagcg aatatcaaag
    15901 cggaattaga acagcgttta actgtcttgc gaaatgaaaa caaacttctg gaagctcaac
    15961 gtttagaaca gcgaaccaat tacgatattg aaatgatgtt agaaatgggc tacacgtcgg
    16021 gaattgaaaa ttattctcgg catatggacg gacgtaaaga aggtgaaccg ccttatacgc
    16081 tattggattt ctttcctgaa gattttttga tcgtggcgga cgaatcgcac gtaaccatgc
    16141 ctcaaatcag aggaatgtat aatggtgacc gagcgagaaa acagatgcta gtagattacg
    16201 gtttccgttt gccatctgct ttagacaatc ggccacttcg gttagaagag tttgaaaaac
    16261 atgtcaatca gatcatttat gtctctgcga cgccaggacc atatgaacat gaacaaacag
    16321 ataccgttat ccaacaaatc atccgtccga cagggctgct tgacccagtg atcgaagttc
    16381 gtccaatcat gggacaaatc gatgatctag taggcgaaat aaatgaacga gtcgaaaaag
    16441 accagcgggt gtttgtaacg acattgacga aaaaaatggc agaagacctc acagattatt
    16501 tcaaagaatt agggatcaaa gtcaaatatt tgcatagtga tatcaaaacg ctggaacgaa
    16561 cagaaatcat tcgagatctt cgattaggtg aatttgatgt gttagttgga atcaatttgc
    16621 ttcgtgaagg attagacgta cctgaagttt cccttgttgc tatcttggat gcggataaag
    16681 aaggcttttt acgtagtgaa cgttccttag tccaaacgat tggacgagct gctcggaatg
    16741 aagaaggtaa agtaatcatg tacgcagaca aagtaacaga ttctatgcgt ctagcgatgg
    16801 atgaaacgtc aagacgtcgt acgattcagc agaagtacaa tgaagaacat gggatcgttc
    16861 caaaaacgat cattaaagaa atccgagatt tgatttctat tacgaaagaa tcggaagatg
    16921 atacaaaaga agcggtacaa gtctcgtacg aagaaatgac gaaggaagaa aaagacacgt
    16981 tattgatgaa attagaaaaa gaaatgaaag atgcggcaaa agctttggat tttgaaacag
    17041 ccgcgaatgt gcgagatatg attttagaat taaaagcttc aaagtaggag gacaacatgg
    17101 ctaacgataa aattacgatt catggtgcac gtgcccataa cttgaaaaat atagatgtaa
    17161 cgattccacg agataaattc gtggtcgtta caggtttgtc cggttctgga aaaagttccc
    17221 tagcatttga tacgctgtac gctgaagggc agcggagata cgtagagagc ctttctgctt
    17281 atgctcgtca gtttttagga caaatggata agccggacgt agatagcatc gacggattga
    17341 gtccggcgat ttctattgat cagaaaacaa caagtaaaaa tcctcggtcg acagtaggta
    17401 ctgtgacgga aatcaatgac tatttacgct tgttgtttgc acgtgtagga catccgattt
    17461 gtcccaacga tcatatcgag attaccagtc aatcagtaga tcaaatggca gatcaagtaa
    17521 tggctttgcc tgagcgcaca aagatccaag tgttggcacc gatcgtggta aagaaaaaag
    17581 gacaacataa aaaaatattc gaacgaatcc aaaaagaggg atacgtccgc gttcgagtcg
    17641 atggtgagat ctatgattta agtgaagtgc ctgagctgga gaaaaacaaa aaacatgata
    17701 tcgcgatcgt catcgaccgg atcattgtga aagaagggat tcgttctcgc ctatttgatt
    17761 ctttagaggc ggccctgcga ttagcagacg gctatgctct ggttgacgtg atcggtgaag
    17821 aagaaatgtt gtttagcgaa cactatgcct gtccttattg cggatttact gttggcgaac
    17881 tagaaccaag actgttctca ttcaatgcgc cttttggagc ttgtccagac tgtgatggtt
    17941 taggtgtcaa attagaagtc gatcaagatt tagtgattcc agatagaacg aagacactta
    18001 gtcaaggtgc tatcgttcca tggaatccaa tcagctctca gtattatcct caaatgttag
    18061 cgcaggcttg tgaaagtttc ggtatcgatt tagatacacc attcgaagaa ttaccggaag
    18121 agcatcagga gatcatcttg aatgggacag atgatctttt ccatttccat tatgaaaatg
    18181 attttggtgg cgttcgcgat gtagaaacga ctttcgaagg ggtattgaag aatatcgagc
    18241 gtcgttatca tgatacgaac agtgatttca cgcgtgagca aatgcgtctt tatatgacag
    18301 aattaacttg tcagacatgt aaaggttatc gattgaatcc ccaagctcta tctgttcaaa
    18361 tcaatggaac gaatatcggg caaacaaatg agttgtctat tcaaaaagca gtagatttct
    18421 tctcaaactt aacgttatct gaacaagaga aagtaattgc caaaccgatt ttaaaagaag
    18481 taaatgacag actttcattc ttggaaaatg tgggactaga ctatctaact ttgagtcgcg
    18541 cttccggaac attatctggg ggagaagcgc agcgaatcag attggctaca caaattggat
    18601 cgaatctttc tggagttttg tatattttag atgaaccatc gatcggattg catcaacgcg
    18661 acaacgatcg actgattggc tcattaaaga aaatgcgtga tcttggcaac accctcgttg
    18721 tagtcgaaca tgatgaagat acgatgtggg cagcagatta tttgattgac gtcggacctg
    18781 gggccggaga acaaggcgga caaatcgtgg ctgcaggcac tcctgaagaa gtagctaatg
    18841 atgaaaattc tttgacaggg aaatatcttt cagggaaaaa atcaatccct gtaccaaaag
    18901 aacgccgtaa aggtaatggg aaagcaatca agatcactgg tgcttcagaa aacaatctga
    18961 aaaatattag tgttgaattt ccattaggag aatttgtagc agtcacaggt gtgtctggtt
    19021 ctggaaagag tacattggtc aatagtatct taaagaaatc gttagcgcaa aaattaaata
    19081 agaattctgc taagccaggt aaattcaaga caatttccgg ctacgaaagt atcgaaaaga
    19141 tcatcgatat cgatcaaagc ccaatcggcc ggacgccgag aagtaatcca gcgacttata
    19201 caagtgtatt tgatgatatc cgtgggttat ttgctcaaac gaacgaggca aaaatgcggg
    19261 gttataagaa agggcgtttt agtttcaacg taaaaggcgg tcgttgtgaa gcttgtcgcg
    19321 gggatggaat tattaagatc gaaatgcact ttttgcctga tgtctatgtt ccttgtgaag
    19381 tatgtcatgg taaacgatat aattctgaaa cattagaagt gcattacaaa ggaaaaagca
    19441 ttgctgatat tttggaaatg acagtagagg atgctgtaga attcttcaag cacattccaa
    19501 agattcatcg caaactgcaa acgattgttg atgttggctt aggttatgtg acgatggggc
    19561 aaccagcaac gacattgtcc ggtggtgagg cacaacggat gaaacttgcc agtgaattgc
    19621 acaaaatctc taatggaaag aatttctata tactagatga accaacgaca ggacttcata
    19681 gcgatgacat cgcccgcttg ttgcatgtat tacaaagatt agtagatgct ggtaacacag
    19741 ttttagtgat tgaacacaat ctagatgtaa tcaaaacagc agattatatc attgatttag
    19801 gaccagaagg tggagaaggt ggaggaacga tccttgcgac tggaacacca gaagaaatca
    19861 ttaacgtaaa agaaagttat acaggtcact atttgaaaaa aataatggta taaagaggat
    19921 agatagctga gatagttaaa aaaacataaa aaaatgaatt tttgcttgtt ttattaatat
    19981 cagtgttcta gaatcattac atggtagttc tttctacact gattggtata gataaaaact
    20041 tcctataagt tcaatccgtt caaaaaagaa ttgagcaatc ggaggacttt cctttgattg
    20101 cttttttctt tatggtatga tattccttgt gtagttggaa aagaaaaaca agagattatg
    20161 agtaagtgag agataatgat gaacagtatt gaaaatgaag aatttatccc tatattatta
    20221 ggaagcgaca tgaacgttta tggtatggca cgttctttta atgaagcata cggcaaaatc
    20281 tgccaagcat atgcttcgga tcagttagcc cctacccgct acagtaaaat tgtcaatgta
    20341 gaagttattc caggatttga taaagaccct gtatttatcg agacgatgct tcgtttggca
    20401 aaagaaagat attctgataa gagtaaaaaa tatcttttga ttgcttgtgg tgatggatat
    20461 gcagaattga tctcccaaca taaacaagag ctgtcagaat attttatctg tccatatatt
    20521 gattattctt tatttgaaag gctgatcaat aaagtaagct tttatgaagt ttgtgaagaa
    20581 tatgatcttc cgtatcctaa aacattgatc gtcagagaag aaatgttagt aaatggacat
    20641 ttggaacagg aattgccttt tgaattccca gttgctttga aacctgcaaa cagtgtggag
    20701 tatctttctg tccaatttga aggaagaaaa aaagctttta ttttagagac tagagaagag
    20761 ttcgatttaa ttttaggccg gatatacgaa gccggttata aaagtgaaat gattgtacaa
    20821 gattttatcc cgggtgatga tagtaatatg cgtgtgctaa atgcgtatgt agatgaagat
    20881 catcaagttc ggatgatgtg ccttggtcat ccactattag aagatcctac accagcatcg
    20941 attggtaatt acgttgtgat catgccagat tataacgaaa aaatctatca aaccattaag
    21001 gcatttttgg aaaaaatcga atatacaggc tttgccaatt tcgatatgaa gtatgatcct
    21061 agagatggag aatataaatt atttgaaatc aatttgagac aaggtcgtag cagtttcttt
    21121 gtgacattga acggcttgaa tctggctcgt tttgtcacag aagatcgagt gttcaacaaa
    21181 ccctttgttg aaacgaccta tggaacgaat caatcagata aagcaagatt atggatgggt
    21241 gtgcccaaaa aaatcttttt agaatatgct cgggaaaatg aagacaaaaa actagctgag
    21301 caaatgatca aagaaaatcg ttacggtact actgtatttt atgaaaaaga ccgatcaatc
    21361 aagcgctggt tgttgatgaa atatatgttc cataactata ttccaagatt caaaaagtat
    21421 tttcatgtga aagaaggcta gttcatggag aattttttca gtattttagg cggaatgggc
    21481 acgatggcga cagaaagttt tgttcgcttg atcaaccacc gaacgaaagc tacaaaagat
    21541 caagaatatt tgaattatgt cttattcaat catgcaacag ttcctgatcg tacagcttat
    21601 attttagatc gatcagaaga aaatccaatg ccgtttctgc tggatgatat tgagaaacaa
    21661 aatttattgc gaccaaactt cattgtgttg acttgtaaca ccgcacacta cttttttgaa
    21721 gagttacaag cggcaacgga tattcctatc ttgcatatgc caagagaagc agcaaatgaa
    21781 cttgtccgtc agcatacgac agggagagta gcgattctag gaacagaagg aagtatgaaa
    21841 gctggaatct atgaacgcga agtcaaaaat cttggtttcg aaacagtgat tcctgatact
    21901 gcgcttcaag aaaaaatcaa ttacctgatc tatcatgaga tcaaggaatc ggattatttg
    21961 aatcaagagc tctattacga aatcttagag gaagcggtag agcgcctaaa ctgtgaaaaa
    22021 gtcatcctag gttgcacaga attatctttg atgcatgaat ttgctgaaga taatcattac
    22081 ccagtgatcg atgctcaatc tattttagcg gatcgaacga tcgaacgtgc attagctgaa
    22141 agaagcgagg cattggatac agcatcggaa aagtaaaaaa attggatttg gggcaaatat
    22201 cctaaaagat atttggtcca aatctttttg taaaagaaaa agaaaactgg taatgatacg
    22261 cccgggatga tataatttta ttatgcacaa tgtgagaggg gttcgtaaat atgacagata
    22321 atttgcaatt agtcatcata acaggtatga gtggtgcagg gaaaacagta gctatccaaa
    22381 gttttgaaga tatgggctat ttttgtatcg ataatatgcc gcctcgattg attccaaaat
    22441 tctgggaatt gatcaaagaa tcaggtaaag tcacaaaaat ggctttagga gtggatttgc
    22501 gttctcgttc cttctttgaa gaaatccaaa acatgctgat cgaaatcgaa aatacgaact
    22561 tcatcgacac ttctatctta tttttagatg cttcagacga agaactagtg gctcgctaca
    22621 aagaaacaag acgagcacat ccaatggcga tggacggttt gatcactgaa gggatacgta
    22681 aagaacgggc gatactagac gacttgaaag cccaagcttc cgtgatcatt gatacgacaa
    22741 cattgacacc acgacaatta cgtgaaaaaa tcaatgagtc attcaaatca aagggagacc
    22801 aaggatttcg gatcgaattt gtatcatttg gttttaaata cgggttgccg atcgattcgg
    22861 atattgtgat ggatgtgcgt tttttgccca accctcatta tatcccggaa ctaagaccat
    22921 tgaccggaaa agatcagcca gtctatgatt atgtgatgtc ctttgatgaa acgcaatcat
    22981 tctaccataa atttttggat cttctggaaa ctgtattgcc tggatacatt aaagaaggaa
    23041 aaagcagctt gacagttgca atcggctgta caggcggtca acaccgttct gtggcattga
    23101 ctgaacgttt ggcaaatgct ttagggaaaa actataaagt caatgtgaca catcgggaca
    23161 aggataaaag gaaagagacg gtgaaccggt cgtgaaaatg aaaacctacc ggataagaaa
    23221 accaaagatc gtagtggtcg gcggtggcac tggtctgcca gttatcctga aaagtttacg
    23281 aaatcaagga gcagatatca cagcagtagt gactgttgca gatgatggtg gaagcagcgg
    23341 tgcaatcaga gaatcgatcg ctatggctcc tcctggtgac ttgagaaatg tcttagtggc
    23401 gttatcggat atgccacaat tctatgaaga tattttccaa taccgtttca aaaaggaaga
    23461 tcagttttta gccaatcata cgatcggtaa tctgatcatt gccgcagttt ccgagatgcg
    23521 gggaagcact tatgaggcga ttcaattatt agcaaaaatg atgcatgtag atggacatgt
    23581 ttatccttct tcagaaactc ctttgacctt gcatgctgtt tttaaagacg gaacgactgc
    23641 agtaggagaa tctaaaatcg cgatcaaccg taaaaccatt gaccgtgtgt atgtctgcaa
    23701 cacaaatgat aaaagtgaag ccaaagcggc tcgaaaagtc gtttcagcaa ttatggacgc
    23761 cgacatggtc gttttgggac ccggaagttt attcaccagt atccttccaa atttagtgat
    23821 accagaaatc ggcgaagcaa tgctcaagac aactgctgaa accgtctata tctgtaatat
    23881 catgacccaa aaaggggaaa cggaacattt cacagatgcc gatcatatac gtgttttaca
    23941 caagcatttg aatcagcctt ttatcgatac agtattggtc aatacggaaa aagtgcctga
    24001 agattatatg gacccagaga tctatgatga gtatctagta caagtcgcac acgacttcaa
    24061 cggattgaga aatgaaggat gtcgagtgat ttccaccgac tttttagaat tgaaagatgg
    24121 tggtgtcttc cacgatggag acaaagtagt agaagaattg ttccgtttag ttttcggttc
    24181 aaaatattaa gcaatttatt gttggagaaa ggaggagaat aggatgtcat ttgctgcaga
    24241 tgtgaagaaa gaactaactg gtttggaagt tcatcgagaa catgcgaaag cggaattagc
    24301 tgctttgctg cgaatgaacg gctctttagg tattgtgaac cagcagttta ttttgaacgt
    24361 ccaaacagaa aatgctgcaa ttgccagacg tatctattct cttttgaaag atcattatca
    24421 ggtacgaagt gagctactcg ttcgtaaaaa aatgaaatta aaaaagaaca atgtctatat
    24481 cgtccggttg aagcaaggca caaaagatgt gttgatggat cttgatatca tggatggtat
    24541 gatgttcaat ggacacgttt cggacgagat tatgggaaat tcgcaaaaaa tgcgttctta
    24601 cttacgtggt gcttttatgg cctcaggttc agtcaataat ccggaaacga gtcgttatca
    24661 tttggaaata ttttctattt atgaacagca taaccaagac atttgcgata tgttaaatta
    24721 ttacggtcta catgctcgaa cgcttgaacg gcgcaatggc tatatttcgt atttaaaagg
    24781 agcagaaaaa attgctgatt tcttaacatt gattggtgca accaactcaa tgctccgatt
    24841 tgaagatgtt cgaatcgtac gggatatgag aaattcggtc aatcgtctag tcaattgtga
    24901 gacagcaaat ctgaacaaga cgattgatgc ggcttctaaa caaatcgaaa acatcgaatt
    24961 gatcgaagca aaggtcggtc tacatgccct tcctgaaaaa cttcaggaaa tcgcagaact
    25021 tcggcttcaa catccagagg tcagcttgaa agaattaggg gaaatgattc cctcaggtgc
    25081 aatatcaaaa tcgggaatta atcaccgaat tcgcaaaata aatgaatttg cggaaaaact
    25141 gcgtgaagaa gcagtttaat ccaaagaaaa aactgataca tgaagcagga gatgcgaatg
    25201 tatcagtttt ttttaaaagc tatacttgct tttcttccgt caaactataa ttccaacttt
    25261 actggagtaa cataatgttg aaaggcttct attgtttttt aatacaatcg tataaaaagc
    25321 ggggagacaa ctgaatgaag attttagttt tatacataaa cttttgctta atatagaagt
    25381 cctgatatag ataggatcaa gtatttatct ataactggag attaattaaa aactggaagg
    25441 aactgctcga tcaaccttga gaactgtttt tcttacttct ggtcaagatt ctcgtggttg
    25501 gtggataagg atggttgata agttcattgg attagctagt cgaaaacaac caggtgtaat
    25561 taatgtagaa gttttaacaa ggggatggag tgatttattc agtgataatc ataagttcat
    25621 aaatagtaat tgggatgtat ggttggtata cgttatacct gaacttgaac tatcaagatt
    25681 tggtttagaa tttgagaatc gatgtttata aagggagggc aaaaaatgtg cttttttaca
    25741 acttttacta tcattatgat tgcagtactt tttatttttc tagatatagc aaagcgaaat
    25801 acagcatttt tattatatcg ggttttactt cgagcaggtc tcataacatt tatatcgatc
    25861 gttggatttt ttctattcac agttattgta tttatttgga gaactacagc accaccattg
    25921 ccagagatta catatggaga atttccgttt agtcttgaat atgaaataga tgaggaaaga
    25981 attttgattg aagatacggt gattgcagaa tttataggaa gttttagagg gaatgtgaca
    26041 actcaaccta gacgaagttg gagtataaaa cttttaaata atagtggaga gttgaaagca
    26101 tttcattatg aattcttaat aatagaaagt gaagatgtaa caatcacttt aagtagtggc
    26161 tctgctggat attttatgaa tgatggtgga agcaagccac agctcacagt ccgtgatcgt
    26221 attgcaggtt ttatgcattt ttctcactat gacttagaag aagctcgtaa aatacttgca
    26281 gaatatggga tcacattaat caattgggaa tatgcgccac cgataagaaa ttttttcaat
    26341 gattattatt agtcttataa aaaacagaat gtaaaattta tgtgcgcgag tatttagttt
    26401 tccatttttt gtttgataga tatatagcat tgttgaagca tgggatagtg gtgccaattt
    26461 tatcaatgag gttggtcagg cagttaacat aattggtgat gctataaatc catttaattg
    26521 gaattggagg aattaggtgt ggaaacagtg agattatgga tattcatgaa aaattttcgt
    26581 tcggctttga gatatgttat tctggaatca aaatcaggtt attatctgat tgacacagat
    26641 cactatactt tttggggagg ctaccttttt ccgattttta attggataat cccccataag
    26701 gttatgaaaa ttaacttgcc tgcagaagaa ataaatagat taatactcaa caaagattta
    26761 caaaggaaaa gagagaaaga acattctaat gttgcttgga taggtccagc atttgcagta
    26821 gtgacttctt caattgtcgg tcctatgcta gagagtattt atagtgattt ttctattgga
    26881 atacgttatt tatttgttac tttaagtata gctgttcttt tgtgcataaa gggttatgtt
    26941 agcaagaaga ataaagatat tttaacacta atcggtgtaa acaatttatc tagtactaaa
    27001 attatactgt ttcctgaatc tataaaagaa ggatcaaggt tgttgataat ttttataatg
    27061 cttatactgt tttctgtttt atttggggtg atgtttatag
//
LOCUS       DAXLPY010000033        27073 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.033, whole genome shotgun sequence.
ACCESSION   DAXLPY010000033 DAXLPY010000000
VERSION     DAXLPY010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.033"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            2..74
                     /locus_tag="ACF3UF_001528"
     tRNA            2..74
                     /locus_tag="ACF3UF_001528"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="ACF3UF_001529"
     tRNA            78..150
                     /locus_tag="ACF3UF_001529"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="ACF3UF_001530"
     tRNA            155..225
                     /locus_tag="ACF3UF_001530"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="ACF3UF_001531"
     tRNA            238..311
                     /locus_tag="ACF3UF_001531"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="ACF3UF_001532"
     tRNA            323..394
                     /locus_tag="ACF3UF_001532"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /gene="metK"
                     /locus_tag="ACF3UF_001533"
     CDS             660..1853
                     /gene="metK"
                     /locus_tag="ACF3UF_001533"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFD3671651.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="ACF3UF_001534"
     CDS             1983..3455
                     /locus_tag="ACF3UF_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFD3671652.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="ACF3UF_001535"
     CDS             3538..4326
                     /locus_tag="ACF3UF_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3671653.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="ACF3UF_001536"
     CDS             complement(4393..5061)
                     /locus_tag="ACF3UF_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFD3671654.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="ACF3UF_001537"
     CDS             5176..6888
                     /locus_tag="ACF3UF_001537"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671655.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8660
                     /locus_tag="ACF3UF_001538"
     CDS             6891..8660
                     /locus_tag="ACF3UF_001538"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671656.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(8865..9431)
                     /locus_tag="ACF3UF_001539"
     CDS             complement(8865..9431)
                     /locus_tag="ACF3UF_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3671657.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(9431..10387)
                     /locus_tag="ACF3UF_001540"
     CDS             complement(9431..10387)
                     /locus_tag="ACF3UF_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFD3671658.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(10387..11043)
                     /locus_tag="ACF3UF_001541"
     CDS             complement(10387..11043)
                     /locus_tag="ACF3UF_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFD3671659.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            11413..13431
                     /locus_tag="ACF3UF_001542"
     CDS             11413..13431
                     /locus_tag="ACF3UF_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3671660.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    13501..13707
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13858..16272
                     /gene="leuS"
                     /locus_tag="ACF3UF_001543"
     CDS             13858..16272
                     /gene="leuS"
                     /locus_tag="ACF3UF_001543"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFD3671661.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            16620..18173
                     /locus_tag="ACF3UF_001544"
     CDS             16620..18173
                     /locus_tag="ACF3UF_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFD3671662.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(18554..20338)
                     /locus_tag="ACF3UF_001545"
     CDS             complement(18554..20338)
                     /locus_tag="ACF3UF_001545"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671663.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(20353..22074)
                     /locus_tag="ACF3UF_001546"
     CDS             complement(20353..22074)
                     /locus_tag="ACF3UF_001546"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671664.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            22174..22935
                     /locus_tag="ACF3UF_001547"
     CDS             22174..22935
                     /locus_tag="ACF3UF_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3671665.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IRERKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            23902..24170
                     /locus_tag="ACF3UF_001548"
                     /pseudo
     CDS             23902..24170
                     /locus_tag="ACF3UF_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            24842..>27073
                     /locus_tag="ACF3UF_001549"
     CDS             24842..>27073
                     /locus_tag="ACF3UF_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3671666.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         8649 a         4764 c         5654 g         8006 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattatttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaactgt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcacgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaataa agaggttgtg aaaaagctgt cctgcatcaa gtaataagaa
     8701 cagccaatca aaaacagctt ctcatgtttt tgatttggtt ggacttatta ccgcagatat
     8761 aagcttttga gcaccgtgaa taaagaggtt atgaaatcaa cgctctaacc tgagtattag
     8821 agaaaaaaac gcaaaacata tcatttatgt tttgcgtttt ttatttatct ttttttctca
     8881 atacaatata aaataggcgg ctggttcttt tggttgataa accgataatt cagcacatta
     8941 tatgtttcct gtggcagttt ggaacaaaaa gaatcaacca tatccagttc tttttctcca
     9001 ccttcatgac catagtagac gacaaggatc aatcgtccgc gaggcacaag tcgtttcaat
     9061 atttcttcca tagctgtgcg tgtagtctct ggcatagtga tgattgcttt atcacttttt
     9121 gggagatacc ctagattgaa aatccctgct ttgagatttt gttgttcagc tatcacttct
     9181 cctaacgttt cgtggccttg tagaaacaat gagacacgtt cttctaactg acgctgttct
     9241 agcctttcac gagtagcatc gattgcttgt tgctggatat caaaactata gacatgacca
     9301 gtttttccga tgtgttctgc tagaaaaacc gtatcgtggc cattgcccat cgttgcatct
     9361 acgacgtgat cccctggttg caagatttct tgcagtaatg tatggctgaa atgcaaagca
     9421 gtttgcaaca tcagacgctc acctttttcc gtacatcata ttttccttgg aagctatctc
     9481 tgcgaagaag ttcttcatca attgcattca agacttccca ttttttcaag ctccacattg
     9541 gtccaatcaa ggaatcccac ggcgcatccc ctgtcaaacg atggatgatg atctcttttg
     9601 gtatcatttc cagctggtcg caaatgacat tgacatagtc aggacggctc attaattgaa
     9661 ggcgaccttc atgatagtcc cgcaacattc tcgttttgcg catcagatgc atcaaatgga
     9721 gcttgattcc ttggatatct gaatctaaaa tggtgcgtct gacattttct ttcatcattt
     9781 ctaaactttc gcctggtaat ccgttgatca aatgcgtaca aacacggata ttatgtttgc
     9841 gtaatttagc cacgccatct aaataagttt gataatcatg tgctcggttg atcagttttg
     9901 aagtttcttc aaaagttgtt tgcaatccaa gttctaccca taaatacatc cgctcgttca
     9961 gttcagcaag gtaatcaact acttcatctg gcagacaatc cggtcgtgta ccgactgata
    10021 atcctacgac acctggtaaa ttgactactt gctcaaatcg ttctttgatt atttcaactg
    10081 gcgcatgggt gtttgtaaaa ttttggaaat aaacgatgta ttgttggaca tgaggccatt
    10141 tttgatgcat catgtcgatt tctttctgga attggattgg aagagggtct tcaggtgcaa
    10201 cgatcatgtc tcccgaacca gatacactgc aaaaagtaca accgccatgg gcaacagtcc
    10261 catctcgatt cggacagtca aatcctccat cgatcggcac cttgaaaatt ttcccgccaa
    10321 actcatttcg taaagcgtaa ttccaagaat gatatctttt atttccttct gaataaggaa
    10381 aagtcattaa aagtccttct ttctgtaaga gttatctatt tgttttcttt tttctctata
    10441 cactggataa gtcaggcaca gccaagaaag actgagtaag taaccgccga tgatatcagt
    10501 aggaaaatga acgcccagat aaatgcggct tatcccgaca cttactataa taaacatcat
    10561 cagcaattga agcaatgtgc gtaaggttct tttttgaaca aaagctggaa gcagaaatag
    10621 taaagaaccg taaagaatca tactgcctgc tgcatgtcca ctagggaaac tgtaacttgt
    10681 ttcaactact aagtgcgcca atgaaggacg ctctcgcatg aaaaatagtt tgatcaccgg
    10741 gttgatgatt ccagcaatta caataaatcc agaaacgaac caaaatgttt ctgccctttt
    10801 tttcttatac cacatccata aagccgcaca agcaaataaa atgatgacgg taagaggatt
    10861 accgaattta gtcataaaga gttggtagct gttcagatca ggataagaag ctctgacaat
    10921 gcctgtaaac cactgatcga aaccagaaag ccacgacaga tggaacttta cgatccagcc
    10981 caaaatgaaa aacaggacaa gaaagaagct accagccacc tgaaatgatg ttttatattt
    11041 catacaattc ctcctttgaa gcaatgactt attatagcat ttttggtcca gcgaaaaaaa
    11101 cggtaaagag ataaaaccaa tgtatgattc ctctttgaat aaccaatatt cttataaaaa
    11161 aaataactgt aatcggaaag acattttttg gtaatgcaaa tgaaatgtta gggaaataaa
    11221 atcagtgttt ttcgaaatcc ttttaaacaa gaacgtagac gtaggaagaa cttgaaaatg
    11281 aacagaagtt gttcattacg gtaaattaca atatgattac aaaaaacaac aaagctctta
    11341 aataactttt aataaatatt aagagaagtt ataattatta ataatagata aattgaagtt
    11401 ggaggataga agatggaaaa cattgcaaga aaagaacgga gacgtttaga acagaccaaa
    11461 cgttttcgaa aagcaaaacg aggggcagca atcgtgggaa ctgcgatggt aggctgttct
    11521 gtcgctgccc cattagtaca gccggttcct gttcaagcgg atgaaacacc tgttcagttc
    11581 ggcgcaagaa tcaatacagc ggcatttatc acagaaattg ctacttatgc tcaaccaatc
    11641 gctcaagcca acgatctata tgcatcagtg atgatcgcac aagcagttgt agaaagcggt
    11701 tggggcagta gtgcgttatc tcaagcacct tattataatc tttttgggat aaaaggcagc
    11761 tatcaaggac aaaccgtcta catggatacg cttgaatttt taaataatca atgggtaaat
    11821 aaaaaggagc ctttccgaca atatccttct tttgctgaat ctttcaatga caatgcctat
    11881 gtacttagaa atacttcatt tggcaacggt tattactatg ccggtacttg gaagagcaac
    11941 acgaaatcct atacagatgc gacagcttgt ttgacagggc gttatgcgac tgatcctggt
    12001 tacgcaggca aattaaataa tatcatcgca acttacggat tgacccaata tgatacacca
    12061 gctagcggaa acgcaggcgg tggagcgact acaggtggca ataatactgg aagtgcaggt
    12121 agtactggcg gttcaagcaa ttctggtaat acaaactcag gttcagcaac ttcgaccact
    12181 tatactgtcc aatctggtga ttctgtttgg ggaatctcaa ataaattcgg tatcacaatg
    12241 gatcaattga tccaatggaa caacatccaa aacaatttca tttatccagg acaaaaactg
    12301 acaatcaaag gtagccagga aaatggctct tcgacgaata attccggtaa caataccaat
    12361 tcttcaggaa atgctggtac atcaaacgga ggacaaacaa ctggtgcgaa atacactgtt
    12421 caatctggtg attctgtttg gaagatctca aatgatcacg gaattacgat ggctcaattg
    12481 attgaatgga acaatatcaa gaacaatttc gtttatccag gacaacagct aatcgtatca
    12541 aatggcggtt cttctaatgc tggagcaaat actggctcaa atactgggaa tacaagtggc
    12601 tctagttcgt ccagctcaag ttcttctaat acagcttcag gaacgaaata tacagttaaa
    12661 gccggagact ctgtttggag cgtctcaaat aaatacggaa ttacgatggc tcagctaatc
    12721 caatggaaca atatccaaaa taactttatc tacccaggac aacaactgac tgtttcaaac
    12781 agtggatcaa caaacagcac gtcaggtaat acaggttcgt caaccaatac aaataacagc
    12841 agttcagtta atactggcag cagttcgtct caaggcactt ataccgtgaa agcaggtgaa
    12901 tctgtttgga gcgtggcaaa taaaaacggc atcacgatgg atcagttaat cgaatggaat
    12961 aatatcaaaa acaacttcat ttatccagga cagcaattga tcgttaaagg tggaacttcg
    13021 gcaaatacaa atacaggttc aactacttct gcagcgaaac caaatacacc gaatacgtct
    13081 gctacgacaa gtacatcatc cactggtaat acgatgtata ccgtgaaagc gggcgagtca
    13141 gtttggagcg tagcgaacaa acatcatatc acgatggatc agttaatcga atggaataat
    13201 atcaaaaata atttcatcta tccaggacag caagtgattg tgaagaaagg ttcatctcaa
    13261 tcaacaaacc aacaatcagt tactggttcg aaaacctata ctgtgaaatc tggagaatct
    13321 gtttggagtg ttgctgacag tcatggaatt acaatggctc aactaatcga atggaacaat
    13381 attaagaaca actttattta tccaggtcaa acgttgattg tagctaaata aaatagctgt
    13441 tcgaagaaat aacgattgaa ttccacaaaa atatttgtta ctataaggct acttaaatat
    13501 gacaacactt gaaaaggaag tagtaaaaag actgaagttt cagagagcgc atggctggtg
    13561 agaatgtgca cggatgcttt tgaactcgcc tttgagttgc ccttgctgaa tacccgagta
    13621 agcaagcggc ggtgacggcc gttacaacgt tcgaggcctt ttcactaagg taaaattagg
    13681 tggtaccgcg tagattacgt cctataaaaa gagcaatctt tttataggat ttttttattt
    13741 cttttgtgaa gtttgagaaa acaaagcaaa aggaaataaa aataaacaga ttctgccggt
    13801 tttttcgtta tatttataat agaaacaagt gttttcaata gaacaggagg acagcaaatg
    13861 agttacaatc ataaagaaat tgagaaaaaa tggcaaaaat actgggcaaa aacgaatact
    13921 ttcaacaccc atgatgatcc tgaaaagcca aaattttacg cactggatat gtttccctat
    13981 ccatccggtc aagggctaca tgtagggcat cctgaaggtt atacggcaac ggatatcctt
    14041 tcacgtgtga aaagaagtca aggatacaac gtgctgcatc caatggggtg ggatgcattc
    14101 ggtctgcctg ctgaacaata tgcgctagat acaggaaacg atccagctga gtttacccaa
    14161 aaaaatatcg aaacattccg acgccaaatc aattctttag gatttagtta tgactggaat
    14221 cgcgaagtga atacaactga tccggagtat tataaatgga cacaatggat ctttacgaag
    14281 ctttatgaaa aaggtctagc ttatgaagca gaagtagcgg taaactgggt acctgaatta
    14341 ggaacagtta tttcaaatga agaagtgatc gatgggaaaa gtgaacgtgg tggctatgat
    14401 gtagtcagaa aaccaatgcg ccaatggatg ctgaaaatca ctgcttatgc tgatcgctta
    14461 ttggatgatc tagaattagt tgattggcca gaaagcatta aagaaatgca aagaaattgg
    14521 atcggtcgtt cagtaggagc aaatattgaa tttaaagtgg ctggtacgga taaatcctat
    14581 accgtattta cgacacgacc agatactcta ttcggtgcaa cttactcggt tcttgcacct
    14641 gaactagatc ttgttagaga aattacgacc cctgaacaaa aagctgctgt agaagcttat
    14701 atcgaagaga cagctaaaaa atcagatcta aagagaacgg atcttgcaaa agaaaaaaca
    14761 ggagtattta ctggtgctta tgcaatcaat ccagttaatg gcaaggaaat cccaatctgg
    14821 atcgccgatt atgtattatc ttcatacggc acaggagcca tcatggctgt tccagcacat
    14881 gatgaacgtg actttgaatt cgctcaaact ttcggactag aaattcttcc agttatcgaa
    14941 ggtggagatg ttgaaaaagc tgcttacaca gaagatggta cgcacatcaa ctctgaattt
    15001 ctagacggca tgaacaaaca agaagcaatc gataaaatga atgaatggct agaagaaaat
    15061 ggcgtaggga aaaaagaagt cagctatcgc ttacgtgact ggctattctc ccgtcaacgt
    15121 tactggggtg aaccaatccc aatcatccat tgggaggacg gaacagtcac agctgtccca
    15181 gaagaagagc taccattacg gttgcctaag acaaaaaaca tcaagccaag cggtactgga
    15241 gaatctccat tagcaaatat cgaggagtgg gtcaatgtcg ttgatcctgt aacaggtaaa
    15301 aaaggccgtc gcgaaacgaa tacaatgcca caatgggcag gaagctcatg gtattacctg
    15361 cgttatatcg accctcataa caaaaaagaa ctagcagatt atgaaaagtt gaagcgttgg
    15421 ctaccagttg acatctacat tggtggagca gaacatgcgg tacttcattt actatatgca
    15481 cgattctggc ataaattctt atacgatatc ggtgttgttc ctacaaaaga accattccaa
    15541 aaactataca atcaaggaat gatcttaggc gaaaacaacg aaaaaatgtc aaaatctcgt
    15601 ggtaatgtag tcaatcctga tgatgtggtc gaaacttacg gtgcagatac actgcgcatg
    15661 tacgaaatgt tcatggggcc attagatgct tcgattgctt ggagcgaaaa tggcttagaa
    15721 ggaagccgta aattcttgga tcgtgtatgg cgtttgatcg ttgatgagaa caataaaatg
    15781 cgtgaccgta tcactacatt gaatgatggc aagcttgata aagtgtatca tcaaacagtg
    15841 aaaaaagtga cagaagacta tgaaaatctt catttcaata cagcaatctc ccaattgatg
    15901 gtctttatca atgaagccta taaagtggac gctctgcctt atgaatatat cgaaggattt
    15961 gttcaactac tcgcaccgat tgctcctcac atgggtgaag aactatgggc aatccttgga
    16021 aatgatggtg gtatttctta cgcaccatgg ccaacatacg atgaagcagc acttgttgaa
    16081 gacgaagtag aagttgtttt ccaagtaaac ggtaaagttc gtgcgaaaag caatgttccc
    16141 cgagacttag gaaaagatga gctagaaaaa gcagcattag ccaatgaaat agtgcaagaa
    16201 tatattgaag gcaaaacagt cagaaaagtt attgcggtac caaacaagtt agtcaatatc
    16261 gttgctaatt aattggctct ttgtcaataa ggactgatga gttgtgcaaa atcaaatctg
    16321 ggccagaatg aacttcattc tgtctcagat tttttgttat ttcaaattga ttaattgatt
    16381 gatcaaaaag gttttgattt tcatgttctc aaacacgttc aatgtctttt tcttctgaat
    16441 ggtcttgtaa gagatctctg taatcatcaa atttttgtct attaatctta gtattttttg
    16501 atgtataaac tacctgaaat tgagagtaca taccaaattc ataaattttt tattagtggg
    16561 actagtgatt gtatggattt tgacgcataa tgaatgaagt atgagaaaag gagagacaaa
    16621 tggatcaaga actatttatt atcgaagtat tatcagctaa acaaaaaatt atcgagaaag
    16681 cgaaaaaaag agcgaaaaga ataatgttca agcttttaag cttagtattt ttctctggtt
    16741 tgcttttttt cggagctgta tcgttcctat atcgccatat gagtgcagta gtccgttcag
    16801 ctgaagggat gcaaaaatta aataatttgt atcacttttc gtggggagtt ggcggaataa
    16861 caattgttgt gcttattgtt tttcttctac ttatttggct ccgttaccat caattgtcgc
    16921 gtcatttcga tcaatggctt agtcaaagag cacaacagtt tttacataat aaaccaactt
    16981 ctcaagatga tgactatctt tattttgaga agacttcgac gagtcaagct tttcggatac
    17041 aaaaaagtga ttgccagtta ttgctgagat cacttgatga tttacctatc tacttaggcg
    17101 aaagcaaatc aaaattcgga atgaacacat tccatatttt tttactagaa aacgaaccca
    17161 gatgggaaaa aagccagtct tcgcctggtg gatacctgac aactaagatg agtacattag
    17221 tcactggttt tttcctcatt cttttagctg gaacaatcta ttatgggaga tacactcagc
    17281 caaaaatgtc ttctcatata aatgctgctt ctcacatgac aatgaactca actaacgata
    17341 cgcatataca aaagacaaat gaagggttgt tagctgatcc taagcaaaag gtaaatttga
    17401 caacacaaaa gataaatgat ctcaaacttg atacagagac gcactctctc tatatgacaa
    17461 cagatagtgg tgctaattgg gtatttgtgc cgattgattc gcaatggttg cgttttggcg
    17521 aatacaccct gacaacgggg ctgattcctg aaggttattg gatggacaac acatatgata
    17581 tttccgccga tttctcatgg tttatctatt cttctgggga tgatgtacgt ctgctgactt
    17641 caagagataa tggtaaaaca tggcaaacgt ctattatcac ccaatcagtt cagccgatac
    17701 gttatcgaaa agcggtattt tatggcaacg atggtctatt tatctgtaca tcagccagtg
    17761 ggatgtctgc agaaactttg tacatttaca ctactatgga tggcggaatc acttggataa
    17821 aaagtggaag tacaatgatc aatcagccag tacaaaatgt cagcttcgtt acaacttctt
    17881 taggttttgt ttcgacacgt gaaagtttgt tttatacaaa caacggagga cgctcattca
    17941 aagaatcagt tctgtcgatt ccggaaaact atcagacagg ggggatagat ctttttcaat
    18001 caccaaatga agttactcaa ataagcgcga atacgttaga gacaaaattt tatttgttga
    18061 aaaaaggacc aatcgatgca gggaaaatgt ttgcctgcct cttccgttca actgataacg
    18121 gggaaacatg gcaattcgtt cagcaactat cgcaagtaga acaaggagat taaagaagag
    18181 agattgtgag cctgacgttc agcaccgagt cacaagaaac aaattcaaaa aacagcttct
    18241 catatttgtt gaatagtgta actcgtgatt cggagttgac aagagcaaca agaagcgatt
    18301 ttgaagtata gcttctcgta ttttacaaga tcgtgtctta ttgccgatag gttgtctctt
    18361 gaacaccgtt tattcgtaaa aagggattgt gacaagtctt ttgtcactac ttaccgaacg
    18421 aaactgaagg agctatccaa aaagtatcat tagtattatt ctttgtgttt ctagtggcac
    18481 cactagtaca tttaaaaaag ctatcgatca tggactaatc atacatgatc gatagctttt
    18541 tagataatgt ttgttacgct atctgaaatt gactattata aagactggca taaagcgttg
    18601 gtgattggag tagttcagaa tgtgttcctt tttcgacgat atcgccattc ttcattacaa
    18661 ggatcatgtc tgcattttca atcgttgaca aacggtgtgc aatcacaaaa cttgtcctat
    18721 cttttgtcac agcttccatt gcttgctgaa tcaatgcttc tgttcgtgta tctacgctag
    18781 aagttgcttc atctaaaata acgacaggag gattcgctag aatgactcga gcaattgtca
    18841 ataattgttg ctgtccttga gataacgtgc cgttttcgct agaaatgatc gtatcatatc
    18901 cgtctggcag tgttcgaata aagtgatcac attgtgcgat ttcagccgct tcgataattt
    18961 gttctcttgt ggcatccatt ttcccgtagg cgatattatc agctaccgtt ccttcaaaca
    19021 gccaggtatt ttgtaaaacc atcccaaaag aacgacgtag ttctccacgt gaaagcttgg
    19081 taatatcaag accgtcgaat tcgatctttc ctttattcag ttcataaaaa cgcatcagca
    19141 gattgactaa agtcgttttt cctgcaccag ttggaccaac gatcgctacc gtttgttttg
    19201 gctttactga aaaatcgact tgattcatca atattttatc tgatgtgtaa ccaaactgta
    19261 catttttgaa agctattttt cctttcggtt gttctaaaag tcttgcatct ggaaggtctg
    19321 gaatttcatc tgtttcatct aatatctcaa atatcctatc gattgctgcc attgcggatt
    19381 ggatcgagtt gatcacataa gaagcggtag aaattggttc agaaatctga ttgatgtact
    19441 gaagataagc ttgtaagaag ccgatcgtca caccacctga tagaacaagc atagcaccga
    19501 ataccgcact tatgatgaag gcgagttgat taatgaaacg aatggccgga tagatagcaa
    19561 agttcataaa ttgagcacgt ttaaaagcgt tgtattgctt tttatttact tcgtgtatag
    19621 cagcttctgc atgagcttgc tgattgaatg ttttgaccac tagattacca gctaagattt
    19681 cttccattcg attatttaaa acacccagtt catactgatt ctgttcagaa atctgtttgt
    19741 ttttgttcgc aatcttagtt gtaacaattg aactgccaac gatcagcaat aagacgagca
    19801 aagtaagctt gctttcgata taaaacagca tcagaccagc agcagctatt gttacgacag
    19861 aagtaaaaaa ttgattgata cctgtcaata acacttgaga aagttgattg agaccggtag
    19921 ttgtccgact aatgatgtca cctacttgat gattgtcaaa aaacgacatc ggtaatgttt
    19981 tgaatttttt tgtgatttct tttcgcaccc tcaatgtgat cttttcgctt aacgctgcca
    20041 ttgtccgttc ctgaataaat gaagtgatgc tgcttaagac tgaacagccg atcagcaata
    20101 agacagggaa caacaatgct tgtttgatat cactgaaaga aagctgtcca atacctgttt
    20161 ttcttatttc tgataagaga tcatcgatcc cgattcccat gatcaagggc atggctacga
    20221 ctaataggtt cccgaataaa ctgcatagaa acaatccgta aaaatattta tgttcaggtt
    20281 tgatcatttt ccaaaaacgt atcaaagcac gcgtgttcaa cgtttttttc ttttccatcg
    20341 tatcccttct ttctatattc cttgtgattt tgcaaactcc tgataagttt ggcaattaga
    20401 cagtagttct tcatgagtac cttgtccaac gatttttcct tcatctaaaa caatgatgtt
    20461 atctgcttgt tggattgtac tgaggcgttg agcaacaatc acgagagttt tctccgacat
    20521 gtgtttatga agggctgctc ttaatgctgc atctgtttta tagtctaaag cggagaaact
    20581 atcatcgaat acatagatct ctgctggttt gatcaacgct cgagcaatac atatccgctg
    20641 tttctggccc cctgaataat tagaaccgcc ttgagcaaca aagctgtcca atccgtcagg
    20701 aagggtgtcc actagttctt ctaattgagc gatcttgatc gctttagaca actcttctgt
    20761 tgaggcatat tcatttccca tctgcaagtt gcttaaaatt gtcccgctga ataagaaagc
    20821 cttctgaggg acataactga tgtgggagcg gatctgttct tgagtcattt gagtaagagg
    20881 aataccacca agggttactt ttcctatcgt agggtcacta agtctcaaga gaagtttcgc
    20941 caaactactt tttccagatc cggtcccgcc aacgatcgct gttgtttttc ctttaggtat
    21001 tgtgaaatca atatcttcta gaactggatc agagatttca gtatatttaa atgtgacatg
    21061 ttcaaaagca gctgcatttg tctgatcaaa ggttggttca gctactgttt tgatcgtctc
    21121 ttcctcaatt tcgatctctg cttgcagtat ttcttctatc cgtcgtaatg aggcaaacga
    21181 tttagggata atgaccaata ccatagctgc gatcatcaag taagcaagtg tcagcataga
    21241 gtattcgact acagcagtca cgacaccgat ttgtaatgct ccttctgcta caagatttcc
    21301 gccaaaccac aaaatagaag cataaacgat tcccatgagc aaaaaagcaa ttggagtgac
    21361 ccaagcaaat attcggttca ctttgatcat ttgattagca tagtcagcaa agctcttatt
    21421 cgttcgcttt tcttcatatg attgattatc aaaggcacgg atcatattaa tcccagtaaa
    21481 gaattctctc aatgtgatgg tgatccgatc catttttggc tggatactca aagataaagg
    21541 tgcccctcgt ttcatcagtc gataaacaat ccatacataa aaaacaacag agatcaatgt
    21601 aacccatgtt agtaatagag aataacgaaa catcatgaga atggtgaaaa cgcaaataac
    21661 cggtgctggt aagatcattt ggcaaaataa aacaatcatt tgctggacat tatcgacatc
    21721 attcgtcatt cttgtcaaaa gagatccaga actaaaacga ctgatatcct tcattgacag
    21781 ctgttggaat ttacggaaat atttctcccg cgtttggaat ccaaacctag cggaagccaa
    21841 tgctgaaaag taactagagg caactgcagc gattgttcct agaaacgcta caagcagcat
    21901 ttcaactcca atttttttta taactgaggc ttcgccactt gctatacctg tgtcgatcag
    21961 ctttgctact aattttggta cacctaatgt accggcgatt tgtaaacaga tcatcacaaa
    22021 ggtaaggaga gcgagtcctt tgtttttctg taagaatgtt tttaagatag acatattatt
    22081 cctccttttt tcctgatact tttcgattct ataccttcaa gtaacttgaa ggtcaataga
    22141 aaaaagaata aactgaaaaa gaggtgagaa aaaatgaaaa aaatgtatac gattggccaa
    22201 gtatcggaac tatttgattt gccaaaatca acgatccgct attgggatga acaaggatta
    22261 atccgttcaa gtagacaaga agagaatgat tatcgattgt ttgatatcga tgatattttt
    22321 atgctttatg atatcgtttt ttatagaaaa ttagatatac cgatcaaaca gatgaagaat
    22381 ttatatggaa aaacattgac ggagttatat gagacacttg atgaaacaga aagaagaatc
    22441 cataaagaac tggtggtgat gaaacaaaaa caaaaagaga taagggagcg aaaaaaacag
    22501 ttgaaattga tgatcgatac aaacgaggaa gaatttcctg tagaagagat cccttttgac
    22561 tgtatgatct caacggagtt tgaagatatt gtggaaatca aaaaatttct acctaactat
    22621 tcaagctttg ggatgatgag tatgccagct tccagttcac agacgatgta tggatttttt
    22681 atcgacccta gtgaagtaca tttatttact caagacgtga tttgggagaa aaaagatacg
    22741 gctgtttatc gtcgattctt attgaaatcc gagatgaacc atgcggaacg taataatatt
    22801 ttagaaatca gagaaagaat gtatgaaaaa ggatggaaaa caggagaagt gatcggccag
    22861 tatctattga cgaatacgga tgaaaacaat atcagaactg aatattatca tgcatggata
    22921 gaaatgaaaa aataggaaat atgtgtttaa gataactcga aaatgatggt tgttttagtt
    22981 ataaagaaaa attttctggt tcgattacgg gtttaatgtg ggggattatt agtcgtggat
    23041 agatagaatt ttagtttttt agaggaaata tgtctttaaa aatggaatgg ttgcaattct
    23101 tagcgatata tacgatgtaa ttgtcctctt aaaaaagtat ggaaaaataa ttgtattggg
    23161 tgttatgtat aattcatggt gaactgagac taatgagaag aaaaattcat attgttatga
    23221 gtgagattgt atcagatgag aatgataaat taaataggtg cataaaagca ttacacttaa
    23281 aatacattgt tgcttacatt attacaatat gttaataagg caaaaataaa tagatggatt
    23341 gaataaacat attttttaat caaatagtcc ctactgtgac tttcctcagc tatcggtgat
    23401 actaccgata gcattttttt gcttataaaa taattataag tatttagaga tttttcttct
    23461 aacattcttc aaacaagaaa aatcacaaag gttattgtta tttttatata ttctttttaa
    23521 gaatgattat ttttttatag aaattttaaa aaataaaaca cgttattgat ggatagttag
    23581 tttgttattt ggtaatatta tagaagttga ctggtagtga tttatttttc gttgttttat
    23641 aaaaatgtta ttttttggaa aaattcacaa atatgtaacg aatgtttttc tggaatttgc
    23701 tgtgttaaaa agcagtatga ctaatataaa tactattgtc atttatgcaa ttttttatgg
    23761 atagtaattt tagaggggaa tcaatgaagg aagaatagaa gggaaaaata gttgcaaata
    23821 cgccagttag caaaaatagc aatacatctt caagctttaa aattcgagag aatcatcttg
    23881 gtagtggaat caactacaac aaaaggatta aaccaattaa tagatagaat taccaatgga
    23941 aaaatagaaa aggtagttat tctatacaaa agttgtttaa ttcgcttcgg ttatgaactt
    24001 agtgaaaccc tttgcaatat atggtacaga atatagaaat tattgacatt acagaaaatg
    24061 atgaagattt aatacagatt gtcactattt gtagatacct tttacaagga aaccgagcca
    24121 ataaagctaa gaagatgatt aaggagttga tggaagacga tacaagttaa gaaagtaaaa
    24181 ctacgcccaa ataaagagca aaaagagtaa ttggacgtgg aaaatgcaag aaatgaacca
    24241 tcgattcggt ggacagttta ttagtaatga cggtttgaga acatccatga cgagaatgaa
    24301 ggaacatcct aaatgcgttt agttgaacca agtgccaaat aatatggcca aataagcgat
    24361 cagttatcga tgaatcccaa gtattctaaa ctatatattc attttgatgc taagcattga
    24421 tatatttttt tgggattgat gaaggttaac caatacaggg actcactgat gaaattctag
    24481 agtctgacct tggtatcaac gatttagtga ttgtttctaa tggaaaagta taaaagtata
    24541 taagtacatt aacaaaataa ctattagggt tacgctccag cttgtgcaag gcactggcag
    24601 gaggaatcgt gaaatcataa ttatggttaa gccacacgga caactaaaag tcatacaaag
    24661 ctatcgaatc aatcaacaga agacaatcgg caatcattag ctttgtttac agcttacatt
    24721 gcaacgcttg agttgaaccg aaaatacgag ggaggtaacg cagccatttt gagttgggga
    24781 atctttttag aaaattatcg ggtaccttgt tgtttagtca aaattataag ggggagtaat
    24841 agtgaggaac aaatttcata aactgttaag tatgtttcta gttatgctta ttgtgatcaa
    24901 tcaatttggg aacataacgg ttctagctga gtctttagca gaacagccag agcgttcgct
    24961 gacgatcgaa gttgatcaag aggaggctgc tttgggtgag cagttccagt tgcgagtcag
    25021 aggaacacca gacctgctaa atgcattggt cattgataag agtgaggatt tgattgaagg
    25081 ggaagtgaag caactcaatg attacgaacg tctgattact tattcttccc agcattcagg
    25141 taaatacgaa ttgaccgcaa gaagcggtga tattcaatca aatacggtct caatagaaat
    25201 cagtgtacca gaagaaagca caagtgagtc ttttaatgta ccagaagaaa gcacaagtga
    25261 atcttttaat ataccagaag aaagcttaag tgaatctttt aatgaagcca gatcatctga
    25321 gccatctata acgcaggaat ctcagattga aagacaagag gagctcttga attatgacat
    25381 cggcatctct gctgagcgcc ccactttgcc gagcaggcat acacaaacgt taaagggata
    25441 cattcaagga ggcgctggcg atattcttga agaatatggg gagatggtcg tacgagttcc
    25501 tagagcatcg attggcttaa ttgagttcat tagagtggag gtcgctgatg attcaccttt
    25561 aaagccactg gcattttacc aagaaggcac agacgttgtt tttccattta cctttgatta
    25621 tgaaggatta aatgaagccg ctcagtcgta tacattcagt atcacgtttg aagttgcttt
    25681 ctttcaatca ggcggtactg agccaaataa tgactttcaa gtgagtctta cttatgctga
    25741 gcgagcagca aacacggaat tttcaattac gcctattcct tcatcaagac ccattttttc
    25801 gaaattatac tatggctcta gagaaatcga cagccaagga aatcttggga atctgctgat
    25861 tgacgggcaa gacgtgacca acagtaataa atttattttg caggtaaatt atgaaggatc
    25921 acgaaaagac ggtgtagtgg ttaccgatgt actaccgcaa ggaacaactt tggcaccgaa
    25981 tccgactaca tggagttcca ctggaaatag agaacctatt tcaggtgggg ttcggatcgc
    26041 agaagtaacg aatccaggtg aagcaaacgt tagaactcat tatgtttccg aggaatttgt
    26101 ggacaaagta tcttttaata aggaaacgaa tacacttgtt gtggactttg gtaatctagc
    26161 agagggtcaa tcgtatttta ttgaatatgc tcttgaagtg accgatgtcg acttgttcaa
    26221 tgaaggaaga caagaggatg ggttttctcg gaatcgagcg agtatgacct acaataatca
    26281 ggtaatgagc cgagactacc gcttgagaat ccctgaaagt aatcttccgg caatctcttt
    26341 aagaaaaagt gtggacaaaa atgttatcaa tctcaatgaa aatgaactaa cgtatactct
    26401 gcatgtctcg atgttttctg gaacaagcaa tacgcttgtt attgaagatg ttttggaaga
    26461 aggcatggaa tttgtgtcat ttctatcaga tattccctct ttcattgatg ccgaagtcaa
    26521 taatggaata gttcgtttca gtgcgaataa tacgattggt ggtccgacaa gttttaccct
    26581 ctcttttaag gtcaatgtag aggcgtatgc ggtcggcgat caaattttaa actttgcaac
    26641 gcttgtgaat agtgacaatc gattgaatac gagtactgta agaacaagga aaatcgatgg
    26701 gcgtattaaa gtaattaaaa ctgatgagaa tggccaaagg ctggcaggag caaaatttga
    26761 aattttatca agcgattcac aagtgataca agaaggtata acggcagaaa acggagaatt
    26821 tttaagtgaa ccgcttcctg taggtagcta tcaagtccga gaaacagaag caccggaagg
    26881 gtatctttta gatgcgacgg tacatgatgt ttttataaat gaatactcca tagaagaagt
    26941 gacgttaacc attgaaaaca tccttgatac gggtggtgtt gaactaatta aacatgctga
    27001 aggcagtggt gaagtccttc aaggagctgt ttttgagtta cagaaccgag aaggagaaac
    27061 gctacaaacc ggt
//
LOCUS       DAXLPY010000034        26866 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.034, whole genome shotgun sequence.
ACCESSION   DAXLPY010000034 DAXLPY010000000
VERSION     DAXLPY010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.034"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(20..967)
                     /locus_tag="ACF3UF_001550"
     CDS             complement(20..967)
                     /locus_tag="ACF3UF_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3671667.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(1096..1860)
                     /locus_tag="ACF3UF_001551"
     CDS             complement(1096..1860)
                     /locus_tag="ACF3UF_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3671668.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(1864..2253)
                     /locus_tag="ACF3UF_001552"
     CDS             complement(1864..2253)
                     /locus_tag="ACF3UF_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671669.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            2388..2930
                     /locus_tag="ACF3UF_001553"
     CDS             2388..2930
                     /locus_tag="ACF3UF_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFD3671670.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            3078..3710
                     /locus_tag="ACF3UF_001554"
     CDS             3078..3710
                     /locus_tag="ACF3UF_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671671.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(3844..3969)
                     /locus_tag="ACF3UF_001555"
     CDS             complement(3844..3969)
                     /locus_tag="ACF3UF_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFD3671672.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(4103..4996)
                     /locus_tag="ACF3UF_001556"
     CDS             complement(4103..4996)
                     /locus_tag="ACF3UF_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFD3671673.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(5178..6104)
                     /locus_tag="ACF3UF_001557"
     CDS             complement(5178..6104)
                     /locus_tag="ACF3UF_001557"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFD3671674.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(6189..6950)
                     /gene="pflA"
                     /locus_tag="ACF3UF_001558"
     CDS             complement(6189..6950)
                     /gene="pflA"
                     /locus_tag="ACF3UF_001558"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFD3671675.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(7194..9425)
                     /gene="pflB"
                     /locus_tag="ACF3UF_001559"
     CDS             complement(7194..9425)
                     /gene="pflB"
                     /locus_tag="ACF3UF_001559"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFD3671676.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(9702..12152)
                     /gene="parC"
                     /locus_tag="ACF3UF_001560"
     CDS             complement(9702..12152)
                     /gene="parC"
                     /locus_tag="ACF3UF_001560"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFD3671677.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(12164..14209)
                     /gene="parE"
                     /locus_tag="ACF3UF_001561"
     CDS             complement(12164..14209)
                     /gene="parE"
                     /locus_tag="ACF3UF_001561"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFD3671678.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(14375..14809)
                     /locus_tag="ACF3UF_001562"
     CDS             complement(14375..14809)
                     /locus_tag="ACF3UF_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFD3671679.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            14936..15574
                     /gene="plsY"
                     /locus_tag="ACF3UF_001563"
     CDS             14936..15574
                     /gene="plsY"
                     /locus_tag="ACF3UF_001563"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFD3671680.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(15706..16581)
                     /locus_tag="ACF3UF_001564"
     CDS             complement(15706..16581)
                     /locus_tag="ACF3UF_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFD3671681.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(16663..17454)
                     /gene="codY"
                     /locus_tag="ACF3UF_001565"
     CDS             complement(16663..17454)
                     /gene="codY"
                     /locus_tag="ACF3UF_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFD3671682.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(17472..18872)
                     /gene="hslU"
                     /locus_tag="ACF3UF_001566"
     CDS             complement(17472..18872)
                     /gene="hslU"
                     /locus_tag="ACF3UF_001566"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFD3671683.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(18886..19434)
                     /gene="hslV"
                     /locus_tag="ACF3UF_001567"
     CDS             complement(18886..19434)
                     /gene="hslV"
                     /locus_tag="ACF3UF_001567"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFD3671684.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(19471..20376)
                     /gene="xerC"
                     /locus_tag="ACF3UF_001568"
     CDS             complement(19471..20376)
                     /gene="xerC"
                     /locus_tag="ACF3UF_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFD3671685.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(20574..21950)
                     /gene="trmFO"
                     /locus_tag="ACF3UF_001569"
     CDS             complement(20574..21950)
                     /gene="trmFO"
                     /locus_tag="ACF3UF_001569"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFD3671686.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(21919..23997)
                     /gene="topA"
                     /locus_tag="ACF3UF_001570"
     CDS             complement(21919..23997)
                     /gene="topA"
                     /locus_tag="ACF3UF_001570"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFD3671687.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHGHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(24119..24976)
                     /gene="dprA"
                     /locus_tag="ACF3UF_001571"
     CDS             complement(24119..24976)
                     /gene="dprA"
                     /locus_tag="ACF3UF_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFD3671688.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(25032..25799)
                     /locus_tag="ACF3UF_001572"
     CDS             complement(25032..25799)
                     /locus_tag="ACF3UF_001572"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFD3671689.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(25792..26652)
                     /gene="ylqF"
                     /locus_tag="ACF3UF_001573"
     CDS             complement(25792..26652)
                     /gene="ylqF"
                     /locus_tag="ACF3UF_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFD3671690.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            complement(26746..>26866)
                     /locus_tag="ACF3UF_001574"
     CDS             complement(26746..>26866)
                     /locus_tag="ACF3UF_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3671691.1"
                     /translation="FIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         7147 a         5754 c         4595 g         9370 t
ORIGIN      
        1 atatatatag taataagact taattcgttg tctctctgat aactagttca ggaaaaaaac
       61 gacgataacc ttgactcgcc cctttttctt ctattttttt taacaacatt tctccacata
      121 cttcacccat acgtataata tcttgcttga tcgttgtcaa tttaggtgaa ctgatttggt
      181 ctaaaaatac cccatcaaat ccaatcacac caaattcttc gggcaagtgt cctccagcat
      241 ttataatccc tcttactgct cctagtgcta gccgatctga actacataca aaacaagttt
      301 tatctgtaaa atctgcccag ttttctgtca tatatctttc tacttctgtc gaatgatttg
      361 gaaaccgcaa gattttacta ggaagatcaa cttccttcat cacagataaa taaccagttt
      421 cccttgaaat ttcaaaaggc tcgtccactt cgataccgat ataaataatc gtttgataat
      481 ctctttctaa ggcatattgc gttgcttttg ctgtaccata ttcattatcg ctgtctacat
      541 aatcatatcc ttcagaattt tccccaaaca agacaactgg tttttccaaa cggtcgatcc
      601 aatcgaagtc tttttttctg acacctgtga tgatgtatcc atcacaagaa ccgacgtcga
      661 aggcatcatt tgtaactaat tggagagaat aatgcgcttt accgatccgt ttagcgattc
      721 ccatcagcaa attcatgtaa tagggctcag ttgtgtcgat ttcttccagt ataaataatt
      781 tgatgatctg cgaccgattc gtgacaagtg cttttgcagc aatatttgga cggtaatcca
      841 gttcagccat tgctgagaaa actaactctt tcaattcgtc agtcacctgt tccggatgat
      901 tgatgactcg agagaccgtc atttttgaaa cattggcacg ttttgcaaca tctgctaaag
      961 tgggcatgct ctcttccttt ctaacatgtt gtcattctta ctatcaatta taccaaattt
     1021 tcctaacaga gtttattata gcccaaaata aaaaacggaa aatcctctat cgtcatgagt
     1081 gattttccgt ttcaattatt tatacttttt tatcaaattt tttgctaaaa aagtggaagc
     1141 ttcttccatt agtggtattt gtaccatatg tcgctgtgtt tttgaggaac gaaaaacaat
     1201 ttcttttccg taagacttat gccgattttt ttctacaaat cgttccgttt gtatataagg
     1261 gattttttcg tcagcttgtc catgccaaaa gaacagagga cgtccagcta acttttccgg
     1321 ctgcaatgac aaatcatagc tcttaaccca tgaaatcaaa tcaaaatagt cttttggtac
     1381 gacataatta tattccgatg cgcgccttac gatttctttt ccatattcca aaggtgcagg
     1441 ggaacccatc aaacacacgc ccgctactat atgaggatgt ttagccaaca aggcgcatgt
     1501 tgtcattccc cccatcgaaa ccccgccaac tgcaagctga tcatgtagaa gacctctttt
     1561 ttctaaatgc ttgataagtg tgtcaaattc aaacagattt ccgtagatac tatcccaaaa
     1621 tgtataggat ggaatagaag aaaccggctg tttgcgctcc ccatgattca tcgcatctgg
     1681 caggatcaca cgaatgccct gctgcgcaat ttttcttcct tgcgtcaaaa ctaactcctt
     1741 acttgtctgc catccgtgat aatagatgac aacgggaata cgttcctctc ttaattcttt
     1801 cagaacaact tctaacactg gaatatgatg gacagaacgt ttcaatataa ttggattcaa
     1861 ttgttactca cctattttca ttaaatttcc tgatcgccat agcaaccatg ctccaacagt
     1921 tgtctggaac aggttcagtg taccaaataa tataaatgca ggactgaatg gctcgggaaa
     1981 taagcacaga gaacaaagtc ccaccactcc taatgctagc gaaaggagtg gataaataga
     2041 aaaattcaaa aaactggcaa cgctaccgaa aatattacca ataaacagta tcaaaaagaa
     2101 aaaaacgctt aaaattaaac catctgtcag cgacatctga aaaacaatgt tctctacctc
     2161 aattggctgt tgaatcgaat agacacctaa gtatatactg agaaggagac ttagcacgtg
     2221 gctggcacaa aacacacgat tgaccgtttt cattttaatc acctaaccta tctttataat
     2281 tctattataa tcattttatc atttttttgt atgtataaag tttcaatttt tcttcactta
     2341 cgattttttt tgatattgtt gttatataaa tgaaaggagt tttacaaatg attgatccaa
     2401 aaatgttggg gatgatcttc ctcattaatt ttgcttatat cactctgaac acgttacgtt
     2461 tcatgttgac aatgaaaggc tatcgactga ttgctccact tgtcagtatg gtcgagatca
     2521 cgatttatat cgtcggctta tcccttgttt tagatcgttt agataatcca ctgaatttat
     2581 ttgtctatgc gttaggttac gcagtaggta tcagtgtcgg aattttgatt gaagacaaat
     2641 tggcattagg atacatcatg gtcacaacga ttttgccagc aaatagcgca gaagataaaa
     2701 gtttgccggg tatactgaga gaacacggtt atggtgtgac acagacttct gcaatggggc
     2761 tggaaggtga gcggctagtt ctcgaaatac tttctcctag aaaaagcgaa cgtgaactgt
     2821 atcgcctgat caaagaaatc gaagagcgtg cttttatcat ttcttatgag ccaaaatata
     2881 tttcaggtgg tttctggact aaaaaagtga gaaaacgaca aggaaaataa ctcacaaact
     2941 taaaaactgt ctaatatcta aattaaattt taaatgttag acagttttta tttattattt
     3001 tgattaaaaa acatcgacat atactcatca atttgttatt atactttata tacttatcaa
     3061 tttaatttgg agatattatg gaaattcaac gtagaaccac taatttttta catttaggct
     3121 ctttttttgc aactttgacg atcttatttt ttctatgtta ttcatacctt aagacctcac
     3181 atgcgccttc tagtgcatta ggctggttgc ttttggatca ttctgatatc acagaagccg
     3241 aagaaaatcc gttttttttg attttgtctt ctctttgcgg cttactgttt tctgtttatt
     3301 tcggtgccta tttttttcat cgacatcctg gtacgttaaa cgaagcttca agcgtattga
     3361 ttgcatttaa aacgttttct tttttagcaa ttctttttta ttcgtttaat cacaatacgc
     3421 ttttcttctt tatcatgaat ggtttagtcg tgattttatc catttttact tattttattt
     3481 tttcactcat ttttagccaa ttgaaatgtc cgctcttctt tcgattagtt cctgtcacct
     3541 gttttattta cagcttgttt tccttttttg tccttgcttt aatgccactg accaaccctt
     3601 cgacgatcca agtcgcagga aatctgttgg atatgctctt catcgtcagt ctaggtgtat
     3661 ttatgtggca aagaaaaaac aaacaaaata aaaagcattt tgaagcctga ctattacgac
     3721 ttcataaatg cttttttagt tttaaacact tcaatctaaa agaataaccc aagattggat
     3781 aaattattaa tgactcgcca ttcgtttctt agtgattctg gattatcaaa tggacttcct
     3841 aatctaatca gctagttctt cccataaaat gccatacttg actgaatcat aatattgatt
     3901 atttaaaaat ctaacttttc ttatcactac ttcctttgtc attccacatt tctcaccatt
     3961 tttttgcatt cctttgtttc cagaccatgt agtgaatcta ataggtggta gataggcaaa
     4021 atactcaaat aattctttta accataaagg aagagaaagg ctcctcctgc aagagtcagt
     4081 ataatttttg cttactgctc tcttaggttt tactcactaa aactgttcca tattctttga
     4141 tataagaaaa tgcatgcggt ataaatttct tgctcagctc agaaaagatt tgtcgtttaa
     4201 gaaaggccat ttcctccatt gtcaatgaag gatccaatgt tggtaattca atctcaaaat
     4261 tgtttttttc gacaataggt aattctaatg tgaatgattc ttcttccttt atagtattcg
     4321 tcacaagtag agactgatgg aaaatactag gccggcgatt tttatattta ttcttacgta
     4381 tcctgtcaac gataacttct atttgatcaa aaaagtacga ttcatttacg tctccaataa
     4441 gttcggctaa ttctttgaat gccttcgtta caggaagctg attcttctgt acaaaaaagt
     4501 aattagccaa agtaagcggg aagtgttcta tagaggaaag tgtgataaaa cggtacttct
     4561 catttcctgc agttgtcctc agcaattctg tctctcggct gtttcttact ccataaaaat
     4621 acgcttcttt ccgttcatct tcgaaacaat acgcccaaat aacttctccc atcgctaatt
     4681 tttgttcatc aacagagagt ctcttcaatt gttcagctat ggtttcagca gccgaagtgg
     4741 cttgttgcaa gtaatcttta ggatcaaata ttggaaagtt caaatgatat cttcgttctt
     4801 ccctcttgat taatcctgca tcgatcaata aatcaagaaa atgggaaaat ttattttgcg
     4861 aaaattcttt tttcaattct cttagaatcg tttcttgttc tcgatgttca tatagataat
     4921 cggtcaatga agaaaaaagc ggatcatcgg tcagtttttg ataaaagttt tccttatttt
     4981 ttgaataata gttcatatat gttctctttt ctatccgttt tattttactt aaaaggcttt
     5041 tacgtaaaaa ggaggaagaa caagagtcat aattgactgt tattctcctc catttcttcg
     5101 gcctttagta tgttctatgt ttctttttat atcaatcgct tatccattca ttttgaatgc
     5161 ttcatactac catttgatta gctaaataca gccgtcaatt gaggtacgac ttgtttttta
     5221 cgtgaaacga cacctttaag caaagcacgg ttgttggtca aagttgtttg gaaagcttct
     5281 tctacttttt cttttccttt accagcaaca agtaattctg aatcactgtc taagatgttt
     5341 gtgacaacta atacgaacag atcgtagcca tttgctttca tttcatcttc cattgctgct
     5401 tctagctctg cttgtcgatc catcacttca ttaaggtcca ctgtattgac ttgagcgata
     5461 cgaacgttgg aactgcccat tgggaaactt tttgcatcca aatcaagaag aaccgcagct
     5521 gatttatcac ttagatttgt tcctgctttc aacatttcaa gtccataagt gtttagatcg
     5581 acttcagcga ttgctgcaag ttcttttgca gctgcttcat cttcaggcgt acatgttggt
     5641 gatttgaaca acaatgtatc tgaaatgata gctgagagca tgattcctgc gatttcttta
     5701 ggaattgtta cttggttttc tttatatagt tttaaaataa tcgtacttgt acatccaact
     5761 ggttctgcac gatagtacaa tggattagct gtttcaaagt ttgcaatacg atggtggtct
     5821 actacagcta aaatatttac ttcgctgata tctgaaatac tttgttggaa ttcattatga
     5881 tccacaagca tgacatctgc attttctgct ttagctgact ctactactcg tggtgcagat
     5941 agctgaaagt ggtctaatgc gtattgtgtt tcttcattag gtgtacctag agcaactgct
     6001 tctgtttctt tacctaattc attttgcaag tgtgaaaacg caatggctgc cccgattgca
     6061 tctgtatctg gattttggtg accaaaaact aaaatttttg acatgtcatt cgctcctttg
     6121 tgatttctcc tatttaataa tagcaaaaaa acggaaagaa gcaatactta tcttctttcc
     6181 gatgcgacct atcgcgttaa atattttgta tactcttctg tatgaagcaa tcgtttagca
     6241 ttttcgacac gttcttttgt aggtggttcg atcccttcta atggatattt caaaccaagt
     6301 gtttcccact tgtattttcc catcgtatga taaggaagaa tctctactct gtctacattt
     6361 gacaaggttt gaataaagtt gtctagtcgg atcaaatatt catcataatc acttcgctca
     6421 ggaactagta catggcgaat ccaaaccggt ttgttgattt ttgacaaata ttgagccatt
     6481 tctaaaatat tttcattgtc ccaatgcgtt agttttttat gctcttcatt atcgatgtgt
     6541 ttgatgtcaa ataacagtaa atctgtatac ttcatcaatt cttgaaaacg tgaaaagaaa
     6601 ggttcttcat acgtaaaagg ttttccgcat gtatccaatg tagtatgcat cttccgctct
     6661 tttgcttttt taaatagttc gatcaaaaaa tcgatctgca atagaggttc tccaccacta
     6721 acagtaatac cacctttatc tccccagtaa ggtctgaagc gttctgcttt atctaaaagt
     6781 tcatctgctg tgtattcttt ccctccgcca atattccaag tatctggatt gtgacaaaat
     6841 tggcaacgca tgcggcatcc ttgcataaac acgacaaagc gcagtccagg tccgtctact
     6901 gaaccgaaag tttcgataga atgaacatag ccgattgttt tttcttccat ttaagttcac
     6961 atcttttctt tgatttcatt ttaagtacaa gttagctgtc gaagcgaagc tttctgaaca
     7021 aaatttttcg caattgccgc ttcgttatgt gtaaaattta cagggacgga acatacaagt
     7081 cctgcccctg taaatcgttt ctttcaaata agcatactga ttattcgatt ttgatgcgat
     7141 ggctattcaa cgtcctttcg acgctaagtc gaaaaacttt tttcacgaac tttttacatt
     7201 ctgtcgtgtg aagttctcat caagacatct aattgttgtt ctcttgtcaa gtcacggaat
     7261 ttaactgcat aaccagatac ccggatcgtc aagttcggat atttcattgg attttccatt
     7321 gcatcacgca ataaatcatt actgaataca ttgacattca aatgataagc tccttttgag
     7381 aagtatccat ctaagacatt acgcaagttt tcgattcttg tatcttgttc ttttccaaga
     7441 cctgaaggat tgattgtttg ggtatttgaa attccatcca atgcacagcc gtaattcatt
     7501 ttagctgttg agttcaggct agctaataac ccactttgtt ccgcattgta acttggattt
     7561 gctcctggcg caagtggttt tccagcttca cggccatcag gagtatttcc tgtattttta
     7621 ccgtaaacaa catttgaagt aatcgtcaat aatgaagttg ttggttttga gttgcggtaa
     7681 gttttatgac gtttgatttg tcccatgaag tattccaaga tccatgaaac taattcatct
     7741 gcacggtcat catcatttcc gtatttaggg aagtcgccat ccacttcaaa atcaactgct
     7801 attccttttt cattacggat tgcttttact tttgcatatt tgatcgctga caagctgtct
     7861 gccgcatgag agatcccagc aatacctgta gcaaatgtgc gttgcaagtc agaatccatc
     7921 aaagccagct gagctgcttc ataagaatat ttatcatgca tataatgaat gatgttcaac
     7981 gtattgacat atagttctgc taaccaatcc atcatattca tgaagttatg tttcacttct
     8041 tcaaagtcta gtatttctga tgtgattgga cgatattctg gtccaacttg ggcgccagtc
     8101 acttcatcga ctccgccatt gatggcatat aatagtgttt tagccaagtt agcacgagcg
     8161 ccaaagaatt gcatgtcttt tccgacaact gttcctgata cacagcaagc aatcgcacaa
     8221 tcatcagaac cccattgttc acgaagctga ttatcatttt cgaattgaat cgaagaactt
     8281 tcgatagcga ttctgctagc atatgttctg aatccttctg gaaggtgttc agaatacaaa
     8341 acagtcaagt ttggttctgg tgaaggtccc atatttgtta atgtatgaag cagacggaaa
     8401 tcattctttg taactaatga acgaccatct aatcccatac ctgcaatgga taaagtagcc
     8461 cagataggga atcctgagaa taattggtta tattcaggtg tacgcgcgaa tttgaccata
     8521 cgtaatttca ttactaagtg gtcgatcaat tcttgtgctt ctttttctgt gattactcca
     8581 ttatccaaat cacgttggat atagatatca aggaatgctg agatacgtcc gattgacatc
     8641 gcagcaccat tttgtgattt gattgctgct aaatatccga agtatagcca ttggacagct
     8701 tcttttgcat ttgcagctgg tttagaaata tcatagccat atttcgcagc catttctttc
     8761 atttgcgcta atgcacgata ttgttcagtg atttcttcac gtaaacgaat cacttcttca
     8821 ctcattgtat gataaccagt catatcatga tcttttttct tttgttccat caaatagtcg
     8881 attccataca atgccacacg acgatagtca ccgatgatac gtccgcgacc gtaagcgtct
     8941 ggaagccctg taatgatttt gtttttacga gcagcacgca tttcagcagt ataagcgtca
     9001 aatacacctt gattatgtgt tttgcgccag tcagtgaaaa tatgtgtcaa ttcatcgttt
     9061 ggtgtatagc cattgctttt tagcgcattg ttagccatat tgattccgcc gaacggcatg
     9121 aatgcttgtt tcaaaggttt gtctgtctgt agaccgacga ttttttccaa atctttatcc
     9181 aaatagcctg catcgtgtga agtaatagtt gatacgattt ctgtgtccat atcatagaca
     9241 ccgttacgct cgaattggat atcatttaac ttttgcaatt catcccataa tttttctgtt
     9301 gcttctgttg ggccttccaa aaagctgtca tcaccgcgat attcagtgta gttattttga
     9361 ataaagtctc tagtgtctac gccttctttc catttggtac ctttaaatcc attccattgc
     9421 tccattgtat ggacctccta aatttctgtt ttatgtaaca gtttttacgt gattagtata
     9481 acacagcacc ctatctttgc aagggttttc ttgtttttta tttaacaatt tttatgtttt
     9541 atttacatat atttaaatca acgttgacat accaacattt aagcattgtg aacactttca
     9601 tctttttttg caaacgtata aggatttatt aaaaatgaat gaaaaagaga cgccacctgt
     9661 attaatacag atggcgtctc ttcattaaaa tactacaaca gttacgactc gatgaaaatc
     9721 tcaggagcat cgataacttc gatgacttct ccaccttttt tctcatccat cgcaaatgat
     9781 ccattcgatg ttcgatcacc tatagggaaa tcagttgggt caatcgttaa ctgctgccct
     9841 ttttgattca tcaaggttat ttcttttgat cttccttccg acatatagat aatacggtgc
     9901 ggattttttt tcagctcacg catgaccgtc actccccgct tcgcacgtga agtttggctg
     9961 atttcttgag caagcatgcg tttaacagct cctcgctgag taacgattac gatcggcgta
    10021 tcaccttctg ctaacacaag cagcccgttg ataatcctat ctccatcttt caaattcata
    10081 gacttcactc cagctgcctt tgctccaaca acgggaacat ctgttaaagg atagcgcaaa
    10141 cccattcctt gatgcgttac taagaaaaca tctaagcctg gctgatcttc tttcagatac
    10201 acagcaatca gttcatcttc ttccgccttt agcttcatac agctgagcgg acggctctta
    10261 taggtgcgcc atggttcgaa ctctgtcatt cgtgtttgct tgatcaatcc attcttgctg
    10321 atgaatacaa atgttttctc tgcttgaatt ttttgatatg ggaaaacagc taaaatcgat
    10381 tcgtctacag acagattgga gattgtttga gaaatgtgct caccagcatc tttccatttc
    10441 aaatcgggta gttcatggac agggcggtag atcacatttg ctttatttgt gatcagaaga
    10501 acatggtcca atgtactcaa ttcacctgag tatagcaagt agtcgccttc tcgcatcccg
    10561 atttcttctg gtttggaagc actataagaa cgaaggcttg ttcgcttcac atagccttct
    10621 cgcgtcacac tgacaattac gtcttcttgt gccactaaga cttgcgtatc aattttgatt
    10681 tcttcgattt cgtcttcgat tgtcgttaga cgagcggaag aataattttt tttcacttct
    10741 cgcaattctt ttttcataac agagaaaagc tctttgtcat ttgaaaggat tttattcaac
    10801 tctgtgattt gcgcaatcaa gctttcggat tccttttgaa gctctgtgat atccgtgttc
    10861 gtcaaacggt ataattgcaa tgtgacaatt gcttctgctt gttcttctgt aaattgaaag
    10921 acgtcgacta aattcttttt ggcgtctttt ttgtctttac tttcacgaat cgttgcgatt
    10981 acttcatcca gaatcgataa agctttcatc aatccttcta cgatatgctg tcttttttga
    11041 gctttggcta aatcgaattg actacgtttt gttatgactt gctttcgatg ctcgatataa
    11101 cttcttaaaa tgtctttcag tccaacttga tgcggagtca tatggtcgat agcgaccata
    11161 ttgaaattgt aattgatctg tagctcagtg tttttgaaca aataattcaa aattccttga
    11221 gcattggcgt cttttttcaa ttcgacgaca atttgcagac ctgttctatc actttcatct
    11281 cgtacttcag ctattccatc gattttctta ttcaaacgga tctcatccat ttttttcacc
    11341 aaggtcgctt tatttacttc atatgggatt tctgtgatca cgatttgctg tttattaccc
    11401 ttcattgcct ctatctttgt tttcgaacga agaataactt ttcctcgtcc tgtttcataa
    11461 gcttttttga tttcatcttt tccttgcaag atccctcctg ttggaaagtc aggtccagga
    11521 atatattcca tcaatttttc aaggctcgct tgtggatgat cgatcatata gattgtgcca
    11581 tcgatcactt cagctaagtt atgagtcggg atttctgttg catatccagc agatatacct
    11641 gtcgatccat tgacgagaag gtttgggtat cgagctggaa ggactgttgg ttctttttct
    11701 gtatcatcaa aattccacac gagatcgact gtttctttct cgatatctgc tagcatctct
    11761 ccacttaact tggataatct ggcttcagta taacgcatcg cagcaggtgg atcaccgtcc
    11821 atactcccgt tattcccgtg catttcgatc agtacttccc gcaacttcca gtcttggctc
    11881 atgcggacca tcgcttcata aatactgatg tcaccatgag gatgataatt ccccatgata
    11941 tttccgacag attttgctga tttacggaat cctttgtcat acgtattgcc atctttgttc
    12001 atggcaaata atatccggcg ttgcactggc ttcaatccat cacggatatc aggcagtgca
    12061 cgttcttgga taatatattt ggaataacgt ccgaagcggt cacccatcac ttcttctaaa
    12121 gttaattctt gtacttcttg tcgattttcc atcaggtgac ctcctattct acttcaaata
    12181 actgattgtt ttcattttta tctgctcgtt cttcatctaa taaatcatta gaaactgaag
    12241 gagagatttc agtatcctct tttttatcta agatactgcc atcttcttcg agcgtaaatt
    12301 gcacgtgatt ttcgatccat tttcttcgag gttctacttt gtcacccatc agtgtggtta
    12361 ctcgacgttc agcttgcgca gcatcatcga tacggacgcg gatcaacgta cgggaagtcg
    12421 gatccatcgt tgtttcccac aattgttccg cattcatctc tccaagtcct ttatatcgct
    12481 gcagcatata tcctttgccg acttttttaa tcattgctgc caattcgtca tctgtccacg
    12541 catattcaat gacttgcttc tttccttgtc ctttggatac tttatataaa ggcggtaacg
    12601 cgatatatac tttcccagct tcaatcagcg gtttcatata acgataaaag aaagtaagca
    12661 gtaatacttg aatatgggcg ccgtctgtat ccgcatcggt catgatgatt actttgtcgt
    12721 aattacagtc ttcgatagaa aactcaggac cgactcctgc accaatcgta tagatcatcg
    12781 tattgatttc ttcatttttc aagatatctt gcattttagc tttttcggta ttgatgactt
    12841 ttcctcgtaa aggtagaatt gcttggaact ttctgtctct tccttgttta gcagatccgc
    12901 cagcagaatc cccttcgact aaatacaatt catttttctt agggtttcgg gattgtgcgg
    12961 gtgtcaattt tcctgaaaga agagattcgc cttttttacg cttcttccca tttcggcttt
    13021 cttctctggc tttacgtgct gcttctctcg cttctctggc tttgattgct ttacggacca
    13081 acatctggct catttcgcta ttttcctgca aataaaagcc catttgttca ctgatgacgt
    13141 tatctactac ggtacgagca actggcgtac caagtttttc ttttgtttgc ccttcaaatt
    13201 gcagaagatt ttcaggtaca cggatagaaa gtacagcagc taacccttct ctgaaatcac
    13261 taccttccag attcttgtcc cgttctttca gcaaaccaac ttttctcgca tattcattat
    13321 aagatttcgt catcgccgct ttcataccag cttcatgggt tcccccatct tttgtccgaa
    13381 cgttattgac aaaagataaa acattttctg aataaccgtc attgtattga taagcgacct
    13441 ctacttcgat accttctttt tctcctgaaa aataaacaac tggtgtcaat gtatcttttt
    13501 cttcattcag ataatcaaca aattctttga ttccttcttc gtaatgaaaa atttccttga
    13561 ctggttcttc tccacgaaga tcagaaagag agattttaac gccttttaga agaaaggcag
    13621 attctcttaa ccgttcggct aaaatttcat atgaaaattt cgttgtactg aatattgtat
    13681 catctggtaa aaaatggaca gtcgtcccgt ttgctttttt tgtttttcct atctttttca
    13741 aagtaccgtc aggtttaccg ccgtttttaa atttctgctg atactctacg ccatctctaa
    13801 cgatcgttac aattagccat ttcgataagg catttaccac actggctcct acaccgtgca
    13861 gtccaccaga agttttgtac cctccttgac caaactttcc gccagcatgc agcacagtaa
    13921 aaatcacttc aactgttggt attccggaag catgcattcc tacaggcatc ccacgtccgc
    13981 tatctgcaac agttatacta ttgtcttcat ggatggtcac atcaatctca ctgccataac
    14041 ctgataatgc ttcgtcaact gcattatcga cgatttcata gactaaatga tgcaagcctc
    14101 ggctgtcagt ggatccaatg tacatccctg gtctttttct aactgcctct aatccttcca
    14161 atacttggat ggacgagtca ttgtattcgt tgtttacttt ttttgccaag gcaaacgctc
    14221 cttcaataat actttgcggc aaaaccgcac cacgattatc atactagaaa aggtcgtgaa
    14281 aaaaaagagg gtagacgaga aatcaatttt aattatctcc taaccgcttt ttcgacattc
    14341 ccctctatcg atcatctctt ctttgtggtc atttttattt ttggttttct ttcaacttac
    14401 caagttcaat cttaatacaa cgatccatta cgatatctgt acgtcctgct tttcttagca
    14461 tctcagctgc ttctttgttt tcaatcccta attgtgccca gaacacttta gcatcagttt
    14521 tcaaaaaatc acctgctatt tcaggtaaaa attcactccg tctaaataca tctacgatat
    14581 cgattggatc atcgatttct gtcaaattcg catagacttt ctcgcctaga atttcttcac
    14641 cagccaataa tggatttact ggtatgattt tatatccatt gtcttgcaat acctgtgcaa
    14701 ccatgtaact tgttcgttct ggtttattgc tcaagcctac gacggcaata ttttttgctt
    14761 cttccaaata gttgaaaatc gtttcttgtg ttggattttt tacagacatt tctgccaccc
    14821 cttgcttttc tttttattcc atctattata cttgtatctt tcattttttc aattgttcct
    14881 gttacctatt catgctaaaa taaaggatag ttttcaactt gaaagagggt aaaaaatgaa
    14941 attgatctta ttacttattt tagcatatct tttaggttct attccttccg gtgtctggat
    15001 tggcaaattg tttttcaaaa aagatatccg acaacacggg agcggtaata ctggaacgac
    15061 caatacattt cgtgtattag gcaaaacagc cgggattgtt gtcctgctta tggatatttt
    15121 aaaaggtaca ttggctactt gtttgccgat gatcttccac ctttctggga ttaaccctct
    15181 ttggtttggg gtatgcgcca ttcttggcca tacatttccg atttttgctg ggttcaaagg
    15241 aggaaaagct gttgcgacaa gtgcaggaat gcttttagga tttaatcctg tattttttgt
    15301 ttattcttgt atcatcttta tcgttagttt attttgtaca agtatggtga gtttgagcag
    15361 tatgatcagt gcagtattga tcactttatc tacgatcgtc cttccttatg tagctcctgt
    15421 gattttggct aagcccaatt ggttactgac gatcattgcc tttttagttt cttcctttat
    15481 cttttatcgg cataaagaca atatcaagcg tatcagaaac catactgaaa gtcgaatccc
    15541 gtttggtttg aatagcagca agaaaaaatc ctgatacttt ttcattccaa agagataaaa
    15601 cgggagtgtg acaaatcgat gtcacactcc cttattactt acaggatagc ttttttacac
    15661 accttggtaa acggtgttcc ctgctaactt ctcggtcaca acctcttact tcactgtgat
    15721 ggaatatttt gtcttgaaga tttcatgggc acctagttga ttgatcccta ctttttccat
    15781 caagtttcca ctactgttca ccgtgtcagc gattccgcac cacggttcga tacaaacgaa
    15841 aggcgcttct tttggataag gagaccagat ccctacataa ggcatatctt tatagcttaa
    15901 agttacgcta tgggaagatt tttcacttcg aatggcgtac gcatttagac cccttgtttc
    15961 aaaaaccaag gcatcttgct caaaaagttc acgattcaaa gccagattcg tatttgtctg
    16021 acctaacgtc ttttgatcca tatcgatgaa tgggcctttc aatggtaggc gtaatcttga
    16081 tttcaatgga gaaaatgcca gatagaaatc ttcaaatgac aatccttctt caagaggtac
    16141 attgaaagca ggatgtccac cgatagaaaa gaacatttct ttttcaccgg tatttgccac
    16201 ttgataatga accgtgatgc cgtctcctcc taattcatag ctgatcacta attcaaaatc
    16261 aaatggatac ttttctaatg tctccggcgt actccttaag atgaaactag ccatttcttg
    16321 tccatgttca atgacttcaa aatccatatc ccgagcaaat ccgtgttgcc ccatttgata
    16381 tgttttccct tgataaacat actgatcatc ttttaaacgt ccaacaaaag ggaataaaac
    16441 cggtgcatgt ctgccccaat acgctggatc accttgccag atatactcta aaccatgttc
    16501 ttttgatttc agactgatca attccgcacc gtgttcagcg atttcggcga tcagctggtc
    16561 attttgaata ataacagtca ttgccattcc tccaacttcg acttactttt taaaatggga
    16621 aggctggaac aaacatttct atctgcccca gtccccttac ttctaataac tgtgttttgc
    16681 taactcgtct ttaaaacggg aattcaatac ttttaaataa gttcccttca tgcctaacga
    16741 acgagattca atgattccag ctgattccaa ttttcgtaaa gcattgacga tcacagaacg
    16801 agtgatgccg atactatcgg caatattaga agcagtcaga cgaccttcat ctccatccaa
    16861 tgcttcaaag atagcttgta cagccttcaa ttcgctataa gataatgtgt tgattgccat
    16921 ttggacagcc gttgcactcc gtacatctgc ttcgatgctt cgagacttct gataaaggat
    16981 ctgcataccg acaaccgtag ctccatattc tgctaagact agatcgtcat ctgcaaacga
    17041 ttgttccata cgagataaga taatcgtacc caaacgttcg ccagctccaa agatcggaac
    17101 gacagtcgtc agaccaaatg gatatttctc tcttgactct accggaaatg cagtaatatc
    17161 actagtaatt gggatattag cttcagtttt catcaactgt gccactgtat cagtataaga
    17221 ttcaggaaat tgtttctcaa caaacattgt tttgattcgt tcattgttca catcgtgacg
    17281 ttcattataa cctagtaata ctccgtcact tcctatgata taggtgttgc tgtcaagaat
    17341 accacctagt gtgacagcca ttttatcgta aggcaaatct gcttgcatgt caaaagtatt
    17401 cttttgctgc aaaagtgtgt ttatcttgcg ggttttcgtt agcaagtctg tcattgtcgt
    17461 cctccgattt tttataaaat atagcgactt aaatcttcat ttgccgcaat tgagccaagt
    17521 ttgtcatcca catatgcttc tgtgatcgtt atttctccca tttgcatatc tggtgcttca
    17581 aataatagat cttctagtag tttttccaaa atggtatgca gtctgcgtgc gccgatatta
    17641 tctgtgtcac ggttgacatc gaaagcgatt tgagcgatcc gttcaattgc ttcttttgta
    17701 aacgtaactg acacattttc tgtaccgatc aacgcgacgt attgttttac taaagcatta
    17761 tttggttcgg tcagaatctt cacaaaatct tcagctgtca aatcatctaa ttctacccgt
    17821 atcgggaagc gtccttgaag ttctggaatt agatcacttg gtttagacaa atggaaagct
    17881 cctgaagcaa tgaataggac gtgatctgtt tggatgatcc cgtattttgt gtttacttgt
    17941 gaaccttcga caattggcaa tatgtctctt tggacgcctt ctctggatac ttctccagat
    18001 tgctgtgatt tagaagtgat cttatcgatt tcatcgataa aaataattcc actttcttcc
    18061 gctaatttga ttgcctcact atggatatca gcatccttga ctaattttgc tgattcttcc
    18121 ttgatcaata actctaaagc ttctttgact gttaccgtcc gttccacttt tttcttcggt
    18181 gtcaaagcac ctagagtttc atttaggtcg atccccattt gctccaatcc attgttcatc
    18241 attggtgcag gtttcttttg gtcttcaact tcaatggtta cttcacgact atccagtaaa
    18301 cccttttgta gttgttccaa gactgtacgg cgattgattc gaatatcttc tgtcacttct
    18361 tcttgcggtt cagcggtatt ttgctgacta gcattaaaaa gattcatcat ttgttcaaat
    18421 tgattagtgg attgtttctg ttcttttttg ataccaggta ccaagatttt taccaaacgt
    18481 ttttctgcat tttttttagc acttgtgtat acacggctgt actgctcttt ttctacgatt
    18541 tggatcgcat tttctactaa atcccgaacc attgattcta catctcttcc gacataaccg
    18601 acttcagtaa attttgttgc ttcgactttg acaaatggtg cattgacgat ttttgccaaa
    18661 cgtcgtgcga tttctgtttt accgacccct gtaggtccga tcatcagcat attttttggt
    18721 gtaatatctt gttgcatttt ttcatctaac tgcaaacggc gatagcggtt acgcaaagca
    18781 acggcaacag atttttttgc tgcgtgctgt cctacgatat attcatctaa ttcacttacg
    18841 atttgtcttg gtgtttgttt taattcatac atatctactc acctcttaca gttcttctac
    18901 gataatatta tgattagtaa agatacagat atctgcggca atatttaacg cattttctgc
    18961 aatttctttc gcactcatgt cgttttgagc atagtttttc attgctcggg ctgcagccaa
    19021 cgcaaaattc cctcctgatc cgatagctaa gataccatca tctggtgtga taacttctcc
    19081 tgtacctgaa acaagaagca tttctttatc attcattacg atcagcatcg cttcaagttt
    19141 ttgcatagat tgctgtgtcc gccattcttg agctaattcg acagctgcgc gttgtagatt
    19201 cccgttatat tcgtttagtt tgccttcaaa tttttcttct aaagtaaacg catctgcaac
    19261 acttccggcg aaacctacaa caacttctcc attgtagata cgtcgtactt tctttgcagt
    19321 gcctttcatg acaacagatt cacccattgt tacttggcca tctccagcca tagcaaattt
    19381 cccgtctttt tcgacggcac agatagtggt tgaatgaaat ggtgattcga ccatgtttgt
    19441 ttcctcctaa atttgttctt ttccttattt ttacgctctt ggatggaaag aacgatagtt
    19501 tttttgtaaa ctttcttttg ttacatgggc atagatctgg gtagtcgata aattggcatg
    19561 tcctagcaat tcttggactg tccgcaaatc tgccccatta tttaataaat gagtagcaaa
    19621 tgtatggcgc agcatgtgag gatggatatc actatccaaa ctgctttttt tgatcatttg
    19681 attcaagaca tattcaattc cagtaggcgt gattggtttt ccatgatgat tcacaaaaac
    19741 gatatcatgc tcttcgtgat attttgtcat caatacctgg cggccttccc tgaaatattc
    19801 ttgcagagca tcttgagcaa aagaacctag aggagcatat ctctctttgt tccctttacc
    19861 atggatcaac atgacctctg aatcaaaatc aatgtctgat accgacaaac tgctacactc
    19921 acttaaacgg atgcctgacc cgtaaaggac ttccagtaaa gcgcggttcc tcaaatccaa
    19981 aggactatct cctgctacgc tgtcaaaaag tgcttgcatt tcattttcat aaaaaaaacg
    20041 tggcagtctc aaatttttct ttttgagatg aacgtaagaa aatggatttt cttttatcac
    20101 ttcttctttg agaagatact gataaaacga acgtaggctg gctatcttgc gactgataga
    20161 atttctgcta tagctaggac gatgatcagc taatgcactc aaatagacac gaaccgtaaa
    20221 atattccgcc ttcagcagat cagcgtctcc agattcctcc aaaaaatgtt tgaaatggag
    20281 aatgtcttct tcatatgctt ctttcgtttt ttctgaatat cctctttcga caatcaaata
    20341 acgcaaaaat ttttgttccc acgtggcttc tgtcattttc tcaccttcct tttgtcccag
    20401 agaataattt agcacagcgt ttataaaaag acaaataaat tgtcagaatt taaccaatat
    20461 ttctaagttt gttcacaatt ggcgcaattc ctcacatttt gtttgagaaa ttcttaagaa
    20521 aaacgcaaga aaaagagcga gactatccgt ctcaccctct tcatggagtt tccttactca
    20581 tttgggattg cagttttttc taattctgtt tttattgcct cattagcttt taaagctcgt
    20641 tgtgcaattg cttcatatct tgcttttttg tctcgaatgc gctctggcag ttcaggaaac
    20701 agaccatagt tggcattcat cggttggaaa tgttttcctt ccgcatgagt aatgtagtaa
    20761 gccatacttc caatagctgt ttcttgtgga aactcgactg gttccatttc ttttgctaag
    20821 cgtgcggcgt tgattccagc aagtagtccg ctcgctgcac tttcaacata gccttctaca
    20881 ccagtcatct gacctgcaaa gaacagatct tcgcgtttcg ttgattggta agtcggtttc
    20941 agcaattctg gcgaattcat aaagctgttt cggtgcatca caccatagcg aacgaattca
    21001 gcattttcta acccaggaat catccggaaa acacgttttt gctcgcccca tttcaagtga
    21061 gtctgaaagc ccacgatgtt gtataaagaa gctgcagcat tgtcttgacg cagctggata
    21121 acagcataag gacgtttgcc agttttagga tcttccaatc caactggttt cataggtccg
    21181 aaaagcatcg ttttgaatcc tcgctgtgcc attacttcaa ttggcataca tccttcaaaa
    21241 tatttttctt tctcaaaaga tttaagttct gccacttcgg cattgattag tgcctcatgg
    21301 aaagctttga attcctcttc tgtcatcgga cagttcaagt aagctgcttc tcctttgtca
    21361 tagcgggact tcaaatatac tttatccata tcgatcgtag ctttgtctac gattggtgca
    21421 gctgcatcat agaaataaaa accatctgaa ccattgaatg ctttgatgct ttctgctaat
    21481 ggatgagaag tcaaaggtcc tgttgctact acggtgattc cttccggtat ttcagtaatt
    21541 tcttcgttta tcactgttac taatggatgc tctttgactt ttcgggtaat tgtttcagaa
    21601 aaagaatcgc ggtcaacagc taaggcacca ccagctggca ctgctgtttc atctgccgaa
    21661 gtgattacta ccgaattcaa tcggcgcatt tcttctttca ataaccctac tgcattagcc
    21721 aaactgtttc ctcttaatga attggaacat actagttcag caaaattact tgtgtgatgc
    21781 gcctcagtcg atttgactgg acgcatttca tataaacgga cagggactcc tgcttgtgcg
    21841 atctgccaag cagcttcact tccggcaagc cctgctccaa caacatttac cattttcaat
    21901 gaaagaacct cttttctatt atttttggat gtcttcttcg taatctccat ttacacagac
    21961 tacttgttta ccgcctttga ctttcttctc gaccagatat ccgtcacatt ttggacaatt
    22021 tctgcccact ggtttatccc aagaagtgaa ttcacattct gggaaacggg aacaaccata
    22081 gaatagtctg tttttcttag attttcgttc aatgacttgt ccttcatgac atactgggca
    22141 agtcacaccg atttctttta cgattggttt cgtattccga caatcaggaa aattactgca
    22201 agcataaaac ttcccatatt tccctaattt tatcaccatc ggatgtccac agacatcaca
    22261 atcgaatcct gctggttcat ctttgatttg aattttttcg attttttctt ccgcattcgt
    22321 cagttctttt tcaaacggtt tatagaaacg atcaaccact ttgacccacg cttccgtgcc
    22381 ttcttcaatt ttatccaaat ctccttccat ttctgctgtg aaatggatat cgacgatttg
    22441 agggaagaat tcacagatta atgaattgac aatttctcct agttcagtcg gctcaaatct
    22501 tttttgtgtc aattttacat agtagcgtct ttggatcgta tcaagtgttg gtgcataagt
    22561 ggaaggtcgc cctaccccgt tttcttctag tgcacgaatc aacgtagcct cactaaaacg
    22621 tgctggtggt tgagtaaaat gttgttttgg ttcaatatca acagattgga ctacatcgcc
    22681 ttcttcaagt tctggaagaa tattttcttt ctcttctttg ccgtcatctc taccttccac
    22741 atacacttgc atgaatcctt tgaatttgat ttttgaaccg ttcgcaatga agatgacacc
    22801 attttgttct aatgtcactt tcattgtatc taaaatagct ggtgtcatct gactagccac
    22861 aaaacgtgac cagatcaatg tataaagttt caattgatct ttatctaaat attgtttgag
    22921 ttcatctggt gtacgaagca cactcgttgg acgcacagct tcatgggcat cttgtgcgcc
    22981 ttgagcattt ttgatctttc ggtgaccatg tctagaaaat tcttttccat acgtatcttc
    23041 aataaatgct gcggcctctg cttttgctgt atcggcaatc cgggtagaat cagtacgcat
    23101 gtatgtaatc aagccgactg ttccttgttt acccaaagtg attccttcat ataattgctg
    23161 tgctaccatc atggtttttc ttgttcgaaa gtttaactta cgggcagctt cttgttgcag
    23221 gctacttgta gtgaaaggat tcgcagggtt tcttttgcgc tctttctttt ctactttttt
    23281 aacttcgaag tctgttccat caattctagc agtgacttct tttacacttt gtgcatctgg
    23341 taatttcttt ttcttaccgt cgattcccca gaaatttgct ttgaatttct tgcgagcttt
    23401 tttaaaatta ccgtcgatgc tccaatattc ttctggaaca aattctcgga tctctttttc
    23461 acggtcaata ataattttta aagcgacaga ttggacacgt cctgcactta accctttctt
    23521 gaccttacgc cagagaatag gactgatcga ataaccaacg attctgtcta aggtacgacg
    23581 agcttgctgt gcatctacta aatctacatc gatcgttctt ggttccttaa aagctgcttt
    23641 gactgcgtct tttgtgattt cattgaagac cacccgattt ttttctttca gatccaaccc
    23701 aagtaggtac gctaaatgcc aagcaatcgc ttctccttct ctatccgggt cacttgccaa
    23761 gtaaactttt tgagcttttt ttgctgcggc tttcaggctt ttgatgacat cgccttttcc
    23821 gcgtatagaa atataatggg gttcataatt gttttcaaaa tcgataccca ttttactttt
    23881 cggtaaatct cttatatggc caacactggc cattacttta tagtttcgtc caagatattt
    23941 ctcaattgtc ttggcttttg caggtgattc tacaatcact aaatatttat acgccattac
    24001 tgaatggact cctttccatt gtcgtgttcc tactattaaa agaggattca tacaaatcgt
    24061 agctaatcat atccattcag aaaacgtttg tcaagaaaag caaatgaaaa gtatggtgtt
    24121 attctttaaa ttctgccaag atatcttcac ccgaaaccgt gcaaactgca ccgtcttgga
    24181 tcaaatgatg acatccggta gaatgttctg ttaaaatatt tcctggaaca gaaaaaactg
    24241 ttcttccaag atccaatgct tgctgtgctg ttatcagaga gccgcttttt ttcttggctt
    24301 caaagacaca tgttccttta gacaaagctg cgataatccg atttctcatt ggaaaacaat
    24361 gctttttcgg gccggattga ggaggatatt cactcaaaag aagatgatca tttgcaatca
    24421 cctcttgcaa gtcacgattt tcagcaggat agacttgctc tatccctgtt ccaatgactg
    24481 cgattgtccg tccaccatga gagattgctg cttggtgacc gtatgtatct atccctttcg
    24541 cgcagccact gacgatcaca tatccagctt ctatcactgg ttttagtaaa taataaactg
    24601 tttttttggc taaagcagaa gtgtgtcttc caccaacaac gcttaacatg ttacaagaaa
    24661 gtaaagatag atcaccatta taaaacagta caattggcgg ataggtcaag tgaagcagct
    24721 gagggggata tttgggatca aagcaagtga taaacgactg tttcgattgg attttgcccc
    24781 agttagcgtg aatttcctgc caacttttgc gaaacagctc ccggtgtttg gttattttac
    24841 ctatcttaat gatgtcttca aatccgattt ctttataagg atactgcatc atccagttag
    24901 caagtgccca ttttccttga ctactgattc cttttgtata agcaagtttc aataaatttt
    24961 cttctatttg atacatcata aaaccgcctt tcgtctctct ttctaataag atacgtaaaa
    25021 gcggctgttt tttattgtaa atattttttt acaggtgcaa aacttttacg atggattggc
    25081 gtaattcctt gtcgttcaag tccttctaag tgttcctttg ttccataacc tgcattatgc
    25141 gagaaaccat atccaggata aagcacgtca tattctttca tcaattggtc tcgatatact
    25201 ttagcaatga tacttgcagc agcaatcgac acagatcgtg catccccttt gattattttt
    25261 tcctgctgaa taggcaaatc caaggtcatc gcatcgatca acaaatagct tggtacaatg
    25321 gacaattttt ctactgcttg gatcatcgct aatttacttg cttcataaat attcacatca
    25381 tcgattgtct gctgatcaac gatcccgatc ccgattgcca gggctttttc ttgaacttgt
    25441 tgataaagaa gttctcgctt tttctctgat aattgtttgg agtcattcag ccctaatatg
    25501 atctcatttt tcggcaagat aactgcagct gccacgacag gtccagctaa tggtcctctt
    25561 cctacttcat caatgccggc aatccattgg tgaccttgtg cgtacccttg cttttcaaag
    25621 caaaacattt cttcatattt ttccttaatt aatgcttcct ttttcaatcg tcgttcaaaa
    25681 gaagccagtg cttgctgcac gcctttgcgt ggatcatttc ttaatgattc tagtgtagga
    25741 tcatctattc tctgtatgct tttcaatcgt tctttgatac tttggatgga ttcagtcatc
    25801 acttttttgc tccatttctt cgcaacgatc cagtgtgtat cgtccaagtt ttccttgacg
    25861 aatatcatgc acgactaatt cgctgccacg atcatagtct tctttatacc cacgttttgc
    25921 tgtaatatcc atcagtaatt ccggtgccaa tttttcttct tgctcgattg ataaaccata
    25981 acgatcgctg attcttcctg aataatatcg ggcaaaaaag tctaatccgt aaatcgctaa
    26041 atcatctaaa tggacaagct ggtctttgat cgcgcctgtc agcgctagtt ttttgccgat
    26101 ttcttcatct tcaaatttgg gccataaaat ccctggtgtg tctaacaatt ccaactcatt
    26161 acctaaacga agccactgct gaccttttgt tacgccaggc ttatttcctg tctgtgcaat
    26221 tttcttgcct actagtcgat tcatcaacgt agatttccca acatttggaa tacctaagac
    26281 cattgcccga atagcgcgag gcttgatccc ccgagcagca tctcttgccc gtttttcttt
    26341 caatgcttct ttagccgcag gtactagacc tttaattcct ttactttctt gtgccgtgat
    26401 agctaatgca agatggcctt gtttacgaaa atattcttgc cacagctttg tctgttgtgg
    26461 atctgccaga tccgctttat tcaataaaac aaggcgaggt ttttgctgaa tgatctgatc
    26521 tagcattgga ttacgagaag ataaaggtaa tcgtgcgtct accaattcaa atacgatgtc
    26581 cacatatttc attttttcag aaacttctcg tcgggctttt gccatatgtc ccggaaacca
    26641 ttggatggtc attgttctct ccattccttt cataccggaa tattccccgg ctttacttgt
    26701 ttttttcttt ttcaatataa attcactttt ttattatctt aattgtcaaa ttaagttaga
    26761 caaatcatca atacttacgt aactcaaaaa tacttccaaa ggtgttcgat aattcagtga
    26821 ttttctagga atattatttc gtttcgatgc gacagattga ataaaa
//
LOCUS       DAXLPY010000035        26622 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.035, whole genome shotgun sequence.
ACCESSION   DAXLPY010000035 DAXLPY010000000
VERSION     DAXLPY010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.035"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            218..919
                     /locus_tag="ACF3UF_001575"
     CDS             218..919
                     /locus_tag="ACF3UF_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD3671692.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1528..2544)
                     /gene="tsaD"
                     /locus_tag="ACF3UF_001576"
     CDS             complement(1528..2544)
                     /gene="tsaD"
                     /locus_tag="ACF3UF_001576"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFD3671693.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2541..3005)
                     /gene="rimI"
                     /locus_tag="ACF3UF_001577"
     CDS             complement(2541..3005)
                     /gene="rimI"
                     /locus_tag="ACF3UF_001577"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFD3671694.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(3012..3554)
                     /gene="rimI"
                     /locus_tag="ACF3UF_001578"
     CDS             complement(3012..3554)
                     /gene="rimI"
                     /locus_tag="ACF3UF_001578"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFD3671695.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3538..4260)
                     /gene="tsaB"
                     /locus_tag="ACF3UF_001579"
     CDS             complement(3538..4260)
                     /gene="tsaB"
                     /locus_tag="ACF3UF_001579"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFD3671696.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4451..5431)
                     /locus_tag="ACF3UF_001580"
     CDS             complement(4451..5431)
                     /locus_tag="ACF3UF_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3671697.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5455..6939)
                     /gene="galT"
                     /locus_tag="ACF3UF_001581"
     CDS             complement(5455..6939)
                     /gene="galT"
                     /locus_tag="ACF3UF_001581"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFD3671698.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6951..7940)
                     /gene="galE"
                     /locus_tag="ACF3UF_001582"
     CDS             complement(6951..7940)
                     /gene="galE"
                     /locus_tag="ACF3UF_001582"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFD3671699.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            8188..8355
                     /locus_tag="ACF3UF_001583"
     CDS             8188..8355
                     /locus_tag="ACF3UF_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFD3671700.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8417..10228)
                     /locus_tag="ACF3UF_001584"
     CDS             complement(8417..10228)
                     /locus_tag="ACF3UF_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFD3671701.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10225..10590)
                     /locus_tag="ACF3UF_001585"
     CDS             complement(10225..10590)
                     /locus_tag="ACF3UF_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFD3671702.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(10753..11148)
                     /locus_tag="ACF3UF_001586"
     CDS             complement(10753..11148)
                     /locus_tag="ACF3UF_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFD3671703.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(11166..12128)
                     /locus_tag="ACF3UF_001587"
     CDS             complement(11166..12128)
                     /locus_tag="ACF3UF_001587"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFD3671704.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(12128..12340)
                     /locus_tag="ACF3UF_001588"
     CDS             complement(12128..12340)
                     /locus_tag="ACF3UF_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFD3671705.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(12361..13059)
                     /locus_tag="ACF3UF_001589"
     CDS             complement(12361..13059)
                     /locus_tag="ACF3UF_001589"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFD3671706.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(13079..13621)
                     /locus_tag="ACF3UF_001590"
     CDS             complement(13079..13621)
                     /locus_tag="ACF3UF_001590"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFD3671707.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(13753..14757)
                     /locus_tag="ACF3UF_001591"
     CDS             complement(13753..14757)
                     /locus_tag="ACF3UF_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFD3671708.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(14754..15743)
                     /locus_tag="ACF3UF_001592"
     CDS             complement(14754..15743)
                     /locus_tag="ACF3UF_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFD3671709.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(15740..16546)
                     /locus_tag="ACF3UF_001593"
     CDS             complement(15740..16546)
                     /locus_tag="ACF3UF_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671710.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            16712..17668
                     /locus_tag="ACF3UF_001594"
     CDS             16712..17668
                     /locus_tag="ACF3UF_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3671711.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(17745..18263)
                     /locus_tag="ACF3UF_001595"
     CDS             complement(17745..18263)
                     /locus_tag="ACF3UF_001595"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFD3671712.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18351..18500)
                     /gene="rpmG"
                     /locus_tag="ACF3UF_001596"
     CDS             complement(18351..18500)
                     /gene="rpmG"
                     /locus_tag="ACF3UF_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFD3671713.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18728..19174
                     /locus_tag="ACF3UF_001597"
     CDS             18728..19174
                     /locus_tag="ACF3UF_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFD3671714.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(19369..21264)
                     /gene="asnB"
                     /locus_tag="ACF3UF_001598"
     CDS             complement(19369..21264)
                     /gene="asnB"
                     /locus_tag="ACF3UF_001598"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFD3671715.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(21589..22563)
                     /gene="bsh"
                     /locus_tag="ACF3UF_001599"
     CDS             complement(21589..22563)
                     /gene="bsh"
                     /locus_tag="ACF3UF_001599"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFD3671716.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(22897..22984)
                     /locus_tag="ACF3UF_001600"
     tRNA            complement(22897..22984)
                     /locus_tag="ACF3UF_001600"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22950..22952),aa:Ser,seq:cga)
     gene            complement(23129..23695)
                     /locus_tag="ACF3UF_001601"
     CDS             complement(23129..23695)
                     /locus_tag="ACF3UF_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3671717.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            23951..25281
                     /locus_tag="ACF3UF_001602"
                     /pseudo
     CDS             23951..25281
                     /locus_tag="ACF3UF_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
     gene            25247..25597
                     /locus_tag="ACF3UF_001603"
     CDS             25247..25597
                     /locus_tag="ACF3UF_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671718.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(25689..26108)
                     /locus_tag="ACF3UF_001604"
                     /pseudo
     CDS             complement(25689..26108)
                     /locus_tag="ACF3UF_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(26109..26453)
                     /locus_tag="ACF3UF_001605"
     CDS             complement(26109..26453)
                     /locus_tag="ACF3UF_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFD3671719.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
BASE COUNT         7904 a         5541 c         4553 g         8624 t
ORIGIN      
        1 gttgttagcg tttactatat gtattattgt tgttttttat acacaaatca ttcgcttcaa
       61 aacaaattat tcaataccat tgtatatttt ttacataata acaaattata tttgtaaagt
      121 attaaaactt gtttctaatg ttggtatgtt aaaactttac aaattcttta aaaaaagtga
      181 caataaatat agtgaacaat aaggagagga ctttttaatg cgtgttaata aaatcgattt
      241 tcacttttca aaactcagat atcaacctga ttttgaacat ttctcggatg aagagttcca
      301 acagatcaag gaacatactg ttcttcgttc ttataaaaaa ggacagatcc ttttcgacga
      361 tggtgatccc agacaacggt tgtatatctt gaccaaagga ctcgttcgtt tagaacgtta
      421 tgatgaaagt gcaacttatt actactatga ctatgtgaat acaaataacc tttttcctat
      481 gtcaggaatg tttggagaag agacctacac ttatacagct caagcgatga ctgatattga
      541 aacattctac cttcctgttt cctactatga aaaattagca cgaaaaaatc ccgaacagtt
      601 gatctatatg atacaaaaaa tttctaaagt agttgaaata catgaattgc gtatccaaat
      661 cggattgacc tctagcgcct ttgaccgggt aaaacaaaat ttattcattt tgaaagaaga
      721 attgggcgta ccaacaaaag atggtcatat caccattcct tatccgatca ccttaaaaga
      781 attagcagtg aatagcggca cgacacgtga aactgctgga caagtaatca aacaactacg
      841 tgattccggg ctgttagatt atgacaaaaa gcgttttact ttctgtaaga cagctactac
      901 tccagctatg agagaataac gcgaacaaaa ataagcagtg accctgataa atatcagggt
      961 cactgcttat tttcctccct aaaacttctg aaagatccgg cagttttaga tcactggaca
     1021 agactcaaag attttctatg tgtgtttcag ttatgtaata ttcactgttt gcaaaaaata
     1081 ctgttagatt aactagatga agcgtcttgt cctcatccga tctagattat tcgatattcc
     1141 tcgacaataa acgattactc agtgagggca atcagaggaa cggataatga taaataagct
     1201 gtaaaaaata gcaaaataac aataatgatt aaaagtatgt aaaaaatagg gctttgacaa
     1261 aaacgtgtca cagccctatt tcgattaaac ggtgtgtacc tgtcaactct tcggtcacaa
     1321 gtcataatgt tcataaacat gaggagctgt tttttgaaat tgttccttgt gaatcagagt
     1381 taaacgacag gcttacgaac tcttgattaa acggcgttca aaagcttgca tacgcggtaa
     1441 taagaacagc caggtcaaaa acatgagaag ccgtttttcc tgggctgttc ttattacttg
     1501 atgcagggca gctttttcac aacctcttta ttcagataaa accaagcttg gatcagcatt
     1561 caactgatag ctagcaaaat ttcttttttg catttccaca tgtgctgctg ctccaatcat
     1621 tgcagcatta tctccacaaa gtcgaagagg gggaatcact agttctacct cagggagttt
     1681 agctgccaaa gcatcctgca atccttcacg caacccttga ttggccgcta cacctccagc
     1741 tataatcagt tgcttgactg gataattttg acaagctcga agtgttttag taatcaatac
     1801 atcgatcaca cttgcttgaa agctagctgc taaatcattt ttgtctagat cttctccacg
     1861 ctgttgtgca ttatgcacca aattgataaa tgcacttttt aatccgctaa aactgaaatc
     1921 ataattatct tcatggatca tcgctcgcgg aaaatggtaa ttatcttttc cctgatgagc
     1981 tagctgatcg atttcttttc cgcttgggta agaaagacct aatactcttc caactttgtc
     2041 ataagcttct cctgctgcgt catctcttgt ctccccaatg atttcatatg atccatcttc
     2101 ttgcatatag actaattctg tatgtcctcc gctaacaaga agtgccatca atggaaactg
     2161 gaatggttta accagacggg ctgcatagat atgccctgcc atatggttta caggaataag
     2221 cggcaattgg tgtgcccaag caaaagcctt agctgcagaa ataccaatca gcaacgagcc
     2281 gacaagtcct ggtccataag tgacagcgac tgccgataaa tcttctgccg acacaccagc
     2341 ttctaccagt gcatcttcca agcataaggt gatttgttct acgtgatggc ggctagctac
     2401 ttcaggtact acgccaccaa aacgtttatg actgtttatt tgagaagcaa cgatgttaga
     2461 taagatctct gttccatttc taacgaccgc tacactcgtt tcatcacaac ttgattcaat
     2521 cgccagaatc aattcttcat tcatttcatc gtctccgttt ttaactttct gctcataatg
     2581 atcgcatctt ccgtcggatt gcgataatat gatttccgtt tacctaatat acgaaacttt
     2641 tctgattcat aaagttttct tgctgcttca ttagatagac gtacttctaa aaaaacatgc
     2701 agcgaatctt ttatttgttc cgtaatcagt aattgtaaca aatgccgtgc atgccctttt
     2761 ccttgttctg aaactgcaac agcaatattt gtgatctcga cttcatctat tactttcgag
     2821 tatccaataa agccacagat ctggttatct tcagctaaaa gcagataatc agagtgaggc
     2881 tgttggatgt ctgccaaaaa ctgcattttc gtccaaggtg aaccatgtgg ataagcattt
     2941 tcgctaatca tccatacgca ttctgccaag tacgcttcat caaaatcttt ttttctgcaa
     3001 atcaactaat ctcactcatt ttctaaaagt tttatcatat ccaacgcatc ttcttttgtt
     3061 tcagtgtaat atcttttttt gatcgttgtt gcttgaaacc ccaatttccg ataaagtctt
     3121 tgtgcatctt gattactcat acgcacttct aatgacatcg tctcacagcg attcattata
     3181 gcaaagttct cgatttcgtc aataagcagc gaaccgattc gtttacgctg atatgccggt
     3241 cgaacggcaa tattcgtgat atggcaatct aaaccgaacg ctcttgaacc gataaaacca
     3301 atcattcttc cattatcaaa gatacctaga tatagatgag gaagcggtga cttcaattct
     3361 gatataaagg cactttttgt ccatggcaat tcgccattat agacttctcg ttcgacatcc
     3421 agcagctctt tgatatcttc tgtagtcaat tctcttagta cgtaacgacg atcgatttgt
     3481 tcgactgttt tttctgtata aatcatttta tcttgaaaaa agcttctggc atacgctcta
     3541 aattttttca acataacttt cgtctccagg tgtgtgcgtc tccaaccatt tttcttctgc
     3601 ttctactcgt tttaaatagc gaggaagaaa agcttgtttc tctgcaactg gttcaactaa
     3661 agcacctaat tgagccacag ttacaccact tggaatatcc catgctggaa ctgtattaat
     3721 catcgcacta ggcaatattt cctttatttc agagaagaat ttgtgacaat cactcccgac
     3781 gaaataaata gcttcattca gcttttgtag ttgtgtgaac aaatcagaag cagaaatatg
     3841 tacatcttca agtacagttt ctaatctatt ttctttccag cggtatgccc cagcgtatac
     3901 attttttctt cgagcatcaa acatgggcac aataatatta tccacaccga tgcaattagc
     3961 cgcgatggtt ttcagactag atactcctac tagctcttta tctaatgtat aagcaatcgt
     4021 ttttgctgtc gttacaccta tacgaagccc tgtataagaa ccgggaccat cagaaaccgc
     4081 gattcggtca atgtcttttg gacttatttg aagatctgca aacaattggt cgattgcagg
     4141 catcagtgtt acactgtggt tgcgtttgat atttgtttgt atttgtccaa gaatttgttc
     4201 gtcttctacc acaccgatcg ccaaagtttg gtttgcagta tctattccta atgtaatcat
     4261 atatttgatc ctttctgcta tgacattctc gccttccatt gtagcatact tttttattct
     4321 gaggatgaaa ataccaaagg caaaactagt acaataatac atgattatct gctggcgggc
     4381 aaattttgcc ccttcctgaa acacaaaaaa gctgcggtat cactccattt tcccacagct
     4441 tttccatctt ttatttcgtt gattctcgaa taatcaactc tgtttccaca ataatctttc
     4501 ttgaaaccgg tgctttggaa ttacttaatt gaagaatcgt ctccactgct agctctccca
     4561 tccattcggt ataaactttt acagtagaaa gcgagggcgt tacatatttc gctacactga
     4621 catcattgaa gcccatcaca gaaatatctt ctggtaccac taaacctttt tcttgaatcg
     4681 ctttcagtgc gccaatcgct aatgcatcat tagctgcaaa aagcgcatca ggaacatgcg
     4741 gattcgtttt taaatattgc ttcactgctt gatatcctga ctcgacagaa aaatctgctt
     4801 cgataattgg accttcgtcg tagccttttt ctgccaaaac ttgttgaaat gccataattc
     4861 tgggatcttt tagccgctga tggtttttct tcgtatattc tgttccagca agcatagcga
     4921 tatgttgcgc tttatgggag acaaagtgtt caatgacttt ttgaacactt gacttaaagt
     4981 cgacaactag agagtcgatt ccttgagaag tgccgtcaga atctaccaaa agcaaggcat
     5041 tttgggatcc tttcatttct aataactgag cttcgtcgaa ttttcctagt gcgatcgttc
     5101 catctgccgg aagatcacta atggaatccc acgtttcttt caataaagta acgtttgctt
     5161 cttctgcctt tttttcgatt cctaggcgaa tagataaata ataaagatct tcaagctctt
     5221 ccgtatcgtc gtaccactgg atcaggcgaa gcgtttgctt agtatttgct gcatttttac
     5281 gatgtttcgt ataatttaag cgttctgctg cttcaaaaat tttttgcttt gttgctaagc
     5341 caacggaaag atcaggatca tagttgagaa ctcttgaaac agtagcagga gaaactcctg
     5401 ccaactgcgc aatgtcttta attgttgcca tttgtctctc ctcctttttt acgtttataa
     5461 aatcgcagta aatcgttcaa acgctgcctg tcctttttca tctcgcttga atactccagc
     5521 gtcttccagt acacgtgcaa aaacctgacc tacagatttt tgtacgacat cggtgaccgt
     5581 atctttcgtc aaatcaggat gttctttttt taattgttct gcccacggac gatgatattc
     5641 agccatctgg ttttcttctc ctaataagaa atgctctact tctactagtt ctggtttcaa
     5701 acgaggtggt aaaacagcaa gccccattac ttcgatcaac ccaatgttct cctttttgat
     5761 atgttggaca tctttatgtg gatgaaaaat cccatcagga tgttcttctg aaacattgtt
     5821 gtctcgaagg acaaggtcca actcaaagta attgtccctt cttcgtgcaa ttggcgtaat
     5881 cgtatggtgt ggtgtaccat ctgctgaaaa agctctgata gatactgttt catccgaata
     5941 tgctttccat ttttccaata ctgagttagc tgcttcaata agcaagtttt tctctgttga
     6001 ttgcaaacgg atcacagaca tcggccattt cacgactcct gcgatgactt gcggataatc
     6061 ttctagtttg ataagttttt ctatcggtgc ttttgccata ggaaattcat gacgtcctgc
     6121 ctgataatga tcatgagaaa gaatcgatcc tccaacaatt ggtaagtcag cattcgaacc
     6181 aacaaagtaa tgaggcaaga cttcagtaat ccgaagcagt ctagcaaatg tttcctttgt
     6241 gattttcatc gggcggtgtt gttctgataa aatgatcgaa tgttcattgt aataagcata
     6301 aggggaatat tggaatcccc agctttcacc gtctagattc attcgaataa tccggtgatt
     6361 ggtgcgggct ggatagttca agcgacctct atatccttcg ttttccatgc aaagcatgca
     6421 ggtaggatag tctactttta ccgcctcgcg ttctgctgcg atttgttttg gatctttttc
     6481 tggcttagat aaattgattg tgatttccag ttcaccatac tccgactctg ccggaaattt
     6541 gatgtttttt gcgatggctc ttgttttgat gtagtcattt ttcttactta aattaaagaa
     6601 atactcagtt gcttcctctg ggcttttcga atagtgctgt gcaaagaatg cattgacgac
     6661 tgaaggtggc ggtgtgagaa aatccattaa ttgcgcttca aaaatctctt gttctgctgg
     6721 caattctgaa agaacaccat tttctcttgc cttagcgaca agctgatcca ataagtctac
     6781 agattcttcc ttaactggtc ttacttcaat gctttctaga gcatcttctc ctaccatccc
     6841 taaaagacga ttctgtaaat ataagcggtc catttccatc catccgccag cttcgatcgc
     6901 aagtgtggca aaatcacaaa tcgtttgact gattgacata tctcattccc ctattcttca
     6961 taaccatttg gatggctgac atgccaatcc catgctgttt tgataatcgc tttgatatct
     7021 gtgtattcag gtttccagcc cagaatctct ctcgcttttt cacttgaagc gactaatcgg
     7081 ctaggatctc cagctcttct tggtgctatt tctgctggaa tttcttttcc tgtcacttct
     7141 ctagctgctt ctagcatttc cttgactgag tatcctttgc tgctgcctaa attgaagaag
     7201 ttgctttcat ttccttcttt caagtattcc aaagctaaaa tatgtgcagc aatcaaatct
     7261 tctacttgaa cataatctct gatacatgtt ccatctggtg tatcataatc gtctccataa
     7321 acagccaagg cttttctttg accaagagct acttgtaaaa tgattgggac aagatgcgtt
     7381 tctggtgtat gatcttctcc gatagatgca tctgcttttg ctccggctac attgaagtag
     7441 cgcaaagcga catagcgcat gccatatgct tggtcacacc acttcatcat tttttccatc
     7501 atcaatttac tttcaccata cggattttta ggattagctg gtgtatcttc tgtgattgga
     7561 gactctttcg gctctccata agttgctgca gtagaagaga atacgatttt attcacgttg
     7621 aactcgtgca tgacttcaag taagatttgc ataccgtata cgttgttgtt gaaatacatc
     7681 aatggttttt cgacagattc tcctactaaa gagcttgcag caaaatggat tactccttca
     7741 atcggttcct tttcaaatac ggaacgtaga aattctttat cccggatgtc tccttcataa
     7801 aaatgagcat ctggatgtac tgcttgtttg tgacctgtga gcaaattatc taccacagct
     7861 acttgatacc ccttttgaac tagctggtct acagcgtgcg aaccgatata accggctccg
     7921 cctagtacta aaattgtcat aaaaaacact cctttgatta gtaaaattgt gtttgttgat
     7981 tctatataat ttaaaaaacg aagtttactt ttatggtgaa aacaaacaaa gtaaaatttc
     8041 gtaaattcat atggtaaatt tataataaaa catttagtaa acattttcaa gggttttttg
     8101 caaaggttta caaacaaacg taaaactagc ctttttttct cttttgttcc ataatagata
     8161 taacaaataa taaatgaggt ggattcaatg aaaaaatttg tatctggaat attagtagga
     8221 agtctggcaa cagccgctgc cgttgctggt ttggttgctt ctgtgaaaaa aacagtgatc
     8281 gatccaattg acgaaaaaga agcaatgatc gaagaaaacc gtaaaaaagc aatgcgtaaa
     8341 cgcgtttctc gttaataatt atttaaaaat acgcatgaag actttctaaa aaacagataa
     8401 gtcatcatgc gtatttttat ttgtcagtca atataagttg tgctatttta tctgcctgtc
     8461 tcagattcca tggatctgta taaggtctag ctactgctgc agttagccaa tccacacctt
     8521 caacaggtat tccatagcaa taaaagtcag actggatttc ccctgaagca tcaatcacgc
     8581 gattcgtacc tcgctcaaca tctatagctt ctgaatgata acttcctgta ttatctgaaa
     8641 atgaaaaagg gcgaacaagt ttgttttcct tcaaattttt tatgacagga ttacttgaac
     8701 gagaaaagct tgtttgtggc aatcgagctt caatcaaata gcgactgctg atttctttat
     8761 cttgtagaga aataacatag cggttgtgct tttgctgaat atcaaatggc ggttcgatca
     8821 aatgaaaaat acccgcatct atcagtgctg ctaattcttt cgtccgaatg attggcggac
     8881 cgatcgttaa aaagctattt agatgagtaa accatcccca tagtatttct ttgtattcct
     8941 tagcagaaaa aacgtgccat tcaatagcct gccggattgg atcacgccag tcttttaatg
     9001 catcaaatgt tgaagcaaat gctcctgtgc aattgccttt ttccgcttct tttatctgcc
     9061 cttcaataaa tattcggcta gcttctgaaa agggctcatt ctgataggca agaggagttt
     9121 ctaaatacga ccaatcccat ctataaggga ttagtgctgg atgctttccg agacactcct
     9181 ctgaagagag ggagagaaaa tcatgctcaa aatttttctt tggaatcggc aagtgatatt
     9241 cttcgatgat tttcttgtaa taaaacaact caacgtcttt tttcagatag tcaaaaaatg
     9301 tttcgccagt caaaaatccc gactgatgcc attgctccag gttttctttt gttagtaacc
     9361 gtggccatgc cattgctccg ccttgctttt gatttcttcc tcgagggtaa taagggagcc
     9421 cccttcttga tccactgtat acaatcggtt ccttgcctga tggatgatag accagttttc
     9481 ccttttcgtt ctcgaagcgc cctcctcttg atactgtaaa caatccgaca taatcaaaaa
     9541 aacttaagcc tagacctctt aaaaagacat tttctttagg cggtatcttc gaaagatcta
     9601 catctgcagg attagaagga agctgataca gtaaaacatt tttctttgcg tagtctaccc
     9661 acactctttc ttcttctgtc tcatcatttt cccagtgacc gcttgctaaa acaagctgat
     9721 cgatagaata gctttgctga tctgtctgta aaagataacc atcttttctt ttgcttactt
     9781 tttttactaa agaataaaca aactgaatag aagctggaaa ttcttcttgc aactttgaga
     9841 aaaaccagcg ttgatagagt ccgtataaac atcgagtaga ttgctgatct ttttccagac
     9901 gattgatttc ttctataatt agttgcttat ttttggttac cgtctgttcg atataatctg
     9961 tagcaggtcc tttactccat tgaaacaagt tgggtccctg tgttaccaat cctccactgg
    10021 acaatgtttc atctgtaaaa agcgtcactt gttgagaaac agaattcatt aataactccg
    10081 gtggctgatt caaccgccaa actcgacctc caggaccatt gggatcgaaa agaaaaagtt
    10141 caagagaatg tctgtcctga ttattatgga gaatcctttc tgctacactt aatcctctag
    10201 gtccggcacc aatgatccct attttcattt gcatgcctcc atttcgataa attttttcaa
    10261 taaaacagca tggttctgat gttcattttt tgcaccataa acaaaagtaa tgactggatg
    10321 ttctttcata agttgactga gtttaaaaat agcttgcttc ttttcttctt cgaaaatcaa
    10381 ttcttgctgg tatttctttg caaatgaagc aaatcgttct ggtacatggt caaaagtttt
    10441 gcgtgcttca ttactaggtg caatttcttt caaccacaga tctaactgcg ctttttcttt
    10501 tgaaattcct cgtggccaga atctatccac gagtattcta tagccatcct ctttttcagc
    10561 atcaaggtaa acacgtttta atttgatcat agttgtttcc ttctttctac cttttcgctt
    10621 agcttatata tgtagataat agcacaaaat aaaaaaaatg aacggcacaa ctatccattg
    10681 cgccgttcat gtgatcttgg tcaaaatcta atgattgatt cggtttttaa agctgtcata
    10741 caatcatctg ttttatactt ttttactttt gatttttcca gaccatccgt catatccacc
    10801 cttaagtaaa taaatctctt gataacctgc tttacgtaat ttatttgctg tacggatgct
    10861 caaacttttc ttttgatcgt aaatatagac aggctggtct tttcgaatag atcctaatga
    10921 atctttcaaa acagtgtaag ggatgtttct tgcacctaaa atatgcccag catcaaacac
    10981 atctttttcg cgaacatcga ttacttgtgc ttttctcatt ccttctcgaa attcttcttc
    11041 tgtcaaagtc gttgctgaac gtttggccat tactcgtaga tagacttccc aaaggatgat
    11101 tgcaagcaca atcaatagca aaatgatatt aattacccat aaaaccatgt aatgcctccg
    11161 tttttttaag caaatttcaa ggctaatgag gcagcaccaa tgacaccagc ttcattacca
    11221 agctctgcta atttgatttt tgttgattct cttacttgcg ggaaagtaaa ttctttaaaa
    11281 tatttctcta cacggctacg taaaaattct cctgctgccg atactcctcc acctaacacg
    11341 atacttgacg gatttaatgt attccccaag tttccgcaag ctaaacctaa gtagaagcat
    11401 acgcgatcaa caaccatcaa tgcaaacgga tcgtcttctt gagccatttc aaagatatct
    11461 ttacttgtta cttcttctcc gttgtctagc attgctttca gttttgaatc ccctgcgtat
    11521 tcttctgcca agaaacgacc taggcgtacc acacctgtag cgctagatac agtttctaaa
    11581 catccgcgtt taccgcaagt acattcgaac ccttcaggat ccacagtgat atgtccgatt
    11641 tctcctccag ctccgctcac gccgtgaatc aaatttccgc cagcaacgat acctccgcca
    11701 acacctgttc ctagagtaac gaatacaacg tctggatcgt tttctccagc acctttccat
    11761 cgttcaccta aagcagcaac attcgcgtca ttatcgatag cgaatttgat tcctgttcct
    11821 gcctcgatca gttttttcac aaattgaact tctgtccagt ttaagttata cgcaccaata
    11881 accgttccag cttcgctgtc cacgcttcct ggggtaccca tgccgattcc gataaagtct
    11941 tcggctttca tattatataa attcaaacga tgattgattg attcaatgat ttcaggaacg
    12001 atatgcttac catcatccaa aatattggta tcgatgctcc atttttgctg aatctctcct
    12061 tctggtgtta aaattgcaaa ttttgctgtt gttccaccta aatcaatccc aataatcttc
    12121 ttgtccatta caaatttcct ttctttcggc tttcttcaat tcggtgctct ctttttaata
    12181 tgcgccacgc tgtcatgtat gtatcatgat caatcaaacg gctatcatac agattacgca
    12241 attcgatagt cattaattca atgtcataga tgcgtgcacc cacatagata aagatgccaa
    12301 attttttgaa cagctgctgt acatcatata agctctccat ctttaagcac ttccttcata
    12361 ttatacaagt aaaccatatt tttttaaacc cagtaaaata catattacaa aaagaaatac
    12421 aaaaactagt gtagaaagaa tcctttggtg tatcgaatag cttgtctgtt gtttcggtag
    12481 acccaaaaca ttccctaaca ctaatccgcc aattagccca ccgacatgtc cccaaacatc
    12541 tacagaggta tccagaagac caaaaacaaa tgtcaacaca ataaataaaa gaaaatgtct
    12601 gactagctgc tggatcgctg ggttatgttt aaaatgaaac cctaagataa acaacgcacc
    12661 gaacaaaccg aatatcgaag tacttgcacc accagacaga acattcgctt cgttaaaagc
    12721 aaagcttgct gtatttccca ttatcccgct gaacatataa atcaagaaaa aacgccaatg
    12781 gccatagatt gcctcgattt gctgccccat aaaatacagt atcagtgagt tcattacgaa
    12841 atgcatcagt ccaaaatgga tgaagattgg tgtcactaaa cgccaccatt cattgaagtg
    12901 aacaagataa ggaccataca ttccggcata ataagggatc tcaagtcgcg gaaataattc
    12961 catcatgagg aagaccgctg tctgtatccc taaaaaagca taggtccata acggtcgtct
    13021 taaccatgca cgcaatttta tttgctgttg ataattcatg aaaacctccc atttcatttt
    13081 agtcaataaa caattgttgg atcttctgat caaagctctc cggttgccat tgttcattca
    13141 attgttcacg aaaaacaagg ctacatgttt ttttatgaaa attatttaaa taccggtcgt
    13201 aataaccacc gccaaaaccg attcgataac cggctctatt gtagataata cctggtacaa
    13261 tgaggagatc gatcatctcc ggcaaataga gcttctctga ttgtggctca agaacaccaa
    13321 aactcgaacg tacaagaacg gactgttcat ccatttcata aaacgccatc tgacgtttcg
    13381 gcaaagtttt aggtacaact attttctttt gttctttttc tgctcgttgg ataaccggct
    13441 gtgtatccag ttcaaattca ttcgataaag tcgtccctat cacttttgct gacttccagt
    13501 actcgctggc gaatagctgt ttatagattc gctgttcttt ttcctttttc ttgccacttt
    13561 tggccagatt tttcagcttt tcgattcctt tccggcgtaa tcttactttc aattggtcca
    13621 aaaactcacc cttccttctc tcataaaatg gtataggaaa aaaagaaaaa tagcaatcga
    13681 actttcaaat aaatgcataa atagaataaa aagaagacct agaaatgatt ggccttcctt
    13741 ttttaatgaa tttcaactgt tcagcgcgtg tttttgtctg ataaaaagtg catacagaaa
    13801 atatggcgca ccaaaaaggg caatcaaaat tcctgtaggt acttccccac ttagtagaat
    13861 cactctagca accatatctg cactaagcag aaaaatggaa ccgaacaaac cgctcagaac
    13921 aaaggtccag ttattttctt tacgtacgac tagcttcgca gcatgaggag ctagtagtcc
    13981 tacaaaagat aaactacctg tcaccgctac actaccgctt gccaaagcaa cagctaacaa
    14041 caaaaggatt ttttgacttt tagccacgtt aaggcctaat ccttgcgcgc gttcttgacc
    14101 aaatgatagc aatacaatcc tctgtgcata aagtcctcct agcggaatta agataaccgc
    14161 ccatggaagc aatgcccaaa cataaggcca gctcgcaccc cagattgatc ccgctaacca
    14221 tgcattcaca aatccataat tttccttaga taattggatc gtgcatagca atgttaatgc
    14281 agaaaggccg gcattaacgg caataccgga caataagatt cgattcatac ccaaaaagcc
    14341 atttcgatca taggccgcaa gatagacaca gcaagcagct aaaacaccac ctagaaaggc
    14401 tacaactagc aatagaaacg gcagcgaata gtgcgaaaag aaacctaaat aaagcatcac
    14461 taaaaatcct gctccggcat taatgcccaa tatactagaa tctgccaatt catttcttgt
    14521 tactccttgc aagatataac cagaaacgcc aagacaagct cctgctaata aactgatcag
    14581 taatcgagga actcgaaatt ctctaacaat cagcgccaaa gaagatgatt ctttccctat
    14641 gaacgtggca aaaagctgat ccaggtaaat aaaaggcgta ccaatcatta aactacctat
    14701 agacaggatg acaagtacaa aaagcaagaa atagaacgtc caatatattt ttttcaccgt
    14761 tgttccctcc ttacttgtat cagtaaaaac ggaacgccaa tcaatgcaat gactaatcca
    14821 aaaggtgttt caaaaggggg attgatcatc ctcgctgtaa aatccgccaa cataaccaat
    14881 ccaccgccaa ctaaaaaaga gacaggtaga acataacgat agtccgttcc aaccattccg
    14941 cgaacaactg gcggaaccaa cagcccaata aatgaaacag gtccgactaa cgaaacggca
    15001 atggctgcta acactgcaac tagacagaaa acaatcaacc gcgttcgttt aggatgactt
    15061 ccaagagcta atgcatgtgt ttcactcaaa tgaatcaaag atattgcttt tcctaatgaa
    15121 aaagaaacca aaacagcaag tatatataaa ggaaacaata ctgctaattg tttccatgtg
    15181 atattggcag ctccgcctac aaaccaaaaa gcaagatcct gctgcagatt aaagaattgg
    15241 gtaagtgctt ggctgatagc agtaaaaaaa gaactaatag ctacgccagc taaaatcagc
    15301 tgtaaaggat tcatgcccat tttcgaaaac tgcaaaaaac caaatacgag caaagttaca
    15361 gcaaaagaac ctgccaatga cattagaaac acagaaaaat cagaagcttt aggccaaaaa
    15421 gcaaaactaa gggccattgc caacgaagca cccgcgttga ttcctagtaa gcctgaatct
    15481 gctaaaggat ttcttgtcac tccttgcatc aatgcaccgc tcaatgcaaa acaactccct
    15541 acaagaaatg ctcccgccac acgaggcaaa cgaatatttc gtatgatttg gtgactttgt
    15601 tttgatctat caaaatcaaa caacgcctgc caaaaatctg cttttcccac agtcgctgcg
    15661 ccatttgaaa gagcaacaaa aaaaataatc aaaagaacaa aacagaccaa aagcaggagt
    15721 ctatttttct tcatagtcct cataattgat cctcctgctc ttttggcaac aaatcatagg
    15781 ttagaaaaac tggtttattt gttcttggaa gcgtgacaat cgttgcatca atctcaaata
    15841 tttttttcat acactctttt gtgatcactt cttcaggtgt accttctgtg atcaacttac
    15901 cgtttttcat tgctaataaa taatctgaaa aacgtgaagc atgattaatg tcatgaatcg
    15961 acatcaagat cgttgtttgt ttcatttgat tgatttcagt caataactgt aggatctcta
    16021 attggtgtgc cggatctaaa aatgttgtcg gttcatccaa gatcaagata tctgtttcct
    16081 gagcaagcgc catagcgatc cagacacgct gggtttgtcc accagacagc gttgcgatat
    16141 cccgcatacg aaatccagct agacctgtag catccaacgc ccactcgatt gcttcatgat
    16201 cttgcgtgtc catgccactg aacagttttt gataagggta tcgtccgtaa gatactactt
    16261 cttctactgt catacctgta gggtgttcac tagtttgtgc taataatgca attttttttg
    16321 caagttcttt tgaactgtat gtagagatat cagagttatt gacaatgatc tttcctgatt
    16381 tcacaggtag tatacgggta aaacttttca ataaagtaga ttttccactt ccatttggcc
    16441 caatcaaact agtgattttc ccttcaggaa tcgtaacaga catgttttca atgatttttt
    16501 tgttttcgta gccggctgca atgtcagctg ctcttaatct cgtcatttca cccatccttt
    16561 cgctgaaaat cattctcaat tatgacgctg tttcaacatt tcgtcaagcg ctactttcat
    16621 atctatagcc aaatgaagcg gttgacagcg ttcgaaatat caggaataat aaccaatgag
    16681 aaagattctc aattatgtta ggaggaaaga aatgaaatta aaaacaaaag tattcacatt
    16741 atctagcata ttgctgctgg ctggagtact gagcgcttgc tccccctctt cagataaaga
    16801 aacagctaca actgccaatt cgacgacttc atccaatagt actcatacag tcacagatac
    16861 acttggacat aaagtagaga ttccaaacgc gcccaaacgg atcatcggca gttacttaga
    16921 agactatctg attgcactag gggaaaaacc tatcgcccag tggactgttg gcagtggttc
    16981 cattcaagat tatctgcaag atgatttaaa ggatgtccca acgatttctt atgaccttcc
    17041 ttatgagaaa gtgttaagct ttgagcctga tttgctgttg atttcttctt ccgctactgt
    17101 cgaaggcggg aaatacgaac aatatagcaa aatcgcgcca acttatgttg taaaaaacgg
    17161 aacagatgtc acatgggaag aacaactaaa agatgtcggc aaagctttgg caaaagaaaa
    17221 agaggcagaa aagatcattt ccgattatca aaaatccatc aagaaaactc gagaagaact
    17281 agcagataaa atcgagaaca agacagctgc agtgttgtgg gtgaccaaca actcagcctt
    17341 tatggtcagc aaaaatcggt caagtggaag aatcgtatac gacgatctgg aatttggtgt
    17401 tcctgatcta gtggaagagg tctccaaaaa agccacttct gactggtctg ctgtttcctc
    17461 tgaaaagcta gctgaattag atgctgacta catcatcctt gtgaacagtg acaaagatgc
    17521 tgccatgttc aatgaaccaa gctggaagaa tcttaaagca gtgacagaca atcatgtact
    17581 gcaattcgga cctgaatcta gttggctata taacggacct attgccagtc aggaaatggt
    17641 caatgatatc aaagaaaaac taaattgatt ttaactaaaa aaagcatctt cacgattagt
    17701 cgtgatatgc tttttttctt attaacaaac tagacgcata gattttattc ttcttttgaa
    17761 gcaaccctat tttttactct ttcccatttt tgaaaacgat gggcatatag attttcttga
    17821 tccgttatcc cctcatactc ctctataagg gcgaagtctg aaaaatcaat attcccaata
    17881 tacgtatcgc cttcaaacgt gctatcgatc aatgttcgcc agatccgacc agtgtaagga
    17941 agaagttctt gaaaaatccg actaccaccc gaaacataga tatcttctga gatcgtttga
    18001 ctatacgaca aaagttcatc gatcgaatgc attacttccg cattttcttt cgtgcgaaaa
    18061 tttggctgcg ttgtcaacac gatgatatgg cgataaggaa gtgaaagatc ccccattcct
    18121 tcataggtct ttcttcccat cactaaaatt cgatccattg tatgttcgcg aaagaaacgc
    18181 atatcatttg gcaatcgcca tggtaacaaa ccatttttgc cgatcagacc atttttatct
    18241 tgtgcccaca tggaaataaa catattatcc gctccttatg attttagatg ttttgagata
    18301 aaaaaagtct caattctttg accagcaagg aattgagaac tttaaaaaca ttattttgtt
    18361 tcacggtgca aagtaacttt gcgttcgcgt gggcaatatt tttgtttttc caaacgatca
    18421 ggattgttac gtttgttttt gcttgttaga tagttacgtt ctttacaaga agtacactct
    18481 aaagtgatgt ttacgcgcat gtttttccct cccattttta caagaatcct ctaagatgac
    18541 tctcagactt gattatctta ccatgatttt ttctagattg ctagtgtttt tcacgatttt
    18601 gttaagtaaa actacttgac gataaataca acggttttac ttctcaaaca aaatcttttt
    18661 ctttttgtat aaataccctt acacttgttt atatagatta tgttttttaa taaaggggga
    18721 tactaatatg ccatggaaca tgaaggactt tcctgcatca atgaaaaact tagataaatt
    18781 gacaagaaaa aaagcaatcg acatcgcaaa tgcattatta gatgaagggt accctgataa
    18841 ccgtgcgatc ccaattgcca ttgatcaagc aaaaaaatgg tatgaagatg ctagtgaatc
    18901 agaaaaacga actttcgaaa aagaaaaaaa tccaagcaag acggatgaac acgatacgaa
    18961 tcctcgtgct ggaaaactgc ttgattcaga tgtgatcgta gaatatgagg aagaacaatg
    19021 gatcgtgaaa tctaaagggg caaaaaaggc aagcaaccat tttgatacaa aaaaagaagc
    19081 aatcgaaaaa ggaaagcaag tagcacaaaa caaagaatca actttgttca tttataaaaa
    19141 agatgggaca aaagaaaaag aaatcgatta ttgaacatat gtaaaggggt tgtgacgaaa
    19201 atcgtgtcac aaccccctta tgttcgaaac aatggtgttc ctctgccaac tccgaaccat
    19261 aagtcataat atctataaaa cgggaagagc tgttttttga aattgtttct tatcactcag
    19321 tgttaaacgg taggagaaaa cctctttttt attgatattt gattttcatc aaacagtcac
    19381 atagtcgatt gcttctgctt gcggaatcgt ttcatctaca aagtagactt tataccatgt
    19441 caagaaactg aagattgtcc agatttttct ttgctcttct ttacgtcctt cgtgatggtc
    19501 atctagcaac ttcatgattt tttcttgatc aaaaaattct tttgcaaaat ctgcttcgaa
    19561 caatgctttg acttgttcgt agccgtgttc ttctttcaac caagctttga ttggcacagg
    19621 gaatcctaat ttcacacgat tcgaccattt ttccggaaga tgtttgttcg cagcttgtct
    19681 gaaaatatct tttgtgttgt tttgattcaa taaaaactta cttggtattt gttgagccaa
    19741 tttcatgact tcgatatcca ataaaggtac tcggacttcc aaagaacttg ccatagaaag
    19801 tttatctgcc tttaacaaga tatcttttgg catccattga tgaagatcga catattgcat
    19861 cttattgact tcatctttga ttccttctgt tttctcgtaa tgaacagtca tgatttcatc
    19921 cacagatggt gctgtttgat attttggtgt taacacttct gatgcttctg attcttcgaa
    19981 cactcgagca tgaccgataa aatattcttt tgcaggagca agtgattcat ataaatggat
    20041 ccgtccatgg aaatttttca tttttccgat tttacgtcct aaattatagc gtgttccttt
    20101 tggtaatttt ttcaatcctt gagcaatcac acggatgaat tttgaattcg tatggaatcc
    20161 atacgtttgg tatcccgcaa acagttcatc cgccccttct ccagattgga ctacccgcac
    20221 actttgtgaa gcaagatttg ctaaaaagta caaaggtacg caagaaggat ttgaatcagg
    20281 ttcatctaag tgatactgga tcaaagggaa tgctttgaac gacatgtctc cgtcgatcac
    20341 tgctgctgta ttatctaagt ccaatagttc ggttagtttt ctggcttcaa tcgcttcatt
    20401 ataggtttta tcatcaaacc cgattgagaa agaatgatct ggtttcaata cagaggttac
    20461 ataactggaa tcaaccccgc tggataagaa agaaccaact tctacatcac tgaccgtatg
    20521 tgcttcaata gaagcttgaa cggtttcgtc gattttttcg atccattctt gtcgggaatg
    20581 cgtttctttt gtttcaaaat ctgcatccca atattgctga atgtctattt ttccatcttt
    20641 atacgtataa taatggcctt caggcaaacg atagacatct ttgaagaatg tttcgccgtt
    20701 taatggagaa tattggaaag tcatataagg tttcaacgct tctttgttca attctttgtt
    20761 aaaatcagga tgaggcagaa aacttttgat ttctgaacca aacataaatg ttccgttcat
    20821 ttctgcataa taatatggtt tgatcccaaa gtggtctctt gcaccgaata actcattctt
    20881 ttcattatcc caaatagcaa aagcaaacat tccgcggatc ttttgcaata attctgttcc
    20941 ccattcttcg taaccatgca aaaggacttc tgtatctgca tgtgtttgaa aaacgtggcc
    21001 agctgcaatc aattcttctc tcaaaggctg gtaattatag atttcgccat taaaaataat
    21061 gatctttgtc cgatcttcat tgtaaatagg ctgagtaccg ccctctaagt caataatact
    21121 taatcttctg aatcctaaag caacatgttt atcgatatat tctcctgaac tattaggtcc
    21181 acggtgaacg attcgatcca tcattgtatt aataattgtt tttttgttgt ccttgtcgtt
    21241 aacaaaacct acaataccgc acatttaact ttcacatcct aatataaaat tactgtttat
    21301 ttcattcata tgcatcttat catagaataa atagcggacg aatattttct ctcttacaat
    21361 ttcgtcacgt gaaaacaaaa gatgaaagtt tctgttttta cagaaaataa agtcccaata
    21421 tctaatttac catgttttct tttttgaggc taccttattc tcttcgtgtt aaaaaaatat
    21481 tagtggatgc tatttccaaa aaaaccagca aaaaaagaca cgacctaaag atcgtgtcta
    21541 attatgactg tatcagaaaa tatgatacca aacggatcta ttcattaatt aattgacata
    21601 gtttatctgt tgctctttta tgactggata actgaccaat tcatgacgat ccaagtcttc
    21661 tttattcata tttacagcag taatttgact gtcttcatac gtacgataat aataaatccc
    21721 tttatcaacg ttacagcaag aagaataaat cgtatattcg tattttcttt ctccagtatc
    21781 gcatactcct ttttgttgct cgactgagcc tagtatatga aaaaattgac tgatactttc
    21841 agattctgaa tcacctgatg cagcattcat tttagtaaat gtggctttta caaatcgaga
    21901 aacagaagag agatctccag gtaagcccaa tcctcccatc ccacgactat aaacattcaa
    21961 gctgatctgg tttgaaaaat gattttctgg tgttccattt gatagcgagc gataattgtt
    22021 cagattaaat aattgataat caaatggcgg attatttgtc aacacaccga caggattatc
    22081 atataaatga agtccatctt tcatactttc aattactatc gatttttctt tatcagctaa
    22141 taaccagtgt aaaggtgaca agggtagttt ttcactaaaa tcgatattga ctagattgat
    22201 agtagccaat aattctttag cttcgtctat ggttgagcat tgccctagta tccatggaat
    22261 aaactcaaat ggtgcaacgt tatcttttcc ttcttgtaat tctttataat cagcattgcc
    22321 aggaaaattc agtcctgcca tactcaaccc tttttcattt gtagcctcat aatagagtgg
    22381 atagttggat accccagctg ctattcctat cattgcataa tgtttatcta aattttttac
    22441 ctttctaaaa tcgaaacgat aatttcttgg agtaatagtg accacttcat tataagacat
    22501 ctcataatca aaattccttc caaaataatg gtctttcgtt gcataagtga ttgcggtaca
    22561 catcgtttcc cgtcctaaaa caaatcgttt ttacactttt atcttacatc tagtattttt
    22621 tttatcaaaa aaaggccaaa gaagattgat ttactagcat ttataaaaaa tagtactcag
    22681 ggggaatcaa aaaatattgt aggttaaaag tacaacaata aggggctgtg acaaaagtct
    22741 tgtcacagcc ccttattccg aacaaacggt gttcaaaagc ttgcatctgc ggtaataagc
    22801 ccaatcaaac gaaaaaatag gaaaagctat ttttgtttgg ccgttcttat tacttgatgc
    22861 aggacagctt cttcacaacc tctaatcgtt gatataagga aggtacagga tttgaacctg
    22921 cgcgccggta ttagccggtt cgccggattt cgagtccggt gcattaccac tctgccaacc
    22981 ttccgtaagt actattttta aacttttttc acgaaatgtc aagcctattt ctaatagata
    23041 aataacagaa atcgcttttt ttagcaaaaa agtccattga cagtttgcag ccaacggact
    23101 taccgatcaa attcatactg atagaacact atctgattat ttcaggatta tctaatgcta
    23161 aaatcgagtc aattgtccgt ttgatcagtg caatgatttg ttcttctgtt ggatgcatga
    23221 tgtttgatga catcaatgac gctaagccag tcactgctac ccatgtacca gtatgcagag
    23281 catcgacata ttcatccgat aattgattgt atctttcatc ttctttaact atttcacgga
    23341 aataattgta tgaaaaatca tgcattttct ttccgtcccc atgttcatca atgtacaatg
    23401 ccatgtaaag actatgatgc ttttttgcaa agtagatata gttcaaaccg agatcaatga
    23461 ttttatcacc agtacgttca atagggaaaa catcttcttt tagttgttca aagatagaat
    23521 ccagcaacgt attttttaaa tcttccatgt ttttgaattc cagataaatc ggctgtgtcg
    23581 aaatccccat ctttttagca atatttctcg cagtaaatcc tttaaaccct tcctttgcaa
    23641 caacatcata agcagctttt agaatttgat ccttggtata gacttttctt ctcattaaaa
    23701 ctcccccact tctttactgc agtatatgtt gttttattgt accctatttt tagcattttt
    23761 tgcaaacatt ttactcaaaa cgttatattt taaatttttt ttcagtcttc tttaactttt
    23821 ttttgcaaaa ttaaaaaaat ttggttaaat tcaatgggtt cccttacatt tttagttttg
    23881 acctaaatga tagttgtcca aatctttcat ttcaagttat agttaaagaa aatgaaaaag
    23941 aaggtgtgta atggaaaacg aaactgacgt tatttatatt catcctcaaa aacgaatcgt
    24001 ttcacagaaa agaaagtatt tttatcttgg ttttacaggt gtttttttct ttttattggc
    24061 ttgctttcta atactcctac tgataattgg agtggattgc taactattct tacctcgcca
    24121 agcaatcttt tgacagatta ttttgcttta ggcggtttcg gaagcgcatt cataaatgta
    24181 gggattttga ccttactttc tgtgctttta gcttatcggc acaaggtgat tttaaacggt
    24241 cccttatttg cttcgattct aacagttacc ggtttctctt tttttggcaa aaacctttat
    24301 aattctatct caatcatttt aggtgtgtat ctatacgctg tatttgtcaa taaacctttt
    24361 tctcagtaca tcatgatcgg actgtttggt agcgcattat caccggtcgt tagttatatc
    24421 acttttggta tgcgttttcc tttactgata ggtattttat tggggaattt agctggcata
    24481 gcaattggtc tacttcttcc gcccttagct gctcaaactt tagttttcca tcgtggattc
    24541 acactttata atattggatt cacctctggg ttgattgcga tgacttttac tgctgttttg
    24601 aggttattca gctattcaat cgtcgaaaat acattggttt tcaatgaata tcactttcct
    24661 ctcatttgga ttatttttgg ctttttttcg ctgacagtcg gaattggttt ctattataat
    24721 tcctttcggc ttttggggat tcgagaaatt ttcgattcat ctggaaaatt gacaactgat
    24781 ttcattgcta attctggtat tggtgctact ttgatcaaca taggcttagt tggtctgatg
    24841 ctgtcttctt atgttttgct ggttggcggt cagttaaatg gacctgtcat cggtgctatt
    24901 ttatctgcgg tgggtttcag tgcttttggt tgtcatttaa aaaacagttt tccgatacta
    24961 gtcggaatat ttattgcttc tttgtttgga acttttcatg agatcaccag tactggcatg
    25021 cttgttgcag ctgtgtttgg gacaggtctc gcgcccataa gcggttttta cggcagtttt
    25081 tacggtgtaa tagctggtgt actacatatt gctcttgtcc ataacgtcag cactttgcac
    25141 ggaggactaa atctatataa cagtggtttt tcaactggtt tcgttgcagg tatccttgta
    25201 ccgatactag ataactttac cgctgtcaga aaggaaaaaa agacacttgg aaaaagaatt
    25261 atcaaaaaga atcatcgatg agcttcttac ttatttatat tcccatgaaa taactgaaat
    25321 acgtattgga gtagaatttg ctgaggaagg gcttttcata gagatacagg gtacggcaga
    25381 aactcagcca gaagatttag atgtacttgc tgatttgctg aacaatcctc gggaccctag
    25441 tatggaaatc tattatcaag aactattagg taatccccga catgatcggg aagattatca
    25501 tctgttaggt agtttgattg atgacgtgga aatcatgtat gcccagccga ttatcaatat
    25561 taagatcttt cgacgtgctt ctcattccta ttattaaccc tattttctat ttataaaaga
    25621 ctgaatcaaa aaagcagctc ctgaaagttc gattaaaatc tactttcagg agctgttcaa
    25681 gcttgacatt attgattttc caatccttca tacacttcat ctgttacagg ttctaaaaac
    25741 tctgaattac cagcagtgat cgccaaatgt tcaaaccaac tgtcttttgt cgcaccatgc
    25801 caatgtttaa tccctttgtg cgttacgacg acatctccag ccattaatcg tcttgctggc
    25861 tttccttctt cctgatacca gccttctcct ccggtcacaa gtaagatttg atagccgtct
    25921 ttatggacat gccagtgatt gcgacaacct ggttcaaaag ttacattacc tacaccaaca
    25981 gaaacttcgg gatcattcac taacatattc agatagcttt acccggtaaa tacttgagcg
    26041 taagcttcgt ttttttcacc tgctggaaaa atcacgccat tgtgtatttc ttcgtgtttt
    26101 gtcgtcattt acgcctcttt cttatcttcg ctattttctt ctaaatagat ttcttttgct
    26161 aaactaaaag ctgaccaagc ttttggccat cctacataaa aagctaaatg ggtaatgatt
    26221 tctgctattt cttcactagt aatgccattt tgcttgccaa tcttcagatg agctggcaat
    26281 tgttcaaaat ttcctcctga aattaatgca gatatggtga tgatactacg ctgatgagca
    26341 gataattctt ctctggacca tacttgtcca aataaaacat catcattcaa ttctgcaaat
    26401 tttggtgcaa aatctcctaa ttgatctcgt cctgcggttt gtttttctgc catttctctt
    26461 attctccctt cacgactgtt aggtgattca actatggttc taaggcaact ttattttcta
    26521 ttgtttcttc gcatttcatt ttaaatgtag tctttcagcc tgtccaatgc ttagtttatt
    26581 cagtcgatat gctttttaag catagttgct aacgcttttt tt
//
LOCUS       DAXLPY010000036        24842 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.036, whole genome shotgun sequence.
ACCESSION   DAXLPY010000036 DAXLPY010000000
VERSION     DAXLPY010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.036"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(301..864)
                     /locus_tag="ACF3UF_001606"
     CDS             complement(301..864)
                     /locus_tag="ACF3UF_001606"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFD3671720.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLIDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(879..1922)
                     /locus_tag="ACF3UF_001607"
     CDS             complement(879..1922)
                     /locus_tag="ACF3UF_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671721.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(2055..2459)
                     /locus_tag="ACF3UF_001608"
     CDS             complement(2055..2459)
                     /locus_tag="ACF3UF_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFD3671722.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(2659..2907)
                     /locus_tag="ACF3UF_001609"
     CDS             complement(2659..2907)
                     /locus_tag="ACF3UF_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005225422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3671723.1"
                     /translation="MHWLWVLIVGAIIGLIAGAITNKGGSMGWIANIVAGLVGSAIGQ
                     ALLGSWGPQLAGMALIPSIIGAIIVVAVVSFFLGRSRG"
     gene            complement(3542..4489)
                     /locus_tag="ACF3UF_001610"
     CDS             complement(3542..4489)
                     /locus_tag="ACF3UF_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005470715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3671724.1"
                     /translation="MYSYYKIEKNQIRESSEEDYNWLVVKHGNEEEKKELLTLFDLPE
                     DIFIGSDEPEEVSRLEHLRDTKLNNPFLYTLIDLSSNHQERIEKRLEPVTFILSKGLM
                     ITYVSRESNLVERLIEKHGSELRHFEDIIAFATLMIYTHYINGLKEIKKQIDQLDAAA
                     RKTTENNELFNLADTERDMVYLDHTLKDQNLTVNHLMERKEFLDKLDNESLVYDIKLR
                     QKFANKLVTIYRDLLETIGGLFSDMMDNNLNHLMKYLDSAALVVAVPSLIAGLWRINT
                     GGLPGKDNTIGTILVFGLAVLVGILTAVYLSKKDFSKTK"
     gene            4681..5508
                     /locus_tag="ACF3UF_001611"
     CDS             4681..5508
                     /locus_tag="ACF3UF_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFD3671725.1"
                     /translation="MFLHQKELQFEAKPDKPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMKKDPAIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDLLSVLLARDSYHQNLWAQAVKELEEKEGTILVPSTFPRNEERLDIAY
                     DFYNFSEGDQSKEGSWGKGKALDGEGEYQWLSTPKVEGKAPKLDPVTPKMYGTPPEK"
     gene            5650..6489
                     /locus_tag="ACF3UF_001612"
     CDS             5650..6489
                     /locus_tag="ACF3UF_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFD3671726.1"
                     /translation="MKAPLLTLNDGNMRPAVGIGTYQIRGGEGLSQLQAAIADGYRLI
                     DSSTNYDNEGIVGKAIRRSGVPRSEFYITSKLPGKYHGYDDALTSIQESLARMGLDYF
                     DAFLIHWPLPKRGKYIEAWQALVTAQKLGLIRSIGVSNFEPEHLDAIIEATGVTPAIN
                     QIEIHPYWVQEQMVAENRKRGIITEAWSPLGRGSAALKESIITDLANKYQKSAGQVIL
                     RWHVDRGILPLPKSRNLSHQRENLAIFDFELTEEEINAINRLNKEDGRIEGQDPNEYE
                     EFE"
     gene            complement(6741..7478)
                     /locus_tag="ACF3UF_001613"
     CDS             complement(6741..7478)
                     /locus_tag="ACF3UF_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008379144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar isomerase domain-containing protein"
                     /protein_id="HFD3671727.1"
                     /translation="MYQYVDKIHALLETVEKKEQHAIDEAIRLLTTANLEKHSIYIFG
                     ASHAGILAEEMYYRAGGMMTINAIFGRELMLDRSPITFTSKMERLEGYGTALAEIQPF
                     KEGDVLILHSVSGRNPVIIDLALAAKEKGVKIIALTNKTYSQSVTSRHSSGLRLFEVA
                     DLVIDNHGEIGDAGCQIKGMDQKVGPTSTVIGATILNTIIVEVCQQLKQAGIDYPPIF
                     YSANMDGGDELNQSLFEQYKEAIHYQL"
     gene            complement(7480..8730)
                     /locus_tag="ACF3UF_001614"
     CDS             complement(7480..8730)
                     /locus_tag="ACF3UF_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFD3671728.1"
                     /translation="MSFVTDHILKNPPVLLGLIAMIGLIVQRKPFAEVVKGSLTAAFG
                     MVALTAGVNMLTGTIAPINTAVQTQLGVQVADGLSDVTFTAEYGGTVGLAMFFGLILH
                     LLIARFTPVKTIFLTGHMLWWFPFVIVAGGVEGGMSGIPLLILGAVLSACYWSFMPWI
                     MRKYVWDATGDDSFLIGHPTGILSMVSGFVAKRVGNKEKSTEDLKVPENLSFFREISI
                     TGALVMFLMNIVVGIIAPVLVPEGGNLVMFAVQAGLNFGAGLLIMLYGVRLLINQIIP
                     AFQGIAEKVVPGAKPAFDVPILFNYRPNAVIIGFIVAMITSTILVIIVNTTNVFGILI
                     VPLVITSFFECGGAAVIGEGQGGLRGAVIGTIAASFVMVLLVGVSAVLFSTTIQNWIL
                     IFGGNDISLWGIIGRGLGSLFGGI"
     gene            complement(8733..9014)
                     /locus_tag="ACF3UF_001615"
     CDS             complement(8733..9014)
                     /locus_tag="ACF3UF_001615"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3671729.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIDKVIKELGLKATAENTDLSTAKA
                     TPADVYFTSHELLNDLQASVKAPVYPIKKYMDVAEVKMQMEKFLAEREG"
     gene            complement(9027..9458)
                     /locus_tag="ACF3UF_001616"
     CDS             complement(9027..9458)
                     /locus_tag="ACF3UF_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3671730.1"
                     /translation="MINLKKLLPEDHIETTNQILTWQEAVQLASQPLLNEKAIDQQYV
                     ANMIHSVEENGPYMVLADYFALMHARPGEGVFHQGMSLLVTKNEIDLAGKSVRIFLVL
                     AAKDNQSHLESLQEIMEVFMDQEKYQLILNGDKEQICQLFQ"
     gene            complement(9455..11092)
                     /locus_tag="ACF3UF_001617"
     CDS             complement(9455..11092)
                     /locus_tag="ACF3UF_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3671731.1"
                     /translation="MKNNYSLIEDRRMQIFKRLINGEHLSYQQLSDEYYVSRSSIAKD
                     IAYLKTLFVKENLLLRFDNSGTYFQGSESQIQRMLKRFILLTVEHGENLSVLTNVSLF
                     EKINAAFRHSITEKQMEIPESYIQSIVVSILLIVERSNQANQLDIEEKRQFGKLFLEF
                     DKYPLIYELLKEIEEQEIYHFSSKEVQYLTYLIVGSGLRFFMKNESIPFSFRGKVRNL
                     IQKVSEGIQIDLTQDSRLEEDLTIHLYQLFLRIEAQTTVVNPLLDEIKQHYPALYGVV
                     WFSLDDFLKAYHIGISEDEIGFVSIHFQAAVERMRQLNKIVFVCPNGVGTSSFISAKI
                     RRILPNVDSIETASVAKLKEMDISAIDFIISTIDLPDVSKPVVRISPMVTNRDMKRIM
                     NHYIDLIIDNEPIADKVKILQDTRMLIAPKIYFERFETKEQALDFLISQNDFSSENQR
                     TDFQRSVLEREALQSTYLDNGFAIPHGNPEFVSKTTFSVLILDRPVDWGNQKVDIIVL
                     LMIREDEAQEVEPVMKLIMQGIEDKEWFISKMLEVKS"
     gene            11306..12199
                     /locus_tag="ACF3UF_001618"
     CDS             11306..12199
                     /locus_tag="ACF3UF_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HFD3671732.1"
                     /translation="MKWRGGRQSSNVEDRSGRSAGSGGKIMVGGGIGTIVIAVLFFLF
                     SGGDLNSVTDILGGGQAANYQTENVASDEYTEEKEFSAVVFGHLEDYWNGVFEAEQTT
                     YQDPKLVLFTGSVQSACGNATSQVGPFYCPADQNVYLDLSFATELSQKYGASGDFAMA
                     YVIAHEVGHHVQNELGITQQLDKIRQQVSEKEYNQYSVRLELQADYLAGTFAKYLQGK
                     TYNGQPILEAGDIEEAITAANAIGDDTLQKEYQGYVVPDSFTHGTSKQRVEWFNRGFK
                     YGDLEHGDTFNEKNLDLVYGS"
     gene            12541..12622
                     /locus_tag="ACF3UF_001619"
     tRNA            12541..12622
                     /locus_tag="ACF3UF_001619"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12574..12576,aa:Leu,seq:cag)
     gene            12777..13280
                     /locus_tag="ACF3UF_001620"
     CDS             12777..13280
                     /locus_tag="ACF3UF_001620"
                     /inference="COORDINATES: protein motif:HMM:NF024954.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3671733.1"
                     /translation="METERQIRELEKAMNTTDNRRLYERFLAVKLVLEGHTRKEAGHT
                     IGRDEHTVSHYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELVQIVAYHTPEEVGFK
                     SRANWTLAIVCDLILREWSYGYTQKGVADLHNFPPRYYEYPGGVIACVTAYANLQHRS
                     KWLSSKK"
     gene            complement(13493..14248)
                     /locus_tag="ACF3UF_001621"
     CDS             complement(13493..14248)
                     /locus_tag="ACF3UF_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3671734.1"
                     /translation="MDFEQNVRLNFDLLSDNEKDMVFFIRTHKAQVVHMSIVELGEQL
                     LSSKSSVLRLAKKLGFRGYSEMKYSLEQSIVQSVIPPTDLIALLKDEINRTFQLADQT
                     NFQPILEQLKAAKTVVVYATGFTQNNFSKDFVNDLILSGRPAMLISGETNFEMLSHTL
                     TKDDFVIVTSLSGETPSIKSTIKNLNMNRIPLCGVTELGKNFLSEHSDFLLYYETREL
                     PSNLIEGSRSMIGLNILLSILSRKYREFILFDE"
     gene            complement(14355..16025)
                     /locus_tag="ACF3UF_001622"
     CDS             complement(14355..16025)
                     /locus_tag="ACF3UF_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFD3671735.1"
                     /translation="MNEWWKSSVVYQVYPQSFKDSNNDGIGDLMGIVEKLPYLAKLGV
                     DVIWLTPIFDSPLIDNGYDIRDYEKISENYGTLEDFKRLLEQAHQLNIRVILDLVVNH
                     TSNQHAWFIESQKNKENPYSDYYIWKDPKEDGSAPTNWGSTFGGSAWEYVESRKQYYL
                     HCFAKEQPDLNWENPKVRQSIYKMMKKWFDLGIDGFRMDVISLISKHPDYPDAPNSMP
                     YTKSYYVGASNGPRVHEFLQEMNREVLSKYDSLTVGETPNTNSRQAQLYTFPERKELN
                     MVFHFDHMHLDYGKYGKFSDVRFKLSDLRATLSEWQEALSDGWNSLYWSNHDQPRAVT
                     RFGDENEYRIESSKMLGTLLHMMKGTPFIFQGEEIGMKNVPFSSIDEYQDIETNYFYK
                     KMKEEGESDEYIKRAIYLKSRDNARTPMPWDHSKGYGFSNSDPWISFSPDNQQINVED
                     ALKNPNSVFYHYQKLISLRKNYPIIQHGTYKLINENDSAVFGYIREYKNELLVVICSF
                     SKESVPYELPKSLQGRKGVLLLSNYEQSPSELEDKFILRPYEALVYHI"
     gene            complement(16029..16448)
                     /locus_tag="ACF3UF_001623"
     CDS             complement(16029..16448)
                     /locus_tag="ACF3UF_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3671736.1"
                     /translation="MKKIIFASHHNLAVGLKDTVQYILPNVGEITAIAGYIDNSPIEE
                     KINEVMVRDNEDTDILIFTDMLGGSVNQAFIKYINQPNVYLITGMNLPVVLTILLNTL
                     NKRLTDNHIREAIQEAQDQLVYVNDYLKNIVVDEEDE"
     gene            complement(16461..17270)
                     /locus_tag="ACF3UF_001624"
     CDS             complement(16461..17270)
                     /locus_tag="ACF3UF_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3671737.1"
                     /translation="MNNEGNKLSKKDIRRAAFRYMFMACNIFNYENQQGPAVVYGLEK
                     ALRKIYPNDEDYRASLNNHFKYFNTTTWMANLLLGASLAMEEKDGVSSLDAVQSFKTG
                     MMGPLAGVGDTLVWVLYPTIMGSIAAYMGLEGNPTGAIIWLCLNLFFLFFRFKLFSIG
                     YTSGLKLVTALGSKLSIFTESASIMGLTVVGALIPSVVKMNVAVVFQSGKVKLPIQTE
                     ILDKIMPALLPAVLTIIVYKLIASKKMTVIQIIFSVIIFALILSFFGILKV"
     gene            complement(17263..18063)
                     /locus_tag="ACF3UF_001625"
     CDS             complement(17263..18063)
                     /locus_tag="ACF3UF_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3671738.1"
                     /translation="MEIIQGILIIILAVWVVLDQQGLVITTWFPIMIALFAGLIMGDM
                     TTAMVIGGTFQLMALGVANIGGSSVPNWGLAALVGIYVAIRTTNNIEEAKAVALAVGV
                     PVGMLGIQLDVLAKILNTYVTHAAQKAANKMDFKKMNQILWLGPVIFGLSTAIPTALC
                     VVFGDRIVRLILDFVPKWFTDGLSIAGSMLPVVGIALLLQVMPVKKYMTMLLIGFVLS
                     AYLNMPILGISIVGFALAYYFFTTEIKKAETASPVAANIVDEGDDFDE"
     gene            complement(18078..18554)
                     /locus_tag="ACF3UF_001626"
     CDS             complement(18078..18554)
                     /locus_tag="ACF3UF_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFD3671739.1"
                     /translation="MGLVLARIDQRLIHGIVVTQWAGATKAKRLMVVDDQVSKDDTQK
                     AAMRMSKPAGTGMSIIDTDTAIINFKLGKYDSHNVLMIVKEPSTLVKLAENGIDIPKV
                     NIGIMFDGEGKQTVKKMVSVDEQEIADLKKLEAMGIPVTFHFVPSDPEEPLDVRIK"
     gene            complement(18949..19428)
                     /gene="rlmH"
                     /locus_tag="ACF3UF_001627"
     CDS             complement(18949..19428)
                     /gene="rlmH"
                     /locus_tag="ACF3UF_001627"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFD3671740.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAHISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            19857..21143
                     /locus_tag="ACF3UF_001628"
     CDS             19857..21143
                     /locus_tag="ACF3UF_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFD3671741.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTTSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSGF
                     GGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKDG
                     TKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYANS
                     VTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKI
                     ASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQE
                     QILKIPSSVTNGVIVTNVQTATPAEKAGLKKYDVITKIDDKEVSSGVELQSALYKKKV
                     GDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(21318..21923)
                     /gene="ytpR"
                     /locus_tag="ACF3UF_001629"
     CDS             complement(21318..21923)
                     /gene="ytpR"
                     /locus_tag="ACF3UF_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFD3671742.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(22128..22592)
                     /locus_tag="ACF3UF_001630"
     CDS             complement(22128..22592)
                     /locus_tag="ACF3UF_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3671743.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(22614..22934)
                     /locus_tag="ACF3UF_001631"
     CDS             complement(22614..22934)
                     /locus_tag="ACF3UF_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFD3671744.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(23077..24156)
                     /gene="pepA"
                     /locus_tag="ACF3UF_001632"
     CDS             complement(23077..24156)
                     /gene="pepA"
                     /locus_tag="ACF3UF_001632"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFD3671745.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            24356..24706
                     /locus_tag="ACF3UF_001633"
     CDS             24356..24706
                     /locus_tag="ACF3UF_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFD3671746.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
BASE COUNT         7457 a         5210 c         4420 g         7755 t
ORIGIN      
        1 aatcatttgt ttaaaatttt cttcatatcg ggtcataaaa attcatcctc tcgtagataa
       61 gtttaattta ttcttgtctc tacgaaaagc tgtctaagat ttgatactaa caccaaactt
      121 cataaagtaa atcttttata catttccact tctagatggt cattcatgtt agaagaatca
      181 aactattttt ttactgtcgt aataatatta aaacactaga acaaatcaat taaattccat
      241 aaaatataaa taatagacct agcatcatct ggtataaaat ggatgctagg tccgttatat
      301 ttactcaaaa ttgattctac gaatagatct tcttatcatt tctattttag tagtcatgcg
      361 ttgttgttct tctaaaggtg gtaatggtat aagtagttta gataaatttg taccatttac
      421 atttggttgc ccagttccgt aagaaatttt ttctaataac ttccaatata atggcgagtc
      481 taagaagcag tctacatatt ctgataataa tttctcaact aacctaattc gaatcaagta
      541 agaagcaaaa acagattcct cacttatttc cttaaccaag aaactttttc ccatagttcc
      601 tcctgtcctt gctatcaaaa tgtcattttc ttctaatctt aaatcaatta gtttagaatt
      661 actaatatca cagtaaggca cactggacca atttacacgt ccctcttgta tatctgtgat
      721 tctcaaaaac ttaacattgc cttgtttttt cgccgaatct gtatagccat attgaatctt
      781 agtagaaata cttcctaaat aaacccatag tcgaacatcg ctagatgatt tttcttgtcg
      841 ttctttatga acaacagtga tcatcttgag ttgtccgact attttttagt tgcagcaatc
      901 tttttgggac gcttatttgc atgaagcaac gttgctaagt ctagtaataa aacattggct
      961 aacacaggat tggctttctc gcgatacgct gcggcgccac tttcaaacaa tactgctaga
     1021 cgatcttcta caacaacgat ttgttccaaa tacggtggaa atttgattcg ttttaggatc
     1081 cggctaggag agtcccgctc ggacactaag agttccgagg tataaggacc ataagaacga
     1141 ctggctaaga gataatggcc ataaaaagcc acaccttgaa tcttatcaga tgtttttctg
     1201 ctcattgtca cggttggttg gattttgtct ttgcggcgaa ttgctgtttt catttcagct
     1261 atcgtcggca atagatagaa agtcaactgt ccttcacctt ttagtgtgaa gttgccagat
     1321 accagttgat cattgttttg agtcaaatac gatgcttgtg gaatctctga gagatcagtt
     1381 gtcagccaat aagcgattgg ctgtcccgtc tcttcagatg tatctgctaa gatatcgatc
     1441 aaacgtaaag cggctactcg tccagtagca gatcctgtga ttgtcaacca taaaagttcc
     1501 cgttttgtat catatactaa gccccctaca tgtggccgtt taggtaaaat cagcagtttg
     1561 atcggctgtc ctgtttctct atccagtaca tgaataatag aatgatgctg atggtcatag
     1621 cagtaggcag aaataaacac aaaatcttga gaaaaagcca acccttgcgg cgtcatccat
     1681 tgacaaacct cattttcgcc ggtttccggc accaccattc ttgtttctgt taatccagga
     1741 atgttatatt gttttgcttc agccttttcc caagctgctt gaacaatagg ataccgtttt
     1801 aacttttttt caatatcctg atgtatccgt tgctgcttcc aatgcttaaa ctttaggaca
     1861 tagtaaacaa ggaggccaat gaccagcaac actaaaatca ttattgctac ccgctgtgtc
     1921 atttttttgc ctccttgttc tattcgatca atcgtacata taccgctatt aattaccgta
     1981 actacatgtt tcttttacta gcgtttcttt ataggatctt tcataatctc atttatagta
     2041 acattaagaa tcccttattc tactatagtc acttccacat caatattgcc tcttgttgct
     2101 ttagagtatg ggcaaaatgc gtgggcttct tctgcgattt tctctgcttg gtccttctca
     2161 agtcctggca aagaaacttc taaaacaacc ccgatttggt agcccccatc ttctaattga
     2221 aataaagata cccgtgcttt gacttcagaa tcagactcaa gattattttc ttccagcatg
     2281 tgttgaaccg cgccgttgaa gcaagatgcg tatccagccg caaaaagttg ttccggattt
     2341 gtcccttcac tatggattcc tgggcggtcg atcttcatgt gcatacttcc gtttggtgcc
     2401 tcaacctcgc catcacggcc tccacgattg atcattgctg tttcgtacat ttttttcatt
     2461 gagatcatcc tttctttcgt cgttctatat taagtgtaac gagtattttt taatctgaca
     2521 aaggtaatgc ttgcattcgg cgacatcagt tagacaacat cgatgatcag tgatagaagc
     2581 agtttatcta tacaaaaaaa gaagcagcga aaagctgctc cttaagataa taggtaaaat
     2641 tgctgatata tttgacgatt aacctcttga acgtcccaag aaaaatgata ctacagcaac
     2701 aacgatgatc gcaccaatga tagaaggaat caaagccatt cctgctaatt gaggacccca
     2761 gctacctaac aatgcttgtc caattgctga accaactaaa cctgcaacga tgttagcgat
     2821 ccatcccatt gatccacctt tatttgtaat tgctccggca atcaaaccga taatagctcc
     2881 tacgattaat acccataacc aatgcataat tttctctttc tttctgtgaa atatttatta
     2941 cacatattat gttacgcttc ttcttaaaaa tacacaaaaa ttttgctctt aaaaaaacaa
     3001 aaaaaattta aaacgttgtt atattaagga taagtcaact tttttggaat cgttaacact
     3061 cactgcaaga ggtcaaaaaa actgccgcag ctctttgaaa gcgtttcgat cagcaaaaag
     3121 ttattttctg ataaagggta cctagactat gtacgatttt ctttcattgt ctgctttcaa
     3181 ccgtcatctt ccctatgaat aaaagcaatc aaagaaacct gattgtcgta cacacctcat
     3241 tcactacatc cttctgatga aacatcaaaa caattggcat tcctttgatt ctgccttttg
     3301 tatttgaaac ctgcttcccc tcactatgta aaaggattat gagaaaaagc aacgatagaa
     3361 gtgagcgtat gcaatagcga gtaaagtaaa atataaattg ttcggattgt accccggcct
     3421 ttcttcttaa tatttttcat ttctcgcttc tcccctctgc ttattggaca gtcttcgcga
     3481 ttgtgaagtc acgaaaaaaa gcaactttgc ccagcgttca atgctagaca aagttgcttt
     3541 tttattttgt ttttgaaaag tctttctttg aaagatagac agcagtaagg atgcctacta
     3601 agacagctaa cccaaaaact agaatcgttc ctatcgtgtt atccttccca ggcagtccgc
     3661 cagtgttgat cctccaaagt ccagcaatca atgatggcac tgcaaccact aatgctgctg
     3721 aatctaaata tttcatcaaa tggttcaaat tattgtccat catatccgag aatagaccac
     3781 cgatggtttc caataaatcg cgatagatcg tgacaagctt gttggcaaat ttctgtcgca
     3841 gtttaatgtc gtaaactaac gattcattat ctaatttgtc taaaaactct tttcgttcca
     3901 tcaagtgatt cactgtaaga ttctgatctt tcaacgtgtg atccaaataa accatatctc
     3961 gttctgtgtc tgccagatta aatagttcat tattttcggt tgttttacgg gcagccgcat
     4021 ccaattggtc gatttgcttt ttaatctctt tcaacccatt gatatagtgg gtatagatca
     4081 ttaatgtggc aaaagcaatg atatcctcaa aatgtcgaag ctcacttcca tgtttctcga
     4141 tcaatcgctc aacgagattc gattctctag agacataggt gatcatcaat cctttggaaa
     4201 gaataaatgt gacaggttca aggcgttttt caatgcgttc ttgatgattt gaagaaagat
     4261 cgatcaatgt ataaagaaac ggattgttta atttagtgtc tcgtaaatgt tctaatcgag
     4321 aaacttcctc tggttcatcg gagccaataa aaatatcttc cggtaaatca aaaagtgtca
     4381 gcagctcttt tttttcttct tcatttccat gtttgactac caaccaatta tagtcttctt
     4441 cggatgattc tctgatttgg ttcttttcga ttttatagta cgaatacatt ttgcctctct
     4501 cctttaactc cttcacttct cttcaactat ctaatggcga ctgctttttg tcaagaaaaa
     4561 gcgctatttc aacggttttt attaatacgg aaataaagca agcgtttgat cagaccattc
     4621 taaataaacg tgagagaata tttttgggcc caataaaaat cattttagag gaggacaact
     4681 atgtttctac atcagaaaga actacagttc gaagcaaaac cagacaaacc aaatccatta
     4741 attgcgaagt atcttcaaga attgatcggt ggccagtatg gcgaaatgag tgtagcaatg
     4801 cagtatctct tccaaggttg gagctgccgt ggagaagaaa agtacaaaga tatgttgatg
     4861 gacattgcga cagaagaaat tggacacgtt gaaatgcttg ctacaatggt tgctcgttta
     4921 ttagaaggtg caccggtaga agatcaagaa gccgcaatga aaaaagaccc agcaattggc
     4981 gcaattatct ctggaatgaa tccacaacat gcgatcgttg ctggcttagg accacgtcca
     5041 gctgacagtg tcggtaatcc atggagtggc gcttatatca ttgccagcgg taatttactg
     5101 gcagacttcc gtgccaattt aaatgcagaa tcacaaggac gattacaagt cgctcgaatc
     5161 tatgaaatga ttgatgaccg tggagttaaa gacctcttat ccgtgctatt agctcgggac
     5221 agctatcacc aaaacctttg ggcacaagct gtcaaagaac ttgaagaaaa agagggtaca
     5281 atcttagtac cgagcacttt ccctcgtaat gaagaacggt tagacatcgc ctatgacttt
     5341 tacaatttct ctgaaggaga tcaaagtaaa gaaggctctt ggggaaaagg aaaagcactt
     5401 gatggtgaag gtgaatacca atggctttct acacctaaag ttgaaggcaa agcgccaaaa
     5461 ctagatcctg tcacaccaaa aatgtatggc acgccacctg aaaaataaat tgatcgaaac
     5521 gaataaaaag agcaatgatt ccattcacaa gaaatcattg ctcttttctt gtcttattga
     5581 gcaagttggt taccttaaag ctaaaaaagc gttagagtag aatgtataag aaaaaggagg
     5641 aatcattata tgaaagcacc tttacttaca ctaaatgacg gcaatatgcg cccagccgtg
     5701 ggcatcggta cctatcaaat tcgcggtggc gaaggcttaa gccagttgca agcagcgatt
     5761 gcagatggct atcgtttgat tgattcgtca acgaactatg acaatgaagg aatcgtcggt
     5821 aaagcgattc gccgatccgg tgtccctcgt tctgagtttt atatcacctc aaaattacca
     5881 ggaaaatatc atggatatga tgatgcactg accagtattc aagaatcgct ggcgcgcatg
     5941 ggattagatt actttgacgc ctttttgatc cactggccac tgcctaaacg cggcaagtac
     6001 attgaagcgt ggcaggcgtt agtgactgcg caaaaattag gtttgattcg ttctattggt
     6061 gtatctaact ttgaacctga acatttagat gccattattg aggcaactgg tgtcacacca
     6121 gccatcaatc aaatcgagat ccatccttac tgggtccaag aacaaatggt agcagaaaac
     6181 agaaaacgtg ggatcattac tgaagcatgg agtccattag gtcgcggcag cgcggcgctc
     6241 aaagaatcca tcatcactga tctagcaaat aaatatcaaa aatctgcggg tcaagtcatc
     6301 ttacgctggc acgtcgatcg cgggattcta ccactaccaa aatcccgaaa cctgagccat
     6361 cagcgagaaa acttagctat ttttgacttt gaattgactg aagaagaaat caatgcaatc
     6421 aatcgcttga acaaagaaga tggacgtatt gaaggtcaag atccgaatga atatgaagaa
     6481 tttgagtaaa gtgagacagc ataaagctcc tgagggattt cataggctca catcaattat
     6541 aggaattgga atggtcacaa aaaaagaact gcgagatgac ttgccccaat tgaattcctt
     6601 agatctacta gcagcaaggc tctactgaag tcttgctgct attttatgag aagtaaaaac
     6661 ttctgacacg atcagttttc atttggatta tgcttttctc acagttcttt ttctgagtta
     6721 aaacttctgt acaatcagcg ttacaactga taatgaatgg cttctttgta ttgttcaaac
     6781 aatgattggt tcaattcatc gccgccatcc atatttgcgg aataaaagat gggcggataa
     6841 tcgattcctg cttgtttcaa ttgttggcaa acttcgacga taatggtatt aaggatcgta
     6901 gcgccaatca ccgttgaagt aggccccact ttttgatcca tccccttaat ctgacaacct
     6961 gcatcaccaa tttctccatg attatcgatt acaagatcag cgacttcaaa cagacgaagg
     7021 cccgaagaat ggcggctagt gactgattgc gaatacgttt tgtttgttaa agcgataatt
     7081 ttgacgcctt tttcttttgc cgctagtgct aaatcgatta tgacaggatt acgacctgaa
     7141 actgagtgta aaatcagcac gtctccttct ttgaacggct ggatttccgc taatgcggtg
     7201 ccgtagcctt ctagtcgttc cattttgcta gtaaaagtga tgggactgcg atccaacatc
     7261 agttctcgtc caaagatcgc attgatcgtc atcatccctc ccgcgcgata gtacatttct
     7321 tctgccaaga tccccgcatg actagcccca aaaatataaa tcgaatgctt ttctagattt
     7381 gctgtagtca agagacgaat tgcctcatcg attgcatgct gttccttttt ttcaacggtt
     7441 tctagtaatg catgaatttt atcaacatat tgatacatat taaattcccc caaatagact
     7501 gccgagacca cgaccaatga ttccccaaag tgatatgtca ttgccaccaa agatcagaat
     7561 ccagttttga atcgttgtgc tgaatagaac ggcagataca ccaactaaca agaccatcac
     7621 aaatgatgcg gcaatggtac caatgactgc gccacgcaag ccgccttgtc cttctccaat
     7681 aactgctgcg ccgccacatt caaagaaact ggtgataact aatggtacga tcaagattcc
     7741 aaaaacattc gtcgtattga caatgatcac aaggatcgtt gaggtgatca tagctacgat
     7801 aaaaccaata atcacggcat tcggacgata attgaatagg atcggtacat caaaagctgg
     7861 tttggctcca gggacgactt tttcagcaat cccttggaaa gctggaataa tttggttgat
     7921 caataggcgg accccataaa gcatgatcaa gagtcctgcg ccaaagttca agcctgcttg
     7981 aacagcaaac atgaccagat tcccaccttc tgggacaaga actggtgcga taattcctac
     8041 aacaatattc atcaaaaaca tcaccaaggc acctgtaatg gaaatctcac ggaaaaagga
     8101 caggttttct ggcactttta aatcttctgt cgatttttct ttgtttccta ctcgttttgc
     8161 cacgaagccg gacaccatcg ataagatccc tgtaggatgt ccaatcaaga acgaatcatc
     8221 gccagtggca tcccaaacat atttccgcat gatccaaggc ataaatgacc aataacaagc
     8281 agataaaaca gctcctaaaa tcaataatgg aatccccgac attccacctt caaccccacc
     8341 agcaacgatc acaaatggga accaccataa catatgaccc gtcaagaaaa tcgtcttaac
     8401 tggtgtaaaa cgagcaatca ataagtgcaa gatcaatcca aaaaacatag ctaacccaac
     8461 agttcccccg tattctgctg tgaaggtcac atcagaaaga ccatcggcta cttgaacccc
     8521 caactgtgtc tgaaccgctg tgttgattgg tgcgatcgtt cccgtcagca tattgacccc
     8581 tgcggtcaat gctaccatcc caaaggctgc tgtcaacgag cctttcacca cttcggcaaa
     8641 aggttttcgt tgcacgatca acccgatcat tgcaatcagt ccgagcaata ctggcggatt
     8701 ctttaaaata tgatctgtga caaaactcat gattatccct ctctttcagc taaaaacttt
     8761 tccatttgca ttttgacttc agcgacatcc atatattttt tgatgggata gacaggtgct
     8821 ttgacggaag cttgcaaatc attcaataat tcgtggcttg taaaataaac atctgcagga
     8881 gttgcttttg cagtagacaa atccgtattc tcagcagtcg ccttcagccc cagctcctta
     8941 atcaccttat cgatcgtcat ctttaacacc attgaacttc caacaccaaa tccacacaca
     9001 gctaaaattt tcatcttctt ttcctcctat tggaataatt ggcaaatctg ttctttgtca
     9061 ccattcaaaa taagttgata cttttcctga tccataaaca cttccatgat ttcctgcaaa
     9121 ctttccaaat gactttgatt gtcttttgca gctaaaacaa ggaaaatacg gaccgacttg
     9181 ccagctaaat cgatttcgtt tttagtcact agcaaactca tcccttgatg aaagacacct
     9241 tcccccggac gagcatgcat caatgcaaag taatcagcca ataccatata cgggccattc
     9301 tcctcaacgc tatggatcat attagcgaca tattgttgat cgatggcttt ttcatttaat
     9361 agcggctgac tcgccaattg aactgcttct tgccaagtga ggatttgatt cgtggtctcg
     9421 atatgatcct caggcagtaa tttttttaaa ttgatcatga ttttacctcc aacatttttg
     9481 aaatgaacca ttctttgtct tcgatccctt gcatgatcaa cttcatgaca ggttctactt
     9541 cttgggcctc atcttctcgt atcattagta acacgatgat atcgactttt tggttgcccc
     9601 aatcaacagg acgatccaaa atcaatacag aaaaggtcgt ttttgaaaca aactcaggat
     9661 tgccatgagg tatggcaaaa ccgttatcta aataggtcga ctgcaatgct tctcgttcta
     9721 agacggaacg ctgaaagtcc gtacgctgat tttccgacga aaagtcattt tgactgatca
     9781 gaaaatccag tgcttgttct ttggtctcaa atcgttcaaa ataaatcttc ggtgcaatca
     9841 acatccgtgt atcttgcagg attttcacct tatccgcaat cggttcatta tcaataatca
     9901 aatcgatata gtgattcatg atccgcttca tgtctcgatt ggtcaccatc ggcgagatgc
     9961 ggacgactgg tttggaaaca tcaggtaaat cgatcgtgga aataatgaaa tcgatggcag
    10021 aaatatccat ctctttgagc ttagcgacag aagcggtttc aatactatcg acattaggca
    10081 atattcgacg aatcttggca gaaataaatg aactggtgcc aacaccgttc ggacaaacaa
    10141 agacgatttt attcaattgc cgcatccgtt ctactgcagc ttgaaagtga atcgaaacaa
    10201 acccgatttc atcctcagat attccaatat ggtaggcctt tagaaagtcg tccaaagaga
    10261 accaaacgac cccatacaac gccggataat gctgtttgat ctcatctagc aatggattga
    10321 ctacagtagt ttgggcctca atgcgtaaaa acagctggta caaatgaatc gtcaaatctt
    10381 cttctaagcg actatcctgt gtcaaatcga tctggatgcc ttcactgact ttctgaatca
    10441 gatttctgac tttccctcga aaagagaacg gaatcgattc gttcttcata aaaaaacgta
    10501 agccactacc tacaatgaga taggttaggt actgaacttc tttcgatgaa aaatggtaga
    10561 tttcttgttc ttcaatttct ttcaacaatt cataaatcaa cggatacttg tcaaattcca
    10621 aaaacaattt tccaaattgg cgcttctctt ctatatccag ctgatttgcc tgattcgagc
    10681 gctcgacaat cagcaagatc gaaacaacga tgctttggat gtagctttct gggatctcca
    10741 tttgcttttc ggtgatcgaa tggcgaaaag ccgcatttat cttttcaaat aatgacacat
    10801 ttgtcagaac agaaaggttc tccccatgct ccacagtaag gagaatgaat cgcttcaaca
    10861 ttcgttggat ttgtgactcg cttccttgaa aataagtgcc tgaattatca aaacgcaaca
    10921 gtaaattttc tttgacaaac agtgttttta gataagcgat atccttggcg atactgctcc
    10981 tagaaacata atactcatca gaaagttgct ggtaactcaa gtgctcccca ttgatcagcc
    11041 gcttaaaaat ttgcatgcgt cggtcttcga tcaaagaata attgtttttc atttgctcac
    11101 cctctacctt tattctagtg ataccttaac aaatatgaag accaattgtt agattaaaaa
    11161 atgattaaaa ggtgtgcaca ccctttccct tgatagcaat atcggtcgtt tgttccgcaa
    11221 aatcgcttca agcaagccaa acttttctca tcttcctcgt tttctcttat aataaatgta
    11281 aacagtcaaa tgaggaggaa acaaaatgaa atggcgtggg ggtagacaaa gttccaatgt
    11341 ggaagaccgc tctggtcgtt ccgcaggttc aggaggaaaa ataatggtcg gcggtggtat
    11401 cggtacgatt gttatcgcag tcctcttttt tctattcagt gggggtgatt taaactccgt
    11461 cacagatatt ttaggaggcg gacaagccgc taattatcaa acagaaaatg tggcttcaga
    11521 cgagtataca gaggaaaaag aattctccgc tgtcgtcttc ggccatttgg aagattattg
    11581 gaatggtgtt tttgaagcag aacagactac gtatcaagat cctaaactgg ttttatttac
    11641 aggaagtgtt caatcggctt gtgggaatgc aacttctcaa gttggtccct tttattgccc
    11701 tgccgatcaa aatgtttatc tggatctcag ctttgcaaca gaactttctc aaaagtatgg
    11761 ggccagcgga gattttgcca tggcctatgt cattgctcat gaagttggtc atcacgtaca
    11821 aaacgaactt ggtattacac agcaactcga taagatccgc caacaggttt ctgaaaaaga
    11881 atacaatcaa tatagtgttc gtttggaact acaagcggat tatttagccg gtacatttgc
    11941 caagtatcta caaggaaaaa cttataacgg ccaaccgatt ttagaagctg gtgatatcga
    12001 agaggctatc acagctgcta atgccattgg tgatgatacg ttacaaaagg aataccaagg
    12061 atatgtcgta ccagatagtt ttactcatgg gacttcaaaa caacgagttg aatggttcaa
    12121 ccgggggttc aaatatggtg atttggagca tggagacacc ttcaatgaaa aaaaccttga
    12181 tttggtctac ggatcataac aaaaacgttc ctttttagtc actctttttt cacatttggg
    12241 cggtatagtt tattcatacc aacaaaccct aactttttca ttttactcct tgcctgccag
    12301 tccccgctgg caggcccttt tttttcatgg tgctatttta gtttttttta acctttggcc
    12361 tgtttttttc tttaaaacgc taagggttga tcacaatttt ttcatatttt ccggttacta
    12421 tataaataac ccaacaaaca acccaacttt ttcattttta ctccttgtct gtcagtcccc
    12481 gctgacagac ttattttttt tcttgccaaa attctcaaaa tgcgctaagg ttatttatgc
    12541 gcggaagtgg cggaatggca gacgcgcacg cttcaggcgc gtgtgagtat atctcgtgtg
    12601 ggttcaactc ccatcttccg cattttgagc agatcatctt ggatgatctg ctctttttta
    12661 tgtgtttctt ttgtctaaat aaagaaaaaa gcttaagcta tataaattga gttaaattgt
    12721 attcgttttt cctcctatag gcgtatacta aagaaaacac ttgaggagtg gggaacatgg
    12781 aaacagaacg ccaaatccgt gaattggaaa aagcgatgaa tacgacagac aaccgccggt
    12841 tgtacgagcg tttcctggca gtcaagttgg ttcttgaagg ccacacccgg aaagaagccg
    12901 ggcacaccat cggccgcgac gagcatactg tcagccacta tgtgaaaaac tactgccata
    12961 atggaatcca aggtttagtc tccaaaaaac aaagcggacg accttcacgg ctgacagatg
    13021 aacaggaagc ggaactggtc caaatcgtcg cctaccacac tccggaggaa gtaggtttca
    13081 aatcccgtgc caattggaca ttggcgattg tgtgtgacct gattctccgg gaatggagtt
    13141 atggatatac gcaaaaaggc gtggcggacc tacataactt tccccctaga tattacgaat
    13201 atccaggggg tgttattgca tgcgtaacag cctatgctaa tttacaacat agatcgaagt
    13261 ggcttagctc taaaaaataa gccgcatctt tgtcagatac gactgtttag cattgctcat
    13321 tcaattagtt gatgattttt tcatcaaatt tcagatatag ttgaatattt cctttgttca
    13381 gcttatcaaa tgtcacttta tcaatgaatg ttcgatagat ttccttgttc tcactcttga
    13441 aacgattggc taacaacttt tcaacacttg ctcctttgtt tcgaaatgga ggctactcat
    13501 caaaaagaat aaattcacgg tactttctag agagtattga tagcaaaata tttaatccaa
    13561 tcattgaacg acttccttca attaaattgc ttggaagctc tcttgtctca taatataaca
    13621 aaaagtcgga atgctcgctg aggaaatttt ttcccagctc agtaactccg caaagtggaa
    13681 ttcggttcat attcaaattt ttgattgttg atttgatgct tggtgtctca ccgcttagag
    13741 acgtaacgat cacaaaatca tcttttgtca aagtatggct taacatttca aagtttgttt
    13801 cacctgaaat taacatggct ggtcgtcccg ataaaatcaa atcgtttaca aagtcttttg
    13861 aaaagttatt ttgcgtaaag cctgtcgcat agacaactac tgtttttgcc gcttttagct
    13921 gttctaatat cggttggaaa tttgtttggt ccgctaattg aaaagttcgg ttgatttcat
    13981 ctttcaatag tgcgataaga tctgtcggtg gaataaccga ttgaacgatg ctctgttcaa
    14041 gagaatattt catttcagaa tacccacgaa atcccaattt ttttgctaaa cgtaagacag
    14101 aacttttaga agacaataat tgttctccca attctacaat ggacatgtga actacttgag
    14161 ctttatgcgt acgaataaaa aaaaccatat ctttttcatt atctgagagc aaatcaaagt
    14221 ttagtcgaac attttgttca aaatccattt tctcacctct catatataca gaaggaattt
    14281 cggataaaac ttgcgctgtt ttatccgaaa ttctttctta ttgcccaaat tctaacacag
    14341 tttttacgtg cttgctatat atgataaaca agtgcttcgt aaggtcgtaa tataaactta
    14401 tcttccaatt cagatggtga ttgctcataa tttgatagaa gaagaacccc ttttcgacct
    14461 tgcaatgatt taggtaattc atagggaaca gactcttttg aaaaagaaca gatcaccact
    14521 aatagttcat ttttatactc acgtatataa ccaaacactg ctgaatcatt ctcattgatc
    14581 aatttatacg taccatgctg aatgattgga tagtttttac gcagtgaaat cagtttttga
    14641 taatgataaa aaactgaatt tggatttttt aaagcatctt ctacattgat ttgttgatta
    14701 tctggcgaaa aagagatcca aggatcactg ttcgagaatc catacccttt tgaatgatcc
    14761 caaggcattg gtgttcgtgc gttatcacga gatttcaaat aaatagcacg tttgatgtac
    14821 tcatcactct cgccttcttc tttcatcttt ttataaaaat agtttgtttc aatgtcttga
    14881 tactcatcaa ttgaagaaaa tggaacattt ttcattccaa tttcttcccc ttgaaaaata
    14941 aatggggttc ctttcatcat gtgaagtagt gttcctaaca tcttactaga ctctatccga
    15001 tattcgtttt catcaccaaa tctagtaaca gctcgcggtt gatcatggtt actccagtaa
    15061 agagaattcc aaccatctga aagcgcttct tgccactcac ttaacgtagc tcttaaatcg
    15121 ctaagcttaa accttacatc tgaaaacttt ccatactttc cataatcaag atgcatatga
    15181 tcaaaatgaa aaaccatatt taattcttta cgctcaggaa acgtataaag ctgtgcctgt
    15241 ctgctatttg tgttcggtgt ttcaccgaca gttaagctgt catatttact caaaacttct
    15301 cgattcatct cttgtaaaaa ttcatgcact cgcggaccgt tggatgctcc gacataataa
    15361 gactttgtat agggcatgct atttggagca tcaggataat caggatgctt gctaatcaag
    15421 ctgataacat ccattcggaa tccatcaatt ccaagatcaa accatttttt catcatttta
    15481 taaatagact gacgaacttt cgggttctcc cagtttaaat ctggttgttc ttttgcaaaa
    15541 caatgtaagt aatactgctt tctactctca acatactccc aagccgaccc gccaaatgtc
    15601 gatccccaat tcgtaggtgc actcccatct tctttgggat ctttccaaat ataataatca
    15661 gaatatggat tttctttatt tttttgtgat tctataaacc aagcgtgctg attacttgta
    15721 tgattgacga caaggtctaa aataactcga atattcagtt gatgcgcctg ttccaataat
    15781 ctcttaaaat cttctaacgt tccataattt tctgaaattt tctcatagtc tcgaatatca
    15841 tatccgttat caattagcgg agagtcaaaa attggagtta gccagataac atcaacccct
    15901 aactttgcta aataaggtaa tttttcaacg atccccataa gatctccgat gccatcattg
    15961 tttgaatcct tgaaactttg aggatacact tggtagacaa cactactttt ccaccattca
    16021 ttcatccgtt actcatcctc ctcatcaacg actatatttt ttaagtaatc attgacataa
    16081 accaattggt cttgtgcttc ttggattgcc tcacggatgt ggttgtctgt caatcttttg
    16141 tttaatgtat tcaataaaat tgtcaatacc acaggtagat tcatcccggt aatcagatag
    16201 acattaggtt gattgatata ttttataaat gcttgattga ctgaaccacc tagcatatca
    16261 gtaaaaatca atatatcagt atcctcattg tctcttacca ttacttcgtt aatcttttct
    16321 tctataggtg agttatcaat ataacctgcg attgcagtta tttcaccaac attcggtaaa
    16381 atatattgga cagtatcttt caatcctaca gctaaattat gatgactagc aaaaataatt
    16441 tttttcattc tttattctcc ttaaaccttt aaaataccga aaaatgatag aatcaatgcg
    16501 aatatgatca ctgaaaaaat aatttgaatg accgtcattt tttttgaagc tatcaattta
    16561 taaacaataa ttgttaaaac tgcaggtaag agtgctggca tgattttatc aagaatttct
    16621 gtttgaatag gtaattttac ttttccagat tgaaaaacca ctgcaacatt catttttaca
    16681 acagatggaa tcaaagctcc aacgactgtc aaacccataa ttgaagcaga ttctgtaaat
    16741 atcgataatt tacttcctaa agcagtcacc aactttaacc ctgaagtata cccaatcgaa
    16801 aaaagtttaa atcggaagaa caaaaagaat agattcaaac ataaccaaat aatggcacca
    16861 gtcggatttc cttctagacc catataagct gcaatcgagc ccataatcgt tggataaagg
    16921 acccaaacca acgtgtctcc cacaccagct aaaggaccca tcatcccagt cttaaaactt
    16981 tgaactgcat ctaatgaact gactccatct ttttcttcca ttgctaagct ggcacctaat
    17041 aataaattcg ccatccaagt cgttgtattg aaatatttaa aatggttatt cagagaagct
    17101 ctgtagtctt catcatttgg ataaattttt cttagtgctt tttcaagtcc ataaacaact
    17161 gccggacctt gttgattttc gtaattgaag atattacatg ccataaacat atagcgaaat
    17221 gctgctctac gtatatcttt ctttgataat ttatttcctt cattattcat caaaatcatc
    17281 tccttcatcg actatattgg cagctacagg tgatgccgtc tctgcttttt ttatttctgt
    17341 cgtgaaaaag taatacgcta aagcaaagcc gacgattgaa attcccaaaa taggcatgtt
    17401 taaataggcg gaaagtacaa aaccaatcaa gagcatcgtc atatattttt tcaccggcat
    17461 aacttgtaga agtaatgcta ttccgactac aggcaacatg cttccagcaa tcgataatcc
    17521 atctgtaaac cacttaggca caaaatctaa aatcaatcga acaattctat caccaaaaac
    17581 aacacacaat gcagttggaa tggctgtaga taatccgaaa atcactggtc ctaaccacaa
    17641 aatctgattc attttcttaa aatccatttt atttgctgcc ttttgtgccg catgagtaac
    17701 atatgtgttc aatattttag ccaacacatc taattgaatt cccagcatcc caacaggaac
    17761 acctactgct aatgcaacag cttttgcttc ttcaatatta tttgtggtac ggatggctac
    17821 gtagatacct acaagagcag ctaaacccca gttaggaacg gacgatcccc caatattcgc
    17881 tacacccaaa gccattaatt gaaacgtacc gccaataacc attgcggttg tcatatctcc
    17941 cataatcagc cctgcaaaca aagcaatcat gatgggaaac catgttgtaa tgaccaatcc
    18001 ttgttgatct aatacaaccc acactgctaa aataataatt aaaattcctt ggataatttc
    18061 cattccaatt atctccttta ttttattctc acatctaatg gttcttcagg atctgaagga
    18121 acaaaatgaa aagtaactgg tattcccata gcctctaatt tttttaaatc agcaatttct
    18181 tgttcatcaa ctgaaaccat tttttttact gtttgtttcc cttcaccatc aaacatgatc
    18241 ccgatattca cttttggtat atcgataccg ttctcagcta gttttactaa tgtactcggt
    18301 tcttttacga tcataagcac attatgactg tcatacttgc caagtttgaa attaataata
    18361 gctgtatctg tatcaataat tgacatcccc gttccagctg gcttactcat tcgcattgct
    18421 gctttttgtg tgtcatcctt actgacttga tcatctacga ccatcaatcg ttttgctttt
    18481 gtcgcacctg cccactgtgt taccacaata ccgtgaatca atcgttgatc gattcttgct
    18541 aatactaatc ccatatctat cgtctccttt tttgttatcg tttacatccc aaagtatatc
    18601 tacgccttgt tactttaaca atagttttag aagtatcagg gaaacagtcg ttatcttagg
    18661 aaatagtttc tttattaaga gaaatttccc acaaaaaaat agcccaacca tcgattagat
    18721 gactgagctc cctaaattta cgctatcttt tattactatt tacttctttt ttatcgcaat
    18781 ccaaatttcg ccatcacaat ccgtcaactc ttttgagaaa tcagtaaagg agagttctga
    18841 tgcttgaacc aactcatatt ctgaagttgg caaccactcc gcgtatattg acccgctgac
    18901 atccctaaaa aaggtgcgag gtggagaata tttttgatac aactatcctt atttatgata
    18961 tggagccccc gcattgatcc ggaaggcacg gtagatttgc tcgacaagga tcagacgcat
    19021 caattgatgt ggatacgtca tttttccaaa agagatgtga gcattgcttc ttttcatgac
    19081 ggcttcgctg agtcctaaag agccgccgat aacaaaaaca aggtggcttt ttccttggat
    19141 acctaattgg tcgatttgtt tagcaaaaga ttcgcttgtg ggatttttcc cttcaattgc
    19201 taaggcatag acgtattctt gttctttgat tttcgctaag atccgttccc cttctttttc
    19261 ttttacttgt ctcatttgcg cttcgcttaa attctccggg gctttttcgt caggaacttc
    19321 gatcaattcg atttttgcat aggcattcag ccgtttgaca tactcattga taccttggat
    19381 caggtatttt tcttttaatt ttcctactga gataattttg atattcatgt tttctctcct
    19441 ttggtcttca tgctcacttt gtttattata atcaattttt tcgtctatat gtttattttg
    19501 gctatttttg ttaaaaagat ttccccaaca gttatgcaca acatccacag gtttatccac
    19561 agaaaacagt gttattttac cttatttcat cacatttatt aggcaaacat acgttttata
    19621 agaatttatc cactttatac acaggctgtg gatatgtttt atcccttatt tttccaatcc
    19681 tatccgcgta gttttacaca gtttctgtgg aaaaaagcaa atcaaatatt ttcatctgaa
    19741 aacaatggtt tttcctaaag tttttcataa aaagttcaca gtctcaaagt agactaaagt
    19801 caacaaataa gagtatacta acagtagata aatgaatgta attggaggag gaacacatgg
    19861 atagaaaaaa tgtgacacca aagatgaaaa aaaataaaaa taatagcctc tggcgtaagt
    19921 taggtctagg gcttgttgga gggatcgttg gaggattact gacagctggt attttttatg
    19981 cagcgatggg cactggcaac aatagttcta ctacaagtgg caatcaaaat tctgctggtg
    20041 aaacagttgt ggaaaacgtc aaagtcaatg tagattctga tatcaccaaa gcagtagata
    20101 aagttcaaga cgctgtcgtt tctgttatca acttgcaaag tcaaaaccaa tcaagcggtt
    20161 ttggcggact attcgggcag caagaagaaa gtagcagctc agatgatagt aatttggaag
    20221 cttatagtga aggaagcggc gtgatctaca aaaaagacgg gaatactgct tatgtagtca
    20281 caaacaacca cgtagtagat ggccagcaag gtcttgaagt cttgatgaaa gacggtacga
    20341 aggtaaaagc tgaattagtt ggaacagatg cttattcaga tttagcggtg ttgaagatca
    20401 attcagacaa agtcgaaaca gttgcctctt ttggtgactc aagtgctctg aaggttggtg
    20461 agcctgcgat tgcgattggt tccccattag gatctgaata tgcgaattct gtcacttcag
    20521 gaatcatttc ttccttgaac cgacaagtaa caagtacaaa tgaatcgaac gaaacagtca
    20581 atatcaatgc gatccaaaca gatgcagcaa tcaaccctgg aaattctggt ggtcctttag
    20641 tgaatatcga aggacaagtt atcggtatca actcaagtaa gatcgcaagt acttctgaat
    20701 ctacttctaa tgtaagcgta gaaggaatgg gatttgctat tccaagtaac gatgtagtga
    20761 atatcatcaa tcaactggaa aaagacggaa aagtgacacg tccagctcta ggtatcacaa
    20821 tggtcgactt atctgccgtt tctactcagc aacaagaaca aatcttgaag attccttcat
    20881 ctgtaactaa cggtgtcatc gtgacaaatg tccaaacagc tacaccggct gaaaaagctg
    20941 gattgaaaaa atacgacgtc attactaaga tcgatgacaa agaagtttct tctggtgtag
    21001 aacttcaatc tgctttgtat aagaaaaaag tgggagattc tgtcaaaatc acttactatg
    21061 aaggctcgaa agaaaaaaca actactgttg aattgacgat cgatcaatcg gcattaaaac
    21121 aaaatcaaaa tagtgaaaat taataaaaaa gaggttaggt tgtggcaaag acttgtcaca
    21181 acctaacctc ttttttataa actatatttt tcttgccaac tcctcggtca caagtcacaa
    21241 gatccaacaa acatgagaag ctgttttttg aaattgctcc ttgtgactca gagtgaaacg
    21301 gcagactcac aacctcttta ttttggaaat gcttctccga ctacggcatc ctcaggcaat
    21361 actaagattc ctttttttgc tggagcattt ggcaaatgca attcacgagc ggaacagatc
    21421 attccatagc tatctacccc tcgcaaagtt cctggccaga tcatcattcc atctggcatc
    21481 atagctcctg gttttgcaac gacaactttt tgtccagctt cgatattggg tgcaccgcaa
    21541 acgatttgca atactgtacc attgtctact tctgtctcag taatcgataa atggtcagaa
    21601 tcaggatgtg ggacgcatgt ttttacgtac ccgacaacga tcttcggttc atgatcagct
    21661 tcaagctgtt cttcgaatcc tgcttctttg atcaatcgat tcaatttcgc taattcctca
    21721 tctgttaagc ttacttggcc gttcccttcg attgttagat gatcggagat atggaaaaag
    21781 ttccaagcaa caacttgacc ttgttcatct ttgatccgag caacattcca tttgcgttca
    21841 acagtgtttt ctgttccttt atcgtcggct ataataacca tcaaggtgtc tccgacgtgt
    21901 gctttgttat aagcaaaaat catgttcttt cctccattat cctttgctga gatttatctt
    21961 aacaaaaaat tgcattcact gcatgagatt tttttcatgc tttatttccg aagaagcctc
    22021 ttctggaaca ccatttattc gtaacaaggg actgtgacaa gacttttgtc acagtccctt
    22081 tactgtttta gttaattgat taaaaaggtc gtacaagttc cacttgctta attacttggc
    22141 tgttcttctt cgtcagaaac gatcaagaca tcacaaggtg aatgacgtat cacgtagctg
    22201 gctacacttc ctgtcataaa gcgttcgact gcatttagac ctgactgccc aaccatgatt
    22261 agatcgatct catatttttt tggcaatttg actgccatgg attcacgaac agaaccatat
    22321 gcaataattc cttctatatt tgtgtaatca acagatttcc catattcttt acattcttcg
    22381 atcatttcct tggctgtttc agtttgctga tcgactagat tttgatcaat aggtgcatag
    22441 cccataaagt tataaaattg ctgatcgatt acgtttgcta catatacttt cccattatta
    22501 cggcgagcca cttccaccgc ttttttgaaa gcagcaagtg cttgttcact accgtcgata
    22561 cctactaaaa tgttcttata ttcttgattc atcttgaccc ctcctaacag atgtcagcct
    22621 tttgtcacac tttctaggaa cgattcgatt tcctgttttg ttttacgatc tttattcact
    22681 agacgaccta attcttttcc gtcttggatc acgacaaaac ttgggatacc aaaaatgttc
    22741 cattcagcgg ctacatctat gtacttgtca cggtctactt caataaattg ccaatcagaa
    22801 aagtcatttt caatttcagg catttgcggt ttgataaaac ggcagtctcc gcaccagccg
    22861 gcagtaaaga aaaatacact ctttccagtt tctacgtagc ctgctaattc ttctaaacta
    22921 tttgggataa tcattctttg tcctctactt tctgtttatg tatttttcaa ttaaattata
    22981 cacctttctt tcgaactaac aaacattgat cctcttttta taaaaaaaat ctggcaaaag
    23041 caatcttttg ccagatttta tagtttcact atcgcattat tttccgtata cgatcgtatt
    23101 cactgttgat ttatccaaac ctttcagtgt ttgtatcaac atttctcgtg cagcttcaaa
    23161 atcgcgaata ctgaacatcg tttgatgcgt atggatataa cgtcccacta cgccaatcac
    23221 tgtacttggg attccttcgt tttgtgtatg agcagcacct gcatctgtac cgccttttga
    23281 aacaaagtat tgataaggga tattgtttgt ttcagcgata tccagcaagt actcgcgcaa
    23341 acgaggaagc atgatcaaac ctggatcttg gatacgcatc aatgtacctt ctcctaaatg
    23401 tccgaatgtg ccatttttcg tcactgtatc atctgctgca gagcagtcta ctgcaaagaa
    23461 cagatctggc ttgaatttat tgacagaagc tttagaacca cgcaagccta cttcttcctg
    23521 gacattcgcg cctgcgatca atgtatgccc taatgtttca ttttgcaacg cttctaaagc
    23581 ttctaatacc attgtacagc catagcggtt gtcccatgat ttgctgatga tattctttcc
    23641 gttggctgtt ttgatcgttt cagcgtaagg aacgattgtg tctcctggaa ggacaccgta
    23701 actcattgcc tcttctcttg attcaaaccc agcatcgaac aaaatatcgg ttacttctac
    23761 tgatttttgt ccgcttgttc ctcgcaataa atgcggggga acggaagaag aaatacatgg
    23821 ataattctta ccagtagagg ttttaagtgt aaaacgctgt gcagaaacaa cgtaaggatt
    23881 ccagccgcct agaggtacga ctttaaaaag cccgttttct tggatttgtg tcagcatgaa
    23941 tccgacttca tccatatgtg ctgcgaccat tacacggggt gcatccgctt cttcatgatg
    24001 gcgcagacca aaaatgccgc ccaaaccatc taactgtaac tcatctacca gcggttccat
    24061 atgactttcc atataagcgc gaacatcttg ttcaaaaccg cttgttcctt gtaattctgt
    24121 taactctttg attcgttgaa atgttttttc ttccatatgc tattcgtcta aatttcagac
    24181 taaactcctc tcagacttat attgatctgc ggataaaata tgattttttc tgcagaccga
    24241 tcgtatttat tatagcttat tttttctggt agcggttatt tatttcaaag aaaatatgag
    24301 agtgtggtaa aataagcaca aggagtaaca agtgagaaga aggaggtatg tccacatgta
    24361 tgaagaaagc gaactaagct attttaaagg cgggttagca gttggaatcg gtctaggatt
    24421 attgagcggg gtagcttcaa cgatttggta tcatcgcaaa aaagtattgt cagcagacca
    24481 agtacttgaa aatatcaagt catcttttct aaaagaaggt gcaatcgaag gttcttggat
    24541 ctcttttgaa aaggaaccta ttaggaaatt cgccgttcgg tcgagtgctt atcggggagg
    24601 tctttctcga atagaagatg gcgaaactgt ttattatgaa tttttagcag atgctcatac
    24661 aggaaccgta ttagaaattt caagaaaaaa aggtgcaaca gattaatacg tcaaaaaagt
    24721 gagagaacga atacgcaccc actattcaaa agagaggtat cctatacttc ttttatagtg
    24781 ggtaattttt ataaaaatag ggctatttcc tcttggaata gctagtatta tagttattat
    24841 at
//
LOCUS       DAXLPY010000037        24665 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.037, whole genome shotgun sequence.
ACCESSION   DAXLPY010000037 DAXLPY010000000
VERSION     DAXLPY010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.037"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            236..1042
                     /locus_tag="ACF3UF_001634"
     CDS             236..1042
                     /locus_tag="ACF3UF_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671747.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1054..2274
                     /locus_tag="ACF3UF_001635"
     CDS             1054..2274
                     /locus_tag="ACF3UF_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671748.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     NKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2264..3850
                     /locus_tag="ACF3UF_001636"
     CDS             2264..3850
                     /locus_tag="ACF3UF_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3671749.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVVQTSIAQPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSEAT
                     ERMVFRFAQQPSFIEFSAEAAGEKLIFIDSNAVVKTVNDCYLFDGKEIPEFALTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENQHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKKTSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSRDEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            3889..6027
                     /locus_tag="ACF3UF_001637"
     CDS             3889..6027
                     /locus_tag="ACF3UF_001637"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3671750.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKIRLSGKMRGKAILDFQTAKHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKTIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNIHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKKLGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            6315..7706
                     /locus_tag="ACF3UF_001638"
     CDS             6315..7706
                     /locus_tag="ACF3UF_001638"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFD3671751.1"
                     /translation="MNKNGEWNAARRIFIIIMDVLVLNVSIYLSFLLKFQGEVPARNL
                     ETFQHSAVFISIIFIALNILLGAYVFYSRVISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVIVLSFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVVIDKYYENTKKLIDDIDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFKIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSVTAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENIRS
                     LAEIDFSQEKIYR"
     gene            7765..8574
                     /locus_tag="ACF3UF_001639"
     CDS             7765..8574
                     /locus_tag="ACF3UF_001639"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3671752.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFNHMTVMFD
                     KNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYARRGGSKYL
                     LPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN"
     gene            8546..9535
                     /locus_tag="ACF3UF_001640"
     CDS             8546..9535
                     /locus_tag="ACF3UF_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3671753.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLKRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNCGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNYPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQKE
                     KQKYYNQSKREIKSIYSKIRSNNEISIAKKLALFLYLINPKTYFILYKKVLKK"
     gene            9649..10644
                     /locus_tag="ACF3UF_001641"
     CDS             9649..10644
                     /locus_tag="ACF3UF_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3671754.1"
                     /translation="MHKISVIVPAYNVEDYLENCLESISNQTHSNIEIIVVNDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILIFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPDFSPKLKKLVKFLLINKNLPYYMSSSKIASKFLIKIESVR"
     gene            10648..11790
                     /locus_tag="ACF3UF_001642"
     CDS             10648..11790
                     /locus_tag="ACF3UF_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HFD3671755.1"
                     /translation="MKNIKKFFSRNIFPVFIKILPIQKNLIVFSSFGGRNYSGNPRVI
                     SEKIHEKKLNYRIIWLIKKEAIITDLPDYIKRIDSDSFLAAFYLYTAKYWIDDSRKTI
                     KYAKRKKQLYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITYLLSGNRYSSKK
                     YVSAFNIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFRNNIEDNGITQL
                     EWLGVDNLREFFKKQQQELNFMTKFHPNVHSKLATDSKSIEYMKKHQITLINDGIPLE
                     MLFEEIDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQLSELPIISVQDS
                     YGLVDVFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELIERDIK"
     gene            11787..13214
                     /locus_tag="ACF3UF_001643"
     CDS             11787..13214
                     /locus_tag="ACF3UF_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3671756.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFIQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIVGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIIIFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPIFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTELSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVILFFIVNLTLTTWAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEIRKITRK"
     gene            complement(13281..13433)
                     /locus_tag="ACF3UF_001644"
     CDS             complement(13281..13433)
                     /locus_tag="ACF3UF_001644"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3671757.1"
                     /translation="MLITKLENLRTHIKTLKRFAYGFRSFTNMRLWIFLINRLISYAL
                     KASNSY"
     gene            complement(13536..14336)
                     /locus_tag="ACF3UF_001645"
     CDS             complement(13536..14336)
                     /locus_tag="ACF3UF_001645"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3671758.1"
                     /translation="MRLRKQHYHYQSCGKYFTAHTYLVVPSCFISKQVHYTILEELTE
                     RQALKTLTKRCDLSVTTFQRTLSALSAMLRQMLDYLPHCLLFDEFRSLSISHGKFSFS
                     CMNRETGKLFDILSSRRKKDLIAYFMRFTRKAHMGVRYIVTNMNAPYFSLVKESFPNA
                     QIIIDCFHIGQHLNKFFDRVRKRVMKQLNQKDTSQAKYYRQLKPLYKLLLKSDDELDY
                     TTFKKWQNFQWRYLTESEVVDRLPSISYELKIAKQFIKSCLAIITRNS"
     gene            complement(14750..15160)
                     /gene="tagD"
                     /locus_tag="ACF3UF_001646"
     CDS             complement(14750..15160)
                     /gene="tagD"
                     /locus_tag="ACF3UF_001646"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0047348 - glycerol-3-phosphate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HFD3671759.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGQFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            15286..16677
                     /locus_tag="ACF3UF_001647"
     CDS             15286..16677
                     /locus_tag="ACF3UF_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFD3671760.1"
                     /translation="MLNEKFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFAINIFIQFS
                     FIALSGSRTTLVCLLIATFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAQAWAHVPHITEIKKDISDSSGTTSSNKVDLKRPDTDGGDVSNLRFGLWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKTLRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            16810..17757
                     /locus_tag="ACF3UF_001648"
     CDS             16810..17757
                     /locus_tag="ACF3UF_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFD3671761.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDME
                     KQVTFIEGDVSDPQLMERIMKQYQFAYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFASEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(17797..18957)
                     /locus_tag="ACF3UF_001649"
     CDS             complement(17797..18957)
                     /locus_tag="ACF3UF_001649"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFD3671762.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            19122..20297
                     /gene="mltG"
                     /locus_tag="ACF3UF_001650"
     CDS             19122..20297
                     /gene="mltG"
                     /locus_tag="ACF3UF_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFD3671763.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPNGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEKAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            20433..20912
                     /gene="greA"
                     /locus_tag="ACF3UF_001651"
     CDS             20433..20912
                     /gene="greA"
                     /locus_tag="ACF3UF_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFD3671764.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            21080..21811
                     /gene="liaF"
                     /locus_tag="ACF3UF_001652"
     CDS             21080..21811
                     /gene="liaF"
                     /locus_tag="ACF3UF_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFD3671765.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            21808..22875
                     /gene="liaS"
                     /locus_tag="ACF3UF_001653"
     CDS             21808..22875
                     /gene="liaS"
                     /locus_tag="ACF3UF_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFD3671766.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEIAKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            22882..23514
                     /locus_tag="ACF3UF_001654"
     CDS             22882..23514
                     /locus_tag="ACF3UF_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3671767.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDCPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            23654..24319
                     /locus_tag="ACF3UF_001655"
     CDS             23654..24319
                     /locus_tag="ACF3UF_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFD3671768.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            24347..24640
                     /locus_tag="ACF3UF_001656"
     CDS             24347..24640
                     /locus_tag="ACF3UF_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFD3671769.1"
                     /translation="MELTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
BASE COUNT         8418 a         3663 c         4781 g         7803 t
ORIGIN      
        1 aaacgaagaa aaagtgttag tagaaaatcg ccttcgattt tccaccaaca caaaatatta
       61 tagaacccct tttttggttt attgcaattg tctagcatct tctgtaaaat agaaacgtta
      121 gagaaaatct tgtatcatag aaaattaaga aagaaataag aacgcagctc ggtaccaaaa
      181 atatggtaaa atggcacttg actgtaattc actgaaatcg cttggaggaa cacaaatgtt
      241 taaagatttg tatttattta tgaaagacat ttatcagaat agaaaattac tgctacagtt
      301 ttcgatcaat gacttcaaat caagatatgc aggatcgttt ttaggaatct tatgggcgtt
      361 tatcaatccg ctatttactg tattgattta ttggctggta tttggtgttg gactgaaagc
      421 acaaatgatc gatgcaaaat acccatttat cgtatattta gttaccggga tgattccctg
      481 gttcttcttc tcagatgcat ttgcatcaac tacggttgtt tttcgggaat atacttattt
      541 agtaaagaaa gtcgtattca atattcgtat cttgcccacg acgaaaatcc tatccaatct
      601 gtacacccat ttattcttca ttctgattgg catagctgtc gcgcttataa atggtatata
      661 tccttcagca atgtctttac agctgattta ttatttattt tgcatgtgtg ctttcttgac
      721 aggattgact tggctgacgg catcgatcca accattttta cctgatatca tgcaattaat
      781 tacgatcgtg ctgcagttga tcatgtggac attaccgata ttatggagcc ctaatcagtt
      841 tgattcaggt cttgtaagca tattgaaatt aaatccgctg tactatgttg ttcaaggtta
      901 tcgtgagtca tttttaagtg aagcttggtt ctgggagcat ggaacatata ctttgtattt
      961 ctgggttttc acgttagtaa tgttcgtaat cggctctgca gtgttccgta gattgaaacc
     1021 acatttttca gatgtgctgt aaggagaata gctatgacag aatatgcaat tagactaaaa
     1081 gatatcacaa aatcttataa tatgtacgca aaaccttcgg atcgatttcg tgaagccctc
     1141 aatcctttta agaaatccta tcatgatgta ttttatgcgt tgaaaaacgt gaatgtagaa
     1201 ataaaaaaag gtgagatgat cggtttcgtg ggagaaaacg gatcgggaaa atctacaatg
     1261 ttgaaaatca ttacgggagt actgacacca acatccggca cgatggaaat cgaaggaaaa
     1321 atctcagctt tgctagaact aggatcagga ttcaatcctg agtattctgg ctatgaaaat
     1381 atctatttaa atggaatggt tctaggattt tcaagagaag aagtcgatga aatggtcgat
     1441 gatatcattg aatttgctga tattggcgac catatttatc aacctgtaaa aacctattca
     1501 agtgggatgt tcgttcgtct agcttttgct gtagcgatca atgtgaatcc tgatattttg
     1561 attgtggatg aagcattggc agtaggagat cttgaattcc aactgaaatg tatggaaaaa
     1621 tttacagaaa ttaagaactc gggaaaaacg attttattcg tttctcatga tattagttcg
     1681 attcgccgtt tttgtgatcg ttcctattgg ttgaaaaatg gagaagttgt cgaatatggt
     1741 gatacgatgg aagtaacgac gaattacgaa aactttttga agaaaaaatc agttaaaaca
     1801 gtagatcgaa ataaaaacca agtagaacgc ttcgcagctc cagatatcgt agacgtgacg
     1861 aaagccgaat tgttggataa aaataaaaat ccagtggata tgctggaaca aggagaaaaa
     1921 ctatacgtta aagtaaccta tgaagtaaaa gacgatacaa tcaaaaatcc agttttagga
     1981 attgctctgc gtacagtcga caatttttat gtgtgcggac tcaatactct actagatggt
     2041 atcaagatcc cttggaaaaa aggtgagaat atcttttatc tggagtatga aaagttaggt
     2101 ttgttagctg gtgaatatta ttttgacgtt gcggtctttg aagaaaatgc aacggttcct
     2161 ttggtataca agacaaaata catgaacttg tttgtcagcg gttcttatat cggagaaggc
     2221 atcgtggtct tagaccataa atgggaagaa gggactcata gcaatgaaat atgattttga
     2281 aatggaccta gatgaacaaa gcagtgtggg aaaaattgcc gcacagatca aaccaggaag
     2341 taaagtttta gagtttggtc ccggaaacgg tcgattaacg aaacatttga tcggagcaaa
     2401 acaatgtgaa gtgagcattg ttgagctaga taaggaatta ttcgattttg tcagcgaatt
     2461 tgcccaagat ggattttatg gagatatcga aagttttgaa tgggcaaact attatgctgg
     2521 acagacattt gattacgtct tgtttgcgga tgttttagaa catttagtag atcctggaaa
     2581 aacattgaag aaagtcagag aatttttgaa tgaagaagga gagatcctga ttacattccc
     2641 taacttagca cataattctg tcatgatcga tttgttcaat aatcaattgc cttgggcttc
     2701 ttatggtctc ctagatgaaa cccataattc tttttatact catgatggtt tccaaaaagt
     2761 ttttgaaaaa gccggattat tcattaatat tgaagattac ttgtacttgg ctgtaggaga
     2821 tacagaatta aaatcaactt atgaagagtt gccggaagct gtacgctatg atttcaaaat
     2881 gcgaccattt ggtgaagtct accaatactt tttctcattg atgaaacatc cagtagtaca
     2941 aacttccatt gcacagccac aaaactctaa ttatgtaaaa gtactagaag taacccagca
     3001 aacgaaacaa gatgaaacaa tccaacaaat accattcaat aatttcacag gggaaaatga
     3061 gacactaagt ttccccgtgt cagaagcaac agaaagaatg gtgtttcgct tcgcacagca
     3121 acctagcttt atcgaattca gtgcagaagc tgctggagaa aaactcatat ttatcgattc
     3181 aaatgctgta gtcaaaacag taaatgattg ttatttgttt gatgggaaag aaataccaga
     3241 gttcgctcta acggatattt ctgggaaaga agtgactatc cattgtcact atcgctttat
     3301 cggggaattg acaccaacaa tgaaagaatt gctggaaaca attcgtccta tggctgaagt
     3361 cacaaagcag ctttctgaga aaaatgatga attagaaaga gaaaatcagc atcttcttga
     3421 ggaaaataca agactagacc atacgttaaa aacaaccaca aatcgctatt gcacattgtt
     3481 ggaaagtgat gaatggacga tcaaacatag actaggacga cgtaagaaaa aaacatcgaa
     3541 aaaaatacaa gaaaaagagc tttctatatg tattgatgag aaaatatggg atgcagaaac
     3601 aaaaatatta aaaatcatcg gatggggaat cgctaattcg gatcgccagc cattgtccta
     3661 taagttatca gctgaccaat cgccattttt cgaagcaatt cctgtttcac gagatgaagt
     3721 caatcaagca gaacagctcg caaaaggaac agaagcggga tttgaattac gaatcctttg
     3781 cgagcaagaa cgttcattct tagtggaagc agtagctcaa aatggtcaat catggatcat
     3841 tgaaatgtaa ataatgatta acttataaag ataaggagta aacgaatcgt gcaaaaaaaa
     3901 gaaattgccg tatttatcga tcaaatcact cgtgaacggg ccactggcga tttgcttatt
     3961 gtgggctggg caattgatga agtgaccaaa gaaatcccta cgataaaggt agaaaaagaa
     4021 aatgtgattg ctgaagcaac acatgtcgta agattggata tcaatcattt atataatctt
     4081 gatgttaaga cccaaagcgg ttttaagata cgtttatccg ggaaaatgag aggaaaagcg
     4141 atcttagatt ttcaaacggc aaaacatcaa aatggcatag ctgtgaaact aaatggtaaa
     4201 tacccttatg atgacggcat tgaatcttca tgggaaagaa aaaaaagatt actgaaaaaa
     4261 gggataaatt atgcaaggac tcatggcgta aaaaaaacaa tccgccgggt caaactggaa
     4321 ttgaaaccag gatcgatcga ctatgcagag tggatcagtc gtcacgagaa acctgatctg
     4381 aaagagcaaa ggaaagaagc acaagggttt gcataccgtc cattgatttc catacttatg
     4441 cctgtctata acgttgaaat caaatggctc gaaaaatgca ttgattcggt attggatcaa
     4501 acgtatgatc actgggaact atgtatcagt gatgatgctt ctactgatcc agctatccga
     4561 aagtgtctgg aatcctatca agcaaaggat gatagaatca aagttgtttt ccgacaagaa
     4621 aatggacata tcagtctggc aactaattct gcgttggaaa tggcagaagg agaatttata
     4681 gcgctcttag ataatgatga tgaattaccg ccatttgcat tatatgaagt ggcaaaagtg
     4741 ctaaacatac atccagaact ggatttgatc tacagtgacg aagataaaat cgatgcagat
     4801 ggcaatcgct ttgatccgca cttcaaagca gactggtctc ccgatacatt gatgggaaat
     4861 aattatatct ctcacttagg cgtatatcga acaagtattg tgaaaaagct tggcggtttc
     4921 cgtaaaggct acgaaggctc tcaagattat gatttggtcc ttcgtgtgac agaacaaatc
     4981 cctgcagatc atatttacca tattgaccga gtcttgtatc attggcggac gatcccagga
     5041 tcaaccgcaa gtaatggtga agccaaaagt tatatctatg attctggagt gaaagcattg
     5101 acagatgccc tgtctagaag gaatatcaaa ggaagcgtac gtcctggcag aatttctgga
     5161 ttttatgaga ttgcttatga cgtcttgcaa gaggatttgg tcagcgtgat cattccaacg
     5221 aagaatggct atgaagatct aaaaacttgt gtggattcga ttatcgaaaa aacgtcttat
     5281 ccaaattatg aaatcattat tgcagataat ggaagtacag atcctaaaat gcaggaatta
     5341 tttgcagaat acaagcatca gctgaaagac cgatttatcg ttgaattaat tgacattcca
     5401 ttcaattatt cacgtatcaa caatctggca gcagaaaaag caaacggcaa atacttttta
     5461 ttcttgaata acgatacaga agtgattgaa cctgactgga tgacagcgat ggtttcttat
     5521 gcacagtttg atcgaatcgg ctgtgtagga gcaaaactgt tttatccaga tgatacaacg
     5581 cagcatgcag gagtattatt aggaatcggt ggtgttgcag gacatgcatt gaataactat
     5641 gatcgaacac attgtggtta tttcggccga ttggtcattg acgtcaatta cttagcagtc
     5701 actgcagctt gtatgatggt caaggcagct gacttcaatg ctgtcaatgg atttgatgaa
     5761 acattagaag tagcattcaa tgatgttgac ttgtgtttga aagtttatga actgggtcgt
     5821 tacaatgtct atgcacatca agcagaattg tatcatttcg aatctaaatc aagaggttat
     5881 gaagatacac cagaaaaaca aagacgtttt gccggggaaa taaaaaaaat gcaagataag
     5941 tggccttctt atattgctca tgacccattt tataacgata atctaactaa agaaggaatc
     6001 ggcgattttt cattgagacc tgattgatta aaagaactgt attttcattt ttattgatga
     6061 aaatacagtt tttttagtat atgaaaattg taacttgtga ccgaagagat gataggaaga
     6121 acacccattc agtaggaaga atgtgatacg atttttgtcc aactctctgt taggcagaaa
     6181 tatacatata aacatacaat agtcaccttt tctagtttct tttaatttat tttacaattt
     6241 ggttattcac taggttttta aactttgcta tggtaagatg atagaggcat tattttatgg
     6301 ttaggagtgt atatatgaat aaaaatgggg agtggaatgc ggcacgtagg atattcatta
     6361 tcatcatgga tgtacttgta ttgaatgtgt cgatctatct tagctttttg ctgaagttcc
     6421 aaggagaagt cccagcaaga aacttagaga cctttcagca ttcagcagtt tttatttcca
     6481 ttatctttat tgcgttgaat attttgttag gagcttatgt attctatagc cgagtgatca
     6541 gtgatatcgt cttcattact gttattggac aggtgctgat agcattgggg atcatggtag
     6601 ttacttttgc tggacgttgg tttgcatttc cgcgtggcgt catcgtgctc tcgtttatac
     6661 ttggcacgat attacttagc gtttatcgga tagttgttta taaactatac ttaagagtca
     6721 gtcgtgataa gaaagtcctt atcgtaggtt tggagaaaga tgtcgcacca gctatccaaa
     6781 actttcaatc taagaaaaac aacaaacata aagttgaagc agtagtgatc gacaagtatt
     6841 acgaaaacac aaaaaaattg attgatgata tcgatattgt ctacttggct tctaaaatcc
     6901 cagaagacga aaaaatcaat atttatcaat tagtaactaa aaaagagaag aagctatttt
     6961 taaatacaac ttttgaaaat ttaacgatga tcaatccgaa catcatgaat ttcgaagatg
     7021 aaagtatcat tgaagcttcc ggtttcaaaa ttcagccgga atatgaatta ttcaaacgtc
     7081 tttttgatat catcgtttcg cttattttac tgattcttgc ttcacctttt atgctaatca
     7141 cagcgatttt ggtaaaaaca acttcacctg gaccaattat ttataaacaa gtacgtatta
     7201 cgaaaaatca aaaggaattt tcaatctata aatttcgttc catgagtgta acagctgaag
     7261 caaaatcagg accggtcttg gcaaagagca atgatgcacg tgtgacacca gtaggcaaat
     7321 ttatccgtgc cgtacgtttt gacgaattac ctcaaatctt taatgtattg aaaggcgata
     7381 tgtcgatcgt cggaccacgt ccagaaagac catttttcgt tgatcagttc aatgaagaaa
     7441 atccttatta ttatttaaga cacaatgtac gtgcagggat taccggatat gcacaagtat
     7501 acggaaaata tgtatcagat tataatagta aactacgttt tgatttgttg tatatcaaaa
     7561 agtattcctt actattagat ttgaagattt tacttcaaac aatcaaaatc ttatttgata
     7621 agatgtcctc acaaggacta gatgaagatg aaaatatccg ttcgttagca gaaatcgact
     7681 tttcacaaga gaaaatttat cgctagatgg gaaaaatttt gagcaaagaa gtaggagaga
     7741 acattggaaa ataaaaatat aagtatgctg ctttctttat atgataaaga aaaaccagag
     7801 tatttaaagg aagcattaac tagtattttt gagcaaacag taatgccaaa agaaattgta
     7861 ttagtttatg acggccctat aaatgaaaaa cttcaagtag ttgtcactta tttccaacaa
     7921 aaagatcctc acttgtttac agttgtaaaa ttagaaaaaa atcaaggatt ggggattgct
     7981 ttagcaattg gattagaaca tacgaaaaat cgcttagtag ccagaatgga tacagatgat
     8041 atcatggaac cccaacgatt agaaaaacaa ttagagatct tccaaaaaga tccagaaata
     8101 gcgattgttg ggagtaatat tgaggaattt actggcacgc ttagcaatgt tatcggaaga
     8161 aggattgtac ctgaatataa tgatgaaatc cgtgtgtttt cgaaaagaag aaatcccttt
     8221 aatcatatga cagtcatgtt tgataaaaat gctattttag aagtgggaaa ctatcgccca
     8281 ttaattggat ttgaagatta ttatttgtgg gtaagactgt tgaaggcggg atataaaggg
     8341 tataatatcc aagagattct agtccatgct agagcaggtg ctgacatgta tgctagacgt
     8401 ggaggaagta aatatctttt accaggaatt aaaggccgat atcgcgtatg gaaagatggt
     8461 ctaggatcac taaaagattt tctgatagtt atttgcggac atcttgtaat tagtttatta
     8521 ccgaataaaa ttaggggaaa agtatatgaa tcaaaactta gaaaaacaaa ctaaactttc
     8581 tataatcata cctttttaca atgcaaaaaa tactttaaaa agagctgtag acagcgtctt
     8641 aacgcaaggt tatcccaata ttgaaatctt gttaattgat gatggatcta cagatggtag
     8701 tagtgacatt ggtgacgaaa ttgctaatct agagagtaaa gtagcatgtt atcacttgga
     8761 aaacgctggt ccatcagttg ctaggaattg tgggataaaa gaagcaactg gaaatttggt
     8821 aggattttta gatagtgacg attatttttt acctgattgt tttaataatg ttttgaaaga
     8881 ctaccatagg aattaccccg atatcattgc ttttggatta agtaaaggaa aaaatataga
     8941 aaatgcaaat ttatttgttc ccgaaaagaa gattggttgt tcaagtgaag aagcaattga
     9001 gcaaatgttt agaagtaagg cagtggattt ttacgtatgg aataaatttt ttaaaaggga
     9061 attattcaat catatagttt ttccagaaaa taaattatat gaggatatgg ttcctatgta
     9121 tgaagctttt agagcggcta gtaaaattga tattttgcca ttttcaggta ttttttatta
     9181 tcaaaataat gatagcatcg tttatcagtc ttttaattca aaacagtatg ataatatttt
     9241 gcaaagaaaa atattagttg atgaagtaaa gaaagattat cctcgactta ttaatttggc
     9301 caatgctcga ttagtagacg gatacctttc aacagggttt aaaattactg gcaagaatca
     9361 aaatcagaaa gaaaagcaaa aatattataa tcagtctaaa agagaaataa aaagtatata
     9421 ttcaaaaata agaagtaaca atgagatatc aattgctaaa aaattagctt tatttttata
     9481 cttaattaat cctaaaactt attttatttt atataaaaaa gttctaaaaa aataaagttt
     9541 ttttcgatat gttatttttt atgtttatta acttcggaag actaaaattg ttactggtaa
     9601 tgatacattt gtaaaaataa aaaagatgat ttttaggaag tgaagagagt gcataaaatt
     9661 agtgttatag tacccgcata taacgtagaa gactatttag aaaactgctt agaatctatt
     9721 tccaaccaga cacattcaaa tattgaaata atagtagtca atgatggttc cccggatcga
     9781 agtggggaaa ttgcagaaga atataaaaag aaagatatgc gattaaaagt gatacatcaa
     9841 gtgaatggtg gtttaagtgc ggctaggaat tctggtcttg attctgcaac aggagatttt
     9901 gtgtgcttta ttgacagcga tgattggata gaaccagact atcttgagtt actatatttt
     9961 ggcacgcaaa cttatggagc agatatctcg gtgctaaaaa taaaaaagat ttcaagttta
    10021 gaacaactaa aagaacatac aattgctgag agaaaatggg aaatatttga tagagaacaa
    10081 gcaatgaaaa acttatttat aaataataaa attggctatt ctgcaaataa taaattattc
    10141 aatagaaatt tatttgataa tataagattc ccactgggta aattaatgga agataaggct
    10201 actacttatt tgctgatcga tcattccgaa aaagttgctg tcaattcatc tgctaaatat
    10261 cactattacc aaagccctaa aagtatactg agaggaagct tcaatcctag aatttttgat
    10321 tcttttgaag tccatgaaga tatactaata ttcatagata agttttatcc ggaattatca
    10381 attaatgtta gaactcgcta tgtctatgaa gcaataagga tgatgatgac aatgattaaa
    10441 aataactata ccaataaaga agattattta cgttctataa atattttaca acgctttgaa
    10501 aaagaagtga aaattgatcc cgacttttca ccaaaattaa aaaaattagt aaagttttta
    10561 ttaataaata aaaacttgcc ttactatatg tcaagtagta agatagcaag taaattcttg
    10621 attaagatag aatctgtgag gtaagagatg aagaatataa aaaaattttt ttcaaggaat
    10681 attttcccgg tttttattaa aatattacct attcaaaaaa atttaattgt attttcaagt
    10741 tttggcgggc gtaactattc tggaaatcca agagttattt cagagaaaat tcatgaaaaa
    10801 aaattgaatt acagaattat ttggttaatc aaaaaagaag cgattataac tgatttacca
    10861 gattatatta aaagaattga ctccgattct tttttagctg ccttttattt atatacagct
    10921 aagtattgga tagacgatag tcggaaaacg attaagtatg caaaaaggaa aaaacaactt
    10981 tattttcaaa catggcacgg aacgccttta aaaaaaattg aatttgatgc aaaagataag
    11041 ttacctaaac gttacctaag ctatgcgaaa aaagatagtg agtcaattac atatttatta
    11101 tctggtaatc gctatagttc taagaagtat gtttcagcat tcaatatcgt tccttctaaa
    11161 atattagaag taggaactcc tagaaacgat gaattagcct ctagtaaaga gcaagtgttt
    11221 gacttgaaaa agaaacaaat caatgtctta tttgctccaa cttttcgaaa taatattgag
    11281 gacaacggaa ttacgcaact agaatggtta ggtgtggata acttacgtga attttttaaa
    11341 aagcaacaac aagaattaaa ttttatgact aaatttcatc ctaatgttca tagtaaatta
    11401 gcaactgatt ctaaaagtat agaatatatg aaaaaacatc aaattacttt aattaatgat
    11461 gggattcctc ttgaaatgct ttttgaagag atagatgttt taatcacaga ttattcatct
    11521 atttttttcg attttgcgct aacaaaaaaa ccaattattc tttttaacta tgatgaaaaa
    11581 gaatatagct tagaaagagg tttttatata cagttaagtg agttaccaat tataagcgta
    11641 caagatagtt atggccttgt tgatgttttt aaaaaccaac aagaaaagct tttgaaaagt
    11701 tctcaagagt tacttgatta tattggaaat tatgaaacag gagcaagtac agaaaaggtt
    11761 cttgagttga tagagaggga tataaagtga aaaaaacagt aaaagatata ttttataatg
    11821 cgatatatca agtctttttg attgttttac ccttacttac tatacctata cttagtcgta
    11881 gaattggttc aactggttta gggatttatg ggtatgtttt ctcaatatca cagtttttaa
    11941 tgactgtcat tgctgtggga atgaatcctt ttcgtattcg aaatatcgct aaatcaagga
    12001 aagataaaaa agcactatct ttacaattct ggaatattta ctttattcaa tttttaatag
    12061 gcttgagtgt ttcctttctc tatatagcct atatttattt ttttgatgta aagtataaaa
    12121 atttatactt aattcaattg atatttattg tagggctaac attagatatt tcttggtttt
    12181 ttcaaggaat tgaagaattt tcgaaagtgg ttattagaaa tacagttatc aaattatcat
    12241 cggtattgtt aataatcatt tttgtttcaa ctaaagatga tttgtggatt tacgtgttca
    12301 ttacttcaat tactaacttt ttaggaagtt tagttttctg gttaagtatc cacggaaaag
    12361 taggtaaacc aatctttaac tctaatgttt ttaaacagtt gtggaaacca gcttttatta
    12421 ttttgactcc tcagttgttt atgcaagtgt acacaacttt agacaaaacg atagttgggt
    12481 attttgtgga tccaacggaa ttatcttatt atgatcagtc tcaaaaaatt gctcgtatta
    12541 tattggcagt cttaacatca attactattg ttatgttgcc taaaatatct aaagcacagg
    12601 cagaggggaa atcagaaaat attttagttt acacaaaaaa atcttttgat tacacgatta
    12661 tcattgcatt aattcttttt agtgtggtgt ttatcaatac aaaagaattt gttccatggt
    12721 tttttgggga gaatttcaaa ccgatgacaa taaacatgct tatttcttgt ctaattatag
    12781 ttgttagtcc aattggtgga gtttttgcta accaatttgc aattgctata gaaaaagata
    12841 aggagtatgc ttatccaatg atcattggtg cgattgtaag tattattgga aatgtagctt
    12901 ttgtgcctac ttatggcgct gtagcggcta cgatcgtact cgtggtagta gaattattag
    12961 tctttttctt tagagtattt tttgtacgaa aagaaataaa aatatcctat ttctttggga
    13021 agaacgttat cttatttttt atagtcaatc ttactttgac tacttgggcc tattactttc
    13081 ttccacaatt attctcttct tcatttttag atatggcaat taaatcaata atgattttca
    13141 ttatttatct tccgtttgtt tattttcttt ttccagatat acgaaatgaa ataagaaaga
    13201 ttactcgaaa ataaaataat gttgtaaaaa agtagttctt tgtcaaatcg ggctgataag
    13261 gtcatttatg aacaacaaag ttagtaagag ttactagctt ttaatgcata gctgattaac
    13321 ctgttgatta gaaaaatcca caagcgcata ttggtaaaac tgcgaaaccc ataagcaaat
    13381 cgtttcaatg ttttgatatg tgtgcgaaga ttctctaatt ttgttattag aatacttttt
    13441 cgaaaatgct agttaaaagc ctttttcaga tatgaaaaag gctttttgag atagtgaagt
    13501 ttcgagggaa cttctttggt cgtttctcga agtagctagc tgtttcttgt gataattgct
    13561 aagcagcttt tgataaactg cttagcaatt ttaagttcat aagagattga gggtagacga
    13621 tcaactactt cactttctgt taaatagcgc cattgaaaat tctgccattt cttgaatgtt
    13681 gtgtaatcca actcgtcatc tgattttaga agtaatttat acaaaggttt caattgtcga
    13741 tagtacttag cttgtgaagt gtctttttga ttcaactgct tcatcacacg ttttcgaaca
    13801 cgatcgaaaa acttgttcaa gtgttgtcca atgtgaaagc aatcaatgat gatttgggcg
    13861 tttggaaagg actctttgac taatgaaaaa taaggggcat tcatatttgt gacaatgtat
    13921 cgaaccccca tatgagcttt tcttgtaaaa cgcatgaaat aagcaatcaa atcttttttt
    13981 ctccggctgg acaaaatgtc aaagagcttc cctgtctctc tattcataca agaaaaggag
    14041 aactttccat gggaaattga aagagagcga aactcgtcga atagtaaaca atgaggtaaa
    14101 tagtctagca tctgtcgcag cattgccgat agagcagata atgtccgttg aaatgtcgtt
    14161 actgaaagat cacaacgttt cgtaagtgtc tttaacgctt gacgctcggt caactcttct
    14221 aatatcgtgt aatgaacttg tttcgaaata aaacatgaag gaacgacaag atacgtatga
    14281 gcagtaaaat attttccgca tgattggtag tggtaatgtt gttttctaag acgcaaatag
    14341 gtttatttat tcccactgcg atttaagata atcattgaaa tcttcttgcc gtttttcacg
    14401 agctgcttcg cagtttcttt acaaaataga caatgtctaa aagtgcgaac taatgtacct
    14461 tcgattacga tggctttctt gtccttataa aaagtttttt gaaaagaatt aatttcaata
    14521 tttttatctt taatagtgaa gtgctctttg atagaacgag aaatggatat acaaaatctt
    14581 cctttcagat tgatgtttta gacgactcta ttttatcgaa atttttgtat gtctgttttt
    14641 tttacaagaa aatctaggat cgacagaaaa ttctatcagt cctagaaatt atagagccat
    14701 ttttttacgt cttatccaga tatattgttc tttcattgtt taaaaaatat tatttatcac
    14761 tatttaaaga attaagttcg ttctttattt gagttgtaga gatctcaggt gttcttggta
    14821 aataaattac ttgtgcatct gttagttgtt caagttcatc aaattgtcca gcccaatcat
    14881 cgcccatcac gaaataatct gcatggtatt cttttatatc ttttactttt tgttcccaat
    14941 tttcttcagg aataactaaa tcaacgtagc gaatagcttc aagtaactgt tttctttttt
    15001 cataactaaa ataacatttt ttttgtttcg cattccaatt gaattcatct gtagaaaggg
    15061 caacaataag ataatctcca tattgttttg ctcgtttcag taaattgata tgcccgtagt
    15121 gaagcaaatc aaaggtaccg taagtaatta ctcttttcat ctttcacctc tcgaaattca
    15181 ttaatataca ttgttagttt agcatttttt tgttagaatt gaaagaacca gtttatccta
    15241 aaaaggataa gaaatgttta tgagaaatag gtggatggag gaaaaatgtt gaatgaaaaa
    15301 tttttaaaat atgtgaaagg ttggtatttt atttattttg gttttattct aatgttacga
    15361 gcaataggcc cgtatttact attacctact agatatgata ctttactttt ttggcctgct
    15421 ggaatagcgg gagttgtctt gatcattata gatgcaatta ttgcatttag agaaaaaaat
    15481 cttaaaaaat atgattggct attaattgct tttattggcg cgatgctagt aagcagttta
    15541 atgaatttaa aatatggata tagcgaaaat atcaagttaa tcatgtggca attaatcttt
    15601 ttctttatga tttatcagtt tggcaaagac tacagtagta actttttttt caaagtattt
    15661 acttggatac tttcattggt atggttttta gctaatttag tatcattata ctggtttgtc
    15721 attcaatatg gcataaaaat tccaataaaa tataagtatt acccagttcg tttagggtgg
    15781 ttaggcaacc gtttatttgg tgtatataca gatccaaatt ttggtgcggt tatatcatta
    15841 attgtcatca ttattgctat atattatttg gtcacttaca agcatttaaa tcttctattt
    15901 aaaatatttt ttgcaattaa tatttttatt caattctcgt ttattgcttt atcgggctca
    15961 cgcaccacat tagtttgttt attaatagca acttttgttt ttagtttctt tacaagttat
    16021 agtagtcgtt ttcttaaaac taatacttta aaaagatggc taactgcatt agtagtagga
    16081 ttgctaagta taattgcgat gtattatgta acagatataa ctgctcaagc atgggcacat
    16141 gttccgcata ttacagaaat aaaaaaagat atatctgatt catcaggaac aactagcagc
    16201 aataaagttg atttaaaacg ccctgacact gatggcgggg atgtttctaa tttaaggttt
    16261 ggactttgga aaagtgcaat tgaaatattc aagagtaagc cgatatccgg cggttctcca
    16321 ggatactata ttgaatacgc acatgataaa ctaccatata cattaatggg aaaagatact
    16381 ttaactgctc ataattttat tttcttagtt atggctgcta caggaggatt aggtctattg
    16441 acattgttaa ccttcttatt tatccaatgc tttaaaactt tgcgttattg tttcacacaa
    16501 ccaaatctag taaaagataa gcactttttt gctattttaa tgattcttac aatagcagtt
    16561 tcggcattat ttatcacaga actcattttg gttagtacga taggttcatt tattttttgg
    16621 ggatatctgg gttctatcca aaaaactata tctaaagaag aaggagtaac taattgaaac
    16681 tatttttagg tatataaagt agaaaagaaa actagttatc ccaacttcaa caaattttat
    16741 agtttttaca atataaaaat ggtaaactaa ctttattaag tatgagaatg cataattgga
    16801 gtgaatttga tggatactat attgattact ggtggagctg gttttatcgg ttcaacgcta
    16861 gcgaattatt tgggaaaaga aaacaaaatc gtagtagtcg acgatttatc aatgggaaaa
    16921 aaagaaaact tggatatgga gaaacaagtg actttcattg agggggatgt atcagatcct
    16981 caattgatgg aaagaatcat gaaacagtat cagtttgcct atatttttca tttagctgct
    17041 gtagctagtg tggcagattc tgtagaacgt cctctagaaa ctcatcgtgt aaattttgac
    17101 agtgcgcttt tattgcttga attggtacga aaatatcaat ctggtttaaa acgattggta
    17161 tttagttcat cagctgcagt ttatggcgat gaaccaacgt tgccaaaaaa agaagaatcg
    17221 gtcatccgtc ctttaacacc atatgccatc gataagtttg catcagaaca atatgttttg
    17281 gattactgtc atttatatga tgttccgact agtgctgtcc gattttttaa cgtttatggt
    17341 ccaaatcaaa atcctaactc tccatatagc ggagttattt cgattctagt ggaccgatac
    17401 aaaaaacaat tggcaggaga aaaaacagaa tttactttat ttggtgatgg tagccaatct
    17461 agagacttcg tttatataga agatgttata caagcacttt tacttgttgc taaggaagaa
    17521 aaagctttag gacagcaatt caatgtcggt acaggaaaaa gcactacgct acttgaattg
    17581 attcattcaa ttgatcaaat cttaggaaca gagctagcgc ttaaatatga agcggagcgt
    17641 tcaggggata ttcgtgattc tttagcggat atttcaaaga tccgttcttt aggttatcaa
    17701 cccaaatttg atatattgaa cggaatggaa cgttatttaa agacagaaat cgattgaaac
    17761 aaaaaaccag catcctgctg gtttttttgt ctcgacttag ctttttaaat taacaccttc
    17821 catcagttcg taaatctgat ttcttaaatc agtggccggc aatttgatgt ttttatcaga
    17881 ttggatatta ctttccatga cgattgcatc ttttgtgtct tttttcatcg ccgctactgc
    17941 atggaatcga ttgatatttc cctgagcaag gatataatca tttccactgt aaacaccgcc
    18001 gctgtaagga tgtttatcac cattattttg ccacaatgag aaaagtagtt cttttggtat
    18061 aatatcgcca gacagaacac tggtaaagaa tttgttcaag tcataaacag acatacttat
    18121 atttcctgtg cctaattcat ttcggatgtc tgtttcaggc tcgaccaatg cttttgaata
    18181 atcgtcagtt gcagacattt ggtaagatac agcatgctga ggggaatttt ttacattttc
    18241 ataaaaatct gtatgttcta gatggagtgg ccgaatgatt tcttttttta aaagagtttc
    18301 ataaggctga ttcattagtt tgatcaatac ccctgtaagc aatgtataat ttaatggttc
    18361 ataatgatac gtatcataac cagtaaattt caaatgatga agggcaaact gaatgatctc
    18421 actatctgac ataggttttt ttggagaagc ggttcgatga agaccagagc gcatgtaaag
    18481 catatttttg attgagattt gctgacttcc aggaatctga ggataaaatt cagatagctt
    18541 tgtgtcaaaa gttatcttgc cagattgaat ttgttttagg ataagtaaag cagtcatcgc
    18601 tttttggatc gaaccgattt gatagtaaag agaaggagaa ttcgattctt ttatgcgtag
    18661 atttgcgtac ccatatcctt tttctaatat cactcgatta tttttgcgta cataaatcga
    18721 accgatataa tctgattttt gcagtaattg atcaattttg ctggcaagca tctgctcatt
    18781 agatgttaaa ttggaagcaa gttgtgcggg ttccgtttta taaatttgtg gttgaggttg
    18841 ttttgttaat tgccatcctg taatgatgcc tgttgaaaag aagctgacag ccagcaacaa
    18901 aactgcgaga aaagaaagag agatctgctg ttttttttga tgttttcctt ttgccatatt
    18961 aaatcctttc tatccatttt taactatttt tcattgtaat cctcaaaaag agcatttgcc
    19021 acttacaatt ttgacataat atttggtaaa ataattcacg gcagtagaaa tttcatgtat
    19081 aataaacaga gttacgaaga tgatagtaag gaggagttgt tttgtcagga aacaaacaac
    19141 acccaagcaa agacaaaaaa gaagccagta aggcagctac agcagatata atcgacaagc
    19201 ggagaaatct gcgtaaaaaa gaagataaga tcgtgaggaa gatcatttta gtgatcgctc
    19261 ttacattatt gattattggc ggatttctcg ggtttaccgt atatcgttat gtagatagcg
    19321 ggttgaagcc tttagataaa tcggacgacc aattagtcca agtggaaatc ccaaacggct
    19381 cttctaataa gcagattggc gaaattttgg agaaagacaa tattattaaa agtgggattg
    19441 ttttcaatta ttatacaaaa tttaaaaact taactggctt tcaagctggt tattatcagt
    19501 tagcgcctaa tatgactctt gatgagattg gcaagcagtt gcaagaaggc ggcacatctg
    19561 agccaacaaa agttgcagat gggaaaattg ccattccaga aggctacgac atcgatcaga
    19621 ttgctgagcg ggtagcgaag gtaacaggta aagacaagaa agaattttta gatttagtaa
    19681 atgatgagac tttctttaac gagttgtatc aaaaattccc agaattgttg gaaagtgcct
    19741 ctaaagctga gaacacaaaa taccgtttgg aaggctactt attcccagct acttatgatt
    19801 actacacgag tacttcgctt aaggatcttg tgattgagat ggtgaacaag acaaatacgg
    19861 tcatgcaaaa ctattattca gctatcaaac agaaaaattt gactgtacaa gaagttttaa
    19921 ctttggcttc tctagttgaa aaagaaggcg taaaagaaaa tgatcgtaaa aatattgcac
    19981 aagtcttctt taaccgaatc aaggcaaata tgccacttca gtcagatatc tctgttttat
    20041 atgcattagg agaacataaa gaattggtga cgtatgaaga tacagctgta gattcaccat
    20101 acaatttgta taccaatacc ggctatgggc ctggtccttt tgacaatcca agcgaaaagg
    20161 caatcaaggc agtattagaa ccagcagaaa atgactatta ttatttcgta gcagatacga
    20221 gcactggaaa tgtttatttc gctaaaacgt atgaagaaca tatggaacta gtgcaaaaat
    20281 atgtaaataa ttcttagaaa aacaggggct agtcattgat catttttaga aaaacattta
    20341 cattttaaga aaagcgtggt aatctttttt ggactatatt cctcaaaaga ttaccttttg
    20401 cggtatttta tcgaaaaaag gagacgttac acatggtaga gaaagtttat ccaatgactc
    20461 tagaaggtaa agaaaaatta gaaaaagaat tagaagaact aaaaacagtt aaacgcggag
    20521 aaatcattga acgaatcaaa atcgctcgcg gtttcggaga tctttccgaa aactccgaat
    20581 acgaatcagc taaagatgaa caagcatttg ttgaaggaag aatcacaaca attgaaaata
    20641 tgatccgttt tgcacaaatc atcgataatg acggcgtaga tgcagatgag gtatcgatcg
    20701 gtaaaacagt tacgttcatc gagttgcctg atggagatga agaagagtac acgattgtcg
    20761 gaagtgctga agcagacccg ttttctggaa agatttccaa tgattctcct atcgcgcaag
    20821 cattgattgg caaacgtaaa aatgatgaag taaccattgc tacaccaggt ggcgatatgt
    20881 tagttaaaat cgtcaaagta gaacaagcgt agtctgactg aaagatctag agagttcatc
    20941 ttactgatga cgcactctag atcttttctc tttgagtatt gcaggtttca ctgaacgatc
    21001 ttacatctaa agtcctatag ccaacagtca aaaaaatagg tatgatgaaa tgagaatgtg
    21061 tcaggaggga gaaaaagcga tgaatagttc ttggcgtttt tttgtggtag tcgaagcact
    21121 gctgctgtta tttgctgttt ggcaaatcgt aaacaatact ggacttttgc ttttagtaat
    21181 attcggtatt ttcaatatat atctagctat gcgcaaatat cctcgtacta aatttcaaaa
    21241 ttttcaattg atcttaggga gcttggtcat tttttttagc ttagtcaaca gtcctgcttt
    21301 atggatgatg gttgtattgg ccgttttatt tatcgggctg aaaggtgtag agatttcagg
    21361 aatagatttg acaaaaaatg ctttttggcg aaaaaaacag atcatgatgg tccaaacaga
    21421 gcaattaaaa acacataata atgagcgtaa aagacagcaa ttatttggta accaacgtat
    21481 tggaaacgac gtctatgaat gggatgatat caacattgcc atcatttctg gtgatactat
    21541 catcgatttg ggtaatacac ttttgccaaa agatgataat attgtgattg taagaaaagg
    21601 gataggcaga acacggatct tagtacccct gggagtggct attcgtttag agcatgcgac
    21661 attagtagga aatgtcttgt ttgaagaaga gcagttttcc ttaaaaaacg aacagatcaa
    21721 aatctgcagc agtgattatg atgaaaatcc tcgcagattg aagatcatta ccaatacctt
    21781 ggttggagat gtcgaggtga tacgaatatg atgggaagaa tatccaaagc aatgctagct
    21841 gtttattcgg ggattgcggc tttccttatt attctatttt cacttttcac ttatttttat
    21901 gccagtaacc aaagtcattg gtggggagaa ttgctgcgtg cgcgtttatt atacgttccg
    21961 cttatcttcc atttgatggc aatttcatta ggtgtaggat tgatcgtatt tctattgtta
    22021 tcacttattc aaaaggcaaa atacgggaaa atcgaagaaa agcttcgtgc actttcttct
    22081 ggcaattatg aatccaaact tttgcatcag ccgatcccaa gcgcgtcgga tgatctgtac
    22141 atcaaagata ttgatatgga aattgctaaa ataaaagaaa aaatgatcga agtatccagt
    22201 gaattacaga ttatgactag ccgtcctcaa tatgtagatg gacaaaccaa agaagagatt
    22261 ttagaattag aaaggcatcg attagctcgt gagcttcatg attcagtttc acagcaatta
    22321 tttgcagcga tgatgatgat gtcggcattg acggagcaag cagaaaaaag tgagacacca
    22381 gaaatgttcc gtaagcagtt gaaaatggtg gcagagatca tcaacgcttc ccagtctgag
    22441 atgcgtgcgc tgcttcttca tctgcgtcca gtcaatttag aagaaaaaag tttaaaacaa
    22501 ggcattgagc agttattgaa ggaattgcag aataaaatcc agatttcgct aaaatgggat
    22561 gtagaagatg taaaattaac tagttccatt gaggatcact tgttccgaat cgttcaagaa
    22621 ttgttatcaa acacattaag acatgctaag gctaatgaat tagaagtcta tttgcataaa
    22681 atagataaca atcttttatt acgtatcatt gacgacggga caggatttaa tatgaatgaa
    22741 accaaaacgg gaagttatgg attgaacaat atcaaagaac gagtagctgg tattggtgga
    22801 acagtaaaaa tcattagttt taaagggcaa ggtacgagcg tggagatcaa ggtccctttg
    22861 atgaaggagg catagataaa gatgataaaa gttttattag tagatgacca tgaaatggta
    22921 cgcttaggcg tctcttctta tttatctatc caagaagaca ttgaagtgat tggagaagct
    22981 gaaaatggac gtcaaggcta tgaaaaggcg atggcacttc gaccagatgt cattttaatg
    23041 gatctagtca tggaagaaat ggatggcatc gaatcaacaa aagcaatctt aaaagattgt
    23101 ccaaaagcca aaatcattat cgtcacaagt tttattgatg atgaaaaagt ttatcctgca
    23161 attgaagcag gagcagcagg atatttgttg aagacgtcta ccgcacatga aatagctgat
    23221 gctataaggg ctacgcaacg cggcgagcga gtattggaac ctgaagtgac aacaaaaatg
    23281 atggaaaaaa tgagtcggcg aaatgatcca gtattgcatg aagaattaac gaatcgagaa
    23341 aatgaaattt tgatgctgat ttctgaaggg aaaagtaatc aggaaatcgc ggatgaattg
    23401 tttatcacac tgaaaacagt taaaacgcat gtgtcgaata tattagctaa gttagaggta
    23461 gaagaccgaa ctcaagcagc tatctatgcg tttaaacatg gtttggtgaa ataaaaacga
    23521 tgataaagag gataatcaaa agctgagaaa ataactatta tttttcttgg cttttttaca
    23581 ataatgatgc ttgcttttgt ttttggaaag gctttgttat actgagaaaa gaagatacta
    23641 aaggaggaaa atggtgaaac aaaattttgc aattgtaggc cttggacgat ttggcggaag
    23701 catctgccgt acactgatcg aagctggaca agaagtactg gctattgaca gtaatgaaga
    23761 tcgagtcaat gaatatatga atatagccac tcatgctgtt gtggcaaatg cacaggatga
    23821 gatgacactt cgttcattag gtataagaaa tttcgatcat gtaattgtcg ctattggaga
    23881 agatatccaa gccagtatct tagttactct gatggtaaag gaaatgggcg taccgaatat
    23941 tttagcaaaa gcccaaaatg agtaccatgc ccgtgtacta gagaagatcg gagcagatcg
    24001 tgtcgtacac cctgagcgag acatggggat acggattgca cataacttag tatcaaagaa
    24061 tattctagac tacttagagc tgtcagataa atattcttta gcagaaatcc gagtctccaa
    24121 tcctaaattt ttcaacaaaa cattagctga attaaatttc aggcaacgtt ttgacttaac
    24181 agtagtcgcc atacgaagag tagatcaaac ggttatcgct tctcctgcag cagatgaata
    24241 tgttcgcgaa aatgataatc tactggtgat tggagagaca ggcgatgtgg atattctaga
    24301 cgataagatg aatcaataga aagaaaagag aaagtaggtt gttgggatgg aattaacggt
    24361 aacgccaaaa gcacaaaagt ggtttgactc agaaattgat ctgccagaaa cttacggaat
    24421 acgttttttt ggaaaagtct acggcaaaac agaggttcat gatggttttt cgattggaat
    24481 gtcagttgaa cagccagaac atcctgtaaa gaaagtggaa atggatggga cacttttttt
    24541 tatcgaggaa gcagatgaat ggttctttaa aggatatgat ttacttgttg attatgatcc
    24601 caacctggag gagccaacct atcactttaa aaaacaataa aaaaagagag ggtgacacaa
    24661 gtttt
//
LOCUS       DAXLPY010000038        24272 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.038, whole genome shotgun sequence.
ACCESSION   DAXLPY010000038 DAXLPY010000000
VERSION     DAXLPY010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.038"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..572
                     /locus_tag="ACF3UF_001657"
     CDS             <1..572
                     /locus_tag="ACF3UF_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFD3671770.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="ACF3UF_001658"
     CDS             576..1217
                     /locus_tag="ACF3UF_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671771.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDFIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="ACF3UF_001659"
     CDS             1214..2131
                     /locus_tag="ACF3UF_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3671772.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="ACF3UF_001660"
     CDS             2128..2799
                     /locus_tag="ACF3UF_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671773.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="ACF3UF_001661"
     CDS             complement(3340..3828)
                     /locus_tag="ACF3UF_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFD3671774.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="ACF3UF_001662"
     CDS             complement(4029..4295)
                     /locus_tag="ACF3UF_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFD3671775.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="ACF3UF_001663"
     CDS             complement(4295..4558)
                     /locus_tag="ACF3UF_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3671776.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5079..5219
                     /locus_tag="ACF3UF_001664"
                     /pseudo
     CDS             5079..5219
                     /locus_tag="ACF3UF_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(5361..7184)
                     /locus_tag="ACF3UF_001665"
     CDS             complement(5361..7184)
                     /locus_tag="ACF3UF_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3671777.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="ACF3UF_001666"
     CDS             complement(7782..10487)
                     /locus_tag="ACF3UF_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFD3671778.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="ACF3UF_001667"
     CDS             complement(10793..11740)
                     /locus_tag="ACF3UF_001667"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFD3671779.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="ACF3UF_001668"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="ACF3UF_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFD3671780.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="ACF3UF_001669"
     CDS             complement(12375..12737)
                     /locus_tag="ACF3UF_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFD3671781.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /gene="alr"
                     /locus_tag="ACF3UF_001670"
     CDS             complement(12748..13869)
                     /gene="alr"
                     /locus_tag="ACF3UF_001670"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFD3671782.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /gene="acpS"
                     /locus_tag="ACF3UF_001671"
     CDS             complement(13885..14235)
                     /gene="acpS"
                     /locus_tag="ACF3UF_001671"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFD3671783.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="ACF3UF_001672"
     CDS             complement(14365..15876)
                     /locus_tag="ACF3UF_001672"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD3671784.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /gene="murF"
                     /locus_tag="ACF3UF_001673"
     CDS             complement(16198..17550)
                     /gene="murF"
                     /locus_tag="ACF3UF_001673"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFD3671785.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="ACF3UF_001674"
     CDS             complement(17703..18779)
                     /locus_tag="ACF3UF_001674"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFD3671786.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="ACF3UF_001675"
     CDS             18975..20720
                     /locus_tag="ACF3UF_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFD3671787.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="ACF3UF_001676"
     CDS             complement(21000..21437)
                     /locus_tag="ACF3UF_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFD3671788.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="ACF3UF_001677"
     CDS             complement(21421..22794)
                     /locus_tag="ACF3UF_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671789.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="ACF3UF_001678"
     CDS             complement(23116..23604)
                     /locus_tag="ACF3UF_001678"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3671790.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="ACF3UF_001679"
     CDS             complement(23626..24228)
                     /locus_tag="ACF3UF_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFD3671791.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6960 a         5166 c         4485 g         7661 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgattttatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agcccaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgcc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcgt aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctt caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa acttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc acggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc tt
//
LOCUS       DAXLPY010000039        23784 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.039, whole genome shotgun sequence.
ACCESSION   DAXLPY010000039 DAXLPY010000000
VERSION     DAXLPY010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.039"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..246)
                     /locus_tag="ACF3UF_001680"
     CDS             complement(<1..246)
                     /locus_tag="ACF3UF_001680"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3671792.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEE"
     gene            complement(248..2263)
                     /locus_tag="ACF3UF_001681"
     CDS             complement(248..2263)
                     /locus_tag="ACF3UF_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3671793.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(2442..2747)
                     /locus_tag="ACF3UF_001682"
     CDS             complement(2442..2747)
                     /locus_tag="ACF3UF_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFD3671794.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(2836..3867)
                     /locus_tag="ACF3UF_001683"
     CDS             complement(2836..3867)
                     /locus_tag="ACF3UF_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3671795.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            4074..4949
                     /locus_tag="ACF3UF_001684"
     CDS             4074..4949
                     /locus_tag="ACF3UF_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3671796.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(5101..5943)
                     /locus_tag="ACF3UF_001685"
     CDS             complement(5101..5943)
                     /locus_tag="ACF3UF_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3671797.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(6035..7912)
                     /locus_tag="ACF3UF_001686"
     CDS             complement(6035..7912)
                     /locus_tag="ACF3UF_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3671798.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(7909..9330)
                     /locus_tag="ACF3UF_001687"
     CDS             complement(7909..9330)
                     /locus_tag="ACF3UF_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3671799.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(9333..12722)
                     /locus_tag="ACF3UF_001688"
     CDS             complement(9333..12722)
                     /locus_tag="ACF3UF_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3671800.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            12979..14370
                     /locus_tag="ACF3UF_001689"
     CDS             12979..14370
                     /locus_tag="ACF3UF_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3671801.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(14443..15090)
                     /locus_tag="ACF3UF_001690"
     CDS             complement(14443..15090)
                     /locus_tag="ACF3UF_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3671802.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(15098..15784)
                     /locus_tag="ACF3UF_001691"
     CDS             complement(15098..15784)
                     /locus_tag="ACF3UF_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671803.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(15790..16863)
                     /locus_tag="ACF3UF_001692"
     CDS             complement(15790..16863)
                     /locus_tag="ACF3UF_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671804.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            17085..17759
                     /locus_tag="ACF3UF_001693"
     CDS             17085..17759
                     /locus_tag="ACF3UF_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3671805.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            17764..19104
                     /locus_tag="ACF3UF_001694"
     CDS             17764..19104
                     /locus_tag="ACF3UF_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFD3671806.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(19253..20239)
                     /locus_tag="ACF3UF_001695"
     CDS             complement(19253..20239)
                     /locus_tag="ACF3UF_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFD3671807.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            20963..21994
                     /locus_tag="ACF3UF_001696"
     CDS             20963..21994
                     /locus_tag="ACF3UF_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3671808.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            22103..23635
                     /locus_tag="ACF3UF_001697"
     CDS             22103..23635
                     /locus_tag="ACF3UF_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFD3671809.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
BASE COUNT         6959 a         4438 c         4297 g         8090 t
ORIGIN      
        1 ttcttcgctg tcaatgatcg attgcaaagg tacgagcttt tcatcaggta tagaagttag
       61 cgtatctttc aaagaatgct caatgaagaa ataatcagcc atatcgctag atacacttcc
      121 aacatccgta tgacttactt caaactcgtc cacatctgct ccaagatctg caagtgcttg
      181 tttgatgttc atctctacca taaaacttgt tcctaatcca ctttgacata ctgcaaaaat
      241 tttcatatca ttcgtctcct tttcttatga tcgctaatat ttcttctttt gttgatgcgt
      301 gtaataaatc ttgaagattt tgtttattag aaagtagctt tgttaaattt gccaaagccc
      361 gaagatgtgc ctcattatcg atagcagcta aacagatgaa caaactaatg ggatgggctg
      421 gattatcaag cagatccaca ggttgttgaa gtttcagcaa agacatccct acttcgttta
      481 cgccatcttc tggacgagca tgaggtaatg cgatgtgatc gccaatatgg ataaacgcac
      541 catactgctc cacgcgctcg atcatagctt tgatataact ttcttctatt ttattttctg
      601 ataatagcgg ctgtgcggca aatgtgattg cttcttgcca gttttttggt tgatccgata
      661 attggatcat ttcttctgtt aataattcag atagcatagg acgttgatcc tccttctttt
      721 ctaaaagttt gttcatttta cgatttaata cttgatagag cttttcttcg tctacgcctt
      781 cttttaattc gatataaggc agtagcgccg acaacaattc ttgggcagaa ggcattgaaa
      841 atcctggtat cagccaatct ctttgtactt gattgatcag ctgatttttt tccaagtcag
      901 tcatgattgg atgcagaaca tagagagact ttttcttatc agtaagtgtg agaggtacag
      961 tagaaaaaat aatatcgtaa gaagtttcgt caacctcgtg taagcggtca gctgaattag
     1021 tctctgtaaa aaagatcatc gggaataatt gctgaagttc actttttaag atcaatgaag
     1081 agctaatgcc acttggacag acgatcacgg ctcttatttt tctatttctt tcttctgcgt
     1141 ccgcttttct gatctctccg ccaaatagta tagtgaaaaa accaatctct tcttcaggga
     1201 tgctcttccc tattcgtctt tctaacggaa gtaatgcttt tcttgtcatt tcgtagatgg
     1261 aagcatattg atgcttaatt tgatcgatca tcacattagg taaataaaaa gaataggaaa
     1321 tacgaaaata ggcagggacc aagtgataaa agacattcat caataattca cgaaacgaag
     1381 caaattctac ggccatcagg aattccatgc gatggatgac ttctgaagaa cattccagca
     1441 aaaaatcaag tgcaggctcc tggacatctc cttcaacgat cgatgctaag caaagagaga
     1501 aaaatataat ctccgaattt tgatgttcgg aatagccaag gccagtcaat acttgtcgac
     1561 taatgtcagt gactgcaaga gaagccaaca gttcagcatc ttttaccagt tccatggatg
     1621 tttttccaat tcgaatggtt gtcaaactca aataataagc taattcatcc attcgatttg
     1681 gtgcgaatcg aagatctgat agtgaaatcg ttttatctag caaatctcta actttggcgt
     1741 aataatcaat ggaaagggtt gcggttaaat acgtgagccc aaatcttcca gcaagtgact
     1801 gcatcaaacg agcagtgcga ttttttgctt ctcttcttaa tattgcttct gaccctagca
     1861 gcctaaaacc agttttccta gtatacgaca gctgacaatc ttccacttct aattcatttc
     1921 ttatcttttt gatatctgac aggactgtcc ctttagaaac ctgaagaaaa tcttgaaaat
     1981 gaaaaacaga aacagacgtt gcagtcgaat aaaccatcaa ataaagaaga tctcttcgct
     2041 cttgttcggt atacacagct tcaaatcgag taatatccaa aaatttttct gcccagtcga
     2101 ttgctcggaa tttctttata cggatacggg tatcatccac atattcggca aaaggagtta
     2161 attgtttgat cgcctcgctt gtatttactt cgatgatctc tgctgctttt tctagactga
     2221 tttctcttgg tgttttcagg agataactaa ttttgtagtt cacagcgctg ttcacctcct
     2281 acttatattc tagtatggta gcgcttttaa atcgaggggt gtttggtaca acttacagtt
     2341 ggattttttt tacgactgta ccgaacgatt tctatcgaat ggatacagaa aaaaagcagg
     2401 tgaccaaatg tctcctgctt ttatgaattg atttcgtccg atcaatgatg atcatgttta
     2461 ttttttgagg tcagttcttc aaatttttct ttgacatctt caaccgcttt ttcgatatct
     2521 ttttcaaagt gattgggctc attaggcttt gtttcctctt ctacagaatt tgaaccagat
     2581 aaagctgttt ctttattttc tgtttcacca gagtttgtgc cagctaatga ttcttctttg
     2641 tcttctgttt caccagaatt agttcctgct aaagccactt cttcttctgt tttaggggcc
     2701 attgaacctc ttaatcgttt gtgtttttca ccgtcataat ttgtcatgtt ggttcctcct
     2761 agtagttcta tactttttca tcgtacaata agacagttta tgcgtcaaaa aacaaacccg
     2821 attcttacaa atatgtcata tttttccttc tgattcttga atgcttttga ttccttcttc
     2881 caaaattttc atttgtaaga ttgtttcttc atctttgatg actttttctg cgccattaac
     2941 taatgtctcg taaatccctt cgtagacacg gctgtaatca ccaacctcgg aaattacttt
     3001 ttcttcatga taactccctt gttcatctat ataggtcaat acaccataat gttcgggcaa
     3061 atcgatacca aagtcttcat gatcaggcat gtaaaacatt ttcagatgtt cttcttgtcg
     3121 atcttttgtt tgtttcacga acatcccttt ttttccgtaa acgacgaaac ttggacgttc
     3181 tttgatgcgg aaataactgg attttatcga aattttcata tttccataga aaaaatccag
     3241 atcgaagtaa tcattcattc gtcctttccc taaaagttga cgtacatcat agctgatatc
     3301 atctggttcg ccgaaataag aaagaacttg atctactgta tgacaagcat gtccatataa
     3361 atagctgttc gcagtagaaa attcatgcgt attttctggt acttccggtc tgaaataatc
     3421 ataatgcatt tctacttcta aaatatcccc taattttccg ctttcgatta ctttttggac
     3481 tgtcaagaag tcagaatcga accgtctgtt ttggtaacat tggataaata gacctttttc
     3541 ttttgctaat gcaaataact cttctgcttc ctttgacgtt tctgcaaaag gtttctctac
     3601 tagtacattc ttaccatgtt cgagtgccat ttttccatat tcataatgaa attgactagg
     3661 tgtagtgatg acaactaatt ggatctcagg atcatcccaa agatcagaca gctgatcagt
     3721 atattcgatg tcttcgaatg ttttccacac tggttcagat ggggaaaaaa tttttttgat
     3781 attgattttg ttcgtaagtt ttcttgaaaa aggcaaatga tagcgatttg tactctttcc
     3841 attgccaaga taagcgattg taagcatgag tggtgcctcc ttttattgat gttttcagta
     3901 tatcctagaa aagcgcagaa agtatttata atagctattc tggtaaaaaa gttcagaaaa
     3961 acacttgtta tcattcggtt tggtgaaatt aatgttcaaa gtaaggataa aaatcaaaaa
     4021 gatagtagcg gaaccaagtg tttatcagta agatagaatt tggaggtcag atcatgctta
     4081 ttgaagaaaa actaacaaaa caagagttgt ttaccacgac agagaaacgg attgtcgatt
     4141 acatccgtag gaatatcgaa gctgcagtct acatgacgat tgaagaatta gcaaaagcta
     4201 cgtatacttc ccattcagct atcattcgtt tatgcaaaaa aatgggattc agcggattta
     4261 aagaattccg tttcgagctg gggcgggaag ttcatcaatt gattgctcag ttcaatcaaa
     4321 cgattgatcc taattttcct ttttcaagtg aagatagcac tcagcaaatt gcaaagaaaa
     4381 tggcggattt atcgatccag tcaataaaaa aagcacaatt gcagattgaa catgaagatt
     4441 tagatcaaat cggtaaagta ttgaacaagg cacagcgaat ctttcttttt gcaaaaggtg
     4501 attctcaaat cacggcaagg aaattccaga ataaaatggt caagttgaat aagtttttga
     4561 tcatggctga agaatacagt gattcttctt ggaatgcagc caatttgact agcgaggatt
     4621 gcgccatttt tattagctac agcggtcgca tccatcatta tgaacgaata atgacctatt
     4681 tgaagcatgt agaggcccct accttgctga ttaccggaaa tcagcattca gaaatggcca
     4741 aacaggctga tatgtgtctt gttatatcgc aggaggaata tgattttgct aaagtagcga
     4801 ctttctcctc tcaaattgcc ttcgattacg tattaaatac gttattctca gtgatatatt
     4861 ctcaaaattt tgaagagaat atccgcaact tgaaaaacaa acaagaattg atgcaaaaag
     4921 gccttcttaa agaatatcgg aaaacttaag aaaagatcct catttagtaa taagaaagat
     4981 agtgtttgat aggctctctt tgatatcatc ataaaaacag gctgaagttt tctttttcaa
     5041 acctcagcct gtttgtttac ggaacgattc gaatagatat attatagaaa tgaggaatag
     5101 ctaacttctg tttcttattt tgaacgattg acgaaaaaga tatataagaa ggaggaaaat
     5161 cagtatacat gcagctaaca atccatacag gaaaaatcgt ttgttctcgg atactttctg
     5221 tacttctttt tgaacttctt ttgcatgata aggaacccgg tgccctctga caagtaagcg
     5281 atgactgttg accatataag gtgtacaagt taggagtgtc acgaaatcct gccctttttc
     5341 gattctcaga tcttttgtat cagtcggttc taccgtcttg atctgatcga cttgataagc
     5401 gagtgtccgt ccattgattt cgatatagaa agaatcacct aaagtcagtt tcggtaagtc
     5461 tgtgaacaac tttgcttgag gcagtcctcg atggctggaa ataacggcat gtgtattttc
     5521 tccccccgta ggataagacg ttccttccaa taatgaggca cctttttcta gcagcacagt
     5581 attcgtttca tcaaaaattg gcaaatggac attgatctca gggatcgtca aaataccgat
     5641 cgtatgtttc tcaaaatagg ttctatcctt tttcgcaggt tcttttttct tagtaaaggg
     5701 atctgcacct ggatttccac cttcttttgc taattgctgg tttttctttg tcatgttttc
     5761 ttggatttta gccatgactt cttcattttc tttgaccgct tgttgctgat aatgagagat
     5821 gatctgctga tccagataat tattcagcgc gtcgctaaca aatggataag ctagtatccc
     5881 tattcctgag agaagcaaga aaagcatcag cagatctaga agtttccttt tctttggttt
     5941 catttgtgtt ctccttgtga tgactgtttg ataataaaag aaaaaggagc atttgcgtaa
     6001 tccgctgctc ctttttccaa ttcttgcaaa aagactaaat ctgactgtgc ttgcgtctag
     6061 caaagtacag tccagcaatc agtagaagga ctactcctgc accgatatac acatagattc
     6121 ccttaccgcc tgttgaagga agtgtacctt tgtgtttatt tggtattttt tcaggagaaa
     6181 tcaactgtcc tgctgttaca taagattgtt catcgatagt aaatgctaca cggtttgtta
     6241 atggaacata tttttctggc gctttcgttt cttccagata gtacgtgcca tattttagac
     6301 ctgtcacatc gattaaaccg ttacttgtgg ttgtaaaaac cgttgctgat tctttcgccg
     6361 atacccagct gacggctttt gtggatgggt cgatcgataa atatttcgct gtgtcactat
     6421 cttgatcacg aacgacgaat tctgctccag caagtgtttg gtctgatgta acgtcaccat
     6481 ctactttaac aaatcgtttg cccccagtaa cgacatcgac tgacggtggt gtttgatcat
     6541 ttgtatgccc gttatcgaca tttgcttggt tagaaaatcc tttggttgga tctgcttttt
     6601 cgttcaaatg catatagtaa acgaatttca atgtaccgcc aggagttaat gaaggaatat
     6661 aattcggatc aactgaaacc gtgaatccgt ctgtttgctc agtgacagaa taatttactg
     6721 ggtcgatttc tttatttcca tcatataagg cataagcata cgttcctgaa gaatcattat
     6781 caaatgttaa agcagcgtca tgagtatcga taagtttgaa tgttgtgtac ttgttttgcg
     6841 ttccttcttt atcagcgata cctaatggga tattgacaga aatctcatat tgaatttttt
     6901 caccgattgc gacatctttt ccattcaatt gaggtgttgt tttatcaact ttagacgtat
     6961 catttttgat ggtcttttct actggtgttt ggctatttgc caggatctca aaaggcgtga
     7021 ttgtttgctt ttcaatcatt tccgcattat caggagcttt tacttcttct aaattatatt
     7081 ttccaacttc taaatgatta acgatcaact ggcctttttc aatagatgcc tcggcaaagt
     7141 cattgttgcc gatgtcataa gaatgaccag taatgaaatg tttggctttg gtttgatcag
     7201 ttgtccaagt gtacaatcca tctgtgacac tttggatgta ttttttgacg cttggtgttc
     7261 cttcttcttt agaaataata aattctgctc catttagtgc ttcgttttcg gcagtaccga
     7321 tttttgtaac tttcaacgtt ccatcattac cgactgtatt tttagggtag agatggatag
     7381 tatctagttc ttctgtcccg tatttataag agccatctgc ttgtttgatc atctcatata
     7441 cagggaaagc taaaaccatg tttgcggcag ctgacactcc gtcttttggt tcttctttga
     7501 tcgtgtagac tgcatctttc ccattttgtt ttttaggtaa agataaagtg acatttccat
     7561 cagcatctgt cgttcctgaa gcaactggtg taccaggagt caaagactgg actgcttgtt
     7621 ttgctgcatc cacggacgct cctttatctc gttgcgcata aaattcttga gtgacgttat
     7681 aaactgaaaa tgaaatatcg gctaatcctt ggtattgatc gaattcgctc atttctttcc
     7741 cgctgttttg gattaaagga tcgggtaaat cagtcatttt ctttttatga aggatgactt
     7801 gagctgctgt ctcctctgca aacacttttt ttgcgccgaa gctgtttgtg agtaatggta
     7861 aaataaggaa aaggactcct aacataacgt ttattttttt atgatttttc attttttcac
     7921 tcctgttctt tttttgataa acaaccagat tgcaaagctt gcgaatacca taccaacaac
     7981 gcctaaaagt gtatttttcg tttcgtttgt ttttggaaga aatggacggc tattttcttt
     8041 tttattgact actttcaata tactgtccgc ctctttatcc tcagaaagaa aagttgaaat
     8101 ggtaaacgga atttctgttt cacttaaaat ataaccagaa ggtgcttcga tctcttttaa
     8161 tcgataactt cctgttttca acccggaaat tgaaaaagcg ccatttttat cggaaatcag
     8221 gtgaagcgca tctgattcgt tctttgtcca cttgtatccg ttggctgttt gctggaggta
     8281 atttcctgct ttgtttttaa taaggaatac tgcgccagct aatcgtttat ctggtttatt
     8341 tgtctcgatt ttgacaaatt gcttactccc tgtatataca gagactttct ttgtactgac
     8401 accaaaacca aaatccagtg ttccgttgtt gttgatttcc ttgttcgcct gtgctgtact
     8461 gcttagctgc atctgataag aaatggtcag tttttttcca gcatattttt ccaacgaagg
     8521 gatcgaaaat aaaacatcaa atccgtgagg tttcttgtgt atgacaaagc cttctgtcag
     8581 cttttctcca ttcgatgaaa tcgttaaact attaggtaaa aacgttaatg cttcatccgc
     8641 actatctgac aattcgaact tttgatagtc aaggatattt acaggaattg tcgtatgcaa
     8701 ggaataagtg attttttcac caatcgtaaa atcatttcta ggctcttcta ataccttctc
     8761 aaaaggtgga tcagggtagt cgttttcttc atttttagga tacaaatgga tagttgaaag
     8821 tttttgattg ttttgtccat gtacaggaag aacaactacc atattctctg ccttttcttt
     8881 gacgacttct ggtactttgg attcaatgaa aagatacgct ttatctcttt tttcttgatc
     8941 tttagcggcc agagaaaaag aagcgatacc atcttcgttg ttaagagttg tagttgttgc
     9001 ttctgcggta aacataccgg aagacgcacc gttttttgcg atctctgctt gtgcttcttc
     9061 taccgttttg cccttttccc gtagatggta aaaagaatct gtgacatcat aaacttggaa
     9121 tgtgacacca tttaatcctc gatacgtttg taataaagct ttttcttgtc cgtcatttgg
     9181 atgatttttc ggcagttgcc cgtttgggaa aagcaatttg tgtaaagtaa tctgaaccat
     9241 ttctgtttct gtttctgttg ctacctgagt aaaagctggt ttaaatagta acaagaagag
     9301 acacatacta agccaaccaa gttttttcat atttagctgc cccctctttc ttttttcaaa
     9361 aaaagatacc aaatagaaaa cgcacaacca atcatcccta ctagatagat tcctaaacgg
     9421 ccaattcctc ccgtttcagg taatggtact tttgcctgat tcgtgatgtc taaagaaatc
     9481 tggttgtttt tggctcctgg tgacagaaca gattcatgat cttgtccatc cacttgaatt
     9541 gacccatctt cgtgtataac tatagtaact ggctctttta gaccttggta tccttctggt
     9601 gtaaaagttt cggtcagcgt ataagttcca ggttttaaat tttcgaatag aaaggtatct
     9661 gtttcttgtc catcttttgg cgattctaag tccatttctg gtccctgcag tctgaatttt
     9721 gctcctttta atgtctgtcc gttgtcttct tttttgtgta ccgttagatc aaacgctttt
     9781 agtcgatttt gatgagtgag cgtccataca ttatttgtca tctcggtatt ttttcccgtg
     9841 taaatgattt ttccatattt atcgatttgg aattcataat ttcccggcga agtatcatat
     9901 ccggcaggac cagctgtttc aacgactcga tatttaccag gtgtgagtga atcaaaactg
     9961 gcaagacctt tttcattcgt tgtttggctg tcaattggct gataagtacc atttgcttct
    10021 tttttctgta gggaaaatgc tgctccttta agatttatct ctttgtccgt cccttgcatc
    10081 gcatacttac gtactgctac aggaacttca acaaaaggat tttcaatagt caactggatc
    10141 gtatcatcgg aagtagtgac tgtttttcca tcaatggtta ccgtaccatc agaagcgatc
    10201 ttgatttccc aagtagtctt tttgcttaat ccatgccctt ctggagcttt tgtttctgtc
    10261 agcgtatagg tcatttcttt ttgcaatttg acattttctg gaagagaata ggttccgtcg
    10321 ccatgatctg ttagtaaagt atcaatagaa tctcctgtta atttgaaaac agcgccaata
    10381 agatcctttt cacctgtaga ggaatttttc gttattttca agtttaacgg tgtgaattgt
    10441 ttagtatttt tccatgtcat tgcatctatt tgttgagaat cgtatcctgg tacaggtaat
    10501 tctttgattg tttggtaact gaatgcttga ccttgattat tgtattgagg tagtgataat
    10561 atctcttgat aactttctcc gctatttgca gataatttgt caatgtctgc acgttcccac
    10621 gtatttgttg tatctttagc tggtttaatg attcgaatat atccgttttt ccaagctgca
    10681 gcatttgtcg tatgttcccg ttgaatctca aaagtaactt gatctggacg atcagctaga
    10741 ttgttgtcaa attcttccca taactttttg atgtgaagac tgactccggg agctttagca
    10801 gatggtatac cgaattcagc taattcattg gtatcaatgt ttggctggaa agttgtcctg
    10861 ccgttcattt gataccagaa atttggatgg aagtcctcat tttctgtttg gattctcact
    10921 tggtaatgga tttggatttc ttggtctttt cctaaataga tctgattgct cttgatggta
    10981 tttccttcta tggaaataga tggagtgacc gttgtaggac ttgtccccac actcttgact
    11041 gaaagtgtac caggctgata aatgaatggt tctgcgattg gatcatttat ttgtccattg
    11101 cttacagttg ctgagatctg tacagctttt ttggctaggt attcagagat atctgttgca
    11161 tgatcagctg attcatagta aagatcgcct ttttcatctg atgaaaccat ttgtcgcata
    11221 cgagactcta cttctgcttt tgagagacca gctgccggat cgctttgaag ttggatgcca
    11281 agaccatgta tttcgattcc tcgttctttg agtgccatcg cttctccgat ggttgcgata
    11341 aacgtactgt cgattcttct ggatagattg ttttggtcag gtgcatcata gattcttgag
    11401 attagagaag tatttcccgg ccgatcttgc gtattagaaa actgagttcc gtaataattg
    11461 ctgcttgatt gtgcgtgtac ccgctgtact ttataggaaa atgttggtac accatccgtc
    11521 agcaaaacga tcactttttt atgtccattt ggaacggata gcatgcttcc tgcatctctt
    11581 agtgcttttt gtgtaaaagt accaccattt gtccgtgaag gtgtaatgga ttttacttga
    11641 tttttcactg aatcaaatga acccatctgt actgcaccgt tactgtagct atatccttcg
    11701 cttgagtagc cgacatatcc catattgatt ttgtctgtga taccgctatc tgctaaagta
    11761 tcgacaaaac gatcgacacc aatctttact tcaccgatcc gattattgtc gttcatactt
    11821 cctgaccagt ctacgaccaa tacgagatca agaggcgtga tatctttttg tacatttcca
    11881 cgagcattca aataaacatc aaacaatccg ggtgtacttg tttcctttgc atactttcgt
    11941 atcgcatagt ctgcttgatt accggttcct ccatattcga tatacgaatg ggtccgatca
    12001 ttaggatctc cattccaaga atttatacca tcccattgat ttgttccgtt tttattgcct
    12061 tgatgatcaa gaacatttgt atttcctgta ggttgccaac tggctttagg ataagtgccc
    12121 tgatcatctg ttgtatattc tgtaggaatc gtttgattag atggcacact cacagctggc
    12181 aaggataatg taggcaatgt aaatgggctg acagaatttt cgttttcttt tgatgattct
    12241 tcttctattt cgtctggctt tggtactgac acatctgtat ctttcttatt ttctgtctca
    12301 tcaataatgt catattcttt attatcgacg atcagcttgt ttgcctggct gtggtaaagt
    12361 gctggatcga ttggaaaact cagatcgata gtttgtttag tgtttgatga gatttccaac
    12421 gtaattttcc cgctatttac ctgataagca tagccatctc cttcttttct ttccacatca
    12481 cttaagtaat tttcgactag accaatttct ttttctatct tttcagcact ggtgttattc
    12541 gcatttagct tgatgttcag tgcttttttt ccagactgat ccgaaatgac ttcagctgaa
    12601 attgtttcta aaactgttgg atcatctgta gtgtctgcta ttgcagataa tggcacaaag
    12661 tttgataaac tcaatattat cagcatgaaa ataactttca gtttcttccc tgtggtcgtc
    12721 atttttcccc tcctttttct ttttttctgt tttgacgtga atagtgaaaa ttattaaaat
    12781 aaacaggcgt tacataattt tatttatttt aatatgataa ttattatacg aagggcgcta
    12841 aagggaatca caccaatttt cataccaatt ggtttcattt atgaagttga ttccttcgat
    12901 taatgagcgt ttcattgaaa gaaaagggtt gagggagaaa aacatatgat caggttgttg
    12961 gaattaaact atagaaagat ggaaaaaatc attcgaattc tgtccatttc tgacaagtgg
    13021 atgactaaaa aagaacttgc caaacgaatt ggtagttcag aatctacatt tgtaaggtat
    13081 atcgaagaga tcaaaatccg ctggggaacg gatgtaacga ttcaatcttc acaaaaattg
    13141 gggtatcgtc ttgaacattt gaatgtacca gcttatttaa atgttctgat ggaaatgtcg
    13201 caaagttcta caaacagtcg tttattaaat gagattattg tcaatccggg taaaacgatt
    13261 gagtattatt gtgaaaaaat ttccatcagc cggtcttctt ttacacgtaa gttgaaacaa
    13321 tgcaatcaaa ttttagaaag ctatttatta aaagtgatcg ttgaccaagg ttttcagtta
    13381 actagcctta aaagtgagct ccagttgcgt atctttgtta cctttttctt tttaagttac
    13441 tacggaagac gcacgttgcc atttccaatc gaaaaaaaga agatcaaaga aattatggtc
    13501 aagaataatt gtcagatgaa tttgtttcag gaagaaagcc catatgagca atctttcttt
    13561 attatgtatt ttgttgtgca tctcatgaga gaatcccaag gaactccatt tgaatggaaa
    13621 gctggagact cttatgtaca gttgataaat atcgataaaa aagacttctt aatcttgaaa
    13681 aatctcttag gaaaattgaa gtacagcagc tatataaaag tagtgaacta ttttgtcaat
    13741 acgatttttt cagaattttc ggagaaagaa aaaaatgaaa tcagtgagca gatacgaaaa
    13801 aatatgtcct actgttcgtt ttcatccgct gattgcaaag aaaaaaacga agaatatgtt
    13861 gttcaattat taacgcaaat ttattttttc tcccgtattt tcccatacga tacgactcat
    13921 ttgacgatcc gtgcaactta ctttgcacag cagatgcaac accgccagat acgtctatat
    13981 gctggatttc gtgcagaact tcaattttat tccactctac tgaatcagaa tctgatttat
    14041 tatttatcta gctatatctt ttggatgctt atcggtaatc ctgaaattca ccattatact
    14101 tctgataaaa aaatactgat tatcagcgac ttaagtcttc gacatagtca atatattgaa
    14161 gaatatatca gtgatattct tgctgtgcat aaaattcact ctgagacaac tgctattact
    14221 gaagatcagc tgtcgaaata caatcttctc gagtatgatc tgatcgttac gaatcaaccc
    14281 attttgaatg cccatgttcc tcatatattg attgatgata gtgtgtcatt cgcaaatgaa
    14341 gaagaactca tccgcttatt cgagttatga ataatcaaaa aacagctatg tataaaccac
    14401 cctgataaaa atttcaggac aaatacacat agctgtttct ttttattgta ttccttcagc
    14461 aatccaacga gatttatagc gaaagtcttt taacaactct tcttttgtcc aattatttgc
    14521 aatgagatcc gtcaaagtgt tcattacgag ggtcatggaa aagtatagga aactaactgc
    14581 ttcttccgac gattgaatgg agaaatgatt gattcttaat aattccagcc atttttcgtt
    14641 cattggagaa tcagccgata gttctctacg tttggttgtc tgctgatcat ttcgctgggt
    14701 taacaagtat aacctttgcc aatagatact ttcgtgatct aagtcgcagc accactctaa
    14761 atatttttcg atccccaaaa agaaatgttg tttgttttcg ctaatgaatt ttaagatatc
    14821 ttgatggact atgtgagaac tgcttttgat cgtatacaaa taagcatctt ccaaatcttg
    14881 aaaatattta taaaaagcac cgcgcgacat ccccatcttg tcaacgattt ctgagacttt
    14941 gacttggctg atgtgctgtg agcaaaatat ctccagtaat aggtcatcga ttctctgttt
    15001 ctttgcgttc gataaattga aaaaagtttc ttttggcatc cacatctctc ctttatctct
    15061 gattatacgt ggatagccct tcattgtcat gaaggattca ttccttcttt ttctcttctt
    15121 ctgtcaagta cccatcttcc attcgataaa cgcgatcact ccattgaatc atacggacat
    15181 catgagtaac cataatagtc gctttttgtt tctcatgagc ttctttaact agtaatttga
    15241 cgacttcata tgcatgatct gtatccaaac tagctgttgg ttcgtctgct aagatcaagc
    15301 ttggctcatt atataaagcg cgagcaattg ccactctctg tctttctcca ccagaaaggt
    15361 ctttaggata actattttta agtgactgga tatctaaaga ttgcagcaag gaatcgattt
    15421 ttgttgaatc ttcttttttt gaagtaactt ggtcaactag ttcaaattgt tcctttaccg
    15481 ttaaaaaagg aatcaaatta gagctttgga gaataaatcc tatttcttta aagcgtaaat
    15541 ctgctcgttt tttttctgga agctcagtta gtgagtgacc gttgatcact atttctccgg
    15601 aagtcggtgt ttgcaatcct cctgaaatgg taaggaaagt acttttacct gaaccagaag
    15661 gaccaatgat gctgacgaat tctccttcct ttacataaaa atcaattgct ttcaaagctg
    15721 agacctttgt atgaccagaa ccaaatgttt tggtaacttt tttcatcgtt aatatttttt
    15781 tcatttttat taacctccta ttgctgtaat tgggtctact ttggttatcg tacgtatcga
    15841 aaacaatccg cctagcattg cgacaatgat caaaatccca ctatatagca accattgtga
    15901 ccaaaaaaca gcaaaaggca tcgcgcttgg taaaatcaga ctagtcaaat aagcaaacaa
    15961 aagagcaagc agaacgccta ccaccccaac aataaaggac tgtgctacta aagatttagc
    16021 gatgaagaaa tttttgatcc cttgtgcttt cattactcca aaaatagcag tcttctgaag
    16081 tgtcatcacg tacatgaaaa taccgaccac ggcagcaacc actaagaaca aaaagtatat
    16141 catcgcattt aaggtcatat tttgggcaga atagccagga atactttcaa tgaatgtccc
    16201 aatagttaat aactgtagac ccttcgatgc tttttctttc gaaattttag ctgaatcctt
    16261 tattacgatc ccattgatcg gctgttcttc ttcagaagca aacggctgtt gtccatactt
    16321 caaagcagtc cacgtatcta gggacgcata gatgacggga gaaactgtgt aataagtttc
    16381 aggaaagata ccgacaatcg tcaaaggatc gtcgtaactg ccaattttga tcgtatctcc
    16441 aattttatag cctgaatcag ccagattttg agagatgatg atttcattct ttgttttaaa
    16501 ttcatgccct ttcgtgagtt ttggtaataa aaatgcttct ttcgttgtgc cgaaaactgt
    16561 aacattttct ttgttttttc ctttgattgc tccgctgtac aatccgattg gtgctttctc
    16621 tcctccttca atgtatttca gatctcctct tgttaattgt gaagctgcaa atacttgatt
    16681 tgcatcctcc gacaaaacaa tctcttgtgc gtcccaatca tcgattgctt ttttaaactc
    16741 ttctgaaagt ccattcgcta gtcctgacaa catgaatacg acatacgcaa tcaagaacat
    16801 aataccgacg atcaagccat atcgtaattt agaatagcga atttctttga tagctagaaa
    16861 catttgtttt tcctccctat gatagattga tagtgacaaa atgtcacttg ttgaatagtg
    16921 taactctaaa gtgacaattt gtcacttgtg ttgttttttt cttatcaata aattgtctaa
    16981 gacatctttc gataaaacct taacatgagt cataaaaaat ttatttaagc cttatttatg
    17041 ctttccatga taaactaaag tgaccaaatc aatgaggtgg gaaaatgatt aaactattag
    17101 tagtagaaga cgataaagta ttatccaata atataaaaga aatactcgct gcaatcggcg
    17161 agataacaca agtttatgat ggtagtgaag gactgttcga gttggaaagt ggagtttatg
    17221 atcttgcaat cttggatttg atgatgccgg aaatgaatgg atatgaagtg ttagcaaaaa
    17281 tacggaaaga aaaaatacag actccagtat tgattttgac tgcaaaagat agtttggaag
    17341 ataagattga aggatttgaa cgaggtgcag atgattatct aacaaaacct ttctatcgag
    17401 aagaactgat catgcgcgtg aaagcattat tgaaacgctc gctaggtctc tttgatgaaa
    17461 atgttctgaa gtataaggat atcagttgtg atttaaaaag caatgaagtc ttgtataaag
    17521 aacaagtttt gcccatacaa ggaaaagagt ttgaattgct cgtttatttt ttacaaaata
    17581 agggaatcat tttgacaaaa gagcagatat ttgaccggat ctggggattt gattctgata
    17641 cgacgattac agttattgaa gtttatatga gcaacttacg aaaacatctg cgaagtactg
    17701 gattggataa agaaatcaaa accttacgta atgtcggtta tatactgcaa agggtgtgat
    17761 gcaatgaatg gagatattac acgaaagcaa cgtagtcgct tttttgcgac aaatgtagca
    17821 gcatttgctt ttatcttttt tcttttggga ttcattactt tacagatatt aaaccaatct
    17881 gcatacagag aaacagatct gtcattagag aaaataaatt ttgattctcg aacagtacaa
    17941 ttagagatac aaagatatca gcaaggcgat ccctttttaa acccgactca aacggaacaa
    18001 aacagaacaa acatggaaca gccattaatg gaaccatcaa atgaccgttt taacactcaa
    18061 gtgatcttgt ggtctaaaaa tggtgagata ttgaataaag cagctattgg tgggcgtttc
    18121 aaccaaatca aagaattaaa aatggatacg aaaaatctga ataccatcca aaatattgaa
    18181 ttaaatgaag acagtggctc atctgccctc tctttccgtt cgattacgaa aaaagcggag
    18241 acgaatcaag atggcgttgc ctacatccaa attttagaaa atacaaatca aatcaagaat
    18301 tcattagcga cttttcgcac gattatgatt ttgtgtatga ttgttttttg gattctctct
    18361 attggtatca gttattactt gtctagtcta agcatgcgcc ctattattct ttcttggaga
    18421 agacaaaaag aatttgttga gaatgcttct catgaattgc gcacaccgtt aacgattatt
    18481 caaaatagtt tggaacatct ttttaccaag cctaatcata ctattattga agaatccgaa
    18541 agcatcgctc aagcattgtc agagacgagg cgcctcactg gattgacttc ggatttgctg
    18601 acaatcgctc ggaatgattc tgatcagcag ctgctttcaa agcaaatgat caatacacaa
    18661 gaatatatcg aacaacttgt taaaccattt caagagatgg ccatcataga tggaaaagag
    18721 tttattctcc ataacgatgc aacattagaa gtaccaattg atgaaaaaaa aatccatcaa
    18781 gttttggtta ttttgctgga taatgcatta aaatatacga atccagaaga taagatcatt
    18841 ttggattcat ctgttaacca taaagaatgg ctgattcacg taaagaatac tggcccttct
    18901 atcagtgaag aagatcaagc aaggattttt gatcgatttt atcgggaaga tcaatctcgg
    18961 gcgaaagaga ctggcggata cgggcttggc ttggcaattg caaaacaggt aatcgaacag
    19021 catcatggac agatttctgt atccaattat cttccacaag gagtcgattt taaagtccaa
    19081 ttgccgttga agcctaaaaa ataatgctta tccctaaaaa agggctgtga caaaaatctt
    19141 gtcacagccc ttttttgttg cgaataaacg gtgttccaga agtagcttct tcggaaataa
    19201 gccgaaattt ctttaagctg accacttctg tcacaacctc tttagcttac gcttacgatt
    19261 ttttattgcg gtcttcaatg tgtacatcac cgcttgtgtc aatatccaat tcttctcggc
    19321 taacatcttc tgtcactttt tcaacatctt catgttcttc tttatgaatc ccaacttctt
    19381 cacgaataac tgtatgtttg cttacatcta cttgctcttc tttgattggg atagtaatcg
    19441 tgtcatcttc caatttttcg tctgttccct gtgaagattg atctgttact ggtttgcgtt
    19501 cgatgacgat ttcttcacgt ttgaccggta cttctaccgt ttcagtatcg ttgaccacat
    19561 gtttgtggat gtcgacttct ccagttgtca catcatgtgt atttacatct aatttttctt
    19621 cttttagttg aattgtatca tcatctagat ttggtttgcg atcgatgtct tcagtcttgc
    19681 ttgtacccat tgtatcagtc tcgccaggta cgtccatcgg atcagttcct ggtgtcatat
    19741 tcaatggatc cgttgtattt tgaaagcctg tcgtgccacc tacgtccatt ggatctgttc
    19801 cagtgccagt ttctaatcca gtccccattg tgcttgctgg gctaacagta tcttgtgtat
    19861 ccattgtatc ttctgttgtt tctggctgac gatagccttt tactgtgatg acaaattttc
    19921 catcagaaat atctcctcta tattgatata aaggatcatt ttctggtgta gccgtctcag
    19981 aatcataggt atcaaaagaa aaagtatctt ttattttttc ccataaagaa cggtcttctt
    20041 caccatccat ccgattttca tctgtttcaa catctatacc agacaatccg tcaaatccta
    20101 gtctagatgc tgcttcatca gtagtataaa taacgatatc atctcgttca tacccttcgt
    20161 tacgcaaccg ttcaattact gataatgctt cttccctcgt actatagctt ccgatgaccg
    20221 ttaaattttt ctcttccatg taaattcctc ctagcaaata gatttatgat tggtatattg
    20281 ttacttataa atttattcta taggagacga ttgttttcta caaatattta gattggaatt
    20341 tgattaaaac aatttaattg aaatttgaaa acatttatgt taatgaaagt catattctaa
    20401 taaaatgtca tttgtttcta tatgaatttt tatgaaaaat ttcatataat ttccactcgt
    20461 tgtgatggtt taatttatcc aatccatcaa taagcaaaca acttatataa aaaaggatta
    20521 attctcaata taattgctcc taccatagaa taaatcttca tgtaaagtaa tgaagtacca
    20581 actatttcta atacttcttt aagaattatc ccaacaatat cgttagacaa accattattg
    20641 aataaatgga gagccaatcg attctgaaaa aatgttttct aatttttcgg aaataaaaga
    20701 aagagcctcc tgccattaga acgaaccaaa tccatttcat tgctcatgaa gtaaccacat
    20761 agctaaaaag aggataaatc aattaaaaga tcaaaagaat gactgcacta ataaaataac
    20821 taaaaatgta tcttcttact tcatatcttt tagctagtac ttagttaaaa atttgcttcc
    20881 taagatcaag acaaactgtc tatcttcatt tgatgaaatg cggtaaaata tagaaaatga
    20941 acactattgg agggaatttg taatggacag caaaactaga aaacaactgc aagaaaagtt
    21001 aaagcaacgt acacacttgc tcccttccgt ctttcaacag tttttagaag aaaatcgttc
    21061 ttccctttca ttaggcagtc gctatgaata cgcaaaagat tttcatctgt ttactgatta
    21121 tttgagaaaa gtattttctg aagaagtgga tgatcagctg attatccatt tagaaaaaca
    21181 agattatcag aatttcttag ctaaaatcta tcgacatact cgttcgttcc aaactacagc
    21241 gaaccaagaa acggagcaat tgtttgaaaa tagctattac gggatttcaa ggaagcaata
    21301 ttcattaaat cattttttac gatttttgta tcaaaaagga ctgattgaag aagagatttc
    21361 tcttttgggt acaagtttac cggaaacaac caaagcagct ccgcgatata tcgatgcaga
    21421 acttttcaaa gattttgagc atttgtttat cccgattgaa ggctttcaaa caagcagaga
    21481 agctagcttt gaagaaaaga atagaccgag gaaccttgca attactgcca ttcttctgta
    21541 ttgcggatta aagatccatg aagtagtaga acttaaacgt aaagatgtat ctttgaccaa
    21601 gcagattctt aatctgaata gaaaagaaaa cagactgaat aaagtaccaa taccaaaaga
    21661 agcgatgcca tttctggaga actattttaa gttaacagca caaaatacgg acgaaaattc
    21721 ttttgttttt cgttcctcac atgatcagca aatttctcct cggactattc gccaaatttt
    21781 gagcaaaatt acagtatata aaaacgtatc gccagaacta tgcagaaaaa catatcgtta
    21841 ttatgcagaa ctatatttag atgatgctga cgcggtaaat tatttatgtg gtaatcgata
    21901 cctctcatcc cattcttttc aagatatctg ggaaaagatg gttgattttt cttatcacga
    21961 attagcggca ttcgttcggg tttcttccat ataaaacaaa tgtatgatct ttttttcaca
    22021 ataaactatg ttattatata aaggattatg ttacgattat cttgaatttg tatattactt
    22081 aacaaaagat aatggagtgt gaatgatgga gaccataacg tattcccctt tgaacttatt
    22141 tacgaatttt caagaagctg cagctaactt ttccgagacc ccgattatct ttgatgagcc
    22201 actttcagct ttcccagaat taggacttga aacaacttac aaaaaatgct gcgaaagtgt
    22261 gttgaaacgg gcttatcaat tggctcatct tggagtgaaa tccggagaca aagttattat
    22321 ttataagagt tccgcttttg acacatacct tctagctgtt tctgtgtctt accttggtgc
    22381 agtgcctgtc atgacttctt atcatctacc aacaacaaca atggaagtat ttatcgatcg
    22441 tttagaagac cctttcattt tatttgatga tgagacaaaa aagcgagtga gagaaatttc
    22501 aaatggaaca aaatcaaaac agattcctat tctttattta atggaacaac ctgctttgtc
    22561 tgtttctcaa tcatttttag acaaaaatga aatttcttat atgacccata cttctggtac
    22621 aactggtatc cctaaactta tttgtcattc tgctcattct atgggatggc ggacgaaatg
    22681 gcaaaaaaca gttttcacaa aaatttcgga aaagaaatta atcgcttttc acatctctcc
    22741 agtgcattcc agattcaata ttggtatctc ttctttgatg tccatgggat ttcctatgat
    22801 gcctttagca aacgcacaaa gttcaaaagt tgttcatatg ttggaagctc accggccaat
    22861 tgcactagag acccatccga ataactttgt tcagtggcgt tttactgcta aggagcatcc
    22921 agaagctttt tcgggtatcc gatactatca ctccactttt gatgctataa acaaccagac
    22981 aatgaagaca tttttgcgaa cgtcgatggc acaggatgcg gtatttcttc aagtatatgg
    23041 ccaaagtgaa tgcggaccaa tgattcttaa ggctcataca ctagagagtt tgaaaacaag
    23101 tgatgcaaga gatatgggcg ttggactgga agacatgaca agcgctcgga ttacagattc
    23161 agttgggaat gtcctacctg aaaacacaga tggtcatata caattactgt ctaaaggacg
    23221 ggctttgact tattacaagg aagatgcacg gttccaggaa aatgtttatg gcgattggtg
    23281 ggatagcgga gattacggtt ttatggataa gcatggccac ctatttttga aagatcggca
    23341 agtggatttg atcgaaacga tcaatagtac attagctatt gaagactttt tattagattc
    23401 gttagatttt ttggcagaag tagtgattgt aagggataaa aatcattctc cacaaccgat
    23461 tattgcttta gctcctgata aagaaatgga ttggaatcga tggtgggagc aagtccatga
    23521 acttcctcgc ttgaacgtcc ctatcatccg tgattttgat gcaatcccgc gaacagctac
    23581 aatgaaagtg caacggcttc aaatcgagaa agaattaaaa tcacaaaagt cctaactatt
    23641 taaggaaaga aagatccatt ttggtctttc ttttcttttt gtttttttaa attggatgag
    23701 ataaaaatat gccaattggc tgtttttctt ttttgaaaat ttcgttatac tcttattcat
    23761 ggaggaaaat gttatgaaaa gaat
//
LOCUS       DAXLPY010000040        23740 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.040, whole genome shotgun sequence.
ACCESSION   DAXLPY010000040 DAXLPY010000000
VERSION     DAXLPY010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.040"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(74..376)
                     /locus_tag="ACF3UF_001698"
     CDS             complement(74..376)
                     /locus_tag="ACF3UF_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFD3671810.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(402..833)
                     /gene="ruvX"
                     /locus_tag="ACF3UF_001699"
     CDS             complement(402..833)
                     /gene="ruvX"
                     /locus_tag="ACF3UF_001699"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFD3671811.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(830..1096)
                     /locus_tag="ACF3UF_001700"
     CDS             complement(830..1096)
                     /locus_tag="ACF3UF_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFD3671812.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(1350..2075)
                     /locus_tag="ACF3UF_001701"
     CDS             complement(1350..2075)
                     /locus_tag="ACF3UF_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFD3671813.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(2441..2511)
                     /locus_tag="ACF3UF_001702"
     tRNA            complement(2441..2511)
                     /locus_tag="ACF3UF_001702"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2477..2479),aa:Gly,seq:ccc)
     gene            2628..3380
                     /locus_tag="ACF3UF_001703"
     CDS             2628..3380
                     /locus_tag="ACF3UF_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFD3671814.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            3396..3875
                     /locus_tag="ACF3UF_001704"
     CDS             3396..3875
                     /locus_tag="ACF3UF_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFD3671815.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(4126..5706)
                     /locus_tag="ACF3UF_001705"
     CDS             complement(4126..5706)
                     /locus_tag="ACF3UF_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFD3671816.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(5699..6442)
                     /locus_tag="ACF3UF_001706"
     CDS             complement(5699..6442)
                     /locus_tag="ACF3UF_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671817.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(6618..7394)
                     /locus_tag="ACF3UF_001707"
     CDS             complement(6618..7394)
                     /locus_tag="ACF3UF_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFD3671818.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(7642..8478)
                     /locus_tag="ACF3UF_001708"
     CDS             complement(7642..8478)
                     /locus_tag="ACF3UF_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFD3671819.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(8489..9418)
                     /locus_tag="ACF3UF_001709"
     CDS             complement(8489..9418)
                     /locus_tag="ACF3UF_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFD3671820.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            9610..9963
                     /locus_tag="ACF3UF_001710"
     CDS             9610..9963
                     /locus_tag="ACF3UF_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFD3671821.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(10037..10693)
                     /locus_tag="ACF3UF_001711"
     CDS             complement(10037..10693)
                     /locus_tag="ACF3UF_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFD3671822.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            10919..12853
                     /locus_tag="ACF3UF_001712"
     CDS             10919..12853
                     /locus_tag="ACF3UF_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3671823.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(12939..14162)
                     /locus_tag="ACF3UF_001713"
     CDS             complement(12939..14162)
                     /locus_tag="ACF3UF_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3671824.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(14156..16027)
                     /locus_tag="ACF3UF_001714"
     CDS             complement(14156..16027)
                     /locus_tag="ACF3UF_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFD3671825.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(16048..17166)
                     /locus_tag="ACF3UF_001715"
     CDS             complement(16048..17166)
                     /locus_tag="ACF3UF_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3671826.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(17249..18082)
                     /locus_tag="ACF3UF_001716"
     CDS             complement(17249..18082)
                     /locus_tag="ACF3UF_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671827.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(18075..18992)
                     /locus_tag="ACF3UF_001717"
     CDS             complement(18075..18992)
                     /locus_tag="ACF3UF_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671828.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(19219..20343)
                     /locus_tag="ACF3UF_001718"
     CDS             complement(19219..20343)
                     /locus_tag="ACF3UF_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3671829.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            20526..21434
                     /locus_tag="ACF3UF_001719"
     CDS             20526..21434
                     /locus_tag="ACF3UF_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3671830.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            21575..23188
                     /locus_tag="ACF3UF_001720"
     CDS             21575..23188
                     /locus_tag="ACF3UF_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3671831.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNNYTSARILAGLGIKAILIEE"
BASE COUNT         7392 a         4658 c         3966 g         7724 t
ORIGIN      
        1 gtgctaaacg aaaaaaccgg gctctacttt tcagagagtc cagcttttct tacaccttat
       61 cgattctttt gttctattct tcttccgcca tgaatgtatt gaatacttct tcgatcatat
      121 cccattctgc gtctgtttcg atttgttcta actcgccttc tgttccatct tcgttttcga
      181 tgtatgcata agcttgtaat tctacatctt catcttctga aacaccagct ggatataaaa
      241 gaacatagtt acgtccaaat tcttcttgtc cgtcaactgt tagcaagatt tcgtataatg
      301 tttcatttcc ttggtcatcc accaatgtga tgtgttcgtg tccttcgtgt tcgtgggaat
      361 ggttatgttc tgtcataaga ttacctcttt tctttttatt attaaaataa ttgcttacct
      421 gagccgtcta aataattttg taaaatcatc acagctgcta atttatcgat gacttttttt
      481 cgtttcgctc ttgaagtatt tgcctgctct actagcatac gttctgcctg aacagtggtt
      541 agtcgttcat cttgataatc aaccggcaag gagaatagtt ctttgatctt ctctccatat
      601 gacatggaag cttctgccct tggtccgatg gaattgttca tattcttagg taatccaact
      661 acaaaacggt ctacttcgta ctgcgccact aattccttca accgatcaaa accaaactct
      721 tcttctgcct cattgattcg aatgatttct actccttgag ctgtccagcc aaagggatcg
      781 ctcacagcaa cgcctactgt cttagaaccg acatccaagc ccattactct cataaattca
      841 ctccatgatt tgagaggtag tctttgacaa ttacttccat gatttcatcg cgttcgtgac
      901 ggcgaatcaa atttcgtgca tcacgataac gaggaatgta ggccgggtct ccagaaagca
      961 agtagccgac aatctgattg attggattgt agcctttttc ttccaaagcc cgataaacaa
     1021 tcgctaatgt ttcgctcact tcttttttgc gactatcgtc aaaaccaaaa cgtacggttt
     1081 catctgtaaa acccatgatt ctacacctct ttcccgcaag gtaattccag cttaccttct
     1141 acacccttat tttactcgaa gaaagggaaa actacaaaca aatattccaa acttctgaat
     1201 aaattaagaa acacgatttg tctgattttt ccttttttct gtggcttttt caaaagccct
     1261 ctttccataa agtatacgct atatttcttt gaaagtatgt ttttacacaa ttttttcata
     1321 aagttcataa aaaattcgaa ttgctgctac taatttttcg ttttcgttgc ttgccctgtc
     1381 tcataattga tggtgtagcc atcttgaaca ttgtagataa agacattgaa ttcaattttt
     1441 ttgtcttcaa tgctttctgc ttccaactgc acacctcttg ctaccagttc atttccctcg
     1501 aaatgaggag tgacacgata gcgtacatga tgatttgttt ccttgatata tgccgcaata
     1561 tcattttcgt gggcaagcat gtacggagca ttcaacgaac gtgtccctgt cattaagttt
     1621 ttaatgttat tattttgacc agtcaactgg aaaccaatca aatggctgcg gttgtataac
     1681 cattgtccgt cacttaattt cttttgtttc caacctgtcg gatcaatata caaaggttct
     1741 ctcttttcag taggaaacaa gtcttttccc aacatcgcat tggcttgtcc tactctgttc
     1801 aatttgtcta tatttgaata gctttcccat gtccctttgg aaagactaag atcctctttt
     1861 gtaaactccg gctgattccc attgatttct atttcttgat gttttccatc atattctggc
     1921 acatccgcta cttgagaagc ttgcggtgtg gaatcaaaaa tggttgtaat ttgttggaag
     1981 atatctgaat ctttttgtgt ggtggaaata ccgagtgccc ctgcaatcac agcagcgacg
     2041 atccccacga tcgccttggt tgtttttttg ctcatttctt tactccttta ctaacagttc
     2101 cctaaatctt aacatatgtt cccctataaa taaatactgg aaagaaatag aaacagtaaa
     2161 aaaataaaac cagtttttag acggcttaag aatacaaaaa aagagacgga ttcatcgtct
     2221 ctactcaatc acaaaacact atttacaagg tatttattat cattcaaaaa atttttctta
     2281 atactcaaaa ctaaacggct tctgtacgac ctcttggtaa acagtgttca aaagcttgca
     2341 tctgcggtaa taagtccaac caagtcaaaa acataagaag cttttttgct tgactattct
     2401 tattacttga tgcagggcag ctttttcaca gcctctttta agcgggtgac gggaatcgaa
     2461 cccgcgacat cagcttggga agctgggatt ttaccactaa actacacccg cgatacaaaa
     2521 acagtatacg cctctttcac tccttcctca agttttttta ttctttacgc ttccgatatg
     2581 ttttgtagta aaataaaact aatcaatcaa ttattggaga agatgctatg acgggaaaag
     2641 aattagatct gttgctggac acttgtttac tcgctgggaa aatcatgatg gaaagcaatg
     2701 cggagatgta tcgggtagaa gatacgatga gtcgaattgc tttagcttct ggaaatttcc
     2761 gtttggtcag ctatgtcact caaaccggtc tctttattgg tcttgatcgt acctcgacca
     2821 tccgaatgga acaaattacc aaccgttcga ttaatttaga aaaagtagta aaagtaaatg
     2881 atctttcacg taaatatgtt gcttcagagc taacattaga agaactttac tgcgaactgc
     2941 aagcaatcga ccgagaccgt tctttctttc ctgtctggtt gcaaatcgtt agcgcggcag
     3001 tgatcagtgg aacaattatg gtgttatttg gcggaaagat gaccgattta cctgtgactt
     3061 tagtcattgg aggattggga tacgcagctt atctatatag tttgaaattt tttagaatca
     3121 aatttttatc ggaattttta tcttctttat tgattggcat agccgctatc tacagcgtac
     3181 gttttggctt aggaagcaat caggatctaa tcattatcgg atgtgtgatg cctttagttc
     3241 ctggagttca aattacgaac gctatccgtg atttgctagc tggacattat gtctcaggag
     3301 tttctcgcgg aacagaagcg atgatgactg ctacgatgat cggttttgcg attgctttta
     3361 ttttccagct tttttattag gaaaggaaca caagtatggg gacgatattt attcagtttt
     3421 cttttagttt tttagcgact gcggcatttg ccgttattac aaatgtacct aggcgttcat
     3481 tgatttgttg tggtctttct ggtgcttttg gctggatgat ctactggatc tgtgttcaaa
     3541 taggcggatc tgctgctttt ggttcattgc ttggttcttt aggagtagca ttcatcagcg
     3601 atcttttctc taaacgtttg aaaatgcccg taacgatttt caatattccc gggatggttc
     3661 ctctagtccc tggtggttta gcttatcaag cggttcgaaa tctcgttact gaatcctatc
     3721 gagaagcggc tcattatgcg gtccaagcaa ttatgattgc tggagcaatc gctttaggtc
     3781 ttgtattatc agaagtcttt aaccataaca tccgtaattt caaagtaaag cgtgacgcaa
     3841 tcatgatgaa acgaaaaaaa cggcttttta aataaacgaa gtgtaacaaa gaaaaggttg
     3901 tgaaagagac gttcagcctt gagcgatgac aaaatatctc acaaacattg cgacaagtaa
     3961 ccgcaggagc aataagaagt aattatgagt attaaaaaaa gttttgtaaa aatagcttct
     4021 cacattttta cataaaattg acttaatact gagaaactga cttttgaaca ccctctatct
     4081 gtaaaaaagg ggctgcgaca tgatttttgt cacggcccct cttctttatt caaatttttt
     4141 ccaaaacgtt cgttgataat aaacgatcca tagagcggaa agtattagaa ctaaaccgat
     4201 cacaggaata ttcactaacc aaaatggata aaacaaagcc aacattccgt ataagacgat
     4261 aagaataata ctgatgatca atgaacccat catagttgcg actaaaccca aacttcctga
     4321 acctctgtta aataattggt taatattggt ccagttcagc agcagcaacc gataatctct
     4381 agcgaaataa cgtagtgaca ataagtagca gccgaataaa gaaccaaata gcaagctagg
     4441 gataaaaaac aaaggcagct gaaaagacag tccgcttaat aatgcgatcc caccagttaa
     4501 aaaactctgc aatatccatc cgaatctgaa cttttctttt aaatattggt tcatagagat
     4561 tggcaaagaa cggataaaca gaaaattttc ttgatccaaa gaaataagat tgctgataaa
     4621 agaagtctga ttaactgtta agaaagccaa tgcgatccct accaggaaaa caacaccgat
     4681 taacttatta tctaaatcag ttaattttat ttcgcctcct agggcaaaag caagaataaa
     4741 aatgattgga gttaacaagg aagaagaaag aacttgcata atcaaattag gttcttttac
     4801 taattgagca ttgtaactaa ataaaagctg atgcacattt tggttctttt tatgggttct
     4861 ttttattttg aactcactgt ttgaatcagt cagttgctct gtaagctttg gtactatcag
     4921 ctgttttaca gcaaggaaaa atcccagagc cgtgatagct agtattcccc aacccaataa
     4981 accttgttga gaaagtggct gactggcagc atcatagaat ggcaataata tcgaaatcgg
     5041 atgccgatct gttaactcat tttcaatagt ccccgtttga tgattcatcc acatgattcc
     5101 agcaaatgcg atcagcatcg agctgccaag caagatacta gaaactgttt ttctatgttt
     5161 tttaaacact gctgttcgag ccaaaccaaa aacaatcaaa ctagccagac aaaaaagaat
     5221 aatcaaaaat agagaaaaca aaaggattga gataatgata gtaagcaaaa tccctagatc
     5281 agctcgccat ccggttaaaa taaacatgac tagaagcgga aaaacaaaag gaatgatggt
     5341 caaagcaact accaaaatct ttgctgaaaa aacctgttct tgtccaaaag gcagaggcaa
     5401 aaatacttgc aggtcatttc cttcaaaaaa gatattataa atgactgata tactttgagt
     5461 taaacctaac ataccaaaaa gtgccacgta ataagtaaag aaacctggca atttaacaaa
     5521 gttcatagca aacatagcaa atccgtaaat cagtaaaaaa atcagccctg aaaaaagatt
     5581 ttgagacaaa agatagatag ttaatcgctt tccctttttt cctttctctc ttgctttatt
     5641 cgtgagctgt ggattaacat ataaaagatt aactcgaatt aattctaata attgtcgctt
     5701 atacatacgg tccatctcct gtcgcttgcc ttccagccat tttcaaataa atcttttcta
     5761 gcgtttcatc aggtgagcca ttcaataatt cactaactgc cccctgataa atcaattcac
     5821 ctttcttcaa aatagccagt ttatcgcata actgttgtgc ggtatccaat acatgtgtag
     5881 aaaaaatgac tgtttttcct tttgcggcat gagccttcat catttctttc aaatcaaatg
     5941 ctgcttgagg atcaagtcct tgcaaaggtt catccaatac ccaaatatct ggatctggca
     6001 gcaacgtgcc gatcaaaatc gttttttgac gcattccatg tgaaaaactt gcgattgttt
     6061 cattttgatg actatacata tcaaaaagcg ctgtcaattc tgctaaacgc ttttcttttt
     6121 tttgtgtgtc taattcatag gcagctgaaa tcaagtccca atattctcca gccgtcaatt
     6181 gtaaaaaaat atctggggaa tcaggcacat aaccgatttt ttgtttgata ctcaatcgat
     6241 tttccgtcaa tttcattcca tctactaaaa tcgttcccga tgatggttca ataatactaa
     6301 ctaaactttt aatcgtagtt gattttccgg caccattatg tcctaaaaat ccaaaaattt
     6361 ccccttgtct tatcgagaga gacaagtctt ttaatgcttg ttttttcccg taacttttac
     6421 ttacattgat gaattcaatc atttctgtac tccttttgtt tgttattact ttttattgta
     6481 cccttcgtta ttggtggagt aaatgtcaaa aagagtgcat aacaaaaaag gatagaaacg
     6541 actaggctgc tacttgggtt gttctcttct acaggaaaac actcttctaa caggtaagat
     6601 atgagtcttt gttttcttta aaatgattca ttttctatct tttcttgcat aaaattcttt
     6661 agtttatcaa tacttctctt tcccatctct agttgttctc catttgcaaa tgttactatt
     6721 tcgtttactc tgctaataga tgtaatgttt tcagtattaa tgatataagc ttttaaatct
     6781 ttacataaat actcatattc gagtgatttt ttatattttt taattgtgcc gtttacgaga
     6841 atctcttcat ctttcaatac taggcctatt ttatttttat aacctggcat gctcattaga
     6901 taaaggattt catcgtaatg gatatagtga tcgctattac cataacggac agttgtccac
     6961 ctttttttcg tagcatgttg aacaggatag ttttcttttt ctttcaataa gtaactttgg
     7021 atgctttttt tatttttttc ataagtgaat tcttttatca aataaccact aggcgtaatc
     7081 tttcgattaa taacagttat tgctttattc ggatgagacg ttagataaac aattttacac
     7141 ttttcattct tttctctaag catttcgcct agttcgatac cgctataata ggcgttcaaa
     7201 tcgatgtcta ggaaaaaaat atctgaggaa tagatttcat tatttttaat gaattcaaca
     7261 aattgtataa cgttcaatcc ctgaacgatc tcaaatttcc aaggacttaa taaaattctg
     7321 gattcttcca aaatttctac tagcattttt tcaaaaacca aactatcatc caaaataaat
     7381 atacgcgtta ccataaaaag tacctccact cgatatttta ctatcaaaat catttcatac
     7441 aacttttcaa catacatgtt aggaataaat tgtaattctc ttcacaatct tttccaacac
     7501 ctttgaaacc gatatcaaat actttcagga tgctgcttct aaaataaata tcaaacaaat
     7561 gaatacatca tgcaaaaaaa gccagacaac cgacgtcctt gcgtgtcagc tgtctgagct
     7621 atgtttattt attttgttct tttaaaaaga acgatacaca tactgatttt tcggagcaga
     7681 gactttctca gcgtttgtaa caactacaga tgggatttca cgcttgaatg gttgataata
     7741 gtctgattgg atggttcctt ctattttata ccattcatca tttttaaccg ttactccttc
     7801 cggcatatgc gtcaacaaac caaagactcc tgaatctgcc acacaatgga taatgccgaa
     7861 tcggaacaag aagatatctg tattgctatc gttcggtgtt tggtaaacaa atccttcata
     7921 gctgattttt ttgccaatga attcgctagg gtaattataa attagctcca taacttctaa
     7981 atagttttca tctgtgatct tgatagtttg cttatcccca tacttttctt tcaactcatt
     8041 catttggtct aagtagtctg atttgttgaa ataaatactg gtatccggct ttaagtattg
     8101 tgtctgcatc tccggatccc ctactgattc tttacttact gggaaattaa atcctttggc
     8161 ttctacgatc gtagtgtcga gactaactgt tggaaacaac gtccccacga ttactggcaa
     8221 agctagcagt acataagcga ttccacgttg ataaggtttt gacaacccat ggtcatgatc
     8281 gtgctcgtgt gccttttctt ctgcttttcc gtttttgacc cacaaataca gctgaactaa
     8341 agccaaaaga gcagataaaa tcattgaaag aatagctaag tagcgataat ggacattgat
     8401 atattgatcg agtttgccag aaacttgcaa gtacatcatc aattcgaaat acccagataa
     8461 aatcaaaaac cgcagcatat tttccctcct aaataaataa tgtgaatcca ataacgctaa
     8521 gggcaatcag tccgatcagc gataaaataa agcgtcctgt aaaatatcgt ttcatcatca
     8581 gtagattttt gatatcgacc attgggccaa agaccaaaaa ggcagctaca ggtgctgtgc
     8641 cgaacagact taacaaagaa gatcctataa acgcatctgc ttctgagcaa agagacatcg
     8701 taaaggccaa taacagcatg atgataatgg ctaaaatctt tgttgagccg agcgttagca
     8761 taattctagt tggtaaataa gtctgcatcg cagctgcgat taatccgcca atgatcaaat
     8821 aacgacctgt atcaaaaaat tcgtcgattg aatgtgtcaa cacatgccca gtttgatgga
     8881 tcagctgatt ttttggttca ttcttctcac tttgttcttc ttcatggaca tgatgatggt
     8941 gattttctgc tactttagac gtgatttttt ctttcaatac agcgtctttt tgaaaatagg
     9001 caagccagac accaatcaca agggcaacaa aaaagctgcc tatcacccgc cagcttgcca
     9061 tctgccaaga attgccaaat gcgataaaag tggaaaaaat cacgattgga ttgatgatcg
     9121 gagcagtcag cataaaagca aacgctgtgt gaactggtac gcctttttta acaaattgat
     9181 gaacgatcgg tacgatgccg cattcacatg aaggaaagaa aaatcctaag atcgaaccag
     9241 taaaaataga gaagatacga ttttcaggaa gccatctctt cacacgttct ggggtcaaaa
     9301 atacttgtaa ggcgcctgag ataagacagc ctaataatac gaaaggtaat gcttcaataa
     9361 cgatcgataa gaaaatcgta ctcatctgca aaaccgaatt tggaataaaa gaaaacatga
     9421 gtttcctcct ttttatttct agttcattcg ctttgcaaat atacgctttt attcaaaaaa
     9481 aacaagttgc tctgtaaatt tttacacaac tcttattttt taccaaagca cttcaattga
     9541 ctttttctgt tattcccatt aaattaaggt ctcatacata tcacttctat cataaaaggg
     9601 agaataaaaa tgaaacaaac cactaacttg actgaagttc aagacatact gcaacagtca
     9661 tccgttgccg tcatttatct ttcgatgcct aattgcagtg tttgtcacgc tgttcgtcca
     9721 cgactagagg aacttctcac acattatgat attccggcac ttcatttgga tgcatttgaa
     9781 acaccagaag tagctagtaa atttgaagtg ctgactgcgc cagttgtcct gatttttcat
     9841 caaggaaaag aagtctttcg gcaagcacgg ttcatcgact ttaaaaaaat ccgttatcta
     9901 ctagatgaac tgacagcaga agatgattcc ctttcttatg aagaaatctt ccgaacaaaa
     9961 taatcgttgt ccaaacagaa aaaagcgatt gaacaagtga aagttttgcc ttcatttgtt
    10021 caatcgcttt ttatttttat tctgctgtat tttcggaatg cgcatttgcg tcagaatgca
    10081 agaaatagat caaggtttgc aattcattcg tcaaatcaac attttggatc aatacatctg
    10141 acggagcatt caatcgagca gcggtaaagt tcaagattcc tttgattcct gcttccgtta
    10201 actgattgac tacttcttgt gctctttcag cgggtatcgt taaaattgct acttcgattt
    10261 gttggatctt gatttgttct gacatatctt ccattggata aacggggata ccgtctacga
    10321 tgcgcccaac gatttcctca ttcacatcaa aagcacaact gatacgtatg ctattacttt
    10381 gatggaattt gtattttagt aaagcacttc ccaagttccc tacaccgatc agcgcaacat
    10441 ttgtcaattg atcgtcgttt aatgtctttg caaaaaagtg cataagatct tctacatcat
    10501 aaccataccc acgttttcct aattcgccaa aataagaaaa atctcgacgg atcgttgcac
    10561 tatctacttg aacggcttca cttaattcag ttgaagacac ttttttcttt ccagcattat
    10621 ttaaaatcct taaatagcga taatacaaag gcagtctttt agctgtcgcc tttggaataa
    10681 tatgatcttt cacgaaatga cctccacgta ttgtctaatt acatctttga tttctccatc
    10741 atagcagtat ttataggaaa aaatcaattc cattgctcag atattgtgaa attttattct
    10801 ttattcattt atttatcatt tctgcaaatc tcgcagtata atggaattta tggtagacta
    10861 ctaattgaaa aatagttttt tatttgagga gaattcacaa agtagaaaag aggattccat
    10921 gatattatta caagccaatc agattgctcg ccattttggt gcagaagtct tatttgaaaa
    10981 catacattta gaaatcagta caggcgctcg tgtcgcttta gttggcagaa atggcgctgg
    11041 aaaatcgact ttattaaaga tcattgctgg aattgaagca cctgatgaag gaaagatcgc
    11101 taaaaataaa acagcgactc tcggatacct cgctcaggac acaggacttg attccaatga
    11161 aacagtttgg aacgagatgc tgaaagcttt tgaacaagtt agacaaatgg aagagcggat
    11221 gcgcgagcta gagattttca ttagcgaagg tacgccagac acacctgctt atagttctta
    11281 tttaaaagaa tacgaccggc tgcaacacga tttttcagat cgaaacggct atggttatga
    11341 aaatgaaatt cgttccgtat tgcatgggtt taaattcgat tcttcatttt atgatcagaa
    11401 aatcgatact ttatcaggcg gacagcgcac acgtttagct ttagctcgca tgcttttgca
    11461 acaccctgac attttgattc tagacgaacc aacgaaccat ttagatatcg agacactttc
    11521 ctggcttgag aattatctgc aaagctatac tggtgcatta ttgattgttt cccatgaccg
    11581 ttatttttta gataaagtag tcaatgaagt ctatgaatta agcagaagaa aaatgcgcca
    11641 ttacaaaggt aactattcga aatatctaga tttgaaagca gaacagttag caagtgaatg
    11701 gaaggcttat gaaaagcagc aaacagaaat ccataaatta gaagacttcg ttgctcggaa
    11761 ccttgttcgc gcctctacca caaaacgagc gcaaagccgc agaaagacat tagaaaaaat
    11821 ggaccggctg gatcgtcctc aaggggatga aaaacaagca aactttctat tcagtataga
    11881 aaagccttct ggaaatgtag tcttgcaaat cgaagatgcc gctatcggat atgataatgt
    11941 caccttatct gaaccaatca atctagatat ccgtcgtcaa gaagcgattg ctctagtagg
    12001 tccgaatggt atcgggaaat cgacgttgct gaaatcaatc attcaccaga tcccttttat
    12061 ccgtggaaaa gaaacgctag ggacaaatgt caccatcggc tattacgatc aaggtcaagc
    12121 tgatctgcat acaaacaaga cgatcctagc agaattgtgg gatgagcatc ctaccactcc
    12181 agaaaaagag atccgaagtg ctttaggtgc tttcttattt tctggcgaag atgtagaaaa
    12241 accaatccct ctgctaagtg gcggtgaaaa agcacgggtt gctttagcca agttagcgat
    12301 gaacaaagaa aattttttga ttttggatga accaacaaac catttagata ttgacaacaa
    12361 agaagtatta gaaaatgcat tgatcgatta tgacggcaca ctgctttttg tttcccatga
    12421 ccgatatttc atcaatcgga tcgcgacaaa agtcgtcgaa ctctctgaaa atggcagcaa
    12481 agtctatcta ggagactatg attattattt agagaaaaag caggaagaag aagaaatcgc
    12541 cgaattgttg gcacaagatg agccagaatc tgctcctgct cccacgaaca aatctgatta
    12601 ttaccaaagc aaagaacagc aaaagcttat ccgtagcctt caacgaaaaa ttactcaggt
    12661 tgaagaagaa atggcgcgga tcgatgaatg gatcgatcag ttggaacaag aaatggtcgc
    12721 gccagaaaac ctggaagatc acgtaaaact caatgagctg aaccaagatt tagaagctgc
    12781 tagacaagat caagaaacaa aattgacgga atgggaagaa ctaagcttgg aattagaaga
    12841 atatgaaaat taacgaaaaa accaaaacag aaaccattca tgctgttttg gtttttcttt
    12901 ttttatttta tcaaacaaaa attccatatt tacctttttc accaataaga agaccaatta
    12961 ctagtcattc tcactaaagc ttctaaataa tagtaatcac cccaaataca aggtgtattt
    13021 accccattat ttttgggctt attataaaca gactgtgtta aaaagccatc ttcttcttcc
    13081 gttgtagcat atctttcttt caattgtcgc ataattttcc aaacagcaga ctggtataag
    13141 ttcttttctg ttttgtctaa tagacctgat tctattaatt ctaataatcc acaaaccatg
    13201 atcaccatac tagatgtatc tttttcttct ctgctagaat catcaaagat caaatcccaa
    13261 taacaaatgg tatcttctgg caaccgattc ataaaataat tggctaatat tttgcttaaa
    13321 tcaaaatatt tttgttcttt caaataacga taacttaatg caaaaccgta aatcccccat
    13381 gcttggcctc tagcccaaca ggaattatca ctataacctt gatgcgtact tccatatctt
    13441 ggttttccat ctttgacatc catataaaat gtatgataag ttgaaccatc ttctcttact
    13501 aaataatctg ctgcattttg aatatgagcc tgagcagctt ttttatattt ttgatttcca
    13561 gtttcttcac tcgcccaata caataatgga agattcatgc aacaatccat gatcattcta
    13621 ccttgttgtg aaggatcact aggatctccc caagcttgta taactcctgc cttctcccaa
    13681 aaacgctgaa gtaatgtttc tgcagcatca attgaagctt ccttcatttt tcgatttccc
    13741 gttattttat aatctgctac ggttgataaa gaatacaaaa aaccaagatc gtgatgatta
    13801 gtgataattt gacagtcaat cctgtggata aaatctatat ctgctttttc agctgtttgt
    13861 tgaaataaag gatcacccgt cttctcaaat aacaaccaat taattcctgt ccaaaatcct
    13921 tctgtccaac caatattgtc tcttaatgga taacgtcctt ttataggaca ctcgcttggg
    13981 aattgatact gactgttact gatacgtttg attaacctct ccgtgtgtct gcgacaacgc
    14041 tcgatctcat tattccattc tttttccatt aattctttat aacattcatt tatccatttt
    14101 tctggatgta ttatctcttc aaacatcact ttatcaagca tttccccacc agcctttagc
    14161 ataattttag tcttttttta ttgtttttat tttggatagt tagcccggtt gtcccatcaa
    14221 aatcaatttt gggacgattg ttccatactt ctaaactata atcccgatct tgatgagcaa
    14281 ccactcctgt tccgagccaa tgggttcctt ttccaaatgt accctctaat ccaggaataa
    14341 aagtgttttc ccatgtcatc aagtttgtat tgggcaaacc cataatagct gtggattttc
    14401 gtttaatagt atcgtcactt aaacagataa tacctgaaaa gccagcttca ctcaccctat
    14461 agttttcctt gtcttcttct atgattattc cttctttctc aggagaacat tcaatagcaa
    14521 accctgtctc atatagaaca tattctgtat ctaattctac tttgtgtacg cgaatctgcc
    14581 agccttcaaa aggaataagc caagttctga tttttgcctg taaagtaggt tcccatgtag
    14641 aggcaagtac ctctttctta catacaatgt ctcgtacatt atttcgaacg atgaactgtc
    14701 cataggtttt gatgctctca ttcttaaaac tggtcgtgat atatgtgtcc gctcgctgaa
    14761 tccctagcat tgaatccatt gccatttctg ctttcaattg attcgctcgc ggtatcgaaa
    14821 aaccaaattg actagaataa gcaaatttta aatatttttc attggtcaat gtatggaaat
    14881 ttggccctaa ttgtcccgca ttcaaaaaaa atgtatgtcc attatcatgt tgtatgagca
    14941 aattggcttc tgaaagaagt ttagttcctt cacgaatagg cataggcatt tctttagccg
    15001 tccaatactc atggtcttca ggtagcgcca acaataaaaa aatcttattc agccataatg
    15061 gagataacgt actattatag ggttcagtca atgtcaattg agggtaggta taaccaatat
    15121 tcaggatacc tttttcatca aatatttctt tttgcatcca ccatcttata ttccgattga
    15181 ctaacccctt gatttcacct aatttaaaag gcaaaagatc ggcccacaac atagctgacc
    15241 aaaagcttga aactgcaaaa cgataaatca tgcttcgacc aaaaggcaca tttgcaccat
    15301 cttccgcaaa aaaatgaata tagtctctag aaaaatcaat agctcggttc ttatatatct
    15361 ggctaatggg cttttctggt tctagtacgc tataaatcaa accataataa tgaaatgcaa
    15421 aaggattata ataatcttgg cgacctcttg aactgtctcg ataccagcca ttttgaagat
    15481 aacaattttc tatattatca aatgcttctt tcagtgctga ttctttaact ggataaccaa
    15541 atttttggat aattgttccg acaattatct taaaaaattg ccaattacca tctgcacatt
    15601 catattcaaa aatttgcgag aaccaatgaa taatctggct tttttctcct gtatctaatt
    15661 ttttccataa taattgttca tgatgatata acgctaataa cattgcgggc atttctacca
    15721 tacgctggtc tctttcatgt atttctcccc aataatcggg atgggaagga tctgttccag
    15781 cttttattcc tgatagaatt aatttcaacc atcgttcatc taattggtca attgcgggcc
    15841 ccgctcccca taaaacccga gagaatcctt ccattcctgc aattttattt ccatatccta
    15901 ccccttgatg tatataatca atttgtgcgc cacttgctcg ataaaacggc tggagtggtt
    15961 gatttatctt tttaaataag tcaaagtaat cctgtctggt ccttaatagt ggtactggat
    16021 gtttcattgt attttctcct ctttttacta ccaaatagct aattccgact gttctaatcg
    16081 aagtaagcct tcaataaaaa aataatcaga atagatcagt ggcacattat aagtcagttc
    16141 tctatggtat gcttctgctc cgcctccaat gatcccatct tcatccatat tccaatttgc
    16201 atagtgcttt tctgtctttt ggagtatatt gatagcagct tcatgataca tttttgatcg
    16261 tacagaggaa acatatcctg ctaattccag aagaccgcat gcagcgcata ctccagcact
    16321 ggtatcaata ttcgaatctt ttacagcaaa atcaatgaga ggaatataac cagttttttc
    16381 gattttctga ataaaattta ctgctatctt ttctgctata gctagatagt acggattttt
    16441 tgtgtaacga taacttaacg cgaatccata taaagcccat gcatttcctc tgctccaaca
    16501 agaattctca ttgtatcctt gcccgccaag taaccgaata tatttccctg attctgcatc
    16561 aaattctgcg atatgcccgg ttgatccatc tttcctcact agatacttag ctgttgtatc
    16621 tgcatgctgc cgagcaattt tagagaacct cggatcacca gtttccctcg aagcccaata
    16681 cagtaatggt aaattcatca tactatcaat aatcatccaa ccaggtttat ggtcattcca
    16741 tgctactaaa tagttccctg aaatattata gcgtccagca agtaccgtag ctgcatgtaa
    16801 ccctagttgt cgactatgtt tgttttgaga ctgttgataa tgtgcaatag ccgatggtaa
    16861 gaataaaaaa cctacatcat gatgaacgtc tgaaaaatgg tacagggcag attctaataa
    16921 ttgttcttgt tgtattgctg cctctttgaa cttttctcgt tttgtcttgt gaaagagctg
    16981 ccataaaata ccactccaaa aaccattggt ccaccagtcg attcctctgt cctttattac
    17041 gtctgtatat tttccgttgt aagaaatata tggaatttta ttccccattc tgtctaattc
    17101 cgcatctatc ttttcagaag ctacattcaa aatttttctt gaccattcct tcgtctgttc
    17161 attcatggat atcccgccat tcttttaatt tttatgaatg tggagttgct cctagaacga
    17221 actagatggt taacattcgt tatttttttt acttatttgc agctccaatg tcattctcct
    17281 taaatttaga ctgcgcccac acataaatca agaccattgg gatcactgaa gttgctaaaa
    17341 ttagcataat tgcgccataa ttaattggct cacctgtact agaaaccgtc atatttttga
    17401 taattaaggg aaccgtatat ttatctttat ctgaaagcat gactaatgga aatagatatt
    17461 gattccaact tcccataaag ataagtaaac cactagtaat aatcgtaggt gataaaatcg
    17521 gtacagcgat tttcgtaaaa atcacccact cattggcacc atcgattctg gcagcctcca
    17581 tcagtgctgt aggaaattga ctgctatatt gtcgcatcat aaacactgaa gttgtactgg
    17641 caatcgaagg gatgatcaca cctgcataag tattcgataa tcctaaacga ctcataatgt
    17701 aaaataaagg aatcaatgtg gtaaaaaaag gcaccatcct agatagcata actgtattga
    17761 acaacagttt attccccata aaacgatact ttgctaatgc ataacccgcc attgtagaac
    17821 tggctgtagc tgaaactgta ctgattacag caataacaat cgaattccaa ataatcaagg
    17881 gataattata tctcgccatg atggcttgcc agttttttaa tagcatatcc ccaaacttga
    17941 aattgattcc gccacttaaa atttcttgat tactttgcgt tgaagctaca atcatatata
    18001 aatatggcat caaaaatatt aaggcaccaa acacaataat gacgtacgta aaaattctgc
    18061 tttgtatctt ttgtttagtc atttttatca cctccgaatt taaattgaat agccgataat
    18121 ataacagata caaacaccat cgtccaggca atagcagagg cttttccaaa atcaaccatt
    18181 tcaaaacttg ttttatataa attgactcct acgaccaaag ctgaattttc tggtccattg
    18241 gaagtcccaa agaatatatt tgggatattg aaattaccca agccattgat agtggctaaa
    18301 actgtggcca ttaaaatgat tggctttagc atggggatcg ttaataaaaa gaattgccga
    18361 aatttcgatg ctccatctat ttcagcactt tcgtatatct ctttagaaat cccttgaaga
    18421 ccagctaaaa ataaaatagt gttatatcct acactaagcc aaatcatcgt gatgatcatt
    18481 gatattcgta tccaaaaagg atttgttaac cactgtacac cgttaattcc tagcgcattc
    18541 aaaaatccat tgaataaccc agtcggattg aaaaaagtca tgaatacgga agctacagcc
    18601 accgttgatg taatggttgg aatataatag acagttctaa aaaatccttt tccttttaac
    18661 tgtgctgaat tcaataaaac agcaaagtaa atagctaata gcatcgttat tggaattgat
    18721 cctgccatga taatcaaaac attcgtgtaa gatttaataa acaatggatc tcggaagata
    18781 gctagataat tgtcaaatcc aacaaattca aatgagtagc caattttcat aaaactaaaa
    18841 gcaaacgaga taatgatggg aatcaaaatc gtcacaataa agaaaataac aaaaggtgtg
    18901 accaatccat aagcactttt tttatgagac gtatctgttg cttttttctt gctgttcttt
    18961 attgtcttgc ttggtaacga agattgcatc atcgttaagt cctcctaata ttttttaatc
    19021 accagttaat tttacgccgt acttatgagc aaaattttct gcttctttta gatatgaatt
    19081 ttcaaaatca cctgtttgcc aatagttata tgcagcggta gtcaaataag acgtagcatc
    19141 tgaataagtg gctggtaaaa cagtatttga tgtattttca ttgattttat tcaatagttc
    19201 atagtatttt tgtcctcctt agtagtcaaa ctttttctca gctgcttctg tttgataggc
    19261 caatgagtta gatgtagcca cgcccagctc cagtgcgttg gctaagcatt cttcatctgt
    19321 cagcataaat gtaagaaatt gttgtgccac ttgtggattt ttggcatctt tagggacata
    19381 aaaacttgat cctcctgata ctgcaccttt tcctggattt tcttttgaaa aaggaatcag
    19441 tggagccatg cgccatttgt cagatgcatc aggaaaattc aaagacatat tcgtagcata
    19501 ccagccgcca gcaacaaaca ttgcagattc ttgaaatgct ttctcagcat cttgtgcacc
    19561 gtagaaatgt acaatatctg agtcgatcat ttctttgatt aactttgcag catgtttcgc
    19621 ttctttagta ttcagacgga tatttccttc ttcatcaagc aaagattgat tctgctgggc
    19681 tagcatgttg ataaacaatt cttggtcccc agattctggc aaggcaattc caaaactacc
    19741 agttttttct tttaatgctt ttgccacctg gatatattct tcccaagaac tgatttcttc
    19801 aaaatctaca cctatttcag caaatttttt tggttgataa taacaaagtg ctggggtaaa
    19861 atcactagcc caaggaataa tcgtttcatt actcgtttgt tgacgcaaaa tattcaattt
    19921 ttgatcataa aactgatcgc catatttgtc ataaaatcca tattcatcag cactataaaa
    19981 agcatcttga aatttttcca gcacacctgc tgctgaagtg tctgccatgg agataatatc
    20041 cggcatatct tcgtgtgtta ccaattttgg ggtgatcatt tgtactgttg ctgttcccga
    20101 agctacattc acaattttta agtcaatatt tgctccagtt ttgcggttat agatttttgc
    20161 agcattttca acatagtttg tcagtttgcc gtttgcgaca tatacttcta atgtagtggc
    20221 tttttttatc attggatctg cgatgtttgc tgttacttct tcgttagttt ttccacatgc
    20281 acttaagctg aataataggg taatgtttag caaagctatc accaatttgt atcttttttt
    20341 catgtctatc ccttctttct tttcaagttc ttatataaaa cgctttcact tatgtatatt
    20401 aacggaatta gtaacacaaa tatttatata aaaaaatatt ttacttgtcg ttttggcttt
    20461 tcatttttgt tataatagtc attaattata aatagaaagc tttttatata aaaagagaaa
    20521 ggaaagtggt tcttttgtta acaaacaacc aatcctccaa tcttgtcaaa aaaacactaa
    20581 cctattccat agatacccat cttcatttat ctgctgctcc ctattttcga ctactaataa
    20641 atgaaagcgc taatttatat gctgaatttg cacataaatc tatagaacta gataatcctt
    20701 cccttttatt cattgataaa cagcaagaag tccaaatctt ttctactcaa aaggaaacac
    20761 aaacttttat cattatccag ttttattttg atgagcaatt attagcacat attacgggac
    20821 aatctttttc tatagatcaa gaaataacat ctatcattac ttttctgaaa aatgaacagt
    20881 tcaaaattga ttatctaaaa catagtaagc cagctatttc ctatgatcag gaaatcaatt
    20941 cttttttcat actatgccaa cagatgagca ttcatttgct ttccttatta gttacttatt
    21001 gtctgcaaaa aattcaattg tcttccttac caaggcatta tcaacaggaa cttgctttat
    21061 tgacaatacc ttcaaatgag aaagtcattc ctaaaaaaaa gcatattctt tattcagatg
    21121 aattagttga tccaatcata cgatatttag aagaacatct ttcagaaaat tttttgcttg
    21181 aacaattagc ccaaattttt tttatcagtc cagccagctt aaaaaaacat tttagaaaag
    21241 tgaatggaaa aagtgttatt agctatttta aagaactaaa aatggaaaaa gcaaaacgtc
    21301 tcgtgctaga aaatgaatta acctatacag aaattgcaga tatattagga tttcattcga
    21361 tccatcattt ttcttcagct tttaaaaaat atacagggtt atccccttca aagtattatc
    21421 tatccttaaa atagaaaaaa atttttaggt tttatccaca aattatttct ctatattttc
    21481 tgtctattca aaataaacaa taattttccg gcacaattat ttgctgtttt ttaccataac
    21541 atagtacgat caacgtagaa aaggagatgt ttttatgaaa gttgttgtca ttggcggtgt
    21601 agctggcggt ccttcatttg ccactcgttt ccgtcgattg aatgaagcgc acgaaatcat
    21661 tatctatgaa cgcggagaaa atatttctta tgcaagttgt gctttgcctt attatttagg
    21721 aggtgtgatc actgaccgtg actcgctgat cgaacgtaca ccagaaatat tgaaaacaaa
    21781 aaacaacatc gatgtcttta ctaaacacga agtaacagca atcgatcctt ctactaagcg
    21841 attaacagtt aaagacctat ccacaaatga agaaataaaa acagattacg ataagttgat
    21901 catctcttct ggtgctagac cagattatcc ggatattccc ggagtttttg aagcagaaaa
    21961 cggctttgtc ctccgtagtg tgacggatgc ggatcgaatc aaatcgttcc ttgaagaaaa
    22021 aaatccacaa catgtcgtca ttcttggtgc aggtgttatg ggtctggaat tagctgagaa
    22081 tttcaagcat cgcggcttag acgtgacttt aatcgatcaa ttgccacaag tcgctttccc
    22141 ttatgatcca gaaattgcta atttagttta tgacaaattg ctgaaagaag gattagccgt
    22201 tcatttagaa acaagagtta ctgagatccg tgataaaggt cgagaaatag tattatcaga
    22261 tggctccgtc ctttctgctg atatgctaat ttttgctgtt ggtgtttctc cgaagaatga
    22321 agtggtgaaa gcaaccggca tacaattatc agatacaggt cagatcattg ttgatgacca
    22381 gttacaaacc aatctgccgg acatctatgc gattggcgat attatcgaaa cgactagtgt
    22441 agtgactggt cagccgatcc aaagtatgct ttccagtgcg gccaatcgtc aaggacatat
    22501 gctggcagat attttaaatg gtacgcctat gcgctatcgc ggatatattg gtgcaggtgt
    22561 cgcaaaaatc tttgatcata cagcaagtta tgcgggaatg acagaacatg aattaaaagc
    22621 atcaggcata acaaattata aaactgtttt tatcactccc tttgaccatg cctatttcta
    22681 tccagaagct acaagattaa atctaaagct gatttttgat gcagatagcg gtcgtatttt
    22741 aggtggacaa gcatttggag aaaaaggtgt cgataaacgg atgggagaac tttctgtagc
    22801 aatcaccgga aacttgacag tctttgattt gcctgatttg gagttgcctt actctccacc
    22861 gtattctact acccgtgacc cgttgaatat agctggttat gtcgcaatca atcaaatgac
    22921 gaatatcgta gaaacgatca aagcaagtga tatacccgaa aacgatttga aagaagcgtt
    22981 ctttttagat atacgtgaac ctaataaagc accttctggc agtatctcgg caacaaaaaa
    23041 tattccaatg aatgagttac gagatcgaat caatgaaatc ccaaaagata aaaaagttta
    23101 cattactttc agaagaggat tgaataatta tacttctgcc cgaatcttgg caggtttggg
    23161 tatcaaagcg attttgattg aagaataaaa aaacgaccgc ggtgggtagc cgcggtctag
    23221 gagttatttt tacttgagga gtaaaaatga aaaagtatat agggttgttg gttggtatgt
    23281 atatagaata gaagataaat gtgaagaaat tgtgcattat ttcttcacat ttattaggtt
    23341 atagtttaag aaagtttaaa cattgcgcaa tttaattatt ttagctgttt cttttcataa
    23401 aaaaacatgt tgtgactctg agacaaatca tagtccatag tgatgtctct agagtaacta
    23461 cgcctaatat tacgaggcat catattaatc tatcagcact agtacctaaa ctagcatccc
    23521 tttcgaatat tttttcttat ataataaagt ttgctttcac tcctctaatc tcaccaaatc
    23581 gactggcttg cgttgtgtga tactaggaac tgattggttt agaacgactt ttctattgta
    23641 atcatatttt tcgccatcct cgttgtcttc taatccttca atgaatgatc cctaatgtgt
    23701 gtattaaata atttaatttt tttgttccta tttatttaac
//
LOCUS       DAXLPY010000041        22692 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.041, whole genome shotgun sequence.
ACCESSION   DAXLPY010000041 DAXLPY010000000
VERSION     DAXLPY010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.041"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(34..477)
                     /locus_tag="ACF3UF_001721"
     CDS             complement(34..477)
                     /locus_tag="ACF3UF_001721"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3671832.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(493..1653)
                     /locus_tag="ACF3UF_001722"
     CDS             complement(493..1653)
                     /locus_tag="ACF3UF_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3671833.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTIAEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            2529..4229
                     /locus_tag="ACF3UF_001723"
     CDS             2529..4229
                     /locus_tag="ACF3UF_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671834.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNIRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFNKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKHLRA
                     "
     gene            complement(4331..5164)
                     /locus_tag="ACF3UF_001724"
     CDS             complement(4331..5164)
                     /locus_tag="ACF3UF_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFD3671835.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLAKKTLESQVLTVSQSQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEEGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(5714..7879)
                     /locus_tag="ACF3UF_001725"
     CDS             complement(5714..7879)
                     /locus_tag="ACF3UF_001725"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFD3671836.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNRQADS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLEVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            8139..10433
                     /locus_tag="ACF3UF_001726"
     CDS             8139..10433
                     /locus_tag="ACF3UF_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFD3671837.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFAGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEATITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            10426..11091
                     /gene="pgmB"
                     /locus_tag="ACF3UF_001727"
     CDS             10426..11091
                     /gene="pgmB"
                     /locus_tag="ACF3UF_001727"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFD3671838.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDRTFNEQLK
                     GVSREDSLSLLLAHGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            11084..12091
                     /locus_tag="ACF3UF_001728"
     CDS             11084..12091
                     /locus_tag="ACF3UF_001728"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFD3671839.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEELPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRKMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            12113..13132
                     /locus_tag="ACF3UF_001729"
     CDS             12113..13132
                     /locus_tag="ACF3UF_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3671840.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDPVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(13413..14780)
                     /gene="nhaC"
                     /locus_tag="ACF3UF_001730"
     CDS             complement(13413..14780)
                     /gene="nhaC"
                     /locus_tag="ACF3UF_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFD3671841.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(14889..16310)
                     /gene="tyrP"
                     /locus_tag="ACF3UF_001731"
     CDS             complement(14889..16310)
                     /gene="tyrP"
                     /locus_tag="ACF3UF_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFD3671842.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(16553..18430)
                     /gene="tdc"
                     /locus_tag="ACF3UF_001732"
     CDS             complement(16553..18430)
                     /gene="tdc"
                     /locus_tag="ACF3UF_001732"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFD3671843.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FTDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(18721..19977)
                     /gene="tyrS"
                     /locus_tag="ACF3UF_001733"
     CDS             complement(18721..19977)
                     /gene="tyrS"
                     /locus_tag="ACF3UF_001733"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFD3671844.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEVEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(20089..20294)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20557..21858
                     /locus_tag="ACF3UF_001734"
     CDS             20557..21858
                     /locus_tag="ACF3UF_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD3671845.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(21927..22526)
                     /locus_tag="ACF3UF_001735"
     CDS             complement(21927..22526)
                     /locus_tag="ACF3UF_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3671846.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT         6857 a         4703 c         4062 g         7070 t
ORIGIN      
        1 taggctggga gcattatttc gttattctgt tcatcaaaaa tcagcgtttt gattccattt
       61 catcacaagt tcctcctcat ttactgcttc atctttttgc tgtgtttgaa ttgtaaaacc
      121 ttgtgaaaga tagaaatgaa tagctgattg atttttttga tagactgtca aagtcagtgt
      181 tttattggtt tcttttattt ttttcattag ttgcgtaccg attctttgtt gccggtattc
      241 ccttttcaca aagattcctg cgataaactg atcaatcacc ccagcaaaac caataatttc
      301 ttgatctatt tctgctaagt aaatcactgc atctggtaaa gctttcctaa cagattctac
      361 ttgattctcc caataagttg atggaatgaa ttcatgagaa tccaagttag catgtagcca
      421 aatcgataga acagattcca gttctttggc agacaatttt gttgttgtgc ggatcatttt
      481 ttctctcctt acttattcat tgattttaaa ataaaaacca tttttttgaa gctcttttac
      541 aagttttcgc ccctcaaaaa agtatatctt ctcttgtttt acttttctaa taccaaaaga
      601 aacagcaact ttaggatcat cagctgaaac gattcgataa gtcccaccag gcaattgatc
      661 cagcttgact ttcccatgat ggtcgctttg tactgaaaac ggcacaccat ttctagtaag
      721 tgtttttttc ttatgtttca aaatgaatga actaccattt accggtttcc ctgacgaatc
      781 actaataata aatgaaaaat caagcacttt tttacttaat ctatactgat agattagtcg
      841 tccgataaac actaacagta tgactacagc tattatcgtt cctgcaagaa taaaccattg
      901 ccgcatggtt ctttcctgat ttccttttcc ttcttctttt tttaccgatt cgttataagg
      961 aatccgatgt cctgtcacta gcaaacgatg cgtgttgatc atatacggcg tacatgtaag
     1021 caaggtaact aagtcttctc cttctgcaat cgttagaaca gacgtgtcat ctggcagtac
     1081 cacttgtata tttttaactt gataagccaa tttctctccc aaaacagtca aaataaacgt
     1141 gtctccgttt tctaaacgat ctaattcggt aaataaccgt cgattaggta aaccgctgtg
     1201 agcagagatc actgaatgcg tcgaatttcc accaagcggg aaagaggttc cttgcaagac
     1261 gcctgctcca ttttcaagga tcctaccatt gagccgatca taaagtgaaa tatttaattg
     1321 gatcttaggt atattgatac ttccgatcag ccattcctct aattggctgg atgttgtact
     1381 ttcatttctg ttcttttcat tgaaaggatc agtaccagga ttgaatcctt ggtcagttaa
     1441 tcgttggttt ttctcctcca ttttctttcg ctgcacttca atttcagctg cggtccgttt
     1501 ttgtacttgt tcgatacgtt tttgatcaat aaaactattt aaagaatcca cataaaatgg
     1561 atataaagcg atcagtaacc ctacgacgat acatattaat aaaaacaaac gaaacaaaag
     1621 tcgacgagac tgtttttgct tactctgctt cacatgtgtc ctcccttgca agtttttttg
     1681 ttctttcttt tattatatgg gttcaggaaa aaaatagaaa atgaaagccg atgagattgt
     1741 gaaaaagctg tcctgcatca agtaataagt acagcctcaa aaaatagcta ctcatatttt
     1801 ttgttgggtt gggcttatta ccgcagatgc aagcttttga acaccgttta aggaagaggt
     1861 tgtgaaaact gcgttatgct ttgagtaata agagtgctag tcagaaaata gcttctcata
     1921 ttttctaggc tagtgagctt attaccgaga agcagctgat tgaacaccat ttaaggaaga
     1981 ggttgtgaaa actgtgttat gttttgagta ataagagcgc tagtcagaaa atagcttttt
     2041 atattttcta ggctagtgag cttattaccg agaagcagct gattgaacac cgtttaagga
     2101 agaggttgtg aaaactgtgt tatgttttga gtaataagag cgctagtcag aaaatagctt
     2161 tttatatttt ctaggctagt gagcttatta ccgagaagca gctgattgaa caccgtttaa
     2221 ggaagaggtt gtgaaaactg cgttatgttt tgagtaataa gagcgctagt cagaaaatag
     2281 cttttcatat tttctaggct agtgagctta ttaccgagaa gcagctgatt gaacaccgtt
     2341 taccgagagg tcatgaaaaa gctactttgt ttcgagtatt aagaaaaatt ctgtttcaaa
     2401 acaaggagat gcaacaaaac ttatgtcgca tcctctctcc ttagaacttt cacttatgtt
     2461 tttcttgtaa aattcataaa tattttcatg aattttctaa tttcttgcct acctctcgca
     2521 taggatatat gatgaattta tctaaagttt gcaaaggagt tcgacaattg aaaaaatatg
     2581 gcccattttt agcaattttt ttcattgctt tggcatttct catgcctcat ttattcacac
     2641 ataaactaat tttgggtgct gatgccccat tccattacaa tcggttctat gatgccgcgc
     2701 aacaaattaa atatggggat ttccattatt ttccttccct ttatggattc cagcaaagtg
     2761 gcaggatcgt gaatgccgtt tacggcccat ttttcgctta tttacaagga ttgatcgtgt
     2821 tgcttgcagg tagctggttt cattatcaga ttctttcaaa tttcattctt tatcttattt
     2881 caggattttc tatgctgatt ttactgagat atgtcaatat tcgaaattgg gtaagtgtac
     2941 cagtagccgt tttattcatg agtacgtatt ctattcaata ctggtctatc aaccaaggat
     3001 tcactagctg ggggacttgt ttttatcctt tatgtatgat ccctattgct gatttcgtcc
     3061 ttcataaaaa gtttcctgtt atcaaagtcg ctgtctcagt gggacttatg acacagatcc
     3121 atttactgtc ttcgatcatg ttagctttga tgtatattcc tttttatctt tattactttt
     3181 ttaaccagac tgaaaaagga aaagcactgc ttcaactgat taagtcggtc ttgctttatt
     3241 ttgttctgac agcaaatatt tgggcaggat tagctattgt ttacagtggg aataagattc
     3301 ttcctccctt tgttaacaga gaaatgagtc aaaaggcgat agatctggat ggcagttatt
     3361 ggctccatta ccctaaggcc tttcctatat tgatattatc aggttttttg ctttttattt
     3421 tctttcaaca aaagaacacc ttattccaaa aaatcgtgtt gtacacaagt cttgttttct
     3481 tttttctttc tactagcttg attccatgga cgacattgat cgaaaaaaat gtgcctttta
     3541 ttagtttgat ccagtttcca tttcgatttt tcgtgccatt tacgctattg cttctacttt
     3601 accttgccct ttcactgaac cagtggtctg aacaaaagtg gttccgtctt ttaagtatat
     3661 ttggcattct tattttttca gcacagacga tccagaactt ataccagcat ctggaaaagt
     3721 gggaaaatga aacatttgtc agtcgacata cttatctatt cgatacgccg gaagaagcaa
     3781 ggaaaacatt cttcaacaaa gatatgtcta ccagcttgtt cgttttccaa aaaaccacac
     3841 ctgactatct gccaatctat aaggagacaa aagacaataa atacgaccgg tataacgaag
     3901 aaatactaga aaacgaaaca acttttataa aaacacatcc aggcggtctt ctgacaatca
     3961 agtggaaaaa cactggggac aaaactgttc atatccctgt tatcgtctac gatcggactg
     4021 tgctacagca aaatggaaaa acattgactg attatgaagt aacagatatc gggaccccaa
     4081 tcgtgaagca gcaaaaagga atcaacgagc tcacgcttca ttatcaaacg ccaatctatt
     4141 tctatttcat tctttctctt actttgattg gctggtttac cttgctatgt ttatttattt
     4201 atcatagata caagcattta cgtgcttagg caaaagggat aaatgcatcc gatcaaaaaa
     4261 ctctccaaac ggtataatcg tttggagagt tttattttaa tcagtttttt tatgttatat
     4321 gttatatttt ttattcgttc acatctaatt cgatttccac cccgtagtga tcactgatga
     4381 ttggactatc gatcccatca aaaatccgtt gatatttttt aacctgcatt ccttcaggga
     4441 cgaaaataaa atctatacgc aatttttctg tattttgttc ccaaccatcg attttctttt
     4501 ccacagtagc tgcttttcct tcttcattcg cgacaacata cgaatcttga agaagaaggc
     4561 aactttctct tacagtataa taaccttgag agtctactgg attattgaaa tcacctagga
     4621 aaaaaagtgg tacgcgagtt tccaaaaagt agttttccaa gtttttccac tcaaaataaa
     4681 agccactttt tttatctgtc caccaagaaa agtggcagct cgagacaaaa atgtcctgat
     4741 catctatctt tgttttccca atcaagatct tgcgtgtctg ataatcttct ttcttttgag
     4801 attgggagac ggtaaggacc tgactttcca atgttttttt cgcaagcagt gcatttcctt
     4861 cttcatattt atcataaccg atgtggctca tttcccaact ccaaaaatac tcttttccgt
     4921 gttcctttaa aagctgaact aaacggtagg caaaattatc tttacggata ggtacttgat
     4981 tctttaccgg acagaacttc attagcttcg caggttctac ttcttcagat tccagtaatt
     5041 ggttgatttc ttgtaaagca atcacttcat aatcttctaa caggatctta tctgctaatt
     5101 cttgcaattt tttctctggt tctggctcaa gccagctatg cgtgttgagt gtcatgaatt
     5161 tcattggttt tctccttgtc ttcatttcga aacaaaaggg ttgtgacaaa atttttgtca
     5221 caacctctcc agcaaatagt gttctcctgc taactcctca gtaataagct caatggacca
     5281 ggagctattt tttgtttggc tgtttttatc acttggtgca gggcagcttt ttcacgacct
     5341 ctccactaaa cagtattcaa actgctgctt ctcggtaata agctcactag cctagaaaat
     5401 atgaaaagct attttctgac tagcgctctt attactcaat gcataacgca gttttcacaa
     5461 cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa
     5521 aaataggagg agctattttt gtttggctgt tcttattact tgatgcagga cagctttttc
     5581 acaacctctc gataaatggt gttcaatcag ctgaccttag gtattagttc aaaaaacggc
     5641 aaaatacgag gagctgtttt ttcgttttgt ttctctaata ctcaggtcag gacaatgatt
     5701 tcacaacctc tccttacatt ttaatggagc cgatcacttt accagctgtc actgtaccta
     5761 attgcttgat cactacttct tctactttat cgtttgtaaa tacgatcatg atcgttggat
     5821 ctttttcttc attttggatc acctcaagat ccatctcagc taatttcgtt cctgttccta
     5881 cttcttggcc ttctttgaca gcaatctcaa aagctggctg attcatttgg actgtatcga
     5941 tacccatatg gatcaaaact tcgataccat ctttcgtctc cagcccaatt gcatgtttgc
     6001 ttgggaaaat acttgtcact tttccagcga tcggcgcaac aacttctctt gatgttggaa
     6061 taacagcaaa gccgtcaccc atcatttttt gtgagaatac cggatctttt acttcagata
     6121 aaggaatcac ttctccagaa gctgcggaaa ctagttcttg ttctatacct aagtattgct
     6181 tactatctgc ttgtctattt cctgtagaaa ccatttctgg ctctggaatc tctgctcctg
     6241 attgcagcag atcttcgata tctgatttca agacatctgc ttttggtcca taaactgctt
     6301 ggactccatt gtctttgacg atcaatccca tcgcccctgc tcgtttccag gcttcttcag
     6361 tccctacttt ttctcgatca tttacactta cgcgtaaccg agtcatacaa gcatcgacat
     6421 ctttgatatt ttcttttcct cccagcaaat gaatgatctg gaccacttgc tgatctgctg
     6481 ttcctgttcc gctgttagat acaacggttt cttcactgtc attgtcgtaa tttccgttac
     6541 gtcccggtgt agcaaagttg aattttttga tcaagaaatt tgctaagaaa tacgtaacaa
     6601 caccaaaagc gatcacacac aacacgaagt tgataagatc tccacctaaa cccgctttga
     6661 tagctaacgg tgtccgagtc agcaattcga tattcccaaa tgaatggacc cgcaatggca
     6721 agatatctgc catcgcaaat gcagcccctt ggatcactga ataaatgaca tataatggca
     6781 cagcagcaaa cataaacatg aactccaatg gttctgttac acctgttaga aagacagcca
     6841 acgctgctga aaaatacatt gatttatatc ttgctttctt atcaggatcg acattacgat
     6901 acatcgcaaa agccattccc atcaagatac ctgaagaacc aatcatttgt cctactttga
     6961 aacgagccgg cgtccagtta tgcaacacaa actcatattg cgacatatcc cctgcacctt
     7021 taagattcac taaatcagtg gcccaagcca accataacgg atcttgccca aatacttgtg
     7081 tccccgcctg tgcgcctgat aaaatctcat acgatccgcc aagctgtgta tagttgatag
     7141 gaatcgtcag catatgatgc aatccaaatg gcaatagtaa acgttctaat gttccaaata
     7201 aaaacggtgc tagaatcggt gcgctttctt gtgattctgc gatccataaa ccaaaattat
     7261 tgattccagc ctgtacgttt ggccacacca cagcaagaat caatgccacg attgttgacc
     7321 ataagataac aacaaacgga acaaagcgct ttccattgaa aaatgacaaa gcatccggca
     7381 attttctata attatagtac ttattataag ccattgcccc gacaaatcca gcgatgatcc
     7441 ctacgaatac tcccatattc aaagctggtg cttccaatac acttgtaaaa aatcctttaa
     7501 ccatgatctt cgtaccgaac agagtgtggg taaatgcatc ttcattcgca agcatgtcac
     7561 ttgtgacacc aaagatagcc ccagtgatcc gattgatcaa aataaatgag atcccagctg
     7621 caaatgctcc gcctgctctt tcttttgccc aacttcctcc tattgctaaa gcaaataaaa
     7681 tatgaagatt accaataatt gcccaaccaa tattttcaat tactccgcct gttgtgacaa
     7741 gcggcgtcca atcaggattg atcaagggaa ttgatttccc tatactgatc atcaacccag
     7801 ctgccggcat aactgctacc acaaccatta aagcctttcc aaatttttgc caaaactcaa
     7861 aactaaatat ctttttcatt ccgtttagct cctttacgca atcggtttcg ttaaacgtat
     7921 tatagcgtgc gttttctttt ttgtaaatgc tttatttttt atttttctgt ctataccatt
     7981 ctagaaaacc tataatgcgt gtgttccctt ctataatttt ctcctaaaaa tttatttttt
     8041 tatgcttttt tctatgaaat attttctttt gtctattgac ttgtgcaatc ggttgcgttt
     8101 attatgaacg tataaaacag ctcattagga ggagaaaaat gaaacagatc aaacgactat
     8161 ttgctattga tccatggaaa atcagcacga cacaattaga taaaaaaaat cttcgactgc
     8221 aagaatcttt aacaagtatt ggaaacggtt atatggggat gcgcgggaac tttgaagaaa
     8281 cttactcagg ggaccaccat caaggtactt atttggcggg tgtctggtat cccgataaga
     8341 cacgtgtcgg ctggtggaaa aatggttatc cagaatactt tggaaaagtg atcaacgcct
     8401 tgaactttat cgcgatagat atttcgatca acgatcagct gatcgacttg gcttctttgg
     8461 aaccagaaga cttttactgg gaattagata tgaaaaatgg tgtattatct cgtacattca
     8521 caatcactac ttctactaat aaagtacgca tttccttcga acgttttctg agcattgtca
     8581 aaaaagaatc agcttatatc tatttaacta tagaaatgct tgaaggtagc ggaacagtca
     8641 aactcgtatc aaaattggat ggaaatgttc aaaacgaaga cagcaactat gatgaacatt
     8701 tttggaatga gattgatcgt ggaactatag aagaaatcgg ctatttgacg actaaaacta
     8761 ttccaaacaa ctttgggatt gaacaattta ctgttactgc agcaatgcgc catttcgtta
     8821 atggaaaatc agtcatccct gactatcacg aagatacttt agcattacat ggttgcttgt
     8881 ctgcggaatt atctcaaggt gagacatggt cagtggaaaa agaaattatc gttcttacta
     8941 gtagagatat tccagaagcg cagcaagcag aaaaagctgt ctcagaatta acgaaccaga
     9001 caaacaatta tatccaagca aaagaagagc aaacagcggc ttgggcagaa cgatggaagc
     9061 ttgccgatgt ggtcatcgaa ggagacgaag aagcacaaca aggtattcga ttcaatttgt
     9121 tccaactatt ctctacttac tacggcgaag atgaacgatt gaatatcggc cccaaaggat
     9181 tcacaggaga aaaatacggc ggagccactt actgggatac agaagcgtat gctgtccctc
     9241 tttatcttgc tttagccaaa cctgaagtaa ctaagaatct gctgaaatat cggcataatc
     9301 aactgccgca agcaatccac aacgctcagc aacaaggatt aaaaggcgcg ctttatccta
     9361 tggtcacctt cgctggtgtc gaatgccata acgagtggga aatcacattc gaggagattc
     9421 accgaaatgg cgcgattgcc tatgcaatct acaattatac gaattacacc ggcgatacgg
     9481 aatatttgaa aaatgaagga ctggaagttt tagcagaaat agcacgcttc tgggcagacc
     9541 gtgtccattt ttcaaaacga gcaaataaat acatgatcca cggtgtgacc ggcccaaacg
     9601 aatatgagaa caatatcaat aacaattggt atacaaatac gatcgcagct tgggtcttgc
     9661 gttacacgcg agaaaattat ttaacttatc aaaaagaagc tactatcact atcagcgaag
     9721 aagaactagc caaatggaaa gatatcgcag agaacatgta cttcccagtt gacgaagaat
     9781 taggaatctt tgtccagcat gacacattct tagataaaga tctcatgcct gtatccgata
     9841 ttcccacaag cgatcttcct ctaaatcagc attggtcttg ggacaaaatc cttagatctt
     9901 gcttcatcaa gcaggcagac gtactacagg ggatttattt cttcaatgat acttttacaa
     9961 aagaagaaaa acaaaaaaac tttgatttct atgaaccaat gactgtccat gagtcttccc
    10021 tttcgccaag tatccattcg attttagcag cagaattagg aatggaaagc aaagctgtag
    10081 aaatgtacca gcgaacagct cgcttggatt tggataatta caataacgac acagaagacg
    10141 gcttgcacat cacttccatg actggtagct ggttgtcgat tgtccaagga tttgctcaaa
    10201 tgaaaactgc ccatgatcag ttgagattcg caccatttct gccaaaaact tggaaagctt
    10261 attctttcca tatcaattat cgcggacgtt tattgttcat ctcagtcaca gatgaacaag
    10321 ttactttcga gttattagaa ggttctcctc tagaaattta cgtctatgaa cagtcttatt
    10381 ctttagcgga tcgtctagaa ataacgctaa gaaaggagga agcaaatgtt taaaggggta
    10441 ttgtttgatt tagacggtgt cattaccgat actgctgaat tccattatcg tgcttggcga
    10501 aagcttggtc aggaaatcgg cattacgatc gatcgtacat tcaacgaaca gctaaaaggc
    10561 gtcagccgag aagactcact ctctttgctt ttagctcatg gcggaaaaga acactctttt
    10621 tcaaaggaag aatttgcaga attagcgaaa agaaaaaacg attattattt agagatgatc
    10681 cagacgatcg aaccaaaaga tgtcttcccc ggagtcgtgc ctttactaga ttctttaaaa
    10741 gaagaaaaaa tcaagattgc tcttgcttct gcaagtaaaa acgggccttt cctacttgaa
    10801 aaaatgggtc ttacacctta ctttgatgct attgccgacc cggcagaagc aacaaacgga
    10861 aaacctgcgc cagatatctt cctccttgca gcaaaagctg tcggactaaa agcagaagaa
    10921 tgtatcggga tcgaagacgc gcaagccggt atccaagcca tcctctcaag tggcgctcaa
    10981 ccaattggcg tgggacgtgc tgaagacctt ggagaggaga tcccgcttgt ccctgatacg
    11041 acttttctta cgatcgatta cttgaaagaa aagtggcatg accatggata atccagaaat
    11101 ctccgtcgta ccagttccag agactgaaat aaagaaaatc acattgaaga acgactactt
    11161 agaagtcgtt cttctcaatt acggtgcccg cctgcaccaa atcttcgcac cagacaaaga
    11221 aggaaaatca gaaaatgttt tattgtctta cgatcgtttc gaagatgttc taacagacaa
    11281 aagctttttt ggagcaactg tcggacctgt agccggaagg atccgggatg cttcttgggg
    11341 tgagcataga ttggagaaaa actgcggatc acaccatatc cacggtggca cgaaaggctg
    11401 gtctttccaa ttttgggaag tagaagtttt caaaactcca tcatcaatag gtgtggtctt
    11461 ttacttaaaa gatgaatttt ctacctatcc aggaccaatc actgctacga tcacttaccg
    11521 tttaacaaaa aacgaattag agatgacaac ctctgctagt agccttgttg aaaccatctg
    11581 caatccgacc aaccatgcct acttcaacct ttcaggaaat ggaacaagag acatctatga
    11641 acatcagtta acggtctttt tagatggtgt gcttgaatta gatcaagaaa aactgcctac
    11701 tggaaattgg acaaaaaaag aagaactgcc aatcgacttt agaaaatccc caacactgca
    11761 agagatcctt gcatgttatc cagatggact agatgatgta tttcttttgc atcatcctag
    11821 gctttccaaa acttccttac aattattcga gaagcattct ggtcgcaaaa tgactatagc
    11881 aacttctaat aaaagtatgg tattattttc tacgactgga ttcgaagctg atttctctgt
    11941 caatggaaaa cagatgcatt caaactacgg attagcaatc gaaccgcaag aaatccctga
    12001 tatcgttcat ttccccaaat ttggatcgat caacctccat cctggtcaag aacggatcag
    12061 tcagacgatt tatcggttct ctgcacaata acaagagaaa ggtgttttta tcatggctat
    12121 taccgtaaaa gatgtggcga aaaaagccgg tgttgccacc tcgaccgtct ctcgtgtcat
    12181 caacgatcat cctagtattt ccgagacaac aaagaagaaa gtccgaaaaa ttatggatga
    12241 actaggttat gttcctaaca tgactgcccg caatctagga aaacgcattt ccagtgccat
    12301 cggcgtaatc ttaccccctc ttgattcaaa agagcggatc ggtaacccat tttatcttga
    12361 gatcatggaa gcaatcaacg aagaagcgcg gaattatgat atgactacag caatcgctac
    12421 tgctaaaaat tttgaattgc tgttagagaa cgtccagcgt atgcatttac aaaaacaagt
    12481 agatggtttt attctagtgt attcagatag tcaagatcct gtcattgatt atttatacca
    12541 aaaccacatc cctttcactt tgatcggaca gccttatcat catgagaacg aaatcgttta
    12601 tgtagataat gataaccagc ttctaggtaa acaagcaaca gaatttttga tccagaatgg
    12661 acataagaat atcctgtttg tgacaaacac gactcatgaa agtttgtatt tcgaacgata
    12721 tttcggttat caaaaagcaa tgatgatggc tggtcttcct gcgttatcca gtgtagtact
    12781 agagcatccg gaagattatc tgtcctttga gaaaacgttg aaagaaaacg aagccacagc
    12841 attggtggtc attgacgata tcttcgccct tcgcacgatg cagttggcgc aaatgtacgg
    12901 ctatgtcatt ccagagacac tctccgtcat tagcttcaac aactcgatct tctcaacatt
    12961 aacacaccct taccttacaa gtatcgatat cgatatctcc gaattaggac gtgtcgctat
    13021 gcaaaagctg cgcgaattga tccatgaaga attgagcagt ggcgtacgtt tggtcatccc
    13081 tcatcgcttg atcaaaagag agacagtcgt tcctttagaa aacccatact aaatagctga
    13141 ctcactaaat acgctgacca tttatcctat ggtcagcttt ttatgtaaaa gaagatacta
    13201 cttctaacac attgtttatc tgtaaaaaag agcgtgggac aaaagtaaag aacacttttg
    13261 tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttcg gaaataagct
    13321 gaaattcaca aaaatttaaa aagcaatttt cttgagtttc ttcttatttc ttggagttaa
    13381 acgcttctgt cccagcctct tttttccttc cttcaatttt ttacacgtcg acgattcaat
    13441 aaaaaaccgc ctaatattgt aaagacaggt gcaagaatcg agaaaaaggc gaatggcaag
    13501 taatgcaacg cgctaacttt catcgttccc ataatgaatg tgccgctgac tccccacggt
    13561 acgagagaat tgacggtcgc acctgaatcc gctagtgttc gtgtcaaata ggtttttgat
    13621 aagccaacgt catcaaaaga acgcttgaat gtttctcctg gaagaatgat ggacagatac
    13681 tgttctccaa cgatcagatt gattccgata cagctcaagg cagtaaaccc gactaaacga
    13741 gaaggtcggt ccatcttttc ttttaattct tgaacgatgg tatcaacgat cagatatttg
    13801 atcagtaacc cacctaatgc caatgcaagt aaaatcaaac tagcagaacc taacatactc
    13861 atgatcccgc ctcgagaaag cagttcatct agctttggat caggtgtatt tgcgacataa
    13921 ccattcatca agatgtctgc tgcttttccg accgtcaaac ttttctcatg gataaaagaa
    13981 agaacgagag cagctgtcga tcccgctagt aatgtaggga tagccggaat ctttttgatt
    14041 gcccccccaa ataaaataac tagtggaatc aatgtccaag gagagatcca aaagctcgct
    14101 ttcatgtttt ggatcatttc attgatacta gctagatcgg ctgaatgact gttatgtcct
    14161 aatatcgtat aaaaaatcaa cgaaaggacg aatgctggga aatccgtata acgcatacca
    14221 gcgatatgtt cgaatagatt aactcctcca atacccgctg ccaagttggt cgtatctgat
    14281 aaaggcgagc agttattccc taaaaaggca ccggaaacga ctgcgcctgt agtcattgca
    14341 tcattgaatc caagtaaatg accgatcccc aaaaaagcaa ttccaatcgt cgaaatcgtt
    14401 gtaaatgaac tgccgacagt cactccgaca attgcacaaa caagaaatgc tgtcggtaaa
    14461 aagaaacgca cagaaacaag tttaaatcca taaaccataa tcgtagggat ggttccagat
    14521 aaaatccatg aagcaactaa gacaccaatc aaaagaaaaa tcaggattgg aatgatccct
    14581 ggagtgattc ctttgatgat tccgtcatgg atctcatccc atgtgaactt tttaaatctg
    14641 ccataaaaca acaaacacat gaaagctgca aggatcggga tatgtggcga gagctggaat
    14701 ccgatgatca gtactcctag gagtgccaac aacacgatca atacagcgat actttctttt
    14761 aaagaaatat ttttattcat cgtcgatctc ctatttcaaa tgaaaaggcc ctgccatgaa
    14821 aaaactattc acttggcagg acctcctact aaatcagcga caaaacgtcg gctgaaagac
    14881 ttattttttt atttttcttc taaacttttt tctacctcaa tcccccaaga atctttcttg
    14941 aagtgattga tgatcaatgg aataacgaac atgaccactg tgatagctgc tactaataat
    15001 gcatcactca atgtcgctgt acctaatgta gcaaatacga caacgatgat agagaagatc
    15061 agcatgcagc tgactaccca agctaatccg tttccgtttt taccaattcg gtaaggacgt
    15121 tcgaattctg gatgtttctt acgcatttta agcaatgaaa cagcaatcaa aatgtacacg
    15181 atacaataaa taacagttgt agcatttgta agtgtcaaga atacagcact tacgtcatcc
    15241 attacaccat aaagcaaagc aaataatgaa ataacgattg attgtgttag aacgacattt
    15301 ctagatacgc cgtatttgtt ttctttatgg aatccgaatt ttggtggaag gaatccttca
    15361 cgagctactt ggatgattgt ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc
    15421 acaccaataa ataccatgaa gctgaagata tttccgatca cttctggtaa gcctaggatt
    15481 tgacagtcaa tcaagatagg ctgcgtgata tttgctaatt ccatttttcc atctggtacg
    15541 acatttgcta caagcatcgc attgatgaca ttcaataaaa ctaatccgat caaagcgata
    15601 aatacgcctt ttgtataatt ttttgttgcg tctttcaaac gaggcatgta aacagaactc
    15661 atttcgatcc caacaaaaat aaatgtgata ccagctaagt atttcaatga atcaatatgt
    15721 tccaagtcag ggaaagcttt tgaccatgaa aagtcaccta gatagccgtt tgagactagt
    15781 ccgactttga aggctgccaa aacacctaaa acgaacatga tgactactgg gatatatacc
    15841 cctagccata caccgatgtt cccgccgact tttgccatat cgaatttcaa gttcaagatc
    15901 gtgatgatcc agtagataac taaaatacaa cctaaaacga accagtgatt attgccaagt
    15961 tctacattac caaatgtgtt tcctaacaat ggtcctaaag tagaagcgac cattaccata
    16021 cctgggaaca tttgcaccca taatagccat gcaacgacaa atccccattt gctgcccagt
    16081 gctgttttta cccataactg aggaccgcct tcttgaggaa gcatcgttga aagctcaccg
    16141 gaaaccattg atatcggacc ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat
    16201 gtccaaccga ctgcggctaa cgtaggaata ctccgaaccg ttgcacacag tgccattgtc
    16261 agaccgataa aggtcccaag acccatttta cttacttcag atttactcac cgttgacact
    16321 ctccttgatt ttttggataa aataacgatg tctttgaagt agtttcagca ataaacgaaa
    16381 caattcagcg aatatttgag gggattcttt gagtctattg cttgaagggt ttcttcaaag
    16441 acaacctcaa aacaaaggga tcgaagagct taggtctccc cttgctcttc agatccaaac
    16501 atgcgtcaga aacagttagt attcaagctg ttttctaaca tgattacctt gcttattttg
    16561 cttcgcttgc caataattgg tctgcgtaga ttttttccaa tttttcttga agagctgctt
    16621 tgattttttc agcatattct tcaaagtgtt cttctttgtt catgtatggt gtcattacgc
    16681 tggcacgcaa tacagttact tttccggcac ggttccattc ttcatctgtg aatcctagtt
    16741 ggttcacaaa ttgtaatggg ctgttgccat agtctgggat agcaaagtca gtatgtgaag
    16801 ttaagaactc attaccgtaa atgcttcctt tcacgtatga agaataatca tatacgtcat
    16861 ggttcaattt attcattgca actaagtcat cgttgccttt ttctttgaat acgtagtcta
    16921 ccatattgaa atctggataa gttaatggat gaacttcgat ttctttgtct cctactttaa
    16981 atgacaagtc attcaagaag ttgtagaaac gatgtgcacc ttcgattgat gcacccatta
    17041 atttaccata tcctgtgaca ttcaaaggta agacatggtg tgctgcccaa acgctggctg
    17101 ctgttgcccc tgcttttgaa ccttccaaga tataagcccc aagtaatgct gggatatctg
    17161 cgcctttttc aaatacatat gtcgcaaagt aagagataac gtctctcatg cggatatctt
    17221 tgatgacgat accaccggca gaatatggaa catagcccat tttatgtggg tcaatcgtta
    17281 cagattctgc ttcttcgatt gctttatatg cactgtgtac ttcttctaag atataatctt
    17341 tgttttctgt aaagacattg tatttgtaat gaacatcttt taaatcttca aatggaatga
    17401 agttgttgtc ttcgtctaag aaaatcgcac ggccgtatcc gccataagca gcatctacgt
    17461 gtaagtagaa gtaaataccg tctttttcta atacgcgacg caatgcaacg attttatcga
    17521 taccgtcgat tgctccttct tctgttgatc ctacaacacc gactacacct aggattggtg
    17581 ttttttcagc tgctagacca cgaacgattt tttcaagttc gttgatgtcc atgcgatagt
    17641 tgtggtcaac tggcactgga atcacttggt ctaaaccgat accgatgatg tcggcagctt
    17701 ttagccatga atagtgttta gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt
    17761 ttccgctacg tgctgagtga gctttgattt cgtcgatttt ttctgggacg ctgtctaaca
    17821 gattcatgat ttcttctgtt gacaagttca ttaattccca atcgcttttt ccagcaacta
    17881 gttcaggtgt cacttctttc attgcaagcg gcaatgattt gatgttgcgg gcataccaaa
    17941 gtccttctaa gtttgctaaa gaaccatcag caacgatgtg gccccagcca tctttatagc
    18001 tcattaattt tgcaaattcc attcctactt cttcttccat ttggcttgtt gcaggagaag
    18061 attcataggc aacgttatta ccattccata gcatagcaaa attgtacgct agtaaagatg
    18121 gcatcaatgt ttcagagttc atatgacccc agtaacgtcc ggcattatgc caaggaacgg
    18181 aatgggtacg catccgcgct gaaatttctg atagaacatc ctttgtttta ttcacagtgt
    18241 gttcaaaact agcactgctt ttttcttctg gcgtaataat aggcatgtct tgaggcatgt
    18301 agttttgacg ccagcctaaa tgttcatcca ccaattcatt caacaaagct ttatagattt
    18361 ggccgttctc agctttgtcc ccaatgaata gggcatttag gtttagatct ttcgacaatg
    18421 attcactcat agtgaaaccc tcctaaaaaa atatttaaat tttgtcgagc cctacattac
    18481 acctgttctt ctattctgta aactaagttt tggcctgatt tttaatcata ttttaatatg
    18541 tatcaattat ccgaattgtt cacacttttg aaataattaa aaaaaacgag ggaatttaca
    18601 aatgtaaact ccctcgcaaa gattgtatta acgacaacca gcgttctatt ttaggatggg
    18661 tttcaaaatt ggaatgttgt aatagtattt ccctttttca aggtaaaaac ttactaaatt
    18721 ctaatcaatt actttggcca aaaagtaatt tttcttacct tttcgaataa ccacaaactt
    18781 accatcgaat tcatcggatg gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt
    18841 aatacttata gctccgtttg aaacatcttc acgtgcttga cgtttagatg gttcaatttt
    18901 tgtggaaaca agcagttcca cgatattttc aggtgtgctt gaaatttcaa cgttcggcat
    18961 tttaccgaat ccttgcgcga tttcttccgc atttagttct ttaatatttc cagagaacaa
    19021 tgcttgcgtt attttttgcg cttctttcaa gtcttcttca ctatgcacaa atcttgtaac
    19081 ttcttctgcc aaacggcgtt gtgcttcacg tttctcaggt tctgtctcta cttttttcgc
    19141 taagtcttcg atttcttctt gagacaagaa agtaaagaat ttcaagtatt tcactacatc
    19201 gcgatcatct tgattcaacc agaattggta gaactcaaat ggtgaagttt tcttcggatc
    19261 aagccaaacg gcaccgcctg cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa
    19321 tgggatcgtt aaaccgaacg cttctacttc tggtccttct aattttcgga ttaggtctaa
    19381 tccagctgtg atatttcccc attggtctgc tccaccgatt tgcaattgca catcgtatgt
    19441 tttatgcaga tgcaaaaagt cgatagattg cagaatttgg taagtaaact ctgtaaatga
    19501 gattcctact tccaaacggc tggcaacgat atcttttgct aacatcgtgt tgatgttgaa
    19561 gtttttaccg tagtctctca aaaattcaag taaagagatt tttgacaacc agtcgtagtt
    19621 gttcacaaat gtgatatttg catctttacc aaacaatttt ctcatttgat tggaaagtgc
    19681 gtccacgtta tgttgcactt gttccatcgt ttgcaacaca cgttctgttt tgcggccgct
    19741 tgggtcgccg atcgttcctg ttccgccgcc aatcagaata tatggatgat ggcctgccaa
    19801 ttggaatctt ttcatcatca taaatggaat caaatgtccg atatgcatcg aatcaccagt
    19861 tggatcaacg ccgcaataaa gtgaaatgct cttttcttca acgagctcgc gaagtctttc
    19921 ttcgtttgtt tgctgattaa tggcgtcgcg ccaagttaat tcatcaataa tattcatttt
    19981 actgacctcc gtgtagtttt tttatgaaag caggaacctg ctagcatgtg taattaatta
    20041 tttcttcagg ataggatagg aaataaaaaa agtcccttgg catataagcc aagggacgaa
    20101 atctcgcggt accacccaat ttgtatgtct agatatccaa catacctctc gaacatttaa
    20161 cgctgtcgcg tggcaatcac tgccaaagac tcctgaaatg taattcgctt taaagcatgt
    20221 actggtttgc agcgaccacc agctttctga aacattggct ttaacaacta cttcgtttcg
    20281 atcttcgtct tgttattatt aatatgtgtc tatcatagag cgcaactttt tctttgtcaa
    20341 cagaaaaagg atattttttt taaattcctc attttttctt ttttgaatcc gctctaattc
    20401 cgaacatttt attttcaatt attgttaaaa gaaataactt tttctgtatt ttttctgcaa
    20461 tttatcgaga agtcacttta ctttgcctct tattctttct tcgttacaat aaggaatggg
    20521 acaagtaaaa aaatgaaaaa gcaagggacg aggtatatgg aaaaaaagca aaaaattatt
    20581 ttaggagcca cttctgcttt aactatcgtt attttaattc taagtttgtt ttttgtcatc
    20641 cgatcatcta caaaaaaaga accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa
    20701 gaaccgacag atgataagca acaactagtt actcaagcaa aaaatctggc tcaaagctac
    20761 gattatgacc aagcgattgc gttattggaa aaagatagta agaacggatc tactgaaaca
    20821 caacagcttc ttcaaacact aaaaaaggag aaagaacaac tgatcgactg gtctgatcct
    20881 actcagatct ctcatgtctt tttccacagc ttgatcgtgg acccgcaaaa agccttccac
    20941 tctcaacagg cacaaggata caaagattat atggtgactg ttgaagaatt caaccgttcg
    21001 atcgaacaac tttatcaaaa tgattttgtt ttagttaatt taaatgattt gatccaaaaa
    21061 gacgaacaag gaaatctttc ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg
    21121 gttctttcac aagatgatgt cagctattat gaatatatgg ataattccgg ttttcctagc
    21181 cgattggtcg tatcaaataa caatgaaatc aaaaatgtct ataaagagaa agataaagaa
    21241 gaaatcggtg actttgacat ggttcctctg atcgatgcct ttgtcaagaa acatcctgat
    21301 ttttcttatc gaggcgcaaa aggtaccttg gccctgacag gttacaacgg agttttaggt
    21361 tatcgaacat caaaatctca atatggagac aatgaaaaaa caaaaaaaga gattaaagaa
    21421 gctaaaaaag tggcggaaca gttgaagaaa gacggctgga gctttgcttc ccatacatgg
    21481 ggtcacttga atatgactca agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg
    21541 cagcaagaag ttgcacctat cctaggaaaa acaaatattc tgatttatcc atttggtgca
    21601 gacatcagcg actggcagcc ttattcagca gaaaatcaaa aatttgctta cttgaagagt
    21661 caaggtttcg atattttctg taatgtcgat gcttctacac cagcttgggg acaattaggt
    21721 acggatttct atcgaaatgc tcggatcaat atcgatggca ttcgttttca atctgattta
    21781 gacggaaaaa atcctattct tgatccattc atcaatgtcc atgatgtcta tgacaaagaa
    21841 gcacgcgaat ctgcttgatt ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt
    21901 atcgtcagtt tcggcttttt tatgctttat ttcttcttcg gtgcgattcc cttgatcagg
    21961 acttctgtcc attctgctgt atatggaagc agttttgcgt atatctccgg cttagaaatt
    22021 ccttctacca ttgcttgaaa atagaggatc aagaactcat ccgaatattt caaatccact
    22081 tttccttctt tccgccctcg atggaaaaga tcaagcatga tactgaaact ttcttgcgta
    22141 tacgcatcca tcgcgtcaga aaattctttt ttttcttttt ttgtatagta tgtcatcaaa
    22201 tcgatataaa attgtttgtt cactcgattg agataacgga ttttgttttc actcatggca
    22261 atcagtgttt cttcaaatgg aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa
    22321 tcattcataa atgcaaaaaa tacttcataa atcagccctt ccttgctgcc aaaatattta
    22381 aaaatcgtcg ctttacttac ctgagcgttc tcagctacct tatccattgt cactccagcg
    22441 gttcctatgt ctgtgttcat caagtcaaaa gctgcttgta aaatctcttt ctttttctct
    22501 tgtgctctct tttcaaaacc gttcatttgt agagcctccc gtaattttaa acttttataa
    22561 tatatatagt tcaaatttat tctgaggttt attataacta tctattgaga aagtatcaag
    22621 ctagcaattc cttgtttatg aattcattga cagaaattta taaaaagaat attatgtact
    22681 aaaataataa aa
//
LOCUS       DAXLPY010000042        22651 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.042, whole genome shotgun sequence.
ACCESSION   DAXLPY010000042 DAXLPY010000000
VERSION     DAXLPY010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.042"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            178..696
                     /locus_tag="ACF3UF_001736"
     CDS             178..696
                     /locus_tag="ACF3UF_001736"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD3671847.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            824..1507
                     /locus_tag="ACF3UF_001737"
     CDS             824..1507
                     /locus_tag="ACF3UF_001737"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFD3671848.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1816..1889
                     /locus_tag="ACF3UF_001738"
     tRNA            1816..1889
                     /locus_tag="ACF3UF_001738"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1850..1852,aa:Arg,seq:tct)
     gene            2048..2407
                     /locus_tag="ACF3UF_001739"
     CDS             2048..2407
                     /locus_tag="ACF3UF_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFD3671849.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2530..4161
                     /locus_tag="ACF3UF_001740"
     CDS             2530..4161
                     /locus_tag="ACF3UF_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFD3671850.1"
                     /translation="MFKKYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4223..4864)
                     /locus_tag="ACF3UF_001741"
     CDS             complement(4223..4864)
                     /locus_tag="ACF3UF_001741"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFD3671851.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5050..5126
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5146..5454
                     /gene="rplU"
                     /locus_tag="ACF3UF_001742"
     CDS             5146..5454
                     /gene="rplU"
                     /locus_tag="ACF3UF_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFD3671852.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5481..5825
                     /locus_tag="ACF3UF_001743"
     CDS             5481..5825
                     /locus_tag="ACF3UF_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFD3671853.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5838..6131
                     /gene="rpmA"
                     /locus_tag="ACF3UF_001744"
     CDS             5838..6131
                     /gene="rpmA"
                     /locus_tag="ACF3UF_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFD3671854.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6565..9372
                     /locus_tag="ACF3UF_001745"
     CDS             6565..9372
                     /locus_tag="ACF3UF_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3671855.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9563..10054
                     /locus_tag="ACF3UF_001746"
     CDS             9563..10054
                     /locus_tag="ACF3UF_001746"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFD3671856.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10157..11146
                     /locus_tag="ACF3UF_001747"
     CDS             10157..11146
                     /locus_tag="ACF3UF_001747"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFD3671857.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11179..11982
                     /locus_tag="ACF3UF_001748"
     CDS             11179..11982
                     /locus_tag="ACF3UF_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFD3671858.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            12003..12917
                     /locus_tag="ACF3UF_001749"
     CDS             12003..12917
                     /locus_tag="ACF3UF_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3671859.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            13000..13374
                     /locus_tag="ACF3UF_001750"
     CDS             13000..13374
                     /locus_tag="ACF3UF_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFD3671860.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13513..13758
                     /locus_tag="ACF3UF_001751"
     CDS             13513..13758
                     /locus_tag="ACF3UF_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3671861.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13930..14994
                     /locus_tag="ACF3UF_001752"
     CDS             13930..14994
                     /locus_tag="ACF3UF_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFD3671862.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15240..15665
                     /locus_tag="ACF3UF_001753"
     CDS             15240..15665
                     /locus_tag="ACF3UF_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3671863.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15658..16107
                     /gene="nusB"
                     /locus_tag="ACF3UF_001754"
     CDS             15658..16107
                     /gene="nusB"
                     /locus_tag="ACF3UF_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFD3671864.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16204..17058
                     /locus_tag="ACF3UF_001755"
     CDS             16204..17058
                     /locus_tag="ACF3UF_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFD3671865.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17059..18396
                     /gene="xseA"
                     /locus_tag="ACF3UF_001756"
     CDS             17059..18396
                     /gene="xseA"
                     /locus_tag="ACF3UF_001756"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFD3671866.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18401..18625
                     /locus_tag="ACF3UF_001757"
     CDS             18401..18625
                     /locus_tag="ACF3UF_001757"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFD3671867.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18627..19517
                     /locus_tag="ACF3UF_001758"
     CDS             18627..19517
                     /locus_tag="ACF3UF_001758"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFD3671868.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19526..20344
                     /locus_tag="ACF3UF_001759"
     CDS             19526..20344
                     /locus_tag="ACF3UF_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFD3671869.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20451..20900
                     /locus_tag="ACF3UF_001760"
     CDS             20451..20900
                     /locus_tag="ACF3UF_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD3671870.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20918..22600
                     /gene="recN"
                     /locus_tag="ACF3UF_001761"
     CDS             20918..22600
                     /gene="recN"
                     /locus_tag="ACF3UF_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFD3671871.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
BASE COUNT         7391 a         3753 c         5014 g         6493 t
ORIGIN      
        1 gtaaacgttt tttaaactaa cgtcaattat ttataataaa aaatgagata aagatgagga
       61 aatagaatta gaaacatata attattaaag ggaaacattt ttacagctat aatttgaaaa
      121 aaatttatcg ttattatatg attaagaagg attgaataaa gaaagaagtt gaaaacgata
      181 cctgattaca aaaaaataac ttttataagt tctataacgt tgattatatt tttaattctt
      241 attcttctcg tcgtcttggt tccccgaatt tttggtttga ctccttatat tattgaggac
      301 aaagaaatga gtccatatta tgcacaagga aatctgatat atgtacgacc gaaaaataca
      361 aatgagattt tagtcggaga tattattaca tattatgaaa attcaggaaa aaaaatctcg
      421 acgcgtcgcg taatagccgt tgaaaacaac cacgaagatt tttatacaaa agctgataca
      481 aagacttata ttgagcctgg agtagtaaaa aagagaaata ttatcggtag tcccatcttt
      541 cagattccat atattggact agtcctttca aaaacggcat ttgcatggat tcaggggtta
      601 ttctttacga ttgctttttg cctaacagga atcacagcat ggaatacctt tgtagagttg
      661 aaaaagaagc ggagacgaac acagaaattt ttgtaagaat gttaaaaaca taaatgtatt
      721 ccagagatcc aacgactctt ctgaacatga aacacgagaa aacactcatg cagcttgtag
      781 atttagtcag ttgttcgtat aatgtgtgaa gaggaggagt agtatgcgca atgaaatgat
      841 gcatcgtcct gtagtcaaag aagaactatt ggattttatg cgtacccagc aaaaaaaatt
      901 accgggtgag ctaggcaaac tggaagaaga agctcatgta gcagaagtac cagttattcc
      961 ccatgaaaca gttgtatttt tgaaattttt acttggacag cttcagcctg aacgaatctt
     1021 ggagatcgga gcagctatcg gtttttcatc aagtgtcatg gccacgacaa tcggagaaaa
     1081 cgctcatgtt acgacaattg atcgtttcga tgtcatgatc gagaaagcta aaaaaaacta
     1141 tgaacgtcta ggactgacag ataaagtgac tttgcttgaa ggtcaagcag cagatatctt
     1201 gccggagttg tctggtccgt atgactttat ttttatggat agtgcaaaat caaaatatat
     1261 tgaattttta cctgaatgct tacgtttgtt aagaaaaggt ggcgttttga tggtagatga
     1321 catcttccaa ggaggaacga tcttgctccc agatgaagag attccccgtg gcaaacgagc
     1381 tatccatcgt aaattaaatg aatttcttcg tgttgtgatg gatcatcccg atttgacatc
     1441 gacaatcttg ccattaggtg atggtgtgat cttaatgaca aaggaatcag aaacaatcga
     1501 gttgtgatac atgattatgg cagcctgtag ataatcgatt gaatcgaggg ctcaattcga
     1561 acttgatgta aaagtttcta tatttgtaag tcaattaaag gatacaggaa atctaaataa
     1621 acaggagtag catgaagtca atgtagctcc tgttttcaat tgataacctt agaacagctg
     1681 aaggagaatg tctcgtttta aaagattgat ttagtagttg ggccaaaata attcattatt
     1741 tgctaattaa ataactattt cgtattgaca gaagcaattt aattatctat aattattgat
     1801 gttccgctga ttcttgtcat agtagctcag ctggatagag catccgcctt ctaagcggac
     1861 ggtcgggggt tcgaatccct cctgtgacgc taaaaaaccg ttagaaactg aggtttctaa
     1921 cggtttttct ttgttttttg tgccaatatt gtttgttttc aaaggcaaat aaaataaaaa
     1981 aacatcctta tcgagtacaa ttataaggag caaaaaaata aaactcatca gaaaagagga
     2041 agaagatatg acgatactat ctagaatttt agtgactcta gttgcaattg aattttttta
     2101 tatcatgtat atcgaaacgg tgagaactga ttctgacacg acaagtaggg tttttaaaat
     2161 gagtaaagaa gagttaagca gaaaatctgt tcaaacattg tttaagaacc aaggagtgta
     2221 caatggacta ttaggagtgg gactacttta tggagcttat ctttcttccg catctaaaga
     2281 aatcacaagt atgctattaa tatctatttt ttttgttgca ttatatggca gtttgactag
     2341 cgatcgttgg attttactca aacaaggtgg gctagctctg ttggcattgc tttctatttt
     2401 cttataaata tagaaaaaat aagaatttat ctaacaggaa actttgtgaa aaatattact
     2461 ttatctcatg aaatatgata ttctaatgaa tggtatttta gaaaatttca tgaaaaagga
     2521 gttagatagg tgttcaaaaa atatgtttcc tcactaaaaa aagaattttc aggttatgat
     2581 ctttcaagat ttcagaaaga tcttttggct gggatcacag tagctgctgt agcattgcct
     2641 ttagccttgg cttttggggt atcaagcgga gctgatgcgg ccgcaggttt gattacggct
     2701 atcattgccg gtatcgttat tggcggttta tcaggcggtt tttatcaaat atcaggtccg
     2761 acaggtgcga tggcagctat cttgatgtct attgcggcaa caaagggaat gcaaggtgta
     2821 ttgcttgcta cttttttagc gggtctattt ttacttgcag caggactttt ccgattagga
     2881 acactgactt cttttatccc agcacccgta attacggggt ttacttcagg tattgctatc
     2941 attattgcat taggtcagat cgataattta tttggtgttc actcggaagg tacaaacgtt
     3001 attgaaaaac taagtagtta tcaaacgata ggatttccga taaacacagc ctctttgatc
     3061 atgggagggc tagtcatttt agggatgttt atctatccaa aaaaatgggc gaaacgaatg
     3121 cctagttcgc tgctggctat cattttggca acagcagtta tgctattgtt ccatttacca
     3181 gtagcaactg tgggtaagat tccacaaaca ttgatcagta gtaatcgttt gaatatggga
     3241 gattttagct tttctgcctt gcaacaagtg gcagttccag ctattagcat tgctttatta
     3301 ggaatgattg aaagcttgct atgtggtgct tcggctggcc gaatggcaaa taagccctta
     3361 gatagcaatc aagaattaat ggcgcaagga attggaaatc tgttgcttcc tttctttggc
     3421 gggattcctg ctactgcggc catcgcccgt acaagcgtgg ccatcaaatc tggtgcacaa
     3481 actagattag ctggtatgat acatgcagtt gtcttactgc tctccatgct tgtttttgcg
     3541 ccagtgatgt cacagattcc aatgccagca cttgcaggtg ttttgattgt gacggcttgg
     3601 cgtatgaatg aatgggaaac gatcaaggag ctatttacta ataaatattg gtcagcagtt
     3661 ctattgttta tccttacgat gatttgtaca gttatctttg atttaagtat tgctatcgtg
     3721 atcggggtga tcggcggctg tgtatttttt gttgtcaaaa gcgctgctat cacgatttca
     3781 ttagaaacga tcgattggca aagaatgggg ctgccagaaa cggaaaagct gaataactgg
     3841 acagtagtgt atattagtgg tccactgttt tttatgtctt cagaaaaact caaaaataaa
     3901 ttggaagaac taaatcatca cgatggtgtc attttctcca tgcgaggcgt accaagtatt
     3961 gatttgacgg cacgtgcagt ttttgatgaa tttcaagaaa aagcagagca aagaggacaa
     4021 acgattatct atacttcctt gcagccagaa gtagaaaaac aactttctca cttgtgggaa
     4081 catacattca cgcatcaaca tcaaacagtt gctcatgcgt tgacagcttt acatgcgaaa
     4141 tatactgcaa ttagccatta aaacaatgaa aaagaacaga caagactgta aactgaagat
     4201 tttatggtct tgtctgttct ttttaatatt gctgtaaaag tgaagctagt acttgccagt
     4261 cttgatggat aacaggtaca agggagcgat tgtagaaaat agctgctgga tgaaaaagtg
     4321 gaagaattcg atagtttttt tctgaccatt cgtaggcatc cttttgttct gttaattgta
     4381 agacaggccc tgtatagagt tgaccatgat ttttggtaac cgtatattct ttgccaagta
     4441 aacgttgaag accaatgttt ccaagtgtcg caattaattt tggctggacc ttcatcagtt
     4501 cgtaatccaa tattggtgca tgcgcaaata cttcggaacg agtaggtgtc cgatttggat
     4561 aaacagtttc tgactgttgt gtccgtttat tgatccgatg agtcacgcga tacgggcggc
     4621 tccttacagc actggtgata tacacctctt ctcgtgttaa gccagttgaa gaaagtgcct
     4681 gcatcaattc ttttccagct tgaccgctaa aaggaacatg cgtatcaatc tctgttttcc
     4741 ctggggcttc tcccacgagc atcagtttag gatgaagagg tccttgccca gcgataaatc
     4801 cttctacagg acggccgttc attcttaaag aagcttcttg tatcagttct tttgggtatt
     4861 ccatttatgc tcctcctttt tcttttatta taagaataaa agaaacacaa tgcgactatt
     4921 ttatttggta gaactgtgag gatagaaaag cagaagtatt gcttgaattt ttgttttact
     4981 ttttgatttt aaatttagtt gactaacggt tgctgttctg gtaagctagt actgttgtaa
     5041 ttgtggactc cacagctaca accgctcaga acaagtaata agcacagcat atgctgtcac
     5101 ttcggatggc gagtctaagt atatgagaag gaggtgcttt atagcatgta cgcaattatt
     5161 aaaactggtg gtaaacaagt aaaagttgaa gtgggacaag caatctatgt tgaaaaactt
     5221 gacgttgaag caggagaaaa agttgttttt gacgaagtta tcttagtagg cggagaatct
     5281 acaaaagtag gcgctccaac tgttgcaggt gcaactgttg aaggtactgt tgaaaaacac
     5341 ggcaaacaaa agaaagtcgt tactttcaaa tacaaaccta aaaaacattc acaccgtaaa
     5401 caaggtcatc gtcaaccata tacaaaagtg gttatcgacg cgatcaacgc ttaatagcgt
     5461 ttgagaaaga aggcctatat atgatcaaag gaacatttaa gcgaaatgac gcaggtcaga
     5521 tcgtttcatt cactttgacc gggcatgctg atgctggtcc ttatggaagt gatatcgttt
     5581 gtgcgggtgt ttctgcgtta gcgatcagca ctgtcaacgg gattgcctca ttagccggtt
     5641 ttgagccgat tgttgaaatg aatgaagaag aaggcggtta tctttatacc gaagtcactt
     5701 caggaatgac acaagaacaa aacaatattg ctgagattct attagaaaat cttttattag
     5761 gattacaatc gatagaagct gaaaactcag aatatatcca aattaaaaca attaatgata
     5821 aataggaggt gcagaccatg ttgttatcta tgaatctaca attatttgcc cacaaaaaag
     5881 gtggcggttc tacatctaac ggccgtgact cagaatcaaa acgtctaggt gctaaacgtg
     5941 ctgatggaca aacagttaca ggtggatcaa ttctttaccg tcaacgcggt acaaaaatct
     6001 atccaggtgt aaacgtgggt atcggtggag acgacacttt atttgcaaaa gttgatggcg
     6061 tagtacgttt cgaacgtaaa ggccgtaaca aaaaacaagt gtctgtttat ccagtagctc
     6121 aagaagctta attgaatctt atgattaaag aggttgtgac aagacttttg tcacagcctt
     6181 ttttgtttat aaaaataaaa gttgtagtgg aggctacgaa gtttactttg tctttttaca
     6241 cttaatattt ttttgccaat ttggaatcag gatgttttga taactatcgt tttcaattga
     6301 tggaagctat attgtttgct atcagtgaaa taattatatg gtaaacagtg ttctttttct
     6361 tgtttccatt ataaaaatcg tatcgggatt tttcgttctt ttaaattgaa catttctatc
     6421 tatccgcgtg ttatcaacaa aacaaaatca ggtaaatagt tgacgaaaca gaaataaata
     6481 catagtatta tgttttgaag cctaagtaca atagtctata gaaaaggagc gataccattg
     6541 gcaaaacgca ttgaccgaat ttatatgtat gtcaaagaaa aaaccgctca tttaacaaag
     6601 gcagaatatg atcaaggagt aacaacacag gaaattgctg aagtgttagg gattcagcga
     6661 acaaatagca gtaaagatct gaatcagcta gtgcgcgaag gaaaactgat aaagacagac
     6721 ggacgaccag tacgttacat atatcaaaca ctcgttacgc acgtaaagcc agttacaaaa
     6781 catgtagtca gttacaaaga aacgccggtc tctgaagaaa aaaatacact ccaaatagat
     6841 actaaggata tctttgcaaa aatcattgga gctaacggca gcatgaaaaa ttcagtggaa
     6901 caggcaaaag ctgcgatttt gtatccgcca agaggattaa attgtttgat tacaggacct
     6961 accggatcag gaaagactta ttttgcacac gcgatgtatc attttgcaaa agcgcatcat
     7021 gtaatagatg aggaaacgga actgattgtt ttcaattgtg ctgattatgc caataaccct
     7081 gagcttttga tgagtcattt atttgggtac gcaaaaggtg cttttacagg cgcagatgaa
     7141 gaaaaaatgg ggattatcga tcaagcggat ggcggtatgc tgtttttgga tgagattcac
     7201 cggttgccgc ctgaaggtca agaaatgatc ttttacttta tggatcatgg aacttacagt
     7261 cgtcttgggg aaacaacgaa atcccatgaa gcaaatgtac ggatcgtagg tgcgaccaca
     7321 gaagacccag gttcttctct attagaaact tttgttcggc gtatcccaat caatatcaaa
     7381 cttccggctt ttgaaaaacg tcctgcaaat gagaaagtcg atttagtaaa aatcatgatt
     7441 gcccacgaag caaaccgcac gcagcgaaag atttctttga cagaagatgt agcaaaagca
     7501 ttgatcggca gtgtgaccta tggaaatata ggacaattga agtcaaatat ccagttagta
     7561 tgtgcacgag gatttctaaa tcatatgcaa tcacccgaaa tctcgatcac aatcgatgat
     7621 ttgacagaag ggattcgtag cggattgatt caattagcaa gcaaccgcag tgcaatggca
     7681 gagctttcta aaatattgga gccaaagata actgtagcac caaatgatac gatcatgaaa
     7741 atccaatcgg actcctatga gttaccttat aatctatatg atatcatcgg agataaagca
     7801 gctttactga agtcggatgg tttggatcaa gaagcaatca atcatttcat ttctacagat
     7861 atcaacatcc atctgaagtc tttctataaa gaccatggtt tttcttttaa tgcagacagc
     7921 aaattagcag aatttgtaga tccgaaaatc atagaagtga ccaatcagat ttatgtaatg
     7981 gtcaaaagat ctttaccata tgagtttcag caaaacttta tttatgctat gagcttgcat
     8041 atcagttctt ttttgaaaaa aatcaactta ggagaagaac ggcatacgaa tgataacatc
     8101 cgtgagatgg cttttgattt tccagatgaa tatgctgttg cgaaagaagt gcgtagttat
     8161 atcgaaacgt attttcaagt ggagattcca gaaagtgaag actattactt gaccgttcta
     8221 ctcgtctcgt tacgggcaaa tcaagcaagc ggcagaatcg gtgtagtcgt tgcagctcac
     8281 ggaaacagca cagcaagcag tatggtccaa gttgtccaac agttgttaga tgcagagaac
     8341 gtacgagcag tagacatgcc tttggatatg gatccgaaaa cagcattgga ccgaattgaa
     8401 cgcaatgtac aagaagtaga tgaaggaagc ggggtcatac tcttagtaga tatggggtcc
     8461 cttgcgtcgt ttaattcgca aattcaaaga gacactggaa ttccagtacg tactgttgat
     8521 atggtaacaa cttctctagt tttggaaact gtacgaaagg tctcagtatt agggacagat
     8581 ctagatatgt tgcatgaatc attgaaaaat tttcgaggtt acgcagaaat atcttctgta
     8641 gaatctgttc aggaagcaaa acctattcat aagaaaaaag ctgttttggc tatctgcgca
     8701 tctggcgaag gtacagcaca aagaatcaaa gaattgatcg aacgagcggt aaacaagcgt
     8761 caagaaacag aattagaagt tctagctttg tcgattgtgg aagtgaaaga agaactgcca
     8821 gttatccaaa aagaatatca gatcatagct actactggga ttactgattt gaatatccaa
     8881 gccccattta ttcctttaga acgttttatt gatcaaaata tcgaagtcat tttggatcag
     8941 ttgctgatgg aatcagaatt ggaggaaact gaattcatct ccctagatga agagtcagct
     9001 aaaaatacgt gtgttgagtt tatctctgat aacttcatct ttattaatgg tagtaagtta
     9061 atcgatccaa tgtggcaatt ttctacacaa atctctcaga cgacgggaat cggcgatgaa
     9121 gaatatggat tcaaaatcaa cctagtgatg cacacagcag gaatgatcga acgtattatt
     9181 cggaatgaac cattgactgt ggaagaaaac gaattgacaa atacaacgaa tgatcctctt
     9241 tatagccaat tggcagcctc agttgttctg ttggaagatc agataaaagt aaaagtgccg
     9301 atagaagaaa tgtattatct gctacgtcta gtccataatc agttagataa aaaagaatac
     9361 actgtgccat gaatacacaa aaacgataca cttttatagt gtatcgtttt tgtgtattgg
     9421 ttaagaatcc tttaaattca attagtgtat cgtaaaaaag ttggcacgct ttttgcttat
     9481 agtagtgtgt gctaggaggt ggttgttcac acagaaatga taggggtttc tgtgaagtag
     9541 tgaggaagaa ggagttttgc agatggatat tcgattggca cgtatagatg atcgtttaat
     9601 ccacgggcaa gtcgcaacag tttggtcgaa gcaaacaggt gttgaacgta tcattgtgat
     9661 cagcgatgta gtcgctcaag ataaattgag aaagtttcta ctaaaagaag ctgcaccgcc
     9721 ggggatcaca gcaaatgtaa taaccgtgca gaaaatgatt caaatctatc atagtggatt
     9781 attatcacga gcaaaagtga tgcttttatt caccaatccc caagatgttg aagcggttgt
     9841 ccgctgcggt gtacagttga agtcgttgaa tatcggcggt atgagtttta ctgaaggcaa
     9901 atcaatgatt accaattttg tttcagtaaa tcaacaagat attgattcct ttcgttactt
     9961 gaacagtcaa gaagtggagt tagagattcg aaaagtacct gctgacagga aaatcctttt
    10021 gatggaacta ctagcgaaaa tcaaaaaggt gtagcaagaa tggttgttgg aaaaggtcaa
    10081 ataattctgt tgtaatggtt agcaattatt aatatttttg aatttgttac aacaaaagta
    10141 aataggaggt ataaatatgg tagggattat cctagcaagt catggacaat ttgctgaagg
    10201 aatcttacaa tccggttcaa tgatctttgg cgaacaagaa aacgtcaaag ccgtgatttt
    10261 gaaaccaagt gaaggtccag atgacttgag agccaaattg gaagaagcgg ttgcttcttt
    10321 tgataatcaa gacgaagtgt tattcttagt tgatttatgg ggcggaacac cgttcaatca
    10381 atcaaacaca ttattcgaag agcacaaaga taaatgggca atcgtcagcg gtttgaattt
    10441 accaatgttg attgaagcct acgcatcacg cttttcaatg gaatctgctc atgaaattgc
    10501 agcacacatc attgaaacag caaaagacgg tgtaaaagta aaaccggaag aattagaacc
    10561 ggcagaagca ccgaaagcag cagttgaaga cgcacaacct aaaggagcac ttccagaagg
    10621 aactgtggtc ggagacggaa aaatcaaata tgtattagca cgtgttgact cacgtctgtt
    10681 acatggacaa gttgcgacag cttggacaaa agcagtgcaa ccaaaccgta ttatcgttgt
    10741 ttcagatgca gtatcaaagg atgatctgcg taagagacta atcgaacaag ctgctcctcc
    10801 aggtgtaaaa gcaaatgtta ttcctattag caaaatgatc gaagtagcaa aagaccctcg
    10861 ttttggaaat accaaagcat tgcttttatt tgaaaatcct gaagacgtat tgacagctgt
    10921 tgaaggtggc gtagacatca aagaattaaa tgttgggtca atggcgcatt cggtcggtaa
    10981 agtcgttgta agtaaagtat tgtctatggg acaagaagac gttgaagcgt ttgagaagct
    11041 tgaacaaaaa ggtgtgaaat tcgatgtacg taaagtacct aatgattcac gcgataacat
    11101 ggatgatatt ttgaaaaaag caaaagctga attagcaaaa gcgtaataaa taatattaaa
    11161 atttatagga ggcttatcat gtctattatt tcaataattt tagtcgtatt agttgccttt
    11221 ctagctggta tggaaggtat tcttgatgaa tttcaatttc atcaaccact agtggcatgt
    11281 acattgatcg gtttagttac cggtaacctc gaagctggta tcgtacttgg cggtacgctt
    11341 cagatgatcg ctttaggttg ggcaaatatc ggtgccgctg tagcaccaga tgctgcatta
    11401 gcatcagtag catcagcaat tattttagtt ttaggtggac aaggtgttaa aggtgttcct
    11461 tctgcgatcg cgattgccgt tcctttggct gttgcagggt tgttcttaac aatgatcgta
    11521 cgtacaatcg ctgttccaat cgttcatttg atggatgcgg ctgctgaaga aggaaacatc
    11581 cgtaaggttg aaatgtggca catcattgct gtatgtttac aaggggttcg tatcgcggtc
    11641 ccagcagcag cgttgctatt tatcccagca caaactgtgc aatcattcct tgaatcaatg
    11701 ccagcatggt taacagatgg tatggctatc ggtgggggaa tggtcgtagc tgtaggttac
    11761 gctttggtaa tcaacatgat ggctacaaaa gaagtatggc cattcttcgt tattggtttc
    11821 gttgtagctg caatttctca attaacattg attgctctag gtgctttagg tgttgcatta
    11881 gctcttattt acttgaacct ttctaaaatg ggtggttcat caaataatgg aggcggaagc
    11941 aactctggtg accctttagg cgacattttg aatgactatt aatcttgaag gaggaaaata
    12001 aaatggcaga agaaaaaatc aaattatcaa aaaaagatcg tttagctgtt gcgtggcgct
    12061 ctaccttcat tcaaggttca tggaactacg aacgtatgca aaacggtggc tgggcatttt
    12121 ctatgattcc agcaatcaaa aaattataca aaacaaaaga agaacgttct gcagcattaa
    12181 aacgtcactt ggaattcttt aatacacacc catacattgc ttctccaatt ttaggggtta
    12241 cattggctct ggaagaagaa cgtgcgaatg gcgcgcctgt tgatgatgta gcgattcaag
    12301 gggttaaagt aggtatgatg ggtcctttag ctggtgttgg tgacccagtg ttctggttta
    12361 cagtacgtcc aatgctaggt gcactaggtg cttcattagc tatgggagga aatatccttg
    12421 gaccaatcat cttcttctta ggttggaaca ttattcgttg ggcattcatg tggtatacac
    12481 aagaatttgg ctacaaagct ggttctaaaa ttactgatga cctttctggc ggattgttac
    12541 aagacgtaac aaaaggtgct tcaattttag ggatgttcgt attagctgcc cttgtacaaa
    12601 gatgggtatc aatcaaattc ttaccagttg tatcaactgt aaaattagat aaaggtgctt
    12661 acatcgaatg ggataaattg ccttcaggtg gtgaaggaat caagagtgca tttgaacaag
    12721 ttaataatgg cttagccctt tctcctgaaa aggtaacaac attacaagac aacttagacc
    12781 aattgattcc tggtttagct gcattaggat taacattgtt atgtatgtgg ttgcttaaga
    12841 aaaaggtttc tccaatcgtt atcatccttg gtttattcgt agtcggtgtt gttggacacg
    12901 tcatcggact tttataatcc ataaaaatat agctcgggcg ttgtcccgag ctttttttat
    12961 atagtatact gttcataaac aaatatctgg agggagaaaa tggttcaatc aatcaataca
    13021 aaagtagact tggtaattga tgctacttcg tttacgggtc tgacagatta cgggcaaatc
    13081 atgataggtg ataatggttt tgagttttac catgcgcgag atagacgcaa atatatccaa
    13141 attccatggg aagaagtgga ttatgtacta gcatcagtca tgctaaaggg aaaatggatt
    13201 cctcgatatg ccattcaaac gaaaaaaaat ggtacataca cattttcttc caaagaacct
    13261 aaaaaagtgc ttcgtgcgat cagagaatat gtagatgaag atagaatggt acaatcattg
    13321 agtttctttg atgtagtgaa acgtggtatt cgtagtatgt ttaaacgcaa gtaaaaaata
    13381 aagaaaactt ctaagaggag gttttcttta tttttttact ttgcagaaga aaatatgaaa
    13441 tagcaaaacc aattatttgt cccctttaaa tcccatatgc taaaattgat tagcaaagaa
    13501 ggaggttata ttatgagttg gttatggaca ttgattgttg gagccgtgat cggagcaatt
    13561 gcaggtgcga tcaccagtaa aggaaattcg atgggctgtg taacgaatat cattgctgga
    13621 ctagtcggtt caagtattgg acaagcgatt ttcggcgaat ggggaccaaa agctgcaggt
    13681 atggcactta ttccatctat tttaggcgca gtgattttgg tagcagttgt ctcatttttc
    13741 tttggaaaac gatcataagt ttttacaaaa tagtaaacta aaaggagttg cagcgagact
    13801 gtgactcctt tttggcttta tttatttaaa ataaaaagaa gttttccgga aatttttatt
    13861 taactgtcgt gtacgaagaa aagtttgcta taatggaaaa aagcgtgcaa agaaagaggg
    13921 agtttcatta tgatgctacg tgtagaaaaa ttgcgcaaaa aaatgcaaga agaaaatttg
    13981 gattcatttt tggttaccag tccgtacaat cttcgttact taacgaactt tacaggtacg
    14041 acaggattag ctgttattac tttggaaaaa gcatttttta ttactgattt tcgttatacc
    14101 gagcaggcgg cagcgcaggc tcaagggttt gaaattatta aaaatgtcgg acctattttt
    14161 gatgaggtag caaacttagt acgcaaagaa gaactgcact cattagcttt tgaggaaaca
    14221 acagtctcat ttttagaata ttcggtttta gaagaaatca tcgatgcgga attagtacct
    14281 gtttcacaga tgatcgaaga actcagagaa gtgaaagatg aagaagaaat cgctattatc
    14341 gaaaaagcat gtcatattgc ggatatggca tatgatcaca tcctgaaaat gatccaaccg
    14401 ggcatgactg agattgaagt cgcaaatcaa ctagactttt atatgcgttc tcttggcgct
    14461 tcaggtgttt cttttgatac gatcgttgct agcggattgc gttcggctat gccgcatggt
    14521 gtagcaagca aaaaaatcat cgaacaaggt gacttgatca cattggactt tggttgctat
    14581 tacgaagggt acgtttccga tatgacacgt acattcgcta ttggtgatcc tggggaaaaa
    14641 ttaaaagaaa tttatcaaat agtcttagat gctcaattag cagttattga tgctgcaaaa
    14701 ccaggaatga ctggtgtcca attagatgca gttgctagag attatatttc aaaacatggt
    14761 tacggggaag catttggaca ttctacagga catgggatcg gtttagagat ccacgaagga
    14821 ccaaacgttt cttctcgtgc agaaaagcaa tttgtaccag gaaatgtgat cactgatgaa
    14881 ccagggatct acttaccagg aatcggtgga gtacgtattg aggatgactt gttgatcaca
    14941 gaagatggaa atcgtgtgtt gactcgttca ccaaaagaat tgatcatctt atagtttcat
    15001 caatagaaga agtaagcgta aaaatcagtg ttcacagact ttgttataga aaatcactcg
    15061 atttaatgat acactataga agaactttta agctgtaaga gataataaag ttgggtgttt
    15121 tctccaattc atagcagttt gcagctgatc ggcggcagtt ttcttaccac gtgatcacta
    15181 tgccgcatca tagagaattc ggatgtatct cgtgcttagg caaagggagg aataaataaa
    15241 tggcagatga aaaaaatttg attttaaacg caaaccaaga tttaggagag atcgtgatcg
    15301 ctcctgaagt catcgaagta attatcggga ttgcagcttc taaagtagaa ggcgtatacg
    15361 gaatgcgcgg aacttttgcc agcaatgtca ctgaattatt aggacgtgca gctcacggaa
    15421 aaggtgttta cttagcaaac gaggaagatg gcttgaaagt agatctttac tgttatctag
    15481 aatatggtgt ttcagttcct aaagtagcaa tggaaatgca ggaacgggtc agccagcaag
    15541 tccttttcat gacggatatc gatttatctg aagtcaatat ccatgtagta gctgttgttc
    15601 ctgaaaaatt agaacaacca acaatcgaag aactttttga agacgaagag gaagagaatg
    15661 aataaagaat tatcaagaca cgagattcgg gaaatggcat tgcaggcttt atttccatta
    15721 gacttcaatg cagacctaac aaaagaagat gcgattttca acgcaatcga attagaccac
    15781 cgcgacatga tcaacgaaga tgaatcagag tttgttcctg tttatcttga tacgctagtt
    15841 ggcggtgtct gtgcaaaaaa agatgaattg gataaagtga ttgaaaaaca tttaaaaaac
    15901 aattggcaca tcaatcggat ctcaaaaatg gatttggtga tcttgcgtat cgcgattttt
    15961 gaaatgactt atgtgacaga tgtaccagcg gctgttgctt taaatgaagc aatcgagttg
    16021 gcaaaaacat ttagtgatga ccgttcacgt aaattcgtca acggtgtttt atccaatgta
    16081 ttgaaagaat tagaagctgg ggcgtaagtc ctagcttttt tctatgaatc atcataaacc
    16141 tgttataaat cgggaaaatt ctatggtaga atgaaaacac aaaaaatatc tgggagtggt
    16201 tagatggcag aattgattaa cggaaaagaa ttagctgaaa aaatgcaggc agagattgct
    16261 gaaaaaatcc aaaaattgaa agataatggt atccatcccg gattagtcgt tttattggta
    16321 ggggaaaatc cagccagcca aatctatgta agaaataaag aacgtgtagc aaaagaaatc
    16381 ggaatccatt cattggtaga gcgttatcct gagacgattt ctgaagacga actacttgca
    16441 gaaattgaaa aatacaatca agatcctagt tttcatggta tattggtcca attaccattg
    16501 ccaaagcata tagatgaaga aaagatcctg ttagctatcc gccctgaaaa agacgtagac
    16561 ggttttcatc cgatgaattt aggcagactc cttgcgggta aaccggacaa gattccttgt
    16621 actccatacg gcatcatgaa aatgtttgaa gcttattcta tcgatccggc gggtaaacga
    16681 gcagtagtta tcggacgaag caatatcgtc ggtaaaccga tggctcagct actcttgatg
    16741 gcagatgcaa ctgttactgt tgctcattct aaaaccgaaa atctggctga actggcacaa
    16801 gaagcagata ttttagtcgt agcaatagga cgtggacatt ttgtcacaaa agaattcgta
    16861 aaaccaggtg ctgtagtgat agatgtaggg atgaatcgtg atgctaacgg taagctgatc
    16921 ggtgatgtga aatttgatga agtggagcct attgcaggct ggatcactcc tgtgccaaag
    16981 ggtgtagggc caatgactat cacgatgctg atgtatcaaa ccgtaaaatc tgccgaagct
    17041 tttggagcag gtgaatagat ggcacaagaa tatttaactg tcactacatt aacgaagtat
    17101 ttgaaaagaa aatttgatgc cgatccttat ttagaacgcg tatatttaac aggcgaaata
    17161 tcgaatttcc gtttacgtgc caatgcccat caatatttca gcttaaaaga tgaccatgca
    17221 aaaatatctg ctattatgtt caaaggagca ttccaaaaat tacgattcca gccaaaagaa
    17281 ggaatgaaag tccttgtcgt tgggcgtatt tcattatatg aagcgggagg ttcttatcaa
    17341 atctatgtag agcacatgga gcctgatgga ataggtgctt tatatcaaga attggaagaa
    17401 cgaaaagaaa agctgatgaa ggaaggcctt tttcaagggc ctaaaaaaat gctgccacgt
    17461 ttcccaaagc gaatcgcggt ccttaccagt ccaagcggag cggttatccg cgatatcatc
    17521 acgacggtga aaagaagata tccaattgtc caattggttt tgttcccaac agttgtacaa
    17581 ggaaaccaag cagcggacaa tgttgtcagg aatatccaga gagtagaaga gatgggcaat
    17641 ttcgatacaa tgatcatcgg tcgtgggggt ggttcgattg aggatttatg gccgtttaat
    17701 gaagagcggg ttgctcgggc gatttatcaa gctaatacgc cggtgatttc atctgtagga
    17761 catgaaacag ataccacgat cgctgattta gtagcagatg ttcgggctgc cactccaaca
    17821 gcagctgcag aattagctgt tcctgttttg tcagaagagt tgatgcgcat tcaagaacgg
    17881 caagctagat tgcagcaggc gtttgtacgc cagatccagc gcaaacaaga acggttcgag
    17941 cgtgctcgac gttcctatgt atttcggcag cctgaaagat tgtatgaagg tcagaccatc
    18001 aaattagacc agttgaaaca gcgattatat caagctacac agcaaattta tcatgcgaaa
    18061 gaaaaacaaa cgatcgcatt aagccaccaa ttggaacaag tggctccgct ttatcgagtt
    18121 aaagcagctc gccaagaaac tgcttatcta gaaaaacgct tagaagagaa aatccaacaa
    18181 tatatgaaac aacagcagca gcgttttgct caagctgttc aatctcttga tttgttgagt
    18241 ccattgaaaa tcatgggaag aggctacagc tatacgacgt taaatgatca agtagtaaaa
    18301 agtgtcaccg agattcatca aggggatttg ctgacgatcc attatcaaga tggaatcgtt
    18361 aaaggacaag tacaagagat agacaaagga gaataaaaat atggaaaatc caacttttga
    18421 agagtcactg caagaattag aaaaaattgt catgcagtta gaacaaggag acgttccatt
    18481 agaatcagct ctagattcgt ttaaacgagg aatggaatta agcaaacatt gccaagatac
    18541 attagctaaa gcagaagaga ccttgacgaa aatgatgaca gaatcaaatg aagaagttga
    18601 ttttgacgga aacgaggaaa gctgagatga gattaactga cttttcagct attcatctac
    18661 ctgctgtaga aaaagaaatc ttgtcttttt tagatgagca tacaacggat agaggactct
    18721 atgatgcgat gagttattca gtgaaagcag gcgggaaaag aatacgtccc ttattacttt
    18781 taacggccgt tgcttccttt gatgagccta ttgatgttcc cgtctatcaa gtagcagctg
    18841 ctttagaaat ggtgcatacg tattccttga tccacgatga tttgcctgcg atggacaatg
    18901 atgatcttcg tagaggaaaa cctaccaatc ataaagtatt cggcgaagca ttagctatat
    18961 tggccggaga tggtttgctt acaggagcat tccagctaat cagtatggca cacttaggta
    19021 attctcctaa gcttctgctg cttcagcaat tagctgtttg tgcgggatca caaggtatgg
    19081 ttgctgggca agctgcagat atcgagggcg aatcgaaaaa gctttcttta gaagaattag
    19141 catttattca tgaaagaaag acagggcatt tgattcgtta tgccttgctg gctggtggca
    19201 tattagcgaa gcaacctgaa gaaatcttat tgctacttca acgattagcc gaacatttag
    19261 gtttagcttt tcagataaga gatgatctac tcgatgtgat tggtacaacg aaaacattag
    19321 ggaaaacagc tggtaaagat gaacgtatgg aaaaaaatac ttacccgcgt ttattaggcc
    19381 tagaaaagac acgtgaggcg ttggagattg agctgttatc cgccaacaag atcatagaca
    19441 aattagaaga ggacgttttt tcttttgatg gcgggctgat gcgccagatg atcaagcaat
    19501 ttgatgtgga gaaatgaggg aaagaatgga aaaagaacgc gtagatgtat tagcggtcaa
    19561 acaaggatta tttgaaacaa gagaacaagc caaacgttca gtgatggctg gtttgattta
    19621 caacgaaaaa aacgagcggt ttgataaacc gggagaaaaa attccagtga gtagtgaatt
    19681 aagagtcaaa ggtaaaaaac ttccttatgt ttctcgaggg ggattaaaat tagaaaaagc
    19741 actcaaagca tttgatctat ctgttgaagg aaaaacattg ttagatattg gtgcatccac
    19801 tggcggattt actgatgcag ctttgcaaaa tggcgcaaaa atgagttatg ctttagacgt
    19861 tggctacaat cagctagctt ggaaaataag acaagatcct agagtcgtcg taatggaaag
    19921 agtgaatttt cgttatgcaa aacccgaaga ctttacctta ggaattccag aagttgctgt
    19981 tatcgatgtt tcttttattt cactaaaact gatgctgcct ccattacatg ctattttaaa
    20041 agaagaggga gaagtgattg ctttaatcaa accccaattc gaagcaggca gagaagctgt
    20101 agggaaaaac ggaattgttc gtgaccctca gacccatcaa aaagttttag aagacatttt
    20161 gtcatttgcg gcacaaggtg gatatgatgt gctggaatta agttattctc cgatcacggg
    20221 gggagaagga aatatcgagt tcttggctca cttgaggaaa gtacccgaaa gcggaacaat
    20281 caattcagct attaatatgg cagaagtggt ttcaaatgca cacgaacagt ttgaccataa
    20341 ataaattgta actgtgaaaa tcaagtgaga agtatgcgga ttcttcttta ttataccaag
    20401 gaaataagct atcattgatt aagaagaata tgctaaggag cgaagacgta atgagaaaaa
    20461 aagatcggca tcgtttgatt actcgattgt tgagtgagca agatatccga aagcaggaag
    20521 aatttgttga aatcctgaaa agcaaaggaa tatctgttac tcaagctacg atttccagag
    20581 atataaagga actgaaactg atcaaggtac cggcttcaga tggcggctac cgttatagca
    20641 taccagctga aacaaacgaa gatgtaaata ctaaattgga aaaactatta aaagacgctt
    20701 tcgtggcagt tgaccaaatg gaaaaatttg ttattttgaa aacattgccg ggaaatgctt
    20761 cggcagcagc aaatttgatt gataaacgtt acaagaaaga attattttcg attatcaatg
    20821 atgacgataa tgttttgatg attacacgaa ctgaagacca ggcagtttta ttgaagaaag
    20881 acttcctgca ttacctttaa gttgaggagc gaatgtgatg ctacaagaaa tcagtattac
    20941 taactttgcg attattccgg aattgcggct ttcttttcac gaaggaatga ccgcgctgac
    21001 cggagagact ggtgcgggta aatccattat tatcgatgct ttaggtctgt tagcaggagg
    21061 aagaggttca agcgattata tacgtcaagg agcagaaaaa tgtgtgcttg aagggttgtt
    21121 tgaactacca aaacaagaag gattctctga actgatggtt gaattaggga tcgaaacaga
    21181 tgaggacaat ctgattgttc gacgggatat gtccttaact ggaaaaaatg tttgtcgagt
    21241 gaatggtcat attatcacat tagctaatct gagaagaatc ggcagttatt tagtagatat
    21301 ccaaggacaa aacgaacatc aggaactgct ccagcctgaa tcacatcttg ctttattgga
    21361 tcgttttgga gatgtagctt tccaacagaa gaaaaagagt tatcagcaag aatatatctc
    21421 ttatcgtgag ctggaaaaaa gggtacgaaa agtgcagcaa aatgaaaaat cctatgttca
    21481 gagaatagat atgctccatt tccagcaaga agaaatagct gctgctgatt tgcaagtcgg
    21541 agaagaagag aaattaaaag aagaaagaga aaaacttagc aattatcaaa aaattgctga
    21601 tggattagct gcaggttacg gagcactgac gaataatgaa caaaacagtg tagatggtgt
    21661 tggcttggcc gtttcagaac tgcaagggat cgcccatcta gatgtggagt atgaagcaat
    21721 ttatgaaaat atccaaagtg cttactattt gctgcaagat gcaatcggcg atatgagtcg
    21781 tcagattgat ttattggagt tagatgagag tcgtttagaa gaagttacgc aacgtttaga
    21841 attaatccga cagttgaaac gtaaatacgg cgaatccatt gagtcaatat tggcttacta
    21901 tgacgaaatc accgaagagc tagcttcttc tgatttttca gaaggtcaat tggacaaaat
    21961 gaaagaggaa ctagagcaaa aagagcttct acttcagcaa caagccgcag atcttcatga
    22021 agcgcgtaaa aaaatcgcaa aagaattgga aaaatccatt ctgcatgaat tgaaaagtct
    22081 gtatatggaa aacactgagt ttgaggtacg tttcttaaaa gaagaaaata gacaattgaa
    22141 tcatgatgga tttgaccaaa tcgaatttta cattacgacc aatccaggag agccactgaa
    22201 gcctttggtg aaagtcgctt ctggtggcga actgtctcgg atgttgcttg ctttgaaaac
    22261 tattttttct tctgagcaag gtgtgacaag tattattttt gatgaagtgg atacaggtgt
    22321 gagcggaaga gttgcacagg ccatcgcaga taaaatttct caaatatcga aatactctca
    22381 agttttgtgc atcactcatc tgcctcaagt tgctgcagtc gccgactatc aatattatat
    22441 tgtgaaagca gtgattgatg gacgtacgca aacttctgtt tcagagttga aaacaaaaga
    22501 aagagaagaa gaaattgcac gtatgctggc tggaagtgag attacaaaac tcacactcga
    22561 acatgcaaaa gaactattga aactcgcaaa aaggacctga gccacctcgc agtggttcag
    22621 gtccttttca gcagctgata gctatatttt a
//
LOCUS       DAXLPY010000043        22531 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.043, whole genome shotgun sequence.
ACCESSION   DAXLPY010000043 DAXLPY010000000
VERSION     DAXLPY010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.043"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..97
                     /locus_tag="ACF3UF_001762"
     CDS             <1..97
                     /locus_tag="ACF3UF_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFD3671872.1"
                     /translation="KKIKGGAGTKPQGKPASNLVECVFSLFKKCN"
     gene            173..1420
                     /locus_tag="ACF3UF_001763"
     CDS             173..1420
                     /locus_tag="ACF3UF_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD3671873.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            1435..2187
                     /locus_tag="ACF3UF_001764"
     CDS             1435..2187
                     /locus_tag="ACF3UF_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3671874.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(2890..3105)
                     /locus_tag="ACF3UF_001765"
     CDS             complement(2890..3105)
                     /locus_tag="ACF3UF_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HFD3671875.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(3124..3360)
                     /locus_tag="ACF3UF_001766"
     CDS             complement(3124..3360)
                     /locus_tag="ACF3UF_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HFD3671876.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            3618..5771
                     /locus_tag="ACF3UF_001767"
     CDS             3618..5771
                     /locus_tag="ACF3UF_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HFD3671877.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            5740..7155
                     /locus_tag="ACF3UF_001768"
     CDS             5740..7155
                     /locus_tag="ACF3UF_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFD3671878.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            7188..8222
                     /gene="sppA"
                     /locus_tag="ACF3UF_001769"
     CDS             7188..8222
                     /gene="sppA"
                     /locus_tag="ACF3UF_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFD3671879.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            8224..8745
                     /locus_tag="ACF3UF_001770"
     CDS             8224..8745
                     /locus_tag="ACF3UF_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFD3671880.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            8742..9128
                     /locus_tag="ACF3UF_001771"
     CDS             8742..9128
                     /locus_tag="ACF3UF_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFD3671881.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(9624..9696)
                     /locus_tag="ACF3UF_001772"
     tRNA            complement(9624..9696)
                     /locus_tag="ACF3UF_001772"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9661..9663),aa:Lys,seq:ctt)
     gene            10077..10646
                     /locus_tag="ACF3UF_001773"
     CDS             10077..10646
                     /locus_tag="ACF3UF_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFD3671882.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            10633..11493
                     /locus_tag="ACF3UF_001774"
     CDS             10633..11493
                     /locus_tag="ACF3UF_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3671883.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            11683..12387
                     /gene="yycF"
                     /locus_tag="ACF3UF_001775"
     CDS             11683..12387
                     /gene="yycF"
                     /locus_tag="ACF3UF_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFD3671884.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            12392..14227
                     /gene="walK"
                     /locus_tag="ACF3UF_001776"
     CDS             12392..14227
                     /gene="walK"
                     /locus_tag="ACF3UF_001776"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFD3671885.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            14224..15540
                     /gene="yycH"
                     /locus_tag="ACF3UF_001777"
     CDS             14224..15540
                     /gene="yycH"
                     /locus_tag="ACF3UF_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFD3671886.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            15541..16410
                     /locus_tag="ACF3UF_001778"
     CDS             15541..16410
                     /locus_tag="ACF3UF_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFD3671887.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            16465..17274
                     /locus_tag="ACF3UF_001779"
     CDS             16465..17274
                     /locus_tag="ACF3UF_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3671888.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(17377..18006)
                     /locus_tag="ACF3UF_001780"
     CDS             complement(17377..18006)
                     /locus_tag="ACF3UF_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3671889.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            18176..19468
                     /locus_tag="ACF3UF_001781"
     CDS             18176..19468
                     /locus_tag="ACF3UF_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3671890.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(19544..20206)
                     /locus_tag="ACF3UF_001782"
     CDS             complement(19544..20206)
                     /locus_tag="ACF3UF_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFD3671891.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            20431..20715
                     /gene="groES"
                     /locus_tag="ACF3UF_001783"
     CDS             20431..20715
                     /gene="groES"
                     /locus_tag="ACF3UF_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFD3671892.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            20766..22391
                     /gene="groL"
                     /locus_tag="ACF3UF_001784"
     CDS             20766..22391
                     /gene="groL"
                     /locus_tag="ACF3UF_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFD3671893.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         7718 a         3583 c         4480 g         6750 t
ORIGIN      
        1 taaaaaaatt aaaggaggtg ctggaacaaa acctcaagga aaaccggcat caaatttagt
       61 ggaatgtgtt ttttcattat ttaaaaagtg taactaaaat tttttttatg atatcctaaa
      121 atcaggaggg gatctcttga ttactatcga tacaaaagct tatctattaa gaatgttcgt
      181 gggaaacttt ttcttttttc tcttatttta tatgactaat actgatctta acaaaagaaa
      241 atatcttttt gtatgtttat tgataccact cacttttttt gttgaattat ttactgatgt
      301 ttccgcagct atacctataa tcggaagtta ttttatatta aaggaaaaga agaaaactaa
      361 tatagtgctt ttaaataaat tactattatg tatgcttatt gatgatttca gatctattat
      421 tacttccatg gttatgacgt atatgttttc atttgaaggg ataaaagggt atggttatgt
      481 agtattccag ataatgcttg attctttgtt tttgctgatg tttatttggt tatatagaaa
      541 attagctata aataggattg ttgaacagtc cagttctaaa cttactgcta tattcatgat
      601 ttatttactt acaattggtt tatttgtttc ttatgttgct catcaatatc aagtatttga
      661 tcattttgtg tttggtgtct taatattttt aatcattcaa atgtttgttg ttctattttt
      721 atttattaga ataactatta ggcaacgaga acaatatgaa cagcaattga aaagaaaaga
      781 attggtttat ctaaaaaaat atactgattc actggaaaaa gatcaagaaa aatttgccag
      841 atttagacat gactataaaa atttattgct gagtttaaaa gaaatcgcta atcaaaacca
      901 tgattcgata ttggaaaaag aaataaaaga attagagatc tattctaatt cttatctaac
      961 caataagttt gaatatcgtt atttaaaaaa tataaaaaat gaatatttga aaagtttgtt
     1021 gatagcgaag ctataccaag caaataacaa taagatttgt tgtaaattcg aatgtccaag
     1081 tactattatt gaagttcctg ttccaatatt tgactgtatt agggtgcttg gaattattct
     1141 cgataatgca attgaagcat ctatagagag tcaagataga gaactgtctc tagctattta
     1201 ccgagatgat aaacagatag aaatttcgat atcgaatagt tgtagagaga tactactctc
     1261 tatagatact ctaatgaaaa aaggaataac aacaaaaaag ggacatcaag ggttaggttt
     1321 atctagtata gaggaaatca ataaaaagaa tcccaatatg tttgtgaact atcaaaacga
     1381 tccgtatcaa tttactactc aagttatttt gttgttttga gggaaggagg atttatgagt
     1441 tatccaataa tattatgtga agatcaaatt atacaattaa atcagttaga acgaattatt
     1501 gataatttca ttctttttca cgataaagta tttaagatag tattgaaaac acaaagtccg
     1561 ttagaagtta aaaaatacct caaacaattc cgaccaaagc aaggaatata tttcttagat
     1621 attgatttaa atcatgaagt taacggtata gaattagcag aagtaatcag aaaatatgat
     1681 gttcaagcaa aaatcatttt tacaactact catgatgaga tgttacccgt aacaataaaa
     1741 agaagagttg aaacgttagg atttgtaaca aaagatcaaa cactagatga gtatcgaaac
     1801 gagattgttg agttattgtt attagcgcaa gaaaggatag atgcaacaaa acaggttacg
     1861 aatcaagcat ttgttttttc cataggttct caaacattta cttttgatat aaatgacatt
     1921 tattttgtag aagcttcaaa attaccacat agattatcat tgtgtactaa agatgggcag
     1981 tacgaatttt atggaagaat tagtgagctt gaaaagaaat atcctatgtt aacaagaatt
     2041 agtcgagcgt gtttagtaaa tatctttaac gttaaagaaa tagattttaa aaaacgttca
     2101 ctatattttg attcagagtt ggccagaaac tttactttag ggaaagcaca aaaaattaag
     2161 gagaagttga aagaaagcac tgtttagtgg ttttttcttt agggagattg catttttcta
     2221 ataaaataga ttccttcact agtgcaaatt tttctgaatc ctattaaagt tgtaccaatt
     2281 tttatagctg ttattagtta cgtgcataac agcaatatta gttactggag gaatatttct
     2341 atggtctgga accaaaaaag ggccaaatga atagttcttt tcttgttttt attaagtacc
     2401 ataaagggga attaaaatta aatgtatggt ggaagatgcg aaagatttgg caaattctac
     2461 taatttttag aaagtgtttt tcatttttta gttaaaaaat ttgtcctgtc aagtgcaatc
     2521 ctatgattgt acttgatagg atttgagata attactttcc tgtttttata aatttaactt
     2581 gcaggaacag gctttaatgc acatccgaca agtacattac caatacctcc tgtaacggcc
     2641 gaaataggtc ctcctgcagc accaactaca gcgctgcaag tccttttgta aaaatatctc
     2701 taccattaca tttccaaaga atttttatct gactttaata aaagataaaa atttaatata
     2761 attataaaaa ctagcacaag aagctttagt aaaaagttct gtccattcca aacttttgaa
     2821 aagataaaga acatacctat gttcgtaatc gacacaaacc aatcttgagg tttgatattt
     2881 tttaattgtt tacgcaccgg tccacatgct gaatccagca cctaataaag ctccacctac
     2941 accacaagca gctattgcat aaggtcctcc ggctgaacaa agttttactc ctgctgttgc
     3001 cccagaaaaa gtagtgccta aaactcccac ggcactccca ccttgaatat ttttcaactc
     3061 ttctgaagat aatataaatg ttgtttttgt gtttttaata tgcatactac ttattctcct
     3121 tttttatttt tttcgagcat cccagccagc tgcagcacct ccagcgacag ctccatataa
     3181 ccctccaaca acaccgcaag ctggtccgca aattgctgtt cctaaacctg caccacctac
     3241 tgcccctgtg gtaagtccac ctacaacttg ccccaatttt ccccaagcat tattgcctcc
     3301 accaacagtt tgtgcatttc cacaatactt agttccttta cattttgcat gtttaaacac
     3361 gcttctttaa ataatatttt ttacggtgct actgtaacat acgtatttga ttaacagtaa
     3421 aaatcttcct gaaacttatc aagtttattc ttgaatagta aaatttccaa aataaatttg
     3481 attcaggaat gaaaaagtta gtgttcaaga actgttttca aagtttttgt ggaattatga
     3541 gacaatattt tcactgtatt aaagctatat tgagaatttt tctataaaaa ttttttagaa
     3601 ggagttgtgt tagataagtg ataaaatcat ttccttttgt gcagcaacaa gatgaaaaag
     3661 attgtggtgt tgcttgcctt tcgatgattt taaaatattt taaaactgat atcccgattc
     3721 ataaattacg ggacctatct gggactgatt tagagggtac ttcagcattt ggattgaaaa
     3781 agacatttga aaaattgtct tttgattgta tggctattca agcagatagt gagatctgga
     3841 aagaaagaga tcttatctta ccattaattg cacatatatt ggttgataac agctatatgc
     3901 actacgttgt aatttataaa acgaagggaa acgtactatg gattgcagat cccgctaatg
     3961 gaaaaaatag aaaaacgatt gaagcgtttc aaaaagaatg gacaggtatt cttttattac
     4021 ctatgcctag agaaacttat attcctatta aagaaaaagt agctggatta agttcttttt
     4081 tgcctataat ttggaaacaa aaaggattag tattccacat cgttttagca tcgattttca
     4141 ttacgttttt tggcatagga agctcatatt attttcaagg tattcttgat tttttcatcc
     4201 ctaatcaagc acgttcaact ttaaatataa tttccattgg cttgatcgct gtctatttat
     4261 ttcgggtatt gtttgaatat agtcgtagtt atcttcttat tattttagga cagcgaatga
     4321 gtatggcaat tatgcttcag tatttcaaac atgtgttaac tttaccaatg aatttttttg
     4381 ctacgagaaa atcaggggaa attatttctc gttttcttga tgccagtaag attattgatg
     4441 ctttagcaag tgctacgtta tcaatatttt tagatattgg tatggtgttg cttgttgggg
     4501 ttacgttagc tattcagaat agtacgttgt ttttaatcac tctatgctct ttgccttttt
     4561 atgtagttgc aatattcgct ttcgtgaaaa gctatgaaaa atcgaacagg gaagaaatgg
     4621 cagccggtgc agctgtaaat tctagtatca tagaaagtct taaaggaata gaaacaatta
     4681 aagcatatag cggtgaagag aaagtatata accgtataga ccatgaattt gttaaattaa
     4741 tgaaaaaatc atttcgtacg gttacgcttg ataatattca acaaggaatt aaacatttga
     4801 ttcaattaat tagcagtgca ttaattttat ggctaggttc ttattttgtt atggataata
     4861 gaattagtct aggtcaactt atcacataca atgctttact agtatttttg acagatcctt
     4921 tacaaaacat tattaattta caagtgaaaa tgcaaacggc tcaagttgca aataatcgtt
     4981 taaatgaaat tttcgcgatt gattcagaaa aatcgaacca gtcttttgaa tatatgcttt
     5041 ctgaacaatt atttcaacaa gatatcactg taaaaaacgt ttcattctcg tatagcatga
     5101 aggccccaac gttgaacgaa atttcatgta caattccttc gcacagtaaa acggctatag
     5161 ttggagttag tggttctgga aaatcaactc ttgcaaagtt atttgttcgt ttttatgaag
     5221 catcagaagg atcgatccat tatggaaaca ttaatcactt agacattcct tttcagatat
     5281 tacgcgatcg agtgacatat ttgcctcaag agtcattttt ctttagtgga acaatcattg
     5341 agaatcttat attcggttta gatagcccac caagtttcga acaaataata gaagtttgtg
     5401 agatagtcca actaaatgaa tttattaatc aacagccatt acgttacgag acattgttgg
     5461 aagaaggtgg aaataatctt tcaggagggc aacgacaacg attagcctta gcacgggctt
     5521 tattaaaaaa tccggacata ttaattttag atgaagcaac tagtggatta gataccttgt
     5581 tagaacatgc aattatgaat tatctcctca atttaaaaga aaaaacgatt atttttattg
     5641 cgcatcattt accaatagca aaagcatgtg atcaaatttt agttctccat gaagggcatt
     5701 tggtagaaaa aggaacgcac gatgaacttc gttttgccga tggtatctat caaaaattat
     5761 gggaaatcta ggagagggaa acaatttatg cagaataata attggttcga acattctagt
     5821 atctatacta aacaacatca tagcttctac cgttgggtgt tataccctgt aattcttttt
     5881 ttatgtatta ttggattgtt tttaaccttt gctaaaaaag aggttgttat tcggacaacg
     5941 gctcaattga accccgaaaa aatagagaag ttacaagtgc cattagaagc taaaataatg
     6001 gaaaacttcc taaaagaaaa tcaatttgtt cataaggacg atgtgttggt tagattggat
     6061 tgttctttaa tagagaatga aaaggctcag atagaacaag aaaaccaacg tattactcaa
     6121 caaataaaga tggctcagct atttattgaa agtataagta aaggaaaaaa tttgttttca
     6181 acggatgaca gttttggcta cagtaatcaa ttaaagagca tgttgtcaga aaaagaatca
     6241 ctccgctacg ctttgaagca aagtgaatta aatgatcaaa agcaattaga agtatacgaa
     6301 aagacaaaaa gacaactaga aaaacaaatt gagagttcag atagtaaatt acaagaatgg
     6361 caacaagtac aggtagcttg gagtaataat caatcattaa aagatttttc aaaagaaatg
     6421 atggcaaact atgagaattg gcaagaacaa ctaaataatg tttctgatga tcaaaaaaat
     6481 caagtgaaac tgacaatttc agcaagcata aatgaacaaa ttgagcaact aaaaaaagaa
     6541 gtagaacagt atcagtcaga aaaagctaaa ttagttaaac caactacttc tgagaatgac
     6601 agaattagtc aaacggaaaa aggaaagcaa gagctagaac aagcaataac aactgtaaaa
     6661 caaacagtta cagagctaaa tgaaaaacaa gagaagaacc agtcagttat caaaagtttg
     6721 gacgatcaac tttcaaaagg aatactaaaa gctcctgtat ctggaacggt tcatttaaat
     6781 gaagaaacaa agggacaagc agaactagcc aaaggaacag tgcttgcaga aatttatccg
     6841 atccacgaaa aatcaaaaat gaaatttaca gcacttttac ctgcgaatga aagtacctat
     6901 attaaagaag ggatgaaggt tcattttaaa ttggatcaaa aaggtggggc tccgattacg
     6961 atcgacggaa ctttagatga aatttcagaa aattctactg ccactgagaa aggtgttttt
     7021 tatgcagtga aaggaacgtt aaaaacaact caatcgtttc cgtttcgtta tggattaact
     7081 ggagagttgt ctttaattgt aggagaaaaa acatattggc aacaaattgt cgatgtgttt
     7141 ctaaataaaa aataattatt tttactaaga atataggagg agtttatatg aataaaagaa
     7201 gatggattgc tgtgggagta gcgtgcggat tattgttact atccattatc gtcgcgctaa
     7261 ttccaggaaa agataaagag gaagcatcaa atacaaccct aacaggaata aataagattt
     7321 tttacggatc taacgaaatc acagaagaaa cgttagaaga aggcgcatca aataaaaaga
     7381 ttgtcaaact atccgtcaat ggagttattg cagatacagg tgaaagcaat ctttttagta
     7441 gggaacaata taaccatcag aattttttaa cacagctaaa gaaaattcaa gaagacaaag
     7501 cggttaaggg agtgttatta gaagtaaatt cacctggggg aggaatatat gaaagtgctg
     7561 agattgctaa agaaatggca aaaattaaaa agctagatat tcctatctat actgcattta
     7621 aaaatacagc ggcaagtgga gggtactaca tttctgctgg ttcagataaa atatttgcta
     7681 cggaagaaac aacaactgga tcaattggtg tcattatttc tggtttaaat tattctggct
     7741 tattagaaaa acttggcgta actgatgcga cgtataaaag tggtgcatta aaagatatga
     7801 tgtcacctca acacaaacct tcagaggaag agaataaagt tatacaggaa tttgtgatga
     7861 gtgcttatga tcgttttgtc aatgttgtag caaaaggaag aaatatggat actaatgcag
     7921 tgaaagaact tgcggatgga agaatttatg atggtaacca agcagtagaa aatgggttgg
     7981 tggatcaaat tggttactct gaagatgcat tagattccct aaaaaaagag aagaaattaa
     8041 ctgatgcgac ggttatagaa tataaaaatg acacaactgg ctttgcttct tcttggttag
     8101 gtaataagat tgctgaatgg caagggctaa aggcaactac atcagatcgt gtaatttcag
     8161 tttttgaaaa acttggattt tctgatactc caaaaccaat gtattactat ggagggctat
     8221 aaaatgaata agaagagtgg cattgaaact ttgcctaatt atgtatttgc gggattttgg
     8281 ttacgatttt ttgcttttct tattgattta atttgtatta gcatcatcac ccatgctact
     8341 ataggtctct tttacaaaat catgggactg gaatctgaca aatccattat tactttttat
     8401 ggtatagcgt cattagctat ttatttaacc tattttgtac ttttgactaa gctgaattca
     8461 ggacaaacaa ttgggaaaat gatttttggg ataagagtag tgagctttga ggaaaaagag
     8521 ctaagttggc aaactatctt tattcgtgag tgtatatgta ggtttatatt aaaaaatttt
     8581 gtatttcaaa ttgggtattt ggtggctgct ttcacgccca agaaacaaca tattggggat
     8641 tatttttcta acacgtcagt ggttgttatt cgttcattag aagctattaa ctatggtcaa
     8701 aaaatttcta attctaaaac acttaatctg gagagaatta aatgaataag agaaaaacag
     8761 agtttatttt gattttaatt agtggaataa cagggatttt atgtagtctt ttagcattga
     8821 tgggtggtat gtttctatct tctattgatt caactacttt aaatactaca gaactaacca
     8881 gtaaggatat agatatgtta gtcaatctaa gcgggaatgt tgttttattt ggaggaatta
     8941 ccctagtttt ttcgataatg attttcataa taggtttttt agtaagaaaa aatcaaaaaa
     9001 cagtggtcta tggtattagt ttactcattt tatctattat tccatttttt cttttaacat
     9061 tattgtgggt aattcctgga gttttaggta ttattgcggg attgatgctt ctaataagaa
     9121 aatcttaatt aggcaatgtg tagacaacgt gaaacgatta atcaattaaa agctaaatac
     9181 gttttgagaa atgataactt gtagtcgatg gaagacatgt agataaaaaa actacgtgtc
     9241 ttttatttat tctaattttt tcgaaaaaaa gacactctct gattgttgta ttaatggaaa
     9301 aggggaaagc agcaagtaaa tttagttttt ctattaaata ttcttcactt tttaaccttt
     9361 tatagtactt agatttaatc ctatatgttt agagagttca ttggcagcat gattttgcaa
     9421 agcttctcga attattgtta tattagaaac tttactgttc ataattatgc ttctttttta
     9481 actcaaagtc caaagggcta cagtggactt tgagttaaaa ataaaaagcc ctagttattt
     9541 tgaaaaataa aaaaagaaca gcgtaaatgt tttcgaaatg ctttcgcacc aacatttacc
     9601 tgttccgtgg gtttggcacc caatgggccg tgaggggctc gaacccgcga cccgctgatt
     9661 aagagtcagc tgctctacca actgagctaa cggcccgtac aaaaagtact taataatagt
     9721 agcactaaga attttaaaat gcaagactac atttaaagaa aatcagaaaa atctttactt
     9781 ccttatagga aatcattcat agattattca catttgctcg ctattatata agcataccaa
     9841 caaacaaagt tcttgcaaga gaacaaaccc taacactttt ttcatttttt actcctttcc
     9901 cgccgtctcc ccggcgggtc tcctgttctt aacgataaaa gacaagaagg cttagccttc
     9961 ttgttttttg ttttcataga atcccgctaa tcaaatcacc tagttaaagc aactagattg
    10021 aatgtttatc ataagtctga tatcatgttt atgaaatgaa aaaaggagcg gttatgatgg
    10081 aaaaaatgcg tcagcaatta atggagtggg ggaaggaact agaaacattc cgtctgcctc
    10141 actgggaaga actccctgac ttagaacttt atatggacca agtcagaacg ttagttgatc
    10201 gttatctttc acctgtgata caaggagaaa agcatccatt gcttacctct tctatggtaa
    10261 acaattacgt taaactaggt ttgataccag caccagttaa aaaaagatat aacaaagaac
    10321 acgtagcatt tttacttgca atcactacgt tgaaacaagt attgactatt cctgaaatca
    10381 aagaagggat attgttccaa ggaaaaacag taggaattcg tgaagcctat aatctatttt
    10441 gcgatgaaca agaagcagct gtgtggatgg tcagccaatt agcacaaggt aaatctcatc
    10501 cgcaaaaatt cgaccaggca acccctgtag aatatattgc tgtaagagcg gcaactttat
    10561 cgtttgcaat gaaacttctt gcggaaaaaa cgattgttct agaaaccgaa tatttaaaag
    10621 aggagaaaac aaatgaaaaa caataaaatc gcaattttag tagattcagg tacggatgtt
    10681 ccagaagaat tgataaaaaa atacgagatg tatatgatcc cattgaaaat tatttataaa
    10741 gatcaggtat atacagataa aattgacatt acccctgaag agatctatca acgtttgcca
    10801 gaggaaatcc ctggtacatc tttgccggat ggtgagtcga tcacagaaat ctttgagcaa
    10861 atcaaaaaag acggttatga aaaggtactt gcggtaacaa tttccagtgg attgagcggg
    10921 acatataatg tggttcgttt aattgcacaa cagcaagaag aattggaagc atatgtacta
    10981 gatacgaaaa atattggtat tggtgcaggt ttttctgcga tccaagcagc aaaatggctg
    11041 gaagaaggag tagaatggga tcaactgatc agtaatctga atgagttagt cgaaagaaca
    11101 aaagttttct ttaatgttgc gacattggaa tatcttcaaa aaggtggacg gatcggttta
    11161 gttgcttcta ttgtaggaac cgctttaaag cttaacccaa tcatctcatg taatgaagaa
    11221 gggatttatt acacagtagg aaaagctagg ggacgtaaaa aaagtttgga taaaacggtt
    11281 gcttacgtca aagaaaaaat cggtaatgca aaggtcttca acttagctgt tgcccatggg
    11341 gatgcgaaag aagaagcaat tgaaatggaa gcgagactta aaagagagtt cccacaagca
    11401 aaccaaatct actttggcca gatttctccg gcattagtag tccacactgg tccgggatta
    11461 ttgggtgtcg gtgtacaagt tttagaagga taaatcaaaa aaaggaaaca ctgaggtgaa
    11521 aatcagtgtt ttcctttttt attgaagtta gaacaaaaaa taataaagta ttttgcactt
    11581 tcattttaat tttctctttt gttttatagg caaagatgaa acaaaagcag aaatacggta
    11641 taatgagaag gtatgacaat aatatataag aggtggctct ttatgaaaaa agttttagtt
    11701 gtcgatgatg agaagccgat ttcggatatc gtcaaattca atttagccaa agaaggctat
    11761 gacgtttata ctgcatatga tggggaagaa gccttggaaa aagttgctga ggtagaacct
    11821 gatttgattt tacttgattt gatgctacct aaaatggacg gcttagaagt tgctcgtgag
    11881 gtacgcaaaa cttatgatat gccgatcatt atggtaacag ccaaagattc tgaaattgat
    11941 aaagtcctag gcttagagtt aggcgccgat gattacgtga ccaagccatt ttccaaccga
    12001 gaattagttg cacgtgtcaa agcaaatctt cgtcgcggtg ccacggctgc gaaggaacca
    12061 gaagaggcag cacctgcgga attgacgatt ggtgatttga cgatccatcc agaagcttac
    12121 atggtgacga aacgaggaga aacaatcgag ttaacacatc gtgaattcga actactcttt
    12181 tacttggcga agcaccttgg acaagtgatg acaagagaac atttattaca aacggtttgg
    12241 ggttatgatt attttggaga tgtacgaaca gtggatgtaa ctgtacgtcg tttgcgtgaa
    12301 aagatcgaag ataatccaag ccatccaaat tatttagtga cacgtcgtgg tgtcggttac
    12361 tatttgcgta acccagaaca ggagtaattg gatgaaaaga aaagtccgct tttttcgatc
    12421 agtcaatttt aagatcgcta ttacctttat tctgatttta ttgatctcga tcgaaattat
    12481 tggtgcctac tttatacgtg gtttagaacg ttccacgatc aatacattta ttaaagatat
    12541 gaatcaaacg gtggaatcat tagcaacaac aatcagcccg gaattgaatc gaaaagataa
    12601 tgcagatgat gaagaggtaa atgcgaatat caaaagattt attgaaaaca gtgcgactag
    12661 cgatatcatc gaaatacggg tcgttgacga aaaagggatc atccgaggaa caaccgatgt
    12721 caatgaacaa agcgctgtgg gaaagaaaaa tgattatgtt gatatcaatg atttcacgac
    12781 taaacgttat gttgctttag ataacgacga taaacgggtg aatatcaatg ttcaaccgat
    12841 cctgtccccg accggcgatg ccgttatcgg ggctctttac gtcaaaagta atatcgaaca
    12901 aaaatattcg gaaatcaata acacagcagt cattttcttt actgcctcac taattgcggc
    12961 atttatttca atgatcgtat ctgttttagt tgctcgttcg attacacagc cgatcggtga
    13021 aatgagagaa caagccattc gaatcgctag aggagactac agtcggaaag tcaaagtgca
    13081 tggacaagat gaacttggac agctggctga taccttcaat cagttagctg aacgtattga
    13141 agaagctcaa gatacaatgg aagctgaacg caatcgtttg gatagcgtgc tatcccatat
    13201 gacagacggc gtcattgcga cagatcgcag gggtaaagtc attacgatca atgatatggc
    13261 tgtttccttg ctagatatca aaaacgagga agcaatcgga caatcgattt tgacactttt
    13321 agatatcgaa gaagaatata cgttgcggaa attattagaa gatccaaacg aaatggtact
    13381 tgaccgttca accagtacat tggaaagtga tcagatgatc ttgcgagtag acttttctat
    13441 gatccgtcgc gaatcaggtt ttatcagcgg attagtagct gtcttgcatg atgtgacaga
    13501 acaagaaaaa acagaacggg aacgtcgtga attcgtctct aatgtttccc atgaacttcg
    13561 tacaccgttg acaagtatgc gtagttatat cgaagcattg agcgaaggtg cgtggaaaga
    13621 cgaggaagta gcaccaaatt ttttgaaggt aacgctagat gaaacagacc gaatgattcg
    13681 aatgatcaat gacctcttaa atctatctcg catggataca ggtaataccc agcttcaatt
    13741 agaatatgtc aatttcaacg agttagtgaa ttttgttctt gaccggtttg atatgatggt
    13801 gggaaatcag gaaaaaaatt ataagatccg tcgtgaattt acgcaaagag atctttgggt
    13861 cgaagtagat acagataaaa tcatccaagt agtcgataat atcatgaata acgcgatcaa
    13921 gtattcacca gatgggggaa cgattacttg tcgcttatta gaaacgcata ataacgtgat
    13981 tttaagtatc accgatcaag gattggggat tcctaaaaaa gatctgaacc gagtgttcga
    14041 gcggttctat cgagtagata aagcacgtgc aagagcacaa ggtgggacag gacttggatt
    14101 agctatttct agagaagtga ttaaggcgca tcgaggcgct atttgggcag agagcaagga
    14161 aggaaaaggg tcgacttttt atatctcgct gccatatgaa ccttatgagg aggaatggtg
    14221 ggaatgagaa tctctgaaaa agtcgttcgt ataggactca ttttgatggt tgcgttaagc
    14281 atatacttct cttatgcaat ctggctgagc ccagcaggaa aaagttcaat caacgtagat
    14341 gagacaaaca ctcaaatgat cgagtctcaa agcaatcgaa aaacttccga agtctttctt
    14401 ccgcttcatg ttacatggca ccattcggga atgatccaag aaaccaacag tgaaaatctc
    14461 gtgtaccgat tgcaattgat catcgataaa gcaagatttg gaaagctttc tgaagtagtt
    14521 tcaggagaca aatcacagtt tgaacaggtg aaaaatctga actctggttt tgagttggcc
    14581 tataatgcgc cttttttgct aagagaatac aaggaagcat ttgatttaga tttagatgtg
    14641 tcgaacttgg caaaagaaag cgaaaatatg tattttacta gaatacaatt cgatcaagga
    14701 aataaaaaaa tccgattttt gaattattcg aaccatctcg tatatgaagc aaatatttcg
    14761 ttgaattgga cagatatcaa taaagaatta acagcaaaag acacaaaatg gacagaaatg
    14821 acaacagaac catcgacgat cgacacgcaa tatgctacga aacattcgat caaactgaag
    14881 aagtatagtt atatcctgtc acagcaaccc tatacacttt ttagaaatgc ttttttccag
    14941 aaaccagata gcgtgaaaaa taatgatgaa agcaatgaat tgatttttta cggtgggaat
    15001 gaaacaatgt ctatccattc ggaaacgcaa gtagttgatt ttcgtggaga gctgccagag
    15061 aaaaaagaaa atgctagtgt attttctgaa agtttcccct atattagcaa attaggcagt
    15121 tctttaggga acctcagata ttttgaccgc agtgacaata cgatcgatta tcggatattc
    15181 gtggaaggct tcccggtttt tgggacagac agcagaggac agattggtgt ggaagttggc
    15241 ggtgaaacga atggttctgt gcaagtgaat atccaaacca gtttgaatac gattcaagtg
    15301 ccgatacctt cagacgaaga agtagaactt gcaagtacga atgaaatcat ccagcagtta
    15361 aaagctaagg gagcagatag caacaagatt ggttcagtga tcgttggcta tacatggcaa
    15421 aatgtcaaag aaacgaatcg tgtcgttgat ctcttacctg aatggtatgt gaaatataaa
    15481 gataactggt attcagctaa cgaccttctg gaaaaattac ctggattgga ggcgaattaa
    15541 ttggatttca aaaaaatcga atggatattt ttcgtcgctt ttttagggtt gaatgtgttt
    15601 ttattcagca gttatcatga cgcggtatac caagaaaaca atgtcattcg ctctaatcag
    15661 actgaatcaa tccaacaacg tctggctagc gacgatatca cttacacggg gaagatttcg
    15721 tctgagaaca agcaaggcta ttatcttagc gcggagcaga ccaatcttag cacttcatta
    15781 gcgaattatc gcaaggctgg taaaagcggc ttgctggcaa gtggtgtgtt tttagacggt
    15841 gatgttttga cgaaatcttt atccagttca gatgctgaaa agaacgtgat cgatccagat
    15901 aaaattagta gttccttgga agatttttta tctaacaaag acaatatttt attcggtaat
    15961 gattatgtgt acacgaaaaa cttttctcat ttagaagaag aaccactaga aatccaagca
    16021 agccaagagt atgaaggcat cccattcaat gatgatacag caaaaatcgt tctttcttta
    16081 gaaaaaaacg ataatgatta tagcatcacg aaatacatgc agacgcattt atctgatatc
    16141 gagcagctgc gcgaaaagac ggaactgtat acggaagagg aagcaatcaa tacattgtac
    16201 atcaataaca aaataccaag aggatcaaaa attttatggc gtcagctagc ttattcctgt
    16261 attctgaaag tccgggaaaa aaatgtgtat gttcctgttt ggcatgtagc gatcgaaaca
    16321 agcgataaag tggtccaaat tgagagcgtc aacgctttca gcaatacgat cgtgacaaac
    16381 aatactgtac caaaagtgga agatcaataa aaaagcgagt ataatgaaaa aagtttacaa
    16441 agtaagaagg gaagtaggag tcaaatggct gaagaaaaac cagcttttaa aatcagtatc
    16501 ctagcaagtg gaagttcggg taattcactt tatatcgaaa gtgaaaaaaa acggcttttg
    16561 gtcgatgcag gacttagcgg taaaaaaatc acttccttga tggctcaaat tgatcggaca
    16621 ccggaccaat tagatggaat acttgtgacg catgaacatc gagatcatat acatggcgtg
    16681 ggtgtcttgg ctcgtaagta tcatttggat gtttttgcca atcagcagac ttgggaagcg
    16741 atggaaccac tgattggaaa tgtaccagtg gaacaaaaac atctatttga gatggggaaa
    16801 gtcagaacat tcggcgatat cgatattgag agtttcggcg tctcccatga cgcagcggct
    16861 ccgcaatttt atcgtttcca taaagaaaat cggtcattcg tcatgttgac ggacaccgga
    16921 tattgcagtg attatatgcg aggtgtcatt gaaaatgccg atggttattt gatggaaagt
    16981 aatcatgatc ttgagatgtt acgcatggga ccttatccgt ggaatttaaa acagcgtatt
    17041 ttaggagata gaggacatct ttccaacgaa gacggtgcac ttgtcatgac tgatgtgatc
    17101 ggtaatcgga ccaaacgaat ctatcttggc catcttagca aggaaaacaa tatgaaagaa
    17161 cttgctcatt taacaatgga aaatgttttg aaagaaaaag attttggcgt tggacatgat
    17221 tttgaaatct atgatacaga tccagatgaa gcaactgagc tattttcgat ttaaacagtt
    17281 caatcaataa aaatataaaa agcagaagat aaaatcaatc agggttggtt ttatcttcta
    17341 tttttatttt tttagcatat taaaaaaata accgtattat cgactgacta cactgatgtg
    17401 ctgcttttca tgtttctcat ccagtatctc atctactaat gcaatcgcgt aatctgccat
    17461 gctgatcgta ctgtcgctag cagcgtttct ttgtaaataa tcatcactta acaaataagt
    17521 acctgtacgt ttgccatgtg gatcaaataa agaagctgga ctgatataag tccaatgtag
    17581 atttttagat tgtttcaatt ttaacaatcc ttcgtacata ttgaaagctg ttggatagaa
    17641 gggtgcattt ttaggtactt ggtcaatcat acgagtcgtc ttttctgtat ctaagaataa
    17701 cgaagaggca cccccaacga caattaagcg tgtatcggtt ccttcaagca tctcaatcaa
    17761 atgggacaaa gaagtttgat gcatttcttc ttttcctttg ggagcgttga aagcatcaac
    17821 gacaacatca aaagatgcaa gatcagtagt tgtcaactca aataaatcct tttgtataaa
    17881 cggaacatct gatggcaatt tttctggatg acgcacgatt gccgtcacgt ctaaatctct
    17941 ggacaatgct tcgtctaaaa taaatgaacc tgcatggcca gtagctccaa tgagtgcaat
    18001 tttcataaaa aacctccttt tttattcctg tccattgtaa gcagttgctg aatattcgtc
    18061 aaagaatccg atttttgaaa agctcagtgc gcattccttt catggttcgt gatcattggg
    18121 tatagttaaa ttaagaaaac tgattgataa aaatagaagt tgaaggagat aagaaatgaa
    18181 agagtggtta gatcgtgcct ttttaccaat gataacatct gttgtgaatc ttagaccctt
    18241 aactgctttg cgtaatggaa tgacttacac gatcccaata attattgttg gctcgctgtt
    18301 tttcttattt gctcattttc ctgtggatta catcgctcag tggatagaca aaacaggatt
    18361 ttctatgtat tttacacaag tataccaggc tacatttgat gtgatagcct tttggatcgt
    18421 ttttgccatt gcatacgctt atgcaaaaga agaagacatc gatcgcttac cagtcggcat
    18481 aacagccttg tctgcttatc tactgcttat tcagccacta aatactcaga tagatactgt
    18541 ctggacaggt gctgaaggga tactaggagc agttacaact gggctcatca tcggatgggg
    18601 ctatgcacgt ttagtaagac ttgcgaaagg gtggaagcaa agagagaaga tacctgaaaa
    18661 tgtttggcag tcttttactt cattgattcc aatcattgtt atagtcactt ttacgcttat
    18721 cggttcagcg gtttttcaac atttgttcag aatgactgtt gttcaaggag tatggacata
    18781 tgtccagctt cccattcaat cgttcataga cacgttgttt ggtgtgcttt tattaggttt
    18841 ttttgttccg tttttatggt tatttggtct tcatggatct gcgatggtca atgggttggt
    18901 tagtcccgtc ttgcaagcga attcattagc aaatgcagaa atcttagcct caggacaaga
    18961 gttgacggtg gcaaatggcg gacatatcgt tactcagcaa tttctcgatc agttcatgac
    19021 ggttacgggt gctggattga cgttaggggc tgtatttttt atgacggttt ttgcgaaatc
    19081 gaagaaatac agagaattag gaaatcttgc tcttttacca gcctttttca acatcaatga
    19141 atcaattatt ttttccacac cgatcgtgat gaacccgatg atggctgttc cttttatttt
    19201 cgcaccggtc gtttcaggat tgattaccta ttccgcttta tattttggat tcgttccttt
    19261 atttacagca gtccaagtcc cttggacaac accgccgatc ctctcgggtt tcttagtagg
    19321 cggagtgcct gcagcgattt tacaaggtat cgtgttgtca attagttttt tcatttattt
    19381 cccatttttg aaaaaaatag attctgcaaa ctgcaaaaag gaaagacaga caaaaaatga
    19441 tggagcagca gaaaagatga acgactaaaa aacaaaaata ctcctgtcgc tttagattgg
    19501 gaaaatcacc aatctaggat gacaggagta tttatagtca tgtttatact agcccttttt
    19561 ggacagctaa ttgaacaaga acaactaatg tgttcattcc tacgtgtgtg atcatcgatg
    19621 tccagatccg accagttgct ttgtactcta ggctgaagaa gaaacctagg aaaaagtaga
    19681 ttagcagatg accatcatta tgagcaaacg caaacagcaa agagctgatc actgctccga
    19741 cccaaaaatt tgaatatcga ctgatgatcc ccagtatact gcggcggaat acgaactctt
    19801 ccatgatggg tccagcaaca gttgtcgcca aaataaaagc gggtgcttcc atgatcatct
    19861 ggatgatatt ttgtgtattc tcggaagggg ttgctttgcc aaacaataca gattctaaca
    19921 tgacagcgat gctttgcaga atcaatgcga caaagattcc aaccaatcca taaataacaa
    19981 tctttggagc agaagctttt tttaccgctg attcgatcgc taagggttca cgttgcttaa
    20041 aataaaaaat agctaggaca acggcgccta gtatatacat gactgcagtt gctgtgatca
    20101 attcagacgt agattttaca agtcctatcg aagctaggat caagggtgag ataaaaatta
    20161 gaccatagca aaaaatgctg aggaagctat atttttttaa agacatgtaa ttcctccttt
    20221 taagggataa caagcatgca aggcaagctt atatcgattg atttcaatta tatcataatt
    20281 tcaataagca gctgtcagaa taaaatttct tttctttgat ttaaaagctt gcaaaaaaga
    20341 gggagaatga gtattattaa aaatgtaggt tagcactcga aggttaagag tgctaacaga
    20401 ttaaaaaaag agttatcgga gggatttatc gtgttaaaac cattaggtga tcgcgtcatt
    20461 atcgaagtcg caaaagaaga agaaaaaact gtcggaggaa tcgttttagc ttctgctgct
    20521 aaagagaaac cccaaactgg gacagttgtt gcagtcggtg aaggccgttt gttagaaaac
    20581 ggtgaaaaag ttcctgccgc tgtaaaagca ggcgaccaag ttatgttcga aaaatacgcc
    20641 ggtacagaag taaaatacga aggaaaagaa tatctgatcg tcgcaggaaa agatatcatg
    20701 gcgattgttg agtaaatttg gaagataaaa aaataatcaa aaataatcaa tgaggtgaat
    20761 caatcatggc aaaagaattg aaatttgcag aagacgcacg cgcagctatg ttacgcgggg
    20821 tagataaatt agcagataca gtgaaagtaa cattaggacc taaaggccga aatgtcgtac
    20881 tagaaaaatc ttacggctct ccattgatca caaatgatgg tgtgacgatc gcaaaagaaa
    20941 tcgaattaga agatcatttt gaaaacatgg gtgcaaaact tgtatcagaa gtagcatcaa
    21001 aaacaaatga tattgcagga gacggtacaa cgacagcaac tgttctgaca caagcaatcg
    21061 ttcgcgaagg tttaaaaaac gtaactgcag gtgctaatcc tctaggcatt cgtcgcggga
    21121 tcgaattggc aacaaaagca gcagtcgaag aattgcataa tatctcaact gttgttgatt
    21181 caaaagaagc cattgcacaa gtagcagctg tttcttcggg ttctgataaa gttggacatt
    21241 tgattgctga tgcaatggaa aaagttggaa acgacggtgt catcacaatc gaagaatcaa
    21301 aagggatcga aacagaacta gatgttgtag aaggtatgca gtttgatcgt ggttacttat
    21361 cacaatatat ggtaacagat aacgacaaaa tggaagctgt tctagaaaac ccatatatct
    21421 tgatcacaga caaaaaaatc tctaacatcc aagatattct gccattgtta gaacaaatct
    21481 tgcaacaatc acgtccattg ttgattattg ctgacgatgt agatggtgaa gcattgccaa
    21541 ctcttgtatt gaacaaaatc cgtggaacat tcaacgtagt agctgtaaaa gctcctggtt
    21601 tcggcgatcg tcgtaaagca atgcttgaag atatcgctat tttgacaggt ggtacagtaa
    21661 ttactgacga tctaggttta gaattgaaag atgcaacaat cgaaaactta ggaaatgctt
    21721 ctaaagttgt tgtagataaa gacaatacaa cgatcgtaga aggttctgga gaaaaagaag
    21781 caatcgaagc tcgtgtgcaa ttgatcaaaa accaaattgc tgaaacaact tctgattttg
    21841 accgcgaaaa attacaagaa cgcttagcta aattagcagg tggtgtagct gttgttaaag
    21901 ttggtgcagc tactgaaaca gaattgaaag aattaaaatt acgcattgaa gatgcattga
    21961 atgctacacg tgccgcagta gaagaaggaa tggtctcagg tggtggtaca gctctagtga
    22021 acgttatcag caaagtttct gctgtagaag cagaaggaga cgtggcaaca ggtatcaaga
    22081 tcgttgttcg tgctttagaa gaaccaattc gtcaaatcgc tgaaaacgct ggttatgaag
    22141 gatcagtgat tgttgataaa ttgaagaacg tggaactagg cactggtttc aatgctgcta
    22201 ctggagaatg ggtaaacatg gttgaagcag gtatcgtaga cccaactaaa gtaacacgtt
    22261 ctgccttgca aaatgccgct tccgtttctg ccttgttatt aacgacagaa gcagtcgttg
    22321 cagataaacc agaaccagca gcgccagcag ctcctgcaat ggatccatca atgatgggcg
    22381 gtatgatgta agaaaaagca acttgcttat ctacaactga tcattagtga aagacagata
    22441 aaaagaggct ggaacagaag cgtttaactc caagaaataa gaagaaattc acggaaattg
    22501 cttttcaaat ttttgtgaat ttcagcttat t
//
LOCUS       DAXLPY010000044        22191 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.044, whole genome shotgun sequence.
ACCESSION   DAXLPY010000044 DAXLPY010000000
VERSION     DAXLPY010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.044"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            364..918
                     /locus_tag="ACF3UF_001785"
     CDS             364..918
                     /locus_tag="ACF3UF_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3671894.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(1091..1528)
                     /locus_tag="ACF3UF_001786"
     CDS             complement(1091..1528)
                     /locus_tag="ACF3UF_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3671895.1"
                     /translation="MFSSEENKPLYLDYVNHNLKIIIKENNLKHITLHGFRHTHCSLL
                     FESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFMSSTEEKQGSLQK
                     VKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1576..2523
                     /locus_tag="ACF3UF_001787"
                     /pseudo
     CDS             1576..2523
                     /locus_tag="ACF3UF_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
     gene            2794..3229
                     /locus_tag="ACF3UF_001788"
                     /pseudo
     CDS             2794..3229
                     /locus_tag="ACF3UF_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345965.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
     gene            3245..4078
                     /locus_tag="ACF3UF_001789"
     CDS             3245..4078
                     /locus_tag="ACF3UF_001789"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3671896.1"
                     /translation="MLYFSAIDNADFVFSDPFTAEVLSGIEEQAKNHGYFVLVHNVNS
                     AEDVKTIQRNWRFEGFIVVGVRVKEFLELNNVFDGPVVYIDTHLSKETLRELEQQMNR
                     LFVNTNDYQASTLAVEHLIHYGHEKIAFLSFDYIVGEPSVIQERHQAYIDTLKKYHLT
                     FKSHWIYNNSEFERIYQELAEFTAIVVTGDYLAAKLVKFLKNKNKRVMEQLSIIGFDD
                     ITFAELMDPALTTIRLNPGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKI
                     K"
     gene            4323..5348
                     /locus_tag="ACF3UF_001790"
     CDS             4323..5348
                     /locus_tag="ACF3UF_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3671897.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5486..5611
                     /locus_tag="ACF3UF_001791"
     CDS             5486..5611
                     /locus_tag="ACF3UF_001791"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671898.1"
                     /translation="MKHFKKIALTGIAVLTGTLLAACGGGDSNSKDGQVTLSYAS"
     gene            5636..6751
                     /locus_tag="ACF3UF_001792"
                     /pseudo
     CDS             5636..6751
                     /locus_tag="ACF3UF_001792"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            6834..7730
                     /locus_tag="ACF3UF_001793"
                     /pseudo
     CDS             6834..7730
                     /locus_tag="ACF3UF_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            7746..8570
                     /locus_tag="ACF3UF_001794"
     CDS             7746..8570
                     /locus_tag="ACF3UF_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671899.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8602..9912
                     /locus_tag="ACF3UF_001795"
     CDS             8602..9912
                     /locus_tag="ACF3UF_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HFD3671900.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            10060..11319
                     /locus_tag="ACF3UF_001796"
     CDS             10060..11319
                     /locus_tag="ACF3UF_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3671901.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11329..12201
                     /locus_tag="ACF3UF_001797"
     CDS             11329..12201
                     /locus_tag="ACF3UF_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671902.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            12213..13043
                     /locus_tag="ACF3UF_001798"
     CDS             12213..13043
                     /locus_tag="ACF3UF_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671903.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            13083..15266
                     /locus_tag="ACF3UF_001799"
     CDS             13083..15266
                     /locus_tag="ACF3UF_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFD3671904.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15327..16547
                     /locus_tag="ACF3UF_001800"
     CDS             15327..16547
                     /locus_tag="ACF3UF_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFD3671905.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16544..18004
                     /gene="gtfA"
                     /locus_tag="ACF3UF_001801"
     CDS             16544..18004
                     /gene="gtfA"
                     /locus_tag="ACF3UF_001801"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HFD3671906.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            18081..19187
                     /locus_tag="ACF3UF_001802"
                     /pseudo
     CDS             18081..19187
                     /locus_tag="ACF3UF_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19509..19718
                     /locus_tag="ACF3UF_001803"
     CDS             19509..19718
                     /locus_tag="ACF3UF_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFD3671907.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19711..19860
                     /locus_tag="ACF3UF_001804"
     CDS             19711..19860
                     /locus_tag="ACF3UF_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFD3671908.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            20014..20679
                     /locus_tag="ACF3UF_001805"
     CDS             20014..20679
                     /locus_tag="ACF3UF_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3671909.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(20963..22048)
                     /gene="xerS"
                     /locus_tag="ACF3UF_001806"
     CDS             complement(20963..22048)
                     /gene="xerS"
                     /locus_tag="ACF3UF_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFD3671910.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT         7551 a         3331 c         4253 g         7056 t
ORIGIN      
        1 aaaagtttgg tagcacggtt attcatatgc taatttattt cactttatag taaggggagt
       61 tcttagtata ttgttcaaac ttaaatttca tataatttaa ttatgtaaat tagctattct
      121 aagaacttct acggataact gcccgtctaa aatttaaata agagcttaga atcttcatat
      181 aagtaaggtt aatttttttg tacaaaaaag tcggaatatt ctgagttact gaaatgatat
      241 aaaatcataa actaaatccc ttgattttat tgactttcaa aagtttatat atataagtta
      301 atgattatgg taaaatatat acataatcat taactcagaa tatttttaag aagggaaaca
      361 atagtgagct ataatgtaca accgttaagg acaaatgaag agatacaaga ttttcagttt
      421 tggctaagaa gaacaagtaa tccggaaaga gatagttttt tatttttgtt tggaatcaat
      481 aatgggttac gtatgtcaga tattatagga ttaaaagttg gagatatacg aggcaaaagt
      541 aagcctatta ttgttgaaca taaaacaggt aagcgaaaac cgatttttat agataatttg
      601 agagaagaaa ttttattata tactgaaggt aaagaagaaa atgattggtt atttccgagt
      661 cggcaacaag gtcgacatat aacaagggat cgtgtctatc agatatatgc agatatagca
      721 gaaaaattag gacgagatga tataggaaca catacattaa gaaaaacttt tgggtatcac
      781 tactacaaga aaactagaga cattgctacc ttaatgttta tttttaatca tagctcgcaa
      841 gcaattacaa aaaggtacat tggtataact gaagatgaaa taggagcatc acttcgtgga
      901 tttaaactag gtgtataatt taaaaatttt tataaacagt aaagacaaag attaaaagct
      961 atttttatct agaacgattt tatttcataa agttcgcgga ataaaagctg gggttactgg
     1021 tacttggtat aggttcgtgt tatataaact aagtaattaa ataacatttt taggttggaa
     1081 aaggatgaaa ttaaaaaaag agaatcaata cggtctcaaa aacgcaaacg ctgcggaata
     1141 agaaaaatac tgataactca acgtttagca gactatctaa tagggatagt ctgctttttt
     1201 cgtttttgac catacttttg accttctgca aacttccttg cttttcctct gtagaactca
     1261 tgaaatctgc aaaacgaatt gccgtttcct ctgtctgctt tttcgcgata tgggtgtata
     1321 tatcatccat agtggtttta atatctgtat gtccaagtcg aacatacact tctttgacag
     1381 acgcaccaga ttcaaagagc agactacaat gggtatgacg aaaaccatga agtgtgatat
     1441 gttttaagtt attctcttta atgatgattt tcaaattgtg atttacatag tctaaataaa
     1501 ggggcttatt ttcttctgat gaaaacaaaa gttgttcacc atcttttata ggtttgattc
     1561 tcatttttag atattatgcc cgcacgtatt catcacattt ctattgtgaa tcgctttatt
     1621 cgaccgacat ttgactttta tcataatata ctcggtttaa aattactaat gaaaacaatt
     1681 aatcaagacg atcataccat gtatcacctg tttttttcag ataatcacca ccgtgtggga
     1741 actgaactga ctttttttga agtacaagaa gggaacaacc agttttttgg aaccaatacg
     1801 attgaacgaa cgatactaaa agttccttcc gaagcatcat tgcatttttg ggaaatatat
     1861 tttgaaacac aaggcgtttg ccattatgga atcgaatcat tttctggacg acctatctta
     1921 cgttttgaag ggccagatgc aacacgatta gctttagttc ccttacgcga atttgaagat
     1981 attgatgatt atttcccgta tgtcacagac cagatcccta cagagcatgc cattttagga
     2041 attgatgcca ttcaactacg cgtacaatat tccgatgcga ctgaacgaga gttattgtcg
     2101 gtaggctggt agcacaaaga atacgtcagt ttcttttcgg gtcatcaacg agtgacaatc
     2161 ttagaaaatc aagacactca gttctatcaa gaagttcaga ttattcaaga tcgtgagaat
     2221 ccagttgcca ttgaagggat tggtagcgtc catcatgttg cgtttggcgt agaaaataaa
     2281 tctgatttac aacgcatcga caaacaatta caagagcgca attttataaa ttcaggaata
     2341 aaagatcgtg aattttttgt atcactttat tatcgtgacc caaatcaatt attgattgaa
     2401 attgctacag gggaaggaaa cctagatgca aaagcgtatg aaaatcaaag tccacgcttt
     2461 gaagaaattc ctttattttt accgcagtac ttaaatttca ttcgtgaaca agtggagcaa
     2521 taattagcta atcaaatcca tgacgaagag taagaggttg actcataagt caaaaaataa
     2581 agaaaaacgc atcaaatcca ttctaaagaa tgttgatttg atgcggttcc tatttttata
     2641 aactatcatt ttcgactaat aaaactactt atgagtcagc ctctcttttt ttcttgattt
     2701 ttatacctct ttctaggtaa actaaacatc tgccaaaaat accgtgtctc attgaaacat
     2761 tctcaactat ttcaaaataa aggggagtac caaatgaacg agtatattga aattatccac
     2821 gcaagagaaa caacttaaaa atgtcagtct caaaattccc aaaaataaaa ttagtatttt
     2881 taccagcgta tctggttcag gaaaatcatc gattgttttt gatactatta cccaagaagc
     2941 tggtcgtcaa ctgaatgaca cctatgatag ttttacccgt ttatttttac ctaaatacag
     3001 tcgtccagag gttgatgaga ttgataatct ttctacggcg attgtggtca atcaaaagaa
     3061 gattggtggc agtgcgcgct caacgttagg gacgattact aacatcaatg cgttatttcg
     3121 tgtgttgttt tcatgttttg caacacctag tttaggatat gcaaatgctt attcatttaa
     3181 tgatcctagt ggaatgtgtt ctgtctgtca gggaatcggt aagacgattg catttttaat
     3241 aggattgctt tatttttcgg ctattgataa tgctgatttt gtattttctg atccatttac
     3301 cgcagaagtt ttgtctggaa ttgaggaaca ggcaaagaat catggttatt ttgtattggt
     3361 gcataatgtt aattcagcag aagatgttaa aactattcag agaaattggc gttttgaggg
     3421 gttcattgtt gttggtgtac gtgtaaaaga atttttggaa ttaaataacg tttttgatgg
     3481 tcctgttgtt tatattgata cgcatctttc aaaagagaca ttaagagaac ttgaacaaca
     3541 aatgaatcgt ttatttgtaa atacaaatga ttaccaagct agtacattgg cagtggaaca
     3601 tttgattcat tatggtcatg agaaaatagc gtttctttct tttgactaca ttgtaggtga
     3661 accaagtgtt attcaagaac gacatcaagc ttatatcgat acattaaaga aatatcattt
     3721 aacctttaaa tcgcattgga tatataacaa ctctgaattt gagcgaattt atcaagaatt
     3781 agctgaattt actgcaattg ttgttactgg agattattta gcggctaaat tagtaaaatt
     3841 tttaaaaaat aagaataaac gagtgatgga acaattatcg attattggat ttgatgatat
     3901 tacttttgca gaattaatgg atcctgcgtt gacaacaata cgactaaatc caggtaacaa
     3961 gggggcgatt gcttttcacc aactgattgg actggccaaa caagaagaaa taaaaaatca
     4021 agtactacta ttagagggag aattgatttc tcgagactct gttcacaaaa tcaaataaaa
     4081 aagctctgtg aaataagtat agttaacaat aaaatatccg aacgatagag agaatgaact
     4141 gtgatctagc agttcctcgt cgcaaattca ctagaattag cattatttac tctaaattgt
     4201 tcggatattt tttcttgttt ttaattatga ttacagtgcc tatttttaac gaaatttgct
     4261 tattttcaaa atgtatgatt atatgttagt aaacactttc aaatatgaaa agaggagcta
     4321 ttatggtagg aattagggat gttgcaaaac gggcgggtgt gtccattgca acagtatcgc
     4381 gcgtgctaaa tgaggatccg acactttcag taaccgatga aaccaaacga aagattgcag
     4441 aatcggttaa tttttatcat tatgtcaaaa aaagtcccgt tgcaaaaaat ttaacaaata
     4501 ttgcattaat aacgacagtt tctgaagtag atgagttgga agatccctat tttcgaacga
     4561 ttcgcagagg gattcaagtc gaagcagaac aaagcaaagt caatttgaag aaaattattc
     4621 gtttgtcaga aacaccgttg gagcaagacg atttgctaaa atgtcaaggt gtgttgatta
     4681 ttgggcaggt gctatcttct gtgattgaag aagtatcagc aattaattcg aatgtcgtag
     4741 tgattgatga ccctagtatt gaagctgaag tagatgcagt ttatactgat ttaacaaaag
     4801 caacgaatca gcatttagat cgattgtata aaaaaggaca ccgaaacatt gcgtttatcg
     4861 gaggaggacg tgttcgttta gatagccaag gaaataaaca cgtgtcagat gatgattatc
     4921 gaaaaatagc ctatgagacg tggatgaaac aaaaaggatt agaaaaatat agtcaaattt
     4981 atttagaagg ctggaccaca cttgacggaa tgcaggcagc agatttactt ttgaaaaaac
     5041 atgctaaaga taagttgccg actgctatca tggtaggaaa tgatcctatt gctgtggggg
     5101 tttatcgttc acttcaaaaa aatggtctac atattccaga agatatttcg attgtgagtt
     5161 ttgataatat tgaagttgct gaatttttaa cacctgcatt aaatacggtg aatgtgaata
     5221 cagaagaaat tggaaaacta gcagttcgca tggttaatga acgaataaaa gaagttagaa
     5281 atgtttcgat caaagtgatt gtttctaata atattattgt tagagaaagt gaaaaaaata
     5341 tcgattaaaa aagtaaacat ccaaaaaagg gtgtttactt ttttgtttac taatattttt
     5401 agtaaaaaat ctcgacaaaa cattaagtaa acagttatgg tgttgttaac aaaaagaaaa
     5461 cgcattcaaa acaggaggaa ttaagatgaa acatttcaaa aaaatagctt taacagggat
     5521 agctgtttta actgggacat tactcgcagc atgtggtggg ggagatagta attctaaaga
     5581 cgggcaagta actttaagct atgcgagttg agatactgac caagctccag gactaagaaa
     5641 aatgttagat gaatttgaaa aacaaaatcc tgatatcaaa gtagaaatgg agacaacgcc
     5701 ttgggatcaa tattgggtta aattagaagc tgcaacaacg ggaggtaata tgccagatgt
     5761 agtaaccatg cactctagcg aatcctataa atatatgtca cagaatgctt tgatgggact
     5821 tgatgatgtt atcaaagaaa atgatattga catgggaaac tttactgaag gaattgctga
     5881 tttctatacg cttgaagacg aactatacgc aatccctaaa gatgcttctg tagtggggct
     5941 atggtacaac aaagaattat ttgataatgc aggtgtcgat tatccagatg aaacatggac
     6001 atgggaaaca ctcagacaag ctgcaattga tttaacagat gaatcaaaag gcatctatgg
     6061 ttttgcatca catattggaa cagagactgg ctactggcca tttatttatc aaaatggggg
     6121 agaagtattt gccgatgaca atacaaaatc aggtttgaat accccagaag cacaagaagc
     6181 tttagctttt tatcgagata ttgcacttgt tgatcatgct tcaccaacaa ttacagaatt
     6241 acaagatcct gataagttaa gtcgttttca atcaggtaga ttagcaatga tgattgaagg
     6301 aaactggttt gcaccgggat ttttgaaaaa tgactatcta gttgaaaatg ttgcttctgc
     6361 cgtgttacct aagggaaaag ttaatgcaac aattacaaat ggacttggtt gggctgccag
     6421 tgcgagtaca aaatacccag aagaagtgaa aaaactaatg gcatttttag ctagtgagga
     6481 cgccaataaa atccaagcgg aaacgggggc atcaatccca gcactaaaag gctttgaaga
     6541 cgagtgggct gcttcttcag atacaattga tttgagtgct tttggaaaaa tgttggagta
     6601 tggagtccct cgtccataca ataaagatgg attacgagct gaacaagcag aagttcaaat
     6661 tattaaccgt attctgtctg gtgaagtaac tgttgaagat ggaaccgctc aaattgaaaa
     6721 agaagtcaat gcgatattga gcggaaatta aattagttaa ttatacaata tacaggcgaa
     6781 aggattctat ttcgtctgta tattaatgga tgaataccaa aaagggggat attatgaaaa
     6841 atcgaatttt tggaaaatat cgtaaagatc aagtgatatg gggctatatt tttatttttc
     6901 caacggcatt aggattaatt ttattaaata tatggccagc aattcaaaca gcaattttaa
     6961 gttttcaaaa aacggtaggg ttcggtgata ctgaatgggt cggattaaga aattaccaaa
     7021 aaatgtttgc agacggtgaa gtttttcagt ctttattaaa cacattaatt tatgcagtgg
     7081 tttcgatacc tagtattgtt gtattatcct tgttggtggc agttttaatg aatagaaaag
     7141 ttaaaggatt gtcgatttat cggacaattt attttctacc agtcgttgct gcaccatccg
     7201 cagtcgcaat gatttggcgc tggatgttca ataatgatta tggactgatt aataacatgt
     7261 tggctaaaat aggtctcgat ggaccagcat ggttaacgga tccatcgatt gcgatttatt
     7321 ctattatcat tgtaggagtt tggagtgcta ttggttataa catggtgtta ttactagccg
     7381 gcttataaga aattcctaaa gattattatg aagcagcgga aattgatggt gctagtccaa
     7441 tccagcagtt tttcaacatt acgttaccat tagttacacc aacattattt tttgtagttg
     7501 taacaacagt tatcaatgct ttccaagtat ttgatgttat ttttatgatg attactccta
     7561 atagtaccgc catgtttaaa tcacaatcat tagcctattt attctataaa cattcattta
     7621 ttttaaatga caagggatat ggttcggcaa tcgttatgtt ccttttagtg attatattaa
     7681 ttattactgc aattcaaatg aagttgcaga aaaagtgggt aaactattaa ggaggctatc
     7741 aaattatgaa aaataaattt ttttcaaatg cgccaatcca tatcatgctt attttaggtg
     7801 gtattgcaat ggcattacct tttatttgga tgattttaac ttcagggaaa acgttggttg
     7861 aatctaccca aattccacct acaattttcc ctgagaaatt tcagctaagt aactatcaac
     7921 aagtacttga tttattacca ttcatggctt tttatatcaa tacattttta atggttgttg
     7981 gacgagtgat tggctcggtt ttattttcag caatggctgc atatgcttgt gcgcgtctaa
     8041 gttttccagg gaaaaatatc cttttcagct tagtacttat tcaaatgatg attcccggtt
     8101 ccatttttat tactccacag tatttattag cacaaaaatt gggtatttta aatacaattc
     8161 cagcattaat attaccaggg gtagttagtg cgtttggtac gtttttatta agacaatttt
     8221 tcttaggttt acctgatgaa ttggaggaag cggcctattt agaaggtgcc aatatttgga
     8281 cgatcttttt caaaattatg ttgccgcttg ctaaatcagg attggttgca cttggaatat
     8341 tcacagcgtt gtttgcattt aaagatttaa tgtggccatt gattgtcaat acttcaattg
     8401 ataagatgcc tttagctccg ggattagcaa acttacaagg acaatatgcc acgaacttcc
     8461 cacaattaat ggcaggttcg ttattagcaa tttggccaat agttgtgata ttcatcgttt
     8521 tccaaagaaa attcattgaa ggaattgcta caacaggtag taaattataa aactattaat
     8581 tagtgattgg agagtaagta catgacaaaa attacattta ttggtgcagg aagtactatt
     8641 tttgcaaaaa acgtattagg cgatgcgatg ttaactccaa gtctacaaga tgcacatatt
     8701 gcattgtacg atattgatga aaaacgacta aaagaatcaa atttaatgct taaaaatatt
     8761 aataaaaatt cgaatgaaaa tcgtgctgat attgtttctt attatgatcg caaagaagcg
     8821 ttaagagagg ctgattttgt tatcaatgct attcaagtgg gtggttataa accttcaaca
     8881 gtgattgatt ttgatattcc taaaaaatat gggttgcgac aaactattgg tgacaccatg
     8941 gggattggtg ggatttttag aaccctacgg acactaccag taatgttaga ctttgctaaa
     9001 gaaatggaag aagtttgtcc aaatgcttgg ttattgaact atacaaatcc gatggcgatg
     9061 ttaaccatgg gtgttttaaa agcgacgagt attaagactg ttggtttatg tcatagcgtt
     9121 caagtatgcg taccagaatt gtttgagcat ttaggaatag ccgatcaata tgacttaaat
     9181 gactttcaat ggaaaattgc aggcattaat catatggcat tcttgttgga aattacaaaa
     9241 aatggggaag atttctatcc aacaattcgt cagttagctg cagaaaaacc aaatccacat
     9301 ccagattctg tacgttttga attgttgaaa cgttttggtt actatattac agaatcaagt
     9361 gaacacaatg cagaatacca tccatacttt attaaatcaa aatacccaga attgattgac
     9421 gaattaggga ttccgttgga tgaatactta cgtcgttgtg aacaacaaat taatgattgg
     9481 gaaagcatgc gagaggacat tgtaaataat ggggagttaa cacatacgag aagccgtgaa
     9541 tatgcttcat atatcatgga ttctattacg acaggaactc cgtcagtgat tgcaggaaat
     9601 gtcttaaata aaggcttaat cacaaactta ccgacagatg tttgtgtgga agtaccttgt
     9661 ttagtcgata aaaatggcgt gcaaccaacc tatgtcggtg aattgccaac acaattagct
     9721 gctttaaatc ggacgaatat caatgttcaa gaactgacag tagaagccgc tttaacacta
     9781 gataaatcaa aaatttatca agcagcgtat ttagatccac atctatcatc tgaattgtct
     9841 ttaacagata tcaaaaattt agtggatgat ttaatcgaag cacatgggga ctatttacct
     9901 gaatataatt aaaaagaagc tgaaagagta aggaattttc aattccttac tcttttctta
     9961 gttaaattta gtaaaaatat tgacaaaaca cttagtaaac agttacatta gtgttaacaa
    10021 aaagaaaacg cattcaaatt gtataaggag gagcataaaa tgaagtggtc taaaaaaatt
    10081 attttagctt gtatagcact aggagcaacg atctctttga ctgcttgtgg aaaaaatcag
    10141 gaagatgcaa gcggtaaggt agaaatagag ttttttaatc aaaaaaaaga aatgactcaa
    10201 acgattcagg agattgctaa agattttgaa gcaaaaaacc ctgatattca tgtaaaagtt
    10261 gtggatgtac cgaatgctgg tgaagtaatt aaaacacgta tgcttgcagg cgatgtacca
    10321 gatgtcatta atctttatcc tcaaagtata gaattgaaag aatgggcgaa agctggttat
    10381 ttagaggact taaccgaaga accgtattta gagaatatca aaaatggata tgcacaacgt
    10441 tttgctattg aggatcgtgt atatagcata ccattaaccg ctaatgtcta tggtttttac
    10501 tataacaaaa ctgcttttga ggaaatgggg attcaagcac cagaaacttg ggcagaattt
    10561 gaaaaaatag tagctgagat taaagatcaa aacaaagtac cgtttgcgat tgcaggagca
    10621 gaaggctgga ctttaaatgg ttatcaccaa ctagctatag cgactgctgc tggtggtgaa
    10681 gaggaagcga acaatgtttg gcgtttctca gaagttaatg gaattaatgc tgaaagcaaa
    10741 gaaatgcaaa aagattttaa tcgattagat ttgttaagag aaccaaaagc tttgcaaaac
    10801 aactggcaag gtgccggtta taacgataca gtagttactt ttacaaaagg tgatgcgttg
    10861 attatgccga atggttcatg ggcaatgccg atgattcatt cacaaaatcc agattttgaa
    10921 gtaggaactt ttccttttcc agcagatgaa gcaggtcaaa gtctaacgat tggcgcagga
    10981 gacctagcct tatcagtttc tgcaacttct caacataaag aagaagccaa acgttttgta
    11041 gaatatatga caacacctga agcgatgcag aaatattatg atgtagatgg tgcaccgtgt
    11101 gctgttgagg gcgttatcga gaatactcag gattcaccat taagtggttt aactgaactt
    11161 gcttttactg atcgtcattt agtttggtta gccaaagatt ggaatagtga aaatgatttt
    11221 tataccttaa caacaaatta tttacacaat ggcaatcaaa aagccatgat taacgcatta
    11281 aatgctttct ttaatccaat gaaagctgac ggaaggtagg aaaataaaat gaaaataaaa
    11341 gaaattttaa atcgttactg ggcaatcatt tttgtagcaa ttccaattat tttgcagatg
    11401 atttttttct actttccaat ggttcaaggt gctttttaca gtttaactaa ttggactggt
    11461 ctgacttata attttgattt tgtgggtttg aacaattata agattctttt ttctgatccg
    11521 aagtttatca aatcgattgg cttcacttta attgtgacgc tttgcatgat tgctggacaa
    11581 attggttttg gtattttgat tgcgcgggcg ttgaacgcaa atattaaagg gaaaacattc
    11641 tttagagcat ggttcttttt tccagcggtc ttatcgggcg tggttgtttc tttagtattt
    11701 aaacaaattt ttaactatgg tttaccaaaa attggtagta tgttaggcat tgaattttta
    11761 caaaccagtc ttttaggaac aacatgggga gcgatttttg cagtaatttt tgttttactt
    11821 tggcaaggaa ttgccatgcc agtcatcatt ttcttagcgg gttttcaaag tattccacaa
    11881 gaaattattg aagctgctag aatggatggg gcgaatgata agcaaatttt ttggaatatt
    11941 gaaatcacct acttattacc aagtatttca atggtattta ttatggcatt aaaaggtggc
    12001 ttaacagcat ttgatcaaat ttttgcttta actggtggtg gaccaagcga tgccacaaca
    12061 tctttggggt tacttgttta taattatgct tttaaaaaca atcagtttgg ttatgcgaat
    12121 gctattgctt tagtcttatt tatcttaatt gggattgttt cactggcaca attaaaatta
    12181 tcgaaaaaat ttgaaatcta ggaggtttcc caatgaaaac atcaaaagaa aaaaatattt
    12241 ctaaatactt gcttttatta ttagggggct tcatgatttt agttccctta gtttcaacgc
    12301 tattcggttc atttaaaaca acacccgata ttatgaataa tttctttcgt tttcctaatc
    12361 cagcgacttt ggaaaatttc cgaagattgt tagcggatgg aattggtcat tacttttgga
    12421 attcggcaat catcacaatc attgcagtag ttgctgtgac agcaattatt cctatggctg
    12481 cttattcact agcaagaaaa atgactcgtg ggaaagcata cggattgatg tatttatttt
    12541 taattttagg aatttttgtt cctttccaag taattatgat tccgattacc gttatgatga
    12601 gtaaaattgg tttagcaaat atgtggggat taatcttact ctatctcact tatgccgtac
    12661 cacagacact atttttatat gttggtttta ttaaactaaa tgtgcctatc agtctggatg
    12721 aggctgctga aattgatggg gctagtcact ttacaactta tttcaaaatt gttttcccaa
    12781 tgttaaaacc aatgcatgcg acgactatta ttcttaatgc tctatggttt tggaatgatt
    12841 tcatgctacc attattaatt ttaaatcgtg attctaatat gtggacacta ccattgtttc
    12901 aatataatta tacgggacaa tattttaacg actatggtcc aagttttgct tcctatacag
    12961 taggaattgt cacgattaca ctagtttatc ttgctttcca aagaagtatt atagctggaa
    13021 tgagcaatgg agcagtgaaa taaccaataa attattctca ttataaagga gttcataaac
    13081 ttatgattat atttgacaat cacacacaaa catttcattt acaaaataaa aaaattagct
    13141 atctattagg aatcgaagaa aataattatt taacgcatct ttattttgga aaaaagatta
    13201 cgcactattc tggtgggtat cgctaccccc gaacagatcg ttccttctca cccaacaatg
    13261 caaatgcgca agatcgttta ttatctttag acacattacc attagaattt ccaggatatg
    13321 gacatggtga ttttagagaa ccggcgcata atattaaatt aggaaacggt agtcgtgtaa
    13381 atgattttcg ttatgatagc tacgaaattc aaaaaggaaa gcccagctta gcgggattgc
    13441 cagccttata tacggaagat gatgatgaag ctgaaacgct gattattcaa ttgaaagacg
    13501 cgattagtgg attgacttta cagttgttct acacaattta tcaaaatcac agtgtaatta
    13561 ttcgttctac gcaattagta aataatagtg atgaaacagt ggagattaac cgcttagcta
    13621 gtcaatcaat tgattttcca aatcgtccac tcgagttaat tcatttaaat ggtacctggg
    13681 caagagaacg tcaaatgact agagaaaaaa ttcatacagg gataaaagta ttagatagta
    13741 aacgcggatc aagcagccat caacaaaatc cgtttgttgc tttagtagat gccaaaacag
    13801 atgaatttca aggagaggca tatggattta atttagttta tagcggtaat cacgaaacgg
    13861 tgattcaaaa agatccattt gaccaaacac gggtcattat gggaattaat tcatttaatt
    13921 ttggttggca actaaaaact ggcgactcat ttcaaacgcc agaagtcgtg atggtttata
    13981 gtaatgaagg tctgaatacg ttatcacaga cgtatcatga attgtataat caccgtttaa
    14041 ttcgtggaaa ctatcgttta aaagaacgtc ccacgttaat caacaactgg gaagcaacgt
    14101 attttgattt taacgaagaa aaaatcatga atattgtcga tgatgcgaag aacttgggca
    14161 ttgaaatgtt tgttttagat gatggttggt ttggcggtcg tgaaaatgac ttcacttcat
    14221 taggtgattg ggttgaaaca gaaggcaaac ttgcttgtgg tttggaaaat ttagccaagc
    14281 aagtgcatga taacgggatg aaatttggga tttggtttga accggaaatg atttctgaag
    14341 atagtgaact atttcgagca catccagatt gggcattggg tattccaggt cgtgaccgct
    14401 caattagtcg aaatcaatat gttcttgatt tttcaagaca agatgttcgt gataatatct
    14461 atcaacaaat gacggcgatt tttgatcgtg taccgattga ttatgtgaag tgggatatga
    14521 atcgaaatat gacagaagtc tattctgtct tgttggactc aacgatgcaa ggtgaagtgg
    14581 ctcatcgtta tatgttaggg ttatatgaat ttttagaaaa gttaacaacg aattatccaa
    14641 ctattttatt tgaaagttgt tcgggtggag gcggtcgttt tgatgcaggt ttcttgtatt
    14701 acatgccaca aacttggacg agcgacaata ccgatgccgt ggctcgtctg aaaattcaat
    14761 atggaaccag cttagtgtat ccaatttcaa gtatgggtgc gcatgtttca gcagtcccaa
    14821 atcatcaaac aggaagagaa acgagtttaa ctattcgtgg caatgctgcg atggctggtg
    14881 tttttggtta tgagctagat ctaacgcaat taacttctga agaaaaagca gaaattaaag
    14941 aacaagttgc cttttataaa aagcatcgcc aacttttgca atatggaact ttttatcgct
    15001 tggaaagtcc gtttgaaggc aatgatactg catggatgtt tgtctcaaaa gaccaaacag
    15061 aagccatggt cttttatttc cgagtattag cagaagctgc gcatccatta gtcacattga
    15121 aattagcagg attagcagaa gaagcaactt atcaaatgga agatgtaaca tttgctggcg
    15181 atgaattgat gaatctcggt ttttatattg actcagaact acatggtgat tatgcgacac
    15241 aacgctttta tttgaaacag atatagtagc ttgaatttac aatataagtg caacaccaaa
    15301 agagactcat tccaaacgaa gaaaatatgt tttatttaca cgcatttact aaaaagcagc
    15361 ctgatttgaa ttgggaaaat gaagaagtac gtgaagaaat ctatgcaatg attaactatt
    15421 ggttagataa aggactaggc ggatttagaa tcgatgcgat attaaacatc aaaaaaaaac
    15481 tagagtatgg catctttgaa tctgatggag aagatgggtt agccttcatt gggccctgga
    15541 ttcttaatca gtcgggcatt gaagtgtggt taaaagaaat gagagagcgg acatttaaac
    15601 cacataatag tatgacggta gcagaagccg atgttcctaa tgaacgttta gatgaatata
    15661 ttggtgaaga tggctattat tcgatggttt ttgattttag ttatacggat attgatgtac
    15721 ctgaaactgg tgaatggttt aaagatagcc aatggacatg gacggatatg cgtaccaata
    15781 tttttacgaa tcaattagtt acgcaagata aaggttgggg cgccttatat ttagaaaacc
    15841 acgatcaacc acgttcaatt aataaatata ttccagaaga atggatcaat gattatagta
    15901 aaaaaatgtt ggcgacgctt tttatgttac taagaggtac cccttttatt tatcaaggac
    15961 aagaactagg aatgaccaac atagaaatgg catcattaga agattttgat gatgtagcta
    16021 cgcattctca gtataaacgg gcattagaat atggattggc accagagcaa gcattgaaag
    16081 ctgtcaataa acgaagtcgg gataattctc gcacacctat gcaatggaat acgcaaaaaa
    16141 atgccagatt ctcaacttct gataatgtat ggttaaaagt aaatcctaat tatccagaac
    16201 tcaatgcaga agctcagtta accaatcaac agtcggtatt caattattat catcaattaa
    16261 ttaaattaag aaaaaatagt gtatacaaag acgtgctaat ctacggacaa tttctaccag
    16321 tgaaagataa aaatgaacat attttgcttt atgaacgcca attagaagat aaaatcgtat
    16381 tagttatctt aaacgttaca gcaacagaac aagaatatta tgtagatgaa cagtaccaac
    16441 aagtattaat caataattat gaagatgttt tattagatca aagtcgaaaa ttgcgtttac
    16501 gaccgtttga aagtattgta ttagctaatt atggaggaca attatgaaaa ttaaaaacga
    16561 agcaatgctc atcacctatg cagatagttt aggaaaaaac atgggcgaat taaaacaagt
    16621 cttagacaaa catttacaag gtgttattgg tggtgtacat ctgttgcctt tttttccatc
    16681 gacaggtgat cgaggctttg cgccgagtga ttatacgaca gttgatccag ctcttggaac
    16741 atgggaagat gtggaagcat taggtgaaga ttattatttg atgtttgatt ttatgattaa
    16801 tcacatttct cgtgaatcaa aatttttcca agatttcaaa aaaaaccatg agcagtcacc
    16861 atacaaagaa atgtttatcc gtattcatga atttttccca gaaaatcgac caacacaaga
    16921 agatattgat ttaatctaca agcgtaaaga caaagcgccg tttcaaacgg tagaatttgc
    16981 ggatggtacg acagaagagg tttggaatac ctttggggaa gaacaaattg atttagatgt
    17041 gaccaaagaa gttgtgaaag aatttattcg agaaaccatc aaagatatgg cgaaccatgg
    17101 ctgttcttta attcgattag atgcgtttgc ttatgcgatt aaaaaattag ataccaatga
    17161 tttcttcgtg gaaccagata tttgggaact tttagacgaa gtgcgtcaag aagcagcgaa
    17221 atatgacgtc gaattattac cagaaatcca tgagcattat tccattcaaa tgaaaattgc
    17281 caatcatgat tattatatct atgacttcgc cttgccaatg gtcactctgt attcacttta
    17341 tagtggaaaa tcagaacgtt tagccaattg gttgaaaatg agtccgatga agcagtttac
    17401 aacattggat acgcatgatg gaattggtgt tgtggacgct cgtgatttat taacagatga
    17461 agaattggat tacacctctg aggaattgta taaagtcggg gcgaatgtga agaaggtcta
    17521 ttcaagtgcc aattacaata atttagatat ttatcaaatt aacagcacct attatagtgc
    17581 attaggcgat aatgaccgta gctatctgtt agcacgtgcg attcaagtat ttgcgccagg
    17641 gattccacaa atttattacg ttgggttatt agcaggaaaa aatgatattg aactgttgga
    17701 agcaacgaaa gaagggcgta atattaatcg tcattactat gatttagccg aaattgaaga
    17761 agaagtgcaa cggccagtga ttcaacaatt atttgcactt ttaaaattta gaaatgaatc
    17821 tgcggcgttt gatttggatg gaacgattga agtagcaacg ccatcagaat cagaaatagt
    17881 gattacacgt aaaaataaaa acggtagtga tagtgcaaca ttaacggcta acttggatac
    17941 gaaagaattt atcattgagt ctaaagatat aaaaattttc actagtgttg cattaaaatt
    18001 ttaacctatt ccatagaaca aaaaatcctt tatactagca cttggatgac ttatccaaga
    18061 ccaataaaaa ggactcatac atggataagt ataaaacaaa tacagcattt aataaatggt
    18121 tttctgccat aaaattagga aaactttctg tcaactccca aaaatgtatt tttgattaca
    18181 attcgtatcg taaaaaactg tcttttgaag ctgtgctcaa gctctttctc tacgcagtta
    18241 atgaagaaaa agaaagtttg cgtgatttga gtacagctct tatcgaccga tcgctccaac
    18301 tagaaaccga tgtgtcatcg attagtcata cccaattgtc tcgagcattt aatgcacttg
    18361 aacctaaagt gttagaagaa atttttcaac aactgttaga aaaagttcaa catcaaatca
    18421 aaccaaccaa gcgaaatcat ctgtatctga ttgattccag tacgttttcg cttagtttaa
    18481 aacgtcataa gtgggcgact ttccgtcaaa caaaatcagg tgtcaagtta cacttaaact
    18541 attgttatat ggacgatact acgatgtatc caactgattt taccttaaca aatgcccatg
    18601 aacatgatct caatcaacta ccagtattgg tgaatcaacc agaggcaact tacgtgtttg
    18661 atcgtgggta ttaggacttt gaaaagatgg atcagatgca ttgggatggc tatttcttcg
    18721 tcactcggat taaaaaaaac accaaagttc acgtgataga tactctggaa acatcgccag
    18781 aaacagaaat tctacgagac gagctggttc gtttaggatc taaaacctat ctaaccgcca
    18841 atttccgact agtcactgtt caagataaga acggacgtgt gtttcaattt atcaccaatc
    18901 gaatggacgt ctcttcaaaa gaaatctctg atatgtatca cgctcgttgg caaatcgaat
    18961 tgtttttcaa gcacatcaaa caacacatga ccattaaaac cttcttttct caaagtgaaa
    19021 aaggcgtgca gaatcaattg attttaacga tgatttccgc tctcctcacg tttctcatca
    19081 aattggagac gaaaacggaa aaatcagtgt tccaaatcaa acgattcttt cgttatttac
    19141 tgtttcagcc ctttgaatgt tgtctagaaa aattaattcc cacatgagaa aaaagaaatt
    19201 tggctcgtta cttttggttt tcagttgaat aacagataaa aaattttctg gaaaaagtca
    19261 tcctctgcgt cagcacagtt ttttttgact tattttcaga ggaaatagtt ttcagaatat
    19321 tctaaaatgt tttatgcaac actagtgata ttttttagaa ttagatttct aatgtgcatt
    19381 ttttgagtat taaggagcaa gtatacaaag atttataaag ctgattaaat ttgaataaaa
    19441 atatgcagga acgctactat ttttagtagt gttctttttt atatttgaat aaaaaatgtg
    19501 gtggttaaat ggtggttata acaaaaaatg aattaatgaa attaggttat gggaagtatc
    19561 agtctgagag aatcatacga caggcaaaag caattatggt ttcaaaaagc tatacctatt
    19621 acgaaaatag aagattagga ctagtacctg ttgaatctgt agaagaagtt ttaggtatga
    19681 agatagaggt agaggaggat tttcagaatc atggttaatt ttaaaaaaga taaaaatggg
    19741 aaatatcatt ttactgctag tttgggattc gacaaacgaa cagggaaaag agtacaaaaa
    19801 aacgtagagg ggttaaaaca gttaaagaag aaaaaaagcg tataccgaac ttgtttctaa
    19861 ttatggaaaa gaagcagaaa cttctcaaag tactatgttg tttgaggagt ttttttataa
    19921 attattccta ccttattatc aagggaaagt agaagaaaga acatataaaa atcggttatc
    19981 tacaatcaaa aaaacttttc ttatttcttt aaaatggagt taagagaaat acgtccaatt
    20041 gacattcaaa agtggcaaaa taatttattg agcaaatata aaaattctta tgtaagaaac
    20101 atgtatggga tttttcagat gtcattagat cgagcagttg ttttgggact acttgaaaaa
    20161 aatcctgcaa aagttattgg aaatgtgaag aaaaggaaaa ctacagttga tttttggaca
    20221 aaagaagaat ttacaaaagt tatttcaact ttttatattg atgatttgta ccaacatttt
    20281 ggttttattt gtatgtggtt actttttatg accgttatgc gtttgggaga agccactgca
    20341 ttaacttgga aagatattga ttttgaaaat aaaaacttgc gtgtgaataa aacactctat
    20401 tataagagag ccaaaaccta tgagtttgta gaacccgaaa cggcttctag tattcgtaca
    20461 atcgaactag acgacaatac aattaccttt ttaaaagctt ggaaggagcg tcaagtttca
    20521 ataggaggca tgtcgtttgt actttcttat aatggaacac ctactcagaa atatacaatc
    20581 cgtcatatta tgagaagaca tgcaacgatc gttggtgttc atataatccg catacacgga
    20641 ttaaggcata gtcatgcttc tttgcttata tcacaataaa aagatgcact tcgaattaaa
    20701 gaaaggttaa aacatgctga tgtacaaacg actttaggaa cttatggtca tttgtatcta
    20761 aattcattga gagagataac aaatgatccc acagattata tccaaactaa tttttctaaa
    20821 atcaaaccga cacctattta cgataataaa aaataaatga taaacaaaag taggatcaca
    20881 ccaaaagaaa cacactagaa aaactataat acaggctttt ctagcgtgtt gtttcttatt
    20941 tccgcctatt tatacattat actcataaag catttaatgc atcgatcgta gccgcattgt
    21001 ctatatgggt atataaagtt gttgtattgg tacttgaatg tcccaattgt tgggcagtta
    21061 ataccaatga atttgtctgt tggtagagtc tagtagctaa tgtatgacgc agtttgtgag
    21121 ggctgacttg aattctaaag ccttttgaat attttgctac catccgttcg attgcaatac
    21181 cggatatacg cttggcttct ccttggtaaa ttgctagaaa taaagctttt tcgttttctg
    21241 ttactttata tcgttctttc cgaatagcta gataattagc taaatattcc attgcgaatg
    21301 ctgctatatt gacagcatct cttttatttc cttttctagt tactaccaca ttattcttat
    21361 ctaaagatag gtcatctaaa ttaatattta taacctcgga gagtctcaat ccagatccta
    21421 aaatcagtgc attgatcgcc aggtctcttt ctacatctcg ttgataatag atcaaagctc
    21481 gtttactcaa agtattttta tattcattgg caatataatc tagataattt tgtgtatcct
    21541 tatctagaaa taattttttc tcaatggcat tggcacgtgc agctaacgta gttttatctg
    21601 tgatggttgc tacttgatcc ataggattat tgtctaagta tggttttcct agaggattat
    21661 tggaactttt cgaaagatat ttaaatagaa cctttaatgc cgtgatattt ctattgatag
    21721 tagaagtaga tagacctaag ttattattat ctttgagctt agtttttgtt gtctcttttt
    21781 ttacattttc ttttgtgcga cgtttcaaat gagatttgta caagtttagg tcataggcag
    21841 ttaactgtct tatcgaggtg atagaagtat caggaacgat agactcactc agaagccatt
    21901 cataaaagag cttataattt tttagatatt ctaaagtggt tcgaggtgat tgatctttat
    21961 cctcacgatc ttgaacaaaa tcttttatat aatcgggcat atgaagtatg attgtatcta
    22021 ttttttgata tatttctgta tttttcatgt cattcatcct ttcaataagt aggggagaag
    22081 agtatctcta taattggact ataccaatta tagaatgttt tgtcaattgg tatgctctaa
    22141 aatttattaa tttgtttcaa aaaaagcata taaacaggta tacgtttaat a
//
LOCUS       DAXLPY010000045        22030 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.045, whole genome shotgun sequence.
ACCESSION   DAXLPY010000045 DAXLPY010000000
VERSION     DAXLPY010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22030
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.045"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(61..1371)
                     /locus_tag="ACF3UF_001807"
     CDS             complement(61..1371)
                     /locus_tag="ACF3UF_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFD3671911.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1383..2801)
                     /locus_tag="ACF3UF_001808"
     CDS             complement(1383..2801)
                     /locus_tag="ACF3UF_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3671912.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3041..4609)
                     /locus_tag="ACF3UF_001809"
     CDS             complement(3041..4609)
                     /locus_tag="ACF3UF_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFD3671913.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4613..4894)
                     /locus_tag="ACF3UF_001810"
     CDS             complement(4613..4894)
                     /locus_tag="ACF3UF_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFD3671914.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4891..5814)
                     /locus_tag="ACF3UF_001811"
     CDS             complement(4891..5814)
                     /locus_tag="ACF3UF_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFD3671915.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5811..6689)
                     /locus_tag="ACF3UF_001812"
     CDS             complement(5811..6689)
                     /locus_tag="ACF3UF_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFD3671916.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6676..8013)
                     /locus_tag="ACF3UF_001813"
     CDS             complement(6676..8013)
                     /locus_tag="ACF3UF_001813"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFD3671917.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8016..9119)
                     /locus_tag="ACF3UF_001814"
     CDS             complement(8016..9119)
                     /locus_tag="ACF3UF_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3671918.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9193..10701)
                     /locus_tag="ACF3UF_001815"
     CDS             complement(9193..10701)
                     /locus_tag="ACF3UF_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3671919.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10667..11359)
                     /locus_tag="ACF3UF_001816"
     CDS             complement(10667..11359)
                     /locus_tag="ACF3UF_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFD3671920.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11381..12355)
                     /locus_tag="ACF3UF_001817"
     CDS             complement(11381..12355)
                     /locus_tag="ACF3UF_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671921.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12655..13527
                     /locus_tag="ACF3UF_001818"
     CDS             12655..13527
                     /locus_tag="ACF3UF_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671922.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14109..16307)
                     /locus_tag="ACF3UF_001819"
     CDS             complement(14109..16307)
                     /locus_tag="ACF3UF_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3671923.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16539..17531
                     /locus_tag="ACF3UF_001820"
     CDS             16539..17531
                     /locus_tag="ACF3UF_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3671924.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17591..19012
                     /locus_tag="ACF3UF_001821"
                     /pseudo
     CDS             17591..19012
                     /locus_tag="ACF3UF_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
     gene            19005..20504
                     /locus_tag="ACF3UF_001822"
     CDS             19005..20504
                     /locus_tag="ACF3UF_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFD3671925.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20543..21937
                     /gene="uxaC"
                     /locus_tag="ACF3UF_001823"
     CDS             20543..21937
                     /gene="uxaC"
                     /locus_tag="ACF3UF_001823"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFD3671926.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6670 a         4493 c         3823 g         7044 t
ORIGIN      
        1 atcattaaaa aaaataaagg tcaagctaaa atattattta agcttgacct tattataatt
       61 tcaacgattg tcaaaagtat tgtttgcagc tgtgttgcca gtttctatag ataaatcaca
      121 gcttttgaaa cataagtttt gtactgcttc gattcgcccg aattcttttg cagttatttg
      181 gcaatgagaa aagcagacat cttctatagg cttttcagga aatgctacta aatcaaaagc
      241 tcgggaagga agtgagtaac ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc
      301 tttgactttc gtcatttgct ttgattcagg tatttcttca gccactgctt gccaactttc
      361 tggcatttga gcaaggtcat tgctattttt tctattgtat tcattatgcc agtccattat
      421 ccaagaaaaa ggaaattgta catcaatcat attcagattt tctaccctga tattttcgat
      481 cactccccct ctttcttttg aagatttcat tcgaatacca cagtctgact gaaaaaaatt
      541 gatatcgtga atatatacgt cactaactcc agcactaact tcgctaccaa tagttacacc
      601 gtatcctgaa cggattttac atctagcaac ctcgattctt gatgattttc gattgactct
      661 tgcaccattg ccatctctgc cagacttaat agcaatacaa tcatcaccac aggccaaatc
      721 acattcatag acacgcacat ttgttgaaga atcaatatca atcccatctg tacttggtcc
      781 atcattgttg cggatgatta ctttttctac taatacatcg ttagaataag tgatttgcaa
      841 gttccaaaaa cctgatttct gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata
      901 cagtaaacaa gcgcgtggac gtttaatagc ataatccgca atccaacgaa gtcccttttg
      961 atcgtattca gctcttgtcc cgcttttttg atcttttccc caatacagct cccaccaatg
     1021 gtctccttga ccgtcgatta ttccttttcc ttctataaga atatctttcg ccgagagaac
     1081 attcaaaatc gctgctggcc atttcatttc tacgccggct actcgtgtat cgatttctgg
     1141 aaatgcttcg atatctgttc tccccttgag gactgcacct tcttcaaaga taagatgact
     1201 cttatctttt aaaaaaaggg ctccgactaa ataaatgcct tttggaataa atacaggtaa
     1261 gtgttctttc gcaccttgat cgattgcttt ttgcagtatt attgtatcat cttgttgagt
     1321 gtcgtttgtt ttaaagttca aagcattgat aatccctttt tttgtccgca atacgtttct
     1381 ccctatcttt cattgatttt tttcaattct tcaccaataa atacagtttt tgaacgattc
     1441 agtgggtaac ctactagcaa aatgattgcg gatacaaata agcagaatgc tggtaacaag
     1501 tttgccatcg tataaatcct ttcttgtact aaaactgatt ggatggctcc acctgttgta
     1561 gacgattggt aaccaatgag tgccagcata aatccgccta ccgctcctgc acatgcttgt
     1621 cctacttttc tcgcaaaaga atttactcca tatactgttc catcttctct taagcctgtc
     1681 ttatattgat gataatcaat cacgtcagta atgaatgccc agaccatcaa attgaataaa
     1741 ccagatccta aagtagcgat aaataaaaga atcagatata cccatgcatt tgttatatga
     1801 aggaaataca tcagcaagta catacatgaa gaagcaagta acgcaaatac gcttgcttcc
     1861 tttttaccaa ataattttgt cagctttgta gcaaatggtg ctaaaactac tactgttccg
     1921 taagtaaata aaagagcaac agacattgct tgtttattat ggaagtaatc attgaataaa
     1981 taagtcatat tcgtcccagc taaaatctga ttgatcacaa tgaaaatgtc aacaatgact
     2041 aaaataatca gtgctcgatt agctaacaaa ccttttacca actgagaagc agatactttt
     2101 tcgtttttga caactcttac tctttcagta gtcaatttac aagttaacat atatgcgaca
     2161 aatgctattg cagcacatcc gattgaaatc caaaagaaat gattccctga aacgacttgt
     2221 tgtccactct tgttatgggt atacattaaa atcggaatga agaatcctgt agttgatccg
     2281 ccaatcgcag aaccaatgct tcggaacgtg gacaacgagg tgcggtcatt aggatttgag
     2341 ctaattgctg ctgccattgc tccatacggg atattgattg ttgagagaaa aatcccataa
     2401 acaatgtatg aaacaaaaat ataagcaatc ttcaccgtca ttggaagatg ttggacgaat
     2461 ggcaaaaaca aaatgacagt cactaagcaa aatggatact tcatttttct gatccaagga
     2521 ataaatcggc cagtttctgt taactctgag acatcacata atcttccaac catcacatca
     2581 gcaaacgcat ccaaaattct cgaaatcaag aataacgtac ctacgattgc ccctgaaacg
     2641 ccaagaacat tcgtataata aatcatcaag aaactattga ctaaacctaa aataaaacag
     2701 ttacctagat caccgaacat gtagcctatc ttatcggaaa tcccaaattc ctttttttct
     2761 ttttttactg tatttgctgt aacagcattt tgtgaaagca tttgaattcc tcctacctct
     2821 tctagtaaac gttttcaaaa ttataactct ttttttcttg tttttatatt cacaatgttg
     2881 gctttttatt gcattatctt gacagataaa aaacaaaaaa taatctaaaa acattgatgc
     2941 ataagattga taactttttt tacataacaa tatatacaaa caaaaaaatt cactaactag
     3001 tgaaaataag ttagtgaacc tcatttatta aagaattaaa ttacagatga tcttttccat
     3061 catacttgaa aaactcaaaa tcagcataac ttcctctttt tttatttaga tcatgcactg
     3121 ctatcccgat aaaatttcca gtaaaccctc ctgagagtat acacatgttt ttttgcggac
     3181 ctactttctt ccattcttca gttgatacgt ctttcaaatg aaactgtgct gtctctttct
     3241 ttacagtgac tttcaaaaaa gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt
     3301 gtgctactcc gttttctgat tctatcatac gtaggcattt tcccttgtcc tcattccaag
     3361 taacataaca ataaatataa ttggattcat ttaagtacag taccagtcca gccatctgat
     3421 taaaattatt aggcatgtat tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc
     3481 gaatagctaa caaatgatgt tcgaaggtag attgaagaga ttcaccggaa atcagacgta
     3541 aaaaacctgg tctacatttt gtatcacacc aatcagcatt tggcaaaatg cgtctggcat
     3601 tccagttctt ctttagctct ccttcaaatg tatccataaa ctgatgatct ttttcttgtt
     3661 gtacctcttc atttgtctca atcattattt cttccatcgg agttgtctgg ctatctttaa
     3721 gtcttaacca atcgtcggac gtccaataca cttcttgaat agcggtttct cttcccaaaa
     3781 tagccgcacc gtttaatggt ctggtacaaa gatatgtcat gtaccatctt cctgacgggg
     3841 tttgtactaa gctcccatgt cctgtacatt gcaatgtaga agcaggtttg tcactagctg
     3901 tcagcatagg aaaaccagga tcaagctcgt aaggaccagt aatattcttt gctcggcaaa
     3961 ctgtaactga atgtcctctt cctgtaccgc cttctgccgt catcaaataa taatacccgt
     4021 tacgaaaata caaatgtggt gcctccgttt tcgctaattc tgtacctgca aatattttat
     4081 agatgggacc atcaagcttc ttcttctctg catcatattc ttgtaatacg ataccgctgg
     4141 atttattcgg tgtgtccaga cgataatccc atagttcatt gacaagccat ttttttcccg
     4201 tttcaagatc atggaacaaa gaaggatcaa agccgttact atttaaataa attggttcgg
     4261 accaaggacc tgtgatctca gatgcagtga tcaaataatt gtggacatct ttaaacggac
     4321 ggcctgcact tttgacatct gtgtaaacaa gataaaacaa tccatcagca taactgatct
     4381 gtggcgccca tatacttcca tttgtaggat ttccttgcaa agatacttga gtggtcaaaa
     4441 tatccgttgt atgtgaccag ttgactaaat ttttcgactc atatactcgg attcctggaa
     4501 gccattcaaa agaggagaca ataatgtaat accgctcttt cactcttaat atattaggat
     4561 ctggattgaa tcctcttaaa ataggatttt tcactttgat agtctgcatg attcaggctc
     4621 cttttctcat tcttactcga tataaactga atgccccagc tgctaaaaaa gcaagtgaaa
     4681 taaacaacac aacggcaaac agaccagtca tgtcctgtaa taatccaaat gtattttcta
     4741 aagacaaagt tgaatgatct acagcaagcg actgataact ttttttaaac tctgacgcag
     4801 acatattact taaagtaact gctaacccgc caaagaaaat caaagataga ctgccaccga
     4861 ccattcctag caatagttcc cattttcttt tcatttctga accccctgct tttctaaatg
     4921 tatccattca ggtcttttga tcgatgtttc ataattgtta ttacgttcag agaatttgac
     4981 agtctgttca tttttcttgt catcccaatt atcccaacca gttgggtgaa catgcccacc
     5041 tatcttacac gcttcaaata agacatttgc atacggacgc cacggtcttc ctaaatagac
     5101 gtttctagta tcaggttctg cagtcaaggt acagctttca aaacgatacc ctgttttttg
     5161 atttttcggc gtagatgctg ctgtgatgta tccaggattt ttactggcta agctatggat
     5221 atgacactga tgaaaaacgg catctgcccc accaaatatg aaatccaccg ttccttcaat
     5281 ccagcaatat tcataggtct gacgacaata ctcaggattg gcagaagccg gtgtacaaaa
     5341 aggagtacca tctttttgca aatcaggcaa cggacccgtg cataaggtat cctgataacc
     5401 agatagtcga cagtttttta aagatacgcg atctcctgaa ttgaataaag caacagcctg
     5461 tcctaccttt tctcctggac ctgctgtatt ttcgatgtga agattttcta atacgacatt
     5521 cgatccttct aagaaaaaag tagcacttcg gaaagtccct aactggctac cgtcaagata
     5581 ctcctgtttt gcaaaacgat taccggagat aactactgtt cctgctccca caagtttaaa
     5641 attggataat ctgctttcta tatattcatc atatcttcct tcttttacta tcaagacctt
     5701 tggatggcta tccggcaggc ctgccaaata atcgattcct tcttggatag tttcaaaatc
     5761 cgtcggggta tctatagcat tctttccaat tatcagtttg tctttcatcc tcataaatgc
     5821 tcccttatga attgtttcca aatatttctc atttcttgtg tttccatatg accgcctgtt
     5881 aaagaaaaag aagaaaagtt ttctggacta cccattgatt gatacttttt gtccagccct
     5941 tttctcagct tcagtacgcc ttcgtccaag cacatcgtat cgttttttcc aactaagcta
     6001 agacgagggc gcggagcgat tttttcttgg attgctaacg ttgtataagc tgtcaataga
     6061 tttggcacat agtaataaaa cccatgatga tctaggcggc gatgtagcaa aagtgtttcg
     6121 atgtccacct gtgccgctag atcaatacaa actttgacac gagaatccaa tgctgtcacc
     6181 caccagctta ataagcctcc catagaaaga ccaatcgttg cgagccgttg agtatctgtg
     6241 tcttcccttg tctccaaata atcgatcaag ctgatcacat cataaatacg cattccccat
     6301 aacgtttttc ctgttaataa aaattgtttg aacaactcgc tttcagaaat acctccgcgt
     6361 tcttcaaatc cccaagcatc aatcgaccaa acagcatatc ccattcctgt cagtacttct
     6421 gcaaaagatg gagaagctaa gtaaggagca ccatggatca attcactttt cccgactgaa
     6481 aaatctccgc cgtgagaatg caggtaaagg accgtcggaa acggtccttc tttttctgga
     6541 taagcataga gggctggtac tgtttccaat tcatttaagt acaattgata gtattcaagc
     6601 ataaaaccgt tttgtttttc tcggtataat cgttttccac taggggtatg tctgctagat
     6661 ggagcaccta aaaaatcatt caactgcata agcaaagttt ttacgaacaa ccagttcatc
     6721 catattttct gattgatttg attggaattt ctcaatactg atttctttag tattttctaa
     6781 tagaaatgct ggtccctcgt gattttcaat cgacatctgg ttaaaggaaa ccttacccgc
     6841 aaagccaata taaaatcctt gtctgctcat ttcctctatt cctgtcatca tagcaggaac
     6901 accgggaact gcatcttggg ccatcgagac atcgatattg tcaaatgtga tttcttgtat
     6961 gaattgttcc gctaatccat aaataaaacc tgcagaagca tggacattcc ttgccgtgat
     7021 attcgaaaaa tggatccttc tgaatgctga tgtccgttca tctatcggat aagccttttt
     7081 ttcccataca tacggttctt tccctcgcgg accacagaaa taataaagat tcagtataaa
     7141 tggacacatc acattatcca tgactatatt ggatactcga atatcttcaa cgatcccgcc
     7201 tcgacctcgt ctagatttca atcgtattcc tcgatcagtt tcttggaaga tacaatttga
     7261 aatggtaata ttacgaatac taccactcat ttcacttcct aatacgacac cgccatgtcc
     7321 atggaccatc gtgcaatttg tgatcgtgat attttcgcaa gcgatccttt cgtacgtatc
     7381 ttcagtccct gccttgattg caatacagtc atctcccacg tcaatatggc aattactaat
     7441 acgcacattt ttgcatgatt ctggatcaat tccgtctgta tttggtgaat ccgctgggtt
     7501 caagatcgtc aagttatcaa acgttgcatt actgcaaaga atcgggttga tcgtccaact
     7561 tggtgactgg atcaatttaa tatctttcac agtaattcga tgacagttat ggaaactcat
     7621 caatttagga cgaggataag cgagattatc tggttcattt ctaaaagtat gccaccattt
     7681 ttttccattt ccatctaatg taccgaaacc agtgacagag atgttctcta cattttgagc
     7741 atagatacag gaagcataaa cttttcgatg gactccttcc caacgtgaat gaacaacagg
     7801 ataatctttt ggatcgtcag agaatttcag aaccgctcct gcgcttaaat gaagttcgac
     7861 attgcttttt aaaaataaag ctcctgttag aaattcacct gctggaacaa ctacggtccc
     7921 gcctccgtca cttgctgcag catcaatggc ttgttgtatt gcttcagtat tcaattcatc
     7981 aattgatgcg ccaaatgtca aaatatcata catatttata atgcctccac ttcaatcaat
     8041 gcttgcaaga atgcaccaac gcctttttga tcattacaaa taattggttc actgatgtag
     8101 taagcatatg aaccatctcg ctgatctgct ccgcctaacc ctgctacttg acagttttta
     8161 ttcaagttca gccagccttc ttttgtttcc agaacaaatt catcaagtaa tccttgatgt
     8221 gatttcttca cttgtggaag ccattcttct ttgttcagca gtcccaaacg tattccttta
     8281 gccattgcgt aaacaaacat actactgccg gaagcttcca gataatttcc tttccgtttt
     8341 gtttctgttg ttacttgata ccatgtcccg ctgttttctt cttgatatgg aagtaatgca
     8401 gccagtgtct tttctagaat ttctttcagc aaagaacaat ctgtttcttc atgaagtaat
     8461 tcataggtat ctgctgcagc catcaaatac cagccaatcg atcggctcca aaaatgatgg
     8521 gatagacctg tttttggatc agcccatggt tggaccttct tttcatccca tgcatgaatc
     8581 agcaaatttg tttttggatc gaatagatgt ttataactga tttcaaactg tctcaaaaca
     8641 tcttggtaat ctttttcttc actaaaattc tggataaatt cagcataaaa aggagaaccc
     8701 atatataagc catccaacca aatttgataa ggataaattt ctttatgcca aaaagctcct
     8761 tcggatgtgc gtggatggtt tgccaactgc tgggaaagga gttctgctgc ttttttatat
     8821 ttttcttcgc ctgtttcttt gtacaataaa aagaaaagct ttcctgtatt tacatggtcg
     8881 atattgtatt cttcaacgct gtagccacgg atcgttccat cttcttgcac gaaatagtcg
     8941 atattgtctt ttatgaaatc aaaataaatt ttttcttggg ttcgttccca aagtaattgg
     9001 aaccctttaa gtacgacgcc atagtcataa gaccattttc ctttatacca cttttcttca
     9061 tataagcgag gtgttctttc catgatactt tttgctaatt tctttgacca gttttccatt
     9121 atttgctctc ctttaaaaat taaaatagga tttgggacaa ataccaagaa gtatttgtcc
     9181 caatcgtcta tattactgtg ccgctgcttt gtatgcttcc tcgtactctt gtgtgattcg
     9241 atcgcctcct tgtgctttcc agtcttctac agcttttttg aatccatctt cgtcaagctg
     9301 tcccatgatg tattgcaccg tagcatcaat gacgattttt tcaatttctg atcctacttc
     9361 attgttcgtc ggtgaatcca atggcacaga aggatccatt acagcaaatt cttcattttc
     9421 tttgatcaat tgattagaga attctttttc agggtctgta tctttgaaag agaacgtcac
     9481 ttcactagga cgagagcttg ataacggttg cacctcttgt tgccaaagat ccatatcgat
     9541 aaattcgata gaaccatcat cattcaattc ataatgcgtt ccttcgatac cgccagtcat
     9601 caatttatac acatcttctt ctaaaagatc atcaacaaat tgaagtaatt tcttcaattg
     9661 tgcttcgtct tttacttgag atttgggaaa tgctagcaag ccgccaatac catttccttc
     9721 tgaccaaaca tgataaccgc cgccttcacc atctgagatc ttgtttacag gcactaattc
     9781 catatcatct tgaatacctt gacccatcgt cttcagattc ttgatatcca ccattccagt
     9841 gtagattcca gttcttcctt gtgcaaattg ttcttgctga tcagtctttt gggtaactgc
     9901 aaagtcttgt gccaaatagc cattctcaaa tagatctctt gaaaaattca aagctttcat
     9961 atactcttct gtatcaaatt ctggagtgaa tttgccatta tcgtctacag cccagccatt
    10021 tggtgctcca aaataagaag tgaaaagttt aaagctggta taacgaatat cactaggcgc
    10081 acgatcgcca aaaccaactg tgtcgtccac accatttcca tcaggatcgt tttctgtaaa
    10141 ttgtttagct acttcataaa gctcatccat ggtagttgga acatctagtc ctagattatc
    10201 caaccagtct tttcgaatga ctaagccagc acgagcgtag tctttttgta tcggtacgcc
    10261 gtacaaggca ccgtcgatac tcgcagcttc gattctatct tcagaaattt gacttaaatt
    10321 tttatagtct tttaaatatt ctgatacatc ccagaatacg cctgatttta acgcattgcg
    10381 gacagaagag tttttcaaca tcgcaatttg aagtgtaacg atatctccta gttcatcaga
    10441 agccaatgca gttgttaatc tttcttcttt tgaagcatca ggaatccagt tgaatgtcag
    10501 ttccgtatcg gttttttctt cgatcaagtt cacaatcgtg tctgtaggcg gtgaagcatg
    10561 atgcaaaata tttaaccaag tgattttagc ttttccatct tctgtctctg aagaactgtt
    10621 acttgaactg ctgccgcatg cggcaagtgc tagaattcct gcaaaactaa gacctaattt
    10681 tacgagcgtt gcttttttca taaattttct ccttcactgt tttaataata tttttgtttt
    10741 cttctgtttt ttctgtatat gagttcttcc attccaaatg gcaaaatata gaatttgctg
    10801 tccacgtgac tgcggaaaag aagagactgc caccgataaa ggttaaaaca cctggcattg
    10861 tttggatgat catcagataa atccctacca tacttaatat caacactaat gagtaatgaa
    10921 gatgtgagaa tccgaataaa aatgccattt tcattttgaa aaaatatcct ttccaatcat
    10981 aatgagccat gattgggaaa atatagagtg ctgagagcac atatatgaac gcagcaatat
    11041 acaaagcgat cctaagatac caattgtgta tgaaagaaag atccacaagt aaaacaatcc
    11101 cgatggcgcc atatatccag ctcatcagca aggtttcacg atagttttct ttaaaatatg
    11161 tgaagtacgt tttcgtcaaa ggaaacgttt cttttgagcg cagccatttt ctaatcactg
    11221 caaccatcgc atacgatgca ggaccgaaag taaaaactcc caaacctgcg atgactaaac
    11281 cgccccacag aaaattcaaa taaaccaact gtaaaatacg atttagcctt ccgtttattt
    11341 tatctaatga ctgcagcata tctttccctc tctttctatc ttagtaaacg ccgtcttctc
    11401 ctagcttttt ggcaatctta ttagctaaaa ttaccataaa caatcctacg acccctttaa
    11461 acaatcccat tgctgtactg aaacttaact gtccattctt caatccagct gtataaatat
    11521 aggtgtcgaa aatttctgca acgcttcgat tcaatgaatt caataacaag tacatatgct
    11581 cgaaccctaa gtctaatgtc tgaccgattt ttagaatcag caaggtaatg attactggac
    11641 gaattgccgg caatgtaaca tgccatgttt tgcgtaagcg tcctgctcca tccatttctg
    11701 cagcttcata caactgtgta tcgactgcag ttatcgctga aaggtagatg atcgtagacc
    11761 agcccaactc tttccagatc acttgtccga tatatactgt gcgtgtccat tcaggggatg
    11821 ttagaaaact gattttttca aatcccattg ttgcaaggaa ttcattcaat acccctccgt
    11881 caacattcaa aaatacataa gtaatcgaaa caatgattac ccaagacatg aagtgaggga
    11941 tgtaaatgat cgtttgaatc ccgtttttca atcgtttgtt cgttacttca tttaatagta
    12001 aagacaaaat gattggcatc ggaaaaaaca cgaagatatt taatccgaac aagatcaacg
    12061 tatttcttaa taatgtaaag aatgtcggtt ctgtaaacaa acgaatgaaa tgtttgaaac
    12121 cgacccaagg acttcccatt attcctaaaa atggttgata atcttgaaaa gcaataacga
    12181 gtccccccat aggaagatac ctaaaaatca agaaataaag gactcccggc agaatcatca
    12241 catataaaaa tttattcgtt ttgattcctg caattatttt ttttcgtctt ctgagctttt
    12301 cttctttttt cgatagcgtc agttgaaatg gttcttgttt ctttacactt tccataagcc
    12361 cctccttagt tttgtgaatg tttgctgctt atgacttcat gatagataac tatctgaatt
    12421 acgtatataa tcatttttat cgtaagtaaa aacgcttaca tagcaatgat ttttgtgcta
    12481 tacaaaacga taaagtgtat tttttcacaa ataaactacg catagcaaac cttctatttt
    12541 tttctatctg acacttagca taggaaatga ttatatacgt aatctttcac cgatgataaa
    12601 ttgaacatat agaaacagaa acatttaatt tattttgagg aggagcctat ctatatgaaa
    12661 aagaaagtct ctataggaga aagaagtttt acacttttca acaatacgtt tctaattttg
    12721 ctagctttga tctgtatcgt tcctttttta aatatcatcg ctacatcttt tgcttctaca
    12781 caagaagtcg tcgcgaaaaa gtttatcctt tttcctacta ccttttcttt agacgcgtat
    12841 cgctacattc tttctacgcc gaccattttt agagcacttg ctgtttcgat tggtgttaca
    12901 ggtgtcggaa cgatcgtcag tatgtgtgca acttcactga tggcctacgg tctttccaga
    12961 aagtatttgt ttggtcgagg tttcgtcaac tttcttgttg tattttctat gttgttcagc
    13021 ggggggatga ttccaacgtt cttagttgtt cgttctctag ggctggtcaa ttcttactgg
    13081 gccatgatcc tgcctgtggc tgttaatgca atgaatatga tcattatgag aaactttttc
    13141 caagccttgc cggatagttt ggaagaatca gcaaaaatgg atggttgcac agattttggt
    13201 gtatttttca aaattatgct gccattagct ttaccgtcta ttgctactat ctcgcttttt
    13261 tatgctgtta cttactggaa cacttatatg actgctattt tgtatatcaa cgattcatct
    13321 aaatggccga tacagattct tttacgccaa atcgtcattg tatcaagtgg gatgcaagca
    13381 gaaagtagtg ccgttgatgt gattccacca gcacaaacag ttaaaatggc tgttatcgtt
    13441 attgcaacag tgcctatgct gattgtttat ccttttgttc agaaatattt tgtcaaagga
    13501 gcactcgtag gttctgtcaa agggtgatta tgtactgaac gcaaaatggt agttgtgtca
    13561 gaagtggtca gcttcaagaa ataagaaggc atttacgaaa attgcttctt aaatttttgt
    13621 gaaatttcgg cttatttttc gaagaatcta ctcctggaac accgtgtatc agaggttgtg
    13681 aaagagacgt tcagccttga gcgatgataa aaactctcac aaacattgcg acgagtaacc
    13741 cacaggagca ataagaagcg attttgaaaa atagcttccc atatttcaca aaattatgcc
    13801 ttattgtcga tagcctgtct cttgaacgcc atttattcgt aaaaaagaac tgtgacaaga
    13861 cttttgtcac agttcttttt gcgtgcttag ccttgaaatt taactatcca taaatacaaa
    13921 tactagggtt attctaactt cttttattgc ttgaatcagt ccacaagaaa aacagcctct
    13981 tgattaaacg gcgtttatct tgttgattct gcggcaataa aatcagccag cagcaaaaca
    14041 tgaagtgctg ttttttgctg tcctctttta ttgcttgaat cagatcacaa gaaaaacagc
    14101 ctcttgattc acaaatattt ttttcgatat tctcccggcg taatcgattc cttcttttta
    14161 aagaaacgaa taaaattttg cggatttcga tattgcaatc tttctgcaat ctcttttacg
    14221 gagaggttag tctctttcaa ccattttttt gctacctcta aacgatgatt ttgaacaaaa
    14281 tcaccaaatt tttctcctgt ttccttttta aatacattac ttaaatagtt agggttataa
    14341 tgcaacctat cagcgatcac atctaaagac agatcacgat catattctgt gtagacgata
    14401 tgcataatat tctccgacaa atttttaaat tcatgatcag tgattgcttg agagcattct
    14461 gtgattggca gaactaattg ttctaaaaca agtttttcta gttctttggg atgataattg
    14521 ttcagtgctt ttacataaat ttgtttcatg ttatcaaagt tttttgaatc tactcccaat
    14581 aactgtccta attgaacgag ttcattgatc aagcggaccg aaactacttc ccgactcaaa
    14641 ggatttttat tttgtgcaaa caatgcatca atcaattcat gtactaaatt cttcacttcc
    14701 tgatttccag aacgaatggc ttcaaacaat cgattttgtt cttctatcgg atatctaata
    14761 agtgtttttt catgagcagc aggaacgatt tcctgataaa aaataattga acttggacca
    14821 gtatttacac gataatacag ggcttctttt gcccgatcaa ccgattgctt gctttcattc
    14881 agcgtttcga accggttact gatgcctata ctgatagtta aattcaagta ttcttttaca
    14941 cgtttttgaa tgagtcggca atactccatg acttttttgc ttgcttctgc atcatcttta
    15001 tccattcgat aaatagtggc ttgcatttct tcattcaaaa cgatcggcag cattcgattt
    15061 tcctttggca caatttccgt gatcatgttg ttgatcgcta aaagtagcaa atcacgctcc
    15121 ccaccgtgac tatcttctaa cagatcgatt tgaaccaaag ctgtataata gcagtcattt
    15181 tgagaactat aaccaaattg ctgcaaccgc tgatctagtt ctcgcctttc tactcgattt
    15241 ctaaataaac taagtacaaa tagcgtttcc agctgtggct tttgggtaac taagtgtgca
    15301 cttaacgctt ctttttctcc tatgatccga ctgactgatt gagcgaccaa atctagttct
    15361 ttcccactga atccttttga tttaagattc agacgttcct gtatttgaga aatcggacgg
    15421 gcaaatctgt ccgaaaataa gtaggaaaaa agaccaatga gtcctaccag tgttaaagac
    15481 actgcaacta gcccgattct cagattgcgg atcattgcgc caattgcact agagtcaact
    15541 tctaatctgt aaatccaatt attataatct gatttcagta ctatatacgt tttatctttt
    15601 tctcttatca ctttcagctg attgtaatct agatccacgt ccgttaatac agttggttgc
    15661 tctttatttt ttactgtctg agtagtaaaa aggttgccaa cttcgttttc aatagaaagt
    15721 atgtcttctc cactttcacc aacaacttgt tctattgtat gtttctctat cgtagcaatt
    15781 cccaatgcat atttttcttt ttcaaacatt ggcaaagaaa tcaccatttc gattcctttg
    15841 tttttctttt gccaaaataa attatttttg ttatttatgt acttctgttg atacttttca
    15901 acttcctctt cggtcagttg actcaacgat ccattgatta ctccccattt accagccaaa
    15961 ctgactaaat cataattatt atcatccata acaatcgttt ctataaaatt tagttctttc
    16021 ctgatttcag aataagtgga gtaatctgta tatgtcagcg gatgcttgaa tatgtccgag
    16081 aaatttttgg tcgaaccata cgtagaaaac gaatattcaa tcgttctaat tttccattca
    16141 acgttagttt taacttgcct gagcaaattc tttttgtctg ttaaataact cgattcgatc
    16201 gattcatagg tattctggta aatgaataaa ctaaatccta tgacaagtac ggctcctaat
    16261 aaaaacatcg gtaaaaatat tttataaaat actgtacttt tcttcatttt cttcctctcc
    16321 tccttttaaa ataaaaggct ttcatttttc tgtaaaattg atactcatct aattaaatga
    16381 gcattccccg ctttcaagaa tagcataatt aaaaataaaa atccaagtaa tttttaacgt
    16441 gtgcaatctt ttcatatcaa agatctattg acttatcgta gttatcgtaa tatgatgaat
    16501 gcgttaacaa aaagtgaaaa agtaaggaaa atgatggaat ggtaacgatc aaagatatcg
    16561 ctaaagcagc tggcgtttct catacgacag tttctcgtgc tttgaataac agcagtttaa
    16621 taaaaaatga aacaaaacaa aaaatacgac aactagctaa ggaaatgaat tattcgccaa
    16681 actatagtgc aaaaggttta gtgaatcaaa aaaaatatct aatcggacta tttttctcaa
    16741 gtttgcataa aggaacttca tcaaatttcc tagcagattc cattgcaggc atccattcag
    16801 tattagacac aaattacagt ttatctgttg aaagtatcga tgttgttgat ttaacagaaa
    16861 tcaacctgca acgctacgat ggactgatcg ttatgagtca aagtgatgat gatcagcctt
    16921 tcatcgacta tctcaaagaa aaagaatttc ctttcgttgt tgtcaatcgt cacatcaatg
    16981 atccagcggt tatcaacgtc actgccgatg atgcggccgg tgttatgcag gcagtagatt
    17041 acggtattgg atgcggacat acgaagatcg cttatattgg cggaaagaaa aattttcgtt
    17101 cgacaaaaga acgggaaaaa ggggtattga aaagtctaaa aaaagcgagc atccctgtca
    17161 atctagccta ttttttaaca ggagattaca gcttagaaag cggcctccaa aacatggaat
    17221 acctattatc actttctgac ctgcctactc tggttttttg cggcaacgac gacatagcga
    17281 ttggtgcatt gagagctgta catttagctg gcctccgtgt tccccagaac atttctctga
    17341 tcgggttcga tgattctcca gtcgtctcct atctcaatcc gccgcttacc accgtacgta
    17401 agcctttgaa agaaatgtgt caagaaggaa caaagctttt actagatttg atcgaaggca
    17461 ggacgatcga acaatctaaa attgagctct ccaccttgtt gatccttcgt gagtcgatca
    17521 attacttgta aactacaagt aattttatat aaaaatgtta acgtgtgcat aacacagaaa
    17581 ggaagtttat atgaaaaaac tgacaaaaga attagtgaaa aaaaacgaag cacctgtaaa
    17641 agttctttag tttggtgaag gcaattttat gcgtggattt attgattggc agattcagca
    17701 gctgaataac caacaattgt ttaaaggtaa tgttgcaatc attcaacctt tagaacaagg
    17761 tcttggaaat atgatgaacc agcaagataa tttatatacg gtcattttac aaggactcag
    17821 caatggcgaa atcgttgata cttccgagat tatcaccgta gtagaacaaa tgatcaatcc
    17881 ttatgatgaa tgggatgctt atctatctct agcagaaaat gacgacttgg cctatatcgt
    17941 ctccaataca acagaggcag gaatccaatt cgtggagact gataatttaa cagatactcc
    18001 cccacagagc ttcccgggca aactgacagc ctttttatac cgacgtttca aattaaacaa
    18061 agctggcttt accatcattc cttgcgaact gattgacaga aacggcgaac gtctaaaaga
    18121 aatcatttta cgctacgcag aaaaatggga tttagaacct gcttttgttg agtggttaga
    18181 aaaagaaaat gttttctgtt gtagtttagt tgatcgcatc gtcccaggtt atcctcgcga
    18241 agatgcaggt gttttcaatc aacggcataa ctatgaagat caattgatgg tcaaagcaga
    18301 accattcatg ctttgggtga tcgaagggcc taaagaattg gagaatcaac taccattcaa
    18361 acaggctggc ttgaatgtca tcatcacaga tgatatgact ccttatcgtg aacgtaaggt
    18421 gcatttgctt aatggaccgc atacagcgat ggtccctctt gctttgttgg cggaattgga
    18481 aactgtagaa gaagtaatga aagatccttt attctccgca tatgttgatc agttattcaa
    18541 tctagaattg attcctatgc tttctttacc taaagatgaa ttagccattt atgctgacca
    18601 aatcaaagaa cgtttcttga atccttttgc ccatcacaaa ttagaagcga tttcattaaa
    18661 tagtgtttca aagttcagca cccgtctgct tccagtgttc aagaagtata tcgaagaaca
    18721 aaatcaggta ccaccgttaa tcactgtttc actagctgcg ctacttctta tgtatcgagg
    18781 cgatcaagta aagccacatg atgatgaaaa gacgataagc gaatttactg atgcttggtc
    18841 tgataatgga acagctattc ctcgattatt gcaaaacgct gcgctttggg gagaagattt
    18901 gtctcaaata ccgaatgtga cagatacagt tcaagaaata gctgcaaaga tcgatcaaaa
    18961 aggtgtccgg tcagtattac aagaaatgaa aggaacgatg gtccatgctt gaaaccctgc
    19021 aaccaacaat gaaattaaat cgacgagaca gtgtggtcgt cgcattaacc cctattccaa
    19081 aacaaacaca actgacgatt gatcagcaaa cgatcaccac tcttgaagat atcccgcaag
    19141 gtcataagat tgcattgggt gatttgaaag ctggagacaa cgtgatcaaa tatggctatc
    19201 caatcggtca tgtgacgaca gacgtaactg ccggtcaatg gctgcacact cataatgtaa
    19261 aaaccaatct ttctggtgaa ttggattatc gatatgaaaa agatgtccat ccaagtcatt
    19321 acctttttga gaaccgaaca tttcaaggtt acttgcgaaa aaatggaaaa gtagggattc
    19381 gtaatgattt gtttttagta cctaccgttg ggtgtgtgaa tggcattgct gaactgatcg
    19441 tcaaacagtt caaggaaaaa catccagatc tgggacagtt tgaccatatt acgattttaa
    19501 agcatcctta tggctgttcg cagcttggaa aagatcatca aaatactcga gaaattttag
    19561 cggacgcagt aaatcatccc aatgccggag gagttttagt atttggatta ggttgtgaga
    19621 acaatacagt tcctgaattc aaaaaaattt taggtgaata tgatgaagaa cgagtgaaat
    19681 ttctagtggc tcaagatgtt tacgatgaga tcgaacaagg tgtggctcta ttagaagagc
    19741 ttttaacagc ggcggaaaat gaccagcgca tatcagtccc gctctctaag ttgaatgtcg
    19801 gtttgaaatg cggcggttct gatggtctat cgggaataac tgctaatcct ttacttggtg
    19861 cattttctga ctacttgatt gctcaaggag gcagcacgat cttaacagaa gtgccagaaa
    19921 tgtttggcgc agaacaagta ttgatggcac gagcggaaaa tgaagaagtt tttgactcaa
    19981 tcgttgactt gatcaatgac ttcaaacagt atttcttgtc ttacggggaa ccagtttacg
    20041 aaaacccatc tcctggtaat aaagcaggtg ggatcactac attagaagat aagtctttag
    20101 gctgcacgca aaaatcagga agctctcctg tcgttgatgt gctacaatat ggcgaaaaaa
    20161 tcagaaaacc agggcttagt ttattgcaag ctcccgggaa tgatcttgta gctgcctctg
    20221 ctcttgcttc atccgattgc cagttggtct tgtttaccac aggaagaggg actccgtttg
    20281 gctcatatgt cccaacggtc aaggtatcta cgaatacaac tctttttgaa cgcaaaggtc
    20341 attggatgga ttttaatgca ggcgtcttat tagaacaacc aatggaagta atcttagaat
    20401 cgtttgttca aaaaatcatc gctgtagcta gtggagaaga aacgaaaaat gaacaaaatg
    20461 acgttcgaga aattgccatt tttaaaaacg gagtaacact ttgattttca taaaacagta
    20521 taaaaagaaa gaaggaagat ttatgttttt atctgatgat tttttattaa aagacgattg
    20581 ggcgaaaaag ctttaccatt cctacgcaaa aaacatgccc attattgatt atcactgtca
    20641 cttagatcca aaagaaattt acgaaaacaa caatttcagc aatctgacag aagcttggtt
    20701 aggaggcgat cattacaaat ggcgcttgat gcgagcttgc ggcgtgcctg aagaaaaaat
    20761 cacaggaaat gcttctgatt ttgaaaaatt tttagcttgg tgtcaaaccg taccaaaaat
    20821 tatcggaaat ccgctttaca gttggtcaca tcttgaattg aagcgtttct tcggtattga
    20881 cttgttgata aatgaagaaa atgcagagaa aatttggaca caagcaaatg aaattttggc
    20941 agctcctgat tttcgccgtc gggaaatcgc aaaaaaatcg aatgtagaag tgatttgtac
    21001 aacagatgat cccgcagacg acttgcacta tcatcagttg cttgctcatg aagaaccaga
    21061 tttgaaggtt ctaccttcat tccgtccaga taaagcactc aatattgaaa aagaaggatt
    21121 taatgcatgg gtcacactac tggaagaagc agctgaccaa acgatcacca cctatcaaga
    21181 actgatagaa gtcttagggc agcggataga atacttccat caacatggat gtcgtgtttc
    21241 cgaccacgct ttagacatct tacgctataa agaagcggat gaaacagtat tagaagagat
    21301 ttttcaaaaa gcacgagcta acaaactatt atcttcagat gaaatcgatg cttatcttac
    21361 agaaacactg atacatttga cccacttcta tcattctcat aattggacga tgcagctgca
    21421 catccatgct tatcgtaact gtaatacaca aatgttggaa aaattagggc ccgataccgg
    21481 ctatgatgga atgaatgatc tttctttgac tattcctctg caaaaattat tgaaccgtgc
    21541 agaagaaacg gatcagttgc caaagacgat cctttattca ttgaatccga atgactatcc
    21601 tgcgatttta gctttgatgg gctgtttcca aaaagaacag aatggaaaac tgcagttagg
    21661 ttctggatgg tggtacaacg atactcgagc tggtatgcgc gatcaattga cacaatttgc
    21721 tgatggtagt gctttgggga attttgtcgg catgctgaca gattcaagaa gtttcctgtc
    21781 ctacactaga catgaatatt tccgtcgtgt tctttgtgaa tttttaggcg aaatggtcat
    21841 gcgaggagaa gcacctgaag atgaacaact tttaggaagt ctagttcaag cgattagtta
    21901 tacaaatgct aaaaattact ttggcttttt tgcctaattg attaatagta acagtaacga
    21961 atcaaaaaca ggatagtgaa ataacggaat ccgtttatcc acgttttaga gaagaagacg
    22021 gaccaaattt
//
LOCUS       DAXLPY010000046        21969 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.046, whole genome shotgun sequence.
ACCESSION   DAXLPY010000046 DAXLPY010000000
VERSION     DAXLPY010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.046"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            3..815
                     /locus_tag="ACF3UF_001824"
     CDS             3..815
                     /locus_tag="ACF3UF_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFD3671927.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            812..1612
                     /locus_tag="ACF3UF_001825"
     CDS             812..1612
                     /locus_tag="ACF3UF_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFD3671928.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1773..3041
                     /gene="rseP"
                     /locus_tag="ACF3UF_001826"
     CDS             1773..3041
                     /gene="rseP"
                     /locus_tag="ACF3UF_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFD3671929.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3109..4818
                     /locus_tag="ACF3UF_001827"
     CDS             3109..4818
                     /locus_tag="ACF3UF_001827"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFD3671930.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            5030..9388
                     /locus_tag="ACF3UF_001828"
     CDS             5030..9388
                     /locus_tag="ACF3UF_001828"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFD3671931.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9533..10006
                     /gene="rimP"
                     /locus_tag="ACF3UF_001829"
     CDS             9533..10006
                     /gene="rimP"
                     /locus_tag="ACF3UF_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFD3671932.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10029..11204
                     /gene="nusA"
                     /locus_tag="ACF3UF_001830"
     CDS             10029..11204
                     /gene="nusA"
                     /locus_tag="ACF3UF_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFD3671933.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11226..11519
                     /locus_tag="ACF3UF_001831"
     CDS             11226..11519
                     /locus_tag="ACF3UF_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFD3671934.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11516..11827
                     /locus_tag="ACF3UF_001832"
     CDS             11516..11827
                     /locus_tag="ACF3UF_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFD3671935.1"
                     /translation="MNTVNRQEAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11840..14146
                     /gene="infB"
                     /locus_tag="ACF3UF_001833"
     CDS             11840..14146
                     /gene="infB"
                     /locus_tag="ACF3UF_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFD3671936.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNPNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14173..14520
                     /gene="rbfA"
                     /locus_tag="ACF3UF_001834"
     CDS             14173..14520
                     /gene="rbfA"
                     /locus_tag="ACF3UF_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFD3671937.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14677..15133)
                     /locus_tag="ACF3UF_001835"
                     /pseudo
     CDS             complement(14677..15133)
                     /locus_tag="ACF3UF_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            15298..17660
                     /locus_tag="ACF3UF_001836"
                     /pseudo
     CDS             15298..17660
                     /locus_tag="ACF3UF_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
     gene            18028..18951
                     /gene="truB"
                     /locus_tag="ACF3UF_001837"
     CDS             18028..18951
                     /gene="truB"
                     /locus_tag="ACF3UF_001837"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFD3671938.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            18955..19896
                     /gene="ribF"
                     /locus_tag="ACF3UF_001838"
     CDS             18955..19896
                     /gene="ribF"
                     /locus_tag="ACF3UF_001838"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFD3671939.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            20248..21033
                     /locus_tag="ACF3UF_001839"
     CDS             20248..21033
                     /locus_tag="ACF3UF_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3671940.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            21046..21897
                     /locus_tag="ACF3UF_001840"
     CDS             21046..21897
                     /locus_tag="ACF3UF_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFD3671941.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
BASE COUNT         7476 a         3844 c         4840 g         5809 t
ORIGIN      
        1 gaatgttacg tttttttccg caaaaaaaca aatatattca agaaaaaagc gaatttcaat
       61 ttaataccga tggaccaatt cctcagcaca ttgccatcat catggacggc aatggtcgtt
      121 gggcgcaaaa ccgtcgtttg ccacgagttg ctggccataa agaaggcatg gaaacagtaa
      181 agaaagtcac aaaaaaagca tcaaggcttg gagtgaaagt gttgacgctt tatgcctttt
      241 cgactgaaaa ctggaagcga ccaaaagatg aagtaagttt tctcatgcaa ctacctgtcg
      301 acttctttga tacgttcgta ccagaattga ttaaagaaaa tgtcaaagtt catgtcatgg
      361 gttatgaaaa cgtattgcca gaacatacgc aagatgctgt aagacgtgca attgagcaaa
      421 caaaaaacaa tactggaatg gtattgaatt ttgctttgaa ttatggaagc agagcagaga
      481 tcgtgactgc tgtccaagaa attgccgaag aagtagcaaa aggagaaata cacgcagaag
      541 aaatcgatga tgaattgatt gctaagcatt taatgacagg tttcttgcct aaagagttac
      601 aagatcctga gctgatgatc cgtacaagtg gagaagagcg aattagtaat tttctgttat
      661 ggcagatcgc atatagtgag ctgtatttta caaaagcgct ttggcctgat tttgatggtg
      721 cgcatcttga agaagcaatc gcctcttatc aaaatcgaga ccgtcgattc ggcggtgtaa
      781 aaaaaacaga agatgagaaa ggggatcagt catgaaacaa cgtgtggtca cagcagccgt
      841 ggcgctagtc ttgtttattc cgattatatg gatcggaggc atagcggttg agcttacagc
      901 agcaatctta gcagtaatag gagtttacga gctgtttcgg atgaaaggat tgacactctt
      961 aagttttgaa ggagttttat ccgccgttgg tgcagtgtta cttgttttgc caaaagaaag
     1021 atggtttttc tttcttccag agaatgtaag tacatttatg ttattttatc ttatagttat
     1081 gattctttta ggaacatcag ttatttctaa aaatacgtat acgattgatg aagcaggttt
     1141 tcctgtgctt gtcagcttgt atgtgggaat aggtttccag aattttgtca atgcacgaac
     1201 agaaagcttg gctgttttga tatttggtct atttattgtt tgggcaactg atatcggagc
     1261 atatatggtt ggtcgacgtt atggtcagca taagttaagt cctgatattt cgcccaacaa
     1321 aacgattgaa ggtgcgctcg gtggtattgg tagtgctgtt gtagtcgcat ttctttattt
     1381 attgctatac ccagcaaaag aactatttaa tcatggtatg tttgtcatgc ttctgatgac
     1441 gattattttt tcagcagtcg gacaatttgg tgatttggtc gaatctgcaa tcaaacgtca
     1501 ttatgatgtg aaagactcgg gaaatatctt accaggccat ggtggaatct tagaccgttt
     1561 cgacagtttg ctgtttgtat ttcctatcat gcatttattt ggcattattt agtaagtata
     1621 cctgcgtttc tttgtgaatt tcataaaaga cgcaggtttt tatttttcat tatattgata
     1681 ctattggtgt ctttggtata ctatggtaaa attatagtgt tttatcgttg ttttataaaa
     1741 aacacaaaaa acaagtaaag gagaaaaaag ctatgaaaac gattctgaca tttatcatcg
     1801 tttttggtat attagtgatt gttcatgagt ttggtcattt cttctttgcg aaacgatcag
     1861 gaatcctcgt tcgcgaattt gctatcggta tgggtccgaa aatttatggg catcaagcaa
     1921 aagacgggac aacatatacg cttcgcctat tacctattgg cggttatgtt cgaatggcag
     1981 gcaatgggga tgatgaaaca gaaatggcac caggaatgcc tctttctctt ttactaaatt
     2041 ctgacggcat cgtagagaag ataaatttaa gtaagaaaat ccaattgaca aatgctatcc
     2101 cgatggaatt gagccgttat gatttagaag atgagctgac tatcactggt tatgtgaatg
     2161 gagacgaaac agaagtagta acctaccctg ttgatcatga tgcgacgatt attgaaaacg
     2221 acggaacaga aatcagaatt gcgccaaaag acgtacagtt ccaatcggct aaattgtggc
     2281 agcgtatgct gaccaacttt gctggaccca tgaataactt tattttggca atcctgttat
     2341 tcatcattct ggcatttatg caaggtggtg ttcaagtgac gaacactaat cgcgtaggag
     2401 agatcatgcc taatggagct gcggcagaag caggcttaaa agaaaatgat gaggtagtca
     2461 gtgtggacgg aaaagaaatc cattcatgga atgatctgac aacagtcatt acgaaaaatc
     2521 cggataaaac attagacttt aagatcgaac gagaaggtca ggtgcaatct gtcgacgtga
     2581 caccgaaatc tgtagagtca aatggcgaaa aagttggcca acttggtata aaagccccaa
     2641 tgaatacagg ttttatggat aagatcattg gagggacgcg tcaagctttc agcggttcat
     2701 tggaaatttt caaagcctta ggatcactat ttacaggttt cagtttagat aaattaggcg
     2761 gacctgtcat gatgtaccaa ttgtcttcag aagcagcaaa tcaaggtgta acaactgtta
     2821 ttagtttgat ggcgcttctt tcaatgaatc tcggaatcgt caatctgctt ccgattcctg
     2881 ccttagatgg cgggaaatta gtcttgaata tttttgaagg gattcgcggg aaaccattaa
     2941 gtcaagaaaa agaaggaata ttgacattag ctggctttgg atttttaatg ttgttgatgg
     3001 tgctagttac atggaacgat attcaacgat tctttttcta gaaaaagttg acaaataggg
     3061 tataataaca aacgataact attttgagga aataaaggag tatatagaat gagacaatca
     3121 aaaatgttga ttccaacatt acgcgaagtt ccaaatgatg cagaagtatt aagccatcaa
     3181 atcttgctaa gagctggata tatccgccaa gtatcagcgg gtatttattc atatctgcca
     3241 ttagcaaatc gtgtattgga aaaactgaaa cgcattatgc gggaagaatt tgaaaaaatc
     3301 ggagcggtag aaatgctgat gcctgccatc ttgccagcag aactttggga agaatccggg
     3361 cgttacgaaa catatggacc aaacttgtat cgtttcaaag accgcaatga tcgaaaaatg
     3421 atccttggac caactcacga agaaactttt actgatttga tgcgtaatga aatcaattca
     3481 tataagaaat tacctttaaa tctttatcaa atccaaccta aatatcgtga cgaaaaacga
     3541 cctcgcttcg gtttgcttcg cggaagagag tttatcatga aagatgcgta ttctttccat
     3601 gcaacggaag aaagtttgga cgagacatat aaagattacg aaaaagccta caccgaagta
     3661 ttcaagcgtt gtggcttaga atttcgctcg attatcggag acggtggcgc aatgggcggg
     3721 aaagactcaa aagaattcat ggcgatctca gaaatcgggg aggatacgat ctgttattcg
     3781 actgaaagtg attatgctgc aaacttggag atggctacaa gctactatgt atcaaaaaaa
     3841 tcgcatgaaa cacagcttga attggagaaa gtagctacac ctaacgtaaa atcaattgac
     3901 gaagtagcag atttcttttc tgttgaacct caaaaaatca tcaagtctgt attgttcatt
     3961 gcggatgaac aacctgtcct tgttttggta cgcggagacc atgaagtcaa tgacgtaaaa
     4021 ctgaaaaact ttttatctgc tgacttttta gaagaagcaa cagaagaaga agcacaaaaa
     4081 tatctaggtg ctgagtttgg ttctgtcgga ccagtcggtg tttcagatga cgtaaaagta
     4141 tatgcagacc gttatgtcca agatttagcg aatgccatta ctggagcgaa cgaaacagga
     4201 ttccactata aaaatgtgaa tccagaacgc gatttcactg tactttctta tgaagatctt
     4261 cgttttgtac aagaaggaga tccttcacca gacaacaatg gtgttcttgc ctttactcga
     4321 ggaatcgaaa tcggacatat cttcaaaatc ggcactcgtt acagtgaatc tatgggagca
     4381 actgtactag acgaaaatgg acgagaaaaa tttgtgatta tgggctgtta tggtatcggt
     4441 gtaagtcgtt tattatcagc aatcgtagaa caacattcag atgaacaagg aatcaactgg
     4501 ccaaaaggaa ttgcgccatt tgatttgcat atcgtccaaa tgaatctaaa agacgaatac
     4561 caaacaaacc tgacgaatga actagaagaa gcgatgacaa aagctggcta tgaagtactg
     4621 gttgatgaca gaaatgaacg cgcaggagtg aaattcgcgg attctgattt gattggctgt
     4681 ccaatcagaa tcactgtcgg taaaaaagca gtggatggaa tcgtagaagt gaaaatcaag
     4741 aaaactggcg aaatggttga agtacgtaaa gaagaattgg tgaatacttt accaatcctc
     4801 ttgaaccaag gcgaataata agcgttaaaa cacagaaaat aaaaatagct gaatcagctg
     4861 tttttgacaa tctgatgatt cgcttttaaa attggaactg cgatttgaat cgcagttcca
     4921 attttttaat gtaaaactca gaaaaaacga gtatactaaa aggtactgaa aaagaagagg
     4981 ataagatgcg atcaattgca ttgtttctca tcagaaaggg cgtatatctt tgtcagaaaa
     5041 acgagattta tttgaaaaac tgttggaaca aatccaacta gaggaagcag aaaaaaatca
     5101 tccactgctt actgctggtg aaatggatag tgtagtggtc catcgtaaat cgcgtttatg
     5161 ggaatttacg ctgcattttt ccaaaatttt gcctattatg ctatatcggt cattgactca
     5221 gcatctgact atcgctttta aagatattgc acaagtcaaa ctgaatatct tagcagatga
     5281 ccagacattc gatgaacagc tcttgcaaga ttactgggcc caagctttgg aaaatcagca
     5341 atgcgataca ccactagcac agcaagtatt gaaaacgcag gtacctgtga taaaagatcg
     5401 taaagtcatc ttgccaatcg acagtacagg agctatttct tatttgaagc aacaatactt
     5461 gccattagta gaagagttgt tcgtcagtta cggattccca aaatttcgta tcgaaccaga
     5521 agtggatgag cagcaagcgg aacgagtatt gaaacttttt gaagaacgca aacaagaaca
     5581 ggcagaagcc tttatgaagc aagcagctga aagtctagtt gtccacgaac aaaagaaaaa
     5641 ggaaagaaaa gagcaatcgc cagctcttga aggacccatc cacatccagc taggacgaaa
     5701 tattccagcc gatgaaccaa cgacaccaat gatcagtatc gttgaagaag aacgaagagt
     5761 cacacttgag gggtacgtat tcgacaaaga agtcagagaa ctacgttcaa aacgcaagat
     5821 cttgactttg aaaatcacag attatacttc atcatttatc gtcaaaaaat tctcgaacgg
     5881 cgaaaaagat gaacaagtat ttgatgcgat cagtgtcggt agctggttaa aggtacgagg
     5941 aagtattcaa gaagatacgt ttgtccgtga tttggtcatg aatgcgcaag atatcataga
     6001 agtcaaacat acacctcgca aagattatgc tcctgaaggg gaaaaacgag tagagcttca
     6061 tgttcatagc aatatgagta cgatggatgc aacaaacagc atctctgatc ttgtggcaca
     6121 agcagggaaa tggggacacc gagctatcgc cattacagac cacggtggtg cgcaagcctt
     6181 tccggaagca catagtgctg gaaaaaaagc aggtgtgaaa atcttatacg gcgtggaagc
     6241 gaatgtcgta gatgatggtg tcccaattgc ttataatgat gcacatgaag cattgagtga
     6301 agccacatat gtcgtatttg acgtggaaac gacaggattg tctgcagtat atgacacgat
     6361 catcgagcta gccgcagtca aaatgtataa aggaaatgtg atcgaaagct ttgatgaatt
     6421 tatcgatcca ggacatcctt tgtcacgaac aacggtagat ctgactggta tcacggatgg
     6481 aatggttcga ggatcaaagt cggaagaaga agtattgcgg atgttccttg aattttcaaa
     6541 agatacaatt ttggtagccc acaacgcggc ttttgatatg gggttcttga atactagcta
     6601 cgcaaggtat ggtattcctg aagcggccaa tccagtcatt gatacgttgg aattagctag
     6661 atatctgtat cctcaattca aacgtttcgg attaggtgtg ttatctaaaa aatttggtgt
     6721 cagcttggaa cagcatcacc gagcaatcta tgatgctgaa gcaactggtc acttagcatg
     6781 gatctttgtg aaagaggcaa tggacaatca taacatgctt tatcatgatc agctaaatga
     6841 gcatatcgga gaaggagatt cttacaaaag ggctcgacct ttccatgtaa cgattttagc
     6901 aaaaaatcag gcaggactga aagatttgtt caaactgatt tcaatgtcga atgtcgaata
     6961 cttcgaacgc gtcccacgaa taccacgctc ccaattgaaa aagatgcgtg aaaatctatt
     7021 gatcggctca gcttgtgata agggagaaat attcgaagcc atgatgcaaa aaggggtaga
     7081 agaggcaaga aaccgagcaa aattctacga ttatattgaa gttatgccaa aagcggtcta
     7141 tgcgcctttg atcgagcaag aattggtaaa aaatgaacat gatttggaag aaattatcca
     7201 aaatttggta gaaatcggaa aaagtttgga taaaatcgtt gttgcaacag gtaatgtaca
     7261 ttatctgaac gaagaagatg ccatttaccg aaaaattttg atcaattcta tgggcggagc
     7321 gaatccgttg aatcgtcata gtttgccgga tgtccatttc cgaacaaccg atgagatgct
     7381 aactgcattt cactttttag gggaagaaac agcgaaagag atcgtagtag aaaatacgaa
     7441 taaaatcgca gatatctgcg aagaagtgat tccagtcaaa gatgaacttt atacaccgaa
     7501 gattccaggt tcagaagatg aaatatcaga attgagttac acaaaagcaa aacaaatgta
     7561 cggagatccg ttacctgaga tcattcaaaa acgattaaaa aaagagttga attctattaa
     7621 tggtaatggc ttctcggtta tttatctgat cgcccaaaaa ttagtgcata aaagtaatga
     7681 agatggctat ctagtaggtt cacgtggctc tgttggctct agctttgttg cgacgatgac
     7741 aggaatcact gaagttaatc cgttagcccc tcattattat tgtccagagt gccaatattc
     7801 cgagtttttt gaagatggta cgtatggttc tggatttgac atgccagaaa aacaatgtcc
     7861 aaaatgtggt gcacgcttaa acaaagacgg tcatgatatt ccatttgaga catttttagg
     7921 attccatgga gacaaagtgc ccgatattga tttgaacttc tcaggtgatt atcaagcaga
     7981 agcccataac tatacgaaag tattgtttgg cgaagactat gtttaccgtg ccggaacgat
     8041 tggtacagtc gccgacaaaa cagcatatgg ctatgtaaaa ggatacgaaa gggacaataa
     8101 tctgcagttt cgaagtgcag aagtcgacag attagcaaaa ggcgctactg gagtcaaacg
     8161 gacaaccggc cagcatccag gggggatcat cgttattccc gattatatgg atgtctatga
     8221 ttttacgccg atccaatatc cagcagacga tcaaaattcg gaatggaaaa cgactcattt
     8281 tgattttcac tcgattcacg ataatgtatt gaaattagat attctagggc atgatgaccc
     8341 aactgttatt cggatgcttc aagatttatc agggatcgat ccacaaacga tccctacgga
     8401 tgacccggaa gtgatgcgga tatttgccgg tcctgaagta cttggagtaa gtcaggaaca
     8461 aatttattcc aaaacaggga cattaggtat tccagaattc ggcactcgtt ttgttcgagg
     8521 gatgctagaa gaaacgcatc ctacaacttt tgcagaacta ctgcaaattt ccggactatc
     8581 tcatggtaca gacgtatggt taggaaatgc ggaagaattg attcgacgag gagatgcgac
     8641 actggcggaa gtaatcggct gtcgtgatga tattatggtt tatttgatcc atgctggatt
     8701 agatagcggg atggcattta aaatcatgga aactgttcgt aaaggacaat ggaacaagat
     8761 ccctgatgaa ttgcgagaaa cctatctatc ggcgatgaaa gaaaataatg tgcccgactg
     8821 gtatatcgat tcttgttcaa aaatcaaata tatgtttccg aaagcccatg ctgcagctta
     8881 cgtattgatg gctcttcgtg tcgcttattt caaggtttat ttccctattt tgtattactg
     8941 tgcatacttt tctgtacgtg cagacgactt tgatctagtc tccatgtgca aaggaaaaga
     9001 tgctgtgaaa caagcaatga aagaaatcac ggacaaagga ttagatgctt ccgtaaaaga
     9061 aaagaatcaa ctgacagtgc tggagttagc caatgaaatg ctggaacgag gattcaaatt
     9121 tggaatgatt gatttgtata aatcggatgc cgttaacttt gttattgaag gtgatacgtt
     9181 gatcgcacca tttagagctg tcccaagttt gggaaccaac gtggcaaaac aaatcgttga
     9241 agcaagaaaa gacggtccat ttttatccaa agaagatctt gccacccgcg gtaaagtttc
     9301 aaaaacattg atcgaatata tgaacgacaa tggcgtattg aaagatctac cagatgaaaa
     9361 tcaattatcg ttattcgata tgctataagc atctgttttc ctgtctgctt gtaattttaa
     9421 gcagagtatg gtatagttct tataggtaat gatactaact gtgagtgagc ggatttttcg
     9481 ctcactcttt ttaatggaat tacgcactta attttttaag gaggcgaaac ttttgagtag
     9541 cgtcgttgaa acagtcacag aaatggtgac accgatttta gatgaacaaa attttgaact
     9601 tgtcgaagtc gaatttgtaa aagaaggaaa aagctggttc ttacgagtat ttattgacaa
     9661 agaaggcggt atcgatatcg aagaatgcgc ctttgtcagt gagaaactga gtgaaaaact
     9721 tgatgcagca gatccagatc cgattcctca agcctatttc ctggaggtat cctccccggg
     9781 agcagagcgg ccattgaaaa aagaaagcga ctatgaaaag gcacttggtg attatgtcca
     9841 tgtctcctta taccaaccag tagatggcga aaaacaatat gaaggatttc ttcaatcatt
     9901 tgatgctgaa cagcttacat tgaaaatacg cataaaaaca cgagaaaaag aattgacttt
     9961 tgaccgaaaa aatattgcaa aagctcgctt agctatccaa ttttaatcac ggagaggaat
    10021 cagaaaaaat gagtaaagaa atgttaaatg cgttagacgc tttagaagct gaaaaaggga
    10081 tctcaaaaga aatcgtgatc gatgctttag aagcagcatt ggtttctgca tacaaacgtc
    10141 actatggcca agcacaaaac gtcgaagtgg aatttgatca gaaaaaagga aagatccatg
    10201 tctatgcggt aaaagaagta acggaagaag tgatggattc acagttggaa gtctcattga
    10261 aagatgcact tttaatcaat ccagcatatg agatcggtga tacgatccgt tttgaagtaa
    10321 caccaaaaga ttttgggcgg atcgctgcgc aaacggctaa acaagttatt ttacagcgtg
    10381 tacgtgaagc agaaagaacg attatttata acgaattcag tgcttatgaa aaagacatca
    10441 tgcaaggaat cgtcgaacgc caggataaac gttatattta tgtcaatctt ggtaaaattg
    10501 aggcagttct ttctaaacaa gatcaaatgc caaatgaatt ttatcaacca catgatcgaa
    10561 tcaaagttta tgtttcccga gtagaaaata cgtctaaagg tccgcaagta tttgttagcc
    10621 gcagccatcc agacctattg cgccgcttat ttgagcaaga agtaccagaa gtctatgatg
    10681 gaatcgttga aattgtcagc atcgcccgtg aagctggcga tcgttcaaaa gtggcagttc
    10741 gctcaaatga tccaaatatc gatgcagtcg gtacatgtgt cgggccaaag ggacaacgag
    10801 ttcaagcaat cgtcaatgaa ttaaaaggcg aaaacatgga tatcgtcgaa tggaatgaag
    10861 atccagctgt attcattgca aatgcattga atcctgcaca agtcatggat gtgatcttcg
    10921 atgagacaaa tccaaaggcc tgcacagttg tcgttccaga ctaccaatta tcgctagcaa
    10981 tcggtaaacg cggacaaaac gcacgtttag ctgctaaatt gactaaccat aaaatcgata
    11041 tcaaatcaga atctgacatg acggaatttt atgaaaatca agaacaacaa aaagaaacag
    11101 aagaactgca tgatgaagca atcgttcagt cagatttaac agacgatgaa tatgaaacaa
    11161 ttgcattcaa caatgaaacg gtcgaagaaa aaccagaagc ttaactttag taaggaggca
    11221 aagagatgaa acaaaggaaa attcctttac gcaaatccgt ggtttcaggt gaaatgaaac
    11281 ctaaaaaaga gatggtccga atcacccgtt caaaagaagg ggaagtatcg atcgatccaa
    11341 ctggaaaaat gcctggacga ggagcgtatg tctcacttga gccggaagaa gtacaacaag
    11401 cttgggataa aaaaattctc gatcgagtac tcgaaacaac attaacagat gagttttatc
    11461 aagaacttct tgactatgtc actcaccaaa aagcacgtaa agagttattt ggaaaatgaa
    11521 tacagttaat cggcaagaag ccatgaatct catcggtcta gcgatgcgcg cgggaaaact
    11581 aatcacgggt gaagaactga ccattgctga aatccgcaaa caaaaagcaa aattggtgtt
    11641 tgtggcaacc gatgcaagcg agaatacaag aaaaaagata aaagataaga gttcatatta
    11701 tgaagttcct tgctttgagc tattttctga agcagaaatc acgcagatga tcggaaaacc
    11761 tcgcaaggta ttcggaataa tggatgccgg atttgcgaag aagaccaagg agctaattga
    11821 aggttaggaa ggtgattgca tgggcaacaa aagaatctat gaattagcaa aagaactcaa
    11881 aaaatctagt aaagacgtcg tggaaaaagc acaacaactt ggcatcgatg tgaaaaacca
    11941 tatgggtgcg attactagca atgatgagaa gaaattgcaa caagcgttca aaaacccaag
    12001 cacgaaacaa caagctgcac aacaagcaag cagaaaacca gccaatcaac agccgaacga
    12061 tcaacgtaaa aaagaaacaa cgaacaatca acaaaaaaat aaaaataacc gcagttatca
    12121 agatcgcggt caagggagcg gtcaagtgaa tcaaggaaaa aaaccaacaa caaacccaaa
    12181 taatacggga aataccagca gccaaaatcg tcaaggaacg agccaaggcg gcaatcaaaa
    12241 ccgtactaac aataacaaca aaccaaacaa taacaatcgc ggcaaattta ataataataa
    12301 ccgtaatcgt tataataaaa aaggtaaaaa aggcaaacag caacaatcaa ctaaaccagc
    12361 tgtaccacca cgcaaattcc gtgaattgcc agatgtatta gagtatactg aaggtatgaa
    12421 cgtagcagat attgcgaaaa aaattcatcg tgagccagca gaaatcatta aaaaattatt
    12481 tatgcttggt gtcatggtca atcaaaacca agcactggat aaagatacga ttgaactgtt
    12541 agcgacggac tatggcatgg aaccacaaga aaaagtccaa gttgacattg ctgatatcga
    12601 taaattcttc gaggcagaag aagtcgatcc agataaatta gtctcacgtc cgccagtcgt
    12661 aacgattatg ggacacgtag accatgggaa aacaacttta ttggatacat tacgccattc
    12721 acgtgtaaca agcggcgaag ccggcggaat cacacagcat atcggtgcct accagatcga
    12781 tattgatggt aaaccaatca ctttcttgga tacaccagga catgcggcct ttacaagtat
    12841 gcgtgcacgt ggagcaagta tcacagatat cacgatctta gttgttgctg cagatgatgg
    12901 cgtcatgcca caaacagttg aagcaatcaa ccatgccaaa gctgcaggcg ttccaatcat
    12961 cgtcgctgta aataaaattg ataaaccagg tgcaaaccct caacatgtta tgcaagaatt
    13021 aagtgagtat gagttaattc ctgaagcatg gggtggagaa acgatctttg ttgagatctc
    13081 agcgaaattc ggccaaaaca tcgaagaatt gctggaaatg atcctgttag tcgcagaagt
    13141 agaagattta aaagcagatc caacacaacg cgcaatcgga acagtgatcg aagcacgtct
    13201 tgataaaggt aaaggtcctg tgtcaacctt acttgtccaa gaaggaacac ttcatgttgg
    13261 tgacccaatc gttgtcggta atacttacgg acgtgtccgt gtaatgacaa acgatcttgg
    13321 ccgtcgcgat aaagaagcag gacctgcaac gccagtagaa atcactggct tgaatgatgt
    13381 acctcaagca ggtgaccgtt tcgtagtctt cgaagacgaa aagacagcac gtgcagcggg
    13441 tgaagaacgc gcgaaacgtg cattattaga aaaccgtgct gccacaagcc gtgtgacttt
    13501 ggataactta tttgaaagcc tgaaagaagg cgaattgaaa gaagttaacg taatcatcaa
    13561 agcagatgta caaggttcag cagaagcact ggctgcatca ttgaagaaga ttgatgtgga
    13621 aggtgtccgt gtaaaaatcg tccattcagc tgtcggagca atcaatgaaa gtgatgtaac
    13681 cttagcagca gccagcaacg ctattatcat cggtttcaac gttcgtccta caccgcaggc
    13741 aaaagtgcaa gctgatactg aagaagtcga tattcgtctt caccgtatca tctataaagc
    13801 catcgaagaa atcgaaactg cgatgaaagg gatgctagac cctgaatttg aagaaaaaat
    13861 caccggtcaa atgatcgttc gtgaaacctt caaagtttct aaagttggta cgattgcagg
    13921 tgcctatgta acagaaggat atattcgtag agatagcggt gtccgtgtaa tccgtgacgg
    13981 aatcgtaatc tatgaaggcc aacttgcaag tctgaaacga ttcaaagatg acgtgaaaga
    14041 agtcaaaatg ggttatgaat gtggtgcaat gattgaaaaa ttcaatgaca tcaaagtaga
    14101 tgacgtaatt gaaggattta tcatggaaga agtcaaaaat gactaaaaac tgataaaagg
    14161 aggccaatca ttatggctaa ctaccgtgac cgccgagtcg gtcaagaaat cttaaaagaa
    14221 gtcaatgata ttttgcgcaa aaaggtccgt gaccctcgtg tggagaacgt aacgatcaca
    14281 gatgtgaaag ttacggggga cttacagcaa gcaacgatct attacagcat tttatctgac
    14341 ttagcatcag ataagaaaac agcacaagat ggattgaata aagcatcagg attgattcgt
    14401 cgagagttag ggcacaatct aagtatttat aagacacctg aattgttctt tgaacttgat
    14461 gaatcagttg tctatggcaa ccatatcgat gaattgcttc gcgacttgaa caaagactaa
    14521 tcaaaaactc ccgcaaatcc tgtgaaatca ggggttgcgg gatttttttg ttttcattaa
    14581 gacgtattac ctaagagttc catgacttta gtcttgcggc gtgtcagcta accaaaaaag
    14641 agaaaaagaa aagtaaaaaa ttcgactttc ttttttctag tagtatataa atttttgcat
    14701 atagataaag atcaagatac cgataacgga agctagattg taatctattt tagtgacagt
    14761 caggtatagc caagtaacta gaagatcagt ggaacctgca ccataaaagt ttgagtttgt
    14821 cggtccgttg acagttaaaa gaaaaatcac gttgaagtta ttgatatttc cgattacgcc
    14881 gcttcgattt ggtcacgatc caaattttgg ataatccctg tagaaattag catagtagct
    14941 gggataccaa ttcacatatt gacaaagata acagagactt ttacataaaa cggatcaatc
    15001 aggaaaggaa ttgctcgatc cagccccagt tttccagcaa tgtgttaact ggcccagcgt
    15061 cattcagcaa attatgcatg atgaggagcg aaatgaactg cggaacagcc attgtgataa
    15121 cgacaagttt tttggatcaa tgtaaaaaac gtcagcgaaa ggaaaaattt cgtggttttt
    15181 tatacctgtt catttggcta gatataaaat ccaaacaaat gaacagaagt gcttattagg
    15241 tttcaattgg gagtatctgc gctagaataa gagtaataat gaaaaggagt gttatgtatg
    15301 gattattcta gtaaagaata ctttgataaa atgacggctt ggtggcgtgc tgctaattat
    15361 ctttctgttg ggcaacttta tcttaaagat aaccccttac tgagacgtac actgaaaccc
    15421 gaagatgtca aaaaacatcc aatcggtcat tggggaacga ttcctggcca aaattttatt
    15481 tatgtccatt tgaaccgagt catcaataaa tatgatttga acatgtttta tattgaaggg
    15541 ccaggacacg gcggacaagt catggtatcg aatgcttatt tagatggaag ttacacagag
    15601 atctatccag aagtaacgga agatgagaca ggaatgcaaa aattattcaa acgattttca
    15661 tttcctggag gcattgcttc tcatgcagca ccagaaacac caggttctat ccatgaaggc
    15721 ggagagcttg gatactctct ttcacatgca gtcggagctg tattagacaa tcctgaagta
    15781 atctctgctg tcgtgattgg tgatggtgaa gcggaaaccg gtcctttagc tggaagctgg
    15841 ttctcaaatg tctttatcaa tccagtgata gatggagctg ttttaccgat ccttcattta
    15901 aatggtgcaa aaatagccaa cccaacgatc ttggcacgta aatcagatgg agaattagca
    15961 aattacttta acggacttgg ctgggaacct ttctttattg aaggaaatga ttcagaaaaa
    16021 ttaaatcctg ttatggctga aaaaatggat caagcaatcg agaaaattaa atccatccaa
    16081 aaagaagctc gcctgaagac agcaacagat gtcgtgatgc caaaatggcc agtattgatc
    16141 gtacgcacac caaaaggatg gaccggtcca aaagaatggg acggggaacc aattgaagga
    16201 accttccgag cacaccaagt accgattcct gtagatcaag aacatatgga tcatgcagat
    16261 gctttactcc gttggctgaa atcctatgaa ccagaaaaat tatttgatgc acaaggacgt
    16321 attttagaag aaatcagaga aatcgcgcct actggtgacc aaagaatggc aaaaaatcct
    16381 atcaccaatg gtggaatcga tccaagaccg cttattatgc cagattggaa aaaatatact
    16441 ttgcaatttg aaaaaccagg ctccgttaaa gcagaagata tgaccgaact tggtaaattc
    16501 gttcgcgaga tcattgagaa aaatccagaa aatttccgta tatttggacc agatgaaaca
    16561 aaatcaaacc gattgaatca agttttcaaa acgacaaatc gccaatggat ggaaaaaatc
    16621 gaaccagaaa atgatgaatg gctttcgcca tctggtcgcg tcatcgacag tcaattatcg
    16681 gaacaccaag atgaagggtt cttagaaggg tacgttctga ctggacggca tggttttttg
    16741 caagttacga atcattcttg cgagtggttg actctatgtt gactcagcac ttcaaatgga
    16801 tgcggaaatc acatgacctt tcttggcgaa atgattatcc ttcgctaaat ctcattgcaa
    16861 gctcaacagt cttccagcaa gatcacaatg gatatagcca ccaagatcca ggaatattga
    16921 cacatttggc agaaaagaag gcggagttca tccgtgaata tctgcctgcg gatgcaaata
    16981 cattgctcgc agtcatggat aaagcattcc gctcgtcaga aaaaatcaat ttgatcatct
    17041 cttccaaaca tccgcgtgct caattttact cagcagaaga agcagccgtc ttagtgaatg
    17101 aaggcttgaa aatcattgat tgggcttcga cagcaaaaga ggaggaacct gaattggtca
    17161 ttgctgctgc aggaacggaa tctaacttag aagcattagc agctgtaact ttgctgctgg
    17221 aagaattccc aaaactaaaa attcggttca tcaatgtcgt agatttattg aaattacgtc
    17281 atccaagtca agatccgcgt gggttgagcg atgaagaatt tgatcaatat tttacaaaag
    17341 acaaaccgat cttatttgct ttccacggtt atgaaacatt ggtccgcacg attttctttg
    17401 atcgtcataa ccatcattta atgattcatg gctacaaaga aaatggagat atcacgacac
    17461 catttgacat gcgtgtagta aatgaacttg atcgttatca tttggcaaaa gacgcagctt
    17521 taaaaatcaa aggaagtcaa gcagaagatt ttgcgaaaaa aatggatcag aaattacaag
    17581 aacatcaaaa ctatattcgt gaaaatggta ttgatctgcc agaagtattg gattggaaat
    17641 ggaaaaatct tgaccaataa aatgataaaa tcgatcccgc aaaatagaat tttttacatt
    17701 gattaagaaa ctgaaaaaat aaataaaaaa aacggaaaaa agactggaag aatggccagt
    17761 cttttttttc gtttttggga agtgaaaacc aaactattta cctgtaagcc acccataaat
    17821 ccaatcaaat ggtgcaaaga aaaaatcttc cattctattc cctcctttaa aaaagcataa
    17881 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
    17941 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
    18001 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat tacctttatg gaaagaacgc
    18061 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
    18121 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
    18181 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
    18241 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
    18301 gatatgtctt tatctgaaaa aaaaatagat gaagtgatgg cttcatttat tggtgagatc
    18361 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
    18421 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
    18481 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
    18541 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
    18601 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaggat
    18661 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
    18721 ctgccaatag aaaaaggagt ggaacggttc aaacgagtag atattactga tgaagtatgg
    18781 cagaaagtaa aaaacggtat gagacttgat tatactgtat ttgcgctccc agaaatgccg
    18841 tcagaagaaa ttgctttgtt ttataaagga aaagttgtca gtatttatca gccaaacccg
    18901 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
    18961 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
    19021 gtgctgggat ttttcgacgg cgtgcatatc ggacaccaga aagtcataaa gacaggtatg
    19081 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatct
    19141 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
    19201 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
    19261 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
    19321 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
    19381 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
    19441 ggtgaaaaaa tcagctctac ccgtattcgt ggattactag acagcggaca agtaaaagaa
    19501 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
    19561 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac ggttcatttg
    19621 cctaaagaag gtgtttatgt gtcggaaata aaaattgggg aaacatggta tccagccatg
    19681 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agagttgtat
    19741 attttggact ttaatcaaga tatctatggt gaacatgtcg cggtacgctg gaatcaattt
    19801 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaggaggat
    19861 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
    19921 ttatgtataa ctagcaatta caataaaatg ggtgataaat aagcccagga aaggggctgt
    19981 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
    20041 cggaaataag ccgaaatttc ttgaagctga ccacttctgt cacaacctct ttctttatag
    20101 aaataaaagg acactagcaa ttcatgaaaa cgattgctag agcgtatcat ttgctttaga
    20161 ctatatatct tggtgtacac tcactttaag gcggaaataa aagttatccg taataacagg
    20221 tttaggtatg aaaaaggagt gggtactatg tacaaggaat tagaaaacaa agtcgcagta
    20281 gtaactggtg gctcaaaggg gattggaaca gcgattgctc aacgattcgg gaaagaaaaa
    20341 atgaatgtag ttgtcaacta taactcggat aaagaaggag cagaaaaagc agtcaaagca
    20401 atcgaagagg caggcggaaa agcagtctct gtacaagcag atgtcagttc tgaagaagga
    20461 atacagcgtt tacttgatac ggctttagaa aattttggga cactggacgt ttgggttaat
    20521 aatgctggga tggaaaatca gcatccaacc catgaactta gccttgaaga ttgggaaaga
    20581 gtgttaaaag tcaatttgac tggcgttttt atcggaacga aagcggcttt aaattacttt
    20641 acagagaata ataaaaaagg aaatatcatc aatatgtctt ctgttcatga acagatccca
    20701 tggccaacgt ttgctcatta cgctgcttca aaaggcgggg taaaattatt taccgaaacg
    20761 gtagcaatgg agtatgcacc gaagggaatc agaatcaata gtataggccc tggtgctatc
    20821 cgtacaccta ttaatgcggc aaaatttgat gatcctgaac aaaaagaact cttggaaagt
    20881 atgatcccac taggacgcgt aggtgaacca aaagaaatag cggcgacagc tgcatggttg
    20941 gcttcagacg aatccagtta tgttacaggt attacactat ttgcagatgg tgggatgact
    21001 ttatatcctt ctttccaagg tggaaaagga taagggtgaa taaaaatggg tttattgatt
    21061 gcattgatcc cggcagttgg ctgggggatc cagccactga ttttgaaaaa gattggtggc
    21121 agaccaacaa atgagatatt aggaactggt attggagcgg tgcttgtcgg cttactcgtt
    21181 caattattcg cttctccagc tggtatttca gtgactacat ttttgattag tttactttct
    21241 ggtgcatttt gggttattgg acaaacagga cagtatacat ctttcaactt gattggtgtt
    21301 tctaaaacga tgccaatttc gactgcatta cagttagtcg gaacctcgtt gattggtgtc
    21361 ttcgcttttg gagaatggtc tggaagtatg gggaaaatca ttggagcagc agcaatcatt
    21421 cttcttgtat ttggttctgc tttaacggca atcagtgatg atcctggaaa aaaaggcggt
    21481 atcacaaaag gaattagtct attagcatca acaagtattg gttattgggt atacagtgca
    21541 ttgcctaaac tagttgatgc aagcggactt tccattttct ttccgcaaat gatcggtgtc
    21601 tttttagggg cagtgattta tgtgattttc cgtaaaccaa ccgcattttc tgaagacaag
    21661 agttggaaag caacgatcgt tggagccatc tttagtgtgt cagcattggc ttatattttt
    21721 tcagcaaatg aaaatggggt tgctactgca tatatcatta cacagctaaa cgtagttatc
    21781 tctacattag gcggtatgta catcctgcat gaaaataaga caccaaaaga aaaaaaatta
    21841 acgattatcg gattattgct gatcgtagta ggaagcatgg tcacggtctt tatttgagga
    21901 taaagatggt aaaatttcat ttattaaaaa aatatttgtt tgaaccaaac agtaagtact
    21961 tataaaaaa
//
LOCUS       DAXLPY010000047        21942 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.047, whole genome shotgun sequence.
ACCESSION   DAXLPY010000047 DAXLPY010000000
VERSION     DAXLPY010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.047"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(230..1129)
                     /locus_tag="ACF3UF_001841"
     CDS             complement(230..1129)
                     /locus_tag="ACF3UF_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3671942.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            complement(1139..1495)
                     /locus_tag="ACF3UF_001842"
     CDS             complement(1139..1495)
                     /locus_tag="ACF3UF_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFD3671943.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            1850..2146
                     /locus_tag="ACF3UF_001843"
     CDS             1850..2146
                     /locus_tag="ACF3UF_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFD3671944.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            complement(2790..3743)
                     /locus_tag="ACF3UF_001844"
     CDS             complement(2790..3743)
                     /locus_tag="ACF3UF_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3671945.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(3766..4521)
                     /locus_tag="ACF3UF_001845"
     CDS             complement(3766..4521)
                     /locus_tag="ACF3UF_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671946.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            complement(4518..5477)
                     /locus_tag="ACF3UF_001846"
     CDS             complement(4518..5477)
                     /locus_tag="ACF3UF_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFD3671947.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            complement(5470..6420)
                     /locus_tag="ACF3UF_001847"
     CDS             complement(5470..6420)
                     /locus_tag="ACF3UF_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFD3671948.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            6570..7022
                     /locus_tag="ACF3UF_001848"
     CDS             6570..7022
                     /locus_tag="ACF3UF_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFD3671949.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            complement(7111..9378)
                     /gene="gshAB"
                     /locus_tag="ACF3UF_001849"
     CDS             complement(7111..9378)
                     /gene="gshAB"
                     /locus_tag="ACF3UF_001849"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFD3671950.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(9565..10563)
                     /gene="ftsY"
                     /locus_tag="ACF3UF_001850"
     CDS             complement(9565..10563)
                     /gene="ftsY"
                     /locus_tag="ACF3UF_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFD3671951.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            complement(10574..11383)
                     /locus_tag="ACF3UF_001851"
     CDS             complement(10574..11383)
                     /locus_tag="ACF3UF_001851"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3671952.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            complement(11392..14973)
                     /gene="smc"
                     /locus_tag="ACF3UF_001852"
     CDS             complement(11392..14973)
                     /gene="smc"
                     /locus_tag="ACF3UF_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFD3671953.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            complement(14993..15679)
                     /gene="rnc"
                     /locus_tag="ACF3UF_001853"
     CDS             complement(14993..15679)
                     /gene="rnc"
                     /locus_tag="ACF3UF_001853"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFD3671954.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            complement(16027..17808)
                     /locus_tag="ACF3UF_001854"
     CDS             complement(16027..17808)
                     /locus_tag="ACF3UF_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3671955.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            complement(17834..18748)
                     /locus_tag="ACF3UF_001855"
     CDS             complement(17834..18748)
                     /locus_tag="ACF3UF_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3671956.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            complement(18775..19737)
                     /gene="opp4B"
                     /locus_tag="ACF3UF_001856"
     CDS             complement(18775..19737)
                     /gene="opp4B"
                     /locus_tag="ACF3UF_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFD3671957.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            complement(19737..20681)
                     /locus_tag="ACF3UF_001857"
     CDS             complement(19737..20681)
                     /locus_tag="ACF3UF_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671958.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            complement(20682..21686)
                     /locus_tag="ACF3UF_001858"
     CDS             complement(20682..21686)
                     /locus_tag="ACF3UF_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3671959.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
BASE COUNT         6153 a         4666 c         3872 g         7251 t
ORIGIN      
        1 attataatta aataaaaaat gtatattata ttttttttgt gattatcgtt caaaaaaaga
       61 atacacgctt gcatctagta ctctgcgagt tacaaatcat ccgatcaaat aaacattcgc
      121 tgattatttt ccgcaaaaaa agcagcatat ccacgataaa tggatctact gctcttactt
      181 atccttatgt tttacaaggt attttctttt acacattact aatgctgtct caatacggaa
      241 cgattgtcat cgcttgttca aattcctctt gcaaatgttg tgtttgatag gcctgaaaag
      301 ctgggtgatg ggcacgcaag aggacacgta atttcatagg atcatagctg tctagcaact
      361 gttctttcaa gacaaaatct cgggtcagct gccattcata ataataacca aaaggtctgc
      421 agctgtaaat cgtgtgaccg atggatttat cttcaaagcg acgatgcgta tggccaaaaa
      481 ctacttgttt gatatttgaa taacggtcaa gtaattctcc gaatgattct gatcctaaaa
      541 atgcatttaa tttgttccaa cgctcataag gagcagattg atacatgata aatgcccgtt
      601 taggaacgaa atgagtggat aaaatcacct caagtttttt tgcttccagc tggtctagca
      661 aattttttgc agctgcaagc atttctgcat tgacctcgag atctgttttc ccacgctgga
      721 tgaaccgatc ataccaatac aaacgcttca ttcgtacgat tgcctcgtaa tctttcaatt
      781 cggaaaactg atagtcgtac cagccattca tccctaaaag aacggtctgc tcatttaaag
      841 caatataccg ttcatttaaa aaatgtgggt ctggaaaatg gtccatcatc tgttcattgg
      901 gcacatctgc caactcgtga ttgccgaaat gaaatgtcgt agataatcct ttattgacga
      961 aaaattcgac aacagctagg caacggtcta ctttattagc cgtatctccg gctagatgaa
     1021 gccgagtgat cttgtgcttt tgcaaaactt gccaaagctg catcagctct gattcgccga
     1081 atttattgat gtccacatgt aggtcgctga tgatcgccaa ttttcccatt ttatccctct
     1141 agtcttttcg aacaacttgc aagttgcctt ttctcaagcc gcttggtcct tttaattgta
     1201 aactattata agttggttct aaagcaagtg tggatggatc atccatgtaa agtattgcac
     1261 tgtctttgat tttgattggt ccaactggtg tatcagccac tacagaataa agacttagat
     1321 ctgtttgtgt atcttttttg acaatgatca atcgaaatgc cgtatccaat tggcaactga
     1381 cttggctttc tgcaaatgga ccgtcaccgt tttcgatatc taataaaagt tgatcgtctg
     1441 cttctaattt attcttcaat acttcttgtg cttcttttgt cacttctaat ttcatctgta
     1501 tcacctcatg tcatagaata atcactttat tcatcagatg caactaattt gtctggttct
     1561 gactgttctc aatttattgg aaagtaagtc attcgtttat tatgatttct cttatcacaa
     1621 aagagacaac tttccctttt cttcgttcag tttcttgaac ggaaaaagac ccaaaaagca
     1681 acctgttatt tgtttaacct tattcctttc ttaaataaca aaaaatacta taaaaaataa
     1741 aaaaccttta acaactattg gaaaaagaat tactttttgt tcacggatta ttaacaactc
     1801 ttcggtagag taaacttatc aaataaaaga cttctttgga ggaatcacta tgaaggaata
     1861 tataaaaaac atctatttta tcgaagaaac acaaaatatc gagggttctt atattgaagt
     1921 aaaaacactc tttgtcaatg aagataaaac caaagcattg gatatttata aaaaattagc
     1981 ttcaaaaaaa acgaatagtt ttggattgat attaagcgag tataaaatca aagcagaaga
     2041 gagttatttc tatcaattac taaaacggtg gagtaagctt cccgccgatt tttatcgaaa
     2101 aatgcagatc atcaactatc aaccgcttgc tgagacacat gcctaaatag aggttgtgaa
     2161 atcagtgctt tgagctaata ccgaaggtca gctgattgaa cattgtttag aagagattgt
     2221 gacaactgcg atttgctttg agtaataaga acgctggaca gaaaatagct tctcatattt
     2281 tctagtctag tgggcttatt gccgagaagc agcagatgga acatcgttta gaagagattg
     2341 tgacaactgc gatttgtttt gagtaataag aacgctggac agaaaatagc ttctcatatt
     2401 ttctagtcta gtggacttat tgccgagaag cagcagatgg aacatcgttt aaagaagaga
     2461 tcggtacaaa ataaaaatat ctaaatttaa gttttatcta agtttcgctt tgtacctttg
     2521 attcaaatca aaggaggcga tcttgatgct gaaaaaatgg atcacactat tttttgccac
     2581 tccccattct agaatcaacc cgtatgatgt agataatgaa ttcacgttga aaaaagattt
     2641 ctcaaataaa taaaaaccat ccgtaaaatc atcaatacga ttttacggat ggtttttgat
     2701 aacttctttg aggataggct cttgctattt aagaatgtaa gaaacattat tgttacatag
     2761 tatgagagtt taatcctctg ttatttatgc tatttaaatg cttgattcac atcttcgatc
     2821 atcagtttca ttgattctaa accgcccccg cttaaatacc agacatctgg ttcaagggag
     2881 atgatctgct gatttttacc agcattcgtt tgtgctacca gttcattggc agaaatatca
     2941 tctttgctgt cgtctccacc aatagctttt gttctgtcta ctacaaataa gatatccgga
     3001 tttttttcca gcacatattc ataagaaaca ctttgaccgt gagtggatgc ttcgatttga
     3061 tcatctgctt gttcaaagcc aaataaatca tggatgaaac cgaatctaga accagatccg
     3121 taggctgata attgcccttc attcacaagt gtgactagtg cttttttgtc agtagcttct
     3181 gctttctttt tcgtctgatc gattgcacta gataattcct ctaattgagt tttagcttct
     3241 tcttgcttac caaagatctc ccctaaagca gtgacatttt gctggaaaga ttcccatgga
     3301 tttttcgcat ctaaagaaag gaaaatggtc ggagcaattt gacttagatc tttttgaaaa
     3361 tctctttgtc ggccagaaat gatgattaga tctggctgaa gctgattaat tttttctaag
     3421 tctggttctt ttattccacc tgctgattct acttttttat aggatgaaag atactcagga
     3481 aggctgcttg tagctgctcc aactacctta tctccaacac caagagcatc catcgtatct
     3541 aaagaaccat tgtcgaatac gacgactttt tctggattat ttggcacctc gatttggtct
     3601 ccattactat ctgttatcgt caatgtagtt tcagtttgtg tgctgctttt ttttgtgtct
     3661 gcctgactgg tgttgttgct atttccacat gctgctaaac caaatgatgc tagaatcaag
     3721 atacctacta ctaatttttt catctcttct ctcctaatgt tagttttaga aataaagaca
     3781 gaatctgcgg ccttcaatct cacaaatccg tatgtccatt tcgtataatt catccaatac
     3841 atcttttttt atcatttctt gggtcgttcc ttgcgtaaat aactgtccat ctttcattgc
     3901 aacaatttcg tctgcataac ttgcagcaaa gttgatatca tgaagaacaa taacaattgt
     3961 tttcccgatt tcttgtacta aattttttaa aatctgcatg atttgaaccg caaaattcat
     4021 atctagattg ttcaaaggtt catccagtaa aatataatcc gtgtcttgcg ctagcaccat
     4081 tgcaatatac gcacgttgga gttgaccgcc tgaaagagtg tcaatcgatt gatccgctat
     4141 ttcttctaac ccaatgtgtt ccagtgattc ctgaacgatt tcctcgtctt ttgtcgtcaa
     4201 ttttcctttc gtataaggaa atcgtccaaa ttctactaat tctttcacgg tgatttggac
     4261 atttatttca ttcgattgtc gtaggatcga taattttttg gctaattcat tggatttcca
     4321 agcctttact tcgttatggt ctaaatagat ttcacctgta tcttttggta tcaaacgact
     4381 gatcatcgac aacaccgttg actttccagc accatttgga ccgataaaag cagtcaactt
     4441 cttttcagga atcgttaact gtacatcttt aaccactgat tttccatggt acagtttatt
     4501 gaccttttgt aaatcaatca taggatactc ttcctttcgc gaatcaattt tgtgacaaaa
     4561 taaattcctc cgacaaattc aacgacgaca ctcactgttg tattccagcc gaaaatctgc
     4621 tctactgcga gctgtcctcc tgtcagaaac agcatagcta ccagaaagct tccgataaat
     4681 agctgaccat gacgataagt agaaaagaca cgataactga tatttgcgac aataaaccct
     4741 aaaaaagtaa ctggacccac aagagccgtt gatgtccctg tcaaaagact gacacaacat
     4801 aaaatcaaaa attcaaaacg atctgtgtct atcccgaggt ttactgcttg ttcatttccg
     4861 agatggaaaa cgtctagcac atgtcgatat cgaaataaca ggtaccagca gccgataatg
     4921 atcaaagaag caggcaaaag atactgactc tggatattgc caaagcttgc aaataatctg
     4981 ccttgaagca aatcatattc attcggatcc atgatgactt gtaaaaaggt actgacacta
     5041 ccaaaaagcg tacctaaaat catccctgac atcagtaata aaaaaagatt cgctctcatt
     5101 tttttcaaaa gaaagaaaaa taacaataga ctcagcccga ccatcagccc aacgttcaat
     5161 aagaaaaaaa ctgtacctgt ctgctgaagc atcgtcactc ctccgataaa gaagaaaagg
     5221 accgtttgga caaggacata taacgactca agtcccaata ctgaaggagt caaaaactgg
     5281 ttatgcgtaa ttgtctgaaa gctgattgtg gcactgctga cagctagcga gacaaggata
     5341 aatgcaaaaa ttttcttact cctcaatgca catgcaaaat gccagtttcc atatgtatgg
     5401 atcgtcaagt acattcctgt aacaaataaa acaagaacaa gcataccaat aaaaatagat
     5461 ggcttttttt taagcatatc gtcgtcccct tatcagaaga taaaggaaga tagccccacc
     5521 gatgattcca acgatcacac tgactggtat ttcataagga aaaatcaaca cgcgagcgac
     5581 aagatcgcaa aatactaaga acaaactacc tgctaaagca gttacgccaa ttgttttgtg
     5641 cacttgatct ccatatattc tagagacaag attcggaatg atcactccga taaaaggaat
     5701 gcttcctacc atgatcaaca tgactgcact agccaatgat actaagccaa tgcctaaaaa
     5761 ctgcatcttc tggtaatcta ttcccagatt tactgcaaac gattcgccca gaccaatgat
     5821 cgtaaatcgg taagcaaata gccaaaccaa gagcaacaat ggaacaacag catacaataa
     5881 ctcataattt cctcgtatca cagtcgcaaa attcccttga agccatgaag tcatattttg
     5941 taccaactgg aattgataag caaaaaaagt agcaactgaa ccaatgatat tccctaacat
     6001 gactccaatc aacggaagca tcaattgatt tttctggagg aacaatcgcg taagggataa
     6061 aaaaagcaat gttcctgcaa aagcaaagca aaatgctgtc aaggatcgga caatcaagga
     6121 tgcaccaggt aggaaaatca tagccactaa aatacctaaa cgcgcactat ccatcgtgcc
     6181 cgcagtcgtt ggtgaaacaa atttattttg ggtcaaatgt tgcatgatca acccacaaat
     6241 actactggtc gctcccacaa ggatcaaaca aatcgttcgt ggcaaacgag tcactagcaa
     6301 gatttgtaag ctttgcccat ctaactggag cagttctgac aattgtacat tcgatactcc
     6361 gatgaacaat gaaatactac ttaaaataac taataatgct actagtcgtc cgtagcgcat
     6421 ccaatccacc tttctaattg agaatgattt tcattcttat tttaagtgaa tcgttgaaca
     6481 aaagcaaccg ctttttcata tgttttaggt attattggga atatgctata atcgtaagaa
     6541 agacaaagag aagaaggagg gtatttttta tggcacaaga tgatgtaaaa agccatttgg
     6601 ataagggact ttatggtaca cctttagtga accctgaaga acagcataaa tatttaggga
     6661 cattcaggga acgctgctat cttagtatga ctgttgctga aatgatccaa ccaaaaaaca
     6721 aagaaaactt tttaaaagaa ctcaaaaaac atccagatgc ttccatactc ttgaatgggg
     6781 ctctacccct ttctgtccaa aaccaatata tccagctagc aacgaaaaac aatagccgtt
     6841 tcactgtagt caacgattac gtcactgcaa atcctgagga attcggattg ctcttaacag
     6901 caaaagaagc agtaaatgaa cctgtgattg atatcgaaaa aaaataccca gaagaaaact
     6961 cttcgccagc tgaaaaagaa aaaccaaaaa agaaaaaaag cttctgggat cgtttatttt
     7021 aaaacgaaaa aacacataaa tttttacatg caaaaaaagc ttttgatcag attgacatca
     7081 aataggacaa tctgtcaaaa gctttttctt ttaaaatact tcaggatata acaatttcaa
     7141 tacattcatc gtcaatcttc tgccttttcc tgcaaaagga taaacatgca tatgcatggc
     7201 tggattgaaa tttgcttcga tgatcccata tgctttttta tcagttgtag gatcgatttc
     7261 tttatctggt ataatcaaat cgataccact aatcttagct cctagtgctt ctaccgcaga
     7321 aacggcgatt tttttgtaag cttcagaaaa ttcatcagtc atatcgatcg aatcaccacc
     7381 tgtactgata tttgagttct cccttagata aacaatttga ttggcttggg gaactgattc
     7441 gatcgtcaac ccttgttctt tcaacatcaa ttgttctaat tcacctaatt ggatcaattc
     7501 taaaggtgca cgatgattcg ttccacgcaa agggtcacta tttttttctt caacaagttc
     7561 tttcactgtt cggatactgt caccaataac attagcaggg actcgcaaca tgatggcttg
     7621 gacttctccg tcgatcacaa agaaacgata ttccgttccc ggcataaatt cttctactaa
     7681 aaccgaactg tcttcacgaa aagcaatggc taaacctgct tgataatctt ccagactagc
     7741 tccttccttg aaaatcgtga tacctaaccc gtaattggtt gatttaggtt tgatcacaaa
     7801 tgcctgctcg gcaaatctcg gataagcttt taccgcttct tccatggatg aaaattctgc
     7861 gcctcctggt acccggaacc cagcttcttt taagactttt ttcgttactg ttttgttttc
     7921 catgataagt gggacgatat agctgtcctt acttgtcatg tttgcatttt tcacatattc
     7981 tacatggtct tggaattgca gacgcaaaaa ttgatccgac tcatctaata ctttgacttg
     8041 gacacctttt tggatggcat cgaacataaa tatctgagta gaaagttcca tttcgcgaaa
     8101 accggccaac tgatagggac gttcatggct ttctttataa tattgatgtc ccaatgccac
     8161 agcaacttct tgctgactcg atagctgtgc ttcttgatag agtttcgctg ctaacgtttg
     8221 ttcaggatga tccatttgag tcaatgcttc ctctactaaa taaagagaat ccaaccaatc
     8281 caattcaacc agcatttgct tcattccttc aagaatttct ctaccttctt gatgaaattc
     8341 tgtttgatct gatggttgtt ctagtgctac tttgttattt cgagtcgtac cttctgctac
     8401 ccattggtca cagtcttctt tttcttctgt ccataacatg tacatcagga ataattgtaa
     8461 gaaccgaact tgctctggat tgatacccaa tcttgcataa ggattcaaat cgatattccg
     8521 caattcaata taacgaacac ctgttgttgc taaatctgcg actttctttc cgcctcggaa
     8581 acgaagcggt gtataaaatt ctttctcctc cgaaagtttc ccttcttcga tcattcgctc
     8641 gatatctgct aaatactgtt tcatagaagc ataggaaact ttcacatttg gatgattcgt
     8701 atagcccagc gcactgttgc gaatactgcg aacaggttct tgcggatgtg attcatctaa
     8761 aaagtagttc ttctcactca ttggtgaagc accgaataaa taagtgatca tccagcgata
     8821 gcgcataaag tttctcgctg ttttcaaata aagttctgtt ttgaattcgg aaaaatcttg
     8881 aaattcttcc tgatggctga acaatgttct tagcaactca tcgccaaatt caaaattgaa
     8941 atgaataccg cttaccatct gttttcgctt cccgtattct tttgctaaat aacgtcgata
     9001 caagacatct tcgaaatttt ttaattttgc aataatgatc tcttcgtctt tttccggtaa
     9061 ggcaggtggc atacttaatg gccagatcat ctcttctttc ggtatagaac gagcagtcac
     9121 atcataaaca gcagcgagat actgaaataa ttcgggaata gaatcggtaa caggggtgat
     9181 catctctgtt tgtgtttcgc taaaatctgt ttggatatag gggtgatagg atcgatcgcc
     9241 aaagattgct ggatgatcgg tttttgctag atttcctgca agatcaaccc gctgtccttc
     9301 ccgttctata ccaaatcgag cttggtcgat aaaagggcgc gcattgacat gcaataataa
     9361 ttgcttaaaa ttcatcatta agtgacctcc aattcatatg aatctaatta taatcaaaaa
     9421 gtctaagaaa aagaacgaaa ttgtttgaga accgcttaca aataagtata aaaatgaagg
     9481 catcaaaaac acagctatgt taaaaacaat cattcaaaca aggagctgca acttttgtca
     9541 cagctcctgc tttttagaca tgggttattc ttcttttagt aatcctttga acaatccaac
     9601 gacaaaatca tttggatcaa acggctccaa gtcatcgatt ccttcaccaa gaccgaccaa
     9661 tttcactggt aaatgcaatt cattacggat agcaagtacg ataccgccct ttgctgtacc
     9721 atctaatttt gtcaaaacaa gaccggtcac atctgttgtt tctttgaatt gttttgcttg
     9781 aaccatcgcg ttttgaccag tggttgcatc taatacaaga agtgtttctt ggggtgcttc
     9841 tggtaattcc cgctggatta ctcgttttat tttttctaat tcgttcatca agttcacttt
     9901 attttgcagt cggcctgcag tatcaactag taaaacatct gcctgctctg tctttgctct
     9961 ttccaaagca tcgaatacga cagctgctgg atcgcctcct gcattgccac gaacaacttc
    10021 aacaccagcg cgttcgcccc agacaactaa ctggtcgatt gctccagcgc ggaaggtatc
    10081 tgctgctgcc atcaatactt ttttaccttc gtttttgaac tgatgggcaa gtttaccaat
    10141 acttgttgtt ttccctacac cattaacacc gacaaacaaa ataactgtta gtccgtcttc
    10201 ttggatattt agttcattta cttcattgat tccttccgct tcatagagat ccacaagttt
    10261 ctcgatgatc gcattttgga cttctgccga ttttttcgca tttctgagtt tcacttcttg
    10321 acgtaatgct tcggtgattc gtatcgctgt ttcaaaacct acatctgcac cgataagtgt
    10381 ttcttctaat tcttcaaaaa agtcttcatc gactgttcga aaattggcaa acaactcatt
    10441 catccgttca ccaaatgttt tacgcgtctt ttctaaaccc ttgtcgtact tctcctgtac
    10501 ttcaacttct tctgttttct cttcgccagt aaaagcacgc ttgattttat caaaaaatcc
    10561 catttgactc cccctactct aatacaaatt tttggatcac tttggctacg ccattttctt
    10621 cattgctggc tgtcacgaaa tctgctgctt ctttgacgaa aggcacagca ttctccatcg
    10681 ctacgcctag tccagcatat tggatcatcg gtaaatcatt ttcctcatca ccgatcgcca
    10741 tgatttcttc ttgtttcaaa ccaagatctt ttgccaataa agaaatacca taagcttttg
    10801 taacaccttt tggcataaat tccaaaagca tacttcttgt tttgatgatc tcatacattt
    10861 catggaattc tgctggtatt tctttgattt taggatctaa ttcttcttgg tcataagcga
    10921 ttactgcctt attaagcaca aattcatctg taatatcgct tatatccgct ggttggaatt
    10981 gcagcagctt attcaacaca ttgtacaagg attgcttcct tggggcacta ggcagctgta
    11041 aaaccacatt gtcagacaaa acatctagtg gcagatccaa ttgctgagcc agtttgtata
    11101 agcgttggat atctgatact tccatcactt tcttttccat gatttcacca gtatcatttt
    11161 tttgtaccaa accgccgttg aaagtgatgc tgtagtcacc ttcatctacc agtcctaatt
    11221 cttgcagata atgcgccatc gcagctaagg ggcgtcctgt acatagaacg atcttgaccc
    11281 cttgctgttt tgcttgtgct aatgcttgtt tattctcatc tgaaatcagc ttttgttcat
    11341 ttaataatgt accgtccaaa tcgattgcta ctaatttgat cattttcgtt cctacacttt
    11401 cgtttcgttg attttcgcct cttcattgat atcttccatc cgtacagaaa cgatttttga
    11461 tacaccggat tcctgcatcg tcactccgta cagtacatct gctgcgacca tcgttccttt
    11521 gcggtgtgtg actacgataa attgtgtgtc atcttggaaa tcgctcaagt aacgaccaaa
    11581 acgtttcacg ttggcttcat ctaacgctgc ttctacctca tctaagatac aaaacggaac
    11641 aggacagaca cggataatgg aaaagagcaa cgcgatggct gtaagtgctc gttctcctcc
    11701 agaaagcaaa cttagacttt gcagtttttt gccaggaggt tgtacttcaa tctcaatacc
    11761 tgttttcagc aaatcagttg gttccgtcag tactaattca gctttaccgc cgccaaacat
    11821 atttggaaag acaattttga attcttgacg gatagcttca aatacttctt tgaatcttgt
    11881 ccgcacttca tcatccatct catccatcgt ttcaaacaat tggtttttcg ctgctaacag
    11941 atcatctcgc tgtgttgcta agaatgtatg tctttcactg acttgttcgt attgttcgat
    12001 tgaatttaag tttactggtc ccagtttttc aatctgttct tttaaggatg aaacctttgt
    12061 tctactgtct tcgatatcgg ttgtttcttg atagtcttgg gaagctttct caaatgtcag
    12121 ctgatattct gactgcagat aggtcaaatg attatctaaa atcatttcag ctcggtcttt
    12181 ttggacttct aatttggatt gttccgacag tcgtgctttt tgctcacgat tacgctctgc
    12241 caagactgct tcaagcttat cgatctcctt ttgccttcta tctcgctgct ctttggcttt
    12301 tgccaactcg gcttttaatg tttctcgctg agcagataat tcgttaattt gtttttccaa
    12361 actttcttct gtgacttcat gatcagaaaa gtctgctgtc aatgtcgcca actgcttttc
    12421 tatcgcttct tgacgttcgg ttgcctctgc tttttggact cgggcaccgc ggagctggat
    12481 ctgcagatga ttaaactgct ctttcaagac agcaagatct gcttgttctt gtgctttttg
    12541 actttgtact tgtgctcttc tggcttccat ctggtcgctt tcttgactta acgatttgat
    12601 ttcttcgtcg attttttgtc gttgcgattc aagatctgtt tgtttgtctt tcaattcgtt
    12661 cgtttgcttt tcgtaatctt cgataaactg ctgcagttca cgtgtctcaa aagttgagat
    12721 ttgcttttct ttttcaaaac gttcaagttc atttatgatg ttttgtagct gatttgtcgc
    12781 ttcttgttct tcaaaacgta attgttcgcc tcgtgtacgc aaaacttctt gttcttcggc
    12841 taaacgagct gtttcttgtt gcagctcctg aacttttttt tcttgtgctt ggagttgttt
    12901 atctgcttct tcaaattcac tagtcaactg tttcaattct tgattttgta caaacaaact
    12961 gccttggttt cctcgtttat tcgctccacc tgtcatggat cctccggcat tcatcacatc
    13021 accttctaag gaaaccactc gatattgata gcggatcgtt tgcgcgattg cattggcact
    13081 agttaagtct ttggctaaaa ggatcgttcc tagcaggttt tgaaccacag tttggatttg
    13141 atcgggataa ctgacttgtt cactggcaat ccctataaac ccttctacag ctgctgcttg
    13201 tgtcaatata tgagccggta attgtcttgg tttgattgtc gtcagtggaa ggaatgttgc
    13261 tcttcctcct ctttgctgtt tcaaatacgt gatggcttgc cgagcatctt tttcattttc
    13321 aacgatgaca tgctgggctg ccccacctaa agctgcttcg atagctaacg tgaaatctgc
    13381 aggaacatcg atcagttcag ccactgctcc gacaataccc gaaagctgct gtttatgctg
    13441 caagaccaat cgaacccctt ggtaaaaacc aaaatagttt tcttggattt cttgaaggct
    13501 tttcttacga gcacgtagct gctggacttg attcattaat tgatacattt taggctgttc
    13561 ttttgctaat gcttcttgga actttttccc gttttgttgg atcatttcta acttctcttt
    13621 tgtttcagtt aaagatgatt ttagctgcgc ctgcttttgt gtcaattctt ctttttgtaa
    13681 gatcaatcgg tctactgatg cttctacttc cgattgcttg gctaacgtct gcttgctttt
    13741 tgctgtttct tgtatatatt gacgttctag atacttcagt tcgtttccta cagctgcttg
    13801 ttcttgcatc aaatcaacat attgatctct taattctgcc aataattctt tcgttgattt
    13861 ttggtatttt tctaattctt gctgtgtttt tatgagattt gcttcagctt tttggatctc
    13921 tgtttctttt tctgctgctg ctttcatcaa gctttcttga agcttttcaa aatgtttaac
    13981 ctttttttgt gcttctgcta atgaagtttg atattcttgc gagctttttt gtgtatgctt
    14041 tgtccgctcc tgcaaaacat ctttttgtcc ttctgtctgc ttcagttttt ccgaaagatc
    14101 taataatact tgctgatttt tttcgatcag acgatcggct tgcgcatttt ctttacgctg
    14161 cttcgccaaa atggattctt gttcttggat cgactcagat agtttgccta attctagatt
    14221 gaatttcgca agctgtgctt gtttgttgtc ccaatctttt tttgctgtct tgatttcagc
    14281 aaccatcaaa gagacatcgg tttgagtcag tgtttctttt agccgtaaaa actcctttgc
    14341 tgcctcactc tgggcggcca aaggagttaa ctgttcttcc aattcgtgga tgatgtcttg
    14401 gacgcggctg aggttgtctt ctgtttcaaa aagcttctgt tctgctttct ttttccgctg
    14461 cttgtatttc aagacaccag ctgcttcttc aaagatccca cgacggtctt ccggtttact
    14521 actgaaaatc gcttctactt ttccttgaga aatgattgag aacgattctt ttcctaatcc
    14581 agaatctaag aacaattctt ggatatcttt taatctgcag ctttgtttat tgatgaaaaa
    14641 ctcgctttcc ccagtccgtc gataacggcg ggttacactg atctcattgt actccaatgg
    14701 cagataatga tcactattgt ctaaaatcac tgtgacttct gcaatattca gctgcttacg
    14761 ggtatcggaa ccggcaaaga tgatatccgg catttttccg cctcgcagac ttttagcaga
    14821 ttgttctcct aatacccagc ggatagcctc tgtaatattg ctttttccgc tgccatttgg
    14881 tccaaccact gctgtgacgc tattttcaaa atcaatgact gtcttgtctg caaatgattt
    14941 aaaaccggct atttcaattc gtttcaaata caaagctttc cctcacttac ttttacagtg
    15001 ctgccaatgc attttccgcc gcagcttgtt ctgctaattt tttcgatttc ccttgtccag
    15061 tgccaatcaa ttgatcatct acataaactt cgatccaaaa tactcgttca tgagctggac
    15121 cttcttcatt gatcaatcgg tattcgattg atacatcacc tgatttttgc aagacttctt
    15181 gtagttttgt tttatgatcc atctcatgtg aaaaagcacc tgctttgact ttaggaaaaa
    15241 tcactttttc gatgaatgca tgggtcgtgt cgaatccctg gtcaagatat aacgcgccta
    15301 aaaaagcttc gaataggtcg caaagcaatg ctggtcgcgt acgtcctcct gaattctctt
    15361 ctcccttgcc caacaaaaca tattgatcaa agtgacattc tttggcaaat ttcgacaagc
    15421 tgtcttcgcg aacgatcgca gctcgtgttt ttgtcaattt tccttctggc aaatgaggat
    15481 ataaacggaa taaatactga gaaaccatca gttctaaaac ggcatctcct aaaaattcaa
    15541 gtcgctcatt atccgataat tgcagattgc gatgctcatt cacataggat gaatgggtaa
    15601 aagcttgttc aagcaaattt agatcgtgaa aaacgatgtt atagttttct tttagttctt
    15661 ttgtcagctg gttgtccatt ttccacattc cttttatgga tattttttcg atacttcctt
    15721 attatactgg ttttttgtca aatttgaaat ggttcggtca aaaggtaagt aaagctttaa
    15781 taatcctagt gattgacgag aagttgtgaa aaattcgttt agtttcgagt atgaagaaaa
    15841 aattttgtga aaatggcttt ccatattttt gcataaattt gacttaatac cgagaaactg
    15901 gactttgaac accgtttatt ggagaagtca tgaaatcagc gccttgacct gaatattaga
    15961 gaaataaaca gaaaaatatc aaaaaaccga aaaaggacat cgcccttttt cggtcatttt
    16021 tagtgattat gaacgtgaat ctgctgtaac agaaacattt gcccatgggt ttggtacatc
    16081 ataagaccaa tcccagtctt tgacacggtc gttgactggc aatacttcat tacggaacaa
    16141 cgttggaatc gcaaatgctt cttcaaatgc atattgttgc catttttgat atgcttcttt
    16201 ttggtactct tcatcaaatg ctttgcttga actgatatcg ttgatcaatt ttgtattttc
    16261 ttctgattca taacgagtgt agttgaacgc agcatttggt ccccatagtc cacttggatt
    16321 tggatcagtt cctgtattcc aagcagcttg gtaaacatca atttcaggat catcgttttc
    16381 taatttatca tagaaagaat tgaattcgat cagacgacct gttgtgtatt ggacatccaa
    16441 accaatttct ttccattgtt ggatatagta atctgccaat ggttgcgctg tttccccacc
    16501 ggacatcgaa gcaaagttga ttgttagttt atttccatct ttgtcttctc ttaaaccatc
    16561 gtcatccaca tctttgtagc cagcatcatc taatagtttt ttcgctttgt ctagatcttg
    16621 tgtgaatcct ttcatctcat catcatggta tgactggaat actggaggaa tcaatgaagt
    16681 cgcattgctt ctcaaacctg catagaaacg ttcacctact gcattattat ctaatgcata
    16741 gcccattgct tgacgtaatg atttatcagc catttttgaa tctggattgt attccacact
    16801 ctttgtatct gcattccatt tacctaactt gaatcctaga taagtataag aagtttgttc
    16861 acggcctaag tttgtatagc cagcaatttc tttataggta tcgtaagtat ctgttggcat
    16921 ttggaaaatc atatcatata atttagagtt caatgcttca gttgcacttg ccatcggtac
    16981 agatttcatc gtgatctttt tcaatttagg cgtaccattc cagtagtgct cgtttggcaa
    17041 gtattctact gattctcctg caacgatatt actcatgtaa taagggccaa aagtcactgg
    17101 atttttacgt acttgatcgc ttgattccat atctttgatt gctacacctt ctaacgtatg
    17161 ttttggtgct gcatatgacc agataccacc acccgattga agcatgcttg ggtttacttc
    17221 tttatattcg atttcaactg ttttgtcgtc tatttttttg attccggaga ttgtgtcggc
    17281 acttccatca tgatattctt ccatacctac gatgttacgg aaagtgtcgt cataacggat
    17341 accagtgtaa tctttattcc caatgatttc gtaagggaaa atcacatcgt ccgccgttac
    17401 atcttcacca tctgaccatt tgacgttgtc ttttactttg attgtcgctt ttttcgtatc
    17461 ttcatctaga tcaagcgttg cagctccgtc gtctgtgatt ctgaaatcgt catcgtttgc
    17521 aaatagcggt tcatgagaag gagccataaa agctgcatca tatgaatctt ggtaaaactc
    17581 ccactggaac aatcctttaa actgactgtc cgttgcgacc gcagcttcta attcgccgtc
    17641 ttcgattgca tcatcattat tttttgttgc aattggaaaa gttaattcct ctttgttatt
    17701 gccgttgcct ccagagttgt ttccagaggt atctgtacct ccgcccccgc atgctgcaag
    17761 aacgacagca gacatcagcg ctgcaaatcc aaaaatcgtt ttcttcattc ctatttcccc
    17821 cttcgcttct atactagcct aaccgttggc gcgcatctgc agaacgcttg aatgcttgtc
    17881 caacataatt gatactcaac atcaaaacta aaataaggat tgatgcgggt aaccagatcc
    17941 attgccgatt cactaagact tctccgttac ttgcataacc gatcaatgta cctaaactag
    18001 gtacatttgc cggcaagccg aaacctaaga aagtcaaagt tgtctcgata ccgatgtttg
    18061 ccgcaaagtt catcgtcaaa ttagtaatga ttaatgaact tagattcggc atgatttcgc
    18121 ggaacatgat tttaaaatca ttggttccca ttgtttttga ggcactgaca taatctcttc
    18181 ttgcttcaga taatgtcttg cttcggaata atcgggcttt agctacccaa taaaatgcac
    18241 tcatgatgaa tataaaggac cagacattgt atctggaaat aatcgatacg aagacgataa
    18301 tgatcagcat gatcggtaga atcatgataa aatcaacgat ccgcatcaag atgttgtcaa
    18361 tgatccctcc gtagtagcca gagatgatcc ctaatccaac cccgatgatc gaagtaagga
    18421 tcgtgatcgc aaatccgatc gtaacagagt ttctagcacc tatgatcaat tgtcctaata
    18481 catcacgtcc gccttcatct gctcccagaa tgaacttttg tccttgtgtc gaaactgttc
    18541 ctggtgcagc gtatttgtcg aagatactaa catacatcac tttgtcttga tcggtcagca
    18601 tcgcaccgat aaagatcact aataataaaa ccactagcaa acctaatgaa aaaatagcaa
    18661 ttttatcttt tttaaattct cgagcaatca ttcgtatccc cataggagga atactttctt
    18721 gaactgctgt attgtttttt tcactcatcg atccattctc ctttctgatt ggttttattg
    18781 aatccgaata cgcgggtcaa cgatactcat gatgatatct gaaagtaatg tccccactag
    18841 cgtcgcgatt cctaaaatca atactaagga tgtgatcacg gtatagtccc gttggccgat
    18901 ggaatcaata aatagttttc cgactcccgg ataaccaaaa atcttttcga taactacaga
    18961 accagcaatc aacgaagtga tttcataccc catttgagaa gccatcggca acgctgcatt
    19021 tcggaaaata tgtcgactga atactttatt cgtcggtacc cctttggaac gggctgttct
    19081 gacaaaatcg agcgatttcg aatcgattac ttcacttcgc agatattgga ttgtgacggc
    19141 agtcgccaaa aatgcttggg taattgatgg taacagaata tatttcaaac ggtctatcca
    19201 ttgagtgata aatccacctt gcaaacctag tgtttgtgat ccacttgttg ggaaccagcc
    19261 taaacgataa ccaaaaacaa atagcatgat caagccgaag ataaataaag gaacagcaaa
    19321 actaaagaag ttgtagatta cgacaatctt atccaagatt gaattttgat accggccagc
    19381 aagcatcccc agaggcacag caatcaaata agtaaggaca actgtcaaga tcgatagata
    19441 taaagtgttg atgatccgtt cgccgatcaa gtcagcaaca gagcgtttgt ataagaaact
    19501 ttgaccaaaa tcgccttgca aagcatttcc gatccaacgg aagtactgga cataccatgg
    19561 gtcattcaag ccagctgctt gtcgcatctg ttcgatcact gccggatcct gatttggatt
    19621 gatcaaaccg gtaaatggat cccccggcat cgcttgggct aataagaaga tcagaacact
    19681 taaaataata acttgcggga tcatcaataa aacacgtcgc agaatcgttt tccacattag
    19741 cttgcacctc catctttcaa cgccactttg tgtgtagttg tgatcgtacg caaatcgtag
    19801 actcgaccag tcgcatcata gtattctttt tggttttgga tatactcttg ttctactctt
    19861 cgtcgatttt ctttgtggct ttccctattt tctacatcga tttgcggaat agctgaaagc
    19921 agacgtttcg tatagatatg tcgcgggtca ttataaatgt cttctcttgt accgatttct
    19981 acaaatcgac ctttgtacat aattgcgata ttgtcgcaca tgtgttttac tacacctaaa
    20041 tcatgtgaaa tgaataaata gctgaggccg tattcttgct ggattcgttt catgaaattc
    20101 aatacttgcg cttgaacaga tagatccaga gcagatacag gttcatcggc tacgatcagt
    20161 tttggattgg tagcaacagc acgggctact cctagacgtt gacgttgtcc gcctgaaaat
    20221 tcatgaggat atttatatag cgcatcttcc ggcatcccaa cgatatctag cagtcctttt
    20281 acctttttct tttcttcttg atcgcttaac cgttcaaaat ttcggatggg ttcagcaatg
    20341 atatccaaca ctcgcttttt aggattcaaa ctggacattg aatcttggaa gatcatctgc
    20401 acatccttgt tataacccat ttttttgcgg ttgcttcgct tcgttacatc ttttccttca
    20461 tacatgattt gtccggctgt taccttttct aatcccacaa cggcttttcc cgtagtagat
    20521 tttccagagc cagactctcc cactaaacca tatgtctttc ctttttcgat aataaaatcc
    20581 acaccatcta cagcatatac atgatccgtt actcgattga agaatccact gcgaataggg
    20641 taatgaactt tcaggtcttt gattgtgatt aattctgtca tctacacctc tcctttttcg
    20701 tctctaaagt ggaaatgctt atagcaggag caacgtacca agtggttcgg tgcgacttca
    20761 tgaaggatag gctcttcttc atgatcgctt gctggtatcc atggaatacg tggtgcaaac
    20821 cgacaacctt tacgaggcat gtttttcaga gaaggaacga caccttcgat cacatggagt
    20881 tctgcatcat gatttccttc ttgtggtata gagttcagta aagagcgtgt ataaggatgc
    20941 ttaggatgat caaacagttc ttttacacct gctacttcaa cgaactgtcc gccatacatc
    21001 actgccactc gatcagccat ttctgctacg actcctaagt catgagtgat caagatgatc
    21061 cctgtttttg tttcttcctg aaggtctttc agtaaatcaa gaatctgtgc ttggatggtt
    21121 acatctaggg ctgtcgtcgg ttcatctgca atgacgattg gaggtttgca ggcgattgcg
    21181 attgcgatga tgacacgttg tctcataccg cctgatagtt catggggata ttggcgtcca
    21241 actctcgcag gattaggaat ccctacttgt tctagcaatt ctagtgcacg agcttgacgc
    21301 tgttctgcat tcatctttgt gtgataggaa agtccttctt tgatctggtc ttcgattctc
    21361 atgagaggat ttaatgcaga caacggatct tggaaaatca ttccgatatc atttccgcgg
    21421 attttattat agagcgtttc gttcaggtcg attaaattca gatcgttata taaaatctca
    21481 cctgtaattt ttgtgttatt aggatcaagt aatcccataa tcgtagtagc caaggtactt
    21541 ttcccgcacc cagattcccc aacgattgct aaaatctcgt ttttgtctaa agtaaatgaa
    21601 acgtcatcta ctgcatcgta atagtcatct ttgagtcgga atcctgtatg taggttctga
    21661 acttctaata attggttatc ggacaatcga atacccctct ctgcttccta aatggaagtt
    21721 tttcttaata aaaaaggaca ttacacagaa taaatcgttt tataacaaag gttattctta
    21781 tctttgtgta atgaattatt aataattata tagaaaaccg ctttactttg caacataatt
    21841 tctgtttatc gccagaatta tcagaaaaat gacttttacg tgtcaaaaag attaaaaaaa
    21901 gaaggataaa aagctgcatg cagcttttta tccttctttg ct
//
LOCUS       DAXLPY010000048        21213 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.048, whole genome shotgun sequence.
ACCESSION   DAXLPY010000048 DAXLPY010000000
VERSION     DAXLPY010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.048"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(565..1590)
                     /locus_tag="ACF3UF_001859"
     CDS             complement(565..1590)
                     /locus_tag="ACF3UF_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3671960.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            1865..3550
                     /locus_tag="ACF3UF_001860"
     CDS             1865..3550
                     /locus_tag="ACF3UF_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFD3671961.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            3564..4847
                     /locus_tag="ACF3UF_001861"
     CDS             3564..4847
                     /locus_tag="ACF3UF_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3671962.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            4917..5786
                     /locus_tag="ACF3UF_001862"
     CDS             4917..5786
                     /locus_tag="ACF3UF_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671963.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            5783..6619
                     /locus_tag="ACF3UF_001863"
     CDS             5783..6619
                     /locus_tag="ACF3UF_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3671964.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KVRSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            6645..7712
                     /locus_tag="ACF3UF_001864"
     CDS             6645..7712
                     /locus_tag="ACF3UF_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFD3671965.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            7709..8536
                     /locus_tag="ACF3UF_001865"
     CDS             7709..8536
                     /locus_tag="ACF3UF_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFD3671966.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            8581..9606
                     /locus_tag="ACF3UF_001866"
     CDS             8581..9606
                     /locus_tag="ACF3UF_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3671967.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            9603..11786
                     /locus_tag="ACF3UF_001867"
     CDS             9603..11786
                     /locus_tag="ACF3UF_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFD3671968.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            11786..12916
                     /locus_tag="ACF3UF_001868"
     CDS             11786..12916
                     /locus_tag="ACF3UF_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFD3671969.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            12913..13590
                     /gene="pgmB"
                     /locus_tag="ACF3UF_001869"
     CDS             12913..13590
                     /gene="pgmB"
                     /locus_tag="ACF3UF_001869"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFD3671970.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            13674..14201
                     /gene="msrA"
                     /locus_tag="ACF3UF_001870"
     CDS             13674..14201
                     /gene="msrA"
                     /locus_tag="ACF3UF_001870"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFD3671971.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14402..15088)
                     /locus_tag="ACF3UF_001871"
     CDS             complement(14402..15088)
                     /locus_tag="ACF3UF_001871"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFD3671972.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            15168..16706
                     /locus_tag="ACF3UF_001872"
     CDS             15168..16706
                     /locus_tag="ACF3UF_001872"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFD3671973.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16826..17293
                     /locus_tag="ACF3UF_001873"
     CDS             16826..17293
                     /locus_tag="ACF3UF_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFD3671974.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            17827..18255
                     /gene="rplM"
                     /locus_tag="ACF3UF_001874"
     CDS             17827..18255
                     /gene="rplM"
                     /locus_tag="ACF3UF_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFD3671975.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            18271..18663
                     /gene="rpsI"
                     /locus_tag="ACF3UF_001875"
     CDS             18271..18663
                     /gene="rpsI"
                     /locus_tag="ACF3UF_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFD3671976.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(18751..19977)
                     /locus_tag="ACF3UF_001876"
     CDS             complement(18751..19977)
                     /locus_tag="ACF3UF_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3671977.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(20049..20351)
                     /locus_tag="ACF3UF_001877"
     CDS             complement(20049..20351)
                     /locus_tag="ACF3UF_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3671978.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNTFKIT"
     gene            20899..>21213
                     /locus_tag="ACF3UF_001878"
     CDS             20899..>21213
                     /locus_tag="ACF3UF_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3671979.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQR"
BASE COUNT         6871 a         3783 c         4397 g         6162 t
ORIGIN      
        1 ttgtcacaac ctcttttttg gtttgtctaa aataatttgt ctaactagaa gaaaagtggg
       61 aaaggatctt aacaacatcg gttcgtatcc aattaaggta tcggaacgat catcttccaa
      121 gagaagtcaa tcaacaaaag taaagataga tcattttttg aatgcaaaat aaattgatgg
      181 gaagatagag cggttatttt taatattttg ctagctatta ttgaataatt cctcgaataa
      241 aacaaaacca gtagacatgt ctgttattct atttatgttt tagagataag tatccccaaa
      301 taacatggat tgaaataagg gtaaatgtgt ttaaaaaaac gaactataaa aacttataca
      361 caacgtggtt aaaaatagtt ttttcttccc tgtggaaaaa atagtttaac acaaacatta
      421 tagttatcca cagctatcta aaacagatgg aaaataagaa aaattcgcta aaataccggg
      481 agggggtaac gagggatgag tgattgaaaa aagaacagag taactgactt atcctcagtg
      541 tttctgttct tttataattc tgttctacat ttcttgttgt tggatcgaat ctgtgagagt
      601 aatctcggtt gaaagaatga ttcttttttc ttcagggtat tggtggtgga ttagttggaa
      661 taaaagttct gtggctttga ttcctaactg atttgtcgga atgtctatcc gagtcaactg
      721 tggcgaaaat agggaggaca ataagggatc actgaatcct gcgatcgaaa gatcatcagg
      781 tatctgcttt ccagattgtt ctgccacttt gtaaatactc aatgatttta atgcatcggt
      841 agaaaaaatc gcagttggtc tttctcgtag cttcattaaa tcattcattg ctgccatgct
      901 atcttctaag cgaaagccgc cgtctataat ccattcatta cggatatcta ggtggtgatc
      961 aaataagcat tgacggtaac cattgagacg atcattggat acataaactt ctgtcggagc
     1021 atggagacag ccgatatgac ggtgtccatt cttgatcagt gtttccacca aatcgtaact
     1081 atcctggaaa ttatccgtgt ccactgagta gatgttcgtg tagtcgtttc cgacttttcc
     1141 gattaccaca ataggaatat tgtattgatc caattcaaaa agaagtgttt catccatcgt
     1201 agagcttaaa ataataattc ctcggatcat tttttcttgg atctttttcg cgcatttttc
     1261 tagctcttct tctggtgttt ttgccgtttg tagaatcaag tcgaagttat tttgttcaga
     1321 aacggcagaa atggattgaa taacatctga aaaaaaagga ttgccatagg tcgtatgaga
     1381 agtacgatga gataatgcta gaatcgcgtc aaaaccattt cctgacagtc ctcttgcaat
     1441 tttgctcggt tcataattca attctttgat tgcttgaagt acacttgctt ttgctttatc
     1501 agagatattt ggctggttat ttaatactct ggagacagtt gattttgaga cattagcttt
     1561 tttcgcaatg tcataaatag taggtttcaa ttttatatgc acctcctttt tgggagcgtt
     1621 ttagaataat tccatagtac aatagacatt cttttttgtc tatgattttg aaaatttagg
     1681 aatagcttgc atgatcatga gagaccatat ttttttaaga agctattaat tattgataca
     1741 taagctttct tatttgtatt tttgtgtata tcaaaattat ttaaaaaaat gctattgaca
     1801 gtaagcgttt tccataatat gatcaaatcg ttgggaacgc tcccaaaaaa gaaaggggaa
     1861 tccgatgtat acaaaacttt tacaagcgat ttatcgcgac tcagatttgt ctgagaaaac
     1921 cgcctctatg attgaacaaa aagtcagtgt ttatcagcag aagaaaggcc aggcaggcaa
     1981 actgcattgg gacgaagaag atattttctt gattacttat ggggatcaat tttttgaaga
     2041 gcagcaacca actttgcgta catttaagaa attttatcaa aagtatttgg cagatacatt
     2101 tagagttgta catttcttgc catttttccc atatacatct gatgatggtt tctccgttgt
     2161 aaattatcag gcaatcaacg accgtttggg cacatgggaa gatatagaag aaatgagaag
     2221 cgaaacacgg ttaatgttcg actttgtctg caatcatatg tctgccgaaa gtacttggtt
     2281 tcaggaatat ttaaacttga atgatacgta caaagatttt tttattgatt tgccactgga
     2341 tacagataca agcagcgtga ctagaccaag gaccagcccg ttacttacaa cgttcattga
     2401 caaaaacggg aaagaaaaac acgtatggac gacttttagc gaagatcaag tagacttgaa
     2461 ttttaaaaat ccagaagttt tattgaaaat gatcgatatt cttttgtttt acttagaaaa
     2521 aggcgcttca tttattcgct tggacgctgt gggattttta tggaaagaac taggaacttc
     2581 ttgtatacac ctgccagaaa cgcataaaat catccaatta ttccgtgcaa tcgctgatga
     2641 agcagctcca ggaacggtat tgatcactga gacaaatgtg ccacacaaag ataatatcag
     2701 ttattttggg aatggcgaga atgaagcaca gatggtctat cagttttcgc taccaccttt
     2761 gacccttcaa gcgattcgtt cgggtaatac aagtaagttg aaagaatggt taaaaaccat
     2821 cgatttcgca tcgaaaaaaa caactttttt taatttttta gcctcccatg acggtatcgg
     2881 attgaatccg gtacgaggta ttctgccgga aaaaacgatc cttgaattag tggaacagct
     2941 gaagaaagag ggtgcccgag taaactacaa gaaaaaccca gatggaacga ccagtccata
     3001 tgagataaac gctacgtatc tagatgcgtt aagttctcca acagatacga cggaatggag
     3061 aagcaaacgc tttttagctg ctcattcatt tttggtaacg ttaccaggcg tgccggcaat
     3121 ttatattcaa agtgtgctgg gaagtcgaaa tgattacaaa ggcgtagaaa aaacaggaga
     3181 gaatcgaaaa atcaatcggc aaaaattttt gttagcagat attgagaaag agttgcagac
     3241 agatccatta agaacagcag tatatggtga attgacccag atgctatcta ttcgaaaaaa
     3301 agaaaaagcc ttccatccga atagtttgat ttacttactg gactcagcag attcttttat
     3361 cagttttatt cgcgaagcga aggaagagaa agtcttagtt atccataatt tttccaatca
     3421 atcagcaggt tatcttttac caaaaggaga ttacctagac ctgttttctg gacaaattat
     3481 ccattgcagt caagaacgaa agttgatatt ccagccgtat gaatatatgt ggctgaaaat
     3541 aataaaataa gaggtggaaa aaaatgaaaa aaattattgt tactacctgt ctgctagcta
     3601 ctggatttct tcttactgct tgtggtgaaa gtcaaagctc taacgaatca caacagacaa
     3661 cgattcaatt catgcactct tctgtcgaac aggaacgatt aagtgtgatc aatgaactgg
     3721 ttgctgattt tgaaaaagaa aatccagaca tcaaaatcaa gcaagtgccg gtagaagaat
     3781 cagcgttcaa tacaaaaatc gttacgttag ctcgttccgg taaattacca gaagtaatgg
     3841 aagtcagtca ggattttgct aaagtgatgg ataaagatga actgattgat cagacggcag
     3901 tccaaaacgt tatcgaggaa gctggagaag ataattatta tgacggagcc aaaaaccttg
     3961 ttcgttcaga agatggaaaa agctatattg ctgcaccaat tagcggctgg gttcaaggta
     4021 tttggtatga caaagaaaaa ttatcagaag ctggtttttc agaaccagaa aattgggatg
     4081 atattttaaa aattgctcaa catttcacag ataaagagaa taaacaatat ggaattgcta
     4141 tgcctactgc tgaaggaaca atgagtgagc aagcgttctc tcaatttgct ttgtcaaatg
     4201 gagcaaatgt tttggatgat gaaggcgagg taacgatcga tacggaaaag atgagagaag
     4261 cattgtcgtt ttatcaaaac ttatcccaat acacgatgcc aggctctaat gatgtgacag
     4321 aaatcaaaga tgctttcatg aatggaacag caccaatggc aatctattca acttacattt
     4381 tgccttctgt ttatgaagcg gggaactcag aaaatatcgg ttttgctatc ccaacacaaa
     4441 aagatcaagc tgtctatggc acagtatctg gattgacgat ttcttctggt ctagacgaga
     4501 aacaaaaaga ggctgctgaa gcattcacag ctttcttatc tcaaccgaaa aacatggaaa
     4561 agtgggtctt gatgtctcct ggtggtgctc aaccagtgaa taaacaagta gtcgaactgg
     4621 atggttacaa agaaaatgaa gtcatcaagt cttttggcga gctgccatct gagattgcta
     4681 gtgcttttga tgaagtacaa gtctttggac tagtcgggga aaagaatttc acgaaaatgg
     4741 gagatatcac aagctcaggt gtgatcggaa aagcagtgaa ccaagtaact gtcggaaacg
     4801 aagatgtcga tcaagcttta gctgacgcac aaaaaaatac gaaataacaa gaagttctgc
     4861 caatggtgtt cgaaaaaagt agatagctat tggcagatta tcagggggag gtttcaatga
     4921 atcgtccaag gaaacattct gacttaaaat tagccatggg acttttagca ccaagcatgc
     4981 ttttattagc tgttttagtg ctgattccaa tgctttccaa tattcagatc agttttttcg
     5041 atatgccgct gaatcctaac tcagacgccg tttttatcgg attaagcaat tatcttgaaa
     5101 ttttaagtga tagtgaattt tatcgttctt taggtttaac agttgcttac acattcttag
     5161 ttgtagcagg cagtacagct ttaggattag ccgtagctat tttgcttaac cgcaagttca
     5221 gatttaggaa aacggtgcgt tcactgattt tattaagtta tgttacgcca tctatttctt
     5281 tgatttttgc ttggaaatat atgttcaata atagttatgg aatcgtcaat gatctgttag
     5341 tagataggtt gcagcttttc aacgaagcac cgctgtggtt cgaccagcca gttgctagct
     5401 tctttatggt cgttttgttt gctatctgga gatactatcc gtatgcgttt atttcatttt
     5461 tggctatttt gcaaacagtc gacaaaacgc tttatgaagc agctgaaatg gacggtgcaa
     5521 atgcttggca gaagttcaag atcgtgacac tgccggcaat caaaccagta ctagcaactg
     5581 tgattgtttt acgatctatc tggatgttct atatgtttac agatgtctat ctactgacga
     5641 ataaagtcaa tatcttaggc gtttatttgt atcagacagc ctttgcgttc aatgatcttg
     5701 gaaaagcagc agctatatcg attctattgt tcatcattat tgcagcggtc gtcttgctct
     5761 cacgaaagaa ggtggacttg aaatgaaaaa taaaaagagc aggaaaatct tattttacgc
     5821 gacgattttg ttgctattag ctgtcaattt gtttccattt ttgatcatgc tgatgacatc
     5881 attcaaggat tcacaagaag caattgcaac gacacaaact atttttccga aagaatggac
     5941 ttttgaacat tatcaggata ttttcaatgc tgagattttt ccattcatca tgtatttcaa
     6001 aaatagttta gtgatctcct tgatagcctc cgtaactgca gtagtgattg ggatcagcgg
     6061 ggcatacgct ttgtcaaaac tacgcttcaa agttcgctcg aaaatcaatg ctagctttta
     6121 caccgtttat atgttttccg gtattttgat cgttgttcca ttatttaaaa tcatttccgg
     6181 tctaggtttg tatgatacca atacagcact gattatcacg atggtcgttc aaacacttcc
     6241 tactgcgata ttcatgctaa aaagttattt tgacacgatt ccgactgata ttgaagaagc
     6301 agcaatgatc gatggtctta gccggatcca gatcattatt cggatcatta taccattggc
     6361 tatttctgga atcatttctg tcttcgttta ttgctttatg gtttcgtgga atgattattt
     6421 atttgcttcg attttcctgt cgacctccga aaaatttact ttaccaatcg gtttgaacac
     6481 attattcagt acaccagact acatttgggg acgaatgatg gccgcttcat tggtgaccgc
     6541 tttaccagtc atcattatgt atgcgttatc tgaacgattt attaaaggtg atttagtcga
     6601 aggcggcgta aaaggataaa aagaaaagaa agaggaaaga aaagatgaaa aaattagttg
     6661 cattagaacc aagaatagcc ggattcaaag attacgaaga ccgtgagatc gaaaagaacg
     6721 aagtacgtat ccgagtaatt ttcgctactc caaaaccagg aacagaaatt gtcgacttta
     6781 gaggattaag tccatttatc gatgaagaat tttcagaaga atggcgccta ttcttgccaa
     6841 gagaagaagg aagccaacgc ggtgtggtat ttggcgaatt tcaattagga aatatgattg
     6901 tcggtacgat cgaagaaacg ggcagtttgg tgacagagta tcaaaaagga gagttagtct
     6961 gcacttatgg acccattcgt gaaacgctga ttacaaacgg tgttgataat tataaactac
     7021 gtaaacttga tcggttggat caatggaaaa atgcagtatg ttacgatcct gctcaattcg
     7081 ctttaggtgg tatccgggaa gcacatgttc gagcaggtga tgctgtagca atcttcggtt
     7141 taggcgctat cgggcaaatt gcgattcaat tagctaaaaa agcaggtgct actaccatcg
     7201 ttgggatcga tcccatagcg cagcgtagag aattagcaga aaaatacggt gccgattaca
     7261 cgctagatcc tatgaaagca gatgtcggtt ttcgtctaaa ggaattgaca gataaacgtg
     7321 gagtagattc agttattgaa acgagtggca gtgctgccgc attacaagct tctttaagag
     7381 ggatcggcta tggcgggatc atttcttatg ttgcctttgc taaacctttt ccagctgggt
     7441 ttaatcttgg tcgcgaagca catttcaata atgcaaaaat cgtctttgct cgagcatcta
     7501 gtgaaccaaa cccagattac ccaagatgga accgtaaacg aatcgaggac acatgttggg
     7561 aattattgat gaacggttac ttggattgtg aagaaatcat tgatccagtt gtgccatttg
     7621 cagaaagcgc agaagcttac atgcgttatg tagaccagca cccagaagaa agtatcaaaa
     7681 tgggcgttca agtccgagga ggagaacaat gaaattcggt acgcaagatc aagcattttt
     7741 cccaagagac attttagaaa aatttagatt tatcaaagac tgtggatttg aagaatacga
     7801 aatcgacggt aagttgttaa tagaaaatat cgacacagtc aaacaggcaa tcaaagaaac
     7861 agggatccca gtagtgacag cttgtaacgg ctacgatggg tggatcggtg actttatcga
     7921 agaacggcgt cttaatggtg tacgtcaaat tgctgagatt ttgcgtgcac taagcgaggt
     7981 tggaggcaaa ggaatcgtta tcccagcagc ttggggaatg ttcacttatc gattaccgcc
     8041 gatggtttca ccccgaagca aagaaggaga ctataaagca gtcagcgaat cacttcgtta
     8101 tttagataaa gtagccgaag aaacaggtac ggttatttat ttggagcctt tgaaccgata
     8161 ccaagaccat atgatcaatt tgttagcgga tgcgcgtcat tacattgact ctaatcaatt
     8221 gaaacatgtg cagatcatcg ctgattttta tcatatgaat attgaagaag atgatatttc
     8281 aaaagcattg actacgcaaa aagagtatgt gggtcatatc catttagcag ataatcatcg
     8341 ctaccaacca ggatctggcg caattgattt tactcgccat tttcaaacgc tacttcaaaa
     8401 tgagtatgaa ggttatatgg tatatgaatg tcgtttgcga ggagaaaatg aagtgaaaat
     8461 ttatcaggaa tcattgcaat acttgaaaaa ctgtctggaa acagcgcgtc atttaaatga
     8521 tttagagaaa gaatagagaa agaataacaa taagtaaata agcaaaggag ggagaaataa
     8581 atgaagaaag tagcaatcat aggcgctgga caagtagcag aaaaagtaca tgctgcttat
     8641 tatcaaaaaa gatcagatgt cttagaattg gccgctgtgg ttgatccagt cagccagcga
     8701 gcagaagact tttgccgacg tacaggattt tctcatgcgt atacatcagt tacacaaatg
     8761 ctgaatgaga tttctcccga tatcgtgagt gtctgtacac ccaatcgctt tcacttcgaa
     8821 catgtattgg ctgccctcga agctaatgct tcagtgatgt gcgagaaacc accagctatg
     8881 acagctgatc aagcaagaaa gatggcagag acagccgata aaaacgggca gattttggct
     8941 tatggattcc agcatcgttt ttctgacgaa gcaacaatga tcaagaatca tcttgatgtt
     9001 ctcggggata tttattacgt agaagcgaat gcgcttcgtc ggtctggtgt tccaggctgg
     9061 ggaacgttta tcgacaaaga acttcaagga ggcgggcctt tgatcgatta tggcattcac
     9121 atgcttgata cagcgatgta tattactgga tttcctaaag taaaaagcgt tcgggcgtac
     9181 agcttccaaa aaattggtac gaaaaaaaat tcagggaaat tcgggaaatg ggatccaagc
     9241 aaattcacag tagaagatgc aatttttggc acactggaat tagaaaacgg caagatcatc
     9301 caactgaata cttcgtttgc tttgaatatc agagaagaca aactgaatgt ggctttttgt
     9361 ggcgatcagg caggtgctaa tctgtatcca ggcgaactat tcgaagatgt agatggaaag
     9421 ctggtttcct tacaaaagac cacgccagtt aatgacccac atgaactaag tatggctcat
     9481 tttgtgaatc gggcgctcgg tgaccagact cagatgattg cagatggctg gcaaggatat
     9541 gtcatccaga atctggtgga aaatttatat cgttcggcag aaacaggaga agttattacc
     9601 ttatgaaagt agaagaaaaa cagtttgatt tagagtatat caataagtat gcgagtcaga
     9661 tgaccattgg aaatggattt tttggtatca gaggaagcca ggaggaagac tatcggaatc
     9721 aagtaagggg aatgtttgca gctggtgtat ataaccgacc tttaggagca gaatcagccg
     9781 agttagtgaa tctcccagat gtcatcagat gggaaataaa aatcgacggt gaacattttt
     9841 ctcttgagac gatgaaagtt cttgcatacg agcgggcact agatttagaa atgggagagc
     9901 ttaaacgcta tgcgctcatt gaaactgctc aaggaaaaaa agtggaagtc attacttgtc
     9961 gtgttgctga tcaaaataat ctccatcagg cagccctgaa agtggtcatc aagccgttga
    10021 ccgaagactg ccaagtagat gtgaaaacgg gtatcgatgg acagcaaacc aattttggta
    10081 cacagcagtt ggttgaaaaa gaactgcgag tatttggtga cgatttgatc agtgcatcct
    10141 accagacaac agaaagtaaa attgatattg ggattgcagc taaattcaat aaagcaggtg
    10201 tattccaagc aaaaaatcgc cggatcaccg cttccttttc agaaaagatc agaaaaaata
    10261 cgtcctttac gctggagaag atcatcgtgc tctctacctc tcttcagcaa acagacccgt
    10321 ttaagaaaag tattgcccaa gcccagaaaa gcgttagtta tacagaaatt ttagagcagt
    10381 cgatgtctta ttggacagat ttttggcatc agcatcggat aacgatccaa ggcgattctt
    10441 ctttcgatca gttagcgatg gacttcgctg cttaccattt acagattatg actccccgca
    10501 atgatccaag tgttagtgta ggggcgaagg gactaactgg cgaaggttat aaagggcatg
    10561 ttttctggga tacggaaatt tttatcctgc ctttcttttt atatcagttt cctgaagtag
    10621 caaagaattt gctgctgtac cgttatgatc gattagaagg cgcacggcaa aaagcaagag
    10681 attatcacta tcaaggtgca cttttcccat gggaaagcgc acacactggt caggaagaga
    10741 cacccaaatt tgctgcattg aatatcaaaa ccggaacaag acaagaagtt gcttcagctg
    10801 ccgcagaaca tcatatcagt gcagaccttg cttatgccgt tcaagagtat gtccaagcaa
    10861 cagaggatca atcgttttta gaaacaaagg gaaaaacgct cattcatgaa acagcagctt
    10921 tttggctgag cagagctgta aaagtcgatg atcatttaga gatacacaga gtcattggtc
    10981 cagatgaata cacagaatat atcgacaata atgcatatac gaactatctg gcgcattata
    11041 atgtggcctt agctgttaaa tatcaagctg gcgatccgct ttttttgaaa gaatgtcaaa
    11101 attttttaga taagttatat ttgccagtgc ctaacaaaga acagctgatt ccgcaagatg
    11161 acacgtatct cagtaagcca gttattgatt tgaccactta caaagaacgt cctggcagcc
    11221 agtctatttt acttgattat gcccgtagcg aagtaaatga actccaagtc agcaagcaag
    11281 cagatcttgt catgctgtta tacttattac ctgagtattt ttctcaacca atcgtttcta
    11341 agaatttgca ttactatgaa aacaaaacaa tccacgactc atcgttgagt aaagcgattc
    11401 acgccataga ggcttgccgt atccaagaaa tggaatgggc gtatcattta ttccaagaag
    11461 cgtgcctgat tgatttagga ccagatccgc attcatcaga tgacggaatt catgctgctt
    11521 cattaggagc actatggcta gcagttatat ttggtttttc aggtattaca gtaacgaatg
    11581 gaactctttc tatttctcca agacttcctt cagcatggga aaaaatttct tttcctttta
    11641 tttggaaaaa tcacaggttg ctatttgttt tgacaaaaaa acaaatagta ataaaaaaag
    11701 agacgaaaga aacattacct atttttgtca atggagacca ataccagctg gaaaaagaac
    11761 tgatcttgga acggagggga aaataatgcg tattctgatt gcgccagatt ctttcaaaga
    11821 aagtctgaca gccttagagg cagcacaagc cattcaatca ggttttcaag aagtttttgt
    11881 tcaggctgaa tatgatctgc tacctatagg cgatggagga gaaggaacgg tttcatcatt
    11941 agcagacagt ttaaggttga agcggcaaac agcagtcgtt actaatgcat ttggcaaaaa
    12001 caaagaaatc cagtacgctt cagacggtca aactgcgatt tttgaaatgg cagaaatcgt
    12061 cggattgaaa gatgtcccac taaaccaaca acagccactt aggttatcca cgcgaggagt
    12121 aggagaactg atacgacaat tgttgcaaca aggtgttcga cacatcatca tcggcgttgg
    12181 cggaagtagt accaacgatg gcggcatcgg catggcagaa ggtctaggtt atgcttttta
    12241 cgatcaagat aatcaaaaag tagaagcact gggagaaaat ctaggtaaaa ttgctacagt
    12301 tgataaaacg aacgtgccta ttgagctgat taaagccaaa atcactgtca ttactgatgt
    12361 tactaatctt ttatgcggaa aagaaggcgc ttcttttgtt ttcggaccac aaaaaggctt
    12421 gaaagaaaat gaattagcag tggctgacca agccatgcat gatttttata tgagatttgc
    12481 ccctcaagta atcgaggcat cgggcagtag tgctggtggt ggaatgggtg caggactgtt
    12541 agcatttgct tcagggaaaa tagtctctgg catcgactac gtattggatt tactggagtt
    12601 cgataaacgg gtacagcaag cagacctcgt aatcgtaggc gaaggacgtc tagatggaca
    12661 aagtctaaaa ggaaaagcgc cagttgggat tgctagaaga gtaccagagg gcgttcctgt
    12721 gatagctatt tgcggaagtg ttggtaaagg aagcgaaaaa gcagcagatg ttggcatttc
    12781 ggccgttttt ccgatccttc ctgcagctgt gcctttacaa gaagctttac agcaagccac
    12841 tgataatctt catcgcacag ctaaaaacat cgcatcttta cttcaagtcg ttcattttca
    12901 aggaggtaat cgatgaaaat caaagcagca ctattcgatt tagatggcgt tcttgtagac
    12961 acagctcgtt atcattacga agcgtggctg gttttagcta accagctgtc cattccattc
    13021 actgagaaag aaaacgagca actgaaagga atatccagaa ccgagtcact agagcgattg
    13081 ctgtcatttg gaaaaatgga acagaaattc tcagaaaaag agaaatcagc ctttgctgag
    13141 caaaaaaaca atctatatct tcaagcgatt caaaaaatgg atgaaacatc cgttttgcct
    13201 ggtgcaatag ctgttcttga gtacttgaaa aaaacaaaca tcaagatcgg attgggatca
    13261 gcaagcaaaa atgcacgcct cattttagaa aaaacgaatt tgacaagtta ttttgatgtc
    13321 cttattgacg gcacgcaagt atcaaaagca aaacctgatc cagaagtttt tctcaaagga
    13381 gcacagcaat tgaatgtacc gccaaatgca tgcttggtca ttgaagattc agaagctggt
    13441 tgtcaagcag ctttggctgg taacatgcat gtattgggaa taggtgaaaa cataaatctt
    13501 ccttctgctg aatatgtgat tcctgattta accgtttttg atcaagtacg ttcgttttgg
    13561 catttatcag aagccgtatc acgtatataa tagtttccgt tttttctgtc acaagcaaaa
    13621 cgttatcctc cttttggaaa tcaaggtatg atgagaaaaa agggggattt tatatgacaa
    13681 aaaaagcagt tttcgcaggc ggatgctttt ggtgtatggt caaaccattt gaagagcagc
    13741 cagggatcat ttctgtgaca tccggttata ctggcgggca tgtaccaaat ccaacttatg
    13801 aacaagtaac aacaggcaca acagggcata cagaagcagt agagatcgaa tatgatccag
    13861 aagttatttc ttatgatcag ttggtggaaa tctattggca gcaaaccgat ccgactgacg
    13921 cattaggaca gttcgctgat cgcggtgatt cttatcgtcc agtgatctac tataatgatg
    13981 aagaagaacg aaatattgca gagcgttcaa aacaagcatt gcaagacagc gggcgattcg
    14041 ataagccaat cgtgacaaaa atcgaaccaa gaagcgaatt ttatcctgca gaagattacc
    14101 atcaggatta ttacaagaaa aacaagctcc attacaatct ttatcgagaa ggttctggac
    14161 gtgcaggttt ccttcgtcga cattggggcg tcaagaaata agaagccgaa aaagctactt
    14221 atggaacacc gtatatcaga ggttgtaaaa ccagcatttt gagctaatac tgagggtcag
    14281 ctgattgaac accatttagt ggagaggttg tgaacctgtc gcctagctcc aagtcacaag
    14341 gatttggtaa gagaacacta tatatcagag gttgtgacaa gtcgtttgtc acaacctttt
    14401 ttcaatacct aagatgaagg acaatcagca acgcactgct caaaaaagga atgaaaggca
    14461 gcttttccaa ctttttttta tgacagataa agtaaacaga aaaaacggat attccaaaca
    14521 gactagcaag aaacaagatc tgaagcaact cttctagaga caagccacca ctccaagaaa
    14581 gcatcaacag agtatcgcca gctccgagat aggattgacc atagcgaagg cacacaccgc
    14641 ctacgataaa cgttaacagc acactttgcc attggaagac gccggcctgc aaccaaaaaa
    14701 tccataaaat tgcccaagaa cagaatagcg tgtgagaatg gaccatgaag taaaataaat
    14761 ccatcaacga aaatagcaaa gccgaaagca tccatatgaa cgtcgaaaaa tttcttgcgg
    14821 aagaaaaagt aaagaaccag gcaaaaagac caccacataa ggcttctgcc aacaaatagt
    14881 agaagggcaa ccgacacctg caatagcggc agcgaaatcg ttggacgatg atcgagagaa
    14941 tcggaatcaa ttcataccaa gaaagcgaac gacagcattt gacacaatga gatctaggat
    15001 aaataataga gtgacctaac ggaatccgct gggcggttaa acataaaaat gatccgatac
    15061 agcaaccaat gataaaataa agtaacacgc catctccccc ttttcaaaac caagatacgc
    15121 aagcttaaac taaatttttg tacatacata aaatttgagg tgaaaaaatg aacgtttcaa
    15181 tcggattaga tatcggaacc acacaaacca aagcagttgc tttcacagat gaagcccaag
    15241 aagcagcatc cgcttatttt cgctaccctt tgatccaaga aacacaaggg atggcagaac
    15301 aagatcagga attgatcttt caaggtgtct gcaccgttat aaaagaagta attaaacagt
    15361 tgccttcaga cacaatcatt caatttgtct ccttctcctc tgcgatgcat ggcctgatat
    15421 tgttggatga agagaaaaca ccgttatctc gaatgatcac ttgggcagat aaccgagcag
    15481 cggacgaagc agaaaaactg aaatataccg tgcttggcaa agaattttat cggcagactg
    15541 ggacgccgat tcatccaatg acaccattga acaaaatcaa gtggctgcaa aacagccaac
    15601 ctgaattatt caaaaaaact gcttattttg tcggtatcaa agactatatc ttttatagat
    15661 tgtttggcga actgatcagc gactacggaa cagcttcagg aactggatat tttgatatcc
    15721 atgaattcca atgggcagaa gaagtgcttg actacttgaa cattcgaata gagcaattgc
    15781 cgcaagtctt tccttccacc tatcaagtaa caggtctacc atcaaaaaca gcagcagaac
    15841 taggtttgcc aaatgatata tcatttgttt tgggaggggc agacgggccg ctttctaatc
    15901 tagggttagg tgcttttggt gatacgatcg ccgctttgac cgtaggaacg agcggagcac
    15961 ttcgttttat tactactcag cctcagttcc atccagaaat ggagacgttt tgttatgttc
    16021 tggatcagaa acattgggta gtgggaggag cgactagcaa tggtgctggc atctttgatt
    16081 gggcagggca tacattttta caggaagtcg ttcaatctgc taaagaaaaa ggagaaaatc
    16141 catatgatgc actgctttcg gctatcgctt ttgtgccagc gggtgccaat ggtctgattt
    16201 ttcatcccta tttacttggt gagcgagcac cgctttggga cgcagatgcg tttggcagtt
    16261 ttatcggttt acagcggcaa catacagaaa aagaaatgat gaaggcgatt ctagaaggga
    16321 tctgtctcaa cctttatcgg attttaaaag gagtttgcca ggaaaatcag ctcacagaga
    16381 tccgtgctac aggcgggttt gctcaatctc cgatttttcg tcagatgatg gctgatgtac
    16441 tgggttaccc gcttgttttc cctactgtca cagaagcatc cgcattagga gctgtgattt
    16501 taggctggag aagcatcgga aagatccaaa gtatcagtga agcacaggaa ttgatagaat
    16561 tgaaagagca agttggagta caagaaactg atcataaaaa atatcagaaa atctatccat
    16621 tatttgtttc gacacaaaag catttagcac agacttatca gcaatttgct caactgcgag
    16681 aagaattagc tgattctgaa aaatgattgg ctttacggat aaaaaagcga actgaaaatc
    16741 gttctcaggt aaatgatttt gttgtacttt tcattgaaag tctactatta ttttaagtgt
    16801 aagaaaatgt taggaggcaa gaaagatgaa attccaacaa accaaagaag tattaaatca
    16861 attagttgca gatctaagcc aaatgtctgt tgttgttcac caaacacatt ggtacatgag
    16921 aggaccaggt ttccttacat tgcacccaat gatggatgag ttcatggatg atttgaacgc
    16981 tcagttagat gaagtatccg aacgcttgat cacattagac ggttcacctt attctacatt
    17041 gcgtgaattt gcagataaca caaaaatccc tgatgaaatt ggccgctggg atcgtactat
    17101 tccagaacgt ttggaaacac ttgttgcagg ctatcgttat ctagcagatc tttaccaaaa
    17161 aggaatcgaa gtttctggag aagaaggcga cgatccaaca caagatatct ttatcgaatt
    17221 caaaacagcc acagaaaaac gtatctggat gatccaagct catttgggca aagcgccaga
    17281 gatcgacgcg taaaaactgt tgttgaactt gaccgaaaaa gaggttgtga aatcagcgtt
    17341 ttgacctgag tattagagaa acaaacgtca aaatagttcc tcatattttg ccgttttttg
    17401 agctaatacc gagggtcagc tgattgaaca ccgtttacca agaggttgta agcctgccgt
    17461 tcagctccga gtcacaagaa acaattttaa aaaacagctt cttatgtttt atggatattg
    17521 tgacttgtga ccgaggagtt ggcaggagaa caccgtttat tcaaaataag gggttgtgac
    17581 aagacttttg tcacagcctc tttttgtttt tcattttgac aggaaacgac ccttttatat
    17641 aaaagaaaga aaagaagtaa agtttcatat aaatttttca atcaagcaga aaaacgttga
    17701 cattgactag attagcgggt aatatgttaa atggtattgt ttgccccaca aagagccccg
    17761 gaaactcgaa gtgtatgtca aacatcagaa cttaaattgg aggaaaataa cgtgcgtaca
    17821 acatatatgg ccaaaccagg cgaagtagaa cgtaaatggt atgtagtaga cgcaactgat
    17881 gttccattgg gacgtctttc aacagttgtt gcatctgtac tacgtggtaa aaataaacca
    17941 actttcacac ctcatttgga tactggcgat ttcgtcatcg tcatcaatgc agacaaagtg
    18001 aaattaacag gtaaaaaagc gactgacaaa atttattacc gtcacagcaa ctacccagga
    18061 ggattgaaat caatcactgc tggcgaattg cgtgctaaaa attctcgtcg tttgatcgaa
    18121 acttctgtaa aaggtatgct tcctaaaaac actttaggcc gcaaacaatt tacaaaattg
    18181 aacgtatacg gtggagcaga acatccacat gcagcacaac aaccagaagt tttagacatc
    18241 acaaacttaa tctaatagga gggaatttca ttggcacaag ttcaatatat cggcacaggc
    18301 cgtcgtaaaa acgcagttgc tcgcgtacgt ctagtaccag gaactggcaa aattactgta
    18361 aataaaaaag atgttgaaga atacattcca catgctgact tgcgtgaagt aatcaatcaa
    18421 cctttcgctg ttactgaaac aaaaggcgca tatgacgtat ttgttaacgt aaacggcgga
    18481 ggatacgctg gacaatcagg agctatccgt catggtatcg ctcgtgcatt gctagaagtt
    18541 gatcctgact tccgtttagc tcttaaacgt gctggcttac ttactcgtga cgcacgtatg
    18601 gtcgaacgta aaaaaccagg tcttaagaaa gcacgtaaag cttcacaatt ctcaaaacgt
    18661 taatatcctt tatatatcaa cgtttctggc acttttcaat tatttggaaa gtgcttcttt
    18721 tgtttttaag aacacattta agaacacata tcaatcacac ttattcaatc ctctctgaaa
    18781 agcttcaaaa acagccttat caactatatc tggtgtgttc acatatatct ttgttgtaga
    18841 aatatctgag tgtgttaaag catttgaaat ttgattcata tctgctccac cttgtctagc
    18901 tatagttgca taagtatgac ggagtttgtg tggagataaa tgaactaagt caggatgcct
    18961 tcttttaatt gaattgattc gatagtttag gtaatcggca tgaacaggac aatttacttc
    19021 tccagatggt ttagtataag taaagagata ctgatctaac gtttgcttaa tttttaattt
    19081 caacaattga tcagcttgta ccgatttcca ttcacttagc aatgtcatta caacttctgg
    19141 tacttgaatg acggtatctt ttcgaccttt tgtaaacttt tttctttgat atttatctaa
    19201 agtatgttta agacggaccg tttgtttttc aaaatcaata tatttccatt gcaaagcgta
    19261 agtctcactt tttctatcac caagatacag ggtaatcata aaaagtgtgt aatcatgaaa
    19321 agtaagtaaa tgattattaa aatcatcatt tactgcttct atccaattag taagttcttt
    19381 tgatgatagt gcttgcttac cttcttgtat tcttttttct tctaaagcat tttttttagg
    19441 tgcagtgata ctttgaataa ttttagtagt tcgattaaat tcgatataat ttagtatttc
    19501 tgcaatatcg aacatggaac gaacatatcc ttttatgatt tttatatttg catattcttt
    19561 cgattttttg gttaattcat ctgatattat ctcagtattg atatttagat aattcattgc
    19621 gtattcacca aacataggta aaatatgcaa ccgaaatata tcttttgtat tactaatggt
    19681 tatatcacta ggaggcctgt ttgatctaat tgtttgacct aattcatatc taggaagcca
    19741 tttagattcg taaaattttt taaacgttat ttttcctttt aattctaatg agtttgcatt
    19801 ctcctctctc aaaacttttt ctattttctt cttcatatca ttttcggctt taatcgccaa
    19861 ttgcctattt ggaaatgttt tttgatactt ttctgatgca attcctgtta tttctttaaa
    19921 cctttttgga tatctcagat tagttttata tttcccattt gaaagctttg taggcaaaat
    19981 cctcactcct taaaaaaagt aaggcagtat atttcactaa ttttagtata tgcggcgaga
    20041 agaaaatttc aagttatttt aaatgtattc ataaagtctt taatatcttc tacgtcaaag
    20101 cgaactacac caccaactct tattactggg aaattatata tacgaatcca cttatctaga
    20161 gtattattat cgattcctag aaatgcacag gtttgttttt tattcaggta gactctggat
    20221 tctataaaat catctcctaa aatagtagtt atgaaatttt tgaattgctt tgggtaagca
    20281 cataggaatt tcacctctcc ccagtttacg gcgagcctta cggaagtatc attatttgct
    20341 gctattgtca tggcattttg ttttcccaga acaaaaagaa atctctaagt atttgtcgct
    20401 aatcaggtca tggcgtactt gagtttctag ctcgaatagc agggatcgtt attcaaaaat
    20461 tgtatttaat tgtcaatgat caaaaatagt ttttttccta ttcactatta ataacgataa
    20521 acatgtataa aaagacacac tacgaaaaaa gttaaatgga gtttactgat tttcatattt
    20581 gtatatggaa cagacatagt cttgaataat ttttataaat gttttgatgc ttatcaactt
    20641 attcaacccg ctatccactt caagtataat ttttccatac gccaataaag tagttttagg
    20701 agcatgttct catttgagaa cgctcctttt ttatatattt tgaaagctac ttactatacg
    20761 cgtagtttca aatagttttg tcattctaat cttcagcaac agaaaaaaat ctaaactata
    20821 aaatttaggg ttgactaaaa tataattttt gtataccata tgatcgtgat aatcattatc
    20881 atttagaagg agaaagttat gttagaagtg aaaaagctta atgtttgtta taacgatttt
    20941 ttagcattga acgagatttc tttaaaaata caagaaggtg ctttaacagg tattattggt
    21001 ccaaatggtg ctggaaaatc cacattgctt aaagcaatgt taaatattat ccctcatcag
    21061 ggagaggtct ccattaataa tgaagatatc aataaaaaac tggtgaagat tgcatatgta
    21121 gagcaaaaag ctgatattga ttttactttt ccaataaaag taaaagaatg tgtatctatg
    21181 ggaacatatg ccggaatgaa agtttttcaa aga
//
LOCUS       DAXLPY010000049        20663 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.049, whole genome shotgun sequence.
ACCESSION   DAXLPY010000049 DAXLPY010000000
VERSION     DAXLPY010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.049"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..261
                     /locus_tag="ACF3UF_001879"
     CDS             <1..261
                     /locus_tag="ACF3UF_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671980.1"
                     /translation="DLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDFI
                     LGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            440..997
                     /locus_tag="ACF3UF_001880"
     CDS             440..997
                     /locus_tag="ACF3UF_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671981.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1696..2217)
                     /locus_tag="ACF3UF_001881"
     CDS             complement(1696..2217)
                     /locus_tag="ACF3UF_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFD3671982.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            2416..6108
                     /gene="nifJ"
                     /locus_tag="ACF3UF_001882"
     CDS             2416..6108
                     /gene="nifJ"
                     /locus_tag="ACF3UF_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFD3671983.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLHHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLNLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            6297..7184
                     /gene="cdaA"
                     /locus_tag="ACF3UF_001883"
     CDS             6297..7184
                     /gene="cdaA"
                     /locus_tag="ACF3UF_001883"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFD3671984.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            7181..8350
                     /locus_tag="ACF3UF_001884"
     CDS             7181..8350
                     /locus_tag="ACF3UF_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFD3671985.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            8374..9729
                     /gene="glmM"
                     /locus_tag="ACF3UF_001885"
     CDS             8374..9729
                     /gene="glmM"
                     /locus_tag="ACF3UF_001885"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFD3671986.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(9801..11606)
                     /gene="glmS"
                     /locus_tag="ACF3UF_001886"
     CDS             complement(9801..11606)
                     /gene="glmS"
                     /locus_tag="ACF3UF_001886"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFD3671987.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            12015..12305
                     /locus_tag="ACF3UF_001887"
     CDS             12015..12305
                     /locus_tag="ACF3UF_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671988.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12318..13343
                     /gene="sppA"
                     /locus_tag="ACF3UF_001888"
     CDS             12318..13343
                     /gene="sppA"
                     /locus_tag="ACF3UF_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFD3671989.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            13346..14005
                     /locus_tag="ACF3UF_001889"
     CDS             13346..14005
                     /locus_tag="ACF3UF_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFD3671990.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            14162..15094
                     /locus_tag="ACF3UF_001890"
     CDS             14162..15094
                     /locus_tag="ACF3UF_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671991.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            15248..16537
                     /gene="tig"
                     /locus_tag="ACF3UF_001891"
     CDS             15248..16537
                     /gene="tig"
                     /locus_tag="ACF3UF_001891"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFD3671992.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            16784..18034
                     /gene="clpX"
                     /locus_tag="ACF3UF_001892"
     CDS             16784..18034
                     /gene="clpX"
                     /locus_tag="ACF3UF_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFD3671993.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            18117..18704
                     /gene="yihA"
                     /locus_tag="ACF3UF_001893"
     CDS             18117..18704
                     /gene="yihA"
                     /locus_tag="ACF3UF_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFD3671994.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18778..18933)
                     /locus_tag="ACF3UF_001894"
     CDS             complement(18778..18933)
                     /locus_tag="ACF3UF_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFD3671995.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            19069..20397
                     /locus_tag="ACF3UF_001895"
     CDS             19069..20397
                     /locus_tag="ACF3UF_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671996.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            20408..20617
                     /locus_tag="ACF3UF_001896"
     CDS             20408..20617
                     /locus_tag="ACF3UF_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671997.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
BASE COUNT         6831 a         3603 c         4441 g         5788 t
ORIGIN      
        1 gatctaggaa tctattttag tcgaggaagt gcgcaatatt atatggggga aaatgtacaa
       61 tcaatgtcat taaaaccaca tatagccctt agaaatctcg aggaaggttt taaaagagag
      121 gtagacttta tattaggaga aagtggatac ataagaactg tacttaattt cggagaagcg
      181 caagaagttt tgacacaata cggaattacc ttaatcaact gggaaatatc tgaaccgatt
      241 gttaacaatt ttggtgatta gaaaacaatt acgataaata gaaacaagcc aaatcatcag
      301 caagtaaaag ctgatgattt ggcctttctt atacgagtag taggaattca tagcgaatat
      361 tattacgacc agtagatatt ttgatattaa aggagtatta cgaactaata tgtgagaatg
      421 tagaggtgat gtgcgaataa tgagaaattt atcaaataga aacaaaatat taatcattat
      481 tgttgttata gctgtgtttc atctgggaac gaatgcggtt ttaagtagaa taatattggg
      541 tcctaagcca ccaagaccag aaattacccg aggggagttt gattttagat tagaatatga
      601 agtagatggg gaaaggattg tgatagaaga tacaattgtt gcattatttg atggattttc
      661 tgcagatgca ggtagcatgg catggtatcg cacgtggcgt ctacatttag caagtgatag
      721 acgatcacga aatatcttat tagatgaatt agaggatggt cgaagaatat attatgtccc
      781 agaaagtgct aactattcta tgggagatgt acagaaaaaa agagagccta atcctaattg
      841 gtatccattt aatggcgtaa caatagaata tccacgcaat aaaacacctg aaataggtgc
      901 aaaatttata agtggtttag aagatctgta cgataggttt ggaatccgtc ttattagttg
      961 ggaacacgat ccaccaatag aaaatcgctt tgaataatcg aaatctacta atccatttca
     1021 tcagccagtg aatgttgtaa tggaacaatt tggtttagtg ttcaaaacca ttgaaatact
     1081 aggctgtgat cagcaaaaat gaatctgaat aaaaaagaga gcaactatta gctgagagga
     1141 gttaatagtt gttagcttta tacgaatcaa agtggcaaat acagatgcgt atgcatttgt
     1201 gtttgccatc ttgcgtttgg tagacgagat aggtataagc taaagaaaca acttgtttaa
     1261 aataaacgac ctagctcaac aaatgaccat ctaatcaact aacagcatac ataaaagcaa
     1321 ctatttttga agtagaattg aaatcgggat aacttaaaaa gtgattggga tactagtgag
     1381 aatcaccgta cataaatatt actcgttaag ggaaattgag aaattttgta tgaaaattta
     1441 agaattagtt agtatgcgca agtcaaaaat atgaataaat tatttggtgg agataatttg
     1501 cttagcttgt cataagaaat gagataatct ggcagatgca agcttttgga caccatttat
     1561 tcggaataag gaggctggga cagaagcgtt taactccaag aaataagaag gagttgcttc
     1621 tgcttccgcc gtttatacgt gtttagagcg tgagacaaaa gtgttcttta cttttgtccc
     1681 acgctcctta tttttttatt ttgtttggat caattctttt aattcctcta ttgaaataga
     1741 ttcatcaaag atttctttac ccaagatgac agttggaaca aatcgaatat gtgcttgctc
     1801 agcttcgttg atgacagctt ggctcagctg ttcgtctttt tgttctgtca gctttagttt
     1861 atctactgca aaatccgcta cttcttggag agaaagatgt ttccactcgt cttgagtatc
     1921 gaatatttgt ttgatctctt tgatcgcttt ttggccatcg ctgattgtga gataccggtg
     1981 catcacgttc cctcgctgta agctttcttt ttctttatcg aacaatttga tcactcgctg
     2041 caattgcccg ctttggactg cttcttctaa tagctcataa gattcttcaa accattgtcg
     2101 gcaatacgga caagctaagt tgatgaattc gaccattttt ttaggagcat tcgatgaacc
     2161 ataaaggatt cctttttgtg tatttgtttt cgttgcatca atcactgata tatccatgtt
     2221 aaaacacctc tttcgcttat agtttataca tgtctgacaa aaaaaggcaa cgatttagac
     2281 tgtttgtcta aaaattagat gaccaattca aatagataca tgtaaaatat ttttataaat
     2341 aaaagaaaaa aatggcatgt tttacgttat aatggaacag ataataagag agaatatgaa
     2401 caaggatgat gaatcatgcg aaaaatgaaa acaatggatg gcaatacggc agccgcatat
     2461 atttcttatg catttaccga gattgctgca atatatccaa taacacccag ttcgaccatg
     2521 gctgaattag tagatcaatg gtcagcagca ggaaaagaaa acgtattcgg tcaaccagta
     2581 aaagtagtag aaatgcaatc cgaagcagga gcagctggtg tggtccatgg atcattgaaa
     2641 actggtgcac tgacaactac atataccgct tcacaagggc tgcttttgat gataccgaat
     2701 atgtacaaga ttgctgggga actactgcca agtgttttcc acgttgctag tcgggcagtg
     2761 acgacaaatg cgttgaatat tttcggagat cacggagacg tgatggctgc aagacaaaca
     2821 ggatttgcta tgttagctga aagcagtgta caagaagtga tggatttagc acctgttgcc
     2881 catcttgctt ctattgaagg agaagtccct tttttgaatt tctttgatgg attccgtacg
     2941 agtcacgaga ttcaaaaaat cgaagttttg gaatatgaag aattagctcc tctgatcaat
     3001 caggagaaat tagcttcatt tcgtaaacga gggatgaatc ccaatcatcc gactgttagt
     3061 ggtacgaacc agaatccaga catccatttt caacaacggg aaacgatcaa cccctattat
     3121 gataaattac ctgaaatcgt tcaaaaatat atgaaagaga tcaaccgatt acgaggaact
     3181 tcttatgact tggtgactta ttacggagca gacgatgcgg aagaagtcat tgtttctatg
     3241 ggatcagttg cacagacgat tgaacaaacg attgattact tgaatgcaaa cggacggaaa
     3301 acaggttttt tgaatatcca tctttatcgt ccttttccag tggaaacatt cgtgcaaaag
     3361 ttgcatcata cagtaaaaac aattgctgtt cttgatcgaa gtaaagaacc aggggcaggt
     3421 ggagaacctc tcttattaga cgttcaaagt gcgttatatg attctgaact tcgcccggct
     3481 gttattggtg gtcgctacgg attggggtct aaagatgtga ctcccgacca aatctcagca
     3541 gtttttgatg aattgaaaaa agacccaagc atacgcaaaa aacggtttac catagggatc
     3601 gtggatgatg tgacttatca atctttggaa ccaaaggaaa gtctgaattt gacagaaccg
     3661 caaacattcc aggccaagtt ttggggattt ggatctgacg gaacagttgg agcaaataaa
     3721 tcagctatca agattattgg agatcacacc gataaatatg cgcaaggcta tttttattat
     3781 gattcgaaaa aatctggcgg tctgactgtc tctcatcttc gttttggaga tacgccgata
     3841 cgttcagcgt atcttgtcga gcatgcggac cttgttgcct gtcacacacc agcttacctg
     3901 catagctatg acttggtcaa aggattgaag ccaggtggca tttttttatt gaatactctt
     3961 tggagcgacg aacaattaga aacgcatctg cccttaaaat taaaacgtta cttggctgaa
     4021 aataacatta gattctatac gatcaatgcc atgagattgg cccaagaagt cggtttggga
     4081 cgccggatca atacggcaat ggaaacggct ttttttaaat tagctgacat cattcctttt
     4141 gatgaggtgc ttccgctgct aaaagaagaa gccctgaaaa gctatggaca taaatcaatg
     4201 gctatcgtag aaaaaaacat acaagcaatc gatcggacga ccgaactgct tcatcaagtc
     4261 gcgatcccag accattggag aacgttggag atgcctgaaa aaatcaataa aaggaacact
     4321 ggttatatac aagaaatact tgaaccagtg aatgcacagg aaggaaatca actctctgtt
     4381 ggtacacttg tagcaaatgg aatgacaact ggcgaaatgc ctttaggaac ggcttctatg
     4441 gaaaagcggg gcgtcgcttt agaagtacct gagtggatta gtgatcgctg tacgatgtgt
     4501 aatgaatgtg cctttgtttg tcctcatgct gccatccgtc catttttagc agatgaagag
     4561 gaaatggaag aagcgccaga aggatttatc gtgagagaaa tgcgaggcgc agacggcgta
     4621 aaataccgta tccaagtttc agtggaagac tgtacaggtt gtggtctgtg tgtagaggct
     4681 tgtcccgcaa aagaaaaagc tttagtgatg aagccttatg aagaacagaa agaacaagct
     4741 gtgaattggg cttttgcaat gacattaaga caaaaagcaa atccagtcaa aggaaagaat
     4801 actgtcttgt ctacacaatt caatcaaccg cttcttgaat tctcgggcgc ttgctcaggc
     4861 tgtggcgaaa caccttatgt aaaattattg acacaaatgt tcggtgatcg aatgatgatc
     4921 gcgaatgcga caggctgttc ttctatttgg ggcggtgctt ctcctgcttc tccttatacg
     4981 accaatgaat gtggtcaagg gcctgcatgg tcaaattctt tattggaaga taatgctgaa
     5041 tttggttatg gtatgcttct agcggcacag actcgtcgcg aggctttggc aagttcaatc
     5101 aaagaagtat tgccaaaagt atcagaagaa ctacgagaat tgatggaaga ctggttagta
     5161 cacatgtttg agagtgaagg aacgcagcaa agagcagcaa aactgcaagc tgcgatcgaa
     5221 agcgaacgat caattttccc tgaactggag gatatataca agagaaagga tctattcgta
     5281 aaaaacagcc aatggatgat tggtggagac ggatgggctt acgacattgg ttttggcggg
     5341 atcgatcatg tacttgccag cggagcagac gtgaatatcc ttgttttgga taacgaagtc
     5401 tattccaata ctggcggtca aacctcaaaa gcaacaccag cttcggcaat cgctaaattt
     5461 tcggctagtg gaaagtatgc ttcaaagaaa gatctaggaa tgatggcgat gacatatgga
     5521 aatgtttatg tggcgcaaat tgcttcaggt gccaatcaaa tgcaaacgat caaggcattt
     5581 gaagaagcag aaaagtatcc tggtccttct ctgattattg cctatacgcc ttgtatcaca
     5641 catggcttgc ttggcggaat gaaagaatcg cttaaagaag caaaagaagc tgtttcttct
     5701 ggttattggt cattatatcg atataaccct acaatggtcg aaaaaaacaa gaacccaatg
     5761 actttggact acaaaaaacc tgatttctct gctatgcctg atttcatgag gaaacaagtt
     5821 cgcttttcct cgctagataa cgcaaatcca aatcttgcaa aagctttatt tgaaaagact
     5881 gtccacgacg ctaaaacacg tttttacaac tatgctgcac tgacgggaga attagaaaaa
     5941 atcaagaaac gacttgaacc agaggaatct atcgatgtac ccgttaagac tagaaaagaa
     6001 aaaacgacgg accttgaagc agaagaaaga agagctgcta gaagagctgc cagagcagaa
     6061 cgacgtaaaa aaatggaaca agctacaaaa gaaaaaaagg aaaaataaca gaaaaaatat
     6121 aatgaataat tctctgaagt ttaaaaatat ttattgcaga gaaaaataaa acgcatactt
     6181 gcaattttct tgaaaattat gcgtttttct caagaaaaat acgagcatat cagcctctaa
     6241 aattaaaaca tatgatatac tagagaggaa atctcaaaag agaagagagg ctttttatgt
     6301 catttcaaat cggggaactt tttaatttgg actattggca gcaaatgttt tccggtgact
     6361 tgttctctct gaattttttg gtgaacatac ttgatattct ggttgtctgg tatcttgtat
     6421 acaaactgat ccaactgctg cgaggcacaa aagcgattca gcttctgaaa ggtgtagcta
     6481 tttttattgt tatccgaatc gtagcggaaa tcattggtct gcacaccttg tcttggctga
     6541 tgaaccaagt cattacgtac ggggtgatag ctgctatcgt gatttttcag ccggaaatcc
     6601 ggagaggact ggaacatctt ggacgcagtt cgcttttcaa acaatcaaaa agcgaacagc
     6661 aggaagatga gaagatgatc ttgtcttttg acaaagccat ccaatatatg tccaagcgaa
     6721 aaatcggtgc gttgatcact atcgaacgtc atactggatt agatgagtat attgagacag
     6781 ggattgcttt agatgcagat atcactgggg agctgctgat caatatcttt attcctaata
     6841 caccgctgca tgacggtgca gttattgtaa aagaaggaaa gatcgcagta gcaagcgcct
     6901 atcttcctct atcagaaagt atgttgatcc ctaaagaatt cgggactcga caccgggcag
     6961 ctgtcggtat aagcgaagtc agtgacgcga ttaccatcgt tgtctctgaa gaaaccgggg
     7021 acgtcagcat cacgttagat aatgaactga tggctggctt atcccagcaa gaatatttgg
     7081 caatcttgcg tagagaacta attgctgaag agaaaacaaa aaacaagaaa aacgtgattc
     7141 aatctttcct agacggtatg actaagggag gggatcgcaa atgatctcaa aagagaaacg
     7201 gacaagcatt ctttacagtt ttattgcatt gctgttcagt attgcgctgt acttcaatgc
     7261 aaatggccag tccgttccaa atacgctttc tggaaatgaa gcgtataatc aaacagttac
     7321 gggggtgccg atcaagattt cttatgattc aaagcgctac tatatccatg gatatgaaaa
     7381 tgcagtgact gtcaaacttt ccagtgcaaa ccgagttcag ttgaatgcag aggcaaacga
     7441 agatacacgg atgttccgcg tcacagcaga tatcactaag ctgggcgaag gaacacatga
     7501 agttccgcta aaaattcaaa atttgagcag tgctgtcaca gcaaagatcg aaccatcgac
     7561 tattacagta acggttgaga aaaaggtaat aaaagatttc gatgtggaaa cgttgattcc
     7621 ttcaacgttc acaccatctg gatatgaact tgatgatact tccgttagtc ctaaaaaagt
     7681 ctctatcact acaggtgaca aaacattggc agaaatcaaa cgagtagtag ctgatgtgga
     7741 cgcttcgatg gtcacagatg atgggattaa tagtgaggtc ccaatacagg cgctgaatgc
     7801 agcaggggaa gtattaagta tcgtctctga tccagtgcaa gtaacagtga gagctgattc
     7861 gatcaagcca agcaagtcgg tacgacttta tgggatacag caaggaacac cagctgccgg
     7921 ggtagaaagc tatgatttca gtttttcaaa actggaagca gaagtaagcg gctctagcga
     7981 tttgcttgca tcgatcggtg acagtattgc tgtaccgatc aatgtctcag gtatcaatca
     8041 tcgaacaact cgtaaaattg aaataccagt agaagagggg ttaagtatca agcccgaatc
     8101 agttagtgtg gagattacac ccgtgttgca aacgtcaagc agtagctctg cttcgacgag
     8161 cagtcggaca caagaaaata caagtacgag tagaagtatt tcatctgctg attcaggaac
     8221 ggaaccatcg acaacaacca tttcttccag ttcggaatct gggacaagca gctcgaccac
     8281 aagtacagaa gaaacatcag aaacaagcga atcaacacaa atgagcagaa caaattcctc
     8341 agaaaattaa gttaaaggag taattttaca actatgggta aatattttgg aacagacggc
     8401 gtacgcggtg aagccaacaa ggaacttacg ccagaacttg catttaagct gggacggtgc
     8461 ggaggttatg tcctaagcca gcatgaagaa gaaggaaaac gcccacgcgt gttagtaggg
     8521 cgggatacaa gaatctcagg tcaaatgtta gaagaagcgc tgatttcagg acttttatcg
     8581 gtgggtatcg aagtgttcca gctaggtgtg atctctacac caggtgttgc ttatctgaca
     8641 cgtttgcaaa aagcaagcgc aggggtcatg atttctgctt ctcataatcc agcacaagat
     8701 aatggaatca aatttttcgg tgcagatggt tttaaactag tagatgacca agagctagaa
     8761 attgaagcat tattagatgc tgaagtggat gaattgcctc gtccatcagc tgaaggattg
     8821 ggaactgtag aagaatttcc agaaggctta ttgaaatatt ctcaattcct tgtacaaacg
     8881 atcaacggtg acctttccgg tttgaccatt tgtgtcgatg cagcaaacgg agcaacttca
     8941 acaagtgtta atcgtttgtt tgccgatctt gaaacagatt tttatacaat gggcacaaat
     9001 ccagacgggt taaatatcaa tgacggcgta ggctctaccc atccagaacg tttagctgag
     9061 atggtcgttg aaaaaggagc agatgctgga ctagctttcg atggcgatgg cgatcgtatt
     9121 attgcggtgg atgaacttgg aaacattgtc gacggtgata aaatcatgtt tatctgtgct
     9181 aaatacttgg cagaaaaaaa tcgattgaaa aaagatacga tcgttacgac tgtcatgagt
     9241 aacttaggat tccacaaagc ggtggaagga atcggtttga aagatgtcgt tacacaagtt
     9301 ggtgatcgtt acgttgtaga agaaatgcgc aaaaacgatt ataactttgg cggcgagcag
     9361 tctgggcaca tgattttctt agattttaac acaactggag atgggatgct ttcaggaatt
     9421 cagttactga atatcatgaa acagacaggt aagaaattat cagagcttgc agcagaggta
     9481 acaatctatc cgcaaaaatt agtgaatatc cgcgtaagtg ataaaaacgg tgcgatggat
     9541 gttccggcaa tcaaaaaagt gattgaagag gcagaagctg aaatgggatc agaaggaaga
     9601 atcctagttc gtccttccgg tacagaacca ttacttcgag tgatggcaga agcgcctact
     9661 gatgagaaag ttaattacta tgtcgataaa atcgcggcag tagtcaaaga agaaatcgga
     9721 ctggattaag agatattttc ataaaaaata aaagaacaag gaccagtgtc agatgtctga
     9781 cactggtcct tgttctttta ttattctact gtcactgatt tcgctaaatt acgtggtttg
     9841 tcaacgtcga atccccgtaa tagcgttgcg taatatgcaa gtaattgagt cggtacgact
     9901 gtggttagag tagttagata agggtggaca gttggtagca ccagctggtc actttccttt
     9961 tctaatccct ctgagacaat aactagtgtt ttagcgccac ggctttcgac ttctttcagg
    10021 tttcctcgag tatgcgcacc agtcacttct tcactgatga ttccgatcac tggtgttcct
    10081 tcttcgatca aagcaatcgt tccatgtttc aattcgccag cggcaaaacc ttctgcctgg
    10141 atataactga tttctttcaa tttcaaagca gcttcaagag aaacgttgta gtcagcacca
    10201 cgtccaatgt aaaaggcatt tcttgtatcg ctgagatata cttctgccaa ctcttctaaa
    10261 taatcttttt gggcgatgac cgattccatc gcattagcaa ctaaactcaa ttcatgagtg
    10321 atatcgaata caagagaagt ttcaaattct tttttatcac cgatagcttt ggctaataaa
    10381 gttagtacag ctatttgtgc agtataagct ttcgttgatg ctactgcgat ttcgggtcca
    10441 gcatgcaata gcagtgtaaa ggatgcttcc cgcgaaagag tagaaccagc aacatttgta
    10501 atcgtaagtg aagggtagcc gagacggttg atttttacca gcacttggcg gctgtctgct
    10561 gtttcgccac tttgactcaa gaaaataaag aatggttttt ttgaaagaag aggtgtgtta
    10621 tagccaaatt cactggctaa atgaacctca acaggaatct gtgtcaattt ttccaaagtc
    10681 tgtttacctg ctaaccccgc atggtaacta gttccgcaag caacgatata gattcgatcg
    10741 ctatcagaca atgtatcgac cagcttttga tcaagagaga cacgattgtc ttctgttacg
    10801 tatttttgag cgatacgacg catgataata ggctgttcgt cgatttcttt cagcatataa
    10861 aaaggatagg tacctttctc gatatctgaa gcatctactt gtgcttcgaa tgaagaacgt
    10921 tctacgatgt cacctgcaaa attttgaata ataacttttt ctgatgtgac ggtaaccatc
    10981 tcttcatctt caatctcaac gaattccttc gtatgagcaa gcatagccat tgcatcgctg
    11041 gcaatcacat tgaatccatc gccgagtccg attaatagtg gacttttatt tttagcgacg
    11101 taaataacat caggtgctgt ccgatcaatc aaagcgaaag cgtaagaacc tttgatgacc
    11161 cgcaaagctt ttaaaaacgc ctcttgcgtt gtagtatcct tcgcgaaagt ttcaattaga
    11221 tgagcgataa tctcagtatc ggtctcacca ataaagtggt catttgctaa ataagcaatt
    11281 ttaagttctt caaagttttc gattacgccg ttgtgaacga gcacgaagcg tccactttgg
    11341 gaagtatgtg gatgggcgtt ttcttcagaa ggttgcccgt gagttgccca tcgtgtatga
    11401 ccaataccta tatttcctgt agtatcaata tttattttgt ttttcaaatt ttgaattctg
    11461 ccttgtgctt tgaccagata atcagttgtg ccatctgaga caaagatacc agctgaatca
    11521 taaccacggt attctaattt ttctagaccg tcaatcaatc ctggtgttac attttttaat
    11581 ccaatcattc caacaattcc gcacataaaa aacatcctac tttctataat gaattcgtat
    11641 gaatgcttcc agctgcagga aaatcctttt gttttatctt tgcagacatt ttttgtggat
    11701 tttctgtaga gtgcagtccc tagggccatc cgccgaatct ttcgataaac cctctcctcg
    11761 tcatctgttt acacagacct ggcgctatcc taaaaggtat aactatcctc ctttttgttt
    11821 tttatctgga aacatttaaa atcataacct tttgcgaatg ttcttgtcaa caaaaaaaga
    11881 ataaaaaata aattggtata tatcaaattc tttgtcaaat gtccttttta tgtcaaaaaa
    11941 taatgggttt ttatctatca tctttttcag gagttcggta caatagaaag taatcggata
    12001 gaggaggagt aaaaatggat tcaaaaattg agatcatgac actgggaatg ttaaaaaaac
    12061 aattgtccaa attcgaagca tcagctggtg tatcagatga tacgaaaata tttttagata
    12121 ctggctggga tagcatccaa gaaatcgcac ctgatgcctt ggaagttgct caagctcgtg
    12181 agtttacggt agaagatgaa ttaacaaaag agtcgttttc cgggtatgcg cgggaagaaa
    12241 aagcagagcg gttcgacact tctgagcagt cagaaactgt gatcgtcata aaaaacttgt
    12301 attagaaagg agaaagaatg aataaaagac gttgggcagc agttctgatt gctgcaggat
    12361 tatttgtggt ttcgttagtt tcagctagtt tgactaagcc tcaggaaaac gatcaaattg
    12421 agggattgaa cagttggtta tatggggatg aagaactagc tccaaatgtg ttggaagagg
    12481 gagacagtac gcaaaaaatc gtaaaattat cagtagatgg aacgattgct gcgggagggt
    12541 cttcaggttt atttgcttct gaaggttaca atcataaaaa ttttatggaa caactgaagg
    12601 cgattgaaga agatccaaca gtcaaaggta tctttttaga agtaaattct cctggtggcg
    12661 gtgtctacga aagtgcggaa atcgctaaga aattggatac gattcgtaaa gaacatgata
    12721 tcccaatgta tgtcagcatg aaaaacatgg cagctagcgg tggctactat atttctgctc
    12781 aagcagataa aatctttgca acagaagaaa cagtgaccgg ctcaattggt gtgatcatgt
    12841 caggattgaa ttattcagga cttctagaaa aactgggtgt ggaagataca acagttaaaa
    12901 gcggagcgtt gaaagatatg ggttcaggaa cgcgaccaga gacaaaagaa gaagaagcgg
    12961 tgcttcaagc atatatcgac agcgcatata gtcgttttgt agcaatcgtc agcgagggac
    13021 ggaataaatc tgaagaagaa gtcaaaaaaa ttgctgatgg aaggatttat gatggtgtcc
    13081 aagcaaaaga agtaggttta gtcgatgaat tgggatttcc tgaagatgct ttaaaagcta
    13141 tacgaaagga acaacagctt gaagatgcgg aactagtaga atattcttcc acgccatctg
    13201 ggtttgctag tacatggtta ggaagtaaac tagcagaatt ccagggattg aagccttctg
    13261 agactagtca gatcttatcc gttcttgaga atctagggac agcggaatca ccaaaagcaa
    13321 tgtattatta cggaggtgag taagcatgtc agagctttca aatgaaaata aggaacaaga
    13381 aaaagataag caacagcagc ctgctgtagg acctgactcc aacttttccc aaaaggtact
    13441 gagctctttt gaaagagagc ctttgacgcc cgaagaaatc aaaaagaaac aacgtaaatg
    13501 gaaaaagtat acggacacaa gaaatgaacc gccaaaagca aatgattttc ctaagtattt
    13561 ctatgcaggt ttttttatcc gaatgtttgc cttcttggtc gatcttttgt gtatcggagc
    13621 tattacgcgt ttaacacttg gtattgccaa aaatctaggt tggcttaatt tttcagattc
    13681 ttatctgagt ctctacggat tcacagcctt acttatttat ctagcgtatt ttattttatt
    13741 gacgaaattc aatcatggcc aaacgattgg gaaaatgatc tttggtattc gagtcatcag
    13801 ctttgatgaa gaagaactta gctggtcaac cgttttagtt agagaaggtg cttgccggtt
    13861 cattctaaaa tttcctttgc tgatgttagg gtatcttcca gcagtcttta atcagaaaaa
    13921 gcaacatctg ggcgattttt tcactaatac aagtgttgtt acgatcaatc tgatcaaagc
    13981 gttcaaccag gaagtcaaca gctgatgagc aataaaaagc agtaacagtt gaaagcacct
    14041 tctaaaagtc agatctaaaa tctagctttt agagggtgct tcagttattt ttaattgtca
    14101 tgcttttttt gttttgctac tattgaacat gagctgaata tgagcaagag gaggacactg
    14161 cgtgaagccg attgattttc cagaaaaata tgagaattta atgcgagtgg cacaacaagc
    14221 actagcaaac cagcaatatc agcaggcaaa agaattattt caacgagctt acgagttgaa
    14281 agaaagcttt gaggctaata gcctgcttgt tttttgtctt tacgagttgg acgagaaaaa
    14341 agaagcattg aagcaagcac tcttgcatga aaaacagtat cttcaaaatg aggagtttgc
    14401 tgaattttat tttgacttgt taatcagtac acaagatttt ttatatgcta gaaaattgat
    14461 agcaagtaca gatttttatg aagctttcga gcagcgggtc attgaaaaaa tccaatttgc
    14521 agaagaatta tccggacaaa tggagaggca gaagatcaag gcactccaca ataaatcgga
    14581 ggaacttcct tcgttggaac ctgcacgtca gcttgcgtct attgatgaga tcgaacagct
    14641 tccttatcat gagtttatcc aaacagcgag taaacttatt gtatcgccag aggtccatat
    14701 tttagcaagg gcaaaattac tggagacact taggcaattg aacgaatgcc atcctgtttt
    14761 ctatttgacg attgaagaaa agttagtcaa agtcatacca aaagatctgc caaagccgca
    14821 gcagcaggca agttaccagc aattatgtgt attttcagat cgttacggga atgaagatgc
    14881 gctgcttagt tccgtgttaa aagaagaatt cacgttgcaa tctgcaattg tttatcctgt
    14941 ctatgataca tacatcgaag acccgaagcg ctggtttcaa ctgactgtag aggcgtgtac
    15001 aggaaaaacg atgtatgaag gtacagaaga tgaaaaacaa gattttttaa aaaaaagaga
    15061 aaaaattttg cagcaaatga tcttcttcca ttagatttta tcagtgaaaa agataaaaat
    15121 gttatgaaaa acaaggattc tatccattca atatgtttac aatttgaaag ggttagtgta
    15181 ctatttaaag gtatgcatga aacgtttttg atgtataaaa tgaatttcta aactcggagg
    15241 gaattaaatg actgcaacat ttgaaaaaaa aggcacgaat gatggtgttt taaaatttac
    15301 gattgcgcaa gacgaaatcc aaaaaggatt aacaactgcg tttaataaag tgaaaaaaag
    15361 cttgaacgta cctggattcc gtaaagggaa agtttctcgt caagtattca accgtatgta
    15421 cggtgaagaa gctttatatg aagatgcatt gaatgctgta ttaccagaag cttatgaagc
    15481 tgctgtcaaa gaagctggca tcgatcctgt ttctcaacca aaaatcgatg ttgaaagcat
    15541 ggaaaaaggt caagactggg taatcactgc tgaagtaaca gtgaaaccag aagtaaaatt
    15601 aggacaatat aaagatctag ttgttgaaaa acaagaccgt gaagtaacag atgctgacgt
    15661 ggatgcacgt atcaaacgtg aacaagaagc acaagctgaa ttagttatca aagaagatgc
    15721 tgcagctgaa aatggcgata cagtagtaat cgacttcgaa ggctttgtag atggcgaagc
    15781 gtttgatggc ggaaaaggcg aaaattactc acttgaatta ggttcaggct cattcattcc
    15841 aggttttgaa gatcaattag ttggtcataa atcaggtgaa agtctagatg taaatgtaac
    15901 tttcccagaa gattatcaag cagaagatct tgctggaaaa gaagcagtct tcaaagtgac
    15961 aatccatgaa gtaaaagcaa aagaagtgcc tgaattagat gacgaattcg caaaagatgt
    16021 tgatgacgaa gtatcaacat tagacgaatt gaaagaaaaa tatcgcaaag aattagtaga
    16081 aacaaaagaa aaagcagcgg acgatgcaaa agatgaagca gcgatccgta tggctgttga
    16141 aaacgcagaa atcgttgaat tgccacacgt gatggttcat gatgaagtac atcgttcaat
    16201 ggacgaattc ttgaacaaca tgcaacgtca aggtatctct cctgaaatgt actatcaatt
    16261 aactggttct acagaagaag acttgcataa acaattcgaa ggtgaagcag aaatgcgcac
    16321 aagaacaaat cttgtgatcg aagcaattgc agctgctgaa aatcttcaag caacagaaga
    16381 agaaatcaat gcagaaatcc aagaattatc agaaacatac aacatgccaa tcgaacaaat
    16441 caaacgcgtg ttgacagaag atatgctgga acatgatgtg acaatgaaaa aagcaatcga
    16501 attgatcaca ggtacagcga cagaagcgaa agaatagaaa tcaagtaata aatcatttct
    16561 gaagaagcta cttctagaaa attgtttatt cgaaataagg gactgtgaca cgattttgtc
    16621 acagttcctt attttttgtt aagagtaaaa aatgcaaagg tataggtcag ttgatccttt
    16681 gttaaacact ttttcttttt actaaactat gttatgatag taaaagactg taaagtcttt
    16741 gatagtttct tgcatacttt ttgcaagtta aggggtgaag accatgtatg acaatccaag
    16801 tagcaatgag accgtacgct gttctttttg cgggaaaacc caagaagaag tgaaaaagat
    16861 cgtagctggt ccaggggtct acatctgtaa tgaatgtatc gacctatgta aagaaatcat
    16921 tgatgaagaa ttttatgaag aagctgtacg cgaattcact gaagtcccta aaccactaga
    16981 aattcttgaa gtattgaata actacgtgat tggacaagat cgcgcaaaac gctcgttagc
    17041 tgttgccgta tacaatcact ataaacgtgt caatcagcaa gcacaagaaa acacagatga
    17101 tgttgaactg caaaaaagca atatctgctt gatcggacct acagggtctg gtaaaacatt
    17161 tttagcacaa acattagcaa aaacattgaa tgtacctttt gcaatcgcag atgcgacaag
    17221 tttgacagaa gctggttatg tgggggaaga tgtagaaaac attttgctta aattgcttca
    17281 atctgctgat tacaatgtgg aacttgcaga aaaagggatc atctatattg atgagatcga
    17341 taaaattgcg cgtaaaagcg aaaatgtatc tattactcgt gacgtttccg gcgaaggtgt
    17401 ccaacaagcc ttgctgaaaa ttctagaagg aactgttgca agtgtgccac ctcagggcgg
    17461 acgtaaacat ccacatcaag aatttattca gattgatacg acgaacatat tgttcatcgt
    17521 aggtggtgca tttgatggca tcgaaacgat tgtgaagaat cgtatgggcg aaaagacgat
    17581 tggatttggt acacaaaacc aaaaactttc tgaagacgaa agtgtcatgc agcatatcat
    17641 tcctgaagat ttactaaaat tcggattgat ccctgagttt atcggacgat tacctgttat
    17701 ggcagcttta gagaaattga caacagatga tctggtacgg atcttgactg agccgaaaaa
    17761 tgcgctagtc aaacaatatc aaaaacttct ttctctagat aataccgaac ttgaattcga
    17821 acctgaagcg ttgagagcca ttgcgaaaaa agcaatcgaa cgcaataccg gtgctcgagg
    17881 acttcgttcc atcattgaag aaatcatgat ggatgtgatg tttgatatcc cttcaaatga
    17941 aaacatcgaa aaagtgatta tcacaaaaga agcagctgaa ttgtctggtg agccaacagt
    18001 aatctataaa gattcagaga aaaaagcggg ttgatgaaaa gaggctgccg taaaagtcat
    18061 tttggctttt gcgacagccg cttgctttat tcatcacctt gttaaggaga gagaccatga
    18121 aagtccatca agctgaaatt atcataagtg cagtggcacc aaaacaatat ccagatacac
    18181 aattgccaga aatagctctg gcaggacgat caaatgtagg gaaatcttct tttatcaaca
    18241 cattgattga tcgaaagaat ttagcccgta cttccggtaa gccaggaaag acccagacat
    18301 tgaattttta tttgatcgag aacgcattac attttgtcga tgttccggga tatgggtatg
    18361 caaaagtatc caaaactgag cgagcaaaat ggggaaagat gatcgagaca tatttaacga
    18421 ctagagacca gctacgtgcg gtcgtttctt tagtagattt gcgtcataag ccttctcaag
    18481 aagatatcca gatgtatcaa tttttgaagt attatgatat ccctgtaatt gttgttgcca
    18541 ctaaggcaga taagatccct cgtggtaaat ggaacaagca tgagagcgaa atcaaaaaag
    18601 cgttggattt tgatcgcaat gacacgttta ttctcttttc ttccgttaca aaacagggaa
    18661 aagaagaagc gtgggcagca atcgaacaag caattgaatc ataaaaagaa taaaaaagac
    18721 ttaccagtca aactctttca taaaagtttg gctggtaagt ctttttttga gcttaactta
    18781 cttttgtttc ttgtcttttt tcttttcatt ttgtggctgt ggttttagaa atcgatcgat
    18841 ctcttctttt ggtgcaactg ttttttccgg atcgacagca aatgattcga aaagtttatc
    18901 taaattatct gtacgttcaa atttcaaccc cattgtaaac acctctttgt ttctttttac
    18961 ttagtctatc atgtaatcgt ccaaattggt ttctaagaca taaagtttta gtttttcttt
    19021 atcattggtt ataattaaat tataaaaaga tttgaaagag gtgagaaaat gattggcgaa
    19081 gataaattat tgatgactat ccagctcaca gacttaaatg aagaagaaaa aaaacaggaa
    19141 ataagcgatt gggctatttt gacacgtctg ttgatccagc caacatttat ccgctctttc
    19201 acacaacaag cggatccgta tgatcttcga aagcttcaag aaaaaataat gctagcatcg
    19261 gtaagagacg aaagttggtt agttgtagga aatgacgaga acgaatgtag ttttcgcttg
    19321 gaagataatc aattattgat aaaaaatgta ttgtctatct ctgttttcaa agaaaagcaa
    19381 tttttgattc gagacttcat tcagaaaaaa atgattgctc atggggtgtt cgcctatatg
    19441 cgagcttata gcgagtttat ctatcacaat acaaaacaga tctctcaacg gctattgttt
    19501 gagaaaaagg atgaaatcga acatttacct aaaatgaaac aacaaaacgg ggaagtagta
    19561 gtcgattgca accaatttcc aggatacgat cttttttacc aaggtttatg tttcacttcg
    19621 tgttgggaaa tgtattatag tcgctattat catcaaatca tccctaaacc gatttttctc
    19681 gacatccaac aagtagaaaa agtgaaggaa ttagaaaacg aagtcatatg tatccagctt
    19741 tatcgagacc cctttaactg gcaaaagcca aacaatcaaa tgtttcaatc ctattttagg
    19801 gaccagcttg ggtttgatca tcttgcttgg gacaatggtg tcggtttatt gaaaccgcca
    19861 ttcgttgaat acatttacac tgaccatacg atccaatctg tccagtatca gaatgcacaa
    19921 atgcaacctg ttcctaaaaa gaatgcttca ttttttgtaa caaaaagtta tgatatccaa
    19981 caaggagatt ataaagaaag gcgtgttcgc ggaacactaa atgctcaggc gtattttcct
    20041 tgggttgacg agaatcgatc acgcatgatg tgctataaag ttatcgatcc gactgttgct
    20101 ttggataatg gaatcgaagc ttattgttat tatattaggg aatatctaga agtagaggta
    20161 acagatgaaa aatatcaaga gtatctttta tccttaagaa tctatgttcc ttcagaatcc
    20221 ctgtcagaat taccgttaaa ggaaatcaaa catagactct ctgatgttac cttcaaacga
    20281 ataaagaaaa agcggcgaag tatccaattc gatgtcaaga aaggtgagca gcatctgcgt
    20341 gtgcaatttt tagattaccg agaattagaa caattgatta ctttacaaaa aatatgaggt
    20401 gaagaaaatg gataaacaac tctattatcg aataatggtt ccggcatcat tattatccgt
    20461 ctgtctcttt tttgttccta attttcctat tcgatcagtc atcggttttt tggtcatgtt
    20521 tggcgggatg ggactttatt attatcttct tcataaggaa agaaaacctg cttctgttta
    20581 tatgaaaaaa acaagaagcg aaaataaaaa acgataaaac ggcttgatga tagacaaaaa
    20641 aataaaaaac cagtctttct gac
//
LOCUS       DAXLPY010000050        19694 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.050, whole genome shotgun sequence.
ACCESSION   DAXLPY010000050 DAXLPY010000000
VERSION     DAXLPY010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.050"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(65..265)
                     /locus_tag="ACF3UF_001897"
     CDS             complement(65..265)
                     /locus_tag="ACF3UF_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3671998.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(717..1037)
                     /locus_tag="ACF3UF_001898"
     CDS             complement(717..1037)
                     /locus_tag="ACF3UF_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3671999.1"
                     /translation="MKKRVLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(1540..2658)
                     /locus_tag="ACF3UF_001899"
     CDS             complement(1540..2658)
                     /locus_tag="ACF3UF_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672000.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPEIEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            2891..3013
                     /locus_tag="ACF3UF_001900"
     CDS             2891..3013
                     /locus_tag="ACF3UF_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672001.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            3129..4436
                     /locus_tag="ACF3UF_001901"
     CDS             3129..4436
                     /locus_tag="ACF3UF_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFD3672002.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGESRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANMFVIGWRRVAEFFGNLF"
     gene            4555..5754
                     /locus_tag="ACF3UF_001902"
     CDS             4555..5754
                     /locus_tag="ACF3UF_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFD3672003.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(5781..7049)
                     /locus_tag="ACF3UF_001903"
     CDS             complement(5781..7049)
                     /locus_tag="ACF3UF_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFD3672004.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKAEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(7104..7170)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(7212..7859)
                     /locus_tag="ACF3UF_001904"
     CDS             complement(7212..7859)
                     /locus_tag="ACF3UF_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HFD3672005.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(8267..8770)
                     /locus_tag="ACF3UF_001905"
     CDS             complement(8267..8770)
                     /locus_tag="ACF3UF_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3672006.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(8893..9657)
                     /locus_tag="ACF3UF_001906"
     CDS             complement(8893..9657)
                     /locus_tag="ACF3UF_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFD3672007.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMALTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFMVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKENAESLNVGVAAGIVLYHFSL"
     gene            9765..10040
                     /locus_tag="ACF3UF_001907"
     CDS             9765..10040
                     /locus_tag="ACF3UF_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFD3672008.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEEDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            10717..11667
                     /gene="yidC"
                     /locus_tag="ACF3UF_001908"
     CDS             10717..11667
                     /gene="yidC"
                     /locus_tag="ACF3UF_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFD3672009.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(11846..12820)
                     /gene="lacD"
                     /locus_tag="ACF3UF_001909"
     CDS             complement(11846..12820)
                     /gene="lacD"
                     /locus_tag="ACF3UF_001909"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFD3672010.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(12817..13275)
                     /locus_tag="ACF3UF_001910"
     CDS             complement(12817..13275)
                     /locus_tag="ACF3UF_001910"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFD3672011.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKDVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTKIATILTKEIGEDL"
     gene            complement(13272..14738)
                     /locus_tag="ACF3UF_001911"
     CDS             complement(13272..14738)
                     /locus_tag="ACF3UF_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFD3672012.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDASMGMMVPVLAAYIAEGIAKRPGLIVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDDSKAANRTVIEKGRAGDLS"
     gene            complement(14720..15670)
                     /gene="pfkB"
                     /locus_tag="ACF3UF_001912"
     CDS             complement(14720..15670)
                     /gene="pfkB"
                     /locus_tag="ACF3UF_001912"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFD3672013.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIREERFERWENIN"
     gene            15813..16562
                     /locus_tag="ACF3UF_001913"
     CDS             15813..16562
                     /locus_tag="ACF3UF_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3672014.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINVLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISQKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
     gene            16828..18306
                     /locus_tag="ACF3UF_001914"
     CDS             16828..18306
                     /locus_tag="ACF3UF_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFD3672015.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(18374..19465)
                     /locus_tag="ACF3UF_001915"
     CDS             complement(18374..19465)
                     /locus_tag="ACF3UF_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFD3672016.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT         6082 a         4031 c         3410 g         6171 t
ORIGIN      
        1 agaaaataga caaaaacgcc cagacacgca aatgtctggg cgtttatttt ttagtatagg
       61 ttaattaagc tttagtaacg tttgttgctt gaggtccgcg ttggccttct tcaacatcga
      121 aagttactgc ttggccttct tctaaagttt tgaatccgtc gccttggata gctgagaaat
      181 gaacgaatac atcgtttccg ttttctgcag tgatgaatcc aaatcctttt tctgagttaa
      241 accattttac tgtacctgtt tccataataa aaatcctcct tgtgtatcaa cacatatttt
      301 gcaattactt gaatggtgta tatctggaag atgtttattt gaaacaagct accacagatt
      361 accgaacaaa aactactcct atagtatatc ataccgttta caaaaaagct agagtttttc
      421 gacttttttt attaaaaaaa gttttctcag cgattacata aagtgaaaaa ccgaactttt
      481 tttaaaataa acgaaatatt gttcagttgg tgtttttttg ctctgatgtt cttctttaaa
      541 ctaaaaaaat tattctttct gactacttat cggttctgtt tcaacggtcg aggctgggga
      601 agattcttta gtaggtctga tgttctcatg gtatttctga tagcctatga cagtgaccag
      661 aagaacaagg caaaccaata cgatcaacga gattagtttt tcttttttgc tcatatctat
      721 acctcataaa taacaggatg atgtccatca tatttctgag tatgagtaaa agcaaaagct
      781 gcagctgtag aatgtaagaa atgccagcaa ctttcataat cacaggtcgg acagtaccaa
      841 aagtaaccaa atcttggctg caaagaccgt tcttctgttt caggaatcgc agaatcaaga
      901 tctgttgtct gtacataaac atttttgtac agacgtgtgc ctgtaatagg agaccgctgt
      961 gtttcttcag caaaaactgg ctgacttgtt aaacttaggg atagaaacag caaacaccat
     1021 aacactcttt ttttcataaa gacctcctta tcgataagtt tttcccaatt aaaatcatat
     1081 ctcaagaacg cccgttattc acattttgtt cataaatgat gttttttgta tcataatcgt
     1141 caaaaagagg tcgtgaccac gtcacaacct cttttttaaa tggtgttcca gaagtagctt
     1201 cttcggaaat aagccgaaat ttcacaaaaa tttgagaaat aatttttgtc aatctcttct
     1261 tatttcttga agctgaccac ttctgtcaca acctcttcct taaacggtgt tcaaaagctt
     1321 gcatctgcgg taataagccc accaaacaaa aaatatgaag agctattttt gcttgctgtt
     1381 cttattactt gatgcagaac agctttttca caacctctca tacacggtgt ttaatcagct
     1441 gaccttcggt attagctcaa aaaacggcaa aatatgtgaa actatttttc cgtttgtttc
     1501 tctaatactc aggtcaaaac actgttttca caacctcttt taataacgaa gaatcgctgt
     1561 cagactcttt tcatctggcg catctttttg atccaaaata aacactttcc cgccattaat
     1621 gatcacatca tctgctaatg cattcaacac ttgacgccga tcatattcta tttcaggatc
     1681 ttcaccgaaa ccatcagcta agtttgacgt agcgataaat agatgcgaca cttttccttc
     1741 tttcgcagct ggaacgatat caactaactg atcgatgaat ttcttatcta agagtttatt
     1801 gtattctttt gattcttgag ctgcgagttc acttgacagc ttcttcgccc cttcttcgat
     1861 atctctaaag gatagctgcg caggagaagc agaaatcgca acgtctgcac aataataggg
     1921 atttttagca atttttttga acatcgtctg attttctggt aatgcaaata aataaatcgg
     1981 ccattgttct ggattttcga aagaatcctt caagtacgta tcaacagctt ggtaatagtt
     2041 gacccaatcg atctctactt cttcatcttt tggatttacg ccatggaaag ttactccatc
     2101 tcgggctccg cctcctccat tagaagagaa gttcaaaccg ccacctgtca gttcagatcc
     2161 caatgcagta acgacatcaa ccggtgcccc ttctggtaga gatacttctt ttacttgttt
     2221 gttgctgact tcatacaatt tcatggagtc gcggttcaat cccaacagat aataggaata
     2281 gttgaactgt ccatttttga taatggccag taaataagga agatcactta catagtattg
     2341 atcgtctacc gggatactca aacgatggat ataggtttgg tcagcagtta taatgaccgc
     2401 tacactcgta gttgcactac gccaaaacga aggatctcct aacaaatttt caattttttc
     2461 ttggaacggg gaccagtcat gttcggaata ttttttctca aaacgtttct ttgcttcttt
     2521 cgcaaaattt ttgaatttga tttgatcttt ttccacatct tgatgggcga catgcgtatt
     2581 cagcatgatc gtgacgaatg gtcctttagc gccttctgaa gtcaattgtg acaataattc
     2641 tttatccttt tttgccataa acgtacccct cctaaaaaaa tcattccttt gtttctatct
     2701 aaagtctacc acaacactat ttttccatac aataaaacgt atctaaaaaa ataaaacggt
     2761 ttctacggtt ttaaatttag ctattttttt aagttatctt cataatttcc tcaattattt
     2821 agccccagtc ttcaactatt cttcatgaaa tgctgataaa ctaaaaaaaa gaataaaaga
     2881 ggtggatctt atgcatttga ttatgatttt cagtttatta agtattatca gtttatttgc
     2941 tttcagcgct tcccgcttat tagatgcgga aacacagcct attcctgtaa aagtacgtaa
     3001 aaacgaccgc taaccttcca taacgtgcgt tcttatccta aagttttttc agaaacattg
     3061 aaactctctc ccctctctga taaaatttta atttgtagcg aaacaaatta attacaagga
     3121 gatcggatat gtccataaaa aaaacacgtc tagtcctatt attggctagt ctcattcttt
     3181 gccttgcttc ttttctacca gctgttgctg tgcaagctga agatacgttc aaagtaaatg
     3241 caaaagcagc ttttgctgta gatgcgcaaa gcggtaagat tctttatgat caagatggag
     3301 aaaaaaccat ggggatcgct tcaatcacaa aaatcatcgg tctttacatc gttcttgatc
     3361 aagtaaaaga aggaaaacta tcatgggatg ataaagtttc gatttcagat tatgcagaaa
     3421 atttgagtat caccccagat ttatcgaatg ttcctttgca taaagaaaac acctacactg
     3481 tcaaagaatt attcgactct gcaatcatcc agtcagccaa tgcttcaatg gtggccttgg
     3541 cagaaaaaat ctctggcagc gaagctaaat tcactgaacg aatgaaagaa caattgaaag
     3601 attggggaat caaagatgca acgatcgtta atgcatcagg actgaataac tcttatcttg
     3661 gcgaaagccg accagaaggt actggagaaa acgacgaaaa tcaaatgtct gctcaagatg
     3721 tggccatcgt ggcccgtcat ttgatcttgg attttccaga aatactggac gtatctagca
     3781 ctacgacaca aatgtttggc gaaaacacgc aatcaccagt ggaaatggtc aactggaact
     3841 ggatgctccc aggattcgtt aattacaagg aaggcgtgga cggattaaaa actggtacga
     3901 ctgagcttgc aggtgcttgt ttcgttggta cgatcactaa aaacgatcaa cggatcatca
     3961 ctgtcgtatt gaatgcggac ggccatgcgg aaaacccgag tgcccgcttc aatgaaacag
     4021 accgtttgat ggactactgc tatgacaatt ggtcagaaaa agagctcgga aaagctaacg
     4081 caagtattcc tagcctaaaa accattgatg taaaagacgg aaaagaatca acagttcctg
     4141 ttgtgcttaa aagccctgta aaagtatggg tacgaaacga tatggatact ggcaaattaa
     4201 cgatcacgcc aacacttgac aagaagcaag tcactgacaa cgagatccaa gcacctatgg
     4261 ataaaggtac aaaaatcggt accgctacga tcaccttggc agacgataaa ttaggctatt
     4321 tagaagacaa caatgcgcca tcaacagaga tcattacgga taaaacagtg gaaaaagcga
     4381 atatgttcgt gattggctgg cgacgcgtcg cagaattttt cggcaacttg ttttaattga
     4441 acaataagaa aagcatcttt ccatcggaaa gatgtttttt tgctttttct agtttaaata
     4501 acagcttttt tcatctattt tcgttatact gtataagaaa aaggagttga atttatgaat
     4561 ctaaccagag atctgatctt tttagttctc tatcttattg gggtattctc tatcgtttat
     4621 tggcgaaaac agaagaagga tccttccttg ttcttttacg gcagtacgtg gacatttacg
     4681 gtaatcttaa cttattttgt cgtgttggaa attttttatt cgacctttta ttttttgatt
     4741 ccattgttgt tctttagtat ctttgctttt tcttatttca cagaaaaacg aaggctgctg
     4801 aatggtcttt tattcaatgt tttcctcatc agtttcggca tctacttgtt tgtcttgctg
     4861 tatgaaacgc aaaatatttt ccttggcgga ctgatcgcct tgatcacgat tccattgcta
     4921 cttgtccttt tatttggtat ttatggattg attgtttttc ttttttggaa cggggtcaca
     4981 gttttacgta gagaatcgca ttcattagcg aatcttttaa cgttgatact agccattttt
     5041 cttacactgt ttcttgtttt tgactttttc ttgttaaaat atttgccgca atggataaat
     5101 gctttgtttt tctgcgttcc cctgatcttg atctatctat ttatcgtatt ctacaacttt
     5161 ttgactgtct cattcttgta ccagttcaac cggcctcgat acaatcaaga cttcatcgtt
     5221 gtgttaggcg ctgggttgat caatggagaa acagtttctc ctcttctagc caagcgaatc
     5281 aataaggcaa ttgcttttta tcgggctcaa agccgtgcta cattaaatcc gcccatctta
     5341 ttgatgtctg gcgggcaagg agcagacgaa aaagtaccag aggccattgc gatgaaacaa
     5401 tatgccatgg aacaaggaat ccctgaaaga gacattcttg tcgaaaccaa ttcgacaacc
     5461 actttggaga acatgctcta ttcaaaggaa atcatggatc agcaaatgaa agggccatac
     5521 cgcgcgatct ttagttccaa caattaccac atttttagag ccggtcttta tgcgcggcaa
     5581 gccaaattga aagcaaatgg tattggtgca aaaacagctt tctactactt gcctaatgcg
     5641 tttttaagag aatacatcgc catcttgatg atgaacaaaa aaagacatat gatcatttgc
     5701 ggattgcttt tcgcaggctc cgcattctta tcgctgatta ctttactttt ctaaaaaaac
     5761 aaggtgtgac aaaacatatg tcacaccttg tttttttctt tcattctctt aactattggc
     5821 aaaaagagta tccctttttt gaccgctact tgctgagcag aataaatacc gctgttgcct
     5881 gaacacataa agctgatcaa gcagatcata aagaagtaaa cagccgcttg tgaaccgaac
     5941 aattcgatcc ccatcacaaa gcaggcaatc ggtgtatttg tcgcaccaga aaatactccg
     6001 ataaagccca atcctgcgag aaaaggaaca gaaacatgga gcaaaggcgc tagtgctgca
     6061 ccaagcgttg caccaatttc aaacaatggt gtcacttctc ccccttgata tcccgcgcct
     6121 aaagacaaaa ctgtgaagaa taacttccca ataaaatcat agacatgtgc ctgtccatta
     6181 aatgattctt gaagtaacgg aagactcaat ccgagataac gttgtgtttg caaaatcaat
     6241 gctgctgcca caactacagc cccacctatc gtatttcgcc aaacaggatg aggaatccat
     6301 tgtgcatacc gtgcttttaa aaagacgatc gaacggctga atacccagcc aatcaaacca
     6361 aaagcaatcc cagcaacaaa aactttgaag aacagcaaca tactccattc agggatcaca
     6421 cccatttggt aatgtaggtg agaaacacca tagctttccg tcatgaaatt tgcaaacagt
     6481 gcagcaaaga agctagggaa gatcgcttct gttcggactt tcccgattgc caacacttct
     6541 aatccaaata atgttccagc taaaggtgtg ccaaatacag aactaaaacc cgcactgatt
     6601 ccactgataa tcaagatttc ccgttctgct ttatccaatc ggaacaaacg tgctgtatta
     6661 tctgctaacg ctccccccat ttggactgct gttccttcac ggccaacaga tcccccaaat
     6721 aaatgggtag ttatggttcc aaacagtgta agtggaataa gccgcaacgg gattttttct
     6781 tctccaccat ttccttgatc gatcactaag ttgtttccac gactagaaag tccgccgtga
     6841 tacgcataga gataagcaaa aagcgcacca ctaactggta gtagataaag gagccaagga
     6901 tgtgatagtc ggatatctgt cacaactgtc aagctattta agaaaaaagc agacaagctc
     6961 cccatgaata taccgagaat cgctgtgatc accagccact tcagcatgta cactaaaatg
     7021 cgtactggac tcggtaattg tttttccata aaaaattcct cctcaataaa aaaacgccta
     7081 ctaaagaaag gggctatccc cagactttag taggcgtcat tagctatctt tcgttagcat
     7141 ttaaaggcga acaccatcac ctattcactt ccattaaaag atagcatatt tttctgtaaa
     7201 aaacaataaa attatcgttc tttctttaca cgttcagcaa attcatagaa aggagccaat
     7261 ttcgttaact gttgattaca ttggtcacta tcatgacaaa tataattccc ctttttcgta
     7321 tacgtgccat cagaacctgc tttcgttgta gaaagaaaaa gcgaaacatt cgatgttttc
     7381 tgacagattg cacagattcc cttatttatc gttggtgata aagtaccgct aatccctttt
     7441 aatttttcat cttcgtaata gaccatgaat tttttctgcg tacctggatc attccagccg
     7501 atgtacgtat gttcttgcaa gtcgatttca ttccaagctg gttgtttgag ttttttcact
     7561 tttcggaata atttctcgat ttgtggtttg ctaggctgca taaacggctg aacgatttgc
     7621 ttcagctcct ccaatgctct ttctgcttgc gcttttgtca gttttacgtc taaaactgtc
     7681 gttaaaaatg tatcgatttc tggcagttcg tgatctaata tgtctcgaat cttttcagct
     7741 gctagtgcct gaactgtttg caccgttttt ggatcattga cagatgagta cgcatttaat
     7801 aactgttcta cttctctttt tataaaaaaa tattggtatg gttttattgt ttgttccatg
     7861 attttaaagt cctttcttct aaccaaagtg catactttgt agaaaaaagt gatcttctgc
     7921 aaagtatgtg ttacctgaag atcccggact cttttaaata agatacgttt tgcatcttat
     7981 catcaccccc tttaatgctt attcttctat gtacatgatt cattcgataa ataaaagtaa
     8041 accgtatctt gaacagatag tcaactgcaa acagaaaaaa ggactgtgac aaaagtcgtg
     8101 tcaaagtccc ttgtttcgaa tgaatggtgt tcaaaagctt gcatctgcgg taataagccg
     8161 aaacttcaca aaaatttgag aagtaatttt cgtaaattcc ttcttatttc ttgaagctga
     8221 ccacttctgt cacaacctca atatggtcta ttattggttt tacctgttaa atcgaggatt
     8281 ctttcccaaa gtaacgttgc catctcttac gcatacttgc agacatgggc tgtgccgctt
     8341 ctttgactgc gcagtatttg tccacgaatg tcacgatata tccttcttta tacttaggcg
     8401 gtgcgatcgt tgcaccccac atgtgcttca aaatgatatc tcgctcaaga tccgacaaat
     8461 cggtgatttt ttctgcattc tttacagcaa ttcttggatg gatatacgca tgtgtcccct
     8521 cgtcaaattt cgtcgtacgc caatcatagt agaacagatc atgcaaaagt ccagcacgcg
     8581 ctgttgcttt agcattgcca ccccattttt ttgcgagcag ataactatag taagaaacac
     8641 tgatggaatg ctccaaacga gtggaatgaa catgctgtgt gtaattcgct aattttttca
     8701 ctgcttctgt ttctaaaaga tcttgtacat aagacatata ttcttcgtct tcacgccatt
     8761 tttctgtcat aattatcgat ctgccacctt tttgaatttc attttcttct gaaattgatc
     8821 taagtatacc accagtgttc ggattattct agtcgctcta gataaaatag ctaaagctta
     8881 atagttcctt aatcataaag aaaaatgata aagaacgatc cctgctgcga ctccgacatt
     8941 caatgattcc gcattttctt tcattgggat atatacgttc tgatcagtca aagacaagat
     9001 ttcctgactt actccctgac cttcgtttcc catgattata gcgaaatcct ctgttttttc
     9061 tactttgtct aatgcatgtg cttcttcatt taattctgta ccgtacacca taaacccttt
     9121 gcctttcatt acagggatca cttctgccaa atctttttgt aacacaggca aatgataatt
     9181 gcttccctgc atgcttcgca gcacctttgt actataaata tctgccgttc ctttacctaa
     9241 taaaacacca gccataccaa acgcatctgc cgtacggatc atcgttccca catttccagg
     9301 atcctgtaca ttatctagta aaagccagcc tcctgaaaaa tctggcgtat cttcagatgt
     9361 taacgccatc actgctaaga tcccttgcgg tgtaggtaga tctgacatag cggtcatgac
     9421 ctcatctgaa actagaaaag tagaaatctc tttgtttaca gccagccagt ctccccattc
     9481 tttcatacct ctctgtgtca caaaaagttc ttttatttct gcatcagacg acgcagcttc
     9541 ttcgatcaga tggaaccctt ccaaaagata ttctgccttt tcttctctgt atttcttttt
     9601 atgtagtttt tttaattctt tgattcttgg attttttgct gattggatct ctttcacatt
     9661 ccttcacctc acctgattat atcatggaat aggtgcttga gcttgtttca tcctaaaaaa
     9721 atcggtatca ttgatttata aaacaggaaa gaaaggtgac gaacatgcgc aaagttaaaa
     9781 tgaatgtcca aggacgtgtc cagggcgtgg gatttcgcta tatgaccaag atggttgctg
     9841 atcagttagg cgtgaccgga acggtaaaaa acgaagagga cggctcagtc acaatcgaag
     9901 caatcggaaa tgacgacatc atccaaaaat ttatcgaaga agtcaagaag tctccgagcc
     9961 caagtggacg agtgcagtat gtggatgtcc aagaagatcc gatgattgag gaacgaaaga
    10021 aatttgatgt ggtgggataa ggttgtgaaa aggtcgctta gttttgagta ttaaggaaaa
    10081 ttttgtgaaa atgtctttcc acatttttgc ataaatttga cttaataccg agaaactgac
    10141 ttttgaacac cgtcgataag gttgtttttg aagcgctttg cctcgagtat taaggagaaa
    10201 cattttcaaa atagcttctc atattttgaa atgtaatgac ttaataccga gaggcagctg
    10261 ataaaacacc gtcaataagg ttgtgaaaaa gctggtctgc atcaagcatt aaggactggt
    10321 tgtgaaaaat agctctccat atttttcaac aggctggact taatgccgta gatgcaagct
    10381 tttgaacacc atcgataagg ttgtttttga ggcactttgc ctcaagtatt aaagacaggt
    10441 agtaaaaaag ctgatctata acttgcaatg aatttgctta acccatattt tccagacaga
    10501 acaaaaaagt ttttagtttt ttaaataaga aagaaacact tggaatcact cttttctttc
    10561 taagtatttc tttcttgatt ttttgtcttt tttcaaaatt tttcgctacg aaaaagaaag
    10621 aatatttata tgaaatttct atgaagttga ttgaattcca tgcgcttttt tagtatagtt
    10681 aagtttgtgt aaaaattata gaagaggaag tattctatga ataaatggaa aaactggtta
    10741 ttgggatccg gacttgtcag tatcctgctc tttttatctg gctgcgtgcg gatggattca
    10801 aacggaaacc ctgacacttc aggaatcgtt tatcgagtac tcgtccatcc tatgggccaa
    10861 gcgattacat atctagttga gaatttcaat tggtcttacg gctgggcagt tattgcaatg
    10921 actgtgatcg ttcgtatcat catcttgcca ctaggtatca gtcaatcgaa aaaaacaatg
    10981 atccaatctg aaaaaatgca agcgttaaaa ccacaagttg aagcagcaca gcaaaagcta
    11041 aaagctgcaa caacacgtga agaacaaatg gcagcacaag cagaaatgca gcaagtatat
    11101 cgcgaaaacg gattgagtat gaccggcgga atcggctgtc tgcctctatt gatccaaatg
    11161 ccgatcttct ctgccttgta ttttacggct cgctacacag aaggtatccg tgaatcatct
    11221 ttttacggca tcgatctagg ctcaccaagt atggtgcttg ttgccattgc aggggtcgct
    11281 tatctgcttc aaggatatat ttcaacaatc ggtattcctg aagaacagaa aaagacgatg
    11341 cgtacgatgc tgatcgtctc tcctgctatg atcgtcttca tgtcgatcag tgcgccagcc
    11401 ggtgttacac tttactgggt agtcggtggt gtgttcagct gtctgcaaac attcatcaca
    11461 aacgttatga tgaaaccacg tttgaaagca caagtggcag aagagttgaa acaaaacccg
    11521 ccaaaacaag tcgtcactcc aagaaaagac gtgacagaat cagcaaagcc agctaacaac
    11581 aaacaagcaa caaaacaaat caaacaacca aaaaacagta caaacaacaa aggccgcaac
    11641 gcaggaaagc agcagaagcg gaagtagata gtaaataaga gtgtaataaa aattcattaa
    11701 cagttttagc aattaaaaat atcgaccaag atttttgaaa aagaaatctg gtcgatattt
    11761 ttatttaagt gaatgtttaa tttgaatcat cgattgatcg ctatctaatt gcagcagcat
    11821 ctttttatga agaaacaact ttttcttatc tatcaacgta gacaggtgtt gctgtttctt
    11881 ctaatagtgt acttaattcc ttaatatttt gttttccttc ttctaacatc caactactcg
    11941 ctttttcttc gccttcggta acaaaaggcg ccactccctt cgcccatgtt gctcgcccac
    12001 ataagacacc attgaatgtc gaacctgatt gttttgcaaa acgtaatgta tcttgaaata
    12061 gcgtagcatt gactcccgca cttaaaaaaa taaacggttg ttcagtcact ttcgattgtt
    12121 catagaaata cgcggatgcc tctgcttgac tataacaagt ctcttgccca tatccttcca
    12181 caaatctcat attcactggc acttctactt tcaatacatc cacttgataa cgttcttttg
    12241 aaaattctcg catggcttca ataactttat gtggttttac ttttgcatag gcaagagaag
    12301 acggatcgcc aatagttgca tcataagaga ggatctctaa aaagaaaggt atgccttctg
    12361 cttcgcattc tgaaccaatc cgttctataa ctatttgttt ttgcacatta atctctgctg
    12421 gttcatcaac gtcatagtac aataaaaatt tacaagcatc cgcaccagct tcttttaacc
    12481 ttttcaccga ccaaatattc aataaatcag gtaatcttcc cggaattttc gtatcatagc
    12541 cggttttttc ataagctagc agcaagccac attctttctc tcgaagcgct gctgcaggca
    12601 ggccgtattc tggatcaagt aaaatagctg aggcataggg agtcaggtat tgagaaacca
    12661 tctgtttaaa ttggatgatg tcttctgatg tagcttcttt atattggttg atcattttct
    12721 tcaaagcacc acgctggtcg attgctaacg cgctaataat tccagcttca tccgtcaatc
    12781 gcttcaaacg ttcctgcttt tctatactca tcttcttcat agatcttcac ctatttcttt
    12841 agttaatatt gtggctattt ttgtttttga ttttgctttt ctcaactgtt ctgtaacctc
    12901 ttttcgcatc aatgatcgtg caacgagaga caataatttc aaatgagtcg ttcctgcttc
    12961 tgaatctgga ataaataacg caaaaataaa atcaactgac tgtctatcta aactgttcca
    13021 ttcaattcct ttgttcagtg tgacgataat catactaggt tcgttgattg tttgagactt
    13081 cgcatgagga atagcaaaac ctgacattat tcctgtagta ccttcttttt ctctttctag
    13141 aagtttttga tatacatctt tttcgtcatg agcaattcct aagcagaatg tttgctttgc
    13201 taaaaactta aatgcttctt cttgactatc caatggctgt tgtaaaaaaa tgttctcttc
    13261 atgaatgatt gtcatgataa gtctcctgct cttccttttt cgataactgt acgatttgct
    13321 gctttactat catccatctt cttgtcttta tcagttactc ttttcttttg gattaatcct
    13381 agtatcactc caccaacgat cgaaccaata agaatcgctg taacccattg gatttttcct
    13441 gttactacag gtaatactaa aaaaccgcca tgtggtgctg gaacttggac gccaaacaaa
    13501 taagtcaaga cagcagcaat tgatgagcct aacatcatcg tgggtaacac tcggatcggg
    13561 tctttcgcag caaacggaat agctccttcc gtaatatgag ttgatcctaa aataaaatta
    13621 accaaacctg cattacgatc attggtatca aaatatttac caaacaataa agtagcaaaa
    13681 ccagtaatca acggtggcgc aatacaagct gctgacacac cagccataaa agtcgtgttt
    13741 ccttgtgcca aaagagctgt tcctgttaca tatgccgcct tattaaccgg tcctcccata
    13801 tcaaacgcac acatgcagcc aacaatcacg ccaagaacaa gtggattcga atgttcaaat
    13861 ccagctaaaa agctcatcat tccttcattt atagccttca ttggacctgc cagcaaagac
    13921 atcacgatgc caataaatgc tacgccaata actggatata agaagattgc cttcaagcca
    13981 tctagttgtt taggtaaaat tgtcagtagc ttttgcaaaa ataagataaa ataacctgct
    14041 aagaacccag ctaaaatacc tcctaaaaat ccagtaccgc cattcatggc tacgattcca
    14101 ccaacaaatc caacgattaa ccctggacgt ttcgcgatcc cttctgcaat ataagctgct
    14161 aaaactggaa ccatcattcc cattgatgca tcgccaactg cttttaccat tgccgctgta
    14221 gcattgtatt gtgcatgatc tggatcaaaa gaatagattc cccaaacggc aaatgaaata
    14281 gcaatcaata ctccgccagc taccacgaaa ggcaacatat gagagacacc gttcatcaaa
    14341 tttttataga tgctacgacc aaaattagca ccactcatcg cttctggttc taaagtatca
    14401 gcagcttcat tatctgctaa gacagtacct tttcctgcca atgcttcgtc aatcagccgt
    14461 tgtgcatcct tgattcctgt actgacagaa acatcaatga ctcgttttcc cgcaaatctt
    14521 tctgaatgga catctttgtc tgcggcaata atgacagcat ctgcctgttt gatttcttca
    14581 gccgttaatt cattttcgat cccaatttgt ccatgggtct ctactttgat cgtgatgcct
    14641 tttttcctag ctgcttgttc taatgcctct tgcgccatgt aggtatgcgc aattcctgtc
    14701 ggacaaccgg ttgctgcaat tagttgatat tttcccatct ttcgaacctc tcttccctga
    14761 ttttgatttg tttacttaat tcctccacat ctaaaaaatc tgttaatcct ttgcgaaaag
    14821 cggttgagct gcctgctgct atgcttttac gtaacgtttc atcaagcggt cgtcgattca
    14881 tgtatcctgc taaaaaagcg cctaacatgg tatcacctgc acatgctgta ttgacaactt
    14941 ttccttttgg cgagtttcct cgaaacaccc tgtctttcgt aaaaagaatt gctcctttct
    15001 caccgaggga taacaaaaca ttttctgcac ctaactctac tagtcgttgt ccataaacaa
    15061 agtaatcttc atctgtaacc atttttcgtc cgaaccaaga agaaagttct tcctcgttcg
    15121 gtttcagcaa aaatggtcga tagggtaaac aatccatggc ttcttgatca ctactatcaa
    15181 taatcaaatg aatccccttt tcctgacaaa tccgactgat ttctattaaa acctttggag
    15241 acagccctct tggtaaactc ccagaaacac aaagataatc ttctgcttgt aatgctctta
    15301 tttgatttaa aaaattatgg acagctgtct gcggtatttc aggtccttga ttcactaatt
    15361 tgtattcttc tcccgtttga ttgacttgtg taaatacatt gatacgcgtc ataccaggca
    15421 cttcaataaa ctctgtttgg atttgtttct gctgtaaata gtcttctata tactttcctg
    15481 tgaacccagc agaaaaacct aatgccgtac ttgggaaatc tagcatcttt aatactagtg
    15541 acacattcac tccttttccg tttgcctgaa tgtcatcctc ttttgtgcgg tttaccataa
    15601 aaggatgcat ctcctctgtt tcaataaata gatcaattgc caaattcatc gtgcatgtgt
    15661 agatagacat aaccaatgac ctccttgact ctattatgaa atacgcgaaa gagaaaatgt
    15721 tttcttaatc gttccaacac aaagaaaacc tttacattta taaactcgtc gtgctatttt
    15781 ttaactaact tttggtgaaa gaaggaaaga atatggatca caaattaagt gaaacagaac
    15841 agtacctctg gaactttatc gaacaccata tcctagagat ccctaactac tccatcgtga
    15901 aactaagtga acaagcaaat gtctcaacag ccaccattgt gcggacaatg aaaaagaaag
    15961 gctatgaagg gtttacttcg tttaagcatc atctaaaaga aggagaaaac aagaacatca
    16021 atttttcttt cttagataaa gtagacaaag gtatccgccg agccattcta aaaaatgaac
    16081 aagaagtggt acgtacgatc aatgtgttgg aaatcggaaa tattgaggat gcgatacaaa
    16141 gaatcaaatt tgctgaccgg gtttttgtct ttgcccgagg attttcagaa atgattggcc
    16201 aagaaatgct ggtaaaactt caattaacgg gaaaaaattg tcaaatgcat actgatccag
    16261 aaattatcaa aagcatcagt cagaaactga ctaagaaaga cagcgttatt tttgtttctt
    16321 tgaacggcga gacaaaagaa ctcgtcaccg ccgcaaagaa ttgctatgat gcagagattg
    16381 gttcgattct agttacagcc aatcattcct ctacactgaa agactattgc gagatcaatc
    16441 tcgtaggttt caaatcagaa ggttcttatt tccctgatta tgaagtacgg tcacgcttgc
    16501 ctctccagat tatcgcgaga attctgcttg acgcctatgt attgcgtatg ggggagaatt
    16561 gagaagcagt ttattatggt tggttacagt ttaaaacatc acatttttta ttctttatat
    16621 tgtatagact cacgtaaact ttttatgtat aaagttattc acaatctata aagttacttt
    16681 aagtaacaaa aaataattga aaatacttaa aatcaaaaaa tatcttttta atcaataaaa
    16741 aaattgacag ttttattaat aataagctat tctgttatag aagaaaaaat tgtttgttat
    16801 tattagcaac aaaaaaagga gtgcatcatg aaaaagttat ctcaaaaacg tttagctcaa
    16861 atcattattg attctagaaa atctctgaaa atgacacaac aacaacttgc agtagctact
    16921 ggtatcaacc gtgccttaat tagtcgatta gaatctctcg attttatccc gtcaatacaa
    16981 caattagaat cattagcaga agttctaaat tttgaaccaa cagatctatt tataaatgaa
    17041 tcaaataaat caaacagaac aaaacatcag tcgaagaata ttgctgtagc cggtactggt
    17101 tacgtaggtc tttccattgc tactcttctt gcccagcaca atcaggtaac agcagtagac
    17161 attcttcctg aaaaagtaaa acaaattaac aataagaaat ctccaataca agacgattac
    17221 attgaaaaat atctagctga aaaaaatctt aatttaattg caacgactga tggtgcagcc
    17281 gcctatagag aagccgattt tgttgtcatt gctgctccaa caaattatga tagtaaacaa
    17341 aattattttg atacttctgc tgtagagtca gtaatcaaat tggtgttaga agtcaatcca
    17401 aaggcaataa tggtcatcaa gtcgacggta cccgtaggct ataccgaaag tattcgtaaa
    17461 aaatacaata ctaaaaatat tctattcagc ccagaatttc tcagagaatc taaggcatta
    17521 tatgacaatc tatatccttc gcgaattatt gtcggcacgg accaaactga caaaacttta
    17581 cgagaagcct ctcacacttt tgcagattta ctccaagaag gagcaatcaa aaaagatatc
    17641 gaaactcttt tcatgggatt cacagaagct gaagcagtta aattattcgc taatacttac
    17701 cttgcacttc gagtatctta cttcaatgag ctggatactt atgcagaaat gaaaggacta
    17761 aatacacaag aaatcattca cggggtttgc ttagatccaa gaattggcac acattataat
    17821 aatccatctt ttggatatgg aggctattgt ttaccgaaag atacaaaaca acttctcact
    17881 aactataacg atgttcctca gaatatgata agtgcaattg tcgatagtaa tcgtacaaga
    17941 aaagacttta tagcagatcg agtgttagaa cttgctggca cgtatgaggc taacagttcg
    18001 tggaatgcag aaaaagaaaa agaggtagtc ataggtgtat accgtcttac aatgaagagt
    18061 aattcagaca acttccgtca gtcatctatt caaggagtta tgaagcgaat taaagcaaag
    18121 ggggcaacta ttgtaattta tgaaccaaca cttgaaaata acactacatt ttttggttca
    18181 aaagtaataa ataatttaga tgattttaaa aatatcagtc acagtattat tgctaatcgt
    18241 tacgatagta atcttgatga tgtaaaagaa aaagtatata ccagagattt atttcaacga
    18301 gattaaaaaa taacacctca gatttgtagt gtctgaggtg tttctataaa cttttataag
    18361 taaaaaaata caattatact tcataaaaag acttatacca ctgcgcaaat ttacgaagcc
    18421 cgtcacgcaa acttgtactt ggtttaaatt caaaatctcg ttctaacgca ctagtatctg
    18481 cataagtaac tggcacatct cctggttgca ttggaactag ttcggtatga gattcaaagt
    18541 cgtaatcttc tggtagcacc cctgctgcaa ttagctcttg ttgtagaata tctacaaaat
    18601 ctagtaggtt ttccggcgta ttgttaccaa tattataaat atgatatggt gggattggta
    18661 gcccatcttc cccatcaatt ttctctggag cgcactgcat aaccctcttt actccttcaa
    18721 caatatcatc tatataggta aagtcacgct tgcaattccc ataattgaat atttggatat
    18781 tatcaccagc acgaagttta tcagtaaaac caaaataagc catatctgga cgcccagcag
    18841 gaccatatac tgtaaagaaa cgtaaccctg tagacggaat attgtaaagt ttagaatatg
    18901 catgtgccat tgattcatta cttttcttag ttgctgcata caacgatact tgattgtcta
    18961 ctttatcctc tgtagaataa ggaattttct tattagtacc ataaacggaa gacgatgagg
    19021 catacactaa atgttccaca ccagattctc cattatcata tgaatgacga caagcttcaa
    19081 gaatattata gaatcctatt atgttagatt cgatatacat atctggatta gtaattgaat
    19141 aacggactcc tgcctgagct gctaaattca ccacgatact tggtttataa ttatcaaaga
    19201 tgaaatcaat tgttgcttta tcagcaatag aacctttgat aaaattccaa gtagatcctg
    19261 gatggttctt tgcctccgtt tctatctctg ataatctata gttcttaata gagacatcat
    19321 agtaatcatt catattgtca atgccaatga tttttattga tgactgagta cgtaataact
    19381 caagaaccaa atttgatcca ataaaaccgg ctgcgccagt tattaatatt gttctatttg
    19441 ataaggacgt gtttaattcc agcatttttt agcactcact ttcttttttt cttatgaata
    19501 catatttgtt atatattaaa aaatcttatt tagacttatc tattgtcact tttatcattc
    19561 taatctttgc acgtagtaga ataattatac agataggaaa ttgctaagca acccacttct
    19621 ttctattatc tattaactta ttctaaaacg aatagaaatt attcttgatc acataagtaa
    19681 ccttaaaaga aaaa
//
LOCUS       DAXLPY010000051        19155 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.051, whole genome shotgun sequence.
ACCESSION   DAXLPY010000051 DAXLPY010000000
VERSION     DAXLPY010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.051"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            87..2876
                     /locus_tag="ACF3UF_001916"
     CDS             87..2876
                     /locus_tag="ACF3UF_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFD3672017.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            2923..3450
                     /locus_tag="ACF3UF_001917"
     CDS             2923..3450
                     /locus_tag="ACF3UF_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFD3672018.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            3471..4661
                     /locus_tag="ACF3UF_001918"
     CDS             3471..4661
                     /locus_tag="ACF3UF_001918"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD3672019.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            4701..5999
                     /gene="asnS"
                     /locus_tag="ACF3UF_001919"
     CDS             4701..5999
                     /gene="asnS"
                     /locus_tag="ACF3UF_001919"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFD3672020.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            6929..7603
                     /locus_tag="ACF3UF_001920"
     CDS             6929..7603
                     /locus_tag="ACF3UF_001920"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD3672021.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLIAQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            7600..7941
                     /locus_tag="ACF3UF_001921"
     CDS             7600..7941
                     /locus_tag="ACF3UF_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672022.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSFFAQF"
     gene            7971..8330
                     /locus_tag="ACF3UF_001922"
     CDS             7971..8330
                     /locus_tag="ACF3UF_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFD3672023.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGISLIVNIIWLIISGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            8591..8713
                     /locus_tag="ACF3UF_001923"
     CDS             8591..8713
                     /locus_tag="ACF3UF_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672024.1"
                     /translation="MNLDKLPATGFKLSCYPVKIKKASAGWIRAVAMIEKKKKE"
     gene            8855..10936
                     /locus_tag="ACF3UF_001924"
     CDS             8855..10936
                     /locus_tag="ACF3UF_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3672025.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            11247..12713
                     /locus_tag="ACF3UF_001925"
     CDS             11247..12713
                     /locus_tag="ACF3UF_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3672026.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            13328..13867
                     /locus_tag="ACF3UF_001926"
     CDS             13328..13867
                     /locus_tag="ACF3UF_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFD3672027.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            13941..14381
                     /locus_tag="ACF3UF_001927"
     CDS             13941..14381
                     /locus_tag="ACF3UF_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFD3672028.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            14394..14603
                     /gene="copZ"
                     /locus_tag="ACF3UF_001928"
     CDS             14394..14603
                     /gene="copZ"
                     /locus_tag="ACF3UF_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFD3672029.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            14603..16789
                     /locus_tag="ACF3UF_001929"
     CDS             14603..16789
                     /locus_tag="ACF3UF_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3672030.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            16809..18980
                     /gene="copB"
                     /locus_tag="ACF3UF_001930"
     CDS             16809..18980
                     /gene="copB"
                     /locus_tag="ACF3UF_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFD3672031.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6399 a         3343 c         4181 g         5232 t
ORIGIN      
        1 ttctttaaaa agcgatgaga gtatttttct gcactttgta gtataatttc aaaagaacat
       61 tagaggcagg agaagaggaa gatattttga aaccaagaac ttatgcagtc gttgatatcg
      121 aaacgactgg gacgaatcca aaagaagatc ggatcatcca atttggctgc gtcatgattg
      181 aatcaggtcg gatcacttca cgtttttcga tcgatattca tccagggcgg aagatttcaa
      241 aacaaatcca gcatttaaca gggatcacga atcaacgcgt ccaaaaagcg ccttatttcg
      301 aagatgtcgc ccaaacgatt tacaatcttt tggcagacac catatttgtc gcgcataata
      361 tttattttga ttataatttt ttgaaccatg aactcatgcg atgcggactt cctagtttga
      421 agataccagg catcgataca gtagaacttg cacaaatttt cttgccgacg gaaccaagct
      481 ttcgcttagc tgatttgtca gaaagccttg gatttattca tgagaatcct catcaggcag
      541 atagtgatgc cgaagtgaca ggtcaacttc ttttgctgat cgaagaacgg atgagaaaat
      601 tgccaatcat cacgttagag cagattgcgc gattaagtag acacacaggt atggatacga
      661 gtcgtttcat ttatcatgtg attgaagaaa tgaaagaaaa accagagcca cttgatccct
      721 cattagaaat cgtcgatggg ctagctttgc agaaaaaaga agtggaacta ttcacatccg
      781 tccattatgg tgagcggaca tatccaagaa aaaaacaagc aaaagaaaaa atgtttggta
      841 aaacactgat gtatcgaaaa gaacagaaca gactgatgaa tgcggtctac gaccatttca
      901 caaaagatga atcaaaagat ttgatgatcg aagcagctac aggaatgggt aaaacaatcg
      961 gttatctgct gccattgagt tatttggcta cacctgaaaa acccgctgtc atcagtaccg
     1021 tttcgctagt tttgcagcag cagatcatag aaaaagacat tccattgctg aatcaattgc
     1081 tagatcagcc catacaacct gtaattatca aaagctatcg ccactatatt gatttacagc
     1141 gttttaaagg cacacttgtg gaaccgccag aacaaaaaca atatgctttg tatcaaatgg
     1201 cggtcttagt ttggctgacg caaacgaaga ccggtgattt ggatgaatta catttaacaa
     1261 atttgaacca ttcattcttt gcagatatcg cgcacagagg tattggattt ttagcaagaa
     1321 atcagtcatt ttacgaacaa gactttgttc gtttcttgca aaagaaaatc aggcaaagta
     1381 attttttgat tgtcaatcat gcgtttttaa tacaagaaac acagcgaaaa gaaccattgc
     1441 ttccagctag tccatttttg ttgatcgatg aagtacatca tttgccggaa atcgctgaaa
     1501 aagtaaatga caaacgatta agtattaact atttccataa acaaatccag caattagaag
     1561 aaccaaatca gctgtttgac cgaatacaaa gctatttacc gaaagaacat gaagccttac
     1621 gctggttatc gatttatcga gaagaacttt ctgcgctatg cgaagcacag atttgtatgg
     1681 cagaaggatt aatgagttta gtgagcggca agcaacctaa cggacagtat ccagaagaag
     1741 tcatgatgac aaaagagatg ttggatcagc tgccactgga atctgggaca gccattgatc
     1801 acctgcagct tttttatcag gagatccagc agctacagtc acaaatgcgt ctgacttttg
     1861 agattatcca agaaagctgg acaaaccaga tgcggatcga tttagcaagt ttatatagct
     1921 tatttgatca attagacaag cagtacttgc tgatggatca atggctggaa gactggcgag
     1981 atcatttgat ccattggttc gttcctggga acacagcgca gcagatgatt tttcatctcc
     2041 atgattttca agcggctatg ttgccgtcga ctgtttggta tcctcgatat gatcgtattc
     2101 tttatattgg aggaacgctg aagatcggcc ctaatcgaca ctatctctct aagcggcttg
     2161 gcattgaagc agcacctctt aaagtgattg cctctcctta tgattatgag aaacaggcaa
     2221 ggatctatgt gccaaaagag gcacctgccg tccatcaagt cagcaatcaa gcatatatcg
     2281 attatttaga gacagcactt acaggtctga tcgaacaaga agatcggcca atacttgtgt
     2341 tattcacttc tcatgatgtt ttgcagaagg tctatcagaa aatgcatctg tctatgctag
     2401 aaaaaggacg agaaatacta gctcaagggt ttggcggaag ccgggagaag cttttgaaac
     2461 gcttcatttt gtcagaaaaa agcgtattgt ttggcgctga cagcttttgg gaaggtgtag
     2521 atttgcctgg agatgctttg cagatcgttg tagtcacacg tttacccttc gataatccgc
     2581 ttcgcccgat ggtcaaagct aggaacgctt atttagaatc agaggggatc aatccttttt
     2641 accaggaatc cgtacctaaa gcagctttga agttacgcca agcattaggt cgcttgataa
     2701 ggacggagac agatcgtggc gtattgctta ttttggatcg aagactagtc actgcaaaat
     2761 atggtgcacg gatcatccat gcattaccga aaaaagtacc gatcaaagag ctagctatgg
     2821 aggaaatcta tcaggacatc catgaattct taaagaaaaa tgaagaagga agttagagga
     2881 gctgtctttt ttcataatta aaatctgcta taatgaaaag gaatgaagat aaaggagcga
     2941 cgacccttga agaaaaaaca gacaaaggaa aaaacgatta atcgcgtgtt acttggcttg
     3001 atcgtatttt tattagcggt catcgtgatc agctcgattt tttacttgcg ttccagtcgt
     3061 ccggcggtgc aggcgaagaa agaagcagta gaaatcgcaa agaaatatgc aaatcttgag
     3121 gaagccgatc atttttattg gtttactcga aagaagacat acttttcact gacaggtaca
     3181 aatgataaag gaaaagaaat cgccgttatc attcctaaat ctggtgaaaa agtaaaagta
     3241 ttggatcaaa caaagggact gactgaaaac gaagcaaaac agacaattgc tgcggcccat
     3301 cctgaaatcc aaatcgaaaa agctgcttta gggatgtatg atgatcagcc tgtgtgggaa
     3361 gtagtaggaa aagaaacaaa tgggaaactg aattattacc tgattggctt tgaatctgga
     3421 gatgaagtca agacaatcaa gggaatttaa aaggtaaagg aatgaatggg atggagttat
     3481 caaaaagaac aaaacgatta gaaccgtctg tcactttggc agctgcggca aaggccaagg
     3541 cattaaaagc aaaaggcaga gatgtgctga gtttgactgt gggagaaccg gattttgcga
     3601 caccagaaaa catccaagaa gcagcaatcg aagcaatccg caatgggaaa gctagctatt
     3661 atacaccaac agcaggaatc ccagagcttc gacaggcaat cgttgattat ctgaagaaaa
     3721 actatggact tgtctatgaa ccttcacaaa cagtcgtaac agacggagcg aaatttgctt
     3781 tgtataccct tttccaaacg atccttgacc cgcaagatga agtcatcatt cctgtgcctt
     3841 actgggtcag ttacggtgag caagtaaaac tggcagaagg acttcctgtc tttgtgaaag
     3901 gggaagaatc caatagctgg aaagttactg ttgagcagct agaacaagca cgttcagaaa
     3961 aaacaaaagc cgtaatcatc aattctccat cgaatccgac tggaatgatt tatagcaaga
     4021 atgaactgca ggcaatcggt gaatgggcag taaaaaatga tattttgata gttgctgatg
     4081 atatttatgg tcgtttagtt tataatggca atgagtttac tccaattgca acgatttcag
     4141 aagcaatcaa aaatcagacc atcatcatca acggcgtgtc taaaacatat gcgatgacag
     4201 gctggcgcat tggttatgcg gtggggaatt ctgagatcat caatggaatg atcgctgttg
     4261 cttcccagtc aaccagtaat ccgacagcag tcagtcaata tgcagctgtt gaagcattga
     4321 aaggcgagca agatacagtg gaagaaatgc ggaacgcctt tgaagaacgc ctgaatacgt
     4381 tatatccgct tgtggcagaa ctgccgggtg tttctcttga aaagccgcaa ggagcttttt
     4441 atctttttcc taatgtaaaa gaaacgctac gcatgtgtaa atatgaaaat gtcacacaat
     4501 gggtagaaga tcttttagaa gaaacagggg tagcgcttgt gactggcgaa ggctttgggg
     4561 caccagaaaa tgtccgcatg agttatgcta ctgatcgcgc tacgttagaa gaagcggtac
     4621 gcagaatcaa gcaatttatt gagagtaaaa gtcaaaatta atcctgaaga aattcaagga
     4681 atataaaagg agagtcatac gtggaacaaa ttcaaatcat cgattcgaaa aaccatgtgg
     4741 gagaaacagt aacaatcggc gcttgggtcg caaataagcg atcaagcgga aaaatcgcat
     4801 ttttacaatt aagagacgga acagcctttt tccaaggtgt agttgtaaaa agcgaagtgc
     4861 cggaagaagt tttccaaaca gctaaaaatc tacaccaaga aacatccgtg ttagtaactg
     4921 gagaaatccg tgaagacagt cgttcaaaat ttggttatga aatcggaatt acaaatgtgg
     4981 aagtggtaag cgagagccac gattatccga tcacaccaaa agaacacgga acagacttct
     5041 tgatggatca tcgtcattta tggctgcgtt cttcaagaca acatgcgatt atgcagatca
     5101 gaaatgaaat cattcgtgca acgtatgaat tctttaatca acatcatttt gtcaaaatcg
     5161 atccgccgat cttgactggt tctgcaccag aaggcactac ggatctattc gaaacaaatt
     5221 actttgatca aaaagcttat ttatctcaaa gtggccaatt atacatggaa gctgctgcta
     5281 tggctttcgg aaaagtcttt tcattcggtc cgactttccg tgctgaaaaa tcaaaaacac
     5341 gacgtcattt gatcgaattc tggatgatcg aaccagaaat ggctttcact catcaagaag
     5401 aaagtttaga agtacaggaa caatatgtag cattcttagt acaaaatgtt ttagatcatt
     5461 gcgaatacgc attagatgta ctaggacgag acaaagaagt cttaaaaact tatacaaaat
     5521 tgccattccc tcgtattact tacgatgatg caatcgaatt actgaagaaa aatggatttg
     5581 atgacatcga atggggcgaa gactttggtt cacctcatga aacgttcatt gcgaattcat
     5641 tcgaacagcc tgtctttatc ctaaactatc caaaagccat caagccattc tacatgaaac
     5701 cacatccaac aagagaagac gtggtgatct gtgcagatat gatcgcacca gaaggttacg
     5761 gtgaaattat tggcggaagc gaacgggcaa cagactatga tttcttgcta gaacaaatcc
     5821 gtaatcacgg tttggatgaa aaagaatatt catggtatct tgatctacgt aaatacggtt
     5881 ctgttccgca ctctggtttt ggtctaggcc ttgaacgaac agtcacttgg attgctggta
     5941 tcgaccatgt gcgtgaagct attccattcc cacgtttgtt gaaccgaatt tatccataag
     6001 aggttgtgaa atcagtgcct tgacctgagt attagagaaa caaaacggaa aaatagcttc
     6061 tcatatttta ccgttttttt agctaatatc gagggtcagc tgattgaaca ccgtttatat
     6121 caagaggttg tgcgcctgcc gttcagctcc gagtcacaag gagtaatttc aaaaaacagt
     6181 ttttcatgtt tgatgactat tgtgacttgt gaccgaggag ttggccggag agcaccgttt
     6241 attctaaaaa agaactgcga actctcgcag ttcttttttt taaatacggg ataaaggaag
     6301 tttccagcag acaagagaag aaagcaaaag aaattgctat ttgattcaca aggttctata
     6361 acgaaatcgc aatcaatcaa acatttacaa agaaggtaat tcaaatggaa atctaatttg
     6421 atgatgcttc tgctgttgaa ataaagcatc atctagcacc tgaaaacaaa ctaatagtaa
     6481 cattcgaaga tggagtaggt ccgtattttc agcatgcaat aatccatatg taagttcaat
     6541 tcacccttga aatcatcgga ccagataaag ttatgaccaa tctatcccaa gcaatctaga
     6601 agagatatta gtaaagggac atttactaga agtcttagat gagcctataa atatatgttt
     6661 tgatggcgtc atcagtggtc tgattgacgg aagcttgggt atgatcgatc tctctggacc
     6721 aaacaacgaa ggaatcaagg ggaatccggc acgttaagaa aaaaatagca taaaaaacta
     6781 gacacttgat gagcgttcat tcaattgttt gaagggacta ggctgatgtc attttttata
     6841 catatatttt ctctttcgtc ttgatagggc ttatgggata atataaggaa gaaaatcatc
     6901 gttttattca aaaaggagtt tttgacaaat gaaaaaacgt atattattta tcggtgatag
     6961 cattacagac gcaggaagag accgagcaga agcaactgat ctaggtaaag gttatccact
     7021 tttgattgcc ggaaaactaa tcgcccaata tccaacgatg gaatttgaat gcatgaaccg
     7081 tgggatagga ggagacaaaa ttgcagatct gcaagtacgc tggcaagaag attgtttagc
     7141 tttacaacct gactatgtat cgattttgat cggaatcaat gatacctggc ataatactag
     7201 cgatcaggct atattcggaa ctgagaaatc tgctcagcaa tttgaatccg tttatcgaaa
     7261 attactaaat gaacttcaaa cagcggaaat ctgcaacatc atcttgatgg agccgtttgt
     7321 acttcctata accgacgacc gtcatggctg gcgtaaagac ttagacccta aaatccaaat
     7381 tgttcgtaaa cttgctaagg aatatggcgc attgctggtt cctttagatg gtatattcaa
     7441 tgctttaggg attgcttatg gtttttcgaa atatacaaga gaagatgggg tccacccaac
     7501 gattggtgga catgagatca ttgcacaaag ctggatagat gcaattgccg cagtcgattt
     7561 ttttagtgga gataaaaatg agcgaaagaa aagtgaaaaa tgatggaaat aaggtgggca
     7621 gtaaaagaag atttacctca aatcaatcag ctgattactg atcatccaga atcattcgta
     7681 aaagcaaaaa cggcagctga cctaaatgat aagaataaac tattgctcgt tgctgtaaca
     7741 aaagaaaaac ggattatcgg atttgcgcaa gcggacgtgc aacagtcaga agaacgattg
     7801 gatcagcgac catcaggaaa actaatccaa cacacattag taacaaaaga aaatacggaa
     7861 gaaatccaaa aaaaatttgc agaatatttg atgctggaag ctaaaaaaag aagaataaaa
     7921 tcattttttg cccagtttta atcaaaaaca gtaatagaag gagaaatata atgagttgtt
     7981 taggaaatgt catctggttt atattcggcg gactaatcgg tggtcttagc tggttagcag
     8041 cggggatact ttggtgtatc acgatcatag gtatcccaat cggtatgcaa tgttttaaga
     8101 tcgcctccct ttcttttgcg ccttttggca aagaagtaat ttatcaccag tctggcatat
     8161 cattgatcgt taatatcatc tggctgatca tttcaggcct accaattgct ctcgcacatg
     8221 tcgtcagcgg catccttcta tgtatcacga tcatagggat accttttgcc aagcaatctt
     8281 tcaaacttgc tcgattggcg ttgatgccat tcggtgcaga aattgtataa aaagagaata
     8341 ataaaggtta gaaaacgcat agagtcaggt gggatacatg tatttcacct gactctatgt
     8401 gttttcctgt ataagttctc ccatgtgact tttacgtctt ttatttatat gggattactg
     8461 tttatggaaa gttgaaataa ttttcattaa agaactcttg ctatattttt gaaagcttag
     8521 tggagcttcg aatatctggg aaggacattt tgcagggatt gaaaaaagat attgtcctat
     8581 cgaaaaatta atgaatttag acaaattgcc agcaacaggc ttcaaactta gttgctatcc
     8641 tgtcaagatc aagaaggcaa gtgcgggttg gataagagca gtggcaatga tcgaaaagaa
     8701 aaagaaagaa taagccaaaa catctgtatg gaagaaattt tccgatgcag atgtttttca
     8761 ttttttcttt cggatacctt gacatatgaa taaccgttca tttataatta gttatgaaga
     8821 gatattcata tgttgaggcg aggaggtcat taaaatgaaa agttacagat tagaaggttt
     8881 agattgtgcg aactgtgcaa tgaaaatcga aaaaggagtt cagaagatca atggagtcaa
     8941 ggaagcaacg gtaaacttca cttctggaaa actaacgatt gacgcagagg aagatcattt
     9001 ggctacgatt gaacaagaaa taaaaaaagt agtgaaggaa ttagaaccag atgtcaaagt
     9061 aacagaaata gataaggaaa aagtatctga acatggaaat gaaaaagaga gaaatacgct
     9121 gttccggatt ttattttccc ttgcaggtat cgctttattg ctattatttg attttaatga
     9181 accaattcgc ttgatagggt atttattgat ttatctgctg ataggatatg atgtagtgaa
     9241 gaaggcagtg atgaatatcg tcaaaggaaa aatctttgat gagaattttc ttatgtctgt
     9301 tgctacgatt ggcgctatgt tgatcggtga atatccagaa gccgtagcag tgatgctatt
     9361 ttatcaaatc ggcgagtatt tccaaggatt ggcagtcagt cattcaagaa aatcgattcg
     9421 cgaattgatg gcgatccgtc cagaaacagc tcacgtgcag acgacggaag gattgatgac
     9481 cgtgaaccct gaagacgtgc agatcggtca gtttgtactt gtgaagcctg gtgaacgtgt
     9541 accgttagat ggaacgatca tcgaaggaga atcattagtc gatacgtcag cacttacagg
     9601 agaatcagtc cctaaatctg tatatgttgg tgaaacagta ttaagtggat ttatcaataa
     9661 aaataaacca tttttagttc aagtagaaaa atcttatgaa aattctacta tcagcaaatt
     9721 attagaatta gtagaaaatg ccagcagtaa aaaagcacca gctgaaaatt tcattactaa
     9781 attcgcgcgc tattacacac cagtcgttgt aggattggcc gttttattag ctgttttacc
     9841 tccacttgtt gtttctggag cggcgttttc tgaatggatc tatcgagcat tgacattttt
     9901 agtgatctca tgtccatgtg cattagtgat ctccgtaccc cttagtttct ttggcggtat
     9961 cggaggagca agtaaaatcg gtgtattagt aaaaggttca aattacttgg agttgcttgc
    10021 acaaactgag acagtggtat tcgataaaac cggcacatta acgaaaggtg acttttcgat
    10081 ccagacgatc gatacaaaaa tcgatccaaa gatattcatg caatatgttg cgagtgcaga
    10141 acagttttct acacatccga ttgctcaatc tgttttagaa ggctacgcag gtccgctttt
    10201 accaacagct aatatccaag aatttgcagg tgaagggatc ttagctgaag ttgatggcaa
    10261 acaagtatta gcaggtaatc acaaattgat ggaaagattt gaaatctctt ttccttcaag
    10321 tcaagaaatc ggtacattgc tttatctagc gatcgatcaa agttacagtg gttatcttgt
    10381 tattgcagat accttgaaag aagatgccgt agacgcattg gttcaattaa aaaaggctgg
    10441 tgtgaagaac acagtcatgt tgacgggcga ttcgaaaaaa attgctgatc atatcgggaa
    10501 gcaagtaggc gtggacaaga tatatagcga attgcttcca gaagataaag tgcagcggtt
    10561 agaggaaatc ttacaaagaa acaataaaaa gaccgcattt gtcggagatg gaatcaacga
    10621 tgcaccggtg ctagcaagag cagatgtagg aatcgcaatg ggtggattgg gaagcgatgc
    10681 tgcaattgaa gcagcagatg tagtcatcat gaatgatcaa ccatcgaaga ttgcagaagc
    10741 aatccattta gcaaagaaaa cattgaaaat cgtcaaacag aacattgtct ttgctattgg
    10801 gataaaaatt ttggtacttg ccttaggtgc ttttggtttt gcatcaatgg gagatgcagt
    10861 atttgcagat gttggggtga cagtattagc tgttttgaat gccatgcgaa gcttgcatgt
    10921 aaaaaataaa cgttgatcaa tgaagaggac gaatgaacgt cctctttttt ttatatcctt
    10981 ttcttaatga aaaatgtaaa gaaaatagat aggattataa aataactaat gtttttaatt
    11041 ttgcagaaaa ttcaaaatag cttgaaattc aataaggtaa atgaaataaa agaaaataac
    11101 ttattttttt gatggaaaaa atatgaaaaa acgatgtgta ttaaataaaa gaatacacac
    11161 ataaaataac actgtcttgt aagtttgtta aaaattgaat atgattacat ctggataaca
    11221 aatttttatc ataaaggaga gaacgaatga acaacaaaca attacgctgg tttactgttg
    11281 cgttaattgc atttaacatg gtttggggca tggggaatgt agttaataac tatgctcagc
    11341 aaggagtatc agttgtcacc tcttggctat tgattttggc catttatttt attccatacg
    11401 cattgatcgt tggacaatta gggtcagcct tcaaggatag taaaggaggc gtcagttcat
    11461 gggtcgaaaa tacgacatct aataaacgac tggcatacta tgccgcttgg acttactggg
    11521 tcgtccatat tccttatttg gcacaaaagc ctcaagcaat cctgattgct ggcggttggg
    11581 cagtccaagg aaatggaaat atcgtaaata cgatgtcagt acaaatggta gcagttattt
    11641 cacttattat atttcttgcc tttttatatt tatcaacaaa aggactttct actttgaaag
    11701 tgattggcgg actggccgga acagcgatgt tcgtcatgtc gatcttattt attcttttag
    11761 ctgtaacggc accgttcatc aatccaacga tggaatttgc cacaccacat atgaatcaag
    11821 tgaaaacata tattccaaca tttgatttca gttatttcac aaccgtttcg atgctagtat
    11881 ttgcagttgg aggagcggaa aaaatatccc cttatgtcaa ctctacaaga aatcctgcaa
    11941 aggaatttcc taaagggatg atcttcttag cagcaatggt agggatttgt gctgtattag
    12001 gctcagtcgc aatgggtatg ctgtttgcta gcgataatat tcctaaagac ttgatggcaa
    12061 atggggcata cagtgctttt caaattttag gtaattacta tggtatcggt aactcattga
    12121 tgatcattta cgcattgaca aacatgattg gacaaatctc cgcattagcc ttttcaattg
    12181 atgcaccact aaaaatcttg ttagcagatg cggatccaga atttgtacca aactggctac
    12241 gtaaacgtaa tcgtaaaggt acattggtga atggttatct tctgacaggt atactagtag
    12301 gaatcattat tttgttgccg atctttggta tcaaagatat gaatgaatta gtaaaatggt
    12361 tgacgaactt gaactcagtt gtcatgccaa tgcgttacct atgggtgttc ttggcatata
    12421 tgatgttgaa taaagcttat aagaaattca attctgaata taaatttgtt aaaaatccaa
    12481 aaatcggttt tatctttggt gcttggtgct ttgccttcac tgcgtttgca tgtatcctag
    12541 gaatggtgcc aaaagtagat tatactgctg atcctaaagc atggtggttc caattattca
    12601 cgaatatcat cacaccaatt gtcttgatct tattaggtat gatcttgcca gcaattgctc
    12661 gtcgagacaa aaacaaagaa atcactgaac cagaaacagt ggttcagcct taaaatagaa
    12721 atacttgtta caagaggttg tgacagaagt ggtcagcttc aagaaataag aaggaattta
    12781 cgaaaattgc ttctcaaatt tttgtgaagt ttcggcttgt ttttcgcaga agctacttct
    12841 ggaacaccgt gaatcagagg ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc
    12901 aaacaaaaat agcccctcat atttttcgtt ttgctgggct tattaccgca gatgcaagct
    12961 tttgaacacc gtttaagaaa gaggtagtga gcctgccgtt taactccgag tcacaaggag
    13021 caatttcaaa aaacaacttc tcatgtttgt tgactattgt gccttgtgac cgaggtgttg
    13081 gcaggagaac accgtttaag gaagaggttg taaaatcagc gatttgacct gagtattaga
    13141 ggaacaaacg aaaaaatagc tcctcatatt ttgccgtttt ttgagttaat gctgaaggtc
    13201 agctgattga acaccattta ttcgaaacaa gggactttga cacgactttt gtcacagtcc
    13261 cttgtttttt tgcggcgtta taagtggtat gatcgaacca aattccaaag agaagtgagg
    13321 gagaagaatg aagatcatcg tgattggaca aagtgggtcg ggaaaatcga ccctcgcaag
    13381 gaagatcaaa gaaatcaccg actttccgct actgccgcta gaccttttat ggcatacaac
    13441 agactacagt attcaggcaa aaaagtggtt tttgcaagaa cagcaatcgt ttatggtatc
    13501 taatccgtca tggattgttg aaggaaatta tacttctaca ttagaggaaa ggattaaaga
    13561 agcagataag atcatttggc ttaaagtgcc gcgttatctc gccatctacc gagtagtttg
    13621 gcgttctcta aaaagaaaga taaacaaaaa atctcggcca gatatgcctg aatcattttc
    13681 agagaaacta aacagggaat acttagaatt tttatctttt atctggcatt ttgaagaaaa
    13741 caatgaaccg aaaatacagc agctgatcca agtagctaat gcaagaaata aactgatcat
    13801 ccttaaaaca agacgagaga aacaagaatt tttaactaaa ttgaaaatag agagcaaaaa
    13861 taattgacag tttttgttta caagcgtaat ctgtattcat aagctaatga ttacatttgt
    13921 aaacgaaagg tgtgaaataa atggaaaaag tcaaaacgcc agtaaagatc agtgattcag
    13981 agtgggagat catgcgtgtt atttggacac ttggacagac gacagcccaa gaaatcacgc
    14041 agatcttagc tgattcgatg gattggaaac cagcaacgat caaaactttg ctgggacgtt
    14101 tggtaaaaaa agaagtgatc tggacagaac aagaaggaaa aaaattcatt tatcatccag
    14161 ctgtctcgga gatggaaaca gttcgcagtg cgacggaaaa tcttttttcc catatctgtg
    14221 caaaaaggat tggagagacg attgcggatc tagtagaaga agccactttg actcaagaag
    14281 atatcaatga gattttgaaa caactggaac aaaagcaacc agtagatacg atcgaatgta
    14341 actgtatccc aggtcaatgt gaatgtaaac aacatcaata ggaggaagaa aaaatgaaac
    14401 aacaattttc aatcgaaggt atgagctgca atcattgtgc agcaagagta gaagaaacag
    14461 taagcgcact tgacggcgtg caaaaagtga aagtaaattt gaaaaaagca aacggtacgg
    14521 tcaagtttga tgaaacaaaa gttcaatccg aaaagatttg tcaagcaatc aatggattgg
    14581 gttataaagc agaggtgatt tgatggcaac agcagaaacc aaaatggata cgttcgtcat
    14641 tacaggtatg acttgtgcaa attgttctgc taggatcgaa aaagagctga acggacaacc
    14701 tggtgtggtc aatgccacag tcaacttggc cactgaaaaa gcaagtgtca aatatgaagg
    14761 gacgaccact gaaaaattaa tccaaagcgt agaaaacatc ggttatggtg caattttgta
    14821 cgatgaagcc cacaaacaaa aaattgcaga agaaaagcaa gcgtatttga aaaaaatgct
    14881 attcgatctt atattgagta cggttttgac tttgccgttg atgttgtcaa tgattgctat
    14941 gatgttagga agccatgcgg cgattgttca cttttttcat tttccaatcg tccagttagt
    15001 gctgtctgct cctgtccaat tttatgtcgg tgctcgtttt tataaaggtg cgtaccatgc
    15061 aatcaagacg aaagcaccaa atatggatgt attggtagca attggaacat cggctgcctt
    15121 tgcattgagc atttacaacg gatttttccg tggacacccc caagatcttt attttgaaag
    15181 cagcagtatg atcatcacgc tgattttgct cggcaaatat ttggaacata cagcaaaaac
    15241 gaaaacaggt aatgcaatca aacaattgat gtctcttcaa acaaaaaccg cccaagtgat
    15301 aagaaacggg aaagaagaaa cgttagcgat tgaagaagta gtcgttggtg atcaactagt
    15361 catccgtcct ggtgagcaga ttccagcaga tggtcgaatt atttcaggaa gcagtgcgat
    15421 agatgaaagt atgcttactg gtgaaaatct tcctgtagaa aagaatccgg atgacacgct
    15481 ttttggcggg acaatcaata cgaatggtct gctacacatg gaagtcacac aagtcggcaa
    15541 gcagacagta ttagcgcaaa tcattcaaat ggtggaagat gctcaaggga gcaaagcccc
    15601 aatccaaaaa atcgcagatc ggatctcagg gatttttgtt ccgatcgtat tagtcatcgc
    15661 gtttatcacg ctcatagcta caggtttgat cactggtgat tggcaactcg cattgatcca
    15721 tagtgtctct gtattagtca ttgcgtgtcc atgtgcatta ggtttagcga ccccaacagc
    15781 tattatggta ggaacgggtg ttggtgcacg aaatggaatt ttaattaaag gcggagaagc
    15841 attagaagca gctgctcact tagacagcat tgttttggat aaaactggaa cgattacaga
    15901 aggaaagccc aaagttacag atctagtcgg ttcaaaagaa gtcctatcta ttttttatac
    15961 tttagaacaa gcttctgaac atccactagg taaagcaatc gtggaatacg gaaaactgca
    16021 agaagcagca acatacgata tgattgattt tacagcccac ccaggtgctg ggatcagcgg
    16081 tacgattaat ggagtacgct attttgcggg tacacgtaaa cgattaattg aattgaacct
    16141 atcatttgat gaataccaag aacacgcgtt agaattagaa cagcagggaa aaacagtcat
    16201 gtttttagct gatgaaaagc aagtgatcgg gtggattgcc gtggctgatc aaatcaaact
    16261 agaagccaaa caagcaatca agcagctcca gaataaagga ttagatgttt ttatgctgac
    16321 aggagacaac aaactggcag ccgaaacgat tggtaaacaa gttggtattg atccaaagca
    16381 tatctttgct gaagtacttc cagaggataa agcagcctac gtagaaaaac ttcagaaaga
    16441 tggcaaaaaa gtcggtatgg caggcgatgg aatcaatgat gcaccggcct tagcattagc
    16501 tgatgtcggt atggcaatgg gaagtggaac ggacattgcg atggaaacag ccgatgtgac
    16561 gctgatgaat agcagtttgg catccattgc acaaacaatc gagttgtcta ggttgacatt
    16621 gagaaaaatc aaacaaaatc ttttctgggc ttttgtctat aatacgattg gtattccttt
    16681 tgccgcacta ggctttttga atccaatcat tgcaggagga gcgatggcgt ttagttccgt
    16741 cagtgtattg ttgaactccc tgagcttaaa tcgacacatg aaaaagtaag agaagggatg
    16801 gagtaaaaat gaatgggaac gatatggaga aaaaacatga gcataaaaaa gaagtagtaa
    16861 acaaagaaag tacagaatct catgaaaaac agatggagat gaaacatgac catagtcaga
    16921 tggatcattc catgcacatg ggacataacc atggagatat agcaaacagc aaacaaatgg
    16981 accattcgat gcacatggat cacgaacacg gcggcatgga tcattccatg cacatgggga
    17041 atttcaaaca aaaattttgg ctatcgctta tcctagctat cccaatcatt cttttttcac
    17101 caatgatggg aatggaattt ccatttcaag taacgtttcc tggttctgat tggctcgtat
    17161 tgatcttagc aactatacta tttatctatg gcggtcagcc atttttaagt ggagctaaga
    17221 tggaattgaa acaaaaaagt cctgctatga tgacactgat cgcgatgggg attacagttg
    17281 catatattta tagtgtctat tcgtttatcg caaatctgct caatccacat acacacgtca
    17341 tggatttctt ctgggaattg gctactttga tcgttattat gctactaggt cactggattg
    17401 aaatgaatgc tgtgtcgaat gccagcaatg ctttacaaaa actagcagaa ttactgccag
    17461 aatcagtgaa acgcttgacg aaagatggaa aagaagagac agtttcattg aaagaagtaa
    17521 acgaaggtga tcgtttgatc gtccggtctg gtgataaaat gccaacagat ggtgtaatct
    17581 tgaaaggtga aacaattgtt gacgaatcag ctgtgactgg cgaatcaaga ggaatcaaaa
    17641 aacaagccaa tgacaaagtg attggcggtt ctatcaatgg ggatggaacg atcgaaatcg
    17701 aagtaactgg aactggtgaa aatggttatc tagcgaaggt tatggaaatg gtgcgaaaag
    17761 cacaaggaga aaaatccaag ctagagtcat tatctgacaa agtggcaaaa tggctgtttt
    17821 atgtcgcatt aattgtgggt atcctggcat tcatcgcctg gttgttcttg acagatcttc
    17881 ctaatgcatt agaacgtatg gtaacagtct ttatcatcgc ctgtcctcat gctctaggtt
    17941 tagctatccc attagttgtt gctcgctcca catcaatagc agctaaaaac ggattacttt
    18001 tgaaaaaccg caatgcactg gagcaagcca atgatctaga tgtgatcatg ctggacaaaa
    18061 caggaacact aacagaagga aaatttactg taacgggtgt cgaagtactt gatgatgcgt
    18121 tcaataaaaa tgaaatcctt caatatctag gagccttgga agcgaatgcc aatcatccat
    18181 tggctgttgg cattatgaat tatttgaaag aacatgaaat caagccttat caagctgaaa
    18241 atctaaaaaa tctttcagga gtcgggctag aggcaacagt caaaaaacaa caagtgaaaa
    18301 tagttaatga aaaagaagtt gagcgtctcg gattaaacgt agaacaagca ttattgaaac
    18361 cttaccaaga acaaggaaat accatcagct tcctgatttt agaaaatcat ctagctgcaa
    18421 tcgttgcttt aggtgacgta gtaaaaacag aagcaaaaga atttatccga acattgaaag
    18481 aaagaaaaat cactcctgtc atgcttactg gtgacaataa aaacgctgcc caagcagtag
    18541 cagattattt agggatcgaa gaatattatg gcggtttatt accagatgat aaagaagctg
    18601 ttgtccagaa ataccttgac caagggaaaa aagtaatcat ggtgggtgat gggatcaatg
    18661 atgcgccaag tttagcccgt gcttcaatcg ggatggcaat cggtgcaggg acagatatcg
    18721 caatcgattc tgcggatgtc gtattgacaa acagcgatcc aaaagatatt ttgcattttc
    18781 ttgatctagc caagcaaacg cgaaagaaaa tgatccagaa cctctggtgg ggggcaggtt
    18841 acaatattct tgcaattccg ctagcagccg gaattcttgc gccaattggt atcatattaa
    18901 gtccagcagt tggtgctgtc ttgatgtcgt taagtacggt agttgtagct ctaaatgctt
    18961 tgacattgaa aatcaaataa taatgaaaaa aggggctctt tgtcaataag gactgatggg
    19021 ttgtacaaaa tcaaatctgg gtcagaatga acctcattct ggctcagatt ttttgttatc
    19081 ttactttgat taattgattg atcaaaaaga ttctaattct catgttctca aatgatttaa
    19141 atccgtagga tactc
//
LOCUS       DAXLPY010000052        17766 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.052, whole genome shotgun sequence.
ACCESSION   DAXLPY010000052 DAXLPY010000000
VERSION     DAXLPY010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.052"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(45..755)
                     /locus_tag="ACF3UF_001931"
     CDS             complement(45..755)
                     /locus_tag="ACF3UF_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFD3672032.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(773..1269)
                     /locus_tag="ACF3UF_001932"
                     /pseudo
     CDS             complement(773..1269)
                     /locus_tag="ACF3UF_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(1306..1758)
                     /locus_tag="ACF3UF_001933"
     CDS             complement(1306..1758)
                     /locus_tag="ACF3UF_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3672033.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWSFVKKGNKRIY"
     gene            complement(1893..2498)
                     /locus_tag="ACF3UF_001934"
     CDS             complement(1893..2498)
                     /locus_tag="ACF3UF_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFD3672034.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(2948..3568)
                     /locus_tag="ACF3UF_001935"
     CDS             complement(2948..3568)
                     /locus_tag="ACF3UF_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3672035.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(3570..4439)
                     /locus_tag="ACF3UF_001936"
     CDS             complement(3570..4439)
                     /locus_tag="ACF3UF_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFD3672036.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(4462..4869)
                     /locus_tag="ACF3UF_001937"
     CDS             complement(4462..4869)
                     /locus_tag="ACF3UF_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFD3672037.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(4888..6177)
                     /locus_tag="ACF3UF_001938"
     CDS             complement(4888..6177)
                     /locus_tag="ACF3UF_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3672038.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINDQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(6204..6506)
                     /locus_tag="ACF3UF_001939"
     CDS             complement(6204..6506)
                     /locus_tag="ACF3UF_001939"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3672039.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(6531..8624)
                     /locus_tag="ACF3UF_001940"
     CDS             complement(6531..8624)
                     /locus_tag="ACF3UF_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3672040.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(9113..9841)
                     /locus_tag="ACF3UF_001941"
     CDS             complement(9113..9841)
                     /locus_tag="ACF3UF_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFD3672041.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(9986..10699)
                     /locus_tag="ACF3UF_001942"
                     /pseudo
     CDS             complement(9986..10699)
                     /locus_tag="ACF3UF_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
     gene            complement(10700..12607)
                     /locus_tag="ACF3UF_001943"
                     /pseudo
     CDS             complement(10700..12607)
                     /locus_tag="ACF3UF_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
     gene            complement(12721..14053)
                     /locus_tag="ACF3UF_001944"
                     /pseudo
     CDS             complement(12721..14053)
                     /locus_tag="ACF3UF_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(14019..15497)
                     /locus_tag="ACF3UF_001945"
     CDS             complement(14019..15497)
                     /locus_tag="ACF3UF_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3672042.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(15802..17637)
                     /gene="tdc"
                     /locus_tag="ACF3UF_001946"
     CDS             complement(15802..17637)
                     /gene="tdc"
                     /locus_tag="ACF3UF_001946"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFD3672043.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEQVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
BASE COUNT         5054 a         3810 c         3016 g         5886 t
ORIGIN      
        1 aaaaaaaaac ggcaatgaat gccgctcttc ttatttcgat tcttttataa ttctgcttct
       61 gattcatctt tggttagtgt gtgtctaaca ctagttacgc caaatgtttg atcgattttt
      121 tccttcaacg cttcgattgc ctgtgcgcca cgtgccgctt gttcagcatt gatggattca
      181 atgaccagca ccgctgcttg tgtttcttcc gtcagcatcg ttctttgggc ttcacgccag
      241 ttgagacagc gacagatcgc tccttgttca tcatagtaga tgatttcttc cggaagtgcc
      301 ggagcatcgg aatctgcacc taaaggcagg aatgattcgt caccttgggc ttttcctaaa
      361 tgcagatttc ctgcgatctt ttcgatatct tctccgccgc aaggtacgcc aaaagacaag
      421 gaaatactat tatagatatc tacaagcgga ttgattggga aaaattcccg ttcttgattt
      481 gcacgtttca gtaaagcttc aatagaagaa cgtgcacctt ttttagtctt gaatgtggta
      541 aatgcctgac gccactgagc aatgacttcg ttttggctga atgtttcttc tgtaaggtaa
      601 tttcttgctt cttttgctgc ctcattcaat aattgatgat acgtttcttc actttctttt
      661 gttacgtggt tatcgatacc atttacggat aagatttcga tggttgcttc aggaaatact
      721 tcccagaaat tggtatccac tattactttt ttcatctgtt cacacctctt gattagaata
      781 attgcttgat gaatagatag tctgtttggg gatcatctcc catataaaaa acatgttcgc
      841 tgtatttgat aaatcctttt ttacgataaa aagcgagcgc aacatcgttg tgttcccaaa
      901 caccgagcca aatggctgtt ttttgctttt cttttgcttt ttcaatagct gtatctagta
      961 aaaatgtacc gataccttga tgtttaaatt tttttcgtac atagattcgc tcgatttcta
     1021 aaaaatgatc agccatttcc tcagattgac tcgttcctgt atttagtttc aggtaacccg
     1081 caggctcttg atcgatactc actaggaaaa aatctgtttc tttatctttt agctcttctg
     1141 taagtttttc tagtgcataa gcttgtgtca agtaatcagc taaatgctcc ggtaattatc
     1201 ttttccaaat gtatctgtaa atgtttcgat actaatttgt tgtagtaagt ctacatctga
     1261 aggcgtcatt tttcgaattt cgtatttatt cacggcttct tcctttcaat agatcctttt
     1321 attgcctttt ttgacaaaac tccaatcttc gctaacattc ttgcatactt tatttaaaag
     1381 atattccaat tgttttgctt cttcgtcaga aagaccattt aatgcgactg cattggagta
     1441 gttgttttct cgaatgatga aaggatagat ttctgctcct tttttagtcg gatagagttt
     1501 cttgattttt ttattttctt tatcttccaa acgttcgatc atcccattgg attctaattt
     1561 cttgattgct cgggcagtcg ttgtacgatc tactttgatc atttctgcta gtttttcttg
     1621 gatgattcca ggattttcgc aaatacgtac taaataaaga tactgtcctc ttgttaaatc
     1681 gacttctttg aattcgatat tgctaataga gtctagcgct cgggcaatca ttccgatgtc
     1741 tcgaaggatt tcagccattt catcccacct ttattttgtt tgtaagacta gtttacctct
     1801 ttttgttgca aatgcaacta tttttaataa aaaaatcaag ttctttttta ataactagta
     1861 aagtatattc ttttcttctt ttacgaaaaa gctcaatcac aatagatctg gtttttgttt
     1921 tctaaaataa gtaactgttt cttcgttgtt cgcttttctg atagctttgg caactcttct
     1981 atactaaaaa atcccatgtt ggaagtttca ttattctcaa taaacttggc ctcttcaccg
     2041 tggatcgcac aagcaaaaac aagtttataa tactgaaaaa gctgtggaat atctttttgt
     2101 ttattcgtat caaaaactgc tcgcaactga gtagtttcta ctgttaatcc tgtttcttca
     2161 tagacttctt tacgcacatt ttcttcagga gacaatccta tttcagcaaa tccaccagga
     2221 agtgaccatt ctttcgtccg tttatcttcg attagtagga ccttgccatc ttttttgata
     2281 taggcacgaa catctacttt tggtgttgga tgtccttctc caatcgttgt gagcgctttt
     2341 atttcttcga aagtttcttt tcctatttca ctgatcagtt ccaatgaaat cgtccggatc
     2401 tcctcaaaac gctctttatc aaatacatct tttccataat atagaccagc ttgagaaagt
     2461 gcgagtagtc ttttgtattg agccaacttc ttgttcattc tcttcccttc ttttttagca
     2521 aatgtatgac tatgtaatca agtatagaag actggtttaa ttacggcaaa taaatataat
     2581 gaaatctgca ataaataaaa gaatgttaaa aaactcgaga acaaaagaca ttcgacttct
     2641 ctggggctgt gaataaatgg cgttcaaaag cttgcatctg cggtaataag ccccatcaaa
     2701 cgaaaaatat gacgagctat tcttgtctgg ctgttcttat taattgaggc aggacagctt
     2761 tttcacaacc tccccactaa acggtgttct cctaccaact cctcggtcac aagtcacaat
     2821 attcatcaaa catgagaagc tgtttctttg aaattgctcc ttgtgactcg gagctgaacg
     2881 acaggctcac gacctctcgg taaacggtgt tcaaaagcca atttttcgat attaagccat
     2941 ttctttgtta cttattgtca ttgatttctt tttctaattt atccaatagt ggagtgtaat
     3001 ccacttgagt atagtctgtt acatcaaatt catatagtgt tcctaactgg aatttgtcat
     3061 attttcggtc ggcgatgatc tttttgaatg cttctttcgt aatatgattg gtccctttcg
     3121 ttcgatcttc caatacgtca ccatagtgat aatgatccat gatatagctc aaatgacgat
     3181 ctgattcacg atcacgtttg taccgacgtt gccataacac ttcaaagtct gctgttaggc
     3241 gaatcgtgat cacctgatat ccgtatctat ctgctaattc ttggagtcgt gctttttgct
     3301 tatcactaaa aggatactcg gacacaatca ctttctttcc tgcttccata tacaaatcaa
     3361 gtgctttgta atagaaagga taaactttcg tcctttcttg ttccgcccgt tcttccaaat
     3421 tgttaaaccc gatggattct gcatagtatt ccttgatttc atcgagcgtg atggcataca
     3481 tatctggaaa tcgttcccgt agtttattca taagatatgt ttttcctgta ccaggactac
     3541 cagccagaag aatgaaatac tttttcatct catttatttc ctaagttaat tggactttcc
     3601 aagttcataa acagtccaat cttatgcttg acaatttctt ttactgcttt atttgctgga
     3661 atcacattat ggcgaagaga cttgttgatt tctgtttcac taaaggtttc tttagctact
     3721 ttcgtccagt tgactaaaag ctccgttcca acattgaatt tgcggatccc gttattgatc
     3781 aattcaggat aatcttcttc tttcacacct gttcctccat ggataactag ggggacatca
     3841 actactgcat cgatttcttt cagcaaggga atgtttactt ctgtttttga tttgaattgt
     3901 ccatgattcg taccgatagc aatagctaat gcatccacgc ctgtagcttc tacaaatttc
     3961 actgcgtctt ccggtcttgt atataccttg tcattttcag cgacatggat tccttcttct
     4021 gtaccgccga ttgttccaag ttctccttct acggaaacac cgtgcgcatg ggcatattct
     4081 actactgctt ttgtcttcaa gatattttct ttgaaaggta gatgggaccc gtcatacatg
     4141 acagaagtat atccgctatc gattgcttct ttgatatcat caaagtctcg ggcgtggtct
     4201 aagtgtaaga ctgcatcaac catttcttct tctgcaatag ctgtcattac attgactaac
     4261 acatgcatgc cgatatattt agcggtatcg acacttgttt gaataatgat tggcgaaccc
     4321 atttcttttg ctgcgcctag catggcagga agcatttcta ggttatgcgt attaaaagct
     4381 ccaactgtaa aattcaactc ttctgctgtt tttgttactt ctttcaatgt tgtatacatc
     4441 ttttattgcc accttatctt tttatttgtt tcctttgatc gttacttgtt ttgcaatttg
     4501 tcgcatctca tccattttgc ccatgtagta atcgatccct tgatcatcac cagcacgagc
     4561 agcatctgca cgcttctggt tatagaggct catcagtttt ttatacccat ctccgatcgt
     4621 ctgtttattt tccaagctct tttctaaata ttggatggct tgatcgttct catgcaattc
     4681 agaaaattta agtccaactt gttcataaag ttccgctaat ttatgcctat cttgggtagt
     4741 ggaaatctct tgtttcaatt gtgtaatctc tgattgaatc ttttcggtcg cttctggcga
     4801 tagggctttt tcttcttttg ccagaacttt tttcggttct ttttcttttt tcttaaaaaa
     4861 tccaaacatc attttcccta ctttcaatta aaacgctttc aaaactgggc ttaagatcca
     4921 ggcatataag agtgctgcgg ctactgtatc tacatcggtt gctgtagcat tgatgaatcc
     4981 catcgaatta aagatcgtta ctagcaaagc gggcaataat gtaataaaga aaccatgagc
     5041 aataccgcca atgatcgctc ctcggcgtcc gccaactgcg ttgccaaata tccctgctgt
     5101 ccctccggca aagaaattgg ttagcatacc aggtaaaatc atcgctaagc cgaacatggg
     5161 caaagtaaac atggcaataa tcgtaccaat cgttgtcgta atgaaaccta aaatgacggc
     5221 atttgggcta taaggaaaga aaactggaca atctaaggca gggatcgcat caggaactaa
     5281 tttcatagct atccctcgaa atgccggcac gatttcacct aacagtagac gtacaccagc
     5341 tagcaatata tacacaccca ctacgaattg gatggcttgt aaaaaggcaa acatgatata
     5401 gttttgatct cctgataatt cagaagcgaa tggttcgcct gcaaataaaa cagtgatgat
     5461 atatagcggg accatcacga ccatgacaga caaataagta tcttgcagaa attcgaaatg
     5521 tgtcggcaac ttgatatctt cgatcgactt tttattttcg cctttctcac caaaaagctt
     5581 agcaacaccg gcttcaaata agtacccgat cgtacaaaaa tgacctaaag caatatcatt
     5641 tgatccagtg attttacgaa tgatcggttg cgctactgcc ggcatagcaa tggcgaaaca
     5701 agctccgata aaaccaccga ccaagatcaa tacgatccct cgcagaccgg caaaatagcc
     5761 aaagactgtc gtcatcgttg ccatccataa aattgcttga ccagttaaaa aaatgtactt
     5821 ccattttgtg aaacgagcca aaataatatt gaatacaaaa atggctaaga acgtcagtgc
     5881 aatatctcta cctaaaccca aatcattcat tgcttgatca ttgatagatt caatagaagg
     5941 gatgatccct tgcatatgaa atccttcagt aaagattttc ccgaaataag ttaaacttcc
     6001 aacgatgatg ctcgaaccgg cactcaatac ttgaaatcct aggagtgttt ttaacgtgcc
     6061 agagatgact tgtcctgctg atttcttctg cagtagtaga cccaacatag caatcaatgc
     6121 aatggtgatc gatgcctgag tcaaaatatt ttcgatgata aaattgataa cgctcatgtt
     6181 tttaccctct tttctttttg tatttagata actcccttat cttgcagaac tggggtgatt
     6241 ttttcttcaa tttcattttt tgaaacaata tttttcaaat agatcatcgc cgttttagga
     6301 tcaactgcga acttttcgaa ctgcgaacga aaattttctg ctgtgatgat cacatctggt
     6361 ttcatggaaa ctgcggaaga aatatcacaa tggtccagtt tggcttctac tcctaatttg
     6421 ttcaaaacat cctcagcaga catctgtgct gcaaaactac ttcctaaacc tgcgccgcat
     6481 acgaataaaa tgttcaattt gttcatcttt gttctccccc gtatcattta ttatttctca
     6541 actactgaaa aaagcagttg tttgaaatct tcgatatttg tgcattcaat caatcgatcc
     6601 aacttctctt cgttgttgat caattcaatt agttctttca tgatgttcag atgggagtag
     6661 gagtctactg ctgccaaaca aaaaataatc tttactggat ccatttcagg attaccgaaa
     6721 tcgattggtt gctcaatcgt agctacgctg actcctaatt tattgacccc atcttctggt
     6781 cgggcatggg ctagtgccat gtgtttgcca atcacgatat acggtccgta atcattcact
     6841 gcacgaatca tcgcttcgac atagcgctct tcgacaatgt tttctttaac caatggtcta
     6901 gcagctagtt caatcgattc ctcccaagta gtggcttttt ctttgatcat gatattgctg
     6961 tccgtcaaaa tatcttttaa cataggctgg atctcccttt tgttgatttc taaattgttt
     7021 gtttcgaata atttttctaa cttgccatag atgattcgat ctactcggcc accactttct
     7081 ttcatgacat ctattatttg agtgaataac tccgtcgatt catgactgtt aggctctaac
     7141 cgctgtagtt cttcatttct tttcaaaaag tcttctataa ccaagatatt cgtctcagtt
     7201 aaaatcggat cgacaactaa aagcggctta tttcgataat tcaattgaaa ggtgctgaaa
     7261 accagattga catccaattt atctactaat tcgatttctt ttgaacttaa aactgcagta
     7321 atctcgatct gaggaaactt ttctttcaga ttctctgcta acagatttcc agtagccatc
     7381 ccatggttac agacaacgac tgatttataa acataattca agtctcgctt gattacactg
     7441 gcgatcgtcg aaaagtggat gacaagaaaa gctatctcgt cctccagtat cttgccacca
     7501 attacttctt cgatcgtagg aacaaaatga gtgactgcgc ggtagattgg gaaataattt
     7561 gttcggatgt tttctttcaa tggattcatg acttggatat gattcttgat tcttacaatc
     7621 agtgcagcca tgtgcttata gagattttcg aataaggctt cttcctttag atggaaaggt
     7681 acgtgtgtct cgttctctac aaattggatc aattggatcg ttagtaattg agcttgtacc
     7741 cactcgattg aattggagat atctctagca ttgaacgtct caatagtgaa acgaagataa
     7801 tttctttcta cttgcgggac attgtccaat tgaaattcct cgatcatgtg gtcaataaat
     7861 gcagaaaagc tactgtcttt tatttctgta tttttccaat taatggcaga gataaattca
     7921 tgtttcctga ttcgctggat ccagatcaat gtaaaaagca ggatttgttt tttataaata
     7981 tcatcttctt gtttcaacaa cttattggaa tagatctcct gtattttttt gatttcctcc
     8041 aaaggaaaat aatggagaaa gattttttga gccggtgtta attgtgcatc ttgattcata
     8101 aagaagtcgg tcattcccag attctgattg ataaaatcat agatcatcgt acggatagat
     8161 cgttctgaac ctttataaac cagtccttgc tttccataac tgacgatctc tatcccataa
     8221 ctgaccagtg ttgctcgtaa ccgtctcata tcttcatcta atgtactttt agagatttga
     8281 aattcttctt cttttttgtt tagatggatc gggattcggc tgtaagcaac ggctaaaact
     8341 agatcaaaaa tacgttcgcg ccgattcaaa aagccgtctt tcacatcttt tatttcagtt
     8401 tctaatcgag cttgcttttc cttttccagc ttcaacaaaa aacctttgtt gcgaattgta
     8461 cggatctccg gaagcttttt actgctcaac cagatattcg cttcaagaac ttcctgacga
     8521 atcgtccgct gactgacatt gaactcactt gctagatgtt ttgcttttac tggatattgg
     8581 gctgtcatga ttctgtgaag tatttcaatt gttcttgttt tcatagaaat gatctccttc
     8641 tgatttcaag tatatggttc cgcttacata ataaaaagta gatatttctg ccacttgaag
     8701 tggaaagaaa gtaagcaaag caaacaaaaa ataagccata tgctttttca tctcctcaac
     8761 gaaaaagaca tacgcctatt attacaaaaa ttttgcccat ctatacaaaa aagaggttgt
     8821 gaaaaagctg tcctgcatca agtaataaga acaactaaac taaaatagtg cttcctattt
     8881 tttgtttggt tgttcttatt atcgcagatg caagctttta aacaccattt agtggagaag
     8941 ctgtgacaga gatgttcagc cttgagcgat aagaagcgat tttgaaaaat cgcttcccat
     9001 attttacaaa atcgtgcctt attgccgata ggctatctct ggaacaccgt ttattcagaa
     9061 aaaggagctg cgacaaggct tttgtcacaa ctccgttcat aaatatttcc tgtcaatcca
     9121 gcataatcgg ttgaataaaa tcggcttgcc atcttttttc tttctcagaa aaatcaaaat
     9181 accatatctg agaaaaatac tgtcgttgtg tcttacttcc tgagatcaat cgcccatctt
     9241 ttcgatcgac tgaataatca cagcatctga aatcaattcg gatggcaaaa ctattttcgt
     9301 ggatctgtcg ataatttcct acttcctgaa tagttatttt tttagtatga tttcttacac
     9361 cgtctgcttt gtttttttgc agaactttct gatgttcggc aaacagcttg tctgtataac
     9421 agcttctggc tttttcagga gtttcttctt cccaagcgga ttggatcttc atgaatatct
     9481 tttggatttc caaaaactgt gctttctttt ctttagccgt tcctgacatg cgggacaata
     9541 tctccgattt cagccttttc ttttgtcttt tattcttgac gatagaaaaa gcagaaaccc
     9601 ctcctactga caaaacagct aatgcaagaa accccgtttg ctcataacta gaaggacctg
     9661 tacttggacc ataataccca taagaatctc tgccgtaaga acgactgcca aaataactgc
     9721 ccccatatga acgaccgcca aatgaacctc tgcccgaact tcgaccgcta gatgtacctc
     9781 caccatgacc acccgcgaca gcgaatcctt gggtcggcag agcaaacaaa cataggccca
     9841 ctaacaaaat gattgctaaa taattgattt tttcattgtc ttcctcgtta tcttttatta
     9901 caaaaaacta ttttatcata gccttgctaa aaggaagagt caataaccag atgcataaac
     9961 tgttttttta gcaattttgt cttatttagt cattgagtaa catcggacag atgtatgtgt
    10021 cggcagtcca taattcctct atcttcagca tgaacaagct tgcagacaag agatctgcgc
    10081 ttcctccagg agagatttgg ttttcctgac aaaagtgcaa cagtgctgta aatggacgat
    10141 ttggtaaagc actttgacta gcagcatgag caagtttttg catttccact aacgttttct
    10201 gatcactgcg atgcaatacg catgtgtcat ctagcgaact catcaaaact aacaacatat
    10261 gcatttgttt ctgtacatat gaatcattat ctagctcctt agctgcttgg attgcaagcc
    10321 tgatatgcgg ataccctaat atcgcttctt catatgcacc atttacgcca tatttttgct
    10381 tcaccctatg accatgagtg gtttttttat gacgatattt tgtatcagga aaagcagcaa
    10441 gcttgctgac atcatcaagt attttcgata aagaaaaagg ctgttccata ctgatttttt
    10501 gtgcaatgac actgatcaat agccccattg cccaaatcgc tcctttatgg gtattgatgc
    10561 catttgtagc aatcagcatt gccttttccg cttttcgccc aatctcagca attctttctc
    10621 ttaactcctg atcaatagca taatgccatg ctatttgagc catttcttca aaaaaaggag
    10681 ttagcgtctt agcagactta tccaaaatgc gccgaccttc ttttacggct tttgcgatcg
    10741 tatggaaatt atcatctcct aaaaccatat cagctgcctg tttgcttact tcactacctt
    10801 tgattcccat agcgattcct atatcggctc ttttcaaagc aggtgcatca tttacgccgt
    10861 ctccggtcat tccgacgatt tctccatttt tctgcaaagc tttcacgatt cgcagtttgt
    10921 gttctggtgt cgttcgagca aagacgtcga cttttggtac ttgtcgaatc aactcttctt
    10981 cagacataag atccaaatcg atcccttcta aaactttagc agtatgtttt aagccaattt
    11041 gttccgcgat cgcttttgct gtatctttgt gatcccccgt aatcattttc actgagattc
    11101 ctgcttgttg gcattccttt acagctttga ctgcactttc ttttggcgga tcaatcaacc
    11161 cagcaatccc tgcaaaagtt aattgggtta aagactcatg cgtgagttcc tgtttcgaat
    11221 ctactttttt gtaagcaaat cctaaaacac gctgaccttt tttcgcaaac gctgtggctg
    11281 tttgacccca tgcttcttat tctgaagaag aaagagttga tttagccaat aatacttctg
    11341 gcgcaccttt gacgtaaatc acccctcctt tttcctccgc atgcatcgtt gccatatatt
    11401 tgtattcaga gctgaacgga atttttgctt ctattttttt caaaggcaga tcggctgttt
    11461 cggtgtggcg aatcagtgca agttctgtcg gattgccact taaattttct gttttctgtt
    11521 cttctttcgt ctttaattcc tgacaatttt tcataataaa cagtacgcga gtttcttcct
    11581 ttgctgctac atccacaact gtcatttcat tttttgtcaa tgtccctgtc ttatctgaac
    11641 agatcactgt catagaacct aatgtttcta cagaaggcag tcctttgatg atcgcctttt
    11701 cttttgccat ttcatgtact ccgacagata ggatcatggt caacacagct ggcaatcctt
    11761 cgggtaccat tgacaccacc aaagcgatca tagctgaaag aaggatatgc caatccatgc
    11821 catagcggaa tgttgtaaaa acaactaaga acaagatcaa acaaagaatg ccttgaaaaa
    11881 tttgtttgtt caatcggttg atcttcttga tcagaggcgt cgtttgttgt tcgaccgatt
    11941 gcagtgcttg attgatttta ccgatttctg tcgtgtttcc tgtttctaca acgacaccga
    12001 ctgcagaacc agattgtaca agcgttcctg aaaaagccat atttttttgg tcaccgattg
    12061 attcttctgc tgccaaaacg gaatgatttt tttcagatgc ttctgattct cccgtcaaaa
    12121 tcgattcttc tactagtaga tcatgtactt cgatcaaccg aacatctgct ggaacgacgt
    12181 ctccggcacg taagacaatg acatctcctt ttactagttc tttcgcaggg attttttctt
    12241 gcatcccgtt cgatagtact atcgcttctt gtcccatcag ctgcttcaaa ccattcaacg
    12301 attcttctgc ttttctttct tgccaataac taacgagtcc gttgacgatc actacgaata
    12361 aaataatact tccttcgatg tattcgctcg aagcaaattt caaaaaagag gcaatgatca
    12421 acacgatcat cagcagatca gtaaagtgtt ttgctatttt tttccatcgt tttgtctgct
    12481 gtcttgcttc tatctcatta tatccttgat cagtcaggcg tttctgccgt tcttcttgcg
    12541 acaagccttc tgttgatgtt tgatagtttt tcaatacatc ttctaccgtc aatctgtacc
    12601 agttcatcct atcccctcct gtttaattga tactgttatt atacgcaggg aagttttttc
    12661 aggcgtatcg attatttcag gggggtctga aataattcgt tttgcagaat gtatctgggc
    12721 ctaactgata tttctattgc ttattctttt atatacaaaa tttaagaata caaaccagat
    12781 aaccaataaa aaaggaataa agcgtgtcgt gctttcgaat aacaagctga aagcaattga
    12841 agtaaaaaac accaacaaag caagatcttt atatctttgt gtagtgttcc gtttcttttc
    12901 tttaataaat tgaacatgtg cacacaagat cgaagaccac acaaatagaa aacaactcgt
    12961 tgtcatgcct gccaaaagct gaaaaaacaa tcgactatca gctacaaaaa aaatgtagac
    13021 aaagaccgac aaaaaataac atccctgtaa ttaaaatacc gtgtaaaggt acgcctttct
    13081 tagaaagcgc acaaaaccaa tggggcaaac ttttctcttt tgctgtttga tataaaatcc
    13141 tgctagtact gtagactgca ctatttgctg aggacaaaga agcaaccaaa atcattagat
    13201 tgacaattgc tgctccgctt tggcaatgga tcacttgcag catagtcact aaaggacttt
    13261 cttttaaatc taaacaatgc catggaacaa caaataaaat cgacaaaatc gttcctatat
    13321 agaaaaagag gatacgccaa ggcagacagt tgattgcatt tttcaaattc ttttgtgggt
    13381 cactcgtctc accaactgtt aatccgatca tttcaattcc agcaaaactg aataaaacca
    13441 taggaaatga agcaatcatt ccagcaaagc caaacgggac taattcattg agctgtccaa
    13501 aatttgcttt gattccaata gactgggtat gaaaatctga gacactcaat cctataccca
    13561 ataagataaa aaggaaaatc cccaagatct tgatgattga gaaaaaagat tccaattcac
    13621 caaaccactt gactgcaaca aggttgactg ccattaagat cattagtgcg ctacctccgc
    13681 ttatcaaagc tggtacatgt acaaaccaga aatggatata caatcctatt gctgttaatt
    13741 ccgcaagtcc agctccaagc cagcaaagcc aataagtcca attgacaaaa aatgcccact
    13801 ttttgcctaa ataatagtca acgaaatcac tgatagagtt aaatgtacta tttgctaaaa
    13861 ataaatcacc catgacccgc atcaaaccat aaatagccaa accgcatatc aaataaacga
    13921 gaataacagc tggccctgct gatgcaattg cctttgctga acctaaaaat aatcctgttc
    13981 caattgcgcc acctaatgcg attaactgga tatttcgatt agttagagtc cgtttcattg
    14041 ccggtttttc catcaagttc acctttttct ttttcaagca gcatggcgac ttcctgttcc
    14101 caagaaggtt tctttatttt ttcaatacag agtggtacta caaacaaaat gacactgatg
    14161 gctgtgactg caattagatt gatccatgtc ccagctttca tcgtcagtcc gacagaaaat
    14221 ccgattgccg caaataaaac aataacgaca gtccaaactc caagattgct ctttttctct
    14281 ttttttccaa ttctaaatgg tcgattcaac tttgcatgtg tataacgcaa tctcaaaact
    14341 gcgatcccca tgatgacata gacgatacag tagataacag tagttgaatt tacgagcatc
    14401 aaaaatgctt gattgacgcc aggaatcagc aaataaaaaa gtgcaaagat tgagataatg
    14461 acagactgag tcaaaataac ggatttggat acgtcaaatt gattcgtctt ccaaaaattg
    14521 aattttggtg gatacgcacc ttttctagca ctttctgtca ctgtctttgc tggtcctgag
    14581 gcccaagcag ataattggac tgctacacca atgaagacaa gtaaactaaa cagattcaca
    14641 ataagatgtg gcaaaccaag aatttggcaa taaatcgaaa tagattgcgc gatattattc
    14701 aattccattt gtccttttgg tacgacattt gctacaacta aagcattcaa aatattgacg
    14761 aaaaatataa aaattaacgc ggcaaatact ccgcgaatat acgttttaac tggatttttc
    14821 aaccgagtga tatacacaga ggacatttcg ataccagtaa aaataaacat gatcggcgca
    14881 aaataaacaa atgaggatgc agtcgtagta tctggtatta atttgtccca tgaaaaactg
    14941 cctaatgttc cggttggtac gatcccaact ttgatccacg cagcaaaccc taataagagc
    15001 atcatcgtca aaggcacgta caatcctaac caaacaccga cttttccgcc gatttttgcc
    15061 atatcaaatt tcaaattcaa aaaagtgatg atccaataaa cgactaaaat gacaactaat
    15121 gtaaatttgc tgttcaaacc aagcggcaca ttatcgataa tattaccaaa caacggagca
    15181 agtgctgaag cgaccatcac catcccagga aacatttgga cccataacag ccatgagaca
    15241 acgaaccccc atttttttcc tagagcattc gatacccaaa gttctggacc acctttttgg
    15301 ggaaacattc cggcaaattc accagagatc aatgagattg gaaaagcgta caataatact
    15361 gcaaccagca tgtaaaaaat catcgtccag ctcgttgctg ctacatctgg aatatttcgt
    15421 acacttgcta caagggcgca ggtcattccg ataaaggtca tggtcgtgat ttgctttgat
    15481 gaaccagtat ctttcatctt tattccttct ttcaatagcg acatatgttt ttgttttctt
    15541 ttatttttgt tcaagaacag aaatgacaag gtttcatcga ttcagtacaa aacccagtat
    15601 caccgaaaca tccattgaac gatcttagtg aactgggttt gatacatgaa acgaacgatc
    15661 caacttatag aacgttttat aaaaaagaat atcttggcga ggaatatatg aaaaacaggg
    15721 ggaaatacaa ttgttttgat gaagcaaata attgtctgtt ctccatatgt ctcttgttat
    15781 tctttcacac aaaaatcagt tctattggat gatttcgttt agtttctttt ccattgcttt
    15841 ggcgatttct tttgtataaa aattgaaaat tcgatcatca ttcaaataag gagtcatgat
    15901 agccgcacgt agcagagtga ttttctgttc ttttttccat tcttctttcg ttagacccat
    15961 tctttcaaca aaacgaatcg gagaatcacc gtaatcttct tgtgtaaatg tagtatgaga
    16021 agtaataaac cgttcaccat aaacatcgcc atccatataa gaagaccgat cgaacatttt
    16081 ttcatttaat tcattgatag cgttcaaatc tgtacagcct tgttctttga atacccaatt
    16141 gaccatatta aaatcaggat gattcaatgg atagacttcg attgtttttc ctttaacagt
    16201 aaaagtcaga tgatcgagaa attctctgaa tctttgagct gcctcgattg aagccccaat
    16261 caattgacca tatccggtca cattcaatgg caatacacga tgtgctgtcc agactgcggc
    16321 ggcggttgct ccagcttttg atccttccaa aatataagct cctaacatat ctggagcctt
    16381 tactgatttt tcaaacacat atggcgcgaa ataagaaatg atatttctca tatttttatg
    16441 tttgattacg attcctccag cagcataagg gacatagccc atcttatgag gatctatcgt
    16501 gacagaatcc gcttctgaaa tagctctgaa cccttcatat acctctttgt caatcgttac
    16561 gcagtggtgg aaaacatgat gttcttcaaa gaattcagct aaggaagcat acggcacaaa
    16621 ttctcctgct tcgtttagaa acagtgaacg cgcatagccg ccatatgcgg catcaacatg
    16681 taaatagaaa tagatccctt catcttttaa cctttctctt aattggacga ttttatctac
    16741 actgtctact tgaccttctt ctgtcgttcc tacgacagca accacaccta gaattgggat
    16801 tttttgttca gctaattcac gaattgtttt ttccaaagca ttaatatcca ttcgataatc
    16861 ctcttgaact gggatagcaa ccatctgatc taagcctact ccgcaaatat ctaacgcctt
    16921 catccaagaa tagtgttttg tttgaggcac cagccatttc cctaatcttt ggatattttt
    16981 tccgctacgg gaagaagctg ctttgacctc atccatttct tcgtccgtaa agctttcggt
    17041 catttccaaa atttcttcaa cagataaatt caaaagttcc cactcagaca tttttttcac
    17101 ttgttcaggc agcacttcct tgacagctaa aggaatcgat ttgatgcagc gggcgtacca
    17161 taatccttca agattagcaa tagaaccatc tgctgcaatg tgtccccatc cgtctgtcat
    17221 attgaataat gaagcaaaat cctgtcctac ttctgcttcc atttgcgaag ttgccataga
    17281 agattccaat gcaacattat ttgggttcca cagcatcgca tagttgtaag ctaataaagc
    17341 aggcatcaat gtttcagcat tcatttgtcc ccagtaacgg cctgctgaat gccatgggat
    17401 cgatcctgcg cgtaatcgct gactgacttc atccaagacc tctatcatat ggtcgcgggt
    17461 ggctagataa tctggagtga gcttatctcc ttcgctaatt gcaggcatat ctgaaggaat
    17521 ataattttct ctccatccaa gatgttcatc taccatcttg ttcaacaaca ttttataaac
    17581 tggtccattt tcagctttgt cgcctataaa gacggccttg atatccatat ctttcatttt
    17641 tcttccctcc atattttgtt ggtcaatgtc tcgcagatac atgtgtttat ctgtaacacc
    17701 tcttcactat agcgccaaaa atgagaaatt tttttttata acatcaaatc cacgtagatt
    17761 tttaca
//
LOCUS       DAXLPY010000053        16615 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.053, whole genome shotgun sequence.
ACCESSION   DAXLPY010000053 DAXLPY010000000
VERSION     DAXLPY010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.053"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="ACF3UF_001947"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="ACF3UF_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFD3672044.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="ACF3UF_001948"
     CDS             complement(680..1666)
                     /locus_tag="ACF3UF_001948"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFD3672045.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="ACF3UF_001949"
     CDS             complement(1689..2255)
                     /locus_tag="ACF3UF_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFD3672046.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="ACF3UF_001950"
     CDS             complement(2269..2685)
                     /locus_tag="ACF3UF_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFD3672047.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="ACF3UF_001951"
     CDS             complement(3142..5076)
                     /locus_tag="ACF3UF_001951"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3672048.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5378..6313
                     /gene="pplA"
                     /locus_tag="ACF3UF_001952"
     CDS             5378..6313
                     /gene="pplA"
                     /locus_tag="ACF3UF_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFD3672049.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="ACF3UF_001953"
     CDS             6403..7506
                     /locus_tag="ACF3UF_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFD3672050.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="ACF3UF_001954"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="ACF3UF_001954"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFD3672051.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9407..10753)
                     /gene="gor"
                     /locus_tag="ACF3UF_001955"
     CDS             complement(9407..10753)
                     /gene="gor"
                     /locus_tag="ACF3UF_001955"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFD3672052.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10887..12140)
                     /locus_tag="ACF3UF_001956"
     CDS             complement(10887..12140)
                     /locus_tag="ACF3UF_001956"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFD3672053.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12146..13069)
                     /locus_tag="ACF3UF_001957"
     CDS             complement(12146..13069)
                     /locus_tag="ACF3UF_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFD3672054.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13290..15782)
                     /locus_tag="ACF3UF_001958"
     CDS             complement(13290..15782)
                     /locus_tag="ACF3UF_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFD3672055.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15789..16256)
                     /locus_tag="ACF3UF_001959"
     CDS             complement(15789..16256)
                     /locus_tag="ACF3UF_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFD3672056.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16392..16465)
                     /locus_tag="ACF3UF_001960"
     tRNA            complement(16392..16465)
                     /locus_tag="ACF3UF_001960"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16429..16431),aa:Arg,seq:acg)
     gene            complement(16523..16596)
                     /locus_tag="ACF3UF_001961"
     tRNA            complement(16523..16596)
                     /locus_tag="ACF3UF_001961"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16560..16562),aa:Pro,seq:tgg)
BASE COUNT         4908 a         3476 c         2956 g         5275 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgacc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg attgcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtctcg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttgc tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtgaaaaag tcgcttagtt tcgagtatta
     8761 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
     8821 aactggcttt tgaacaccgt ttatcagagg ttgtaaaatc agtgttttgt cctgagtatt
     8881 agagaaacaa atggaaaaat agttcctcat attttgccgt tttttgagct aataccgaag
     8941 gacagctgat tgaacactat ttgttcggaa aaagtgacta actatgacac aatttttttc
     9001 acagtccctt ttttcacttg atttgattcg taccagcgaa cttgacgaga actttcttgg
     9061 tttggtaact atatggtatt cttttaacat cctcgtttgc ttcttctaat ttatttatac
     9121 aaagtcacac ttttttaaac atctgttctt cgatacattt ctatttcttt taaacatcga
     9181 taccaatatt ttgaacttaa gagtgcatac caaatggatt catttactct tcgtcagtta
     9241 cgaagataat caaaatctcc aacttcccta cttatttcgt tttgagaatt atcgaagcaa
     9301 tcttacataa ataactaaaa aacaaaaaac cagaaaatca gtatactgat tttctggttt
     9361 tacatggttt gttcaataaa aagctgttgg aactgttaat attaaattat cgcatcgtta
     9421 cgaattcttc cgctcctgtt ggatggatgg ctactgtatt gtcaaagtct tctttagttg
     9481 cacccatctt gatagccacg gcaaaacctt gcagcatctc atcgacacca acaccaatag
     9541 catgtaagcc gacgattctt tcttcttttc cgacacagat caatttcatt tcgcattttt
     9601 ggcgataatc atttaatgca aagtacattg gggtaaagcg tgaacgataa actttcaatt
     9661 cattttcgcc atatttttcc aatgcttctt cttctgtcaa accaattgtt gcaattggtg
     9721 gatgcgtaaa gacgactgtc ggaacaagtt tatagtcaag ataagaatct ttctttccat
     9781 taaataaacg ttctgataaa cgtctaccag ctgcgattgc aacaggagtc agatctaatt
     9841 taccgatcac atcaccaaca gcaaaaatat gttcatccgt tgtattttgg tatttatcta
     9901 ctttgataaa cccttttttg tccaattcca catttgtatt ttccagacct aatttttcgg
     9961 tattcggtac acgtccaccg gcaaaaagta cacaatcacc agttaaggtt tcaccatttt
    10021 caaatagcac cgtatattcg tcattgtttt tagtaatttc tttagcaata tgatgtgcgt
    10081 aagtttttat tccagcttct tggtacattt ggatcaaatt gtccgaaagc attttatcaa
    10141 acgttctaag tggtcgttct tttcgatatg cccacatgac ttcactacct aaaccacaaa
    10201 atacacctga aagttcagcc gcaatgtatc cagcacctaa aacgattgct ctcttaggta
    10261 actctgttaa ttcaaaaaat ccatttgaat caattgcgta ttctccacca ggaatggtca
    10321 ttttacttgc acggcctcca gtagcgatca agattttagg agcacgatag gtttcaccgt
    10381 ttacttcgat cgtttgacta tcgataaaag tagcgtaacc ttttatagcc tcgacatgat
    10441 tgctatctaa tcctctttga taagcaccgt gtagaaaatc aatatatttt tctcgtcttt
    10501 ctactagacc ggcgaaatca acatttttta aatctgcttg gataccgtaa cttgaggcat
    10561 ctcgttcaat tgtttccaaa atcgtacttg cttgccacat aactttttta ggtacacaac
    10621 cgacgttgac acatgttccg cccaattcat tcgcttcaat cagcaaaact tttgcgccat
    10681 gcatccctgc tctgtttgct gaagcaatac cgccagagcc gccaccaatt acgatgtaat
    10741 catatatttg cattttgttc ctccttattg aagagatcaa tcaaaacctt tatttaacga
    10801 tcctttttct acagaaaaca agtgtaacac ttttcttgaa ttttgtatgc gaagatgctt
    10861 aaaacaggga tatatcagct ttttccttat ttacgttttc ggatcatatc tccaggtttc
    10921 accggctgtg cgactggcat agttaaaatc atcattggat ttggtgctcg gtcaatggat
    10981 tcgccttctt cattatgcat aacttcaacg gtttgactga aatgactgaa tcctggacca
    11041 taaaattcga tttcatctcc tacagaaaac aagtttctct gacgtatcgt agcaatctgt
    11101 gttgcctcat cataagataa tacttcaccg acaaatttat atactgggat tttacgacgt
    11161 tcaccgaata attgttcgtt ttcagttggt gtattgtagt aaaaacctgt agctaattct
    11221 cgttgtgcta ctttccataa ctcgtcgatc cattcttgct tgcagacata gttttcagga
    11281 tcttccatat aactgtctac agccgcttta tagacatttg acaccgtaga tacataatgg
    11341 atcgatttca ttcttccttc gatcttgaag ctgtctacgc cgttttcaat caattctgga
    11401 atatgttcga tcattgacat atccactgca ctcatcgaga attcttcttc cacttcgcct
    11461 gtatcagtta aactgtttcg ttcttgacca aaaggcatat cgaacaatcc atacttccag
    11521 cgacaagatt gagaacatcc gccacggttt gcatcccgca tcgacatatg gttggacaat
    11581 gtgcatcgac cagaataaga gatacacatg gcaccatgga taaatgcttc gatttcggta
    11641 tccgtatttt tacgaatctc tgccacttcc tccattgaaa cttcacgagc taaaacgaca
    11701 cgttccaacc cttcttcttt ccagaattcc aatgtctcaa aattagttgc tgaagcttga
    11761 gtggataaat ggatcggcag acctggggct tctgtcgcac aaatttcgat caaagctgga
    11821 tcagaaacaa tcactgcaga aataccgaca tcacgcaaac tgcggaaaaa ttcccctgct
    11881 ccatcttcat ttccttcatg ggtgaccata ttagcagcaa cgtatacctt cgcatcatgt
    11941 tcttttgcaa aagcaactcc ttcagccatt tcttcataag taaaattacc tgcacggctt
    12001 cttaaaccat atgcattccc gccaatatat actgcatctg ctccataatg gatcgcggtt
    12061 tttaactttt ccagtgttcc tgctggcgct aggatttctg gtcgtttcaa ttttcttttt
    12121 actgtcattt ctttcatcat actccttatt tgatagcaga aggatcaata taaaagaatc
    12181 ctgtatctaa ttcacggttt tcaggatgca atttactgat ttcgctagtc attttttccg
    12241 ctttttcttg atcccagcta ccttctaaaa tttgtttttt tgcttcggcg aatagtcgag
    12301 tgatgtttac gaatttttcg cctggagtaa ataatccgtc caatttccat gtacagtaat
    12361 gatgctgata aagttcattc aattcattcg agagattcag atcattgctg gcaaaaatat
    12421 gtgtgccatg actatcttca taaatagaat aatgtgtctc ttctttttta ggttccgaga
    12481 taaaaagacc tctttcacga tctttttgtt cgtcttgttt cgtatagtta tagtaattct
    12541 gtagcagtgg acgtttggat tgatggatgc atgtagcacc atacacaagg gtttctacag
    12601 gaatatcgag tttttcttcc atcgccttca tctcttcaaa aggaacttca cgagcaagta
    12661 ctgctccaac tgcgcctttt ttcgcccaga aattgatttg acgtgcgctc gttactaatg
    12721 tttcagcatc ataaatatac ggtatacgca attcaggatt ttttttcatc gtataaataa
    12781 tacctgtatc accaactgtg atcacatcta cgtttatttc ttttaaaaaa gccaaatatt
    12841 caggtacatt tttcattttt tcaggatgaa tgatcccatt tacagcaata ttcgcttttt
    12901 taccatactt gtgtgctaat tctaccaatt gtcgctgttc ttctcgtgta aatgaagcag
    12961 gcagacgcaa tccaaattgc tcttcaccga aatatagtgt atctgcacct gcagcaagca
    13021 actgttctgc ttgttcaata gtttctactg tggttatgag ttcgatcata attttctcct
    13081 cctacaactt cataatagta gcatagctct aaaaactttc caatacttct tctatttaaa
    13141 gtcggatttt tgaaaattat ttcacaaaaa atcaaaataa agttcgatat attctgtcca
    13201 aatataaaaa gagattgtga caaaaatctt gtcacaacct cttaatcaag tcttactatt
    13261 ataaaaattc agctacacag gccaagtaac tatagggaac ctactgtttc ctttttaggt
    13321 ccgcgaacat tcaatgtgat cttacctttt gaagcaccta ctgttacgtg gtcacctaaa
    13381 cgaatttctc cgccaagcaa agcctcgctc aatcgatctt caatttcttt ttgaagtgcg
    13441 cgacggattg gacgtgcacc atattcagga tcaaatccag ctttcccgat cacatcgatt
    13501 gcagatggtg tgattttcac ttgaatatct tgttctttca atcgtttgat aatcgctttg
    13561 ctcatgattt ggacgattgt atggatttca tctttactca atgaatggaa gacgacagtc
    13621 tcatcgattc gattcaagaa ttcaggtcgg aaagctttct ttaactcttc taagatacgt
    13681 ttttgcatgg ctttgtgatc tttagtaaca tcttggacat tgaatccgac atttttttct
    13741 tctcgaattt gtgtcgctcc gatatttgaa gtcataatca tgattgtatt tctaaagtcc
    13801 acttttctac ctttagaatc tgttaaatga ccatcatcca atacttgcag aagtaaattg
    13861 aaaacgtctg gatgtgcttt ctccacttca tctaagagaa tcactgaata tggtttttga
    13921 cgaatttttt ctgtcaactg tccaccttca tcatacccta cgtatcctgg aggagacccg
    13981 attaatcggc ttgtactgta tttttccata aattctgaca tatcaacacg gatcagggca
    14041 tcttcacttc caaacatgac ttctgaaagt gctttggcca attctgtttt tccgacacca
    14101 gttggtccaa ggaacatgaa tgaaccaatt ggacgatcag gatctttcaa tccgcttcgt
    14161 gcacggcgga tcgcacgtga aactgctttg acagcctcat cttgaccaac gacacgttca
    14221 tgcagaagtc cttccagttc taacaagcgt tcgctttctt ttttctccaa ctgctgtaga
    14281 gggacaccag tccactccga tacaactgta gcaacatctt cttctgttac acgatcagaa
    14341 taaccttgct cctgttttgc ttcaattgca gaaacttttt gcagcttttt acgtagtgct
    14401 ttttcttgtc tgcgtaattg agcagcattt tcaaagtctt gtttttggat cgctgcttcc
    14461 ttttcttgta ctagttcatc gatttctagt ttgatcacag ttgattttgt taagtgatcg
    14521 gtttgatcca aacggacttt cgctgctgat tcatcgatca aatcaattgc tttatcgggt
    14581 agttgacgag aagtgatata acgaacagaa agattgactg ctgctcgtac agcttcatct
    14641 gtgatctcca ctccatggtg ctcttcatat cttgtacgta atccttgaag aatcacttct
    14701 gcttcttcag gagttggctc atctacttga atgcgagcaa aacgtcgctc taatgcagaa
    14761 tctttttcga tatatttttg atattcatct agggtcgttg ctccgatcgt ttgtaattct
    14821 cctcgagcta acgccggttt caagatattc gaagcatcaa ttgctccttc tgctccacct
    14881 gcaccaatta aggtatgcaa ttcatcaatg aataagatta cttgaccatc attatagatt
    14941 tcgtcgatga cctttttcat tcgatcttca aattcaccgc gatatttcgt accagcaacc
    15001 aaagatccca tatcaagcat catcaggcgc ttttcttgca tgtcttctgg cacttcacct
    15061 aaaatgattt tttgagctaa cccttcagca atggctgttt tgcctacacc aggttcaccc
    15121 accagtacag ggttattctt tgtccgtcgg ctaagaatct ggataagccg tttcacttct
    15181 ctcgaacgac caacaactgg gtccagcttg ttttcttttg ctaatttcgt caaatcacgt
    15241 gctaatgaat ctagcgtagg tgttccttgc ggtgtttgcc gtttatcttg tacatttaca
    15301 tttctacgac gattcattcc ttttccagca gaatcaccag ctagccccat tttttgtttc
    15361 agaacttgac gggcttttga aaggctgata cctaagttga tcatgattcg agtagccatg
    15421 atactttcat cttttaataa gctcatcaaa atatgttctg ttccaacttt ttgagaacca
    15481 gttttcttca cttcgctgct agctaaagca aaaacttgtt tcattcttgg tgaatatgga
    15541 agaaagactc ctttagggta agaacggata ccaccataac caatcagatg ttcaatttct
    15601 tcataaattt ccgtttcatt caaatccatt tcacgtaata cttttccagc aattccattt
    15661 tgctcgacca ctaaggctag taaaacatgt tctgaactaa ctgattgatg tttcaaccgt
    15721 tttgcttctt cttgtgcaat ttctaatact gcttgggctc tttcagtaaa aagttcttcc
    15781 atctaatctc acttcccatc ttcataactt aaacgttcca gaaatgctcg gagaatccga
    15841 gcacgtgtat gatcttcata ttcattgaaa ttcaatgtgt tttttgcaat tgcactcaac
    15901 atcaagtttc cttctttttt tgtaattatt tggtcttcat aaagtttttg aataatagca
    15961 aaagcatttt tctcactgat tgtatcatca aataactgat ttatctgctc aagtaattgt
    16021 tttttatctg aaatccttac ttttgcaatt cgtatataac caccaccacc acgtttgctt
    16081 tctactagat aaccacgttg gatggtaaaa cgggtattaa tcacatagtt gatttgtgaa
    16141 ggaacacagt taaagaggtc tgccatttca atccttcgaa tctcgatcat ttcactattt
    16201 tccagaattt tctttatata tgattcaatt aaatccgagg tattctgatg tgccatctta
    16261 ttcattccct ttgactaata ttgaccttaa ttataacgaa tttgataata gaaagaaaga
    16321 agaacgcttt ttgttaaata aatcctttag aatcaacaaa aaaaaatacg gaatatacta
    16381 ttccgtatcg acgcgcccaa gaggagtcga acccctaacc ttttgatccg tagtcaaaca
    16441 ctctatccag ttgagctatg ggcgcatatt caatttaaaa aaattataaa tcatttgaaa
    16501 acaaaaagca agataaaaaa aatcgggaag acaggattcg aacctgcgac cccttggtcc
    16561 caaaccaagt gctctaccaa gctgagctac ttcccgttta aaaaataaaa aagac
//
LOCUS       DAXLPY010000054        15937 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.054, whole genome shotgun sequence.
ACCESSION   DAXLPY010000054 DAXLPY010000000
VERSION     DAXLPY010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.054"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(174..476)
                     /locus_tag="ACF3UF_001962"
     CDS             complement(174..476)
                     /locus_tag="ACF3UF_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFD3672057.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(696..1062)
                     /gene="ssrA"
                     /locus_tag="ACF3UF_001963"
     tmRNA           complement(696..1062)
                     /gene="ssrA"
                     /locus_tag="ACF3UF_001963"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1233..2006)
                     /locus_tag="ACF3UF_001964"
     CDS             complement(1233..2006)
                     /locus_tag="ACF3UF_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3672058.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2150..2500
                     /locus_tag="ACF3UF_001965"
     CDS             2150..2500
                     /locus_tag="ACF3UF_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFD3672059.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2481..3197
                     /locus_tag="ACF3UF_001966"
     CDS             2481..3197
                     /locus_tag="ACF3UF_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFD3672060.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3197..4645
                     /locus_tag="ACF3UF_001967"
     CDS             3197..4645
                     /locus_tag="ACF3UF_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3672061.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4715..5224)
                     /locus_tag="ACF3UF_001968"
     CDS             complement(4715..5224)
                     /locus_tag="ACF3UF_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672062.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5214..5938)
                     /locus_tag="ACF3UF_001969"
                     /pseudo
     CDS             complement(5214..5938)
                     /locus_tag="ACF3UF_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6161..8281)
                     /locus_tag="ACF3UF_001970"
     CDS             complement(6161..8281)
                     /locus_tag="ACF3UF_001970"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD3672063.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8511..9689
                     /locus_tag="ACF3UF_001971"
     CDS             8511..9689
                     /locus_tag="ACF3UF_001971"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFD3672064.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9705..10463
                     /gene="aroD"
                     /locus_tag="ACF3UF_001972"
     CDS             9705..10463
                     /gene="aroD"
                     /locus_tag="ACF3UF_001972"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFD3672065.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFFSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10486..10971
                     /gene="ybaK"
                     /locus_tag="ACF3UF_001973"
     CDS             10486..10971
                     /gene="ybaK"
                     /locus_tag="ACF3UF_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFD3672066.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(11042..12295)
                     /locus_tag="ACF3UF_001974"
     CDS             complement(11042..12295)
                     /locus_tag="ACF3UF_001974"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3672067.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12412..13761
                     /gene="gdhA"
                     /locus_tag="ACF3UF_001975"
     CDS             12412..13761
                     /gene="gdhA"
                     /locus_tag="ACF3UF_001975"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFD3672068.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13873..15219
                     /locus_tag="ACF3UF_001976"
     CDS             13873..15219
                     /locus_tag="ACF3UF_001976"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFD3672069.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(15527..15913)
                     /locus_tag="ACF3UF_001977"
     CDS             complement(15527..15913)
                     /locus_tag="ACF3UF_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3672070.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5216 a         2844 c         3191 g         4686 t
ORIGIN      
        1 acttataatt ggagtggtag ttaattagtg acttattttt gattttatag cactgatact
       61 ataaaatata gatatcatca tattacacaa tcttaatact aacttaaaaa atatcccttt
      121 tataagtatg gtgataaaat ccgttccggg ctaccttttt taggtagcct actttaatct
      181 ttataccttt ctggatcaac gaaagtatac ttcaaatagt cataacgccg atgatcgctc
      241 cgtgcgtctg gcacatcagt cacgatatca aacaaaaaat acacatcttt cttcattctg
      301 gtttttgttg ccggaatttt aaagtagttc ttattagagt aatagagatt gattaataag
      361 ctatcttcga ttgctaaaaa gaaaacttct gaatcccaca ccttataaaa atctttgaca
      421 aatctattcg aaggatcaaa tttaaaccat aattgtgttt ttccttccat caacataatg
      481 ttcacctcaa aaagagtata cgaactaatg ttctttttgt aaagtaggaa tatcattgat
      541 aatatggatg gaacatatat attaaaaagt gttctttttg aatgctattt tgaatgccat
      601 tttcattcat ttaacgaaaa tctgcgaaaa taaaaaatgc tcaaaccctt ataaaataag
      661 gatttaagca tctagcgaaa tctgctgaaa tctcacaatg gagacggcgg gagtcgaacc
      721 cgcgtccaaa cacatcgcca cttaaaaatc tacgttcata gtcaactcat ttaaggattc
      781 actttacagc ttgccgagtg acaggcattc tgtatcgcta gtctgatgtt ctctttttca
      841 acttacagac ggaaagttga aacgtatccc actaaagtta ggacccttac tcgagcacat
      901 gggcgatgcc gagaggatct acgctaactg tttttaggca gctaaagcgt aagagttgtt
      961 ttcgttttta gcagttatat ttaactgtaa cgtttttacg tagacgtaac ctacgaaacg
     1021 caattcaagc tcgactgtgc ctgtcgaatc cgtaacgtcc ccgttagcta acaagggtta
     1081 cgtgtatttt tcatacaaaa ttagtatagc atatattggg ataaattcaa taaaaaagcg
     1141 aatcatatcc cattatttat ataataactg cccctttctt aagaaaaaat aagcgatttt
     1201 cttaagaaaa gaggtagctt caaaaaaaga tcttaaatca gatcaaaata cttcaatgcg
     1261 tggacaattc cgccttctgt atttttcttt gtgataaagg tagaaagttc ttttaatccg
     1321 tcataggcgt tgcccatagc gattttgttg tcgcaagctt ccaacaaggc aaaatcattc
     1381 ggaccatcgc caaatccaaa agtaggaact ttttccagct gaagttcttt ttgcagacgt
     1441 ttgacacctg ccccttttga gattcctttc ttcactgtat cgatcgagta aggaccattc
     1501 cgataaaaag ttagctcagg aaaatgttcg tgatagtatt cgtcacctga ttgagataag
     1561 atcagcaaca tatttactgt gttttcttta aagcctaaag gatcaatttc cggaacatct
     1621 gaatgaatga agtcgtaagc attgatcatt gtttggctat gaccggtaca ccagattttc
     1681 tgatcgttat agtaagaaag ttcatgaccg ttcaactgta catgatcata cattttttga
     1741 cattcttctg aagaaaatgt ttgagaatag atttcttcgc cgtctactcg aatgaaagaa
     1801 ccattcatgg tgaccgcaga agtaatgccc gcatcttcca tgatagagtg gatttctgct
     1861 tctgtacgtc ctgtagcgat gacggggaga acattgtttt cttttaatgc gttcatagct
     1921 tttgccactt cgggtgtgat ttttgatttc gcatctagta atgttccatc aagatcaaag
     1981 aaagtgattg cacgataatt tgacacaaat aaaactcctt ttttattgga ataagtttat
     2041 cttaacaaag aatgaacaaa agacaaacct ttcgtgaaga attcctgaac atattggttc
     2101 agtcaacaat ttagagtata ctataagaag agaatttagg agggaaagaa tgattttttt
     2161 cagtattggt atcttattct taataattgg cagtcttttt cggattctgc cctcaaaagg
     2221 aaatctgcct ttttatgggt atcattcgcc tcttgccgca aaaacagacg ctcattggcg
     2281 gctggctcaa aagacaagcg gaaactggtt ttttcttatg ggcttactga tggcattgat
     2341 cggctattat ttaaagacat ctgggcatac gaattatttt ctgattgaaa tgcttctgct
     2401 agtatttcca attatgccta tttttattat gacagaaaag aaattacaga aatatgacct
     2461 ggaaactgga gggaacgata atgaatattt taatgattga agataatcaa tctgtttctg
     2521 aaatgatgca gatgtttttc ttaaatgaag gttgggaagc aactttcaag tatgatggaa
     2581 aagaagggct cgatgccttt ttagaaaacc cacaacattg ggatatgatt acactagacc
     2641 tgaatttgcc cacactggac ggtatgctag taggaagaga gatccgcaaa gtttcaagta
     2701 ctgtgccgat tatcatgctg acagctagag attctgaaag cgatcaggtg atcggcttag
     2761 agatgggggc agatgattat gtcacaaaac ctttcagtcc tctgacgctt attgctcgaa
     2821 tgaaagcttt gcatcgccgt agtgagttgg cagaagcaag agaagaagca gtagtttcag
     2881 atgatcattt tgatatcgag actagtcatt tcaagatgaa tacgaaaaca cgagaagcgt
     2941 atctggacaa ccggccaatt gaaggactga cgcctaaaga gttcgatcta ttgtttactt
     3001 tagcaaaaaa accacgtcaa gtattctctc gggagcagtt gcttgaatta gtctgggatt
     3061 atcagtactt tggtgatgaa cggacagtgg acgcccatat caagaaatta cgacaaaaaa
     3121 tcgaaaaggt cggaccacaa gtcatccaaa ctgtttgggg agtcggctac aaattcgatg
     3181 attctggtgt tgcctaatgc gttatttgta tcagcaactc ttagctttct gcggaatggt
     3241 cgcgttgatc ttattgatcg ttggagtttc ttttacacaa ctgacaaaac aaacgattga
     3301 agaaaacaat taccagcaac tgtttggata tgctgaatca gttgaaaaga caacgcaaac
     3361 ctatgccgat acgctcccgc agtttagtca agatcaggcg tttcaaaatg cattgctgct
     3421 gacagagcaa gtactgacag aacaaaatgt gaactttata tttatcgata aaaacgaacg
     3481 tgtcatttat ccgactaata cagctttact gaattttacc ttaacagctg atcaatggaa
     3541 aaatctgagg aatggacgtc aagaaaaatt cacatcgaat aaaaatattt taggacaagc
     3601 acaggcgacc tcttacgcac ttgtgccatt taatttgaat catgaattct atggagcact
     3661 tgtagttagt caacctgcgc gaaatatcga taacagcgtt cgtccaatta cactgaacct
     3721 gttcaaagga tttatttttt ccagtatcgt tgcagttatt gccagctatg cttttgcagc
     3781 attccaagtt aagcgtatca atcggttaag gaatgcgacg aaagaagtga cgaatggtaa
     3841 ttttgatgta cagctccccg tacatgacaa agatgaattt gatgagttag cagatgattt
     3901 caataaaatg acgaattcat tgaaagaatc tcaagcagaa attgaagaac aagaaaatcg
     3961 tcgaagacaa tttatggcag atgcttctca cgagatgaga acacctctta cgacaatcaa
     4021 cggacttctg gaagggttag aatacaatgc aatccctgaa aatcagcgag aaaacgcgat
     4081 taaattgatg aaaaatgaaa cagagcgtct gatccgtttg gtgaatgaaa acttggatta
     4141 tgaaaaaatc cgtacgaatc aaatcagtat ggtcattaaa aaattcaatg gaacagaaac
     4201 attgaaaaat attgttgcac agttagaagc taaagcagaa gcagcaggag atacattgac
     4261 attgaaagcc gttgatgata ttgatgttta cgctgattat gaccgatttg tccaaatcat
     4321 ggtcaatatt attcaaaacg cgatacagtt tactgaaaac ggccaaatca cgattacttt
     4381 agaaaaaggc tatcttgaaa cgatcatcac gattgaagat acgggaattg gaatgtctga
     4441 acaacaaatg aaaagtatct gggatcgtta ttataaagta gatccttcaa gaaaaaatac
     4501 aaaatatggt gaatcaggat taggtttacc aatcgtgcag caacttgtac gcttgcataa
     4561 aggaaaatta gaagtagaaa gcgaactagg aaaaggaaca aaattcgctg ttcgtttgcc
     4621 tgacgtagaa atcaaaaaag agtaaaaaac aagcggtata aaagatcatg aatcgatctt
     4681 ctataccgct tgtttttact ataaaatgat tgatttagcc cgcgggctct aaacgatcaa
     4741 tataaggact ttgagcaata gtagcatcat gagtaaagag taagatacct tgattttctt
     4801 catgagctaa ataagaaagc aagtggagta gctcttggat ctccaataca ctaagttcat
     4861 caaatgtatc ttcaataaca atattgtttc gcttggaaag caaggcatga agtaattgca
     4921 gctttacttt ttcaaaagac gtcaactcag ctgccgcaca attaagcaag gaaggagaga
     4981 tatcaagttt ttcttgatag gccaaacgat cttgtttgat ttctttttcc ggtacatcca
     5041 acaggacatg gtctttaaga ttcagataag gaaacatcgg ccaatttttt tggatgatcg
     5101 caaaattatc cagttttgca acaagaacct cttttttcaa gtgctccaat attttatgct
     5161 gtttttcgag aggacacaaa ataacggtca agtgttcagc atgaatcaaa tattcaggtt
     5221 tcattacgtc caggcctcct actttgcaaa tgatggataa aaaagtgaaa gggaatagac
     5281 taagaatgag acagcatcca ctgagcccaa taagagtttg ggcaaatccc ttaagtatat
     5341 ctgtgaaaaa aagatcattt tggaaatcga tggtaaaaaa agtctgttga tccatcggaa
     5401 ttgtaagtcc gcttaccgaa gtcaagatat cacggatatc tggcagttca gtagtcttta
     5461 agacaagaaa attgatcctt tgaagaagcg cttcataaac tgactggaag cttacgatcc
     5521 acaataaaac caagatacaa caaagaaaga gaggaaagaa cagctgccag aaaataaaaa
     5581 ggaataattt ggttttagaa agaccagtca ggtgccaatt gatcaattcc tgcttgtttt
     5641 gcctgactga atagtaaaag aaaaagataa aaaggaaggc aaatagaaaa aataaactga
     5701 atatgccttt tatataaaat cggctagcta attctaaagc cggaagaagc tctgtagatg
     5761 cagaagcgcc aataaatgaa agccgatctt ggacttgatt ggctaaagcc gattgcaaat
     5821 ggtaaagagt caggcatgct atcaataaaa aagcagaaaa gcttgaaaat aaacaataga
     5881 gtattgtctg ctttttgtaa taaattaatc gagcagtagc atagcggatt attttcatac
     5941 ttttcacctc tataaaaagt atagaaaatg aatatgaata aagtatgaaa ttcctttagt
     6001 gaaatcacga attaaaacca gaaaatattt tgtaaaaagc aagaggttgt gaagaagctg
     6061 ccctattcta ttaccgtaga tgcaagcttt tgaacactgt ttattcgaaa agaggagcag
     6121 cgacaataat tttgtcgctg ctccttttaa atttatttta tcattcggaa gaacttgtgg
     6181 tcgttccgtg aagttcttgg tacgtttgcg ttttataaag atcaacagtt gattgtccgt
     6241 tgtgttcact aaagacacta gttgacttgt caccaagaga tttttcagct tcttttaatt
     6301 tctctaagcc attcttgtag tcataatcac tggtatcaat tgggtctaat ccactattcg
     6361 tatagaaccg aagaagatca ccattattga tttggtcaga aacagctaac tgtttatcaa
     6421 ctttttcttt cagtgaatca atttcattct gtacttcctc agtaggttca gtaatagctt
     6481 caccagtttc gttactatag atcgtaccac cgtagtaagt atattttggt gtaacaaaat
     6541 caccatcacg gaaagaaaca agctgttcat gatctttcga gaatagatct tgtcctaact
     6601 gaatataatt ttttgtatct acacctagta agtgaagtaa tgtaggcaag gcatcaactt
     6661 gtccgccgta agtgtgattg attccgccct gtgtttgtcc agggatatgg atcatataag
     6721 ggacacgctg catttgtgca ttgtcgtagt ttgtccaagt agaacttgtt tttccaacta
     6781 attcagctag atttttattt cttgaattcg agacaccgta atggtcaccg taaaggacga
     6841 tgactgaatt atcatacaag ccgctttctt tcaaataatt gaagaattct tgtacggcgg
     6901 tatctaaata attggctgtc gcaaagtaac cgttgatcgt ttcatcattt gtattggcta
     6961 acgggaatcc tgcttcgtca ttggtgaatt ttgaataagg ataatggtta gatacagcaa
     7021 tgaattttga ataaaatggt tgttgcagac gttccaagta ttgtacggat tgttggaaaa
     7081 atggtttatc atgcaacccg tattggaacg aattgtcatc attaacatca taataagaag
     7141 aatcaaagaa ataatcatat cctaaattct tgtatgtctc gtttcgattc cagaatgtac
     7201 cagcgttccc atggaatacc gcactaatgt aaccttgtgt ttgacttaaa atatcaggtg
     7261 cagcttggaa agtatttttt ccgcctaatt gtgtgaacaa ggagccttga ttcaagccaa
     7321 acaatgaatt ttccatcagc gtttccgcat cgcttgtttt tcctgctttt acttgatgga
     7381 aaaagttgtc aaaactgaac gtgctgttgc tgtggtaaag actattgatg aaaggtgtaa
     7441 cttcatgctg gagaccattc tcatctgtca atttataatc gatcaggaat tgctggaagc
     7501 tttctaaatg gatataaatc acattttttc ctctagcgag cccgaacaaa tcgtcatttg
     7561 gtgctgcata atgttctttt acataatttt ctacttcttt catatcattg ggacttgctt
     7621 ctgcccgcac ttggtttgtc tggtaagttt gaacaccgtc ataaaccatg aaagcattca
     7681 agccaagata tttgaccaaa taatcacgag agaatgttcg agtcagcaat tctggacgat
     7741 cagcttccgc cataaaaaga tttcctgaga aaatcataac tgctaatgta gagatcgcaa
     7801 aagccattct tgctcggatc gggcgagggt ccaacttgat tttttttgca atcagcagaa
     7861 cagtcaagat aataaaatcg atccaataga tcacatcata tgggcgaaac agtcgaatgg
     7921 cactttctcc cagaccactc gctactttcc cagcacctaa aatcgtgttg atcgtaatga
     7981 agtccgtgaa ttctcgataa taagtgacat tcgaaaaaac aagcaatgtc aaaagaaaat
     8041 aaatgaccat catcgtgata taagcaactc tagggcgtct gatataaaga gcaattccaa
     8101 gtaataacaa tgtagttgca atagggttga taaacaagat aaagtattga atgccacttt
     8161 cgattccgag atggaaatca actaaatagg caaaaatcgt tttcaaccaa agtaaaacga
     8221 ctagtaaaga aaaaaatccg agcctcttat tcaaaaaggc aggtgttttt atacatttca
     8281 agataatctt cctttctgca cttcttaatc acagaagtgt cctgaaacca tgttacacag
     8341 ctcacttatt ctcatttatt ttactagtat gacaatatag tgtcaattga aaccagaagt
     8401 ttatgctgtt tcattaaggt tttctttaag cttcatgaaa aaatgagcag taagacaagt
     8461 cctatgtttt ttgttatact tgggaagaga aagctaaagc aggtgaagga atgaaagtaa
     8521 aagtaaaaaa aagagcaagc aatcgattga aaaaaggata tccactgatc caaaaagaag
     8581 accttgctca tccccaaaaa gaaaccacgc aatgggtgga attagttgat tcgcaaaacc
     8641 aatttatcgc aaaaggatat ctaggaaagc agaataaggg aatcggttgg gtattgagcc
     8701 agcagaacat cccatttgat caatcttttt ttgaagaatt ttttgtgaag tcaaaagaaa
     8761 aaagaacttt ctttttttca gatgattcta ctaccgcttt tcgtatattc aatggagaag
     8821 gagacgggat cggcggtctg attgttgatt attatgcagg ttatgctgtt ttttcttggt
     8881 ataacgaaac gttatatgca catcgtgaat tattgattca agcttttcgt gaaatctacc
     8941 cggaaatcat aggaggctat gagaaaattc gatttgaatc agtaaatctg cctgagagcc
     9001 agttcattta cggaaaagag gcaccggaac ccttgatcgt aaaagaaaac ggagtaaaat
     9061 ttgccgttta tttaaatgaa ggattaatga ctgggatctt tttagaccaa aaagaagtac
     9121 ggggatcatt agcagaaggt ttcgcttctg ggaaaacagt tttgaacatg tttagttata
     9181 ccggcgcctt ttctgttgct gccgcaatgg gaggggcaat cgaaacaaca agtgtcgatc
     9241 tagcaaaacg cagtttaaaa aaaacacagg aacagtttga agtgaatggt ttggatgtcg
     9301 atcagcaaaa aatcattgtt atggacgtat tcgagtattt caaatacgcc aaaagaaaac
     9361 aatttttata tgacatgatt gtattggatc caccaagttt tgccagaaat aagaaaaaag
     9421 tctttcgcgt agcaaaagat tatggggaac tggtcaagga tagtctggat attttagcag
     9481 aagacgggat acttattgcg tctacaaatg ctgcgaatgt ctcgatagaa caattccaaa
     9541 caatgattga agaggaattc catgccaaaa atgtttcttt tgaacaactt gctttatatc
     9601 gtctgccaaa agatttccag acgacggata cctttttaga aggcaattat ctgaaagtgt
     9661 ttgtttatca aattaaaaat aaccattaga aggagcgatg cagaatggtt cgggtaaagg
     9721 gattgaatat aggaagcggt agaccaaaga tttgtgcgcc tcttatcggg gccgtccgag
     9781 aggaagtatt acgtgaagca gttcttgcac gtgaagcagg ggccgattta gtcgaatggc
     9841 gagtcgatca ttatcgtgaa gttttttctt ttgatgaagt agcagaaaca ttggttctta
     9901 tccatgagat gcttgatgga ctgccgttat tatttacgtt tcgtacctta gctgaaggcg
     9961 gagaacaaga catatcgatc cgtcagtatc gcgaccttta tgaacatgtg atacacacag
    10021 gattagtaga tatggtcgat atcgagttgt tcaaagtaga aagtctagga aaaagactga
    10081 tagaggaaat caagtcttta aacattcctt taattatcag tagtcatgat tttaaagaaa
    10141 caccagcaga ccctgtcttg ctttaccgat tgaatgttat ggaacatttt ggagccgata
    10201 tcggaaaact ggcagtaact cccaataatg aacgagatgt tttgcggttg atggagttga
    10261 ctagacgggc aaatgctttt ttctccatgc ctattattac gatgtccatg ggaaatcttg
    10321 gtaaaatttc tcgtctggtt ggcggaacga cgggttccgt tatgacattt ggttccttaa
    10381 gcagcgattc tacttctgct ccaggacaat taccggtcaa agcattgaag caaattattc
    10441 aattattaaa tgaaccgttg tagaacaagt ttgaggtgat attttttggc aaagaaaaaa
    10501 atagtaaaaa cgaatgcaat ccgtatggtc gaacaaaaaa agattcccta tacagagcac
    10561 gaatatgagt gggacgaaag ccacctaagt gcgtcatcgg tcgctgaaca gcttccagaa
    10621 agccaatctc gtatatttaa aacactggtt gctgtgggca atgtgacggg gcctcttgtt
    10681 gctgtgatac cgggagaagc cgaattgaat ctaaaaaaat tagcaaaagt ttcagggaat
    10741 aaaaaagtag aaatgctcca tttaaaagat ttggaagcaa cgaccggata catacgtggt
    10801 ggctgctcgc ctataggtat gaaaaaacta tttcctactt atttagatca aattgcagaa
    10861 agctatgaac aaatcattgt ctcggctggc agaagagggc tacagatgga gttagcacct
    10921 caagatatct gtgcattaac gagcggacaa tttgcagata taaaacaata aatcatacgt
    10981 ataaaagaaa gaaggaggcc gggatgttgt ttgtccagtc tccttctttc ttttttatac
    11041 attatgctct ttgcccggca ttcattcctg ctacatgccc tgtagcgaaa gccgctgtga
    11101 tattaaagcc gccagtataa ccattgacat ccagtaattc tcccgcaaaa tacagaccat
    11161 caatgatttt actctccaat gttttaggat aaatttcctt tagagaaacc cctccgccag
    11221 ttacaaatga tttctcaata ggaaaagttt tgttgattga tagcttaaac tctttgcata
    11281 gttgaacaaa atcttgaatt tgtttttgag aggcttgttg tcctgtcaga tgatccattt
    11341 caagccgctc aagaaagaaa actaacaatc gctcaggcaa tataccatgc caagcattga
    11401 ccaagttctt tttggttgct ttactttttt ctgtcaatat atgaataagc tcttgtttgg
    11461 tttgtgtagg gaaacaatcc agagaaagtg tcactggttc tcccgttttc tctaattctt
    11521 tattgacaaa acttgaacaa cgcagtgcag ccggaccaga aataccgaaa tgggtgaaaa
    11581 gtaaatccat cgtatgttca gtcaatacac gacctttttt atttaaaacg cgtaaagtga
    11641 tgtcttgtaa agaaagccct tgaagtgttt tctcctgaat atacggttca tccgatatca
    11701 agggggactc tgtcgcataa agaggcgtca ccgtgtgacc cactcgcttc acgatcttgt
    11761 acccatctcc agtagaacca gtagatggat aagtccgtcc accagttgtt aagataatgg
    11821 caggagcatg gaactcttcg aattccgtgc gtataccgta aattttatgt tctttgtgga
    11881 tcaatttctc tactcgagta gagaatagaa gcgtcacatc tagttctttc agacgattga
    11941 gcaatgcttc gataatcgtt tttgatttat ttgttacagg aaacatccgt ccatgatcct
    12001 cttcttttaa atgtacgcct tgtgattcaa agaagttcat gatatcgaaa ttattccatt
    12061 gcgcaaacgt actatataaa aactttccat ttccaggaat atgtgcaatc aaatcatcaa
    12121 caggacgatt gttcgtaaca ttgcaccgac caccacctgt catcagtagt ttttttcctg
    12181 cttttttgtt tttttcgatc aagagtacgc gtgcgccttg ttcagctgca ctgatcgctg
    12241 ccatcatccc gcttgttcca gcgccgacta cgatcacatc atacagtttt tccattccct
    12301 cacctcaagg aaagtgtagc atatctgaag aaagaaaaca gaaaaaaatg ttttgagcca
    12361 aaagagaaaa tgagctaaaa tgagggaaga taagcaaagg agcgtggaac gatgacaaac
    12421 gcaacagaat atgttcaagc aattcaagaa aagctacatc aaaaggatca agggcaagaa
    12481 gaatttttac aagcaatcga tgaattcatg cccacggtta tgtctttttt ggacactcat
    12541 cccgaatata tcgaaaagaa tatcttagaa cttttaacgg aaccagaaag agttattcaa
    12601 tttcgagtgc cttggcaaga tgatgaagga aactggcgag taaatagagg gtaccgtatc
    12661 caatacaact cagctatcgg cccttataaa ggtggattgc gcttccatcc tagtgtcaat
    12721 ctaagtatct tgaaattttt ggcttttgaa cagattttca agaatagttt aaccggtctg
    12781 ccaatcggtg gaggaaaagg cggaagtgac ttcgatccta aaggaaaatc tgataatgag
    12841 atcatgcgtt tttgtcaaag tttcatgctg gaattgtcaa aacatatcgg cccatcgatt
    12901 gatgttcctg cgggagatat cggtgtagga gctagagaaa tcggctattt gttcggcgaa
    12961 tataaacgat tgaaaaaata tgatactggt gtgttgacag gtaaaccttt ggatttttgg
    13021 ggaagtaaga tacgtacgga agctactggt tatggattag tgtattatgt caaacatcta
    13081 ttgaacgaag aaaaagattc atttaatcaa aaaacagttt ttgtttccgg aagcgggaat
    13141 gtagccattt atgcaatcga aaaagtgcaa gagctaggcg ggaaagttgt tacatgttca
    13201 gattctagcg ggtacatcta tgatccagaa ggaatagatg tgaaactatt gaaagaagtc
    13261 aaagaaatca atagacaacg tttgacggaa tacgcaaacc aacgtccttc tgctatttat
    13321 catgctggag aatctgtttg gacattgaaa gaaaaagcgg atatcgcttt gccatgtgct
    13381 actcaaaatg aaatagacga aagcttggcc gaaatcttag tagaaaatgg gatcaaaatc
    13441 gtagcagaag gcgctaatat gccatgtaca gtaaaagctg tttctgttct tcatgaagca
    13501 ggcgtgtggt attgtccagg aaaagctgct aatgctggag gagtagcagt atctgcttta
    13561 gaaatgagtc agaacgtcca gcgattgact tgggaaagag agcaagtgga tgagcagctg
    13621 gatcaaatca tggaaacgat ttaccatacg tgtcgccaaa cagcagccga gtacggcgac
    13681 gaaaaaaatc tgcttcttgg agcaaatgtt gctggatttg aaaaagttgc caaagcaatg
    13741 gcagcagaag gtttagtttg aaaaatgaaa ctttcttgga aatattgtca gcattttgtt
    13801 tatttgcttg aaaaataata aaaaaaaacg taaagtatta cctgtagagt aaacctataa
    13861 ggaggagaac aaatggcaca cattcatttt gactattcaa aagtagcacc gtttgtcaac
    13921 gaacaagagt tagggtacat gcaaagccaa gtaacagcag cccacaacga attacgggaa
    13981 ggtactggcg caggaagcga cttccgcggc tggatcgatt taccaacgaa ctatgacaaa
    14041 gaagaatttg cacgtatcaa agaagcagct aaaaaaatcc aatctgattc tgaagtatta
    14101 gttgttatcg gtatcggtgg ttcttattta ggcgctcgtg cagcgatcga cttcttgaat
    14161 cacacattct tcaatttatt agatagcaac acaagaaaag caccacaaat cttctttgcc
    14221 ggaaattcaa tcagctcaac atatattgct gacttgatcg aagtaatcgg tgatcgcgac
    14281 ttttcagtaa acgttatttc aaaatctgga acaactactg aaccagcgat tgcgttccgt
    14341 gtattcaaag agcttcttgt taagaaatat ggacaagaag aagcaaacaa acgtatctac
    14401 gctacaacag ataaagcaaa aggtgcagtt aaagtagaag cagatgcaga aggttgggaa
    14461 actttcgtga ttcctgatga catcggcgga cgtttctctg tattaactgc tgttggtttg
    14521 ttaccaatcg ctgttagtgg tgcagatatc gatgcattga tgcaaggtgc cgctgatgca
    14581 agcaaagcat actcaagcga caaactagaa gaaaacgaag cttaccaata cgcagcaatg
    14641 cgcaacattc tttaccgtaa aggcaaagta actgagttgt tgatcaacta tgaaccagga
    14701 atgcaatact tctcagaatg gtggaaacaa ttgtatggtg aatctgaagg aaaagaccaa
    14761 aaaggcatct atccttcaag cgcaaacttc tcaactgatt tgcactcttt aggacaattc
    14821 atccaagaag gacgtcgcaa tatttttgaa acagttgtga aggttgaaaa acctcgtaaa
    14881 tcaatcacaa ttcctgaaca agcagaagat ttagacggtc taggctactt gcaaggaaaa
    14941 gaagtggact tcgtaaatac aaaagcattt gaaggaacat tgcttgctca tacagacggt
    15001 gacgtgccta acttgctagt caaaattcca gaaatggatg cttatacatt gggttataca
    15061 atgtacttct ttgaaattgc tgtaggtatt tcaggttact tgaatggaat caacccattc
    15121 gaccaaccag gtgtagaagc ttacaagaaa aacatgttcg cacttctagg caaaccaggc
    15181 tttgaagatc ttgctaaaga attgaacgaa cgcctgtaag ataagggttt ttcgctagat
    15241 ttaaataatc agtgatagaa acatgttcgc tttaaaatga aaactggtac ccatttaggt
    15301 actcaaacat actgcatcgt ttattcagaa taaggggctg tgacaagacg tttgtcacag
    15361 tcccttgttt gtatagaaat cgattgattg ccttgctctt tagtttgttt taggacttta
    15421 agaacagtga ggctgacttc gaaggttaat tctgtttttt tgttttctag aatcagtaag
    15481 caaaaaagca ctcacttcga gtgctttttt gcgatatatt cttagcttaa gataggccta
    15541 atttttcttt tacagatgag ggtaccttat cgctggtaat tacttttttc tctatgatcc
    15601 gcttttcgct tgctttcaac tgcaagatcg ttccttcggg gtaagcagaa ccattggcag
    15661 agtcaccaga agtaatgaca tcgaaatcta actgtctttt ttcaccgttt tcagcataag
    15721 catctacgtt gtatttaaaa cctcttccaa ttacttcccc attatctgct ttgatatcag
    15781 tttctgcagg cattggagct ttgactaccg cataataatc tttacctaca taagtagact
    15841 gatagtagtc ccaacctttc catcctataa aagcaatcaa tatgataacg atcaacccta
    15901 aaattttttt catgaaagat ctcctttttt attttta
//
LOCUS       DAXLPY010000055        15718 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.055, whole genome shotgun sequence.
ACCESSION   DAXLPY010000055 DAXLPY010000000
VERSION     DAXLPY010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.055"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            3..209
                     /locus_tag="ACF3UF_001978"
     CDS             3..209
                     /locus_tag="ACF3UF_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFD3672071.1"
                     /translation="MLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIRMAIVLFSI
                     FLGYTASNFFLEVIALCRNLFVSL"
     gene            306..1607
                     /gene="murA"
                     /locus_tag="ACF3UF_001979"
     CDS             306..1607
                     /gene="murA"
                     /locus_tag="ACF3UF_001979"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFD3672072.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1620..1796
                     /locus_tag="ACF3UF_001980"
     CDS             1620..1796
                     /locus_tag="ACF3UF_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFD3672073.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            1931..2227
                     /gene="yidD"
                     /locus_tag="ACF3UF_001981"
     CDS             1931..2227
                     /gene="yidD"
                     /locus_tag="ACF3UF_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFD3672074.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2412..2879
                     /locus_tag="ACF3UF_001982"
     CDS             2412..2879
                     /locus_tag="ACF3UF_001982"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3672075.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            2964..3848
                     /locus_tag="ACF3UF_001983"
     CDS             2964..3848
                     /locus_tag="ACF3UF_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3672076.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            3962..4198
                     /locus_tag="ACF3UF_001984"
     CDS             3962..4198
                     /locus_tag="ACF3UF_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFD3672077.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4286..4366
                     /locus_tag="ACF3UF_001985"
     tRNA            4286..4366
                     /locus_tag="ACF3UF_001985"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4320..4322,aa:Tyr,seq:gta)
     gene            4373..4444
                     /locus_tag="ACF3UF_001986"
     tRNA            4373..4444
                     /locus_tag="ACF3UF_001986"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4405..4407,aa:Gln,seq:ttg)
     gene            4569..4739
                     /locus_tag="ACF3UF_001987"
     CDS             4569..4739
                     /locus_tag="ACF3UF_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672078.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            4959..5666
                     /locus_tag="ACF3UF_001988"
     CDS             4959..5666
                     /locus_tag="ACF3UF_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3672079.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5725..6369)
                     /locus_tag="ACF3UF_001989"
     CDS             complement(5725..6369)
                     /locus_tag="ACF3UF_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFD3672080.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6495..6782
                     /locus_tag="ACF3UF_001990"
     CDS             6495..6782
                     /locus_tag="ACF3UF_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672081.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            6890..7210
                     /locus_tag="ACF3UF_001991"
     CDS             6890..7210
                     /locus_tag="ACF3UF_001991"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3672082.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7291..8605
                     /locus_tag="ACF3UF_001992"
                     /pseudo
     CDS             7291..8605
                     /locus_tag="ACF3UF_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            8602..9321
                     /locus_tag="ACF3UF_001993"
     CDS             8602..9321
                     /locus_tag="ACF3UF_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFD3672083.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9449..10000
                     /gene="raiA"
                     /locus_tag="ACF3UF_001994"
     CDS             9449..10000
                     /gene="raiA"
                     /locus_tag="ACF3UF_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFD3672084.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10222..12756
                     /gene="secA"
                     /locus_tag="ACF3UF_001995"
     CDS             10222..12756
                     /gene="secA"
                     /locus_tag="ACF3UF_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFD3672085.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            12882..13983
                     /gene="prfB"
                     /locus_tag="ACF3UF_001996"
     CDS             join(12882..12953,12955..13983)
                     /gene="prfB"
                     /locus_tag="ACF3UF_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFD3672086.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14088..14774
                     /gene="ftsE"
                     /locus_tag="ACF3UF_001997"
     CDS             14088..14774
                     /gene="ftsE"
                     /locus_tag="ACF3UF_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFD3672087.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14767..15651
                     /gene="ftsX"
                     /locus_tag="ACF3UF_001998"
     CDS             14767..15651
                     /gene="ftsX"
                     /locus_tag="ACF3UF_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFD3672088.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
BASE COUNT         5292 a         2666 c         3426 g         4334 t
ORIGIN      
        1 cggtgcttcg aatcgtgagt catttggcgt ttatctactt agccttctgg tctttacgtt
       61 cgttacgcat tgaaactttt ttcagaccaa tgcataatac gcaaattaga atggcaatcg
      121 tacttttttc aattttttta gggtacactg caagtaattt tttcttagaa gttatcgctt
      181 tatgccgaaa tcttttcgtt agcctgtaaa ttttaaaaaa aggtactatt ttaaaagcaa
      241 ggatgttata atagaaaaga ttttgagtaa gtgtatgctc attggaattt tttggaggga
      301 acaacatgga agagatcatc gtaagaggtg gcaatcaatt aaatggaaca gtaagaattg
      361 aaggagctaa aaatgctgtt ttgcctattt tagctgctag tttgttagca gaagaaggta
      421 ttacgacatt agacaacgtt ccgattcttt ctgatgtctt cactatgaat caagtgattc
      481 gtcacttaaa cgtagatgta gattttgatg aacaaaagaa tcaagtaaca atcgacgctt
      541 caagacaatt agaaatcgaa gcgccttatg agtatgttag tcaaatgcgt gcttcaatcg
      601 ttgtgatggg tccgctactt gccagaaatg gacatgcaaa agtagctatg cctggtggat
      661 gtgcgattgg taaacgacca atcgatttgc atttaaaagg atttcaagct ttaggagcaa
      721 aaattattca aaaaaacggc tatatcgaag caattgcgga tgaattgatc ggtaacacga
      781 tttatttaga tttccctagt gtaggtgcta ctcaaaatat catgatggct gccgtaaaag
      841 caaaaggaac aaccatcatt gaaaacgtag ctcgcgaacc agaaatcgtt gatttagcaa
      901 acattttgaa taaaatgggc gctcaagtct atggagctgg tactgaaaca atgcgtattg
      961 aaggcgtgga tcatttacat gcagtcaacc actcaatcgt acaagatcgt atcgaagcag
     1021 gtacctttat ggttgctgct gcaatgacac aaggcaatgt gctgattgca gatgctatct
     1081 ctgaacataa ccgcccattg atttctaaat tgatcgaaat gggtgcagaa atcattgaag
     1141 aagaaggcgg agtccgtgtc atcggaccaa aacatatctt acctacagat gtaaaaacga
     1201 tgcctcatcc tggtttccct acagatatgc aagctcaaat gacagctatc caattagttg
     1261 cagaaggtac aagtgtagtg actgaaacag tgtttgaaaa tcgtttccaa catttagaag
     1321 agatgcgccg tatgaacgct catgtcaaaa tcgacggaaa tgtagcaatc atggatggaa
     1381 accatgaatt gcaaggtgca gaagtatatg caacagactt gcgggcagca gcagcattag
     1441 ttttagctgg cttgaaagca aatggaatca cacgtgtgcg taacttgaat tatctagacc
     1501 gtggatatta taatttccat atcaaactac agcaattagg tgcagacgtt gaacgtgtag
     1561 acatggatca aacttctgct gaaaaaacag cacaaacgat tgcttaagga agtggctgaa
     1621 tgagtaacca acgatatatc ttattaactt tgataaagat tttaatggtg atcttattgc
     1681 ttatccttct ttttgtggcc ggaacgatga tcggatatgg tgtcatcggt ggcggcaatc
     1741 catttaaagt atttcagcca agtttgtgga ttcatattcg agactttttt cattgataaa
     1801 taagaatcac agtggttcta gtcgatatga agtgagccat gaagcagaac atgataaaag
     1861 aaaacagaag ggaacgttga cgttagtcgc gatccctttt tttagtaaaa gaaaagaagg
     1921 aatctaattg atgaagaaga tattgattta tttagttaga ggatatcagc gctttatttc
     1981 gcctgcattt ccacctagct gccgttatta cccaacctgt tccaattata tgataaaagc
     2041 aattcaaacc catggcgcgc taaaagggac ggtaatgggg actgcacgga tcttacgctg
     2101 tcatcctttt gtcaaaggcg gtatcgatta tgtaccattg acattccgat taacgcgaaa
     2161 taagaaagat aaaaaagaac cagattataa aaaggttgtg aaaaatacgg gtagcactga
     2221 gcgataaaga aacaatttgg aaaatagctt cttatatttt gcaaaattgt gagttattgc
     2281 cgaagtgttg gattttgaac accgtcaaaa aaaaggttgt gaaaaatacg gctagcactg
     2341 agcgataaag aaaaagagga aatttattgt caaagtaaca actccgcaac tacttatatg
     2401 ggggacaaaa aatgatcgaa gaactaaaca agaaagattt accatggtcc ttgttattag
     2461 atgcagatcc tgataaagaa aaagttcaag tatatgtttc cagagggagt ggctggatat
     2521 ggaaagaaaa agaaaaaaca ataggtgtac tgatctatgt ggcaagggaa aaagaatacg
     2581 aaatcgtcaa tgtagcagta accccaacgt atcaaggaaa ggggattggc ggaaaattac
     2641 ttgagacagc ttttcagaag ctttcacaac tcgcttccag tcaaactcag atcatcatac
     2701 gaaccggcag tactagcagt gcggcgttac atctctatca aaaaatgggc tatgtggaga
     2761 ttggtcgagt caaagactat tttatccatc attactctga gcccattttt gaaaatggag
     2821 atcaattaag ggatcaagtg attttagcaa ttcacttacc taaaaatagc tttaactaat
     2881 aaaatttcaa ttcaagaaaa tgctttcaaa tgctaaatag atacattaca atagctttag
     2941 caaacaaaaa ggagaatatt tttatgggaa tattagtttt tgattttggt ggatcggctg
     3001 tcaaatatgg ttgttgggat ggcaaagaga ttaaaggtaa gggacaattt gcaacgcctg
     3061 aatcttggga agaaatgaaa gcgcaattat ttcaagttta taaaaaaata ctcgtttctt
     3121 ttgaagtcga aggaattgga atcagctctc ctggagtagt gaataatgag aaacaggtga
     3181 ttgagggaat cagtgcgatt ccttatattc atggatttaa tattttccga gatttggaaa
     3241 ctctgtttca acttccagta acgattgaaa atgacgccaa ctgtgccgga atggctgaat
     3301 tttatgaagg tgctgcccgc gattatcaag atgttgcttt tgttgtggca ggaactggga
     3361 ttggcggggc gttgttcacg aaaggacaaa tcaataaagg ggcacatctt tacggtggag
     3421 aatttgggtt gatgttctta aatggcgata agacattcag taaacttggt acagcggtac
     3481 agatggcttg gcgttattgt gaacgcaaag gtctcgataa aaatgcttat accggaaaag
     3541 atgtctttga attagcagaa actggagatg caatagcaaa agaagaagtt gagagttttt
     3601 atacgtatct tacaaaggga ttattcagta ttcaattttc gtttgatcca gaagtgatcg
     3661 tattaggcgg cggggtttct gcaaaagaag ggctcattga tgagatcaaa agccgaatga
     3721 agaagctgac agaacaattc gatctgcatg atttcgaacc gcagatttta ttatgtgaat
     3781 acagaaacga tgctaatctt gtaggtgcag cagcaaacta tctcgctgta cgtcaagggg
     3841 agaattaaga gctttagaga aggtgcagct tgcataaaag aagtgaatga aatgaatagg
     3901 agatttttac ctaaggaatg ttttatttgc tgcagtatga taaaatatct gagaggtgaa
     3961 aatgatgtca aaaaaaaata aagatattga agtgcgtata gaagaagtga aaaaagatat
     4021 caaaggtaag aattatgaag tcactcagtt atttataggg aaaaaaatga ttggtgagat
     4081 cttagcctat ggaccaaaag aatatgaaat tttctttggt gaagaagatt ttggaaaaga
     4141 aaaaagtctt gaaaatgcga tagaaacagt gattcgacac tggaatctgc acgaataaaa
     4201 aaatatcaaa aaaactttca ataaagggtt gcaaaaatct ggaaaattag gtattataac
     4261 taagtcaggt tgatacaaac ctttcggagg agtagcgaag tggctaaacg cgacggactg
     4321 taaatccgtt ccttagggtt cagtggttcg aatccactct cctccatttc attggggtat
     4381 agccaagcgg taaggcaagg gactttgact ccctcatgcg ttggttcgaa tccagctacc
     4441 ccagtatacc acaatcgtaa gctctcgtta gttcgagagc tctttttttt gctttgctac
     4501 cttgttcctt gaagattctg ctgatttaag atagagttaa gttaactaca agaattggag
     4561 ggatccacat gaaatggaaa gaaaaagtag acgaagcagc tgaaaagtta tatgatttgg
     4621 tcaaatcaga aaaatacaat attgaagtga atattccgaa aaaaggcgga aaagcggtcc
     4681 gggtaaaatc aaaacgccca acgaatcata caaaaaaatg gatggctaaa aaccgctaat
     4741 aataacaaaa gatccataag tcggcatttt catcgatttt agggtctttt gttattttct
     4801 aggttggaca tatctaaaaa attgtttctg acaataggag taggaagaac gatgtgtgtc
     4861 taaatcctct gttgatggat agaaaccttt atctttttca gttgtgaatc aggtatatac
     4921 cagttataat agaagaaacg aaaggacggg tgtacgttat gtcgaatcaa ttacctgtat
     4981 atatacagat tcatgaccaa ttaaaaaatg aaatcgaaca aggtatatgg aaagtcggag
     5041 accgtcttcc ttcagaaaga gaattagcag tgaaattcaa tgtcagccgt atgacgttga
     5101 gacaagcaat tcaaaacttg gcagatgaag gaatcttaga aagaaagatc ggttcgggta
     5161 catatgttgc acgagaaaaa gtacaagaaa aaatgtctgg tgcaacaagt tttacagaaa
     5221 ttatggaatc acaaaatcga gtaccgtcta gtcggacaat ctcttatttc ttgacttcgc
     5281 caagctcaag tgaaatggaa aaactaaact tgagtaaaga tgacacgatc ttgcgaatgg
     5341 aacgtattcg tttcgcagat gatgtcccta tttgttttga agttgccagt gtgccacaaa
     5401 agctgatcga tggctacagc aaagcagaga ttactgaatc gttgtatcgc acgctagaag
     5461 aaaaaggcgg gaaaaagatc ggtccagcga atcaaacgat tactgctgtg ttggcttctg
     5521 agaaaattgc tgactattta gaggtaaaac gaggagatgc agttcttcgt ttgcgccaga
     5581 tttcttattt tgaagacggt acgccgtttg agtatgtgcg tacgcaatac gtaggaaatc
     5641 gttttgagtt ttatttggaa aaataaaaaa caggtgatcc ctgattccgt attagaaata
     5701 aaagagaatc agaatcacct gtttttatat atgatcagtt accagttgct cgtgataaga
     5761 aacaggaccc tcttcaaatt ggacttgtcc gttcagcagc tcaatgatgg attctttaaa
     5821 gtggtcagca cttttttcat ctacagcaca gatgacgcta acttgatcag tatattggat
     5881 ttcttttata aaaaaatgtt ggagttcaag ataattctgt aattttccta gttgcggata
     5941 cgtgatcatc acagagatct cctgttgcaa ggtaccttct acgattccaa tgtcagacaa
     6001 tgcttgagag accgcatgag tgtatgctcg tattaatccg cctgtgccga gtttcgttcc
     6061 tccaaaatat cgagtgacta ctgcagctac attgatcagt tgattttttt tgaggacttc
     6121 caacatcggt atgcccgccg ttccacttgg ttctccatca tcgctgcttc gctggatttc
     6181 atttttttct ccaatgatga aggcgctgca gttatggttc gctttccaat gttctttttt
     6241 tatttcttga atgaaacttt ttgcttcgtc ctctgattct attcgtctaa gagaacagat
     6301 aaagcgtgat tttttgatct cgatctcact ttgtccattt tcttttattg tacgatagcg
     6361 ctcgatcatc ttgtcacctc ttttttcatt ttctttattc agtataaata aagttctagg
     6421 ttgtttcaac actgtaacgg ttgcgcaatt gctgtagtat gcgataataa agacaaaggc
     6481 aggtggatct ggggatgcag gaacgaatga aaaagtacga tgcaattacg cattatttga
     6541 agaacaatgg cggctctcaa gtaacgttga cctttaccca atttgacgaa ctgctgtttc
     6601 ccagtaacgg acttcccaaa acagcaaggg aaagtacaga ttggtgggca aatgattata
     6661 aacaccctga aaaaggtgcc tatggctgga taaatgcagg ctatgaagta gttgtcatca
     6721 atttggacaa agaatatgtc gtgttcaata aattagtgaa atctagttgg ctatttgatt
     6781 aaataaaccg cgtttagaaa acgttgacaa atttctttct ttttatataa tagagtaaca
     6841 gacgcgaaga aaacgtttgc gtagtttgtt ttaaaaagga gagaaaagta tggctaaaaa
     6901 aacaatcatg cttgtatgtt cggctggtat gagcacaagt ttactagtaa caaaaatgca
     6961 aaaagctgct gaagcaaaag gaatcgactc tgatattttc gctgtgtccg cttctgacgc
     7021 agataacaat cttgcaaata aagacgtgga tgtgttgtta ttaggcccac aagttcgctt
     7081 tatgaaagct gattttgaga aacgtctgga accaaaaggc attcctttag atgtcatcaa
     7141 tatggctgat tatggtatga tgaatggcga aaaagtgtta gatcaagcaa tcacgctcat
     7201 aggtgaataa atagaacagt ataactatcg aacaagcgat ccaaaaaata gatcgcttgt
     7261 tttttcgtat atttttttag ggcgaataat atgaatcatt tttggggtag aaggcttctg
     7321 acgagagata ttaaagcaat agactgtgag gaggtaaatt taccaaatta tgagaagatc
     7381 gcagcagtgg aacgtttgag caactggatt ctttgtcatc gctgtggaat gagaacgtcc
     7441 gtcattgatg gacagcttgc agattacggt tatttttgta cacattgtct atatttaggg
     7501 cgatgcgaca ctcaacaaga tttatatttg tttgatcagc ctgaagcaaa acctcgagaa
     7561 gtcgtctttt ttttggacag gacagcttac tgaaaaacaa acggaaatct caaagagaat
     7621 actttgccat tcagaaaaaa gacatcatct tatttgggct gtaacaggtg cagggaaaac
     7681 agagatgctt tatcctattt tagtggaaac tttaaaagct ggaggaagag tagcgatttg
     7741 tacaccgcga gtcgatgttt gtaatgaatt gtttttacgc tatcgttatg tttttccaga
     7801 agaaaaaatc acgttgctcc atgggaatac agcaacggct tataccttta cttcttttgt
     7861 tatctgtacg attcatcagc tataccgttt ttatcggtcc tttgatttaa tagtgatcga
     7921 tgagatcgat gcgtttcctt ataacgggga tgcaggatta gctcatgctg tgcaaacagc
     7981 gattaaacca gacggacgat tcatctactt aagtgccaca cctgataaaa agttactaaa
     8041 ggagatcaag cagacgtttg acatccacaa acttgcttta cgctttcatc ggcgtttgct
     8101 tcctgaaccc gtcttggttt tcatgaataa ttggcgacaa aaatgcaaga acaagaagaa
     8161 gataaaatct ttggtgcgga tcattcatca attaattaaa gaaaaccata tccttttatt
     8221 ttgtccaagt atcacgatga tgcatcgttt gaaagccaca cttcaagagg ctcttccgag
     8281 atatgagatc acagatgttt cttcaagaga caatcagcgg gcggaaaaag tccagaaaat
     8341 gcgagaagca aaatatgaca tactgttaac cacgatgatc cttgaacgtg gagtcacatt
     8401 tgaaagaata tccgttatcg ttttaggagc ggatcatccg gtttttacta aatcttcttt
     8461 ggtacaaatc gcaggaagag ccgatcgtaa agggccttat acgaacagtc aagtatattt
     8521 tttctatgaa gaaaaaactg cagctattcg aaaagcttgt caggaaatca aagaaatgaa
     8581 tgaagaaggg aagaagatac tgtgaggtgc agttgctgca gtaaagatat cgtccaaaat
     8641 ttaacattca gcgagattat tggtgtttcg aaatacagat tacctcagac ttgttcagtt
     8701 tgtcgcgcac aatttcattt attggaaaca agaggctgtt ctggctgtca aaaaccaatc
     8761 catttcaatc tagagagtac gaaaaagaaa gtaaattcta tccccgttta ctgcagtgac
     8821 tgtcaagaat ggaagaagaa atatccgacc tatgattttc agcaccgtgc cttttttgtg
     8881 tacgatgaaa atatgaaggc ctggctcaat caatacaagt ttatgggaga tatccgacta
     8941 gcaggcacct ttgcatataa atggacgcag ataaaaaaag aatacccgac atacatctat
     9001 tgtccaatac ctttatctga aaaaaggcga acagaaagag gattcaatca agtaagcgag
     9061 atgttgaaag cagcaagaat tccttttcag atgctactca aaagagagaa gcatctgctg
     9121 gctcaagcaa aaaacacgcg aaaggaaaga ttggagatgc ctcaaccttt tgaacttgca
     9181 gtcacctttt ctaagataca aaataaaaaa atattgatta ttgatgatgt ctatacaaca
     9241 ggacagactc ttttccacgc agcagattgt ttgcagatcg cacagccgaa aatcatccga
     9301 actatttctt tggcgagatg aattagatgt ggaaatttga tagcgattta atttgcaaat
     9361 aacctagagt tcgatataat agaattaaga agagggaaag agtggtcctt ctccttcttg
     9421 attgtggtag acgaaagggg taatttttat gtttagatat aatgtacgcg gcgaaaatat
     9481 cgaagtaact gaagcgattc gcgactacgt tgagaaaaaa gtaggcaaac tagaacgcta
     9541 tttcagtgac gcacccgatg caacggcgca tgtgaactta aaagtttata cagaaaaaac
     9601 agcaaaagtg gaagtaacga tcccattacc ttatcttgta ttacgtgccg aagaaacttc
     9661 tccagattta tacgcaagta tcgatttggt tgttgacaaa ttggaacgcc aaatccgcaa
     9721 attcaaaaca aaaattaatc gtaaatcccg tgaaacgggc atgaatactg caaatgctgc
     9781 tgctttattc aatgaagagg acgaaaacga aaatgattct gaattagata tcgtacgtac
     9841 gaaacgcctt tcattgaaac caatggatag tgaagaagca gtcttgcaaa tgaacatgct
     9901 gggacataac ttctttattt ttgaagatgc agaaacaaat ggtacaagta tcgtttaccg
     9961 ccgtaaagat ggaaaatacg gactgattga aacagactga tcagccttac ttaaataaca
    10021 acgaaaactt gcagcagcta ctgacagctg ccgcaagttt ttttgagttt cctcctcttt
    10081 tagatgaaat atgaataaat tatgaagttc ttactttaat acgcttaaga tatttcaatt
    10141 atctataact aatgataaaa tgaaaagtaa agtctacata gtctggataa tacacagaag
    10201 gaaaaggaga ttacacaacg catggccaat ttgattcgtt cacttatcga aaacgataag
    10261 aaagaactaa aacgtttaga tagcattgca aaaaaagttg aagcatacgc tgaccaaatg
    10321 gcagcattaa ctgatgaaca attacaggca aaaactgctg aattcaaggg cagataccaa
    10381 aaaggagaaa cattagatca attacttccg gaagcttttg cagtcgtccg agaagcagca
    10441 aaacgtgtat taggtttata tccataccac gtacaattga tgggtggaat cgtgcttcac
    10501 gatggaaata tccctgaaat gcgtactggt gaaggtaaaa ccttgaccgc aacgatgcca
    10561 gtatatctaa atgctctgac tggcgaaggg gtacacgtag ttaccgtcaa tgaatattta
    10621 gcaacccgtg actcgacgga aatgggcgaa ctttataatt tcttaggatt aacagtgggg
    10681 ttgaatatca actcaaaatc ttcggatgaa aaacgcgagg cttataattg tgatatcact
    10741 tatagtacga ataatgaatt aggatttgac tacttgagag acaatatggt cgtttaccgc
    10801 catcaaatgg tacaacgtcc gctgaattat gccattgtcg atgaagttga ctcaatcttg
    10861 attgatgaag cgagaacgcc gctgatcatt tcagggcaag cagaaaaatc cacagcttta
    10921 tatacaagag cagacaactt cgtgaaacgt ttgaaagaag aagaagatta taaaatcgat
    10981 gtacaatcaa aaacaatcag tttaaccgaa gcagggatcg aaaaagcaga agaaacattc
    11041 ggtttggata acttatacga cattgaaaat actgcattga cccatcactt ggatcaagca
    11101 ttgagagcca actatatcat gcttttagat atcgattatg ttgtccaaga cggaaaagta
    11161 ctgattgttg accagttcac tggtcggatc atggatggac gccgttattc agatggactt
    11221 caccaagcaa tcgaagctaa agaaggcgta gagatcgaag acgaaacgaa aaccatggcg
    11281 acgatcactt tccagaacta tttccgtatg tacaagaaac ttgcgggaat gactggtaca
    11341 gctaaaacag aagaagaaga attcagagaa atttataaca tccaagtata ccagattccg
    11401 acaaatcgtc cggttatccg tgatgatcgt ccagatttgc tttacccaac attacaaagc
    11461 aagttccacg ctgtcgtgca agatatcaaa gatcgctacc gcaaaggtca acctgtgtta
    11521 gtcggaactg ttgcggttga aacatctgag ttattatcag atatgctgaa tcaagaacgt
    11581 attcctcatg aagtgctgaa tgcgaaaaat cactttaaag aagcagagat catcatgaat
    11641 gctggtcaaa aaggtgctgt gacgattgct accaacatgg ctggtcgggg aacagatatc
    11701 aagttaggac ttggggtaag agaacttggt ggtctagcag ttatcgggac agaacgacat
    11761 gaatctcgtc gtatcgataa ccagcttcga ggacgtgcag gacgtcaagg agaccctggt
    11821 atgtcacagt tctacttgtc attggaagat gatttgatga aacgattcgg ttcagaacga
    11881 atcaaatctt tcttagatcg gatgaagatc ggtgaggaag atgctgttat ccaaagcaag
    11941 atgctgacga aacaagtaga atctgcacaa aaacgtgtag aaggaaataa ctatgacaca
    12001 cgtaaaaacg tcttacaata cgatgatgtg atgcgtgaac aacgtgaagt aatctataaa
    12061 cagcgacaag aagtaatcat ggaagaaaaa agcttatcca agccactaat gaacatggtc
    12121 aaacggacaa tcagtcgtgt agtagatgcg catacacaat tagagaaaga aaattggaat
    12181 ttggaaagta tcatcgattt tgccggcagt actcttgtcc atgaagatag tattactctt
    12241 gcagatatcg aaggaaaaac agctcaggag atcaaagagt atctaaacga acgagcacaa
    12301 gaagtattta ataccaaagc ggctcaacta aatggtccag agcaactgtt ggaatttgaa
    12361 aaagtcgtga tcttgcgtgt tgtggactct aaatggacag accatattga tgcaatggat
    12421 caattacgtc agtcaatcgg cttacgtgct tatggacaga acaatccatt agtcgaatat
    12481 caaacagaag gctataagat gtttgaagat atggtaggcg ccatcgagta tgaagtcact
    12541 cgaatcttta tgaaagctga gatccgtcaa aacgtacagc gtgaacaggt ttctcaagga
    12601 acagcttctc actcagaaga cggagatgcc aaagaaaata gtaatactag cgcgaaaaaa
    12661 cagccaatcc atgtgaacaa ggtcggaaga aatgatcctt gtccttgtgg aagcgggaaa
    12721 aaatataaga actgtcatgg aaaaaatgca aactaatttc tgacagcagg attggtgaga
    12781 caaattcttt ttttaagaat tcgtctcacc ttctttctgt tatttgctga ttctgttaga
    12841 ctagatataa tgaaaaaagt atagtgaaag aaggaaaaaa catggaaata tccgaaattc
    12901 gaaatctcct gacagaaatg caggaaaagg tcacaagctt caggaggtct ctttgactta
    12961 gaccagctgg aagaagacat tgcggaagca gaagcaaaaa tggctgaacc tggtttttgg
    13021 gatgatagcg aagctgctca aaaagtgatc agtgaaaaca atgcaaataa agaaacttat
    13081 gatcaattcc attctcttgc tgaagaactg gaagaaatcg aattgatggt ggagatgttg
    13141 caggaagaac ctgatgcagc catgcaagaa gaagcagaaa cacgtatcaa tgcgctagat
    13201 gaaaaaatga agacatatga attatctatg ttgttagatg gtccttatga tcgaaacaac
    13261 gccatcgttg aattgcatcc aggggctggc ggaacggagt cccaagattg gggcagtatg
    13321 cttttacgta tgtatacacg ctgggcagag cagcatgggt atcaagtaga gacactagat
    13381 tatcaagcag gtgatgaagc aggaatcaag agtgtgaccc tactgatcaa aggacacaac
    13441 gcatttggtt atctgaaatc agaaaaaggt gttcatcgcc ttgtacgtat ctcgcctttt
    13501 gactcagcga aacgacgtca tacttctttt tgttcggtag atgtgatgcc agagcttgat
    13561 gaaacgatcg atatagaaat caatccagat gatttgaaaa tcgatacgta ccgagcaagt
    13621 ggtgcaggtg gtcagcacat caataaaaca gaatctgctg tacggatcac tcacttgcct
    13681 acaggaacag tagtagctag tcaggcacaa cgttcacaat tgaaaaaccg tgagcaagcg
    13741 atggggatgt taaaagctaa gctttatcaa ttagaagtgg aaaagaaaga acaagaagca
    13801 gctgcacttc gaggagaaca aaaagaaatc ggctggggtt cacagatccg ttcttatgtt
    13861 ttccatccat attctatggt aaaagaccat cggacaaacg tagagacagg aaatgtccaa
    13921 gcagttatgg acggtgacct tgatttattt attgacggct atttaaaaat gcatctacaa
    13981 taagaaccca ttgttaaatt gaaataaaat tgtaagattt tgcaagcatg ttgaaacatt
    14041 gccatgctat aatagctaaa gactgaaaaa gatatggaga gaacgccatg attgaaatga
    14101 aggatgtaat gaagaagtac tcaaatggta cgaccgctat ccgcaatctc tcaattgtca
    14161 tcgaacaagg agagtttgtc tatgtggttg gtccgtctgg agccggtaaa tctacattca
    14221 tcaaattgat gtatcgagaa gaaaaagctt caaaaggaac tttgaacgtc gcaggtcatg
    14281 atctaatagc aatcaaaaac cgcgaagttc cttatctacg cagagaaatc ggcgtggtgt
    14341 tccaagacta taaattatta ccaagaaaaa cagtatatga aaatgttgcg tacgctatgc
    14401 aagttatcgg cagaaaacct cgggatatca aaaaacgagt aatggaagtg ctggaccttg
    14461 ttggtttgaa acacaaagtt cgagtctttc ctagcgaatt atccggtggg gaacagcaac
    14521 gtgtctctat tgctcgggca atagtgaata cgcctaaagt acttatcgcg gatgaaccga
    14581 caggaaatct ggatccagaa aactcatggg aaatcatgaa attattagat cggatcaatg
    14641 cccaaggaac tactgtcgtg atggctacac ataacagtac gatcgtaaat acgattcggc
    14701 accgagtaat tgctatcgaa aacggccgca ttattcgaga tcaagcggaa ggggaatatg
    14761 gatacgatga ttagaacctt tttccgccat ttattagaaa gtatcaagag tttgaaacgt
    14821 aacggctgga tgacagttgc ttcagtcagt gcggtaacga tcacattgac tttagtcggt
    14881 gtattcatgg cagttatcat gaacgcaact aaattagctc aagatataga aggaaacgtt
    14941 gatgtctctg tattcgtaga tatcggtaca aaagacgaag agatgaaaaa gctagaaaaa
    15001 gaattgaatg acttagatca tgttaaaaaa gttgaatttt caagcaaaga acaggaattg
    15061 aaaaaaatcc aaaacgaaat gggtgattcc tggaaattgt ttgaaggtga caataacccg
    15121 ttatatgatg tgtatgtagt aagtgctact gatccttctt atacaaaaca agtagcagaa
    15181 gaagcagcag atttgaagaa tgtttctcgt tctgattacg gtggagcttc ctcagatcgg
    15241 attttccaaa tcgctggtgc agttcggaca tggggattag ttgcagcggc attgctgctg
    15301 ttcgtagcga tgtttctcat ttcgaacacg attcggatca cgattttgtc tagacagcgt
    15361 gaaattcaaa tcatgcgttt agtcggtgca aaaaatggat atattcgctg gccgtttttc
    15421 cttgaaggtg gctggatcgg tctgatcggt gcgattcttc cgattttgat catcacattt
    15481 ggttatgcat ggtttttcca attgatcaat ccatcattat tacgttccca ttattcattg
    15541 attcatccac aaaatatcgt ttggaaaatc aatcttttaa tggtcggcat tggtgtgatc
    15601 attggttcac ttggctcgat catttctatg agacgtttct tgaaattcta ataccacaat
    15661 ataaataaaa tgagaaagtt ggacagtttc gttccagctt tcttttttta ttggctag
//
LOCUS       DAXLPY010000056        14119 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.056, whole genome shotgun sequence.
ACCESSION   DAXLPY010000056 DAXLPY010000000
VERSION     DAXLPY010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.056"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(31..3684)
                     /gene="rpoC"
                     /locus_tag="ACF3UF_001999"
     CDS             complement(31..3684)
                     /gene="rpoC"
                     /locus_tag="ACF3UF_001999"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFD3672089.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(3763..7380)
                     /gene="rpoB"
                     /locus_tag="ACF3UF_002000"
     CDS             complement(3763..7380)
                     /gene="rpoB"
                     /locus_tag="ACF3UF_002000"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFD3672090.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8108..9076
                     /locus_tag="ACF3UF_002001"
     CDS             8108..9076
                     /locus_tag="ACF3UF_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3672091.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9094..9999
                     /locus_tag="ACF3UF_002002"
     CDS             9094..9999
                     /locus_tag="ACF3UF_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3672092.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            9996..10802
                     /locus_tag="ACF3UF_002003"
     CDS             9996..10802
                     /locus_tag="ACF3UF_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3672093.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10959..11927
                     /locus_tag="ACF3UF_002004"
     CDS             10959..11927
                     /locus_tag="ACF3UF_002004"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFD3672094.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12244..12768)
                     /locus_tag="ACF3UF_002005"
     CDS             complement(12244..12768)
                     /locus_tag="ACF3UF_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFD3672095.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13055..>14119
                     /gene="scm"
                     /locus_tag="ACF3UF_002006"
     CDS             13055..>14119
                     /gene="scm"
                     /locus_tag="ACF3UF_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFD3672096.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT         3997 a         3047 c         2784 g         4291 t
ORIGIN      
        1 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
       61 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
      121 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
      181 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
      241 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
      301 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
      361 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
      421 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
      481 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
      541 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
      601 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
      661 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
      721 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
      781 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
      841 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
      901 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
      961 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
     1021 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
     1081 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
     1141 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
     1201 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
     1261 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
     1321 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
     1381 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
     1441 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
     1501 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
     1561 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
     1621 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
     1681 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
     1741 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tcttttactt tgaatcgttt
     1801 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
     1861 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
     1921 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
     1981 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
     2041 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
     2101 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
     2161 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
     2221 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
     2281 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
     2341 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
     2401 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
     2461 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
     2521 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
     2581 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
     2641 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
     2701 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
     2761 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
     2821 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
     2881 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
     2941 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
     3001 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
     3061 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
     3121 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
     3181 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
     3241 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
     3301 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
     3361 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
     3421 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
     3481 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
     3541 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
     3601 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
     3661 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
     3721 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
     3781 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
     3841 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
     3901 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
     3961 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
     4021 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
     4081 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
     4141 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
     4201 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
     4261 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
     4321 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
     4381 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
     4441 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
     4501 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
     4561 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
     4621 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
     4681 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
     4741 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
     4801 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
     4861 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
     4921 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
     4981 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
     5041 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
     5101 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
     5161 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
     5221 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
     5281 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac catcatgttt
     5341 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
     5401 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
     5461 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
     5521 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
     5581 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
     5641 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
     5701 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
     5761 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
     5821 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
     5881 acgagtcaat ccgccaggtc ctaaggcgaa aagacgacgt ttgtgtgtca attcgccaag
     5941 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
     6001 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
     6061 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
     6121 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
     6181 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
     6241 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
     6301 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
     6361 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
     6421 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
     6481 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
     6541 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
     6601 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
     6661 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
     6721 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
     6781 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
     6841 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
     6901 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
     6961 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
     7021 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
     7081 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
     7141 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
     7201 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
     7261 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
     7321 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
     7381 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
     7441 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
     7501 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
     7561 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
     7621 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
     7681 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
     7741 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
     7801 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
     7861 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
     7921 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
     7981 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
     8041 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
     8101 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
     8161 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
     8221 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
     8281 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
     8341 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
     8401 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
     8461 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
     8521 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
     8581 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
     8641 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
     8701 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
     8761 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
     8821 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
     8881 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
     8941 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
     9001 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
     9061 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
     9121 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
     9181 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
     9241 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
     9301 gggagtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
     9361 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
     9421 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
     9481 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
     9541 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
     9601 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
     9661 atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa cggctttgct
     9721 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
     9781 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
     9841 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
     9901 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
     9961 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    10021 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    10081 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    10141 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    10201 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    10261 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    10321 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    10381 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    10441 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    10501 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    10561 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    10621 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    10681 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    10741 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    10801 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    10861 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    10921 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    10981 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    11041 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    11101 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    11161 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg ttgacttctg
    11221 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    11281 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    11341 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    11401 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    11461 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    11521 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    11581 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    11641 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    11701 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    11761 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    11821 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    11881 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    11941 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    12001 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    12061 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    12121 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    12181 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    12241 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    12301 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    12361 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    12421 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    12481 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    12541 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    12601 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    12661 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    12721 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    12781 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    12841 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    12901 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    12961 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    13021 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    13081 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    13141 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    13201 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    13261 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    13321 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    13381 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    13441 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    13501 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    13561 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    13621 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    13681 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    13741 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    13801 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    13861 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    13921 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    13981 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    14041 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    14101 tgatagctca gattcatca
//
LOCUS       DAXLPY010000057        14118 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.057, whole genome shotgun sequence.
ACCESSION   DAXLPY010000057 DAXLPY010000000
VERSION     DAXLPY010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.057"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..556)
                     /locus_tag="ACF3UF_002007"
     CDS             complement(<1..556)
                     /locus_tag="ACF3UF_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HFD3672097.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(572..1051)
                     /locus_tag="ACF3UF_002008"
     CDS             complement(572..1051)
                     /locus_tag="ACF3UF_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFD3672098.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1057..2081)
                     /locus_tag="ACF3UF_002009"
                     /pseudo
     CDS             complement(1057..2081)
                     /locus_tag="ACF3UF_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2098..3204)
                     /locus_tag="ACF3UF_002010"
     CDS             complement(2098..3204)
                     /locus_tag="ACF3UF_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3672099.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACF3UF_002011"
                     /gene_synonym="adhC"
     CDS             complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACF3UF_002011"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFD3672100.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACF3UF_002012"
     CDS             complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACF3UF_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFD3672101.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACF3UF_002013"
     CDS             complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACF3UF_002013"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFD3672102.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8175..8873
                     /locus_tag="ACF3UF_002014"
     CDS             8175..8873
                     /locus_tag="ACF3UF_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFD3672103.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9041..11680)
                     /locus_tag="ACF3UF_002015"
     CDS             complement(9041..11680)
                     /locus_tag="ACF3UF_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3672104.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACF3UF_002016"
     CDS             complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACF3UF_002016"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFD3672105.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13523..>14118
                     /locus_tag="ACF3UF_002017"
     CDS             13523..>14118
                     /locus_tag="ACF3UF_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3672106.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         3959 a         3096 c         2543 g         4520 t
ORIGIN      
        1 aagcgcctac gagataacct cccataaaca aagcagagat cgaagcacca ccagcaacaa
       61 gtgaatacat gataaaagca gtacttggag gaatgaccat acctgtcgga gctgacgcga
      121 tattgaccgc tgtcgcaaac ttccggtcat atccttcttc cacttgctga gggatcaaca
      181 ctccaccaat cgcggtagaa gcggcaatgg ccgagctaga gatggaacca aataaagcat
      241 tccctaacac attcgtatga gccaaagccc ccggcacgcg cccgacgaac aacatcgcaa
      301 aatccactag tttcttagct atccctccat tattcatgat aatgcccgag agaacgaaaa
      361 acggaatagc gatcagcgaa aaactattga tacttcccac cattttttga gctgaactaa
      421 aagcagaaac atcaaacggt ataactaaca ataaagtcat catcgatgag aatgcaatac
      481 ttatagcaat cggcatccct aatacaagca acacaacaaa tacaaaaaat aacactaatc
      541 cggcttctat tgccatttta ttcctccatt tttatatttt ttcttgaatt gctggcttgt
      601 tgcttaatgt atcgattaga ttgatcaggc tatagataat gatgagtacc cccgatacag
      661 gtactgacag ataaacatat cccataggaa tacttaaaga aggcgagatc tgccccattg
      721 tcaatgtgac agcattccat ccgccataca ccatgatcat cgcagcaaat accagaaata
      781 aactttgaac aacaacttct aaaattttac tttttttgcc agttaatttt tcacttaaaa
      841 ccgttacggc taaacgtgct ttttgtccca caacatacgc ggaagacaac atggcaaacc
      901 agacaagacc gaatcgaaca agctcttccg tgaccgtatt tggatttcct aaaaccgttc
      961 tggaaaatac ttgccataaa acaacagcga ccatcccaac aagcaaaaca gctcccagga
     1021 tctctaatac cttgtttaaa atcattttca ttacagctac gctccttgct cttggatctt
     1081 ttgataaagg tctttgtagg taggatcgtt tttgaatata tcatgaagtg gggcaactgc
     1141 ctctcgaaac ggtgtattat ctacatcatt gaattggact ccatgttctt cttgtgctaa
     1201 agctttttct tcttcaattg cttttgcaaa agcttcaatt tcaaaaaccg ttgattcttt
     1261 cgctgcttct tcaatggctt tttcctgttc atcagttagc tgttctttga tggcatcatt
     1321 catgatgatg atatctggca cacgtgtatg ctcatcatag gaatagtatt tagctacccc
     1381 gccatgtcca gctgtataca agacaaattc attgttttct gatccgttga tcaaattgga
     1441 ttgaagagac gtgtacactt catcacttcc cataggtacg ggcgaaccgc ctaaaagctc
     1501 taccattttg atagcggttt cgctttgcat cacacggatc ttctttccct tcaaatcttc
     1561 cggcgtatgg atcggaccgt ctaccatata aaagctgcgc tgaccagaat cataataggt
     1621 caatccggta aatcctaaat ttttggtcga ttggtagatt ggctccatta tttcttcatt
     1681 atccatcacc ttaaagaaat gttcttcatc attgaataga taaggaacgg aaaaaatcga
     1741 ataatcttta gagaaacttt ccaacgctga ggcacttact tttgtgaaat ctactgctcc
     1801 tgactgtgtc aattcgatca gttcacgttc tccacccagt tgtccatctg ggaaatactg
     1861 gatctgtacg gaaccatctg ttttttcttt tactaaacgc ccaaattcat tcattgcatc
     1921 aattactggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacgtctgca
     1981 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
     2041 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
     2101 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
     2161 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
     2221 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
     2281 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
     2341 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
     2401 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
     2461 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
     2521 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
     2581 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
     2641 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
     2701 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
     2761 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
     2821 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
     2881 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
     2941 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
     3001 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
     3061 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
     3121 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
     3181 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
     3241 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
     3301 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
     3361 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
     3421 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
     3481 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
     3541 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
     3601 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
     3661 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
     3721 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
     3781 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
     3841 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
     3901 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
     3961 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
     4021 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
     4081 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
     4141 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
     4201 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
     4261 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
     4321 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
     4381 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
     4441 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
     4501 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
     4561 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
     4621 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
     4681 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
     4741 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
     4801 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
     4861 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
     4921 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
     4981 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
     5041 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
     5101 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
     5161 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
     5221 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
     5281 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
     5341 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
     5401 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
     5461 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
     5521 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
     5581 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
     5641 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
     5701 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
     5761 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
     5821 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
     5881 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
     5941 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
     6001 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
     6061 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
     6121 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
     6181 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
     6241 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
     6301 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
     6361 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
     6421 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
     6481 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
     6541 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
     6601 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
     6661 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
     6721 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
     6781 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
     6841 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
     6901 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
     6961 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
     7021 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
     7081 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
     7141 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
     7201 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
     7261 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
     7321 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
     7381 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
     7441 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
     7501 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
     7561 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
     7621 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
     7681 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
     7741 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
     7801 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
     7861 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
     7921 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
     7981 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
     8041 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
     8101 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
     8161 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
     8221 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
     8281 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
     8341 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
     8401 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
     8461 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
     8521 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
     8581 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
     8641 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
     8701 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
     8761 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
     8821 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
     8881 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
     8941 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
     9001 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
     9061 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
     9121 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
     9181 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
     9241 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
     9301 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
     9361 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
     9421 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
     9481 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
     9541 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
     9601 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
     9661 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
     9721 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
     9781 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
     9841 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
     9901 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
     9961 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    10021 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    10081 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    10141 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    10201 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    10261 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    10321 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    10381 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    10441 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    10501 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    10561 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    10621 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    10681 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    10741 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    10801 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    10861 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    10921 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    10981 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    11041 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    11101 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    11161 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    11221 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    11281 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    11341 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    11401 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    11461 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    11521 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    11581 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    11641 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    11701 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    11761 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    11821 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    11881 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    11941 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    12001 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    12061 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    12121 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    12181 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    12241 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    12301 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    12361 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    12421 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    12481 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    12541 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    12601 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    12661 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    12721 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    12781 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    12841 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    12901 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    12961 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    13021 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    13081 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    13141 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    13201 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    13261 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    13321 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    13381 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    13441 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    13501 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    13561 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    13621 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    13681 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    13741 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    13801 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    13861 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    13921 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    13981 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    14041 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    14101 ccatgacatg gatgaagc
//
LOCUS       DAXLPY010000058        13969 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.058, whole genome shotgun sequence.
ACCESSION   DAXLPY010000058 DAXLPY010000000
VERSION     DAXLPY010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.058"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(325..2322)
                     /gene="tkt"
                     /locus_tag="ACF3UF_002018"
     CDS             complement(325..2322)
                     /gene="tkt"
                     /locus_tag="ACF3UF_002018"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFD3672107.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2424..2675)
                     /locus_tag="ACF3UF_002019"
     CDS             complement(2424..2675)
                     /locus_tag="ACF3UF_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFD3672108.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2822..3445
                     /gene="lexA"
                     /locus_tag="ACF3UF_002020"
     CDS             2822..3445
                     /gene="lexA"
                     /locus_tag="ACF3UF_002020"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFD3672109.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3624..3842
                     /locus_tag="ACF3UF_002021"
     CDS             3624..3842
                     /locus_tag="ACF3UF_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672110.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4130..4642)
                     /locus_tag="ACF3UF_002022"
     CDS             complement(4130..4642)
                     /locus_tag="ACF3UF_002022"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFD3672111.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="ACF3UF_002023"
     CDS             complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="ACF3UF_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFD3672112.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7095..7538)
                     /locus_tag="ACF3UF_002024"
     CDS             complement(7095..7538)
                     /locus_tag="ACF3UF_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFD3672113.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7539..8327)
                     /locus_tag="ACF3UF_002025"
     CDS             complement(7539..8327)
                     /locus_tag="ACF3UF_002025"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3672114.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8324..9265)
                     /gene="rnz"
                     /locus_tag="ACF3UF_002026"
     CDS             complement(8324..9265)
                     /gene="rnz"
                     /locus_tag="ACF3UF_002026"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFD3672115.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9442..10029)
                     /locus_tag="ACF3UF_002027"
     CDS             complement(9442..10029)
                     /locus_tag="ACF3UF_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFD3672116.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10250..11563)
                     /gene="obgE"
                     /locus_tag="ACF3UF_002028"
     CDS             complement(10250..11563)
                     /gene="obgE"
                     /locus_tag="ACF3UF_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFD3672117.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11851..12861
                     /gene="gap"
                     /locus_tag="ACF3UF_002029"
     CDS             11851..12861
                     /gene="gap"
                     /locus_tag="ACF3UF_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFD3672118.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12946..13881)
                     /locus_tag="ACF3UF_002030"
     CDS             complement(12946..13881)
                     /locus_tag="ACF3UF_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3672119.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3856 a         3130 c         2455 g         4528 t
ORIGIN      
        1 gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgt cgggcactgc
       61 gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa taaaaagttc
      121 tcttcttaaa acaaacttaa ttaattaaat tatactttta attctcaaga aacacaaact
      181 aatccgaaga attctttgtt ttgtcattta aatgtaacat agccgaaaac gaaaagtaat
      241 attgatttat tcttctaaca cataaagaac agctgtctcc aacttgcaga cagctgttct
      301 tatcagtcaa acaattgctt ggatctatga tagttgattg tacgtattca cgacattttc
      361 tactgtaaat ccaaattctt ctaaaatttt agtgccaggg gcagatgcac cgaaatgatc
      421 gattgtaatc gttgcgccct ctgttcctac gtagcgttcc caaccaaatg atgcagcagc
      481 ttcgatagcc acacgtttct tcactgattt aggaagtaca ctttctttat attcagaaga
      541 ttgtttttca aagaggtcaa agcttggcat agaaacaaca gaaacatctt tgcctttttc
      601 agccaattct ttttgagctt tcacagccaa atcaacttca gaacctgttg caatcaaaat
      661 accttctggt gtttctcctt gtgatggaga aagaacatac gcgccttttt tcaccatttc
      721 atctgctact tcttttgtag aaggcaatac tggaaggttt tgacgactca atacaaggat
      781 agtaggcgca tctgttgtct ccatcgctac tttccaagca gcacgtgttt catttccgtc
      841 tgccggacga atcacttgaa caccaggcat gcagcgaaca gatgctagtt gttcaatcgg
      901 ttcgtgcgtt ggtccgtctt ctccgacagc aaccgagtca tgtgttaaga cgtaaacaac
      961 aggagtatgt tggattgctg ctaaacgaac tgctggtctt agataatcga caaagacaaa
     1021 gaatgttcca ccgtagatac gagttccgcc atgaagttgg ataccattca tagccgaagc
     1081 cattgcaaat tcgcggacac cgaaccagat gttgcgtcct tcataatgtt caggagtgaa
     1141 atctttatct gcagccacca ttgtattatt ggaacctgac aagtccgctg aaccacccca
     1201 gaagcttggt atagctttcg ataattcttg gatgacttct ttacttgaaa cacggcttgc
     1261 ttgactgctt ccaacttcat aagttggcaa ttctgcatcc cagttttctg gtagtttgcc
     1321 atcaaaagca tcttcaaatt gttgtgctaa ttcaggataa gcttttttat aattggcaaa
     1381 catttcattc catgcatctt cagctttttg tccttcttct atcatcgttt gatggaagcg
     1441 ggcagctact tcttctggaa cagtgaaatc tggatactcc caaccataaa cttctttagc
     1501 catcttgatg ccatcttcac caataggagc accatgaaca gcagatgttc cttctttagg
     1561 agcaccatag ccgatgactg tttttacttc gatcaatgtt ggtttgtctg tttcagcttt
     1621 tgcttcttca atcgctttag agattgcttc taggtcattt ccgtctttca ctaagatatg
     1681 ttgccagcca tatgcttcat agcgagcacc aacgttttct gtgaaagctt ttgaagttgg
     1741 accgtctagt gaaatatcgt ttgaatcgta taaaacgatc aatttcccta gtttcatatg
     1801 acctgccatc gaacttgctt cttgagatac cccttccatc aagtctccgt caccgcatat
     1861 tgcatacgta tagtgatcca tcacattaaa gttttctttg ttatacgttg ctgcaaggtg
     1921 cgcttctgcc attgccatac cgacagccat tgcaatccct tgtcctaatg gccctgtagt
     1981 ggcttctaca ccatctgtgt gatgtacttc aggatgtcct ggtgttttag aatcccattg
     2041 acggaattgt ttcaaatcat cgattgtcac ttgatagcca gctaaatgaa gcaagctata
     2101 caacattgct gacccatgtc ctgccgaaag aacgaaacgg tcgcggtcag cccagttttt
     2161 tgatgtcgtt ggatttactt tcaggtgttt tgtccataac gcatatgcca taggtgctgc
     2221 gcccatcggc aatccaggat gtcctgagtt tgctttttgg actgcttcaa tacttaatgt
     2281 acgaattgtg ttaacgccaa gttggtcaat tttgtcaaac aaaataaccc ctcctattaa
     2341 tttaggtttt ttttaccttt atttcttaca ctttcattct ataagatgtc acacgaaaaa
     2401 gcaatctttt tcagtatttt ttactaaaag ttgtcatttc ggttgtgtaa gccttttttc
     2461 ttttggattt cttttaattt ttccggggtc acgtcattgc cctcaggatc gacgactttc
     2521 attccttcga tatgatgacg cataccggaa cgaaaagctt ccaaatactc tttgcgtaag
     2581 ttgatttgtt cttgttcttc ggcttttgag agaccatttt ccttcttttt acgtgcaagt
     2641 tcattgatcc tctctatttt ttcaggtgac agcatgctca gccctccttt tactctcctt
     2701 catattatat aaaaactgaa aaaaaaacaa ctagataaac taaataaaat acgaacattc
     2761 gtttgattta gcgcttttta tatggtacta tttatttatc aagtgaaaga aggtgtacct
     2821 tgtggcccga caaactgaat caagacaaat cgaagtctta cgatatatcc atgaacaagt
     2881 aacccaaaaa ggatacccgc cgactgtccg tgaaatcggg gaagctgttc agctttcttc
     2941 tacttctact gttcacggtc atcttgcacg gcttgaaaaa aaagggttta tccaaagaga
     3001 tccgacgaaa cctcgtgcaa tcgagttgac aaaacaaggt ttagaaaaga ttgggattcg
     3061 tccaacaact attccagtac ttggcgtcgt aacagctgga gaacccattt tagcagtaga
     3121 ggatgcttca gacttctttc caatccctcc taatctttct tccgaagaag gcagtctctt
     3181 tatgctgaca attcgtggag atagtatgat caatgctggg atcttggatg gtgacaacgt
     3241 gatcgttcgg aagcaagaaa ctgctcaaaa tggcgatatt gtcattgcaa tgactgccga
     3301 ggacgaagcg acttgcaaac gattctataa agaaaaaaac tttttccgtc tgcagcctga
     3361 aaacgacttg ctcgaaccaa tcatcttaga tcaagtatct atattaggac gagtagtagg
     3421 actttatcgt agtcatatct attaattgct actaataaaa gaaaactttt taaaaagagt
     3481 ttgagacgat ggtctcaaac tcttttttcg cccgggttct tcttctttca aatttttatc
     3541 acttccctct ttacaaaccg aacaaatatt cgtatactaa atatacgaac aattgttcgc
     3601 ataaattaac gaggtgagaa ttcatgaaat caatgagacg tcttggctta gtattaactg
     3661 ttttgttttt aggtattatt attggtaatt tcggcatacg tccagcttta cttgtgtttg
     3721 ttccgttatt tactttgtgg ttcatgttgt gggatgaaaa gaagtaccgt caatctgagc
     3781 ggcgcagaat tcatgaagat catttctatc atgagcccta ctacagatcc aggcaatcat
     3841 aataaggatt gactgctaat tattcaaaag acaagaagtt aaacttttac gggggtgtga
     3901 caaaaatcgg tcacatcctt ttttcgaata aacggtgttc taaagccagt ttttcggtat
     3961 taagtcaaat tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat
     4021 ttataaaaaa atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt
     4081 taaaatcgct tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca
     4141 ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga
     4201 tcaaaaatgc gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt
     4261 tgattgttcc tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa
     4321 tggcatcctt atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga
     4381 tggtttctcg aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat
     4441 aagcaacagg acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc
     4501 gtttttcttt tgcataattt acgatttgct tcgtagcttc ccgataagcg tcaccatctg
     4561 ccatcagtgg ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg
     4621 caatataatc ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg
     4681 gtaggaatat cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgccgctgg
     4741 tataatctgc tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg
     4801 ttctctattg taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt
     4861 tcagggatac gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct
     4921 tgagaatgga tcagtttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa
     4981 taggcctcat caggcgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa
     5041 acttctttca gatccgctaa atcatctgga caatccataa taactagaga gttcggtttt
     5101 cttttttcaa ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg
     5161 ataatctcag gcacgaattt caacgtagaa gaatcaaatg ctaaataaag gctaccttcc
     5221 gacgttcggc tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc
     5281 acagaaaaat cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa
     5341 agctttccta ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca
     5401 aaagcgaccg catcaagctg actcgatgca ttggaaagga caaatttcag atgctgttgg
     5461 tttgctccga ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa
     5521 ggattatccg taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact
     5581 tcatttggca gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga
     5641 tgatcgacta tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc
     5701 gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca
     5761 agcatttcaa aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct
     5821 tcttttaaag taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca
     5881 atgcccaaaa cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta
     5941 ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg
     6001 atctcattca atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac
     6061 gagacggcag gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa
     6121 aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc
     6181 tgaagtccta tccgttctga atgatgaatg gcattgattc ctaatgaaac aaggattcga
     6241 ttctcatcag tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat
     6301 tctacaggcg gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc
     6361 aaatctggaa atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct
     6421 ggtaaattct caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga
     6481 gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt
     6541 ccttcttcga tcttttcttg gtatacagat tggtttggtc catacccatg ctcaaatcga
     6601 tttggcagga atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt
     6661 gcactggtga tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt
     6721 acagcttctt ggattcggct gattgcttta tccatatcgt gcatcagata cggatcatgt
     6781 aattcttgtt cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt
     6841 tgccacagta acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag
     6901 gattcagaag gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca
     6961 ctcctaactt agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa
     7021 aaacagatca gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt
     7081 atgaaatatc cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt
     7141 tcttccggcg ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa
     7201 gcagcttcca actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct
     7261 tcaattttct tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt
     7321 tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc
     7381 agcgcagaac cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt
     7441 acaggaacat ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat
     7501 ccaagaatca cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg
     7561 ctggctaaat aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa
     7621 ataaacggtt gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc
     7681 aacttggcag gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca
     7741 gccttatcga agaaatctgt ctcgattgga cctggattca ctgtcgtaac agctacgcca
     7801 agtggtttca attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca
     7861 gaataaaccg ttgattttgc agttgccatt tttccagcca tagacgcgat attaatgata
     7921 tgaccttgtc ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct
     7981 aagatgttga cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg
     8041 aaaatcccaa aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc
     8101 ttttcatata attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc
     8161 tctttgccgc tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt
     8221 gcgcaactta taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga
     8281 ccgcctgaac tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct
     8341 cgcgaaatgg aatctcaatg ctatcaaaat ctttcatgat cgtcgtgttt tcaaacactt
     8401 cttgtgcttc tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag
     8461 taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg
     8521 aatggaaata gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca
     8581 gaatatcgct attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa
     8641 tagtcacgat tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc
     8701 catcttctag ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa
     8761 tacctaattc ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac
     8821 gataaccaaa actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat
     8881 cagtaaaaat cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg
     8941 tttgcgaaat acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct
     9001 ctaatggcgt atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa
     9061 tatgatcgcc gtgtaaatgt gtaataaaaa ttttaccgat ttttctcgga cgaatagtcg
     9121 ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct
     9181 cgtctaaaag tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac
     9241 ctgttcctaa aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt
     9301 ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa
     9361 cgttctaaag cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt
     9421 gagatcctct gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt
     9481 ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc
     9541 tttcgcatca tgcacatctt tttcgacatc ttcataatcc aagcgggtaa tttctccgcc
     9601 taattccatc attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat
     9661 cagtcctgta gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc
     9721 ttttatttct ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa
     9781 aatccctagc ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga
     9841 tttgttatta ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg
     9901 atcatggctg acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt
     9961 gatttctgaa aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg
    10021 tttgctcatt aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgta
    10081 aaataagaaa agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta
    10141 tcacagctcc tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct
    10201 cccttaaatc tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa
    10261 attcaaattc aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa
    10321 gagcttcatc cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat
    10381 gatcgaaatt cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg
    10441 catctgaatc acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag
    10501 tttcttcttc cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg
    10561 ctgtagcatt caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg
    10621 ggatgtcatc agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta
    10681 gattttccgg tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta
    10741 gcaagcgtaa gttataagta gataattctt tgttgatggc aagatagtct tcataaggat
    10801 ctcgtccttc catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat
    10861 gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca
    10921 agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttagggacga
    10981 gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag
    11041 tcgatttccc gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta
    11101 gttcgatttt tcgctcttgt cctggttcgc cgttttcagc aatttccggt gcaggattcc
    11161 gaggagaggc aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg
    11221 tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg
    11281 ttccttgtgg tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca
    11341 tcccattttc acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac
    11401 gtaacccttc atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg
    11461 gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc
    11521 cagctttcac atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt
    11581 attcatttat ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta
    11641 tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt
    11701 ttatcatttg gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa
    11761 tattctttgc gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac
    11821 agcaccccta ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt
    11881 gggcgtattg gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta
    11941 gtagcaatca acgacttaac aagtccaact atgttagcac aattattgca atttgactct
    12001 actcatggta cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc
    12061 gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac
    12121 ggtgtagata tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg
    12181 catttagatg ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc
    12241 atcgtctata acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt
    12301 tcatgtacaa caaactgttt agcacctatg gcttatttct taaataatga atttgggatc
    12361 gaagttggta caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga
    12421 cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat
    12481 tctactggtg ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa
    12541 ggacacgcac aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg
    12601 aaaacaaaag taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat
    12661 ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa
    12721 ggttcgatct ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt
    12781 aaaactgttg catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta
    12841 gaaaaattcg ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat
    12901 ccagtcaaag gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg
    12961 gcttaaaaat tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc
    13021 atgctcggct ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt
    13081 atctaacatt tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg
    13141 ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac
    13201 ttttgtcact agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc
    13261 tagctgataa gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt
    13321 cacattatct ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac
    13381 accgtataga acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg
    13441 tacatagtct ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg
    13501 tcctcttgca tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt
    13561 ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt
    13621 cgtttcagca ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca
    13681 atcgcttcgg ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg
    13741 tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt
    13801 ataaaaataa ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag
    13861 gattttcatc caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg
    13921 aattagtata atcaaagaat ctctactatg caatgttcat ttttataac
//
LOCUS       DAXLPY010000059        13947 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.059, whole genome shotgun sequence.
ACCESSION   DAXLPY010000059 DAXLPY010000000
VERSION     DAXLPY010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.059"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            136..309
                     /locus_tag="ACF3UF_002031"
     CDS             136..309
                     /locus_tag="ACF3UF_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672120.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            949..1422
                     /locus_tag="ACF3UF_002032"
     CDS             949..1422
                     /locus_tag="ACF3UF_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFD3672121.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="ACF3UF_002033"
     CDS             1431..1658
                     /locus_tag="ACF3UF_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672122.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="ACF3UF_002034"
     CDS             2294..2665
                     /locus_tag="ACF3UF_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672123.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="ACF3UF_002035"
     CDS             complement(2921..3163)
                     /locus_tag="ACF3UF_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3672124.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="ACF3UF_002036"
     CDS             complement(3195..4097)
                     /locus_tag="ACF3UF_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3672125.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="ACF3UF_002037"
     CDS             complement(4110..4298)
                     /locus_tag="ACF3UF_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFD3672126.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="ACF3UF_002038"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="ACF3UF_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFD3672127.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="ACF3UF_002039"
     CDS             complement(4913..5806)
                     /locus_tag="ACF3UF_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3672128.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6807)
                     /locus_tag="ACF3UF_002040"
     CDS             complement(5884..6807)
                     /locus_tag="ACF3UF_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3672129.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="ACF3UF_002041"
     CDS             complement(6856..7206)
                     /locus_tag="ACF3UF_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFD3672130.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="ACF3UF_002042"
     CDS             complement(7239..8141)
                     /locus_tag="ACF3UF_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFD3672131.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="ACF3UF_002043"
     CDS             complement(8134..8991)
                     /locus_tag="ACF3UF_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFD3672132.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9325..10134
                     /locus_tag="ACF3UF_002044"
     CDS             9325..10134
                     /locus_tag="ACF3UF_002044"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3672133.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10174..10671
                     /locus_tag="ACF3UF_002045"
     CDS             10174..10671
                     /locus_tag="ACF3UF_002045"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFD3672134.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11056..11129)
                     /locus_tag="ACF3UF_002046"
     tRNA            complement(11056..11129)
                     /locus_tag="ACF3UF_002046"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11093..11095),aa:Ile,seq:cat)
     gene            11316..11639
                     /locus_tag="ACF3UF_002047"
     CDS             11316..11639
                     /locus_tag="ACF3UF_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672135.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11803..12057
                     /locus_tag="ACF3UF_002048"
     CDS             11803..12057
                     /locus_tag="ACF3UF_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672136.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12127..12372
                     /locus_tag="ACF3UF_002049"
     CDS             12127..12372
                     /locus_tag="ACF3UF_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3672137.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12448..12813
                     /locus_tag="ACF3UF_002050"
     CDS             12448..12813
                     /locus_tag="ACF3UF_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFD3672138.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12874..13437)
                     /locus_tag="ACF3UF_002051"
     CDS             complement(12874..13437)
                     /locus_tag="ACF3UF_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672139.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4089 a         2577 c         2304 g         4977 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca tctttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtt gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac
     9181 tactatatat agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag
     9241 caagttagtt tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat
     9301 gtaaaaagaa agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg
     9361 cttgatcgaa atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa
     9421 aatggcggaa tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt
     9481 tccgaattag gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg
     9541 aaggatggaa aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga
     9601 aaagccttct tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa
     9661 gatgatcagc tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat
     9721 ttcaatttac agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt
     9781 agctatctta aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga
     9841 gatctgcaag cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg
     9901 cctacaggta tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa
     9961 tcgagtgaca tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc
    10021 gggttgagta ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta
    10081 acactgacga atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa
    10141 taaaatgacg atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat
    10201 catattcttg atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt
    10261 attgctcaaa gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat
    10321 ataccagttg aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt
    10381 ctttctccac aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa
    10441 actttagctg aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa
    10501 gtagtcggga ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct
    10561 tttcctgaag cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa
    10621 tccgctttag agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta
    10681 tcttcattta cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac
    10741 gtgctttttc tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca
    10801 cgacctcttt cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc
    10861 aaaatatgag gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt
    10921 cacaacctct tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa
    10981 gtaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggcagctt
    11041 tttcacaacc tcttatgtac cttgtaggac tcgaacctac gaccggacgg ttatgagccg
    11101 tctgctctaa ccaactgagc taaaggtaca tcataaataa aatttatttt tgttactttt
    11161 caactatagc acgaatgaca aactctcaca agtttcaaaa tataagtaaa ataatattgt
    11221 tattcttatt tcttttactt gtgtcataac tattttgtta ctttaatttt tatttgctta
    11281 ttttagaaaa aatgttattc ttttatttat tctcaatgtt aggagtgatt attttgccat
    11341 ttattgcgat tttattcgat ttagttgcgg cagcagctta ttttctccaa ttaaattatc
    11401 aaacctcagg aattctgttt attggaatga tttttcaagg tgtgattacc cttttgcttc
    11461 ttgtcatgat gctcagctat aaaggaaaaa gatatgcccg tattcaaaca aaagtatttg
    11521 ttaaatatgt ttccattcgc tatgggatca tcattctttc ctttttagtg aatgcgatcg
    11581 tcctcttttt atatgtattg aattacttag atatcaatcc attgattttt tctcgataga
    11641 taagacacat tcagcggaac agttcctgct tatcagcaga aaactgttct gctttttcat
    11701 ttttcattga tctattcttc ttttattttc ctagcatttc atttgtgatg tatgcaataa
    11761 catgttatct tttattatat gaatcgttga ggagtccgtt acatgattac gttggtgaga
    11821 gttttgtttt gggtgcctgc ggtcgcactg gtcgcaagta ttgtttatct tatgaattgg
    11881 aacaaagaac ggttttattt agctattttg actcttccgg ctatctactt tatgtggaaa
    11941 gtttttaatt acaactactt tgaacccgat agtgttttta tagaagaatt atcaggactg
    12001 gttttgtctt tattgatcgt cattctttat ttgatacgtt taaataaaaa acattgagta
    12061 ctattgattg catgtgtagc tttctatagt cattataact attctactat aatgaaaggt
    12121 gattaaatga gtatcgaaga agctatttta ctggatactt tacgttgtcg tctgaatttc
    12181 ttaagaactg gccgatcttt atctcaagta gctgtttcta gcgcgttaag tattccttta
    12241 ttcaaatatc gtaagtacga agaaggagaa gaaattccaa gcatcattga attaatctat
    12301 atcgctgact tttacgatat ttccgttgat tacctaattg gtcgctcaga aacagcaagc
    12361 aaactgaagt gattttttcc agccttggtg ctggtttttt catttaacgt ctaaggttaa
    12421 caatctatat ataaaggaga catttctatg cgattatggc atgaaaaatt gatttcaaag
    12481 cttcctcgtc aacagctttt aggacaacat cgggaatgct gtgcattaag aggaaatggc
    12541 tggggaaaga aacatgctac tgtggattat gtttttcact attctcctta tagattattc
    12601 caatatcatc agcttgtcat ggatgaaatg gaaaaacgtg gttacagccc agcaccagag
    12661 tggaaaaatc ctatgtatcg tggcaaatca tgcgaagcat tttttgattt acctactgta
    12721 gagcgcaacg tgccgattta tccggaacac gatgaagttt atctagcaga atgtttagca
    12781 aatttggagc aaaaaggaat ttatcttacc taatataact agaaaagcct tctatctcct
    12841 cttacttcat taaaaagctt taaccatctt agatcaagct aaaatgtcgt aagttttagg
    12901 gttatcttca tcctcacgtg caaaactaaa agcgtactct agttttggtt catcgccaac
    12961 ttccctagac ataaatgaac atctcctgac gtggtttaaa agtaccgcat cttcgacgtc
    13021 tgtatacgat gcacagcaca gattgcttct tttgatcttt cttttgattt ttctgttgct
    13081 tcttctacac cttcttcgat tactacatcg atgcttacaa ttgcttctgc ctaatattcc
    13141 catgcatcgt cgatttaagc ctctgtagtc actgtgatcg tttccacatt ttaactcctc
    13201 tgtcgtggct tcagttgatt ttgtgatcag ttcagttgct aagccagagt cagaacaacc
    13261 tgccattgct agcgttaata ttgatagtaa aaatagtttt tttatcataa ggttcccccc
    13321 ctgaaaatag actaaaataa taacgctttc tttttttgtt ttcagacgaa aattaataat
    13381 ttctaaatat tctttaaaaa agcttataac tattatgcct tttttaatat ataacacagt
    13441 tatttttaaa aataagaatg ctaaatcact ctacaataac ggcgaaagca caaaaaataa
    13501 aaaaattatt acgttattaa aaaaacagat gaaagatcag gttttattag atctcattct
    13561 ttcatcactt gaagggattt aatgaactac tttttcctct ttgtcgtttt tatatattcg
    13621 tattccttca aacagtagga tagcctcttt caatgcttga tatttgaact gtccgttact
    13681 taaaaattta gatgtgccgc cctcttccta gaacatattc ttttttactt tttcattaat
    13741 tgacagacca atcgaacgaa actgtaaatt tcgataggat aatgattggt caaactcatt
    13801 cattttcaag acatctcgat tcatattcaa gataggaatc tttttatcaa catcacttta
    13861 ttcgtatttt cctctaccat aaaagcttca cgctccacaa aattgtttta tacactacta
    13921 ttcagcccat tcaacgacca atgaatt
//
LOCUS       DAXLPY010000060        13710 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.060, whole genome shotgun sequence.
ACCESSION   DAXLPY010000060 DAXLPY010000000
VERSION     DAXLPY010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.060"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            201..2672
                     /locus_tag="ACF3UF_002052"
     CDS             201..2672
                     /locus_tag="ACF3UF_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3672140.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2775..4511)
                     /locus_tag="ACF3UF_002053"
     CDS             complement(2775..4511)
                     /locus_tag="ACF3UF_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3672141.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4508..5212)
                     /locus_tag="ACF3UF_002054"
     CDS             complement(4508..5212)
                     /locus_tag="ACF3UF_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3672142.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5343..5846
                     /locus_tag="ACF3UF_002055"
     CDS             5343..5846
                     /locus_tag="ACF3UF_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFD3672143.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5806..6144
                     /locus_tag="ACF3UF_002056"
     CDS             5806..6144
                     /locus_tag="ACF3UF_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFD3672144.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6165..7583
                     /gene="ffh"
                     /locus_tag="ACF3UF_002057"
     CDS             6165..7583
                     /gene="ffh"
                     /locus_tag="ACF3UF_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFD3672145.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7695..8273
                     /locus_tag="ACF3UF_002058"
     CDS             7695..8273
                     /locus_tag="ACF3UF_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFD3672146.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8277..8798
                     /locus_tag="ACF3UF_002059"
     CDS             8277..8798
                     /locus_tag="ACF3UF_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFD3672147.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8877..9431)
                     /locus_tag="ACF3UF_002060"
     CDS             complement(8877..9431)
                     /locus_tag="ACF3UF_002060"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFD3672148.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9684..9959
                     /gene="rpsP"
                     /locus_tag="ACF3UF_002061"
     CDS             9684..9959
                     /gene="rpsP"
                     /locus_tag="ACF3UF_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFD3672149.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            9971..10222
                     /locus_tag="ACF3UF_002062"
     CDS             9971..10222
                     /locus_tag="ACF3UF_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFD3672150.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10347..11138
                     /locus_tag="ACF3UF_002063"
     CDS             10347..11138
                     /locus_tag="ACF3UF_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672151.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11308..11829
                     /gene="rimM"
                     /locus_tag="ACF3UF_002064"
     CDS             11308..11829
                     /gene="rimM"
                     /locus_tag="ACF3UF_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFD3672152.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11819..12580
                     /gene="trmD"
                     /locus_tag="ACF3UF_002065"
     CDS             11819..12580
                     /gene="trmD"
                     /locus_tag="ACF3UF_002065"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFD3672153.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12716..13063
                     /gene="rplS"
                     /locus_tag="ACF3UF_002066"
     CDS             12716..13063
                     /gene="rplS"
                     /locus_tag="ACF3UF_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFD3672154.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13423..>13710
                     /locus_tag="ACF3UF_002067"
     CDS             13423..>13710
                     /locus_tag="ACF3UF_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672155.1"
                     /translation="MGKDKRIVWKDQSDLKIILTISQFIETYEIKSSREYQKQLSKNP
                     HSAPSMWFIINKYGSWNNLLNSIGIDNNGSKKWARMETDELIKVAQIFIDSE"
BASE COUNT         4570 a         2482 c         2808 g         3850 t
ORIGIN      
        1 aaacgaagaa aaagtgttag tagaaaatcg ccttcgattt tccaccaaca caaaatatta
       61 tagaaccctt tttttttgct atatgacagg aatgaaaggt gtttgcaagc ttaatgtgag
      121 gaacactttc catatctgtt ctatactgga taggagaagt ttggaaatat ccagaaaacg
      181 aaatcaatcg aggtagccac atgaagaata aatggataaa tcgaagtaaa aaaaagaaag
      241 taacacaaag atcatcagat aaagtcatcc gtctttttcc atcgtataaa gaaggattaa
      301 cggcagatca agtcaaggaa cgaatagaaa aaggtgcagc aaataattca gtcgatccca
      361 cattcaaaac aaatcagcaa atcgtattgg aaaacatatt tacgtatttc aatttgatct
      421 ttcttatctt agccattttg ctttgtttag tagaatccta taagaacttg acttttttac
      481 cagttatcat agccaataca ggaatcgcca tttttcagga aattcgatcc aaaaagatct
      541 tggacgaact aaatgtttta aatacagcaa aagtcaatgt catacgagac gggatagaac
      601 aaacaataga tatagaagac cttgtaatag atgacattgt tattttagag actggatatc
      661 aaattccagc agatgcagag gtcgtggaag ggaaactgca agttaatgag gctttattga
      721 caggcgaagc agatgaaata accaaagaaa taggtgatcc attaatgtcc ggcagtttca
      781 ttgtttccgg aaaagcttac gcccgattag acaaagttgg agcagattcg tatatttccc
      841 agctgacagt caaagccaag acaatgggag aaggagaaca gtcggagatg attgcttctc
      901 ttaatcaatt gatcaaatgg attgggatca tcattattcc tatcggtatc ctgctttttt
      961 ctcaaagtta cttttttaat ggaaacacga tcaaagaaag tgtcgttgca atggaagcag
     1021 cattgatcgg tatgatacct gaaggactgt acttgctgac gacgattgca ttagcattaa
     1081 gtgcgactaa actagcaaag caaagagttc ttttacacaa tatgaaaagc attgagacat
     1141 tggcaagggt aaatgtcctt tgtgtagata aaacaggaac gatcacagaa aataaaatgt
     1201 ctgttcaaaa aatgatcgtc tctaaaaaac aagaaataat cagtcagtca gatcaattgg
     1261 aagcatgcat tgctgactat gcaaaagcga tggcaggaga caatgcaaca atggaagctg
     1321 ttaaagcata ttttacaaaa accactgatc aatcctatca ccatgttatt cctttttctt
     1381 ctgtccaaaa attcagcagt gtagcgttgg cagacaaggt gtatgtttta ggagcgcccg
     1441 aaatggtttt gcgcgatcaa ttgccggaat atgcggaaga gtttgtttct ttcgctgaaa
     1501 aaggctatcg cgtgttggtc tttggtgtgt acgatgggat tcttgaagaa ccagtattga
     1561 cagaagcagt cacaccatta ggctatattc tgattgctaa tcctatcaga aaagaagcaa
     1621 gagccacatt tgattacttc aaaaaacagc aagtagccat caaagtgatt tctggagata
     1681 atccgctcac cgtatccaat gtagctgtcc aagcagggat ttcacatgct gatcagtacg
     1741 ttgatgcatc taaattatca gaagaagaat atgaagcagc tgtcgaaaaa tatacagttt
     1801 ttggacgcgt caagccagaa caaaagaaaa tcttcgttca attgataaag cgtaacaata
     1861 cagtagctat gacaggtgat ggcgtgaatg atattctagc catgaaagaa gcagactgca
     1921 gtatagcgat ggcttccgga aatgaagccg ccatgcaggc ctcacaagtg gtcttacttg
     1981 attctgactt ttcacgcatg ccagaagttg ttgcagaagg acggcgcgtt gtgaacaata
     2041 ttgagcgatc agccagcttg tttttagtga agaatatttt ctcctttttg ctctcactgt
     2101 tttcagtgat ctttgctctg acctatcctt tagaaccatc acaaatcaca ttgattagtt
     2161 tgtttactat cggacttcca tctttcttgc ttgctctaga agaaaacaaa aagcgaatca
     2221 gagggaaatt catcatgaat gtgatggaaa aagctgtgcc aggtggacta acagatatga
     2281 tcgtagtcgg tgcgttggtg atctgcgggg tgactttgaa tctaaataaa acagatgttt
     2341 ctacagcatc taccatgctt ttgattgcag tagggttcct cgttctctat aaaatctgtt
     2401 caccgctgaa taaattcaga agtcagatca ttcttttctg tgctagcggt aacttttttt
     2461 cggtcatctt tttgcataag ctgttttcaa tcaccggtat ctcagctgta tcacttttgc
     2521 tgttgagcat tctatttttc tcggcagatt cgatttttag gcatttgacc acattggtag
     2581 aatatttgtt tgaacgtaaa aatgaaaaag agcaaaagcc gtttagtcgc gtagctaaaa
     2641 aatttctatc gatatttaaa cgagaaaatt gacgaaaagt atctcaaaaa agagtaaaaa
     2701 agaacaacca ctcgtgtatc tttcgaagca ggatgagtca tccaacttta aaacgcacga
     2761 gcagttgctc ttttttacat tttcggaatg gtaacggtga aagtcgaacc tgttccaaga
     2821 tgactgtcta cagtaatcgt accattaagg agttgcacgt agtcttttac aatcgctaac
     2881 cctaatccgg tcccgcctga atgtcggctt cgcgccttgt ctacgcggta aaaacgctca
     2941 aagatccgtt cctgatcctc aatgtcgata cctataccaa agtcttggac agaaaacgat
     3001 agatcatctg ttgcctgata gcggataata atctcgctgt cgctttttga atattggaca
     3061 gcattttcaa tcagattttt gataattgga taaaggatat ctgttttagt agtaaatggt
     3121 tcgttctttc caatcaatcg aatcgtcaac cgtttctttt cgatgattgg ctgataattt
     3181 tgaacgattt gctggaaata aggttctgta taaattgtct ggatctcgta agaattctcg
     3241 ccatcttttg acagctggat gatttcccga atcagtttat ctaaccggat cgcatctttt
     3301 tgcatgatct caagaaaaga agtcagagtt tgcgggtcat cttttgcacc atccagtaaa
     3361 gtctcggtaa aaccaatcag tgaagtcaca ggagttttta attcgtgaga gacgttgcca
     3421 acgaaatcct tttgtagctt ttctaaacgt cgcactttcg ttaagtcata cgccacccct
     3481 agaatctgtc cggtaccttc tgaattagta aagtagcgca aactcaagtc taatgtctgc
     3541 cgaccttctg taagggtgat ctcctgatgg atcagcggat gctcaggagt cacttgatga
     3601 atcagctgaa tgagttttgg ctcttgaatg acttctgtgt accgctgttc aggttgatag
     3661 cttaccacgt ttaaatgtag ctgcatcttt ggattaagca gtagtaaacg agaatcagca
     3721 tcatcaatca ggaatacgcc aatcatcagt tcgttcagta acgtatataa ttgctcttct
     3781 gtggtagtac acgcccgata catcttactc atttgttcgc tcaacgcatt aatcgtctga
     3841 tacaattctt cccattgatc gggtgtttgc atgattactt ccgcctgatt aggattttgc
     3901 accatttttt ttagtacggg cagcacggtt ttcaatggct ggtttttttg atagatcaga
     3961 taatagatca ttcctgcaag aacaaggaag aaagacagaa agaagaaaaa gacccaacgg
     4021 cgaaaactct cagttctcgg taaaaaaacg cttgtcggtt ctgcgatacg taaaatggct
     4081 tctaactggc cacttttttt gactggtaat gcgacatata aaagatcctc attcaaagta
     4141 gtacttttgc gcaaagcgct acctaggttc ccaccattca atacggcttt gatttcggga
     4201 cgggagtttc gctgttcatt caatgtttca ttgtttgtgt caaataagat ctttccagta
     4261 gcatccatta aagtaatccg ttcgttcgac tgatggacga attcttccaa agcagttttg
     4321 ttttgcgctg cttggaggtt ttcgacatct aattgccgga tcagcagttg tgcttttttt
     4381 gtcaggtagc tttcttgctg ttccacgatc tgctgttgaa aataatggga aatcaattgc
     4441 cagccaccaa aaaacaaact aactaaaaga ataagaaaga agagacgttc ataaattttt
     4501 ttccatttca tcgtttgggt tcctgaaact tatagccaaa tcctctaata gtcaccaagt
     4561 actttgggtg ttttggatct cgctcgattt tttctcgcaa atgactaacg tgtacatcta
     4621 cgattcggct ttgtcctgcg aagtcaaaat tccaaatgcg gtctagcaat gtgtctcggt
     4681 cgatcacacg gtcttttcgt ttcatgaaat aaacaagtaa ttcaaattct ttcggtgtta
     4741 gttcaatcag atggtcgtct acggtcactt gataattggt caaatcagca gtgatttgtc
     4801 caatcgatag atattcaggc tcagcttcat cttttgattg cttacgaggt tcaattcgtc
     4861 tgaatattgc tttcatacgg gctaatactt cgcgaggact aaatggtttg gtcaaatagt
     4921 cgtcagcacc tatttctagg ccaatgatcc gatccacttg gtcatcttta gccgtcagca
     4981 tcaaaatcgg tgtttcattt ttttcttgac gcagccgctg agtgatctcc atgccatcca
     5041 tcgttggaag catcacatct aaaatgatga aatcaaatga ttgttctaat gctaattcta
     5101 atccttcgcc tccatctgtg gcactggtta ccttgtagcc ttctttttcc aaattgaacg
     5161 tcaagagcgt tacaatagaa ggttcatcat caacaactag tatttttttc attcaaatct
     5221 cctttaaata ggtttcattc tgtttatatt ttagcataga atcagtacaa agggctattt
     5281 tacaaaagaa ataaatggta taataggaag gcactttgct gaatagaaag gaagagcagt
     5341 caatgattgg aatcagtgca tgtttaggcg gtctggcctg tcgctatgat ggacagaaaa
     5401 aagaagtacc agaattgatg gaactagttg aaactggaga agctgtcatg gtctgtccag
     5461 aagtgatcgg cggattacca attcctagag atcccgctga aatcattggt ggaaatggat
     5521 tcgatgtgtg gaaagatcaa gcaaaagtat ggacgacaag cggcgaagat gtaacggaag
     5581 cgtacaaaaa tggcgcgatc aaagcctatc aaaaattgca ggaaaaacac attgatctag
     5641 tcatcatgaa ggaaaaaagc ccttcatgcg gaacccattc gatttatgac ggaagttttt
     5701 ccggaataaa aaaaaatggt gccggagtgg ctactgctta ttttattcag caaaaaatga
     5761 ctgtgctctc tgatgaagaa tggctgaaaa ctagaggtga gcagaatgga aatcgaaaag
     5821 accaatcgaa tgaacgcgct ctttgaattt tattcgacct tattgacaga aaaacaaatg
     5881 aactacatgg aattatatta tgcagatgat ttttcattag gtgagatcgc ggaagaatac
     5941 gaagtaagcc gacaagcagt atatgacaat atcaagcgga caagcaagat cttggaggat
     6001 tatgaaaaaa aactccatct tttttctaat tatattgttc gagaacaggt attggaaaat
     6061 atgactgcat atattacaga taagtacccg gaagataaaa aactacttga atatgtacag
     6121 caaattcaag caatcgaaga ataaataaaa ggaatgaaga aaatatggca tttgaaagct
     6181 taactgaacg tctccagcag gcgatgggaa aaataagaaa aaaaggaaaa gtatcagaag
     6241 ctgacgtaaa agaaatgatg cgggaaatcc gccttgcctt actagaagcc gatgttaact
     6301 tgcaagtagt caaagatttt actaagcgcg tacgcgaacg tgcggtaggg gcagaagtgc
     6361 tggaaagttt atcacctgca caacaaatcg taaaaatcgt tgatgaagaa ttgacgatca
     6421 cacttggttc tgaaacagca gagttaaata aatcaccaaa aataccaact gttatcatga
     6481 tggctggtct tcaaggggca ggtaaaacga cctttactgg taaattagcc aattatttaa
     6541 agaaaaatga aaatgctcgt ccgctcctaa tcgcagggga cgtatatcga ccagctgcga
     6601 tcgaccaatt gaaagtatta ggtcaacagc tagacgttcc tgtatttgat atgggaactg
     6661 aagtcagccc ggtagagatc gtccgtcaag ggatggagtt agcaaaagaa aagaaaaacg
     6721 actatgtatt gatcgatacg gcaggacgtc tgcatatcga tgaaacattg atggatgagt
     6781 tgaaacaaat caaagaattg acgcaaccaa atgagatttt gcttgttgtc gatgccatga
     6841 ctggtcaaga tgccgtcaac gtagctgata gcttcaacca gcaattaggt attacagggg
     6901 tcgtcatcac taaacttgat ggggatactc gaggcggggc agcactatcg atccgctcag
     6961 tgacaggcgc accaatcaaa ttcatcggtt ctggtgaaaa attgactgac ttagaagtat
     7021 tccacccaga tcgtatggct agccgtatcc ttggtatggg ggatatgctg acattgattg
     7081 aaaaagcgca gcaagactac gacgagaaaa aagcggaaga acttgcacag aaaatgcggg
     7141 aaaattcatt cgatttcaat gactttattg aacagcttga tcaagtgatg ggtatgggcc
     7201 cactggaaga tctaatcaaa atgatcccag gaatgaatca agtccctgga atcgaaaacg
     7261 tcaaggtaga tccaaaagat gttgaacgca aaaaagcgat ggtttattct atgacgccag
     7321 cagaaagagc aaatcctgat ctgttgaacc caagccgtcg tcgccgaatt gctgccggtt
     7381 ctggaaacag tgttgttgaa gtgaatcgaa tgatcaaaca attcaaggaa tcaagaaaaa
     7441 tgatgcagca aatgtccaaa ggggatatga acatcccagg tatggaccaa atgtttggtt
     7501 caggcgtcaa aggaaaacta ggcaaaatgg cgatgaatcg aatgatcaag aaaaataaga
     7561 agaaaaagaa aaaacggaaa taagatgaaa aaaacagctt cggtacagac tgaaaatgtc
     7621 tactgccgga gcttttctat cagcaatttt tattctttac taatacaatt actctaaacg
     7681 aagaggtggc acagatgaga tgtccgtgga gtgaacaaac agaaagtatg cggcaatatc
     7741 atgatactgt ctggggtgtt cctgaatatg atgaccaaaa gctgttccga aaattgatgc
     7801 ttgatattaa tcaagccgga ttgagctggc agacgatttt aaataaaagt gaagcattcg
     7861 atgaagcata tgatcgattc gatatcaaaa aagtcgcaaa ttatggagaa acaaaaatca
     7921 gtgaactaat ggaaaacaaa ggaattattc gtaaccgaag aaaaatcgaa gcagccgtcc
     7981 aaaacgccaa agcagtcttg aaaattcaag aagaaatcgg cagtttttca gagtatcttt
     8041 ggtcgttttc taatggaaaa atcgttgatt cttcttatca ttcacaagaa gaagtcccaa
     8101 caacaagtcc tctttcagat gaattagcaa aagatctaaa gaaaagagga tttaaattta
     8161 tcggaagcac aacaatctat gcttttttag aagctgtcgg gatcatcaat gatcaccttg
     8221 acagttgttt ccgcaaagaa gaggtcgtac gtatcggcag aaagggcgaa taaagcatgc
     8281 gaaaaatcat attttatggt gctataagtt tagatggcta tttggcaacg aaaacggatg
     8341 atcttcaatg gctttttgac actccaacag gtaagcaaac tacttatgaa gctttttatg
     8401 aaacaatcga tacgaccatc atgggcagaa aaacttatca ggaagcaaaa aaatatttgg
     8461 agaccgaagc aatttatcca gagaaaaaga atttcgtttt ttccacccac gcacaattac
     8521 aattgccaga tgctgaggtc gtaaacgaag atcctgttgc ttttctaaaa aatctacaaa
     8581 tgacagaagg aaaagatatc tgggttgtgg gtggcggtcg attgatcaaa ccgctattgg
     8641 aacatcaaat gattgatgaa tggtatatcc agattacccc tgtattatta ggggacggga
     8701 ttcctttatt ccaaaaagga acatatgaag cgcgttttga aatgctagac acgacacgat
     8761 tcggtgaatt tatcgaattg cattatgtac gaaagtagaa gtaaataaaa taaaaaaggc
     8821 aactatatgc agaaatgtcc tgtacatagt tgcctttttt attaccgtta tgctttttac
     8881 tctgttaatt tgttagaaaa atctagatac gcatctaaaa tcgtttggaa gaaacttaat
     8941 gttccttcaa cgatattacc attttcatca attagattcg caacgtttcc gatatatgct
     9001 tccggttgct gcaaggttgg cacattcaaa aagacaagtg attggcgtag atggtggttt
     9061 gcgccaaagc cgccgatccc acctggtgat gcagtaacga ctaaacctgg tttatgatcc
     9121 caaacactgt gtccataagg tcttgagcct acatctaaag catttttcaa tactgctggc
     9181 acagaacggt tgtattcagg agtaacgaaa acgacaccgt ctagtcccct cacttcctca
     9241 cgaaaacgag tccattcagc aggagcctgt tctggagttt cgagatcctc attgtaaaat
     9301 ggcagatcat cgatttttac aaatacactt tcgtaccctt caggaagcaa tttcgcaaaa
     9361 gcttctgcta cttttttgtt gtaagaatct tttcttaaac taccaataaa aaatccaatt
     9421 ttttttgtca tacgattttt cctccttcaa actatctata ataatcttac aaaagataag
     9481 taactggagc aaataaaaac acttactgac aaaagctaca tagaagatag attacttatt
     9541 tttaacaaaa aagaagtcta aaatcttcta ttttctaaaa aaaatcgaat ttaatcaagc
     9601 tgtaaagaaa aaaagcttta cagggtaaaa aaaaactgtt acactacatc ttgtgaataa
     9661 aacaatggag gtggaaataa ataatggcag ttaaaatccg tttaaaacgt atgggttcta
     9721 aaaagagtcc gttttaccgt atcgtcgtag ctgattcacg ttctcctcgt gatggacgtt
     9781 tcatcgaaac tgtaggtact tacaatcctt tgaaagaccc tgcagaagta gttttaaaag
     9841 aagacttagt tcttgactgg ttatcaaaag gtgcacaacc ttctgacact gtacgtaaca
     9901 tcctttcaaa agaaggcgtt atgcaaaaac accacgaagc taaattctca aagaaataag
     9961 gtgaccggat atgaaagatt taagcgactt agtcttaaca atcgttcgtc cgctagtcac
    10021 ttatcctgat caagtcaagt tagacgtcgt agagtcgaaa gacttttacg agtacaatct
    10081 aacagtggct cctgaagata ttggccgtat cattggaaaa caagggcgtg ttgctaaagc
    10141 aatccgcaca atcgtttacg gtgttcggat caatgcaccg aaaaaagtgc gtttgaatat
    10201 catcgatgat aaggaaaagt aaataaacgt gctgtactcg aattttcgag tgcagctttt
    10261 ttgttttttt tattaattga agaaatgatt atttggcaaa acaagcaaga aagcgtatcc
    10321 ttataggagg agggagtgaa cagccaatga gaaagaaaat gttatttatt ccatttgctc
    10381 tattgttaag cgcttgtagt tcggttactc aagaatcaga caatacacat ctatcaagca
    10441 gtatatctga aactgttacc agtccagaaa aaagtagtac caaaacggct tccaccactg
    10501 aacaaacaat ggctacctca aataatgaga aaaagactgc tttagaccag ttgaaagaac
    10561 aacagccaaa tgttcccatg cctctagatg taccagtctc ttcaggctat ctcaatatcg
    10621 cagcgacaca tacaaagcaa ggttattcta ttttatatta cagaacagat cgtcccctcg
    10681 ggttgaatgc tgacgaattg aatcaagaaa cgcctattgc aacctatcta tatcaatatg
    10741 ggtttgcttc tagtcaagaa acaatccaag ttttgcagcc atttgagatc gacacaaatg
    10801 gtcagcaagt ggacttaggt tctcgaatca cagggtatca gcaaggtgca gcaggttcaa
    10861 gttttcttga atggcaagaa ggaaactggc gtattcgaat ccgtgggaat aatatagaag
    10921 gccaagatcc cttactatta gctaaagaaa tcgtagctta tttggaagaa aacagtctac
    10981 cagcacctga acaatttggt aaaattactg ttgatatggg tgatacgacg aatcgagccg
    11041 tagaagtaag ctggcaagaa ccgaaaaatg cctatacgat cactcatcaa gatcctatgt
    11101 ctgcgttgaa gatggcagtt tctatgaaga ggttgtgaaa tcagcgcgct gatctgagcc
    11161 catcatttaa ctccaagtca caggaagtaa tcaaaaatag cacgccgcat ttttgcataa
    11221 ttttggctta ataccttaaa agaaaactag aattgcctct tcacacatgc taaaataaaa
    11281 cagacaaaaa agaaatgggg atataagttg actgaatact tgaatgtagg aaaaatcgta
    11341 aacacacaag gtatcaaagg cgaagtccgt gttatctcaa caacggattt cccagaagaa
    11401 cgttacaaaa aaggaacggt gctaacacta ttccaagacg gaaaagcacc tgtggaatta
    11461 acagtcaaaa gtcatcgcaa acataaaaat tttgacttat tgagttttga aggacatcct
    11521 tctatcaatg atgtggaaaa atatcgggat ggcatattaa aagtgtcaaa agacaactct
    11581 gtagatctag ctgaaaatga attctattac catgagatca tcggtctgca tgtattagaa
    11641 gatggaactg agttaggtaa agtaaaagaa atcttgtcac caggtgccaa tgatgtttgg
    11701 gtcgttcaac gtccgaaaaa agctgatata ttgcttccat atatcgcttc tgtcgtcaaa
    11761 gaagtcgatt tagaagctgg agtggtccgt gtagaaattc cagaaggact gattgacgat
    11821 gaagattgat gtattgactt tatttccaag aatgtttgaa ggtcctatgg gggaatccat
    11881 catcggtaag gctgtagata aaggattatt agatatcaat atctctaact tccgcgatta
    11941 ttcagataac aaacatcaga cagtagatga ttatccatac ggcggtggag caggtatgct
    12001 gctcaaagtc cagcccatct atgataacat ccaagccatt gaaaaagctg caccggatgt
    12061 caaaaaaaga gtaattcttc ttgacccagc tggtaaacga ttcgatcaga aaatggcaga
    12121 agaattttca caagaagaac acttagtatt catttgtggt cattatgagg gatatgatga
    12181 acgtatccgc acattagtga cagatgaagt ttccttagga gattatgtcc ttactggggg
    12241 agaattaggt gcgatggtca tgatcgatgc aacagttcgg cttttgccag atgtgttagg
    12301 gaatcagact tcagctcaaa cggattctta ttcaaccggt ttattggaac atccccaata
    12361 tactcgcccg gcagaatata aagggatgaa agtaccagaa gtattgacaa atggaaatca
    12421 taaattgatt gaagaatggc aattaaaaga atcactaaga aggacctatc aacgtcggcc
    12481 tgatcttttg gaaacacttg aatggacacc tcaaatgacg aaatttttag aagaaatcaa
    12541 gaaagaagaa caagaaaaaa cagcagatga agccaagtga ctttttctaa aatcttcttt
    12601 acagtaggtt gataatatgt tagtatttta tggtgagtgc aaaagcactt aactattacg
    12661 atattccgct gtgagaaaag ctcataagaa tatttggaat aaggagaaga aaaccatgaa
    12721 tccattaatc gaagaattaa caaaagaaca attacgttct gacatcccag cgttccgccc
    12781 tggtgacact gtgcgtgttc acgcaaaagt tgttgaaggt actcgtgaac gtatccagtt
    12841 atttgaaggt gttgttatca aacgccgcgg tgctggaatc agcgaaactt atacagtacg
    12901 taaagtttct aacggagtgg gcgttgaacg tacattccca ttgcatacac cacgtgttgc
    12961 aaaaatcgaa gtagttcgct acggtaaagt acgtcgtgca aaattgtact acctacgtgc
    13021 attacacgga aaagctgctc gtatcaaaga aatcagaaga taaacacgga aaacttcctt
    13081 ggaaatctga aatctgtgaa aagtccttgt atatcaagga ctttttcttt tttctctatc
    13141 acatttttaa tatgttttgg gccttttttt ctaatgttct ctcaaattgt cctgaatctc
    13201 ccaatattga ctactattat cgtcaaaata ccgaaaaaat tagtagtcat tttgacgaca
    13261 aatttaatac gaaaaatacc taaacactta ccgaatttag caatttttga acccgagttg
    13321 ctaaaaaggt tgaatgcttt cgaaaaaagc aaaacatata ccattgtgct aaaaagttta
    13381 tgtgataggt ttctatttaa ataattttag gagttttttg taatgggaaa agataagcgt
    13441 attgtttgga aggatcaaag cgatttaaaa attatattaa caattagtca gtttattgaa
    13501 acttacgaaa taaaatctag tcgagaatat cagaaacagt tatcgaaaaa tccacattca
    13561 gctcccagca tgtggtttat tattaataaa tatggctcgt ggaataattt gctgaatagc
    13621 attggaattg ataataacgg atctaaaaaa tgggctagaa tggagaccga tgaattaata
    13681 aaagtggcac aaatatttat tgattcagaa
//
LOCUS       DAXLPY010000061        13688 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.061, whole genome shotgun sequence.
ACCESSION   DAXLPY010000061 DAXLPY010000000
VERSION     DAXLPY010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.061"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..661)
                     /locus_tag="ACF3UF_002068"
     CDS             complement(<1..661)
                     /locus_tag="ACF3UF_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672156.1"
                     /translation="MKSKIILGGLLLSTTAFVSLQSPQITSAESLTNSAEIIVPLNLK
                     VKAHYTNGLPLEAGKEVRLRNLTDGSTEVLKKQVDANGEVIFTEQDGIKKEVNYGIET
                     DGVRNGYTVRYDLGGEKEKDITVNLPGSELPLSLKVKAHYTNGLPLEAGKEVRLRNLT
                     DGSTEVLKKQVDANGEVTFTEQDGIKKEVNYGIETDGVRNGYTVRYDLGGEKEKDITV
                     NL"
     gene            complement(1090..2280)
                     /locus_tag="ACF3UF_002069"
     CDS             complement(1090..2280)
                     /locus_tag="ACF3UF_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HFD3672157.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFKGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGAFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            complement(2866..3270)
                     /locus_tag="ACF3UF_002070"
     CDS             complement(2866..3270)
                     /locus_tag="ACF3UF_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3672158.1"
                     /translation="MTNEIILMSHGLMAEEILNSAKMILGNQINYPVVSMTQNDGIEG
                     TINKLNKILEETSDIRNIIILVDLMGGTPANVAMMKASMDKRIQVVTGMNLGMVLESY
                     FKINEEKLAEHLIEIGKSSIKIPEIQMDGGEE"
     gene            complement(3285..3767)
                     /locus_tag="ACF3UF_002071"
     CDS             complement(3285..3767)
                     /locus_tag="ACF3UF_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFD3672159.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDTVANND
                     IQKQVLRMAVPAGISSSIITEEKAITNIKNGKYEGQNVLLIVKSPVDLLSFIENDLQI
                     DRINVGNMSNRKGTTVLRPNISVTNEERNAFEKLLNLGVEITTIMTPDDKKTYLKDIL
                     "
     gene            complement(3787..4599)
                     /locus_tag="ACF3UF_002072"
     CDS             complement(3787..4599)
                     /locus_tag="ACF3UF_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3672160.1"
                     /translation="MNSLETTKLGVNSKIKKSVLWRWFFTSSVSSNYEKMQALAYCYA
                     VLPFLKVTYKNKPEALQKAVLNHLQFFNTNPWVAPYILGINIAMEENSDENTEEAVTS
                     IKTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPVGIILWIAVSVALKMISIPL
                     FRIGYTSGTKLITTIEKSLKLLTESTSILGLMVVGALIPSVVKTNVVLDFKQGDFSMR
                     GQEILDQIMPGLLPALLVGLVYWSLKKNVKPIYLILGVMVLSIVLATLGILK"
     gene            complement(4592..5377)
                     /locus_tag="ACF3UF_002073"
     CDS             complement(4592..5377)
                     /locus_tag="ACF3UF_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3672161.1"
                     /translation="MEISVIQLGLIVLYGFFINFEKNSTMFGTYQPVTAGFVTGLILG
                     DIKTGLFIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTGQESSVGISIGIPV
                     ALLMVQLDIIRNTIGIWMVHKAEAGVKRGDYSMISKMQMFGVFLTAATTGIPVALAVI
                     FGPSLINTILAHTPEWLTNGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVMSVY
                     LKMPLLGVALIGAAIALIIYKKNSQNVINNTVVNTIGGMDEDE"
     gene            complement(5377..7452)
                     /locus_tag="ACF3UF_002074"
     CDS             complement(5377..7452)
                     /locus_tag="ACF3UF_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HFD3672162.1"
                     /translation="MKEVINIESNYFSRKFDDELLIIEAWGENAIRIRSFVDMNYEDR
                     QNSLIDKPNSLNKVIINQYENKTELINGKIRAVLDHRDRLTFYNEKNDVLLKEYIRLR
                     AVKHDDGGEDAGSVEVTKDFNSTLKLKSREYRSNMDGKFQVTTRFESDPKEKIFGMGQ
                     YQHSYLDLKNTVLELAQRNSQVSIPFYISSLGYGFLWNNPGIGEVSFAKNITRWKMYS
                     SDYIDYVIISGNEPKEILRNYSNLTGKVPKMPDSLLGLWQSKLRYRSPEEVMDVVEKY
                     HKRGIKLSTIAIDYFHWPKQGEYCFDEEYWPNPEKFLKTLKTDYGVEPIISIWPTVQT
                     DAENYEKYLENGYLVKVNRGVRLTMQIQGNTIFIDMTNSEARKYVWSLIKKNYVDKGI
                     NYFWLDVAEPGYSVYDFDNYRYKKGTDLYSGNLYPIDYLSMIYEELSNEQPVITLVRG
                     GWAGAQRFGALLWSGDIDSSFEAFRNQVNTGLNVGLAGIPWWTTDIGGFHGGNPEDPE
                     FRELLIRWFQYATFSPILRMHGDRLPHSKPLSDHGGGSMVTGAPNEIWSYGIEVEQIL
                     TKYIKIREALKPYISTLMDKAHRFGDPIMRTLFYEYPSDNNTWAVEDTYLFGDTFLIA
                     PIVNYKETVREVYLPINENWTNIWTGEEYDGGQTLDVEADISMIPVFIKTNQKDKFSK
                     LLSIIKEEI"
     gene            7760..8926
                     /locus_tag="ACF3UF_002075"
     CDS             7760..8926
                     /locus_tag="ACF3UF_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3672163.1"
                     /translation="MISSKYTIREQNEAKILNQIIRHKEISRAELSKITSLNKASVSS
                     IINKLIDDSLVIENRIGEATNRGRKPIMLTFNGVSSGLAIAIDLGYNYIDGMVASLDG
                     KEIARIQLTDTYVSKDNIQMLIRKIIKKLTDNLPYTRHGIIGMTIAVQGQVLNNKVLS
                     TTYNGLEEIDLVKLLNQEYSFPVFLQNEANLSALGEYTFSSDIENLVSISLHSGIGVG
                     VVKNGKLDIGNKGYAGQLGHTILFPNGRKCECGNYGCLEKYCSTQVIYQEISKEKKLD
                     KINSDIVEYLYSNKDQKVVEMIELYAYYLSIGINNIVMLYAPELVIFNSPLTKKIPNI
                     INIIKNFLNNQYTKEIHIINSPIEWNPVLSGAISFSIQKFLNIEKLKLSSYAKN"
     gene            complement(9518..9997)
                     /locus_tag="ACF3UF_002076"
     CDS             complement(9518..9997)
                     /locus_tag="ACF3UF_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFD3672164.1"
                     /translation="MIKFLRKKKQVELFSPCSGKVIPISEVNDPVFSQKLLGEGFAVI
                     PEEQTIYAPLAGQVTTIFPTKHAISIKSNSGIDYLIHIGIDTVELEGKPFSILVDEKE
                     YITPENPLVKVDFKQLELAKKDSSVIICFTESSQIDNLDLYTGRVLHGVLCGYLNLS"
     gene            complement(10009..11511)
                     /locus_tag="ACF3UF_002077"
     CDS             complement(10009..11511)
                     /locus_tag="ACF3UF_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3672165.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPIL
                     AQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVSYLVYTATI
                     SGFLELFSVKDATLDTGVVGSIAIGGIVAFLHNRYRKIELPQFLGFFGGSRFIPIISS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEHIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTESVAGITVSGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGLAWAIIYFIVFTFFL
                     KKFKVAIPGMIEEKEVVSEINLNKNTSLHEESLMIIKALGCEENIESVEACATRLRVA
                     VKNGQNVDKQAIKQLGATAVFEVKGGIQAVFGGKADLLSQEINQILKRDN"
     gene            complement(11504..12211)
                     /locus_tag="ACF3UF_002078"
     CDS             complement(11504..12211)
                     /locus_tag="ACF3UF_002078"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFD3672166.1"
                     /translation="MKKQIFLDAISGGLIVSCQALPGEPFYKEEGGLMSYFALAAERA
                     GAVGIRANSVRDILEIKEKVSLPMIGIIKRDYPPEEPFITATMREVDELVATGVEVIA
                     LDCTLRKRHDNLSINTFITQIKEKYPEQLLMADISTFEEGKNAYEAGVDFVGTTLCGY
                     TNESRKQEGPAIDLMKQLVQAEICVIAEGKIHTPEQAKKIRELGVSGIVVGGAITRPQ
                     EIAERFVNALKEEEKNV"
     gene            12374..13192
                     /locus_tag="ACF3UF_002079"
     CDS             12374..13192
                     /locus_tag="ACF3UF_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3672167.1"
                     /translation="MNYIYLIKEHYPLLTKSEKKVADLILDSGKAIIYSTMSDIKEKT
                     TVGDATIIRFCQKLGFSGFSDLKIEIAKEDFSKKKEYPSSEKYYDIIATHLTEALYST
                     AHLLDEKKLDKAIQLISQAKNLYIFGVGSSGNTSLDLESMFLRVGVQAKAVLDPHFQA
                     QVASLMEEDDVIIAFSLSGKTKDTFDSVEIAKKNGAKILAITNYLHSPIGQTADVVLQ
                     TAIEEFLNGGSLAGKISQLYLCDLLVQGYEQKNNINAVELRERVLRSILDKSLD"
BASE COUNT         4525 a         2563 c         1929 g         4671 t
ORIGIN      
        1 gcaaattcac tgttatgtcc ttctcttttt ctccaccaag atcgtatctt actgtatagc
       61 catttcttac tccgtctgtt tcgatgccat aatttacttc ttttttaatg ccatcttgtt
      121 cggtaaatgt tacctctcca ttagcgtcta cctgtttctt aagtacttcc gttgatccat
      181 ctgttaaatt tcttaaccgt acttcttttc ccgcttcaag tggtaatcca tttgtgtaat
      241 gtgcttttac ctttaaacta agtggtaact cggatcctgg caaattcact gttatgtcct
      301 tctctttttc tccaccaaga tcgtatctta ctgtatagcc atttcttact ccgtctgttt
      361 cgatgccata atttacttct tttttgatgc catcttgttc ggtaaatatt acctctccgt
      421 tagcgtctac ctgtttctta agtacttccg ttgatccatc tgttaaattt cttaaccgta
      481 cttcttttcc cgcttcaagt ggtaatccat ttgtgtaatg tgctttcacc tttaaattaa
      541 gcggtactat aatttctgct gaatttgtta aactttctgc actggtaatt tgtggggatt
      601 gtagtgaaac gaaagctgtt gtagatagta gcaaaccgcc aagaattatc tttgatttca
      661 taatatcatt ctccttaaat tctatttatt aagctcaaaa aatagttttt atgttaatat
      721 tctagctatt aaaattctta atactacaaa aggaaaccat tgttttattg aatagagaca
      781 tgtccctatc tcctctctaa ttagttttta taaaacgtaa ctattacgtt ttataaaaac
      841 gattttacaa atttacttaa aaaatgtcaa taaaaatgaa ggttcatttt ttattgaagt
      901 gccaaaaata gattaatata aaattcaact cgattttttt cagatagcta aaaatgcaac
      961 ttcagcttta ttagctaaaa agttgcattt tccccgtata ataaatttta tagtctaaag
     1021 catttctaga atttgattgg gagcgtcaat aattttgtgt aaatgattct tccctactgc
     1081 agattgtttc taattctcaa tcagttggct tagcatttgt tcaagttcgc cttcggcctg
     1141 ttgaaagcct ttatgactgc gacctaggaa tttttggttg taagtatcaa aagacgagac
     1201 taagaaacgt tccatcgact cttcgttttg gaactgttcc ttgcggtggc tgtatttctt
     1261 gatttgctta ttaaaggatt caatcaagtt cgtagaataa atactcttgc gtatggccaa
     1321 ggggaaatca tagaaagtga gcaagtgatc gttcgaaaga atcgattcaa ccacttttgg
     1381 atagctggtt ttccattttt ccgcaaaagc accacgtgct tccaacgcca cctctttaga
     1441 tgaggcttga tacaccattt taaaatcatc acagacttcc ttacgatcat cgacacgcac
     1501 tttgtgactg atattacggg aaacgtgtac acaacaatgt tgaaaacgag ctttgggata
     1561 gaaccgacta atcgctccta ccatcccctt taagccatcc gtgatgaaca ggaggacatt
     1621 tttcaaaccg cgctcttgaa ggtccaataa aatttcctcc caaatcgtga tggattcagt
     1681 cggtgcaatc gcatagctca atacttcctt tgatccgtcc gggcgaatgc caactgcgat
     1741 atgaatagct tccttggcga cggttttccg ctttaacgga atatacgttg cgtccatata
     1801 aatagcagca taacggtcat gaagctcccg ccctttaaac gccgttacct cttctgtaaa
     1861 tgattttgtt atattggaca tggtttgggg cgtgtagtaa tgcccataca ttttctcaat
     1921 caagtctgcg atttccgaca tggtaatacc ttttcggaag aggtgaatga cggtctcctc
     1981 taacgtgtca ttcgtccgtc tataagcagg aacagtctgt tgcttgaact caccattgcg
     2041 gtcgcgcgga atctggagat gaagttcccc atactcggtc ttgaccgtac ggtcatagga
     2101 gccgttacga gaattacccg tgttaaaacc aatgcgatca tacttttcgt aatctaggaa
     2161 agccgttaac tccgttttga gaagcgtatt gactgctttc tccaaatgga cacggaataa
     2221 ttcattcaaa tcgcctttgt tcgctagagt ctttagaatt tctgtagtaa aatcgttcat
     2281 agggaagtcc tctcttctgt gaatgtgttg tggtaactct attctacaga agggacttcc
     2341 ttttttctat ttacacaaaa tattttacac tctcatttga ttggacaaca ttcatatata
     2401 tatcaaaaaa actttaacac aactatataa tatttgcata tagatcatat cccaccgctg
     2461 ttaagattgt tacatctaga attagtacct actctggcac taatttccta accgtctcat
     2521 tgaaaatacc acttatactt gaaagcatct tcaatcttag attgtcctcc aaatagtaca
     2581 ctcgaaccat tattgcttta ctatttaact atttggtttt tatagcagtt caagcactag
     2641 ctataccgtg ctattccaaa aagagccctt ttaacattcc tctatttcgc tagtattaat
     2701 tatttaagat tataatgaaa aaaacatatt tcttactatg gcttcgtatc taattttgat
     2761 attatgtaga aaacgaatca tattaatatc gaaaatagat ttccttttgt tttgatttaa
     2821 actttttcaa ttgagattaa cagaactatt cttccttcat tataattact cttctccacc
     2881 atccatctgt atctcaggta ttttaatact acttttacct atttctatta aatgctcagc
     2941 aagtttttct tcattaattt taaagtatga ttctaatacc atccctagat tcattccagt
     3001 tactacttga attcttttat ccatacttgc tttcatcata gctacatttg caggtgttcc
     3061 tcccattagg tctactaata taataatatt tcgtatgtca cttgtttctt ccagtatttt
     3121 attcaattta tttattgttc cttcaatacc gtcattttgt gtcatagaaa ctaccggata
     3181 attaatctgg tttccaagta tcattttagc tgaatttaat atttcctcag ccattaaacc
     3241 atgactcatt aaaattattt cattagtcat cgcacttatt ccccttataa aatatctttt
     3301 aagtaagttt ttttatcgtc tggtgtcata attgtagtaa tttcaacacc aagatttaat
     3361 agcttctcga aggcatttct ttcttcatta gtaacgctaa tattaggacg taaaaccgtt
     3421 gttccttttc gattagacat gttgccaacg ttaatcctat ctatctgtaa atcattttcg
     3481 ataaacgata ataagtctac tggggatttg actattaaaa gcacattttg cccttcatat
     3541 tttccatttt taatattggt aatcgctttc tcctcagtta taattgaaga actgattcct
     3601 gcagggactg ccatccttag cacctgtttt tgtatatcat tatttgcaac agtatcattt
     3661 acaaccatca aacgagtcac acctaattta ttactccaca ttgtagctac ttgaccatga
     3721 attaatcgat cgtcaattct aatatttttt atacccttca tttccacaaa aatttcctcc
     3781 tatcatttat tttaaaatgc ctagagtagc taaaacaata gacagaacca tcacaccaag
     3841 aattaaataa ataggtttta catttttttt caaagaccag taaactaaac caactaaaag
     3901 tgcaggtaat aatcctggca ttatttgatc tagtatttct tgccctctca tagaaaaatc
     3961 accttgttta aaatctaaga cgacatttgt tttaacaaca gatggtatta atgctccaac
     4021 aaccattaat cctaaaattg aagtcgattc agttaaaagt tttaaacttt tttcaatagt
     4081 agtaattaat ttcgtacctg aagtatagcc tatgcgaaat aatggtatac ttatcatctt
     4141 taaagctaca cttacagcaa tccataaaat aattcctact ggactaccat caattgccat
     4201 atttgctgca atagccccaa atatagtcca tggaataact acaaatagac tatcacctaa
     4261 tccagctact ggccccataa gtcctgtctt aatcgatgtc actgcttctt cagtattttc
     4321 atctgaattt tcttccatag ctatattaat acctaaaata tacggtgcaa cccaaggatt
     4381 tgtattgaaa aattgtaaat gatttagtac tgctttttgt aacgcttctg gtttgttttt
     4441 ataagtaact tttaagaatg gtaatacagc gtaacaatat gctagagctt gcatcttttc
     4501 ataatttgaa gaaactgagc ttgtaaaaaa ccatctccat aatacactct ttttaatttt
     4561 ggaattaaca ccaagttttg tcgtctccaa gctattcatc ctcatccata cctcctattg
     4621 tattaacaac ggtattatta attacattct gactattttt tttataaata attaaagcta
     4681 tagcagcgcc tattaatgct actcctaata atggcatttt taagtaaaca gacattacaa
     4741 aaccgataac aagataactg aaatattctt ttgcaggtaa gtatcgaagc aataaaccaa
     4801 taccaacagc tggtaataat cccccagcaa ctgttaaccc atttgttaac cattcaggag
     4861 tatgagcaag aatagtatta attaaagatg gtccaaaaat tactgccaac gcaaccggta
     4921 tgcccgttgt tgccgccgtt aagaatactc caaacatttg catcttggag atcatactat
     4981 aatctcctcg ctttacacct gcttctgctt tatgaaccat ccaaatacca attgtatttc
     5041 taataatatc taattgaacc attaatagtg ctactggtat accaatagaa atccctaccg
     5101 aagattcctg accagttgtt atggtgataa aagttgcgac aatacttgca gtttgatagt
     5161 ctggtataga agctcctcca aaattactaa ttcctaaaga caataattgt aaggttcccc
     5221 caataaaaag cccagttttt atatctccaa gtattaaacc agttacaaat cccgctgtta
     5281 caggttggta ggttccgaac attgttgaat tcttctcaaa attaataaaa aaaccatata
     5341 acacaattaa accaagttga ataacactta tctccattag atctcctcct taattatact
     5401 taatagtttt gaaaatttat ctttttgatt tgtctttata aaaacaggta tcatactaat
     5461 atctgcttca acatccaacg tttgtccgcc atcatattct tcacctgtcc atatattggt
     5521 ccagttttca tttattggta agtaaacttc tcttactgtt tccttataat ttacaatcgg
     5581 tgcaattagg aacgtatctc caaataagta agtatcttct acagcccaag tattattatc
     5641 tgaaggatat tcataaaata gcgtcctcat gatcggatct ccgaatctat gagctttatc
     5701 catcaaagta ctgatatacg gtttcaacgc ttcacgtatt tttatatact tagttaatat
     5761 ctgctcaact tctataccgt atgaccatat ttcatttggt gcaccagtaa ccatcgaacc
     5821 tccaccatga tccgataagg gtttactatg gggtaatcgg tcaccgtgca ttcttaaaat
     5881 tggtgaaaaa gtagcatatt gaaaccaacg aattagcaat tctctaaact ccggatcttc
     5941 tggatttccg ccatgaaacc cacctatgtc agttgtccac cagggaatcc ctgctaaacc
     6001 tacatttagt ccagtattaa cttgatttct aaatgcttca aaactagaat caatatctcc
     6061 agaccacaat aatgcaccga atctttgtgc tccagcccat cctcctctaa caagagtaat
     6121 tacaggctgt tcattactta attcttcata aatcattgaa agataatcga ttggatataa
     6181 attaccacta tataaatcag tccccttttt ataacgataa ttatcaaagt cataaacgga
     6241 atatcctggc tcagctacat ctaaccagaa ataattaatc cctttatcaa cataattctt
     6301 tttaattaga ctccaaacat atttccgagc ttcactattt gtcatatcaa taaaaatagt
     6361 gtttccttga atttgcatgg ttaatcgaac tccacgatta acttttacta gataaccatt
     6421 ttctaaatat ttttcataat tttctgcatc agtttgtact gtaggccaaa ttgagattat
     6481 tggttccact ccgtaatcag ttttcaaagt ctttaaaaat ttttctggat taggccagta
     6541 ttcctcatca aaacaatatt ctccttgctt tggccagtga aaataatcaa tagcgatagt
     6601 tgaaagcttt attccacgtt tatgatactt ttctactaca tccatcactt cctctggtga
     6661 tctatatcgt aatttgctct gccataatcc taataaacta tctggcattt tagggacttt
     6721 tccagttaga ttactatagt ttctaagtat ttcctttggt tcatttcctg aaattattac
     6781 ataatcgata taatcagaag aatacatttt ccatcgagtt atatttttag caaaagaaac
     6841 ttctccaata ccaggattat tccataaaaa accgtatcca agactagata tatagaatgg
     6901 aattgacacc tgtgagtttc tttgcgctaa ttctaaaaca gtgttcttca aatcaagata
     6961 agaatgttga tattgaccca ttccgaatat tttttctttt ggatctgatt caaatctagt
     7021 agttacttga aatttaccat ccatattgga acgatattct cttgacttta atttcaatgt
     7081 agaattaaaa tcctttgtaa cttcaactga accagcatct tcaccaccat catcatgttt
     7141 aacagctctt aatctaatat attcttttag taagacatcg tttttttcat tataaaaagt
     7201 taaacgatca cgatgatcta gtaccgctct tattttcccg ttaattaatt ctgttttatt
     7261 ttcatattga tttattatca ctttatttag ggaattaggc ttatcaatta aggagttttg
     7321 tcgatcttca tagttcatgt ctacaaatga acgtattcta atagcatttt ccccccatgc
     7381 ttcaataatc agtaattcat catcaaattt tcttgaaaaa taatttgatt caatgtttat
     7441 cacttctttc atcccacttt ccttttcttc ttaattagtt aactcttatt acaacactag
     7501 caattgtaat cgcatacata tacatatcaa tttaatttaa gtattttgac tagaattctg
     7561 ctttttaatt tgttttctcg ataaactaat tatcaaaaaa aaaactaata acaaaaaaca
     7621 cttaattact tgaactaaaa ttgtttgtac gttaaactaa ttaataaata aaatataaaa
     7681 taagctattt aaaatgtcaa ctgtaaacgc tatatttttt ttgcataggc tattttattt
     7741 ttaaattgag gagaaattaa tgatttcaag taaatataca attagagaac aaaacgaggc
     7801 aaaaatactt aatcaaataa ttagacataa agaaatatct agagctgaat tgagtaaaat
     7861 aacctcttta aacaaagcat ctgtatcttc tattatcaat aaattgatcg atgactcgct
     7921 tgtaattgaa aatagaattg gagaagcaac aaatcgtggc cgaaaaccca ttatgttaac
     7981 ttttaatgga gtatcttcgg gcttagcaat tgcaattgat ctaggatata attacattga
     8041 tggaatggta gcttcattag atggaaaaga aattgcaaga atacagctta ctgatactta
     8101 tgttagtaaa gacaacatac aaatgttaat tcgtaaaatt ataaaaaaac tcaccgataa
     8161 tcttccttat acgcgacatg gaataatcgg tatgacaatt gctgttcaag gacaagttct
     8221 aaataataaa gtacttagta caacttataa cggtcttgag gaaattgatc tagtaaaatt
     8281 attaaatcaa gagtatagct ttcctgtttt tttacaaaat gaggcaaact tatctgcatt
     8341 aggtgaatat actttttctt ctgatatcga gaatttagta tcaattagtc ttcatagtgg
     8401 aataggcgtt ggagtagtaa aaaatggtaa acttgacatt ggtaataaag gatatgctgg
     8461 tcagttggga catacaattc tatttccaaa tggcagaaaa tgtgaatgtg gtaattatgg
     8521 ttgtttagaa aaatattgct ctactcaagt aatttaccaa gagatttcca aagaaaaaaa
     8581 actagataaa attaattcgg atatagtgga atatctttat agcaacaagg atcaaaaggt
     8641 tgtagagatg attgaactat atgcatacta tttatcgata ggaattaaca atatagttat
     8701 gctctatgct cctgagttag tgatttttaa cagtccttta acaaaaaaaa ttccgaacat
     8761 aattaatata atcaaaaatt ttttgaataa tcaatataca aaagaaattc atatcattaa
     8821 cagtcctata gagtggaatc ctgttcttag tggagcaatt tcgttttcaa ttcaaaaatt
     8881 tttaaatatt gaaaagttga aactcagctc ttatgcaaaa aattaattta atttagtgga
     8941 aactagtatg tgaaatggag aaattttaac atactagacg gctcaccagt actctctcct
     9001 taaaaagagc tttttatata gttatgaatt tctcaccgct ctacctcttt ttcaagagat
     9061 aaaaaaatta atacaatgct tattacttaa actatttcta actcaataat ctatcaaata
     9121 ttctcaattt ttttcaattg tctttttgtt taatcaaagc atgcttgctt attatccatt
     9181 tggcctatac tttagggtaa aattttacaa tttcatctaa attatatact aaacttttat
     9241 cgctattaaa agtaaaaaca gcttcgccca cgtatagaaa cgtatatctt tttgtttcta
     9301 cacgtgggcg agctgactaa aatcatataa tcaaaaactt aataaaacga ggttcactcc
     9361 aatcatattt catttttcaa aactatcaca ttaatctctt gtcaatcaaa attattatac
     9421 attgagaaag ttacaactta tatactactt ctttaaactc taaaacttca ccaatgagtt
     9481 tctaataatt agatcttatt aatctaacta ttaatcatta tgataaattt aaatacccac
     9541 aaagaacacc atgtaaaact cttcctgtat ataaatcgag attatcaatt tgactagatt
     9601 cagtaaaaca aatgattact gatgagtctt ttttagccaa ttcaagctgt ttaaaatcaa
     9661 ccttaactag tggattttca ggtgttatat attctttttc atcaacaaga attgaaaaag
     9721 gttttccttc taattctact gtatctatcc caatatgaat caaataatca attcctgaat
     9781 tactctttat actaatagca tgttttgttg gaaagatagt tgtgacctga ccagctaaag
     9841 gagcataaat tgtctgctct tctggaataa cagcaaaacc ttcccctaat aatttttgtg
     9901 aaaaaactgg atcatttact tctgatatag gaataacttt tcccgaacat ggagaaaata
     9961 gttccacttg ttttttcttt cttaaaaact taatcatata aattcctcct aattatctct
    10021 tttcaaaatt tgattgattt cttgactaag taaatcagct tttcctccaa aaactgcttg
    10081 aatcccacct tttacctcaa aaactgcagt agcacctaat tgttttatag cttgtttgtc
    10141 aacattttgt ccattcttca cagcaacacg caagcgagtt gcacaggctt caacagattc
    10201 aatattctct tcacagccaa gtgcttttat aatcattaaa gattcttcat gcaaagaagt
    10261 atttttattc aagttaattt cagagactac ctctttttct tctatcatac cagggatcgc
    10321 tactttgaat ttttttaaaa agaaagtaaa aacgataaag taaataatag cccaagcaag
    10381 tccaaaagga atcaatttaa gccagttagt tttgtcattt ccttgaagta caccaaataa
    10441 tagaaaatca attagtccac ctgaaaaaga atttcctact cgaatattca ggatatccgc
    10501 aaaataaaaa gataggccgt ctaaaaatgc atggatgaca taaagccatg gagccacaaa
    10561 cagaaacata tattctacag gctcagtgat tcctgttaaa aacgaagtta atgcaccgct
    10621 gaaataaaga ccgccatttt tcttacggtt ttttttagga attgcacgat acatcgcata
    10681 acaagcagca ggaaggccaa acatcatcgt ggcaaatctt ccagcaaaaa aacgagtccc
    10741 ataagtaaat aagcctgtgt gattcggatc agctaattga gcaaagaaaa tattttgtgc
    10801 cccagaaact gtaattcccg ctacactctc agttccccct aacgaagtgt accagaaaag
    10861 tggataaatt gtatgatgaa gaccaacagc accagttaaa cgaagtaaaa atccataaag
    10921 aaatgttcct agactcccca tttgagcaat atgctctcca gcaacaacta atccattctg
    10981 aatcggtggc caaattagat aaaagaagga accaataata attgcagcca aactagaaat
    11041 aattggaata aaacgtgaac caccaaagaa tcctaaaaac tgcggtaatt ctatttttct
    11101 atagcgattg tgtaaaaatg cgacaattcc gccaatggca attgaaccta caactccagt
    11161 atcaagagtt gcatctttga cagaaaataa ttcaagaaaa ccactaattg ttgctgtata
    11221 aactaagtaa gaaacaccac cagctaaacc agcagttcct ttgtcaccat ttgcaagccc
    11281 cactgcgata ccaatcgcaa atatcaatgc taaattagca aaaacggcgt taccagcata
    11341 actcatgata ctcaaaatcg tatgaagcca cggttgagct aatatgggat aagcatttat
    11401 ggcgctttca tttgtcagtg caccgccaag acctaaaagt aaaccagcaa caggtaaaat
    11461 agcgatcggc aacataaatg cccgacctag ttgtgaaaat tttttaaaca tttttctctt
    11521 cctccttcaa tgcattgacg aaacgttctg caatttcttg tggacgagtg atcgcgccac
    11581 caactacgat tccagaaaca cctaattccc taattttttt tgcctgctct ggggtatgga
    11641 tttttccttc tgcaataaca caaatttctg cttgaacgag ctgtttcatc aagtcaatcg
    11701 ctggcccttc ttgctttcta ctttcattag tatatccgca taacgtggtt ccgacaaaat
    11761 caacgccagc ttcataggca tttttacctt cttcaaaggt agagatgtct gccattaata
    11821 attgttcagg atacttttct ttgatctgag taatgaaagt gttgatagac aaattatcat
    11881 ggcgtttgcg cagcgtacaa tctagcgcaa taacttctac accagtagca actaattcat
    11941 cgacctcacg catcgttgcg gtaataaatg gttcttcagg aggataatct cgcttaatta
    12001 tcccaatcat aggtagagaa actttttctt taatctctaa aatatctcga acagaatttg
    12061 ctcggatacc aactgcacca gctctttcag cagctagagc aaaataggac ataagacctc
    12121 cttcttcttt ataaaatggt tcaccaggta atgcctgaca agaaacaatc agtccacctg
    12181 aaattgcatc taaaaatatt tgtttcttca ttctcctaaa cactccactt taaattaatt
    12241 ttcggataat aactccaaat aaaatatagc acgcgctttc attgatgtaa agtataaaaa
    12301 tggataaatt tggagatttt tttatctttt tggagtataa tggagtaaaa ttttttactg
    12361 taaaggagtt catatgaatt acatctattt aattaaagag cattatcctt tattgactaa
    12421 atctgaaaaa aaagtagctg atttaatctt agattctggg aaagcaatta tttatagtac
    12481 aatgagcgat atcaaagaaa aaaccacagt tggggatgca acgattattc gtttttgcca
    12541 aaaattagga ttttctggtt tctctgattt gaagatcgaa attgcaaaag aagatttcag
    12601 taaaaaaaaa gaatatccgt caagcgagaa atattacgat ataattgcta ctcatctaac
    12661 tgaggcgctc tattctacag cacatttact agatgaaaaa aaactagata aggcaatcca
    12721 actcatcagt caagcaaaaa atctttatat atttggggtg ggttctagtg gaaatacaag
    12781 ccttgattta gaaagtatgt tcttacgagt aggagttcaa gcaaaagctg ttctggatcc
    12841 tcattttcaa gctcaagtag cttctttgat ggaagaagac gatgtgatta ttgctttttc
    12901 attatccgga aaaacaaaag atacctttga ttctgtagaa attgcaaaaa aaaatggtgc
    12961 aaagatctta gcaattacca attaccttca ttctccaata ggacagacag cagatgttgt
    13021 tttacaaaca gcaatcgaag aatttttaaa tggtggttct ttggcaggga aaatctctca
    13081 attgtacctt tgtgatttac ttgtacaagg ttatgaacag aaaaacaata ttaatgcagt
    13141 ggaattacgt gaaagagtat tacgctctat cttagataaa agcttagatt aaatagagta
    13201 ttaattgaag caatttatat ttaggtgaaa tatcaattaa ttagtgggac tcacaatttg
    13261 cacaaataac tttcatctta cctttagatg aagtgttaga aagaaaagta tcaaccatca
    13321 atactttgaa aaaattcttt ttataggaat atgatgaaca gctttcaata tacaataatc
    13381 attatcaaag ataactgaca acttttagca ataaaataca aaacactttt ttagtcagta
    13441 tctaaatata acaaatctat ttcataaagc aaaaaagcgg ctagacaaaa gagatgtcta
    13501 accacttaca tttatcatct atataattca atgaacagag aaaaaaagga catcagtttt
    13561 tatcaataaa aagtcttgtt cttatcaata ttttcagatg ttttagcaga tcctcttcaa
    13621 attctataga ttgtttatct tgttgatata aagatagata aagcaataat ttttttcgat
    13681 aaaataca
//
LOCUS       DAXLPY010000062        13428 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.062, whole genome shotgun sequence.
ACCESSION   DAXLPY010000062 DAXLPY010000000
VERSION     DAXLPY010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.062"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..306
                     /locus_tag="ACF3UF_002080"
     CDS             <1..306
                     /locus_tag="ACF3UF_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3672168.1"
                     /translation="HFARREKKLYRSLYLEEYGGGKEMQNFSYTYFVNTVKRDPAYVN
                     LSEEQIESLYNGTWIIATGIAALMSSSIIHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(484..924)
                     /locus_tag="ACF3UF_002081"
     CDS             complement(484..924)
                     /locus_tag="ACF3UF_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFD3672169.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLSGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            1082..1846
                     /gene="map"
                     /locus_tag="ACF3UF_002082"
     CDS             1082..1846
                     /gene="map"
                     /locus_tag="ACF3UF_002082"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFD3672170.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            1878..2801
                     /locus_tag="ACF3UF_002083"
     CDS             1878..2801
                     /locus_tag="ACF3UF_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFD3672171.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            2877..4016
                     /locus_tag="ACF3UF_002084"
     CDS             2877..4016
                     /locus_tag="ACF3UF_002084"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFD3672172.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            4009..4809
                     /locus_tag="ACF3UF_002085"
     CDS             4009..4809
                     /locus_tag="ACF3UF_002085"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3672173.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            4809..5636
                     /locus_tag="ACF3UF_002086"
     CDS             4809..5636
                     /locus_tag="ACF3UF_002086"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3672174.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            5641..6348
                     /locus_tag="ACF3UF_002087"
     CDS             5641..6348
                     /locus_tag="ACF3UF_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3672175.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            6448..7314
                     /gene="rfbA"
                     /locus_tag="ACF3UF_002088"
     CDS             6448..7314
                     /gene="rfbA"
                     /locus_tag="ACF3UF_002088"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFD3672176.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            7328..7900
                     /gene="rfbC"
                     /locus_tag="ACF3UF_002089"
     CDS             7328..7900
                     /gene="rfbC"
                     /locus_tag="ACF3UF_002089"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFD3672177.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            7922..8950
                     /gene="rfbB"
                     /locus_tag="ACF3UF_002090"
     CDS             7922..8950
                     /gene="rfbB"
                     /locus_tag="ACF3UF_002090"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFD3672178.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            9048..9899
                     /gene="rfbD"
                     /locus_tag="ACF3UF_002091"
     CDS             9048..9899
                     /gene="rfbD"
                     /locus_tag="ACF3UF_002091"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFD3672179.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            9933..11966
                     /locus_tag="ACF3UF_002092"
     CDS             9933..11966
                     /locus_tag="ACF3UF_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672180.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPAKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKIDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKEIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            12010..13290
                     /locus_tag="ACF3UF_002093"
     CDS             12010..13290
                     /locus_tag="ACF3UF_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFD3672181.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVCTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIATLLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
BASE COUNT         4120 a         2269 c         2844 g         4195 t
ORIGIN      
        1 cattttgcaa gaagagagaa gaagttgtat cgttcactgt acttagaaga atatggtgga
       61 ggaaaagaga tgcagaattt ctcttatact tactttgtga atacagtgaa acgcgatcca
      121 gcttatgtga atctttcaga agagcagatc gaatctttgt ataatgggac atggatcata
      181 gctactggga tcgcagcttt gatgtcttca agcatcatcc atccaactga tgaacagatt
      241 gaaaagatga tacaagacag tatagatgct atcttgaaat tcaaagaacc aatagaaatc
      301 gattgaatat actcaaaagt tccacaaatc agtagataac aagagatgtg tcaaaataag
      361 gaaaagttcg tttttcttac agcgtatgca tttttaactc ccgaagaact cttccatgaa
      421 tgcaatgaat aaaagagccg tacagattga ataaatctgg atggctcttt tattgcaagt
      481 atattaaatt tttgcgacta gttctttagc gaaagcttct aaattttcga tatcttcttc
      541 ttcagcattc agatccactt taacattttc ggctcctttt gatgcgcctg tttttgcaaa
      601 agcagcatcg aaatcatcca ccgatttgca gaattcatcg taaaaagtat caccagatcc
      661 gcagacaccg taaatttttc ccgatagatc caattcttgc aagtcttcat aaaagtctac
      721 gatctcatca ggcagatcgc catcatcgta tgtataagta gctactacgc aaatatctgc
      781 ctcctcgaat tcatctgcat ctacttgggt acattcgttg atttcgactt cgatatccag
      841 attttcaaat gcttctgcaa caatatcggc gatttcttca gtgtttcctg tcatgctagc
      901 atatacgatt tttgctaaag ccatgatgtg cctcctcgtt tataattatt taacaattat
      961 gaattatacc aaaacatcat tgaaaagaaa ataaaaccta gagacacctg gggaatgtca
     1021 tttggctaaa tgtatgccgc tatgttaaaa tgagagggat ttgtaaaaag gagacgaaaa
     1081 tatgattact ttaaaatcag cacgtgaaat tgaaatgatg gcagaatctg gagctttatt
     1141 agcagatgta cataaaaatc tgcgtgattt tataaaacca ggaatcacaa gttgggatat
     1201 tgaggtattt gtcagaaact atatcgagag tcatggcgga attgctgcgc aaattggctt
     1261 tgaagggtat gaatatgcga cttgtatcag tataaatgat gaaatttgtc atggattccc
     1321 tcgtaaaaag cctttgaaaa acggtgattt ggtaaaagtc gatatgtgta tcgatttgaa
     1381 aggcggcatt tctgattctt gttgggccta tgtagttgga gaatctacac ctgagatcga
     1441 ccgattgatg gaagtaacga agaaagcttt gtacatcggt attgagcaag cacaagtagg
     1501 gaatcggatt ggtgacatcg gtcatgctat ccaaacttat gtagaaggcg aaaatctagc
     1561 gatcgttcgt gattttattg gtcatggcgt tggtcctacg attcatgaag aaccagcagt
     1621 tcctcattac ggagaagctg gaaaagggtt gcggttgaaa gaaggcatgg ttatcacgat
     1681 cgaacctatg gttaataccg gaacttggaa aatgaaaatg gatcctaacg gctggactgc
     1741 gtatacaaga gacggcggac tttcttgcca atatgaacat acattggcta ttactaaaga
     1801 tggtccaaga attttgacat cacaaggaga agaaggcact tattgatcta tccagtcaat
     1861 aggtacggga gaggtacatg aaagtttgga acaaaataaa acaaaatgaa aatctgatgc
     1921 gctttattga gacgactcaa aagcgcatca ctgattcaga aatgagtacg acctctgtcg
     1981 tcgttgctta ttatttactc ttgtctttat ttccattgat tattgctttt ggtaatattt
     2041 taccgtttct ccacatcgat caagagactg tactgaccta tttacgagaa gtgattcctg
     2101 agaccgttta ccagtttatc ggtcctgcaa tcaaagacct tttgacacaa agttcaggag
     2161 gcttgttatc cgtttctgca ttagcggctt tatggtctgc aagtcaaagt atcaatgctt
     2221 tgcaaattgc gatgaataaa gcgtatggcg tagaaaatag aaaaaatttt ttgatcgtcc
     2281 gtttcttctc actaattgtc attgtcttgt tcatgattgc tattagtggg gtaactatcg
     2341 ttcttgggtt gggacagctg attttggatg ctattcagcc aatcgtacaa atacccgtga
     2401 actttatcga tcagttccaa actttgaagt ggccaatcac attggtagct ttatttgtca
     2461 tcatgttctt gatttattta attgtcccta atgctcagtt gaagttgaag acgatcattc
     2521 cgggcacgat cttcgctact gtcggctgga tgctgttatc acaagtgttt agtatctatg
     2581 ctaggtattt tgcaacgagg atcagcggtt atcagatcat aggaagtttt attgtactca
     2641 tgctttggct taattttgct gctacgatca tcattttggg cggaatcatc aatgcagttg
     2701 ttcaagaata cgtgacgggt catcaaatca aaaaacgtcg agatccaagc cgaaaatggt
     2761 tcaataaatt gaaaactaaa ttttctcata aaaaaaagta gaaacaagag ttcttattgt
     2821 aaatttatat cagtaattta taataattat gactcttaat taaagtaggt gcccatatgc
     2881 ttgtttcttt tagtatggtt ataagatttt ttctgacaat tttattatca ctgatattaa
     2941 cacctgtatt caaaatcatt tcagtacaaa caggtatggt cgacaaacca aatgaaagaa
     3001 gaataaataa agttccaatg ccttcagcgg gcggactgcc tatctttatt tcatttgtta
     3061 tatcgacttt attcttattc cgtaaaatta tccctcaatc gtatattgta ccgatcttga
     3121 ttgcttcttt agtaatcata gtcacaggag tgctcgatga taaatatgag ctgacaccta
     3181 aacaaaaaag tatagggatc ttgattgctt ctcttattat ttattttgta gcagatatac
     3241 gtattgattc cttcacgctt ccttttattg gatatatcca actaggctgg cttagttttc
     3301 ccgtaacgat tttttggatc ttcggtatca cgaatgcggt caatctgatt gacggtttgg
     3361 atgggctggc ggcagggatt tcattgatcg gtttaattac gataggaatc attggatatt
     3421 ttttcctcca tgcttctaca gtgtatattc cagttgttat tttctgtctt gtagcaagta
     3481 ttatcggttt ttttccttac aatttttatc cggcaaagat ttatttaggc gatacaggag
     3541 ctctattcct agggtttatg atggccgtcc tttcactaca agggctgaag aacgtgactt
     3601 ttgtttcatc gatttctttg ctgatcgtca tgggagtgcc ggtaacagac acgttttttg
     3661 ctatcattag gagaaaagca aaccgtgttt ctttttctac agcagataaa aaacatcttc
     3721 atcaccgact aatcagttta ggctttactc ataaaggtgc tgtcctgacg atttatgcga
     3781 tggctttgat gttttctttc acagctatgg tcatgaatta tactggaaga atcggaacga
     3841 tcatattgat tattgccatg ttgtttgctg caattttatt atttgaattg attggtctga
     3901 tcaatgagaa acatcagttt attttaaaaa cattgcgatt tttagggaat aaagagtacc
     3961 gtacgcaagt aaaacagaaa tatttgaaga aatggaaccg tcatatagat gaataacaaa
     4021 ttaaaccagc cgatccttat tagtattgtg acggcaaaca gtgataaaat ttttcggaca
     4081 ctagataatt ttatttcaac tgtaaaagat gaaacagcag taaaaatccg aatttttgac
     4141 aacaattcac ttcccgagta caaaaaaaga ctaacagagt ataggaaata tccctacatc
     4201 gatatctatt ttcatgatga aaattccgga tttggttatg gacataatca caatctgata
     4261 gctagcgatt ctcgctatgg cattatttgt aacccagata ttttagtgga tgaagagaca
     4321 gttacagcat tggtcttgtt attgaaagaa catccggaat gtgcgatgtt agcacctaag
     4381 attcttaatg aagatggaac aactcagcac ctcatccgtg agcagctggc tgtttttgat
     4441 tacgttttgc gctttgtgcc tttcaaatgg gtcaaaaaaa agtttgacaa acgactggct
     4501 gtgtttgaat gccgaggatt gcctactgat gctaatagtt atgtacggat gatctcaggt
     4561 agttttatgg tagctgatat tgataaattt aaagagataa aggggtttga tgagcgtttc
     4621 ttcatgtact ttgaagacaa cgacttgtgt ttgagttttg aaaaagcagg ttacaagtta
     4681 ttgtacacac ccttttatgc agttatccat ttttacggga agggtgcgca tcgaaatgca
     4741 aaactgtttc gcgtgttttt gacttctatg atgaaatttt tcaataagtg ggggtggcgt
     4801 tttttctgat gaaaccagaa atattagtag tcgttgtgct ttatcagcaa ctattcagtc
     4861 aatctccagc ttatggacca ttaagcaaag cacttagcga aaagcaaatt cagcttatta
     4921 tttacgataa tagtcctcaa aggcagcaaa atgagctgtt tgaaaaagaa aatatcgttt
     4981 atcatcatga tccgcaaaat cctggtttag cggtggctta taattttgcg ttgtctcaag
     5041 cagatgaagg aacacgttgt ctcgtcactc tggatcagga tacgaggcta gtcgacgatt
     5101 attttgaact attgcgtaaa gtaaccttta cagatgaatg tgttgctgca gttccgatga
     5161 ttttttctgg gagccgacaa gtttctcccc tatattcaga tcgttatatc aatcgtacag
     5221 ctcaagcagt agaagttgaa ggcccaacag ctgaacgaat catggcaatc aattcaggtg
     5281 ttgcctggtc tgtcaaattt ctaaaaaaga ttggcgggtt taatcctgct ttttctttag
     5341 attttttgga tcattggctg ttttggaaag tggatcagtt ggaaaaaact gtggagatcc
     5401 ttcctgtacg aatggaacat gatctttcgg ttttagacta tgaaaaagtt tcaagtaatc
     5461 gataccgttc tattttacaa gcagaaaatc gattttatca tgaatatgat caaaggcatt
     5521 tatccagtca ccgacgacaa ttattgttaa gaacagctaa acagttcttg accgtcaaaa
     5581 accggcatat ctggcggatg actttgcgct catatgttaa gaattggaag gtgtgaattc
     5641 gtgcgttcgg tttgtatagc tacctttaat ggaggcagat atttaagaga gcagttagat
     5701 agtattttat ctcagctttc agcagaagat gaagtagtca tttctgatga tgggtcagta
     5761 gatgatacat gggatatatt aactgaatac gcagaaaaag ataagcgaat ccagcttttt
     5821 tcggggcctc gtcaaggatt gatcgctaat tttggttatg cgatccagca gacgaaagga
     5881 gatctaatct ttttggcaga ccaagatgat gtttggttgg agacaaaagt gaaaaagatc
     5941 actgactatt ttgagcagaa tccggatcag ctagtagtag tttctgattt aatcattgtg
     6001 gacagcgagc tgcaagagat ccatgattcg tatttttcgt ttcgaaattc caaagaagga
     6061 tggcttaata atgtgataag aagtcactat attggtgctg gtatggcttt ccggtcttct
     6121 ttaaaacccg atattttgcc gatcccgtca gaagtgccga tgcatgatat gtggattggt
     6181 ttgctgggag gaaagaagac tgggttccta agagaaccgt taactctgta ccgaagacat
     6241 gatttaaacg cgagtgagat tgaaacacat tctaaattac ggcaaaaaat ttcttggcgt
     6301 gttcatctga ttacggcgtt gatcaaacga aaatggttta aacgttgata aaagatgttt
     6361 aaatccttaa tatttccatg acaaatataa caattgatga gataataaca aagtgaaatt
     6421 tgaaatcaaa aaggagagca gatatccatg aagggaatca ttcttgctgg gggcagcgga
     6481 acacgtctgt accctttaac aaaggcaaca tcgaaacaat tgatgccgat ttatgacaaa
     6541 ccaatgattt attatccaat gtctactctg atgttggcgg gaatcaaaga aattctgatt
     6601 atttcaacgc cacaagatac accacgtttc aaggaattat ttggaaacgg aaatgattta
     6661 ggactgcaga tcgaatatgc agtacaagaa agtccagatg gattggcaca agcgtttatc
     6721 attggagaag aatttattgg agatgatagt gtctgcttgg tattagggga caatatttac
     6781 tatggtggcg gtctgtctaa aatgttgcaa cgagcagctt caaaagatac aggcgcgaca
     6841 gtatttggct atcatgtcaa tgatccagaa cgctttggtg tagtagaatt tgatgagaat
     6901 atgcaagctt tgtcgattga agaaaagcct gctcagccaa aatcaaatta cgctgtaact
     6961 ggcctttatt tttatgacaa tgaggtaatt tctatcgcta aaggtatcaa accttcagaa
     7021 cgtggagaac tagagattac ggatgtcaat aaagcatatt tggataaagg aaaactatcc
     7081 gtagaactta tgggacgcgg atttgcttgg cttgatacag gaacacatga atcattgctt
     7141 gaagcatcta cctttatcga aacaattgaa aaacgtcaga acttaaaagt ggcttgtttg
     7201 gaagaaattg cttaccgtat gggctacatc gataaggaac aattgctggc ccttgcacag
     7261 ccattgaaaa aaaatcaata cggtcaatat ttattgaatt tggccgctga ataaggagtc
     7321 cttacagatg aaagtaacag atacaaaatt aacagatgtc aaaatcgtag aaatggacgt
     7381 ctttggcgat catcgcggtt tcttcacaga aagttattca aaagcaaaat ttgcagaaca
     7441 tggattgaaa tatgactttg ttcaagacaa ccattcacta tcagctgaag ctggtgtcct
     7501 tcgggggctt catttccaaa aaggagaagc tgcacagaca aaattgattc gggtagtcac
     7561 tggagcagtt ttagatgtag tagtggatat ccgcaaaggt agcccgactt atggtcaatg
     7621 ggacggattt atcttatctg aacataatca tcgacagttg cttgtaccta aaggatatgc
     7681 ccatggattc gttactttga caccaaatgt gaacttcctt tataagtgtg ataattacta
     7741 taatgcagaa gcagatgggg gcatcgcatt tgatgatcca gatttagcga ttgattggcc
     7801 aattgatcca tcaagagcga ttatgtcgga aaaagatcac cgtcatccga cattaaaaga
     7861 atttgaagca gaaaatccat ttgtttacgg agaaatctaa gaattaagga gaaattttct
     7921 tatgaaaaac atcattgtta ccggaggtgc cggattcatc ggctctaatt tcgttcatta
     7981 cgtggtaaac aatcatccag aagtgcatgt cactgttttg gataaactga cttatgcagg
     8041 aaacaaagag aacttggctg gacttcctag cgatcgcgta gaattggtcg taggagatgt
     8101 tgcagatgca gaattagtgg accgtctagt aaaagaagcg gacgcagttg ttcattacgc
     8161 ggcagaatcc cataacgata attcattaaa agatcctttc ccatttgtac aaacgaatat
     8221 cattggtacg tatacacttt tagaagcttg ccgcaagtat gatgtacgct atcatcacgt
     8281 atctactgac gaggtttacg gcgatcttcc attacgtgaa gacctgccag gacatgggga
     8341 aggcgaagga gaaaaattca ctgcggaaac accatataat ccttcaagtc catattcttc
     8401 tacaaaagct ggttcagatc tgttagtaaa agcatgggtg cgttcttttg gcttacgtgc
     8461 aaccatttca aactgttcaa acaactatgg tccttatcag catattgaaa aatttattcc
     8521 tcgccaagta acgaatatct taagcggtat tcgtccaaaa ttatatggcg aaggaaagaa
     8581 tgttcgtgac tggatccata cgaatgatca ttcttcagca gtgtggctga ttttgacgaa
     8641 aggcagaatt ggcgaaacct atctgatcgg tgcagacggt gaagaagata ataagaccgt
     8701 gatggaattg atcttagaaa tgatgggtca accaaaagat gcgtacgacc atgtaaacga
     8761 ccgtgcagga cacgacttgc gttatgcaat cgattcgaca aaattacggg aagagttagg
     8821 atggaagcct gagtttacga acttccgtga tgggttggct gacacgatca aatggtacga
     8881 agaacatgaa gactggtgga aaaaagaaaa agaggccgtt gaagcagcat atgccaaaaa
     8941 tggacaataa tacagagaaa atgtcactgt attaatggaa aaacacatgt gaggcaggcg
     9001 ctcgcctgtc tcttttttaa aataaaaatc aaggagcgga taatcatatg tttttattaa
     9061 ctggaggaaa tgggcaacta ggtacagaat tgcgccattt attagatgaa aaaaatctgc
     9121 aatatgtttc aacagatgca aaagacttgg atatcacaga tgccgagaaa acaatggctt
     9181 acatcacaga attaaaacct gatgttattt tccattgtgc agcttacaca gcagtagata
     9241 aagcagaaga agaagcaaaa gaattagatg agaagatcaa tgttgatggt acaagaaatg
     9301 tagcacttgc agcaaaagct gtgaatgctc aattcgtcta tatcagtaca gactatgttt
     9361 tcgatggaaa aaacaaaaat gtagaatacg aagtagacga ccaaacgaat ccactaaatg
     9421 aatatggtcg tacgaaatta ttaggcgaaa aagcagtaga agagatttta gaagactatt
     9481 atatcatacg aacttcttgg gttttcggga tctatggaca caatttcgtc ttcacgatgc
     9541 aacgcctagc ggaaacccgc gacaaactga ctgtagtaaa tgaccagttt gggcgaccaa
     9601 cttggacacg tactttggca gaatttatgg tatatgtcat cgaagaaaaa gcaccatttg
     9661 gtatttatca tttgtcgaac gaaaatagct gttcttggta tgaattcgca aaagaaatat
     9721 tgaaagatac agatgtagaa gttgcacctg ttacgtcaga agaatttccg caaaaagcaa
     9781 cacgtccgca gtattcagtc atgagcctga aaaagacaga agagttagga tttgtcatac
     9841 caacttggca agaagcactt gcgcaaatgc tggaagctgc caaaaaaatg aataagtaat
     9901 ttccttttat caaatagaat ttggagcatg atatggaaaa acaaacaaga agtgcacgac
     9961 gaaaagaaaa gccaaaagcg aaccaggcag attcgaattt ggtgcttgac ctgtttctaa
    10021 aactccgcta tcttattggc gttttagtca tcgtggtcat cgttactttt aatttaaacg
    10081 gaagttcact tggtgtttgg gataaatatg tgtcgcaaag agacgatggg aaaaaaactg
    10141 atgtgatttt tggacagaat cgggaagtgc ggtcagacga atggctggtg cagacacctt
    10201 tttacctctc acaagctgaa gaggactttc cgttggtgaa cgaggattat tcattaaacg
    10261 gacaaaacat gatcattgcg tataattctc ctgcaaagga tattacggtt atcggaaaac
    10321 cattcaactg gggattcttt ttcctcggaa gagatcgagg actttccttt tattgggcga
    10381 tgaaattagt cgtcatggtc ttgcttggat tcgaagtact gatgatatta acgaagagaa
    10441 aaaaagctct atcgctaatc ggtgcatttg cgctgacatt ttctccagca gtccagtggt
    10501 ggttcatgca acatgtgggc gatttgattt tctttacttt gggactgatg actgcttttt
    10561 atcattattt ctacaatcat gataaaaaat ggctacgaac gttgatgatg cttttggtgg
    10621 ttattttcgg tattgggttt attttagtga tttacccagc ccatcaagtg atgctggcgt
    10681 acttgctgat tttttatttt gttggcctgc ttatttacta tagcaagaaa gtttcatggg
    10741 atctgttgga tgtagtgttg attggagggg cagttttatt tattggcgga gtcatggttc
    10801 atttctggct aacgtcaaaa gacgcattgt tagcttcttt gaatacctta tatccaggaa
    10861 aacgggtaag tactggagga aagtggacga ttggcgaatt tttttctttc cttacaaatt
    10921 ggaaaattcc ttttgaagat atcaactatt cgaataactc tgaagtggcc ctgttctatc
    10981 acttttttcc aactgtattc ctagcaagtc catttgtgtt atttggcaaa aaagatagcg
    11041 aacaaaagtt actgggacgt attttgatga ttttttgtct gttttctatc ttttggatta
    11101 ccgttgggtt gccaaaatgg ctagcagaaa tcactctgct gtcttatgtt cctccattaa
    11161 gagccatcct tacttttagt tttgcggctt gtttattatc gatctggttt atcgcttata
    11221 tttggagaga agatgttatt cctatttggt ataaattcat tttgttggca gtaaatgcat
    11281 ggtcttattt ctatgcgatt acgcattcga aaatagataa ttatttttcg gattttgaaa
    11341 ccatcgcagt tgctgtgttg ggaacagtga ttttagcatt tgcattattt ggctggagac
    11401 gcttgtttta cctcgctttt gccgccttag ttatcgtatc tggctttttc gtcaatccag
    11461 tcgtagaagg tacaggagcg atttttgaaa aaacactggc aaaagaaatc caaaaaatcg
    11521 atcaacaaga tcctggtaaa gtttggttgt ctgaagatga attatataac ttcaccccaa
    11581 cattgggagt gaaatccttc aatacagtac gcttttatcc agatatagct gcatggaagg
    11641 aaatcgatcc gaaagaagaa tacgagaagt attataatcg gtatgctcat acaagagctt
    11701 ttatcgctaa ggaagataca aagttcattt tagatcgtcc agatatgttt tcggtcacgt
    11761 tgaattttga agacgcagaa aaattaggga tcgactatgt gatcagtaaa cgaccattaa
    11821 ctgattacaa ccaattatat gaagcgcagt tcacgcagct atatggaccg gataaagacg
    11881 gttatatgat ttttaaagta gaatatccgg attatccaga tgtaccacaa acacaaactc
    11941 aggaaaatca gctagtcgta cagtaatagg ctagctgaga ataatcctga aatattagta
    12001 gaaaggagag tggagataat tcaagcaatc gtacaaaaat ttgtcaacaa aatgagtgtc
    12061 ggtttcttgc ttttgttgct gacgctagtc ttttttgttt gtacagcagg gttaggtttt
    12121 ccagcaactt tgtttatata taacaatagt tcattactta tcgcttttag tgtggctatt
    12181 ttgctcattt taaatgttta taaagcaaaa ggcgtcgatt ttctttatct aggtgttgcg
    12241 cttgcccttt tcattttctt ttcttacttt cgggaattaa gaaatgagtc tttatttgga
    12301 gatttactgt ttcctttgat tattttattt tgtttagtaa ttaaatggat cgagtggaca
    12361 aaatgggatc gcggtattta tctgattgtc tttacggtct tcctcggaat cacgttatat
    12421 cgtgtattta cagagatcca agtaccagaa ggacaaagca tctgggctcc aggcaattcg
    12481 ctttctgata tttggatcaa tacgaataca atcggaagtt ctttgatgac tcttgcttta
    12541 ttgatcagtg gatttgccag ttcttttgaa cgatggtatg tacgaatcat cggtgcagta
    12601 gcagttgttg cagcttttct cgggatttgg gtctgccaat ctagaggtgc attagtcgcg
    12661 ttgattgttt ttgcgatatt ggatctttta cctaaatcgt tgatgcgtgt cattcgtgcg
    12721 ccatttattg cttacacggt tacgattctt ttagctttgc cgatttctta tctggcggct
    12781 gtctctgaaa aagtcaattt gtttaccggt cgagaagata tttggcataa attctatcag
    12841 acgctaggag aaaaatctga acaagtttta ctaggaatga aaacatttat cttccaacga
    12901 ggaaaccaat ttttaggaaa ccacaatagt tataattcta ttttgaatat ctatggattg
    12961 ataggatttg ggattgctac tttgctgctt atccttttta ttggtcgctt aacgttgaaa
    13021 gcagatttat ccaacgggca gatgactttt atctgggcct tttttgcggt gatgatgcag
    13081 tcatttatgg aggatacatt gacttcatac ccatgggttc cgattattta tatcctgttg
    13141 gctatggccg ttcatcgata tgatgaacca gaagttgcgg aggaattcta tgttatggaa
    13201 gaggcatatg acgatatgac ttatgatgat acatcttatg aggaacaacc agatagcgct
    13261 cattcttcca ggatccaacg ctatcattga taggcacaaa atacggctct ttgtcaataa
    13321 ggactgatgg gttgtacaaa atcaaatctg ggtcagaatg aacctcattc tggctcagat
    13381 tttttgttat cttactttga ttaattgatt gatcaaaaag attctaat
//
LOCUS       DAXLPY010000063        13279 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.063, whole genome shotgun sequence.
ACCESSION   DAXLPY010000063 DAXLPY010000000
VERSION     DAXLPY010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.063"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..3044)
                     /locus_tag="ACF3UF_002094"
     CDS             complement(<1..3044)
                     /locus_tag="ACF3UF_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFD3672182.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPE
                     DKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVT
                     FTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEF
                     VSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVS
                     AAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
     gene            complement(3661..4095)
                     /locus_tag="ACF3UF_002095"
     CDS             complement(3661..4095)
                     /locus_tag="ACF3UF_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672183.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(4112..5317)
                     /locus_tag="ACF3UF_002096"
     CDS             complement(4112..5317)
                     /locus_tag="ACF3UF_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFD3672184.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            6011..6397
                     /locus_tag="ACF3UF_002097"
     CDS             6011..6397
                     /locus_tag="ACF3UF_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFD3672185.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            6491..6682
                     /locus_tag="ACF3UF_002098"
     CDS             6491..6682
                     /locus_tag="ACF3UF_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672186.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            7196..7528
                     /locus_tag="ACF3UF_002099"
     CDS             7196..7528
                     /locus_tag="ACF3UF_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3672187.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7438..7632
                     /locus_tag="ACF3UF_002100"
     CDS             7438..7632
                     /locus_tag="ACF3UF_002100"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3672188.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            7671..7817
                     /locus_tag="ACF3UF_002101"
     CDS             7671..7817
                     /locus_tag="ACF3UF_002101"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672189.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            8255..9595
                     /locus_tag="ACF3UF_002102"
                     /pseudo
     CDS             8255..9595
                     /locus_tag="ACF3UF_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9836..11452)
                     /locus_tag="ACF3UF_002103"
     CDS             complement(9836..11452)
                     /locus_tag="ACF3UF_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFD3672190.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            11570..11788
                     /locus_tag="ACF3UF_002104"
     CDS             11570..11788
                     /locus_tag="ACF3UF_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672191.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11983..12444
                     /locus_tag="ACF3UF_002105"
     CDS             11983..12444
                     /locus_tag="ACF3UF_002105"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3672192.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(12637..12876)
                     /locus_tag="ACF3UF_002106"
     CDS             complement(12637..12876)
                     /locus_tag="ACF3UF_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672193.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12900..>13279)
                     /locus_tag="ACF3UF_002107"
     CDS             complement(12900..>13279)
                     /locus_tag="ACF3UF_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HFD3672194.1"
                     /translation="EYKDYYTTGYKTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKI
                     LNYEKGNRGVRFNFETDDAGAGRFKYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEL
                     HNWPTFYPASLSKHEIAQEMMAH"
BASE COUNT         4280 a         2499 c         2031 g         4469 t
ORIGIN      
        1 ccttctactg ttggctcata tttatcggcg tcagaacgat tgtctgtcac tgtaacatct
       61 acttcaactt catcagatga tccatctgga tatgtcacta caacagtccc ttttttattt
      121 ccagctgcgc taacatctac tttttctttc caagtatact tagtatcttt tggtaaatct
      181 tctttgttct taattccctc aaatgcgtct ggttccttat tcaattctgt agtcactttt
      241 tgaccttcag gattatattt gtcagcgtca gatttatcat ccagttttgt tgcacttgat
      301 acaaattctg tatcatctgc tgtaattggt tgagttgctt cctctggcca tttcgcatct
      361 gtataaccat cttttgcttt caacactgga agtttatctt ctggtaagct tacgccgtct
      421 ttcactgcaa agactgttgt tccactttca atacttgttc cttctcctgc ggtgaaggtt
      481 actttgtggt agcctgcagg aatgttttct cctggatttt caatgatatc atccagtttt
      541 gttgcacttg atacaaattc tgtatcatct gctgtaattg gttgagttgc ttcttctggc
      601 catttcgcat ctgtataacc atcttttgct ttcaacactg gaagtttatc ttctggcaag
      661 cttacgccgt ctttcactgc aaagactgtt gttccacttt caatacttgt tccttcccct
      721 gcggtgaagg ttactttgtg gtagcctgca ggaatgtttt ctcctggatt ttcataaata
      781 tctttactta cagttactgc taaatcggtc gtgcctacag aaccatcttg gtaaacaatt
      841 ttaataggaa ttgttccagt aatcggctcc gattctccta cacctttagc tggagtgaat
      901 gtaacaatac cagtgtttgc atcaacactt gcattaccga agtacttatt atagacatct
      961 gaaattgaaa aggcatcttt agctaaagga acatctggtt tatcaaatgt aggttttcca
     1021 ctttgaactg tcgtttctgg agttgttgtt ataggtacgt atgttgcatc attttccata
     1081 gcttgagaag cttttacagc aaactctaca tccacgtcga aagttcgatt tccgatctta
     1141 acagttacaa tacctttcgt actatcagta acgttagaag tatcaggctc tgttttccat
     1201 gaatactctg catcttcagg taagttttta ttattccgaa ttgattcttt agcatctggt
     1261 ttaaatccaa ctaccacggt ttgtttatca accgcttttg gtgattcctt aataacggtt
     1321 gaaccttctt ctggtttatc aaaacctgga gaaacgattt ggatttttaa ttcatctttc
     1381 gcgattaatt tacttgaatc tacacccgta aattcaaatt ctacagtatc tgaaattgga
     1441 gccccatctt tttcatttgg agcgatagtt ttttctgcta atacagtacc ttctttatca
     1501 acaagttggg ctttgtgacc tgttcccgct aactcgtgga tgaatacttt ccccttaact
     1561 gttgtgtcaa catcatatac ttcttctaat tcaggtttcc cgatatatgg attcgtgtct
     1621 ccgctctctt ctttatcgtc agggtttcca tcaccatcaa tatcttgcaa ataataataa
     1681 cctgttccat aagtgttctg gattaatttt ttattcgtat ccgacaacca agaatcaaag
     1741 atgaaatctt caccaaatgg tttattttct tcaacttgtg ctgttgcttt catatcttct
     1801 aagatttcat ctaatggctt agtcaattgt aaaacatatc gaataacgac tggacgtgga
     1861 cttgcattag caaaatcgat aagtttagtt aaatcattat tagttattga acctatgcca
     1921 taattttcat gaccttcccg tcgctcgatt gctaaatcag ctacttttgt tccggattca
     1981 aacgaaacat catatgttac tttgtcagcc tgaaccatgt gcatctgtat acccgctaca
     2041 tatggaacta atcgttcatc aattttgtaa ttagcatacc aaggcgtgcc ctttgcggaa
     2101 gatgaatatg agaaattata atttttcgtt aacttatgat ctaagattat agctccatta
     2161 gcacctgtgg atcctgaacc atcttttgtt tgagtattag gtttctcata ttttgcactt
     2221 actgatccat gtttaaactg gtcaggatta ttttcagata catctaagct attatagaaa
     2281 tcatctgaat ctgttaaaaa gtagcccgta ctatcaatac ccggtacaat tttatcatcg
     2341 tcttgatgac ttaccaagta gattcgatac attaaacgat cggtcttgag attgtctatg
     2401 cctatctctt taaaaatttc atctaggctc ttttcaaacg taattacccc attaggagcg
     2461 gtttgcgtat cggttgtttc tgccccagca aataatccat cacttgcacg aatataattg
     2521 accttccaaa tatttgtagg tctacccagc gaatcattaa ttcttacaaa ggtccgtcta
     2581 gaagatccaa ttcctttctt tggatcgacc tgaatttttt ctacatattt agctaatcgt
     2641 tcatctaatt gaagacggat ttcccagttt ttagttgatg ctgcaatatt atgttttccg
     2701 taaacttcaa atccaattgt attgcctttt agtgtgtctc cagttagttc ttgaggacta
     2761 aattgtaaat ccgaaaagtt ataatttttc gtataaccag gattctcctg aaaagtattc
     2821 cccgaagcta ctttgtcacc tacttgtacg gagcttatcg ctgtttcaag tgggctgctt
     2881 ggagaaattt catcttgtgc tttaactagt tcagttgttc ccaagacaag accaacacca
     2941 atcaaaacag atgcaacccc aacacttaat tttttgatac tgtacttcaa tactcgtttc
     3001 tttgtttttt ctagaaatac tctcttatta ttcttgctaa ccattattca aatcaactcc
     3061 cttaataatt actttcctag taagaataaa agataaatct gatacgtatt attcacagaa
     3121 taggaatctt actaacctta tgttaactaa tttacttaga gaatttcatg aacattacaa
     3181 caaaaaaagt acatttcttc atgttttttt cggatatttg tgctttttaa ccattcagca
     3241 gctgaaaaca tataaaaaga tatgtatgta ttctttctga aattaagttc atttctatgc
     3301 gatgaagcat gttttcaaaa tattaccctt tcttagatta aacttcagag tattcaaata
     3361 acggaataag gagccttatc ccgcattact gaatgagact gtgacataag taaaaaggtg
     3421 acttcaaatt ccttcttcgg aatttgaaat caccttcttt ataattataa agtatcggtt
     3481 tcacagcatt tctgaatgat tcctagaatc ttaaacgaat gattggagtt atcaacattt
     3541 tttcactcgt ttttagcgaa acaaaaaatg acatttgtca cagcctcatt aaattattga
     3601 ttctttttct ttataattga attgtccata tttaaagtgt ctagtactct acatgaataa
     3661 ttaattgctt tcactcaaat acttataatc tattaacttg tagttgttta acttttctga
     3721 aaaagttaga cccacgtaat aatcttccca gctttctctt tcaattaact gatccaattt
     3781 ttgataatcc ataaattcat catgtatcaa aaagaataaa taacttgata ttttagcatc
     3841 tagcttaatc agattaaata atgtttgttt aaaattgcta ccattaatat gactgataga
     3901 ttctctagct tcttcacata aactttttac tttattaatt actactttgt catattcatt
     3961 taacacacta ttattaccat tacttagacg ctcagattct acgaaacaac tcaaatcaga
     4021 aatttcccaa aaaaattttt tgttaaaatc caatttcctc aactcctcca aactacgtaa
     4081 atgatatagt ctcataataa aataaaacct ctcagctaat gttgttgaaa ttgtccacta
     4141 aacctaattg atattgctta ggagatacac ctgcgtactt tttgaatact ctcgaaaagt
     4201 gtgaagaatc tgaaaatcct aaacctaaag aaacttcact gatagtatgg tttgatttca
     4261 acattatttt agccgtagaa atttttcgct tagagatata attataaatc gtaatatgca
     4321 tttcattctt aaagctttct cttaatttag tttcacttac agaaaaataa ttagctattt
     4381 cctttacagt aattctttta tagatattta agccgatgaa ttgaacgaca gaagaaatta
     4441 agggagaaag atgctctatc ttagtttttc cgatttcctt agtataataa acaatcccag
     4501 aatccctcac ttttaagacc tcaggtaacg atacagctaa ttcgttttct tgtatcaaag
     4561 catctctact ttgatacgct tctattatat ccattcctaa tgttatagac gtttgtgcta
     4621 acttttcaaa aacaatgata gaataatttt tttcagaccg aatcgtatct ccactaacac
     4681 ttggaattat tccattactc agattaaaaa ccatgttttc taaatttcga atatctccat
     4741 ttttaacata ttccagtatt ttattttcat aaagaaacag atatatttct ggatcgtaat
     4801 tttgtgataa cagattatct attttgattt gctcgatagt tttacttaga ttttctgtat
     4861 attcaattaa cggttcatgg aatagatctt ctatttttcc agtaaaaaaa taatgaacta
     4921 aaatcagaat atctcgaatg tctcctaaag aatacaaagt caaattttgc aatgaattat
     4981 agagtcgttc tctatcagcc attgcaacat tcaaattgtt catttttagt ttaaaaaaaa
     5041 ctttatcaat attatttgct ctaaatggac caaataagta atatctggtt ttaaacatgt
     5101 atagaagaaa catctcatta aaatcaccag taaagaaatg gaaatcttta gtttttttaa
     5161 tattatcagt tagtaacttt ttataatcat aaaaaaaata agtagttcta tctgagcgat
     5221 actcttttat aatactgaat tcggaattaa aaaccacgat aggtaacttt aaacaaacat
     5281 gaagagactt taataagact tctttatctg aaaacacttt tgtttctctc tttcctttct
     5341 acatcattaa atagtatttt atacgttatc taaaatacta ttcctctgtc aaaataagct
     5401 aacttacttc attataaaat atccacttat cgctttcatg tatattccac cgtaaaaagt
     5461 acattttatc accgagaact catcattttt catcatgatg aatactattt acatatatct
     5521 agttcaaaga caataattat tatgatccgt tattatctaa gcactataca gataatagga
     5581 atttttcgtt tctaaatatt ccaatttggg aatccaataa aaattttcgt tcaaatacgt
     5641 gtctattcga actcttttct agttgttaat tatgaagggg gaagaaataa aaaatacaat
     5701 ctatacacga ataagaatat tatccaaaag gaggttttag aaaagattta ttatacgtaa
     5761 aaagctcaag acattttctt agccataagg acatgtttga tatttaagaa gatatatgaa
     5821 ttttcttttc taagtataaa gataactatc cattatcaac taaaaaaaca tttttgaaaa
     5881 taaacatcag cagtcctatc aatgcatgtg agcttataga agttattcgc agcgcagcat
     5941 aattgcatta gcttcttttc gtgttttttg cctcttttcc ctttaaatct taatggagga
     6001 ggtgtgcaat atgtcagata acgacgaacg cgtaaatgcc cagttgattc gattctttga
     6061 aaaggtcatt ttgaacaccg ctaatactta ttataaaaaa caagaagaaa ttcaaaaaca
     6121 tgaacaactt gatcaactcc caccatattt gtttactaaa gatactataa aatttaaaca
     6181 accgattaat gttttaaatg tgactctcct tgttgaagat ataaaattag caaaaatcct
     6241 tcctttgttg aaagaacctg aacaaatttt tcttatcgaa aaatttatct ttgataaaac
     6301 tgataaagaa attggaaagg ttctggggat tacaagacag ggtgcgacaa atttaaaaca
     6361 tcgactttac aaaaaaattc aaaaaatgct ggtttaatat ctgcataata actaattttg
     6421 tatgcttctt tgctcgttct cctccttccc aaagaaatag attataagtc catgggaaga
     6481 aggtagattt atgaattctt taaaagaaga tttcatttta gcaaaggctg gaaatgaaga
     6541 agctgttgag gcaattctca aaagatttag ctctttgatt cataagcaat cctggagaac
     6601 tggaaaatat gatcaagatt gttatcaaga atgtatgctt gcaatatatc tagctatctc
     6661 gaaattcgaa attaaagaat aactcaacta agggagtctg tgacataagt aaaaagatag
     6721 tttcaaattt cgaacaataa atttgaaact atcttcttta taattataaa gtatcgattt
     6781 tacagcgttc tataatgatt catagaatct aaaacgaatg attttaatta tcaacgtttt
     6841 ttaattcgtt tttagcttaa aaataacttt tgtcacagtc tcactcctaa aattacttta
     6901 tttacgtatg aagtgggcag gaggtcgaat ccagaactgg gctatggtac ttcaacgagg
     6961 acttctcctc tagaattgaa aagcatgcga tttaccttcc gtaacgacgg tagatttatt
     7021 caactatgtg tccaatcaaa atttgtctga tttcaaaaat agtcaagaga attttggttg
     7081 ttaaaaactc ttatctatca acttccacag tttagttgac aaaccctgat actaagttgg
     7141 gctatgatac acttttcttg actatcagtt acgttaccgg aaggaatgaa ctctattgag
     7201 aaaaacatat gatcgtaaat ttaaactaaa gatttcacag gatatccttg agaaaaaagt
     7261 aactaccaag aaaattgctg aagaatacaa tatctctcgt ccaacaattt cccgatgggt
     7321 ttcagaatat cgtcgatacg ggaaaaatgc ttttgctgga caaggaaaaa gattacctga
     7381 taaagcagat ttctacattc ttgaacagga aaataaacga ctaaaagagg aagacgagtg
     7441 ttctacgaac acaaagatcg atacggatct ccagggatca ctcaaaaact ttacgatgaa
     7501 ggaatcgaaa tcaataaacg tgttgtagct gttcttatgc gtgaaatgaa tttatgcaca
     7561 agaggatttc atcgacgcaa atcttctcat ggtagagaaa aaacaatcaa agaaatggta
     7621 aaaaaatgtt gaatcgataa tttgaacaga accaaattga tgctgtttgg gtgatggata
     7681 ttacttacat tccatgtaat gacggtcgcc tctatttgtc cacctatatt gacttagcaa
     7741 ctcgtattct acgttactat atggtagatt cacacatgaa aaaagagatt gtcgtccgtc
     7801 cattacaaat ttattaagga gaattgccta cggtaattca ttccgataga ggtagccagc
     7861 atcggtcttt tatttatcaa gagctgttga acgaccacca catcacacat tcagtgagcc
     7921 aaactgggac tcctgttgac aatgcagtaa ttgaagcgtt tcatcgatca atcaaatgag
     7981 aattaatcga ctccaacaaa tataaaagta aaatagagat gaaggtgtta atccaagatt
     8041 atttagaaga ctactaccca aacaaaagaa tccatacaaa atttatgatg actccttgac
     8101 aatttgaagc gaagaaaata agggatctat aatatctagt gttggtgacg ccttctgttg
     8161 ccaatacttt ttcttttttc taataaacgc aaacagacac cttaaaatcc tttagaataa
     8221 agtcgacgaa aaccattcaa aggagtgttt caagatgtcc tattcagagt ttaccaaaga
     8281 gttactagat attctagacc taaatcttat ctttcatgaa gatgcctttc gcaaagagcg
     8341 aatcaatgac gaaacatgtt ttgtttttga tggcacattg acctatcaac cggaggaatg
     8401 ctttcatcgc cactatcaaa atgaacaaac gatcattaaa tagggctgga aaaaagtatc
     8461 catcttattg aatgatgtca gtaactacaa gaccattctg cggattaaca aacagcgctt
     8521 caaatgtaaa cactgtggaa agactttttt agcagaagat tcagttagtg atcgtcgctg
     8581 ctccattgct cgcagagtca aacaagccat tcttgagcta ttaagcgaac ctctttctat
     8641 gtctttgatc gcacgtatga agcacatttc tccgaccact gtcattcgaa tacttcgcag
     8701 ccttcggcct aaaaccattt ctttgagcca gctgttacca gaagtggtgt gtttcgatga
     8761 attcaaatca gtgaaaaatg tctcgggagc catgagcttt gtcatgatgg acggcaagac
     8821 ccatcaactg attgatattg tggaaaatcg gcaactcaat cctttacgcg actatttctt
     8881 gcgctaccct ataaaagtcc gtgaacaagt gcgtctagtg gtttcagatt tctatacacc
     8941 ctatcgcaca ttggtgaaag agtgttttcc gaatgcccga atcgtcgccg atcgctttca
     9001 tattagccaa cacattggtc gggcttttac caaccaccga attcaagtaa tgaagacctt
     9061 taaaaaaggg gatcgtcggt cgaagcactt aaagaaatac tggaaactac ttcaaaagaa
     9121 tgcgtgggaa ttgaaaggtc agcatcgcta ctggcgtccg tcatttcgag atcatctgac
     9181 agaagcagag atagtcgatc ggctattatc ttatgatgat tccttaaagc gaggctacga
     9241 agtctaccag gattttcttt ccgttatcag aagacaagat gttcctgaat tcgtcgcgct
     9301 cctaaaagaa gactacaagg agttgccaga gcactaccaa ccagtgttca cgaccttcaa
     9361 gaaataccaa acagaaatca aacgagcgtt gcgcgttccc tattccaacg gccctataga
     9421 atgtttgaat aaccatatca aagtactaaa acgaattgcc tatggctata gaaactttca
     9481 aaactaccga gaacgaatct ttttatatcg aggaaaatat tttaagaaaa ctaagaatac
     9541 tacccaactg actaaagcca gaacaacaac acggctagac aagatagctg tctagccgtg
     9601 tgagtatctc gattattcta ttgaatttct tcaccaacac tcattgacga agagccaaaa
     9661 taagtaatct aaccgactgt taactaaacc attgcaggtc ccgttaaaga tacttgtgcc
     9721 tgttgtcacc gcttcttttt cttgtccaca agcgcttaac acacttaata aagcccctgc
     9781 tattattaat aataatatct ttttcttatt aaaaacctcc tcatctattt ccagattagt
     9841 aaatgtagta atctgtgctt tcttttttct caatactaat aactaactta tggggtaaac
     9901 aaatactcgt ttgaccgggt tttgagatcc atccagttct aaccgcgatt tgatcaggac
     9961 tattatcttc tttaactcga attcttccat ctttaatctc aacaatatta tattgtccct
    10021 tcgcaggatg ataattcacg agtttatgat tgatcttatc caaatcgaag cgatccattt
    10081 ccttgccatc aattcgaacg atggcatatt tgatagcatc ttcagttgtt tcattctcct
    10141 tttctataga gaatacaaat aagggaataa aagaggtaat aatcaaaatg ccaataatta
    10201 tgacatcgcc tatcttgaca ccagcttttc ttaaaaattt cattaacgat atctggctaa
    10261 acatattaga ctttttccat ggaaatggtg aaatttttcg gaaattatct gcattaagag
    10321 aatcagttaa acaaccctca agttgttcct taatacattg ttgatccatc ttcataccaa
    10381 taaaaactag tttattaatg cgttcaccaa acaacggatg ccaggcttcc ttcaattcgg
    10441 gatttttttg tataatcatt tgacactcaa ttttaggtaa actagctacc caataattta
    10501 atgattcaat acttttatag ctacccgatg tttcaaagat cgtcgaaaaa tcactatgtt
    10561 gggcaaacca aagaaaccct tttgctcttg taatattgcc aggaaaattt ttatccgtaa
    10621 gatgggcaaa tttttgtgcg tcaaggagta accgatttcg atagataaaa cttgagatac
    10681 catattcttc tgtttcagga atatgatttt gatagccaag ctctaactct ttgaaccagc
    10741 ccactgaata ggaagtctca tctatattaa aaagatttgt atttagaatt ttcgataagt
    10801 ctacttcacc tttaattgtc ctaattattt tggcattgga ctgtaactta gcaattagac
    10861 cgttaatttt gtaaatcgtc ttggttgaca ctaagtcact attatttaaa agtaatatgt
    10921 tacaacactc gaattgatca attaacaagc cacgaatatc ctgttcttct tcaactacat
    10981 taccttcagc ttttctttcc tgaatctttt cacccgtttc gaaattatcc caaaaacgtt
    11041 ttacatccac tactataata atggcaccaa tctctaatcg ttgggtcaaa tcaatgtcta
    11101 aagggttttt agctaatata attgcttgaa taattggaat tggtttgctg attcctgaag
    11161 cttcaataac aatttgattc aagtcagaaa attgcactaa ttgatctagt tcaacaatca
    11221 aatcttcgcg taatgtacaa caaatgcatc cattcggcat cgaaacaagt ttttctccag
    11281 ttcttttaaa acctttcttg tcgactaata ccccatcaac atttacttcc cctatgtcat
    11341 ttacaatgac agcaatttcc tttccgtgat caccgtacag aatatgattt agaagtatcg
    11401 tttttcctga accaagatag ccagttaaga ttgtaatagg tatttttttc atagggaacc
    11461 tctttctata ccttgaattt acactttaag tgcaacacat aaaaatgagt cataatcgat
    11521 atccaactag tataagtttg tcgagaacac tcctagaagg aaaataatta tgagccagta
    11581 tcgtcatctt actatactcg aacgagaaag aatctttctg cttcacgaag aaggattttc
    11641 tattagtata attggcaacg acattcagca tagcccgttt actattttac atgaactgag
    11701 aagaaacaag aaaaaaacta ttcaccttcc aaagcggaaa aaaattatgc ttatcgaaga
    11761 aaaaaatgcg gacgttatca cattctaaat gatccgtgag tttggtcaat tgttcgtcat
    11821 ttatttgtcg attttcagtg gtcgccagag gaaatctcga atcgtttgaa gcatgaacat
    11881 atggactttt caattagttt tatcacgatc taacgtgcaa tttgcaatga tcttttcgat
    11941 acagaacccc tctcacacgg caataaaggc ctgatccgtt cattgcacca tcgaggaaaa
    12001 acaagacata caaaaaatca tgtcgagtct cgtggaaaga tttgccttac tcattcgatc
    12061 catggccgtc caaaatccgc agatgataga agtgattttg gtcattggaa agccgatatt
    12121 gtagctggca aaactggtgg tacttgttta gtgactttga cagacagaaa atcatgcttc
    12181 cttttagcag gaaagaaggt ccccagaaag aaagccgctt atgtgagcga gaaaatgatt
    12241 gaacttttaa gcagtattcc aaatgaggcg gtcaaaacga tcactccaga tagaggaaaa
    12301 gaattctcca atcatttcgc agttacagaa gcattgaata atatgccctt ttattttcca
    12361 gatcctcatg cccttggcaa caatgaacaa attaaaatac gaatagactc attcgagaat
    12421 acttgccaaa atcgaaagag atagctacgg tagataactc aacgataaat cagatgattg
    12481 aaaaactgaa taacagacct agaaagtgtt tagattggag aacaccttat gaagtcttct
    12541 ttgataaagt gttgcgcttg atttgacaat tcaagacata ataaaaagca gatcaaatcc
    12601 aaataaggga aaaatgatct actctggtat tatcaattaa ttggccaagc tattatgccg
    12661 ttttgctaaa cgtctacttc ttccagtatt gaccttgata aaacaacaat caggatcccg
    12721 ttttaatact ctatgaactg tgtcaatact aacatgtaaa gttgcagcaa tatcagctaa
    12781 tgtactccca tttaatctca tttgctttgc aaatcgataa cgccgataag catcaatatt
    12841 cttggaatcc atagacaata atacttttct taccatgtat ttcctccaaa aattgaattt
    12901 taatgagcca tcatttcttg agcaatttca tgtttagaca atgaagctgg atagaaagta
    12961 ggccaattat gcaattcatt atagagtttt tcttgacttt ctccaccaaa gaaaatatgg
    13021 aaatgctctg ccttacttgg tgcaattcca tgatcactaa attgaatata tttaaaacga
    13081 ccagcacctg catcatcagt ttcaaaatta aaacgaacac cacggtttcc tttttcataa
    13141 ttcaaaattt tgtatccaac atatttgtat gtgtattgat gatgttcacc gttgactaca
    13201 aaatcaatgg tgttgtcttt aatgttgata gtatcaatat ctgtcttata gccagtagta
    13261 taataatctt tgtactcgg
//
LOCUS       DAXLPY010000064        13060 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.064, whole genome shotgun sequence.
ACCESSION   DAXLPY010000064 DAXLPY010000000
VERSION     DAXLPY010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.064"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..1007
                     /locus_tag="ACF3UF_002108"
     CDS             <1..1007
                     /locus_tag="ACF3UF_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3672195.1"
                     /translation="LKDAKVVSGEQRINREDLSDEFKNVVSLEATNNTKRNILFSSGV
                     FTIKEGKNIEENDKNSIIVHEEFAKQNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGI
                     FSGKKQETYTGLSSDFSENMVFVDYSTSQEILNNSENNEIANKILMYSGSAESTDLAL
                     NKLKELKIDESKYFVEKDSNAFEESLESVSGIKYIIKVMTYSIMLGGMVVLSLILILW
                     LRERIYEIGIFLSIGTSKIQIIMQFIFELIFISIPSIISSLFLGNVLLKVIVDGFINS
                     EDSMISGGSLINNSSFMSNITTLGQSYLILISIIVLSVVFASSLMLIKKPKEILSKIS
                     "
     gene            1017..1673
                     /locus_tag="ACF3UF_002109"
     CDS             1017..1673
                     /locus_tag="ACF3UF_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3672196.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            1673..3049
                     /locus_tag="ACF3UF_002110"
     CDS             1673..3049
                     /locus_tag="ACF3UF_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3672197.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3263..3592
                     /locus_tag="ACF3UF_002111"
     CDS             3263..3592
                     /locus_tag="ACF3UF_002111"
                     /inference="COORDINATES: protein motif:HMM:NF013068.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3672198.1"
                     /translation="MQDVLKDVFGPLFEKMLQGELNNHLGYDAHSKEPKKHDNRRNGY
                     GNKTLKTSFGKVNIDVPRDREASFEPELIPNRKRDVSDIADCRQKLFQTRNSSLEQLF
                     IYFVSNF"
     gene            complement(3515..4975)
                     /locus_tag="ACF3UF_002112"
                     /pseudo
     CDS             complement(3515..4975)
                     /locus_tag="ACF3UF_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            5609..6580
                     /locus_tag="ACF3UF_002113"
     CDS             5609..6580
                     /locus_tag="ACF3UF_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFD3672199.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            complement(6557..6646)
                     /locus_tag="ACF3UF_002114"
                     /pseudo
     CDS             complement(6557..6646)
                     /locus_tag="ACF3UF_002114"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(6658..6894)
                     /locus_tag="ACF3UF_002115"
     CDS             complement(6658..6894)
                     /locus_tag="ACF3UF_002115"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3672200.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(6863..6994)
                     /locus_tag="ACF3UF_002116"
     CDS             complement(6863..6994)
                     /locus_tag="ACF3UF_002116"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3672201.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            complement(7070..7453)
                     /locus_tag="ACF3UF_002117"
     CDS             complement(7070..7453)
                     /locus_tag="ACF3UF_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFD3672202.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            complement(7486..8271)
                     /locus_tag="ACF3UF_002118"
     CDS             complement(7486..8271)
                     /locus_tag="ACF3UF_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFD3672203.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            8449..9549
                     /locus_tag="ACF3UF_002119"
     CDS             8449..9549
                     /locus_tag="ACF3UF_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3672204.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            9539..10363
                     /locus_tag="ACF3UF_002120"
     CDS             9539..10363
                     /locus_tag="ACF3UF_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFD3672205.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            10360..11175
                     /locus_tag="ACF3UF_002121"
     CDS             10360..11175
                     /locus_tag="ACF3UF_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3672206.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            11172..12002
                     /locus_tag="ACF3UF_002122"
     CDS             11172..12002
                     /locus_tag="ACF3UF_002122"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3672207.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            12009..13040
                     /locus_tag="ACF3UF_002123"
     CDS             12009..13040
                     /locus_tag="ACF3UF_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3672208.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
BASE COUNT         4078 a         2271 c         2779 g         3932 t
ORIGIN      
        1 aactaaaaga tgctaaagta gttagcggag aacaaagaat aaatagagaa gatttatctg
       61 acgaatttaa gaatgttgtt tcactcgaag ctacaaataa tactaaaaga aatattttat
      121 ttagtagtgg agtatttaca attaaagaag gtaaaaatat agaagaaaat gataagaatt
      181 caattattgt tcatgaagaa tttgctaaac aaaacaatct aaaattaggt gatgaagttg
      241 atcttgaatt actagatatt gaaaaaagtg gaaaaataaa aagtcataaa tttaaaatta
      301 tagggatctt ttctggtaaa aaacaggaaa catatacagg attatcttct gattttagtg
      361 aaaatatggt gtttgtagat tattcaacaa gccaagagat attaaataat tcagaaaata
      421 atgaaattgc aaataaaatt ttaatgtatt ctggtagtgc agaatctaca gacttagcct
      481 taaacaaatt gaaagagctt aaaattgatg agtcaaagta ttttgttgaa aaagattcta
      541 atgcgtttga agagtcttta gagtcagtga gtggaataaa atatataata aaagtaatga
      601 cttattctat tatgttaggt gggatggttg ttctttcatt aatcttgatt ctatggttaa
      661 gggaaagaat ttatgaaata ggtatattct tatctattgg aacatctaag atacaaatta
      721 taatgcaatt tatattcgag ttaatattca tatcgatacc aagtataata tcttccttat
      781 ttttaggaaa tgtattacta aaagtaattg tagatggatt cattaactca gaggattcaa
      841 tgatttccgg tggaagttta ataaataata gtagttttat gtcaaatata acaacacttg
      901 gacaaagtta tttaatatta ataagtatta ttgttttatc agttgtattt gcttcttcat
      961 taatgttaat caagaagcct aaagaaatct tatcaaaaat aagttaggag aaaataatgg
     1021 atatattaga aataaagaat gtagcatata gttatgcaaa ttctaaagaa aaagttttgt
     1081 caggagtaaa tcaaaaattt gaacttggga agttttatgc gatagtagga aagtcaggaa
     1141 caggaaaatc tacacttctt tccttacttg ctggacttga taaacctcaa acaggaaaaa
     1201 tattgtttaa gaatgaagat atacaaaata aaggatatag taatcataga aaaaataata
     1261 tatctttagt atttcaaaac tataatttaa tagattattt atcaccaatt gaaaatatta
     1321 gattagtaaa taaatcagca gatgaaagta tcttgtttga actaggttta gataaaaaac
     1381 aaataaaaag aaatgttatg aaattatctg gtggacagca acaaagagta gctattgcta
     1441 gagcattggt atcagatgct ccaataatac tagctgatga gcctactggt aatctagaca
     1501 gtgttactgc tggagaaata attaatatat taaagacatt agctaaagat agaaataaat
     1561 gtgtaatagt tgtaacacat agtaaggaag tagcagattc tgcggatatc attttagaac
     1621 taagtggtaa aaagttgaaa aaagtaaata aaatgaattt ggaggttgaa taatgataaa
     1681 aaatgcattt gcttatgtaa ctagaaaaag tttaaaatca ttaattatca tattagttat
     1741 tttatctatg tcaactttaa gtctcattag tttatctatt aaagatgcta cggacagagc
     1801 ttcaaaagaa acatttgcta atataacaaa tagtttttct atggagataa atagacaagt
     1861 aaatccagga acacctagag gtgggggaaa tgtaaaaggt gaagatatta aaaagatatc
     1921 tcaaacagat agtatagact cctatgtaaa aagaataaac agtgttgcag atttagttga
     1981 ttatgatatt attgaaactc aagagactct tgcgaatcaa tcacctgaaa gagcaaagaa
     2041 ttttaaaaga acagttatgt taactggggt taacgactca acaaaagaaa caaaatttgt
     2101 atcagaagca tataaattag tagaaggaaa gcatttagaa aatgaagata aaaataaaat
     2161 cttaatgcat aaagatttag ctgaaaaaaa taaccttaaa gttggagata agataaaaat
     2221 aaaatctaat ttatttgatg ctgataatga gaaaggtgca gatgaaacag tagaagtaga
     2281 aattaaaggt ctattcgatg ggcataatag cggtgtagta agtgcagcac aagaactata
     2341 cgaaaataca ttaatcactg atattcatac agctgctaaa gtttatggta ataccgaaga
     2401 tacagctgta taccaagatg caacattctt tgtaaaaggt gataagaatc ttgatagtgt
     2461 aataaaagat cttgggaaat tagatataaa ttggagagaa tataatttga ttaaaagttc
     2521 atcaaattac cctgcattac aacaatctat atcaggtatt tactcaattt caaataaatt
     2581 attttttggc tcattaatat ttgcaggagt tgtagtttca ttattattat tcttatggat
     2641 gaatgctaga aagaaagaaa tagcagtatt actatcatta ggtatatcaa aattagaaat
     2701 ttttggtcaa ttcctaattg agatggtatt tatatcaatc cccgcattcg ttggttccta
     2761 tttcttagct caatatacag ctgacaagct tgggaataat atattgaata aggttactgg
     2821 tgatatagct aaacaaatag ctaaacaatc tgcatctagc caattaggtg gtggggcaga
     2881 agctgaagga tttaacaaga cattatcaag tttagatatc aatgtattac ctaaattcat
     2941 gatttatgta gttatattta tgagtttagt acttcttgta tcattgatta tttcttcatt
     3001 caatatatta agaaggaatc caaaagaatt attaattgac aataattaaa attttcggtg
     3061 ctttttagca ccaaaaatga gagtgtaata taaaccgtgt aagtaaccat caatcctagg
     3121 cgggtggttg cttcacggtt tttatttttc taaaataaga tcaagaggtg attacacgat
     3181 ggctagaaag aaaagaaatc ctgatgctga gaagttagct gaatccattt tgaatactta
     3241 tcaacccgaa tctgtagagg atatgcaaga tgttttaaaa gatgtgtttg gtcccttatt
     3301 tgaaaaaatg cttcaaggag aattgaataa ccatttaggg tatgacgccc attctaaaga
     3361 gccaaagaaa catgacaatc gacgaaacgg ttatggcaat aagacgctta aaacgagctt
     3421 tggtaaagta aacattgatg ttcccagaga ccgggaggct tcttttgaac ctgagttgat
     3481 tcctaataga aaacgagatg tctccgacat cgcagactgt agacaaaagc tgttccaaac
     3541 tcgtaactcg agcttggaac agctttttat ctacttcgtt tcgaattttt gaacaaaaaa
     3601 ataaaggctc cttgcctttc catagccagg tggctaattt ctttaaattc attgcagcaa
     3661 acactagcat cgtatgcgtc gcgacttttt ccaagcctcg atacttggtc caacgcatcc
     3721 catgcttttc ttttgcatcc gcaaatattc gttcaatcgt ttgtttccgt tttttgtaaa
     3781 ttgatttatt cagatctgtt aggcgaagat gttccacttc atccatcaga tctccccaaa
     3841 catgtctcgt gatgactcgt tgatgatttt tacttatggt acattggttt agcagaggac
     3901 agttcacaca ttcttttgga ttggatttgt attctcggta cccttctcga gtaaccgttg
     3961 aaaaagcgag catttgatct tgcggacaaa tataacaatc aaaatactcg tcatagagaa
     4021 actcattttt tgataatagc tcctttttcc ctttgggcct tgaataaggc aaacaaggtc
     4081 gaaggttcaa atgagtcaaa aagtgaacaa acttaggtgt cttataccca gcatcagcga
     4141 caacacaatt gatttcagga aaaagtctct tcgattgttt gacgagctga aaggcgactt
     4201 gactgtcatg aatatttcta ggagtgatga ttgtgctaag aataaatcca ttgtcgtcgc
     4261 atgaagtatg gacagaataa gcaaattgtt tttctcgttc gcctttgacg tagtagccgc
     4321 tttccggatc agctttactt atttttcttt ctttcagctt cacttccttt tctaagtcca
     4381 aagtaaaagg gcgttttcca gcctctattc gttgacgatt gatctcatct tctaattcat
     4441 cctgataggc tttcgcttca tcatgggtca tttctttcgt aaacttatgt ttattggcgt
     4501 tagctttgat gtgggtagaa tccagataca aattatcctc tgttacaaaa cctgctttaa
     4561 ctgcttgttc taaaatatag gcaaaaatat cctcaaacac cgtcgtttct ctaaatcggc
     4621 gaacataatt ctttccaaaa gttgagaaag gggggatttt ctcctcgaag gagtagccta
     4681 aaaaccagcg gtaagcgaca ttggtatcga cttccttaat ggtttgtcgc atggaacgga
     4741 taccgaataa atactgaata aacaccaatt tgatcagaat cactggatcg atacttgggc
     4801 gacctaaatc ggagtaagtg gcttcgacga ttggataaat aaattcaaaa tcaagcgcgg
     4861 catcaatctt tcgaacgaga tgatcttgag gaactagatc atcaatcgta agcatcgcaa
     4921 attgatttct accattcgta ttgtttttag acatcatagc tatcactcct tgcattcgtt
     4981 ttcataaatc tattataaaa gaaaagactg tagacatcat ccataaaatg gactttgtct
     5041 acagtctgga taacgtgatt ttttgctgta atgacaaggt tttagctgtt tcagatacca
     5101 tgtatccaaa aatagtttat tgagaaaata ggagagtatt tgatactaac tagtaggaaa
     5161 aaatgagata aaaagtaaat ggaatcattt aaggtaatct gaaataaaaa atatacagcc
     5221 ctgtggtact ttacctacaa ggctgtatat attttttact ctcagcgttt ttgactccgt
     5281 gtctgactcc gttttattga ttttgaatgt tattcaatga ccatttaaca ggtcaaattt
     5341 gatgtttttg attccgtatg acgccgtttg atatctagtg atatagtgat ttgagtctac
     5401 atcgaataag ggaataaacc aataaaaaat gatttagaat attaaaataa caaaaaagag
     5461 gactacctgt attagtcctc ttttttgacc agattttgac cagtctattt tacatcctag
     5521 tatatttata tgagctaatt ttatgattaa atggtaagtt tttccttgtg tgttttagtt
     5581 taaactagtg tgtaattcaa aaatctatat ggaaggaaca gtattaagaa tagaacaggg
     5641 ttctctacat gatggtgctg gtttacggac cgttgtttat ttaaagggct gcccattacg
     5701 ctgtgcctgg tgttcgattc ccgaatcaca aagcaagcag attgaaaaag gatttggcca
     5761 gaccatgacc gctgaagagg taatggatga gattgagaag gatgctgttt tttactttca
     5821 ctcggatggc ggagtgacca ttagcggagg cgaggcactg gttcaggcgg attttgctaa
     5881 agaaattttg caaaaatcga aatacattgg aatcaatacc gtactggaaa ccagcttttg
     5941 tggtgcttat aatgaaatcc aaaaggtagc tccctatgtg gatacattgt ttgtggatgt
     6001 aaaaatgttt accagcaagc tccacaaaca atggaccggc ttagataacc aacaaatttt
     6061 gaagaatatt cgtcgctttt taattgagta tcctaactgc gaagtgcgaa ttcgagttcc
     6121 tgtggttcca ggtatcaata tgaacctgac cgagctgctg acgattgctt gttttgtggc
     6181 agatcttgat cggttcgtac cgttagaatt actaccgtac cactgctatg gtatgcacgg
     6241 ttaccaagca ttgggactgg agtatccgtt ggcagacacg ccagcgcctt cacctaaaga
     6301 aatgtttgca ttggcagatc aactggctcg cacggttcct catttgctgg tcacagcttt
     6361 aaccaaaaca tttatttatt tattgaatcc aagctttatc ttatggataa atgaaagaca
     6421 ctcactagct gcagccagct caagaataga gcttttgctg aagtcagtga gtgtcttttt
     6481 acgatgtttt ttcgaagtta atttgtcgaa tgaacactgg ctcaatcggt acatcttcac
     6541 tgtttgtcgg ctgagctgcg atcgctgcta cgatttctaa cccttggtat acctgtccaa
     6601 aaacagtata acgaccatcc agctccggta gtcctccaag ctccaagtat gcttgcttta
     6661 cattagcagg tcagcctgcg cctttgtgtt ttgcacaata aaaaactggt tgccgttggt
     6721 gtgggggccg tggtccccta aggccaaggc gccattaaaa tgataaagtc cgcgatgcac
     6781 ttcatcagcg aaaaagccct catagctgga aacagcttca tcaccagaac catccaaagc
     6841 gccaccttga ataacaaatt ccttaatgac acgagccgaa aggtgtgttg tcataaacgc
     6901 cttgctcagc tagggagcgc cagttggcta cagccagggg agcttggtca ggaaataagc
     6961 ggagacgaat ttcaccagca tcggtgacca gcacacaaac ttcttcctgc tgcggttttt
     7021 ctaattgaaa gagaggaagg tttgcaactg aaacgccttg atcctgccat caaatatcga
     7081 aaatccgcca ctcgaccttc gcctgatcac caaggcgagc cattcccaat aaaacggtat
     7141 aggcggtttc atccgcttga aaggtcaatt gcagctgtcc tcgtaaatcg ttgtagtcat
     7201 ctggggcggc tacttgataa aaaagatgaa actgcgcatg caaatattcc aaaggctgat
     7261 ctttaaaggc tgcaaaataa gcctgaactt tttcccgctg caagctgtca gccaccaaaa
     7321 aattttccag ttgttgtttt ggaacggctg ctaacaagga tcggcaaacc gcctcaattt
     7381 tcaacgcatc ccaatgtcgc gcaattaaat aatggatggg tgcctcttga ttgtagtccc
     7441 acaggttgct catttttttc accactttct tctattatat aggaatcaca aaatcggcag
     7501 cggcgtcagg cggcgttctt ttccttgaat gactagcaac ttttctacct gacagtctgc
     7561 caacagctga ctcatttttt taaagcccag ctgataatct tcggcaacat gagcatccga
     7621 gcctaaggta aagagctttc cgccgacact ttgatacaaa ggaacggcat aacggtaaag
     7681 gtcttcgttg ccgtatttca agaagctctt ggcatttaac tccatcgcca attctcgttc
     7741 aacaaccttt ttgaaaatcg ttagcagctg agcctcaaaa tgctccgcga attcttccgc
     7801 tgtgaaggtg aagcggcgta atccataatc aaagtgagtc aaaatatctc cttctggaaa
     7861 atccgtcaag acctgcaaca tctgatcaaa atattccttg gtagtttgaa tgggatcttt
     7921 ggttaaaacc acatcgtcca tataatcaaa gcggccattt tgatgaatac ttaccagctt
     7981 taaatcataa ggatgctgag cgaggtaatc cacgatccgc tcttcttgtc ctggaacaac
     8041 gccaatctcg atacctcgca gaaatttggt ggaataggtt tcttttaaag agtccagttt
     8101 gtttatatag gctggataat ccggaatgtc atcttttccg gtagatggat tgtttaaatc
     8161 aaagtgatcc gtagaaacga aaaactccgg ctgataggct aaatagtttt caaatttttc
     8221 ctctgaatca aaggaaaaat acgtgtggag atgctgatca taatactgca tagggagcct
     8281 ccttttttct actatcatac cgcaaaagct ttagaaggtt aacgggaatt cgtcgaaatt
     8341 tacaaaccat atacaacctt tacattgttc atgaaacctt ttcaagaaac tgattctctc
     8401 attacaaagc tttgttagaa tggaattatc gaaaggggag aagaatgaat gaaaatgaat
     8461 gaaaaaattc gtaacatgac tatcggttta ttttgtgcag caacagtaag tatcctgctg
     8521 acaggctgcg gctcaggtga agcaacgaag caatcggctg cggcagacga ctctttagat
     8581 acgattatag aaaaagccaa ggaagaagga gagattgcca gcttgggaat gccggatact
     8641 tgggcaaatt gggtaggcac ttggaacgac cttgaaaaag aatacggctt aagtcacgtg
     8701 gatacggata tgtccagtgc agaagaattg gctaagtttg aatcagaagg aaaaaatgga
     8761 accgccgata ttggtgatgt cggtatcagc ttcggtccgt tggctgaaag caaagagtta
     8821 accttacctt ataagaccaa ctattgggag gaaattccgg attgggcaaa ggatgatgat
     8881 ggggattggt tgttaagcta tacgggaacc atttccttta tcaccgataa agagaatgtg
     8941 aagcaagcac cgactagctg gaaggagctg caagagggtg actatcaagt tagcgtgggg
     9001 gatgtgacga ttgccaacca agcacaattt gctgtattgg ctgcggcgat tgccaacgga
     9061 ggtgacgaaa aggatattca gccaggtctg aattactaca aaaaaatggc agaaaaaggc
     9121 cgtttgtcca ccgttgatgc cagcgtagca aatcttgaaa aaggtgaaat cgatgtggca
     9181 gttgtttggg acttcaatgg actaaattat cgtgaccaaa ttgactccga gcgttttgag
     9241 gtaactgtgc caacagacgg ctccatcatt agcgggtata caaccttaat caataaaaat
     9301 gcccctcatc ccaatgcggc aaagctagca cgggaatata ttttatctga tgaagggcaa
     9361 atcaatttgg caaagggcta tgcgcgacct attcgcaagg tagagctgcc taaagaagta
     9421 gctgaaaaat tactgccgga ggatgcttat gaagcggcgg tgccagttga agacaatgaa
     9481 gcttggaaca agacctctgt agagcttcca gagctttggc aggcggaggt actgacctat
     9541 gcaaagtaga cttgacaaac tgattgtagt tatactagac ggctgtcgct acgacacagc
     9601 cgtcgcccag cttgggttca tgaatcattt agttgagcac cagcaagcaa gcttattgaa
     9661 ggtaaaaagt gagctgccca gcaattcacg tccgttatac gaagtactga tgaccggcgt
     9721 tccagcctat gaaaatggca tctatagtaa ttaccatgct cagcgatcca aagagtggtc
     9781 gctgtttgaa ttagttaagg aagctggcgg aaaaacagga gccgccgctt accactggta
     9841 cagcgagttg tacaatcaag ccccctataa tcgtttggtt gatcgcatcc agcatcagga
     9901 ggagcgactg attcagcatg gcatctttta tagtgaggac acttaccctg attcgcattt
     9961 atttgcggat gcccattatt tagtgaatca gtatcagcca gactttttgg tcgtacattc
    10021 gatgaatatt gatgatgtcg gtcacaaatt taccgccgat tctcatgaat atgcagcagc
    10081 ggttaatcag gcggacagat tattggctat ttaccttcct gaatggctgc aaaaaggtta
    10141 tcaagtcgtg gtgactgcgg atcacgggat ggatgcgcac ggactgcatg gcggcagctt
    10201 ggctgcacat cgtgaagttc ctttttattt gatttcaaat aaacgccaaa agctgaagga
    10261 acaaactgta ccacagctgc tggcggctcc attgttttgc tggttattag gaattgcacc
    10321 gtcagagaaa atgcaggaca ttcaagaatt gatgagggga tgaaagagat gaaaaaacgc
    10381 ttggttctgg ttcctgcctc ctttatcttc tgtgcatttt tactgctgcc gctgcttttt
    10441 atggttctgt gcagcttgca cagtgattta actaaccagt ggacattggc caattacagt
    10501 gatattttca gcaacaaata ttacacacag gcctttgtta acagcgtact gattgctgtc
    10561 agctccagtg tgattgggtt aatcgggacg tttattttat gtttatgctt aatgaatcta
    10621 tcgactaaat tgcaggagaa aatcaccttt gtttccaatt tggcagctaa ttttgctggg
    10681 attccgctgg cattctcttt tattattttg ttggggaatg taggtgtgct gaaaatgatt
    10741 ttgccatttc tagcggactt caatttgtat tcttggtggg gattgaccat cacgtatacc
    10801 tatttccaaa ttccgttagg ggtcttgttt ttgtatccca gcatgaagga agtgaaaaag
    10861 gaatggctgg agtccgcaca attgctgggc gcttcatcag cgtatgcttg gttcaaggtg
    10921 gctttgcctt ttttgcgacc atcgattgcc agcacctttg tcatcttatt tgctaatggc
    10981 atggggacct atgaaacagc gtatgccctg accagcagta atgtaaatct tttaacgatt
    11041 cgaattgcgg ctttagtgtc gggagatgtg ttcgccaagc ctaatttagg cagtgcgttg
    11101 gcagtcgctt taggtgtcct gctggtaacg gcaatgttga ttattcaaaa gaaaggcaag
    11161 gtggtgcaga cgtgaaaaag ttaataaaac cgattttgtt ctgctttgtc ctgtattact
    11221 tgctgccgat tattggaacg attttgtatg ccagctccac taaatggtca aaatcgcttt
    11281 tacctagtga ttttaccttg caatggttcc aacagctgct gacggacagg gaatttattg
    11341 ctgcggtggg tcgctcactt ttattagcag gtgtggtctt ggtgacgatt ctgttgttga
    11401 tgattcccac cattatttgg attcatttgt atttccctcg tttgaatcgt tggctggaaa
    11461 agctgctcct gctgccgtat gctttaccag gagtgatttt ggtaacggct ttgcttcgaa
    11521 cgtatgctga aactggtatc ccaatgtttg tagtgttggt aggtgcattg tttattacgg
    11581 cgttgccgat tgtctatctt agtcttaaca accagatgcg cttaattaat ctgaaggaat
    11641 tagtggatgc agcagaaacc ttgggcgccc cgatgtctac gattattatc caggtgctgt
    11701 ttccaaacat ccgtatcggt gtgaccctag tttctctgat gattttttct tcggtttttg
    11761 gggagtacat gctgacgaac ctgttgattg gcggtcgatt tcagacggta cgcatctata
    11821 tgctgcggcg gatgaacgaa aacggccatt tggctagcgc tgtgatggtt ttgtatttgc
    11881 tgtttatggt gggaattgct ttaactacct ttatgctgac ttatcgacaa aagcaacagc
    11941 tgtcccttaa gcagacgagg gaagagaagc agtcgaaaaa gaagccctta aaggagttgt
    12001 gacggaaaat gtttttagaa atacatgatc tcaatctgtt ttttgatgaa aaacagattt
    12061 tagctattga tgaaattcag attgaaaagg gtgagctggt tactttacta ggtcccagcg
    12121 ggtgcggaaa gtctacgttg ctgcgctgta tcacgggatt ggaacaacca aagagcggtg
    12181 agattgtgct ggacaatgag aatattgccg ataagcctac gaaggatcgc aatatcggct
    12241 ttgtttttca acagtatgca ttgtttccaa ctatgactgt ttttgaaaat gtagcctttg
    12301 gtttgaaggt aaagaagctg agtcctgagg tgattcagga aaaggttttt gagatgctat
    12361 cattggtgga tatgacggag caggcagata aaaatgtcca gtttctttct ggcggtcaac
    12421 gacaacgggt ggcactggct cgctcattgg tcactgaacc gaaagtcctg ctgctggatg
    12481 agccattaag tgctttggat gcccgaatta gaaaacagct gcagcgggat ttgcgcgcta
    12541 tccagcaatc gctagggatg acgatgattt ttgtgactca tgaccaagaa gaggcgatgc
    12601 gaatcagtga tcggattttt gtgatggaag ctgggcgggt ggctcaggtt tccacctcga
    12661 aggaattgta tcagaatcct cagagccgat ttgttgcgga atttatcggc aactataatc
    12721 gtttcgaatg gtatgagctg aatcagtata cccacgagtt ttccgctaag ggcaatcgct
    12781 gcatttatta tttaagaccg gagctgattc aatttgaacc ggttcctcag ggggttaaga
    12841 ttccggttct atggaaggaa tcatttattt taggcaacat tcaacggtat gtttttcaaa
    12901 cgctggaggg caaagaaatt ttagtggatc ggttgaacga tcgggaagag aaaattagcg
    12961 atgccttata cattcagctg aaagatattc tagcaatccc tgtggaaatt gatactcagc
    13021 attttgcaca acaaagctag tgtatagtcg gcaaacattt
//
LOCUS       DAXLPY010000065        12940 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.065, whole genome shotgun sequence.
ACCESSION   DAXLPY010000065 DAXLPY010000000
VERSION     DAXLPY010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.065"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            131..3658
                     /locus_tag="ACF3UF_002124"
     CDS             131..3658
                     /locus_tag="ACF3UF_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFD3672209.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3655..7377
                     /gene="addA"
                     /locus_tag="ACF3UF_002125"
     CDS             3655..7377
                     /gene="addA"
                     /locus_tag="ACF3UF_002125"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFD3672210.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7446..7787
                     /locus_tag="ACF3UF_002126"
     CDS             7446..7787
                     /locus_tag="ACF3UF_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFD3672211.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8096..9139
                     /gene="pheS"
                     /locus_tag="ACF3UF_002127"
     CDS             8096..9139
                     /gene="pheS"
                     /locus_tag="ACF3UF_002127"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFD3672212.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9144..11564
                     /gene="pheT"
                     /locus_tag="ACF3UF_002128"
     CDS             9144..11564
                     /gene="pheT"
                     /locus_tag="ACF3UF_002128"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFD3672213.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="ACF3UF_002129"
     CDS             complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="ACF3UF_002129"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFD3672214.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
BASE COUNT         4398 a         2247 c         2741 g         3554 t
ORIGIN      
        1 tttgcgtata cttaaaaaag tagaaatatc agaaccttaa aaggatataa tttgaagaat
       61 atagaacaaa tgttcagtat tttttgatat aataaaggag caccgtatca tgtgttgaag
      121 gaggaaaagc atgtctttac aatttattct tggaaacggg aaaaaagatc accgtcaagt
      181 cttgatcgac gaagcatccg cttggctcga ccaggatgca agtaaccaag tatttttcct
      241 tgttcccaac tacagcaaat tcgaacagga acaagaaatt ttagcggaga tgcgaagaag
      301 aagcggaaaa aaaactttca gcacaacaaa cgttcaagta tttagttttt atcgtctggc
      361 ttggtatttg ctgcaacaga caactcttct tacaggaaat gaattatcag aatcaggatc
      421 tgcaatgatc ttgcgacaga ttttagaaaa aaatgaggaa gaattaacaa tctttcgcgg
      481 agaaatcaat aaaagagggt ttattcgtca attacaagaa ctctacagtg aattgcgtac
      541 aggaaatatt caaccagaag acctgatgct tttatttggt gattcaccta atgcagaaga
      601 ccagcaactt aaaatgaaag acttgaagct gattttttca gcttatgaca gcgaattgac
      661 tcaacgtgca ctaacaaatg aagatgcact atctatacta gcaaattata tgcagacaca
      721 agatttcaac aacgtcaaat ttattgtcag tggtttttct cgaatcaatg gtcaagagta
      781 tcaattactg caggcaatga tggaaaaggg gcaattggtt gtcgatttat tgctggatcg
      841 tccttataca gcggatcttc cagaagtact tacgctcttt catgagactg gaaagcttta
      901 tttccgtctt tttcaaagtg caagagaacg gaaagtccct atattagtgg accgatttgc
      961 accagagcag actcgtccga cagagcttca actgctgcaa acaatgtggg aagagacatc
     1021 tagccaaaag aaagcggcag tacacaaaat agggggacaa gagcatctcc atttgtggga
     1081 agctgaaaat ccaactgaag aagtccgaca attagctgtt gaaatcagac gactagtcag
     1141 tgaagaaaac taccgttatc gtgatatcca agtgctgaca aaaaatatgt ctttatatgg
     1201 aaatatcctt cggccgatct ttcaagaaat ggcaattcct ttttatatcg atgaagaaca
     1261 aatgatggaa aatcatccgc tgatcgaatg gatcaacagt ctgttcgctc ttgaccgcta
     1321 ttcttatcgg ctaagtgata ttatgcgttt tttcaaaact gaattatttc tgtcgacgga
     1381 agcagaaacc gaacttgatg aatggaaaca agagcgagat gaattcagga aaaaactgga
     1441 catcactgaa aatgtagcac ttgcttacaa ttatcaagga acttattgga ctcgtgaaaa
     1501 agactggcag tttgtggcgt atgattttga agcagaacag attgaagacg tacagtattt
     1561 ggaagaacag tcaaatacga ttagacgatt atttcagaaa gctgtaccag tatttttgaa
     1621 aaaaataaag aaaagcaaaa caggacaaga ggccgcaaat gttttttatc aatttttgat
     1681 ccaaagtggc gtacagcaac aattattgtt ttggcgtaat caggaagtag acagaggaaa
     1741 cttagaagcg gcaagaaacc atgagcagac atggggagcg ctgattgatc tgttggatga
     1801 atatgtagta atttatggtg aatcggcttt tgactggtca ctgttccaag aaatcattac
     1861 aagtggtcta gaaaatctaa gttatggtaa aatccctacc gcaatcgacc aagtgcgaat
     1921 caatcgtttg gaattagttc gaccaaatca agctgccgtc acttttgcat tagggttgaa
     1981 tgatcaagtg tttccagacc gaaaagagac aaaaggattg ttgtccagtg aagaacgaga
     2041 agtattaaat caggccttgc cagatggaca gtttttattc gacccatcaa aggaaagtat
     2101 ctcttttgag cctttccaag cctatcttgt ttttctttcc ggaacagatc gattatatct
     2161 tagttatgca caaagctatg acacagatgg ttcgctgaag atgtctcctt atttgcgtag
     2221 aatcacagaa tatttatctg ttcccgtcga gagaaaagag catttgacga tcgaaagcga
     2281 ccctaattgt tatgtaggga cttacagaag cggaatcaat acagtcaata ggatttatcg
     2341 attagcttta gatgaaaaaa aacctgtacc aaagcactgg caaaagctca aagaattagt
     2401 actgaattcg tcatggcgaa attttgcttt acagattttt gaaagtcagg aacatttaaa
     2461 tgttcctgtt tcgatgccag aaaaaatggc ggaagagctt tatggaaaag agatttatac
     2521 ttcaatttca cgtatggaga atttttataa ttgtgaatac aaatacttca tgcaatttgg
     2581 tttgaaattg aaagaacgaa ctgtttatgg tctaactcca gcagcaactg gtgattttta
     2641 tcatgaatca ttggatcgtt tcttcaagct actgttttca aaccaattat ccttagtgaa
     2701 tatgtccgat gcgcagcgta gagactttac tgaaaaagtg ctgcaggaag tattcggaga
     2761 acttcggttt gagatattgg atagttctgc aagaatgaac tatatccgct accagttagg
     2821 acagacgatt caaaaagtga catgggcttt gcaaaaacag agcaaaaata caggcatgca
     2881 tcctcttcag acagagattc tatttggtca gattgctgga gcaaaaggta tcacaggtct
     2941 ggaattaccg ttgagtaatg gtggaaaact ccatgttcga gggaaaatcg atcgaatcga
     3001 tgtagcttct gaacaagaag atacttggct aagcgtcgtt gattacaaat ctagcggacg
     3061 ttcattcgat gtcacagaag cttattatgg catggctatg caattattga cgtatctgga
     3121 cgtagcattg atggatgcgg tacgtttgac tggaaaggcg gctgttaaac cagcaggatc
     3181 atattattta catgttcata atcctgtatt gacggagaca gatgatgtag agaagaatac
     3241 attgaaaaaa tttagttatg atggcgtttt tgtcgatgat cccgctcttt tagaagtact
     3301 agatcattca ctggaagcaa aagaacaatc actgatctat ccagtgaaaa aaaatgcgaa
     3361 agatgaatac caaaaaggta gtttcagtaa agacaaattt ttcacggaag aagaactgca
     3421 actattcatg gcgcataatc gggaaaatat gcggttagct ggagatgcga ttacttccgg
     3481 agaaatcaaa ctaaatccag cttataaaga taaacagcgg attgcctgcg aattttgtcc
     3541 attcagaagc atctgtacgt ttgatgtgat gctgaaagaa aataattacc accgtctgga
     3601 gaaaatagat aaggaagaag cactgcgtag aatattgaaa aggagtgaag aagagtgaat
     3661 caaattcctt taaaaccgca aaatgaacga ttcacagatg atcagtggca agcgattttt
     3721 gatcaaggag ataatctatt agtctctgcg tctgccggat caggtaaaac tacagtgctt
     3781 gttcgaagag tgattgaaaa actaaaaatg ggttttgata tcgatgaatt attgattgtg
     3841 acatttactg aagctgccgc aagagaaatg aaagaaagaa ttcaagaggc attacaagaa
     3901 tccgtcaata gcgaaagtga ccctgtacgt agacagcatt ttactaagca gttagtttta
     3961 ttgcccacag cgaatatctc aaccttacat gctttttgcc tgacagttat tcgacgttat
     4021 tattacttaa ttgatattga tccagtcttt cgcatgttaa cagatgaaac agaaacgatc
     4081 ttgatgaagg aggatgtgtg ggacgagctg agagaagcac tttatgcaga aaatgatgaa
     4141 cgatttttcc aattaacaat gaatttttct aatgatcgtt cagatgacgg cttgacgaat
     4201 ctggtgtttt ctctttatga gtttgcccgt gccaaccctg acccccaaaa atggctagaa
     4261 cagttaagcg ataattatcg tttgcctgag gggctagcga aatctcgatt atatcaaaaa
     4321 caaatccgtc ctttagtttt ggcagatata taccaatgtg tacagttata tgaacagatg
     4381 actcagttag cacaaggtga aggattagaa aaaatgcatg agcaagtagc tggagaacaa
     4441 cagcagatca agaatatcta tgaagcgttc tcgcaagatc ggttagaaga agcttatgct
     4501 ggtttggaac aactaacttt ttcaactttt aagagcagtc ggaaagcaga attgaaagaa
     4561 atttccaatg aagtcaaggg catgagggat aaagcaaaaa aactgattca gcagataagt
     4621 aaaagttatt ttcctgtttc cccaagccaa atggaagaat taacggacaa agcactaccg
     4681 ttagtcgaag aaatgacaaa agtcacgcaa agcttcatgg acggtttcag tatgcgtaaa
     4741 cgggaaaaag gtgtgctgga tttcaatgat ctggaacatt tagcgttgca gattctcaca
     4801 gaaaaaacga aagatgtatg gctgccaagt gaagcttcaa aacattatcg aaaaaaattc
     4861 aaagaagtaa tggtagatga atatcaagac gtgaaccaat tacaagaagc cattttatac
     4921 tggctaagag aacccgatga tacaaaagga aatatgttca tggttgggga tgtcaaacaa
     4981 tccatctatt ctttccgttt agcagatcct agtttattta tcgggaaata cgagaatttc
     5041 tcaaagaaag aaggcggacg tcgaatcgtt ttggctgaga acttccgctc tagaaaagaa
     5101 gtcctttctt ttacgaatct tatttttgaa caactaatgg atccagcagt gggtcaaatc
     5161 aattatgacg aagcagccaa actgatccaa ggattttcag actttccaga gaatgaacag
     5221 tttgagccgg aaatcatgat ctatgaaaaa gaacaggaag aatcagagat tgagattccg
     5281 acggatgata tactggaaga caaaacagaa ggcgaacttt ttatgacagg actaaaaatt
     5341 cgtcaattaa ttgattcctc ctttatgatt tatgataaaa aatcaaaaaa aagtcgtccg
     5401 atagagtaca aagacattgt tctcttgaca cctacaaaga agaacaactt aacgatttta
     5461 gagattttca aaacattgga tattccatta gagatgaatg atgctcaaaa ctattttcaa
     5521 gcgacagaaa ttcgcacgat gatctcgctg ctacaattaa tcgataatcc ctatcaagat
     5581 attccgcttg cggctgtatt gcgctcaccg atcgtgggtc tgattgaacc agaattagcc
     5641 agcattcgat tagctaaccg tgcacatact tactatgatg ctgtgcttgc ttatcaagca
     5701 tcaaacgaag atgaattagc agctaagctg gaacattttg gcaagcaact agagcattgg
     5761 cgagaacttg ctcgccgttc ttcgatcact gacttgttat gggatatcta ttatgagacg
     5821 ggatatctag agtatgtggt cggtctgcca gcaggggcac agagacaagc caatctttat
     5881 gcattggttg atcgtgccaa agcttacgag caaagttctt tcagaggatt ataccagttc
     5941 gtgcgtttca ttgaaaaaat gcaagaaaaa gataaagact tagcagaacc agtcatttca
     6001 atagaagata atgctgttcg cgttatgacg atccatgcaa gtaaaggctt ggaattccca
     6061 gttgtatttt tgttagatat gacaaaggag ttcaacttac aagacttgcg caatcggtat
     6121 gcttttgaag aaaaacttgg agcaggaatt cgctatatgg atcctgaaac acgagtgtta
     6181 tatgatacgt taccgtttca agccatcaaa ttggcaaagc aaaacaaatt gttgtcggaa
     6241 gaaatgcgta aattgtatgt aggattgact cgggcagaac aaaagctttt cattgtcggt
     6301 tcctataaaa ataaagagca aatgatccaa acgtggtctg aagcagctga tcatgaggag
     6361 ttagtttttg atcctgcgct acgtttgaag ggcagaagca gcttgatgaa ttggattggt
     6421 tacggattga tccgtcatcc tgaaatgcag aaatacttag aggaagaaat ttcgacttct
     6481 cttcttcaac attcaaatgc acagttttct atttcatgga tgaatcagca atcgatcatt
     6541 gaacaaagac agttgcttgc tgaaaaagaa ctggttaact tagatcagca gatgaaagaa
     6601 gatgaaactt tattagcaga ttcgttacaa aaacgtctgg catatgaata tccttatcaa
     6661 gcttcttcac aaaccacaag ttatcaatct gtatctgaaa tcaaacgatt attcgaagat
     6721 ccagatgata cacaagaatc acgtttgact ctggaaagca gtcagaacaa agcagcatcc
     6781 cgtcaatttc gttatacgca agaacaacta gcagaaccaa aatttttgca aaaagatcgg
     6841 caagtgtcag cagctgctgt tggaactgct acgcatgctt tgttacaatt actgccatta
     6901 gagatgccaa ctacagagag tatccatcaa aaattacagg aattggtaag gaaacggtta
     6961 gtagacgaaa aagtcgcgaa aaaagtagat gtttcttcta ttatatggtt ctttcaaaca
     7021 gaacttggtc aacagctgat tgccaacaaa gaaaacgtaa aacgagaaca acctttttcc
     7081 atgctgcttc ctgctgacga agtatttcaa gactatccaa atcaagaaga tgaactatta
     7141 atccacggaa tcgtcgatgg atacctagaa gaaaaagatc atctcaatat ctatgatttt
     7201 aaaacagatt ttattttaca tccggatgat ccagcagaaa tagatgcaat cgtccaaaaa
     7261 tatcaaggac agctaagact ttaccaacaa gcaatgtcag aagctttgaa taagccagta
     7321 gaaaatgttt tcctaatttt gcttcgagtg aaacaaatta taaacattaa caaataatta
     7381 taattgagca aacttgactt atgttttgta aggattatgc tatactctgg gaagaggtga
     7441 gtatgatgga gctaacacag acagaattcg ttttatgccc taaatttgaa aaaacattct
     7501 ctattttagg aaaaaaatgg aacggattga ttatcgatgt actactcgaa aacggtccgc
     7561 aacgctttgt tgagcttgcg gcaaaaatcc cgatggtcag tgatcgagta ttagtcgaac
     7621 gcttgaagga attagaaaaa gaaggaatag tcactcgaaa ctttgcctgt agcgaaaaga
     7681 gccgttcaga atatctcttg actgaaaaag gagcagactt gcaaaaagcg atgcgtcaaa
     7741 tacaagtttg gagcgaaaaa tggatcacag aggaagaatg cggttgattt tgtaaaaaaa
     7801 atcttgtaaa ctatagtcca tacgaataag taaagaacga tgacgaaaaa gagtagtttg
     7861 gctaaaccag ttcagggaga tctgtcgcag actgaaagca gatcctgtgt ttgaaaaatg
     7921 aagttcactt tccgagttcg tctgataaaa tcagaccggc aattgtcgtt aacgaagtaa
     7981 gagtgcggtg taagtcattt atccgcaaat taggatggta acgcgaagac ctcgttcctt
     8041 aacaggaatg aggtcttttt gttttgtatt tggaatttaa aggaggaaca agcacatgtc
     8101 tctacaagca caattagaga gcttgaaaga agcaacgctc gtcaaaatca cagcggcaca
     8161 agatttaaat gaattaaatc aaatacgtgt tgaaacgtta ggaaaaaaag gaccgatcac
     8221 agaagtatta cgtgggatga aagatctaag tccagaagag cgaccaaaag tcggaagttt
     8281 cgcaaatgag atccgagatc ttttgacaga agagatcgtg cgaaaaaaac aagtattaga
     8341 agaagaagcg ttaaatgcag ctttggcaaa agaaacaata gacgtgacac tacctggtag
     8401 aaaagtaaaa catggtacac gtcatatcgt gacacaaatc atggaagaaa ttgaagatat
     8461 ttttgtgggt atgggctatc agatcgtaga aggatatgaa gtagaatctg atcattacaa
     8521 tttcgaacgg atgaatctgc caaaagatca tccagcaagg gacatgcaag atactttcta
     8581 tatttcagac gagatattga ttcggacaca tacttcacca gtccaagcac ggacaatgga
     8641 aaaacatgat ttctctaagg gtgctctacg aatgatctcg ccagggaaag tcttccgcag
     8701 agatacagat gatgcgaccc acagtcatca gttccatcaa attgaagggc tagttgttga
     8761 taaaaacatc acaatgggcg accttaaagg aacattagaa gtcgtaatga aaaaaatgtt
     8821 tggggaagat cgtgaaattc gtttgcgtcc aagttatttc ccatttacgg aaccatcagt
     8881 agaagtagat gtcagctgtt tcaaatgtgg tggtgccggt tgtaacgtat gtaaatacac
     8941 tggatggatc gaaattttag gagctggcat ggtacacccg aatgtgttga agatgtcagg
     9001 aatcgatcca gaagaatatt caggctttgc tttcggcctt ggaccagacc gcgtagctat
     9061 gttgcggtat ggagtgaatg atatccgtaa tttctatcaa aatgacttac gtttcttaag
     9121 tcagttcaag ggggagtaag aaaatgttag tttcatataa atggctcaat cgttatgtag
     9181 atttatcgaa tgtaacacca aaagaattag cggataagat gtctgtgaca ggaatcgaag
     9241 tagagggagt aacggttcca gaagaaggct tgaaaaaaat cgttgtcggt gaagtcaagg
     9301 aatgcgtacc acatccagat tctgatcacc tttctatttg tcaagtcgat attggcgaag
     9361 acgaactgtc tcaaatcgtt tgtggagcgc ctaatgtgaa ggttggaatc aaagtgattg
     9421 ttgcacttcc taactcacgt atcgctggta atgtaaaaat caaaaaagga aaaatgcgtg
     9481 gccaagtatc aaatggcatg atttgctcat tacaagaaat tggctattca gatagtgtta
     9541 taccgaaaga atacgctgaa ggtatctatt atatgccaca agaagctgta aatggcgatc
     9601 cagtttttcc ttatttggat atggatgatt cgattattga attatctatc acaccgaatc
     9661 gtgcggatgc attgtcaatg cgtggcgtag cttatgaagt tggggcaatt tatcgtcaga
     9721 ctcctacatt cgatgacgaa aagctggtag aatcctcacg tcctgctagc gataaaattc
     9781 aagtggaagt tgaagataaa gaagcagttc ctgcttatca aatcagaatc attgaaggag
     9841 taagaatcca gccaagtcct caatggctgc aaaatctttt gatgaacgaa ggcattcgtc
     9901 caatcaacaa tgtagtagat gtgacgaact atattttgct tttattcgga caaccactac
     9961 atgcatttga ctacgacaaa ttgaaatcaa aagagatctt tgtccgccgt gcaaaagaaa
    10021 atgaaacatt agtaacacta gatggagaat ctcgggaatt gacaactgac aatctcgtca
    10081 ttactaacgg caaagaacca gttgctttag ctggtgtcat gggagggtta gactcagaga
    10141 tcacgaatga aacaacaaca gttgcactag aatctgcttt atttgatcca atttcgattc
    10201 gtcgtacagc aaaacaattt aatttgcgta gtgaatcctc tgcacgtttt gaaaaaggaa
    10261 tcaaccatgc gactgttgga gaagccagtg aggttgctgc agcaatgatc gtttctcttg
    10321 cgggtgggga agttctacaa ggcgcggtca aaggctcaga gatcaaagca gaagacgtat
    10381 cagtgaagat ttcacttgaa cgcatcaatc aatatttagg aacatctctt gtcgttaaag
    10441 aagtaaatga gatttttgaa gcacttggat ttagctatga agaaaaggag tatgtttatt
    10501 ccgtagtagt accaccaaga cgctgggata tccaaatcga agcagatatt atcgaagaag
    10561 ttgctcgtat ttatggatac gaccagttgc catctacact tccaagtgga gaaacggttg
    10621 ctggaagctt gtcaaaagaa caagaaacta ctcgtaaaat tcgtacaatc tttgaaggaa
    10681 gcggattgag cgaagcaatc agttatgcat tgacaacaga agaaaaatca agacagtttg
    10741 ttataaatga aagtaatatt acacgtttgg actggccaat gagcgaagaa cgttctgtat
    10801 tacgaatgaa tttgatcagc ggactattag atgatatcag ttataacact gcccgaaaaa
    10861 atacagagat tgctttatat gaaattggtc gggtgttctt ccaagaaaat gatccacgta
    10921 cacatctgcc gcaagaagta aaacatgcag caatcgctat ttctggtatt tgggaagaaa
    10981 aagattggca gacgaaagct caaaatgtag actttttcac catcaagggt cttttagaaa
    11041 acttatttga acaactaggc atcactgaag atgtccatta tcaaacagtg acagaaatga
    11101 aggaaatgca tcctggaaga actgctgcga tttaccttgg cgaaaaattt attggttttg
    11161 tcggtcaagt gcatccaacg attacaaaaa gttatgatat tccagaaaca tatgttgctg
    11221 agtttgattt atctgctata gtggaagctg ctcaaaaagg gatcgttttc gaagcagtga
    11281 caaaattccc agcagtcagc cgggacatcg ctttgcttgt aaaagaaact gtgacaaatc
    11341 aggaattaac agaagttatc cgttctgctg ccggaagatt tttaacagat atccaattat
    11401 ttgatgtcta tcaaggagaa aacattgaaa aaggacataa atccatggcg tatagcctga
    11461 cattcgtcaa cccagaagca acattgacag atgaagaaat caataaagca atggaaaaag
    11521 tcgaaaaagc gttggtagaa aacctagagg caagtattcg ctaagaagga aaatatagta
    11581 agtaacgatc aagtagcttt tgaagaccat acatttgaaa aaaagatgtg acacaacttc
    11641 gtcacatctc tttttttgat tttaaaaaag gaatagcaca gagacgagat aaaaaaacag
    11701 gcctttacag cctgcttttt tagagtaaat gaattaatgg aagtaattga ttcccattgc
    11761 tgattttact tcagaaagtg tttgtgcagc tactttagca gcttcttcac tacctttacg
    11821 taagatttcc ataacagctg aaggatcttt ttccaattct tctcggcgcg cacggatcgg
    11881 tgcaaattca gcttccaata catcaatgag gtatcgtttg atctttacat caccaagtcc
    11941 gccgcggcgg taatgagctt tcatttcttc aattgcttct ttatctgttc cgaatacatc
    12001 caagtaggtg aagaccatat tcccttctac ttgtccagga tcttgtacat ggatgtggtt
    12061 tggatcagta tacatactca tgactttttt ctgtaagaca tcggcaggat cggagatata
    12121 aataccgttt cctaacgatt tactcatttt gccatttcca tcgattccag gtaatctacc
    12181 cattcctttt ggtgggaata cgccttttgg ttccaccaag acttcaccat atgtatgatt
    12241 gaagctttgt acgatttcct gtgtctgctc tagcattggt ttttgatcct caccaacagg
    12301 tacaagattc gctttgaatg cagtgatatc tgctgcttga gaaacaggat agataaagaa
    12361 tcctgtaggc acgctttcac cgaatttttt ttgttcgatt tctgttttga cagtcggatt
    12421 gcgccgaacg cgtcctacgc tgactaagtt caaataatac atggttaatt cagctaattc
    12481 cggaatttgt gattggataa ataaagtaga ttttgcagga tctaatccca cggctaaata
    12541 gtctaaagca acttgcaaga catttgatga aaccttctca ggatttttag cattatctgt
    12601 cagtgcttgc atgtcagcaa tcatgacaaa cagttggttg tcttcatctg cctgcatagc
    12661 cactcgggtt tttagagaac cgacgtaatg ccctaaatgc agcttcccag ttggtcgatc
    12721 tcccgttaaa ataatatttt tcaaaaaaga cacctcttta cgatttgtaa gtctgagcac
    12781 ttaatatctt accgtttttc ctgaaaagaa acaacagttc ctaaggaaaa aacaaggaaa
    12841 gaggataaaa taactaatag attagaaatg gaagaaatat ttatgggaga ataaacgttc
    12901 taagaaactt tacaaattac taaactatca gatataatgt
//
LOCUS       DAXLPY010000066        12519 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.066, whole genome shotgun sequence.
ACCESSION   DAXLPY010000066 DAXLPY010000000
VERSION     DAXLPY010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.066"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            18..755
                     /locus_tag="ACF3UF_002130"
     CDS             18..755
                     /locus_tag="ACF3UF_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3672215.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            769..1584
                     /locus_tag="ACF3UF_002131"
     CDS             769..1584
                     /locus_tag="ACF3UF_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFD3672216.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            1597..2244
                     /locus_tag="ACF3UF_002132"
     CDS             1597..2244
                     /locus_tag="ACF3UF_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3672217.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            2260..2916
                     /locus_tag="ACF3UF_002133"
     CDS             2260..2916
                     /locus_tag="ACF3UF_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3672218.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            3078..3899
                     /gene="racE"
                     /locus_tag="ACF3UF_002134"
     CDS             3078..3899
                     /gene="racE"
                     /locus_tag="ACF3UF_002134"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFD3672219.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            3902..5257
                     /gene="rph"
                     /locus_tag="ACF3UF_002135"
     CDS             3902..5257
                     /gene="rph"
                     /locus_tag="ACF3UF_002135"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFD3672220.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            5258..5776
                     /locus_tag="ACF3UF_002136"
     CDS             5258..5776
                     /locus_tag="ACF3UF_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3672221.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            5883..6383
                     /gene="cbpB"
                     /locus_tag="ACF3UF_002137"
     CDS             5883..6383
                     /gene="cbpB"
                     /locus_tag="ACF3UF_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFD3672222.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(6663..7583)
                     /locus_tag="ACF3UF_002138"
     CDS             complement(6663..7583)
                     /locus_tag="ACF3UF_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFD3672223.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            7709..8761
                     /locus_tag="ACF3UF_002139"
     CDS             7709..8761
                     /locus_tag="ACF3UF_002139"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFD3672224.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(8871..9626)
                     /gene="fabI"
                     /locus_tag="ACF3UF_002140"
     CDS             complement(8871..9626)
                     /gene="fabI"
                     /locus_tag="ACF3UF_002140"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFD3672225.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            9846..10286
                     /gene="fabZ"
                     /locus_tag="ACF3UF_002141"
     CDS             9846..10286
                     /gene="fabZ"
                     /locus_tag="ACF3UF_002141"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFD3672226.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(10401..11162)
                     /locus_tag="ACF3UF_002142"
     CDS             complement(10401..11162)
                     /locus_tag="ACF3UF_002142"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3672227.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            11351..12445
                     /locus_tag="ACF3UF_002143"
     CDS             11351..12445
                     /locus_tag="ACF3UF_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFD3672228.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         4031 a         2173 c         2641 g         3674 t
ORIGIN      
        1 aatgggagtg taattctatg gcaatgatta aatttgatca cgtggataaa tattatggca
       61 agttccacgc attaaaaaat atcaatctcg aattcgagaa aggagaagtt gtcgttgtca
      121 ttggtccttc tggttcagga aagagcacga tgcttcgctg tatcaatgga ttagagacga
      181 tctcttcagg taagctgctg attaatgata ctgacttgca tgataaaaag acaaaactga
      241 cagaagtccg aaaaaacatc ggcatggttt tccaacattt caatttgtac ccaaataaaa
      301 ctgttctgga aaacatcaaa ttagcaccaa tcaaagtgtt gaagcaagac caggcaactg
      361 cagtcaaaaa cgcggagaaa tttttgaaaa ctgtcaatat gttagataag aaagattctt
      421 atccttccat gttatccggg ggacaacagc aacgggtggc aatcgccaga ggtttagcga
      481 tgaatcctga gatgctgctg tttgatgaac ctacttctgc tttggatccg gaaatgattg
      541 gtgatgtatt agacgttatg aaaaaattgg ctcatgacgg tatgtcaatg attgtcgtga
      601 cacatgaaat gggctttgcc aaagaagtgg cggatcgtgt tatcttcatg gctgatggag
      661 aagtattgga agacagcaga aatgtgagag actttttcga aaatccaaat gaagtccgag
      721 cacagcaatt tatcagtaaa gttatcaatc attgatagga ggaaaaagat gcgcaggtta
      781 aaaaaaatac gcctgatttt ccttttaggc attgcttttc ttgcactagc cggatgtaaa
      841 ggaaatgggt tggcaaatga agatatttta gagcgaagca aatctaccaa tgaaatcatc
      901 tggggtgtca agtatgatac tcgattattt ggaatgatgg atattgagag cagaactgta
      961 caaggatttg atgtagatat tgcaaaagca atcactaaaa agatccttgg tgacaatgga
     1021 aaaacagaat ttgttgaagt cacttctaaa actcggattc cattattgaa aaacggaaat
     1081 atcgatgcaa ttattgcaac gatgacgatc acagatgaac gaaaaaaaca ggttgacttt
     1141 tcagatgtct atttcgatgc tggccaagct ttgttggtaa agaaaggaag ccaaatcaaa
     1201 agtgtagatg atttgaatgc ttctacaacg gttctagcag tcaaaggttc tacatcggct
     1261 gcgaatatcc gacagcatgc accagatgca aaaattttag aattagaaaa ctatgcagaa
     1321 gcatttactg ctttacaatc tggtcaggga gacgcgatga ctacggataa tgcgattttg
     1381 ttagggattg cagatgaaaa tccagagtat gagttagttg gtggaacgtt tactaatgag
     1441 ccttacggga ttgcgatcaa caaagggcaa gaaaacttct tgaaagctgt taaccaagcg
     1501 ctagaggaaa tgcatgcaga tggcacatac gataaaatct atcaaaaatg gtttccaaat
     1561 gaaactgaag gaaaagtaga gtaaggggga gaggcaatga gcgaattgat acaaacttat
     1621 ggaccaatct ttgtcgacgg gttcaagatc acattgtttt cgagtgtctt agcacttgtg
     1681 tttagtttga ttatcggaac gttaatggca atcttccaat tatcaaagaa taaagtagtg
     1741 agcgccttag caaaggcata tgtagaattt tttagaaaca ttccattatt aatcatcgtg
     1801 atgttttttt atgttgtcgt accgatttat tggtttaatc tagatggatt ccaagcaggt
     1861 acgattggat taacgatcta tacatctgct tttattgctg aaacagtacg ttcagggatt
     1921 caaaccgtac caaaaggtca aacagaagca ggactatctt ctggttttac ctattcagaa
     1981 atcatgcgtt atattgtttt accgcaagca ttcaaaatcg ttatcccgcc attaggcaac
     2041 caatttatca acctcgtaaa aaactcatct attttagcaa tcgtagctgg tttagatttg
     2101 atgtatcaag gagacttgat cgctagtgaa acattcaata ccttcgatac gtatatcatc
     2161 gttgggttat tttacttagt tatcacgcta ccgttatctt acttaatggt ttatcttgag
     2221 aaaaaatggg cggttcgttc atagaaggag gggaaataca tggattttag cggcgctttt
     2281 tcatggatga atatccgttt tttattggaa ggattaaagg ttactgttga agtttcattg
     2341 ttttcgatca tttttagttt cttgatcggt ggtctgacag gtgtgattcg ttttgcgaat
     2401 atccctttct tttccaaaat ccttggtgta gtgattgata ttatacggaa tcttccatta
     2461 ttattgatca ttttcttcac ttactttgcc ttacctcaaa tcggcattca gatgaacatc
     2521 ttctggtccg ctgtcgcagc attaacgatt tttgagtcag ctatgttgtc ggaaattttc
     2581 cgagctggac tcaatgctgt tccaaaagga cagatggaag caggattatc aacgggactg
     2641 acttatgtag aatcgatgcg aacgatcgtg ttaccgcaag catttaaatc aatgatcccg
     2701 gcaattgtga gccaattgat ttcactgatc aaagatactt cattagcagt aatcatttct
     2761 ttacctgaac tttctcatca ggcacgtatt atttatggac agaacaccaa ttatgtgctt
     2821 ccgatgttca tcatcatgac acttatgtac ttcgtggtat gttacgcgct ttctctgctt
     2881 tccggttact tggaaaagag acggtacagt tattaataga tgattctttt agcggttgtg
     2941 gcaaactaaa gtcacaaccg cttttcctct ttccattcga aaaaaagaga tttcgattgt
     3001 tttaagcaag taagagcact tgaaaattca cgctaaaaag tacacaatag ggaggataga
     3061 atttattgaa aaaaaggatg atacgattga cagataatcg ccctatcgga tttattgatt
     3121 caggtgtcgg cggcttgact gtagtaaaag aagccctgaa acaattaccg aatgaaaata
     3181 ttttatttgt aggagacaca gcacgctgcc catatggccc tagacccgcg gaacaggtaa
     3241 tccagtatac ttgggaaatg acggattatc tggtggagca aggaatcaag atgctggtga
     3301 tcgcctgcaa taccgcaact gcggtggctt tagaagaaat caaagctgct ctttctattc
     3361 cagtcatcgg tgtgatcctt cccggtacta gagcggcagt aaaaaaaaca caaaataaac
     3421 aagttggcat tatcggtacg attggtacgg taaaaagtca agcttatgaa aaagcactga
     3481 aagagaaagt accagaattg actgtgacaa gtcttgcttg tcccaaattt gtttcagttg
     3541 tcgaaagtaa tgaataccat tcatcggtgg cgaaaaaaat tgtggcagaa acattagctc
     3601 ctttaaccac taaaaaaatc gatacattga ttttgggatg cacccattat ccattattac
     3661 gccccatcat tcaaaatgta atgggagaaa atgttcaact gatcgattct ggagcagaaa
     3721 cagtaggtga agtatctatg ctgttagatt atttcaattt gagcaattca ccgcaaaatg
     3781 gtcggacatt atgccagttt tatacaactg gctctgccaa acttttcgag gaaatagctg
     3841 aagactggct tggaatcgga cacttaaatg tagaacatat cgaattggga ggaaaataag
     3901 gatgcgtcat gacgggagaa aagcccaaga gcttcgcaaa ctggagcttc aaacaaatgt
     3961 tttcaaatat ccagaaggat cggtagtgat ccgttttggt gatacaacag ttatttgttc
     4021 tgcaacaata gaaaattctg ttcccccttt tttgagagaa acaggaacag gatgggtgac
     4081 agcagaatat agtatgctgc ctcgagcaac gagtacgaga aatcgtagag aaagcagcaa
     4141 agggaaactt tctggtagaa caatggaaat ccagcgtctt attggtcgtt ccttgcgtgc
     4201 agtagtagac ttggaaaaat taggagaacg tagtatcatc gtagactgcg atgtgatcca
     4261 agcggatggc ggtactagaa cagcaagtat cactggggca tttgtggcat tgaaattagc
     4321 cattgaaaaa cttttaagag aaaaagaatt gtcagaagat ccaataaaag aacatcttgc
     4381 tgcagttagc gtaggaatct taccagatgg gacttgcgtc acagatttgg attaccaaga
     4441 agattccgca gcacttgtag acatgaatct tgtaatgaca gaatctggaa aattcgtgga
     4501 gattcaagga actggagaag aagcaacgtt tgatggtgaa cagttgaatg aaatgctctt
     4561 ttttggaaaa aacgcgattg aagatttgat caaagagcaa aaacatgctt tgctaacaga
     4621 gtttgctcaa aatgatgagc ggatagaaga aacaaaaaca atcatcattg cgacaagaaa
     4681 tccaggaaaa gcagaagagt ttcgaaatat gttcaaagaa gcgggatatc atgtaaaaac
     4741 attacttgac tatcctgaat tgccagatgt ggaagaaact ggcagcacat ttgaagaaaa
     4801 tgcccgatta aaagcagaaa cgattgcaca attgcttgat cagccagtct tagcagatga
     4861 ttcaggtttg aaagtggatg ctttaggcgg tatgccagga atctattctg cacgttttgc
     4921 aggggaacaa aaaagtgatg cggggaataa cgccaaatta ttatatgaat tgacagatgt
     4981 gccggatgaa aaaagaacag cacaattcca ttgtacgtta gtattcgcgg cacccaaaaa
     5041 agacagcctt gtagtagaag cggaatggcc cggtcgagta gcccgtatac catctggcga
     5101 aaatggcttt gggtatgatc ctttatttat cccagaaggt aagaaacaaa cagcagcaga
     5161 attatcgagc gaagaaaaaa acaagatcag tcatcgggct caagcaatga aaaaattgag
     5221 tgccgagtgg aaacaatggc tggaaggaga gagatagatg cggtatttag tagtaagtga
     5281 taatcatgga gacagagata tcctcgttga cttagtagat cgttatcgtt ctgaagtgga
     5341 tatctttttc cattgtggtg attcggaatt agaagcttct gacccattat gggatacatt
     5401 ccaagtggtt caaggtaatt gtgattatgg accaggattc gaacagaaaa aagtgatcca
     5461 aactggtcag gatacagtat tcatgactca cggtcattta tcgaatgtcc gatttggttt
     5521 gacacagtta gcaatcgaag ctcgagctgc aactgccgat atggtgtttt ttggtcatac
     5581 ccatcaaata ggctgtgaga tggatcagaa aatcctgttt ttgaatcctg gtagcatttc
     5641 tcagcctaga ggcccgatcc aaatcccatc atatgctctt atcgaaagtt tagatgacca
     5701 aatttctgtt caatactata accgtgccca tcaggcagtt gaagagttgg ccttttcttt
     5761 ttcgagagag cgctgaataa aaaaactcta atttttaata aaaataagct ttattttatg
     5821 aattttgcat ccggtttcgg taaaatagta gtgttgaatg aaatagaaat ggaggccatc
     5881 agatgattgg acctatagta agagaaatgc tgctggaaaa tcaggaaacg tttttgattc
     5941 ctgcagaaaa tgtggcaaat gttatgtatc atcatccatt gtcccatggt ttacttgtgt
     6001 tatcgaaggt cggttattcc aaaattcctg tattaggaaa agatgatcac tttgtaggac
     6061 tagtaagttt atcagatgtg gtcaataaaa tgattgactt gcaaacaatc agcatggacc
     6121 cgttagaagg actaacggtt gctgatgtga cagaaacaga tgttccgaca attgatgaaa
     6181 attgggaact agaagaagta ctccatttgt tagtcgattc gcctttttta ccggttgtca
     6241 cagaagatcg gattttcaaa ggaatcatta caagaaaaga gctgcttaaa gccgtaaact
     6301 tcatggtgca tgaattagaa cgtcgtaata tattgtctcc gaaaatcgaa gaattaaaag
     6361 aacaaatcga tatcgtgagc taaagaacga gaaactaaaa gataatcaaa aaataagtag
     6421 aaaaaacagc gtaccagttt tgactttatc ttgaaaaaga ggctgggaca aaagcgttta
     6481 actccaagaa ataagaagga attcacgaaa attgcttttc aaatttttgt gaatttcagc
     6541 ttatttccga aggagttgct tctgcttccg ccgtttatac gtgtttagag cgtgggacaa
     6601 aagtgttctt tacttttgtc ccacgctctt tttagtgaga ttcgttgcat cgtttgtcca
     6661 aattattttc cgacagcaat tggactgttc ggaatcgtga aaccagaagc tgtcaattct
     6721 ttgacatagg agctcaagaa ctcttctttt aaggcatatt gttttccgtt caatgcgtag
     6781 cagaccgtac gaatcgcaaa attgctgttt ccaagatcca ctaatccaaa gatagaaggt
     6841 tcagtttgga gctcttcttg gtatttttca gctaatgtac gatttactcg atcaatgatc
     6901 tcatagattt tgtcatatcc ttcttcagga acaatccgaa tatctaaaag tacttgcata
     6961 tttgcacgag agagattgct gatcgtggtg atgtttcgat tcgggatgaa atggacagta
     7021 ccatccgttg ctttcagctg aagggtacgg ataccaacag atacgacggt tccttcaatc
     7081 gttaagtttg ctagcttgat gtagtcccca acatccatct gttgttccat gataataaaa
     7141 aatccggtaa taacatcact catgaaccct tgggcaccaa gaccgattgc cacacctgca
     7201 attccggcac cagccaaaag tgatccgatc ggcacaccga tagcagataa aattgcatag
     7261 ataaaaaaga aaccaagggt ataatgaaaa atagtattta aaagactatg taaagtcttt
     7321 aagcggctct cgtttagaat ggctttttta gaatactgat taaaagactt atcaatcaga
     7381 tattttccca cacggtgaag aatccaaaaa aggacgatca aaaaaatcag atataaactt
     7441 ttttggataa aggcagccaa aatggcgtcc caatcaatcc cgtcccaaaa ccgctgaaac
     7501 gcatttactt tgctgacagc ttgatctgtc aatgtctcgc cagaagagtc tgtcgtaccg
     7561 gcagttgcta ataatgaaaa cataaaatcc tcttttctaa aatttgattc tttctgtatt
     7621 gtaccaagaa gttttcaaaa aaggaaatag caaaaataac tataatgaag gaaaaaagct
     7681 gaaaataaaa tgacaaataa tatggataat gataaaatgt ggagaaaata acgaaggtgg
     7741 taagtatatg caaatcgatt ggaacaatct aggtttttct tatatcaaaa ctccttggcg
     7801 ttttattgcc aaatggaaag acggacaatg ggaagaagga gaattgacag aagataatta
     7861 cctgacgatt catgaaggct ctccagcgct tcattatggt cagcaatgtt ttgaaggtct
     7921 aaaagcttat cgtcgaaaag acggcaaggt caatctcttt cgacctgaac aaaatagtcg
     7981 acggatgaat caaagtgcta gacgattgct gatgccaatg gtccctgaaa agatgttcgt
     8041 tgatgctgtc aagcaagtgg taaaagcaaa tgaagatttt gtgccgccct atggaacagg
     8101 cgctacatta tacttgcgcc ctttactgat tggggtcggt gaaaacattg gtgtccatcc
     8161 agctccagaa tatttatttg tcgtcttctg tacgccagta ggagcgtatt tcaaaggtgg
     8221 actaaaacca acgaatttta ttgtatctga ttacgatcgt gctgctccta aggggactgg
     8281 tgcagcaaaa gtcggcggaa attacgcagc gagtttactt ccaggaacag aagcaaaaga
     8341 actggattac tcagattgtg tttatcttga tccagccaca catacgaaaa tcgaagaagt
     8401 aggtgcagca aatttctttg gaattacaaa agacggaaaa ttcatcactc cgcaatcgcc
     8461 ctctatctta ccaagtatca cgaaatattc cttgttgcag ttagctgaag aacgactagg
     8521 actgcaagca attgaaggag atattttcat tgatgatcta gatcaatttg cagaagctgg
     8581 tgcatgtggt acagcggctg ttatttctcc aatcggtggg atttatcaca ataacaatct
     8641 tcatgtattt tatagtgaaa cggaagtagg accagtaaca aaacggttgt atgatgaatt
     8701 gacaggtatt caatttggag acatagaagc accagaaggc tggattgaag tcgtggaata
     8761 atttcaaagt aatgagttga aaaaaacgta aaaagaaaaa atcaggaaga gactttaaaa
     8821 agttttttcc tgatttttat atgttttact ttaaagaatg caacaaaagt ttatgaaaga
     8881 tggacacctt tgtcaacgta gataatatca ccgatgattc cgctggaaag tgggctgatt
     8941 aagaaagcac aagcattacc gacttcttcg atcgtcacac cttgctgatc aggcgtacga
     9001 gattcagata actggatcag tttttgatag tctttaacac ctgtgacagc taatgttttg
     9061 attgccccag ctgagattcc attgacccga attcctttag gcgagaactc agctgccaaa
     9121 taacggatag cagcttcaag agaagctttc gcaataccca tcatgttata attcgggatt
     9181 gcgcgttctg aacctagata agtcatgcta acgatcccgc tgtttggtgc aagaaacggt
     9241 tgtgcgtatt ttgatacagc aattaaagag tagctgctga tatcttgagc taattgatag
     9301 ccgtctctgg aaatatcaga cacatttccg gacaattctt ctttgttggc gtaagcaact
     9361 gcatggacaa ggccgtggat ctccccagca tattcaccga tggcattcat tgctttttcg
     9421 atgctttcgt cgctagaaac atcacattct acagtgaatg cttcttcgcc gaccaatttg
     9481 actaatgatt ttttcattcg ttcattttgg taagtataga taatttctgc cccttgtttc
     9541 aacattgctt cagcacaacc ccaagcaatg ctttttttgt tagcgacgcc cataatgacg
     9601 attttttttc cttctagaaa tgacataatg actctccttt gtttctgata aaaatttgat
     9661 agtcgtaaaa aaatagagaa taatagctaa aataacttct tgatttctta attattagtc
     9721 aaaatgtttt gattgtcaaa ctattttttc ttaaattaaa aaaagattgc taaatattta
     9781 ggaatatgat actttgatag tcaaagtaat gaaaatggca attgcctgaa agaaggagtt
     9841 taattatgtc ttacgtatta tctgctactg aagtaatgga attgattcct aatcgttatc
     9901 ctatttgtta tattgattat gtagatactt tagaaccagg aaaaaagatc gttgcgacaa
     9961 aaaatgtaac aatcaatgaa gattttttcc aaggtcactt tcctgacaat ccagtgatgc
    10021 cgggtgcgtt gattctagaa acactggcac aagcaggttc gatacttatc ctaaaatcag
    10081 aagagtttct aggaaaaaga gcttatatcg gtgggatcaa taaggccaaa ttccgtcaaa
    10141 aagttgttcc aggagatgtg ctgaaatgtc attttgaaat caccaaaatg aagggatcag
    10201 tcggtacagc gttatctgca gcatatgtag atgataaaaa agtctgtgag tgcgagttca
    10261 cgttcatcgt caaccaaaat gcttgactat aaaacctgat atagcaaaac aaaaggaagc
    10321 ttacttgctt tttatgtaaa aagaagacgc ctgaatccta gcatacgttg tcatctatgc
    10381 aggattcaga cgttattttt ttatttttgt tttgcttctt gcagtatatt gattttatcg
    10441 atttttactt cttcttttgg tttgtctgaa ctatctgttt cgatatttgc aatagcatcc
    10501 acgacatcca ttccttcaat cacttggccg aagacagtat aatggccatc tagtgaagga
    10561 taaccgccgt ttttataagc gtcgatgatt gcttgaggat agtcgtcttt taaaagacca
    10621 tcatgcatat catctgtatt ttgaacgata aagaactggc tgccgttact gttaggatct
    10681 tgtgagcgag ccatagataa cgcacctctt atattataaa ggtggttgtt gatctctgtt
    10741 tcaaatcctt ctccccaaat gctttcccct ccagtgccat cgcctttagg atcgccacct
    10801 tggatcatga aatctttgat gacgcgatgg aaagtcagtc cgttgtagta accgtctttt
    10861 gcatgtgtca taaagttttc aaccgctttt ggtgcgtgtt cgggaaataa tttgattttg
    10921 attgtgcctt tattcgtcac catttcgacc agatcttcat tttcggcgac atctttcgtc
    10981 aattgtggta attccaatgc gttcaaatcg acgctactgg cagtcgtgct ttccgcagta
    11041 gatgtacttt ttgaactttc tgtagacgaa ctagaagaag tcgtgttgtt tgcagaacaa
    11101 ccagcagcaa acagcaatgc tgctgctaaa ctaatactta aaataacttt atttttcttc
    11161 ataactgttc ctttccaatt tactattttg ttatctttaa tgataacaaa atagagggaa
    11221 aatacctact taaattattg gaatttatca tttattttaa aagaaaaaga aaaggtgtag
    11281 accatttact ttgtgtttgc tataatgtaa gtggatacaa aaacgaaaag atgcaggagg
    11341 aaatggtaat atgggaaaat taggaatctc gatttatcca gaacggtcaa catttgaaaa
    11401 ggacaaagcg tacttggatt tagctcataa gtatgggtat aaacgggttt ttaccagttt
    11461 gctgcagatc aatgatgata aagaaaaagt tctttcagaa tttaaagaag tagttgatta
    11521 cgcgaatagc ctaggcatgg aagtaatggt tgatatcaat ccagcgttat ttgaacagtt
    11581 ggagatttct tacgatgact tatctttttt ccataagatg ggtgcctacg gggtccgctt
    11641 agatatcgga ttcacaggag cagaagaagc aaaaatgacg cgcaatcctt ttggtatcaa
    11701 aatcgagatc aatatgagtt cgggcacgaa ttacgttgac aacatcatga gttattcgcc
    11761 aaacacggat aatttattag gttctcataa tttttatcct catcgatact ctggtttagg
    11821 atacgaacac tttgtttttt gttcagaaaa attcagaaaa tataatttga atacgatggc
    11881 attcgtcaat tcgcaatctg ctgagtttgg cccttggcct acgcaagatg gcttgtgcac
    11941 gctggaagac caccgagatc ttgaaattgc gacacaagtg aagcatttaa tccttacagg
    12001 attgattgat gatatttcta ttggaaatgc gtacgcaagt gaagaagaat tgaaagaaat
    12061 ggcagaagca tttaacgcgg attatccaac attgaaagta gatacggaag aaggtattac
    12121 agaaaacgaa cgaatctgct tgtttgataa ccttcatagt tatcgagggg atcgctcaga
    12181 atatatcctt cgttcaacga tgactcgtgt atactacaaa gataaagatt tcccgcctca
    12241 taatacgcga gatatgcatc atggggatgt actgattgac aatgaagggt acggtcaata
    12301 caaaggagaa acacaaatcg ccttgaagga tatgaaaaac gacggacgtg tcaatgttgt
    12361 aggaagaatc tccgatgacg aattattcct ccttgacttt ttgaaaccat ggtcaagctt
    12421 taaattaatt gaaaataaaa aatagataat tagttattgc agaaataatc cgctagaaat
    12481 agccagttat ttctgctttt ttattttgtt tttttatag
//
LOCUS       DAXLPY010000067        12456 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.067, whole genome shotgun sequence.
ACCESSION   DAXLPY010000067 DAXLPY010000000
VERSION     DAXLPY010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.067"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..153
                     /locus_tag="ACF3UF_002144"
     CDS             <1..153
                     /locus_tag="ACF3UF_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFD3672229.1"
                     /translation="SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTL
                     RYSLGY"
     gene            complement(207..485)
                     /locus_tag="ACF3UF_002145"
     CDS             complement(207..485)
                     /locus_tag="ACF3UF_002145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672230.1"
                     /translation="MENKVGYVRYNFFSSTPIMKDFASFNEALAVELSHDRERIHYEK
                     HVIINDLWNTEKTDLLALPDTDYPVFKEIEVKANKYNEIKQNKITNLS"
     gene            complement(600..1208)
                     /locus_tag="ACF3UF_002146"
     CDS             complement(600..1208)
                     /locus_tag="ACF3UF_002146"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672231.1"
                     /translation="MTDINTIRNLRNNHDKSINHIAKELDVNWRTAKKYADDDLLPQP
                     KARKKTGMMYTEKWGGIVSLWLSEDAKLPNKKRRTAEAMTTALKADGFPGSYRTVCVF
                     IQDWKATHYLETLEDQGFERLEHPPAEAQLDFGTMEVCHDGAFKDVKVLVMTFPFSNA
                     GFAVVLPAENQECLLEGMKELFSQSGGVPRKIRIDNMSTAVT"
     gene            complement(1612..2436)
                     /locus_tag="ACF3UF_002147"
     CDS             complement(1612..2436)
                     /locus_tag="ACF3UF_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3672232.1"
                     /translation="MEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAGANKKLV
                     YNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLKILTTFL
                     YVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKFVYDDFS
                     DELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGIPYINNL
                     GLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQHLEIS"
     gene            2779..3195
                     /locus_tag="ACF3UF_002148"
     CDS             2779..3195
                     /locus_tag="ACF3UF_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3672233.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3192..3662
                     /locus_tag="ACF3UF_002149"
     CDS             3192..3662
                     /locus_tag="ACF3UF_002149"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3672234.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3676..4449
                     /locus_tag="ACF3UF_002150"
     CDS             3676..4449
                     /locus_tag="ACF3UF_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3672235.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4463..5275
                     /locus_tag="ACF3UF_002151"
     CDS             4463..5275
                     /locus_tag="ACF3UF_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3672236.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5329..6294
                     /locus_tag="ACF3UF_002152"
     CDS             5329..6294
                     /locus_tag="ACF3UF_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3672237.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6431..9154
                     /locus_tag="ACF3UF_002153"
     CDS             6431..9154
                     /locus_tag="ACF3UF_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3672238.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9167..9799
                     /locus_tag="ACF3UF_002154"
     CDS             9167..9799
                     /locus_tag="ACF3UF_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3672239.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            10007..10231
                     /locus_tag="ACF3UF_002155"
     CDS             10007..10231
                     /locus_tag="ACF3UF_002155"
                     /inference="COORDINATES: protein motif:HMM:NF015692.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HFD3672240.1"
                     /translation="MQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEVI
                     PENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10333..10566
                     /gene="relB"
                     /locus_tag="ACF3UF_002156"
     CDS             10333..10566
                     /gene="relB"
                     /locus_tag="ACF3UF_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFD3672241.1"
                     /translation="MSQSTITFRIPDDEKELVLEYAKAHNSSLTELYRNAVLDKIEDE
                     IDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10556..10825
                     /locus_tag="ACF3UF_002157"
     CDS             10556..10825
                     /locus_tag="ACF3UF_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD3672242.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            complement(11004..12305)
                     /locus_tag="ACF3UF_002158"
     CDS             complement(11004..12305)
                     /locus_tag="ACF3UF_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3672243.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         4065 a         2016 c         2444 g         3931 t
ORIGIN      
        1 tccttagaaa aattaggttg tcaaaatttc aactcacgtt ctgttaaagg gctagagagt
       61 agatttgaaa gcatattact ggcttacagt gttctattaa gtcgagcaca acgacgtttt
      121 gaaggaactt tgagatattc tttaggatat taaaattaac tagcaccacg ggtaaaataa
      181 atagtttttc tatcaagtat attgaactac gataaatttg ttattttgtt ttgtttaatt
      241 tcgttgtact tattggcttt gacttcgatt tctttaaata ctgggtaatc ggtgtccggc
      301 aaagctagca aatctgtttt ttctgtgttc catagatcat tgataatgac atgtttttcg
      361 taatggattc gctctcgatc gtgtgacagc tccaccgcta atgcctcgtt gaaactggcg
      421 aaatccttca taatcggtgt agatgaaaag aagttgtacc gtacatagcc gactttgttt
      481 tccatactac ctttctcgtt tccgctacgt ggattgcaca cctgtgtctc aaaaccatag
      541 tgcatagaaa atcggaggaa accgtcagtc agcaccgctt gttcagtctt tgtttttgtc
      601 taagtaacgg ccgttgacat attatcaatc cgtattttcc gaggaacgcc acctgattgg
      661 ctgaagagtt ctttcatgcc ttccaacaaa cattcttgat tctcggcggg gagtacaacg
      721 gcgaatcctg cattactaaa agggaaagtc atcactaata ccttcacatc tttaaacgct
      781 ccatcgtgac aaacttccat cgtaccaaaa tcaagttgcg cttctgctgg cgggtgttca
      841 agacgctcaa agccttggtc ttccagtgtt tccaagtagt gtgtcgcttt ccaatcttga
      901 atgaatacac agactgttcg gtaggatcct ggaaagccat cggcttttaa agcagtagtc
      961 attgcttcag cagtcctacg ctttttattt ggcagcttag catcttctga aagccatagg
     1021 gaaacgatgc ctccccactt ttctgtatac atcataccag tctttttgcg tgctttaggt
     1081 tgcggcagca aatcatcatc tgcatatttt ttagccgtgc gccaatttac atctagctcc
     1141 tttgcaatat gattaatgga tttatcatga ttatttcgta aatttctgat agtattaata
     1201 tcggtcattg tgagcatacc tttcttacct ccagttacag tgtcgagact ataactttag
     1261 aggagtttca ggttgcccgc aatggctttt tatcttaact taatcgattt gcggagttgt
     1321 gtagtttttc gttgcacttg tatgtacttt tattctgcca taaacagctt aatgaatgtc
     1381 cacttgaaaa agtgaataaa cgaaatagat gactcgattt aataaggaag taaacccaca
     1441 cagaaatata ggtgattttc cttgaatgac caagatattg aaagttagtg aaaaaacaca
     1501 aaaaggtagc cctattcaca gaaggtctgc cttttgtgtt atcgccagca aacattagag
     1561 ggggtatttc atatagcttt tgtcctctcg acagtcctat cagtttctct tttaacttat
     1621 ctctaagtgc tgtccagttt taatagcttc tagcttgttt cctaactgtg tttttaatat
     1681 gttgaaggct tttgaacctg tgcagtggca agtaaggatt ttttctactc gtgagtcatt
     1741 caatttattt ccaattttca ttacctcttg ctcaggtaga cctaaattat ttatataagg
     1801 tatgccaatc atatggaagc caccaattag gtattttatg ggtttagtcg gaaatgtttc
     1861 aagagcaatt tccatcatat cgataatgcc atgatgacta cagccagtaa agacaatcag
     1921 accgtcttct tgctcaatta cgaccaataa ttcatctgaa aaatcatcat aaacaaattt
     1981 atcatccatc tttttgtata aattcttggt ggtcgagttt gctttgccta gggggatgat
     2041 atggaagctc ggagcaagtt ctgttttcgt ttttattgta tgtaaattct catgcatttt
     2101 aaggatttca tttttaggaa taccaacata cagaaacgtg gttaaaatct ttaaataatg
     2161 gggtaaagtt acaccttcag ctgtataaat aggggcgttt cctgatttta aatatcttaa
     2221 cccgccggtg tggtcagaat gaccgtgtga aataatcact gcctccagat cattcaaagt
     2281 ttcccccatt ttagtcgcat tatagactaa ttttttatta gcgccagcat cgaagagata
     2341 tttcttccct gagtagttaa ttaagagaga taacccatgt ccacttttaa agttcaaatt
     2401 tattcttgag ttttcaaata aaaccttgat ttccactata acatctcctt tcacatgaac
     2461 gcgtattcat atattgtagc acattaagtt ctattttttg ttgtaattac cgaaaaaaat
     2521 attaatggac gctttttacg ctttatttcg tatgtggaag aaaatttctt aggatgtggc
     2581 gggggattgg ggcaaagcta aattccaatt acagtgatca tttaattaga cacctttaaa
     2641 tacccacact ttcatcaaca ctataattta gggaaagaaa agtgttggca tgatatagaa
     2701 aaacctttaa ttaacagcgt ttcctaaaat tggcacgcat cttgcttata gaaaagcgta
     2761 aggataggag gaatgaaaat ggcaactata attcttgcca gccatgggga atttgctcaa
     2821 ggattaaagc aaacagcgac aatgattatt ggagatagtg taccaattca tgccttgtca
     2881 gcatttagag atgaagatga atctattttg gtacaaataa aaaaactttt agccacaata
     2941 gatatagaag aaacctacat tttaactgat attctaggtg gtagtgtgaa taatgatatg
     3001 ctcactatta ttaaagagta tgagggattg caattaatta ctggaatgaa cttaccttta
     3061 gttatttcta ttgcaaccta taatggaaaa attggggaaa gtgagctaga aaagcttatt
     3121 aaagagagtc aacaatcagt gattgattgt agaaaattat tagtagaaca acttactgga
     3181 ggagatgacc tatgattaag ttagtacgta ttgaccatcg tttgttgcac ggacaggtag
     3241 tattttcttg gagtaaatca ttaaatatca atcgtattat tattgccaat aaagaggcag
     3301 cgaatgatga attcaaaaaa atgtctttga atttatctaa accgactggc attaaattaa
     3361 caattttttc agttgaacag ttactagaaa aaatgcctaa aatcgaaaca cttaacgaaa
     3421 atatcatgct tatttttggt aatacaaaag aaattcgtca attttgtgaa gcctatccta
     3481 aagtacaaga aatcaactat ggagggataa tcaaaaaaga aggttccaag caatttagta
     3541 atgccatttt cttgaatgaa tctgagcaag aagatgccaa aaaattaaaa gctcttggca
     3601 ttaaacaatt tattcaacag gtaccaactt ctaaaaaaga agatttgaat acaatgttat
     3661 aaaggaggaa tgaaaatgct cgttcagtca attggtttag ggttaatcgg tgttttttgt
     3721 attttagact caaggctttt aggaagaatg aattttgaac gaccgttgat tgtcagtacg
     3781 cttgttggtt tggtacttgg agacatggaa aaaggattaa ttgttggagc ctctttggaa
     3841 ttgatgtcct taggattagt aaatatcgga gctgcttcac cacctgatat gaatatggca
     3901 tcaattattg ctacagcctt tgccatttta tcaaatgcga atgcagaagc agcattaacg
     3961 attgccattc caatttcagt gttaggtcaa atactaggta tcttaatgcg gacgattttg
     4021 tcaaatttga ctcacgttgc ggatcgcttt atcgaacaag gaaaatttag ccaagcaagg
     4081 agaattcata tactttatgg ctcgggatta tatgctctca tgtattttat tcctattttt
     4141 ctagcaattt attttggaac gaatcttgtt tctcagattg ttgatgcgat tcctgagtgg
     4201 ctaacaaatg gcttaacggt tgcaagtaaa attttaccag catatgggtt tgcgttgtta
     4261 ttacaaacga tgttaacgaa aaaaatggtg ccatttttat tacttggatt tttaattact
     4321 gcttattctg gattgggaat cattggtatt gcagccttcg catgtattgt tgcgtttgtc
     4381 atggttcaag ttcaaggtaa aaactcaaat ggtaaccaaa atgagccaga tccattagat
     4441 gacttataag gaggtagatt aagtgaaaga gaaagatcaa aatgcatgga aatatcggca
     4501 gttcttatgg cgttcatggg caattcaagc ctcatggaac tatgaacgac aaatgaacat
     4561 gggttttatg tacggaattg caccaattct agataacatt tacaagaatc cagaagatga
     4621 agcaatgaag aaagaagctt acgagcggca tatgatgtac tacaactgta cccctcaaac
     4681 aagtgcattt gtgttagggt taactgcttc tatggaggag caatactacg aagaccaaga
     4741 aaactttaat ccggaatcaa tcagtgcagt gaagacttct ctgatgggac cgctatctgg
     4801 tgttggtgat tctttctttc aaggaacgat tcgggtatta gcctttggac taggaattaa
     4861 tttagcccaa caaggtagta ttttaggtcc aattctagca atgttaattt cctttgtacc
     4921 ttccttttta gttacttact atggtgggaa aattggctat aacatgggga ataaatactt
     4981 gtctaaactg tatcaagaag gtttgatgga taaagtaatg tatgtttgct ccattgtggg
     5041 gttgatggtc attggttcga tgattgccag catgatcggg attacaacac caattcaaat
     5101 gggtaaagct tttgtcttac aagatgtatt agatagtatt atgccacaat ttttaccatt
     5161 aggattaacc ttcttcatgt actggttatt gcagaaaaag gtcaaaacag gatggatgtt
     5221 ggcaatctgt ttagtcggag gaattatttt tagtttgtta ggtatcttac aataagggaa
     5281 taaccaataa atttggttga ataatataaa taaggaggaa ttcaattgat gaattcaaaa
     5341 gaaattgtta aagaaatcgt agcgaaaaaa gaggtaaaat caatcgtatt tgttggctgt
     5401 ggcgcttcaa aagcggacct ttatcctgca aagtattttc tagaccaaaa tgcgaagcag
     5461 ttacggatta gtcattacac agccagcgaa tttaactatg caacaccagc atctgtagat
     5521 gagtcaactg tcgttatttc agcttcttta ggaggtacga ctccagaaac agttgaagct
     5581 aacgcagtag ctaaagaaaa aggtgctaca gttattagtc taacacgaag cattgactca
     5641 ccgttaacaa aagatgcaga ttatgtaatt tatcatcgat ttgcagagaa ctatgctgct
     5701 aaattagaaa aaacaggcta ctgtttagaa ttggcagtag aacttttaca tcaagtagaa
     5761 ggttatgacc attatgaagc aatgcaagaa ggatttgcta ctatctatga tcttgcccaa
     5821 aaaagtgcag aatcagctcg taaagatgcg aagaaatttg ctgaacgctt taaagatgaa
     5881 aaagttattt atgtaatgag tagtggtgct acacatgaag tagcatactc aacatcaatt
     5941 tgcttgatga tggaaatgca atggattaat tctggtacct tccattcagg agaatttttc
     6001 cacggaccat tcgaaattgt ggataaagac gtaccgttta tattattaat gaatgatgga
     6061 aaaactagaa atatagatgc tcgagcatta actttccttg aacgctttga tacgaaaaca
     6121 gaagttgtag atgccttgga ttatggcttg tcttcacata ttgctaaaga agtcttagac
     6181 tactttaacc cattcgtgat tactgcagta tttagagttt atgcagaaga attgtcagaa
     6241 gcaagagaac atccattaac taagagacgt tatatgtgga aactaactta ttaaaaaata
     6301 gatcaaacta aataaggtgg cttgagaaat taagccacct tgttttcttc aatgtgattt
     6361 tatacatatg gtaaaataac tagtacatat ggtaaaataa ctagtacata ttgtgaaagc
     6421 aggtggcaag atgcagcgat taaatgacta tctttatcaa ctaacattgc ttttgaaatc
     6481 tacgccttca gataattatt cagctcgcag tatttcgcaa gctctacagt tgaatagaag
     6541 tacaatcagt agctacttaa atgaaggtgt tcgtgaaggg cttttcataa aagtaaaaag
     6601 ttacccggtt ttatttttac atagaacagc tcttgaagaa ctacatatca cactgaataa
     6661 ctccgaaata gaatcaattg aaagcttgtt aacaatttct caaaaacccg cattagatca
     6721 agtaattggc tctaaaggaa gtttgaaaga agcaattgat caaattaaaa cggcagtctt
     6781 atatcctgga aaagggttgc ctttattatt gatcggcgct agtggatcag ggaaaacctt
     6841 tctagcgaat aaaatatatg aatatgcagt agaagaaaag gtcattcaca catcggcacc
     6901 tttcatagat tataattgtg cacaatatgt gagcaatcca gagttactat cctctgcttt
     6961 atttggctac acgaaaggag catttaccgg agcaagccag gagcatactg gtttgctaga
     7021 aaaagccgat ggaggagtat tgtttttaga tgaagtgcat cgcttatctg aagaagggca
     7081 agagaaatta tttacattta tggatacggg tgaattctct cctatggggg ataatagtat
     7141 tcggaaaaaa gccgatgttc gattagtctt tgcaacaaca gaaaatatat atacgacttt
     7201 cttaccaact tttcttagga gattgccagt tattgttaat ctacctagat ttcaacaacg
     7261 tccgtcgttt gaacgtctgt cattgattga tgaatttttt gtttctgaga gccaaatttt
     7321 agctaaggaa ctatctgttt ctgatgcatt gattcatttc ttaatgaata gtgattttga
     7381 aggtaacgtg gggaatatta aaaatattat caagtatgct tgcggaaacg catatatcca
     7441 ccagaagagt cagcaaacaa ttcaagttaa attattggat atgcctttag agtacagtta
     7501 taaattcaag gagcaactaa ataaacccag aaagaaaaga gcagatcgaa tctactatcc
     7561 agaagaaaca cgacaagtgc aactagaaag aaacaatcag ctttttgttc aattttttga
     7621 ccaattactt actggattct ctgaagtgat tgaaaataac aaggatatta aactattttt
     7681 agaagaaatg gttaccaagg taacacaagt aatggatacg cttatttttc aagaggatta
     7741 cgaaaaagag cagtctttat acgccattct aaactatcat attcgtcaaa gtattgattt
     7801 tatgcgagaa agctacgggt ttgaacaaga tggtaaccgg gtagtcgctt tggccaacta
     7861 tctatatgtc aaggataatc aagtgatttt tgaaaatagt cttcaagaaa agaaaaccaa
     7921 agatcagctt aacgaatttt ttgctaatgt tcttgaaacc ccttattggt atgcaaaaaa
     7981 aatcttaagc cttttatctg agtgtttaga tcaacctgtg tatgaagagg acattttctt
     8041 tattacgcta tatttttata gtttgaatgt cacgaatgtt aaaacaggta ttaagagtat
     8101 tgtgctagct catggttatt ctacagctag tagtatggcg aatgttgcca accgtatgct
     8161 gaataagaac gtttttcaag cttatgatat gcctttagat attacattag agaaaattga
     8221 agcaaaattg attcaattcc ttggagatta tcgaacagat tcaggcttga ttttattggt
     8281 agatatgggt tcactaaacc aactaggcgg tttattagtg aatcatctaa atggaccact
     8341 gttaatcatt gatcatatca atacaccgtt attattggaa gtcggccaac aagtattaaa
     8401 caataaaagt atcaccgaaa taggagcaga aattgaaaca agtcttactt tcaaaaagca
     8461 gttactactt cccaagaaaa agaaaaagaa agccatcatt acttgttgtt atacagggat
     8521 tggtagtgcg acccagattc aggagatttt aacgaaatgc ttgaaagatg cagttagaga
     8581 attagtaatt attccgtatg attacaaaaa gctgttagaa aacaagaatt ttgagactcc
     8641 ttttcaatta tacgatgtca tcatgattgt aggtacagaa gatcccaaaa ttaatcagat
     8701 tccatatatt ggattagatc gcctgattaa tgggggaagc attggcgaat ttgttcatta
     8761 cttggaaaaa gagctgacta ttgaagtgaa cgatttacaa aaagaattaa ttttcaattt
     8821 ttcaattagt aaaattgtcg aaaatttaac cattttggat ccagataagg tgctatcttt
     8881 tgtacaaaaa gcaattaaag aattatcgaa gttattaaat tttgattttt ctaataatca
     8941 gctgtttttg ttgtaccttc actgtagttg tatgattgaa cgaattgtac gtaaagaaag
     9001 tgtggatgag caagaggaca ttgaagaata tatgcaagca aatggagaaa taatggataa
     9061 aattcatagc gctttttttg agattgaaag ggaatacaca attgaaatac cagatttaga
     9121 gttgcgatta ttgagcgata ttgttcaagg ataggagtga attcgaatga caatgggagt
     9181 aatttttgat atggatgggg tactcataga tagcgagaca ttttattttg agagaagaat
     9241 gaacttcttt caagaactgg agatagatcc aggatcaaac cagattgatg attatgtggg
     9301 gaaaacagaa gctgcaatat gggaaacatt agttcctgag gacaaatcat taagagagga
     9361 actttatccg aaatatgtag attatcgaaa aacgcatcca attgatttcg ctaaagcttt
     9421 acgaaaagaa gtgaaaccgt tacttgactt cctcaagaag cgggatatac cattggcact
     9481 ggcatcttct tctccagctg tcgagataga gagtatgctc attcaatgtg aacttactga
     9541 atatttttcc tttgttataa gtggtgagtc attaaaacaa agcaaaccac atcccgaaat
     9601 atatttaaaa gcgaaacagc aattagactg tgacttcttt attgcagtag aggattcaac
     9661 gattggtatt aaatcagcaa aggcagcaaa tatctatacg gcggcactaa aacaaccaat
     9721 gcaaatcgat cagagtgaag cagacataca aattgaaagt ctacaagaac tggaacaaat
     9781 tgttttagaa aaaggttagt gaattaatgg aaataaggct atatatctgt gctagctatt
     9841 ttgactaacc aaaaaaactt gctataattc aggtgtagta aaaggtgctg gtaacacctt
     9901 ttacgaaaat gcttcggcag tgataatggg attggctttt taagtttttt attttgttcg
     9961 caatccctaa ggtcatgtga atgatcctag ggattgctag aatattttgc aacagaacca
    10021 aaatacgaat agttatcaag cagccatatt gactgcggtc aatttaggag gggatactga
    10081 tactactgct gccgtaactg gtgctcttgc gggtattctt tacgggggtg aagtgatccc
    10141 tgaaaattgg agaaaatcgc ttcaaaatga ccagcttctt aaaacgatca gtcagagatt
    10201 ttgcgatacc gtgctatctc aaagaatttg aataatggat atgatgcaaa tcttgtttgt
    10261 actaacgttg tattgacaaa aaggatttta tttagtacaa tgttagtaca aatgatgaac
    10321 ggaggtagaa tcatgtctca atcaaccatt acatttagga ttcccgacga tgaaaaagaa
    10381 ctggtattag aatatgcaaa agcacacaat tcttcattga ccgaacttta tcgaaatgct
    10441 gtactggata aaatcgaaga tgaaatcgat ctacggactt tacggagtgc aattgaagtt
    10501 tccaaagaga aaaaagagag tggtatttct caagaggaaa tggagaaact gctaaatgaa
    10561 ttataaagtc atctacatgc cgcaagccca gaagcaatta aaaaaaatgg acagaaacca
    10621 agctaaaata attgtcgcct ggatcagaaa gaatttagaa aacacgactg acccgcgtca
    10681 gcacggaaaa ggtttgactg gaaataagag tggggaatgg cgctatcgaa ttggaaacta
    10741 tcgaatattg gctaatattt gtgattctga aattgaaatc cagatattct caattggaca
    10801 tagaagtaca atatataaaa gataaccgtt tttggaacga agtagagttt cgaaagtcaa
    10861 tgtataatct tttgaatttt gcataatacc acaggtagaa actacccgat actatcggtt
    10921 ggtttctgct tttttatggc tctttgtcaa ataggactga tagagtgaga taagaacatc
    10981 taaggtagaa ttccttttct actttagatg ttttttgatt cataggtaat cagattattt
    11041 agtaagaaaa ttctggtctt cattttccga aagcttcgaa agccataagc gactcgtttc
    11101 aatgctttga tgtgggtatg cagattttct attttggcat ttgaataagg caattcgagg
    11161 gctaaacgaa tgccggattc atagtttata aaagcttttt ttatagaatg cagttctttt
    11221 ggaacggaat tgggcatcgt tcttacaagt ttaaagaaag tgtccgcctc tttgtcgtga
    11281 aacgcttgaa gaatttcttg atagtaaaaa taggcgattc gtaattcgtc agagatcgaa
    11341 agcagacgat ccaccacttc actttcggtg agatacgccc aaccaaaatt gcgccatttg
    11401 gtccatttgt cataaacaag cttgtcctgt cgtttgatca gaagccgaga caacgccttt
    11461 aattgtcgat aatatttggc ttgtgttgga tcgtttcgat caaagctttt catgattcgt
    11521 acgcgaatat cctcaaattt acgaatgaga tgtttgacaa tgtgaaaacg atccacaacg
    11581 agttttgcct ttggaaaaca ttcctttatc agagaggcat aagaaacatt catgtccgtc
    11641 acgatgacct ttaccttcaa tcgtgcgcgt cgttcaaatt gcataaaata agaaacgaga
    11701 gcctttttct tccgtgaagg aagaatatcc agtaattttc cagtatcgcc atccatacaa
    11761 gaaaaggagt agggaccgac ttgatttttc agtgaacgaa attcatccat taataaacaa
    11821 cgcggtaacc aatttctttt tacttttgtc atggggatca gagaagcgag tgtccgagaa
    11881 acggtcgacc aagaaacgcc gcaatgctta gcaattgtcg tcattgcttg tttttcagtt
    11941 agctcttcta aaattttata gcgcacttgt ttagcgataa agcagtttct atcgacaatg
    12001 taggtattcg ccgtaaaata ggtgtggcag ccacgacagt ggtagcgttg tttcgctaaa
    12061 gcaagataag tcagttggtt cgcacattta ttaagttgaa tgagcgattt tttctttccg
    12121 ttcttaacga tcatgccttc atgattcatc tgtttacaca aaggacagcg acgaatttct
    12181 ttacttaacg tcgcagaaac aacaagactc ttgatattct taatgctctt cgattccaca
    12241 tttgtgatga aaatgttttt atctttgatt ccaagtagta gtttgatatg atgaagatca
    12301 ggcatacaga acgctccttt gattgtgttg tggtgattca attctaacgg agcttctgta
    12361 tgttttgttt tttcatgctc aaaagggacc gatagaatga ttttctatca gtcctagaaa
    12421 ttatagagcc ttttttattt ggtcttgaag aagaaa
//
LOCUS       DAXLPY010000068        12359 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.068, whole genome shotgun sequence.
ACCESSION   DAXLPY010000068 DAXLPY010000000
VERSION     DAXLPY010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.068"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(180..737)
                     /gene="frr"
                     /locus_tag="ACF3UF_002159"
     CDS             complement(180..737)
                     /gene="frr"
                     /locus_tag="ACF3UF_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFD3672244.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(740..1462)
                     /gene="pyrH"
                     /locus_tag="ACF3UF_002160"
     CDS             complement(740..1462)
                     /gene="pyrH"
                     /locus_tag="ACF3UF_002160"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFD3672245.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1598..2479)
                     /gene="tsf"
                     /locus_tag="ACF3UF_002161"
     CDS             complement(1598..2479)
                     /gene="tsf"
                     /locus_tag="ACF3UF_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFD3672246.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2578..3360)
                     /gene="rpsB"
                     /locus_tag="ACF3UF_002162"
     CDS             complement(2578..3360)
                     /gene="rpsB"
                     /locus_tag="ACF3UF_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFD3672247.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3719..4198
                     /locus_tag="ACF3UF_002163"
     CDS             3719..4198
                     /locus_tag="ACF3UF_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD3672248.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4415..5506
                     /gene="phnW"
                     /locus_tag="ACF3UF_002164"
     CDS             4415..5506
                     /gene="phnW"
                     /locus_tag="ACF3UF_002164"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFD3672249.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKELLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5499..5627
                     /locus_tag="ACF3UF_002165"
     CDS             5499..5627
                     /locus_tag="ACF3UF_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFD3672250.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5631..6176
                     /locus_tag="ACF3UF_002166"
     CDS             5631..6176
                     /locus_tag="ACF3UF_002166"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HFD3672251.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6630..8321)
                     /gene="argS"
                     /locus_tag="ACF3UF_002167"
     CDS             complement(6630..8321)
                     /gene="argS"
                     /locus_tag="ACF3UF_002167"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFD3672252.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8741..9688)
                     /gene="arcC"
                     /locus_tag="ACF3UF_002168"
     CDS             complement(8741..9688)
                     /gene="arcC"
                     /locus_tag="ACF3UF_002168"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFD3672253.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9803..10822)
                     /gene="argF"
                     /locus_tag="ACF3UF_002169"
     CDS             complement(9803..10822)
                     /gene="argF"
                     /locus_tag="ACF3UF_002169"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFD3672254.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10913..12142)
                     /gene="arcA"
                     /locus_tag="ACF3UF_002170"
     CDS             complement(10913..12142)
                     /gene="arcA"
                     /locus_tag="ACF3UF_002170"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFD3672255.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3395 a         2548 c         2215 g         4201 t
ORIGIN      
        1 acttaaaaga ttcccactat cttaagtatt atagcaatat ctaactgttt ttcctatgaa
       61 atcattgttt ttttatttaa aaactgaata attttttctt tttttaattt ttaaataaaa
      121 gaaatataaa taaaaacaga ggaagcggaa tgatccgccc ctctgttttt atgattttat
      181 taaacttcca ataattcttt ttctttatca gcagcgatct tatctacttc tttgatgctg
      241 ttatctgtca atgtttgtac gtctttttct aatccgcgca aatcatcttc ggtaatatca
      301 ccattttttt gttgtttttt atattcatcg atcgcatcac gacggatgtt acgaatcgcg
      361 atttttgcat tttctgcttc ttttttaaca tctttagcta attcttttct gcgttcttct
      421 gtcagttgcg ggataactaa gcgaatgaca tttccatcat tggttggact gattccgata
      481 tcacttgcca taatagcttt ttcaacatct tgaagaatgc tcttgtcaaa aggtgtgatc
      541 attaaaacac gtgcttctgg aatttggatt gatgccattt ggttcaatgg tgttggcgca
      601 ccgtagtagt tcacagtaat acggtccaaa aggctagcgt tcgcacggcc tgcgcggatt
      661 tgcccaagtt cacgttgaag attttgtgct gcttttttca ttttttcttt tgcttctgtc
      721 ataattgcat ctgccatttt tatttccccc ttacagttgt tccgatattt tcgcctaaga
      781 ttgcacggcg aatatttccg tgttcattta aattgaagac aagcagtgga atatcattat
      841 ccatgcttag tgaacttgca gttgaatcca tgacttgtaa tcctttggca ataacttcca
      901 gatgagtcag ttcttcaaat tttactgcat ttgcatctac tttcggatca gcagaataaa
      961 caccgtctac attgttttta gccatcagga taacatctgc gccgatttct gccgcgcgta
     1021 atgctgctgt tgtgtctgtc gagaagtacg ggttgccggt accgcctgca aagataacga
     1081 tccgtccttt ttctaaatga cgttctgctt tacggcgaat atatggctct gcgatttgac
     1141 gcatttcaat cgaagtttgc acgcgtgtcg gtacacccac gttttccaac gtatcctgta
     1201 aagctaaggc attcataact gtagctaaca tacccatgta atcagcttga gcacgttcca
     1261 tgcccatttg tgctccgatt tgtccgcgcc agatatttcc gccgcccaca acgattgcca
     1321 tttcaacgcc cagctcgtga acttctttga tttcttggat gatttctttg attactggtg
     1381 gtttgattcc aaatcctgcg tccccagcta aagcttctcc actcaatttt aagactacac
     1441 gctgatattt cggtgtgacc atgttcattc ctccaatatt ttctattgcc attttaccat
     1501 acttagatga tttcgacact ctaagactgg tttttcttgt tttgcttaaa aaaagggagc
     1561 gcacaaaccg tgcgttcccg tctgttattc aacagaatta ttttttcact tggctcataa
     1621 cttcttctac aaagttatct tcgcgttttt cgataccttc gccaacttcg aaacgtacga
     1681 atgttttaac agttgcgcct tttgatgcaa cgtatttttc aacagtcata tcaggatctt
     1741 taacgaatgg ttggtccacc aaagcgattt ctgctttgaa tttcttcaag cgtccttcta
     1801 ccattttttc aacgatattc gctggtttgc cttcgttcaa tgcttgttct gtaagaacag
     1861 ttttttcatg ttctaattca gcttctggaa tttgtgattc gtttacataa cgaggattga
     1921 tagctgctac gtgcatagct acgtctcttg caactgtttc gtcagttgtt ccatctagaa
     1981 cagtcaatac ggcaatacgt ccgcccatat gcaagtatcc accaaatgca gcattgtcgt
     2041 ctttttctac aacttcaaag cgacggaagc tgattttttc tccgataact tgagttgctt
     2101 cgatcaagtc agattcaatt gtacctttat ctgttttgat tttcattgca gcttccatgt
     2161 ctgctggttt gttttcagca acaagttctg caatttcttt tactaaatct tggaacattt
     2221 cgtttttaga aacaaagtct gtttctgagt ttacttcaac gattgctgca gtgttacctt
     2281 tcacagcaac tgaagccaat ccttcagctg caatgcggtc atttttcttc gcagcctttg
     2341 ccattccttt ttcacgtaaa agatcaactg ctttttccat gtcgccttct acttcaacta
     2401 atgctttttt cgcatccatc attcctacgc cagtcatttc gcgtagttct tttaccattt
     2461 tagctgtaac gtctgccatg tttaactcct cctgtgtgtt tttcttttta aaaaaagctg
     2521 cttcaaagga gagtgaggct tgtcgcccag cctttgaaac agctccatca ttcaaaatta
     2581 ttctgctgaa gaattgtcgc cttcaacaac atctacgatt tcttcgattg atgttgctgt
     2641 gttttcttct gtgaaatctt cttcaactac ttgatcttca ccttggtttc cttcgatgaa
     2701 agcatcagcc atttttgaag taatcaattt aacggcacga attgcatcgt cgtttgaagg
     2761 gattactacg tcgatttcat ctggatcgca gtttgtatca accatagcta cgattgggat
     2821 atttaatttg tgtgcttctt gaacagcaat acgttcttta cgtgggtcaa cgatgtacat
     2881 tacatctggg attcttggca tatcagcgat accgcctaag aatttttcaa gacgttcacg
     2941 ttctttgttc aaaccagcaa cttctttttt aggtagaact tcaaaagttc catcttcttc
     3001 cattgcattg atttgtttca aacggctgat acgtttttgg atagtatccc agtttgtcaa
     3061 tgttccgcct aaccaacgat ggttaacgaa gtattgtcct gcacgagttg cttcttcttt
     3121 gattgcttct tgtgcttgtt tttttgtacc tacgaataat gctacgccgc cttcttcagc
     3181 aacgctcttc atgtaatcat aagctgcatc tactaattta actgtttttt gcaagtcaat
     3241 gatgtagatt ccgtttcttt ctgtgaagat atatttcttc atttttggat tccagcgacg
     3301 agtttggtga ccaaagtgta cgccggcttc tagtaattgt ttcatagaaa ttactgccat
     3361 gtttgtttcc tccgatttgg ttttattttt cctcttctta tcttctacct tgccggcaaa
     3421 ctttttcaag cacctaccga caatccaata agaatgtgga tttgctgatg cataaagcac
     3481 cctcagctat tatacagaca aaagatccgt atcgcaagag caaatatact tttctgctca
     3541 acattcaata gtttacctga aagataaaaa gaattcaaga aaaacagtag atttctcttt
     3601 gtttctttat tatccttttt ccataaaata attttaggta taaaagacga atattattgg
     3661 gcaatccttc ttttttttgt tatgatacat gtgaaatctt tcgtaaagga gaaagaaaat
     3721 gcgcaaagct caaagacatt tgctgattaa acaagtcatt gaagaattcc cgatccgtac
     3781 gcaagaagaa ctattaaaca aacttgggca ttatggcgtt accgccacgc aggcaacgat
     3841 ttctcgagat atccgtgatc taaaaatcgt gaaggcacct gatgaaaatg gcgtttcccg
     3901 cttcgtattg tttcgcgaaa aaggaactcc tgagactagg actgaggaag aggatcggct
     3961 ggttcaaatg attgaagaca ttgtattgaa agtcgaacga gtccactttt tgacgatcgt
     4021 caataccttg ccagacaatg ctcatttatt tgcatctgtt ttagatgaga tcaaacctcc
     4081 ctctattgtc agtacaattg ctggattcga tacgatcatg gtcatctcgg aaaatgagga
     4141 ggacgcaaaa cgagtagaag aatttcttca ccatccaact gaagtatcac ttttttaatc
     4201 agagcacgta ttcctaatat ggaatgcgtg tttttttatt ttcaatattt tccttattga
     4261 ataaaccttt acactcttta caaaaataca tcatttttta ttcaaatttt tcaacacctt
     4321 gattgaatca caataatcat catttatatt ggatgttaac aagagcagct tcttgctctt
     4381 tgtgtatttc aaaaaagaaa tgaaaggaaa tcatatgtat aaattattaa cttctggacc
     4441 attgacgact tctgaaacag tgaaaaatgc tatgctgatc gatcattgta cttgggatca
     4501 agaatacaaa gaaattacac aatggataag aaaagaatta ttggatcttg ctcaagtatc
     4561 ggaaggaata tacacaacgg tcttaatgca aggtagcagc tccttcgggg tagaatcggt
     4621 attaagttct gtgatcaggc cagaagatac tgtactgatt tgttcaaacg gcgcatatag
     4681 acaacgaatg atcaacatgt gcgaatgtct gaaactgaac tataccgttt atgaggtatc
     4741 ggaacatcaa atcctccaag ctcatgtgat tacacagctg attgaagaga atccgtctat
     4801 ctccgcacta gcaatggtcc atagcgagac tacttccggt attttgaata atttggaaga
     4861 gattgctgct gtcacgcaag aaagagatct tttgtttata gtggacgcga tgtcaagctt
     4921 tggtgggata ccgatttgtg tagccgaact agggattgat tttttgattt ccagctcaaa
     4981 caaatgtatt caaggtgttc caggcttttc ttttgtactt gctaataaag cggaactgga
     5041 aaaacgaaaa aatgttagcc gaagtttgtc acttgatcta tatgaccagt accgcgtgat
     5101 ggaaaacgag aatggcaaat ggcgtttcac ttcccctacc catacggttt tggcttttca
     5161 acaagcgctg aaggaactag aggcagaagg aggaatcgaa actcgatatt cacgttatct
     5221 cgccaataat catgtgctac gacaaaaaat gacagagatg gggttccagc ctttcattca
     5281 agaatatcag gggccattca tcacctcttt tctttaccct aaggactggc gatttgattt
     5341 taatcatttt tatcagtatt taaagcaaaa tggatttgtg atctatcccg ggaaaatcag
     5401 cgatcatgaa tgttttcgta tcggaaatat tggcgagatc tatccggaag atattttgga
     5461 actgacagca attatcaaag actataagga gaacgttaat gattaaaact gtaatttttg
     5521 attgggcagg aacaactgtg gactttggct gtatggctcc tgtccacgct tttagaaatg
     5581 cttttctaga aaaaggaatc caactgactg acaaagaaat ccgctaaccg atgggaaaat
     5641 taaaatggga tcatatccaa cagcttcttt ccctcccttc tgtcaaaaaa caatggatag
     5701 ctatttatgg acaactacct caggaaaaag aggtggagga attgtatcaa caatttgaac
     5761 attatctgtt taaagatttg gtcaagcatt ctaccttgaa acccgacaca ttggaaacga
     5821 tcgaacggtt gagaaacgct gggatcaata ttggttccac gaatggattt aatgctccta
     5881 tgatgacaat cgtagcagaa accgcaaaaa aagaaaggta ttcaccagac ttcatggcaa
     5941 cttttgaaga cgtcgaaggg tatggtcgac cgtttcctta tatgatccat aaaaacatgc
     6001 agtacttcaa aaacaagtcg gttgatgaag taatcaaagt cggagatacg gtctcagata
     6061 tccaggaagg gaaaaatgcc ggagtgttga cagtaggtgt aattgaaggt agttcgctaa
     6121 tggggatttc ttatgatgag taccaaaaat tagagatggg gaaaaagatc gtttaaaaca
     6181 gtctgttgct cttagattcc aacaagccgg cgctgatatt tgtgtaaaca atttaaaaga
     6241 gttaacagaa tacattttgt acgctgacat gaatccagaa tgacttttat acaaaataag
     6301 aggttgtgaa aaagctgtcc tgtatcaagt aataaaaaca gccaagcaaa aatagctcct
     6361 catatttttc gtttggttag gcttattacc gcagatgcaa gcttttgaac accgtttatt
     6421 cgaaaaaaaa aagggagctg tgacacgact tttgtcacag tccccttatt tgcaaacaaa
     6481 cagtgtttaa gagacaacct ctccactaaa cggtgttcat tcagctgact ctcggtattt
     6541 gctcaaaaaa cgataaaatt tgaaaagcta ttttctcttt tgtttctcta atactcggat
     6601 cagaacgctg atttcacatt ctctttttct tacatcttat ctggtgcatg aagtcctagc
     6661 aaacgaaggt cttctttcaa taatacagtc actgcataaa ctagagctaa gcgtgcttct
     6721 ttttgttcat catcagctaa aatcttcgta tgagcatagt atttgttgaa tgcttgtgct
     6781 aatttgattg catgtttcgc aatcactgac ggttcgtatt tttccccagc agacaagacc
     6841 gtttcagggt atttttgaac taatttaacc acttcccagc tggtatcgtc attcaatgca
     6901 tagtctgctg tttctgaagg gacaaatcct gctttttcca acaggctgac tgcacgagca
     6961 tgtgtatatt gcacataagg tccagtttct ccttcaaatc gaacaacttc ttccaggtta
     7021 aagtcaaatg tattcagtcg atcgtttttc aaatcgtgga aaatgactgc cccaacccca
     7081 acttgtttag ctacagcatc tttgttttcc aaatcagggt ttttctcgct gatttgttct
     7141 ttagcagatt ggattgcttc atttaatact tcttctaata agacgatctt tcctttacga
     7201 gttgataatt ttttaccacc ttgcgtgatc aaaccaaatg gaatatggtg catgtcgtca
     7261 gaccagtcaa agcccatttc cttcaagaca gctttcaact gtttaaaatg atagctttgt
     7321 tcattcccta ctacatatag agattgtttg aagtcgtaag tacgtttacg gtacaatgca
     7381 gcagctaagt cacgtgtaat gtatagtgtc gcaccgtctg acttcttaat caacgctgga
     7441 ttcaggtcat aagcagatag gtcaacgatc tctgcacctt tatcctcgtt cagcaaatgt
     7501 ttttcttcta aaagtttgac gatttcatcc atcttgtcat tgtagaaagc ttcaccgttc
     7561 aacgaatcga aacgtacttc cagcagatca tagattttat tgaattcttt catcgattca
     7621 tcacggaacc attgccataa ttgaatagcc tctttatcgc cttcttccag acgtttgaac
     7681 caagcacgag cttcttcatt taattctggt tctgtttcag ctacttcatg gaattggacg
     7741 tataaacgaa gcaattcatt gattggttct gctttaacag cttcttctgt accccatttt
     7801 ttgtaagcga cgatcagttt tccaaactgt gttccccagt cacctaaatg gttgatgcgg
     7861 attggctgat aaccgatttt ttccataatg aaaccgatcg aattaccgat aactgtcgaa
     7921 cgcaaatgtc ccattgagat tggtttggca atattaggag aagacatgtc gattggtact
     7981 gttccttgat tcccgatgtt gctatcccca taatgttctt tttctttcac tactgtttgc
     8041 aaaacttttt tgctgataag ttctttattc atgaaaaagt tcaagtaagg tccgacaact
     8101 tcgatttttt caaagttggc agaatcgatt ttttctgcta aatctgcagc gatttgctgt
     8161 ggcgcttttc ggtaaacttt tgctaatgaa aaggctggaa atgcaacatc tccgtgttca
     8221 gctgattttg gattttctag taattgctcg acttgttcca gtgttaaatc atctttgaca
     8281 gcgtcataga cagcttttgc gacaagatct ttattattca tctttattcc tcctaaagtg
     8341 ttcccttgat tgttaaacaa aaaaaatctc tagcgacggc atacttagta tgccatcact
     8401 agagacgaga tttcccgcgg taccactcca attgtcctaa aaaaggacca gctccatctg
     8461 atatcggtag acgaccgtct gtttaaaaca gaattctcca agtgcgcttc gttgtatctt
     8521 cttcattcgg cttccaccac ttccgaattc gctagccaag aatgatacaa gtactctctt
     8581 gttcaacaaa tcttagtctt attaaacttt cttgaattat atcagaaaaa aaaacgaaag
     8641 gctagtcgtt tcataaaaaa acaatccaga tggcctaaag gagaagaaat accacctgga
     8701 tagctataaa tcatttcgta aatacgaaag acttaacaaa ttaatcagct acgataatcg
     8761 ttccttcttc agaagctaaa agattctcga tattttctaa agaagtgatg attgccttag
     8821 cgtttggttt tgcttcaaca aatgcaatag ctgcttctac tttcggaagc atgcttcctg
     8881 gagcgaattg cttttcatca atgtattgtt tcatttctga aacagtaaca gtttctaatt
     8941 tcttttgatc tggtttttgg taattgacat acacattgtc tactcctgtc aatacgatca
     9001 gcaaatccgc atcgatgatt tcggctaatt tttctgaagc aaaatcttta tcgattacgg
     9061 cttctcgtcc ttctaatcca gtagctgttt ctacaacagg aatcccaccg ccaccaacag
     9121 agactgtgat aactccttga tcgaccagcg tttcgatgac acgtgcttct ttaatcgaga
     9181 tgggtttagg ggaagcgact acttttctcc atccacgtcc agcatcttct ttgaatgtca
     9241 cagtggagtc agcattcatt tgttctttgg cttcttcttc cgtgtagaat ggaccgactg
     9301 gtttacttgg atttttgaat gaaggatcat tttcatccac aataacttga gtgactaaag
     9361 aaaccacatc tttatcgatc cctttttcct tcagtacttc gcccatggcg ttttgtaacc
     9421 agtaaccgat agatccttct gtcattgcaa cacatgtatc taaaggcatt gccggtgttt
     9481 tctcagaatc agcagcttgc tgctgaatca ataggttacc gacttgcgga ccatttccgt
     9541 gggagatgat caattcatct ccttgttcga taaatttcac taaatacttt gctgtttcca
     9601 ttaacgcttc ttgttgggct tttgcacttg catccgtaga caagatggca ttgcccccta
     9661 aagcgacaac tacttttcgt ttggccattt cattcgtcct ttcttcagtt ctaccgaatt
     9721 ttctagataa caaaacgagc cagcgttttg tgattttccc tcaatgctga ctcgtttttt
     9781 cgtgagatga atgtggttat gcttaaacgc gagggataaa caagttacct aatgttgctg
     9841 ccatgatcgc tttgattgag tgcatacgat tttctgcttg gtcaaattga cgagcatatt
     9901 tgctgcggaa gacttcatct gttacttcca tttcagtgat gccaaagcgt tctttcattt
     9961 gttcaccgta aacagtgttt gtatcatgga aagctggcaa gcagtgcaag aagatcaaac
    10021 gatctgtgtt gtgtgttttt tctaccattt ccatattgat ttggtaaggt ttcaacaatt
    10081 tgatacgttc ttcgaattta tcttcttcac ccattgatac ccatacatca gaataaagga
    10141 cgtctgctcc gtctacacct ttatcaacat cgtcggtaat catcaattgt gcaccggatt
    10201 tttcagcaaa gccttctgcc attttgacga tttcttcttc aggttgtaat tcttttggtg
    10261 caacgatacg catattcgct cctaaaattg cacctgtgac taataaagag ttagccatat
    10321 tgtttcgacc atctccgcag taagcaacag tgataccttc tactgttcca aagttttctt
    10381 ggatagttaa aaagtcagcg atcatttgtg ttggatgcca ttcatcagtc aagccattcc
    10441 aaactggaac accagagaat tctgctagtt cctctaccat tttttgactg aatccacgga
    10501 attcgattcc gtcaaacata cgtcctagta ctttagctgt atcttctgtg gattcttttt
    10561 tacctaattg gatatcattt gcacctagat attcaggatg tgcacctaga tcgatcgctg
    10621 cagtagtaaa tgcagaacga gtacgtgtag atgttttttc aaataaaagc gcaatatttt
    10681 ttccttctag atagtgatgt gggataccac gttttttcaa gtctttcaag tgttctgaaa
    10741 aatcgatcaa atattgtaat tcttcttttg taaagtcttt ttctgctaat aagcttcttc
    10801 cttggaatac tgattctttc atattaaaca ttctccttta gattgttttt atttaagatt
    10861 aaagaggaaa tcccgacggc agctgacagt aagactgccg tcaggaaaca aattacttca
    10921 agtcttcacg gacaagtggt tggctcatgc agcgtggacc accacgacct cgtgacaatt
    10981 cacttgaatt gatttctaac actttgatgc catagctacg aagcaattcg ttcgatacat
    11041 aatttcggtt ataagtgact acaacacctg gagcgattgc caatgtgttt gatccatcat
    11101 tccattgttc tcgaggtgca acgatctcat ctccattacc agttgggatc agtacaagat
    11161 catctaatcc aagagcagct ttcatcgttt cgtgtaagtt atctgaatga gtaatcttga
    11221 tatcatcacc atctggttcg attgtaaaga catccatctt accgtcttta ctttgaattg
    11281 ctggatggat agtgaattta tcgtgatcta ccattgtaaa tacggtatcc aaatgcatca
    11341 ttgcacggtt gttcggaatt ttgattgcca acactttttc aaatcctgaa ttttttgcga
    11401 ataggtggcg tgctaatttt tctaaagctt tcgcattagt tcgttgagaa atcccaacag
    11461 ctactacttt atcgcttaag atcaattcgt ctccgccttc gatatgatct ggattttcac
    11521 gatccaacca tacttcgatt cctttatttg caaatcttgg atgatgtttc aaaatatatt
    11581 ctgtaaacat cgattcacga cgacgtgctt caaaagtcat cttattgact gtcatcccat
    11641 ttcccattga tgcggaaggg tcgcgtgtaa agtacaagtt tggcattggg tccatgtaaa
    11701 atggatagtc atcgtctgct gacagatcat atagactgct agaacgtact tcgatatctt
    11761 ttgtacgaac cccagccatg attttatcta ccatttcttg cgtttccatt gatagaagga
    11821 actcatgaag accctctctt acagcattcg atgcaatatg agattcatcc aacattttat
    11881 tcaagaattg ttctttgaca ttgcctgcgt caatcgcttc tgccgctaat ttttccaagt
    11941 aaagagtctc gacgccttca ttttgcaatg tcttcgcaaa gttgtcatgt tcttcttgag
    12001 caatcggaag atatggaata tcatcgaaca acagacgatc cataatatct ggtgtcaaat
    12061 tttccacttc ttgtccaggc cgtttcagta aaactgtctt taatttccct atttcagaga
    12121 aaacgtgaat aggtttatcc atgttgtgtt gcctccttct ttttgattac atgtatagga
    12181 tatcctcctt ttgtaatcac tttcataatt ttgtctcatt caaaacgaga cattcctcac
    12241 attaatattc gataattaaa taattaaacg tttttctatt tttaagcgta atttattcat
    12301 tttttattct gtatacactt tcaaaaaaat atttattcat tgaaaaaatt tttttgaat
//
LOCUS       DAXLPY010000069        12252 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.069, whole genome shotgun sequence.
ACCESSION   DAXLPY010000069 DAXLPY010000000
VERSION     DAXLPY010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.069"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..435
                     /locus_tag="ACF3UF_002171"
     CDS             <1..435
                     /locus_tag="ACF3UF_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFD3672256.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="ACF3UF_002172"
     tRNA            complement(759..842)
                     /locus_tag="ACF3UF_002172"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="ACF3UF_002173"
     CDS             1370..1870
                     /locus_tag="ACF3UF_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3672257.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="ACF3UF_002174"
     CDS             complement(2060..2404)
                     /locus_tag="ACF3UF_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFD3672258.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2558..3478)
                     /locus_tag="ACF3UF_002175"
     CDS             complement(2558..3478)
                     /locus_tag="ACF3UF_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3672259.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3665..4156
                     /locus_tag="ACF3UF_002176"
     CDS             3665..4156
                     /locus_tag="ACF3UF_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFD3672260.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(4180..6555)
                     /locus_tag="ACF3UF_002177"
     CDS             complement(4180..6555)
                     /locus_tag="ACF3UF_002177"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFD3672261.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6881..7507
                     /locus_tag="ACF3UF_002178"
     CDS             6881..7507
                     /locus_tag="ACF3UF_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3672262.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7530..8234
                     /locus_tag="ACF3UF_002179"
     CDS             7530..8234
                     /locus_tag="ACF3UF_002179"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3672263.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            8426..9259
                     /locus_tag="ACF3UF_002180"
     CDS             8426..9259
                     /locus_tag="ACF3UF_002180"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFD3672264.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            9456..11384
                     /locus_tag="ACF3UF_002181"
     CDS             9456..11384
                     /locus_tag="ACF3UF_002181"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3672265.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            11522..11977
                     /locus_tag="ACF3UF_002182"
     CDS             11522..11977
                     /locus_tag="ACF3UF_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFD3672266.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            12057..12185
                     /locus_tag="ACF3UF_002183"
     CDS             12057..12185
                     /locus_tag="ACF3UF_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672267.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
BASE COUNT         3729 a         2322 c         2226 g         3975 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat aaaaatgttc ttattagatg
     2521 taatagatta aatttattct aaaataaacc tgattcctca ttttttttgt gaacgatttt
     2581 ttatttctgg caatacgcca gttgttcgat acattttttg ttcgttttca tttgcaaacc
     2641 ggccaaatac tgaatgagtt ggtaaaatat tgataaatgc atcgtcgtcg atttcatgaa
     2701 cgatctgatc aagatcatac atttcgtagc gggtgatgac catcatgatc atgttccctt
     2761 gtttttttga atagccaccg acagacggca gtaatgtcat tccacgtacc atccgttttg
     2821 ctagttcttc tgttacctct tctggcttga cggtaacgat cattgctgtt actttttgat
     2881 gactcgtgtg gatggcatca attacttgag tcattgcata aatggaaata atcgtataca
     2941 aggcactttc ccagttaaag aagaagcctg cgatgactac aatgatacca tttagaatca
     3001 gcatgtagtt tccgactgtt tttccagttg tttgtgaaag tacaagagag atgatatcca
     3061 tcccaccagt tgtaaagccc atttttaaag ataatcctac gccaagacct aataaaacac
     3121 cgcctactag ggcattcatc aaaatattat cagtgatctg tccgactgga agcagcatcg
     3181 tcatcaccga tacacataca acattcacaa aactaaggat cgttgctcgt tttcctactt
     3241 tgagaaaccc taatacaaac acagggatat tcaaaagaaa aataaatgtt cctgtgtcta
     3301 tcttgatatg aaaccattca tataaaagcg aggaaatgat ttgagcgatc ccattcatcc
     3361 ctgcagaaaa gacattggct ggaatcaaaa aataatttaa agcgaccgca gcggtcaatc
     3421 cggttatcaa aataaccact attttcttta atctttcatt tttatgatac gcagtcataa
     3481 ttttactcac aagcacctct cccctacttt ggtattccaa atgtaagaat aacagtttat
     3541 ctattaaaat aaaatacttc gaactcaaat gagaagaatt ttagcaaaca ggtaagaatc
     3601 tgccctaatc ctatgataag atagatgtat ggtaaatatt tatatgtata tcaggagggt
     3661 tcctatggca aaagatgcta gcttcgacat tgtatcagaa gtcaatacag aagaagtaaa
     3721 aaatgcgatt cagcaaacaa caaaagaatt gtccaatcgc tttgacttca aggattctac
     3781 agtagaaatc aaattagaga acagcaatct agttgtattg agcgatgatg atttcaaaat
     3841 cgaacagatc aaagatgtat tatttggtaa gctgatcaaa agaaatgtgc caatcaaaaa
     3901 tatccatttt tccgaatcag aacacgctct aggtggcaaa gctcgacaaa ctgccgattt
     3961 ggtcaacgga atcgatcgtg aaaacgcgaa gaaaatcact acagctatca aaaatgaaaa
     4021 actgaaagta aaagcacaaa tccaagaaga tcagattaga gtgacaggta agaaccgtga
     4081 tgatctacaa gctgtgattg ctttattacg taaacttgac ttaccaatcg agttgcaatt
     4141 cactaactat cgttaatcaa aaaacgaggc tgacgtctgt cattcctcgt ttttttgatt
     4201 tactgcttct tttgataacc aaaaacgctg tattccttct tccaattccc caacacttcg
     4261 tacttctctt gctgtttgcc aatgttgtgg gaataaacgt cgataagaaa aactagaaaa
     4321 tcgttgatct gccaatacaa cgattccttg atccgccatg ccacgaatca ctcgaccacc
     4381 agcttgcaag actttgttca ttccaggaag ctgataagcg taagcaaatc caaggtgttc
     4441 cttctcatca taatatgatt tgatcagttc ctgctcatga ttcatctgcg gcaaacctac
     4501 acctacgatc atactgccga tcaatcggtc ccctctcaaa tcgattcctt ctgaaaaaat
     4561 cccgccaagt acgcaaaatc caatcaatgt ttcagcggga tttgtttgaa attttgttaa
     4621 aaatcgttcg cgttcttcct cattcatgtc cgtttcttgg attagcacat tgctgtcggg
     4681 atattgctgt ctgaatgctt ccaccgcaag atctaaatat tgataagaag gaaagaaaac
     4741 gaaataattc ccgacctttc catcagcaaa agcatgaatc gtctctacta attttgccag
     4801 actgtgttcc ctttttcgat aagtcgtctc taggtaattt gcgatgaaaa cttgctggtt
     4861 tccttctggg aaaggactcg gcagtttgta agccagactt ttttgtcccc ccagtgtttc
     4921 ctgataataa gagagtggtg aaaaactagc agaaaaaaga atactgcttt ttcctttatc
     4981 caacgactgc tcaagaaaca agcttggatc aatacaaaac tcttttacta tcagatcgcg
     5041 atacgttttt tcgactgttg tttcgtagtg atcatcataa aattcactga ccttcaaaaa
     5101 atgaagcaaa tcaaaataat aaggaagcaa ttgttcttgt gatgggtgct caggaaattc
     5161 tgccagccat tctttaattt tttcgcttaa ttgataacct gcctttacta aagattcagc
     5221 cggtgctttt tgatgatgat aatcccaatg atcttctttt gctatttctc ggatcgaatc
     5281 aaattctttt aatagtttgt tgaaacggcg atgaagtttt ttgaattcct ttggtatagc
     5341 ttccttactt cgtttcgttt tttcataaga tagttctgcc gaatacatct ctcgggaacg
     5401 attcaccaaa ttatgtgctt cgtcaatcaa aaacagatag tcctcgtttt tttcatcttc
     5461 aaaaaaacgt cttaaataaa cagttggatc aaataaataa ttgtaatccc caatgattac
     5521 gtcacaccag atactgacat ctaatgatag ttcgaaagga caaagtgtat gctttcttgc
     5581 ataagtttcg atgacttcac gagtgatctg attctcatga ttcaaaagat cccataaacc
     5641 ttcattaatc cgattgtaat aaccattggc atatgggcac tgatctggat tacaggtcgt
     5701 ctcatctaaa aagcagatct tgtctttcgc cgtcaaagtg acacttttta cttcagctcc
     5761 tgtatctttt aatgctgtca tagcatcttc agctacttgt ctagttattg ttttagccgt
     5821 tagataaaag atcttttctc cctcttcttc ccctacagct ttcaaagcgg ggaataacgt
     5881 agagattgtt tttcctgttc cggtaggtgc ttctacaaac aatttctgtt tcgtacggat
     5941 cgttttataa gcagctaccg ctagttcacg ctgacctttc ctatactcat catgggggaa
     6001 tttcaaagcc atcaaagagg cattgcgtac agtgcgccag ttttcttgaa aaacaagcca
     6061 ttctttataa tcttcagtca gctttttaaa aaaagtttct aactgctctc ttgtctgatg
     6121 ttcaaccttt ctcgtgatca cttcttctgc cgtctggaag taagtcaatt gcagatttat
     6181 ttcttgtaaa tcatgttctt gactatagat ataggcatac acccttgctt gatgaaagaa
     6241 aagttccact tgttctggtt ctaaatcttc aaatcgtggt tcggaggttt tgatttcatc
     6301 tatataataa ataccgtctc ttttgaaaat accgtctgca cggccttcaa cgatcaggta
     6361 atattcatct aattgaactg ttgtttttaa aaagacttct ttttcatagt tttctcccgc
     6421 atctttttgg agcttgcggt ggattctcgc tccttctaat gcagtatggt tacttttttt
     6481 acgattgtcg atacttccac gtcgcaaaat aaattctact aagtgccgca cagatatttt
     6541 tgactgtttg atcatttcca ccacctcttt ctctctaaga ttacctgaaa aaacctagtt
     6601 tagcaaaaag agctctcttt ccaaacataa aaaaacaccc tgctgattag gcagggatat
     6661 aggatataga atttggattt ttggatgaat ctaatgtaac aaggacatat taaaatgcta
     6721 tgaaaactta ctttccttct ctttagaata tccaaatact tttcatatag tctgataatt
     6781 cagataagta aagagaaata agtacctgtt tttgtttcct agcaatgaat gcgttatact
     6841 aatggatgaa agaagttttg gctatcaagg aggaatgcac atgcatatcg aaagattaaa
     6901 aacaggaatg attgaagaaa actgttattt ggtctacaac gaagaagcac ttttgatcat
     6961 tgaccctgga gaagatgcgg aacgaatcaa acaagaaatc aaaaaaacaa accaacagcc
     7021 ggtagcgatt ttgcttaccc atactcacta cgatcatatc ggtgcagtgg aacctttacg
     7081 cgcgtattat caaatcccag tttatgtcag cccactagag caaaaatggc taggtgatcc
     7141 gattttgaat ctttctggac tcggtagaca tgatgatatt gctgatgtta ttgtctcgcc
     7201 tgcagaatat gaatttgaaa tgaaaactta tactttagga aacatgtctt ttcgcgtcgt
     7261 ccctacccca gggcattcta taggaagcgt cagctttatt tttgatgatt ttgtcgtttc
     7321 tggcgacgcc ctgtttagag gaagtatcgg tagaaccgat ctgtatacag ggaatttaga
     7381 acaattactt catagtattc ggacccagct gtttgtatta cctgatgaat ttgcagtcta
     7441 tccaggacat ggcgatgcaa cgacgattga acaggaaaaa aggacaaatc cttttttcaa
     7501 tcgttaaaac gacttaggag gagaataaaa tgacagaaac tacactttat atcgtacgac
     7561 acggaaaaac gatgttcaat acaattgaac gagtacaagg ctggtgtgat acacccctca
     7621 caaagcaagg acaagaaggc attcattatt taggtcgcgg gttaaaaaat gtcgactttt
     7681 catttgctta ttctagtgac agtggtcgtg caatcgaaac tgcccgtatt attctaggag
     7741 aacattctaa gggaaaagaa attccttatt ttattgaaaa aaggattaga gaatggtgtt
     7801 tcgggtctct tgaaggtgga tatgacatgg aaatgtgggg tgtgatccct cgtgtattga
     7861 attttaaaac atatgatgaa atgtttacca cagaagtttc ttttgaacaa attgctaatg
     7921 ctgtatacaa cttagatacc gctgggtggg cggaaactta tgaaacattg cgagaccgtg
     7981 tatggacagg atttgaagat atcgcccatc actgcgaaaa aaatggtggt ggaaatgttt
     8041 tagtcgtatc tcatggtttg acgatcgcct ttttgcttaa tctgatcgat cctaaacagc
     8101 ctgttcgtgc tgggctttta aatggcagcg taacaaaggt cacttatgca aacggtcgat
     8161 tttctatcca cggcatcaat gatacgtctt atatcgataa cgggaaaaca catagtcgcg
     8221 actcgtttct ataatgggga tattttaatt tttaccagag aatcataaaa ggcaaagtct
     8281 gaacgagggc tttgtcttct tttttctctt cgtgtactta tctgctttat ttctcaagtt
     8341 tttcttaata ttaaaaaaca gattgggttt ctcaaaaaat aacggtatac tataagatgt
     8401 atcttaattg ggaaggaagg aatttatgtt ttttgcaaat attatcaaag cagtgattct
     8461 cggtattatt gaaggaataa cggaatggct gcccatcagt agtactggtc atttgatcct
     8521 agcagatgaa ttcatcaaac tggatgccag ttcacaattt atgtcgatgt tcaatgtcgt
     8581 tatccaatta ggggcgatct tggctgtcgt cgttctttat tttcacaagt taaacccatt
     8641 ttctccaagt aaatcaacgg tagaaaaaaa agatacgtgg acactttggt ttaaagtgat
     8701 cgttgcttgc ataccagcca tcatcattgg tttgcctttg gatgattggt tagaagcaaa
     8761 tttccacaag ttcttaccag ttgccattgt tttgatcgtt tacggtattg cctttattat
     8821 tgtcgaaaaa cgcaacaaaa acaaaacacc tcgttggact tctctgaatg actttacgta
     8881 ccaagcagct cttcttgttg ggttattcca agtcttggca cttgttcccg gaacatcccg
     8941 ttctggcgca acgatcctag gatctatctt gattggtgct tcgcgttttg tcgctacaga
     9001 gttttcattt ttcttaggga ttcctgtcat gtttggcgca agcggcttga agatcgtcaa
     9061 atatttagct gaagggaatt cattcaaaat ggaagaaact gttgttcttc ttgtaggaac
     9121 attcgtatct tttgtggttt ccgtcttagc tatcaaattc ttactaagct atttgaagaa
     9181 aaacgacttt accgcttttg gctggtatcg tattatcctt ggtatcattt tgattggtta
     9241 ttggtttatt gcaatgtaga aaaaaccaga acacttctct tatttgagaa atgttctggt
     9301 tttttatttt ctttaataat aatcattata aataataaaa acaacatcaa gcttaatcac
     9361 caaatgataa ccattatcgt tctcatttag ctgttattat tatcaattac atttttatta
     9421 tgctatcctt gttttgacaa ggaggtctaa taacgatgac taatcagaaa aaagcttttg
     9481 cagcaacaat cggctgcctt ttatttatga tcttcggttt tatcttcgac cgattctctc
     9541 ttaccatcac cccacttttt tatatcagtg ccattatcat cggtggatat aaacaaacat
     9601 cggaaggctt gaaagaattg tggaatgatc ggacactgaa tgtggattta ttgatggctt
     9661 tagctgctat tggtgcctgt ttgatcggta attactttga aggagcaatg ttgacattca
     9721 tcttttgttt aagcggtgca ttagaggaat acacaactaa taaaagtcaa aaagaaatta
     9781 ctgctttgat gaatcttcaa ccacaaaaag cccaattatt aaaagaaaat ggacaaatgc
     9841 aagaagtaga tgtttctcaa ctaaaggtgg ataacttggt atttgtcgct aaaggagcag
     9901 ctgttccgat agatggcttt ttagaaagca cacaggcaac gatcgatgag tctgcattaa
     9961 gcggtgaatc tgtgcctgta gaaaaatatt taggcgatga gatgtatgca ggaacgctga
    10021 atcaaggaaa tcccatcacg attcgagtaa caaaaacgag ttccgaaact gtctttgcta
    10081 agattatcca attagtagaa gaagcgcaga atacgccaac tcaaacagct tcatttatcg
    10141 aacgaatcga aaataattat gtaaaattga ttttgcttgc tgttcctcta atgatccttc
    10201 tcccccactt tttcctaggt tggagttggg atgaaagctt ttatcgagga atggtattat
    10261 tagttgtggc ttctccttgt gcgcttgtcg catctgctac accagcttct ctagctgctc
    10321 tttcaaattc tgcaaaaaat gggattttaa tcaaaggcgg tatccattta gaaaagcttt
    10381 ctgaattaaa agcgattgcc tttgataaaa caggaacgct cactaaagga aaaccagttg
    10441 taactgacag ctttttcttt gatgaaaagg atttggcaca acaacttctt gttgctatgg
    10501 aacaaaaaac gacgcatcca cttgctcatg cgattttgca atatttcgat tgcacaatac
    10561 ctgaagaaat ccaatactta ccaatagaag aaattactgg ttttggatta caaactacct
    10621 atttaggtgc gcaatggaaa gttggcaagc acgcatatga tcctgagacg atgataatca
    10681 gcaaagagat tgcggaaatg atcgaacgtt tggaaaatca aggcaaaacc gtgatttatc
    10741 tttctaaaga tcagcagtta attgctgttt taggtctgct agatattcca aaagcaaata
    10801 cccaacaagt aatttcctac tttaaatccc aaaacatcca tacaagtatg ataaccggcg
    10861 accattctgg cacagcaaag gccattgctg aacaagtagg gattgaacat tactatgcaa
    10921 gctgtactcc ggaagaaaaa acacaactag tcaaaaaaga gaatgaactt taccaagtaa
    10981 atgcgatggt tggtgatgga gtcaatgatg cgcctgcttt agcagccgct tctttaggtg
    11041 tcgctatggg gcaagggaca gatgccgcta tggatatcgc agacatcgtc ttaatgaaaa
    11101 gcgacttaaa taaatttgtc tacagtcatc ggctatcttt aaaaatgcgg cggatcatca
    11161 aacaaaatat tattttttcg attcttgtta ttctcttgtt gattgcttct aacttcctgc
    11221 aatttttaaa tctacctctt ggagttgtag gacacgaagg aagcacaata ttggttattc
    11281 tgaatggctt gcgtttacta agacctttac ctgatctttc tgattcttca aaaaaatgta
    11341 agtcttgtcc actatacaaa gcgcggctgt cttctgtcaa ataagcaaag tgttttttta
    11401 tgattttgtt tattttatga aaaaaacagc ttatgaatag gtcttgaagg atgaattcct
    11461 acttttgtaa ctttctaaaa acatgttatg attgtttcga agaaagtgag gaatatattt
    11521 catggaaagt tggctttttt taggaattat tttacttgta gcaattttag ctaaaaatca
    11581 aagtctgatg atagcggcag cttttgtttt gattatgaag ctcataccag cctcccgttc
    11641 ctttttccct tggcttcaag gcaaaggaat caatattggg gtgacgatca tcacagcggc
    11701 tattctaatc cctatcgcaa caggagaaat cggtctacgt gatctattag aagcctttaa
    11761 atcccctatt ggctgggtag ctgttttttg cggtgggcta gtggctgtct tatcttccaa
    11821 gggtgtagga ttgattgctt ctgatccaca aatcactgtt gcacttgttt tcggcacgat
    11881 tttaggtgtt gtcttcttaa gaggaatcgc cgccggaccg gtcattgctt ctggtatcac
    11941 ttactgtatc ttacaagtat ttgctttagg aaaatagaac aaattttgtc tattttagga
    12001 gattcttaac acccccaatt tactgatccg tgatatactg acaacgaggt gatacaatgt
    12061 tcgaaaaatt aaagtatttc ataggaacaa tcggctggtt tcttctagcg gtacttttga
    12121 ttctgggctt agcttatcta ttatttcctg atttgataca aaatgtgttt gatactgctt
    12181 tttgattgac ctattaaaac gatatagggg atgctcctgc gatgcagggg ctttttttaa
    12241 tcaatgtttt gt
//
LOCUS       DAXLPY010000070        12136 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.070, whole genome shotgun sequence.
ACCESSION   DAXLPY010000070 DAXLPY010000000
VERSION     DAXLPY010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.070"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..610
                     /locus_tag="ACF3UF_002184"
     CDS             <1..610
                     /locus_tag="ACF3UF_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3672268.1"
                     /translation="KRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWIQLIL
                     DEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSKITVF
                     PKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAYTIQN
                     ATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            723..1001
                     /locus_tag="ACF3UF_002185"
     CDS             723..1001
                     /locus_tag="ACF3UF_002185"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3672269.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            1119..1355
                     /gene="secG"
                     /locus_tag="ACF3UF_002186"
     CDS             1119..1355
                     /gene="secG"
                     /locus_tag="ACF3UF_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFD3672270.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            1458..2213
                     /locus_tag="ACF3UF_002187"
     CDS             1458..2213
                     /locus_tag="ACF3UF_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3672271.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            2216..4573
                     /gene="rnr"
                     /locus_tag="ACF3UF_002188"
     CDS             2216..4573
                     /gene="rnr"
                     /locus_tag="ACF3UF_002188"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFD3672272.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            4595..5059
                     /gene="smpB"
                     /locus_tag="ACF3UF_002189"
     CDS             4595..5059
                     /gene="smpB"
                     /locus_tag="ACF3UF_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFD3672273.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            5361..6080
                     /gene="atpB"
                     /locus_tag="ACF3UF_002190"
     CDS             5361..6080
                     /gene="atpB"
                     /locus_tag="ACF3UF_002190"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFD3672274.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            6133..6348
                     /gene="atpE"
                     /locus_tag="ACF3UF_002191"
     CDS             6133..6348
                     /gene="atpE"
                     /locus_tag="ACF3UF_002191"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFD3672275.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            6439..6963
                     /gene="atpF"
                     /locus_tag="ACF3UF_002192"
     CDS             6439..6963
                     /gene="atpF"
                     /locus_tag="ACF3UF_002192"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFD3672276.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            6950..7492
                     /locus_tag="ACF3UF_002193"
     CDS             6950..7492
                     /locus_tag="ACF3UF_002193"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFD3672277.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            7515..9071
                     /gene="atpA"
                     /locus_tag="ACF3UF_002194"
     CDS             7515..9071
                     /gene="atpA"
                     /locus_tag="ACF3UF_002194"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFD3672278.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            9085..9987
                     /locus_tag="ACF3UF_002195"
     CDS             9085..9987
                     /locus_tag="ACF3UF_002195"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFD3672279.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            10010..11416
                     /gene="atpD"
                     /locus_tag="ACF3UF_002196"
     CDS             10010..11416
                     /gene="atpD"
                     /locus_tag="ACF3UF_002196"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFD3672280.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            11430..11852
                     /locus_tag="ACF3UF_002197"
     CDS             11430..11852
                     /locus_tag="ACF3UF_002197"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFD3672281.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4036 a         2155 c         2676 g         3269 t
ORIGIN      
        1 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
       61 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
      121 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
      181 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
      241 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
      301 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
      361 ttactcctta aagcaagcat cagctacgag acagcttggc agcaaccatc tgcctttatt
      421 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
      481 tgctacggca ggggataaag cactgctgct tgttccagaa gcagaacact tggaagcatc
      541 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
      601 gatggattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
      661 tctggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
      721 atatggaaat caaagaagaa aaaaatcgtc ttgctttatt caatgatgag caacaagaga
      781 ttggagaaat gacatggtca gatgcgggcc cagacatcat gatcattgac catacatttg
      841 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
      901 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
      961 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     1021 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     1081 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     1141 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     1201 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     1261 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     1321 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     1381 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     1441 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     1501 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     1561 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     1621 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     1681 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     1741 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     1801 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     1861 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     1921 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     1981 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     2041 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     2101 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     2161 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     2221 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     2281 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     2341 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     2401 agtgaaactt cctttaaaac caatcttgat cgaaggaaca tttcgagcaa atgaacgagg
     2461 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     2521 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     2581 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     2641 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     2701 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     2761 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     2821 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     2881 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     2941 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     3001 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     3061 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     3121 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     3181 tgtatatttg actgatcgag tgattccgat gatcccgcaa cgtttatcga atggtatctg
     3241 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     3301 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     3361 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     3421 tcagctcgta cctatgttcc aagaaatggg tgaattgcat cgaatccttg aaacgatgcg
     3481 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     3541 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     3601 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     3661 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     3721 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     3781 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     3841 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     3901 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     3961 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     4021 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     4081 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     4141 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     4201 aggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     4261 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacaaaaag tgcgcgtaaa
     4321 agtagtcaaa gctgatccag atgaacgagc agtggatttt gaactcgttt ccgcagaaga
     4381 ggtcactgcg ttggaacgtc caaaagcacg caatggaaaa tctggaaaac gagaaggaaa
     4441 acaagcaggc aaacgctcag aaaaaaatgg caagaagaac aaacgatata gtgatagtaa
     4501 gcaaacgttc ggtaagaaaa aagggaaaaa gccattttac aaagatgtca aaaagaagaa
     4561 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaactaat
     4621 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     4681 ggtcttgcaa ggaacggaga tcaagtcgat acgaaacagc cggatcaatc tgaaagatgg
     4741 atttattcgc gtccgcaacg gggaagcttt cttgcataat gttcatatca gtccttatga
     4801 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaagaa
     4861 acaaatcgtt cgtcttgaaa acgaattgaa aaacactgga atcactgttg ttcctttaaa
     4921 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcaaaag ggaaaaaatc
     4981 gtatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     5041 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     5101 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcac aggttttttc
     5161 ttagatcagg agcaccgtgc atggggaaaa attcgcttcg tttttgactg aaataaaaaa
     5221 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     5281 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     5341 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gtttcacatt ggaccaattt
     5401 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     5461 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     5521 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     5581 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacataggtt
     5641 tagtaacaaa aatcgtctta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     5701 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     5761 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     5821 ttccgatgaa actgattgaa gaatttacaa atttattaac acttgcttta cgtctttatg
     5881 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     5941 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     6001 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     6061 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     6121 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     6181 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     6241 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     6301 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     6361 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     6421 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     6481 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     6541 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     6601 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     6661 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     6721 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     6781 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     6841 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     6901 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     6961 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     7021 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     7081 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     7141 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     7201 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     7261 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     7321 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     7381 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     7441 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     7501 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     7561 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     7621 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     7681 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     7741 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
     7801 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
     7861 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
     7921 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
     7981 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
     8041 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
     8101 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
     8161 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
     8221 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
     8281 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
     8341 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
     8401 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
     8461 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
     8521 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
     8581 cggttgatgc cggactatct gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga
     8641 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
     8701 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
     8761 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
     8821 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
     8881 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
     8941 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
     9001 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
     9061 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
     9121 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
     9181 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
     9241 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
     9301 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
     9361 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
     9421 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
     9481 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
     9541 tctgatcagc caagctttga tgaagtccgc aaaatcgtaa atatggcaac aactatgttc
     9601 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcactaact
     9661 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
     9721 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
     9781 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
     9841 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
     9901 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
     9961 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    10021 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    10081 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    10141 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    10201 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    10261 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    10321 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    10381 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    10441 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    10501 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    10561 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    10621 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    10681 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    10741 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    10801 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    10861 attacaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    10921 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    10981 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    11041 ggcttcttct tcaagtgctt tagcacctga aatcgtgggg gaagaacatt ataaagtagc
    11101 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    11161 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    11221 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    11281 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    11341 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    11401 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    11461 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    11521 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    11581 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    11641 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    11701 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    11761 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    11821 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    11881 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    11941 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    12001 tggaacaccg tatatcagag gttgtaaaat cagcgttttg tcctgagtat tagagaaaca
    12061 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    12121 tgaacaccgt ttattt
//
LOCUS       DAXLPY010000071        12127 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.071, whole genome shotgun sequence.
ACCESSION   DAXLPY010000071 DAXLPY010000000
VERSION     DAXLPY010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.071"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..884
                     /locus_tag="ACF3UF_002198"
     CDS             <1..884
                     /locus_tag="ACF3UF_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFD3672282.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            932..3061
                     /locus_tag="ACF3UF_002199"
     CDS             932..3061
                     /locus_tag="ACF3UF_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFD3672283.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3036..3725
                     /locus_tag="ACF3UF_002200"
     CDS             3036..3725
                     /locus_tag="ACF3UF_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672284.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4133..4819)
                     /locus_tag="ACF3UF_002201"
     CDS             complement(4133..4819)
                     /locus_tag="ACF3UF_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3672285.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4955..5149)
                     /locus_tag="ACF3UF_002202"
     CDS             complement(4955..5149)
                     /locus_tag="ACF3UF_002202"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672286.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5199..5639)
                     /locus_tag="ACF3UF_002203"
     CDS             complement(5199..5639)
                     /locus_tag="ACF3UF_002203"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFD3672287.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5643..6488)
                     /locus_tag="ACF3UF_002204"
     CDS             complement(5643..6488)
                     /locus_tag="ACF3UF_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFD3672288.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLEKQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6637..8055
                     /gene="pepV"
                     /locus_tag="ACF3UF_002205"
     CDS             6637..8055
                     /gene="pepV"
                     /locus_tag="ACF3UF_002205"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFD3672289.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(8131..9333)
                     /locus_tag="ACF3UF_002206"
     CDS             complement(8131..9333)
                     /locus_tag="ACF3UF_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672290.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
     gene            complement(9320..11107)
                     /locus_tag="ACF3UF_002207"
     CDS             complement(9320..11107)
                     /locus_tag="ACF3UF_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6020 family protein"
                     /protein_id="HFD3672291.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            complement(11120..12073)
                     /locus_tag="ACF3UF_002208"
     CDS             complement(11120..12073)
                     /locus_tag="ACF3UF_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3672292.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
BASE COUNT         3931 a         2241 c         2407 g         3548 t
ORIGIN      
        1 gtatttcagt accggttgca ctgttctcat ttatgggctc gattatggct ggaatctttg
       61 ctaatatcgt caatttcaaa caatatcaaa cgatttatgc tggtttcaat ccagcggctg
      121 aaagctatac ttataatgac tatttccaaa ttggtatgat tgggatgatt gtaagcttag
      181 ttgtggtact aacggtcgct aatatatcaa tgaacaaaaa gaaacgctat gcaatggcag
      241 caaacgtacc agctgaaggt ggcgacgcac caatgatctc atggttagcc gtattattac
      301 cagttttagg ggtcgttctt ttagatcttc aaatcatctt aggttttatt ctagcaggta
      361 tctgggcatt gctgtttact ggaaaattgc gcggaggtta taaagaaatc tgtcgtcagt
      421 ttgcgaaatt atttacagat ggcgcagtcg atgttgcacc aatggttggt ttcttgatga
      481 ccttagcgat gttcaataat tcagctgcgt atgcttctcc ttatttttca gctatttttg
      541 gagattggat accgcaatca ccattagtct tggcaatcgt atttgctata ttgacaccac
      601 taggattttt ccgcggtcca atgaatctag tcggttcagg ctcagctatt ttagctgtcg
      661 tgttagctgt taatccaacg atgtcgccag cctttttgtt cccgttattt gcaattacaa
      721 cgattgctcc tcagcattta gatattacac aatcttgggt tgcttgggga ttaggttata
      781 caaaagtaac ttctcgagaa tatatgaaga aatccatccc aactggttgg atcatcggtg
      841 cgatcttatg cctgatcacg ttcttattgt acgggaacgc ctagtaaaca aaacgtcgat
      901 aaaaacgatt agataaatgg aggaaaagaa aatgaaacgt tttgtgcgaa tgggaattga
      961 tgttggcggt acacatacga aagcagtcgc aatcgataat gcgacgcacg aaatcatcgg
     1021 aaaatcttca gtgaaaacaa cccacgatga tgtccgtgga gtagctgcag gtgtcgttca
     1081 gtcttttcaa aattgtttgc gggaaaataa tatcagtcca gaagatgttg tgtttgttgc
     1141 acattctacc acacaagcga ctaatgcact gattgaagga gacgtagcaa aagtcggcgt
     1201 aatcgggatg gcaaaaggtg gattagaagg ttttttagca aaacgacaaa ctagattgaa
     1261 cgatatcgat ttagggaata agaaaaaaat agagattgtc aatgcattct tacctgtcaa
     1321 aaacttaaat gtagaccgtg tttcagaaac gatttcttct ttagaaagag aaagagcgga
     1381 ggtcttggtt tcttctatgg catttggagt agataatggg gaaccagaac gagttgttta
     1441 tgaagcagca tctgtgaaag cgatccctac aacgatggct tctgacatca caaaattata
     1501 tggattgaca agaagaactc ggacagcagc aatcaacgca tctattttac caaaaatgct
     1561 agatacggca acctcgacag aagactccgt acgagaagca ggggtcaatg tttctttgat
     1621 gattatgcgc ggagacggcg gagtaatgga aatcaatgaa atgaaaaaac gacctgtttt
     1681 aaccatgctt tccggtcctg ctgcatcagt catgggctct ttgatgtact tgagagcgtc
     1741 taatggtgtt tattttgaag taggcggaac aacaaccaat atcggggtca ttaaaaatgg
     1801 acgtccagca atcgattatt caattgtagg tggccaccca acatatatct cttcattaga
     1861 tgttcgggtt ctaggtgtgg caggcggttc gatggtacgg gctaatcagt caggaatcat
     1921 cgatgtcggt ccacgttctg cacatattgc cggtctagat tatgcagtat ttacggagac
     1981 agaaaaaatc aaaggtccta aggttgaatt tttctctcct aaagaaggag accctgctga
     2041 ttacgtcaag gtagtgatgg aagacggaga agaagtgact attacaaata catgtgcagc
     2101 caatgttctt ggattagtgc aagaagaaca tttttcttat ggaaatgtcc catctgcacg
     2161 aaaagccata caggcattag cagactattg tcatacgacg gttgaagaca tcgcagagca
     2221 gatcatggaa aaatcctatg ctaagattga accggtgatt ttagaattgg cagacaagta
     2281 tcacttggag aaagatcaga tttctcttgt aggtgtaggg ggcggcgctg cctcattgat
     2341 tacttacttt agtaataaaa tgggtgtgaa atattcgatt cctgaaaacg ccgaagtgat
     2401 ttcttctatt ggtgtagcac ttgcaatggt ccgagatgtt gtagaacgta tcatcccttc
     2461 gccaagtaaa gaagatatac gatcgttgaa aaatgaagcg atgaataaag cgattgaatc
     2521 aggcgctaca ccagaatcga tcgaagtcca cgtagaaatc gatccacata cttcaaaagt
     2581 aacggctatc gctactggtt ctacggaagt gaaagcaacc gatctaacca aggagatcac
     2641 aacagaagaa gcactagagc ttgctgcaga ggatatgcga ttaaataaaa atgaagtttg
     2701 cttattggaa aatacacctt tcttttatgt atgcggcgaa cagaatcgtt caaaaaatgc
     2761 tggaagtctt cggatcatcg atcaaaaagg atttatcaag gtccaacgtg gacatgcttc
     2821 atgtatgaaa acaactgcag ccaattatat gacagctgtc gaacaacttt gggaagatat
     2881 ggcagtttat caaactgaat tgattgcccg accagaattt tatctctgct taggagcaag
     2941 agtctctgat tttacagcga cggatctgga acaactacag cttttgatgg atctggaagt
     3001 atctactatg gaaccggagg aagaagtgat cgtcgttgcc ggaaatatca aacaaacata
     3061 agttagaaga gttactaaac gaattacaac agatccccga agaaatttgg ggattctacc
     3121 agtttcggcg agatttattt tggaaaaaga ttcctttgtc caagcagaaa attcttatac
     3181 aacaatcaat cgattgtggt atcgaaacgg catgtagcat caaaaaaaag tacccttttg
     3241 ccgatgtagg agaaatctgt gaacaaatgg ctgttccaat cgtttcctgt gaatcagagc
     3301 aaataaacga acgaatcact tttgcaactt atgcagaaga tgaagggatc cgattgatga
     3361 cggagccgtt agaaaaatta aaatgttcag gactagcttc gatctctaaa gaaacagcgc
     3421 aagctttgat tattggacat gaactatttc accacatcga agcttctgtt aagggaattt
     3481 atacgcaaag cgaaaaaatt gtgctgtggc ggttgccttt ttatacacat caatcaaaca
     3541 ttcgtgcatt gagcgagata gcagcgatga gtttttcaaa agagatgaat caaagcgatt
     3601 tttcgcctta tgtattagag gcagtcttac tttggccata taatgaaatt cgtagccaag
     3661 ggatcttaga agaaataaaa gaaatagaaa aaagatgtac ggagtatgat ttagattaca
     3721 aataaagaga ctgtgacaaa agtcgtgtca cagtcctttt tttccgaata aacggtgttc
     3781 tcctgtcaac tcctcggtca caagtcaaaa tattcaacaa acatgagaag ctgttttttg
     3841 aaattgttcc ttgtgactcg gagatgaacg gcaggctcac gacctcttgg aaaaaggtgt
     3901 tcaaaagctt gcatctgcgg taataagaac agccaagtta aaaacataag aagctatttt
     3961 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct caataaacgg
     4021 tgtgcaatca gctgaccctc ggtattagct caaaaaaaac ggcaaaatat gaggaactat
     4081 tttgccgttt atttctctaa tactcaggtc aaaacgctga ttccaaaacc tcttatttga
     4141 tgggtctgtc ctgaatatct tcaaaataat cggggtaatt atgaatcacg tattcttgct
     4201 cctcgataat catatgtaaa tgcatcgtgc aaagaaatcc gacttcatca aagttatgat
     4261 caatcattga ttgaagcatt gtctgatgtt catctaatac tcgaccccag tctaattctg
     4321 aaatcgtcaa acgtaaccat ctgaaacggt tcaagtgcgt actataactt tctagccaat
     4381 cccaaatttc tcgttttcca gcaatttcat aacaagttcg gtgaaaatca gtatccaaat
     4441 caaaaaaagc ttttttattt tgagcgatca ctgcctgatc ggtttgttct agtatttttt
     4501 ctagtttagc ttgatcttgc ttggtcattt tcgcactgca ttcttgcagg atcggttttt
     4561 ccaacttttc ccgcgtataa cgggctaatg aagcagatcg gatatcgatt tttgaaacat
     4621 aagtgccgga ctgtggaatg gtttttacaa gctcttgatt gcgcagttgg atcagtgctt
     4681 ctcgaatcgg tgtacgcccg atagctagtt gttcttctaa cactttatcg gagattttac
     4741 ttccaggtgc taactcggaa taaatgattt gtttacgtat agattcataa gcttgctgtt
     4801 gcaaattatt gataaccatt taaccttcct ttctatgcag atataatcta ttataacata
     4861 aatcgcttac aaatcgtgtg ggcataaaaa cacagtctgc aaaaaaagcc ctgataggca
     4921 tgcctattag agcctcgaaa agaaaaatat tgaatcaatc tggtcgtacc tcttggatcg
     4981 gtttgacacg accgccgatt cttttagcaa aagcttcgga ttcttttttg tctttgaaaa
     5041 tgagcagatt gtctaagttt ttttcccgag tgcgacagcc agttttatcg atgtaaccgt
     5101 gcattacttt aacgacatac atggggatca cctgcttttt tcttttcatt atacgaacta
     5161 ctcgacacaa tacaagaaaa atgcttagac ggtctttatt aagaatttac atcatccaaa
     5221 gaagcgtacg cttggaataa ctgttctaac tccggattga ctttgctcag cttcactaat
     5281 cgttgcgaat cagaaagtaa aaaacagtgt ttactactgc cagtagtttt taattttttg
     5341 tcttcagttc ccacaatttc gtagctaaaa tccaaccgtg ttcccgtata cttttggata
     5401 gttgggtgga tgctcacttt ttctccgtaa tggatcattt ctttatagct gcaatttact
     5461 tccagaacgg ggatgatgat cccagattct tcgatttttt tatagggaaa ccctagatgt
     5521 accaataagg ctacccgagc ctcttcaaac cagcggatat aattgctgtg atgaataatc
     5581 cccatttgat ctgtttcata ataaaaaggt tctcgcacat aacctgtaaa tttctccatg
     5641 actcatgcct cgttttccat tgatttttta caaaaataat tcatccactt cggaagtgct
     5701 tcgctgattt gtgtcggcaa aacaatatat tgttcttttg ccagctggtc tccaatgaaa
     5761 ctatgaagat aaacagctgc tgcaatcgtt tggtcatttt gaggaaactg ggctaaaaat
     5821 cctgtgatca tcccagctaa agtgtcaccc atgccgcctg ttgccatagc agcagaacct
     5881 aaaggattgg tgtagaagtg ctggtgacca taaatttttg tctcatgact tttcaaaacg
     5941 agcacagcac cgatttcctg ttgcttcttt ttgttttctt tatcccgttg ttcttgtatc
     6001 ggtagagaac tcaaccgttg ccactccatt tgatgaggtg taagtacagt ttgttcggga
     6061 tagggtagca aaagatgatt agcaacaagt aaacttaaag cagagccatc aatcaccagc
     6121 cattgttctt ttgattgttt ttctagtact tgtttgaaac gttccaaact cttagaagaa
     6181 gtacccaatc cgggaccaat caagagtaca tctgcttgct ttattacgga aagaaactgg
     6241 tcagtatccg tccaatctac aatcattgct tctggcagat gactgtgaag agcactccga
     6301 tttttttcat cagttactac agtcgtgaga cccgctccac tgtgtacggc agctaaagca
     6361 ctcataatga ttgctccgcc atattgttca ttgccgccaa tcaaaacgat acgtccaaat
     6421 gttcctttat gtgaaatctt tggacgaggt gtgatgactc ttttcactag ttgttcgttt
     6481 atcagcatcg aaaaacctcc ttttactcat tatagcgtat atttttttta gagaaaaaca
     6541 gataagaaaa ggaattgtca gattttttga actatttttt tctgtaattt gtggtatcat
     6601 gaacacgaag acttaaataa gtggaggatt aactttatga caattgattg gcaaaaagaa
     6661 gtagaagcac gtaaagaaga cttgcttgaa gacttgaaaa atcttttacg tgtcaacagc
     6721 gagcgcgatg attcaaaagt aacaccagat gcaccatttg gacctggacc tcgcgacgca
     6781 ttgaaacata tgttagctta tggcgaacgt gatggattta aagtaaaaaa tgtcgataac
     6841 tatgcagggc atattgatct tggcgaagga gacgaaacgc tagggatatt tggacacatg
     6901 gatgtcgttc ctgcaggaga tggctgggac acagatcctt atgaaccagt aatcaaggat
     6961 ggaaagatct ttgcacgcgg atcaagcgat gacaaaggtc caagtatggc agcttactat
     7021 gcgatgaaga tcattaaaga acttgacttg aaactatcaa aaaaagttcg cttcgtagtc
     7081 ggcagcgatg aagaaagcgg ctggggcgat atggcttatt atttcgaaca tgaagaagaa
     7141 ccagattttg gtttctcacc agatgctgaa ttcccaatca tcaatggtga aaaaggaaat
     7201 gtttctttag ctttacgctt caaaggcgac aatgcaggag attatgtctt gaaatctttt
     7261 gtttccggac ttcgcgaaaa tatggtgcca ggaacagcaa ctgcagcact tcaagtacca
     7321 agtgcagatg cagctatcgc gatggaagaa gcattttacc aattcatcga agcaaatcca
     7381 gtaagcggaa cgattgaagc ggacaatacg tatgtaaaaa tcgaattagt tggtaaaggc
     7441 gcacatggtg caagcccaca atctggtatc aatgcaggtt ctttcttggc attgttctta
     7501 gataactatg aattcctagg atctgctaaa caatttatcc atgtagcagc tgcttatgtc
     7561 catgaagatt tttatggaga aaaactagga gtcgcttatg aagatgaaaa aatgggcaaa
     7621 ttgacaatga atgctggact atttgctttt gaagaaaatg gtacagagga agcgaacttc
     7681 atcaatatga atttccgttt tccaaaaggt gtaacagtag acggattgca aagtgacatc
     7741 gaacaaacag tggggcaaga aggcgcaaca gttactcgag gtgctcgcgt aatggaacca
     7801 cattacgtac caatggatga tccattggtg gctacattat tgcaagtcta tgaagaccac
     7861 actggagaaa aaggctacga acaaatcatc ggtggcggaa cttacggacg tttgttgaaa
     7921 cgtggcgttg cttatggagc gatgttccca ggatatactg atacaatgca tcaagcaaac
     7981 gaatttatga gtcttgatga cttgttcaga gcaacagcaa tctatgcaga tgccatctat
     8041 cgtttggcga aataaaaata ctaaaaaact ccggctatct ctgacagctg gagtttttat
     8101 gtttaaaaat gaattagtac atcggtattc ttaaaagtaa tttagttcgt cttttgattt
     8161 ctcaggaggg atcaaaaagg cgaaagcact aagtatagca aaacttgtga tgatttgcgt
     8221 acgatacgta aaccaataat gaatctgtga gtgattagct aaaatattgt accaaatata
     8281 cggcgttaca gcagctaaaa caaacaaaac tagaagttgg aacggacgcc agctatttcg
     8341 tttacgataa gcaaaataga gaaaaacaag acaagtaatc aatagcaata atattgctac
     8401 ttttggatac atcaatctaa tattgctttt cagcatctct aatcgatgca acgggtattt
     8461 gtcgtttcct tccgttcgaa agaggatttg gttgattgca tcttttacaa tgtttttgtt
     8521 caatatgatc gatgatagga tccatttagc cacccatgtc aaaccatagc ctaatcccca
     8581 aaagataccg gtaaaaacaa aactgcctac ttgtttgctc aatgaactgc gtttatccat
     8641 taaatactta tttgttacat aataaataat gatcacaggt atcccccaag agatgaccgg
     8701 tgttgtcaac aagtcaaaaa agttagctaa agaaccaatg acaaagaaat acaagaataa
     8761 ttgttggttg gtgttggaga gttgtggttt tgttaaaaat agtaatacag acaataaagt
     8821 caaaatccaa atatttgaaa attgcatact gaagaaaaag gttgcagcat ttcctatagc
     8881 aagcgaaatc aacaaggctg tcgttaaata gatgtcgcta cacttggtta aaaagtagct
     8941 cgtcaatcca atcagcagaa aaagaatggc tgcgtaaatc attcgaatac tccccaaact
     9001 catccctagc agtaaaggtc gtaaaaaaag ctgataacca tgccaataac ggggataatc
     9061 cgccatagac atcgcgttct ccaaggagtt caattcagga tctgcttttg tttttcgtat
     9121 catcaaatga tcagtaaaat tatctaaccg agtgcctagc atatttcctt gattgataga
     9181 aggatacatt ccttcttttt caaccatctg tagagatttt tctgcattcg attcaataga
     9241 gtgctgcgga atgaaaaaag taattgtcag tagtacgcaa tagctagcga tcaagagaac
     9301 aaaagcaaaa aatatctttt taaatagttt catgagtatc tcctatatct gttttcattt
     9361 tttctctttt atctagtaaa aaaggagaga ggatataaac aggtagacct aatgctaaaa
     9421 caaacacata ccgtaaacta aaagccacag gagtagcaat cataatagta gcaaaaacaa
     9481 gcataccggg aagaaaaagg agtaaatacc gatatttttt cttaaagatt gctaaaagtg
     9541 cactgccgat agctaaccac agtaatgtgc cggaaccaaa gaaatcacga gcatcgatga
     9601 tttttttcat tcctgacaat ccagtaagat gttcaatcaa atctacttgc ttcatcccat
     9661 aattattcgt gtttacacga gtatctaaaa agccgtaact attttttgta ccaggtaccc
     9721 agaacccgaa cgtttctaaa atataagcat ctgtatagat ttttatatta cttggtaaat
     9781 ttcttgccca tagtgataga aattcttttt tatgtgtatt caaaaactca ttgttaaaat
     9841 ttttatgcca cttgattgag tctgcaagac taggagaata cgcttcataa tcttttatcg
     9901 ggagtagctg attcatgaat gctttatctt tcttagacaa gtcaccatcc ataacaatag
     9961 ttctagaaat ttgctgcaaa ggaacaccta attgttcagc agtttctgta ggaatagcat
    10021 aacgagccat caacgggtgg atgagtagtc cagcaatcac tgtataaccc agcaccactt
    10081 gaaagaatgc ttgatacctt ttttgtttca aaataatcaa gccgcaaatc aaacctgtgc
    10141 cggttactac ataaatccca ttatttctta gataggtggt cagtaaagca aggatgatta
    10201 cgtaaatctg attgagaatc gttggctttt ctcgttgaaa aataaagtca aaaaccgcta
    10261 aggaaaataa aaagcaagcg atagagaaca aagtatcttt ttgcatgttc aaggcgtaga
    10321 ttggaaaaac cggtgcaaat gcaaaatagc ataaactaat gagtaccgga aaaaaatgga
    10381 tgtttctttt taacagccag caaagagaat aacttatcgc tgaagctgtt atcaatgttt
    10441 gaaaaatcga aaataaaaat acaccgtgat tgatcgtatc agttggtaaa tcatgaacaa
    10501 atagcttgac cagtaaggtg aataagactg gatgatgatt gcttatagga acatcaccca
    10561 tagattgggc gaccgaactt aacgaatcag gcaaaaccac tccaggatac aatgccaaca
    10621 gataaggaag ccaacacaga actaaaaaga cagtaaagaa taaaaaatat tttcttgaag
    10681 agaaagcctg tgtgttttga gcagtaaaaa atgtttccag ttttggcatt gataaataaa
    10741 tcgattgtaa aaataaaaaa gaatacacaa aaatggagaa ataaacaaga aagtaaaaaa
    10801 tacttccatc agcaatcgtt gtctttgtat agtttgctga gacatactga aattgtatct
    10861 gtctgccaat agaaagtgta agagcaaaag ctgcagaaaa aaacaatcgg gcaatagctg
    10921 caactttgtt ttttattgaa aacaactcta ttccatattg cttaaaagca agtagcaaaa
    10981 ccatggctaa accaatgatt actgttggat tcaaagttcc tagaccataa gaagtaaaaa
    11041 aagcaaaacc tgacgcaaat aaagttgcaa aaaaagtagg aaatagattc tcctttttct
    11101 tatgcataaa aaaggcctcc tacttcattt ctttattttg atattcgtgg tagacatggt
    11161 ataaattcaa ttcatattct ttcttggcat ttgtgacgac cgtatccaaa atcaaccctg
    11221 ttactaatga aagaagggct aaagtcatca atccagtact taaaatcgca gaagggatgc
    11281 gtgtaataaa gcttgtcagc atatattcac gaatcacagg aatccccatg accaatccaa
    11341 ataaaaagaa gaagatggtc cagatcccaa agaaaagcaa aggtttataa tctttgcaca
    11401 ttttgatgat catcatgatc actttgaatc cgtcagagaa tgtattcaat tttgattcgc
    11461 taccttcagg acgatcgcga taatcgattg gaatctcaac gaacttgaat tttttatcta
    11521 aagcatgaat cgtcaattct gtttcgattt gaaaaccaga actcataata gggaagcttt
    11581 tgacaaaaat tcgattgaat cctcgatagc cggtcatgac atcgcgaatt tttgttttat
    11641 ataagtaagt aattgtattt ttaaccagat tattcccaaa atcatggaaa ggacgcttat
    11701 tttcatcaaa ataggttcca tttgatagac gatcgccaat gaccatatct gcttcgccag
    11761 aacgtaattt ctcaagcaaa ccatgtgcag cttctgcagg ataagtatca tcaccatcta
    11821 ccatcaaata ataatcggca tcaatatcaa aaaacatttg acggattaca tttccttttc
    11881 cttgacgtgg ttctttcttt acgattgccc caccttgaac ggccaattcg tatgttcgat
    11941 cggtcgaatt attatcatag acataaatat ctgcttctgg taattccctt ttaaaatctt
    12001 caataacagt tgaaattgtc gcctcttcgt tataacaagg aatgagcacg gcaatttttt
    12061 cacgtgattc catttgtcac tctccttata taataaaact aatcttattt caagaatacc
    12121 atataat
//
LOCUS       DAXLPY010000072        12122 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.072, whole genome shotgun sequence.
ACCESSION   DAXLPY010000072 DAXLPY010000000
VERSION     DAXLPY010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12122
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.072"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..258
                     /locus_tag="ACF3UF_002209"
     CDS             <1..258
                     /locus_tag="ACF3UF_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672293.1"
                     /translation="LKRKVTDRNKNLLNVVMICYISFLILGLPQAVFPEMFSGDWGIV
                     SYSILTLIAMVLGTSFYNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            465..653
                     /locus_tag="ACF3UF_002210"
                     /pseudo
     CDS             465..653
                     /locus_tag="ACF3UF_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1365..1970)
                     /locus_tag="ACF3UF_002211"
     CDS             complement(1365..1970)
                     /locus_tag="ACF3UF_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672294.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2152..2487
                     /locus_tag="ACF3UF_002212"
                     /pseudo
     CDS             2152..2487
                     /locus_tag="ACF3UF_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387932.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2652..2867
                     /locus_tag="ACF3UF_002213"
                     /pseudo
     CDS             2652..2867
                     /locus_tag="ACF3UF_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3005..3976
                     /locus_tag="ACF3UF_002214"
     CDS             3005..3976
                     /locus_tag="ACF3UF_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3672295.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4116..5429
                     /locus_tag="ACF3UF_002215"
     CDS             4116..5429
                     /locus_tag="ACF3UF_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFD3672296.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5472..6338
                     /locus_tag="ACF3UF_002216"
     CDS             5472..6338
                     /locus_tag="ACF3UF_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3672297.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6335..7183
                     /locus_tag="ACF3UF_002217"
     CDS             6335..7183
                     /locus_tag="ACF3UF_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3672298.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7197..8669
                     /locus_tag="ACF3UF_002218"
     CDS             7197..8669
                     /locus_tag="ACF3UF_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFD3672299.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQKRIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8686..9558
                     /gene="scrK"
                     /locus_tag="ACF3UF_002219"
     CDS             8686..9558
                     /gene="scrK"
                     /locus_tag="ACF3UF_002219"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFD3672300.1"
                     /translation="MIYGSIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(9793..11174)
                     /locus_tag="ACF3UF_002220"
                     /pseudo
     CDS             complement(9793..11174)
                     /locus_tag="ACF3UF_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11636..11959
                     /locus_tag="ACF3UF_002221"
     CDS             11636..11959
                     /locus_tag="ACF3UF_002221"
                     /inference="COORDINATES: protein motif:HMM:NF015824.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HFD3672301.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTHFGSVAKFSK
                     KSILV"
     gene            11991..>12122
                     /locus_tag="ACF3UF_002222"
     CDS             11991..>12122
                     /locus_tag="ACF3UF_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFD3672302.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVSH
                     "
BASE COUNT         3763 a         2068 c         2440 g         3851 t
ORIGIN      
        1 ttaaaaagaa aagtgacaga taggaataaa aacttattaa atgtagttat gatctgttat
       61 atttcatttc taatactagg tcttccacaa gcagtgtttc ctgaaatgtt ttctggagac
      121 tggggtattg tcagctattc tatattaaca ttgattgcta tggttttagg tacttcattt
      181 tataatgctt ttgtaagtaa gcatgttgag gaatatgaag tattaatgta cttaaaagag
      241 aaaaaaacaa gtaattaata tgagaacacc acgcatagtt tttattttga gatattctag
      301 aatgaaacac attaagaacg aaagcaaagc aaaagacgcc agaacttcta ctaccttcta
      361 agttttttca tatttgtttg ttatgctata catagatctg cataattaga cttgcgctgc
      421 ccgttattga agtttcaggc agcgctcttt ttgggggatc gataatggaa gaagaaaaaa
      481 tatttgagaa acgctggcag ctagcatcaa gtgaacaaag agcaagatac aataatttga
      541 tcacctccta ccccactgtt gactagacat ataaggaaaa gaaatactta ctttggctgt
      601 gccagttaga tatagatacc tttgagatcc tagataaaat taaacagaat tgatcagaaa
      661 caagcgaagc cttctctcgg ttcgcttgtt ttgctattta ttagttggct cagggcaact
      721 ctaagctcgt ttgaaagaaa accgatggat aatccccttg tttgtaccac tttagaatac
      781 atggatgtac gtattgccat tgactcctat tagttactga aaaaaaattt aaacaagttg
      841 agtattgcag ataaatagct ccagtgaggt gaataactgc tccactcaag gcaatagata
      901 gctccatcca gggcaacaaa ctgctccact ttcatattta atagatgaat aaccttctgt
      961 ataatagaaa ggcatacctt tcggtatgac aacttataca gaatgttatt ttattggttc
     1021 actatcgaaa aattttggag ctttattttt ccggtatttc tcaacgaacg attagtttaa
     1081 ctgtgggaag ctccagacat acgattcgag aagttacttc tcgagcagac aggaaggggg
     1141 tgactgaact aaccgctgat atgagcgata cttggctgta ggaatatctt tttccggaaa
     1201 aacaaacaac agcacgaggt taccttcctg tagactggga atatgttcat aaagaactaa
     1261 tgaaaaagaa tatgacattg aaactccttc atagagaata tggggtacat ggaacataga
     1321 aacgaaaatg cacggtagaa aagcgaatga atatagtata aattctacaa atcattcgct
     1381 ttctttattt tatatatggt tggtcgagag agaccatttt ctttggcaat ttctgcaact
     1441 ggaactcctt gatttaacat gtccaccaca gttttaaaga ctaatcgttt ttgcggatct
     1501 gttgagttct cagaatattc aattggtcgc cccttatatc gaccagcttt tttggccaat
     1561 aatactcctt gccgctgacg ttcacggatt ttctcacgtt cgttttgtgc aatataactt
     1621 agcaatgata aaaacatatc gaacatagca gtatctagga gttcatttcc agtattaaaa
     1681 tctaaaaact gtgcatctag tatttttaat gctacttttt tctgtttcat aaaggtaact
     1741 gtatttttta tgtcttcata atctctgcct aggcgatcca gtgatgcaac aatgacacaa
     1801 tcaccttctc ggatataatt tagtaatttt tgaaactcag gtcgctggat atctttacca
     1861 ctggcttttt cttggaataa tttatcaatg ttaaggtctt ccatcattgc caattgtcga
     1921 tctaaatttt gatcttgtga agacactcta atatatccaa tttttgccat aaaaactcct
     1981 tttaaaaaat gatataattt acatgtaaaa tttacttgta gttttactgt tatcatagca
     2041 tttttaaaaa taaattttaa gtctacttat aatttacttt ggaggttttg aatgaatgaa
     2101 attaagcgca ataaaaattc ttttggtgtt tatttaggag agcctagctc ggaacagtta
     2161 aataaaggtg aagctcgtca tgctctatgt cgaaatatat tttatggtag aaaaggcaaa
     2221 ctttatcaaa cttattacga cggtatggag gaacagctca acgcattagg attagtaact
     2281 aatgctatca tatattggaa ttcactatat ttagaaaaag tctttgaaca aattaaaacg
     2341 gaagggttcg actgttccga agaagtgtta cgcaagcaat ttccattaat tagtgatcac
     2401 attaattttg ttggcaaata tagtttccgc tatgaaaaag aattatcgaa tggaatacta
     2461 cgtccgttaa atatagagaa ttattgagaa tgttcgtctt ttggttccta ccgtgcattt
     2521 tcgcacggat gttccagata ctatttttga atgtataaaa ttgaaaacac aagaatacta
     2581 ataaatcaac gattcttgtg tttttaattt ttcactaccg tgcattttcg tttctatgtt
     2641 ccatgtaccc caatcttgaa aaattaatta aagacttaga taaagccatt gacgacttag
     2701 tcgtggtgct accggagtat caatgtttaa ccagtatccc aggtattggt cctgtttagg
     2761 ctgctggaat actcgctgaa attggtccaa ttgaacgttt ttctgatgaa ataaaattga
     2821 caaagtatgc cggcctatat tggcgacaga gtcaatccgg taaatctgaa tacgaaaatt
     2881 tttttacgaa aagcttcacg tctaatatct attttaaaat aaaaatattc ctgctaattt
     2941 ggaatcgttt ccttcttttg gtataataat acctgaaatt cttttgagag gagttgttcg
     3001 tgaagtgaaa actactatga aggatgttgc tgcgttagca ggagttggtg tgggtacggt
     3061 atctagagta ataaatggag taaaggtgaa agaggttacc aaagaaaaag taatggctgc
     3121 aattagtgag cttaattatg agcctgatga atatgccaga ggtatgaaaa cgaatagtag
     3181 caatacaata gctcttattt tacctacgat ttggcatccc ttcttttccg agtttgccta
     3241 ctatgtagag gaagctctca gccaaaaaaa ttataagctt tttttgtgta atgcgaacgg
     3301 cagtgcggaa aaagaaaaag aatatatcca aatggtcaag cagagtaaag tagacggaat
     3361 tataggtatt acctattcag acattgataa atatgtatca tcaaatttac catttgtcag
     3421 tatagaccgc catttttcgg aacaggtttc ttatgtaacg gcagataatt atttaggtgg
     3481 gcaaattgcc gctcaagaac tacttactcg taactgtaaa aacttgtgct atgttggggg
     3541 tgtttcacct taccctaacg aaacaaacaa tcgtaaagct ggtttttaca atatttgtga
     3601 ggaaaataaa atagctgtga aggtattgga tatgcctgaa ccaattagca atttagagga
     3661 acaattgctc gctttttttt cggataatcc tgaaattgat agcattttta ccatcaatga
     3721 tttcatggct ttggatgtga taaaagccca aaaaaaacta gggaaggaag cacctaagga
     3781 ttttcaaatt attggttttg atggagtcaa gctatcgttg caaaaagact atttactatc
     3841 aacgattgta cagccgatag aggaaatggc caaggtttca gtagaaacac tcatggcgat
     3901 gattttaaat gaagaaccgc ctaagcgtgt ggtagtaccg gttttctttc acgctggaga
     3961 gacgactaaa gagtaaaaaa ccggtttata acgatttttt tgagataggt tgacagaaag
     4021 tgatttcaat gatatcttaa aaccaattaa ttggaaacgt taccaattaa ttgaaaaata
     4081 aaacggaaac gtttcaaaaa ataggaggaa catcgatgaa aaagagaatg ttagcaattg
     4141 cagcaatttt agcattaaca gctggaggac ttgcaggatg tggcagtaag gagaaaagtt
     4201 caggtagcag tgatccagga gaaattaaga tttgggttca gttttctgat gaaacgcctg
     4261 aaggaaaagc ttgggcagag attgtgaaca attttaatga tgaatacgag ggtgaatata
     4321 aagctgttac tgagtatatt cctcgtagcg gaagcggcgg tggatatgag gataaagtaa
     4381 atgctgcaat tacaaccaat acccttcctg atgttattac gttagatgga ccgaatactg
     4441 cagcttatgc tcattcagga gtcattgctc cattagatga ttatttgaaa gatgcggaca
     4501 tggatgatgt attagacagc attattcagc aaggaaccta cgatggcaaa atgtatgcgt
     4561 ttggtttctc agagtccagt gtgggtgtct attacaataa gtcgctgttc aaagatgctg
     4621 gaattacaga agatcaattg ccgacgttag aagatccttg gacttggacg gaatttcaag
     4681 caatttgcca aaagctgact gataaataca aaacgcctgc aattgatatg caaatggcgt
     4741 cgggagacga aatgctgacc tacgcatata caccatttat atggtcgaat ggcggcgatg
     4801 tcgttaatgc tgatggaacc aaagccgaag actattttaa cggtaaaaaa tccgttgaag
     4861 cgttggaatt tattcaagaa ttggttgaaa aaggttacac cacaatcagt cctattgaaa
     4921 aaggatttga aactggcaaa tatgccatga tgctgagcgg ttcttggaca atggcagatt
     4981 tagaggaaaa ctatcaagag attgattatg gtattttgcc ttaccccgtt tcagatgcaa
     5041 ctggggagtt agtttcacca accggaagct ggcagttagc aatgactgag aaaacagaga
     5101 aaaaggatgc ttctgcggcc tttattaagt ttgcaaccag tacagaatct agtcgtatta
     5161 tgagtttagg gaacagtgtt ctacctatca gaaattcaac agttgattta attaaagatg
     5221 aagtgtcgga aggaatgcag gtattaatta agcaaaacca actttctgga catgcccgcc
     5281 cagtggttgt agcttatccg caagtatcta gagcattcca acaagcagtt caagatatta
     5341 gctacttcga ggaaaaccca gatgtacaaa aagtagcaga tagtcgcgct gctgaaatgc
     5401 aacaggcaat tgatacttca ctaaaataga agtttctaaa gggggccaat caagtgttaa
     5461 aaaaaccgac aatgaaagac aatttgatag gttacggctt tctagcgcca gctttgctgc
     5521 tgctgacgat ttttctgatc atacccgtaa tcatggtaat ttattatgcc tttactgatt
     5581 attatttgtt aacgccagat gctagacaat ttatcggctt agaaaatttt aagcgactgt
     5641 tcgctgatcc aatttttgta aaaagtattt ggaacacggc taaatttgtt gtttggatta
     5701 ttccggtcca aataggggca gctttaggaa tggcacttat tatcaacaaa aatcgtaaag
     5761 gaaatatctt ttttaaagta gccttttttg cgccagtcgt gatgtcctta gtcgttattt
     5821 cgattttatg gttgtacttg ttaaatccta atgaaggtct ggttaatacg ctatttgcaa
     5881 agattggaat tgcttcgcag ccttttttga ctagtcccaa acaagcaatg tatacgcttg
     5941 ttttcgtatc ggcatggcaa ggtgcaggat atcagatgct gctgttttta gggggaatgc
     6001 aaaatattcc gcaagacgtt tatgaggcag ccgaaattga tggtttttct aagtttcagc
     6061 aatttcgcta tatcaccatg ccattattaa agcccacggc gatttttatt ttacttacca
     6121 cattgatttc ggcctttaaa ctaatcattc agccaatggt aatgactcaa ggtggaccaa
     6181 tgaattctac tatgacaatg gtttattaca tttaccaaac tggatttaca gaccgtatgg
     6241 taggctactc cagctccatt gcgttaatct ttaccactat gattggttta attacaattg
     6301 ctcaaagaaa attggtaaag gaggatgatc cagcatgacc aagaaatttg gaccgctaat
     6361 gatcgtagaa tattgtttgc tgttcctttt agcggcatta ttcattttcc cgatgctgtg
     6421 gatggtagtt tcctctatga agcctgaagc agatgtctat caaaatttag cttccttcaa
     6481 agctttttta cctagtttga atccagctaa ttggtttaaa acttatcaag aggttatttc
     6541 ccggttcagt gtgggaactt atttattaaa cagtattttt tatggtttaa cctttgcctg
     6601 tgggtcaatc attgtaaact ctttggcggg ttttgccttt gcgaaggtta atttttcagg
     6661 caagaaaatt atctttggag ctttgttagc tctgctgatt gtcccgatgg agacggtttt
     6721 aattccgcaa tttaccatcg ttaattcact aggcttagtg aatactcgct tggcagtgat
     6781 tttaccagcg atggccagcg cgtttaatat ctatctgttt agaaatttct ttatcgcgat
     6841 tccagaagaa atcattgaat cagcgaaatt agatggtgca aatattgtta aaattttctt
     6901 tcacatcatg ctgccaatgt ctaaaccagc catagccaca gtaggtgtct tatcctttat
     6961 ctccagctgg aatgattata tttggccgtt aatggtctta actgacagca gcaaattttc
     7021 aatgcaagtg gcaattacta cgatcaatac tacacagcca gtttatatca atcaagtgat
     7081 ggctgtttta accattgcaa cgattccact gattattgtt tatatcgttg cacaaaaata
     7141 tattctgcag ggacttggcg gttctggaac gggtataaaa taggagtgaa tagtgaatgt
     7201 tgcaaaaact tttaaaggcc aatgagttta ttgagaaaaa tgctcaaaca gtcaatcaag
     7261 aataccggaa taaatttcat ttgatggctc cgattggctg gatgaatgat ccaaatggtt
     7321 ttgtttatta tcaagaggag tatcacttgt tttatcaata ttatccttac gacagcatct
     7381 ggggaccaat gcattggggc catgctaaaa gcaaggatct aattcactgg gagcatttgc
     7441 cagtagcact ggcaccaggt gaaagctatg acaaggaagg ctgtttttcc ggcagtgcca
     7501 tagaaaagga tggcaagctg tatttgattt atacaggaca caatgttgtg gaagggcaag
     7561 ttcgacaagt tcagtgtttg gcagtttcag aagatggcat tcactttgaa aaatatgccg
     7621 gaaatccaat catcgcagaa gatcacttag cttctgttgc aacgaccgaa gatttccgcg
     7681 atcccaaagt gtttcagcga aaagaagact attttactgt agtcgctact aaaactgcag
     7741 atgctcgtgg acaaattgtg atgttccatt ccaaagattt actaacttgg gagttttatt
     7801 ccgtattgct ggagggaact ccagaacaag gcattgtatg ggaatgccca gacttgtttg
     7861 aactagatgg caaagaagtc ttgattcttt ctcctattca aatgactcca caaggcaatg
     7921 cttaccaaaa tacgaactca actgttgctt tcatcggtac tgtcgattgg caaacaggca
     7981 aatttctagt agagaatttt catgaaatcg atggcggttt agatttttat gcaccccaga
     8041 cctgtgaaaa cgaagcaggc caaagaataa tgattgcttg gatgcaaatg tggcagcgta
     8101 aaatacctac gaatgatctg ggccatggtt ggtcaggttc catgaccttg cctagagagc
     8161 tgagggtggc tgataatcaa ttgttgcaac ggccagtttc atcaatttat caagtaattg
     8221 atccgcagaa aaggattgaa tgggcgaaga ctgaagagaa tcgcttctta ctgaaggact
     8281 tagtatatga ccagcactat ttacgcttgg aaatcaattt aaaacaggca acgaaactag
     8341 aacttcacta tgcgaaggga cccgaccata cattactgct taactatgat gttgaacggg
     8401 agtgctttac tgcttccagg gaacacatgc cgtatgattt atcaggagct gaaaaggaag
     8461 tgttgaaaaa gcgcagtgtg acgattcctt tggaaaataa ttgtctaacc atcgaaattt
     8521 tccgtgatac ttcagctatt gagctttttc taaatgatcg tctgactatg agtacaactt
     8581 tttatgagac agaaaaagga caggattttc ttttgctggc agacagtgaa gtaacctttt
     8641 cattggaaag cggcttaatt aatctataga agggagagct cagtgatgat ttatggttca
     8701 atcgaagcag gcggcacaaa atttgtgtgt gccattggcg atgaagaaat gacgatcaag
     8761 gaaagagtga gctttccgac aacgacacct gaggaaacaa tacctttagt cattgacttc
     8821 ttcaaacaat accaagcaga tttagcaggg attgggattg gctcatttgg gcctatcgat
     8881 atccatcgcg attccgccac ttatgggtac attacctcga ccccgaaagt ggcatggcaa
     8941 aattttgatt tcatcggtac catgaaaaaa gaatttccga tcccgatttc ttggacaaca
     9001 gatgtcaatg cggctgccta tggtgagtat gtcttcggca gtggcaaagg attgagcagt
     9061 gtcgtttact atacgatcgg tacgggtgtt ggcggcggtg ccttacaaga agggcgcttt
     9121 atcgaagggt ttagtcatcc agaaatgggg catatgctcg tcgtccctca tccaaaagat
     9181 gactttgctg gcagctgtcc atttcatggc aactgtttag aagggatggc cgctggaccc
     9241 gccatcgaaa aacgcttagg gaaaaaagga caagaggttg cagaagatga tccttattgg
     9301 gaaatcgaag cctcctatat tgctcaatgt gcctacaata caaccttgat gttttctcca
     9361 gatgtgatca tttttggcgg tggtgtgatg aaacaacgcc atatgctgca aaacgtccac
     9421 gacgcatttg caaaattggt caatgggtat gtcgaaacac ctgagttaag caaatatatc
     9481 gtgaccccag cattagaaga caacgctgga acgctcggtt gtttggcatt ggctcgagaa
     9541 gcggtcttac attcataaac gaaaaaaggc tcttcgacat ttagtgttgg tagagaaaga
     9601 tacaactgaa aatttagtca taaccagtta ggcagagtgc ttaactggtt tttgttttac
     9661 ttggaagatc aagccttgaa tgagataaat tcttgctcga aagttatgga aatttcgata
     9721 gccgtaggcc acttgtattg tgcaatagtt ttttacaaaa aaaagggggt gcggatattt
     9781 ttttggacct ttttaacaaa tatatctttg cttcttccga tattgaagag ggcttagccc
     9841 tcctaaagat aacttaattc gttgattatt ataccaatga atataatcat ccaatttgtt
     9901 tataaactga ttgattgttg tattcttcca gtcacgttga taaaacatct cgttttttaa
     9961 tcgtccaaag aaaccttcgc acgctgaatt atctggtgaa taaccctttt tagacataga
    10021 gtgaagcaag ttggctttgt tccaatagtc caactaacaa tagcaccatc gtaacaatcg
    10081 acaagtggtg ataagtagat tttccctgcg ggaattctaa attcagtaat atctgttaac
    10141 catttttcat ttggcttctt tgctttaaaa ttccgattta ataaattggg gtgtgcagga
    10201 gaaatttccc cagcatacga agaatacttt tttcgtctag aaaatttaac aaatagattt
    10261 tcctcagtca tcaatctacg tacaactttt tcagaaagct ttttacccat attttttaaa
    10321 gcttggtgaa ttctacggta accatacgca cagaagttat gattgaaaat cgtgataatt
    10381 aattgacgtt ctttgtaata cttatctggt ttctcaagtg cttgtttttg ataaaaatag
    10441 ctgcttttag gcaactggag ctgttgaaga agctctttca aggtgaactg atttcgtaag
    10501 gcatcaatca atatcgtttt ttcttgattt gatagacaaa gaagattgac gcctttttct
    10561 ttttttagca gttcagccgc tccttcgagt aatgtttttt cgagctgtaa ttggtgtact
    10621 tgtttttgta agtcttctac ttcctttaaa agtagctctt tttgtttttc ctgatttttt
    10681 aaagtcatac gcaatggaaa atcctttcca agaaccgtgt ttttccattg atatagagta
    10741 actctactaa ttccttcaga ttctgctaaa tttttcctat tagtttgcgg tttatagaat
    10801 tttttcaaca cagcttcttt ttgatcttgt gttaacttta ccgcactttt tcggagtttt
    10861 ctagctcctg gtgcaagttc ttcacaccgc tgccgcaagg actctctatt aggataacca
    10921 agcatgcgaa tggttcgtgc ataacattga ccatattcaa aataatgatt caccgctatt
    10981 cgtttttgtt cttcagaata ctttgatttt tttcggtgct cctgatggag ctctccggat
    11041 tccaaatact ctttatacca tttccgtagt gcaccaatcg acggataccc taattctcga
    11101 atggttgcag cataagagca atcgtatttt aaaaataact gaattgccct tacacgctct
    11161 ttgtgggaaa acacacggac attcctccta agtttatttt ttcgtccagg attatgtccg
    11221 cacccccttg ctttctgatg acttattctg gttctttgag tgtcaatgca tagatgtgat
    11281 gtagctagtt agaaaaaaat tttgaatact ctttttttct ttcagactcc tttttaagta
    11341 agattttgaa gtgtgagtta cggggtcaga aacttaaaag tttttgatcc tttattttca
    11401 agtctgattt ggcagctttt cggcagctca tttatttatg gtcagaaata gatgctgaaa
    11461 ttttaatcta ttagcaaata gtccagaacg tatgaagagg agtcggatat catttgtcat
    11521 taacaccata aatatttata aaattcgtgt tcacctacaa ttaaatttaa tatataatat
    11581 tcgttgtaag ggcttataat tttttgttaa tgaacaagat aggaagaaac atttaatgga
    11641 cagttttcag agattgtcac tagtaaatca atttgagtta ttggctaaat ttgaggacca
    11701 aaacagatct tattatgaaa gaaaaatcga aatattgaga gaaggttacg agtatcatta
    11761 tgatgatgaa atttggagtg atctttctga gccatttccg aaagaagatt ctcgatttgt
    11821 attagatgta ttgaacatgt atcgagatat caattttagt aaatcaaagc taaacttaga
    11881 tgaaaaccaa attactaatt catactatac tcatttcggt tctgttgcaa agttttccaa
    11941 aaaatctatt ttagtgtaaa attgagaaaa aagacagaga gggcagagta atgaatcatt
    12001 ttaaaggcaa acaattcaaa aaagacgtca ttattgtcgc tgttggttac tacctgcgtt
    12061 acaatctaag ctatcgtgaa gttcaggaat tgttatatga tcgtggcatt aacgtttctc
    12121 at
//
LOCUS       DAXLPY010000073        11583 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.073, whole genome shotgun sequence.
ACCESSION   DAXLPY010000073 DAXLPY010000000
VERSION     DAXLPY010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.073"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(865..1251)
                     /locus_tag="ACF3UF_002223"
     CDS             complement(865..1251)
                     /locus_tag="ACF3UF_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672303.1"
                     /translation="MIDKQITNILQSYKKQQIFKIEDFLLSEIDEDNLQETIDFVVSD
                     DVSKKINFSDELYDGNEYEGVFLEGNQYLLSSSEGKVMIIDMLSEAHGVNIKDTRVQF
                     DEEKFIKLITNKKEILNWIKNYKVDK"
     gene            complement(1268..2335)
                     /locus_tag="ACF3UF_002224"
     CDS             complement(1268..2335)
                     /locus_tag="ACF3UF_002224"
                     /inference="COORDINATES: protein motif:HMM:NF013630.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3672304.1"
                     /translation="MAKPSTPATYKVKAGDSVWGICEKYGLSISKFVQWNKIKNNTIH
                     PGQKLTVKQPVSSGKPTTKVPASTNPVTHKVSYGESLWLISSKYGVTVDELRKQNGIK
                     GDLIHPGQVLVVKKGMTTSHSTPVGKSGTSYTVKAGDSVWLIANRYGVSMDDLVKWNK
                     IKNYTIHPGQVLTIQTIVSTPAKPAITTTPKVKAKPAITTTPKAESKSGVTTTPKVDE
                     KPVITTIPKVKEQPVVTTVPKTESEVLVEKASGDGSRLDINIKNFEIKNKHLNSSTAK
                     RARKFNVSSAEEANKIVQDALKNGKLVEAIPNGVGSQGQNSFSSIIDTGKVIGTKGET
                     HIKIVYDELKNVWTTYPVPKP"
     gene            complement(2857..3369)
                     /locus_tag="ACF3UF_002225"
     CDS             complement(2857..3369)
                     /locus_tag="ACF3UF_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016617327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672305.1"
                     /translation="MKIKSYEDKLVKDDIEVDYYVPITVSFPENDDKYNLGEFYYYRF
                     VNEYESFVEIKINSVTQKIVEVVFTSINDIEDSNLFIGEYAEKNPVIQTDIFDENSII
                     TKESGFKISREHKKLCFKLDKEKMDSVVKMSNHVSLFLNEDSEIIGLEFSSFSDNEWA
                     ELNESIKSTT"
     gene            complement(3388..6351)
                     /locus_tag="ACF3UF_002226"
     CDS             complement(3388..6351)
                     /locus_tag="ACF3UF_002226"
                     /inference="COORDINATES: protein motif:HMM:NF013630.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3672306.1"
                     /translation="MLKKVLRFGVCISIWLVTSSTFVPSMIAVADSVAIQETIASDSE
                     GEEKLTERSDDASDGQTEKVEVQKTETTQTTVSSSSDESSDLTQSSEETAPEEVDEST
                     EESSDPQEQTISHEEETKEAVDSSTIDFEGTRSSESFGKHTSPSIDKPNEKIAEPVSS
                     NEGAVVSRRSRRDLSAVSSNHPEEEPVVAFDEKAFDAAIDQYIDHATEEELGLVINSS
                     NEKELADALEYLLLNQLDESFGVEELDELKKFLTADEIERLENESSLETFEQLLTQYY
                     NDREQKLEEGAAFSDFFLASTDEEIDRMLEVKDEQALEQVISEISASRNSQTSGKRNK
                     RFLVIPLLVKGAMLVIGAGVAAYSSHQFYKTMEAQRAEKKRMVERWRYHEQQAQKRHQ
                     AAQQARAKAVARAKLQAAARAKAQATQRARAQAAAKARKQAQNWAKQQAAARARAQAA
                     ASARRKSNASYVPPVTRPKPVIKAQPKVPAKPVAKPVTKPTSPAKPKPTTTPKNTMHQ
                     VRAGESVWSISHKYGISMNDFIKWNKIKNNLIHPGQQVIVKQPASTSKPVSKPATKSS
                     TPATYKVKAGDSVWGICEKYGLSVSKFVQWNKIKNNTIHPGQVMHLQEPKPASKPAPK
                     TSPTTNTTYTVKAGDSVWLIANMHGISMNDLVKWNKIKNNTIHPGQKLTVKQPVSSGK
                     TTTKVPASTNPVTHKVSYGEPLWLISSKYGVTVDELRKQNGIKGDLIHPGQVLVVKKG
                     MTTSHSTPAGKSGTSYTVKAGDSVWLIANRYDVSMDDLVKWNKIKNYTIHPGQVLTIQ
                     TIVSTPAKPAITTTPKVESKPAITTTPKVESKPGVTTTPKVDEKPVITTLPKVKEQPV
                     VTTVPKTESEVLVEKASGSTGTVWDDIKGTQPPREGTTIPKSFEIIVNGEKLWVNPNG
                     TKHMVEYSTRNLSHGQKLTEQQLLRSFQGAVEQATSTGIKFETKIIIDNWELIFSPAR
                     EAGQLPVIKHAVYLP"
     gene            complement(6597..7064)
                     /locus_tag="ACF3UF_002227"
     CDS             complement(6597..7064)
                     /locus_tag="ACF3UF_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672307.1"
                     /translation="MKKSLIVLIVGLSIFGSVLFIGNSLFSNKDVTEQSPASTTEEVS
                     PELLLETDVLDTKKPETIPSENELYQGDLSFEYADPEKPYVLTIRFIDKANHEYVGPD
                     KKPLKREKELILGKAKGVVHVVVKANRSMLTHIQKLKDIQVSMTLNERNEKTE"
     gene            complement(7086..7238)
                     /locus_tag="ACF3UF_002228"
     CDS             complement(7086..7238)
                     /locus_tag="ACF3UF_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672308.1"
                     /translation="MKKKGIPYSPKPRNAFERGLFKYFEGERDQEEKEKNQKKKSSQE
                     KENIEK"
     gene            7739..8080
                     /locus_tag="ACF3UF_002229"
     CDS             7739..8080
                     /locus_tag="ACF3UF_002229"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672309.1"
                     /translation="MKANTPYKVGDIFYSSWGYEQTNVTFWQIIKLTKKTAWFRPIKK
                     QTVKNYTSMSGETMPIPNEFIDYPLARTKDSIVRKRINPALYPNELYGNRSWDTFYRY
                     DNQPVYESSYY"
     gene            8273..8566
                     /locus_tag="ACF3UF_002230"
     CDS             8273..8566
                     /locus_tag="ACF3UF_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672310.1"
                     /translation="MLRTNAIPIVDSYDRNTNNYLGSFEQTDENILNYVAGLSPFESV
                     RLVEHTTDTLILTTIGYFFDQVSDQQWLQQILPKLIAKQTGKSTIEAVKIFFY"
     gene            8622..9170
                     /locus_tag="ACF3UF_002231"
     CDS             8622..9170
                     /locus_tag="ACF3UF_002231"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672311.1"
                     /translation="MSILQPFGEPIERTEFIQHYMKLFVQVIKHTHQIDEFYSKEIEY
                     LLAEKQKIALLYDYFVEMYDRAPDYFYLSDTLTTNFLAKEHLFASHTKNLMCVEHFVN
                     TYLHLLKIQKICTFEAFQTDYLFILDREAYHAKLAFEKQNQAIEGYPELRIQNNSFLQ
                     QRLLKQLINGFHQRNKAYQKDQ"
     gene            complement(9567..9764)
                     /locus_tag="ACF3UF_002232"
     CDS             complement(9567..9764)
                     /locus_tag="ACF3UF_002232"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672312.1"
                     /translation="MGQYFLTGVWYVLKLVIILGIAYICFRILLSGEGMPTPKDFIIS
                     VLNFVADQIQVIIHWAQQRFG"
     gene            complement(10269..11444)
                     /locus_tag="ACF3UF_002233"
     CDS             complement(10269..11444)
                     /locus_tag="ACF3UF_002233"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3672313.1"
                     /translation="MDGTQLKQMRLSRNLTQKLVADTLGWPQSFLSMIENDQRSCSKE
                     QEEALCEFYANFSSFTSLEIKFDYVRVRVPTNDTKTVVEEILGMDFNSFFYAETRLYG
                     YIEMYQKGMIRVLNSKKGDDKGVLIELSGQGCRNYESVLDERNDSWYQFFTRCVSFNG
                     VSRRIDIAVDDFEELFSLHEFAQKLNRGEFDSKFRTWRFQEEKQLLDNLSSGLSVYLG
                     SSQSLMYFCFYQKNYEIAKKQKLPLEEVEVKNRYEIRLRDAKAVSFIEQYLNKVDFSD
                     LTMGILANQLIMFEGEKNTNVWKPWGKLIQNVGKVNLTVTPEKPNYNRKLMYLKTQPA
                     RTMKIVKTVDEILGLNRFGEILEETELREQDEKIVEDEVRAVYEYIQENPDAIHYLL"
BASE COUNT         3398 a         2287 c         1733 g         4165 t
ORIGIN      
        1 aaaatactac aactcagata ttttttacaa cgatttacag aaaaataacc tctttaaata
       61 taaaaagtat gggttactga ttacttataa atctttacgg tctagtttcg caacaattcc
      121 tttctttcta aaaaatatac tcacattttt tctttcttgg acttcttttt tgattcttct
      181 cttttaactc ttgccccttt tctccttcaa aatatttatg cttcctcttt caaaaacgtt
      241 tttaggtttt ggacgataag gagtgacttt ttttcatata aacacctcat tcaactgttc
      301 gatccatttt atatcatcac attataaaaa taacaaatat attaaatttt tttatcaaaa
      361 tcatcttaac cttttggaag attacagtac gctttctttt tattcccaaa ctttttttgt
      421 tgctcacttt cgtatagcca atctaagcga tcatcgacga cggtgctttt acaacgaatg
      481 gttagttttg ggcgctgact tatctactgt tttatagtag attatcttct gagaattctc
      541 atattaaact tttgtatacc tctaaagtgg atataaagct ttcaactgta cctcaagaac
      601 gcctcgaaag cttcaacaac tatttcaaca ataaattgtc tttctttgat taaaatttat
      661 atatcattca aataattaac tattaaaatt aagcgataaa atagaaaaag aaacgataca
      721 actaaatcgt ttctttttca acttcagctt atactattct atacatagat aactttttat
      781 tagcaacttg attagtgagt gtatgcttac tattcaaggc tttgctattc gacgccaatc
      841 gaatagtaaa gtgccttttt tattttattt atccacttta taatttttaa tccaattaag
      901 aatttctttt ttgttcgtga ttagtttgat aaatttttct tcatcaaatt gaactcgagt
      961 atcttttata ttaacaccat gagcctcact taacatatca attatcatta cttttccttc
     1021 tgagctagat agtaaatatt gattaccttc taaaaataca ccttcgtact cgttcccatc
     1081 atataattca tcactaaagt taattttctt actaacatca tcagaaacta caaaatctat
     1141 tgtttcttgt aaattatctt catcaatttc tgaaagtaaa aagtcctcta ttttaaatat
     1201 ttgttgtttt ttatacgatt gcaaaatatt cgttatttgt ttatcaatca ctttgcttac
     1261 ctcctattta aggttttggg acaggatagg tagtccacac attttttaat tcatcataaa
     1321 ctatttttat atgtgtttcc cctttggttc caataacttt ccctgtatca ataatactag
     1381 aaaaagaatt ttgtccttgg ctccctactc catttggtat agcttctaca agttttccat
     1441 tttttaatgc gtcttgaact attttattag cttcttcggc tgaagaaaca ttaaactttc
     1501 tagcccgttt agcagttgaa ctattcaaat gtttattctt gatttcaaaa tttttaatat
     1561 taatatccaa tctacttcca tccccactgg ctttctcaac caatacttct gattcagtct
     1621 taggaacggt tgtgaccaca ggttgttctt ttactttcgg tattgttgta attactggtt
     1681 tctcgtccac ttttggtgtg gtagtcactc cagattttga ttccgctttt ggtgtcgtgg
     1741 taatcgccgg ttttgctttt acttttggtg ttgtcgtgat cgcaggtttt gctggtgtag
     1801 aaacaattgt ttgaatcgtt aagacttgac ccggatggat cgtataattt ttgatcttgt
     1861 tccatttcac tagatcatcc atgctcacgc cgtatcgatt agcgatcaac caaacagaat
     1921 cccctgcttt tacggtatag ctggttccgc tttttcctac aggagttgaa tgactcgtgg
     1981 tcataccttt tttgacgact aatacttggc cggggtgaat caaatcacct ttgatgccat
     2041 tctgtttgcg taattcatcg acggtcacac catatttact actaatcagc cataaagatt
     2101 caccataaga gactttgtgg gtgactggat ttgtagaagc gggtactttt gtcgttggtt
     2161 tccctgatga aacaggctgt ttgactgtca acttttggcc aggatggatc gtattattct
     2221 tgatcttatt ccattggaca aattttgaaa tggataaccc atacttctca caaatccccc
     2281 aaactgagtc tcctgctttt actttgtacg tagctggcgt acttggtttt gccactggtt
     2341 tggacgttgg ttttatagta gattatcttc tggaaattct caaattaacc ttttacatgc
     2401 ctctaaagtg gatataaaat tttcaactga agaagcaaag gtcactaata gtaaatatga
     2461 acactatttt tgaatctgga aaagagaaaa ttaatatgac aaatgactaa atagaagttg
     2521 tgaaggtact tgttataaaa caatttctaa aaggagcgga aggcaatgag aaaaatgatt
     2581 cttctgatcc gtaaaacact ataaagaaag tcaatagatc attagtctct cctaatattg
     2641 ctattgactt tctttattgg gcatgtgctt ttgatagtgc ccgaggaact cacaaaatac
     2701 ctagtacctt ggattatccc tcgaaccttt tcagcataac atgcccaccg tttattttag
     2761 catttgaatt tgttctttca aaattctttt gtttcatcct cagaatctag caaaatagct
     2821 gttgaaaatc ctatcttctt ctcatttaaa attaaatcaa gtggtagatt ttatactttc
     2881 attgagttct gcccattcat tatctgaaaa gctagaaaac tctaaaccaa taatctcact
     2941 gtcttcattt agaaataaag atacatgatt agacatcttt acaacagaat ccatcttttc
     3001 tttatctaat ttaaaacata attttttgtg ttctctagat attttaaacc cagattcttt
     3061 agttataatc gaattttcat caaaaatatc tgtttggatc actggatttt tttctgcata
     3121 ctctccaata aataaattgg aatcttcaat atcattgatg gatgtgaata ctacttctac
     3181 aattttctgt gtaacagaat tgattttaat ctcaacaaat gattcatatt cattaacgaa
     3241 tctataataa taaaattctc ctaggttata cttatcatca ttttctggaa atgatactgt
     3301 gattgggaca taatagtcaa cttctatatc atctttgact aatttatcct cataactttt
     3361 aattttcata atttgctcct ttcatagtta tggtagatat acagcatgtt taataactgg
     3421 taattgtcct gcttctctag ctggactaaa tattaattcc caattatcta ttattatttt
     3481 agtttcaaat tttatccctg tagaagtagc ttgttctaca gcaccttgaa aactccttaa
     3541 caattgttgt tcggtaagtt tttgtccatg agatagattt cgagttgaat attctaccat
     3601 gtgcttggtt ccatttggat ttacccacaa cttttcccca ttaacaatta tttcaaacga
     3661 tttaggaata gtagttcctt ctcttggagg ttgtgtacct ttaatatcat cccagactgt
     3721 acctgtagac ccactggctt tctcaactaa tacttctgat tcagtcttag gaacggttgt
     3781 gaccacaggt tgttctttta ctttcggtaa tgttgtaatt actggtttct cgtccacttt
     3841 tggtgtggta gtcactccag gtttggattc cacttttggt gtcgtggtaa tcgctggttt
     3901 ggattctact tttggtgttg tcgtaatcgc aggttttgct ggtgtagaaa caattgtttg
     3961 gatcgttaag acttgacccg gatggatcgt ataatttttg atcttgttcc atttcactag
     4021 atcatccatg ctcacgtcgt atcgattggc gatcaaccaa acagaatccc ctgcttttac
     4081 ggtatagctg gttccgcttt ttcctgcagg agttgaatga ctcgtggtca tacctttttt
     4141 gacgactaat acttggccgg ggtgaatcaa atcacctttg atgccattct gtttgcgtaa
     4201 ttcatcgacg gtcacaccat atttactact aatcagccat aaaggttcac cataagagac
     4261 tttgtgggtg actggatttg tagaggcggg tacttttgtc gttgttttcc ctgatgaaac
     4321 aggctgtttg actgtcaact tttggcccgg atggatcgta ttattcttga tcttattcca
     4381 cttcaccaga tcattcatac tgatcccatg catattagcg atcaaccaga ccgaatctcc
     4441 tgcttttacc gtatacgtcg tattagtcgt aggagaagtt tttggtgctg gttttgatgc
     4501 cggtttcggt tcttgtaaat gcatcacttg tcctggatga atggtattat ttttgatctt
     4561 attccattgg acaaattttg aaacggataa cccatacttc tcacagatcc cccaaaccga
     4621 atcccctgct tttactttgt aagtggctgg cgtacttgat tttgtcgcag gtttggacac
     4681 tggctttgat gtacttgctg gttgtttgac gatgacttgc tggccaggat ggatcagatt
     4741 atttttgatt ttgttccatt tgatgaagtc attcatactg atgccatact tatgcgaaat
     4801 agaccaaaca gattctcctg cacgtacttg atgcatcgta tttttggggg tcgtcgttgg
     4861 cttcggtttc gctggagaag ttggtttcgt tactggtttg gctactggtt ttgcaggtac
     4921 tttgggttgg gctttgatta ctggtttcgg acgagttacc ggaggaacat aggacgcatt
     4981 tgactttctt cgtgcacttg cggccgcctg tgcacgagct cgagcggcgg cttgttgttt
     5041 agcccaattt tgtgcttgtt ttctcgcttt tgctgcggct tgggcacgag ctcgttgtgt
     5101 ggcttgcgct tttgcacggg ctgctgcttg taatttggca cgggcaacgg ctttggcgcg
     5161 ggcttgttgt gcggcttgat gccgcttttg tgcttgttgt tcatggtaac gccagcgttc
     5221 gaccattcgt ttcttttccg cacgttgtgc ttccatcgtc ttatagaact gatggcttga
     5281 ataagcagct acccctgccc cgattaccaa catcgctcct ttgacaagca atggaatgac
     5341 taagaagcgc ttgtttcgct ttccacttgt ttgactattc cgagaagcac tgatttcaga
     5401 aatcacttgt tccaatgctt gttcatcttt tacctctaac atccgatcga tttcctcatc
     5461 ggtacttgct agaaagaagt cactaaatgc tgctccttct tccaatttct gttctcgatc
     5521 attatagtat tgcgtaagca gttgttcaaa tgtctctaac gacgattcat tttccaatcg
     5581 ttcaatctca tctgccgtga ggaacttctt tagttcatcg agttcttcta caccaaagga
     5641 ctcatccaat tgattcaaca agagatattc taaagcatcg gccaattctt tttcattgct
     5701 tgaatttatg actaacccta attcttcttc tgttgcatga tcaatgtatt gatcgattgc
     5761 ggcatcaaag gctttttcat caaaagcgac caccggttcc tcttctgggt gatttgaaga
     5821 aaccgcagaa agatctcggc ggcttcgccg tgaaacaact gctccttcat ttgaagagac
     5881 tggttcggct attttttcgt taggtttatc aatacttgga gaggtatgtt taccgaatga
     5941 ttcagaagat cgtgttcctt caaaatcaat cgttgatgaa tcaactgctt ccttcgtttc
     6001 ttcttcatga gaaatcgttt gttcctgagg atccgaagac tcttcggtag actcatcgac
     6061 ttcttctggc gcagtttctt cgctggactg ggtaagatca cttgattcat ctgaactgct
     6121 cgataccgtc gtttgagtag tttctgtttt ctgtacttca accttttcag tttgtccatc
     6181 tgacgcatcg tccgagcgtt ctgtaagctt ctcttccccc tcgctatcag atgcgatcgt
     6241 ttcttgtatc gccaccgaat cggccactgc aatcatactt ggcacaaaag tggaagatgt
     6301 taccaaccat atacttatac ataccccaaa tcgtaacact tttttcaaca tatttttctt
     6361 cctttcttca tttacaccta attaaaataa cgatcattat catactgaaa attgtagaaa
     6421 caaatttaaa taggtgttta aagaaataat atcatcattt ttaatgatga taaataacag
     6481 ggaagaaaaa aatgaccttt catttttgta atatgatcaa gcaactataa agatggaaca
     6541 aaataaataa accgataaaa gtagaacaga tattcccaaa acatgtctga tttccgtcat
     6601 tccgttttct catttctctc atttaatgtc atggacactt ggatatcttt taacttctga
     6661 atatgggtta acatcgatct attggctttt acaactacgt gtacgacacc tttagctttt
     6721 cctagaatca attctttctc tcttttcaat ggctttttat caggccctac atattcatga
     6781 ttcgctttat ctataaaccg aatcgttagt acatacggct tttccggatc cgcatattca
     6841 aatgaaagat ctccttgata gagctcgttt tccgaaggaa ttgtctcagg tttctttgta
     6901 tcaagaacat ccgtctctaa taatagctct ggagatacct cttccgttgt gctagcaggg
     6961 gattgttccg taacatcttt gttagaaaac aacgagtttc caataaataa aacacttcca
     7021 aatatactta atccaacaat caatactatt aaactttttt tcatacttct ctattttttc
     7081 acctactatt tttctatatt ttctttttct tgactagact tctttttttg attcttctct
     7141 ttttcttcct gatctctttc gccttcaaaa tatttaaata accccctttc aaaagcattt
     7201 ctaggtttcg gagaataagg aatgcctttt ttcttcatac aaacacctct tttaactatt
     7261 tgatctattt tataccacca cattatcaaa ataacaaatg tattaaaagg aatttcttat
     7321 taaaaccatc ttgacctttt gggagatttc agtgcgattt ctttttattc ccatactttt
     7381 ttcgttggtc gctttcgtat acccaatcta agcgatcatc ggcagtagtg cttttacaac
     7441 gaatggtagg acaaaacaag gggcggaaaa acttttttga tcatttcata aaaaactttt
     7501 tcctacagca ttcccttgtt ttctcttacc acacgttgtg acctaaaagc acgccgacga
     7561 acgcttagct atacgaaaat gaccaaccaa aacaaaaaag tgaggtgaat ggaaacaaaa
     7621 agaaattgaa atctcccaaa aggtcacccg cctcggagac aacttgctgc cgaaaatggt
     7681 tggttgattc ggctaagtat caaataaggc aaatcaaata ttattggagg aatagatcat
     7741 gaaagcaaat acaccataca aagtaggaga cattttttat agtagttggg gctatgaaca
     7801 aaccaacgtt actttttggc aaattattaa attaaccaaa aaaacagcat ggtttcgacc
     7861 catcaaaaag caaactgtaa aaaactatac ttctatgagt ggagaaacta tgccaatacc
     7921 aaatgaattt atcgattatc cgcttgcacg aaccaaagac agcattgtta gaaaacgaat
     7981 taatccagcc ttatatccca atgaattata cggtaatcgc agttgggata cattttaccg
     8041 ctatgataat caaccggttt atgaaagcag ttattactaa gagggtattt ccctcttagt
     8101 caacgttaca aaaataaaag gagcaagaac aatgaaacca ataactctat atgaaatctt
     8161 aggtgaagaa cggtctgaca atttaccaac aacgcataaa ttaagagttc ttgcttctaa
     8221 atctatcggt aaaaaatgat aactgagtat ttctaatcaa ggagagattg caatgctaag
     8281 aacaaatgct attcctatcg ttgattctta cgatcggaat accaataact atttaggatc
     8341 ttttgaacaa acagatgaaa atattttgaa ctatgttgct gggttaagtc cttttgaatc
     8401 tgtacgttta gttgaacata caacagatac actcatttta acaacaatcg gctacttctt
     8461 cgatcaggta tctgaccaac aatggttaca acagatttta cctaaactta tcgcaaaaca
     8521 aactggaaaa agcaccatcg aagcagtcaa aatatttttt tactaaatac atgtattcat
     8581 tctcaaggga ttttttccct tgagtgaaag gagaaagaat gatgtccata cttcaaccct
     8641 ttggtgaacc aatcgaacga acagaattca ttcaacacta tatgaaatta tttgttcaag
     8701 ttattaaaca cactcatcaa attgatgaat tttattccaa agaaatagag tatcttctag
     8761 cagaaaagca aaaaattgct ttactttatg actattttgt cgaaatgtat gatcgcgcac
     8821 cagattactt ttatttatct gatacactta ctactaactt tttagctaaa gaacatcttt
     8881 ttgcctcaca cacaaaaaac cttatgtgtg tagaacactt tgtcaatacc tatcttcatc
     8941 tgttaaaaat tcaaaaaatc tgtacatttg aagcatttca aacagattat ctatttattt
     9001 tagatcgtga agcatatcat gcaaaactag catttgaaaa gcaaaatcaa gccattgaag
     9061 gctatccaga attacgcatc caaaacaatt cttttttaca acaacgattg ttgaaacagc
     9121 taataaatgg attccatcaa cgaaataaag cctatcaaaa agatcaataa ctggttcttt
     9181 ttgataggtt ttttccatca aaaacagaaa cttctttttt taattgtttg attacttttt
     9241 tagtcataaa gatcattcaa atttttttaa ataaattatc catatcttct aatattaatg
     9301 gaacatctgc aattattcga tccctattcg taccaaataa ttcaatcgat gaagcatcaa
     9361 agaaagaaac tattttttct aaattactaa atgtagttag ctcttatctt cctcaacatt
     9421 agaagcgctt tgtacattga cacctaattt attagccagc tctttttgtg tagctccctt
     9481 tttctttggc aatctagata acttatactc gaaattttct atcacatagc ccacttctaa
     9541 acattaaatt ttttaaatat atttttttat ccaaaacgtt gctgcgccca atgaattatc
     9601 acttgtattt gatccgccac aaaattcaac acgcttatga taaaatcttt tggcgttggc
     9661 attccttctc ccgataataa aattctaaaa caaatatagg caatacctaa aataatcact
     9721 aatttcaata cataccaaac accggtaaga aaatactgtc ccatttttcc aacatattcc
     9781 tttctttaaa gtgttaataa ccaaataata ctacagacaa tacaaactaa aagaaacagt
     9841 aatttcaaaa aatgccaacc tacagaaaat aaaaatcgaa tcatttcttt tcccctctat
     9901 ttttcatata tagatatagt ttttcttcca atacttgttg taaatctagg atatcttact
     9961 tggcaaatcg tcatatttca tcattgtttt tactgctttt tcgtatatcc acatacttgt
    10021 gttgcatata aataaatctt tgtcaacgaa tattttaacg aatcactaat acggtagctt
    10081 aatacttccc ctatttctac atgtaacatt ttgattgatt gttgataatc taaatattct
    10141 ttaaataact gtagatcatt tccaacacat aggatcgttt cttttattaa tcgttaacaa
    10201 gcaatcatat actctcccca tcattggtct tctgttttaa tcatgtttca cccatcttat
    10261 cgcaagcttt atagcaaata atgaatcgcg tctggatttt cttgtatata ttcataaaca
    10321 gcacgcacct catcttctac aattttttca tcttgttccc gtaattctgt ttcttctaaa
    10381 atttctccaa atcgattcaa tcctaaaatt tcatccacag tttttacaat cttcattgta
    10441 cgagcaggtt gtgtctttaa atacatcaat ttccgattat aatttggctt ttctggtgtc
    10501 actgtcaaat tgacttttcc aacgttctga atcaattttc cccatggttt ccacacattt
    10561 gtgtttttct ctccctcaaa cattattaac tgattggcta aaatccccat cgttaaatct
    10621 gaaaaatcta ctttatttaa gtattgttca ataaaactga ccgcttttgc atcacgtaag
    10681 cgaatttcat aacgattttt tacctcgacc tcttccaacg gaagtttctg cttttttgca
    10741 atttcataat tcttctgata aaaacaaaaa tacatcaaac tttgtgaact acctaaataa
    10801 acagataagc cactacttag attatctaac aactgttttt cttcttgaaa tcgccaggtt
    10861 cgaaattttg aatcaaattc gccacgattt agtttttgtg caaattcatg taaagaaaat
    10921 agttcttcaa aatcatctac cgcaatatca attcttcgag acacaccatt gaaagagaca
    10981 catcgtgtaa agaattgata ccaactatca tttcgttcat ccagtacact ttcataattc
    11041 cgacagcctt gaccagataa ttcgatcaac actcctttat cgtcaccttt tttagaattt
    11101 aatacacgga tcatgccttt ttgatacatt tcaatataac catataagcg ggtttctgca
    11161 taaaaaaaag agttaaaatc cattcccaaa atttcttcca caactgtttt cgtatcattt
    11221 gtcggaactc gtacacggac ataatcaaat ttaatttcta aactcgtaaa acttgaaaaa
    11281 ttcgcataaa attcacaaag tgcttcttct tgttctttcg agcaacttcg ttggtcattt
    11341 tctatcattg ataaaaaaga ttgtggccat cctaatgtat ctgccactaa tttctgtgtc
    11401 aaattccgac ttaaccgcat ttgctttaat tgtgtcccat ccaaatatat ctttcctttc
    11461 ttttgtgata ttttatgtta caaagcgaag aaaaatatca caaaattttt gaagcaaaat
    11521 agtgttatat caatgtttca atcacccatc tttgccaccg aatataaatt ctacccccct
    11581 gtt
//
LOCUS       DAXLPY010000074        11485 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.074, whole genome shotgun sequence.
ACCESSION   DAXLPY010000074 DAXLPY010000000
VERSION     DAXLPY010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.074"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            162..962
                     /locus_tag="ACF3UF_002234"
     CDS             162..962
                     /locus_tag="ACF3UF_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFD3672314.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKVSGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTQNLGMIKEK
                     DEEEMLWKVDGIEYVLDKAEHLVKNAKESLLIQVWHENLTDSLLKTLQQAEKRVDKFV
                     LILFSSSHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESSEELKAKYGEDFEGIRKIY"
     gene            978..1856
                     /locus_tag="ACF3UF_002235"
     CDS             978..1856
                     /locus_tag="ACF3UF_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFD3672315.1"
                     /translation="MIRNILLALIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFITFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGVKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAAFLIFMGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFDEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYVLKWIVILVLLYS
                     AYTMLGSQLKKVSAAN"
     gene            1869..2849
                     /locus_tag="ACF3UF_002236"
     CDS             1869..2849
                     /locus_tag="ACF3UF_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFD3672316.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENLKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFDRASRFAEEMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVNKAKENNLGKLIY"
     gene            3371..3589
                     /locus_tag="ACF3UF_002237"
     CDS             3371..3589
                     /locus_tag="ACF3UF_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672317.1"
                     /translation="MNFFQNVFTDFVGDFKYLIMLAMLGGAAYIAFERKASKAIPLIL
                     VLAVAVWLVGDTSGVFNWILDRMRSWGR"
     gene            3591..3998
                     /locus_tag="ACF3UF_002238"
     CDS             3591..3998
                     /locus_tag="ACF3UF_002238"
                     /inference="COORDINATES: protein motif:HMM:NF024062.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFD3672318.1"
                     /translation="MSEIRNWTKIWYIERVFYKLWDGVALPRPVTQTFAIWFGIGFFG
                     GIFRIFPFVMEHTITRQFFCPWLFAFLMTRKQFQGRKPYNYLASFLLFQCRSKESFHG
                     QWVKPIEKKEIKRGIRCVVRYGGEKDATTKTSA"
     gene            3973..6510
                     /locus_tag="ACF3UF_002239"
     CDS             3973..6510
                     /locus_tag="ACF3UF_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3672319.1"
                     /translation="MRLPKLVPKIPFYYLEDNLVFGEEDRVYAYYEFPMYSYSFVGED
                     QAYQLQQAIMRLIRQSHSSHVRFFFCTNEEKIEKTIKSSKELVRSKGELKTIAYQHLE
                     GVQHILEELHGKYIQNVCWYVGIELVLEEIAPKEAHWLKEFRIAAKDFFHRSNARLFG
                     DFETIPNEKIQRYKRLENLLYNRISKYFRLRKTTPEDMVFLVEHLEGKKEQSLDEVMY
                     RPNSFKEETNTYTYHYDVLNLASAGITEKKNYLILEQGTEKEYITYLSLSRMTRDLVF
                     PFQSEIYYFLQSELDFPIDSWLDVNLLDNRLALAKVRGKKSDLSDIYESGMSVGKDVG
                     NNVREAYQSANELEQKLEDTREDLYVLSLNVRVSGKTYDEMLKRVSDVRNFFDVYSMY
                     LEVPCNVQLLLHFGSYPAGRRVIEDYRQYVGAEFIASLGIGATQQLGDGCGIPIGFNA
                     ETGIPVFIKPWLAAQGIKGTVTNTLAKALIGSLGGGKSLTENLLLFWSVLFGALAFCI
                     DPKSERSNWSEDLPYFAPYLKTVNITSEKENIGLLDPFQLMRRKKDQESLALDVLTYI
                     TGVSIRDEDRFPLLQRAVKTVSDFEGTKGLLLVIQELYAQEAATAQRLAKHIESFKEL
                     SIAGLLFGDGTNQQGLNLDAKCNLALVQDLTLPDSETVPEDYNSSEILSIAIMMSLAT
                     YALDFIKQNRKIYKAVGLDESWAWLNVAQGKILGDKLVREGRSRNAGIDFSTQNTDDL
                     GDEKMRSKIGLKFIFRSNDREEITKALSFCGISVTEENIQRVKNLENGECLFCDIHGN
                     IGILYVYYWFEDLFHAFDTRPPMEETYEEEEYKDEILEKLVEEIEVN"
     gene            6511..8532
                     /locus_tag="ACF3UF_002240"
     CDS             6511..8532
                     /locus_tag="ACF3UF_002240"
                     /inference="COORDINATES: protein motif:HMM:NF046089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFD3672320.1"
                     /translation="MKQWYSKVSFLITRRKLVFISLVIMMGVFFFHPSLVEAAGWIKE
                     TLGGKNAVYDFETYPLDNYNLDFFVDTSWNWLPWKWGEGISNTVIYGIFAVTNILWML
                     NVYLCYFLGFLVQEAFELDFLSELIGSLSHTIQNIAGMNRTGTLSHGLVPFFGGLLIT
                     LAGCSVVYQGIVKQHPTQAIQQAVTFLFTFICCGVFFMNTNTYLEKANGVQKEINSEM
                     LTIAKNLLPEQKEKPDAIKAIRENLFAIQIKQPWLVMQFGDSDIKTVGEERIINLLKE
                     SPYDEGEQRNKLVEEEVTKQKNGHLSVQKVYLRFGMVFLTLIVNIVISMSVLVLIVIL
                     IASQVLFLLFIGFLPVAMIFSLFPNSGSLLGNALQKVFQLLFTKMGILLILTITFSIS
                     HELNHLSKDKGMIWTSFLQVTLWLSVSTRVNELLGWMKIGGVQTRAGDRTGRFLRGMM
                     LGTMGQKMIRGIGENFVGGTAGGVAGQMISKSMSGQRSIASTPLIERVGKKVSAMTEL
                     PATIESRAEQWKRTIQYVPTNAQYKAQKMKYDYFSGRMNESERQTRARNLANERQKNF
                     YEARKDALQLEQQERKQRAMRSMAHQTGKTQVTSGKLQTRKSAMIGRTEQFPTIEKRS
                     NISNIAKNKKLSKQEHPIHERSTNRKIETPVRWTSTSRQNARKGRTKKE"
     gene            8679..9467
                     /locus_tag="ACF3UF_002241"
     CDS             8679..9467
                     /locus_tag="ACF3UF_002241"
                     /inference="COORDINATES: protein motif:HMM:NF024056.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFD3672321.1"
                     /translation="MVFSVCFGVYNNLTSQDTHTIHETKVIDKQLKDMTGIESYVKNF
                     AFLYFTVSLESDQQINRSKAVESYLADGLQMDNEIDKDIETNVKVKNVSIWAIEEHES
                     KKHTFVVMFHVLLEIEKEFKERVYKVEVYRNELSYAIVKLPIVASNVKKATIKVDTRF
                     ETTSISRKEQEELEKFLYTFFRIYPKANAEELKYYGTTLLPIQQPLAFEELSNLQVAK
                     KEGRYEIHCNILYQDQETHLWFTMYYEMSMKQLENGNFRIEAIH"
     gene            9539..10558
                     /locus_tag="ACF3UF_002242"
     CDS             9539..10558
                     /locus_tag="ACF3UF_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002386462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3672322.1"
                     /translation="MSSGESKHMDSAVGVTHTGEYIETLPIFSEIKGRGPITDEHAQA
                     AVGAAVKYQLLPSVILSQLGYESAYGQSQSGRNDTNFFGITWFPGCPYPQGSARGIGG
                     SEGGFYMKFPNLNACYDYYGFMVASQSNFNQCVGNKDPGSCLLILGRGGYAAAGITEG
                     SSYYQGAISIIKSYNLTEYDAFAIKHWNSLPIKKTSLIAGKSKGNAKVLDRIIGRPVN
                     NGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGEDYNWATYGWQVIMNPKPSDLQAGDV
                     VNWQAGGALSPGIYGHTGIITDVSNSGQSFSTVEQNAEQGRIMARYQRGYNQAKIRSL
                     VRKVK"
     gene            10609..11121
                     /locus_tag="ACF3UF_002243"
     CDS             10609..11121
                     /locus_tag="ACF3UF_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFD3672323.1"
                     /translation="MKKYYFFFLSCFCLFGLTSCGWIFSEEKTEVSLISKEKMIQAES
                     SSKESKRNQEDKTECNISEEIQYLLKNFGRKWVNYTDIYERNQSVKNYLTDRCIKENG
                     IDNDPHIQYKTIGRIHTITQDVIQSDQYLLFGEETTNEITRFVLLQIKVDQEVQKIDK
                     IKIYYVRSAY"
     gene            complement(11240..>11485)
                     /locus_tag="ACF3UF_002244"
     CDS             complement(11240..>11485)
                     /locus_tag="ACF3UF_002244"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3672324.1"
                     /translation="TPDPETPVTPENPEPDKPVSLKNTNSKILISEKNVSNTNSKSNN
                     TLPQTGEKESSGVLAGLVILLASIAVGIKLNLKRKNI"
BASE COUNT         3844 a         1725 c         2450 g         3466 t
ORIGIN      
        1 tcttcacaaa cattcatata ataatagttt tatttaataa atacattgtt tttaaactaa
       61 tttctatatg tgttttgttg aactaactct tgacataaaa tttaaaagga tttatagttg
      121 ttaccgtagt agctactaaa agataaagtg aggattaatc aatggaaacg attattcaaa
      181 tcatgaaaaa atatgatttt tcagagatgg aaacaagagt gtataccaca ctattggaaa
      241 aaggcaatct tacaggatat gaagtaagta aagtctcagg tgtgccacgc tcgaaagtat
      301 ataacatttt ggaaaaacta ttaaaaaaga atttgattgt cgtcaataaa tcagaaccta
      361 aactttatca tgccatctcg gcaaatgagt ttttagagaa attagaaaaa agtgttaaaa
      421 atgatctctc ttttcttact caaaatctag ggatgatcaa agaaaaagat gaagaagaaa
      481 tgctgtggaa agttgatggc atcgagtatg ttctggataa agcagagcat ttggtgaaaa
      541 atgcaaaaga aagtttgctc atccaagttt ggcatgagaa cctcacggat tcactgctaa
      601 agacattgca gcaggctgaa aaaagagtcg ataaatttgt actgatttta ttcagttcta
      661 gccatgaata tgatcttccc ttagaaaagt attacattca tggttttgaa acagacaaac
      721 tcgctgactt tggggcaaga tggataaaca tcgtcgccga tgagcaagaa gtcgtgtttg
      781 gcaccattaa cgaagaactg caatcaaccg atgtcacttg gacaaaaaac cacgccatgg
      841 tcaatctagc aaaagaatat gtcaaacatg atgcatatac actaaaagtg attgcagaat
      901 cttctgaaga acttaaagca aaatatggtg aggactttga gggaatcaga aagatttact
      961 agtaggagga aatttttatg attcggaata ttttgctggc actaattgtc gcaatcaatc
     1021 tatattttat tatttacttt ctaagagacc ttttcaaaaa caaacaaaat ttcaaagaag
     1081 aaccagggga tatgcgtctg ttgcccttca cgtcatttat caccttcttt ctttcaacat
     1141 ttggcgtttc cgactttgct atcggaaccg tcctttatcc aaagttgaaa tgggtcagca
     1201 tgaaaaaact acccggaacg ttgaataccc aatgtgtcgt accggtagcc gtcatggcat
     1261 tgtcttatat cactgccatc aacgtagggg tcaagacact agctgtttgt attatctgcc
     1321 aaattatcgg tgcatattta ggaccaagat ttgtcgtgaa attaccagaa aaaacgatca
     1381 aactatttgt cggcatagga ttggtcattg ctgcattctt aatttttatg ggacaaatga
     1441 attggattcc ctcaaacgga acagccagtg aattgtatgg cggaaaatta atcttggcag
     1501 gatttttact ctttgtctat ggcgcattga acaatattgg cattggttct tatgcgctaa
     1561 cgatggtaac tgtctacttg ctaggcttga atccagttgc agcctttcct attatgatgg
     1621 gggcttgtac attctcagta ccgatcggca gtgtccaatt cattaaattt gatgaataca
     1681 gcagaaaaat cacacttttc acttcaacct tcggtgtatt aggggtattg gtcgctgtat
     1741 tcctagtcaa atctttagat acctatgtct tgaaatggat cgtaattttg gtcttactat
     1801 acagtgcata cacaatgttg ggcagtcaat taaaaaaagt ttcagcagct aattaaggag
     1861 cgattcaaat gttatttctt aaaaaagaag atattatcaa aagtttctca atgagagaag
     1921 ccatcgatgc agacaaaaaa gcattgtcat tgtattcagc aggaaaggca agtgtgcctc
     1981 ttcgcaccaa tatcgatgtg ccaaaaagca acggacaaag cttatatatg ccagcttatg
     2041 tagaaggtgg cgaaggtgcg ttaggtgtca aaatcgtttc cgtgtatcct gaaaacctca
     2101 agaaaaactt accaagtgta ccagccacga tgatcgtcct tgatccagaa acgggtatgg
     2161 tatccgcttg tttggatggt acctatttga cacaattaag aaccggcgct gttcaaggtg
     2221 cagcaacaga acttcttgca agagaagatg ctaaaatcgg cgcactgatc ggaaccggcg
     2281 gacaagcaca gtcgcaatta gaagcgatgt tgaccgttcg taaattagaa gaagttcgga
     2341 tttttgatat tgattttgac cgtgccagcc gatttgctga agaaatgatg caacagtttt
     2401 ctgtaacgat gcgcccaaca aaaaccagtc aagaatgcgt tgaaggagca gatatcatta
     2461 caagtgtgac cacttcaaaa cgtgcgacat tctctgctga gtgggtcaaa aaaggtgcgc
     2521 acatcaacgg agtcggtgct tacacaccgg aaatgtgtga aattccacga gaaataatca
     2581 aagccgcaga tgttgttatt tttgatacca tggacggtgt tctaaaagaa gctggggact
     2641 tcatttcacc gctgcaagat gggtatattc aaagagacag ttatcatggg gaactaggcc
     2701 aactgatcaa tgaagaattg atcggtcgga caagtggaga acaaatcaca attttcaaaa
     2761 cagttggttc ggctgtatta gatgtggtag ttgcgacaga aatcgttaat aaagctaaag
     2821 aaaataattt gggaaaattg atttattaaa taaaaagacc ggaagtaaac ctttaattag
     2881 tacatttata aaaagagaac aaaaaagact gtaatcaaaa tgcgattaca gctttttttt
     2941 gttttatttg ggaggagata gatcgtgttt atgactgtat cggatcattt aaaggtactt
     3001 ggttttatcc ctttatctag tagagggaag tatcaattgt atttgttaga tttaccaccc
     3061 tagcttttca ctgatgattg aaggaacata cgataaaaaa agtggtaagt atttttatga
     3121 tttttattct atgaaacttg atcctaaaac aaagaaaagt acgcagcacc ggatttattg
     3181 tacgcatgtt cctgtaaaag taatgtatcg tcgtgtgaga aattatttat acttcttacg
     3241 taaaaaacag caatcaagga acagaaaaaa tgcataatga ggaatatcaa gtgaaatttt
     3301 tatcagtttt gctctgtggt attgtgtatt gtcattagtt caatgagtat taacagggag
     3361 gaaaaagcaa atgaattttt ttcaaaatgt gtttaccgat tttgttgggg attttaagta
     3421 tttgattatg ttggcgatgc ttggtggtgc ggcatatatt gcctttgaac ggaaagcaag
     3481 caaagccatt ccattgattc ttgtgctagc agtagctgtt tggttagttg gagatacgtc
     3541 tggcgtattc aattggattt tggatcgtat gcggtcatgg gggcgataaa atgagtgaaa
     3601 tacgcaattg gacaaagatt tggtatatag agcgagtgtt ttataaattg tgggatgggg
     3661 tcgcgttacc tcgtcctgta acacaaacat ttgcgatatg gtttgggatt ggcttttttg
     3721 gggggatttt tcgaattttt ccatttgtta tggaacatac gattactcga caattttttt
     3781 gtccgtggtt atttgctttt ttaatgacac gaaaacaatt tcaaggaagg aagccttata
     3841 attatttggc ttcttttctt ttatttcagt gtcgttcaaa agaatccttt catggccaat
     3901 gggtaaagcc aatagaaaaa aaagaaatca aacgaggaat tcgttgtgta gtacgttatg
     3961 gaggtgaaaa ggatgcgact accaaaacta gtgcctaaga ttccttttta ttatttagaa
     4021 gacaatttag tttttggaga agaagatcgt gtgtacgctt attatgaatt cccaatgtat
     4081 tcatatagct tcgtgggaga agatcaggcg tatcaactcc aacaagcaat catgcgtctg
     4141 attcgtcaaa gtcattcttc gcatgttcgg ttcttttttt gtacaaacga agaaaaaatt
     4201 gaaaaaacga ttaaatcctc aaaagaattg gtgcgttcta aaggggaatt aaaaacgatt
     4261 gcctaccaac atttagaagg tgttcagcac attttagaag agctacatgg aaaatatatt
     4321 caaaatgttt gctggtatgt tgggattgag ctggtattag aagaaattgc tcccaaagaa
     4381 gctcattggt taaaagaatt tcgtattgcc gcaaaagatt tttttcaccg atccaatgcc
     4441 cgtttgtttg gagactttga aaccatccca aatgaaaaaa ttcaacgata taagcgattg
     4501 gagaatttat tgtataaccg gattagtaaa tactttcggt tacgaaaaac aacaccagaa
     4561 gacatggtgt ttttagtgga acatttagaa ggaaaaaaag aacaatcctt agatgaagtg
     4621 atgtatcgac caaatagctt taaagaagaa acgaatacgt atacgtatca ctatgatgta
     4681 ttgaatttgg ccagtgcagg aatcacagaa aagaaaaatt atctaatttt agaacaaggg
     4741 acagaaaaag aatatatcac gtatttatct ctttcacgta tgacccgtga tttggtattt
     4801 ccatttcaat cagagattta ttatttttta caatcggaat tggattttcc aatcgattct
     4861 tggttagatg tgaatctttt agataatcgt ttggccttgg cgaaagtacg tggcaaaaag
     4921 agtgatttat ctgatattta tgaaagtggt atgtcggttg gaaaagatgt aggaaacaat
     4981 gtacgcgaag cttaccaatc agccaatgag ttggaacaaa aattagaaga tacgcgagaa
     5041 gatttgtatg tattatcact aaacgttcgc gtgtcaggga agacctatga tgaaatgtta
     5101 aaacgtgtga gtgatgttcg caattttttt gatgtctatt ctatgtattt agaagtaccg
     5161 tgcaatgtac agctgctttt acattttgga agttatccag caggaaggcg agtgattgag
     5221 gattatcgtc aatatgtagg cgcagaattt attgctagtc ttggcattgg tgcgacacaa
     5281 caactaggag atggctgtgg tattccgatt ggatttaatg cagaaacagg aatcccagtg
     5341 tttattaaac catggttagc ggcacaagga ataaaaggaa cggttaccaa tactcttgcc
     5401 aaagcattaa ttggttcgct aggtggtggg aaatcattaa ctgagaatct cttgttattt
     5461 tggtcggtgt tgtttggcgc cttggctttt tgtatcgatc caaaatcgga acgttcaaat
     5521 tggtccgaag atttgccata ttttgccccc tacttaaaaa cagttaatat taccagtgag
     5581 aaagaaaata ttggtttact tgatccattt caattgatga gaagaaaaaa agatcaagaa
     5641 agtttagcat tggatgtgct cacctatatc acgggtgtaa gtattcggga cgaagaccgg
     5701 tttcctttgt tacaacgggc agttaaaact gtttctgatt ttgagggaac aaaaggatta
     5761 cttctagtaa ttcaggaatt atatgcacaa gaagcagcga ccgcacaacg cctggcaaag
     5821 catattgaaa gcttcaaaga actatctatt gcaggcctat tatttggaga tggcacgaac
     5881 caacaagggt taaatttgga tgccaaatgt aatctcgcac tggttcagga tttaacgtta
     5941 ccagatagtg aaactgtacc tgaggactat aactcttctg aaattttaag tattgcgatt
     6001 atgatgagtt tggctacgta tgcgctagat tttattaaac aaaatcgaaa aatttataaa
     6061 gcggttggct tagatgaaag ttgggcgtgg ttgaatgttg cgcaaggaaa aattttagga
     6121 gataaattgg ttcgtgaagg aagatctcgc aatgcaggga ttgatttttc aacacaaaac
     6181 acagatgatt taggtgatga aaagatgaga agtaaaattg ggttgaaatt catttttcgt
     6241 tcgaatgatc gcgaagaaat taccaaagca ttaagctttt gtggaatatc tgtcacagaa
     6301 gaaaatatcc agcgtgtaaa aaatctagaa aacggtgaat gtctgttttg tgacatccat
     6361 ggtaatattg gcattttgta tgtgtattat tggtttgaag atttattcca tgcatttgat
     6421 acacgaccgc caatggaaga aacctacgaa gaggaagaat ataaagacga gatattagaa
     6481 aaactggttg aagaaattga ggtgaattag atgaaacagt ggtattcaaa ggtttcattt
     6541 ttaattactc gccggaaact ggttttcata agtctagtca taatgatggg tgtttttttc
     6601 tttcacccat cattagtaga agcagctggt tggataaaag aaaccctagg cggcaaaaat
     6661 gccgtatatg attttgaaac atatccttta gataattata atttagattt ttttgtggat
     6721 acgtcgtgga attggttgcc gtggaaatgg ggtgaaggaa tttctaatac agttatttat
     6781 gggatatttg ccgttaccaa tattttatgg atgttaaatg tctacctgtg ttacttttta
     6841 gggtttcttg tccaagaagc ctttgaatta gattttcttt cagagttgat tggttcgtta
     6901 agtcatacaa ttcagaatat tgctggaatg aaccgtacag ggacattgag tcatggatta
     6961 gtccctttct ttggtggatt gttaattact ttagcaggtt gttcagtagt ttatcaagga
     7021 atagtgaaac aacaccctac gcaagctatt caacaagcgg tgacattttt gtttactttt
     7081 atttgttgcg gcgttttctt tatgaataca aacacatatt tagagaaagc taatggggta
     7141 caaaaagaaa tcaatagtga aatgttaacc attgccaaaa atctgttacc tgaacaaaaa
     7201 gaaaaaccag atgcaattaa ggccattcgt gagaatttat ttgccattca aattaagcaa
     7261 ccctggctag tgatgcaatt tggggatagt gatataaaaa cggttggtga agaacgtata
     7321 atcaatttat taaaagaatc accttatgat gaaggagaac agcgaaataa gcttgttgaa
     7381 gaagaagtaa ccaaacaaaa aaatggccat ctttcggtac aaaaagtgta tttgcgtttt
     7441 ggtatggtat ttttaacgct catcgtcaac attgtcatta gtatgagtgt tttggtatta
     7501 atcgttatct taattgcgtc gcaagtatta ttcttgttat ttataggatt cttacctgta
     7561 gcgatgattt tctcgttatt tccaaattca ggatcgttat taggtaatgc cttacagaaa
     7621 gtctttcaat tattgtttac aaaaatgggt attttactca ttttaaccat tactttttct
     7681 attagtcatg agttaaacca cttatccaag gacaaaggaa tgatttggac cagtttctta
     7741 caggtgacgt tatggttatc tgtctcgaca cgtgtcaatg aattattagg ttggatgaaa
     7801 attggtggcg tacaaacacg agctggggat cgaactggac gtttcttacg tggcatgatg
     7861 ttaggtacaa tgggtcaaaa aatgatacga ggaattggtg aaaattttgt tgggggtact
     7921 gccggaggtg tagctggcca aatgatttcc aaatctatga gtggtcaacg aagtatagct
     7981 tctacacctc ttatagagcg agtaggaaaa aaagtttcag ctatgacaga attaccggca
     8041 acgattgaaa gtagggcaga acaatggaag cggacaattc agtatgtccc aaccaatgcc
     8101 caatacaaag cacaaaaaat gaaatacgat tatttctctg ggcgaatgaa tgagtcggaa
     8161 cgacaaacac gagcgcgtaa ccttgcgaat gagcgacaga agaattttta tgaagcacga
     8221 aaagatgcat tgcaattaga gcaacaagag agaaaacaac gagcgatgcg ttcaatggcg
     8281 catcaaacag gaaaaacaca agtgacttct ggtaaattac aaacacggaa aagtgcaatg
     8341 attggtcgaa cagaacaatt tcctacgata gaaaaaagaa gtaacatttc aaatatagct
     8401 aaaaataaga aattgtcgaa gcaggaacat ccgattcatg aacgaagtac gaatcgaaag
     8461 attgaaactc cggttcgttg gacttcgact tctcgtcaaa acgcgagaaa aggtagaact
     8521 aaaaaagaat aaggaggagg gctatgtttc ctcggaagaa aaaactgtct attctctctg
     8581 aacaagaaac aagactaaaa ggaaagaaag acaagaaaaa agaaagctat aagggagcgc
     8641 gaaaaaggcg cttccttttt tttgtaggct ggagcttttt ggtttttagt gtttgttttg
     8701 gagtttataa taatttaact tctcaagata cgcatacaat ccatgaaaca aaagtcattg
     8761 ataaacaatt aaaagatatg actggaatag aaagttatgt gaaaaatttt gcatttttgt
     8821 attttacagt gagtcttgaa agcgaccaac aaataaatcg atcaaaagca gtagaaagtt
     8881 atttagctga tgggctgcaa atggataatg aaatagataa agacatagaa acgaatgtaa
     8941 aagttaaaaa tgtctcgatt tgggcaatag aggaacatga atcaaaaaaa catacatttg
     9001 tggttatgtt tcatgtctta ttagagatag aaaaagaatt caaagagcgt gtgtataagg
     9061 tggaggtata tcgaaacgaa ttatcatatg ccatagtgaa attgcctatt gtagcgagta
     9121 atgttaaaaa agcaacgatt aaagtagaca ctcggttcga aacaacgagc atttctcgaa
     9181 aagaacagga agaattagag aaattcttat ataccttctt tcgtatttat cctaaagcaa
     9241 acgcagaaga attaaaatat tatgggacaa ctcttttacc aattcaacag cctttagcct
     9301 ttgaagaact atcgaatttg caagtcgcaa aaaaagaggg tagatatgag attcattgta
     9361 atattttgta tcaagatcaa gaaacgcacc tttggtttac catgtactat gaaatgtcta
     9421 tgaaacaatt agagaatggg aactttcgaa ttgaggcgat tcattagtga aaaagatttt
     9481 tttatttagt ggcatctgta tgatgagttg tctgttttta ttatttgcga taattagcat
     9541 gtctagtggt gaatcgaagc acatggattc agcagttggt gttactcata cgggagaata
     9601 tatcgaaacc ttacctattt tttcagagat caaagggcgt ggtccgataa cagatgaaca
     9661 tgcccaagca gcagttggtg cagctgtaaa gtatcagtta ttaccgagtg tgattctttc
     9721 tcaattagga tatgaatcag cttatgggca gtcacaatct ggaagaaacg atacgaactt
     9781 ttttgggatt acgtggtttc ctggttgtcc ctatccacaa ggttctgcac gtgggattgg
     9841 tggttctgaa ggtggtttct atatgaagtt tccgaacctg aatgcttgtt atgactatta
     9901 tggatttatg gtggcgagtc aaagcaactt taatcaatgt gtgggcaata aagatcctgg
     9961 aagttgttta ttgattctag gtcgtggagg ttatgcggcg gcaggtatca ccgaaggcag
    10021 ttcgtattat caaggcgcaa taagtatcat aaagtcctat aacttaacgg aatatgatgc
    10081 ctttgcgatc aagcattgga atagcctacc aatcaaaaaa acttcgctta ttgcaggaaa
    10141 aagtaaaggc aatgcgaagg ttttggatcg gatcattgga cgacccgtaa ataatgggga
    10201 atgttatggt ggtacggcat ggtatgtatc tcaactaggt ggcccacagt taatgggttc
    10261 tggacacatg tttgcgatgt taatagggga agattataac tgggcaacct atggttggca
    10321 agtgatcatg aatccaaagc ccagtgactt acaagcagga gatgtggtca attggcaagc
    10381 aggtggtgca ttgtctcctg gaatctatgg ccacacgggt atcataacag atgtctcaaa
    10441 tagtggacaa agtttctcca ccgtagaaca gaacgccgag caggggcgaa ttatggcacg
    10501 gtatcaacgc ggctataacc aagcgaaaat tcgaagtctg gttcggaaag tgaaataaaa
    10561 gaattctttc gatgaaaatt tttagtagaa aagggagaag gatcgattgt gaaaaagtat
    10621 tattttttct ttctaagttg tttttgtttg tttggactta ctagttgtgg gtggattttt
    10681 tctgaagaaa aaacagaagt ttccttaata tcaaaagaaa agatgataca agcagaaagt
    10741 tcaagtaaag aaagcaaaag aaatcaggaa gacaaaacag aatgcaatat ttctgaagaa
    10801 atccaatatt tgttaaagaa ttttggaaga aaatgggtga attacacgga tatatacgaa
    10861 cgaaatcaat ctgtaaaaaa ctatttaacc gatcgttgta taaaagaaaa tgggattgac
    10921 aacgatccac atatacaata taaaacaatt ggccgtattc atactatcac acaagatgta
    10981 atccaatcgg atcaatattt attatttgga gaagaaacaa caaatgagat aactcggttt
    11041 gtgttacttc aaatcaaggt ggatcaagaa gtgcagaaga ttgataaaat caagatttat
    11101 tatgtaagaa gtgcatatta aaataaaaaa ggaattgtgg aaattgtttg taattaaatc
    11161 gaacagtgat tatttatttt aaattgaaaa cagagatagg atgaatactt attctatctc
    11221 tgttttcttt tggactaatc tagatatttt ttcgttttaa atttaattta atacccactg
    11281 caatagaagc taataaaata actaatccag ctaaaactcc tgatgattct ttttcaccag
    11341 tttggggaag agtattattt gactttgaat tagtatttga aacattcttc tctgatatta
    11401 aaattttaga gttagtgttt tttaaagaca ctggtttatc aggctcaggg ttctcaggcg
    11461 ttactggagt ttccggatct ggagt
//
LOCUS       DAXLPY010000075        11148 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.075, whole genome shotgun sequence.
ACCESSION   DAXLPY010000075 DAXLPY010000000
VERSION     DAXLPY010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.075"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            6..305
                     /locus_tag="ACF3UF_002245"
     CDS             6..305
                     /locus_tag="ACF3UF_002245"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3672325.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACF3UF_002246"
     CDS             378..1739
                     /locus_tag="ACF3UF_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFD3672326.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACF3UF_002247"
     CDS             1761..2021
                     /locus_tag="ACF3UF_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672327.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACF3UF_002248"
     CDS             2035..2787
                     /locus_tag="ACF3UF_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFD3672328.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACF3UF_002249"
     CDS             complement(2881..3486)
                     /locus_tag="ACF3UF_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3672329.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="ACF3UF_002250"
     CDS             complement(3542..4516)
                     /locus_tag="ACF3UF_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFD3672330.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5613)
                     /locus_tag="ACF3UF_002251"
     CDS             complement(4894..5613)
                     /locus_tag="ACF3UF_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3672331.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACF3UF_002252"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACF3UF_002252"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFD3672332.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="ACF3UF_002253"
     CDS             7164..8561
                     /locus_tag="ACF3UF_002253"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3672333.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="ACF3UF_002254"
     CDS             8642..9082
                     /locus_tag="ACF3UF_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3672334.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="ACF3UF_002255"
     CDS             9229..9555
                     /locus_tag="ACF3UF_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3672335.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="ACF3UF_002256"
     CDS             9556..10305
                     /locus_tag="ACF3UF_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFD3672336.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="ACF3UF_002257"
     CDS             complement(10331..10741)
                     /locus_tag="ACF3UF_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3672337.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3536 a         1948 c         2291 g         3373 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagtttcgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaatt
//
LOCUS       DAXLPY010000076        10846 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.076, whole genome shotgun sequence.
ACCESSION   DAXLPY010000076 DAXLPY010000000
VERSION     DAXLPY010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.076"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(135..1715)
                     /locus_tag="ACF3UF_002258"
     CDS             complement(135..1715)
                     /locus_tag="ACF3UF_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFD3672338.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2116..3492)
                     /locus_tag="ACF3UF_002259"
     CDS             complement(2116..3492)
                     /locus_tag="ACF3UF_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFD3672339.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3620..4708)
                     /locus_tag="ACF3UF_002260"
     CDS             complement(3620..4708)
                     /locus_tag="ACF3UF_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3672340.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            4880..5314
                     /locus_tag="ACF3UF_002261"
     CDS             4880..5314
                     /locus_tag="ACF3UF_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3672341.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5392..5925)
                     /locus_tag="ACF3UF_002262"
     CDS             complement(5392..5925)
                     /locus_tag="ACF3UF_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFD3672342.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6019..7197)
                     /gene="mutY"
                     /locus_tag="ACF3UF_002263"
     CDS             complement(6019..7197)
                     /gene="mutY"
                     /locus_tag="ACF3UF_002263"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFD3672343.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7190..7987)
                     /gene="recX"
                     /locus_tag="ACF3UF_002264"
     CDS             complement(7190..7987)
                     /gene="recX"
                     /locus_tag="ACF3UF_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFD3672344.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8094..9476
                     /gene="rlmD"
                     /locus_tag="ACF3UF_002265"
     CDS             8094..9476
                     /gene="rlmD"
                     /locus_tag="ACF3UF_002265"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFD3672345.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9650..10228)
                     /locus_tag="ACF3UF_002266"
     CDS             complement(9650..10228)
                     /locus_tag="ACF3UF_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFD3672346.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10550..>10846
                     /locus_tag="ACF3UF_002267"
     CDS             10550..>10846
                     /locus_tag="ACF3UF_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFD3672347.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFN"
BASE COUNT         3231 a         2186 c         1874 g         3555 t
ORIGIN      
        1 acatttctat gattttaata tagtaaaaag agccgtcacg gaaaatccgt cacggctcta
       61 aacaaaatat gagaggctgt ttttgtttgg ctattcttat tacttgatgc agggcagctt
      121 gtgtcaagac ttctttacat caaacttttt aattttacat tgggatattt atccgcaaac
      181 cagcgttctg caaattggtt ctcgaataag aacaacggtt ggtcgaaacg gtcacgagcc
      241 aagatattgc gacttgaact catcttctca tccaaatctt ctggatcgat ccagcgagcg
      301 attttgtgtc ccattggaga catgattact tcggcgttat actcatttaa catacgatat
      361 tggaatactt cgaattgtag ctgaccaaca gctccaatga tatattcttc cgttagatat
      421 gttttataaa gctgaatcgc tccttcttga actaattgat agattccttt gtggaaggat
      481 ttttgtttca tgacattttt tgcagtcact ttcataaaca gctctggagt aaatgaaggg
      541 agttcttcat aagcaacttt tagttttcct tcgaacaatg tatccccaat ctgataattg
      601 cctgtatcat atacaccgat gatatcgcct gctactgctt tttcgacgtt ttctctcgaa
      661 tctgccataa attgtgtgac attgcttaat ttcagttttt tatttgtacg ttccaaccag
      721 acatccattc ctcgttcgaa tgttccagaa cagattcgga caaaagcgat tcggtcacga
      781 tgggctggat tcatatttgc ttggatcttg aatacgaaac ctgaaaattc ttcctcataa
      841 ggacttacca tctgatcatc ttgtgttttg tgtccataag gagctggtgc caattcaacg
      901 aaagtctcta aaaaagtctg tacaccgaag ttagtcaatg cagaaccaaa aaatactggt
      961 gtctgatcgc cacgagcaat tttttcttga ttaaatgcat ctccagcctc tttgattagt
     1021 tctacttctt ctaagacttg ttcatataag gaattttcag ttagaggatg attttcggga
     1081 agcagtccat cttcatccaa ttctactaat cgttcatcct gataattttc cggacgataa
     1141 aactctacac gattatggta gatatcataa agaccttcta gccctttacc cataccgatt
     1201 ggccaattca tcggataaga ttcgatatct aatagctctt ctaattcttc taacaattcc
     1261 aatggttcac gaccatcacg atctagtttg ttgataaaag taaatatcgg gatgccacgt
     1321 ttttttacaa cttggaataa tttctttgtc tgtgcttcga tcccttttgc actatcgatt
     1381 accatgaccg cactatccac ggccatcaaa gtacgataag tatcttcaga aaaatcttca
     1441 tgtcctggtg tatccaagat atttactcgt ttcccttgat aatcaaactg cataacagaa
     1501 ctagtaacag aaatcccacg ttgtttctcg atttccatcc agtctgattt ggcaaaatta
     1561 cctgtttttt tgccttttac ggtcccggct tgacggatag ccccaccaaa caatagtaat
     1621 tgttctgtaa tcgttgtttt cccagcatcc ggatgggaaa tgatcgcaaa agttctgcga
     1681 ttgtccactt gttgctttaa ttttggatta ttcataacct aactccattt cttccattca
     1741 attatttata ttttctctag gcacagattg tccgatctct taaagaaaga caatttcata
     1801 tagggctgtg acaaaagccg tgtagcagtc tctttttccg agtaaacggc gttctagaga
     1861 cagcctatca gcaataagcc cacccaagcc aaaaatacga aaagctgttt ttgcttggct
     1921 gctcttatta cttaatgcag gatagctttt tcacaacctt tgtcaactac tacaactgaa
     1981 tcagtatagc atggattcag cgaatgaaaa agccaccaaa ccataagagt caaatatttt
     2041 tttgtcagct gactaaaaga aaagacgtgt tgcttgttta ttcaagcaac acgtctttca
     2101 taaccaagtt tccaattatc ttcttggctc gtcatcttcg aattcttttc tgaagtatct
     2161 tcgttcttct tcaggttccg cttctgtttc ttccggatca tgaaaaatga cacggatttt
     2221 aaggattcga gaaccttcca tttcttcaga aaccagcgta atattatcga catcaaacga
     2281 taacttttcg ccttcatccg gaatcatgcc taatgctgta atcaaataac cagccatcgt
     2341 atctacatca ctcatatgca gatcactgtc aaaagcttca ttgaactcat caatcagcat
     2401 acgtccttgg atgatatatt cgtgttcatc gattttttca taaagattct caacttcatc
     2461 tgattcatca tcgatttctc cgacgatttc ttctaaaagg tcttctagtg ttgctaaccc
     2521 aacgacgccg ccatattcat ctaataaaat agccatctga ttctgcgtct ttttcatttc
     2581 atataacaga tcatcaataa agaccgtttc aggaacgaat aaaggctcct gcatgatttt
     2641 cttgatatct aaattatcaa agccgaattt atgggcagct tttagtaaat tctttgtatg
     2701 aaggattccg actactttat ctttgtcttc gttataaaca gggattcttg aatagttttc
     2761 ggataaaact tcattcacat tttcttccac agtgtcgttg atatcaatca taaatgcatc
     2821 cgttcgtggg accatgactt ctcgggcaac tttcgtatca agagaaaaaa ccccttggag
     2881 catttctaat tcttcattat tcaatacgcc ttcgttttca agcatataac gcatttcatc
     2941 tctggtcatt tttgaatctt catcatcaaa agtcatcggc gtgatacgcg ccaataaact
     3001 tgtggaagca gaaagcagcc agacgaaggg cttagctact acaccaatca agcgtatcag
     3061 ccctgaagtg aactttgcga cttcttctga tttatttaaa gcaatacgtt tagggtacaa
     3121 ttctccaaaa acaatcgata cataggtcaa aatagccagc acaatgatat ttgcaatatt
     3181 ttttgccgct gtgccgccac ctaataccgg agctaaccgt tccgataaag tattagctag
     3241 tgaagcacca gacaaaatgt tgaccaaagt gattcctact tggattgtcg ataggaaatt
     3301 atttggattc tgcaatattt ttaaaagctt ttgagatttc acatctcctt catcagcttt
     3361 ttgctcgatt cgattcttat tgatcgaaac aacagcaatt tcggaagctg ctaaaaaagc
     3421 attgatcaat gtcaaaacga tcaataataa aatctgcgct aacagcgact gactctcagg
     3481 gtcagcattc ataatcgcat tctctcctta taaaattaat ttttagttta cgatagaaaa
     3541 aaacgtggca ctatagccac gttaaaatgg tatcacaaag caattttctt tgcaataaaa
     3601 acaagtgtac taaaactacc tacgaggtcg tagcaatttt cttcttgttt tcattttgct
     3661 tgtcttcttt gacgattttg attatatagg aaatgatcgt cttgcagatt gcgtaaaaag
     3721 gaacacctaa gaagatacca agcaatccgg caatatttcc agctactaga agaacgataa
     3781 tgatcgttaa tggatggatt ttcagtgatt tcccaattac attaggataa atgatattcc
     3841 catccaactg ttggacgatt agcacaacca cacaacaaag taatgctttt accggatcat
     3901 tgaagactgt tactagaaat gcaggtgcta gtcctagata aggtcctaaa tatggaatta
     3961 ggtttgtcaa tcccgcaatg accccaaata agaaagcata atccacacca attaccatat
     4021 atcctaaaaa tgtgaaggta ccaacgaata aacattcgat tgcttgtccg ctaatgtaat
     4081 tagccaatgt tttattcagt tgccccaata actccacaat ttggtttctt cttttttctg
     4141 ggaaaaactg ttggatgttt ggcactagtt tttctccgtc tttcaacata tagaacaaga
     4201 tgaatggtgc tgtaatgatt actacggttg ccgaagcgat cgttccaacg atcgaaccta
     4261 aactattgga tactccacta aggaattgct gaatgattgt cccgtaagaa atgtctaatt
     4321 gctcaaaata tttattgata tctacttcct tgaacaaagg caattcggct acctctttta
     4381 accagctttc tacctgtttg atgaaatcag gcatattaga tgccaatgag gaaatttgct
     4441 gtactagact tgggatgaca ctaagtaaaa tccaaataat tgctgcaact aaaaggagca
     4501 gcacaattgc gacagcccat attcttttga tttttgcttt catcaacagc ttgacaatag
     4561 gattcaataa atagtaaaga aagcctgcaa tcagtacagg tgcaaataac gtggaaaaaa
     4621 atgtcccgat cggttcgaaa ataaagttta tttctgatga aatcatgatc aatgcagcta
     4681 tgatcaataa ttcaagcgac caaaacatta gtttagactg tctaagtttt tcaaacaata
     4741 gatttcctcc tttctttctt actagtatat attatattcg ttaaaaattc ttttattctt
     4801 tttttatttt tgaaaacttg ccatactttt tatttgtttt attttccagt atactatacg
     4861 aaaggaaggt ggctagacca tgaaagttgt acaaacaaaa gatacaatga gcaatattta
     4921 cttagatgct gtacggatca ggcatcaagt ttttgtagtc gaacagggtg tgcctttgtc
     4981 tcgagaaata gacaaagatg aagcccattg tatccacttc gtcctgtact cagataaaaa
     5041 agaaccgcaa ggaactgtac gtcttttgcc tttagaaaac ggaaaaatga aattacagcg
     5101 gatggcgatt ctttctgaat acagacacca agggttagga aaaatattga ttgaagaagc
     5161 agaaaacttt gctaagaatc aaggctataa tacgatttta ttaggggcac agtccacagc
     5221 tgaaactttt tacgaaaaac taggatatac agcttacggc gatccttttg aagatgctgg
     5281 catgcctcat atttatatga aaaagacttt ataaaaattt atttcgaaaa aagcaaaaaa
     5341 cagcaagctt ttgagaaaaa tctctcactg gcttactgtt cttttttgtg tttacttacg
     5401 cgacaattgc ttgtaacggt tataccaaat atcaatatag ccttccgaga acgggccatc
     5461 tccattattg atccagtcaa ccagaatctt cacattttct tttaggatga agtcaatatc
     5521 gttcgggtaa ttcatcattt tgctgtgcat ctcatattca tcgacatcca atagtcgttt
     5581 ctcgccgtca ggaaatacct tgatatccaa gtcatagtcg atatatttca aggcctcatc
     5641 gtccagcaaa aaaggtgaag ctagattaca ataataggaa accccctttt ctctgatcat
     5701 tgctattaca ttgaaccagt attttttatg aaaataaaca atcgctggtt cgcgcgttac
     5761 ccatcggcgt ccatcagatt cagtgactaa tgtgtgatca ttcacgccga tcatagagtg
     5821 ttcgcttgtt tttaatacca tggtatctcg ccacgttcga tgcaatttgc cgtcgtgctt
     5881 gtaactttgg atcgtcacaa actctccttc ttttggaact cccatagcaa cccttcctta
     5941 agcagcattt tgtgctttgt gtttgggtgt tcattacacc gacatcataa ttattatatc
     6001 aataaaaatg agctttgcct agaaaggatt cctattgttt cgatttttct ctaactgatc
     6061 taccagtttc atttggacct taggaaaaac gaccgaatca aatgcatcag gcttcaacca
     6121 cttcgaagtt ttgttctcgg taaattcttg ttctgctccc tcggttgccc gtccgtaaaa
     6181 aaggagaaca tgccatttca gatgactaaa aatatgagta acttctccta aatgtcgtgt
     6241 ctgccaaaca aagagttcct gcttttcaaa tgggagattt tgctcttctt ctgctactag
     6301 gtcatcaaac agatcgattt ctggctttgt ttcccattct tttttcaatc gctcatactc
     6361 ctcttgtgtc acttccatca ttggaaatgt ccacatattc gccagcaatt tttggctatc
     6421 tctttcttca aaataatacg ctccagaatg attttgaaga gctgcactga tataataaac
     6481 gtcttttggc tttgcttttt ttgtttttac aggaaaactc gtttggattc ctcgtttgtt
     6541 agctaaacaa aaggcttgga tcggacaagt ctcacacttt ggagaagttg gtgtacagat
     6601 agctgaacct agatccatca ttgcttggtt gaattcacct ggatgctttt catcaatgat
     6661 tttccgcatc gcttcatcaa agattttcct gctagaagct tttgcgatgt ctgcttcaat
     6721 gcaaaacaat ctgctgacta ctcgcatcac gttgccgtca actgcaggtt ctggaagtcc
     6781 aaatgcgata cttgcaatcg cgcctgtcgt atatggtcct attcccttca atgagctaat
     6841 ttcttcaggc gtttgcggca tttccccatc aaattctgac atgatctgtt tagcagcagc
     6901 ttggatgttc cgggctcttg agtaataacc aaggccctcc catgctttta aaagcttttc
     6961 ttctggagca tttgctagct cttcaattgt aggaaaccat tccatgaaac gataaaaata
     7021 atcgatcact gtgtctactc tggtttgctg aagcatgatc tcagagatcc agatacgata
     7081 aggatcacga ttatagcgcc aaggcaggtt tcttttttct tgttcatacc attgaatgaa
     7141 ctgatcttga aattcttttg tttctttatc tgtccatttt tcccattctt tattcacttt
     7201 cctcttcctt ttccgtaatg aatcgctgga tcatatccaa atcaaatcct ttttgatata
     7261 agctttgctt tacttttaga tttctttttt taggttcaaa ccttaaattt cttcgccata
     7321 gtttatctcc ttgtttgact aaataatcat attctatttc ttgatctgct tcttgcggaa
     7381 gatcagctat cgcttgttgg atcacttctt gagaaaagcc tttcgtcatc aatgtttgtt
     7441 ggatttttct caataattct ttttggcttt ttccgtgatt ttttccaaac gctttttcgg
     7501 ctgtctgatg tgcattttga acttggtctt caaatgtata ttggctgagc gcttgttcaa
     7561 tgatttcagg tttcaaacct ttttgctgca tctgctgcgc taatttcttt ggtcctttgt
     7621 cacttaagcg catattcgtg cgcacataac tttccccata gaccaaatca tcgacaaggt
     7681 ccaattcttt taagcgggct acgattttat ttcgatcttc ttgaaggatt tccttttctt
     7741 ttaagtatgt tcggatttct ttttccgatc gcaactgata acttaagtaa ttcattgcta
     7801 ggtgaaaacc gaaatcagct ccgctactct tcttgatctc ttggatagtt tcttcgtcta
     7861 attcccgtcc ttttaataat cgatagcgta ctaatacatc ttcagatact tgtaaagctt
     7921 ctccttcaga taaatctacg cgatagaaag ggcctttgcc tttactgatt ctcgtaacgg
     7981 ttaacataaa catcctcctc gaacatatat tctctatcat accacagaaa atccccgtaa
     8041 tcaggtatta tatgttagaa taaaccacag aaaaaagaaa aagggagata cttatggcag
     8101 aaacaattgt caaaactgga caaacggttc ctttgaaaat caagcgttta ggcataaatg
     8161 gtgaaggaat cggttatttc aaacggttga tcatatttgt tccatatgca ctaccaaaag
     8221 aagaagtact agtgaaaatc acgaaagcaa ctcctcgcta tgcagaagga gaattaataa
     8281 aagtcaaaaa aacaagcaaa gatcgcgtag tggcaccatg tcctgtttac tatgaatgcg
     8341 gtggctgtca attacaacac ttagcttatc aagctcaatt ggattttaaa aaggatctgc
     8401 ttttgcaagc attggaaaaa ttcaaaccag caggctttcg atcttatcaa cttttgccga
     8461 cgatcgggat ggatgagcct tggcattata gaaacaaagc acaatttcag ttacgaaaaa
     8521 ataagcagac tcaaaaaatt gaagctggtt tatacgaagc aaactctcat cagttagtcc
     8581 ctataacaga ctgcttggtt caagaacctc gaacacaaaa agtaatgaat actgttgttc
     8641 aactattgaa taaatttgat gcacccatct atgatgaacg gacaaacagt ggaatcttcc
     8701 gcacaatcat ggttagaatc ggtgttaaaa ctggggagtt acaagttgtt tttattactc
     8761 gcagtaaaaa attcccgcaa aaaaacgcaa tgatccgtga gatcaatgaa cgactgcccg
     8821 aagttgtttc aatcatgcaa aatgtccagg cacaaaaaac gtctctcgtg atgggggatg
     8881 aaacgatcca cttatgggga aaagaagcca ttgaagaaca aatcaatgaa gtgactttcg
     8941 atctttctcc tcgtgccttc tttcaactca atcctcagca gaccgaattg ctttatggcg
     9001 aaggaatcaa agcattagat gtccagccta atgaaacgat cgtggatgct tattgcggag
     9061 ttgggacgat cggcttaagt gtagcaaaac aagccaaaga agtacgggga atggataccg
     9121 ttcctcaagc aatcgctgat gcaaaaaaaa atgcggaaag attaggatat cacaacactc
     9181 gatatgaagt cgggacagca gagcaagttc tgcctaaatg gttgaatgaa ggttttcagc
     9241 ctgatggtat catcgtagat ccaccacgta cgggtttgga taacgcattg atccaatcat
     9301 tattgaaata ccctccaaaa aaacttgttt atatctcctg taatgtttct acacttgcca
     9361 gagatctggt taatttaagt aaaaagttca agattgaata tttacagtcc gtcgacatgt
     9421 ttcctcagac tgcacgttgt gaagttgtcg tgaagatgac gagactcgct gactaaatga
     9481 aagaggttgt gaaaaagtct gccctgtatc aagtaataag aacagccaaa caaaaatagc
     9541 tcttcatgtt ttatgaatac tgtacttgtg accgaagagt taacaggagg acactattta
     9601 tttaaaaaaa gggttgtgac atagtttttg tcacagccct ttttgattat tattggatat
     9661 tcacgtctat cacttgataa aatgcatttg tcgtatcgct gatattccat actgctaaaa
     9721 tcacattata tccttttcga tcctgcggaa gtgtgatcgt ttggttgact gtttttggtg
     9781 gaacagttgc tttgtcgtct atttttgtga tcaattcaaa atcactaaat ttcaaaggtt
     9841 gattaggatt ccaagttggt ttggtaatgt agtaatccca agtacttgtc cgatgttgtg
     9901 ctgttaaatt ccaagtaata tttaatgttc ctggattaac catgttttta tgccatctgt
     9961 tagatgtctg ttcatctaaa ggctcaaagc cgctgactcc tgcactagca atttttccat
    10021 caatgaatgt atttttggta gcttcgatac tttgcggttc ccattgtgct cttccgacat
    10081 tttgatttaa gtttcctgct gctgatgttc ctaggtatgc acggcttcct ggagaagtaa
    10141 tataaccatg cgcaaaacct ggaatgctaa aaccgaacaa ccctaaacta actaacccaa
    10201 taaacaataa cgtactaatc tttttcatgt agaaacctcc ttcatttgat aaccacattg
    10261 taaacgcttt attgtattaa cacaaacatt atgcttttat aattttatgt tgaagtaaaa
    10321 aaggtgaaaa aagtaagatg cagattataa cagaagtaga cgagaaaagt acaaatagaa
    10381 aacatgagaa tcaaatcata tgatcttttt caaaaacatc attcatataa acaaatgttc
    10441 aactttttaa taacaacaat tatcaatttt tttcttactt cacaaactaa atacaggtct
    10501 tgctgtgagc cttcatggta aactactatt atagaaagga gttagtaaaa tgaagatgat
    10561 aaaagatatt cgtttttggg tttgtgttat aggaattgtc atattaggct ttttatcagg
    10621 gttgcttagc ggaaatcccg gagaatatta ctattctttg caacttccac catttgcacc
    10681 acctagctgg atatttgggc cgatgtggac cttactgtat atattgatgg gtatttctct
    10741 ttatttgtta cttaatcaca acaacaaaaa acagcgaaac aatcttgtcg gtctttttgt
    10801 gattcagttc atttttaatt ttatatggtc tgctctattt tttaat
//
LOCUS       DAXLPY010000077        10702 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.077, whole genome shotgun sequence.
ACCESSION   DAXLPY010000077 DAXLPY010000000
VERSION     DAXLPY010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.077"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(220..1068)
                     /locus_tag="ACF3UF_002268"
     CDS             complement(220..1068)
                     /locus_tag="ACF3UF_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3672348.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1232..2134
                     /gene="gnd"
                     /locus_tag="ACF3UF_002269"
     CDS             1232..2134
                     /gene="gnd"
                     /locus_tag="ACF3UF_002269"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFD3672349.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            2136..3137
                     /locus_tag="ACF3UF_002270"
     CDS             2136..3137
                     /locus_tag="ACF3UF_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFD3672350.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3134..3418
                     /locus_tag="ACF3UF_002271"
     CDS             3134..3418
                     /locus_tag="ACF3UF_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFD3672351.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3451..4248
                     /locus_tag="ACF3UF_002272"
     CDS             3451..4248
                     /locus_tag="ACF3UF_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFD3672352.1"
                     /translation="MGYSTNLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4262..5095
                     /locus_tag="ACF3UF_002273"
     CDS             4262..5095
                     /locus_tag="ACF3UF_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3672353.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5113..5970
                     /locus_tag="ACF3UF_002274"
     CDS             5113..5970
                     /locus_tag="ACF3UF_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3672354.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            5992..6501
                     /locus_tag="ACF3UF_002275"
     CDS             5992..6501
                     /locus_tag="ACF3UF_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFD3672355.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6538..6939
                     /locus_tag="ACF3UF_002276"
     CDS             6538..6939
                     /locus_tag="ACF3UF_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672356.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7051..7404
                     /locus_tag="ACF3UF_002277"
     CDS             7051..7404
                     /locus_tag="ACF3UF_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672357.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7438..7881
                     /locus_tag="ACF3UF_002278"
     CDS             7438..7881
                     /locus_tag="ACF3UF_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3672358.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7898..8983
                     /gene="uxuA"
                     /locus_tag="ACF3UF_002279"
     CDS             7898..8983
                     /gene="uxuA"
                     /locus_tag="ACF3UF_002279"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFD3672359.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            8976..9689
                     /locus_tag="ACF3UF_002280"
     CDS             8976..9689
                     /locus_tag="ACF3UF_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3672360.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(9896..10045)
                     /locus_tag="ACF3UF_002281"
     CDS             complement(9896..10045)
                     /locus_tag="ACF3UF_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672361.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            10441..10641
                     /locus_tag="ACF3UF_002282"
     CDS             10441..10641
                     /locus_tag="ACF3UF_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3672362.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         3570 a         1694 c         2317 g         3121 t
ORIGIN      
        1 agataaattt tttactactg tatactaact ttgttatcgc atctaacaag taactcgaat
       61 aataccaata caaccttctc caaagatgcg atgacatacg ttctaaccca ccgactattg
      121 atgttctgta ccacccttgc agaaccaaaa aagccactac catatatttg gtagtggctt
      181 tttttgtttt atggattttt cgctttttct gttatggtgc tattctttga tttcagaaat
      241 agtatgtcga actttagcga tagaacgacg tgattctttt tcgttgtaaa acatcaaaat
      301 cacatataga gagtccaaaa tgcttagttg agaaatacgg gaagctaaag cttcagatcg
      361 gaattctgtt tcttcagaaa tagaaataaa aacgacatcg ccaagtttag caagggaaga
      421 attagcttgg ctagtaataa cgattgtttt tgctccagtt tttcttacgg tttcagcaat
      481 atggattgtt tcttttgatt gccctgtgtg agaaatcaaa acagcacagt ctttttccgt
      541 caataaagaa gcttccatca attgaatatg gtaatccgtg ctgtgagaag ttgcgatagg
      601 ggaacgcaaa aatttatgat aagcgtcagt tgctacaatc tctgaaccgc caacaccgaa
      661 aaaatagaca cgtttagatt cattgataat agtagccgct ttttttagat ccttttgttg
      721 taacaacttt tttgtgtcat ttaaagttga aatactagac tcgaacacct tttgcgccat
      781 agtgagctca gtatctgttt tctgaatatt ttcgtggata gaaatagcag atagatcatt
      841 ttcttggatc aacatggcca ttttaaaatc tttaaatcca ttataaccaa gtttttttgt
      901 aaattgaaaa aaagtagagt cagcaatgcc cagttcactt gctaaattgc taataggact
      961 atgacttact ttgcttggat tttctaaaat ataatcggcg atagcctgtt cttttgggct
     1021 gaagtcgttg tacattgttt tgatttgtag tcttatggag acgctcatga gaattcctca
     1081 ttttcataat aagattatca ttttttccgt tctcattaat gttaaagata caaggagagt
     1141 aggaaaaaat caaacaaaaa atatttttgt aaaatctatt tacaaaaaaa tttttttgta
     1201 taatgagggt ataagaaatg gaggcgctat catggaaatt ggtgtaattg gtttgggaaa
     1261 aatgggattg aatttagctt taaacttaaa agagcaccat cacaaagtac aaggactcga
     1321 catttcaagt acagctgtta gtcaggcaag agaaaatgac attcctgctt atcaagagat
     1381 ctctgaattt ctagctactt ttgagcagaa aaaaatcatc tggttaatgc ttcctgctgg
     1441 agagataacc gaaaacatgt taagaaaact ttttccaaaa ctcggaccag gagacattat
     1501 tattgaaggc ggaaactctt attataaaga ttcaatccgt cgagcagaag agtttcagaa
     1561 aaatgaaatc ggttacttgg attgtgggac ttctggagga atcgaaggag cacgacatca
     1621 agcctgctta atgattggag gagataaaga aacttttcta tccgtggaac aattattcaa
     1681 agatgtagca attgaaagag gatatctgta tgctggtgca tccggaagcg gacacttctt
     1741 gaaaatgatc cataatggaa tcgaatatgg aatgatgcaa gcaatcggtg aaggattcca
     1801 acttgtacaa aaaagtgagt atgcttttga cttggaacaa gtcgcacgtg tttggaatca
     1861 tggttcggtg attcgcggct ggctgatgga aatcatggaa gatcagttaa acgaacatcc
     1921 caatttaagt aattatcggg gaatcgtttc tgcatcaggt gaagcaaaat ggacggttga
     1981 aacagcgcta gaaatggctg ttccagttcc agtaattgca actagtttgt tcatgaggaa
     2041 tctttcacag gaagaagata gtttttcagc aaaagtagtt tcagcactaa gaaatgggtt
     2101 tggcggacat gaaatagttg aaaagggtga gtaaaatgcc agattatcat atagcaatcg
     2161 ttaattccag cagtttcgga agagtctttc cacaccactt ggaaagatta aagtcagttg
     2221 gagacgttca tttctttact gttgatcaag agattccagg aaaagaacta gcggagttac
     2281 ttaaaggatt caatatcatt attgcaagtg ttacgccatt ttttcgacga gatttttttg
     2341 aaaacaaaga tgaactgcta ttgatttccc gacatggtat tggttacaac aatattgatt
     2401 taaaagcagc aaaagaacac cagacaatcg tatctatcat acctgcttta gttgaacgaa
     2461 atgctgtagc agaaaataat ataactaatt tgttgtccat gcttcgacgc acgacacaag
     2521 cacaagcaag agtcaaggac gatcgatggg aagatcgggc ggagttcgtc ggtaggacgc
     2581 tgtttaacaa aacagttggt gtgattggtg caggaaatac cggaagcgga gtaatcgaaa
     2641 ttttgcgtaa cggttttcgc tgtgatgttc tagcttatga tccttacaaa tcagatttat
     2701 acatcgaaag ctttggtgca aaaaaagtag aacttcaaga attactggaa caatcagata
     2761 tcatttgttt atgtgcgaat ttgacagaag agaactatca catgatttct gataaagaag
     2821 tcgatcagat gaaagaaaat gtttatctat ctaatagtgc aagaggcgct ctagttgatg
     2881 aagaagcgat gattaatggt ctgaaaagcg gaaagatcgc aggatatgcc acagatgttt
     2941 tagaagaaga accgggacgt caagatcatc cgtatttagc gtttgaacaa gtagtgatta
     3001 cgccacatat atcggcctac acaagggaat gtttagaagc aatgggtgaa aaatgtgtca
     3061 gagatgtcga acagatcagt cagcaccttc ttcctgaacg ttctgtccag acaaagagca
     3121 actatataaa aggatgatga agaaaatggt gaacggttta aaagtgaaaa caggccctca
     3181 attttattta tatgaagaag gtggtatttc aaaagtttct gatctcttga aatcatacgg
     3241 cgcgaaaaga gtactggtca cccacggaac ggtatcatgg gaaaaggcgc tacctaaatt
     3301 agtatttttg aatgacgaaa cgattcaatt tttttatcat cgttattctg gagaatgtag
     3361 ttatgctgaa gccagacgaa tagctacaat catcaaaaaa atgaaatcga tttcgtagtt
     3421 ggcgttggcg gaggaaaact gaccgatcta gtgggttata gtaccaatct tgcaagaatc
     3481 gatttcggag tcatccctac tttagctagt aattgtgctc catggacacc tcttgctgtc
     3541 atgtataagg agaatggaca agcagaaggg aaaacagaac acttttacag acaagctgct
     3601 ttttttataa cagatcccca attagtgatt gattcccctg ttccatattt cattgccggg
     3661 ttagcagata cactagcaaa atggtatgaa tctgagctca tcttagaaca agattttttg
     3721 caagatgaat catttttgaa gctagcacaa gatactgcga agatctgcaa agaagagatt
     3781 ttgaatcatt ctgctaaagc aatccaagat atggcacaaa gaaaactgac atcggagttc
     3841 aaacagcttt cagagattat ctttgctgtt gctggtttag ttggaggatt aggagataaa
     3901 tacgcaagaa atgcggcagc acatgctatg catgacgcta tcagtaaata tattccggaa
     3961 agccatcgtt ttctacatgg agaaaaagta gcgtatggga ttttctatca actggcacta
     4021 gaaggtcgct gggaaaaaat agacgagtta tatcctttgt atcgggaatt agaactgccg
     4081 gtttctctag aacaaatggg attatttccg aaagataaac agataataga taaaatggct
     4141 gaatttattg attcgaaaga gaaagtgcat ttgattccta tagaggtaac acagaaatca
     4201 ctgatacagt caatgatgga actggaaggt tatatcagaa agatctgaag gaggaggaca
     4261 catggaaaca ttaagtgtag tacaaagttt gttgattgct ttatgggtag ccgcggttat
     4321 gtcccgctgg ttaggtggag gagccacgtt gaccttacgt ttttctcctt tgatgactgg
     4381 attagtcgtc gggttgatca tgggggaagt tgcacaagcg atgattgtta cagccgcttt
     4441 gcaaatgatt tatatggggg ttttttctcc aggaggatca atgccagctg aaccatctat
     4501 tgcagcagct atcgcagtac cagtcgcatt attaggggat ctgtcgccag aagcagcgat
     4561 tgccgttgcg gtgccagtcg gattgctcgg aagttacttg tatcagtttc gttttttcat
     4621 caatactttt ttaggtaaat atacagacaa agctgtagaa gatttgaata caaaagctat
     4681 ggcccgatca attattcttt atccaacggt tgcctcattt ttattattcg ttccgcttgt
     4741 tttcattgct ttatatttag gggcgccatt gatcgctgat gtaatcaaag ctttagaggg
     4801 aacagtcgtt atccacattc ttgaagtagt aggtggaggg ttagcggcaa tcggtatcgc
     4861 gacaactgta tacgttatcg gtcgaaaaga ttatctggtc tttttcttcc ttgcttattt
     4921 tatgagtgtt gttttgaaat ctttagatat tacgatggtt acttatgcca tttttgggat
     4981 tattatcgct ttgatctttg tccagtcgca aaaagggaaa caagtacagc ctgccacaag
     5041 caataacaat tcagcatctt ttgatgacga agatgactat gatgacggat tttaatttag
     5101 gaggaatggg aaatggctga aataatggat aatcaaacag gtgctcctga agaaatcacg
     5161 aaaaaagatg taacaaaagc ctatctgaga tggcattttg caaacgaaat tcctcactct
     5221 tttgaacgtt acttggcgcc atcactacta tacggaatga tgccaatctt gaaaaaactt
     5281 tataaagatg aagactcttt aaaagcagca tataaacggc agttactgtt cttcaacact
     5341 caattaagct ggggtggcgg tgtgattact ggcctaatgt cttctatgga acagcaaaga
     5401 gcagaagaag agtatgaaga aaaagagatc ttgatgcagg atgacttgat gtataacacg
     5461 aaagcgggat tgatgggggc actagcagga atcggagatg caatcgattc aggaaccgtc
     5521 caatatattt ttatcgcaat cgcggtacct tgggcacaac agggaagtcc tttaggcgca
     5581 ctttttcctt ttatctgctt tgggttgtat caggttttac taggggtatt tttcgcaaga
     5641 caagctttca ctatgggccg taatgctaca ggcctaatgc aaaacactgg tgttcagaca
     5701 gcgattgaaa tgctatcagt tttagggttg tttatgatgg gggtgcttgc gggaaactat
     5761 gtaaaagtag aatcttcatt gaaatttgcg atatccggac gtgagtttgt tatccaggaa
     5821 attcttgatc aaatcgtgcc agggatatta cctttagctg tcgtaatggg tgtgtacttg
     5881 ttctatacga aaaaaggatt gaaagtcaca caagcattat tatggctgac tggaatatta
     5941 attgtgctag caggaatcgg tattttataa aaagaaggga acgtgaataa gatgggtgta
     6001 gtcaatttag cgcgtgtgga tgagcgtttg atccatgggc aagtaatggt aacgttatct
     6061 caaaaaagtg gagtgaattc catttttgtt gtagacgaag ttgtagcaaa agataaattt
     6121 atgagagatc tttacaaaaa tgcaggaagc cgtacaggac aaaaaacaat tgtcattaca
     6181 ccagagaaag ctaaattcta ttgggatgaa tatcaattta aagaatacaa ttgtattttg
     6241 atcgcaaaaa cagtccaaac gatttacgac ttagtaaaac acggaatccc catggaagaa
     6301 ttgaatattg gagggattgc tcaaaaaaat cctgatacag atcttttagt gacgaaatct
     6361 gtttatttaa ataaatcaga tgctgaaaaa ttgaaagaaa tgaatgaaca atatggcgta
     6421 aagaatattt attttcaagc cactccatct gcacctaaaa caggattaaa agatgtattg
     6481 aacaagtttg atttgtcata aacaaatgct tagaaaaaag ataaagaggg cgaaaaaatg
     6541 aagaagaacg agctgtttcg tgattgggaa tttcgttatc gctatattta ccgtaagcgc
     6601 cgtacaaaaa agagtaaaca gcgttttctt tcagcattag tatcagatat ttacagtatg
     6661 agaacagatg tgacagtcat tgcttacgat acgctagcct accgatcaaa aaatatttat
     6721 gttggagata tcgaaaaagc agagaaagtt atctgtactt attacgatac acccgttcat
     6781 gcattaggaa gttatttcat gtttgattgg aaagaccaaa ggaaaaaaac aatctactct
     6841 atattattgt ccttcatttt gttgttcagt ttaggttggt ggggaatgat gatatataac
     6901 aaaaatcctc atcacgtatt cgatctgcta tccgtataaa caggtatcac tgtactagca
     6961 tttgggagct actttttctt attgggaaaa gcagctcgcg gatggcctag cagacaaact
     7021 tttattcgaa atacttcatc catattaacg atgctagaaa tgatccgtac gattgatgat
     7081 ccgagtgtag cgtatgcgtt tgttgatgaa ggctgttatg gagaaaaggg cttagacagc
     7141 gtgagatcgg gtatgaaaaa agaggctatt cttttttatc tagactctgt tggggcagat
     7201 acaccgctac agttttcggg aaattatttt tcaaataaag aacagtggct gaaacaagtt
     7261 gataagttga aagaaaaaaa cgtcaattat atttttagtg caagaaaaaa gcaagcgcag
     7321 ttcttctatt tgaccaaaac agatttacga gggaaaacat ttaattggca aaatgccaat
     7381 cagattattg ctctttttcg ataagtaaaa agtgcaaaac aaggagtgag aagactaatg
     7441 ttggaaatca tgatcgttac acatggtaag ttgagcgaag gactgaaaga tgcggcggaa
     7501 gtaattgtcg ggacatcgag ccatattgaa acaatgtgct tagagtctgg ggaggacatc
     7561 caaacattcg gagagaaggt caaagaaaaa ttaactatga tcaacacagc agaacccatg
     7621 ctagtatttg ttgatctaat tagcgcaagt ccgtacaatc aagcgctctt ggcagtcaat
     7681 gaactgactg aagaaaagaa agcagccact tatgtcatag ggggcgtgaa tctgccaatg
     7741 ttgttagaag caatcaatca tcagatgctt cacacaccga tagaagaagc ggtggaacaa
     7801 attgtcaaac aaggaaaaga taatttaact gtttggcatg cttcagcgga agaaaaaaaa
     7861 ttagatgagg acgattttta gaaggaaggc tgaaaagatg aagtggggat ttagatggta
     7921 tggtgaaaaa ggggattcga tcccattaaa atatgttcgc caaataccgg gaataaatgg
     7981 gataattgga actttgctga ctaaaatgcc tggagatgtt tgggagattt cagaaattga
     8041 ggagttgaaa gcatctgttg agagccaagg actggaactg cttggaattg aaagtgtagc
     8101 gatccacgat gcaatcaagg cagggacaga tgaacgagat tactatattg ataactatat
     8161 acgaacaatc aaaaacttgt ctcgatgtgg ggttcgattg atttgttata gcttcaaacc
     8221 aatttttgga tgggcgaaaa ctgatttgtt taatgaaaac aacgatggaa gctattctct
     8281 tttatacgat cagaaaatcg tcgatcagat ggagccagga gaaatgtatc aattgataca
     8341 cagccagtca aagggattca aattgccggg ttgggaagaa gaacggttga aaaaattcgc
     8401 tcagctggaa aaactgtatg aaggaatgac cgaagaagaa ttatttgaaa atctgactta
     8461 ttttttagaa aaagtgattc cagtgtgcga aaaagcagat gtaaaaatgg ctatccatcc
     8521 agatgatccg ccatgggaac tttttggttt tcctagagtg acgaaaaatc ttggcgactt
     8581 gaagaaaatt ctaaatgcag tagattctcc atataatgga ctaacgctgt gcacaggatc
     8641 tttaggggca aatccggaaa acgatttagt tgaaatcatc catgaggtag gttcgcgcat
     8701 ccattttgtc cacttcagaa acgtggagtt tttaggagaa agaaagttca aagaaacggc
     8761 acatccctct acagaaggct cccttgatat gtatcatatt atgaaagcgt tggtgcaaga
     8821 agggttcgac ggtcctatac gccctgatca tggtagaacc gtgtggggtg aagtggctat
     8881 gcctggatat ggcctgtatg atcgtgcaat gggactcact tacatgcaag gtctatatga
     8941 ggcgataagt aaggaaaaac cactgggaga gcattatgaa taaaatcaag ctcttcatct
     9001 ttgatatgga tggcctttta ttagaaactg gacgtttagc ttatcgtgct tatgtaaaat
     9061 cagcacaaaa gtatgattat gaaatgcgta aggaagtcta ttatttacta actggccaaa
     9121 cagaaatggc gataagagaa caaatgggca ttttgtacgg agaagatgtt ccatatatca
     9181 aatggcgaga agcaatcaat caatataaag aaaaaatcgt gaaagaagat aagagagtat
     9241 atacgaaaaa aggagcagaa gaaattttat cttttgcaaa agaaagagga atccatacaa
     9301 tcgtggcttc gtctaataca cgggtaaaag tagaaatgta tttaaaaatg gaaaatctat
     9361 atgccttgtt tgatcaaatc atttcagggg atgatgtaaa aaaaggaaag ccggaaccag
     9421 agatcttttt gaaagcttgt tcaaaaatga atattcctcc aagtgaagca cttgtatttg
     9481 aagactcgat tgcagggatc gaagcagcaa ggcgagcggg cattttgtct tttctcatca
     9541 aagatcattt gatagggttg cccgatcata atgggaagca taagttgaaa gtagatgtaa
     9601 gtttatatga atccaataaa gcagactatg aattttatga cctgcatcaa gcaaaacgat
     9661 ttttagaaag taaagggttg tatctctaat aaagaggact attttctagt cctctttatt
     9721 tattgtcctg cacgactgag ggaacagatg aaaaagaagt aattttttat tttgaagtat
     9781 ctaccttatt tgtagtgaac aatttagaac aaacacaaaa cgcatctact gttatctacc
     9841 agtagatgcg tttaaagaga agaacgagaa tcgtccatat gagggtttcc actccttatg
     9901 cagatttttt taattcttgc actgcttgtt cgatcgtaac acctgtcgct acatgattgg
     9961 tattttcttt gtcaaaaacg acaaatagat tcaaatctgt atccaaggtt actcgatatt
    10021 gtatatcttt gttatagaat gtcatagcca ttctcctttc tttaaatact tgctgaaagg
    10081 caacgaacgc gttgataacg aaattccatt tataagtata ccaccaattg aaaggttttc
    10141 atagttaaga aattttaaag tcaaaagttg cagataaaag caaataaaca agaaaacaaa
    10201 aagtgaatca atcgcggtta ttcaactttt tcttcgattc gaagacaata gaagacaatg
    10261 aattttatat ttcattgcat tatccttgtg ttattagaaa aagcatgata tattaaatga
    10321 gtaatctatt ttgaaacgta atttgagcga tatatctaca tagataaaac tccttttgcc
    10381 tatcaaatat ttattgcaac gaaaaaacgt acattgatac gtatcaggag gaatttattt
    10441 atgaataacg gtacagtaaa atggttcaac gcagacaaag gttttggctt tatcactggt
    10501 gaagatggaa atgatgtatt tgcacatttt tcagctatcc aaggtgacgg cttcaaaact
    10561 ttagaagaag gccaagcagt gtcttacgat gttgaagatg gtcaacgtgg ccctcaagca
    10621 acaaacattg ttaaagctta ataaaaattg acttttaacc gtcttttcga aagaaaagac
    10681 ggtttttttg tacgaaaaaa tt
//
LOCUS       DAXLPY010000078        10495 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.078, whole genome shotgun sequence.
ACCESSION   DAXLPY010000078 DAXLPY010000000
VERSION     DAXLPY010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.078"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(1..459)
                     /locus_tag="ACF3UF_002283"
                     /pseudo
     CDS             complement(1..459)
                     /locus_tag="ACF3UF_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
     gene            complement(711..1070)
                     /gene="rplT"
                     /locus_tag="ACF3UF_002284"
     CDS             complement(711..1070)
                     /gene="rplT"
                     /locus_tag="ACF3UF_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFD3672363.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1123..1323)
                     /gene="rpmI"
                     /locus_tag="ACF3UF_002285"
     CDS             complement(1123..1323)
                     /gene="rpmI"
                     /locus_tag="ACF3UF_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFD3672364.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1395..1919)
                     /gene="infC"
                     /locus_tag="ACF3UF_002286"
     CDS             complement(1395..1919)
                     /gene="infC"
                     /locus_tag="ACF3UF_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFD3672365.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1963..2088)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2239..2871
                     /locus_tag="ACF3UF_002287"
     CDS             2239..2871
                     /locus_tag="ACF3UF_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFD3672366.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2873..3778)
                     /locus_tag="ACF3UF_002288"
     CDS             complement(2873..3778)
                     /locus_tag="ACF3UF_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3672367.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3863..4522)
                     /locus_tag="ACF3UF_002289"
     CDS             complement(3863..4522)
                     /locus_tag="ACF3UF_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFD3672368.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            4838..5782
                     /gene="mvk"
                     /locus_tag="ACF3UF_002290"
     CDS             4838..5782
                     /gene="mvk"
                     /locus_tag="ACF3UF_002290"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFD3672369.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5775..6752
                     /gene="mvaD"
                     /locus_tag="ACF3UF_002291"
     CDS             5775..6752
                     /gene="mvaD"
                     /locus_tag="ACF3UF_002291"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFD3672370.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6765..7850
                     /locus_tag="ACF3UF_002292"
     CDS             6765..7850
                     /locus_tag="ACF3UF_002292"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFD3672371.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7847..8911
                     /gene="fni"
                     /locus_tag="ACF3UF_002293"
     CDS             7847..8911
                     /gene="fni"
                     /locus_tag="ACF3UF_002293"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFD3672372.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9160..9963)
                     /locus_tag="ACF3UF_002294"
     CDS             complement(9160..9963)
                     /locus_tag="ACF3UF_002294"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFD3672373.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9983..10306)
                     /locus_tag="ACF3UF_002295"
                     /pseudo
     CDS             complement(9983..10306)
                     /locus_tag="ACF3UF_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
     gene            complement(10339..10476)
                     /locus_tag="ACF3UF_002296"
                     /pseudo
     CDS             complement(10339..10476)
                     /locus_tag="ACF3UF_002296"
                     /inference="COORDINATES: protein motif:HMM:NF018513.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
BASE COUNT         3105 a         2220 c         2008 g         3162 t
ORIGIN      
        1 atacctaatg acatcaagat cggcaacaca ataactgcaa tagaaatcac tggtccgatt
       61 cctgtcatcg acatgaatat aacagcggtt acaatacata gtaagctcat cgtgattctt
      121 ggcttgtccc ctccaagttc aactaccttt cgaatcaggg tagctgcgat tccgctatct
      181 actagaacac gcccgaaaaa ggcaccaaag aagacattta ccaagatcga tttggcgtac
      241 tcagctggcc ccgtcgtata gatatgcgtc aacacatcaa ttactccttg cccttccatc
      301 gccgagtttg gtgaaaacgt gtttccgact agcgctaatc ccatccatac agtagccatg
      361 atgacaaaag ccgaccatca agttgtagcc ttttacacag taccagacca tgaaaaagaa
      421 tgagataact aacaaaatac caataataat atcactcatg ttattcctcc gtccattttg
      481 tttttctgat aagcaaacta atatatcagt caaactcatt ctaacttatg tagttagcgc
      541 tttcattaaa ggatgaccat aaatgttcag ttttcaatta aaaaacctta attatgttat
      601 tttagactta tacgttattg tcctgtttca tttgatggag gattgtaaat aaaaaaagag
      661 gaaagaacat aacttttcgt tatcttcttt cctctttata attgtttagc ttatttagcc
      721 aaagcttctt ttgcttggtc agccaatgca gtaaatgctg ctgcatcgtt aacagccaag
      781 tcagctaaca ttttacggtt gatgtcgatt tcagcaactt tcaaaccgtg cattaatttt
      841 gagtagctca agccattcat acgagctgct gcgttgatac gagcaatcca caatttacgg
      901 aagtcgcgtt tcttttgacg acgatcgcga tatgcgtagt tgtatgaatt cattacttgt
      961 tcttttgctg ttttaaataa agtgtgtttt gaaccgtagt aaccttttgc taattttagc
     1021 actcttttac gacgtttacg agttactgtt ccacctttaa cacgtgccat gtataattcc
     1081 tcctaataaa aataaatctt cagattctgt tatttgtact tcttatttca tttttgctag
     1141 ttgttggcga atacgtttga agtcgccact agaaaccatg cttgctttac gcaattgacg
     1201 gcgttgtttt tttgttttgc cgtggaaacg gtgacttgta aacgcgcgga agcgtttcaa
     1261 tccgccttta ccagtacgtt tgaaacgttt tgctgatccg cggtgtgttt tttgttttgg
     1321 catgactata tttcctcctc aaaatctttc gttatccgac tatcggctgt ccaacagcca
     1381 gttagtcatt caaattactt actgtcgttt ttcggtgcca gcgtcaagaa catgctgcgt
     1441 ccgtccattt tcgctttttg ttccactgtt gcaatatccg cagtttcttc agctaagcga
     1501 ttcaagactt tttgaccaat ttctttatgg gtaatggcac ggcctttgaa acggatagaa
     1561 gctttcactt tatcgccctt ttccaagaac ttacgtgcat tacgaagttt tgtattgaag
     1621 tcattcaagt cgatcgtagg acttaagcga acttctttta cattgatcac tttttgtttt
     1681 ttacgcgctt cgcggtcttt cttttgttgt tcgaaacggt atttaccgta gtccatgatt
     1741 cgcgcaactg gtggtttcgc accaggggca actaacacaa gatccaagtt tgcttgttct
     1801 gcaatattca atgcttctgc ttttgtctta actcctaatt gctcaccatc tgaaccgatc
     1861 aatcgtaact ctcgtgcacg aatgccgtcg ttaaccatca tatcctttgc tatggtcatt
     1921 cacctccaaa tattatgaga gaaagaaaag cttaccgaat aaacggcaat aaaaaaacga
     1981 gttctcttac agaacccgcg cgtacttcac ctaatagaac cagtgaaaac tatctagccc
     2041 agtgacatta tcaactaagg cgagaagcgg gtgcttctgc ttttatttct caaccattat
     2101 agtatagcaa aaactaatct ttttgtcaat gtttttcata cagtttgtct tccttttctg
     2161 aaaatgatta gattagcagg ctttctagca gtgattcccg cttctttgct atactaaaga
     2221 aaaacgaggt gaacccacat gaaaaaaatc gaacctattc caccttctct tcctcttctt
     2281 acaaagggag agttttattt agaagatgag gagatcttct ctggtcttct gatcaacgga
     2341 ggtaaccaaa gctatctcga tgccaaaaat atggtattaa gagagagtca tatccaaaaa
     2401 cttacgatgc aaaaaacagg tttacgtcat tttgaatgca gtaatgtcat ttttgaaaaa
     2461 tgtgattttt ccaatctgga gtggattggt ggcagtttcc accaagtcgt gtttcatcaa
     2521 tgtaaattaa caggtacgaa ttttgccgaa agttatcttc gagactgtac tttcactgat
     2581 tgtattgctt cgatggcttc ctttagtagt acaaacttga aagctgtctc cttcgatcat
     2641 tgtcaattag aagacagcga attttatgag gtcacttgga aaaacctttt tttgtctgac
     2701 aatcagttaa ccggttcgaa ctggtttcga acttctctga agggattaga ctttacgact
     2761 aatttcttca caacaatcgc tttatctcaa gattctttgg cgggactaat cgtcaatcaa
     2821 gagcaagcac ttgtgatcgc ccaagccctt ggtttgcaga tcaaagacta gatcaacgaa
     2881 tccgccgcca cagtgcaata agcatccaaa tagataagac caaactgatg atcaaggcga
     2941 tttcccatcc gaaaacggaa tgggtaaagg gtaactggag attcattccg aagaatcctg
     3001 tcacaatagt tggaacggtc aagatcagcg accagaccgt caaaaatttc atcgtgtcat
     3061 tcaagttgtt attcagcaaa ttattataag tgccagagag ctggtctaaa atctgcgaag
     3121 ctaagttcgt catttcaact gcttgtcgtg cttcgatcag tgcatcgtcc aactcttctt
     3181 tttccttttc tgacaacttg cgataaatag ccagtgcctt gatttgttct aaaagtacta
     3241 cattttgttt tgttcctgta actaagtaaa ccaaaccgat ctctaaatct gaaagttgca
     3301 gcagattctt gttcgttgtt ttttctctta atttcagatt aagccgctga cgttcactat
     3361 tcacttcctc gattaaagga aaaaaggaat cagaaatcaa aaacaatgta cgaaacaata
     3421 aactgtatac actcatgtct ggcatccgtt ccaaaagcga tcgaattagt cgaatcacgt
     3481 actcggtatt cggcgtggta aatgtaaaca aaccgtcttc ttttaaaata aaagcgatag
     3541 gactagtttc ataatgatta tcgacttttt gctggtgcgg aacatttgat acaagcagta
     3601 acgcttcatc aaaagaatcg tactctacgc gcgcccgttc atttttatct agagaataag
     3661 tcagcatctc gtcactaatg ccatattctt cttttaagtt tttaacagct agcacatcgt
     3721 tttgctgtac attgatccaa aaattacggt cttgattaaa atagtgtttt tcccgcatac
     3781 tctatcctcc tgacatttgt ttccagtata aagaaaaaag tcgctcaaat aaaggtttac
     3841 cctttatttg agcaactgta aatcaaatgg atactttggt ttggcgaatc tctgctaatt
     3901 tttcttcgat cattttcaag acttcttctt ttgcttgagg atcttccaca aaattatagc
     3961 ggtctccatc gatttggatt tttggacttt ctttgtattc ttcataccat tgatcataac
     4021 gtctgttcaa ttctttgtaa taatcgtata gacttgggtc aaaggacaat tgttcatacg
     4081 aacgaccacg tttttcgata cgctctaaca tcgtatcaaa agatacacga atatgaacta
     4141 ataaatccgg atgtttttta tgggcagcat agggaagttc ttccatcatg ttttccagca
     4201 gttcatcata cacacaaact tctgtttctg ttgctcttcc tagatctgca tttagatgga
     4261 aaagcagtga atcttcataa atcgaacggt ccaatacatt attgtcatct ttcattgctt
     4321 gtttgatgct tgcaaaacgt ttattcaaaa aataaatttg cagcaaaaaa gcatactgtt
     4381 cagggtttgc ataaaataag ggcaagactt cattatcatc aatcgattca taaaatgcct
     4441 gactatcaaa gtgttcagcc atcatttctg ttaaacttga ttttccggca ccaattgtac
     4501 ctgctaaaac gatcacgctc atttacctcc agctcacttc atcactaaat attgtgttta
     4561 actccaacct tttttaaata tacccccaat atctagtagt gtcaattgta ttttttctag
     4621 tcaaagaaga aaaaaagtca aaaaattctt aagaaaaaag tgttttttct ttagaaaacg
     4681 tattcttagt tttacttctg agatggtttt agtaaaataa aggaggaatg ttttttgaga
     4741 cccttagtgg acaaaaaaat tcgtgaagca gcgcaactcg ttttgggcgc tttatttttt
     4801 gcttaaaaat cacttttacg tgagaaggag ttagattatg gcaaactatg gccaaggaga
     4861 atcaagcgga aagatcatat tgatgggcga gcacgcggtt gtttatggag aaccagcgat
     4921 tgcctttcct ttctatgcaa caaaagtcac cgcattcctt gaagagctgg atgcaatgga
     4981 cgatcaactg gtttcttcct actattcagg aaatttagcc gaagctcctc atgcattaaa
     5041 aaatatcaaa aaattattca ttcacttaaa aaaacagcat gacatccaaa aaaacttgca
     5101 actgaccatt gaaagcacga ttcctgctga acgtggaatg ggatcaagcg ctgcagtcgc
     5161 cacagcagtc actcgtgctt tttatgatta cttagcattt cctttgtctc gtgaaatact
     5221 attagaaaat gtccagcttt cggaaaaaat cgcccacggt aatcctagtg gaatcgatgc
     5281 agccgctact agcagcttgc agccgattta ttttacaaaa gggcatcctt ttgactactt
     5341 ttctttgaac atcgatgctt ttttgattgt cgctgataca ggaatcaaag gacaaacaag
     5401 agaagccgtc aaagatgtcg ctcacctctt tgaaacccag cctcatgaaa ctggacaaat
     5461 gatccaaaaa ttaggatact tgacgaagca agcaaaacaa gcaatcattg agaattcacc
     5521 agaaacgttg gcacagacaa tggatgaatc acagtcactt ctggaaaagc tgacaatcag
     5581 caatgatttt cttaatctat tgatccaaac agcaaaagat accggggcat tgggtgccaa
     5641 attaactggc ggtggacgcg gtggctgtat gattgcatta gcacaaacaa aaacaaaagc
     5701 ccaagaaatc agtcaagcac ttgaagatgc gggtgctgct gaaacttgga tacaaggatt
     5761 aggagtacat acctatgttt aaaggcaaag cacgcgcata taccaacatt gctctaatca
     5821 aatattgggg taagaaaaat gaagaactca tccttccaat gaacaacagc ctttcgttaa
     5881 cattggatgc attttataca gagacagaag tcatcttttc tgatagctat atggtagatg
     5941 aattttatct agatggcacc ttacaagacg aaaaagcaac aaaaaaagtc agtcagtttc
     6001 ttgacctttt tcgtaaagaa gccggcctct cactaaaagc ttcagtaatc agtcagaatt
     6061 tcgttcctac cgcagctgga ttagcctcct ctgccagcgg gctagctgct ttagcaggag
     6121 cttgcaatac tgctcttaag cttggattag acgatctctc tctttcaaga tttgctcgac
     6181 gcgggtctgg ttcagcttgc cgaagtattt tcggtggttt cgttgaatgg gaaaaaggcc
     6241 atgacgactt aagttcttac gctaagccag tcccttccga ttctttcgaa gacgatttag
     6301 caatggtttt cgttttgatc aacgaccaga aaaaagaagt gtccagcaga aatgggatgc
     6361 gtcgaacagt cgaaacatcc agtttttatc aaggctggtt agattccgtt gaaggggatc
     6421 tatatcaatt gaaacaagca atcaaaacaa aagatttcca acttctcgga gaaacgatgg
     6481 aaagaaacgg actaaaaatg catggaacga ctttagctgc ccagcctcca ttcacttact
     6541 ggtctcctga cagcttaaaa gcgatggatg cggtgcggca attgagaaaa aaaggcattc
     6601 catgctactt tacgatggat gctggcccta atgtcaaagt tttagtggaa aacagccatt
     6661 tatctgaggt acaagaaaca tttaccaaat tatttagcaa agaacaagta attactgccc
     6721 atgctggtcc aggaattgcg attattgaat aaagggagat ttttatgatt gaagtatctg
     6781 caccaggcaa actctatatt gccggagaat atgcagttgt tgaaacagga catccagcag
     6841 ttatcgctgc agtcgatcaa ttcgtaacag tcactgtaga atccgcacga aaagtcggaa
     6901 gtatccaatc tgcacaatat agtgggatgc ctgtacgttg gacaagacgc aacggagaat
     6961 tagttttaga tattcgggaa aatccttttc attatatcct tgctgctatt cgtttgactg
     7021 aaaagtatgc acaagaaaaa aacattcttt tatcctttta tgatctgaaa gtaacaagtg
     7081 agttagacag ttcaaatggc cggaaatatg gattgggttc tagcggtgcc gtgaccgttg
     7141 caacggtcaa agccttgaat gttttttacg cgttgaattt atctcaattg gagattttca
     7201 agattgcagc actagccaat ttagcagttc aagataatgg ttcctgcggc gacatcgctg
     7261 ctagctgtta tggtggctgg atcgctttct caaccttcga ccatccttgg ctccaagaac
     7321 aagaaactca gcattctatc agtgagttac ttgccctgga ttggccaggt ctatccattg
     7381 agccattgat tgctcctgaa gatttacgtt tattgattgg ttggacgggt agccctgcct
     7441 ctacttctga tttggtcgat caagttcacc gttcgagaga agacaaaatg gtggcttatc
     7501 agcttttctt aaaaaacagt acagaatgtg tcaacgaaat gatcaaaggg tttaaagaaa
     7561 ataatgtaac gttgatccaa cagatgattc gaaaaaaccg acaattactg catgatttat
     7621 ctgcaatcac tggggtcgtc atcgaaacgc ctgctttgaa caaattgtgt aatttagctg
     7681 aacagtatga aggagccgca aaatcttctg gtgcaggtgg tggcgattgc ggaatcgtaa
     7741 ttgttgacca gaaatctggc atccttcctt taatgagtgc atgggaaaaa gcagaaatca
     7801 ctccactgcc gttacatgtc tatagcgatc aaagaaagga aaaccgatga atcgaaaaga
     7861 cgaacatgtt tcactagcta aagcctttca tgataaacaa aaaaacgaat ttgacttcgt
     7921 acggatcatc cataaccctt tgccgcaaat agcagtttct gatgtcgatc taagtacaca
     7981 ggcagttggg tttacactaa gcagcccatt ttatatcaat gcgatgactg gcggaagcga
     8041 aaaaacaaaa aaaatcaacc aagatcttgc aatcgtcgca agagaagcag atttgatgat
     8101 tgccactggt tcagtcagcg ctgccttgaa agacccttct ttagccgata cttatacgat
     8161 tatgcgacaa gaatatcctc acgggaaaat cattgccaac atcggtgcag ggacttctgt
     8221 cgaaagagcc caagaagcta tccgattgtt tcacgcagat gccttacaga ttcatttgaa
     8281 tgcacctcaa gagttggtta tgcctgaggg agaccgtgat tttaccaatt ggaaagtact
     8341 tattcaagag actcaaacag ccattgacgt ccccctcatc gtaaaagaag tcggttttgg
     8401 catgacaaga gaaacgctca atgatctagc tgctttagga gttcatacag ttgatatcag
     8461 cggtcgaagc ggaacaagct tcacccagat cgaaaacgcc cgtcgctcca agcgggaact
     8521 gagttattta gctgactggg ggcaatcgac agtctcttca ttgcttgaag caaatgaagc
     8581 agacacttct atggaaatcc tagcctccgg aggtatccgc aatgcctatg acatatttaa
     8641 agccctttgt ctcggcgcaa atgcagtggg tacttcagga accgtactga cgcatctgat
     8701 gaatcacggc gtagaagaaa ctattatact gatgaagcaa tggcaagaag agcttcgtct
     8761 gctttatact atggtcggcg caacgaatac cgcggcccta caccaacaat cactgatctt
     8821 ttccggacca gtgaaggatt ggtgcgaagc aagagggatc gacttagtga agtatggaag
     8881 acgcacagaa aagagcgtgg gacaaaagta aagaacactt ttatcccacg ctctaaacac
     8941 gtataaacgg cggaagcaaa agcaactcct tcggaaataa gctgaaattc acaaaaattt
     9001 gaaaagcaat tttcgtgaat tccttcttat ttcttggagt taaacgcttc tgtcccagcc
     9061 tcttttttcg aataaatgat gtttaatcag ctgtccttcg gtattcgttc aagccgctga
     9121 tttcacaacc tctccactaa acggtgtact aaagctcttt taaggttgtt ttccgatata
     9181 ggcaagtatg cctccgtcca catacaagac atggccgtta acgaaatcag atgcgctaga
     9241 agccaagaag acagatggtc cagccaaatc gattggctcg ccccagcgtg ctgctggcgt
     9301 acgtccaacg ataaattgat cgaatggatg acgttcaccg ttttcttgtg tttcgcgtaa
     9361 tggagcagtt tgcggtgtag caatataacc tggtccaatt ccattacatt ggatattgta
     9421 ttgaccgtat tcagaagcga tgtttttcgt cagcattttt aatccgcctt ttgccgcagc
     9481 ataagcactg accgtttcgc gtcctaattc actcatcatg gagcagatat tgatgatttt
     9541 accgccgcct ttttcgatca tatcccgaat aactgctttt gaaacgatga atggggcatt
     9601 taaatccacg tcgattactt ggcggaagtc tgccgcatcc atttcgatca tcggtgtccg
     9661 tttgatgatc cctgcattgt tgactagaat atcaactgaa cctacatctt ctttgatctg
     9721 ttgaaccatc gcttgaaccg cttcttcatc ggtcacatcg cagacataac cttttgcatc
     9781 gatgcctgct tctttataat gcgctatacc ttcatcaact gattcttgat tcaagttatt
     9841 aaatacgatt tttgctcctg ctgtagctaa agagcgtgca atctcaaatc caataccata
     9901 gacagcaccg gtgactaatg ctacttttcc atctaaacga aacatatcca tactaaattc
     9961 catcattttc tctcccttat gcttatttta attgatccat ttgcaccata tccatgtctg
    10021 tataggtgat attttctccg cacattgccc agatgaatga gtaattgctt gtacctacac
    10081 ctgaatggat cgaccagctt ggcgaaataa tggcttgttc attgtctacg actaaatgtt
    10141 ttgtttcatc tggtttgccc atcatatgga acacacgtgt atcttcattg gcataatcaa
    10201 aatagacata agcttccata cgacgttcat gtgtatgaca aggcatcgta ttccaagcac
    10261 ttcctggttc taaaatcgta taacccattt ataaatgaca gctatcgctg aagcttctac
    10321 tgctgtaaat atccccgtca agataccacc gataatgatg acaatcaata gaaggctagg
    10381 aatcgcctct tttattattt ttccagcatg agccatctgt cctttttcga caacagggta
    10441 tttattcttt ttagcaacga tgaatgctac tagcatgatt cctagcgccc acaaa
//
LOCUS       DAXLPY010000079        10494 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.079, whole genome shotgun sequence.
ACCESSION   DAXLPY010000079 DAXLPY010000000
VERSION     DAXLPY010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.079"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            132..725
                     /locus_tag="ACF3UF_002297"
     CDS             132..725
                     /locus_tag="ACF3UF_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672374.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            747..2441
                     /locus_tag="ACF3UF_002298"
     CDS             747..2441
                     /locus_tag="ACF3UF_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFD3672375.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            3129..5006
                     /gene="ltrA"
                     /locus_tag="ACF3UF_002299"
     CDS             3129..5006
                     /gene="ltrA"
                     /locus_tag="ACF3UF_002299"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFD3672376.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            5137..5514
                     /locus_tag="ACF3UF_002300"
                     /pseudo
     CDS             5137..5514
                     /locus_tag="ACF3UF_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            5514..6719
                     /locus_tag="ACF3UF_002301"
     CDS             5514..6719
                     /locus_tag="ACF3UF_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3672377.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            6735..7379
                     /locus_tag="ACF3UF_002302"
     CDS             6735..7379
                     /locus_tag="ACF3UF_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672378.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            7390..8196
                     /locus_tag="ACF3UF_002303"
     CDS             7390..8196
                     /locus_tag="ACF3UF_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672379.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            8218..8448
                     /locus_tag="ACF3UF_002304"
     CDS             8218..8448
                     /locus_tag="ACF3UF_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672380.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            9005..9280
                     /locus_tag="ACF3UF_002305"
     CDS             9005..9280
                     /locus_tag="ACF3UF_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672381.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHELMDHRKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIE"
     gene            9322..9744
                     /locus_tag="ACF3UF_002306"
     CDS             9322..9744
                     /locus_tag="ACF3UF_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672382.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKPINESVHARVDPFDPTKFLKR"
     gene            9764..>10494
                     /gene="mobL"
                     /locus_tag="ACF3UF_002307"
     CDS             9764..>10494
                     /gene="mobL"
                     /locus_tag="ACF3UF_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HFD3672383.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNT"
BASE COUNT         3921 a         1662 c         2211 g         2700 t
ORIGIN      
        1 gaccctataa taaccctggt caacgccaaa tttttgcgat tatcgaatct attttcttta
       61 cggataagaa ccactatcat gcgttagatc ctaaccgaaa ttatcatggt acgtataagg
      121 aggatgaata aatgcgagtc aaaggacaaa attcagttga taagaaatcc attttgcagt
      181 ttggaaaacc agaagagcgc tctatcttgg acttatttcc atataaatcc tgtacagaag
      241 agggagtctt aattactaga gaagatcatt ttcagcgtta ttatcgtgtc gtttccactg
      301 acgtggaggg attaaatgaa caagagaaac tagaacgaat gaatcagttg accaccgtca
      361 tgcgtacgta tgtgccaaca attaagttag ttagtttgac cacagagacg gatctaacgg
      421 aacaaatcgt gcaaaagcgg cagttattag ataaaaatcg tatggaacag tcactaggaa
      481 gaaatctaca gcgattaaga aaatatgaaa agaaattagt agaggagatc caggaattaa
      541 aacgggcaga acaagaacgt cctgacttaa gcttcttttt cgttattgaa ggaaagacaa
      601 tcaaggattt acaaactaga aatcgtcagt taatgcgatc tagtggcatt ttagggttaa
      661 aaccactcta caaaaaagaa ttgattaaga ttctttatcg aatgaacaac atgaatgacg
      721 aataaaaaag atggaggaaa tgattcatgc tagatgtgat aaaaacagct ttttcaacgc
      781 aaagtaatca aaaggtgatt gatccattaa aacaacttgg taatcgtgaa atagagattt
      841 taaaatcaaa aggttatgat ttagatttct taaaacaagt gatgccacaa ggtgggttga
      901 attttgatga agaatatgtg acctatggaa atggttattc acgatgtgtg acagtttatc
      961 attacacaaa aaatcctact cttttttggt tggccaatct catgaacaat cctcatacag
     1021 tggccacact agatgttagc acagatgaaa agcaaaaagt gattgatcaa atcaaccgcg
     1081 cattagatga attaaatgat cgatcagata atgaacgaaa agcgactgac cgaaataaaa
     1141 gtgcggaaga atacctggaa ctagcggaat atgcccgaaa attgacttct aatggggaaa
     1201 tttctaaaca agtcaaagtg agagtacatg tttacggaaa tacgatccaa gaagtggatg
     1261 aacgggcgca ggaactgatc gaaaatctaa aagggatgga ttatcgtgcg gtgacttatc
     1321 tgcataaaac caaacgagat tggcaatcga tgtttaccat gttcgatgaa caagctgaat
     1381 ggtttggaaa tatcaaaggg caatcacttc catcgttaaa cattggcgga ggattcccgt
     1441 tccaccacca aacgctaaaa gatccaggag gcacacaata tggggaaacc atgacaggcg
     1501 gcccatttgt ctggaatgcc acgtataaaa atagtgtacg tttatctacc aataccttgc
     1561 ttctaggaat gatgggagct ggtaaatcga ccgttcttaa aatgatcgcg gaagcccatt
     1621 tagctgcagg agactttatt tggggctttg aaaagggaaa agactttatt cctttcttaa
     1681 aggaatataa cggtattatg gtgcgtttag acggatctga cggaatgatc aatcctttag
     1741 agatatttgc cacacggacg tatgatgaag catccagttt atatgacgat ggatcagtca
     1801 aagatttgaa gatcaatgaa gcagcgtcct atcaaacaca cttagacaaa gtggtctatc
     1861 aggtacagtt agtgagtcct cagctaaaag gaacgatgaa agcagaattt aagacctact
     1921 taaatcgttt ttatgaagag tatggaacag taccacgcgg ctttacttcc tcaaattcgc
     1981 gttcaaatac tgatacgcaa gtcacaggga aagatccaga agcttatccg acgttcaaag
     2041 aatttttagc ctttttagga caactggaac taccaggggc ttcccaagag aaaaagaatc
     2101 ggaaagaaga aatggagtct atcgtggaat ccttatgtga gacttatggc atgatttttg
     2161 atggtcatag tacgattcga caccttgacc aacaacagtt ggtctttttt gacattgact
     2221 ctattacagg cctagatcga ggggtacaac aatgtcagat gtacatggcc atgacgttga
     2281 tttggaatca ggcattgatt caaggacgaa gacaacgacg cttaattaaa gaaaaacaaa
     2341 tggaagaaca agacttcaaa cgcttcttgg cgatgattga tgagtgccat aatggtgcga
     2401 cctgttctgc agtgaaaagc tgtgggttgc aagtagtcta aaaactattg taataactct
     2461 tataacgaga agtcaaatga gtgggtaacg ccacaaaggg cttccactga tactccgaca
     2521 tgcaacaagt agtttatgca gaccaacgtt gtgtgaagct cggtgaagtc ggctgaagga
     2581 taccgtaagg taaaagaaat agtgaatacc acgaaagttc tctagaggta aagggtgtat
     2641 ccgataagtc gggtgtccaa aaaaacttaa tatggtgagt atgtacaaac gtactgacga
     2701 actagcgaat gtactgtccg aaaggcatag ctcctagaaa tgggagagac agtgagcaaa
     2761 aaatcactca ttgtgctaac ttgtggttga gtaaaagtcg ttgttatgaa agaccatgct
     2821 gcgttacagg cgtaggagaa gttagggggc aaaagctagc atctaagtta aggcatgtgg
     2881 atagatataa gggaacaggg gaagccatca acatggagag tgcatactcg atgaagtggt
     2941 agtaagaaat atgtgaatga caaataactt actttagtga tggtgaaagt agagtcacga
     3001 ctgatgaagg ttctgtaatg gaactggagg aacaggctcg attcgtctgt aaaagtcatg
     3061 aaacccgttc aaccatggga ttctcgtatg actaaaaagg tcacgagcca attggagcgt
     3121 gataaaccat gacaaaagaa acaagtccaa aagataggaa gttgcggcat gcagaatatt
     3181 atggcatgac ggaaatcttc gataagatat actccaaaag tttgaaggga gataatttca
     3241 agaatctaat gcagattatc atttctgata acaacattgt cctagcatat cgtaatatca
     3301 agagaaatca cggtagtgtg acaagaggag aagatggagt aacgattaaa gatattgaaa
     3361 atctcaaccg taatgaattc gtagaaattg ttaggaagcg attcgcacat tataaccctc
     3421 ggaaagtaag gcgtgtagaa attcctaaat ataatggtaa attaagaccg ttgggtattc
     3481 catcaatatg ggatagaatc gcgcagcaat gcatcttaca agtattagaa ccaatatgtg
     3541 aagcaaaatt caataatcac agctatggtt tccgcccaaa tagatcagca gaacacgcaa
     3601 tagcagattg tatggcccga atgaatcaaa gtcacatgga atatgtggta gatgtagata
     3661 tcaaaggttt cttcgacgaa gtcaatcata ctaaactcat gagacaaatc tggtctatgg
     3721 gtatacgaga caaacagctt ctcttaatca ttaggaaaat gttaagagca cccgtagtac
     3781 ttccaaatgg gaagttgata tacccaacaa aaggaacacc acaaggcgga atacttagcc
     3841 cattacttgc gaacatcaat ctcaacgaat ttgactggtg gatagcaaat cagtgggagg
     3901 aaaaagatgc caaagagcta aaacatcatt ttaggaaaaa tggagcttgg gataaaggta
     3961 atatctatca caagctcaga aagagtacaa ctctaaaaga aatataccta gtgagatacg
     4021 cagatgattt taaaattttc tgtagaaatt ataatgaagc gaaaaaagtt ttctatgcaa
     4081 ctaaaatgtg gttacaggag cgtctaaagt taccaatatc tgaagaaaag tcaaaaatca
     4141 caaatctttc aaaagaagaa agtgaatttt taggctttac gatgaaatta gtgaccaaag
     4201 gtaacaaaaa ggttgttaat acgcatatag gtacaaaagc acaaagcatg attaaagtga
     4261 aactaaaaaa acaaatcaaa cgaattcaaa aaagtcctaa tagcaaagat acctttatct
     4321 atattggagt ctataacagt atggttattg ggattcataa ttacttcaaa attgcgactc
     4381 attgtagtgt agcaatgcga aaaattgcaa gagaactcag accaagtttt gaaatacgac
     4441 tacgagaaca aggaatctca aaagaaggac aatacggaaa gtacgaagga tacaagcctt
     4501 acctacggtc aggacaaata cgatatataa gagggtttcc aatattacca gtagggtata
     4561 ttcaacacag acatccgatg tgtaaaaaaa gaaatattaa taaatacacc gaagaaggta
     4621 gggaagccat tcataagaag caacaaaccg tagaagaatg gaagatatcg tggttgtgta
     4681 gcaatccagt gcttagtaag agagcaacga ttgaatttgc ggacaatcga atttcaaaat
     4741 tcatcgctca aaagggaaga tgtgcagtaa caggtgagga gcttatctta tctgaaatgc
     4801 attgtcatca tattatccct tatcatgaaa gcaaaagtga tagctatgaa aacctagtga
     4861 ttgttactga ggaggttcat cgggtaatac acgctacaca aagtgaaacg attgaggaac
     4921 ttctaaaata tctaaaatta aatccaaaac aaaaagaaaa actcaatgag ttgagattaa
     4981 aagttggtaa cgaagaaata tcttaataaa tatttgtagg acgggaaaac agaatgtctt
     5041 ttatagacga gggaacgccg tatgcggtga aagtcgcacg tacggtgtgg actgggggaa
     5101 aagacggaga taatatcaaa ctcttaccta tcagtatcga ttaatccaga ttttattgaa
     5161 acggtaaatt atgtcacaaa ctttcaacga gaaatgcgta aagtagaagc aatgactgtt
     5221 ttagctacac aatccccaca agaaatggtg ccagaaaata tgtcttctga taacttctcg
     5281 aaactgaaga aagtctttga attttcttct acgaagatct ttatgcgtat ggatgaatct
     5341 attttacgtc atatagaagg attagtgggt aaatcaatga cgaactcaga attagaatcc
     5401 attcctcaac aaaatcaagg agacgctgtg atcaattttg gctcaaaaga aaccattcgt
     5461 gttcatttta gtccgaacaa acgtcaatta aaattgtttg atggaggaaa ataatggaaa
     5521 accaaaatga aagtttaatc aagcagtatg ttaagcgtcg tgcaaagcgg cgcttatttt
     5581 tgtggttgtt tggtacttct gcaggtttga ttactatttt gatcactgtg ttcgtgaccc
     5641 tatttctaat acttgcggcg ggctcgattg ataattcgga ttcagattca agcagtggtg
     5701 gcgaagcttt tacaggagaa tattcggaag gcttaccgat ttataaagaa atcaaaggaa
     5761 gaggcccttt ttctgatgag attgcgcaat atgccgtagg tgcagcagtg aaatataaat
     5821 tattaccaag tgtgatcctt tcgcaatacg gttacgaatc agcgtttggt acatcggcgt
     5881 ccgcaagaaa tgatctcaac tattttggga ttacttggtt tgatggttgt ctgtttccta
     5941 aaggaactgc acgaggaatt ggtggcattg aaggtggctg gtacatgaag tttcccaact
     6001 caaaagctgc attttcctat tacggcttta tggtagccac acaatccaat tttaatgctt
     6061 gtgtaggaaa taaaagccct ggcgcaagct tattgatctt aggacgaggc ggttatgccg
     6121 ctgcaggaat tacggaagat agtccgtatt atacaggttg tatgtcaatt atcacttcta
     6181 ataaattaac cgaatatgat gaattcgcca tcaaacattg gggtgaaggt ggcaataaca
     6241 acggcacgat tactggtgaa tggacgaatc cattccctgg cagcagttta gataaaagtt
     6301 ccttcagcgg tggtcaatta tttggaacga atccaggcgg tgaattccgt ccgaacggct
     6361 tccatgatgg attagatttt ggttcagttg atcatccagg aagtgagatt catgcggttc
     6421 atggcggaaa agtcgtgtac gttggcaatc ctggtatttc aggtttgggc gcgtgtgtga
     6481 tcgtgattaa ttacgatggc ttgaatatgg tgtatcaaga atttgcaaat agtacaggaa
     6541 attctcgagt gaaagtaggc gatcaagtga aagttggtca agtaattggg atacgagata
     6601 cagcacactt gcatttagga tttactcgaa tggattggcg tcaagcacaa ggacatgcat
     6661 tcattgatga tggtacatgg atcgatccgt taccattttt gaatagcagt aaaaaataga
     6721 tcaggagaaa aaatatggaa aataaaacgt taaaaatcgt cttaacagct gcaattagcg
     6781 ttagtttaat cggcaatatt gcgttgtttt ggcagctgaa agaggaacaa gcagcaaata
     6841 cctataaaat tgaagaagtg gctaaaaacg cgtctgagaa gctcaaaaaa aattcctctg
     6901 aggcacaggc gaagatcgac aagttaaatc aaaccatcaa tgagaaaaac caagaaatcg
     6961 atcagctgaa gcaacaagat ggcacaaaag caaaagagga agtaactgaa gcacaaagaa
     7021 agacggcaga agagttcggt caattggcca ttgataaatc attaagcaga aatgaattaa
     7081 cggaaaaact aaaagatgtc gcaacccaag aagtgatcga caaattaagt cctacagacg
     7141 atgatcacca acatgatgat tacggaagtt actcctttac attaggtgac gtgcaaactt
     7201 acgctcaaac aagcagtgta aaagaggaac aaaattttgt cgtatttgtt gattatacaa
     7261 tcggcaatcc gcaattcaaa gatgtcaaac cacaaaaaat aaaaggtgga ttaactgtca
     7321 ctgaaaaaca agtagatggt caatggaaag tcatagactt tagttatttc actcgttagg
     7381 aggaagaaaa tgagtaagaa aaaaggagaa agacaacgtt tcaaaaaacg aaaaagttat
     7441 cttagatggc tgggaatctt tatgattctc ggctttttga ttcttgctag tccgatttat
     7501 acgaatcaga aggtagatat accagatgag gtaagcacga acgccttttt aaacacgaaa
     7561 gagctgacaa tggtttcaaa agaaaaagga gcgaaccagc aattagtttt tgaatttgcg
     7621 atcgatgatg aagatcaaag cttgttaaaa gaactggcta atcttaatta tcgcgtagaa
     7681 gtaaagacag ctaaagggga ttatcaagca atacgagcca aagtgattaa ggtgtctgat
     7741 gattattttg cagtgaagct aacgcatgta ccagaagaat atatcgccat gcgtttaacc
     7801 attattcctg aaaaaattga tccaaaagtg gatatgcaag aaccacaaga tctgatttat
     7861 tacgtgcacg aagataaggt taaagatcaa gtgaaagatg aagattatga acaacacgcg
     7921 atcaattaca aagtgaaagg atacaagaaa gaacaaaaag cagctcaaaa acaaatggaa
     7981 tctttccaag caaccattga tttgaatgaa gaattagtga agaagctaaa agatcaattg
     8041 ccttatcaag tcgcagatga tcaggaaaat actgaaaaca agattaatag ctaccagcaa
     8101 gaaattgaaa catcgaaaac gcaactgaaa gatcaagaag agatcattca aaaacttcaa
     8161 gaaaaaattg atcgtatgac aaaagaaaag atttagaagg acaggtggag tgaaaaaatg
     8221 aagcgaacaa acttggctga caaagatact ttcgctgagc agaaagtatt gattaaagcc
     8281 tatctcaaag ttgtaaaagc taaagaaata tgtcgagaag tgaatttatc taacacaaca
     8341 atatctgagt tgaagaatgg tcgaaagaat ttagatactt taaaattcag atcatttgaa
     8401 gctctatatg tagctgctaa aaaatatttt acagctgata acaaataaaa aacaggagta
     8461 ttttatgtga aaaaagtata taaaaaatgc ttatgaatca gctatatcac cttaaccatt
     8521 tgttaatgag atgggagaaa acattaacca cgattctaac gcaaacatca agcacataaa
     8581 acatttaaca ctcctccttt ctggctgaag atttcaacca aacaggaaga cagcgtatca
     8641 attatagcat acactttttc ttaaattcat ttttcatatg acaaaatatt tccttctaat
     8701 cgacaaagtt agaaggattt tttattgtct aaatacacaa ataaccttaa tttttaaaga
     8761 gcataaggaa acgtgtaccc actttcaaaa taaagtgggt agataggctg tgcctatcac
     8821 gtttctgaaa aaaataaatg accccaaaat tttcaattta tgtgtaggtt tatgggtagc
     8881 aaaaatatga atgtgggcag caaaaagttc atttgtgggt agtaaaattc aaatgtgtgt
     8941 agcaatgtgt gtagctacac acattgctac acacgctata acatatagtg aaaaggagat
     9001 atttatggaa gtaaaaataa gagatattga tgaaaaaacg attcaaagaa ttgaccgaag
     9061 atgtattgaa ttaagtgaac gcaccgggac taaatggagc cgaaatcgat acctaaaagt
     9121 tttgattgaa aatgattttg accatgaact tatggatcat agaaaagatc aatttgatcg
     9181 gttgttagaa aaatttgtgg atattcaaac ttataatacg aaaattttag aagaatatat
     9241 tgcaacaaat aatcaattaa tcgccttgtt aattgaataa taaaaatagt attgtgaatt
     9301 tataaaagga ggaaatcaat tttggcaaaa gcaacaagaa aacatgtata tctttacgat
     9361 atgcatatcg aagtacttga tgaaataatt tctactcatg aagatatatc taattatagt
     9421 gaagcagtca gacatttgtg tatgatgtat gatccaaaaa tcgaagaaaa aataaatcca
     9481 attcaaatta aattgaatgc aatgggaaaa gaaatttcta tattaaccga aatggtttca
     9541 gagtttgcgg atcttcattt gaaagataca ggaatactaa ttggtacaaa ttcaactgtc
     9601 tatcaagaag caaaagagcg tgtggaaggg aaaataaaag cgaatcaaac gaaaaagtat
     9661 tctcctaaga tcaagaaacc aataaatgaa tctgttcatg ccagagtaga cccgtttgat
     9721 ccaacaaagt ttttaaaaag ataaaaagta gaaggggaac atgatgaata aatcgcctgc
     9781 agtcattctc acttgtcaat ttaccttgcc caataaaaaa tctttttcaa catacattga
     9841 ttatatgaca agagaaaaag cgctggaaga aaaggaacga cgcacgccgg acgaagaaca
     9901 ggaactgcaa cgaatcaaga atgctttaga ggatttttat attcctgaag gagaaacttt
     9961 ttcggagagt aagacagata aagaattcag tgaaacgtcg aatgaagctc aatcgttgat
    10021 ggaacatgga atcaattttg acaagttaga ggaacaagat tttaccaaat atctttctta
    10081 tatgacccgt cactatgcgt tagaacaaaa gaaagaactg acgcaaaggg aacaaaaaga
    10141 ataccaacgg ttgaaccaag caatgaaaaa atatcaaaca gagccacata aaaaagcttc
    10201 aggaaatctt cctggagttt tttctatggc ttcagacgaa gtgaaaggaa gtgatctgaa
    10261 ggagatcaaa caaatcttcc aaagagggca acaaaaaggc tcaatcattt atcaagatgt
    10321 tgtctctcac gacaattcgt atcttgaaaa aatgggcttg tacgatccca aaacagatac
    10381 cttagatgaa gaaggattaa aagcagctgg aagaaaaatg atggagacat tattcgagaa
    10441 agaacaattg aatgaaacag gttactggat ggcaacgatt caccgtaaca ctaa
//
LOCUS       DAXLPY010000080        10412 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.080, whole genome shotgun sequence.
ACCESSION   DAXLPY010000080 DAXLPY010000000
VERSION     DAXLPY010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.080"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            112..852
                     /locus_tag="ACF3UF_002308"
     CDS             112..852
                     /locus_tag="ACF3UF_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672384.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(1143..1811)
                     /locus_tag="ACF3UF_002309"
     CDS             complement(1143..1811)
                     /locus_tag="ACF3UF_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3672385.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            1945..2232
                     /locus_tag="ACF3UF_002310"
     CDS             1945..2232
                     /locus_tag="ACF3UF_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672386.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            2648..4186
                     /locus_tag="ACF3UF_002311"
     CDS             2648..4186
                     /locus_tag="ACF3UF_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFD3672387.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTSTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            4183..5148
                     /locus_tag="ACF3UF_002312"
     CDS             4183..5148
                     /locus_tag="ACF3UF_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3672388.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            5135..6457
                     /locus_tag="ACF3UF_002313"
     CDS             5135..6457
                     /locus_tag="ACF3UF_002313"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3672389.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      6520..6624
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6698..7441
                     /locus_tag="ACF3UF_002314"
     CDS             6698..7441
                     /locus_tag="ACF3UF_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3672390.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            7456..8448
                     /locus_tag="ACF3UF_002315"
     CDS             7456..8448
                     /locus_tag="ACF3UF_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3672391.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            8460..9197
                     /locus_tag="ACF3UF_002316"
     CDS             8460..9197
                     /locus_tag="ACF3UF_002316"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3672392.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            9187..9909
                     /locus_tag="ACF3UF_002317"
     CDS             9187..9909
                     /locus_tag="ACF3UF_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFD3672393.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(9993..>10412)
                     /locus_tag="ACF3UF_002318"
     CDS             complement(9993..>10412)
                     /locus_tag="ACF3UF_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFD3672394.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3457 a         1792 c         2171 g         2992 t
ORIGIN      
        1 tatttatgaa attcatcgct attttcttaa aataatcagc gcattgctac tgaaaacaat
       61 gaatctgtgc tattattgag aaaagttcca tttttgagaa ggatggtttg aatgaaagaa
      121 atcagacgaa aacatttccg ttttcctgcg tacgatgatg agttaggcgt aaaattaacc
      181 aacgacaaga agcgagtatt atttgacgga caagaagatc ttttgactga acagaatcag
      241 tccccgtttg aacagatgaa agaatttcat ttcacgaaca cgaacaccga gaaaatccgt
      301 cgcaagcgtc gtgcaacaaa tggattgaag tcagctccgc gtaaggaaaa tttggaaaag
      361 cataaaggaa aattaccgga ttataccggc cattaccaat cagaaatcac atcgacagga
      421 cgaaaaaaac tttttggtga ttcctctcgt tctgtcagac aaagtgaaac aaggacagag
      481 tccaagcata ctacacgaaa cgcatctgtt gacacgaagg tgcgggagcg ttcttatttt
      541 gttcctaaat atgtacccgc atcgattatc ccagacccta gagaaagcaa aatttctgag
      601 gatcatttaa tcgaatcgat gaaaaaaacg gatgactctt atctgttgtt cgatacagaa
      661 ccgacgccgt atcaagaaaa aagaaatggt gagccgtctg tacgaacatt caatcgaaca
      721 aaaacgttag aggaaacaaa gcagtcagaa gaaaaaaaat cgaaaaaaag ccatggtatc
      781 ttagaacgct cattacaagg attgatcgat gatcaaggaa actctttggg agaaaatagc
      841 tattttaaat aagtgatata caaatttata ttcggctaca gttggaaagg aaacgctgcg
      901 gcgtttcctt attttatact ctatccgaaa gtttatatcg tatcctcaaa tttttttgag
      961 tttaagcgaa ttttttctcc caataagtaa gaaaataatg gcaaaataaa aaaacaaact
     1021 attttcgcag atcgtttgca aaaatagttt atttttttat aaagaagatt ttactgaata
     1081 atatcatttt agtttacata atgatatttc tgtaaattaa ataaagtagt gaaaaataag
     1141 aatcagtgct ctaactgttc aagaggatca agtggttcaa atgtttctgt agtctgtttt
     1201 gcttccaatt ggggcaaaac agatccaatt tccagatact tcactttatt caatgtataa
     1261 gatagaatag aacagctaag taatgtatac agaaaatgtg tgagatccaa ataaagcaag
     1321 gagacaacta aaataccaaa agtaatcaag aaaagacttt tgccaatctt aatatgaaaa
     1381 tatttttcaa tggcttgata aatgatatct gttccgcctg tgcttccgcc gaatcgaaag
     1441 acgagaccgc aaccaatgcc agaaagaata cctgtcatca aactattgat cagtagacta
     1501 tctacagcaa aatgtatatg aaggctctcc cataaatgta aaaagaaaac tagcgcaaat
     1561 gttccgacga tcgtccggag aaaagcgtgt tttccaaaaa gaaacaatga gataagcaat
     1621 aaaggtaaat taaaaagcag tgaagtgaca gaaggagcga atccaaaaag attatgcaaa
     1681 agcaaagcaa taccagtaac cccaccatct gccagcttag atggaatatt gattcctgtc
     1741 acagctaatc cgtagattcc tgcgcctaaa atgattccgc acaattctgt aaataaattt
     1801 aattttttca tttctagcct cttttctttt gaaaattttc agcaacttct ttattatact
     1861 gacttatact cttacttcaa gaggaaaatg aaaaaaaatt atttttggct gtttcttttt
     1921 atttatcaaa taaggagtgg aaaaatgcga gcagcagact tattgacaat tcttacaaaa
     1981 tcacccaaaa aaacagagta tcaaggagtt tttttggctc aagaacaaaa actggtgcct
     2041 gtgacaatgg tccagataaa taaagcaaat caatttatct ttttatttga acacggcaaa
     2101 gcaccacttg ctatgaaaga catctttctt tttttgatga agaaccgtga gaaagctgtt
     2161 tattatcagt caaaagaaga actcattcct ctttatggag tgaaagagat agaaaataaa
     2221 gtggtgatat aagtaaaaat aagaaaacaa gacgtttatg atgtcaaaac aaccattttt
     2281 tacatttttg gcaaaaaagt gtcatgatac agtataatat tcgttgaaca ggccaataaa
     2341 ggtgttctcc cccacgagat ttctacttta ttggctgttt ctttttatta aaataaaagt
     2401 tgtgtgtgta aaaaagatat agctgattcc aagtgacaat ttcgtataga tttttatggt
     2461 attcgtagtg aaaaaacgag aaccaaaaag ttgatccgac tttgttgctt ggattctttt
     2521 tttgtcagca tatttagagg tatttttttc ttttttttgt tcgtgctgta aggttaaggc
     2581 aagacaagtt agttgggaaa aaggaaagaa atgtttatac ttaaagaata acagaaagga
     2641 aggtcgcatg aataatttta tacaaacatt aagtgaaaga aaaggcgagt tgctggaagc
     2701 tgcatttcaa catctgtcca tttctctcat ttctttgctg attgcagcac tgattgctat
     2761 tcctttagcg atttgggcag ccaatcataa aaaaatggca gaagtcttat tgcagatcac
     2821 gggtgtgctc caaacgattc cttcacttgc cttattaggt ttacttatcc catttgtagg
     2881 gatcggaact gttccagcat tgattgcact tgttatttac gctttgcttc cgattttcca
     2941 aaacacgtat attggtctag ctgaaattga cccgtctatt gaagaagcag cggtagcatt
     3001 tggtatgtcc agaatgagac gcttgctgaa agtagagctt cccatcgcat tacctgtcat
     3061 tatctcaggt atccgaactg ccttagtttt aatcatcggt acggctactt tggcagcatt
     3121 gatcggagca ggtggattag ggacatttat tttgttaggt attgaccgaa atacacctgt
     3181 tttgacattg attggtgcga tcagttctgc cttgcttgca attatattca gcggactgat
     3241 tcgctggttg cagcataaga aacctcgata ttccatcatt actttagcag cagtggtgtg
     3301 tttatttggc ggcgtttctt tatatcagtc tgccttgttt aaaaatgaaa ccatcacgat
     3361 tgctggaaaa ttaggagcgg aacctgaaat cctgatccaa atgtataaag aattgattga
     3421 agacaacaca aaaacagaag ttgaattaaa accgaatttt ggcaagacga gttttttgtt
     3481 caatgcactg gatcaaggtc aaatcgatat ctatcctgag ttcacaagta ctgtcctaga
     3541 aagcttggtg aaggtacctg aagcaatgaa aagtgctgat ttgacaaaag aaaaaacata
     3601 tgacgaagca gaagaattat tgaataagca attcgatatg acattattaa aaccaatggc
     3661 ttaccaaaat acgtatgcct tggcagtcaa gagatctttt gcgaacgaac atcaacttaa
     3721 aaagatttcc gatttggcag ctatctctga tcagatcaaa gcgggattca cactggaatt
     3781 tattgatcgt tcagatggat ataaaggaat ccaagaagca tatggcttga atttttcaag
     3841 tgtacaaagc atggagccaa gtttgcgtta ccaagcaatc aataatggag atgtcaatat
     3901 tgtggatgcc tattccacag atagccagct caaggagtac gatctagtga ctctagaaga
     3961 tgatcgaggg ttattcccag cttatcaagg cgcaccgctg atgaaaaaag attttgctaa
     4021 agaacatcct gaaatcgtta aagcactgaa taaattaagc ggaaaaataa cagaggatca
     4081 aatgattgat atgaattacc aagtcaatgt cgaaaagaaa aagccgacag aagtagcacg
     4141 aatcttcctg aaaaatgaag gattagtaaa ggaggaagat cagtgactaa attaatcgag
     4201 ttcaaacatg tgcaaaaaaa gtatgatgga aagtatgtca tcgatgacct aaatctggca
     4261 atcaaaaaag gagaaatctt tgttttggtt ggtccttccg gtagtggaaa aacaactact
     4321 ttgaaaatga tcaatggatt atctaaacca tcagcaggag acatctactt caaaggaaaa
     4381 tcgttaaatg aatataatct gcagaaaatg cggtggaata tgggatatgt gctgcagcaa
     4441 atcgctttgt tcccgaccat gacagtcaag caaaatattg aagtcatccc tgaaatgtta
     4501 ggttgggaaa agcagaaaag agcagaccgt gtagatgaac ttcttcaaaa agttggctta
     4561 tctcctgata tttatcgaga tcgtatgcct agagagttgt ctggaggaga acagcaacgg
     4621 atcgggatca tccgagctat tgctgcaagc ccagatgtga ttttgatgga cgagccattt
     4681 agcgcattag atccgatttc aagaaactca ttacaagaat tggttttgtc cttacacgaa
     4741 gaattgggca cgaccatcgt tttcgttacg cacaatatgg aagaagcaat caagctaggt
     4801 gatcgtattg catttatgaa ggatggagaa attatccaat gtgacacacc agagcagtta
     4861 ttgatgaatc ctaaaaacga ctacgttcgg catttctttg atgaaccgaa acagacgaaa
     4921 gagtggcgag tagaagattt agtcgtcaat ggatatttct taaatgaaat accagaaaat
     4981 gctcgtcaac aagtttgctt tgatacgcct atgaaagaag tatattcgct tctttcggtg
     5041 tatccaagca ttgtgatagt agaaaagcaa agaagtattg ggtcgctgac aagtaaagaa
     5101 atctttgctt ttttaagtcg agaggaggaa ggaaatgaaa acatatgatg caatcatcat
     5161 cggttcaggt gtgagcggct taagtgctgc ttatggattg aaagaagcag gtaaaacagt
     5221 actagtggtc gaagaagatc tatggggcgg gacttgtcct aaccgtggat gtgatcctaa
     5281 aaaagtcttg ttaagtgcag tagaggcacg taatcgggta aaacaattga gtggaaaagg
     5341 ttttaacgag atcccaactg ccaactggga agaacttcaa aaattcaaac gaacatttac
     5401 ggatccagtc ccagaaagcc gaaaaaaaca attagcagaa gctgaaatcg atcatctttc
     5461 aggaaccgct cgttttttgg atgattcatc tattgaagtc aacgaagaag tcttccatgc
     5521 ggattactta gttttggcaa ccgggcaaag acctacgatc ttaccagtgg agggaaagga
     5581 atacttgaaa actagtgcag actttttatc attgcctgta ctgcctaaag aaatcatttt
     5641 tatcggtggt ggttatattg cttttgagct agctacgatt gccaatgctg cagggagcaa
     5701 agtaaccatt gtccatcata atcaacggcc attaaaagaa tttgaggcgt ctttggtaga
     5761 ggaagccgtc catcaaatgg aagcatctgg cattcagttt gcttttggtg ttgaaaccca
     5821 aaagatcatt tcagaaggta ctcgctatcg tttagtcgga aaagagacgg aattagtagc
     5881 agatatgatt ttttgtgcga ctgggagaca gccgaataca gaatctttag cacttgagca
     5941 agcgaatatc gtctttgata aacacggaat tgcagtcaat gattatctgc aaacgagcaa
     6001 tccaaaaatt tttgcgtgtg gagatattgt ttcaaggaaa accccaaaat tgacaccagt
     6061 cgccactttt gaaggaaatt atgtagctaa gcggataacg gatgcaacaa gcgaacctat
     6121 caaatatccg attataccta cgatcgtcta cgccagtcct aaacttgctg aagtaggagt
     6181 tacaaaaagt cacgcctctt cgtcagatca agtggtagag atggatctta ccagttggtt
     6241 cacctatcat cgtgtcaatg aaccagttgc taaggctgaa ttgacctttg accagcaaaa
     6301 ttatttgatt ggtgctgcag tgattagcga gcaagcagac gaattgatcg atgatttgac
     6361 actcgtcatc aatcaaaaat tgactaaaaa agagttggat agctatatca tggggtatcc
     6421 gacattggca agtgatctct cctatttatt gaaataatca gcatgataac taaagcgctt
     6481 gttgcttttt ccttcttgtg ctacacttta aaaaatgaat acctgtttct ggggatgtcg
     6541 tagacgacat gagagtaagt tgtgaactta gacccattga acctgtcagt taatactggt
     6601 gaagggagaa acatagcaga cgcttgaagc gggttactat gtcgtgccca tttcaagcgt
     6661 tttttgttat tcatattaga agaaaggagg taacaaaatg aagaaaaatc tttatccagc
     6721 agtcagtatg gcattcattt taattatttg gcagattgtt gtcatagttt ggaaaatacc
     6781 tgcctttatt ttacccggac ctgctgctgt attttctgca ttagcggcag atgcacaagt
     6841 attactttcc cattctgtca cgacattaaa tgaagcagtg cttggtttgg taatagctag
     6901 cgttctttct tttattactg ccttggcaat ggattattgg aagtttttag aaatgtcttt
     6961 ttatccgtta ctagtgattt cacaaatgtt gccaatcatg gtgttagggc cattacttac
     7021 cctatggttt ggtttcggta tgcttccaaa agtgatcctt gttgtcttga taagctattt
     7081 tccgatcgta gtttcttttt cggatacatt gaggaaagta tcaaaagagc aaatcatctt
     7141 tttgaaaacg atgggggcag atacagggaa gatttatcga atatataaaa taccagcggg
     7201 tttatccggc ttcttttccg gtttaaaagt ggctgctact tattgtgtca gcggagcagt
     7261 cgttggagaa tggctaagcg ctcaagcagg cttagggtat tacatgatac gcgtaaaaaa
     7321 cagctaccag atcgataaag tttttgctgc gatcatttgt gtcattctat tgagtttatt
     7381 gctgaatggc gcttgttcat tattgaaaaa agggtattat cgtatgcttt atatttttta
     7441 agagaagggg atcaaatgaa aaaattatgg cttttattac cgctactgtt gcttttatcc
     7501 gcttgtggca ctgcaaaaga aacaagtagc aaacaagaaa taaaggattt gaaaaaagtg
     7561 acacttgttt tggattatgt accgaatact aatcatactg gcatctacct agcaaaagaa
     7621 aaaggctatt ataaagaggc tggtttaaat gtccaaatca tcgaaccagg agataattcg
     7681 acaagtattg gtctagtagg tgcggacaaa gcacaatttg gtgtaagtta tcaagaagat
     7741 gtcacttatg ctcacgcaga tggacagaat ataccagtca aagcaattgc tacagtgatc
     7801 aaacataata cttctggatt cgccacccta tcagacagta acatccattc accaaaagat
     7861 tttgaaggaa aaacatatgc aggttggcaa agtccaagtg aagaagctgt cttaaaagct
     7921 gtgatggaaa aagacggcgg ggacttttca aaactgacaa tggtaggaag caatggagaa
     7981 gggccagaaa gcttaggaaa atcctcagat atccaatggt actttgaagg ttgggatatg
     8041 atcaaagcaa aagaagcggg tattgaacta aactatatcc cattgaaaga attagatgaa
     8101 cggttagatt actatactcc ggtaattatt acgaatgatc aactgatcaa aagtgatcca
     8161 gaattggtac agtcttttat ggatgccacg aaaaaaggct atcaggaagc tattaaggat
     8221 ccaaatgaca gtgctaaact gttgcaaaaa tatgcaaaag aaaatgatcg gacgttttta
     8281 gaagaatcac aagcattctt gtcaaaaaat tatacggatg atcctgagaa ttggggattg
     8341 atggaagaaa aagtttggcg caattataca gcttttatgc aggaaaacgg attgatcaag
     8401 caagatgtac cttcgcaaga actattcact aatcagttta taaaatagga gtgatagata
     8461 tgtcaatcca aatcagccac ttgaatgtag tcattgaaaa cctgaaaata ttagaagaca
     8521 tccatttcac tatccctaaa gataccttta catcgattgt cgcgccaagc ggagccggta
     8581 agtcaacatt gctgaaaact ttaacaggag tccagcctat gacttctgga acgatcaaag
     8641 tagacgatca aaaagtaact ggtctccata cagcatttag ttatatgccg caagaagata
     8701 tgttacttcc ttggctgagc gtctatcaaa acgttacgtt atatcaaaaa atcaatcatc
     8761 taacaatcaa tgaagaacaa gtaagggatt atctggatat ctttgggtta aacggctatg
     8821 aacatttttt gccggaacaa ttatctggcg ggatgaagca gcgaacggcc ttgttacgaa
     8881 caatcatgaa tccttcttct tacttgcttc ttgatgaacc atttggagcg ttagatgcta
     8941 tgaccagagg gcagatgcaa gactggatgt tgaagctgcc taaaaaagca aagcggacta
     9001 ctttacttgt gacgcatgat atcgaagaag caatttattt atcagacagg attcttgtgc
     9061 tttccgcccg tccggcacat gtgattgctg agattcaagt gcctgaaaaa cgacggtcac
     9121 gtgaatggct actgcagcaa tcagagttga agcaaacgat ttatcagtta ttggcaggtg
     9181 aattagatgt taagtgatgc tcattgtcat ttagatggga gtcagagttt agcactcctt
     9241 cagcaggaac acacgatttt gacgatcatc aattgtgatt cgccagaaga atggaaggaa
     9301 aacagacagc ttgcagcaag taagactcaa gccttaagtt acggtatcca tccttggaaa
     9361 gcagatagct atacgtttga acaagttgag ccttttttga aaaaagcaag gatcatcggt
     9421 gaaatagggt tagataatat ttggacgaat gtaccgatga ctacacaaaa aaaagtattt
     9481 gagcgacagc ttgcttttgc agccataaat gagaaacctg ttgtactgca cacaaaagga
     9541 tgcgaaaaag agatcttaaa ttatatccaa gcttacccta atcactattt gatccattgg
     9601 tattcttctt tggactatca acaagactat attgatttag gctgttattt cagcattggt
     9661 cttgatttga aaaagaatcc agcagtctgg caactagcta aagcagtccc aatcgaccac
     9721 ttacttattg aaacggatgg actacatgca gcagagtggg ctttaggggg gattttttca
     9781 gaaaaagatt atgtctcact gcttgaagaa cagttaaaga caatcgctga gatcaaagag
     9841 ctatcagttg aagaagttaa aaaaaatact tatcaaaact tggaacgttt cattagatta
     9901 ggtaaataaa aaagagatgt gacacaacta gtgtcgcacc tctttttggc tttctttgta
     9961 taaaagtaaa ctgtttgatt aataaatgaa tcttagtacc aaccgtttgc ttcccagaat
    10021 gctttcgccg cttcccaaga accataacgt gaagtaacat attgttctgc tactctttct
    10081 tggtttgcag cagagtagtc accatttaag taagaagaat ctaattggta acgtccgatg
    10141 taacgtccgt tcgttgctgt gtaagaaccg cttgattctt tttgtgcgat ccattctttt
    10201 gcagagcttg tgcttgctgg agtagcagca gtttctgtta cagcaggagc aggttgtgtt
    10261 tcagcaacag gcgctgcttg tttttccgtt tgaaccgttt cttgtacaac aggttgttca
    10321 gcttggactg gtgcttcttg aacggctgct tgaggttcag cagctgcttg tgcagagcct
    10381 tctgttggga ttgttaattg ttgtcctgag ta
//
LOCUS       DAXLPY010000081        10022 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.081, whole genome shotgun sequence.
ACCESSION   DAXLPY010000081 DAXLPY010000000
VERSION     DAXLPY010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.081"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..722)
                     /locus_tag="ACF3UF_002319"
     CDS             complement(<1..722)
                     /locus_tag="ACF3UF_002319"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3672395.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     KPGMATVFLTNFIRCRTSFRML"
     gene            complement(727..1494)
                     /locus_tag="ACF3UF_002320"
     CDS             complement(727..1494)
                     /locus_tag="ACF3UF_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3672396.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1983..2408
                     /gene="lacA"
                     /locus_tag="ACF3UF_002321"
     CDS             1983..2408
                     /gene="lacA"
                     /locus_tag="ACF3UF_002321"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFD3672397.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2425..2940
                     /gene="lacB"
                     /locus_tag="ACF3UF_002322"
     CDS             2425..2940
                     /gene="lacB"
                     /locus_tag="ACF3UF_002322"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFD3672398.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2951..3883
                     /gene="lacC"
                     /locus_tag="ACF3UF_002323"
     CDS             2951..3883
                     /gene="lacC"
                     /locus_tag="ACF3UF_002323"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFD3672399.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3886..4866
                     /gene="lacD"
                     /locus_tag="ACF3UF_002324"
     CDS             3886..4866
                     /gene="lacD"
                     /locus_tag="ACF3UF_002324"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFD3672400.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4894..5211
                     /locus_tag="ACF3UF_002325"
     CDS             4894..5211
                     /locus_tag="ACF3UF_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3672401.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5211..6917
                     /locus_tag="ACF3UF_002326"
     CDS             5211..6917
                     /locus_tag="ACF3UF_002326"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HFD3672402.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7059..8465
                     /gene="lacG"
                     /locus_tag="ACF3UF_002327"
     CDS             7059..8465
                     /gene="lacG"
                     /locus_tag="ACF3UF_002327"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFD3672403.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRLKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8488..8761
                     /locus_tag="ACF3UF_002328"
                     /pseudo
     CDS             8488..8761
                     /locus_tag="ACF3UF_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
     gene            8782..9681
                     /locus_tag="ACF3UF_002329"
     CDS             8782..9681
                     /locus_tag="ACF3UF_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFD3672404.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDEDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSSLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3164 a         1690 c         2006 g         3162 t
ORIGIN      
        1 aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac tgttgccatt
       61 ccaggtttat gacgactttt ggaagtaaaa atccatccat tatctttata atcaggattg
      121 aatcttatat gttggtgatt taactcaatt tcctctttaa gaatttctat agccctttta
      181 gataattgga cattttggta actttgtaag ttttttacat taccttcata gctattttct
      241 gcagctcctc cgtgagtgga ctgactaatg atgatatttt gcttttcaaa atattgatag
      301 gcaccaatat tttggagttt tcgactctgt aagtcaacag ggccattagt tagaatacct
      361 attgggatgc ggtttttatg tagagccagc agtagttgat gtatctcagg aatcatcgta
      421 atctgatcga gttcatattc atagtcagct tggaagtcta gagcttctgt cctagaaata
      481 ctatcgatgc caaattcttc catagtcttc tgacagcgaa aaattctaag ctgctcaata
      541 ctgatgagtt ttttcgtgta tttaggaaaa gcaacatcag accaacatct gaaacgtttg
      601 taaatgttat ctatttgttg gatatcaatc gttggaaaac atttctcaac gctacgttta
      661 aaggggagtt gatggtcata aagagtgtca tcaaggtcaa aaacaatatt tttataagtc
      721 ataattctag tccgctttta aaatagtagt gtactggcta aattcctcta agtgttgagg
      781 gctaatctgg ttatctgtaa tgatggtatc gagttgatct agattataga agttaaagaa
      841 atcgtatcga tcgaatttag tactgtctac taataagaat ttttctacag cattgtttag
      901 ggcaagttgt tgaatcacac cttccttgtc actatatgta gcaatagaat tatgggtaac
      961 agcatttgca ctaacaaaag ctttggcaaa tctaattgct tttaaatttg tcgaagccat
     1021 tgaacctaca aaagctccag ttatttctct atattcaccg ccaagaagca ataaatcaat
     1081 ggtttcgcta tcatttagaa tcaagaacac agggagacta tttgtaatga cacgaatttt
     1141 ataaccttta cgacctttca attctaatgc cagttgttca agtgtagttc cgggtccaat
     1201 aaaaatagta tcgccatctt tgattaaaga gcaggctttt ttagcaatgt caattttttc
     1261 ttttgtattt agacttttct tctcgatatg tgtcttttca agtggctttt tagaggaaag
     1321 taattgtgca ccaccatgag tacgtgttaa aagtccatca gcttctagag catcaaggtc
     1381 tctacgggct gtcatatcgg aaatatctag ttcatctatt atttctttta tggttatggt
     1441 cccatcaatc tttaacatat ctaaaatttt ttctaatcgt cgttttttgt tcatatgaag
     1501 acccttcttt cataaagtaa tttttttcca aagataattc tcttttaatt gtatcataaa
     1561 agacaatatt ttcaaggtaa aacaaacaat ttcaaacaaa aacaaatgtt agatgatgaa
     1621 ataagaacag tggattgacg tatattagct taggtcagat tttgtataag acgaaaataa
     1681 agtaggacct cttaatcagt aagttataga aagtaaaaga cttttgtaat acttgaatag
     1741 atatttcacg tccattttgt gatggattaa atgaacaaaa atgaacaata atttaacggt
     1801 gttatctatt ttttaagaaa acaaataaaa aaaacaaaaa ataaacaaaa aagtgttgct
     1861 ttttgtttga atgattgata ttatataaac aaagaaatga tgaaaacgtt ttttcgaaca
     1921 ttttgcaaaa tgttttctac ttctacgtag catttctttc taaaatttag gaggtggtca
     1981 aaatggctat tgttgttggt gcagatctca aaggtacgag attaaaagat gttgtgaaaa
     2041 attttcttgt agaagaaggt tttgaggtaa ttgatgtgac taaggacgga caagattttg
     2101 ttgatgttac cttggcagtt gcctctgaag taaataaaga tgagcaaaac ttaggtattg
     2161 taattgatgc ttatggagct ggtccattca tggtagcaac taaaattaaa ggtatggttg
     2221 cagcagaagt ttcagatgaa cgctcagctt atatgacacg tggacataac aattcacgaa
     2281 tgattacggt tggcgctgaa atcgtcggtg atgagcttgc taaaaacatc gctaaaggtt
     2341 tcgtcaatgg taaatatgat ggcggacgtc atcaaatccg agtagatatg cttaacaaaa
     2401 tgtgttaaga aaaggagtta aggaatgaga atcgcaattg gatgtgacca cattgtcaca
     2461 gatgaaaaaa tggcagtatc agaattcttg aaatcaaaag gacatgaggt ccttgatttc
     2521 gggacatatg accacgcacg tactcactac cctatctatg gtaaaaaagt cggtgaagca
     2581 gtagtaagtg gtcaagcaga cttgggagta tgtatctgtg gtacaggtgt cggcattaac
     2641 aatgcagtca ataaagttcc aggtgttcgc tcagcgttgg ttcgtgatat gacatcagct
     2701 atatatgcaa aagaagagtt aaatgcgaat gttatcggtt tcggtggaaa gattactggt
     2761 ggtcttctta tgaatgacat cattgaagct ttcattgaag ctgagtacaa accaacagaa
     2821 gaaaataaaa aattgattgc aaaaatcgaa cacgttgaaa cacataatgc acatcaagca
     2881 gatgaagatt tctttacaga attccttgaa agatgggacc gtggtgacta ccacgattaa
     2941 ggtataacaa atgattctga cagtcacact aaatccttca gtagacatct cttatcctct
     3001 agaaacattg aaaattgata cagtgaatag ggtgaaagat gttagtaaga cagctggtgg
     3061 aaaaggctta aatgttacta gagtcttgta tgaatctggt gataaagtta ctgctacagg
     3121 tttcttaggt ggtaaaattg gtgaatttat tgaaagcgaa ttagaacaat ctcctgttag
     3181 tccagctttt tataaaatct caggaaacac tagaaactgt attgctatct tacacgaggg
     3241 taaccaaaca gaaattttgg aacaaggacc aacaatttct catgaagaag cagaaggctt
     3301 tcttgaccac tatagcaatc ttattaaaca atcagaagtt gtgacaattt caggaagttt
     3361 accttcagga cttcccaacg attattatga aaaacttatc caacttgctt cggatgaagg
     3421 agtagcagtc gttttggatt gttcaggtgc acctcttgaa acagttctaa aatcgtcggc
     3481 taaacctact gccatcaaac ctaataatga ggaactttca cagttgcttg gaaaagaagt
     3541 aacaaaagat attgaagaac tcaaagacgt tcttaaagag tcacttttta gtggtatcga
     3601 atggatagtg gtctcattag gtcgaaacgg tgcctttgca aaacatggtg atgttttcta
     3661 taaggtagat attcctgata tcccagttgt taatccagtc ggatcagggg actcaacggt
     3721 agctggtatt gcatcagctt taaatagtaa aaaaagtgac gctgacttat taaaacatgc
     3781 gatgacattg ggtatgttaa atgctcaaga aacaatgaca gggcatgtga atatgactaa
     3841 ttacgaaaca ctaaactcac aaattggagt aaaagaggta taaaaatggt acttacagaa
     3901 cagaaacgca aatctttgga aaaaatttca gataaaaacg gtgttatctc agctttggca
     3961 tttgaccaac gtggtgcttt gaaacgtttg atggcacagt atcaagatac agaaccaact
     4021 gtagctcaaa tggaagaact aaaggttttg gttgctgatg aacttacaaa atacgcttct
     4081 tcaatgttgc ttgaccctga atatggactt ccagcaacaa aagcattgga taaagaagca
     4141 ggtcttcttc ttgcctatga aaaaacaggt tatgatacat caagtacaaa acgtttgcct
     4201 gactgcttgg atgtttggtc tgcaaaacgt atcaaagagc aaggcgctga tgccgttaag
     4261 ttcttgcttt actatgatgt agacagctca gatgaactta accaacaaaa acaagcttat
     4321 attgaacgtg ttggttctga atgtgtcgct gaagatattc ctttcttctt ggaaatcctt
     4381 gcttatgatg aagaaatctc agatgcaggt tctgttgaat atgcaaaagt gaaacctcgc
     4441 aaagtcattg aagcgatgaa agttttctct gatccacgct ttaacattga tgttcttaaa
     4501 gtagaagtac cagttaacgt taaatatgtc gaaggttttg ctgatggtga agtggtttac
     4561 agtaaagctg aagctgctga cttctttaaa gcacaagaag aagcgactaa ccttccatac
     4621 atctacctaa gtgcaggtgt atctgctaaa ttgttccaag aaacattgca atttgctcac
     4681 gactcaggtg ccaagtttaa tggtgtgctt tgtggacgtg ctacttgggc aggatctgta
     4741 gaaccttaca tcaaagaagg tgaaaaagca gcacgtgaat ggttgcgtac tactggattc
     4801 gaaaatattg atgaacttaa caaagttctt gttaaaacag ctagtccatg gactgataaa
     4861 gtatagtaaa aacataaaac ggaggatatt gttatgaaca gagaagagat gactctctta
     4921 gggtttgaaa ttgttgctta tgctggagat gctcgctcta aacttttaga agcgcttaaa
     4981 gcggctgaaa atggtgattt cgctaaggca gatagtcttg tagtagaagc aggaagctgt
     5041 attgcagagg ctcacaattc tcagacagct atgttggctc gagaagcttc tggggaggaa
     5101 cttccataca gcgttaccat gatgcatggt caggaccact taatgactac tgtcttatta
     5161 aaagatgtga ttcatcacct catcgaactt tataaaagag gagcaaaata atgcataaac
     5221 tcattgaact tattgagaaa gggaaaccgt tctttgagaa aatctctcga aacatctatc
     5281 ttcgtgctat tcgtgatgga tttatcgctg gtatgccagt catccttttc tcatctatct
     5341 ttatccttat tgcctatgtc ccaaatgctt ggggattcca ctggtcaaaa gacattgaga
     5401 ccttcttgat gactccttat agctattcga tgggtatcct agcattcttt gttggtggta
     5461 ctaccgctaa agctttgacg gactcaatga accgtgacct acctgcgacc aatcagatta
     5521 acttcttatc tacgatgcta gcgtctatgg tagggttcct tttgatggca gctgagcctg
     5581 caaaagaagg aggcttcttg acagccttca cgggaacaaa aggtcttttg acagcattta
     5641 ttgcagcctt tgtgacagtt aatgtttaca aggtctgtgt gaaaaataat gttactattc
     5701 gtatgcctga agaggttcca ccaaatatct ctcaagtatt taaagacttg attccattca
     5761 ctgtagcggt tgttctcctt tatggatttg aactcattgt taagggaact cttggtgtaa
     5821 ccgttgcaga atcaatcggt acccttcttg ctcctctctt ctcagctgca gatggttacc
     5881 ttggaattac acttatcttt ggtgcttatg ccttcttctg gtttgttggt atccacggtc
     5941 cttcaattgt cgaaccagca atcgctgcta tcacttatgc caatatcgat gccaacttgc
     6001 atcttatcca agctggacaa catgcagata aagttatcac ttctggtact caaatgttta
     6061 ttgttaccat gggtggaaca ggagctacat tgattgttcc attcttgttc atgtggattt
     6121 gtaaatcaga acgtaaccgt gccatcggac gtgcctcagt tgttccaaca ttctttgggg
     6181 ttaatgagcc aatcttattt ggtgcaccaa tcgtattgaa tccgattttc tttgtaccgt
     6241 tcattttcgc tccgattgtc aacgtttgga tctttaaatt ctttgttgac acattgaaca
     6301 tgaactcatt ctctgccaac cttccatggg ttactcctgg tccgttggga attgtactcg
     6361 gtactaactt ccaagttcta tcatttatct tagccggact cttggtagtt gttgatacta
     6421 tcatttatta cccatttgtt aaggtatacg atgaacaaat tcttgaagaa gaacgttctg
     6481 gtaaaacaaa cgatgctctt aaagaaaaag tagctgcaaa cttcaatact gctaaagcag
     6541 atgccgttct tggaaaagca ggcgttgcta aagaagatgt agcagcaaac aataatatca
     6601 caaaagaaac taatgtcctt gttctttgtg caggtggagg tacaagtggc ttgcttgcca
     6661 atgccttgaa caaagcagca gcagaataca atgttccagt caaagcggca gcgggtagtt
     6721 acggtgctca ccgtgaaatg ttgccagagt ttgacttggt tatcttggct ccgcaggtcg
     6781 cttcaaactt cgatgatatg aaggctgaaa cggataaatt gggcattaaa cttgcaaaaa
     6841 ctgaaggagc tcaatatatc aaattgacac gtgatggaca aggtgctctt gcatttgttc
     6901 aacaacagtt tgattaataa atttgtaaaa gttatttgag acgagattat tctttcagtt
     6961 ccttataata ttgttaacca tatcattgca tttcatttcc ttggtttccg gaactcagaa
     7021 tatcgtctca aatgcttttt ttgaaaggat ttatagttat gactaaaaca cttcctaaag
     7081 attttatttt tggtggtgct acagctgctt atcaagcaga aggtgcgact cacacggatg
     7141 gtaaaggccc agttgcatgg gataagtatc ttgaagacaa ttattggtac acagcagagc
     7201 ctgcaagtga tttttaccat aaatatcctg ttgatttaga attagctgaa aaatatggcg
     7261 ttaatggtat tcgtatttca attgcctggt ctcgtatttt cccaactggc tatggcgaag
     7321 taaatgaaaa aggtgttgaa ttctaccata atctttttgc cgagtgccac aaacgtcatg
     7381 ttgagccatt cgtgactttg caccactttg acacaccaga agttcttcac tcagatggag
     7441 atttcttaaa ccgcgaaaat atagaacact ttgtagatta tgccgctttc tgttttgaag
     7501 agttcccaga agtaaactac tggacaactt tcaatgaaat tggcccaatt ggagatggtc
     7561 aatacttggt tggtaaattc cctccaggca ttcaatatga tcttgccaaa gtcttccaat
     7621 cacaccacaa tatgatggtt tctcatgcac gtgctgtgaa attgtataaa gataaaggtt
     7681 ataaaggcga aattggtgta gtacatgcgt tgccaaccaa atacccttat gatccagaaa
     7741 atccagcaga tgttcgtgcc gctgagttag aagatatcat ccataacaaa tttatcttgg
     7801 atgcaaccta ccttggacac tattcagata aaacgatgga aggggtcaac cacatcctag
     7861 ctgaaaatgg tggagaactt gatcttcgtg atgaagactt ccaagcactt gaagcagcta
     7921 aagatttgaa cgatttcctt ggtatcaact actacatgag tgattggatg caagcctttg
     7981 atggtgagac tgaaatcatt cacaatggta agggtgaaaa aggaagttct aagtaccaga
     8041 ttaaaggtgt tggtcgccga atcgcaccag attatgtgcc tagaacggat tgggactgga
     8101 ttatttatcc tgaaggcttg tatgaccaaa tcatgcgatt gaaaaatgat tatccaaact
     8161 acaagaagat ttacatcact gaaaacggtc ttggatacaa agatgagttt gtagataata
     8221 ccgtttatga tgatggtcgt attgattacg tgaagaaaca cttggaagtt ttatcagacg
     8281 caattgcgga tggtgcaaat gttaaaggtt acttcatctg gtcacttatg gatgtcttct
     8341 catggtcaaa cggatacgaa aaacgttatg gactattcta tgtagacttt gacacgcaag
     8401 aacgctatcc taagaaatca gctcattggt ataagaaagt agcagaaact caagtgatag
     8461 agtaatatta cttgaaaatg taaaaaattg ttatccgata ctttagaaaa agtacaacac
     8521 ttatttagac caggctttga aaaggtatat attgttagtt tcgaagattg tcctatgatt
     8581 cctgagcttg aagctaccct cgttgctaaa atgtggtaaa tggtatgttt taactggaaa
     8641 agagtggatt tgccattctg atttagagtt atcagcattt gaatgggaat ttttacaatc
     8701 actcgatgta gaaatacgtg agactattca cttcgaggta aattatttgc ctttccaata
     8761 ataaaaagaa aggaattagt tgtgactatc gaattaaaaa acgagtatct tactgttcag
     8821 tttaaaacac ttggtggtca actgacttcg attaaagacg aggatgggat agagtatctc
     8881 tggcaagctg atccaaatta ttggaatgga caggcgccta ttctatttcc tatctgtggt
     8941 agtttacgaa atgattgggc tatttataga cctcaagaaa gacctttttt tacaggtctt
     9001 attcgtagac atggttttgt tcgaaaagaa gaatttattc tggaagaagt caatgataat
     9061 agcgtgacct ttagtattaa accaaatgct gagatgcttg ataattacct atatcagttt
     9121 gaactgagag ttgtttatac cttgaatggt aaatcaatta gaaccgaatt tcaggtaacg
     9181 aacttggaaa tggaaaaaac aatgccttac tttattggag cccatccagc attcaatagt
     9241 tctttagtag aaggtgaaaa ctatgaggat tattatattg aatttagtga ggttgagtct
     9301 tgctcgatac caaagagttt tcctgagaca ggattattag atttgcaaga tcggacacct
     9361 tttttggaaa atcaaaaaat tctcgatttg gactactcac ttttttccca tgatgccatt
     9421 acacttgacc agctcaagtc tcgtagcgta acgcttcggt caaggaagtc tggtaaaggt
     9481 cttcgagtag attttgatga ttttccgaac ttgattctgt ggtctacaac taataaaagt
     9541 ccattcattg ctttggaacc ttggagtggt ctctccactt cacttgaaga aggtaatttc
     9601 ttagaagata aaagacaggt aacgaaaatt tcacctcaag aaacttctag aaaaatctat
     9661 gatattacta tccttaatta aaatttgtta ttatttgagt cttcaataag atttgaatac
     9721 tcttaccttg tgatgataga ttggtcttct ccgtgccagt cttacatcgc aaggttttta
     9781 agttttttgt gggtctatgt caactgtagt gggtgacgaa aagctaatat ctaaagacag
     9841 tctggtagta aaaaataaga ttatttacta cttcttgatt taaaataata gtggagccat
     9901 taatttgtgg caaatttaat ttaatatttt gcctcaaatt agccacactt tttatagaac
     9961 taagaggaaa aatgaaattt tcttcctatt aatatagttg tttgaaatct taaatatagc
    10021 gt
//
LOCUS       DAXLPY010000082         9753 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.082, whole genome shotgun sequence.
ACCESSION   DAXLPY010000082 DAXLPY010000000
VERSION     DAXLPY010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.082"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            212..418
                     /locus_tag="ACF3UF_002330"
     CDS             212..418
                     /locus_tag="ACF3UF_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFD3672405.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(620..1621)
                     /locus_tag="ACF3UF_002331"
     CDS             complement(620..1621)
                     /locus_tag="ACF3UF_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3672406.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1626..3538)
                     /locus_tag="ACF3UF_002332"
                     /pseudo
     CDS             complement(1626..3538)
                     /locus_tag="ACF3UF_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            complement(3706..4212)
                     /locus_tag="ACF3UF_002333"
     CDS             complement(3706..4212)
                     /locus_tag="ACF3UF_002333"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFD3672407.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4372..4812
                     /locus_tag="ACF3UF_002334"
     CDS             4372..4812
                     /locus_tag="ACF3UF_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3672408.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(4838..5866)
                     /locus_tag="ACF3UF_002335"
     CDS             complement(4838..5866)
                     /locus_tag="ACF3UF_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672409.1"
                     /translation="MYWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWIS
                     LLRISLQRMKQGHSITYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTE
                     QAYLYFMFGVMNTYLEEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLY
                     VNLAMIHLYSRVFGTKKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNT
                     YYEKNRRLIFQYCMLVRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYS
                     ASADQLPDIVISDYPIDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSI
                     LEKLDFVN"
     gene            complement(5921..5995)
                     /locus_tag="ACF3UF_002336"
                     /pseudo
     CDS             complement(5921..5995)
                     /locus_tag="ACF3UF_002336"
                     /inference="COORDINATES: protein motif:HMM:NF016901.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5998..6354)
                     /locus_tag="ACF3UF_002337"
     CDS             complement(5998..6354)
                     /locus_tag="ACF3UF_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672410.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(6652..7626)
                     /gene="sgrA"
                     /locus_tag="ACF3UF_002338"
     CDS             complement(6652..7626)
                     /gene="sgrA"
                     /locus_tag="ACF3UF_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFD3672411.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(7822..8661)
                     /locus_tag="ACF3UF_002339"
     CDS             complement(7822..8661)
                     /locus_tag="ACF3UF_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFD3672412.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            8846..9733
                     /locus_tag="ACF3UF_002340"
     CDS             8846..9733
                     /locus_tag="ACF3UF_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFD3672413.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
BASE COUNT         2937 a         1962 c         1463 g         3391 t
ORIGIN      
        1 tctattatat tcccatattt tctattattg gtctagacgt atgatggtaa actttgtacc
       61 tatctgattg ctgaatcatt aattgcttat cattagccat ctttgtttca agttcgctag
      121 atgatcattt tattcacatc ctaacaaact tgtcacattt atagattctt aatctattta
      181 tcatacaatt ataaaaaagg aggtgctgct tatgaaagct atccatattt ctttgctttt
      241 tttcgctagt gcattgattt tatttgctat tcatctttgt tcccagcctt atatcaataa
      301 caacggaata ttagtggaac cagcattctt ttgcttacca ctcggctttt tgtcccttct
      361 tgcctccgca ggcttcggat ttgttgcttt ttttaaacga tcaaaacaac aaatctgact
      421 tataaaattt acgtaaaaga gatcgtgaca ataatcgtgt gatattccca aatttcgaat
      481 aaaaggtgcc ccttgccatc tctaactcct cagtcacaag ttacaatatt cataaaccat
      541 gaaaagcttg tttattgaaa ttgctccttg tgacttggag ctaagtgaca gattacaacc
      601 tcttttgcat cataagactt tactccttga aaaacattac taacttttga tatgtttctt
      661 gcgcttgttt attgctgaaa tcaaactgat attcatggtt caaaacagca tttttctccg
      721 cataatctac ttttgtgact ttcacccccg ctttctcaaa tacagaagtt acttcttcca
      781 tttgtttcgt aaacgtattt gtatttccat ccgttaagaa tgtgttttgc gtccaacgat
      841 ccgcatgtct gaccaaggct aaacttttga ccttctctga ttgttcaaag tccttattat
      901 caaagtaagc ccatccacat ttttcataaa gaaagctaga gattttatca cttacttgag
      961 taagtgcaga aggatccaac agaccagaca aagaaataaa cttcgtaatc tgcttgttct
     1021 ccaaagtcgg atcaagatga tcagcttttt taatttcttc attttgaagt gctaacaaat
     1081 attctccact aatttgtgca cctgccgaat ttccaccaat cgaaatattc gaccaatctg
     1141 cttgatcttt tatctctttt ttagctgctt gaatggcttc gttcaattgg ataactggtg
     1201 taggatgttt tgcttccggt gatcgttcat aatctatatt tacgatgatt tgctgcgtgt
     1261 ctgaacatag atattccaaa taatcacgac aatcattttt atcccctcct acatatgcgc
     1321 ctccatgcat ccagaaaaga atcggtaatt ttttcttttc cactttcggt gtgtagatat
     1381 ccatattatt atttttgtac tttgaaggat aggatatttc tttttttata tcgatttgtt
     1441 cgattttttg ctggaaatca tctggtcggg catatacttg ttctttttca cttgtgtcaa
     1501 attgttttct aacaagcaag ctaatcggct ttggtgtgat ttgattaatc aaaaatacag
     1561 tgactaaaat aactacgatg ataactggta ctgcaatcac tattcgcttg aaccatttca
     1621 ttcatttacc ctctctttct tcgccaaatc catgtgataa tcgtgctaac agataaaaat
     1681 ccacctgaat aaatgagaag cgaatgtttc ttttctccag ttttcggcaa cattcttttt
     1741 ttgcatctgt ctttttttgt actttcactg tcatctgaat cggttgcgta tcatcacttg
     1801 attgatcctc tcgaggttca ttctttccct tattgtctgc attctctgtc ggatcttgct
     1861 tttttggtgg agctactggg atttttttgt aatagaaaat aatagttggt atcgtctcat
     1921 taaaaatccc ttcagtcggt ccttcaacat ttgctaattc gtatccttcg aatgtctttt
     1981 gctctgtcat ataattttct ccataagctc cgtaaagctg gatttcgtcc tggtctttga
     2041 gtagactttt attgttttca tccacatact ttacgtttat ctgatcatgg aacactactt
     2101 tcaaaaagtc cgttacatgt ttcgtgtagg cagcatggtc aacttcctgt gcctttccat
     2161 gccctgctcc ttctactaat aaaagatctt tataccctcc tgataactca tataattttt
     2221 gcgcgttaga cacaggtact acatcatctg ctgttccatg gataatcaat ttaggcaatg
     2281 aatctgacat tccaatcgta ggtagagcag cttttgtatc caaatgcatc tcctgatcaa
     2341 aatagtattg tttcaaaagg cccataaata aatcttcatg ctcttgatcc ccaatgatgt
     2401 ctaactgatt ttttatggca tccggtagtg cgggggctac tgtctggctg tacgtaaaac
     2461 gtagttgttc atcaattgat gcaaatccgc aattttcaat aattcctttg acattgacag
     2521 gaatatcttt cgctaataca gacatcatcg tagctgctcc catcgaacca ccataaagta
     2581 aaatcttttg agatggccgc tctcgaactt cttgatttat ccagtaaagg acgtcatctg
     2641 actcatattg tccataggtc acataatcgc ctccgctatt accagtcgct ctggaatcaa
     2701 caaataataa attatacccg gccttataaa aatcattgta ttcttctgta acgatcccgt
     2761 tattccaatt ccctcgaaat ccgccatgga tcatgactgt tttatctgaa ccttgatcga
     2821 cataatatgc atatacatcc atcattttgc catcttgttt gtttagtaca gtttgatgaa
     2881 gttgttttgt atttggatag aagcctgtgt tttctgtagg cgttgtccca tcatctgtac
     2941 ctccaagcat cgacatcaac acactgtttt ttgcaaaagc gatatcgtac aatagataag
     3001 tagcaatcag atgtttgata atctctttat ctacaccata atcattaaca gcaagctcag
     3061 tgactaataa ctctattaat tttgacttga tgtcttctgt tggtccatta agtatttctg
     3121 tcatctgttt accgaagtaa ttcaaatatt ctttaccatt gaaattttca cctttaccga
     3181 tatcatcatt ttctgtccca ttctctttgt cacttacttt agcagaagag gattcgtcgt
     3241 ttgacatttt tgtagctgtt gcttcttctg tttgttggtt atctgtggta gcggtcgttt
     3301 cttgatctgt gctagtaaca gatgtctcaa ccgttgtttc agtatttgtt tctgtttgtg
     3361 aagtactcga tttcgtttca tttccagcat cagtagtttc tgtggtttct acctcccgag
     3421 attccgattc ggaagaaatg ctctctccat atactgtcca ttgcgggacg cttgtactta
     3481 cagcaaataa gatgaccaac gctcccttta atacttgttt tgttctcaag ctattcactc
     3541 ctttttatgt ttctaggaga attatatgta aacgcaaaca ttttttatac aaaaaataaa
     3601 tggtttatcc cataaaaata gaacaggatt attttctcat tttacgtaat aaagcagaat
     3661 ggataaacca gtatccattc tgcttttttt aaacgaagaa acaacttatt gctccaaaaa
     3721 tgtcagaaat cgtttatccc aaattttctc gtaaaaagcg attgtttcct ttgctttcat
     3781 aaaaggatta tcataagttg tcgttgctcc tctacacatc ataagctggt atcctaatcc
     3841 atgagcaaac ttcacagtcg tatctataca atactctgct tgtgccccac ataattcgat
     3901 cgaatgacag tccaattcag ttaataaaac actcaaatta gtcttataaa atgaattcgc
     3961 atgggttttt ctcacaaaat aactgtgctc aggaatagat aattccgaca atagctccca
     4021 tggttttgtt tgtggcacta attgagcatc ttcgtgttga acgaaaataa ctggtttccc
     4081 aatcgtttcg tatgttttga ttcttttatt cactaatgct gtcactgttt ctaattcgtg
     4141 tatcggcgaa gaatcaaaac ataccccttt ttgtaaatcg atcactacta ttgcgtcggc
     4201 tgtgtttgac atacttgtgc cttctttctt ttttcttgat ttaatagtat ttcttatcta
     4261 gctagttcca ttatacgtga caacattttc ttattttaca cctctaaatg gcacttttcg
     4321 actatttctt catgttatta tttcataaat acttagctat tggaggaatg tatgatgatt
     4381 aaattgtata caggttctgg ctgctcgtct tcaagacgcg caaaacgttg gcttatcgtc
     4441 catgatatac cgtttatcga acagaactta attcgtcaac cactaaccaa aaatgaattt
     4501 atccacttac taaaattgac aaacaacggc gtgaccgaaa tgctctctac tcattctatt
     4561 agttataaaa atcttgttca cagaatagat gaactcagtt tgagtgaact atatattgag
     4621 attcgtacat ccccttcttt attgaaaaaa ccgattatct acgaccaatc tgcaaaactt
     4681 ttgactggat ttagcgaaga taaaatcagg atgttccttt ctaaaactaa aagaaagcaa
     4741 gagctcaacg aactcttgct ttctggtcat cttgtcgatt ttaaagaaaa taatcttttt
     4801 gcaatgtctt aattttggca taaacaatct gcttttctta attaacgaaa tccaattttt
     4861 ccaatatgga tctatttttc tcattcctga tttttatgat ttcagctttc agacgcgccc
     4921 aatcattttt tgtaggttgt ccattccagt aaaatatctg tgtattcgtt tgatcatatg
     4981 cctttttgtc gataggataa tcgctaatga caatatcagg taactgatca gcggatgcac
     5041 tatattttat tgggcgttca gtcatagata atatcctttt ctttgcccat aattcctgtg
     5101 ttttaccata ctttgattga atatagaata tgacaggttg ttcgtgtttt ataaaaatat
     5161 ccctgactaa catacagtat tgaaaaatca accgtctgtt cttttcataa taagtattaa
     5221 gctctggaat tctgcgagct accccactaa aaaactgttg catgattgga tacatcactg
     5281 gaaatatatg ctgaaaatct ctgtcttctg ctgattttcc aaaagcatcc accttctttt
     5341 ttgtcccaaa aacccttgaa tacaaatgga tcattgccaa attgacatat agataatttt
     5401 tttctgaagt tgtaaaacaa atcttgaagt ttttttcaaa attttctaca atagacgatt
     5461 caatccagcc ccaactttct tgtactttat ctggagtatc caacaaatct tcttccaaat
     5521 aggtgttcat tacaccaaac ataaaataaa ggtaagcttg ctctgttgga gtgatgtgat
     5581 tcatcgacca gaagtttgct tcaaaaaaag gctctagtat gtaatgcgta aactcttctt
     5641 ttgttatcaa tggatgcaca aatttgttca tctcttctgg gacatacgta atcgagtggc
     5701 cttgtttcat tcgttgcaac gaaattctta gtaggctgat ccatttcttt ctatctatac
     5761 tacgcgtata tggcgcatgt ttcgcaaatt tttctaatag ttgacgttta ttttttatac
     5821 ttgataatat atcagaatga ttttcgtcga atgactgcca atacatcaag tgaaaaaagt
     5881 atcggatacg gtattcttct ccttctatcg gattaccttt tttcaagctg caagataaat
     5941 gatagttttt caaaatagta ttaagttctc ttaattttct ttgaatcgta cgcaaactta
     6001 tataattttt tgactaagat tttctaagga ttgataagta cctttgtaaa gtgaatccag
     6061 taaaatataa ccaatcgttc cctctaaaag tatagaataa actttactca gtaaaaactg
     6121 agaagaaaac tcgactttta tcatcttgtt ttctgaaaga aaagataatt tatattctgg
     6181 atacctttcg caaaacgatt ctgcttgttg aatcaccgaa ttcatcttag ccagggtgta
     6241 gtttagatct aaagcgatat ccttcaccac atataatttc tcgtctcttt cataacaata
     6301 gttcaaaaat tgatatactt gcctttcatt gatatcaata aattcttcaa acaaagtaca
     6361 tactcctttt tatctattat ttagacttat tccgacagct acatgaataa cgtacaaata
     6421 gattcgttac tgatttttca gagatactac catgcgcagt gtgcattgtc aattattctt
     6481 gctcttattt tccatttgtg ttcctgttat ttcctgtttc tcaaatatgt tagtaaacaa
     6541 aaatagatct ggcaaagcta caacttcgcc aggcaataca gcactctcga atgaaatatt
     6601 cactcaaaaa tctatcgttt tattcaattt tagatctgtt gcttttattc tttatttcac
     6661 tcgatggaag agagaacgaa aatagcttgc tcctacaatc aaaatgagta acacacccat
     6721 ccatgtaatt agcttgttca aggttctact accagtttct ggtaaatcgc tttttctatt
     6781 atctgtttct ttcgcttttt cttgatgatc aattccacga gaaacaaaat caggctgttt
     6841 tagcacactt tttaggttgc tccctgcatt tctcttttgt tccttagttg gtatgatagg
     6901 taccaaatca agttcattat ttacttttcc tgtgctgctt tcgctgctcg tgcttcctgt
     6961 gctactctca ctactcatgc ttcctgtgct actttcacta ctcgtactct ccgtactgct
     7021 ttcgctgctc gtgcttcctg tgctactttc actactcgta ctctccgtac tgctttcgct
     7081 gctcgtgttt tctgtgctac tttcactgct cgtactctct gtactgcttt caccgctcgt
     7141 gttttctgta ctgctttcac tacttgtgct atccgtactg cttggcggtc caacaactgt
     7201 ccaactgctt ggtttcaaat tctccgtgat cgtcatctgt ccatcataaa aaacaatcaa
     7261 atcaacttta tctttactct tgatctcatc aatcgatagt tctgcagaaa tcattattgt
     7321 atactcaata ccagcggtcc attgtacgtc ttttaaataa acttccccaa taactttttc
     7381 tgaacttcca ttaccatccc aaccatatgt tagaacagca tgtacatcac tagcattcac
     7441 gcttttgttt ggtttgactg gaatagtaat gacttgttgt gtcatgtcat aaacaatccg
     7501 atcagttttc acagtaaatg aaagattctc atttgcccgt tcatttgcag aagtactgat
     7561 tccaatcatt gctgcaatta tactcagccc aagaataaca aataatacgg tcgctgtttt
     7621 cttcatttct atcactctcc atataattac cttctatttg ataaaggaat tatataaaat
     7681 gaaaatgatg agaacacgac agtcagttgt gaaaatctaa caaaagatgt cgtgtattcg
     7741 cttgaatttg tttacttttt cgtttaatca atgacagact taaaaaagca agaccgatat
     7801 cagccttgct ttcttcatct tttattgata aacagcagtg tatttcttca tccgctttgt
     7861 tttatatgca tagagtaaca aaccaacaat caagactaac aagaataatg tagttgatat
     7921 agatgcttca gccccaaagt ttcccccagt aattattgta ttttgcgatt ggatcagagt
     7981 ggagaaaaaa ccttgttctt gcgttccgct gactggtata cccaaaatag ctccttgtgt
     8041 ccaattccaa gtaatatgag caccaatagc cgtaaataaa cttcctgtac tgtagataag
     8101 tgcgctgaaa aagcaacctg ctaaaaagat attgaaaact gccagaaatg tcatgttagg
     8161 attcaatccg tgcaaaagag caaataatgc agcagatcca atcattgcta ttaacggacc
     8221 aaatctaagc atctgatgct gaaaaaagcc acggaataaa agctcttctg atgcccccac
     8281 tgcaataaat aaaataaaac tcgttatcag cggcacaatg tttgcgtttc ctgaatctaa
     8341 ccgatacgcc cccgtcaaat ataatggact agtaataagc agaaacactc caattccaac
     8401 aacgagacct cccgctaaat acccccagtc ttttcctcga acagaaacac cataatcttc
     8461 tattcttttt ccttcgacct tactagcaag aaataaagct agtaaaaaaa cagctaaatg
     8521 tccgaccgta ccggcaattg ctccaatcca ttcactattt ccaataaaca tatccgcaag
     8581 tgcattattg acaagaattc ctaaaacaaa accaactaag actattaaaa cagatccaat
     8641 caaccgaata atcctgatca tctttcatcc ctcctttata ttaagtttaa caaccctttt
     8701 ctttcttgtc tcgtgaaaac tatgtaaatg ttctccatca tagagagaat agatttttac
     8761 gaactaagaa tatctacagc aaccttacga aaatgaaaga ctgtctccct aattcttctg
     8821 ttagactgtt tttaataagg aaaggatggg aaattttttg aaaaaacaac tactaattat
     8881 gtgcctttca gcatgtgcaa ttttactatt ctcaggttgt agcaagtcca atgaaacgat
     8941 tgcaacgttt aaaggtggaa cacttacagt tcaggatttt tatgataacc caaaagttaa
     9001 atcaaataat caaacactat taaaaaaaat gattgtcttc aaagcatttg atgatgtata
     9061 cggaaaagag atttcttcaa aggaagtaac aaaagaatat aatgaacaaa tcaaaaaact
     9121 cggtccaaac tacaaggaac aattaaaagc agttggccaa acagaagaga catataagaa
     9181 actctttaaa cagatgctgg ctttccaata cggtttgaaa gccaatgtaa aattaacaga
     9241 taaagatcta gacactgctt ggaaagaatt ctatccagaa gttagtacac agatcattct
     9301 attttcgact aaagaagaag cagataaagc aaaaaaagaa gcaaatgaag gagaaaattt
     9361 ctccaagctt gttcaagctt atggaaaaaa taaaacatta aaggaaactg atggaaaaat
     9421 gaattttgat tcaaccaatc cagagattcc tactgaagta aaaaaagcag catttaaact
     9481 aaaaaacggg gaagtttctg atatcattcc tgtaacagat ccaacgactt atcagcaaag
     9541 ctattatcta gtaaaaatgg taaaaaaaca ggataaaggt tctaataaag acaaatacaa
     9601 atctgagcta gaaaaaattg ctaccgaagc aaaaactctt gatacggaat tcatggataa
     9661 aacaatccgt aaagtgatga aaaaagacaa tgtaactatt aaagatcctt atgtaaaaaa
     9721 tatattcaaa taaacaaatt tgacccaatt ggg
//
LOCUS       DAXLPY010000083         9609 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.083, whole genome shotgun sequence.
ACCESSION   DAXLPY010000083 DAXLPY010000000
VERSION     DAXLPY010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.083"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            29..451
                     /locus_tag="ACF3UF_002341"
     CDS             29..451
                     /locus_tag="ACF3UF_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672414.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(617..1810)
                     /locus_tag="ACF3UF_002342"
     CDS             complement(617..1810)
                     /locus_tag="ACF3UF_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3672415.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            2034..2411
                     /locus_tag="ACF3UF_002343"
     CDS             2034..2411
                     /locus_tag="ACF3UF_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3672416.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2399..2737
                     /locus_tag="ACF3UF_002344"
     CDS             2399..2737
                     /locus_tag="ACF3UF_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3672417.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            2871..3314
                     /locus_tag="ACF3UF_002345"
     CDS             2871..3314
                     /locus_tag="ACF3UF_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HFD3672418.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            3576..4391
                     /locus_tag="ACF3UF_002346"
     CDS             3576..4391
                     /locus_tag="ACF3UF_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3672419.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            4401..5063
                     /locus_tag="ACF3UF_002347"
     CDS             4401..5063
                     /locus_tag="ACF3UF_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFD3672420.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            5268..6932
                     /gene="alsS"
                     /locus_tag="ACF3UF_002348"
     CDS             5268..6932
                     /gene="alsS"
                     /locus_tag="ACF3UF_002348"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFD3672421.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            6945..7655
                     /gene="budA"
                     /locus_tag="ACF3UF_002349"
     CDS             6945..7655
                     /gene="budA"
                     /locus_tag="ACF3UF_002349"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFD3672422.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            7785..8282
                     /locus_tag="ACF3UF_002350"
     CDS             7785..8282
                     /locus_tag="ACF3UF_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFD3672423.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANLNINAF
                     SFINN"
     gene            8467..8727
                     /locus_tag="ACF3UF_002351"
     CDS             8467..8727
                     /locus_tag="ACF3UF_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672424.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(9089..9328)
                     /locus_tag="ACF3UF_002352"
     CDS             complement(9089..9328)
                     /locus_tag="ACF3UF_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672425.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT         3254 a         1580 c         1917 g         2858 t
ORIGIN      
        1 tagtaaagta gatacaggag gagaaaatat gcagactttt ttaacaaaag tttctcaaaa
       61 gaaaattaaa atgattcatt tactgcttga aacagaacgt tggtgttcaa tagaagaact
      121 acaaaacgaa ttgaaggtat caagtaagtc tatcttgaat tatctaacag atttagaaga
      181 attgttccaa aaatatcctg ataaggtcat tttgaagaat gagaataatc ggcgcttttc
      241 tatggaaaag caggagaact tcccaatcta cattatttat cttcatttct acagaaaatc
      301 atataattat catttgattg aattcatgta tcaacatcct gagaaaaatt tggaagatta
      361 tgcagacgct caatatacga gtgtatccac agtttttcgt tatgctaagt tattagtaaa
      421 gtactttgaa atgacggacg tcaaagaata gtagccgcca gatagaagga aattagcagt
      481 tgaaaaagct gccctgcatc aagtaatacg accagccaaa cggaaacagt gtctcatgtt
      541 tttgatttgg ctggtcttat taccgcagat gcaagctttt gccacacctc tttcttgtca
      601 tttacagact caactatcaa tgctgcaagc tttcccttaa tgctgtaaca ccagtaagag
      661 ttgtcaagac cagcagactg actaggtaaa taccgctcaa aaacaagatt acggcagtta
      721 aactataatg atccatcaag aaaccgatga cgatagaaga aaaaccacca acagctcgtc
      781 caaggttcat aatgaaatta ttcgccgtcg cgcggatttc tgttggatac aaactactaa
      841 tcactgcgcc atatccacca tacatgccat tgataaagta gccgactatc acagcggctg
      901 ctaccaaact ccactggcta tgggctaaca caagtagata gacagataag gatgaacaaa
      961 ttaaaaacaa agaaaaggct agtttaggcc ccaatttatc catgattatg ccaaaagtca
     1021 tcatccccaa agacatgcct aaaatagtac tgaccatcca caatgaagac ccagaaaccg
     1081 aaagccctaa tcgattttgc ataattgaag gcagccaatt cattaaccca aaatagccgg
     1141 caatttggac agttaccatg atactaaggc cacatgtttg ccaagcaaga tgttttgatt
     1201 caaacagtct gctaagtttg gttttctttt cggcagattg tacagatttg aattcctttg
     1261 gttcagtcaa gccgcgacga atgaacaaga ccatcaacac cggcagtaca cctacgacat
     1321 acaacatctt ccaaccaaac gttggaatga tcacagcagc taaaatcgca gccaaagccg
     1381 caccgacctg cgcaccaata ccagcaaccg aagaagctcg tccaatttgt ttttttgaaa
     1441 aactttcgga aatcaaggac atacacgccc cgtattctcc tcccgctcct acacctgcga
     1501 taaagcgaaa gagataaacc aagtagatgt ttgaagcaaa atacatcaat aaagaagcaa
     1561 tcgaaaacag aaggaccgtt tgagaaaata ctttcacacg tccatattta tcagctatga
     1621 tgccaaaaaa aatacctcca atgagcatcc ccaaattagt gatcgttgaa atgaaacccg
     1681 cttgcgtacc actaatatga aaagaagtaa tcattgaaga taatgaaaaa gctaaaaaca
     1741 taatatccat attctctaaa gcaattcccg ccgatgtcga taataataac tttcgctgat
     1801 acgttgtcat ttttataccc cttttcctaa aatttcccta aattgttaaa agtatatcca
     1861 aaaaagaatt aaaaaacaag acttttttat ttgaaataat acacaaacaa ccgatataga
     1921 taatccagct tagttttaat agaaatgagt attgacttgg agtacactta aagttgtaga
     1981 ataaataaaa tacataagta aagtggcaag aaattaagag aaagagtgat cagatgaata
     2041 tcaaacaagt cagtgaagaa aagggcattt cggccgatac attgcgctat tatgaacgaa
     2101 tcgggttgat tccaccagtt aatcggacaa aaggcggaat ccgtgattat acagaagaag
     2161 acctaaaatg ggtcgacttt acgatctgta tgcgaaatgc cggattatcg atcgagtctt
     2221 tgattgaata tattcgccta tctagcgaag gagaagcaac tgtatttgag cggcgtaagc
     2281 ttttgattga agaaagtgaa cttttgacga aaaaaattgc tgaaatgcaa gaatgtttgg
     2341 aacgtttaca aggaaaaatc aagaaatatg atcgtgtgtt atctagaaat aaaatggaat
     2401 gtatcaagta aaaaaatcaa ggagcatcgc tatggagtta cgcttactaa aatatttttg
     2461 gacaattgca gaagaaggaa caatctctca agccgcagaa gttctacatc ttacacaacc
     2521 aaccttaagc cgacaactga aggagttaga agaggaacta ggaacagaac tgtttgtacg
     2581 cgaaaaccgc aaaatgatct tgacagaagc aggttatttt ctaaaaaagc cgagcagaag
     2641 aaattttaga tttaacgaat caaaccactc aagaattcga gaacagaaaa aaacaattat
     2701 tcagcggccg atttacgatc ggctgtgtgg aagctgataa ttcgaataca ttggcactat
     2761 tactagaaaa gttgatccgt gattatccca gcgttcaatt tcatatccac agcggaacaa
     2821 gtgatgatat cacggagtga ctagaaaaaa gcctgttaga tttagcgatt ttgctagatc
     2881 cagtagatac agagaaatac gaaacgattt tgttaccaag aaaggaaaaa tggggattgc
     2941 tcattttaga aaattctgtt ttagcaaaaa aagacgtgat aacaaaagaa gactttgcga
     3001 atgtacctct tttgatctca aagcgtccag aaatacagcg aatgtttgct gactggttag
     3061 gcataaaaaa ggagcagttg ctgatcacag gaacgtacaa tttgattttc aatgtatttg
     3121 cgctaattga gaatcaggta ggtgctgctt tagtcataga aggtgctgta agtcatcttt
     3181 caaagcgagt gacattcgtt ccgcttgacc caatgattga aacgaactgc atgctagtct
     3241 ggaaaaagaa tcggatttta tcacctgtag tcaatgaatt gattcaccgt ttcaaagaag
     3301 cttttgaaca gtaataagta tctctaatcg aagaaatttc aatacaaaag cgagacgtat
     3361 gacagtcttg cttttgtatt ttttcatttt taaatcaaaa aaaataaaga gatttacata
     3421 acttgttaaa taagcgctta caaacataag aagaacggaa atgaatcagc tataataacc
     3481 gttgttctgg attgtaatca ttacaaagaa atgaagatta taactttgga ggtgttcgaa
     3541 atgaaagaaa aaaagcaaaa attcgttcaa aaaacatgcc ctttattcaa tggttgggta
     3601 tgattctgct gattgtatta gctttattga cgatcattcc ttttttatgg atggtttctg
     3661 cttcattcaa agcaaataat gaagtgttca cgattccgat tcaatggatc cctaaaactt
     3721 ggcatttaga gaattatctg gttatttggt ctcgtattcc tttagtgaca ttttttaaga
     3781 atacagcttt tttaagcgtt gtgatcacgt tgattcagtt gtttacttct agttttgctg
     3841 cttacgggtt ttctaaacta aattttaaag ggcgcgatat tttattttta gcatatatcg
     3901 gcacgattgc tgtcccttgg cagtcttata tgatcccgca gttcattatg atgagaaaag
     3961 tgggtttaac atatacgttg tggtcgttgg tgctattaca agcgttcaat gcttttggtg
     4021 tgttcttgtt gaagcaatac tacagtagta tcccagattc tttatgtgag agtgcgcgga
     4081 tcgatggctt atcagagtgg ggaatctatc gcaagatcat tttacctctt acaaaaccgg
     4141 cgattgccag tttgacgatc atcacattcg ttaatacatg gaacgattat atggggccat
     4201 tcatttattt gtcttctacg gaaaataaaa caatccagtt agggttgaaa atgtttattg
     4261 ggctatttga tgcagagtac gcattaatca tggctgcctc agttgtttct gttcttcctg
     4321 ttgcttttat atttttagcg atgcaaaaat attttgtaga agggatcgct tcatcaggaa
     4381 tgaaggaata ggaggtgatt atgaaagagc agcgttttga caaaaatgtt tatatggaat
     4441 tcttttattg gttgtatcaa tcattggcaa gtagcctttg tttttggtgt gtcaatatct
     4501 tgtatatagc agctgcgttc cttttgtcga tagatggaag gaatgtcttt tcctttattt
     4561 tttctttact ttttattggt ccaggttgca tcgtgatgat aggtatgaca gaagaattag
     4621 caaaagaaaa aagtttttca ccagtacgtt tgttcataaa gacgtttcgc caattttggc
     4681 taaagggatt tttttattgg ctatttgctt ggatagttag tgtgataatg atttttgatt
     4741 gtttcttttt tatacgtttt tcttatggaa aatggttgat tccgttgttt gttttacttg
     4801 cttgtttatc agtttccttt agcatcaact actggtattt tcaggtgaga aatccagcgt
     4861 cgaaaccaaa tcaagttcta cggatagcgt tctactatac gttgaaaaaa tggtatgtga
     4921 gtttactaga ttttttacta ttgacaagtt tgtttctctt ctttttcgta aagccccaat
     4981 ggtgtattct actaggtcct tctatcgtat ttggtttgat ttacttcaac aatcgtaaat
     5041 tgatgagaac tatggatctg tagactttat aaattgaaac tttcaattaa gaatgacagt
     5101 ttttatgtaa aaactgtcat tctttttcat tttttgaaac atatggctaa acaaatgaaa
     5161 taaaacgtgc tatacttttg aatgaaacag gtttagaaac tgtatcaatt atttgtgatt
     5221 atttctaact aataattaaa aataaagcat aaaaaggacg atgttcaatg gacgaaaaaa
     5281 tgaaacaagg ttcgaaatct gtagtagaaa gtttgattaa tcatcatgtt gattatgtat
     5341 tcggtatacc aggtgcaaaa atcgatggtg tatttaatga attagaggat caaggtcctg
     5401 aattaatcgt gactcgtcac gaacaaaatg ctgcatttat ggcacaagca atcggacgta
     5461 ttacaggaga gccaggagta gttatcgcaa caagtggtcc tggtgctagt aacttagcta
     5521 caggtttggt aacagcgaca gcagaaggtg acccagtttt agcaattgcc ggacaagtaa
     5581 aacgaagcga tctattgaag ttgacccatc aaagcatgga taatgcagca ctgttccagc
     5641 caatcacaaa atacagtgca gaaatccaag atccagaaac aatttcagaa gtgattgcca
     5701 atgcttatcg tatggctaag agttcaaaaa aaggcgcgag ctttatcagt atcccgcaag
     5761 atgtagtgga tgcacctgtc caagggaatg tcatcaagcc attgagcgat cctaaattag
     5821 gttctgcttc tgcagatgat atccgttacc tagctgaacg cattagagaa gcaaaactac
     5881 cggtactatt agtaggtatg cgaggatcaa gtgaaaaaga aacgttagcc atcaggcaat
     5941 tagttggaaa gacagcattg cctgttgtag agacattcca agcagctgga gtgatctcac
     6001 gtgaattaga agcgcatttc tttggtcgtg tgggtttatt tagaaaccaa ccaggagata
     6061 tgcttttgaa acgaagtgat ctagttattg ctattggcta tgatccaatc gaatatgaag
     6121 caagaaactg gaatgcggaa aaagatgcgc ggatcattgt gatcgatgaa gcgccagctg
     6181 aaatcgatcc ttttatgcag cctgaaagag aattgatcgg tgatatctca gccactcttg
     6241 atttattgac aggttcatta gagcctcaac aagtgtcaga agatgcaaaa gaatatttag
     6301 catctcttca agcagaatta acggagcggg acattgttca atcaaaagga gaagcaggta
     6361 tcttgcatcc tttagaagtt attaacacgc ttcagtcaaa agtaacagat gatatgactg
     6421 ttaccgtaga tgtaggtagt cattatattt ggatggcacg ccactttaga agttatgaac
     6481 ctcgtcattt gttattcagt aatggtatgc aaacgcttgg tgttgcattg ccatgggcga
     6541 tttctgctgc attggtgcgt ccaaatacac aaatcgtatc agtttccggc gatgggggat
     6601 ttttattctc tgcccaggat ttagaaacgg cggtacgtaa aaaattgaat atcgttcatt
     6661 tgatttggaa tgatggacac tacaatatgg tagagttcca agaaaaaatg aaatatcagc
     6721 gggcgtcagg tgtagacttt ggtccagttg attttgtgaa atatgcagaa gcttttggcg
     6781 ctaaaggaat ccgagctaca agtgtagagg aattagaaaa agctttagaa gaaggatttg
     6841 cgacagaagg acccgtaatt attgatattc cgattgatta ccgtgataat gagaaattgg
     6901 gagaaacaat cttaccagat caattctatt aaggaagtgt cgacatgact gaaaaaatct
     6961 tataccagca cgggacatta ggagctttga tggctggctt gatggatgga acagaaacga
     7021 ttgctcatat attagaaaaa ggaactctgg gattgggaac attgcatggg cttgatggtg
     7081 aagtcatctt tttagatggc gtagcttatc aaggaagatc agatggctca gttgcccaat
     7141 tagatggaag tgaacttacc ccctatgcag caattacaga ttttacgcca gatactagtt
     7201 tttctgtctc aaaaactgca gatggagaac aattgaaaaa agacatatta gtaagagaag
     7261 ccggggaaaa cctatttttg gcagtgaaga taactggatt attcaaaaat atgcacatcc
     7321 gtatcatgcc gaagcaagaa aaaccttaca gaagactagc aaaaatttca gagtctcaac
     7381 cagaattcca acaaagcaat gtccaaggaa cattagtcgg gttctttacg cctgaattat
     7441 tccaaggagt tgctgcagcg ggatttcact tgcattttat cgatgataca catacatttg
     7501 gcggacatgt aatggatttt gaagtggctg aaggaaaagt tgagattagc cgcatctcgt
     7561 cccttgtaca gcattttcca gttgatgatc cgacttttgt tcacgaaacg attgattatg
     7621 ctgatttagc agcagaaatc caacaagcag aatagaaaaa gacagcgaga tgcgttcaag
     7681 gtgattaacc tgacgtatct cgtttttttg aggaggaaac ctagcgttta caaaaaaact
     7741 gagctataat cttctccata gatcaaaaag gagcggtttt tatcatgtgg acagaaaaac
     7801 agaaaaaaga tgcatacgaa attttattat tacagcaaca aggattatta gaagcagaag
     7861 ataactggtt agcaaattta gcaaattcat ctgcattgtt gaatgagact ttgcctgaga
     7921 ctgtctttgc aggatattat ttattcgatg gtaatgaatt gattttagga ccgttccaag
     7981 ggcgagtttc ttgcacacgt atcaagatgg gaaaaggagt ttgtggagaa tcagctgaaa
     8041 aacaagaaac attgatcgtt gatgatgtca aaacccatgc aaattacatt tcctgcgatt
     8101 cagccgcaca atcagaaatc gtagtgccaa tggtaaaaga aggtaattta atcggtgttt
     8161 tagatatcga ttgcggagta acgaaagggt atgatgaaat cgatcaagca tttctagaaa
     8221 aatatgtaga tcttttatta gcaaatttga atataaatgc tttttcattt attaataact
     8281 aaaatcgtct attgaaacaa aaaagaagag aaatcaagaa taaaaagagc cggaaagaca
     8341 gtgggcattt ctgtttttcg gtttttttat ttttttataa aatcacaagt gttattgatt
     8401 ttcataatca tattttaatg gtattatcat tttaaataat ggaaaaacat taaggatgga
     8461 tgaaatatga ataacgaaac tatcatttta ggaaaaaaat atatttgcca acctattggc
     8521 ttgaaacaaa aagtggttgg agaagtaatc agtaaattag aaaattgtgt tgtgatctgc
     8581 gtagacgaat atcatgacgt cgatcgcaat gaaatattag aaaaatgcgg aaaagtagtg
     8641 gcaaaatata ctcacgttta tgagttggaa acaacagaat atctatataa ctatagcaac
     8701 aaatatgaac atactttagt ttcataaaga tttaaataaa gtgccttcaa aagcgagaag
     8761 accaagcttt tgaaggcact ttatttagtt ggcagtgatt gttcatgatt tttgatttat
     8821 tcaaaaggtt cgcctagaga atctgtctct gtaacgaggc ctggtggaga aactcgataa
     8881 aaacctatac tgccagaact gtcctatttt cggatagaca aactagtagt tttaaaaaga
     8941 tcatccgatc caatcatttc aaaaaatgca aaactgatat caggatcatt tagctcaggc
     9001 ttgttatcgt aaagcatttg taaaggttgc atttagttag gagtaaacgc gaaactatca
     9061 tcattatttg ctgaagaaga tgaagaagct aattcagagt ttgtttgaaa taaaggagac
     9121 gtgctgacag tttctttacc ctgttttttg cagaggtaga aacttttata tcggaagttt
     9181 ctaccggaga atttttctca tttgtagaaa ttgttgaatc gatactattc gaaatttgcg
     9241 tatctgaagg tatgttcttt gatgcagaag tcccacaagc agtaagtaac aataaatttg
     9301 ataaactgat aaacagaatt cttttcatta tgtacacact ccttatagta tcgtttagca
     9361 tacacctatg ctcagtatta ggcaaaatca atgcaaaact atcaagtctt ttatagtatc
     9421 tattagtctt agtaatacat atatggagag ggtgatatcc cagttcaaac cagatacatt
     9481 ggttaccatc tgtattaacg attatgcctc taaacgcttt ttttatgaaa aaatttataa
     9541 gtgaaaacgt aggtatgata ttatctagag gtaatttttt tgggtattta aatagttgct
     9601 aggaggata
//
LOCUS       DAXLPY010000084         9001 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.084, whole genome shotgun sequence.
ACCESSION   DAXLPY010000084 DAXLPY010000000
VERSION     DAXLPY010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.084"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(1..270)
                     /gene="rpsN"
                     /locus_tag="ACF3UF_002353"
     CDS             complement(1..270)
                     /gene="rpsN"
                     /locus_tag="ACF3UF_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFD3672426.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(793..2559)
                     /locus_tag="ACF3UF_002354"
     CDS             complement(793..2559)
                     /locus_tag="ACF3UF_002354"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3672427.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(2519..4273)
                     /locus_tag="ACF3UF_002355"
     CDS             complement(2519..4273)
                     /locus_tag="ACF3UF_002355"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3672428.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(4383..4952)
                     /locus_tag="ACF3UF_002356"
     CDS             complement(4383..4952)
                     /locus_tag="ACF3UF_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFD3672429.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(4970..6385)
                     /locus_tag="ACF3UF_002357"
     CDS             complement(4970..6385)
                     /locus_tag="ACF3UF_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3672430.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(6396..7064)
                     /locus_tag="ACF3UF_002358"
     CDS             complement(6396..7064)
                     /locus_tag="ACF3UF_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFD3672431.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(7194..7778)
                     /locus_tag="ACF3UF_002359"
     CDS             complement(7194..7778)
                     /locus_tag="ACF3UF_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3672432.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(8109..8342)
                     /locus_tag="ACF3UF_002360"
     CDS             complement(8109..8342)
                     /locus_tag="ACF3UF_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFD3672433.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(8357..>9001)
                     /locus_tag="ACF3UF_002361"
     CDS             complement(8357..>9001)
                     /locus_tag="ACF3UF_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3672434.1"
                     /translation="GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPH
                     AWLNLENGIIYAKNIEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPND
                     KKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVES
                     SVDDRPMKTVSKDTNIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
BASE COUNT         2992 a         1650 c         1191 g         3168 t
ORIGIN      
        1 ttaccaactt gcttttttta ctccaggaat caacccttga tgggcaagtt ctctaaactt
       61 aatacgggac ataccgaact ttcgcatata ccctcttgga cgaccatccg tctgatcacg
      121 aagcctcaga cgattcggat ttgaatctct tggcaattta gcgagagcgg tgcgatctcc
      181 tgcggctttt aattcctgac gtttatctgc atacttttca atcatcgcca tttgtttctt
      241 tgctttagca attttcgact tttttgccat atacctttat actcctttta ttttgattta
      301 gacacctcaa atcgtaatcg ttacgttttg acactgatac tttaccaaca agagttgctc
      361 ttgtcaacaa taaataacat gaaataaaac tcatatgaat agataactat ttgaaaacga
      421 atttatcggt acatagagat aatcaaatca tttaaaagaa tatgcagttt aggctctgaa
      481 aaataagaat tcacttttat tagtccaatc aaacacaaat accgttttaa gtagcttttc
      541 ctctacttaa aacggcaata tgaaagaaac tataactttt tattcaatct tttatgttta
      601 actggtttat cgccaatttt ttaaaacttt gattattcct tatattataa gaatagacat
      661 taagtgaact aattcaatca tactgattct ttcgtgtatt caaaattaga tgctgtttaa
      721 taaaattatt ctttttgaaa aagaattata actatatccc aaaaattgta ggttaattta
      781 aagcctattt catcatcgtg attgagcttc tttttcatag acgaatttct cagatagttt
      841 agttttcttt atgagatttt tgtatatttc tgaccttcga tacaactcat tatgagtacc
      901 ttgatcaact agttttcctt gatccatcac tacaatttta tttacctttt caatagactt
      961 caagcgatgc gatataatta gtactgtctt atcttgtatt aaacgattta aactttcctg
     1021 aatacgtttt tcattttccg catctaaact ggcagtaatt tcatctaaaa ttaaaattgg
     1081 cgcatttttc aaaaaagccc gtgctatgga taggcgttgt cgctctcctc cagaaagtga
     1141 acttccgttt tctccgacca atgtatgata accgtcaggt agtttttcaa taaagtcttc
     1201 gcagttagct aaacgagctg cttttttcac ttcctcatct gacgcttgac tatttccaat
     1261 acgtatattt tccaaaatac ttgtattaaa caaagttacc tcttgaaaaa caatagcgat
     1321 tttgctaaac aaagaagctg gagatacacg tttaatatca tacccatcaa ttaaaataca
     1381 gccttcatca taatcataca gtctagacac taatttcaag atactagttt tcccggaacc
     1441 actagcacct actaacgcag tcacttctcc ttgtttagcc gtaaaagaga tatgatctaa
     1501 aattggggta ttgttatcat atgagaaaga gacatctcgc aactcaatgt caaaagattt
     1561 cagaggacta tctgatccct cttggatact ggtttccttc atagctctaa ttcgctgtat
     1621 tttaggagct aaataaaata tttcaagcac tgcttctttc atagaatcga aggaatcctt
     1681 tatttttatt gcggctagta agtaaccaac gacgtagagt atagtcactt cacccgttaa
     1741 cagtaagtga acacctacta gaatgactac tgctaaacta acatatgaga aaatagagga
     1801 taaggccatg actgaaaaag tacttaattc tacctttaaa tgaatccttt cactctcttc
     1861 catttttttg aaaagtctgt cttgaacttt tttagataga ttaaagctat taatctcttg
     1921 ctgcaattct atagtttctt gaaattcttc cgagttttct ctcaaagtat cgtaatattt
     1981 agtattggct ttcgtttggg atttctttga taacaagatt aagacaaaac taaataacgt
     2041 tggcaaaata acagctaatc ccattttgac attaccaacc aaaagcatca ctgaaataaa
     2101 agggaaaaac agagccatac cgccggcttt aggtattgca tgactcatcg catgctcaat
     2161 accttcaacg tcagacatga tagtttgaga taaatctgat aaattatgtt ttgaaaaata
     2221 ggataatggt aaatttgaca aatcgtctgc aatttgcact cttaaatgcg cactttcttt
     2281 ataagtacta ttatataagt tttcatactc cctatctaac aaccaataca tgaaaagcaa
     2341 agtaacaaac gatacggcaa aataaagcca acggggcttt gtattttcta aaactaattc
     2401 gtctatcagc atcattataa tgaatgctgg taccatatta atgcagtata caaaaaaact
     2461 agaaatagaa gctttagtta aagcttctgc gccctgatca cttaaagcaa atttgttttt
     2521 ataaaaactt ttcattgtca agcctccaat catttgcatt ctcataatta gtgaccaatt
     2581 gtttatacac ttgatgttta gccattaatt cattatgatt tccacgttct actattttcc
     2641 cttctgacaa gacaagaatt tcatctacag atttaatgct ggataatcga tgagctatca
     2701 taataactgt tttttctttt atcagatgtt gaaaagcctt ttgtagttca tactcattat
     2761 ctggatcaat agatgcactg gcttcatcca taataacaat ctttgcatct tttaaaattg
     2821 ctctggcaat agctatacgt tgtttttctc ctcctgacag ataaactcct ttactaccaa
     2881 ttaaggtatg ctctctttcg ggaaattttt ctaaaatcga ttcgcaaccg gctaatctta
     2941 gcgcgtcaaa tactttactt gctggcgctt gaggatttgc tatagaaacg ttatcgtaaa
     3001 tactctgatt gaatagtttc gtatcttgaa agacaaaagc aattgtgtta ataattgtgt
     3061 cttttgaata gtgatttaaa ggcttaccac caattttaat ctgtccctta tccacattgt
     3121 agaaacctga aattagttta gctatcgtac tctttccgct tcctgatttt cctactaatg
     3181 cataaattct tttttgttct aaaactaagt tgaaattttc taaaacacac tcttctttgt
     3241 atgaaaagct gacattttca aatgcaatgt cacaattttt aatctgtgtc tcgttcccat
     3301 attttagttg gtcttgcttc atttctaaat aaagggagtc tagtgtttcg actgcatatc
     3361 ttgcttcaaa caagtgcata cttacataca ttattctcat gaaagaaaca aaaataattc
     3421 cacttaaaaa aaacaacatc aacaagtcaa cagctaatat cttgggagtg gtaagagaag
     3481 ttataaaaaa ggttatagga actatcaaaa tgcaaactat gccaaaaaat agccattgaa
     3541 aaagaacaaa aggtgttttc ccactcaaag aatacttata tgcaaactta gcataatcgt
     3601 taattgcttt attcaaggct ttaaatgatg ttactttagc accaaatatc tttataactt
     3661 gaattccgcg gatatattct accgtttcag agcttaacac atctaacgat tcttgatatt
     3721 tttgaataaa atttgtattc tctgtcattt tctttaacaa gaatacacca attactaaca
     3781 tggcgattag aaccaatcca attttaaagt taatgaaaaa gcctaaggca actgataaaa
     3841 caggtgttac tatggcttga gcactatctg gaatcaagtg agcaattgcc atatgtgttt
     3901 tagccgcgtt gtcatcaatt gtctttcgaa tatatcccga agaatttaaa tcaaaaaaac
     3961 gaaaacttgc ttctgttaaa ccgctaattc ccttttttct caaattagtc tctaagcgaa
     4021 acccaaggat atgagaaaat aagccagaaa aaatataaaa taaagctcct aaagttaacc
     4081 aagcaacagt ttgaaccgca taactcttag ctaaatattc atctcctaca ataattagag
     4141 actgaagaaa tttgtaaata ctgtaatatc catagactgt taatacgaca gaaaaatcag
     4201 aaaataaagt ggctaaccat ccgtagtatt tcattttagg gacataacta aataattttt
     4261 tgtatacttt cattttttcc tcccccgcat tcaatttctt ctcttattcg tttacaactg
     4321 ttaatgcttt ccgtaatagc gtaaattaga gatgtacaaa cagataaaag gtaaactacg
     4381 ttctattttt tgtatttttt taagactttt cttccaatca atacaccaat catagataaa
     4441 cttgctacaa ctaacactga aatgattccc catataccta ccgcatagtg gatcattgca
     4501 tccattgttg cagcagattg tcctttatct atccaatctt gacgaaaacg atctgtaaag
     4561 aaccatatag gaatccactg tccggcagca ctgcctaatt gcattagagc ccaagacgca
     4621 acttgaggaa ttgctcgatc atatccaaat acagatagaa taatatcagc taagatcgcc
     4681 atactaatcg aactgataaa ccaaggtaag tacgccccgc ccattaacgt aaaaaataac
     4741 aataaaacaa ttgtgtaaat agtaaaaatt ccttttctag ggtagttata gctaatataa
     4801 acaaatatga ttccagataa taatccaaaa atcccggggg atatgctgtg accaaacgcc
     4861 ccaccaatac tactaaccat tattgaaaaa aagtaaatta ctagggaaat aactgtagct
     4921 aaaccaataa aaatataatc ttttgttttc atatatattc tcctcaattc tatttcgtta
     4981 tgtcattaaa aatctgttct atcaaagttg aatcttctac tctaagtttt atatcttttt
     5041 ttattccacc attttttaaa taaataattc tattgcatgt tttataaaga aattccggat
     5101 catgagtagc tataactact gcaccctttt cttttaagtc tttaataagg tcagcaatcc
     5161 tttccatatt aatataatcc aacccacttg taggttcatc aaatagaaat aaattagttt
     5221 ttgacaatga agctatagaa accaataatc tttgtttttc tccaccggat aaatcaaacg
     5281 gtaattgatc tttcatttta taaagttcca ttttttttaa aattttttct tgctgatctt
     5341 tactaactat ttcattcccc agggctaact cgctcctcac tgattctgtg aaaaattggt
     5401 aatccatttc ttgcattact aaaaacggcg atgacaaatt ttttttattt tcgattatct
     5461 ttcctttggt agggcgaata atcttcatga gtattcttag taaggttgtt ttccccacac
     5521 cgtttttccc taccaaacca ataacatctc caactttgac atcaaaattt atgtctttta
     5581 gaatattttc ataagtaatt tcttcaactt ttaatacatc tgcacttacc ttttcgatat
     5641 agggaacttc aatcgaacta ttaaaaatgt caaatttcct taatgcgtta ttgttttcag
     5701 tttttaacaa ctgaatagtt gtagttttta cagttctatt tttaacaaat agaacttgat
     5761 caattaattc tttcaaatag taaaaacgat gttcagctat aacaatagta aatcctttat
     5821 tttttaaatc acaaagtaag tcagcaagtt tcttagtcgc tttgaagtcc aaatttgaag
     5881 acggttcatc caatataatt aatttagagt ttagcgataa actacatcca atagaaattt
     5941 tctgccgttc accacttgat agcgaaaaaa tgtttttatc taatatattt gaaagatcta
     6001 ataattcagc taattcattg attcttttat ccatatgctc ttttgtaaat ccaaagtttt
     6061 ccatcgaaaa tactaactca ctcgttgtat ttgttgtaaa gaattgtcct ctaggatctt
     6121 gacttacgta gccaatattt tttgatatac tttcttgtgt taaggattgt agcgagttat
     6181 tttcaaataa aatttcccca accaattttc cgtcataaag tcttggaata agtccattca
     6241 ttaactttaa tagtgtggat ttcccactcc cagaagaacc agtaatcaat gtaagactgc
     6301 ctttttttat tgaaaaatta aggtcaacaa gcgcttgttc cttaacatcc ttatatgaaa
     6361 aagaaacatt gttaaattca aacaattctt tcacctcaaa tcaaaatact taagaaaaaa
     6421 atagtaacgg aaaacaggat gatatagtct aataagctca tgtttgtttt atagtaagaa
     6481 cttcttttca caggagattc tatccccttt gttattgcat tagcggtcat ttcttcagca
     6541 atcatagttg cacgtataag aacgggaact aacagaaatt ccaaatattg cagaggctga
     6601 aaaaaagaca agcgaatgtt tctcattttt aaagattctt taatcattct tatttcagaa
     6661 cgataagtcg gaaagaatct gatcactact gtaatactta acattatttt tttcggtaaa
     6721 tgtatttttt ctaaagagga taataattca ttgctagtat agacactaac caacaaccat
     6781 gagatcatta cgaccggcaa cattcgaaat acaatatata aggatgtcgc aaaaaatata
     6841 gtaaaaaact ctatcttgat agcatcaata attttcatta ctaaaaacag aactgaataa
     6901 atcaagatga aataaataca tgtctttatt ttacgaaaca tcaatactaa aactgtagca
     6961 ataatgaaac accccacttg aaatatattt ccctttccta aaaaaataat gaccggaaaa
     7021 aaaatattta aagtaatcaa ggttaacgga ttgatttttg acactctttc acctccaaaa
     7081 aataagatcg cactgttatc ttaagctgat aaaaatgcac cgttattcag ataacagtgc
     7141 gatcttatca aaaagcataa ctgagaacaa ttctcaatgc aagctttttt taattaactc
     7201 agtaattcaa tccacccagg aacagaaaat tgatacaatc ttctggttaa tagcatagtc
     7261 ttttcttttg aatagctatg cttcaatata tcatagaatg tagcgtagaa tgagtaaatg
     7321 tagaagtgga tttcttcttc attaaagact aaattttgat tgatcattcc gatagtcttt
     7381 aacttatcta gacaacagac tgtctttttc gtcacaaatg atgtaatttt ttcaacaata
     7441 tcttgatatt tggttccagc tgattggaat aaaatcaaat cgaatatacg tttattctca
     7501 aaaatataat taataaatgg atctaattca ttgaagttct ctctccaact tttctctata
     7561 tctatatttt ctaagtttaa gaggtatttg gtaaactctt cattatacat attaataagc
     7621 gcattaatat gcggctgaat aatttcttca aataacgctt ccttagaagt aaaatgttta
     7681 taaaaagcac ccgtagttac gcctgcggtc aggcacagtt gccttatctt agtttgctga
     7741 aatccttctt tttcaaaatg gcttagtcca ctttctatta acttttggtg agttataata
     7801 taatctctgg tttctatggg tacttcctcc taataagatg aattaacttt attatcttac
     7861 acaggacttg aagtttcaat cgttaacgtt tattactgaa ctcattcctt agagctaaac
     7921 taatgagaaa gagcagaata actgatacaa aaagcaatcc tacaagaatt aatagactca
     7981 tctaaatcat tcaccttttc taaaataatc cgagaaagat ttaaaaaaat tatatccagc
     8041 tattaggata agtcctatca taatcactcc aatagccatt ttcttatcct ccctaaaaat
     8101 aaagtctttt acttaaaacc ttttttgtaa tcgtcaataa attttttccc tttatcagtt
     8161 aattgaaatc ctatatctaa atagtcctca tatctaagtt tagccagcat ctcacttaca
     8221 gatgctggac taacacttag aacttttgct aaatcattat tttttaattt cttttttctt
     8281 tttgataatt cctgaattgc tagtaaataa attagtatag tagtcgtttt aatttgtacc
     8341 atacctaccc tccaaattat ttcgaaaggc cttcagcaat tttatccagg ttccatttca
     8401 tcatcgcata gtaactatca ccatcttgtc ctttttctgc aattgaatca gtaaaaatcg
     8461 ttgaatagat aggaatattg gtatcttttg atactgtttt cattggtcta tcatccacac
     8521 tgctttctac gaataaggag ggaacttttg ttgtgcgtaa tttttcaact aagtgtttta
     8581 tttgatctgg tgttccttct tcttcagtgt tgatttccca aatgtaagca gaaggcacat
     8641 tatacgcttt cgagaaatat ttaaagcatc cttcacttgt aacaatcatt tttttatcat
     8701 tcggaattga agcaaattta gatttagctt ctttgtctag agaatccaat ttttcaatat
     8761 acttatctag attttcttta tagaattttt tattatcagg atctttttcc gctaactgtt
     8821 tttcaatatt tttagcgtaa ataataccgt tttctaaatt taaccaagca tgaggatctt
     8881 ccttcccttt ctcactctga ccctctaagt aaataacatc tatgccatca cttgctgcaa
     8941 aatagtcttt gttttcctct ttgttcgcat ttttaactaa ttttgtaaac caagcatttc
     9001 c
//
LOCUS       DAXLPY010000085         8998 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.085, whole genome shotgun sequence.
ACCESSION   DAXLPY010000085 DAXLPY010000000
VERSION     DAXLPY010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.085"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(69..1208)
                     /locus_tag="ACF3UF_002362"
     CDS             complement(69..1208)
                     /locus_tag="ACF3UF_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFD3672435.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1607..2905)
                     /gene="eno"
                     /locus_tag="ACF3UF_002363"
     CDS             complement(1607..2905)
                     /gene="eno"
                     /locus_tag="ACF3UF_002363"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFD3672436.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(3021..3776)
                     /gene="tpiA"
                     /locus_tag="ACF3UF_002364"
     CDS             complement(3021..3776)
                     /gene="tpiA"
                     /locus_tag="ACF3UF_002364"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFD3672437.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3880..5070)
                     /gene="pgk"
                     /locus_tag="ACF3UF_002365"
     CDS             complement(3880..5070)
                     /gene="pgk"
                     /locus_tag="ACF3UF_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFD3672438.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5180..6181)
                     /gene="gap"
                     /locus_tag="ACF3UF_002366"
     CDS             complement(5180..6181)
                     /gene="gap"
                     /locus_tag="ACF3UF_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFD3672439.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6222..7313)
                     /locus_tag="ACF3UF_002367"
     CDS             complement(6222..7313)
                     /locus_tag="ACF3UF_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFD3672440.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(7462..8796)
                     /gene="rpoN"
                     /locus_tag="ACF3UF_002368"
     CDS             complement(7462..8796)
                     /gene="rpoN"
                     /locus_tag="ACF3UF_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFD3672441.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8856..8927
                     /locus_tag="ACF3UF_002369"
     tRNA            8856..8927
                     /locus_tag="ACF3UF_002369"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8889..8891,aa:Arg,seq:ccg)
BASE COUNT         2333 a         1905 c         1658 g         3102 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtttatta
       61 aaaaaatctt acgctaagta ggataaaata attccttgat atttttcgat catatccaaa
      121 taattatcga tttcaacata ctcatctact tgatgaggca aagtaacgac accaggccca
      181 aagacgacaa agtcgaagga atggttagct ttcgtaaatt cggctgcatc cgttgttgct
      241 gccgctccaa ctaaaggtaa tggctggctg aattgttgct gaatgcaatg aatcaaagga
      301 gaatctggat cagctttgac aggtattttg ttgtaatcga tcatcaattc caaatgatag
      361 tctgtctctt gattcaattc attgacgatt gattgcagca atgcaatgat tttatcattt
      421 gggtattctg gaatcgatcg aatgttccct tggagctgcg catggcttgg gatgctgttg
      481 acttgattcc cgccactgat caatgtaaca ttatggattg tttttcctag gacaggattc
      541 tcgattgttt cagcgaggtg attcatttca gcatttgctt tcgtaatgaa ttcatttagg
      601 tgattgattg cattataacc ttggtctggc atagagctat gcgcttcttt tccgtgcgag
      661 gtgactgtat agttgattga tcccatgtgc gtatacatca aactgtaatt ggttggctct
      721 ccgatgatca aggcatctaa gtcatctaca tagcctgctt tcgtgagctg ttccccacct
      781 agttcaccca cttcttctcc gacagtggct aataatttga ctgttccgtt aaatggtttt
      841 cctgactctt tcagttcgat catggcaatc accattgctg ccaagccact cttcatatct
      901 gtagcaccac gtccgtacaa acggttccca tggatttctg ctgcaaaggg tgcataggtc
      961 caagacgatt catcaccagc cgccacgaca tccatatgcc cagataggcc taacactttt
     1021 cctgattggc ccttttggta acgagcaatc aaattatctc taccatctct gtaagaaaca
     1081 atctctcctg ttatgtcatg ctttgccaaa agcttattca aataggctgc tacttcacct
     1141 tcgtttccat tcactgattt aattcggata atctcttgta aaatcgcgat tttttcttct
     1201 tttttcatct aatcctctcc cttgccattt ctttttattg tatttgagtg tgctcgaatt
     1261 ttcaaatagg agcaaccaaa gtaaaaatga agaaagagag ccactttatg aaaaatatgc
     1321 tgctacttcc ctcctatttt atttatacga gaggacttgc ccatagattc ctattctact
     1381 gttctatcct taaaagctct tatatgatgc tagttattgt tagctttcct ttttcaagga
     1441 tgatcttttc ttgtaccatt ctttgtaaac atcatataca gaagctagtt gcaaaaaaac
     1501 tctctacctg ctgatatttc agcaagtaga gagttcgatt acttaactaa gtgatcatac
     1561 tcgactatct ttcaatagtc gatcatgtat cttcattaga aaagaattat ttgtttttta
     1621 agttgtagaa agatttcaaa cctttgtatt ctgcaacttc accaagttgg tcttcgatac
     1681 gtagtaattg gttgtattta gcaatacggt cagtacgtga tagagaacca gttttgattt
     1741 ggccagcgtt tgttgcaaca gcgatatcag agattgttga atcttctgtt tcaccagaac
     1801 ggtgagatac aactgctgtg tagccagctt ctttagccat ttcgatagct tcgaaagttt
     1861 ctgttaatgt accgatttgg ttcactttga taaggattga gttagcaatt cctttttcga
     1921 taccttcaga taatttttga gtgtttgtta cgaacaagtc gtcaccaact aattgaactt
     1981 tgtcgcctaa tacgtcagtt aatttcttga atccgtccca gtcgttttcg tctaatccat
     2041 cttcgattga gatgattgga tatttagaaa ctaattcttc gtagaatttg atcatttcgt
     2101 cagttgtttt ttcgccttcg cctgagtcag ctagtacgta aacacctttt tctttgtcgt
     2161 agaattctga agaagcagca tccatagcaa gaacaacgtc tttaccaggt acatagccag
     2221 ctttttcgat tgcttcgatg attacttcaa aaccttcttc gtttgaacca aggtttggag
     2281 caaatccacc ttcgtcacca acagaagttg ctaatccgcg agctttcaag attgaagcta
     2341 atgcgtggaa tacttcagca cccatacgta gagcttcttt gaatgttgga gcgccaacag
     2401 gcatgatcat gaattcttgg aagtcgattg agttatcagc atgtgatccg ccgttgatga
     2461 tgttcatcat tggtgttggc aatacttttg tgttgaatcc gcctaggtag tggtataaag
     2521 gtacttctag gtagtcagca gctgcacgtg caacagcgat agaaacacct aaaatagcgt
     2581 tcgcacctaa tttacctttg ttaggagttc cgtctaaagc gatcatagct ttgtcgatag
     2641 ccatttggtc acgaacatcg tagccaatga ttgcttcagc aatgatgttg tttacgttgt
     2701 cgacagcttt agttacacct ttaccgccat aacgagcttt gtctccgtca cgtaattcaa
     2761 ctgcttcgta ttcaccagtt gaagcacctg aaggaaccat tccgcggcca aaagctccgc
     2821 tttctgtgta tacttctact tcgattgttg ggttaccacg tgagtctaag atctcgcgag
     2881 cgtaaacatc agtaataatt gacatgtttt gtctctcctt tgagtttgtt ttttcctaag
     2941 ggatttccct catatacgat tttagttaat tttgctcatt agtgcaaaca tttcttgcat
     3001 ttttcgcaaa ttttcaacaa ttattttaca gcgtctaaca atgacaagaa tgaatctgct
     3061 tgcaagcttg cgccaccgac taaagcaccg tcaacatttt cttttgccat gtattcagca
     3121 atattttctg gttttacaga accgccgtat tggatacgaa ctgcttctga tacttctttt
     3181 ccataaagtt tttcaactgt ttgacgtaca actccacaaa tttcgtcagc gatttgtgcg
     3241 tcagctgatt taccagtacc gattgcccag attggttcat aagcaataac catgtttgac
     3301 acctgttcag ctgaaagatc agctaaacca gctgtaattt gtccttcgat ccattcagca
     3361 gttttgcctg cttcataggt ttctaaagat tcgccgcagc ataggattgg tgtcatacca
     3421 tttgcaaaga tagctttcgc ttttttattg atgtcttcgt ctgtttcatg gaaatattca
     3481 cgacgttctg aatgtccgat gatcacataa tgaacaccta gatcagcaag agctgctggt
     3541 gaagtttcac cagtgaacgc acctgagttt tcccagtagc agttttgtgc tgagattttt
     3601 agttctgtac cttcagctga tgtcattaat tcttgtaaga ataatgcagg agatccgatg
     3661 actgaatcaa ctttgtcatt tgaagggatt ttgtttttta ctgcttcagc aaattctttt
     3721 gcttctgatg cagttttgtt cattttccag ttacctgcga taataggttt acgcattgag
     3781 gaacacactc cttaatttat tgaaaaatgg ctagggagtc atgaaaactc ccttcacctt
     3841 ttgttcgatt actcgtcaga attgagcaaa cttggtcgtt tatttatcgt tgattgctgc
     3901 tagtcctggt aattctttac cttcaagcaa ttccaagctt gcgccgccac ctgttgagat
     3961 gtgtgtgaat ttgtcagcaa atcctaattg ttctgctgct gcggctgagt ctccgccacc
     4021 gatgattgtt gttgcgcctt ctaagttagc gattgcttca caaacaccga ttgtaccttt
     4081 agcaaagtta ctcatttcaa atacacccat aggtccgttc caaacaactg tttttgcacc
     4141 ttgtaatgta tcagcaaata attttactga tgctgggccg atgtctaaag ccatcaaacc
     4201 atcaggaatg tctccttcga ttacttgtgt ttcaacatca tttgaaaatt ctggtgcaca
     4261 gacattgtcg attggcaaga caagtttgtc gcctgctttt tcgattaatt cttttgctag
     4321 ttccacttta tcagcttcta ctagagagtt accgatcttg attccttttg cttcgtagaa
     4381 tgtgtaagtc attccgccac cgatcaagat tttatctgct ttaggaatca agttttcgat
     4441 tacgccgatt ttatcagaaa cttttgcgcc accaaggatt gcaatcattg gtcgttttgg
     4501 ttcttctact gcttcaccga tgaacttgat ttctttttcc atcaagaatc cagcaactgt
     4561 tgggatacca gttgaagcga tacctacgtt agaagcatgt gcacggtgag ctgtaccgaa
     4621 agcatcgtta acaaatacat cgcctaatga agcccagtat ttacctagtt ctgtatcatt
     4681 tttgctttct tttttaccgt caatatcttc aaatcgtgta ttttcgaata cgacaacgtc
     4741 gccgtcattc atgttgcgga ttgcttcttc taattgttct ccgcgagttt caggtacgaa
     4801 tgttacttct ttacctaata attcgcctag acgttttgca actggagcta aagattttcc
     4861 ttctttatct tcttctgttt ttacacgtcc aaggtgagag aaaaggattg cttttccgcc
     4921 ttgttctaga acgtagttga ttgttggcaa tgctgctttg atacgagtgt cgtcagtgat
     4981 cacgccgtct ttcaaaggaa cgttgaagtc aacacggaca agaacttttt tgtcttttaa
     5041 atcgatatct ttcactgttt tcttagccat tttatttcct cctgaataaa cttattatca
     5101 aaaaaagcgg aagaagcgcg attgcttccc cgcttttaaa tgtacatgtc tataatttac
     5161 acttgtacgt ttgtctatct tataagttag cgaagtattc taaagtacgt actaattgtg
     5221 cagtgtatga catttcgttg tcgtaccaag caacagtttt aactaattgt ttgtcgccaa
     5281 ctgtcattac tttagtttgt gtagcatcaa ataatgaacc gtaagtcata ccaacgatat
     5341 ctgaagaaac gatttcgtct gtgttgtatc cgtaagattc gtttgaagct tctttcattg
     5401 ctgcattgat ttcgtcaaca gttacttctt tttcaagaac tgttactaat tctgttaatg
     5461 aacctgttgg tacaggaaca cgttgagcag ctccgtctaa tttaccgttc aattcgggaa
     5521 ttactaaacc gatagcttta gcagcacctg ttgagttagg aacgatgttt gcagcagcag
     5581 cgcgtgcacg gcggaagtca cctttaggat gaggtccgtc tagagtcatt tggtcacctg
     5641 tgtaagcgtg gatagttgtc attaatcctt caacaacacc aaatttgtcg ttcaatgttt
     5701 tagccatagg agctaaacag ttagtagtac atgaagcacc tgagataact gtttctttac
     5761 cagttaatgt ttcgtggttt gtgttataaa cgattgttgg aacatcgttt ccgccaggag
     5821 cagagataac aacgcgttta gcaccagctg ttaaatgttt ttcagctgct gatttagaag
     5881 tgaagaaacc agtacattct agaacgatat ctacgcctag ttcgccccat ggtaattctt
     5941 ctgggttgcg gttagctaat actttaactt cttttccgtt tacgttgaat gaaccttcat
     6001 gaacttcaac tgttccgttg aaacgtcctt gagttgtgtc gtattttaac aagtgtgcca
     6061 acattttagc atctgtcaag tcgttgattg ctactacttc gattccatct acatcttgga
     6121 tacgacggaa tgctagacgt ccaatacgtc caaaaccatt aatacctact ttaactgtca
     6181 tttaagattt cctccttatg aaaatcaaaa aaatatttat tttaaagggt tacccctttt
     6241 aaaatctcat ttgcagcagc ttcatcagtg atgagccacg tttgttttgg tgcatttttc
     6301 atataagctc gaattgcttt agcttttgat tttccgcccg cgattgccat gatgatcggg
     6361 actttttcca aatcttgcaa ttctatgccg attctaggga ccttataaac gacttcacct
     6421 ttttcattga aaaagtagcc aaaagattcc gcaacagcat ttgcttgttt cagcatgact
     6481 aattcttttt cagtcatctt acgacgtgct gccatgtgta atgcacgccc aatactatga
     6541 ataacacaat tcgcttcact aatcaagttt aagacttctt ggatagatgg ctcattgagt
     6601 aaagaattgt aagttgccag acttaattgt tccggaacat aaagtgcgcg gtggttaccg
     6661 tttgctttag cagccattct tgcactgaca gaatttgcct gtacagttat cgcttcacca
     6721 atcccgcctc ttgcagggac aaacaggtta tgccgtttct tattttccag attagacaat
     6781 tgttcggcta ccacagccat agtagttcct cccatcacag cgatgatatt ctcgccttct
     6841 ggaagtagtc ggtctaaggc ttcgctcagc gcttcgccga atgcatcagc cactttggtc
     6901 tgctcttcgc tgtttcctga aacaacgata cagcgttggt taccaaaata ttctgccaac
     6961 tgttgttcgg tttgatgcgt acctaaaagc tgatccatga agttttcaag gctttgataa
     7021 acttcttcgc ccttagttgt cagcgtcata ccgctttttg aggtgtcgat caaattcaga
     7081 tttttcaaaa ggtctgtttc tgttcgtaag actcgttctg tgatccccat actttccgat
     7141 aaacttcgac gcccaatcgg ctgcatccaa tagatatttc gtaaaatttt atagcgttct
     7201 tgcaacactt cgataatatc tggtgcaaca gattcaatca tttttatttc atccagcata
     7261 gcgatctcct tagttggaca ctttacgtcc aatgtagact taaaacgacc catatacgat
     7321 aaaaaaagaa attaactatt cgaatttcac atcaataaag ggaaatctca acctcacgac
     7381 tgtaagtcta acagttttgc tctcgttttt caactaaaaa gactagaaaa agtgaaatac
     7441 tttttctagt cttttgactg attagttatc ataacgtttt ctttttgatg aactcgggat
     7501 tcctaataaa tcacgatatt ttgctactgt tcgtcttgag atcgctatct catctttttt
     7561 cagcaattca accaatttct ggtcagacaa cggcttgttt ttgtcttctt gatcgactaa
     7621 ttcctgcagc tttttcttcg ctgtatctgc tgaaaggtct tctgtctgtt ctgtactatt
     7681 cgtaggaatt cgtgtagtga aaaatttttt taattcaaat acaccgaagt ctgtttccaa
     7741 atatttcccg ttgactgcac gactgaccgt ggattcatgc acatctatct cagttgcaac
     7801 ttcctttaac gtaagaggct tgattggacg ttccttgtcg ataaagaaag ctttttgccg
     7861 ggaaacaatg acttgagcaa cccgcaaaat tgtatcccca cgttgtagga tcgttttctt
     7921 caaccattcg aattcctgtt tccgttcttt taaataattt tcagtttctt tatctgcttg
     7981 ttgtgacatt tgtttgaagt aactctcttg aaagcgtata tttggctgat tttttcggtt
     8041 tgagataact tgtacatttt tatcgtcgtc cactaatacc cggacatcag gaataatgta
     8101 caattcgctg ctacggtcga aaatccggcc agggcttgga ctcaacgttt gtaaatagtc
     8161 gaatatctgc tgaacagcat gtagatcaac agaaaaacgt tgtgcgattt ctttccattt
     8221 tcgctccacc agttcctcaa aacattcttc caacacgata taagctaatt ccggcgcata
     8281 atcatctcgt tctgtttgaa gcatgagaca ttcttgcaaa ctacgtgcac ctactccagc
     8341 tggttctaat tgctgaatca gagtcaacgc atcgagcatt tggataggcg tagctccaat
     8401 ctcttttccg gcttcttcta aactaatcgt caaaaatccg ttcaaatcga tgtattctac
     8461 aagataaaga acgattttcc tcaaaaaagt atctcggtaa ttcaaatgga cttgttcgat
     8521 caatgaatca aataaagacc cttttgtatc aggaatctga tttaggtaat ttgtctcttc
     8581 tccttcataa gaagatgaag aagcttttat gtaatctggc tgccattccg gctcaacaac
     8641 ttccaccaat ggattttcca ttgcttgatt ctcaacgaat gccaacagct cctcactgtt
     8701 atattgtaaa acttggatgg actgttgcaa ctgttgcgtc atggctagtt tctgtgtctg
     8761 ctgctgtttt tgtgaaaaat tttgctcaaa tttcattttt ttgtccaatc cccttgtaat
     8821 tttttatctg tttagttaca attatcccag tgcttgcgtc cttagtgtag tggatatcac
     8881 gtaagattcc ggttcttgag acgggggttc gattccctca ggacgcgttc tactgctatt
     8941 ttagcataat ttacgaatag ttgcttcttt atttttaagt gaaaactgtc cgccaaag
//
LOCUS       DAXLPY010000086         8948 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.087, whole genome shotgun sequence.
ACCESSION   DAXLPY010000086 DAXLPY010000000
VERSION     DAXLPY010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.087"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            157..690
                     /locus_tag="ACF3UF_002370"
     CDS             157..690
                     /locus_tag="ACF3UF_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672442.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(816..1493)
                     /gene="nth"
                     /locus_tag="ACF3UF_002371"
     CDS             complement(816..1493)
                     /gene="nth"
                     /locus_tag="ACF3UF_002371"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFD3672443.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1500..2198)
                     /locus_tag="ACF3UF_002372"
     CDS             complement(1500..2198)
                     /locus_tag="ACF3UF_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFD3672444.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2466..3650
                     /locus_tag="ACF3UF_002373"
     CDS             2466..3650
                     /locus_tag="ACF3UF_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFD3672445.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3656..4099)
                     /locus_tag="ACF3UF_002374"
     CDS             complement(3656..4099)
                     /locus_tag="ACF3UF_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFD3672446.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(4325..4612)
                     /locus_tag="ACF3UF_002375"
     CDS             complement(4325..4612)
                     /locus_tag="ACF3UF_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFD3672447.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            complement(4783..6135)
                     /locus_tag="ACF3UF_002376"
     CDS             complement(4783..6135)
                     /locus_tag="ACF3UF_002376"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFD3672448.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            complement(6407..6853)
                     /locus_tag="ACF3UF_002377"
     CDS             complement(6407..6853)
                     /locus_tag="ACF3UF_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFD3672449.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            complement(7089..8015)
                     /gene="cysK"
                     /locus_tag="ACF3UF_002378"
     CDS             complement(7089..8015)
                     /gene="cysK"
                     /locus_tag="ACF3UF_002378"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFD3672450.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            complement(8155..8948)
                     /locus_tag="ACF3UF_002379"
                     /pseudo
     CDS             complement(8155..8948)
                     /locus_tag="ACF3UF_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
BASE COUNT         2455 a         1808 c         1459 g         3226 t
ORIGIN      
        1 tagcttaaaa attagaaaat ccatttttct tttatcatta catatacttt atccatttac
       61 ttgtttataa ttaaatcggc taaatacaca ctagtctttt atttagtgcc acttcttaat
      121 aatcccattg ttattatcaa ataaaaaata caatatatgg ttttgaataa ttttttgaaa
      181 gaaggcttca ttttgagtta tctgatagta tgcttaatta tcataatttg tctgcaccat
      241 ctttttttat cgaaaacaat acctcgttat tccaagaata aaaaagctga aaaattttgt
      301 ttattattaa ataaatttac tttaattgct cctatccttg catttattat tttttctgta
      361 cttttaagca ctactcttaa aggaaaattt atggaaagaa gctctcatgc aatgattctc
      421 acttttttat ggttgttgtt caccagaatc tatatttttc tgatgagcct gaaaccgccc
      481 aaatccatta gtttatgttt agttataaat ggtatttttt tattatcact tatcattttt
      541 attacacctt tagatagata cgtcacttat ttatataatc ctttggaata ctggacttat
      601 tttataggta tattggaagg cattattttc tacatcgggt attttcccaa taaaaataac
      661 aacttttatt tttatcgcaa taaattgtaa taagttacca tcctagctac tgagtatgta
      721 catttacttt ttcatgcaaa aaagataaac gaaacagctt ttctccataa taacaagata
      781 attcatacat ttatttgcaa ttaaagaaac cacgtctaca ggcgtggttt cttttttagc
      841 gccttttctt ttagacgcat ccgatttttc ccatcttgac atattgatag caaaggacat
      901 acctcgcact tgggatttct tgccgtgcaa tgatatctac caaaaaaaat cagtgtatga
      961 tgtgtcttta cccataattc ttgtggtact ttccgcatca gtgtttcttc tacttccatg
     1021 accgtagcat ctagtttgca gatcctcagg cgttttgaga cacgttccac gtgggtatct
     1081 actgcgattg ctggtatccc gaatgcatcc cccaatacga catttgctgt ctttctgcct
     1141 acaccaggaa gagacatcaa ttcttctctt gacgttggca cttgcccatc gaaacgttca
     1201 atcagctgct gtgcacacgc tttgatgttt tttgctttat ttcgatacaa accaatcgtt
     1261 tttattttaa gaatgatttc atcgattgaa gcttctgcta acgcatcggg tgtcggaaaa
     1321 gaggcaaaca aatctggcgt tgctttattc actgatacat ctgtcgcctg ggcacttaag
     1381 atcactgcaa tcaataactc aaatggatta ttgtgcttga gttctccatg tgcttcggga
     1441 aacattccat acatcgtttc tagagcttcc attgtttttt gtttgcttaa catattccgc
     1501 tactcctcca accaattttt cagtgagact ttcggcaatt cttcttgttg agctgactgt
     1561 tctacttctc tttgaagaag ctgctgtttt cttcgttttt ggtcttcttc cacttgttgt
     1621 tttgtacgta gattttttct ttcccacgat agcaaaatgc ggtcaacgta attaaaacta
     1681 taagcctgat ttaatacggc ttcccgcagt gctagcttca aaatttccgg ctgataatgg
     1741 tcttcttcta gccattgtcc gatccgctgg aactcgatcg aagaaagcgg gcgtccaaat
     1801 tcttgttcaa ataattgata cactgactgg atttcttttt cttgtgtttt ttcttcgtat
     1861 tttttttctt gtgtttttaa atactcacct aatagatcat agatggggta aagattatat
     1921 cgatctgctt ttttaccgtt gacaatcgtc gtttctatct tgataaatcc atttgttacg
     1981 agacgatcca gtatttgaaa aatctgatct tgtttgattc ccatatccat agcaatcatc
     2041 tgcaaatcag ggaaagtatc tccttcaagc tgtgccatat gcaactgtag aacaaataaa
     2101 aattcttcag attgtagacc gatcctatga taatttttaa gtaaaagatt agatatgact
     2161 gtttgtccag cgcttaagta attttctaaa ttcaacatga tttctcctcc gctcaatcac
     2221 agtatacgta aaaaaaacat gggaagcaag aacaggtttc ttttctattt acttcactga
     2281 tcggtcagat ttacaatgtc gtctacttga tttttgtttg ttcatgtttt tgatgcgtat
     2341 cttcactttt cggaataaat aaattaagta gatttcgctg ttccttagaa tgttgacaag
     2401 gaaacaaaat tactatacac tatttttgtt tccaagttaa cattattgca taaaggagtt
     2461 tttacatgta cagtttcaca aataaacatt ctaaagtttt tggatacgtc tctgtcttat
     2521 tcactggatt aggatttact atcgtcagtc ctgtacttcc gtttttaacg ctgccttatt
     2581 ctcactccat acatcagcaa gctttctata tcactttgct catgtctgtt tatgctctag
     2641 ctgccttctt atctgccccc attctcggta gcttaagtga tcattttggg cgtcatccga
     2701 tccttattat cagtttatta ggatcaagta tcggatattt gctttttggt ttaggaaatt
     2761 cgatatggat gttgttcctt ggtcgtatca ttgaaggatt gacggcagga gaaatctcca
     2821 ccttatatgc ttactttgcc gacatcacgg aacctaatga aagaaccaaa gtttttggat
     2881 ggatgggtgc tttagtcggt ataggaacaa cgctgggtcc tattataggg ggtctattag
     2941 ctgagttggg gaattctgtt cctatattta ttggagcact ctttactttc ttaaatgccg
     3001 tttatggcta cacatttatg ctagaaagcc ttccaataaa aaaacgttca gtagatttaa
     3061 gtttctccca tgtaagacct tttcaccaat tacaacaatt attcaagatt tcatccgtta
     3121 ttcctttatt gacagcaggt tttgctgttt ggttggcagc tggctctctt caatctatct
     3181 tttctcaatt ttcgattgac gcctttcagt ggaaggctgg gttggttggt ttaagcttct
     3241 ctttgattgg aatcttggat actgtctcgc aattgttcat tatgcctcga ttgctcaaaa
     3301 aattttcaga acagcagatc acaagaatag ggatgttcag tgaaatcctc gcctatctat
     3361 tcatcacatt atctggaatt cttctactgc cgattttgtt tttatttggg attatctgtt
     3421 atggtttcgg tgattctatt tttactcctg tattcaatgg ccaactatcc aattctgtct
     3481 cagataacca gcaaggtctt gtaatgggcg gtacccaaag tatacaatct ctatcgcgcg
     3541 tcatcggccc gctaatcgca ggacagcttt atgctgcagc accatttctt ccgacggtat
     3601 tcggattttt gcttatgatt tttgcctatt atcactacaa taaaaaatag tagcttcatt
     3661 tgctacttcg tataaattct ctgtatcgac cgataaaacg aaatactgtg tcaaattctt
     3721 cttttgacat attttcaaat acagtagcat ctcgctgtac ccatttttga tggagttgct
     3781 cgtgtctatt ccttattttt tgtccgattg gcgtcaattg aaaatagatt tcttttttat
     3841 tctcttcgct ttgataagtg tttatgatcc ctctagctat cagttttttt gttagcttac
     3901 tgatggctcc tctagtcatg taactagcat tcgctaattt tgtcacgtta ggatcaggga
     3961 ttttcccgat atgttcaatc acttctagtt catttagagt aaatcctgca aattcttttt
     4021 ccatttctgg tttattacga tgaataatct cattagctaa atccagatat tcttctatta
     4081 gcagttgtct tttatccatt tctacacctt ctttttcttt cattatattg tttttttgtt
     4141 tcctattcaa caaagataaa aatattttgt aggaaaaccc aatctgaaac caagaaaaaa
     4201 aggggttgac aaagcttgtc ataacccctt tttctgatta aaagatagta aagagacagt
     4261 catcggtaat tgtgatgatt ttttgtcatc acttaaggat gagcggcctt ttcaaaaact
     4321 gtctttaaag atcatcatca gtttctagca catatggctg accttcatat gtgtactctg
     4381 tattcaatgt gccgtcattt tcatctgagt agatgcgtct actgaaagga aaacgatgag
     4441 aaacattatc tttggcgtca tttgctggca tcgtgtaata ttcctcttgc gtttcattca
     4501 actgagagag tacttgatct gccaactcat caatattgat cgttaatttc ttcgaagcac
     4561 ttttataatc ttctaaaaat gcatcttgtt ggacaaaata ttctttattc atcttctttc
     4621 tcacctttct tttcaaaatc aaataaagct gcttgttctt ttatgtaaca gctttatctt
     4681 tgctgcttat tgtgacaaaa aattcgaaga aagacaacta attgtacttt tcacaaaaaa
     4741 agacagaggg tcgtgacaaa attgtgtcac aacccttttt ctttattgtg cagtttcgat
     4801 ttcgcctagc gcttcttgtg caagtaggtt caagtaattc catgggcggt caaaatgtgg
     4861 ttggaagaag aaatctgaaa gtgcgagatc ttctacagtc attttatttt gaacagctaa
     4921 agacatggta tttgctgatt gtgtaatgtc gtatttggac atgaactgag cacctacgat
     4981 acgattcgtt cctttttcat agactagctc catcattact ttttcagtag ttggcatgaa
     5041 ctctggacga taattatctt caaatacagt cgcttggact tctagatcgt tcaaagttgc
     5101 gctttctttg gtcacacctg tcgaaccgat cgtccagcca aataggtaaa gtcctgaagt
     5161 tccttgagta ccacgatacg ccattttatg atctgtcaag ttatttccca caagtaaacc
     5221 ttgacgaacg gcatttgttg ccaaaggaat atagttttgc gtgccacttg gattgtagtt
     5281 gactactgca gagtctccag ctgcaaaaat gtctggatca cttgtctgca tgtattcatt
     5341 cactttgatt gccccgtttg gcagtgtatc tacttttcct tcgatcagtt ttgtatttgg
     5401 acggaagccc acacataaaa tgaccatatc tgtatcaaat gtatctgttg gtgtagctac
     5461 ttgtttcact tttccttctt catctgtgat aaattcagta acattttcgc ctagcgcaag
     5521 agtaacaccg cggtctgtca attctttttc taagatatct gtgaatggtt tatctagata
     5581 tttattcaag atgcgatcta atccatcaat caatgtcact tgttttccag attcgacaaa
     5641 agcttctact aattcaatac cgatatatcc accaccaaca attactacac gttttgcttc
     5701 tttcgcttgt gcaataattt catttgcttg attgtagttt ttgcatagga gtacattttt
     5761 cgcatcgatt ccactaatcg gtgggataat aggccatgaa ccagttgtca tcactaattt
     5821 atcataagaa accgtttctg tttctcctgt tttcagatct tttgccgtta ctgttttatt
     5881 ttctgtatcg acgtctgtta catcgtgttc cattttaact gttgctccta atgaagataa
     5941 ttcttcagga tttgagtaga acaagcctgc tgggtccttt actactccgc cgacataaag
     6001 tgcgataccg caagataaga aagaaatatt gtcatttctt tcatatactg tcacttctgc
     6061 ttctggatga ttttttaaaa tactttttac agctgcagta cctgcatgag tacagccaat
     6121 tactactact ttcatttatg gtccctccga ttaacatttt gtccttcgac aaaactacta
     6181 taacagaaat aaaacggata caacagttta atgcttgtga attcacaaag gtttgtttgt
     6241 agtttcattc cttttcaagc ataagaaccc aatatctaca agattcttat tgtgataata
     6301 ttcactttga tatctaagat tgtgaataaa agacaaaaaa ataaaaaagc tagcgttttt
     6361 ttacacagct agcttttttt aggtataaca cttatagaaa ctgtttttac atttgcgcct
     6421 tttttgctga ctctttacaa tccggacaga gtccatacaa ttccaaccga tgttcattaa
     6481 tctcaaaatc agtcagtctg ctcgcagcca tttctatatc ttcaagccct gggtaatgaa
     6541 aatcaacaat cttaccgcag ttttcacaaa ttacatgata atgacgcttt gaactgaaat
     6601 caaatcggct agaagcatcg ccgtacttca tttcttgaac aaatccaatc gaagtaaata
     6661 agcgaaggtt attgtaaaca gtcgcaacac tcatatttgg aaaccgatgt tcaagtgctt
     6721 tataaatctc atcagccgtt ggatgggaat gatgttcaat caaatattct aaaaccgcgt
     6781 accgttgagg tgtgattcga atgttctctt tttttaactt ttcgataacc tcttcgacta
     6841 acttattttc catgtaaaca ccccacgttg ttattctcgt cttatcatac tatttttaca
     6901 ttttaaaatc cacttaacat gaaaagaaaa ttcaatttta ttgtatttta atgaaaaaag
     6961 acgtaaaaca gtcgcgttca ctattttacg tctctattca aataattttt ctcatcataa
     7021 atttttgtgt gttcttttca tctttaaaag ttttttacat aaacctatct ggagaaaaac
     7081 caagtgcctt atatctcttg gtaaagggct gtagataaat aacgttcacc attgtcggga
     7141 accacagcta ataccttctt gccttttcct aattcttttg cgacttttag cgcggcagca
     7201 attgcagcgc cagatgagat gcctactaaa atcccttctt ttcgcccaac ttctctagct
     7261 gtttccatcg cttcgtctcc actaatagaa aggactttat catacacaga agtatccagt
     7321 gttttaggaa caaaacctgt accgattcct tggattttgt gaggtcccgc ttctttccct
     7381 tctaaaatag cagattctgc tggttctacc ccgattaatt cgattttcgg atacacacgt
     7441 tttaattctc ggccagcgcc agtgatcgtt cctcctgtac cgatacctgc aacaaacgcg
     7501 tccaagccat ttactccaaa tgcttgatgt atctcaggac cagtcgtctt ctcatgcaca
     7561 agaggatttg cttcattttc aaattgtaat ggtaaaaagt agccgttttc ttttgccaaa
     7621 cgttctgctt ctctgattga tccagaaata ccatccgcac caggagtcaa aatcaactct
     7681 gcgccgtacc ctttcatcaa taaacgtctt tcgatactca tcgtctcagg catcacgatg
     7741 attactttat atccttttgc aactcctacc atcgacaatc cgattcctgt atttccagaa
     7801 gtaggttcaa tgatagtatc acctggtttc agtagaccat cgtgttctgc tttttctatc
     7861 atacttaaag caatacgatc ttttacactt cctcctggat taaaaaactc aagctttaca
     7921 aaaacatctg ctgaatcttc tggtacgatt ttatttaatt tgacgattgg cgttttgcca
     7981 atcaattcgg tgactgagtt atagatagct gtcatcttca attcctcctt gtctttgctc
     8041 ttcttactta tcataataca atctgttcat ttatggcgag tgattcgtct ttgactagca
     8101 aaaaaaagac aaagatatac catatatggt agtttctttg cctttttatc taaatcaaac
     8161 gtttagttct tgaccaacta ataaagaata actggacata gacatgccat ttttcgccat
     8221 tagatcatca acagacatgc caaatttttg tgcaatatcc catagcgtat cacctgacac
     8281 gactgtatat gtctgaccat tatttgtatt tacatctgtt gttgaagatg atgacgttga
     8341 agtcgtcgta gtagtcgttg ttgttgtact tgtggtagcc gaacctgttg atggcgtatc
     8401 aaaacgggtt aaattataag tattaatcaa tgagttcaat ttggccccat aatttggatc
     8461 ggtagcataa cgacctgtca agtacgctgt tgcatcataa aaacttgttg tattgctttt
     8521 ccacacgcca gcataatgat aatcgcccgt ggaaaaactg gttgaacgaa gaacattcgc
     8581 atggtcttgg aaggattccc aataagaaga atattttcgg aatggttcat tcatcgttac
     8641 ccattgtccg ttacatattc tttggttgcc atataaacga cctgtccgtt atagcttcct
     8701 ttcacaccga atagattata atttggcgca ctagctaatc cggaagtgcc atatgcactt
     8761 tccaacaacg cttgagcgat catgactgaa gcatacaagt cattacttgc agcaacttct
     8821 gacgcagacc agccgatttg atcgataaac gcttgaggat cagcaactgt ttgagatcct
     8881 tgttcatctg catgaacatg ttgcggtacc gctgtaacca tcatcggccc aactaaaaga
     8941 ctcgttcc
//
LOCUS       DAXLPY010000087         8888 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.088, whole genome shotgun sequence.
ACCESSION   DAXLPY010000087 DAXLPY010000000
VERSION     DAXLPY010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.088"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(154..552)
                     /locus_tag="ACF3UF_002380"
     CDS             complement(154..552)
                     /locus_tag="ACF3UF_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFD3672451.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(549..1322)
                     /locus_tag="ACF3UF_002381"
     CDS             complement(549..1322)
                     /locus_tag="ACF3UF_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFD3672452.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1319..2002)
                     /locus_tag="ACF3UF_002382"
     CDS             complement(1319..2002)
                     /locus_tag="ACF3UF_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFD3672453.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2169..3056)
                     /locus_tag="ACF3UF_002383"
     CDS             complement(2169..3056)
                     /locus_tag="ACF3UF_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3672454.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3053..3922)
                     /locus_tag="ACF3UF_002384"
     CDS             complement(3053..3922)
                     /locus_tag="ACF3UF_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3672455.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4059..5345)
                     /locus_tag="ACF3UF_002385"
     CDS             complement(4059..5345)
                     /locus_tag="ACF3UF_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3672456.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5618..6196
                     /locus_tag="ACF3UF_002386"
     CDS             5618..6196
                     /locus_tag="ACF3UF_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3672457.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6196..7125
                     /locus_tag="ACF3UF_002387"
     CDS             6196..7125
                     /locus_tag="ACF3UF_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672458.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7122..8858
                     /locus_tag="ACF3UF_002388"
     CDS             7122..8858
                     /locus_tag="ACF3UF_002388"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3672459.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
BASE COUNT         2825 a         1881 c         1501 g         2681 t
ORIGIN      
        1 tagcatattt tgaaaagaaa gtctgatgct tagagtagaa tttcataaaa atttactatt
       61 tcataagtat tcacgagaaa aatacaaaca aaaaagcgga aataacgctc atccgccttc
      121 ttgtttgtgt ttatttcctc ttcaaacgct tgtctatgat tcagactttt ctctatcgtt
      181 attttcatct aaaagttctt gcattccgat aatttctcga tattgatgaa tcttagtgat
      241 accaatgact ttgtctacat caatactaaa acaaatacca ttacctggaa tatcgatgtt
      301 gatgccttga ccaatcgcat ccattacttt attcgtcaaa ctatcgggta ctaatgtcaa
      361 cacaatatct ttttctggcg aaatgtccaa acctaaaaat ttccctgaat catgtacacc
      421 agaacctctt ccatgtaaga tcgttccgcc tgctgcacct gcttcttttg aaaagtcgat
      481 aacatcttcg cccattcctc cgtcaacgat cgtcacaatc atgtgaagat tcaatgctac
      541 aagatctttc atttgctttc ccccaatttt tgcaatcttt ctttttcgat tctgtctttt
      601 tcatcttttc gtttataaat atatcctagt actaaagtgg ataatattgg tgtcaatgca
      661 atcattgcaa ccacaccaaa cccgtcaatg atcggatctc ttccttcaat ttgtgcagcg
      721 attgccacgc tcattgataa aataaatgtc gaacacatcg ggcccgttgc tactccaccg
      781 ttatcaaaag ccattgctaa aaagatcttg tccacttttc gtcctaaaat aaatgctagc
      841 ccgtatcctg ggatcaagaa ataataaaga gagaatccga cgagcaaacg ccacatagac
      901 aatcctactg ctgcgccgat cccaattgaa attaccatca gcatgatttt cgatcggatt
      961 ctcccctcgc tcaattcttc aacctgtttg atcattacat gaatcgccgg ctcagcaaac
     1021 cctactaaga accccattaa aaagccaagg ggaaccagta tataattgta aggcaatccc
     1081 gcaatagcac tgcctaaatg ctgtcctacc ggtacataag ccatattgac tccgtgcagg
     1141 aaaaggatca acccaatagt cgttatcaag aaacctttca taatgtcaaa gaaacgcttt
     1201 ttgcgcatac gaaaactaat gatattcatt aaaacaaata ggattacgat aggtgccact
     1261 gccaaaatga cttccatggt aacgatttcg attccatcta tcacttgctg ccagaaactc
     1321 attggaagat cacccccaaa atcatcacgg caagaatcgg ccctaacgaa gcaataccga
     1381 ccattccaaa actgtcattt tcatttttct tttgtttgat catactagtc atccctccgg
     1441 caagggccaa gataaatgga acagttactg gaccagtagt cactcccccc gaatcaaaag
     1501 caatcggcat aaattcggaa ctggtgaaaa atgaggcgat caaaacgcct atgtagccta
     1561 tagccatcaa ttgataatag gatagcttga atacgacccg aagcagcgca aaggctagaa
     1621 atactccagt gccgacgctg acgatcccaa tcagcaacac tctgccaatc tctccgtcag
     1681 atatatcata tacttgttgt cccaaaactt gcacggaagg ttcagcaatc gtgatcacga
     1741 tcccgatagc aaatcccaaa ctgaccaaaa cggtcaaact tttctttttg atcatatatt
     1801 tccctactag atctccgact tccatcatag aataatctgc tccaaacaaa aagagcgtca
     1861 ttccgatcat catgattgcc gcaccaacca gaaatgaagc gaggtcttct ccttctaacg
     1921 gtgcaaaaac aaacgttaaa atgacaatca ggacagtcat cggcaatata gcagcaatca
     1981 cttctttaaa attttttagc atgtatcctc ctcctttact ctttaagttt accttaaaat
     2041 gaaagagttt tcgagcacaa acttaaaacg ttatcattta atttttctca acataaaata
     2101 acacacgtcc caaaagtatc tttttacttg gaaaaatgac tttgaaggaa cgcgcttatt
     2161 gtgttttttt attttacaga gccgatcatt ccttgaacga attgcttttg caaaacaaaa
     2221 aatacgatgg cagttggtaa agtagcgatg actaatccag ccatgatcat tccatagtct
     2281 ggtgtatagg aagcacccat agcagataaa acaagcggaa ccgtccgttt atcaggagat
     2341 tgcaaagcta ctaagggcca taaataattg ttccagctac tcatgaatgt gatgattgca
     2401 gccgcggcat aggtattttt agccgtcggc atatacactc taaaaaaaat acttagttct
     2461 tttagaccgt ctaatcgagc ggcttctact agatcttttg gaaaagattt aacattttgt
     2521 cgaaagaaga agatcaaaaa agcagtgcta acagatggca ggatgacaac caagaaactg
     2581 ttgattccca aaaccgttcc gttcaattgt gaaaacattc gatataaagg gatcatcaat
     2641 gccgcaaaag gaaccatcat cgatagcagt agaatattga aaattaggtc ttttcgttta
     2701 ctttgataaa tctcaaatcc atatcctgcc attgacgaaa tcagcaatgc aaacacagtg
     2761 gtcaccaaag cgatcatcgc tgaattccaa agggaacgag taaaattcag ctcattggaa
     2821 aacaaatttt gaaaattgat gatcaagtta ctgccaatct ttatttttcc cgatgtgata
     2881 tccacgggtg tattcgtcat tcccaaaacc atccagacaa aagggaaaat ggaaataaat
     2941 gataggatgc ttaatgctgt atactttaat actgacccaa ttgtcgaacg aagttctaat
     3001 gcttgttttt tgacgttggg gcgttcgatt gtttcttttt ctaccatatt tttcatcgac
     3061 tttctcctcc tactttcgtt tggattatcg acaatatcac aataaaggaa acaataacaa
     3121 aggaaactgc tgccgcatat ccaaaattag gcgtgaattt ataactcaaa ttatagatgt
     3181 attgagatag ggtggtcgtt gcatttgctg gtcccccgcc agtaatattt tgtacttcat
     3241 caaaaagctg caatgtcccg atcgtcgaag taatggaagt aaacaaaatg attggtttta
     3301 aatttgggat cgtcactttg ataaactgct gccatttaga agcaccgtca atagatgctg
     3361 cttcataaat ctccgaatca atattttgca tgcctgaaag gaaaaaaatc atattgtatc
     3421 cagtccaacg ccaagtgatc gaaagaatga tcagaactct cgcccaaatt ggatgagtca
     3481 accagccaat cggtgtgtca atcataccaa tgcccaacaa caagttgttt acaaggccag
     3541 attgagaaaa tagacttttc atgatcagag aataactgac catcgaagtg atacatggaa
     3601 gaaagatagc ggttcgaaac aaccctttat atttcaactt tttatcattt aaaaggttgg
     3661 aaataaaaag tgctagaaac aacatgatcg gtacttgtac aagtaaatac aggaatgtat
     3721 taaaaaaagc ttttttaaaa gttgcatctg tcaacatccg ctgataatta cctaacccgt
     3781 taaatgtcat attgacaggg ggaccacttt gaaaagacgt gatcaaagcc aaaaccatcg
     3841 gaataaaaac catgattgat atcaaaatga ctggcaagat taaaaaagca tgcccgtttt
     3901 tgaataaatc tttctgcttc attcttttcc ctccaattct atcattgatt atctacatga
     3961 aaagacaaga aagacaatat ctgtaaggca gacgtgatct tttttgtctt ttcgtttgtc
     4021 tgatgaaaaa gcgaagaaat tcactttttt accaccgatc aattagccaa ttgtgcttct
     4081 acttgttttt gtgtatctgc tagtaccttg tctgtctctt ctccattgat gattcgatga
     4141 agagcttcag ctacgactgc ttcaattgca taggtctcat gtccgtaatt cacttctggt
     4201 atttcagatg tccatgttga aaaatcgtca aagatctttt gaccactgta aaattcagaa
     4261 gcttcttgat aagcttcttg ttcattcgcg ctaagcatcg tagatactag tccgatttct
     4321 ttcgcaagag tgcccatcag ttcttcattc gaagcaaacg ttgcttctag gaaatctttc
     4381 gctgaatctt ctccagctac tcctttgatc acataccagc cagcgccgcc aaggttagaa
     4441 gcttgcgctt tttgcagatt ttctggaagt gcaggtattg gtgcaatctt ccattttcca
     4501 gattggtttt ctgctccttg gatcgttgaa gaataccaag cgccagttgg gctagaagct
     4561 actgctcctg attgtatcgc agttactcca gcattccagt cagaggtttg ttcgactaga
     4621 tcttctttca aaagagtggc aaacaattca agaccatact ttaaagatgc attgtcttgg
     4681 atcgtgactg tctccccatc ttcagatgta taccattctc ctgcctgttg cataatcatc
     4741 cttactcgac caaggtcaga aggattgact tcagcgattt tctttcccgt cttttctttg
     4801 acatctcgcg ctacttgaat atactcgtcc cacttcagat tctccatatc ctcttctgta
     4861 taacctgctt ctgccatcag atccgtacga tagaagtttg ctgttacgcc cgaatcgaaa
     4921 ggaacaccgt atattttatc tcctactttg tttaccgcaa atttatacgg tgcaaaatga
     4981 tcttccttta caatagcaga caaattagcg aatgcatctg gataagaagt caaatagcct
     5041 tgtatcctat aatcttcaat caagacgata ttgggcaatc cttctgtatt cccgctcgct
     5101 aaagcggtgt tcagtttctg aacgatatca tcctgagaca tcgtaacaac ttctatctct
     5161 gtttcttcgt tctcataaac tttttttgct tcattcactg ctttgatatt gaatgtctca
     5221 tcccacgccc agacagtgac tttttcttct ttgtctgctg tactactagc acttccgcat
     5281 cctgttaaga aacctgatgc tgccgctaaa caaacgactc cagcaattaa ctttctgatg
     5341 ttcattttta tccgctcctt ttccatccat tagttgttta cgtttgctac attcatcata
     5401 ccaaaatttg aaaacggttt ctttattatt cagatacttc aaaaatttct cctaaaataa
     5461 taaaaaaata caaatcaact atgacaaaag gaataatctt agcatctaga ccaaagatcg
     5521 aaatggtgag gtttctttaa aataaaaata tccttgcatt ttctcctaga aataagtatt
     5581 tttaaattac aagactattc ttaaggcggg taaaaaaatg ccaatacgcg taattcttat
     5641 cgatgatgaa cagacgattt tagatggaat gaaacagttg atcaattggt ctgagcacgg
     5701 gtttcaatta atagggactt tttccagtcc gctgaaagcg cttgattttt ctttggtaca
     5761 tgcaatcgat atcgtggtca cagatgtaat gatgcctgaa ttaaatggaa tcgaattatc
     5821 gcggctatta aaacagcaac aacctgaaac acagatcctt atcctctcta gctatgatga
     5881 atttgatatg gttaaagatt cttttaaaga aggcgtcgct gattatcttt taaagcctcg
     5941 attgagtcct gatttttttc taaattcctt aactgccgtt tcacaaaaaa tcaaaaaaaa
     6001 gcccaacaaa agcccaatca ccaatcgtta tgagcagatc tgcgagaatc tttcacagca
     6061 gattgctgga caaactcgtc cattgcttga ccctcttctt tttgaacaca ccttgttttt
     6121 ctgttatata ccgaaaaacg gccattcagt tcaaaacaag gctctaaaca aaaacagtcg
     6181 atcacccatt cattgatgga tagcgacgat tcgtttacta tttatcctgt ttctaccttt
     6241 tcggaagaat ccggctatgt aatcaatact gattccaaag atacacttag gaagtttgtt
     6301 caaaagtttc gtcaagaagt ttttccaggt gatttttttg ttgtttctga ttcttttgca
     6361 atccaagata tcaatgaaat attccaagag atcagaaatt gcaccaaagg acaacgtttc
     6421 tatcataagg gaaagaacct tgcttatcag catgaacttc ttccgttatt aaccaaccac
     6481 gagcagcaag caagtagtta tttaacaaaa atcgttcata aagactacgc tttagctgtc
     6541 aaagaacttg agaatttctt cacgacgata ttggaacagc ctattgatcc agcttatttg
     6601 aaacatgagg caatcaatcg tttctatgca ttactcaacg ctttggctga cgagcatgtt
     6661 gggaatgaag aactttcttt gctcaagatc gcccttcctt ctttattagc cgatgctgag
     6721 tatttcgaag atttttctat tcttgtcaaa gaaacacttg agaaactcac ccacttttct
     6781 gcaaatgcaa aaaaagacaa tttcgatatc ttgactttga tctacgagtt cgtccaggaa
     6841 aattatgaga aagaaatcaa tttacaactt ttatccgaaa aatatcattt ttcatatagc
     6901 tatctctcag ccatctttac tgaaaaattt ggtatcaact tttcaaaata tctaaaaaaa
     6961 gtccgtatca gtaaagccaa gctctttttg acggaaacac ggcttacttt gacggaaatc
     7021 tgtgagaaag tcggctatac cgaactgggt tatttctcca gagtttttaa agaagagaca
     7081 ggaatgacac cttctcaata ccgtaaagga acttttgtaa aatgagaaaa aaaatcaaag
     7141 agcatgaact ctttgccaaa cttctgttca ttttgttcat cggtcttttt ctgcaagcca
     7201 tcgtcatttc tttgtttatt tatcatcgat caagggatgc ctatatccag ctgttcaatc
     7261 aatcgaatga tgtggtacta aaaaagattc aatctgaatt tgaaagtttg aatgatacaa
     7321 tcgagaatac attagccgct tttgattcta atccagctgt caaaagctat ttttccaatg
     7381 atccagccca acatatggaa cagcttcagc aactaagaac aatccaaaaa atgaatgact
     7441 ctctttcaaa aatccatcca atgatcgatt acgatgtatt gatctttgga gaaaatggaa
     7501 gaacttttgt cggaaacgac atgctcactg ccgtatctgc cgattctttt tttcaatctg
     7561 cgattgctca gagagtgaat gaacgtgctg ctgatacaca aatgcttttt gcacaccacg
     7621 gattgactct tcgcgataag aaagcaccca gcgtcttctt tgtcaaaaaa ctgaaaaata
     7681 cattgaatca cgtttacgga tatgctgttt tatcgatctc atccaagcaa ctagcgaatc
     7741 tttttcaatc tgtagtaaat cctgagatat cgaagatctc cttcatgaac gaagaacaga
     7801 cgatcatcgc atcaaatgaa gaaaatacaa ttgggagccg atcaatgatt ttcaaaaaac
     7861 taacagtagg tgaaacaacg atttcaaatg gacagcagtt gacccgtctt cctctgtacc
     7921 gccaggattg tacattactc agtcaagtcg atcttcattc tttatctaac caaatgggcg
     7981 tgatttttcc gattattttg tataatatcg tgacacttgc ttttgctggc tcattggtat
     8041 ttatgtattt ggatcgacac acaaaatcga tctaccgctt gattgattcg ctaaaacggc
     8101 tagaggaaga tggcttaaaa gctactgttc ctgtacaagg aagccatgaa gtccaattgc
     8161 tagggaatac gatcaatcaa ttgctaagta atgctcagca tcattatgaa cagacgatcc
     8221 aagacgaaaa gaagaaacgt tcgcttgaaa tccaaactat gcaagcacag atacagcccc
     8281 attttattta taatacgctg actagcttga aatttttgat ttggcagaaa aaaacagatg
     8341 aagcagttca aggaatcgac agtttcatta ctttactaag aagtacgatt gggaaaaaag
     8401 aagaagtgat tccagtcaag gaagaaatca aaagcgtaca aagttacatc gatcttttga
     8461 gtatgcgata tggcgaaaga atctcggcta aaataatgat tcctgatgaa ctgcagtcat
     8521 tatctatgcc gaatatgatc cttcaaccaa ttatcgaaaa cgcctatctt catgcttttc
     8581 acaataaaac gcaaggattc atcacggtgt acggcaaaac aaaaaatcag cttcttttat
     8641 tcgaagtgat tgataacggc gatggcttcg atactgaaaa taccaaacaa aaaaatgatc
     8701 atttttcagg aatcggcatc agccatgtag atgagcggat acgcctaatg tatggcgatg
     8761 catatggctt aacgatccaa tcagtgattg ggacaggaac gactgtaacg atttgtctac
     8821 cgcttcttcc taaaaatcaa tcagaatatc aaaaataaag aatagccaag cgctgatttt
     8881 tttatttt
//
LOCUS       DAXLPY010000088         8704 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.089, whole genome shotgun sequence.
ACCESSION   DAXLPY010000088 DAXLPY010000000
VERSION     DAXLPY010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.089"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..1416
                     /locus_tag="ACF3UF_002389"
     CDS             <1..1416
                     /locus_tag="ACF3UF_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFD3672460.1"
                     /translation="KEQKQTVKNEPVSKEQMQSKETKTKQKGYQKRTAEEIKQEVKSL
                     SQQALDAVKKHTHSPEDVKELLNFMSRFPERSFRNQLLIEEQFPGATACLGRAALKKE
                     GIYIKKGEQGNKIFVRKTVKGFYEKGRGFVRETEATPEDKKRIESGQIEVIKKPYYTI
                     EKVFDITQTQLKPEDYPKIFPNRVFDFQLDKKGQSELQAGIQAVANNIGIQIRDMTES
                     EVYQRELGQARGAYVRNEFTGEEEIVMNTRNTLTQHLATSIHELAHARMHKFSELDTA
                     TKELQAEMTSYIVCKHFGMDTSEKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVA
                     NEFIQTISNEINQYREREPEIQPAEVKQEHKNTVETAENKNIVPVGSLWIDKKDGKVM
                     EEDTGRTLHLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNPFRFSLETVS
                     EVAKRKNEIYYEQQLSQKERV"
     gene            1477..2937
                     /locus_tag="ACF3UF_002390"
     CDS             1477..2937
                     /locus_tag="ACF3UF_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFD3672461.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQERE"
     gene            2948..5152
                     /locus_tag="ACF3UF_002391"
     CDS             2948..5152
                     /locus_tag="ACF3UF_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HFD3672462.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            5168..5317
                     /locus_tag="ACF3UF_002392"
     CDS             5168..5317
                     /locus_tag="ACF3UF_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672463.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            5393..5986
                     /locus_tag="ACF3UF_002393"
     CDS             5393..5986
                     /locus_tag="ACF3UF_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFD3672464.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            5999..6898
                     /locus_tag="ACF3UF_002394"
     CDS             5999..6898
                     /locus_tag="ACF3UF_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFD3672465.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            6901..7386
                     /gene="ssb"
                     /locus_tag="ACF3UF_002395"
     CDS             6901..7386
                     /gene="ssb"
                     /locus_tag="ACF3UF_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFD3672466.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(7527..7631)
                     /locus_tag="ACF3UF_002396"
     CDS             complement(7527..7631)
                     /locus_tag="ACF3UF_002396"
                     /inference="COORDINATES: protein motif:HMM:NF028245.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFD3672467.1"
                     /translation="MPVETALGLMISFGSLIATIIFGILAVVNNNQKK"
     gene            7805..8065
                     /locus_tag="ACF3UF_002397"
     CDS             7805..8065
                     /locus_tag="ACF3UF_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672468.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            8502..>8704
                     /locus_tag="ACF3UF_002398"
     CDS             8502..>8704
                     /locus_tag="ACF3UF_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFD3672469.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
BASE COUNT         3241 a         1493 c         1796 g         2174 t
ORIGIN      
        1 aaggaacaaa aacaaacggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
       61 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taagcaagaa
      121 gtcaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
      181 gacgtgaaag aacttttgaa ttttatgtct cgttttccag aacgatcctt tagaaatcaa
      241 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc tgcgttgaaa
      301 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
      361 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
      421 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctacacgatt
      481 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
      541 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
      601 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
      661 tatcaaagag aattaggaca agcacggggg gcgtatgttc gtaacgaatt tactggcgaa
      721 gaagaaatcg tcatgaatac tcgaaatact cttacgcagc atttagctac aagtattcat
      781 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
      841 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac ttcggagaaa
      901 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagcg
      961 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1021 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     1081 aagcaggagc ataaaaatac tgtagaaacg gcagagaata agaatattgt gcccgttggt
     1141 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     1201 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
     1261 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaatttgc gctaggaaat
     1321 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
     1381 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
     1441 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa aatgagtctt
     1501 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     1561 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     1621 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     1681 ctttttttca tagacaaaga gatccaagac tctaagcaac aatttaaagc agccacagat
     1741 tttattctaa agaatgaaga caaaacagaa cgagtagaaa atcttcattt tgagacagaa
     1801 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     1861 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     1921 gccgaactaa agccaaaaca tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     1981 catgcggtcg cctttttatg gaaagatcca cagacaaatg agacagtagg ggcgagttat
     2041 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     2101 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagttaaaa
     2161 ttttttgaga gtagtattga tttacttagc tatgctgcac taaatcgtga tcagttaaac
     2221 gatacgtggt tagtttcgat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     2281 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     2341 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagttgat
     2401 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     2461 aaagaataca aagtcattta tgaagaagtc gcaaaagaag aaaagatcac accagaagct
     2521 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaatt ggtttccgct
     2581 cacaaagtaa atgcgtcttt tggtcagcag ctttctgtta acgattcaat agaagctatt
     2641 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagcttgtga acgcgtggat
     2701 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc tcagattctt
     2761 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     2821 cctgaagtaa aaaaggattg gaatgatcaa ttgaagcatg aaatctacca acaagagatc
     2881 agaaagcaaa aacgtgccat gttgtttcaa caaggtagac agcaagaaag ggagtgaaat
     2941 cgtcatgatg aaaaccgtta ttttagcaga aaaaccgtca caagcgaagg cttatgccga
     3001 tagcttttct aaagctaccc gaaaagatgg gtattttgag atccaagatc gattgttttc
     3061 aggagaaact gtgatcacgt atggttttgg tcatttagtc gagttagatt cgcccgatat
     3121 gtacgatgaa aattggaaac aatggtcatt agagcatttg cctattttcc ctacacatta
     3181 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     3241 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatagcttg
     3301 gacgatcatt caacaagcag gcgccgatca tggaaagata tttaaaagac tttggatcaa
     3361 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagatg cagaagagac
     3421 ctacccaaaa tttgaagaag cacaagcacg ccagatcgcc gattggttga tcggcatgaa
     3481 cggtagcccg ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gtttttcctt
     3541 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttacaggaaa agattagaaa
     3601 cttccaaaaa gaaccatatt ttgaaggaaa agcccaagta atcgctcaaa atggcgcatt
     3661 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     3721 aaaagaaaag ggggttcaat tgggaaaaca gccaggtacg atccaccaag ttgaaaccga
     3781 gaaaaaaagt gcggcaagtc cacgtctttt ttctctatcc agccttcaat ctaaaatgaa
     3841 tcagctcatg aaagctagtg ccaaagatac tttggaagcc atgcaagggt tgtatgaagg
     3901 gaaatatcta agctacccac gaacagatac cccttatatt acagaagggg agtatgcgta
     3961 tctgttggat cacttagacg aatacaaaca ctttttaaag gccgaagcca ttcctactcc
     4021 tattcataca ccgaatagtc gatatgtgaa taataagaaa gtccaggaac attacgcgat
     4081 cattcctaca aagacggtca tgacggcagc ggcttttgaa caattaagtc cactgcagca
     4141 ggctatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa agtataccta
     4201 tgaagaaaca acgatcttga cgcaagttca gcagcttcag ctaaagacag tcggaaaagt
     4261 accagtagat ctaggttgga aaaagctgtt tggcaaagag agcgacagaa aagaaaagga
     4321 agaagaaccg ctacttccta aagtgacaaa aggagaagcg gtgacggtag atctacaagt
     4381 ccttgaaaaa gaaacgaagc caccacaacc ttataccgaa ggtacgttga tcacagcgat
     4441 gaaaacagct ggaaaaaccg tggatagcga agaagcacaa tccatattga aagaagtaga
     4501 aggaatcggt acagaagcaa cacgagcaaa tattattgaa actttgaaac aaaaggaata
     4561 tatcaaggta gaaaaaaata agcttgtggt gacaaataaa gggattttac tttgccaagc
     4621 cgtggaaaaa gagccgctgc taacaagtgc cgaaatgacc gccaaatggg aaagttactt
     4681 attaaagatt ggtgagcaga aaggaacaca agctactttc ttagctaata tccaaaaatt
     4741 tgtctctcac ttgttggaag tcgtaccggg acaaatccag tcaacagatt ttggatcaac
     4801 gttacaagag gtgaaagcag ccagtgaaaa acaggaagca acgcgtcatt taggtgtttg
     4861 tccaaaatgt cgggaacaag aagtcttgct ttatcaaaat gtggcggcat gtacgtctga
     4921 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag ccacacaact
     4981 gaaagagatc attcaaaacg gccgaacaag ccaatcagtc agaggactaa aaggtcagaa
     5041 aggttcgttt gaagcaacga tcgttttaaa agaagacttt acaacaggct ttgaattttc
     5101 tgaaaagaaa aaaacgaact ataagaaaag aacacgccgc actacaaaat aatgaagggg
     5161 ttatcctatg cgaaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagcaaaaat
     5221 tcgtttagaa caagagaaat tacgtgcaaa taaaagaaga ctgcaacaat taaagaacca
     5281 gcagcgcatt caaaaagaaa tcgaattaga tcgatagacg ttaatcttgt tacaaataaa
     5341 ctactatgat atatttgatg tagtgtattt gtaacgaagg gaggggaagt aaatgcaaga
     5401 taaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccaggaa
     5461 atttggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     5521 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     5581 acgattttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     5641 gaatatgccg aaattcattc acttaacttt tccccatggc tataacgttg atcgttcaat
     5701 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     5761 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     5821 ttgtgatatt tggaatccga gatatgaatt tgaatatgaa atgaaattag aagcattaaa
     5881 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     5941 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6001 gacaccgaca caatttgcag caaaaacaag aaatttagca aagagtacag gattaaatgc
     6061 acagttagtg caacggcatt ttatgatgga tcgtctaatt gaacaaattt ctgaatcaaa
     6121 gtacaaaaat gacttcattt tgaaaggcgg ctttttatta ggatcaaaat atggaatcga
     6181 tagaaggaca acaattgata tcgatacgac atttagaaat agcaaattaa ctgaagaaaa
     6241 attgaagagc atttttaatg atttaactag aaaacccaca aaagaaggca ttgttttctc
     6301 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     6361 ggtggctaat ttagagaaag tacgtgtacc gtttaaaatg gacgtgacaa caggagattc
     6421 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaagtgga
     6481 gattccagct tatccaacag aacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     6541 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     6601 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     6661 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcagag gaaatgacta
     6721 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     6781 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     6841 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     6901 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     6961 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7021 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaacg
     7081 atggcgacat tagctaaaaa gggcagtttg atcggcgttg ttggacggat tcaaacccga
     7141 acctacgata accaacaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     7201 caactattag aaagtaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccagc
     7261 agtccaagcc ctaccacctt tgaacaacgg gatgtagcta cgcctaacaa caatggattg
     7321 aacgcttcac aaaatccatt tggcggacaa tcaatcgata ttagtgatga tgatttacca
     7381 ttctgattgt aaaagatcaa taaagttgtt ataatggata cgaaaagagg agttgcgcta
     7441 acaactcccc taacagcacc gtttaagacg gtgaccagct taatattatt tttgaaaaat
     7501 aatcgtcgac cggctaaagc tgacggttat tttttttgat tgttgtttac aactgctaag
     7561 attccaaaaa tgattgttgc gatcaaagaa ccgaaactaa tcattaatcc tagcgccgtt
     7621 tcaacaggca aaaggcttct cctttctgta agattttgga agtacgcaca tacgcaccac
     7681 ctcactttca atcggatagc caccgtcaca aactttactg tcttgatcat tatagcatat
     7741 ctaaaatcga ataaaaattc tcaattttag ctgtttttgc tataatttta gcgaggtgat
     7801 cgtgatgaac aaatatgttg gtttgcttga taaaatccga gtaataaaaa cacaaccatt
     7861 attggttcgc tttactttac aaacaattca tgaatcgatt aattgtgtag ttgcagatat
     7921 tgaaattatc gataaattgt taattatgga tgatggaaaa tacaatattg ccgtcacagg
     7981 tcatttcaat aaacggaatc aattagtcat tgaatcgatg caaattagaa accccgatca
     8041 ttttacgcga tcgatgggca tataaaagaa gagctgcagt cctaaatgag gattgcagct
     8101 ctttttgttt tacatagaaa caggaaaaga cctttttagg aagacacaag tgccttctca
     8161 attgaaaaac ctttctctca ctccaaccgc caccgccgtt cgagaagaaa ggaagtgaac
     8221 gttgcacgtt cactaagata tggtgtcttg caaagcaaga caaaatagaa aaaacttcct
     8281 ctcaccaaaa ggttcgttcc tgttcgctat ctctttattg atttgccaga ccggcaacaa
     8341 gttgcctttt atcaccaaaa agcgacaagg acaagggtaa atggcacgct gcgcgccctt
     8401 gtccttgtcg cttttcgttg attcattctg gccaacaaat caataaagaa agaactaacg
     8461 aaaggaaata aaacctttcc taagaggagg cagaatcaat catgcgaaag aaatttgatt
     8521 attggggtgt tcccttcagc gaattattcc caaactatca tgcaccacat actgtcgaat
     8581 gcgattgtgg agaaagagcg aaatgtatca aaagctatcg tttgtatcaa tgtccaacat
     8641 gcgggaaaaa atataccttg tcttatggcg attatgtttt gattgatgag aaagtaaaga
     8701 aacg
//
LOCUS       DAXLPY010000089         8581 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.090, whole genome shotgun sequence.
ACCESSION   DAXLPY010000089 DAXLPY010000000
VERSION     DAXLPY010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.090"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(226..625)
                     /locus_tag="ACF3UF_002399"
                     /pseudo
     CDS             complement(226..625)
                     /locus_tag="ACF3UF_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
     gene            complement(622..858)
                     /locus_tag="ACF3UF_002400"
     CDS             complement(622..858)
                     /locus_tag="ACF3UF_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3672470.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            complement(1018..1302)
                     /locus_tag="ACF3UF_002401"
     CDS             complement(1018..1302)
                     /locus_tag="ACF3UF_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672471.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            complement(1473..3701)
                     /gene="topB"
                     /locus_tag="ACF3UF_002402"
     CDS             complement(1473..3701)
                     /gene="topB"
                     /locus_tag="ACF3UF_002402"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFD3672472.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            complement(3875..4285)
                     /locus_tag="ACF3UF_002403"
     CDS             complement(3875..4285)
                     /locus_tag="ACF3UF_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3672473.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            complement(4402..5565)
                     /locus_tag="ACF3UF_002404"
     CDS             complement(4402..5565)
                     /locus_tag="ACF3UF_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD3672474.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            complement(5743..6597)
                     /gene="aroE"
                     /locus_tag="ACF3UF_002405"
     CDS             complement(5743..6597)
                     /gene="aroE"
                     /locus_tag="ACF3UF_002405"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFD3672475.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            complement(6876..7646)
                     /locus_tag="ACF3UF_002406"
     CDS             complement(6876..7646)
                     /locus_tag="ACF3UF_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3672476.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            complement(7649..8530)
                     /locus_tag="ACF3UF_002407"
     CDS             complement(7649..8530)
                     /locus_tag="ACF3UF_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3672477.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
BASE COUNT         2355 a         1809 c         1429 g         2988 t
ORIGIN      
        1 tatatattat gtaaactaaa atatataaaa aatcagccca ctagttctaa accactattt
       61 cctactattc actcttttgt attcctttta aatcaattat ttcaaaatta atccatattt
      121 tccatatttt tatgaaaaaa ctattttgta tgattaaaca taaaaaaatc agcatattcc
      181 ttaatgacat gctgatctaa ttgagaaata aagtttttaa ttcgttcatt ttattgcggt
      241 ttgtcgtaaa taactggtta tcttggactt tagtgaatcg aaatccaatg aactagtggt
      301 aatcattatg ataaaatcaa cagcttcttg acgagaaaaa gcaactggac aattattcaa
      361 ttgaagaaac aacaacatgg caacaagagc agttcgttta ttgccattat gaaaaggatg
      421 ttttttagct aaattaattg ctaaaatcgc cgctttttca tagatttcag gatagagttc
      481 ttgattgaat actgcttgtg aaggctgttt gacggccata tctaatgcat ttgcatcttt
      541 tacaccgatc atttcgcctg gcgagtgacg gtaaaataac tttcgcgttg attttgataa
      601 tttctttagt cgaaagatac ctcataaatc aaccaaatct tttaacgcgt cttcatattg
      661 attcatgatc gaatcaacta atgaatcaat atcaggttct tcttgtgctt tgatcattcg
      721 tacagaacca tcagattgaa aaacataact gattgcgtca cctgtctgca cacccatgaa
      781 ttcttttact tctggtggga tagttgttac atcgctattg ccagattttc taattttata
      841 ctttttcatt tttttcatat ttcgccaccc tctataccat tctcattcta tagtaagtac
      901 attatatcca agtatatact tttaatcaat gtatatactt ttattttgct ttttcttacg
      961 aaaaaatgac aaagaaaaaa gtttgtgaca tgacttttgt cacaaactct cgtattctta
     1021 accaaaatat tgatgaaata cttgtgtaat aactggtaga aaataaataa tgatcatagc
     1081 cgctaccacc accaacaatt gttttcgctg tttctttcgc tttagcatgc ttgtcgtttt
     1141 atgaaaaaaa taagtagcgc ttttagctcc tgcagtcaaa gtcgataaaa tcaacgttgg
     1201 tgaatatgct gtttgattgt gcgtcaatga caacaacttc gtcccgtaat caggatactt
     1261 tagaaatgct tggtacacag ccacaatcgt gattgctccc ataagataat ttaaaaatga
     1321 atgcactttt ttcaaataaa aaaactcctt gctatctata taaaatcagc ctaccccaac
     1381 gtttttgctt gattcactga tattttttag ttttattggt atttatattc tcacttttcg
     1441 gaataaatat tccgctattt cattgttttc atttactcta cttcgttttc attatttttt
     1501 cttgatgttt ctttgtttcc atcaactgct tttgttccac tgttttcgat ccatggaaaa
     1561 gaaaaaccga ttgtcatatc ttcttttaat actaaaactg catcgaattt ccctttttta
     1621 ccagtaaaac ctttgacaac tttacttgtc tttccttttg aaagcaaatc tctgagattc
     1681 gttttagtca gcttcttttt agctactgtt ggccacaatt tgaagtcgca ttccggattc
     1741 aagcatgtag cgattttagg ataaagcatg actattccct ttttacattt tggacatctt
     1801 cctaattgat cgtttttctt ctccatcgct tttatctgac gtgtcccgct aatctcatct
     1861 gaaaagtcta ccttgtcgat ttgattagga acttctgcca ataaatgtag gatgaatttt
     1921 ttgatattct ctaaaaaaac agatggtgtc ccctcttgtt taccaatttt tctcaagtac
     1981 ccttcccagc gcgcagtcat ttctgcgctc gtcagtaatg gttcattggc tactgcctta
     2041 caaagagtga ttccttttgg cgtaacagtt atttcgtttt tattgacttc gatgtaatgc
     2101 ttctgcttaa gattttcaat gatattggct cgtgtagctt ctgtccctat tccttctact
     2161 tctttgagaa tttcttgcgc ttcatcatta tccagcgttt ttcccgcagt tttcattgct
     2221 gtgatcaacg ttccttcggt atagggtttt ggaggttgtg tttctttctc catacttttc
     2281 agttctactt ctgcttcttc attttctacg ataggaggaa gagtctgagc ttctttcttt
     2341 tttgacttga tgcgtaagat ttcctgccaa ccttgctgta atgggatctt tccgatgctt
     2401 tttagcttta attgctgtac gcccgtcatt acggtcgtct cttcgtagat ataatctgca
     2461 gcaaacatag ccacagtagt gcgcaaaact tgcaaataga ttgcttgctg taatttggaa
     2521 agcttcgcaa agcgtgcagg agtcggaatc gtctttgtcg gaataattgc atgatgttct
     2581 tgaacttttt tcgcatcgac atatcgtttc tttgctttga tctcagttgt ctgtacttct
     2641 tctattccta aaaatttttt ataattttgc agatgtttaa ccagatactg atgctcattt
     2701 tctgtaatgt aaaaggaatc cgttcttgga tagcttagaa acttgctttc gtacaatcct
     2761 tgagcagcat caagtgtagc tttggcactt gctttcatta gctgattcat ctttgtctgc
     2821 aaactagata gcgaaaataa acgtggacta tgcaacctct tttccttttt cgtaacttca
     2881 agaatccgtc cgttttgctt acctaaatgc gctccaagtt tttctatttc cttcgttaac
     2941 tcttcttggg ttttaaatgc tttttttggt acgatttttc cagaaaactg ccctttgttt
     3001 gtcgtaatta aaccttctcc ttcaaagtac gtttcttttt tgaagtgttt gatttcttct
     3061 tgcagctgat aaatcatata gagtgtcggt gtttgtacac gaccaagaga aaaactgcca
     3121 tcaatccctt ttcgttgaag tagcaagcta tataatggac ttccattcat tccaatcagc
     3181 caatcagcgt tctgccttgc ttgcgcttct ttatattttg gaaaatagtt ctttccaggt
     3241 tggagattct taaaaccttc atagattgct tctttttcaa gagaattgat ccataaacgt
     3301 aaatagttct tttccttaga aaatgcgttt gcttgtcgaa taatcgacca cgcgatggct
     3361 tcaccttctc gatcaccatc tgttgcaata atgatggtat cggctgactg caattctcgt
     3421 tttacgatcg aaaattgtgc acgtttgtcc attggaactt cgtaacggaa ggtttctggg
     3481 aaaataggca aattttctaa agaccatttt gcccaacgct cttcataagc tcctggagca
     3541 accatatcta ccaaatgtcc aaaaccataa gtgatggtta cttcaccagc aaacaatgga
     3601 tcgctgattt cataataccc ttcatgccgc ttttgctgtt ggaaggtttc ggcataggct
     3661 tttgcttgtg aaggtttttc agctagtatc accgtcttca tcttctgacc tccgttactt
     3721 aattttttgc ggacttctct attatggaac atattttcgc atctggcaat aaaaaaaaga
     3781 taccgtatag tcgaaataga cacaaaaaca tcaagcaaac aaacgatgat ccgtttgctg
     3841 cttgatgttt ccagaaaata ttcatcttta gctgtcactc ttggttaatc tgccagttga
     3901 tgccaaatcg atcagttacc atcccataca actgagccca cggaacagca tccagtggca
     3961 tctcaatctt accaccctca gctaagcttt caaataggcg cttcgtttct tcttcatttc
     4021 ttgtctggat gactaaagaa acattatttc ccacaactaa ttcaggacca attccttctg
     4081 gcgtatctgc aaacataact aatgtatcat aaatgttcag ccgtgcattc gtgattagat
     4141 tttttgcttc ttctggcaag ttcatttgtt ctattccagg catttcaccg tatgtggtga
     4201 tacctgatgc ttcagtctga aaaacttttt cataaaaagc gatggcttca cgcgactcat
     4261 ttttgaagtt cagatagata tccaatgtaa acagctcctc tcttggttaa atctaccata
     4321 agaaagcgtt ttttacgagt gaatcgtttg attgattcat gacaaaagcc ttgcgcagct
     4381 tcttcttgat cttttttatg atcatttatt caaaaaatct gtaatagcag attgattcat
     4441 ttgattatca atttcaagaa tactgccagc ataatcactt tgcccataat tccacgaacc
     4501 gtctactggc acacttattc gatcaatgcc accagctcct cgtgcaatcg aaaagaggtt
     4561 tttcgtcaag aaccaagcag tgacatctgt ggatgtatat cctaaagctt taccagctgc
     4621 ataaggtgca cggatcagat tcaatggatt cttcaattgg ctgaaaatag cgttcattac
     4681 ttgctgttgg cgtctgacac ggccaaagtc tccttgttca tccattcgga aacgtgcgta
     4741 ctgcaaaaga acatgtccat ccatcttctg gccccctttt ttaatatcta caccatccag
     4801 attcagatct ttttctgcat cgatcttcac tccgttcatg aataaggcat cgatcacttt
     4861 ttcaaacgat ttgaaatcga ctttcgcata gtattgacaa tcgattccaa aattttctac
     4921 taaagtttga cgcactagat cggctcctcc gtatgcataa gctgaattga tcttattttg
     4981 tcctacccct gggatcgtaa cgaagctgtc acgcataaaa gaaatcagtt tcggcttatg
     5041 ggaaggacca tccaactgta agaccatgat cgtatcggct cgcccggcat cttctccgcg
     5101 tgtatcactt ccaaggatca aaatattatg cgcaccattc gtcgcttttt gcccatgaaa
     5161 ggtttctgaa gtcgctgcct ctaagcttgt gtcatgttca gctacatatt taccaataaa
     5221 aaatgagata cctgaataaa ggatcaaaac aagcaaaatc gatagaatga tttttttcca
     5281 cgatcgcttt cttcgaggtt ttaacggttt gttcttcttt tgccgattga aaaatttttt
     5341 atttttttgt tgttcttctg ctcttggtgc atctctgtat atctgttgct cgtattggtt
     5401 caaatgttca aatgaatgct gctctctttc ataaatacgg gtagcatctt cctcattttc
     5461 catacgcgtt cgttttcgtt ctcttctagc aaaaatactc cccgtatccc gcttcagagg
     5521 tttcgccttc ttatggatgt ccttatagcg atccatccga ctcattgtgg ttcctcctcg
     5581 tttcttactg ataaataaag gatacgataa ccaatcgaca aaagcctatc attttttgat
     5641 aatttaataa aaaataacga aataaatgct tcgatacata aaggattact tttcttgaga
     5701 ccgtttatgc gagaataaaa gatctttatc tattatcctt ttttaatcaa acagcttttc
     5761 aatcacatgg atcggcatct tttcctttgt ccataattca aacgcgattg ctccttggta
     5821 gatcaacatg ccaagtccat tgtatccttt tgctcctact ttttttgctt cttttaataa
     5881 acgtgtttct ctaggtgcat aaatcaaatc aaaaaccgct agattctcat gcatcatgct
     5941 tatatctaag agcggtgact gattgatttt ctttcccatc ccgatatctg ttgcattgac
     6001 tagaagacag ctttctttca agtcttttct taattgatgc gtatcggcaa agtcacgaac
     6061 ttttatctta caagaagttc gatagctgag ttgttcgaat gtttctttta cttgagcgaa
     6121 tgtttggttg tttcgtttat aaactacgat ttcctcagcg ccgtctaacg ctgcttgaac
     6181 agtgactgcc tttgctgcac ctccagctcc cagtagagtc atttttttct ttttgatcga
     6241 aatcccagct tcttgcacgg attgcatgaa gcccgcacca tcagtattat agccaatcaa
     6301 acgacccttt tcgtgcacga tcgtattcac tgctccgatc aattgcgctt cctggcttac
     6361 ctcatccaga taaggaataa ccgctgtttt attcggcatc gaaagattta cacctaacat
     6421 atcaaaagtt cgaatacttt cgactgcttg cttcaaattc attggattta cttggaaagc
     6481 taaatacacc gcatcgatgt tgtttgcttc aaaagcagta ttgtgcatca atggggataa
     6541 actgtgagaa gccggatcag caaagagccc agctaatttg gtttgtccag aaatcatctt
     6601 attcctcctt tgttcttact tcaataaaaa aagccactta gcgtttgata cgaaaaagta
     6661 cgaaacgtct aggtggcaaa gtagcaaatt cttttctcat cgtttacttg tcagagcaaa
     6721 gaatattcta tttaattgtt aaaatcattg actacgtgat cctacaaaac acccaaatat
     6781 gtttaattgt ttattgtttt aagtatagga tgaatcaaag gaagatgtca atgagttttc
     6841 aagtccttct actgaaagga atttttctgt cgaaatcaat ccactacttc ttcaaagaac
     6901 tgcaaaaggt cgcccattgt caaatgttgc ttttcttttt cagaaatatc ttgaacgatt
     6961 ttcccttttt ggagtacgat cagacgattt ccgtatttca aggcgtcttc cattcgatgc
     7021 gtgatcatga gacaagtcaa tttttgttca ttgatccgct gatttgttaa tcgcattaat
     7081 gctttagctg ttttaggatc taaagctgca gtatgttcat ctaataatag taactcagga
     7141 gctgtgatcg tcgccatcag caagcttaat gcttggcgtt gaccaccaga taattcaccc
     7201 gctggagtat ccaagtgttg ctctaggcca ttaccgactt cttgacatag tctgaaaaaa
     7261 tcttcttttt gatttttcaa gttacgtaaa cggaatttcc gtttttgacc tcttttttgt
     7321 gcaagtagca aattttctgc tactgtcatc cgaggagccg ttcccatctt ggggtcttgg
     7381 aaaactcgag aaaggaatcg tgctcttttt tcttctgaat cttttgtgat cagctgatct
     7441 ttaaaagaga tcgatccttg actgagttga agcgtaccag cgatcgtatt gaacagtgtg
     7501 ctttttccag caccattccc gccaaggaca gtgatgaagt ccccttctct gattgtaagg
     7561 ttaatttcat ccaatagtac tttctcttca ttcattccat tgtttacgac ttttctgcca
     7621 tttttgattg tcaatatatc agtcattact atgcctcctt ctcaaaaccc gtttttaagt
     7681 tcagtgcttt cttcaattgc gggatcatca gacaaatagc taagatgata gcggagaaca
     7741 acttcagata agtcgtgtca aaccctagtt tgattactac taaaatcaat agctgataaa
     7801 tgatactgcc gacaacaata gcaatcaatc tttctgctag cgtcaattct tggaagatca
     7861 cttcaccgat gatgatggaa gcaagaccga tgacgattac gccaatccct ttatttacat
     7921 ctgcatatcc gtcgttctgg gcaatcagcg caccggataa tgcaatgaca ccgttcgaca
     7981 aagttaaacc taaaattttc atacgatcgg tttttatccc taacgaccga gccatcgttt
     8041 cgttgtctcc tgtcgcaata tagccttgac ccaaatctgt attgaagaag aatagcagta
     8101 cagcaatcaa gatgcccaaa gagatgaagc caagaaggac tgtgtcaaag taatcaggta
     8161 acccaaagcg atggaagctg tcttgtagaa tcggatgatt caataaagaa agatttggtg
     8221 ttcgcatcac aaacaaaata actgagttca atcctgacat cactaaaatc cctgctaaaa
     8281 taaccggtat ctttcctttt gtataaagta accccgtaac gagtcctgct atcatgccag
     8341 cacctacgcc taataatgta gctacaatcg gcgctacccc atgagtaata gctgtcacac
     8401 agacagcagc acctaatggg aaggaccctt ctgtcgtcat atcaggaaag tctaagatcc
     8461 gataagtcat gaaaatccct aatcctaata ttgcccaaag catgccttgt gaaatagctg
     8521 atacgatcat ttgtcatcct ccttagatgt ttcttgctgc gagtcatctg taatgatttt
     8581 g
//
LOCUS       DAXLPY010000090         8505 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.091, whole genome shotgun sequence.
ACCESSION   DAXLPY010000090 DAXLPY010000000
VERSION     DAXLPY010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.091"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(445..975)
                     /locus_tag="ACF3UF_002408"
     CDS             complement(445..975)
                     /locus_tag="ACF3UF_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFD3672478.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            1080..1631
                     /locus_tag="ACF3UF_002409"
     CDS             1080..1631
                     /locus_tag="ACF3UF_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3672479.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(1784..2257)
                     /locus_tag="ACF3UF_002410"
     CDS             complement(1784..2257)
                     /locus_tag="ACF3UF_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3672480.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            2395..3867
                     /locus_tag="ACF3UF_002411"
     CDS             2395..3867
                     /locus_tag="ACF3UF_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFD3672481.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLTKAGDNA"
     gene            3864..4574
                     /locus_tag="ACF3UF_002412"
     CDS             3864..4574
                     /locus_tag="ACF3UF_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFD3672482.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            4926..5210
                     /locus_tag="ACF3UF_002413"
     CDS             4926..5210
                     /locus_tag="ACF3UF_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFD3672483.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(5491..5910)
                     /locus_tag="ACF3UF_002414"
     CDS             complement(5491..5910)
                     /locus_tag="ACF3UF_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFD3672484.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGWFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(5912..6496)
                     /locus_tag="ACF3UF_002415"
     CDS             complement(5912..6496)
                     /locus_tag="ACF3UF_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFD3672485.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLNEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFGIVNEHSKRWQGD"
     gene            complement(6543..8018)
                     /locus_tag="ACF3UF_002416"
     CDS             complement(6543..8018)
                     /locus_tag="ACF3UF_002416"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFD3672486.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDVIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGMSAKTIFDGTVPFDMKEHFVRAKFQEVKDWEKYLK"
     gene            8199..>8505
                     /locus_tag="ACF3UF_002417"
     CDS             8199..>8505
                     /locus_tag="ACF3UF_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672487.1"
                     /translation="MKKMEESFPKAAKVENIANILKVTFENGEVKYVKSHWTEEITDD
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     "
BASE COUNT         2587 a         1563 c         1678 g         2677 t
ORIGIN      
        1 ctgggagcat tatttcattt tgaagtcact aatttaactg tgtgaatatg cagttgttac
       61 aatctttgat aaacggtgtt caaaagcttg catctacggt aataagccca accaaacaaa
      121 aaatatgagg agctattttt atttggctgt tcttattact tgatgcagaa cagctttttc
      181 acaacctctg attcacggtg ttccaaaagt agcttcttcg gaaataagcc gaaattttac
      241 aaaaatttga gaagcaattt ccgtaaattc cttcttattt cttgaagctg accacttctg
      301 tcacaacctc tttcttaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac
      361 ggcaaaacat gaggaactat ttttccgttt ctttctctaa tactcaggtc agaacgctga
      421 tttcacaacc tctctttcac aaccttattt tactcgttta taattttcat cgaaatattt
      481 tccgctacgg atatcatctg gcattccatc gtatggttct tcgctaataa catcttcatt
      541 gtctatacct gcatcaccca tataagtgat agtagcaaat tcaggaacaa gtaattttgg
      601 ataagtttca tatttttcac gagctgcttc catttctgcg atatgttcgt tttggaaagt
      661 aacagtgatt tctggatgtt cttcaaccca tttagggaaa aagatcattc cgtgaagttt
      721 cttttcattt ggcataaagt ccaatgccac gtctgtccct gttggctctg tccaagtgat
      781 tttgaatacg ccgtccgtca atttaacgat atcagcttct tggtctttta cccaacggcc
      841 tttgaccatt ccgccatgga tacggtaatc aacagtatgg tcatttttgg cataccattc
      901 atattcccaa ccattatcat acgtatagat aaagtgagtt ccaataaaat cttccaattc
      961 tttaaattct ttcatgttta agcatctcct tataaattaa aacatgtaat aaactacatg
     1021 ttttcgatta ctcatttatg atagaatgga tttaaagatt tgtcaaggag ggaaaactga
     1081 tggcaagaaa aaatacactt cgatatattt tgttagggtt attaagtaag aagaagatga
     1141 caggatatga attgaatcaa tcgttcaaaa atgaaatagg agaattttgg caagcaaaac
     1201 atagtcagat ttatcctgaa cttgcaaaaa tggaagagca aggaatcatt cagcatcaag
     1261 tagagatcac aggtgaaaaa ttggaaaaga aagtttatga attaacagaa gaagggaagg
     1321 aacaattggc agagtggatt catacaccca ccaatgaact accggttaat cgagacgaat
     1381 ttgttctgaa attgtatttc gtcaaagacg tgaatgatcc ggcattagta gaaattattc
     1441 agcagcagcg tgaccttcat gaagaaaaac gacttcatct attagagcga aaaaaaacga
     1501 tctttcctac tgaaaaagaa aaacatgaaa attacggaca ctacctgatt ttagcgcatg
     1561 cgatcaatcg ggaaacagaa tatgcaaatt ggctaacaga tgtattagaa gaaagtaacc
     1621 gaaaaaaata aaaaaatatc cgaacagtga tggagaattc ctttctatat gaaagaaacg
     1681 cagatcaccg ttcggatatt cttatgttca aacaggcctt ttttcaagta tttatgtagc
     1741 atctacttat taaaaagctt ggtacttagg agattagtgg cgtttagagt tcttttaaca
     1801 gctgttcgta gtcagctttt tcatcgacag gaaggagctt gtaagttaat tcgtctgtct
     1861 cgttgtcatg aatgatgtac atcttagcat tctcttcttt gaagttaccg atttgtaaaa
     1921 tcgtatagcg ttcgtcgatc aattcgatat ctttgattgc ttttgaaaaa actttacgga
     1981 catggtgcat tttcttttgg cggatttctg ccttttctgc agcttttgac aaagtaaatc
     2041 cgtcatctaa atattttttg atcagttcta cttttatgac tgtaggtaaa cgatattttc
     2101 taggacaatt cgcatcagct tcgatcgaac gaatgaatcc cttttgttcc caatacctta
     2161 attgacgtgg agacacacct acgatatcac ttaattcact gatgccaaca accaattgat
     2221 cattttccaa caaacgttta agggaagccc caaccatttt tgtcactcct tttgtcctct
     2281 tgcttccctt aattatatcc gtattaactt atgtgtcaag taggttgaca aatagcgaat
     2341 ttaggactaa agtattctag tagtttcaga aaaaattcag aaagaaggag aaatatgagt
     2401 aacaaccaac ccgtagatat ttacggaaaa ccatataatc ggacactttt agttgttgtc
     2461 ttattaattg gtacattttg taccgttttg aatcagacct tattgacgac agcttttcct
     2521 acattgatga aagctttcga tatttcagcg tctgatgtgc aatggttaac gactggtttc
     2581 ttgctagtca acgggattat gatcccaata acagcatggc tgatcaataa attcagttca
     2641 agaaatttat atctttctgc catgacgatc tttttgatcg gaacgattac ttgctttaca
     2701 gcacctaatt ttagtacatt actaatcggt cgcttgatcc aagcttgcgg tgtgggagta
     2761 tcgatgccat tattgcaaaa tatcatgcta tctattttcc cgccagaaaa aagaggatca
     2821 gcaatgggga tgtcagggat cgttattgga cttgctcctg ctttaggccc tacattatct
     2881 ggttatatca ttgataacta ccattggcgt gacttgtttg gtatggtact gccaatcgtt
     2941 gttcttgtct tggttttagc attcttccta atgaagagcg ttattccatt gtcaaatcct
     3001 agcattgata ttttatccgc tattttatca acgattggat tcggtagttt gctttacgga
     3061 ttttctagtg taggagatga cggctgggga agcttgaaag taattggttt cttagttgtt
     3121 ggtgtgattt tcatcgcatt gttttcatgg cgtcaattac atttggaaca tccattcttg
     3181 gaacttcgcg tattcaaatc atctacattc acgattgccg ctgttttagc tggtgtaaca
     3241 aatatggcga tggtaggggc agaaatggtc gtaccattgt atattcaaaa tattcgtgga
     3301 gaatcagcat tccattctgg cttgatgttg ttgccgggtg cattgatcat gggggctatg
     3361 atgcctgtta cgggtgcgat tttcgataaa tatggcgcga aacgtttagc catcacaggg
     3421 atgttcattt tgacagccgc aactgcacca tttgctttct tgacaaaaac gactccagtt
     3481 ttatatatcg tgatccttta tgcgatccgt atgtttggga tctccatggt catgatgccg
     3541 gtaacgactt ctggtatgaa tgcattgcca aataacttga tcagtcacgg gacagcggta
     3601 aataatacat tccgtcaaat cgcaagctcg attggtacag ctattttgat cagtgtgttg
     3661 acgaatgtga caaaagcaaa tatcccaagc aaatctgtat tggataatac accattagct
     3721 tataaagatc aggcaatcaa tgccacactg tcaggttacc atgccgcgtt tatcgtagcg
     3781 atcatctttg ggatccttgg ctttattatt gcctttttat tgaagaaaaa agaacctgtt
     3841 ctaacgaaag cgggggataa tgcatgatta ttggagtttt gattgtcagc ttgcttgctt
     3901 ttgctttaac gaacgtgttc gctaaaaaaa catggcaaac ctttttatct ttgattttcg
     3961 gactaatctt cgtcgcttca ctaagtttga tcgtcgctaa tttgtccaat cactttggaa
     4021 tggaaaaagt aacggaaaca aaaacagaaa aaattgtttc cagtgctgat tcccaaggag
     4081 cagatatgct tttgtataaa gctttaggga atggaaaaga aaaagtgtat ctttaccgaa
     4141 caaatgaaaa acaagaaaaa ccaaaagcaa ctggtacgga taacgaaaca aataaagtag
     4201 aaaagacaga cggcgatgct gaaaaagtga cgaaaactac ttattgggaa tacaaaaacg
     4261 acatgtataa attctggttc aatattgctg ataacaatca cgaatatgac agccgagtga
     4321 atacattcaa aatcccagag acatgggtag aattaagtac ggaccaagca gccaagttag
     4381 ctgaattagt taagaaacag caaagtacga tggaaagtga agcaaaagct tatgttcaag
     4441 acggtatggt aaaagcaatg actgaaaatc caaaaatgag caaagcagag caagaacaac
     4501 gtacgaaagc cttagctgct gaattccaac aacaagcatt cgcaaaatta gtgaaagaag
     4561 caaaaggcga ataatatttt gaacaccgtg taggaggttg tgaaaaagct gctctgcatc
     4621 aagcagtaag aacaatcaga taaaaatagc actccatatt tttcatctga ttggggttag
     4681 tgccgtagat gcaagctttt gaacaccgtt taaggaagag gttgtgagcc tgccgtttaa
     4741 ctctgagtca caaggagcaa tttcaaaaaa cagcttctca tgtttgttga atattgtgac
     4801 ttgtgaccga ggagttggca ggagaacacc gtttattcga aaaaaggaac tgcgacaaga
     4861 cttttgtcac agttccttct tttttttgct atgctatact agatgtaaaa aataggagaa
     4921 ataaaatgag ggaaatttat tcttttgaat caaaaatcta tgcttccgaa gtcggcaagg
     4981 gcggggcata tattattttt ccgtatgata taagaaaaga attcggtgct ggaagagtta
     5041 aagtccaagc aacttttgac aatgtgccgt acgaaggcag tatcgtgaat atgggtgtga
     5101 aaaatccaga tggttcagtc tgctacatcc ttggactacg aaaagatatt cgtaaaaaca
     5161 tcggtaaaga aatcggtgat attgtagcag ttacagtgaa gcaaaaataa aagaggttgt
     5221 gacaaaagac gtgtcacaac ctcttgataa acggtgttca aaagccagtt tctcggtagt
     5281 aagtcaaatt tatgcaaaaa tgtggaaacc catgtttaca aaatttttct tactactcga
     5341 aacgaagcgg ctttatcaca acctcttgat aaacggcgtt caatcagctg tccctcggta
     5401 ttagctcaaa aacggcaaaa tatgagaagc tatttttcca tttttttctc tcatactcag
     5461 gtcataacgc tgatttcaca acctcttctt tcataatggt ttttcaccat ctttataata
     5521 aactggttct ttgatatgga aatctatttt ttccaaccaa tctaaaatct tgtaacctaa
     5581 ctcttctgac atcggaaaag aggcgttgat ttgtgcattg gagatatggt caacatggat
     5641 accggaagta atcgtacaac ttcccggaac ggcagttttg atgatcacag ctattttttc
     5701 ggctaagaca tcgtctttat ggaaccaacc atcgtggcta gggaaacgta cagtttgcat
     5761 ctctgtatca cgagaaaatg tagtgactgt tccgatatgt ggtgtatctc cgcctgttaa
     5821 agtgatcaat aagtctttac cgattacttt aacagcagct tggatcgtga aacctagttt
     5881 ggttacttca actatcgttt ctttttccat attaatcacc ctgccaacgt tttgaatgct
     5941 catttacaat tccaaattga tccaaaagtt tcattgtatg gtgattaaca agatcttgga
     6001 tcgtttgagg ctgattataa aaagcaggaa ttggtggtat gatttgcaca cctagtcgtg
     6061 ctaatttagt caagttttcc aagtgaatgg catttaatgg cgtttcacga ggaacaatga
     6121 ctaactttcg ttgctccttc attgttacat cagcagcacg tgcaataaga ttgtcgccta
     6181 aaccaacaga gatacctgcg actgttttca tacttgctgg tacgatgatc attccatcgg
     6241 tcaaaaatga tccgctggcg acagcagcac ctaaatcttt gtttgaataa tggtaatcaa
     6301 acaggctttc gaattcattt agtgataagt cggattccag ctttaagttc tgttttgccc
     6361 atggactgat gattccgtgt gtttctatca tcggatattc ttttagtttc ttcactaggt
     6421 tgatggcata aatggtgcct gaagcgccac ttacaccaat cacgattttt ttcttccgtt
     6481 gtgccaattg ttccattttc cgcactcctt tttatgatgt caaaacagtt gcagatcatt
     6541 cattatttca aatatttttc ccaatctttt acttcttgga attttgcacg tacaaaatgt
     6601 tctttcatat cgaaaggaac tgtaccgtca aagatagttt ttgcactcat cccacggaaa
     6661 cgaatagagc caggattata ttctggtaat tctgatgggt ccaatggatg gtttctcatt
     6721 cctgggatca caatgacgtc tttatctcct tggaaacgag tgttgaaagt ccaaactaca
     6781 tcgttcatgt cgaaaatatc aacatcttca tcgactaaaa tgactgtctt caattctttg
     6841 aaggctgata aagcaagaat agctgcttga cgctgaatac cttcatccgc ttcgttttct
     6901 ttacggattt gcatgatggt catcaattta ccaccacctg caggaggatt gtagacattt
     6961 actacttttc ctggaatagc tttatcgacc aaggcaagaa tacttgcttc tgtaggaata
     7021 ccggccatag atacgtgttc ttcactggga ccaatcgttg tttgcatgat tggattgtct
     7081 tttcggtgag taactgcttt gactttcact acttgtacag ctggattagc atccccagta
     7141 tagccaggaa attctggcat tgcttttcct gagttcgtgt tgatatcttc ttgcattgtt
     7201 tcatttggca tgatttctgc ttcaatgatg aattcagcac gagcaatacc cacttcatcg
     7261 actgctatac catcaacgat ttgaataggt tcgttacgca aagctcctgc acaccatagt
     7321 tcattgtagc caagtggagt ggtaggtggt tcgaaagtcg tgccaatggc aattgctgga
     7381 tctaaaccaa tattgatagt gataggcatt ggtttattca aggcttcgaa ttgtttttgg
     7441 aagtgaccaa tgtggcgtcc gccaggcatg atgtacatac cgatcgtatc tttatcttct
     7501 agaaccatac gatggatcgt tacatcgctc attgtttttt ctggatctga tcctaagact
     7561 acacccattg tgatgtatgg accagcatct tcaggagtat ttgtaggtgc aggcaaaatg
     7621 ttgcgaatat cgaagtctgc atcggtagct agatgaacga cttcttgtgc tggagcgtct
     7681 gctttgtcta ctttcacagg tttgattgga ttttctacag cgtctttcaa gaaacgacca
     7741 agtgttcgat aatcatggtg caaaatttca cctacacgtt tacgactagc cattgttccg
     7801 atgttcacac gtgtgccggg gaaacctttg atattgttga aagtcatagc tggtccttct
     7861 tgagtcggac gttttactgt accgccagca ccgatataac ggtaaacacc agataattct
     7921 gcttcaggat cgatttcaat atctgtttcg tgatattgac ctggaagtgt ttttagttct
     7981 tcgatgactt ttcttaaatc atacggttga tctgtcatga gagattcctc cttagttgtc
     8041 tttacctatc tatagtaaaa ggtgaaaaag aggaaaacaa ttcaacttgt tcggtaaagt
     8101 attctacaat ggaatggatg cgtttttttg ataatagaat aaactatgat atacttatca
     8161 ataaaagaaa gcgcatactt agtgttggag gaaggaaagt gaaaaaaatg gaggagtcat
     8221 ttcctaaagc agcaaaagtg gaaaatatag cgaatatttt gaaagttaca tttgaaaacg
     8281 gagaagtaaa atacgtgaaa tctcattgga cagaagagat aaccgatgac ttgcaatttg
     8341 gaaaaaaagg aagaggaaaa agaaaaaatc ttctcgcact ttctcgtaat atgtggattg
     8401 ggactgaagt aacgattgaa gcagatggaa cagtattcat aaatggaaaa gacaggtata
     8461 cgccagaaga gttgtggtac aaaggaaaga aaagtatacc agaat
//
LOCUS       DAXLPY010000091         8329 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.092, whole genome shotgun sequence.
ACCESSION   DAXLPY010000091 DAXLPY010000000
VERSION     DAXLPY010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.092"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..2196
                     /locus_tag="ACF3UF_002418"
     CDS             <1..2196
                     /locus_tag="ACF3UF_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFD3672488.1"
                     /translation="VANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPG
                     GFDGVYTPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRK
                     MQQWLNVNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTY
                     PVSEGNSGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIAD
                     VVVIKGLLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDER
                     NKYLTTEELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTT
                     VIYFAVDLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFA
                     FVSDMSTGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSND
                     TNNDNYIAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPV
                     TEHDRKIYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVS
                     DFAGWLGDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAK
                     RNSDSTALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVG
                     IISFFIDKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            2276..2671
                     /locus_tag="ACF3UF_002419"
     CDS             2276..2671
                     /locus_tag="ACF3UF_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672489.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            2996..3613
                     /locus_tag="ACF3UF_002420"
     CDS             2996..3613
                     /locus_tag="ACF3UF_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672490.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            3654..3953
                     /locus_tag="ACF3UF_002421"
     CDS             3654..3953
                     /locus_tag="ACF3UF_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFD3672491.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            3987..4154
                     /locus_tag="ACF3UF_002422"
     CDS             3987..4154
                     /locus_tag="ACF3UF_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3672492.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(4199..4804)
                     /locus_tag="ACF3UF_002423"
     CDS             complement(4199..4804)
                     /locus_tag="ACF3UF_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672493.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            4929..7916
                     /locus_tag="ACF3UF_002424"
     CDS             4929..7916
                     /locus_tag="ACF3UF_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFD3672494.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            8065..8274
                     /locus_tag="ACF3UF_002425"
                     /pseudo
     CDS             8065..8274
                     /locus_tag="ACF3UF_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346508.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
BASE COUNT         2827 a         1284 c         1570 g         2648 t
ORIGIN      
        1 gtagctaatt ttggacctac cactgaaaaa atgtacgata atcaggttac tcctaaatgg
       61 ggcaaaaatc tacctaaaaa tattgtattt cttattcaag gtgccttttg gtgtaagggg
      121 attaatccag gtggcttcga tggggtatat actccatatt tagatactgc tgtaaaagag
      181 ttgcagactg atgcagggtt taatggaagc gctgtaactg gagttttgga tgcgaaatgg
      241 gccaaagcgt tatttgatat gagtgctttt gttcttgttc ccggcggaga tagtaaaatt
      301 agaaaaatgc agcaatggtt aaatgtaaat tatttagaat acacgggaat aatgccttgt
      361 gatggtattt atcaaagaaa ttcaaatcaa gcattaattt ttgcattaca agctgaacta
      421 ggatattctc ccagtgaagc aacagggtct tatggtaatg ggacaactag taaaacttat
      481 cctgtgtctg aaggtaactc gggaaactat gtaagaataa ttcaatatgg attatatgtt
      541 aatggttatt ttgaagacgg tacattcgat ggtattttca ctaaatatat gggtttagaa
      601 gtactggcat tccgaaaatt tatggtattg cctgaatata ctgaaatagc agatgttgtt
      661 gtaataaaag gactattgtc tagcgctgga gatattagaa gatctgcaga tggcgcagat
      721 acttctacgc aattaactag atctcaaatc caaacattgg ttgataatga tataaaaata
      781 gttggtagat atcttactgg tactgttgga attggaaaag atgaacgaaa taagtatcta
      841 actacagagg aattgaataa tattttttct aaaaatttat ctgtgtttcc tatctatcaa
      901 gatggaggtg cagcattagc ttattttact tatgatcgtg gcttatcaga tggtaagaag
      961 gctatagatg cagcaaaaaa tctaaatata ccattaacaa cagttattta ttttgctgtt
     1021 gatctagaca tgttagggga agaaattctt gcatatgctg gagaatattt taagggggta
     1081 tctgctgtaa tgtcatatag cgggtatcaa acgggtgttt acggaacaag aaatgtttgt
     1141 tctcaaataa tcaataacgg gtatgcttcg tttgcatttg tttcagatat gtcgactggt
     1201 tatagtggga atttaggttt tcctatgcct agacaatggt cttttgatca atttgttgaa
     1261 tttaccatag gaagtggcaa cggagctgtt ggtatcgatt taatcgctac atcgggtaga
     1321 gatagcggat ttaatgagtt atcaaatgat actaataatg ataattacat tgccaaatac
     1381 aatcagaagg ttataaatca gatggtacgt gcgtatcaat atctatcaca agctggtctt
     1441 gataatcctt ggaaccctca tttgacattt tatagatatg taaattattc tggtttgtca
     1501 tgggacatca tttcttctcc tgtaacagag catgatagaa aaatttatga tgaatatagg
     1561 aataaattaa ctaatagcga gggcctgtat aattatttta tagatcctaa tactggttca
     1621 ataataggtt tgcctcactt aattgtgacg ttacaatcac agatgtttct agccgacaca
     1681 atcaatgata gtgtttctga ctttgcaggt tggttaggag atttaatgac ttgctggggt
     1741 gaagttaaga aattaggaat acaaatggag caaggtgtat ttgcattagt aggtacggct
     1801 gcaggtggaa catttagtct agaagattta taccaagatg ttgacgcggt aaatgtttat
     1861 accttagcaa aaagaaattc tgattcaaca gctttatcgg ctttaaaaac gtactattgt
     1921 gataagggtg ctattgatag atttaatcaa tttgttaaga acagatttgg ttcttcagat
     1981 aaaatcgctt cagtaacaaa tagtttatta gaaaatgacg aaacagttga tatcttaggt
     2041 gtagggataa tttcattttt cattgataaa atagttaata attcacttgg gacagatttt
     2101 acttatcttg attttattgg agatgagggg aaagttgcaa atggattttc tgaaaaaatt
     2161 attcaatttc aagaaaatag aagtaaactt aattaagaat cgtttactat ttaaacagtg
     2221 tccttttcct ttttaaatat atacgataaa ataagtatat gaattgtaaa aggacatgat
     2281 gattatggaa gaaatagaat ggaataatct gactcaaaat aataaaaata attctggatg
     2341 tggaattatc tttatgtttg ttatagtttt gggaatagta gtacttttaa taactgtcaa
     2401 gatagtagat tactttgcga atactcctga agaacaaata cagagaaaac ttcctgagtt
     2461 tgaaagagta ccaccttatg atccaagaga taattcattt caagtaaaaa aattaaaaga
     2521 gtctccaaat gaaatgtggt ttgaagttac agttgaatca agcgacttca aagaaaaaaa
     2581 gaaagaatac aattatattg taaaggcaaa agtatcaaaa agatttattt ttaaccctaa
     2641 attagaaata tatagtgttg taatagaata atagtgttaa aaaaattgta aaagttaaag
     2701 aagtcaaatt ctgatgtgaa aaataaaata taccatggaa gacataaaag aaaaactgga
     2761 taactagttt atttaatggc agaccgttaa ggcctgccat ttttatgtat tttagcggaa
     2821 taaatataat catgcgggag tgtaaactta ctgtttcaaa aagtatactt tttgacatgc
     2881 cttgattttc tttgtttatg tatggcataa taaccacata atacaatttg aaacgtttct
     2941 gatttaatct gattgttttg aaacaatttt agtgaaaaaa gggtagataa aaacgatgag
     3001 aaaatttttt tatatccggg tcagtagtta tgatcaatcg atcgaacgac aactgatttc
     3061 cgcgaaggaa ttaggaatcc ctgaagaata tatatttgta gaaaaagcca gcggcaaaga
     3121 ttttaaacgc cctgaatatc aattaatgaa acggatgttt cgaaaaggag atttactcta
     3181 tctacaatca ttagatagac taggcagaaa taaacaaatg attttagaag aatggcgaga
     3241 attaactaag gaaaagcaga ttgatatttc tgtgttagac atgcctctgt tagatactgc
     3301 tagttacaag caactagatg ggttagagac gcttatctct gacttaattc tgcaattact
     3361 cagctatatg gccgaagacg agcggaaacg aattaatagc cggcaaagag aaggcgtaga
     3421 agctgcgaaa caaaagggtg taaaattcgg cagaaagaaa attgctttac ctcctgaatt
     3481 tcctgcgatc tattctgact ggaaagcagg aaagataact gcagtctatg ctatggatca
     3541 attgggcatg aaacgaaata ccttttatcg acgggtgaaa gaatatgaac ataccttgca
     3601 ccacttttct tgatagatat aacagctatt agacgggaag ggagagtttg aaaatggact
     3661 taacgaatca aagggtcgtt tttactggaa cgctgcagca aatgacacga acccaagcca
     3721 tcggtttggt tcactcttta aacggccatt gtcaatcaag tgttacttca aaaacaaatt
     3781 tcctggtttg tggtcagtat tctaagtcgt tgtttgatga ttctctctat acaaaaaagg
     3841 aacaaaccgc gcgggacttg attgcgttag gtcatgagat taccatttta tcagaagtcg
     3901 aattttatgc gttaattagt caacagttga aagaatggca acggtattta taatcgttag
     3961 taaaatttac aaggaggaaa atttttatga agcgaaaatc ttatgatcgt tggggcattg
     4021 aaataactag ttttaatcga aatattgctt ttcacgtgga gtgtgactgt ggggaattag
     4081 caaaaagtgt ttatcaaaaa aattactttt actgtcctaa atgccatcgc cgatacgggg
     4141 tacatggaac atagaaacga aatagtgcgg tagaaaagcg aatgaatgta gtatatttct
     4201 acaaatcatt cgctttcttt attttataaa tagttggtcg agagatcccg ttttcttttg
     4261 caatctctgc aactggaatg ccttgcttta acatgtccac cacggtttta aaaactaagc
     4321 gtttttgcgg atctgttgag ttaatagaat actcgattgg tcgtccctta tatcggccgg
     4381 ctttttgagc caataatact ccttgccgct gacgttcacg aattttctca cgctcgtttt
     4441 gtgcaatata acttagcagt gataaaaaca tatcgaacat agcggtatcc aggagttcat
     4501 ttccagtatt aaaatctaaa aactgtgcat ctaatatttt taacgctact tttttctgtt
     4561 tcataaaagc aactgtattt tttatatctt cataatctct tcctaaacga tctagtgatg
     4621 taacgatgac gcaatcacct tcacggatat aatttagtaa tttttgaaac tcaggacgct
     4681 cagtatcttt accactggct ttttcttgga ataatttatc aatgttaagt ccttccatca
     4741 ttgccaattg tcgatccaaa ttttgatctt gtgaagatac tcgaatatag ccaatttttc
     4801 ccataaaaaa ctccttttta aaagtgatat aatttacatg taaaatttac ttgtagtttt
     4861 actgctatca tagcattttt aaaaataaat tttatgtaga cttaaaattt acttcatgga
     4921 gggtttaaat ggatgaaatc aaaagtaaca aaaaagcatt tggcatttat ttaggagaac
     4981 ctagtacaga acaattaaac caattttttt atttgcatga aaaagattta gaattgatgg
     5041 agactatacg acgaccagct actagattag gttttgcact acagttagtc tcactacgtt
     5101 ttttaggaac ttttatatta gatcttacca atattcccca aaatgtattg agttatgtag
     5161 caactcaact aaatattgat cctggagaaa ttatctacta tagcaggaga cagaccaggt
     5221 atcagcacac aaaattgata aaatcacatt atggatatca agatttcaac caaccggaaa
     5281 tagaaacata cctagctaac tggcttttaa atagagcgct gtatacaaca gaatcttcag
     5341 atatgttgtt tgatatgctt ctaaaaaaat gtctggatga aaagattgtt ttacctggaa
     5401 ttactacttt ttctcgtttt gttgctagtg caattgaaaa agctgaagag catttatacc
     5461 gacaattgtc tttggttcca actgaagatg agagaaagcg gcttctcaat catttagaat
     5521 taattggaac tccagtttat ggggcaataa tcaaaatgga cattttgaga accccgttag
     5581 ctgacgatag tcataaagaa atagccagag gttttgaccg actaaagcaa tttcaagctt
     5641 tctctactga aaaatggaag atggaatcta ttcctgaagg gaaaataaaa gttcttgcaa
     5701 attatgcatt taaagctaaa gctcaattaa ttcaacgaat gagtgaacag aaaaaactgg
     5761 cgttgttagt ggcatttatt ttcatataca aacgtaaggc tatggatgaa caaattttag
     5821 cactatctaa tttttttgaa actgttttta gacgcgccaa aaataaggaa tctaaagaac
     5881 gtcttcgtac cataaaagat ctagatcgag ccgcatcgac actttcagat attgtagatt
     5941 tagtaatgtc cagtcattct gatactaatg aactatccct tcgcgatcgt atcttagaaa
     6001 aatattctga ggaaaatgtt accgaagctg tatcgcaagt tcggctattg gttaaaaatg
     6061 atcgtgaacc aatagccatt tctgaacttc tgaacactta tcgaaagttc agaaaattta
     6121 ttccggatat tttaactaca ctaacatttg acagcaatga ctacggtaac aactgtaagg
     6181 aactctggac cttcattaat aatagatttc ctaagccgat tacttacaaa atgtttggag
     6241 ctattaaaca tactcttcca aagaaatgga tttattacat tcatgaatac cctgaacaaa
     6301 ctaataaatg tgtattgatt gcagctgtcg aattgttaat tcaatcttta aaacgccatg
     6361 atatttatat tcctcagagt gtcttatata acaatcctat ggattgcttg attgatgaga
     6421 aaacttgggt tcaacaaaaa tacgttttat tagaacaact agatcttcct tcttcagcaa
     6481 atgaaatgtc tttatggtta aagaacgatt tggaactgtc ttataaagaa gcgctaaatc
     6541 gttggcctac ttctaaaatg gccagaatag aaaatgcaga tcgcctggtt gtctctagac
     6601 ttaaaaagac atatgaaaaa aaggaagata agtcttttag acgtcgcatt cagcagttac
     6661 ttcctaaaat tgatttgtca gatttgttat tggaagtaaa ccaacagtta aatcttactc
     6721 aatcatttaa ccacttaagt gacaaggaca ccaaaatgaa agacttggat attagtttat
     6781 tagcagttct tttatcagag tcctgcaata ttggtttttc cccggtttca aaagaaggat
     6841 ttgattcttt aaagtatgat cgtcttgtct atgtcaatca tcattatatt cgagtggata
     6901 cactttcagg agctaatcaa aaaataatac atgcacacag gaaacttgcc acctctaaga
     6961 tatggggtga tgggcatatg gcttcagctg acggtattcg ttatatcaca ccacaacgtt
     7021 ccctatattc tagaagtaat ccaaaatatt ttggccgtgg tcgtgggatc acattctaca
     7081 attttgtctc tgatcaatat atagggttcc acggaatggt cgtttcaggg acactgcgag
     7141 attcgcttta ccttctagaa ggattcctca atcaacccag cgaattaact cctaatcaga
     7201 tcatgactga tacagctggt tatagcgata tgatttttgg tctctttggc ttattagggt
     7261 ttcaatttag tccaagaatt gccaatgata aaggaaccaa actttggcga atcgacgcta
     7321 acgctcacta cggggaactt gatacgttgt ctcaaaattc aattaatatg gaactgattt
     7381 atacccattg ggaggacatt cttagggttg caggttcgtt gaaatctgga aaagtgaatg
     7441 caacagaatt aacgaaatct cttcaacgga atgggcaacc cacgccttta ggaaaagcaa
     7501 taactgagta tggaaaagtt tataagacga aacatcagct tcgttatatt tctgacgaaa
     7561 tatatgcacg gcaaatttta gaacaattga ataaggggga agctcggcat gccttatgcc
     7621 gtaatatttt ttatggacga aaaggaaaac tctaccagac ttattatgat gggatggaag
     7681 agcagctcaa tgcattagga ttagttacta atgccatcat atattggaac tcactgtatt
     7741 tagaaaaagt atttgaacaa atgaaagctg aaggattcga ctgttccgaa gaaatgatac
     7801 gcaggcaatc tccactaatt agtgatcaca tcaattttgt tggtaagtat acgtttagat
     7861 acgaagctga attatccaac ggtaagttac gtccattgaa tgtagaagaa ttctagcaat
     7921 gttcgggttt tgcatgctac cgcactattt cgtatgactg ttccagcgaa tcacttcgaa
     7981 tagaaaaaga gaaaaacacg agaacagcgt taaatcaacg tttcttgtgt ttttactttt
     8041 gtgctaccgc actatttcgt ttctatgttc catgtacccc tttatcaaga agcgcaaaca
     8101 cgccaaattg ccgattggtt gatcggcatg aacgcaagcc ctttatatac cttgaattta
     8161 caacaaaaag gcgtacaagg tacattttca ttaggacgtg tacaaacacc gactttatat
     8221 ctcatttatc aacgccagga agcaatagaa aactttaaaa aagaaccttt tttcctgaat
     8281 aattcatagt tttactaata gtctttccta acattgattt aatagtctt
//
LOCUS       DAXLPY010000092         8291 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.093, whole genome shotgun sequence.
ACCESSION   DAXLPY010000092 DAXLPY010000000
VERSION     DAXLPY010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.093"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            674..1900
                     /locus_tag="ACF3UF_002426"
     CDS             674..1900
                     /locus_tag="ACF3UF_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3672495.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFKEITGISSEKFQKTFPTRQLAIKA
                     ENEMKKKIAKVLREENANSLELKGQIKFKEFYKSKWLPRYELGQTTRSHKAPSDITII
                     NTKNLFRLHILPIFGEYAMSYLNANTEIISDELTKKSKEYANIKIIKCYVRSMFDIAE
                     VLNYIEFNRTTKIIQSITAPKKVALEEKRIREGKQALSSKELTDWLDAVRDDFNDQLL
                     SFHDYTLFMLTLYLGDRKSETYALQWKYIDFENQTVRLKYALDKHTKKKFTKGRKDTI
                     IQVPEIVMTLLQEWKSVQAEQLLKLKIKQTPDQYLFSYSKPSGEVNCPVHTDYLNYRI
                     NSIKKRHPHLVHLTPHKLRHTYATLARQGGADMNQISNALTHSGISTTKIYVNTPDLV
                     DKAVFEAFQRGLQKSN"
     gene            complement(2058..2675)
                     /locus_tag="ACF3UF_002427"
     CDS             complement(2058..2675)
                     /locus_tag="ACF3UF_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672496.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTLKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
     gene            complement(3358..4353)
                     /locus_tag="ACF3UF_002428"
     CDS             complement(3358..4353)
                     /locus_tag="ACF3UF_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3672497.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
     gene            complement(4448..5320)
                     /locus_tag="ACF3UF_002429"
     CDS             complement(4448..5320)
                     /locus_tag="ACF3UF_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3672498.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNKLLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            complement(5333..6760)
                     /locus_tag="ACF3UF_002430"
     CDS             complement(5333..6760)
                     /locus_tag="ACF3UF_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFD3672499.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEVKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            complement(6814..8088)
                     /locus_tag="ACF3UF_002431"
     CDS             complement(6814..8088)
                     /locus_tag="ACF3UF_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3672500.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
BASE COUNT         2746 a         1524 c         1185 g         2836 t
ORIGIN      
        1 attttaaatt tttacatacc tgtttatgaa aaactaaata atctgtcaaa aaaatatgat
       61 tgttcatttc taaatatgtt ttccaatttt aaaatctttt ttagcatttt tgtttccttt
      121 tcatatggtt tttcgttgtt aatagtgact aggatgatat tcctattttg accattgaca
      181 attaaatata atttttgaat aacgttccct gctattcgag ctaagaattc aagtacgcca
      241 tgacctattt agcgataact acttagagat ttctttttgt tttgggaaga caaaatgcca
      301 tgacaatagc agtagataat gatacttccg taaggctcgc cgtaaactgg ggagaggtga
      361 aattcctatg tgcttaccca agtcaattca aaaattttag ttcatttata aggggatgat
      421 tttattaaat caatagtcta tctaaacaaa aaacaaacct gtgagttttt aggaattgat
      481 aacaatactt tagataaatg gattcgtata tataattttc ccgtaataaa aatagacggt
      541 ataattcgct ttgatgtaga agatatcaaa ggctttatgg atacgttcaa aaagatttga
      601 attttacttt tgactgcata tactaaaagt agcgaaatat actgccttac ttttttatta
      661 aggagtgagg aagttgccta cgaagctttc aaatggaaaa tataaaacta atttgagata
      721 tccaaaaaaa tttaaagaaa ttacaggtat cagttcagaa aaattccaaa aaacatttcc
      781 aactaggcaa ttggctatta aagccgaaaa tgaaatgaaa aagaaaatcg caaaagtctt
      841 aagagaggag aatgcaaatt cattagagct caaaggtcaa ataaaattca aggagtttta
      901 taaatctaaa tggcttccta gatatgagtt agggcaaact actagatccc ataaagctcc
      961 aagcgatata accatcatta atacaaagaa tttatttcga ttgcatattc tgcctatatt
     1021 tggtgagtat gccatgagct atcttaatgc aaataccgaa ataatatcag atgaactcac
     1081 aaaaaagtcg aaggaatatg caaacataaa aatcattaaa tgctatgttc gttccatgtt
     1141 tgatattgca gaggttctaa attatattga atttaatcgt acaacaaaaa taattcaaag
     1201 tattactgca cctaagaaag ttgctctgga agaaaaaaga atacgagaag gaaaacaagc
     1261 tttatcttcg aaagaactca ctgattggtt agacgctgta agagatgatt tcaatgatca
     1321 attactttcc tttcacgatt acactctttt tatgcttact ttatatcttg gggatagaaa
     1381 gagtgagacc tatgctttgc aatggaaata cattgatttt gaaaaccaaa cagtccgtct
     1441 taaatatgcc ttggataaac acacaaaaaa gaaatttaca aaaggtcgaa aagatactat
     1501 tatccaagtt ccggaaattg taatgacact attgcaagaa tggaaatcag tgcaagctga
     1561 acaactattg aagttgaaaa ttaaacagac acctgaccaa tatcttttta gttactccaa
     1621 accttctggt gaagtaaatt gtccagtcca tactgattac ttaaattatc gaattaattc
     1681 tataaaaaaa agacatcccc atttggttca tttaactcct cataaacttc gacatactta
     1741 cgcaacttta gctagacaag gtggggctga tatgaatcaa atttctaacg ctttgacaca
     1801 ttcaggtatt tcaactacaa aaatttatgt gaatacacct gatttagttg ataaagctgt
     1861 gttcgaagcg tttcagcgag gattacaaaa atctaattaa tgtgttctag aatgtgttct
     1921 aaatataaaa aaaagacact ttccaaataa ttggaaagcg tcttgaacgt tgatatataa
     1981 aggatattaa cgttttgaga attgagatgc tttacgagct ttcttaagac ctggtttctt
     2041 gcaaaattat attagcctca actgaaagat ttattttttt gctccctaac ttcattagta
     2101 ataccatgtt tcattcgata tcttctaaac gttctacgat taatccctgt tagctcttca
     2161 acttctttat ctgtagatcc agtcaaaaac aaattaaatg ctaattgaag tcgcggatca
     2221 ttctcacgat attttagcgt acctcccttg tatttccctt ttgctttagc gagtgcaatt
     2281 ccttgttgtt gcgtttcgcg aatataccga cgttcttctt cggcctggta cttgtatagt
     2341 tcgataatta agttattaag taatcgacgt aaattatcat cagtgatacc tgttaacgct
     2401 ggcaaattca aaacttccag tgtagctttc ttcagctgaa ttaaattcat cgtttctgtt
     2461 agctctttat tatttcgtcc aagtcgtttt aattctgtca caacgacaat atcaccttca
     2521 cgtatgaatt tcatcatttc ttgaaatcct tctcgattgg tatctttccc acttgcttta
     2581 tcactaaaaa ttttatcaca ctctgataat aattctaatt gtcggtctaa attttgatct
     2641 aagctgctta ctcgagcata cccaattttc gccataataa aactccttta aaattctgaa
     2701 atccggatca tttttaaatt ctgttgccca actctgttgt catttttcta gataaatggc
     2761 ataaattttc agcgctaagt gacaaaagca actaattttt catgatagat ttttaaatat
     2821 ctcaatctat ctccaaaatt agttgctttt gtagctatag ttgactatga atatgacaaa
     2881 taattagaaa aaactgtgcc aattaaatat aaaaatgaca ctcatttaca ttcaatagaa
     2941 caccaagagc ccaacagggt atactctggt gtccttttaa aaaagtaact ttctgaccta
     3001 attaattgag ctactaaaaa agctatgaaa tgaggaataa aaaagggatc aaaaactttt
     3061 aagtttctga cccttttgag ttctaattat ttcttccaga acgaagaatg ttatctgctt
     3121 tatctgcaat tgattctgtt agaaggactg aaaaatttat gccagccctt ttgcctagct
     3181 tatccgccca ttgaggaatt gttaaggttt ttctgacaag ttctatgtct ttcaaatatt
     3241 tggcaacatc tacacagatt aaaagcatga ttttgtatca tagtctatta taagagattt
     3301 aacaattttt tatatcacga attaataatg aaattatcat tgatagtctt tataaattta
     3361 attgttcttt ttctttactg atgtcttccc catccataat gtgacaggta aaatatattc
     3421 cttttttgtt tcttctttat ttattcgttt catcaaaata gcaacagctg tgtctgctat
     3481 atcattaatt ggttgtatta ctgttgtcag atctggtaat atactccgag tcattaaagt
     3541 accatcatat ccgactacta ataaatcagc tggtacattt aacccctttt cttttgctac
     3601 ttgtaatatt agggccgcat cgatgtcatt tgaagcaaaa ataccatcta ttttaggata
     3661 atcctcaaac atttggaaaa aaatctgttt tttctttaca taagaaatat tgaaatctaa
     3721 tgtcacagtt cgtggaatta actgatatgc tttcatagta tcttcatagg ctagtctccg
     3781 acgattagcc ggagtctgta agtcaattgg accgtttgta tgaataatat tttttgcacc
     3841 ttgtgcaatt aataacttgg ttgcaagttt tccaccattg tagttatcgg attcaacaac
     3901 tggaatatct tcattcatca ctcgatcaat tgcaacaatc ggtaaattct gatatttata
     3961 ttcctgaatt ccttggttat gtgtaccaac aattaaacca tctacttgat cagacaataa
     4021 ctgatttaaa taatttgttt ccttttcttt attattcatc gaattgccta ttaatacctt
     4081 ataaccaatt tcatataact ttttttccaa tgcctcaacg agttcactaa aaaaaggatt
     4141 ggctactgta ggaaatagta acccgacaat gttagttttc ttttgaaata attgacgcgc
     4201 tacaacgttc ggttgataat tgagttcttc tatagcctta taaacattat caatcgtttt
     4261 ttgacttaaa tagccacgat tgtttaatac acgtgaaaca gttgtttttg atacatttgc
     4321 tcttttggca acatcttcta attttgggcg cattctcttg tctctcctaa ataatgcaat
     4381 aattaactat cgaaaaaaag aactctatag aactactata cctgataatc gatatttttt
     4441 ctatgtttta ttcttgtaat tgattcaagc ccaaagcaaa gtttcctagt gttgccgatc
     4501 cattattttt aattaaagga cgcgtaatat atttacttaa cggtggtatt tccacgtaat
     4561 catccaataa tttattaaca ttaacacgaa ttttttctaa caatttttca tttactacgc
     4621 ttccaccaaa tactatttta tccggtcgta taatcaatgt tgtttgaatc acagcttgtg
     4681 ctagataata ggccattaca tcccaaatag gatccgttaa agaaacgtct tcaccctttt
     4741 ttccaaaacg tgcttcaaac gttggtcccg caactaagcc ttctaaacaa tcaccatgat
     4801 aaggacaaat tcctttaaaa tcaatatcat caggatggcg ttttacaaac gtatggccca
     4861 tttctgaatg accaaacgat cctaatagtt ttccgtcaac aacagctcca ccaccaacgc
     4921 cagtaccaac ggtgtaataa actaatgaat ttattttttc attcgataaa gtggacatga
     4981 tgtactctcc ataagctgat ccgttcacat ccgttgtcca agacattgga acattcagct
     5041 catcttgtaa ataacctaac acattaacat ttcgccatcc cacctttggt gtagacgtaa
     5101 tatatcctga ttttggtgaa ttttttcgaa tttctattgg accaaatgat gcaataccta
     5161 atgcatttat atcaaactgt ttaaaatagt caacagtttt tttcaatgtt tccctggggg
     5221 tggtcgttgg acaaattatt tggtcttgta ctcggtaatc ctcgtctccc acggcacata
     5281 caaatttagt cccacctgct tctatgctac caattaacat cataaaacct ccttactcgt
     5341 aagaaattgc atcttttttt agatgataaa ttgtactcga gacaaaagct tcttcactaa
     5401 cactcaaatg catacttggt tgattttctg tataataacg ctctgtaaaa acaagctcgc
     5461 catcattaat aaaaatctct gccgaacttt tatcgataaa cactcgaagt gataatctat
     5521 cacacatctg aatggttcca taccttggat catttttgcc gttacgagtt aaggtacatt
     5581 catttttatc cttagaataa aaaatattga ttaactcttc atcttttgtt tttaatgaaa
     5641 atttgacttc ttgatttttt gatttagtca atagtacatc aattagagct tctttgaatg
     5701 aagcatcttg agcgattatt atttctcctg ccaaattaac tgtcgtttca acgccgctgc
     5761 caactcgaag ttgttctaat tctctcacag gtttcatata caaacgatct ccaattaact
     5821 ctaattctcg aggaagcgtt aatgctcctg cccatccgtc tactttttca ggcatagggc
     5881 tttcccacat atccatccag gccataacaa tacgtctacc atctggagat aaagttgttt
     5941 gtgttgcata gaaatcgtgt cccttatcta attcataaaa atttcctcta atgaattttg
     6001 ctgtctcata atcataatca ccgataaagt agcctgtttc atatagattt aaataatctt
     6061 ttccatttgc ttcaattccc tgaggggata ataaaagaat agattttcca tttaattcaa
     6121 aaaagtctgg gcattcccac ataaatcctt ctgtaagtac ttccttcgct ttagaaattg
     6181 gtccaatgta atcccaattt aataaatcta acgactgata aacaatagca cgacctaatc
     6241 catctttttc ttgactaccc aaaaccatgt aatatttttc atcgtgtttc catacttttg
     6301 gatctctgaa atgatgtgtg ttatcttctg gtgcttttgc tattacagga tttttttcat
     6361 atttagtaaa gtgaatgcca tccgtactat acgccatgtt ttgattttgc caaaaatgat
     6421 ctggatcatt gtctccataa tagtgatgtc ctgtatagaa cagatacaac acaccatttt
     6481 tttcaatagc gcttcctgaa aaacaaccac cttcatcttc ttgatctcca ggagtcaaag
     6541 caagtggtaa agattcccaa tgaactaaat ccttacttct agcatgtgcc cagtgcattg
     6601 gtccccattc agcactatat ggatgatgtt gataaaacac atgataatac ccatcaaaat
     6661 agcaaaatcc atttggatca ttaatccatc ctgatggtgc agacacatga tatcccaaac
     6721 gataacgtgt atttgttaat tctatagctc tttttgtcat aatatattcg ctcactttct
     6781 agataaaatt gttttttatt ctgttggttt ccattatcct cgaataaatg gatccccttg
     6841 aacatctcta tcatcttgtt taagaataaa gaatgcatat atgcctgcta gtaatacaat
     6901 aagagaaata attttaaatg ttggttgata gccaacgttg tctcttaata ttcccaatgg
     6961 tgttgataaa atcacttgcc caatttgagc agctatctga aatcctatca tatagagggt
     7021 tgctgatagc tttgtatcaa aatgaagtgt aaaatagcga aacattggta atgtaaataa
     7081 tggtacttct aaagcatgca acatttttat gcatgaaaca gataatggtg tcgaggcaaa
     7141 cccgcacaat ccaattcgta cacacataat ggttacacct aataacaaag tatttcgaac
     7201 ccctaatttt ctcataatga ttggaacaat tcccatcatt aacgcttcac aaaatacttg
     7261 aatagcattc aatgtcccat atattttttc accattagct gatgttgaaa acaaaccagt
     7321 ataaaatccc ggaaacattt gttgatcgaa taccgtataa aatgtccatg taaaaacaat
     7381 aaagatgatt atcgtccata attgaggcag tttcattaga tcaaacattt cttttaaaga
     7441 aggaatacta tttgattcag cttgttcttg attaaaattt tgatttgctt cccgttcaac
     7501 tttagggttc caaaataata aatttaacaa tagtaaagaa ccaaagaaag atcccgccca
     7561 aaagtttaaa tgaggatttt ttacaaataa aaatcctgcc aaaagcgcta ccaaggcata
     7621 accaaatgat ccccacgccc ttgcttgtcc atattcaaag ccaaataaac gactaaacct
     7681 ttctgacaca gcttcaaaaa ctcctacaga agctaaatat ccagctgaca aaaatagcgc
     7741 tcccataata atgcctaaat taaaattgtt atctagcaat ggcccatata tccatataaa
     7801 aaatggtcca acaagtgtcg ctaatacaga agcaaaaatt aataaatttc gtttaatata
     7861 caatttatct tgtaatgttc cataaataaa catcaaaatt aaggtaacta acgaatttgc
     7921 cgagaatact gttcctacag cactgccaga taaccctaaa ccatttgatt cagatgttag
     7981 ccaaagttga aaaaatgacc accaaacacc ccaagaagca aaaaatagta ataatgtagc
     8041 tgaactttgt aaataagatt gatttttaaa tacgttaact tttgacatat ttttatcctc
     8101 caacgatata tttgtatccc ctttcatgat aaccggttaa catttttaga aaaggacttg
     8161 tactcctaaa attataaaag aaatccgctt acatgtcaac cggttattct atttggataa
     8221 tgccatataa tgtcacagga tatgactttt attggtgtgt cgcttttctt ttttaatggc
     8281 actatttttt a
//
LOCUS       DAXLPY010000093         8238 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.094, whole genome shotgun sequence.
ACCESSION   DAXLPY010000093 DAXLPY010000000
VERSION     DAXLPY010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.094"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..265
                     /locus_tag="ACF3UF_002432"
     CDS             <1..265
                     /locus_tag="ACF3UF_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672501.1"
                     /translation="GLTNFEILLELKNEIIRLNMEDDLSMTKFQNYSKSKHLPSVYTI
                     MRRTNKTWEELMSEIGYDYKEIKIKKQRNNLRCRSKKICSRYE"
     gene            694..4287
                     /locus_tag="ACF3UF_002433"
     CDS             694..4287
                     /locus_tag="ACF3UF_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3672502.1"
                     /translation="MIRNKKLCLKVALLAVFCQVFFLVGSLTTQAEEITQGTTVSQVS
                     PTSNEVEVQSDLPKETAKEEISTEFVPPTEAPSMNEKSVLDETIGKSQQPGDSPVVAE
                     EIPIETPEVQTIFEKENSSEKSCSTVINEGTESVQSEDSKEATTPIELTKEEMNSNTS
                     LSSEKEEKTALSTESHEPELKKVEESGDTQKEKIKKEAVSSTSSKEVTLIVPQTARSA
                     RVRRATNTAVLGGRKIDWGENIGVISSANNPNFTLNYMVRFEINGQVAFCIEPGVAAA
                     EGQVYTATALENYLKDLNIRKKTSLISYLGYVTSKDKSDEQYIAAQFMIWEVLGTKIP
                     IKNIRIDYDRRKAEIQRLLNNFDVRATFHNQTHTVKIGETLKVKSGNDFLQRVKDIQK
                     PKGVNVSIHDNEVWITITKESPEKAKIHFNQIEALGVPLAYRRPGAQTIGVLNPFVPG
                     DSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQANGKKIKEITLKNING
                     KVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNTIAKDQVIKGTIDLV
                     KVANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTVVFDTY
                     ILSETKGKEGYKLFEPFEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKVIALAG
                     TQFKIWDKYANNGKGGYVSMALPNDTEVSDIFTTNEKGYFVTTDTLKYGKNRYELREI
                     KAPEKYVLNKTPYVFSVTDDTNTIQLIYFANRLAKANVEVFKYDTSTNFDQKTAIAGV
                     EFDLFKKDETGTTFVGTFKTDKKGKINVKDLLVGDYFFKEVKPLAGYLALDKDVPFTV
                     TVDKDGTVIALEVENKRIPPKIGTTAIGKYTNQQKVTPLKKVTITDTVKYSNLIIGKT
                     YTVNGVLMDKEESITAGKDVPLLVNGKQITASKVFVAKNPNGMISLDFVFDASALAGK
                     EIVVFENVYRDGRLVASHTDIHDKGQTVRIVNPMIHTKATGQNGEKQLQALPNQKVKE
                     LVQLNDLIVGQTYKVLVQGYITPDGVKLDGTSAEKIFKADKTTLEFLFEFLVDGRKLA
                     GKGLSFAEWLEAQSEPKDENDYEVRFEQIANHNVDLKSEDQTVYFVEVPKVPEPKIPE
                     KSQPFKEVKQASVVPMLPKTGSEDTVLWMIIGVLFVLAAGLTFYELRKVKD"
     gene            4387..5325
                     /locus_tag="ACF3UF_002434"
     CDS             4387..5325
                     /locus_tag="ACF3UF_002434"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3672503.1"
                     /translation="MKKKERKKRMKKLFFACLFSSVVLAGGINVFADEIGITPVTPPV
                     IEETTPVVPIPDISKIDESVPDQPTPVDPDISSEVTEPTTPVVPDITENSENETPVVS
                     PSTGETTNDKDTTPTTSESYSGTSSVDNDSKIDDFSSSSTTIDTPKETEKKNDLGAPK
                     NLTPENHIKTVSEKEMTVSVSSDGKIVQGTGTEKSIPIVTSNLEEINHVPTSETPLQV
                     ATGQAIVGVQDGVPLVQDNQGNLVEDLSIPVKKLPSGNIEIKTIDGKTKVLPKTGEEL
                     QISLTILGSLLTAVTGGIFYGKKQWRHLRHMFKKTI"
     gene            5344..5694
                     /locus_tag="ACF3UF_002435"
     CDS             5344..5694
                     /locus_tag="ACF3UF_002435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672504.1"
                     /translation="MGLSYVAISQEEVLGKCFNQKHVGSTGERDHRGNMKKVEWEIFQ
                     MNSEKMGEIEVRVAVGGAPKAMRYNAEVLLANPRISRRADVRNIGNDGETNKIARNRF
                     YLLVDRVEVKGGNN"
     gene            5694..6125
                     /locus_tag="ACF3UF_002436"
     CDS             5694..6125
                     /locus_tag="ACF3UF_002436"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF961 family protein"
                     /protein_id="HFD3672505.1"
                     /translation="MTLEFDQGIVPGLVKETLGEIYFVKAQRPRMLYEDNENTGEIKE
                     RPVEFSSATQETMFVVNFPPKTNLDGLSFGDVVELEEVEFRFWISIDRESMSNRAEND
                     LKVSALRYKKTGKNVFQTSSSTRATYVKEKQDSNKESAKKE"
     gene            6393..7712
                     /locus_tag="ACF3UF_002437"
     CDS             6393..7712
                     /locus_tag="ACF3UF_002437"
                     /inference="COORDINATES: protein motif:HMM:NF013727.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFD3672506.1"
                     /translation="MFQYKGIRIRNRHKYASERFIFYLMLPVLLLMSGFFSLFYTTIT
                     WEWCCIYWIIAFGLAGLFAYMCLYFYFYNVYQRLVHKGKLAKMIHSRRLILERVLKNG
                     RRKVVYYPKIFYHYKNGLIHVRLPLDLGPFQDRFNEMAGQLEEAFFCDLVEEQREKNY
                     ICYTFLYDVEKNRIGIRDITVKDGIITLMKNVQWAFNKAPHAIIIGSTGGGKTYFIMS
                     LIYALLPYGTFDICDPKRADLASLEKIPIFKDQVFYGGGILSCLINLAKETANRYDFL
                     REQPEYELGYDYTYYHLTPHFLVIDEWAAYYASLDTKEKKKAMGCLNQIALMGRQCGV
                     FLILGTQRPDTKYLDGAIRDNFGLRVTLGRVSKAGYKMIFEHTVKSLFNKPIKGRGYI
                     DSGTDQVREFYAPFIDITRFNFFAEFKQLSDQLMAEKIKETKEGKNV"
     gene            7705..7869
                     /locus_tag="ACF3UF_002438"
     CDS             7705..7869
                     /locus_tag="ACF3UF_002438"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672507.1"
                     /translation="MYEEIPATCGTRLGIKDLMIDSFLAIVFSEKRLSFFINKKVENR
                     WRVERMYPTS"
BASE COUNT         2989 a         1215 c         1639 g         2395 t
ORIGIN      
        1 gggattaact aattttgaga tacttttaga gcttaagaat gaaataatta gacttaatat
       61 ggaagatgat ttatctatga caaaatttca aaactattca aaatccaaac atcttccatc
      121 tgtatataca attatgagac ggacaaataa gacatgggaa gaattgatga gcgaaattgg
      181 gtatgattat aaagaaataa aaataaaaaa acagagaaat aatttgcgtt gtagatcaaa
      241 aaaaatatgt tcaagatatg aataaacaaa gtatttttca gcatattttt atctgtacca
      301 ttattttaaa tatccatagc agtttattca tgatttatga ggtttaaaat acaatactga
      361 attcactgct tattttcatg ttactgctta aactttgtat tttaatagaa aatagagatg
      421 tgaacgaaaa atatttattt ctattacaaa aggtaaaaaa tttgatttaa aagctaaatg
      481 tacagatgag ttttgaattt ttctccttca aattcaaaat gagagtagta ggtatgatag
      541 aaatatatca aatattaaga tagatacaat atgcataata ggctatgctt ctttagattt
      601 tttgattaag aacacaataa atagtttacg tcgatactta ttaagttatc gacgtttttt
      661 ttataaaaaa tttataaaag gaggtttctt gatatgataa gaaacaaaaa gctttgcttg
      721 aaagttgctt tattggcagt tttttgtcaa gtattttttt tggtaggctc actgacaaca
      781 caagcagaag aaataactca aggaacaact gtttctcaag tttctcctac ttcaaatgaa
      841 gttgaagtac aatccgattt accaaaagag actgccaaag aagagatatc gacagaattt
      901 gttccaccaa cagaagcacc ttcaatgaac gaaaaaagcg tactcgatga aaccatcggt
      961 aaaagccaac aaccaggaga tagtccagtt gtggcagaag aaataccaat agaaacacct
     1021 gaagttcaaa caatttttga aaaggaaaat tcatcagaaa aaagttgttc tactgtaata
     1081 aacgaaggaa cagaatcagt tcaatcagaa gattcaaaag aggcaacgac tccgattgaa
     1141 ttgacgaaag aagaaatgaa ttctaatact tcactttctt ctgaaaaaga agagaaaaca
     1201 gctctttcga cagaatccca tgaacctgaa ttgaaaaaag ttgaggaatc aggtgataca
     1261 caaaaagaga aaataaaaaa agaagctgtt tcttctactt cttcaaaaga agttacattg
     1321 attgtaccac aaaccgctcg aagtgcacgg gtgcgacgtg caaccaatac agcagttttg
     1381 ggtggtcgga aaattgattg gggcgaaaat attggtgtta tttctagtgc caataatccc
     1441 aatttcactt taaattacat ggttcgtttt gagattaatg gacaagtagc attttgtatt
     1501 gaacctggtg tcgcagccgc agaaggtcaa gtttatacag ctactgcttt agaaaactat
     1561 ttgaaagatt taaatatacg aaaaaaaaca agcttgatct cttatttagg atatgtcaca
     1621 agcaaagaca aatccgatga acaatacatt gcggcacaat ttatgatttg ggaagttttg
     1681 ggcacaaaaa ttccaattaa aaatatccgt attgactatg atcgtcgaaa agcagaaatt
     1741 caacgtttgc ttaataattt tgatgtaaga gctacttttc ataatcaaac acatacggta
     1801 aaaattggcg aaacgttaaa agtaaaaagt ggcaatgact ttctacaacg tgtaaaagac
     1861 attcaaaagc caaaaggtgt taatgtatct attcatgata atgaagtatg gattacaatc
     1921 acaaaagagt caccagaaaa ggcaaaaatt catttcaatc aaattgaagc attaggcgtg
     1981 ccattagcgt atcgtcgtcc aggtgctcaa acaattgggg tgctgaatcc ttttgtacct
     2041 ggtgactctg ttgtcaattt gaccattttg aaacaaggaa acattcgcgt ctttaaagaa
     2101 gatgcagaaa ccggtgtgaa agcacaaggt gcagcttctt tagaaaatgc agtgtatggc
     2161 ttgtatcaag caaatgggaa gaaaatcaaa gaaattacat tgaaaaatat caatggcaaa
     2221 gtacaggcag aaatcaaaga tcttgatcct ggtaaatatg ttttaaaaga gatcaaagca
     2281 ccaaaaggtt atgtactttc tgatgaagca attgaaatcg tcgttgaacc tggaaaaact
     2341 gtcaatacga tcgcaaaaga tcaagtgatc aaaggaacca ttgatttagt caaagtcgca
     2401 aataaagatt tagtcgattc aaccaatcca gacaacaaac ccaaattagc tggtattgaa
     2461 atctctttga cgtcaaaaac aactggaaaa gtggtgaaaa cagttgtgac agataatgat
     2521 ggttacgcta cttttggtaa aaataccgtt gtctttgata cgtacattct ttctgaaacc
     2581 aaaggaaaag aaggatataa actatttgaa ccattcgaag tcacaatttc tgaaaatgga
     2641 caaaccttcc attatgtttt agaagacaaa gtaatcgaac aacgtcttaa agtggtgaaa
     2701 gtggatcaag aaacagggaa agtcattgct ctagctggta cccaattcaa aatttgggat
     2761 aaatacgcaa acaatggtaa aggtggctat gtatcgatgg cattaccgaa tgatacagag
     2821 gtttcagaca tatttacaac aaacgagaaa gggtactttg tcacaacgga tacattgaaa
     2881 tacggaaaaa atcgttacga gttgcgagaa atcaaagcac ctgaaaaata tgttctaaat
     2941 aaaacgcctt atgtcttttc agtaacagac gacaccaata cgattcaatt aatctacttc
     3001 gctaaccgtt tagcgaaagc caacgtagag gttttcaaat atgatactag tacgaatttt
     3061 gatcaaaaaa cggcgattgc tggtgttgaa tttgacctat tcaaaaaaga tgaaacaggc
     3121 acaacctttg ttggtacatt caaaacagac aaaaaaggta aaatcaatgt gaaagactta
     3181 ttggttggcg attacttctt taaagaagtg aaaccattag cagggtatct ggccttagat
     3241 aaagacgtac catttactgt aacggttgat aaagacggta cagtgattgc actagaagtg
     3301 gaaaacaaac ggattccacc taaaattggt actacagcta tcggtaagta tacaaaccaa
     3361 caaaaagtga ccccattgaa aaaagtaacg attacagaca ctgtaaaata cagtaatcta
     3421 atcatcggaa aaacttatac cgtcaatggt gttttgatgg ataaggaaga atctatcaca
     3481 gcaggaaaag acgtaccgtt gttagtaaat ggtaaacaaa ttaccgcaag taaagtgttt
     3541 gtcgcaaaaa atcctaacgg aatgatttcc cttgactttg tctttgatgc tagtgcatta
     3601 gctggaaaag agatagtcgt atttgaaaat gtctatcgtg acggacgctt agttgcgtct
     3661 catacagata ttcacgataa aggacaaacg gttcgtattg tgaaccctat gattcataca
     3721 aaagcaacag gtcaaaacgg cgaaaaacaa ttacaagctt taccaaatca aaaagtgaaa
     3781 gaattggtac agttgaacga cttaattgtt ggtcaaacgt acaaagtgct cgtacaaggt
     3841 tatattacac ctgatggtgt gaaattagac ggtacaagtg ctgaaaaaat tttcaaagca
     3901 gataagacaa ctttagagtt cttatttgaa tttttggtag atggacgtaa gctagcaggc
     3961 aaaggattat cttttgcaga atggttagaa gcccaaagtg aaccaaaaga tgaaaacgat
     4021 tatgaagttc gatttgaaca aatcgcaaac cacaacgtag acttaaaatc agaagatcaa
     4081 acggtttatt ttgtagaagt tccaaaagta ccggaaccaa aaattcctga aaaatcacaa
     4141 ccttttaaag aggtgaaaca agcttcagta gtaccaatgt tgccaaaaac aggatcagaa
     4201 gatactgtat tatggatgat cattggtgtg ctatttgttt tagcagcagg tcttacattt
     4261 tacgagttac gcaaagtcaa agactaagta ggacaaacaa gcggttagat gcctaatcgc
     4321 ttgtttggtt ttaaaaaagt tattgcataa gtaacctttg aaaagataag aaatgatctt
     4381 tgttttatga agaaaaaaga aaggaaaaag agaatgaaga agctattttt cgcatgttta
     4441 tttagttccg tagttcttgc tggtggaata aacgtttttg cagatgaaat aggtattaca
     4501 ccagttacgc cacctgtgat agaagaaaca acacctgttg ttccaattcc agatatttct
     4561 aaaatagatg agtctgttcc ggatcaacca actcctgttg atccggatat atcttcagaa
     4621 gtaactgaac caacaacacc tgttgttcct gatataacgg aaaattcaga aaatgaaaca
     4681 ccagttgtat cgccttctac tggagaaaca acgaatgata aagatactac accaactacc
     4741 agtgagtctt attcgggaac tagttcggta gataatgatt caaaaataga cgattttagt
     4801 tcttcatcta ctacaataga tacaccaaaa gaaacagaaa agaaaaatga tttaggagct
     4861 cccaaaaatt taacacctga aaatcatata aagactgtat cggaaaagga aatgactgtt
     4921 tcagtcagtt cagatggaaa aattgtacaa ggaacgggta ccgaaaaatc aattcctatt
     4981 gtgacaagta atttagaaga aattaatcat gtcccaacat ctgaaactcc tttacaagta
     5041 gcgactggtc aagcgattgt tggggtacaa gatggtgtac cacttgtaca agataatcaa
     5101 gggaatttgg tagaagattt atccattcct gtaaaaaaac tacctagcgg caatattgaa
     5161 atcaaaacaa tcgatgggaa aacaaaagta ttgccaaaaa caggtgaaga acttcaaatt
     5221 agtttaacta tccttggttc tcttttaaca gcagtaaccg ggggcatttt ttatggtaaa
     5281 aaacaatggc gtcatttgcg tcatatgttt aagaaaacta tttagtaagg agagagaata
     5341 aaaatgggtt tatcttatgt tgcaattagt caggaagaag tattgggaaa gtgttttaat
     5401 caaaaacacg ttggctcgac aggtgaacga gatcatcgag gaaatatgaa gaaagtagag
     5461 tgggagattt ttcagatgaa ctctgaaaag atgggagaaa ttgaagtgcg tgtagctgtc
     5521 ggtggtgcgc ctaaagccat gcgatacaat gcagaagtgt tactggcaaa tcctagaatt
     5581 tctcgtcgag cagatgtacg aaatattgga aatgacggtg aaacaaacaa aatagcacgt
     5641 aataggtttt atttgttagt cgatcgtgta gaagtaaaag gaggaaataa ctaatgacac
     5701 tagaatttga tcaaggaatt gtcccagggt tggtaaaaga aacactagga gaaatctatt
     5761 ttgtcaaggc acaacgtcca cgtatgctgt atgaagataa tgaaaacaca ggagaaatta
     5821 aagagcgtcc agttgaattt tcaagtgcta cccaagaaac aatgttcgtg gtgaattttc
     5881 caccaaaaac aaatttggat ggattaagtt ttggcgatgt ggtggaatta gaagaggttg
     5941 aatttcgatt ttggatttct attgatcgcg aatcaatgag taaccgagca gagaatgatc
     6001 tgaaagtatc tgcgcttcgt tataaaaaaa cgggaaaaaa cgtttttcaa acgtcttcct
     6061 ctactcgtgc aacatatgta aaagaaaaac aagactcaaa taaagaaagt gcaaagaaag
     6121 agtaatggtt tccattgctc tttcttattt taaagctaga agaagtagct gatgtggaga
     6181 aaattgaatt ggctggctat attattggga taaatttttg aatttttaag aatttagata
     6241 gtggttagat acgattgatt ctttgtgtat tttgtattat ttaagtattg tgtggtattt
     6301 acattaagtt aatattgatg ttgttagtgt taatgaaggt tttcttttat ccaatacatt
     6361 agtcactcta tgatgcgagg agatgagaat aagtgtttca atataaaggt attcgtattc
     6421 gaaatcgaca taaatatgct tcagaacgat ttatttttta tcttatgttg ccggttctgt
     6481 tgctaatgag tggatttttt tctctctttt atacaacgat cacatgggaa tggtgctgta
     6541 tttattggat aatcgcattt ggtttagctg gtctatttgc gtatatgtgt ttgtattttt
     6601 acttttataa tgtttatcag cgattggttc ataaaggaaa attagcaaag atgatacata
     6661 gtcgtcgatt gattcttgaa agagtattga aaaatggacg gcggaaagtg gtgtattatc
     6721 caaaaatttt ttatcactat aaaaatggct taattcatgt tcgattgcca ttagatttag
     6781 gtccctttca agatcggttt aatgagatgg ctgggcaact agaagaagcc tttttttgtg
     6841 atttagtaga agagcaacga gagaaaaact atatttgtta taccttttta tacgatgtgg
     6901 aaaaaaatcg tattgggatt cgagatataa ccgtaaaaga tggcataatc accttaatga
     6961 agaatgttca atgggcattt aataaagcac cacatgccat aattatagga agtactggcg
     7021 gtgggaaaac gtattttata atgtctttga tctatgcatt attaccgtat ggtacgtttg
     7081 atatttgtga tccaaaacgt gcagatttgg ctagtttaga aaaaatacca atttttaaag
     7141 atcaagtttt ttatggtggt ggtattttat cttgtttaat aaatctagct aaagaaactg
     7201 ctaatcgata cgatttttta agagaacagc ccgagtatga attagggtac gattatactt
     7261 attatcatct aactcctcat tttttggtga ttgatgaatg ggcagcatat tatgcatcgt
     7321 tagatactaa agaaaaaaag aaggcaatgg gatgtttgaa ccaaattgct ttaatgggtc
     7381 gtcaatgtgg cgtgttttta attttaggta cccaacgtcc agatacaaag tatttggacg
     7441 gcgcgatacg agataatttt ggtttacgtg taacactggg aagagtatcc aaagctgggt
     7501 ataagatgat ctttgaacat acagtaaaat cattatttaa taagccgatt aaaggtcgtg
     7561 gttatattga ttcgggaacc gatcaagtac gagaatttta tgcgccattt atcgatataa
     7621 caagatttaa cttttttgcg gaatttaaac aactatctga tcaattaatg gctgaaaaaa
     7681 tcaaggagac gaaagaggga aaaaatgtat gaagaaatcc cagctacatg tggaactcga
     7741 ttaggaataa aagatttaat gattgactct tttttggcaa ttgttttcag tgagaagaga
     7801 ttaagcttct ttatcaataa aaaagtagag aatcgttgga gagtagaacg tatgtatcca
     7861 acgagttaac tgattggtta cagttgcctt atgacaatta tcgaaggcga atatgacggg
     7921 tttttacttc aaataaaagt gctcgatcct atagtgacca aattgtcgaa aaagcagcgg
     7981 aacagcctgt tttttatgga cgattcaaag gactttcctg ttcttatgtt aaaagtaaag
     8041 accggtctcg actgtaccta caagtagagg atattaactt gtcctttgcg ttgccagaaa
     8101 attaaatttg tcctcattag aatacggaag atgctgtgcg tatgctccac aagcaaacaa
     8161 gcctcagggc ggaaggacgc ggaagcgtcc tagcgttagc gaaagccctg aggtgcaggg
     8221 tgcgttgtgg ggcgtgcg
//
LOCUS       DAXLPY010000094         7844 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.095, whole genome shotgun sequence.
ACCESSION   DAXLPY010000094 DAXLPY010000000
VERSION     DAXLPY010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7844
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.095"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            70..2397
                     /locus_tag="ACF3UF_002439"
     CDS             70..2397
                     /locus_tag="ACF3UF_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HFD3672508.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2394..3308
                     /locus_tag="ACF3UF_002440"
                     /pseudo
     CDS             2394..3308
                     /locus_tag="ACF3UF_002440"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            3381..3896
                     /locus_tag="ACF3UF_002441"
     CDS             3381..3896
                     /locus_tag="ACF3UF_002441"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFD3672509.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            4024..5322
                     /locus_tag="ACF3UF_002442"
     CDS             4024..5322
                     /locus_tag="ACF3UF_002442"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3672510.1"
                     /translation="MHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYP
                     SKDTAVPADATPFASVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLS
                     LPFYNPNSSDPDKPLDTIHLYAKNVIKESNIKIQKAGNFSGVDKLAGAQFQIKNSENQ
                     FVTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVETKAPDGYQLTNPQ
                     KETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTITVENVQNYGDFHF
                     IKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWSDEVTGSDWEEVKL
                     ISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDDDPTTSDETTIDNQ
                     PKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            5528..6700
                     /locus_tag="ACF3UF_002443"
     CDS             5528..6700
                     /locus_tag="ACF3UF_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3672511.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6862..7536)
                     /locus_tag="ACF3UF_002444"
     CDS             complement(6862..7536)
                     /locus_tag="ACF3UF_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672512.1"
                     /translation="MKKLVALFLVAGSLLSGCGATTSTTQSTSSAQASSSSTTISEST
                     ADSSKEQEQIEKKKEEEKQKAEKAALEKKVTEAESALSQAEANPTKENYATASAAIQA
                     LPENKQELTSRLAAIDSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQ
                     AAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPC
                     SKCYGN"
BASE COUNT         2669 a         1454 c         1551 g         2170 t
ORIGIN      
        1 aaaataataa aaattaaatt tagaataacg tgtaaaggat tatttgatga ttttttattg
       61 agaggaggga tgaaaatgat taagaaaact caaaataaaa tccaacgtat atgtcaaaaa
      121 cattttgttt ctagactcaa agctgtatct aaaagaaaat acttacatcc cattatgatt
      181 tcgatcatct tgatttttac tttcttaggg agcttatcaa gtatttatgt aaacgtttat
      241 acagaaacgt caaattttgc taaccaaacg acagaggaga caaatagtcc accctattct
      301 gaaatacagt ccatagaaag caccaatcag tctagcaaca acgagacaac ctcaaccaca
      361 tcctcgactc aactgattga tccgacagaa aaagaaatca cagcagcaaa agcagcaggg
      421 gagaaagctt attcagaaac aggtagaagc cagacattta gtactgttgc ggccactgcg
      481 aatttcaacg gacataccat accagatgga tatacagtga tatatgccaa agatggagtc
      541 attgttgcgg ttaacggatc gatgagtgcg gataaaactg cgttacaagg cgtaaccaaa
      601 gcaatcgctt ttattgataa ccgtccagat atccataatc tgtttattgg ctccacagta
      661 aatggtacta ctatcacatt cccaaaaagt atctatatgg gggtggctac cgctggaaat
      721 acgatcgatt cagttacacc caatgcggat aaaagttatt cttttacacc ctcaacatgg
      781 ggagggcttc ctgccggagg aggtatgagt actttttcaa tcggtataca gttagcaaat
      841 gatattccat tcacggggta ctcgatcaaa aatgggcaga tcgttgatgg taagggaaat
      901 gtttcaaatt ttccaaccta tcaagcagca acggttcagg tcaatgcgaa tcggacagga
      961 actttttctt atacagtcaa tggtggagca gcaaaaatcg gaacgtacgg gactacatta
     1021 tctggaatcc atgtgggtga caaagtggtt atcactccaa cagcagtaac gggctattct
     1081 tttgcacaaa caaacggttc tttcacagcc ctagaaagta acgtcgatac ggtgacctat
     1141 acaggcaaac aaacaccaat cactattaag tatcaagact attttggaca gatgattgct
     1201 ccttctaaaa taatgaatct tacttacgga agtgctgcac aagacctgac gactaatacg
     1261 cctactatca acggatatac ctttacagct gtttcagcga cagaaacaaa gaaccaatca
     1321 gcaatgagtg ttttagctag tttagataca aatggaaatg taatcgtaaa ggacgcaaat
     1381 ggaaaacaga tttctgaagt catcctatat tataagacaa atgcaacagt atcaatcaat
     1441 gcaaatggca gtaagtacta tgatggtctt tctgttgtac cgatcgttaa atatgccttt
     1501 aatgataaaa cagaatcaac atccctttta aacaatgatc tcagtattga tcaaatcaca
     1561 tggaatccaa ctgatttcaa agcgatgaat gaaaagggag ttgaagtaac tgcgcctact
     1621 gaaattggaa cctatacgtc ttggcaattg acaaaaagcg gactagctaa actagctgcc
     1681 agaacaaact atttatttac tatcgtgcag acatctgatg tctatacgat taagcaaatc
     1741 agcggtgcgg tagagctcag tggcagtaag acatatgatg gaaaagcagg tgtcccgtca
     1801 atccatgtca agctagcaga gggtgtcact agttcgctta ctccagtaca agtggcactt
     1861 agcagtatgg attacacagc agatgcacaa tcagcaaaaa atatggttaa tgctggcagc
     1921 tatacaatta aactaacgaa tagcggaata gacaaagtca aagcagcaaa tcccaagttg
     1981 tcatttactg atatagccaa cacatcagga acttatacca tctataaagc taacgcagtg
     2041 attactgtcg atgacgctgc ctttaattat gatgcccaaa gtcactcgat ttcggttgga
     2101 aatctccacg ttaccggtgt tgtcttaggc gaatcattgg attataccct aacagttaac
     2161 agccggacag atattggatc acaaatagta acgattagtt taggcgaagg aagtgtaaac
     2221 aataattata cgattatcgc aacagatacc gctaagttga cgatcaatcc gactctcttg
     2281 cttccttcga caggtgggat aggtctactg ccctttgtct ttttaggact gatctttatt
     2341 ttttctggct tcttttattt tatccatcgt aagaaaaaag caggtgaaca gcgatgaaaa
     2401 aaacaaaaaa tgtacgtgtg gatatatttg ctgttctctt ttttatccta ctggtctttt
     2461 ttataggttc tccgactgtg tcagctagag aatcacctat tacatttact ttgcataatc
     2521 gaatgttcga aagcgataag atgccaagta tcagtcaaaa cgacggaata aatatcccgg
     2581 ataactttca aggagtaaaa gggttgaacg gcgttacttt cgctatatat gatgtctcgg
     2641 atgaatttta caagctgcgg tcagaaggaa gtagtgtgga agacgcacaa agaaaactag
     2701 cacaaaaaag tgatagtgaa aaaatactgg cagaaaatgt gacaaaaaca gtagacgagg
     2761 aagagggcat tgcttctttt agtgcatcgg acaaagatga gcaaggtcgt gacgctgttt
     2821 accgatttgc ggaaataaag acttcagatt aagtaaaaga aaaatcagca ccatttgtcg
     2881 ttgtgcttcc tgtgacagat tcatctaatc ataaattgac gaccatccac ttgtatccaa
     2941 agagcgaaca aaaaatacct gctgcactca cattaacaaa aacagtagag aataagcaga
     3001 cagattttgc agatggggat aaagttcctt atctcatcac cgtaacaatt cctgagaaca
     3061 tcaacgagat aggaacctat acgatcaaag atacagctga tcctcagtta tggctagaac
     3121 cagaaacgat cgattttttg attggtggag acaagattca tacatttcac acacaaaaaa
     3181 caaaacatgg ttttgtctta tcagattctg gaaaagatct tagttcgttt gctgggaaaa
     3241 aattaacgat ccgttaccaa atgacattga aagaaaacag tgaaaaaacg acatttgata
     3301 acgatgtacg tttgacgact gacaatcaaa cagtagaaac acatcttgcc atccaaacag
     3361 gaggcaaaca atttgtcaaa gtggatcggc aaacgaaaca aaaactagca gatgctcaat
     3421 ttctagtcaa aaaaaatgac caatacttag cgcaagaaaa cgggataaat cattgggtag
     3481 ccaaagatga ttcaagagca acgattttta cttccagtaa agatggaaca ttttctgtcc
     3541 atggattgtc ttttggaagt tacgaactag tggagattaa accgcctaaa ggatatatat
     3601 tgagtcaatc aaccattctc tttgaagttg aaaaaggcag ttatgatccg cttcatccta
     3661 taccattgga aatcatcaac gaaccaaaag caaatccgac gaataatgga aaaacgccag
     3721 ttcagatgca gacaaatggt ccatcaaatg aaaaaaatgg aggaagcttt ccaaaaacaa
     3781 gcgaagagat gcttggaggt ttctcaattt tagggttgtt gctagtcctt tcaacaggga
     3841 cagcttggtt ttataaaaaa caacaaaaag gaaacaatag gagggaaata aaatgaaaaa
     3901 catcaaaaca aaaatatgga cgtttttagg aactgctatc atgctgcttc ctttcgttct
     3961 cggcctagga actgcagagg tttctaggcc gtatcaccta caccagaaaa tgttacggtt
     4021 aatttgcata aattgaaatt cacttcagca ccagaaaatc aaataaacaa cggaacggaa
     4081 ttgacatttc cgaatagcga accgttgaac ggcgttgaat tcaacgtata tgacatcact
     4141 gctacgtact atccaagtaa agacacagca gttccagcag acgctacacc cttcgcaagt
     4201 gtaacgactt ctggtgaagg attagctaac ctgactcttc caggtaaatc tgatgggaaa
     4261 gatgctgtat acgtctttgt agaaacacca aagcccggtg tcgaaacgtc gccaaatatc
     4321 gtgttaagct taccctttta taacccgaat tcatcagacc ctgacaaacc tttagacacg
     4381 attcacctat atgctaaaaa tgtcatcaaa gaaagcaata tcaaaatcca gaaagctggg
     4441 aacttttcag gggtagataa gttagcaggg gcgcaattcc agatcaaaaa ttcagagaat
     4501 caattcgtga ccggttttga tgaaaacact ggtgtcgctc tctatgatcc tgctgagtca
     4561 gcgttgacat tcacaactga tactgaagga tccatcagtg tcaatggatt aatagacggc
     4621 aattatactt tagttgaaac aaaagcacca gatggttatc aattaaccaa tccacaaaaa
     4681 gaaactactt ttatagtaaa aaacggaaaa ttgcaacaaa caaccggtat catccatggc
     4741 gcagatgaag ccaatcttgg gaatccaaac ggtgtagtca atcgggaaaa tacaactacg
     4801 gataacacga ttactgtaga aaatgtccaa aactacggtg atttccactt catcaaacaa
     4861 gatgtgaaca cgcaagaaaa attagccgat gcagaatttt ctattctaag agcaaaagat
     4921 ccaactgtta aattaatgaa aaaaatagca aatcttgcct caggagaata cccatatgct
     4981 tggtcagatg aagtcacagg ttctgactgg gaagaagtga aattgatttc tgattcagaa
     5041 gggaaatttt caatcgaagg gctgaaacaa ggggcatact gccttcaaga aacaaaagca
     5101 ccagaaggct acgcattacc taagaatgaa gctgcgtaca ctgaatttac agtagatgat
     5161 gatccaacaa cttctgatga aacaacgatc gataaccaac ctaaaggaat cttgccttca
     5221 actggtggta tggggatcat cgtattcatc ttggtaggta ctgctttagt tggaggagca
     5281 gtgatctact tcaaaaaacg ccatcaagaa acagaagctt aaactattgg aaacaaaaat
     5341 catacgataa ataaacgata gtgattcaaa tggggagaaa ggttgtgaca agtggtcggt
     5401 ctcttggtat tcgctcaaca aacggcaaaa taggaggaac tattttgccg tttgttgagc
     5461 gaatactcag gtcaaggcgc tgatttcaca acctcttcat atacatatta gaaaataggt
     5521 ggacatgatg aataaaagca gaataagaat actggacatc ttcatggcaa tcattttagt
     5581 cgttgggatc gggatctttt cttatccttt tgtagaagat tcactgaatg attttcttgc
     5641 ccagcaaatg atcatccatt atcaaaagca agcatcgaat aagaattcag aggaaataaa
     5701 aaaacagcag gaaaaaatga caaagaaaaa ccaacagttg gcagagcaaa acgtatcacc
     5761 agggataggc agtttcaacc aagcagttga tgcaaaagca ttaaaagatt tacctagtaa
     5821 tgcctttttt atggaacata tgcttggagt catcgaaatc ccaaaaatca atgtcagctt
     5881 acctatattc gatcagacaa cggaaatatt tttgcaaaaa ggaacgtcat tattggaaga
     5941 aagttcttat ccgactggcg ggaaaaacac ccatgccgtt ctttctgggc atcgtggact
     6001 cccagaagca aaattattta cagatttgcc taagttgaaa aaaggagacc agtttttcat
     6061 ccagatcaat ggaaagacat tggcgtatca agtagaaaaa atccaagtgg tcttacctga
     6121 tgaagtagat tctttgggta tccaaaaagg cagagatctc gtgactttgc ttacctgtac
     6181 tccttatatg gtcaatacac atcgactgct tgtgacgggg catcgtattc cttatcaagc
     6241 aaaagaggca aaaaaagcga tccaaggaat tgatcaatgg aaaaaatgga aattttttat
     6301 ttggtttatc ggtatactac ttggatcaat cggcttagtt tggctactca tcgcttattt
     6361 agattctttg gccatcgcta agcgaaacta tcctttatct ttttatgtaa agaacacaaa
     6421 cggacgacca atcgaaggaa tggtcttttc tgtaaaaacg ctcaacggca aacactatat
     6481 tactagagaa aaagttccat ttgtgaaagc ttctgatgaa tacggactag tgagattttc
     6541 tgatttaaaa ggcaggaact atcgcttgca acatgaggag ctcctgctta aaatccatgt
     6601 aaaacataaa cattcgaaac agttttcaat gaaattgaaa aaaggaagat ataaactgcg
     6661 aaaagaaaaa gaggtgtact atttgattga gaaagaatga atgaagatgt ccaaaaaagc
     6721 agagggaaca gactaaatga aaaaagagag aagctgacga aatggacgtg taaactgcta
     6781 tttttggttt actatctgga acgccagctt ctattttttt atgtttcaga agaattttat
     6841 tattatagta taacttttga attagtttcc ataacatttg gagcaagggg ttaaaccacg
     6901 agcttgagct tcgcttaaag tggcaggggt atacgtacca tttccacatt tatgtgtatg
     6961 gtattttgaa ccggtcggtg tgacatagac agtttgttca ttattttgct caggagctgc
     7021 ggcttgtgcc tgctgagagg cctgttcagc tgctgcttgc tgtcgcgcct gttctgcttg
     7081 ttgctgtgcg attgcttctt gttgcgcttg ttctgcttgt tgtcgtgcaa tttcttcttg
     7141 ctttttccgt tcttcttctg cttcttttgc tttgattgtg gaatcaattg cagcaagacg
     7201 gcttgtcaac tcttgtttgt tttcaggtag cgcttggata gctgctgaag cagttgcata
     7261 gttttctttt gtaggatttg cttcagcttg tgacaaagca gattccgctt ctgtcacttt
     7321 tttttctagt gcagcttttt ccgctttttg tttctcttct tcttttttct tttcaatttg
     7381 ttcttgttct ttcgatgaat ctgccgtact ttcggagatc gtggtactgc tgctggaagc
     7441 ctgagctgaa cttgtgcttt gagtagtaga cgtagtagca ccacacccac tcaacaaact
     7501 tcctgcgacc aaaaacaatg caactaattt tttcactaaa tttcctcctt aagtaaaaaa
     7561 caaccgtttt caataaatgt ccttttcaat tgtttactta cttgttataa taattgtgtt
     7621 atgaatagtg attgaggaaa cttaatctaa tcccgttttg atacacggga ttttttgcta
     7681 tagttctgtt attaagtatg caataataaa atatgtacgt tattttatta ttagattatt
     7741 gacatttata taataaacga ttaaatgatt catatcaata gaatacttag gaaaaaaaga
     7801 gaaataataa caggtttatg cactattgac ggtgtgacaa tatg
//
LOCUS       DAXLPY010000095         7628 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.096, whole genome shotgun sequence.
ACCESSION   DAXLPY010000095 DAXLPY010000000
VERSION     DAXLPY010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.096"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(17..715)
                     /locus_tag="ACF3UF_002445"
                     /pseudo
     CDS             complement(17..715)
                     /locus_tag="ACF3UF_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            794..970
                     /locus_tag="ACF3UF_002446"
                     /pseudo
     CDS             794..970
                     /locus_tag="ACF3UF_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1146..1715)
                     /locus_tag="ACF3UF_002447"
     CDS             complement(1146..1715)
                     /locus_tag="ACF3UF_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3672513.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1789..2112)
                     /locus_tag="ACF3UF_002448"
     CDS             complement(1789..2112)
                     /locus_tag="ACF3UF_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672514.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2266..3078)
                     /locus_tag="ACF3UF_002449"
     CDS             complement(2266..3078)
                     /locus_tag="ACF3UF_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672515.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3405..4280
                     /locus_tag="ACF3UF_002450"
     CDS             3405..4280
                     /locus_tag="ACF3UF_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3672516.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4294..4617
                     /locus_tag="ACF3UF_002451"
     CDS             4294..4617
                     /locus_tag="ACF3UF_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672517.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4614..5366
                     /locus_tag="ACF3UF_002452"
     CDS             4614..5366
                     /locus_tag="ACF3UF_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFD3672518.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5356..7527
                     /locus_tag="ACF3UF_002453"
                     /pseudo
     CDS             5356..7527
                     /locus_tag="ACF3UF_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2273 a         1512 c         1373 g         2470 t
ORIGIN      
        1 agaggggggg gattttttat cgttgtggaa tatttaaata ccaacgcttg tcatgaaaat
       61 cttgtgctcc acccttagta tttccttctg gatcgtttgt cgcacgcatc atgacgtata
      121 ctttcttatt agggaaatca cgcatattga aagatacatg atagccaaca tttcctaaag
      181 tattataagc ttgatttacg tctggtctat aaatcccatc agctcttact ctagctagtt
      241 cttttccagt attgtagtcc ataatgaaaa tatactcgta tttataatta gcaatgtgcc
      301 atccagctac atgcaagttt gcgttttcga tttctccgaa ctgatcaatg tgggcgtaat
      361 ttgttccatc tgtcagcgta gaatttgcag cacctgctcg agttggatca attactggtt
      421 tatcctccga agtagttgga ttatcatccg taaaaccatg agccaaatca taggctagtt
      481 tttctttact tacacctatt tcagaaagat aaccgtaagg atctgtatga tcgccccaaa
      541 tattttgtgt tacccataaa tgcgatttga ttcctggttg gttataagga gtgtctaatg
      601 ttaatggaat accatatttc attgctgaat ctcttgccaa ttcaacgtat actttatagt
      661 tcttttcaaa agtttcttta tcatgtgtgt gttgtaactc gatttgcaca ggacttttgg
      721 ctcacgaggt tgtcctactc tacatcttgc tgatagatat gctgaaagga aaacaccaac
      781 attatgtttt gctttttcag ctagaacgag acaagcagga atacctttag aagatatcaa
      841 aggtttttta ggtcataaag atgtttccac tacacaagtc tatgcccata tttctcccga
      901 agtgaaaaaa agatcaatga atcaactaga aaactatata gaagagcaaa taaaaaagca
      961 ctcaaattga gtgctttttt aagctcacta tcactaaaac tatcactaat tttatttata
     1021 agcgaacatg tttctatcac tgatttttta aatctagcga aaaaccctta tcttaaaggc
     1081 gttcgttcaa ttctttggca aggtcttcaa agcctggctt gcctagaagt gcgaacatgg
     1141 ttttcttata gctcatgtag aaaaattttc ttgatgatga ttttatccat caattgagat
     1201 tgactgtttt gctctcctat gatttcagct atgattgtcc gattttgcgg ttttcttctt
     1261 aactggtagt tgattttccc agtttccatc aactcgctaa gcatatccac gactccgcca
     1321 aatccggtct ttttcgtaat aaaacctagt gctaccattc gttcatctag attttttgct
     1381 gtaatcgtca caccagtaat gagcgagtgc tgtaatgttt gggccagctc ttccatccct
     1441 tcagcattgg atacgacgga agctgttttg ttaataggtt cttcgtttat ttcttttggt
     1501 tctttcctct ccactttcac tgtttgacga aggacatcta gttcttgcaa gagcgtttcg
     1561 tattgttctt gggtcagcat cacgccagct actttttcac gattaaatat atatacgcca
     1621 gttcccgcgt ctcgcgcttg agcaaataca tccatcggcg atcgtttcac ttctgtgatc
     1681 gaagatgtgg gaacttctaa tttctttaat tccaatggat ttcctccttt actaatcgct
     1741 ttttattata gcacagactg acttgttttg atcttttttc caaaggtttt atcggttttt
     1801 gcctaaccag taattgatat cggtaagaag tctttcgata ccaaatgaag gatggtacag
     1861 atacgttttt tgatcttcgt tatggtctag tggaaaaaaa tgatcgatga tcactagatc
     1921 tgcataccga ggcggcttat ttcgagtaca tacatgtata gagatccgtt ttcgatgtct
     1981 tagcgttttg ttcagtaccc cagcaagtct tcttgcttct tggtgttcat agcgaaaaaa
     2041 aaagacgatt ttcacttcag gagggtggac atctaaatac cctcgttcct ggagtgtttt
     2101 cagtaaaagc atcccccact ctactgcggg gtgtgcaagt gcttgttgga tcgctagccg
     2161 aaattgatat agtttatctt tggaattggg aaatttttct aatgtttcct gataataacg
     2221 aacttcttct atcagccggt catggatacc aattacgtaa cgaagtcatt cttggtaaag
     2281 tacttttgtc agctttgatt tgctttcgct ctcaaattcg ctattcagcc aaaacagcga
     2341 atcaagcttt tcagtcacaa tcgtcaattt ccgatagtct tgtgtctctt ctatccgttt
     2401 ccaccgcttt tcagtaatct ggttacagct caagcgcaaa attgctagat aatttttttc
     2461 ttttattggc aaaatctgct cctctctaaa tagcaattca ggaaacaatt caaagaatag
     2521 tgttcgactg tctcctaaaa tctcgatttc tgccggatcc tttctttgct tcaataattg
     2581 gatgaacatc tcagaaaagg actgctctcc atcatctgca aaaaaatgcg gaaaatcttt
     2641 caaaaagcaa aacagcagat atcttacttt tctttctgaa ccaaagatct gtgctttttt
     2701 ataagaaaaa gaaaggtggt actcgccaaa ccactttctc aatcgctctt gcgtagaacg
     2761 atcgtacttc tgctcgtaag gttcattcaa tagcagattt ttcagtaaac aaaacggggg
     2821 tgattggatc agaaaaacaa acaagagata aggttcgcta tatccttgat cataaactaa
     2881 ctgaacggtt ttcttatgaa gaatcagctg aatgggacag tcgctttccg ccaaacgttt
     2941 cagatgccga tccactgttt taacatcgat tttcagttct tcagctaaat cagcttttcg
     3001 ccagatcaaa tctttcatta gattgattag tgaaaataaa ttctgtgcat tttttgataa
     3061 tagtttttgc catctcatcg atcatttctc acctgatttc taaacatatt gtttgatcaa
     3121 aatgggttca ctcctaaaaa gataaaaaac tccctttcta tttatttaaa tacgcaaatc
     3181 ttcctcatta ttttttattt tactcaattt aatcgtattc tcatttcaaa acgaatgtac
     3241 tttaaaaaaa cataataaga tcactttgct tgtaggatgt attcccttcc attacaatga
     3301 aataaatagc gattttatga gaaggtgatg tgaaaatgga agaaaaaata gaagaatcca
     3361 aacaaaaaat cgatcagttg atataagaat tagaaaaagc ggtcatcggc aaacgttcaa
     3421 ctatccaatt gatgatcgtg gccctattag caggtggtca tgtcttattc gaagatattc
     3481 ccggtgtagg taaaacgtta ctggtcaaag cactagcaaa agctgtacag ggaaccttca
     3541 gcagagtcca atgtactcct gatctgctgc ctagtgatat tcttggtttt tccgtataca
     3601 attcacaatc aaaagagttt gaatttcgtc cgggaccgat ctttaccacg atcttgttag
     3661 cagatgagat caatcgtacg actcctcgta ctcagtcagc acttttagaa gcaatggccg
     3721 agaatcatgc aacgatcgac aacaatacat accctctaga caatcatttt tttgtcttag
     3781 ctacgcaaaa tccaatcgag tacgaaggaa catatccttt gccggaagca cagctcgatc
     3841 gttttttatt ccgactacaa atcggttatc cttcttttga tgacgaactt ttgctacttt
     3901 tggataaatt cgaaaaagtg ttggataact taaatgaagt attgaacagt tatgaaatag
     3961 aagaaataaa aacaaatgtg gcgaatgtct ttgtcagtcc cgaagtggca tcttatgcct
     4021 tgcagttagt gtcagcaaca agaagtcatg ctgccatcca gcttggcatc agtccacgag
     4081 gaagcctttc ctttattcag gcagcaaaag cttatgcttt aatccatggg agaaattacg
     4141 tcacgcccaa agatttgcag gatttagttc cttacgtgtt ttcccatcgc ctgatttttt
     4201 acgatcgttc attgaaggaa gacgaaaaga aacaaatcat tcatactctt gttgcacaaa
     4261 ttcctattcc tgtgaggtag attgaggtag acaatggaaa aaatcaaaga ttatttcatt
     4321 aattttgtgt tatttctggt atatttcatc attgtgcttt ttgctcttgt attcaacaat
     4381 tctttaggct ggttcttgtt ggcctttttt actctttatg tatcatggag cttgatttca
     4441 ttaagcagct ttctaaagaa actttcggtt acttgtacat tgcagccact cgtttatcgc
     4501 aaaaaaagta tgcaggttat tttttccata gcaaaaaaga gaactttttc tttacctctc
     4561 cctcgtttac aaatcggctt cccagcaatc tttgcagaaa aaaacaagag attttgattc
     4621 ttacaaataa accgcaagaa gtccaattgc tttggcagcc aaaagaaaga ggatgccatg
     4681 aaacattaac tgtcattttt acagcctatg atagtctagg acttttcaga aaaagtgcaa
     4741 aaagagagat ctcttttcct gtgactgttc tgcctgcttt ttgtaagatt caagcagaaa
     4801 aattacagag agttctggaa aaaaaacagc agctgaacgc gtaccaaaga ggtcttgatt
     4861 ttcgggaaca tcgcgcttat cgtccaggtg attctttcaa ccgaatcgat tggaaattgt
     4921 ctgctcatac tcaagagtgg ttataccgtg aatacgatta tcaagaagaa gaatgttctc
     4981 ctcttttttg cttttggggt tcgcccagtc caaaatttga acctctgcta gacttgtatt
     5041 tttctttatg gcatttgaga aaagaaaagc agccggaact tctgatatta ggcaaccgcg
     5101 cctttcatgg caaagacccc ggtcatacct attttgcttc tttggaagct ggcgatgaga
     5161 aaactttttt cgcacacttg aaaaaatatg caaaaaaaca aatcgtcctc tttgttcctg
     5221 agaattctcc tgaagtctca gaagctattg aaacattgtc aaaagatcga acggtttatc
     5281 ttgtttattt cgtagaaaaa caactcatgg tccaagaaaa agacaagata tgttcattgc
     5341 caggaggtga atggattgac gattaaacgg gaaaaatggc tgcgtggcgt ttactccttt
     5401 gtgatactaa gtgtaggtgc tccgatattt gtagtagcta atcaattgca aaacagctac
     5461 cttcttatcc taactattgg tgtcctatgc cttattgtct gctgtattcc taaaaaatgg
     5521 gtacgtttgc tgctttcttt gccagtaatg ataggttgtt tgtttttata ttttccttcg
     5581 aagacatttt ccatattatg gatcttacag tttttttcgt cagttacaga ggaattcttc
     5641 catctatccc aaggtaaact ttattatttg ccagaaaaga cagctttttt tctcataatg
     5701 ttgctgatct atttatttat tacattgacc gtggattacg actattggta cgcacccttt
     5761 ctttctttga tggcttactt catgatgctt accgtttttc ggaaaaaaga tttactgtac
     5821 gaaatgattg cggtagtaac tgttttgttc gtgtatctgg cagcaaggca atttttctcc
     5881 atccggttgt tgtcgagaaa cactcgattc cagtcattga ctacagttct gcttatttgt
     5941 ttcttaactt ttagcgctat cttgccttta tatcttccga aagtacacca atctctcgag
     6001 gaaacgagtg aaccgatccg agaatatctt aatgatgaag ggctttatga cacactccat
     6061 gagtatcaat taaccggaag tgcaagaaca ggcttcagtg agaatgatga acagcttggt
     6121 ggacctttat atgataatgg cgaagttgtt tttacagcga accaaaaagg aaatggctat
     6181 tggaagatcg aaaataaaaa tcattacacc ggttctggat gaatagaaga tcaggacgca
     6241 cccatccaac caatccaaga attccctgtt gacatcacga gctaccaaac cgttatagaa
     6301 gacaaagaaa acattacatt gaccctaaaa aaacaagctt tcttacctta tccttatgga
     6361 aatactacct tgactgattt ttcattagct agtggacaaa cgctttacta tttgcctgaa
     6421 agccagcgat tcattcctgt cccgaatgaa tcgacacgtt ctgcaacttt acaaacagaa
     6481 aggttagttt ttacgagaga agaattaaaa agcagtcagt taaaagctga tgatttagaa
     6541 aatcagcaga caaatcttca attgccaaaa agtttgccta aacgtattga ggacttggcg
     6601 gtcgaattga ccaaaaatga agcaacttta attcgtaaag tcgaagctgt ctaacagtat
     6661 ttaaaaacaa gcggaaattt ccgctattcc aaaacggata ccgggcatac tccaaaagaa
     6721 cacgattatg tggattattt cctctttgat tcaaaagtcg gctattgtga caacttttca
     6781 acttctatgg tcgtccttct tcgaacactt ggtatcccag ctcgctggac aaaaggtttt
     6841 acaaatgggc tcagaacagg cacagataat caagggaatg aggaatacag cattctcaat
     6901 agtcatgctc attcttggcc agaggtatac tttcctggat ttggctggct tccatttgaa
     6961 ccaacccctt catttgccaa tccaatgggt tcacaaccag ttgctgaaac aaccgaaacc
     7021 gtccagcctg ctatcgaaca accaaatgaa agcgaaaata tggcagaaac tatttccagt
     7081 gagagatctg aggtcattcc atcagaagaa acaacactca caccagctta taaaatcgtc
     7141 ttattcagcc ttggagtgtg tttatccgtc ttgttgttct ttctattgtt attcagaaaa
     7201 tctctgcgct ggacaagtta tcttatctat cttcattttt ttgcttctac taatacgatt
     7261 gcatatcaaa aacttcttaa ccctttggaa acattggtac cgcgcaaacc cgcagaatct
     7321 ttgcaggaat atagcctgcg aatagaacaa gaattcaagc tagatctgcg tttcattcga
     7381 ttaactactc aatatgaagc agaaatatat ggacgacaag cagatccggt aaaattcgat
     7441 aaaaaaacct atttagaaat aacgcatata ataagaaaaa cggtatacaa aaaaattctg
     7501 acaaaaggga gccgcttcaa aaaataagat aaaatttctg gagaatctac ttctcgaatg
     7561 ccgagaacca gctgattgag tatcgattac tcgaaaaaaa ggttgtgaca cgttttttgt
     7621 cacaacct
//
LOCUS       DAXLPY010000096         7607 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.097, whole genome shotgun sequence.
ACCESSION   DAXLPY010000096 DAXLPY010000000
VERSION     DAXLPY010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.097"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            251..1033
                     /locus_tag="ACF3UF_002454"
     CDS             251..1033
                     /locus_tag="ACF3UF_002454"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFD3672519.1"
                     /translation="MVKKIDFHIHTVSSHKDYDFSYSPEWLKKYVRAAELDAIAITNH
                     DLFDESNFKQIQYDLPNTKVFPGIELSLEEGHVNIIFPEEDSPNLVHFSEWLSTQNLG
                     QNGKVSTEDFCTHMSNWENGIYIFELGKSNALSVPEKLESICSVGGVANQLKFQTFYR
                     IEDALTPVLFSDAHADDNDPEEKRKNIEILKNKNTYLQIDNCSFQEIKNCLMDKTKVG
                     INLRYLRDVIDIENHTVSTGLNLIVGKRGTENQFFRNDKKIL"
     gene            975..2291
                     /locus_tag="ACF3UF_002455"
     CDS             975..2291
                     /locus_tag="ACF3UF_002455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3672520.1"
                     /translation="MLVNEVLKTNFLETIKKYYDYEDIYEIAQFETSNANDFIKKQRT
                     EQGKNALDIWKKRYDSQFSAIQDYLKNNEEDFNQDVEKFVESVKQFAKDSTTSNSTSK
                     YQLIKESNLEEISTKNLETHLYKLLDLINSPDLWELLSNSVEKRRVFVETYSEVRNLF
                     VQKQQNNKVREKVNDILGSVKKIVQSKTGITPVVDCEFSKIIQKHQIEKEINNFMQKI
                     VCNTEIKKEKIYGYQIIVKLSPFINATQFRKDRTSEAVQDDLIVPYKSGQYITFLRNL
                     KKRSFFNPSILEEYLLHLEVNLLDSDGVPASGGQAVGFALMMRLEEAKTKPIILIDEP
                     EASLDNEYIRKELRDAIRNLSASSTVFVVTHNSTLGALLEPDYLIVTTKDKEKGYRVL
                     TGEFSSHLISTKSDTTESSYEKFVEAMEAGIETYKKKGEIYESLNS"
     gene            2272..2556
                     /locus_tag="ACF3UF_002456"
     CDS             2272..2556
                     /locus_tag="ACF3UF_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672521.1"
                     /translation="MKVLIVNSGKSKFVIGENNVEPENLSRDDLLMILNNIYESEENV
                     VIPSIEELDEIRNPIEKEIVQQIIQKISDFSNNVENIRQEVQAQFPVIED"
     gene            2594..2917
                     /locus_tag="ACF3UF_002457"
     CDS             2594..2917
                     /locus_tag="ACF3UF_002457"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672522.1"
                     /translation="MVGIDNDSNFKSYEFEKTYDFSVEIPIVDEDTGEYTREIELVAG
                     QITFFGDADWDSTEKEYVYNFSWEESTRTFSHYGNAPDKEDEFIKDFKEYLLQQGVER
                     YNIGW"
     gene            2968..3192
                     /locus_tag="ACF3UF_002458"
     CDS             2968..3192
                     /locus_tag="ACF3UF_002458"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_component: GO:0030127 - COPII vesicle coat [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0006888 - endoplasmic reticulum to Golgi
                     vesicle-mediated transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec23/Sec24 zinc finger-containing protein"
                     /protein_id="HFD3672523.1"
                     /translation="MTERFPDTDWWCDRCGAHLNSQNNFDDYKYTWKCTECGFKNSIS
                     KDNIYESHEEYYNTGDDDSGLLRSIFKKLF"
     gene            complement(3579..4199)
                     /locus_tag="ACF3UF_002459"
     CDS             complement(3579..4199)
                     /locus_tag="ACF3UF_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HFD3672524.1"
                     /translation="MATKVFISFRFSDGKEIKDELVDLFDESTEVINRSEDVDRSQMS
                     KDTIQEYLYEKLKDTSVTIVLLTPEAVSYRKNWIGNYDDWIYDELRYSLEDRNNNRAN
                     GVVAVYTDDAKDMILESSSHYCAHCQETKSCRTLKSFDNLARKNMLNIKQSYKKNPCN
                     DLYDDSHDSYISLVSLEEFKQDYTKYIDNAKDKRDRLHEFNIYKRM"
     gene            complement(4199..5611)
                     /locus_tag="ACF3UF_002460"
     CDS             complement(4199..5611)
                     /locus_tag="ACF3UF_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFD3672525.1"
                     /translation="MRQELFIKKFSKAIQEGNAAVFAGAGTSVDAGFVNWKNLVAPFA
                     NEIDLDIEKETDLVGLTQYYINKKRNRGSVNQEIIDQFSSQYAETEVMNLLTRLPIST
                     YWTTNYDKVIENGLKNNNRRGDIKRKTDDLAISIRDSDAIVYKMHGDVDSPNDAVISK
                     DDYERYSEKNSLFVTALRGDLVSKTFLFVGFGFEDPNLESILGKIKNLLGERTRDHYC
                     IQKKVLEQDYKNREEYSYAKIKQELKIEDLKRYGIDTVLVDDYSEIPKLILKIEEEYF
                     KNTIFISGSISDYNENWSQEKVNQFCYNLSRSLVSKNYKIISGFGLGVGSSVINGALD
                     EIYNTKYRHVSEHLGLFPFPQHDAGEKSLAKRWTENREQMISEAGICIFIFGNKLVNG
                     EVVLASGMMEEFRIAKERGKVIIPIGSTGFVAKEIFDEMKESGDYSYINDYWNDLENE
                     EDVIKVFNTINEIIEGVRFR"
     gene            complement(5641..6801)
                     /locus_tag="ACF3UF_002461"
     CDS             complement(5641..6801)
                     /locus_tag="ACF3UF_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HFD3672526.1"
                     /translation="MGIVMRQYNNFYIKFQRQFKKAHGQVIETMPLEFSNKEYIERFK
                     YMFPDKILLIERERNYWYGKRIIRKNLSKIRCKGMSLETDSFILSTSKHIRKIKRESL
                     ASNEEMVKKVNTARTISLEKLKAESLRSKRKLNYIQEVEPPYLRNYRNRFFKTHDLHE
                     RLEIIRELSKYDSKEVREFFYAINGHIRNQSLKIEVQSYFQSLSLPFRLSRKKKGKKN
                     FIDNEIVKNKKGPDELKKRLYINDLEKIKRFDIFVSHNSRDEEKIIEFYKKFNKKGQV
                     VYIDWINDKYDLRREWCNASTVDIIKERIKQSDVFVLYFSGETLNSQWCTWELGYADA
                     LGKKICVYFSEDINRKGIPKFYVAYPELQMSKNIYVKIRGNEDILLKEWKKL"
     gene            complement(7207..>7607)
                     /locus_tag="ACF3UF_002462"
     CDS             complement(7207..>7607)
                     /locus_tag="ACF3UF_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3672527.1"
                     /translation="PTEPSKPTEPSEPTEPSTPTEPSTPTEPSTPTVPNKPVDTNPIE
                     NPVNTDTGVVIVAVEDSKPIIQLANGTTKKVEAKEIGANVQKDGTVTVKGSDGKMKVL
                     PKTGDTENIALSVLGSLMVLGSAFIFKKRI"
BASE COUNT         2556 a         1222 c         1118 g         2711 t
ORIGIN      
        1 tattattggg aatcccagct taaatcatag ataccgtaag ggattttatt ctttatttaa
       61 aactttgcaa cagaaccatt tcgaagatcc ttaatttaaa taaattagag gaggatttat
      121 attgccgcaa acaagttcta aaatcaatgt cactgagtgg ttgtttgtat ggcggatatc
      181 aagcatatta gtcagcgttt acatgatata atcaagacat gagtttccaa attattatgg
      241 aggtctacat atggttaaaa aaattgattt tcatatccac acggtttcta gtcataaaga
      301 ttatgatttt tcttattctc cagagtggct aaagaaatat gttcgagcag ctgaattaga
      361 cgcaattgct attactaatc acgatttatt tgatgaaagt aattttaaac agatccagta
      421 tgatttgcca aatactaagg tttttccagg tatagaactg agtcttgaag agggacatgt
      481 aaatattatt tttccagaag aagatagtcc taatctagtt catttttctg aatggctatc
      541 tacccaaaat ttaggacaga acggaaaagt atctactgaa gatttttgta ctcacatgag
      601 taattgggaa aatggaattt atatctttga actaggaaaa agtaacgcct tatcagtacc
      661 agaaaaattg gaatctattt gttctgttgg tggagtagca aatcaattga aatttcaaac
      721 tttttataga atagaagatg ctttaacacc agtattattt agtgatgcgc acgctgatga
      781 taatgatcct gaagaaaaaa ggaagaatat agaaatatta aaaaataaaa atacgtactt
      841 acaaattgac aattgctcgt ttcaagaaat aaagaattgt ttaatggata aaacaaaagt
      901 tggtataaac cttagatatt tgagggacgt aatcgatatt gaaaatcaca ctgtttcaac
      961 tggattaaat ttaattgttg gtaaacgagg tactgaaaac caatttttta gaaacgataa
     1021 aaaaatatta tgattatgaa gatatttatg agatagctca atttgaaaca tcaaatgcca
     1081 atgattttat aaaaaaacaa agaacagaac aagggaaaaa tgcgttagat atatggaaaa
     1141 aacggtatga ctcgcagttt tctgctattc aagactatct aaaaaataat gaagaagatt
     1201 ttaaccaaga cgtagaaaaa tttgttgaaa gtgtgaagca attcgccaaa gattcgacta
     1261 caagtaactc aacttccaaa tatcaactta ttaaagaatc gaatcttgaa gaaatttcca
     1321 caaaaaactt agaaacacac ttgtacaaat tacttgattt aattaatagt ccagatttat
     1381 gggagctgtt aagtaattca gttgaaaaaa ggagagtttt tgttgagaca tatagtgaag
     1441 taaggaattt gtttgttcag aaacaacaga ataacaaagt tcgagaaaaa gtaaatgaca
     1501 tactaggttc tgtaaaaaaa atagttcaat ctaaaactgg gattacccct gttgttgatt
     1561 gtgagttttc aaagataatt caaaaacatc agattgaaaa agaaattaat aatttcatgc
     1621 aaaaaatagt ctgtaatact gaaataaaaa aagaaaaaat ttatggatac caaattattg
     1681 tgaagctatc tccgtttata aatgctactc agtttagaaa agatcgtaca agtgaagcag
     1741 ttcaagatga tttaattgtt ccctataaaa gtgggcagta tattacattt ttaaggaatt
     1801 tgaaaaaaag aagtttcttt aatccttcta ttttagaaga atatctattg catttagaag
     1861 ttaacctgct ggattcagat ggtgtaccag catctggggg acaggctgtg ggatttgctc
     1921 taatgatgag attagaagaa gcaaaaacaa aaccaataat tttaatcgat gaacccgaag
     1981 cgtcacttga taatgaatac attcggaagg aattaagaga tgctataagg aatttgtctg
     2041 caagcagcac tgtttttgtg gttacacata attcaacatt aggagcatta ctggaaccag
     2101 attatctaat agtgactacg aaagataaag aaaagggata tcgcgtactt accggtgaat
     2161 tttcttctca tcttatctct acaaaatcag atacaactga aagtagctat gaaaaatttg
     2221 tagaagcaat ggaagcagga atagaaacat ataaaaagaa aggagaaata tatgaaagtc
     2281 ttaatagtta attcaggaaa atcaaagttt gttataggtg agaataatgt ggagccagaa
     2341 aacctttcta gagatgattt attaatgata ctaaataata tttatgaatc tgaagaaaac
     2401 gtggtgattc ctagtattga agagttagat gagattagaa atcccattga aaaagagatt
     2461 gttcaacaaa ttattcaaaa aatttcagat ttttcaaata acgttgaaaa tattcgccaa
     2521 gaagtgcaag cgcagtttcc tgttatagaa gattaaaatt tatatgctaa taaaaaataa
     2581 aggagtgagg aaaatggtag gaatagataa tgatagtaat ttcaagtcat atgaattcga
     2641 aaaaacatac gattttagcg tagagattcc aattgtagat gaagatacgg gggaatatac
     2701 tagagaaata gaattggtag ctggacaaat aacatttttt ggagatgcag actgggattc
     2761 aacagagaaa gaatatgttt ataatttttc ttgggaagag tctactagaa catttagtca
     2821 ttatggtaat gcacctgata aggaagatga gtttattaaa gatttcaaag agtatttatt
     2881 acaacaagga gttgagaggt ataatattgg atggtaaatg ttgaaattaa ttataaaaat
     2941 ttttaaatat gtagggagag atatactatg acagaaagat tcccagatac cgattggtgg
     3001 tgtgaccgtt gcggggcaca tctgaattct caaaataatt ttgatgacta taaatataca
     3061 tggaaatgta ctgagtgcgg ttttaaaaat agtatttcaa aagataatat atatgagagc
     3121 catgaggaat attacaatac aggtgatgat gattctggtt tactaagatc aatttttaag
     3181 aaattgtttt agtgctgaat tacttacaga ttttctgaga atgccttgaa acgttaatct
     3241 tccggtagtt aaaggagagg taatcacttt tctttttttt acttcattgt tccataactt
     3301 tatccaaggt gattaatttg acatagaact tgtgatggat ttatggacac gtgtttcaat
     3361 tcttttagag aaaaatcata ccaaaatagc agtgtccaga aatgaactat tttatggaca
     3421 tgagataaaa aagaaaaaca gccatttccg tttttctttt ttatctttgt gtctaaatat
     3481 ttgacattag tccaaacaaa agcactttat aaatcttgta cagaaaagtg ttgccttttc
     3541 atttattcta aagacaattt atgctaaatc aatgctcttc acattctttt atatatatta
     3601 aattcatgta gcctatctct tttatctttt gcattatcaa tatatttagt ataatcctgt
     3661 ttaaactcct ccaaacttac taaagaaata taagagtcat gactatcatc ataaagatca
     3721 ttacatggat ttttcttata gctttgcttt atattcaaca tattctttcg tgctaaattg
     3781 tcaaaagatt tcaaagttct acatgattta gtttcttgac aatgtgcaca atagtgtgaa
     3841 ctactttcta gtatcatatc tttagcatca tctgtatata ctgctactac gccatttgct
     3901 ctgttgttat ttctatcttc caaggagtat ctaagttcat cataaatcca atcatcgtaa
     3961 tttccaatcc aattctttct ataagaaacg gcctctggag ttaataatac aattgtaacc
     4021 gatgtatctt ttaacttctc atatagatat tcctgaatag tgtccttact catttgactt
     4081 ctatcaacat cttctgatct attaattacc tcagtagatt catcaaataa atcaactagt
     4141 tcatctttaa tctcttttcc atcactaaaa cgaaatgaaa taaatacttt tgttgccatt
     4201 atctaaatct aactccttca ataatttcat ttattgtatt aaaaactttt ataacatctt
     4261 cttcgttctc taaatcattc caataatcgt ttatatatga atagtcccct gactctttca
     4321 tttcatcaaa aatttctttt gcaacaaacc ccgtagaacc aattggaatt attacttttc
     4381 ctctttcttt agcaatccga aattcctcca tcattccaga tgcaagtact acctcaccat
     4441 taactaattt attaccaaat ataaaaatac agatcccagc ctcactgatc atttgttcac
     4501 gattttcagt ccaacgttta gctagagact tttccccagc atcatgttga ggaaaaggaa
     4561 ataatccaag atgctcactg acatgcctat acttagtgtt ataaatttca tcaagagctc
     4621 cattaataac actactacct actccaagtc caaaccctga tataatttta taattttttg
     4681 aaacaagtga acgcgataaa ttataacaga attgatttac cttttcttga ctccaatttt
     4741 cattgtaatc ggagatacta cctgaaataa aaattgtatt tttaaaatac tcttcctcta
     4801 tttttaatat caacttaggt atttcagaat aatcatcaac tagaactgta tctataccgt
     4861 accttttcaa atcttctatt tttaattctt gtttgatttt agcatagcta tattcctctc
     4921 gatttttata atcttgctct aataccttct tttgaataca ataatgatct ctagtacgct
     4981 ccccaagtaa attttttatc tttcccaaga tggattctaa attaggatct tcaaaaccaa
     5041 accccacaaa caaaaatgtt ttggaaacta agtcacctcg taaagctgtt acaaataggg
     5101 agtttttctc gctatatctt tcataatcat cttttgaaat aactgcatca ttaggtgaat
     5161 ctacatcacc gtgcatctta taaacaatcg catcgctatc acgaatactg attgctaaat
     5221 catctgtctt cctttttata tctcctctgc gattattatt ttttaagcca ttttcaatta
     5281 ccttatcata attagttgtc caatatgtag aaattggaag tcgtgttaac agattcataa
     5341 cttctgtttc tgcatattga ctagaaaatt ggtcaattat ttcttgattc accgaacctc
     5401 tatttctttt tttattgata taatattgag tcagtcctac aagatccgtt tctttttcaa
     5461 tatctaaatc aatttcattc gcaaacggtg ctacaaggtt tttccagtta acaaatcctg
     5521 catcgaccga tgttcctgca ccagcaaaca ctgctgcatt tccttcttgt atagctttcg
     5581 aaaatttttt tataaataat tcttgtctca tattaccctc atttctaatt tattataagc
     5641 ctataatttt ttccactctt taagtaaaat atcttcgttc cctctaattt tgacatatat
     5701 attttttgac atttgcaatt caggataagc tacatagaat tttggaatac cttttctatt
     5761 tatatcttct gagaagtaaa cacatatctt cttccctaat gcgtcagcat atcccaattc
     5821 ccaagtacac cattgggaat tcaaagtttc tcctgaaaag tataatacaa aaacatctga
     5881 ttgttttata cgctccttga taatatcaac tgtggaggca ttgcaccatt cacgccttaa
     5941 atcgtattta tcatttatcc aatctatata aactacctgt ccttttttat tgaacttttt
     6001 atagaactct ataatttttt cttcgtctct agaattatgc gatacgaata tatcaaatct
     6061 ttttatcttt tctaaatcat taatatataa tctctttttc aattcatctg gtcctttttt
     6121 attttttaca atttcgttat caataaaatt cttcttacct ttcttttttc tgctcaacct
     6181 aaaaggtaaa gataaactct gaaaatatga ttgaacttct atttttaatg attgatttct
     6241 aatatgccca tttattgcat agaaaaactc ccgaacttct tttgaatcat acttagaaag
     6301 ttctcttata atttccaatc gttcatgtaa atcatgagtt ttaaagaatc tatttcgata
     6361 attccttaaa tatggaggtt caacttcctg aatataattt aattttctct tgcttctcaa
     6421 ggactctgct tttaattttt ctaaagatat tgttcgggca gtatttactt tttttaccat
     6481 ctcttcgtta ctagctagac tctctctttt tatcttccta atatgttttg aagttgaaag
     6541 tataaaacta tcagtttcta aagacatacc tttacatcga attttggaaa gattctttct
     6601 aataatacgt tttccatacc aataatttct ttccctctct atcagcaata ttttatctgg
     6661 aaacatatat ttaaagcgtt ctatatattc tttattagaa aattctaatg gcattgtttc
     6721 tataacttgt ccatgagctt tcttaaactg tctttgaaat tttatataaa aattattata
     6781 ctgcctcatt acaatcccca tactcaataa gtccccccca ctacttaata ttattttgca
     6841 gtatattgtc ctctctgtct tttttctcaa tgttacacta aaatagattt tttggaaaac
     6901 tttgcaacag aacctatctc gttagttatc gcaccacttt tagtggttct aataatcaca
     6961 ttagttgatc attggttaga tgattagacg atggcaagca agttgctttc taactcacac
     7021 gcttgtattc gcaacaagtg aaaagaaaag ccgacctact agcaatatgt tattggtgtt
     7081 gcctagaacg attctaagcg cttgtttaat tttaaggtat acattcccct tcaaaacgtc
     7141 ctagaatgat tcaataaaag catggctgct agtgaaactt gcgaccacgc ttttataaat
     7201 acttaattag attcgctttt taaaaatgaa tgctgatcct aataccatta atgaccctag
     7261 gacagacaat gcaatatttt ctgtgtctcc tgtttttggt aaaactttca tttttccgtc
     7321 tgaaccttta accgttactg ttccgtcttt ttgaacgttt gcaccaattt ctttagcttc
     7381 aactttcttt gttgttccgt ttgctaattg aataatcggt ttactatctt caactgcaac
     7441 aatcacaacg cctgtatctg tattaactgg gttttcgatt gggtttgtgt ctactggttt
     7501 gtttggtact gttggtgtac ttggttccgt tggtgtactt ggttccgttg gtgtacttgg
     7561 ttctgttggt tcgcttggtt ctgttggttt gcttggttct gttggtt
//
LOCUS       DAXLPY010000097         7603 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.098, whole genome shotgun sequence.
ACCESSION   DAXLPY010000097 DAXLPY010000000
VERSION     DAXLPY010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.098"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(426..1370)
                     /locus_tag="ACF3UF_002463"
     CDS             complement(426..1370)
                     /locus_tag="ACF3UF_002463"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFD3672528.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1666..2610)
                     /locus_tag="ACF3UF_002464"
     CDS             complement(1666..2610)
                     /locus_tag="ACF3UF_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFD3672529.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2831..4045
                     /locus_tag="ACF3UF_002465"
     CDS             2831..4045
                     /locus_tag="ACF3UF_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3672530.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4067..6082
                     /locus_tag="ACF3UF_002466"
     CDS             4067..6082
                     /locus_tag="ACF3UF_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFD3672531.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6165..7538)
                     /locus_tag="ACF3UF_002467"
     CDS             complement(6165..7538)
                     /locus_tag="ACF3UF_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFD3672532.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
BASE COUNT         2364 a         1422 c         1362 g         2455 t
ORIGIN      
        1 taaaaaatga taaacctctc tcgaacggtt ttttatcaaa aatcgtcatt tttccatcaa
       61 aatctgctta tgcaaaatta taaaaaaatt ttgcagtttt tcttactttt tttgtcgttt
      121 aattgaatga taaaaaccag tttctttatt cagttaatca aatatgaacg aattagatat
      181 gaatcattgt atttgccgtt gcggaaggat tttttaatta accacagata aacattgata
      241 acgattcgct tattgtaatc aacagattaa atttcatatg ttcatatgta cggatacatt
      301 ttcggaccga ttaattttaa ccattctgtt tatttgctta cctattagat atcaataaaa
      361 aactgcttaa cagctatttc agctgttaag cagttttagg atttttagtt catattcatt
      421 gtttcttata atacagtgtt caatacttct cttaaagcac ttgttgattt gctgaacatt
      481 gctttttctt cttcgttgat tgataattca acaacttcac gaacaccatt ttcgtcaacg
      541 attgatggca cacctgtaaa gatatctttt tcgtcgtatt caccagttaa ataagcagat
      601 acaggcaata cagcttgttc gttattcaag atagctttta cgatacgtgc agtactcata
      661 ccaataccat agtaagttgc ttttttacga tcaatgatct cataagcagc attacggact
      721 ttatcagcaa tcacatctaa ttcatcttgg gcaatacgat ggtctttttc tacaatttca
      781 aacactggtt taccaccgac agttgtatgt gaccatgcag caacttctga atcaccatgt
      841 tcacctaaga tatagccgtg gacgctgcgt gggtcaactt ttaatttcaa tgcgatttct
      901 ttacggaaac gagttgtatc caatgttgtt ccagtaccga taacacgtga tgttggcaga
      961 ccagattcgt tccaagcgat atatgtcaaa atatctactg ggtttgaagc aacaacgata
     1021 ataccgtcga atcctgatcc catgatttct tttacgattt ggcgcatgat tgacgcattt
     1081 gttttaacta aatctaaacg agattgacca ggtttttggt tgataccagc tgtgataaca
     1141 acgatatcag catctttaca ttcttcatag ccacctgacc atacagccac attttcatcg
     1201 ccccaagcca taccatctaa aaggtccaat gcttcccctt ctgctttttc ttgattcaca
     1261 tcgatcaata ctaattcatt agagattcct tggttgatca ttgcataagc gatacttgtt
     1321 ccaacaaaac ctgtaccgac gattactact ttacgacttg tttttttcat gaataaacag
     1381 ctccttttca taactatttg ttactttcat gaaaagtata gtcttgttta ttcattttat
     1441 caacatgtta attataatag ttgttattat aatttttgat ggaaacgaat tcctgaatac
     1501 gcataacaga taaatgacaa atgtttacac ctatatcccc tgataataca accaaaagtt
     1561 tagaactgaa aataaatcca aaaaaattcg ctgcaacgat ataataagac agcaatcgca
     1621 cctaaaacaa ttttccttca tatgctttag tgaaagattt tcttcttaat gtttatttct
     1681 ccattcattg ggagtacatg ttgaatactt cttgaataat ttgaataaag aagtcgtttg
     1741 tttatatccg atacgattag cgatttcttc caacgaaaaa ctcgtttctt gaatcagttc
     1801 caacgcaaag tcgaattttt tctttagaac cagttcttga aaggaagcat caaaatacat
     1861 tttcaattta ttactaagat agaccggatt gtagccaaaa tgagctgctg tttcttttaa
     1921 cgtacaagaa gtaaaatgct tatcgatata atctaatact ctaagcatct cattttctgc
     1981 gcatccatct gctgatgaaa agctttgttg ttctaataaa tgagtcaatt cgatcagtaa
     2041 tagtgatgta tagagattta acgaacggat cttatgactg tatgtatcaa aataaatcaa
     2101 cagcatattt tcaatcaaat gcgtcaaacg acttgttttt ccgccgcgaa aatgaatgaa
     2161 ttgtgtatgt tccccttttt cttttgatgc atttatcaaa aaagaagaaa gtagattatt
     2221 tgtgcttgcc aaatgattca atatctctgt agataaggtt tcttctttta ataagatgtt
     2281 gattaaaata tcctcttgcc ctgtgtattc gattctttga gtagcttctt tatcaatgat
     2341 caccacgtca ctttcttcca tctctatcct ttctccatta ataatttgta aacatgtacc
     2401 gctatacata taattgattt caacaaaatc atgtgtatgc tcgggaactt ccgcatatcg
     2461 acggtgttta ctgatatgaa tatttccctg ttgaaataga tcccctcggt ggatttttgg
     2521 cggtgtctga agatggtaag ctaagtttaa atcattgata ttcattcctt gttcacgctg
     2581 cagagtttcg attgattctt cgttacgcaa aaaaaatgtc taattcagct agttccaatt
     2641 gactccctcc tttttgtaag cggtttcttt cgcttattag ttcacgctgt actgctatta
     2701 tatgcaaagc tatttttggt ttcataaaga ctttctatgg ttgggacatg aacttcctgt
     2761 gattccgcta ttgagagaat aaccacttca tactatattt ttgataagcg cttacaaaaa
     2821 tgaaaggaac atgcttatga ataaaaagat gatgaaattt tctctgctgt cagtctctct
     2881 tattttgact tctgctggtg cagtcacgtc tgcaattccc agtatgtcag ctacttatgc
     2941 cacgcgttct ttatctgctg ttgaattatt aacgactgct ccctctttta tggtcactat
     3001 ttttgttttg attagtagtt ttattgctag gaaaatcgga caaaaacaaa ctgtgatcat
     3061 cggattagtg attgcatcga tttgtggtat cctccccctc ttctcacaaa gttacagtat
     3121 tgtcttagct tcaagagctg gactaggtat tggctttgga ttgatcaatt ctttggcagt
     3181 cagcatgatt gctgcctttt atcacggaga tgaacgagcc tctatgattg gttttcaaag
     3241 tgcatttcaa ggatttggtg cagctttaat gacatttgtt gcaggacagc tagtacagtt
     3301 cggttggcaa tatacctttt tagtctacgc catcagctta cctattcttg tcttgtttgt
     3361 tttgtttgtt cctacacctg aaacaactga acttcaatcg catggcacag ccccaacaag
     3421 acaagtaatc aaaacgaatc ctaaaatgat tagttatggt atttttctct tgctggtcat
     3481 cgtggtatat aatgctgtat cgattaaatt agccacagtc ctgacgactt attctctagg
     3541 aaacgaaact aatgcagcga atatcttaac aatcatgcaa ttggcaagta tggctgccgg
     3601 agtttgtttt ggctggcttc agacaaaagc acatcgctat atgcttacac tttctttact
     3661 actgatggga atcggctttg tattgattgc cactgtgata aacctgtatg tgattgggtt
     3721 tggtgcgatc ctaacaggaa tttctttttc gttattcatt ccttacttat tcaaccaagt
     3781 aagtatccaa gcgcccaagt acgcggagag tttcaatact tcaatcttat tggttggcgc
     3841 taatttaggt actttcattg caccatatgg tttgctcttt ctctcttttg cttctcttgg
     3901 gagtaaaaca cttgctgttt tcgtcaatgg cagtatcttg ctgttgatta gcgcgcttat
     3961 tagccttcta gtagtacaca ggacgaatag aaagacagtg ataagagtag atgaagaaat
     4021 aaaagaacaa ttgacaacaa aataaatttg atggaggtcg tgtaaaatga caaatgaaaa
     4081 acataaagat agatggcttt ggtatcctgg agactttgag atccgccatg gactgctaca
     4141 aaatttccaa cgggaagaac gaggttttga ctggccagcg tactggtaca tggatgattg
     4201 ccatcggaac gtcaagttta agagatatta ctttcttgat caaccttcca tgtttaaagt
     4261 gacgatccaa ggagttgggt atgtagaaat taatggacaa aaacatccat gtggaaaatg
     4321 gctgacttgt ccagctggta aagcaaaaat tcgtatcttt gtaggacata catcagggct
     4381 accagcgatg tttatcgagg gagacgaagt aaaatcagat attggctgga cagcaagtaa
     4441 ttttattgaa gaatatccag ctggctggag tccgctttat gtcgatatcg caaaagatcc
     4501 aaatcaaatc tattatcaaa aagaatgcgt ccatccagtc actgaaacgg agattggcgg
     4561 aggaatctta ttcgattttg ggcgagcagt gaatggctgt gtagaactaa tatctctgga
     4621 tgaccatatc gaatctatca ctctatgtta tggagagtcc gatgtagaag ctatggatat
     4681 cgattattgc tactataagc aaataggaat gacaagaaaa atgaaagctc gtaaacgcgc
     4741 ttttcgctat ttgtttatac cagaggtttc tactggaatg gttcaacttc aagtttttca
     4801 tgaattttta tctctttcga aacaagctgc tttttcaagc gattcttctt tactgaatca
     4861 gatctggtca gtatcagaag aagccttcaa gttatgtagt gatttgtttt ttatcgacgg
     4921 tatcaaacga gatcgctgga tttggtctgg agatgcgtat caatcattca tgatcaatca
     4981 atatcttttt tttgacgagg aaatcaataa acgaacgata ttagcattaa gaggacaaaa
     5041 tgaaatcaag cagcatatga atactatcgt tgactattcg atcttgtggt tgattggtat
     5101 cgaaaaccac tatatgatga cgaaagacta tgaattttta cgcatcgtct accctaagat
     5161 gcaatcatta atgagatact tgatggagca aacgaatgaa ttagggttta tttatgggag
     5221 agcaaaagat tggatattta ttgattggtc tgaaatggat aaagaaggaa cgcttgctgc
     5281 agaacaagtc ttattactga aagcctatca ttccatgatc acttgcggag atatcttagc
     5341 tgaaacatat ggagagaacg aaaattatca tactcatctc tatcaagaaa aatatcaact
     5401 attgaaacaa aacctatttg actacttttg ggatgaagaa cttggcgctt ttatcgattg
     5461 ctatgaatct gggagaagaa atgtgacgcg tcatgcgaat attttcgctg ttttattcga
     5521 ttttgctaac aaagaccaac agcaatcgat cttaaagaat gtcttattga atgacactat
     5581 cacacagatt actactccat atttcaaatt ctatgaacaa gatgctttat gcaaactcgg
     5641 acagacgaat atcgtctacc aaacgattct tgattattgg ggagggatgt tatctcatga
     5701 tgcggtaact ttctgggaag aatacgaccc tactcaaaca ggaaatgaaa agtacagtat
     5761 gtatggagat ccttatggaa aaagcttatg ccatgcatgg ggagcaagcc caatctatct
     5821 tttaggacgc tattttatcg gtttgtatcc aacaaagcca ggttatgaag aatttatgat
     5881 acaacctaat ctagattcat ttgaaacact gaattgtacg ctacctatca aagatggaaa
     5941 gatttcgctt gaaaaaacaa aagataagat cgtgattact tctgatagaa caggcggaac
     6001 agtgaaaatg aatggtaaaa gttatcctct tctagcaaaa cagccacttg tcttaacaag
     6061 ctattcaaaa ataaatgcat aaaacaaaaa actgcttgcg acatatcaga agactttaaa
     6121 tcttcttctg atattgtcca agcaattttt attttgaagt ttgcttaatt ctgttcttta
     6181 gaaacaatgt ttgttctttt tccggcaaaa agaaagctag ataatacgac aagtaaaaag
     6241 aaagcgatga ttccaactgt caaggctatt tgaccgtatt ctcctagttt cccaagtaca
     6301 agtcctggta ctagataatc agtatcggca aatgtagaag aagcgatttt aagatctcct
     6361 aatactggaa ggataaataa tggcagccaa ctaatcaata agctattgaa agcagaacct
     6421 aataccgccc ctcttctacc gccagtcgag ttgccgaaga caccagaagc agctccgcag
     6481 aagaaatgtc ctactacccc aggaatgata actgtagttt gcaagcctat catagcaaac
     6541 atggatagtg ttcctacaaa gaagctaaca aaaaagccaa ttaatacagc attaggtgca
     6601 tatggaaaaa cgataggaac atctaatgct ggtttagaat cgggtacgag ttttttagca
     6661 atcccttgga atgctggaac gatttctgcc aacaccattc gaaccccttg aaggacgata
     6721 acaaacccag ctgtgaatgt tccagcttgg atcagtgcaa agattacagc gttgtctcca
     6781 ttgcttagtt ctctttcaac aaatccagga ccagctaaca aagcaagtgc gacatatacg
     6841 atcgacatca agagcatgat cgatacagta gaatctcgca aaaagctgaa acttttagga
     6901 atctttatgt cctctgtaga acggtctttg tttccaaaaa actttccgat ccatccacta
     6961 gaagcataac cgatatttcc ggtatgccct aacgcaactt gattgtttcc agtgatgttc
     7021 ttcataaacg gttgacaaag agcaggcgta atagttaata gtgttccttc gaagaccccg
     7081 cctaataaga tcatccacaa atttgcagta aaccccgcgc ttactaaaat gactgctgtt
     7141 agacaagaaa cataaagcat tgcttgacct gtaagaaaaa tgaatttata tcttgtgaat
     7201 ctagcaagta aaatattcac gatcatccct actagcatga tcaaagcagt aggtgtaccg
     7261 tattgttgca aagcaatcgc cactactgct tcattgctag gaactactcc ttgagtatgc
     7321 agagctgttt ggaacatcga agcaaaaggg gttagtgaat tactgattaa accagcaccg
     7381 ccgatcagta ctaggaatcc gacaaatgtt ttgatagttc cttggatcac ttctgaaaat
     7441 ttcttcttct gaagaacgag accaagcagt gcaatcaaag aaacgaggat ggagggctga
     7501 ctgacgattg acacaaacaa attcaacaat ttatccattg atagttcctc ccttgaatca
     7561 tttttattct tttgacaaga tcttcgttac tttttctttt act
//
LOCUS       DAXLPY010000098         7600 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.099, whole genome shotgun sequence.
ACCESSION   DAXLPY010000098 DAXLPY010000000
VERSION     DAXLPY010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.099"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(138..428)
                     /locus_tag="ACF3UF_002468"
     CDS             complement(138..428)
                     /locus_tag="ACF3UF_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672533.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(546..806)
                     /locus_tag="ACF3UF_002469"
     CDS             complement(546..806)
                     /locus_tag="ACF3UF_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672534.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(943..1356)
                     /locus_tag="ACF3UF_002470"
     CDS             complement(943..1356)
                     /locus_tag="ACF3UF_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFD3672535.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="ACF3UF_002471"
     CDS             complement(1812..2297)
                     /locus_tag="ACF3UF_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672536.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="ACF3UF_002472"
     CDS             complement(2436..2651)
                     /locus_tag="ACF3UF_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFD3672537.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="ACF3UF_002473"
     CDS             2875..3675
                     /locus_tag="ACF3UF_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3672538.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="ACF3UF_002474"
     CDS             3694..5562
                     /locus_tag="ACF3UF_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFD3672539.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="ACF3UF_002475"
     CDS             5555..6046
                     /locus_tag="ACF3UF_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFD3672540.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /locus_tag="ACF3UF_002476"
     CDS             6034..6588
                     /locus_tag="ACF3UF_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFD3672541.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="ACF3UF_002477"
     CDS             6606..>7600
                     /locus_tag="ACF3UF_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFD3672542.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DAXLPY010000099         7426 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.100, whole genome shotgun sequence.
ACCESSION   DAXLPY010000099 DAXLPY010000000
VERSION     DAXLPY010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.100"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            256..1044
                     /locus_tag="ACF3UF_002478"
     CDS             256..1044
                     /locus_tag="ACF3UF_002478"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672543.1"
                     /translation="MEKINESKVSVCKEKGESYFLETLSLKQQEDKLFSEWEKEECLK
                     GYYGINQDGLADESSYLQSLPKIAFILKEAYGKENFDMRPYYYDGAHAGSKTWRTAPL
                     WIAGISKIYEENKSTIAQIKTEKRNMGWKEFNQEYIRKVAILNLNKQCTTNGKLTDRK
                     YFQSGIDNKKFINKQIEIYNPEIIICGGTFYPFYDRIYDYKNFDTKYESANQNKQYAE
                     GYKDKKGRLIINTFHPGAIKKEEPWYDSIMEIVERFKSEGLFAK"
     gene            complement(1130..1234)
                     /locus_tag="ACF3UF_002479"
                     /pseudo
     CDS             complement(1130..1234)
                     /locus_tag="ACF3UF_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1575..2039)
                     /locus_tag="ACF3UF_002480"
     CDS             complement(1575..2039)
                     /locus_tag="ACF3UF_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672544.1"
                     /translation="MPRINRKKPTGDFESVFDEELEELETPNDTIDSIPETEVTVSNS
                     FPSDKETITENFNEANRFGLSKTSKSTSSELVARTFKYKKETIQRVESLVYKDQRHSK
                     KIPGTKGFISDFMDNAIWQHLLQLGLATEEEVQKHLNSYSKYPLNFDNYEKK"
     gene            complement(2039..3004)
                     /locus_tag="ACF3UF_002481"
     CDS             complement(2039..3004)
                     /locus_tag="ACF3UF_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3672545.1"
                     /translation="MAVVLTVAANKGGVGKTLITINLAGAIRRSFPEAKILVVDTDAQ
                     GNSTKSFRVKVAKDQNTIYDVFMDNATVEETIVQTYDDHIDVLPANSDNNYLEFDKME
                     QFRDTILEWFVSLLKKFKDNLTEIMTVSGLKKKMNNIIDPSANYFNALDGKFDNVSDK
                     YDYIIFDTPPELKQVTSSVLSIADVVIVPYEPDLNGVDGVTHLISRVNTLKEKYNPNL
                     RIGGVLANKVYNTNLHAKMINAMMKYTNRNNYHYFDSELPRSITFADKLVRNGMPITM
                     SSPENKFAQHFYKLIIEMNKLGLLSKNGKELEIPHKLYVESDGEE"
     gene            3391..3717
                     /locus_tag="ACF3UF_002482"
     CDS             3391..3717
                     /locus_tag="ACF3UF_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFD3672546.1"
                     /translation="MKKNSKEFRNEYDRFVLKFLIDNYYISRIDLSKAIGLAPSYVRE
                     FYNGSRSFGNEALEKLESTIFNLYKPLLENHSFELNQVQEMIESIDSEEELELFRLKG
                     ANVLDI"
     gene            4102..5595
                     /locus_tag="ACF3UF_002483"
     CDS             4102..5595
                     /locus_tag="ACF3UF_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFD3672547.1"
                     /translation="MTASLDVVYSTILQNGIRKFKYKNSRLKPVSFSEQTGKGAIFAY
                     RSKEHMVEGIGLVITSEEGIIENNNAFSHWTPNVFRYGTYTDEGRMFTKGHSEDNLRQ
                     INTFFVDFDTLDPNFDYGEILLASHELGFMPTMVLRTPHGYQAFYVLDQPAFVTKKSN
                     FKVINVAKMISNNLRKTLAKDFPVDVNANHFGITRMPNEDNTLFFEPQYRYSFADWIN
                     WSMRVDADKAVTYRNVFELPSNQDFRQVDEPWFRLLMRSEKIKGEKGRYGRNNVIFTL
                     SLAYFSSGYEIEECELAMLEFNDRLAYPLTDRELTRIIRSAYSGKYQAAHREKIILLC
                     QEWIDENLSEEQLFNKKKGWWKFKKERKVRKYSHSHEWAQDLLAYLNQQSYTYKPYIV
                     STKKELREELKIPERSLDKVLKQLKNENKIYYRVRSGRNGGITLASVHGLMRSIIRVK
                     KEVQEAYFSAISEVFGLARTFIYSTLEQLIEAPKKAEQMELFEVDTG"
     gene            5753..6037
                     /locus_tag="ACF3UF_002484"
     CDS             5753..6037
                     /locus_tag="ACF3UF_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFD3672548.1"
                     /translation="MGVNTFVYPYPVSVFIIQRLGMTVEEFCELHGYRQSTVATWAYR
                     NRPVKVLPCDFLYCLSLASGLSMDKVYQDLLLLEEKFLQSLDPKKEKKSI"
     gene            6073..6198
                     /locus_tag="ACF3UF_002485"
     CDS             6073..6198
                     /locus_tag="ACF3UF_002485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672549.1"
                     /translation="MFRVEIVEKKTIEKLEKAVNNILISKGDKVQTIEYAAVKKI"
     gene            complement(6425..7105)
                     /locus_tag="ACF3UF_002486"
     CDS             complement(6425..7105)
                     /locus_tag="ACF3UF_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFD3672550.1"
                     /translation="MNHFKGKQFQKDVIIVAVGYYLRYNLSYRDVQEILYNRGINVSH
                     TTVYRWVQEYGKLLYNIWKRKNKQSIYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPRVLVTDKAPSIASAFKKLQAHGFYQRTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYRSLRTASTTIKGMEAIRGLYKKNRKEGTLFGFSVCTEM
                     KILLGIPA"
     gene            7291..>7426
                     /locus_tag="ACF3UF_002487"
     CDS             7291..>7426
                     /locus_tag="ACF3UF_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
                     /protein_id="HFD3672551.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     F"
BASE COUNT         2468 a         1163 c         1397 g         2398 t
ORIGIN      
        1 ctcctggtat gttttcttct agtctacaca ccttaatttt tctgtctagt taattgtagc
       61 ctatccagag tataatcatt gtaaggtcaa gtatttgact ttttcgatta tgagagcgtt
      121 accttttcta ttactgaagc ctttataaaa tggcgaaata atagaagaaa ctgaaagctc
      181 ttaataaata gacaaactac gttccaatag acgttttaaa aagggtatga aatacagcat
      241 acaaggagtg aaaaaatgga aaaaataaat gaaagtaaag tatcggtctg caaagaaaaa
      301 ggtgagtctt attttttaga aacgttatcg ttaaaacagc aagaagataa gctgttttct
      361 gaatgggaaa aggaagagtg cttgaagggg tattatggga taaatcaaga tggactggca
      421 gatgaaagta gctatttaca atcacttccg aaaattgctt tcatcttaaa ggaagcatac
      481 gggaaagaaa attttgatat gcgcccttat tattacgatg gtgctcatgc tggaagcaaa
      541 acttggcgaa ccgccccttt atggattgct gggatatcta aaatttacga agaaaataaa
      601 agcactatag ctcaaataaa aactgaaaaa agaaatatgg gttggaaaga gttcaatcaa
      661 gaatatatac gaaaggtagc tatcctaaac ctcaacaaac aatgtacgac taatggaaag
      721 ttaacggatc ggaaatattt tcaatccggt atagataata aaaaatttat aaataaacaa
      781 atagagatat acaatccaga aattattatt tgtggaggaa ccttctatcc gttttatgat
      841 cgtatttatg attataaaaa ctttgatacc aaatatgaaa gtgccaacca aaataaacag
      901 tacgcagaag gatataagga taaaaaaggc cgattgatta taaatacttt ccatcctgga
      961 gccataaaaa aagaagagcc atggtatgac tctataatgg aaatagttga aagattcaaa
     1021 agcgaaggct tgtttgctaa gtaagtgagt tccttcttcc aaattacaaa aaataatgga
     1081 taggctacac accttaattt ttctgtctag ttaattgtag cctatccagt cgcgcacgtc
     1141 ctaagcattg cgcagttttg gtaacggatt gattattttt gaaataagac tctatgacta
     1201 ctagttcgtc tgttgtaaga tgggtgtagg tcatttgtac tcactcctta ataattcttt
     1261 ggtcggaact attttgagtg tagcacaaat gatcttttta gttgtctagc ttaattttac
     1321 aatcgacgtt gtaaaaatta tatatgatta tgtaaaaaag aataaaataa ctaaaaaatt
     1381 taactgataa aaaaattgta atgacaaaag aacggatctt ttatagatcc gctctttttg
     1441 atgagatagt aatatttaaa gtaatataaa tagtaatatt atggtaatac acatagtaat
     1501 atatatcgta atattgtggt aatacaaata gtgatataaa aatttcgccc tataaaaaaa
     1561 gaaatagcga taagctactt cttttcataa ttatcgaagt taagtggata cttactatag
     1621 ctgtttagat gtttttgaac ttcttcttca gtggcaagtc ccagctgtaa taaatgttgc
     1681 caaattgcat tgtccataaa atctgaaata aatcccttag tcccaggaat ttttttagaa
     1741 tgtctttggt ctttgtacac taaactttca actcgctgta tagtttcttt tttatattta
     1801 aatgtacgtg caactagttc agaacttgta gatttcgaag ttttgcttaa gccaaatctg
     1861 tttgcttcat taaagttttc ggtaattgtt tctttatctg agggaaaact attgctaaca
     1921 gttacctcag tctcaggtat gctatcgata gtgtcattag gtgtttctag ttcttccagc
     1981 tcctcatcga atacagactc aaaatctcct gttggttttt ttctgtttat tcttggcatt
     2041 attcttcacc gtcactttca acatataact tatgaggaat ttctagttct ttaccatttt
     2101 tagaaagtaa acctaacttg ttcatttcga taatcagctt ataaaaatgc tgagcaaatt
     2161 tgttttcagg tgaactcatt gttatcggca ttccgtttcg aactaattta tcagcaaagg
     2221 taattgatct tgggagttca gaatcaaaat aatgataatt gtttctatta gtatatttca
     2281 tcattgcgtt aatcattttt gcatgtagat ttgtattata gactttgttg gcaagtacgc
     2341 ctccaatgcg taaatttgga ttgtattttt ctttcaatgt gttcacacga gatattaagt
     2401 gtgtaactcc atcaacccca tttaaatcag gttcataagg gacgataact acgtctgcaa
     2461 ttgaaagaac agatgaggta acttgtttta actctggtgg tgtatcgaaa atgatgtaat
     2521 cgtatttatc actcacatta tcaaatttac catcaagagc attaaaatag ttcgcgctgg
     2581 gatcaataat attattcatt tttttcttta atcctgaaac agtcatgatt tcagttaagt
     2641 tatccttaaa ttttttaagt aaagatacaa accattctaa tatggtatca cgaaattgtt
     2701 ccattttatc aaactctaaa tagttgttat cagaattcgc aggaagaacg tctatatgat
     2761 cgtcatatgt ttgaacaata gtttcttcaa ctgttgcatt atccatgaag acatcataaa
     2821 tcgtattttg atccttagct actttcacac gaaaagactt tgtactattt ccttgagcgt
     2881 cagtatcaac gacaagaatt tttgcttcag gaaaactcct acggatagct cctgcgagat
     2941 tgattgtaat aagagtttta ccaacaccac ccttgtttgc tgcaacagtc aaaactactg
     3001 ccatttttca attcctccct aaataatata atagtaatat ttttggtaat agataagtaa
     3061 tatagataat aatatataaa gtaatatttt gttaatcgta acaatacgag aaagtaatat
     3121 actatattac tttctcatat tagcataata cgttgtcgaa atcaacaata aatcaaaaaa
     3181 taaaacagca gattttatat tatgttacta ttgataatag taacataata gtaagataat
     3241 atattatatt actattatgt taccttttaa acactgatag atagggaatt tgaagaatta
     3301 tattaaaaaa aggattgtat ataaattttt ttgatggtaa tattataaac gaggatgttg
     3361 ctataattaa caacgaagag gtaagatttc atgaaaaaaa actctaaaga gtttagaaac
     3421 gaatatgaca gattcgttct taagtttttg attgataatt attatataag ccgaattgat
     3481 ctatctaaag ctattggatt agctcctagt tatgtgcgag aattttataa tggatctcgt
     3541 agctttggaa atgaggcatt agaaaaacta gaatcaacaa tttttaactt atataaacct
     3601 ttgctagaga atcattcatt tgaattaaat caagtacagg aaatgataga atcaattgat
     3661 tctgaagagg aacttgagtt gttcagactt aagggagcta acgtattaga catttagata
     3721 atttctactt gatttggtaa attatattta caactttcaa cagattcggt aagataaaaa
     3781 aaatatataa aaaagagacg gataaacaag tgaattggac ctcactcatt tatctgaatc
     3841 acataaagca actatgtgtt ctcgctcgtc tcaaggaaat tatgtaagtg gtagccaacc
     3901 acttatgtga tttgaataaa tctgttcgga ctaccaatcc gaacctgtag gtttatttta
     3961 ccatttttag acgggcaact caatagataa acgcttattt gtcatgcttt ctttagattg
     4021 ttttgatatt tctagcgatt gagagaacac agatcgaacg attatttgtg ttctcttttt
     4081 gtttagaaag gataagtagg catgacagct tctttagacg tcgtttattc aacgatctta
     4141 caaaatggta tccgtaaatt taaatataaa aatagccgcc ttaaaccggt ctcttttagc
     4201 gaacagacgg ggaaaggggc tatttttgcg taccgttcaa aagagcatat ggttgaggga
     4261 ataggcttag tgatcacgtc tgaagagggc attatcgaga ataacaatgc gtttagtcac
     4321 tggaccccaa acgtcttccg ctatggcacg tatactgatg aaggcagaat gtttacaaaa
     4381 gggcattctg aggacaattt acggcaaatc aacactttct ttgttgattt tgacacctta
     4441 gacccaaatt ttgattatgg agagattttg ttggcaagcc atgagctagg atttatgcca
     4501 acaatggttt tgcggactcc ccatggttac caagcgtttt atgtactgga tcagccagct
     4561 tttgtgacaa agaaatccaa ttttaaagtg atcaatgtgg ccaaaatgat ttctaacaac
     4621 ttgcgaaaga cattagccaa agattttcct gtagacgtca atgccaatca ttttggaatc
     4681 actcgtatgc caaatgaaga caatacctta ttctttgagc cccaatatcg ttatagcttt
     4741 gcggactgga tcaactggtc aatgcgtgtc gatgcggata aagcagtaac ctacagaaac
     4801 gtttttgaat taccgtcaaa tcaggatttt cgccaagtgg acgaaccctg gttccgtcta
     4861 ttgatgcgta gtgaaaagat taagggagag aagggaagat atggtcgaaa taacgtcata
     4921 tttaccctgt ctttagcata cttttcttcc ggatacgaaa tcgaagagtg cgagttggcc
     4981 atgttagagt tcaacgatcg attagcctat cctcttactg atcgggaact gacacgaatt
     5041 atccgatcgg cttattcagg aaagtaccag gcagcgcaca gagaaaaaat tattctatta
     5101 tgccaggaat ggatcgatga aaatttatct gaagaacagc tgtttaataa gaaaaaaggc
     5161 tggtggaaat tcaaaaaaga gcgtaaagtg cgcaagtatt cgcacagcca tgagtgggcg
     5221 caagatctct tagcttattt gaaccaacaa tcatacactt ataaacctta tatcgtttca
     5281 accaagaaag agttaagaga agagcttaaa attcctgaac gctccttgga taaagtattg
     5341 aaacagctga aaaatgaaaa taagatctac tatcgtgttc gttccggtcg caatgggggg
     5401 ataactttgg cgtcagtgca tggcttgatg cgatcgatca ttcgagtgaa gaaggaagtc
     5461 caagaggcgt attttagtgc tatttcagag gtttttggat tggcacgtac atttatctac
     5521 tcaacgctgg aacaactcat agaggcacct aaaaaggctg aacaaatgga attgtttgaa
     5581 gtggataccg gataaaaata aaacccgcaa attgcctttt acattatatc tttgatacgc
     5641 tctccgagtc agaggtttta caggtcttag ggaattccct tgattgcaat gtttggataa
     5701 gtgaggtact attatcgcat atgtgattat atttcttagg gggttaccgt ccatgggagt
     5761 gaatactttt gtttatcctt atcccgtcag tgttttcatt atccagcgtt taggtatgac
     5821 tgtggaggaa ttttgtgagt tacatggtta taggcaaagt accgtagcaa cttgggctta
     5881 tcggaatagg cctgtaaaag tcttaccctg tgattttctg tattgtttga gcttggcttc
     5941 tggtttgtca atggataagg tttatcagga tttattactg ttggaggaga aatttttaca
     6001 aagtttggat cctaaaaagg agaaaaaatc gatttaaagt ttagtaagtt tgaaaggaag
     6061 agggggataa taatgtttcg tgtagaaatt gttgaaaaga aaacgattga aaaattggaa
     6121 aaagcagtga ataatattct tattagtaaa ggggataaag tacagactat agaatatgct
     6181 gcagtaaaaa agatttaaac gtctattatt ctgctatgat tgtatataag gcttgaggat
     6241 gttttgagtt gttaggaatc taagggaagt aaaaatattt ctataggaga acagaaaaga
     6301 tggataatga tcattgtgag aatgtaaaca agttagaaag tgcgggtaaa acttattata
     6361 ttattggtgc ggttctgttg caaagttcca aaatgaacaa tactagtcta acactagcta
     6421 tagtttatgc aggtattcct aataatatct tcatttccgt gcagactgaa aacccgaaga
     6481 gagtgccttc ttttcggttc ttcttatata atcctcgaat ggcttccatg cctttaatcg
     6541 tggttgaggc tgttcgtaag cttcgataaa atttgtttcg tctcttgatg ggacgatgat
     6601 cttgttcaat gaggttattt agatatttca ccgtgcgatg ttctgttcgc tggtaaaacc
     6661 cgtgtgcctg taattttttg aaggcactgg caatagaggg agctttatcg gtcaccagaa
     6721 cccttggttc atcgaactgt ttaactaatc tcttgagaaa ggcgtaagct gcttgtgtat
     6781 ctcgcttttt ccgtaaccat atatccagag tgagaccatc tgcatcaatg gcgcgataaa
     6841 gataatgcca ttttcctttg attttaatat aggtctcgtc cattttccac gaataaatgg
     6901 actgtttgtt tttcctcttc caaatgttgt aaagtagttt cccatattcc tgtacccaac
     6961 gatagacagt ggtgtgagac acgttaatac cacggttgta cagaatttct tggacgtcac
     7021 gataactcag gttgtaccga agatagtagc ctacagcgac aataatcaca tctttctgaa
     7081 attgtttgcc tttaaaatgg ttcatcttcg ttactcctcc tagttcctat taaactcagt
     7141 ttaccctata atggatctga ggggaaactt tgcaacagaa ccagttgaag aacaaactgg
     7201 aatcaatcgc cgaacgttta gaaggtatcg agcaagatat aacgtgacag tagatcaaag
     7261 aaaaaacaat gaaaagaggg atagttaatg atgagtacgg ttattttagc tgaaaaacca
     7321 agccaggcat tagcctacgc aagtgcttta aaacaaagca ccaaaaaaga cggttatttt
     7381 gagatcaaag acccactatt tacagatgaa acgtttatca cctttg
//
LOCUS       DAXLPY010000100         6904 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.102, whole genome shotgun sequence.
ACCESSION   DAXLPY010000100 DAXLPY010000000
VERSION     DAXLPY010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.102"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..173
                     /locus_tag="ACF3UF_002488"
     CDS             <1..173
                     /locus_tag="ACF3UF_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HFD3672552.1"
                     /translation="RNIFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLF
                     ATLLNYSIYFLN"
     gene            complement(281..1507)
                     /locus_tag="ACF3UF_002489"
     CDS             complement(281..1507)
                     /locus_tag="ACF3UF_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD3672553.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(2261..2461)
                     /locus_tag="ACF3UF_002490"
     CDS             complement(2261..2461)
                     /locus_tag="ACF3UF_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3672554.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(2595..3203)
                     /locus_tag="ACF3UF_002491"
     CDS             complement(2595..3203)
                     /locus_tag="ACF3UF_002491"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFD3672555.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(3288..3758)
                     /locus_tag="ACF3UF_002492"
     CDS             complement(3288..3758)
                     /locus_tag="ACF3UF_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFD3672556.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(3806..4720)
                     /locus_tag="ACF3UF_002493"
     CDS             complement(3806..4720)
                     /locus_tag="ACF3UF_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFD3672557.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            4866..5669
                     /locus_tag="ACF3UF_002494"
     CDS             4866..5669
                     /locus_tag="ACF3UF_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFD3672558.1"
                     /translation="MTTKQLIISSFIRFKDLKETRNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKELR
                     SFLSKASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            5847..6794
                     /locus_tag="ACF3UF_002495"
     CDS             5847..6794
                     /locus_tag="ACF3UF_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFD3672559.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         2149 a         1368 c         1046 g         2341 t
ORIGIN      
        1 taagaaatat tttcattgca gcaatcgata ttacactttt agttattttc ttgtcagtgc
       61 ttatgtatca gttgtggcta catcatcgcc tggcaatgtg gctcatgatt ccttattatt
      121 tatgggtact attcgcaact ctattgaatt attcaattta ttttttaaac taagcgctaa
      181 aaagagacgt cctgtaattt aacacataga aaaagtgcca cctaagttag attttttgtc
      241 taatttaggt ggcactcttt attaaccaaa ctattttttt ctagtaccca cttgttgttc
      301 catactcatt attctggtca taaccataac cattttgttc ctgtccagcg taaggatcat
      361 aactttgagt atcttgactt ggtgtatagt actgacttgt atcttctgtt tgctgataat
      421 aggtattcgg atcttggtac tgatcatatg tgttttctga ataggaagaa taatcggtgt
      481 acccttcact attcgatcca tcaccgtttg tcgaatcgcc atcttccgaa tcatcaaaga
      541 acatcattga agcattctca tttttcaaat taggtaatgt atcgcttgtt tttatattta
      601 attgtttctt cagttcattt tggatcgaaa gaagatcatt ttttcctaaa atttgatagt
      661 agatatcatt gatcatttgt ccttcgcctt gcaactggtc ttgtttgatt gtttcaaacg
      721 caggggtgta gttcgtcgct acatcaagca tgtcatccca atctaagtcc gtcgtcacat
      781 tgttctcaac tgcttttaaa atttttctat aattgcttac gccatctaaa cttaaaactt
      841 tattgacgat tttcgtcact acttcccgct gacgacgttg tcgaccgata tcgccttctg
      901 gatcttcgtg tcgcattcga gaataggcta aacctttttc tccattcaat gtttgttcac
      961 ctactggtac atggacacca tccaaagtaa agtcaatttt attattcact ttgatgccac
     1021 cgaccgcatt gatcaaatct tccatgccat ccaaattgat cgttacataa tgatcaatag
     1081 gaatatcgag cagttgctca attgaatcca tggccatttc gacaccacca aatgcatagg
     1141 catgatttaa tttatctacc gttccataac ctacgatatt cgtataaata tctcggtcca
     1201 aactgatgat cgttgatttt ttttgtttcg gattaactgt tactaccatc atcgtatcag
     1261 aacgtccttg ttccgttctt cctaatccac cggtatctaa acctaatagc aaaaccgaaa
     1321 aaggttcttt gtcatcaatg cttactctct cagaacgttt ggaggatatt cgattagagt
     1381 ttttagaaat tttgtttact gtttggctcg cttctcccat aaatctgatt ccgtatgctg
     1441 ataatccggc aatcagcaaa acaaataccc ctaacaaggt taatagaact ttttgccatc
     1501 gcttcataat acacctctgt ttcacatttt ctaaaatatt gtctcatata actgttcaat
     1561 cagcaaattc actttttaat cataagaaaa ctttaaaaaa catttttgtg taacgattac
     1621 tattttttaa aatttctcaa aattcttaac tatcatacca taccgtgaaa aagatcgaaa
     1681 gaccgaatac acgcagttcg caatcgtttt atcttttttt acgtattttt tccagaaaaa
     1741 gcgaacaaca aggtattttc caaataatcg tgcagtaaaa tgatcgcaca tacctttccc
     1801 atctttttaa cagtctttgc ctaccgttca gattatcatt cgatttcacg aaaatttctt
     1861 cctatgactg gtccttttgt taaacccatc ttctattcgt tttatttcca gctcactgca
     1921 tggctcttaa aatgactcga actagtgatt tcattaccat catcttttaa tggatagata
     1981 tgctcctctt caaagtaaaa cgattttctt ttaaagtaat agaattgaca tggtaatgag
     2041 tatgtatact agtggtttca caaatggtct tttattcaac atccaaaaac tgaaatttct
     2101 ttaaaatcca ttactaacga agaaaatgtt ccttgcttga taattagtta ggacatgtca
     2161 agtgaacaaa tgcatttact tagccaaaaa atctaaaaac ttcataaata gacaaaaaga
     2221 cacgactctc taagaagtcg tgtctttatt caacaaatta ttataattta gtcacttcag
     2281 cagcttgagg tccgcgtgca ccttcaacaa tcgtgaattc tacttcttga ccttcttcta
     2341 ggctcttgaa gccgtctcct tgaattgctg agaaatgaac aaatacgtca tctccgccgt
     2401 ctactgtaat aaacccaaat cctttttcat tgttgaacca tttaaccgtt ccgtgttcca
     2461 taaatgtata gcctccaaaa aagttcttgc aagtaacctt gcaagaacat tatacccaat
     2521 ttagaaaacg ctagcaagct ttcgctcttt tattttccaa attattttta agactgatat
     2581 gacggaggaa atggttattt tgctgcttcg aaacgtttgt ttacttcatc ccaattaata
     2641 acattccaga atgctgcaat ataatctggt cggacatttt tatatttcaa ataataagca
     2701 tgttcccaaa cgtccaaacc tagaattggt gtctttcctt ccatcaatgg agaatcttga
     2761 tttgcagtag aggtaatagc taattttcca ttttccatta caagccaagc ccatccagaa
     2821 ccaaatcgtc cagcggctgc ttttttgaat tcttctttaa aagaagaaaa atcaccaaaa
     2881 gcttcattaa tcgcttcttt tatttctcct gtaggttcgc caccagcatt tggtgccatg
     2941 atttcccaga aaaatgaatg gttagcatgt ccgccaccat tgttacgtac agctgtcttg
     3001 atatctgttg gaatagcgtc catatcagat aataattctt ctattgtttt ttcgcctaat
     3061 tctgggtatt tctcaattgc tgcatttaaa ttcgtcacat aagtattgtg atgcttatca
     3121 tgatgcagat gcatcgtttc ttcgtcaata taaggttcca atgcgtcata tgcataaggt
     3181 agatctggta atgtgtaagt cataaaaaaa ttcctcctca atgttttctt tataatgtct
     3241 acattacaaa gagtaacaaa gagaaggaaa ttcttcaatt gttatgccta gtcgtctttt
     3301 tcactttgac ctacttcttc ttcaaaaacc tcagtttctt taaaaataaa caacttgctg
     3361 aaaatatagt tcgctaggat aacaataatt tgagtgatga ttttcgccac atactcattg
     3421 ctgttcataa cattgatcaa caataccatt gcccccatgt ccaatccgta agaaaggata
     3481 cggtagaaga agaacttacc gcattcaata agtgcatgtg taaaattcgg tgattttgaa
     3541 tggaataccc aaagtttgtt cgttacaaaa gcaaacaata cagaacaaaa ccacgaaata
     3601 gaattggata aggccatact taaatcaaaa tattggcgtg cgagagcaaa actaacaaaa
     3661 tttacaatcg tagccaaacc accaaaaaag agatagacta gtatctccca atatcctttt
     3721 gcttctaaat atccttttaa ctgtcgatac tgcttcatga gccaacctac cttattaaaa
     3781 attcttattt atcatactct atatttcaat aactttcatc tttatttaaa aaaattaatt
     3841 ttttttgatc ctttgccttt gtctctgctt ggatcgtcac atgtgtaata ccatatttta
     3901 attttaataa agaaattata cgaggatata tcttttcaat ctcgcttagt agctgatctt
     3961 caaaatcaat atgtccgtcg aaaataatta tcttttcgct atactgccaa atatggacat
     4021 gatgaacatt ctttacccca tcgattgctt caatttcttg ttccattttt tcatagtcaa
     4081 tagcaggtgc actttgtatc aaaatagcgg cagctttttt gatcaccatt atcgcttcta
     4141 tcaatatata tatcgaaatg atcagtgtaa taactggatc gatccagtag atatcgaaaa
     4201 aacggatcaa aattgctccg ataatcacac ttaccgaaga cagtgtatca cttaacaaat
     4261 gcaaataact agattttata ttcaaacttt catctgcttc ttgtcgtaat aataatactg
     4321 agaacaaatt cgcgagcaat ccaataactg ctactgttag catcaaatga ctatttatct
     4381 tttctggtga agtgaaccgc ttgaatgctt caacggttaa aaacaaggat aatatgatca
     4441 atatgaatga gttgatgaaa gcactcaata tttctaaacg ctggtagcca tacgtacgtt
     4501 ttttatttgc ttcttttcgg gccatttttt gtgccccgta agaaaaaata attgccaatg
     4561 tatcactaag gttatggaaa gcatctgaaa caagagacaa actccctgac ataatccctc
     4621 caataaattc tgataaagtg atcaccgcat tcaaaaccac tactccaaat agtttttttg
     4681 atgatctctg tggctgtgta ggcactattc cttcctccat tttatttata ttggatagtc
     4741 tttagacaag aataacattt ttttgatatt tcaccaatca ttcagatgtt tccctaaagc
     4801 acttgtattt cacttgatac ttcgctagaa ttgcaagtga tgacactact agatgaggag
     4861 tacttatgac aacaaaacaa ttaattatca gttcctttat acgattcaaa gacctaaagg
     4921 agacgagaaa tgtcccattt tggaaagcca ttgtctatct tttagttttg agtataatta
     4981 tggctttgcc aatctctttt caagtttttc aagtcttaaa caacattcaa ttggatgggc
     5041 aaaagattgc tactcgcatt cctgatttta caatccaaaa cgggcagctt caaaccgaag
     5101 aaaaagaagg attcatttac caaacaaact ccattatctt cacatttgat ccagagggaa
     5161 aacgaacaga acaggacatc tctactgatt tgatggggaa ttttgttagt gtcgggatgt
     5221 taaaaaacaa acttatcata gctcttccta atacaggcac gacttctgct ttgttgaaca
     5281 ataaccaatt agaacttccc tacaccaatg aatctttaaa aaacttaaca ggtaaggagc
     5341 tccgttcttt tttaagtaaa gcatctatac cactttggat aaaagtcctg acatttatat
     5401 tttctattta tcctagtttt ctgaatctgc tgatcacttt gctatttacc aacattgctg
     5461 cttttctcta tgcacgcttt cgactaacaa aagctacttt tcttgattgt ttaaaaacat
     5521 tgatctattc aatttcattg cctactataa ttgcaacaat cttgatggtc tttcttcctt
     5581 cttttgacac aagcgccttc attgcttttg caggaatctt tatttttgct caagctgtca
     5641 aaggatgggc aaaaatatcg atcaattaag aaataaagac aactcgttat ttctacttca
     5701 atagaccctt ttagaggttg tgacattttt ttgtcacagc ccctttttta tttgaaaaat
     5761 atttctttct caaaaaacaa gcaaggcgct tcaaagttct tcttgtatgc gctacactta
     5821 gagtaaagaa aggcgggaaa ttaactatgt cagaaagaat catttatgca gatcgtccat
     5881 ttcgtgatga atttatcgaa gaaatccata ctatagcgcc tggttatatc tttaaaacag
     5941 aattacaacc agaggatcta caaaatgtag agatcagttt gggctggaac tcagactacc
     6001 aagaaaaact attagcctct tctaccttga aatgggtcca atctatctca gctggtgttg
     6061 atcagctacc ccttgagact ttttcaaaga aacatatttt actttcaaat ggtagtggca
     6121 tccacagtga atcgattacg gagcatgtct taggaatcat ccttgggtat tctcgtggtc
     6181 tttttcaagc acaaaaagca cagagtgaca tgaaatggtt aggttcatcg gtccattacc
     6241 aatctatcca aggaaaaaaa atactaatca ttggaactgg ccatattgga aaaatgattg
     6301 caaaaaaatg caaagcatta gacatgaact gctatggaat caatacatcc ggtcatccag
     6361 cagaaggaat ggaaaagact ttttctttaa atcaactaaa ggaagttctt cctgaagtag
     6421 atttcgtagt caatatctta cctctaacgg aggaaacaac tgggctcttt gatcagcata
     6481 tgtttgaaca ctttgatcca aaatctgtat tcatcaatgt tggccgtggt gcttctgtta
     6541 agacacaaga tctggtgcag gctttaaata accagcaact ttcctttgca gcattagacg
     6601 tttttgagga agagcctctt ccacaagatc atcctctttg gaaaatggac aatgtactga
     6661 ttacttccca cattgcaggt ttgacacctg attttcaaaa gaaattaatg gctatttttt
     6721 taaccaatct gaaaagctac tttgccaccc atgagcttca aaccaatcaa gtaaaattgt
     6781 ctgcaggata ttaatagctg aaaacaatat tttcaaaaga acaaagagaa ggtgacaaaa
     6841 ctggctctat aatttatggg actgatgaat cagaattgat tcttcagccc catttttatt
     6901 ttag
//
LOCUS       DAXLPY010000101         6874 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.103, whole genome shotgun sequence.
ACCESSION   DAXLPY010000101 DAXLPY010000000
VERSION     DAXLPY010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.103"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..182)
                     /locus_tag="ACF3UF_002496"
     CDS             complement(<1..182)
                     /locus_tag="ACF3UF_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3672560.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="ACF3UF_002497"
     CDS             517..951
                     /locus_tag="ACF3UF_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3672561.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="ACF3UF_002498"
     CDS             974..1294
                     /locus_tag="ACF3UF_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672562.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="ACF3UF_002499"
     CDS             1435..1626
                     /locus_tag="ACF3UF_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672563.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="ACF3UF_002500"
     CDS             complement(1697..1954)
                     /locus_tag="ACF3UF_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFD3672564.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="ACF3UF_002501"
     CDS             2112..2375
                     /locus_tag="ACF3UF_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672565.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="ACF3UF_002502"
     CDS             2399..2587
                     /locus_tag="ACF3UF_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672566.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="ACF3UF_002503"
     CDS             complement(2670..2855)
                     /locus_tag="ACF3UF_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672567.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="ACF3UF_002504"
     CDS             3070..3441
                     /locus_tag="ACF3UF_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3672568.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="ACF3UF_002505"
     tRNA            complement(3591..3663)
                     /locus_tag="ACF3UF_002505"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="ACF3UF_002506"
     CDS             complement(3709..4137)
                     /locus_tag="ACF3UF_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672569.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4955)
                     /locus_tag="ACF3UF_002507"
     CDS             complement(4197..4955)
                     /locus_tag="ACF3UF_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFD3672570.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            5250..5447
                     /locus_tag="ACF3UF_002508"
     CDS             5250..5447
                     /locus_tag="ACF3UF_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672571.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            5553..6035
                     /locus_tag="ACF3UF_002509"
     CDS             5553..6035
                     /locus_tag="ACF3UF_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672572.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(6093..6689)
                     /locus_tag="ACF3UF_002510"
     CDS             complement(6093..6689)
                     /locus_tag="ACF3UF_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFD3672573.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
BASE COUNT         2328 a         1059 c         1351 g         2136 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccct
     4921 agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt tcagctgttt
     4981 atctttccta ttataaatgt atttttattg gaaatggaag tattatattt taatatgtag
     5041 gaaataatta gtttttaagg aatatgtttt aattttttga aaaaaattct tctaaataca
     5101 acagctgttt taattgtgaa aacgaaaaca gtacgctata atgcctgtaa ggttgatttt
     5161 taactgtaaa taaaaatcaa tgagttaaat ctccaaagaa atagcagtgg taatgtggag
     5221 aaaagttcca gcagtttagg aggattttga tgacggaaga aatgattaat ttaggagaac
     5281 aatatgcatg caaaccaatt ggttttacaa aaacggtcat tggtgaagtt gtatcaaaaa
     5341 tgacaaactg cgccgtggtc aaagttgccc aatgtgctgc agaggaccaa gaattattag
     5401 atgaaaaagc aagcatggtt gttgcaaaat atgatacatt tgaataaaga aaacaattgg
     5461 acgtgcggcg tgctgcaagt ccaatttctt tgagaaggta aatcagtatt cttttcctat
     5521 tttctggaga agaaaaagcg aggcgagttg tcatggtaac attctttacg gttctattgt
     5581 ttttattcgt tgttgtgatg tttttatttc tttggctggt tcgaaaagaa attatttatc
     5641 ggactgtgcg aaatcgatgg gtctacttgg tgataccctt cttagtgtca ctagtcattt
     5701 ggtatacact catcagtcat cctacagcag atgaattggc aaaagggatc ttgtcagcaa
     5761 tgatttttat tagttttttg ttggacagta gaggaatcac agaagaagga cttgttttga
     5821 atagctttga caaaaaaggt gttccttttt ctgagatcaa taaaattgta ttatatcagc
     5881 caaaaggttc taaaatcgta aaaatgaatt ttttccgaaa cggatggcga ggaccgatgc
     5941 tgaaattttc tgcatcatta gaagaattag ttccattttt gtcccaacgc ttaaacgatg
     6001 aggcagagat tgatattatg attgatccag aataaaaaca gaggttgcga caagatgttt
     6061 gtcacaacct ctgtttttta tttcaaataa aattatccaa atacgcggaa gcgatcggca
     6121 tcgttcatgt attctttttc cccagccggt gtttctggtg aaccgaatac taattgcgaa
     6181 cgtagtttcc agtttgaagg gatattccat tcttttgcaa ctgcttcgtc aataactggg
     6241 ttgtaatgtt gcaagtttgc gcccaatcct ttatcaacta atgctaccca agtattagct
     6301 gttgcgattc cgtttgattg ttctgaccaa tctgggaagt tgtctgcata taattcaaat
     6361 tgttcttgta gaccttttac cacgtcagta tctttgaaga ataatactgt accataacca
     6421 tttttgaaac cagctaattt gttttgtgta tttgggaaag cttctgctgg agtcaatggg
     6481 cgaagtgctt cttcagtgat ttcccaaagt ttttcatgtg catctccgaa aaggataact
     6541 gcgcgtgttg attgagcatt gaaagcagtt gggctttctt taattgcttc tttgatcaaa
     6601 gttgttaatt cttcattaga aagtgaaaca ttacgtccta gatgatagat tgaacggcgg
     6661 tttttcaaag tgtcagtaaa agttgtcata ataaaatttc tcctttgatt tgcgttttgc
     6721 atttttttaa ttgattacga aatgaagtat agcaccttac aaaaagtaag taaacagata
     6781 tgctcacaaa aaataagcga agttcaaaaa acaattttaa taagaaaaat cgttatgtaa
     6841 ggattttctt agttatcgct ttcattgttg tgtt
//
LOCUS       DAXLPY010000102         6872 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.104, whole genome shotgun sequence.
ACCESSION   DAXLPY010000102 DAXLPY010000000
VERSION     DAXLPY010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.104"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            27..908
                     /locus_tag="ACF3UF_002511"
                     /pseudo
     CDS             27..908
                     /locus_tag="ACF3UF_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            921..2531
                     /locus_tag="ACF3UF_002512"
     CDS             921..2531
                     /locus_tag="ACF3UF_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3672574.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRMGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2608..3267)
                     /locus_tag="ACF3UF_002513"
     CDS             complement(2608..3267)
                     /locus_tag="ACF3UF_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD3672575.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3550..4215)
                     /locus_tag="ACF3UF_002514"
     CDS             complement(3550..4215)
                     /locus_tag="ACF3UF_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFD3672576.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4362..4967)
                     /gene="dhaL"
                     /locus_tag="ACF3UF_002515"
     CDS             complement(4362..4967)
                     /gene="dhaL"
                     /locus_tag="ACF3UF_002515"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFD3672577.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(4995..6005)
                     /gene="dhaK"
                     /locus_tag="ACF3UF_002516"
     CDS             complement(4995..6005)
                     /gene="dhaK"
                     /locus_tag="ACF3UF_002516"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFD3672578.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(5980..6375)
                     /gene="dhaM"
                     /locus_tag="ACF3UF_002517"
     CDS             complement(5980..6375)
                     /gene="dhaM"
                     /locus_tag="ACF3UF_002517"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFD3672579.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            6529..6849
                     /locus_tag="ACF3UF_002518"
     CDS             6529..6849
                     /locus_tag="ACF3UF_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFD3672580.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
BASE COUNT         1819 a         1444 c         1332 g         2277 t
ORIGIN      
        1 tttttagaaa aaggagtggg gtttttatgg cagaaatcgt caaagtcaca catttgaaaa
       61 agagctttgg tcgtttcgaa gctttaaaag atgtctcttt caccgtacat tcaggtgaag
      121 tcgttggatt tatcggacca aatggttctg gaaaatccac gacgattcgg acacttttag
      181 ggattataaa aaaagacggc ggaacggcaa cgatttttgg gcaagatgta tgggaagata
      241 gtttatctat ccatgaacgt ctttcttatg ttccaggcga tatctctttg tagggaaatt
      301 tgactggagg agcgatcatc gatctcttca tgaagcttca tggaaaaggg agtgctcaaa
      361 aaaaagatga actgattcaa cgtttctctc ttgatcctaa gaaaaaagca aaaaactatt
      421 caaaaggaaa tcgccaaaaa gtgggcttga ttgctgcttt ggctgttgat tcggatctct
      481 atttatttga tgagcctact tctggtttag atcctttgat ggaaacgatt ttccaagaag
      541 aagttgaaaa attgaaagaa cagggcaaat ccatcctact ttcttctcat attctcagtg
      601 aagtcgagcg actagcggat aaagtcgtga tcatacgcga aggaacagtc gtagaagaag
      661 gaacactcga tgaattgcgt catttgactc gttcgaccat cactatagaa acagaagcag
      721 agaatagtca cttagcacaa ttgaacggtg tccatgactt tgtgcaaaaa ggtcacctcg
      781 ctcaatttgc tgctgataac gaagctttcg atgtgatttt agctgaagcg tccaaattag
      841 gtgtgaaaaa atttgaatct attccaccga ctcttgagga tttattcatg agacattatg
      901 aaggatgagg aggaagcgaa atgactgata aattttcacg ctggtccacc cttttttctc
      961 aaaaccttag ccgtgactgg aaaaagatcc tgatatggct agtcggtgtc actgcttttt
     1021 ctggtggttt tgtccctgcg tttgaagaat tgacttccgg acaaggatta gctggattat
     1081 acgaaacctt gcaaaacccg gcaatgattg caatggtcgg accaactcca gcttcgaatg
     1141 ctgctgagta tactttagga gcgatgtatg caaatgaaat gttgcttttt tgcagtttgt
     1201 ttgctgctgt gatctctgtt ttacacgtgg tgagccaaac gagaaaaaaa gaagaacttg
     1261 gtctgattga acttattcgt tcctttcgag tcggacgtca agcaaactct ttagctgtca
     1321 tcgctgaaag tattctgatc aatttgcttt tagcaatatc gatcagctgt acgatgattt
     1381 ttttccaagc agattcgatc actgcagaag gtgcttggct ttttgggcta tctgtaggta
     1441 gtatggggat tttggggagt gccgttgcac tgtttgctgc acaactgatg ccaagttcag
     1501 ccagttcgaa tggtctgtct ttagcgtttt taggtggact ttaccttcta cgagcaataa
     1561 cagatgtagc tgattcctcc ctttcgatgt ggaatccttt aggctggtct tatttgacct
     1621 atccatttac aactaacaac tggattcctt tgctttattt gtttttgttc agtctaatct
     1681 tgataatcag ttcatttgtt ttagaggaac atcgagattt gaacaccggc tatatccccg
     1741 aacgtgaagg aaaaccgtat gctaaacgtt ctcttttatc cttgcgtggt ttattattct
     1801 atctaaataa agggatgaca atcagttggc ttatcacttt tggtttgatg ggggcggcat
     1861 acggctctat ctacgggaat atgcaacagt ttttagaaag taacgactta atgaaacaga
     1921 tgtttatcca atctggcgtc tcaattgaaa aaaactttac aagcacgatc atggtcgtct
     1981 tgatttgtct agctgctatt ttaccaattg ctagcatcaa tcgtttattt acagaagaaa
     2041 cccacggacg tatgaatcag ctgttcgcaa caaaaatttc taggaaccaa ctttattgga
     2101 ccaatatgtt actagctatt ctatttgcta tattggcaat cctgattagt tctggtgcac
     2161 tagggctttc tgctttggct tcgatgaagg atgcgaaaga catggatcta ttgatgtttc
     2221 ttaaagccgg gttcaatttc ctgcctgccg ttttagtgtt tatcggaatt agtggctttc
     2281 tattcggatg gcttcctcga atgggtaaac ttgcttatat ctacttagct tactcctttg
     2341 cactcaatta ctttggcgga attttggatt taccagaatg gttttccaaa acagctgtcc
     2401 ctagctgggt tccacggatg ccaaacgatt cttttgatct ttccgtgttc cttacgttat
     2461 catgtatcag ccttgcactg ttcgtccttg gttctattgg ttataggcga agagacttac
     2521 tagaaggata ataaaaaagc atgtacaatt tcatgctagc ctccaaatct gggtcaaaaa
     2581 tccaacattt ggaggtcatt tttttattta caagtcttct aactgctctt tatcaatgat
     2641 ccagacttct cgattctttc tttttacata accattctcc tctaataatt taaattttct
     2701 agataaagtt tcgggggtcg taccgataaa tgcagcaagt tctttcattt tcattggcag
     2761 gaaaaagtga tccttccctg tcgctttagc taagtcaagc agatagacag cgactcgttc
     2821 ttctactttt tccatcatca aaaaagttgt ctgctgctgt acttttgtta atttctcaac
     2881 gttgattgct aaaagtttca gactaagggc gggataatgc agtaagagtt ccgagaaatc
     2941 tttttgtctc aatatgcaaa tttccgtttt ttctagtgct tcgccaaata aagactcatt
     3001 tggaacgcct agcaactggc tctctccctc atatccgccc ggctctatta ctcgtaaaag
     3061 ctgttccttt ccgctagcag ataattgata cactttcata ctgccggagg ccacgatcac
     3121 taattgaggt tctccattcg gcgcaagaat ctgttctcct ttttccacat agtgatgttt
     3181 gacaagtgcg tgtacttttt cttgatcttg ctgtactaag tgattgaaca aaggaacaaa
     3241 tgaaacacat aaatgatcat gactcataat ctctcctcct tctaaacagc tatttctaat
     3301 aaagaaacat aacttccctt attccaactg ataattttct tttatcatag cataaacgtc
     3361 aagcgaacca gataccagca aatagagtgg atttcttttt gtcccttgct ttattttcct
     3421 tcttttgaga ccttaagtaa ttgattccta tcaatttttt aaatatttac tttttgaata
     3481 atcaaaaaca aaccttcact cgcaagccga gagtaaggtt tgtttttcgc attgcttatt
     3541 tcgtgttgtc tattgaaatt tttccgcacc tagcttttga tatagtggtg ctagttcttg
     3601 taaggtttca gcggttattt gctcaacgtg ttcgatttct tgcggataga agaatagttt
     3661 acccatttga aaggttcggt ctctcatcgc ttttttcaac tcttcttgtt tctttgtatc
     3721 ggacaaatag tcagacaaag ctaagtggtc gtcaagttca tgttctggtt gcggccatat
     3781 gtaataatcc ttgatatcga ctgttttgct ccactctttc agtatcgcaa gcaactggtt
     3841 atacgctgca atgctaccat atcgttcttc gcttttataa tgttggtaca tcaaatagat
     3901 ttggtattgt ttttgattca acaaaactgc tagacaggca ttctcgtctt gacgagattc
     3961 gcttcggtac gcgctccaaa aatgactgcg taaattccag ccattcgtcc agctttcgat
     4021 tttaggtttg ctcatgccgt acatatcagg caaaagtgca gctgtctgga gctgaatctc
     4081 tttccatttt tgccagtgtt ctttatattc tttcttgatt tgttcaatct tatctgttgg
     4141 atggctctct ttgagctgtt tgaatgcgta gattggtcga tcaaacaact gataatctga
     4201 ttttccaagt tccattgttt cgcctctttc cgttatcttt tgtattctac ctgaattttg
     4261 cgatatggac aaatagaggt tgtgaaaaag ctgttctgca tcaagtcata agaacagcca
     4321 aacaaaaaac tgcgatgagc atcaccgcag ttttattgaa cttaaggttg attgatcaca
     4381 tctaaaagcg ttgaaaataa aatggcacta gaagcagctc ctgggtcgat atgtccgatt
     4441 gcacgctctc ctagatagga agctcgtcct tttttagcta ccaagacttt ggtgtgttct
     4501 tttgcctggt caatgatttc ttttgttaaa ttccctgcct tcaatgcctc tgtgactggc
     4561 agccaaacat ctaacatcgt tttatcgtca gcttctgcct ttcctcggct ttgaataccc
     4621 gctgttccct gctcgatcac ttcgcctaat ttttcttgag aatcaataga atcgacctct
     4681 tttgtcgctt tcatcatgtt catgaatgca gatccgtata acggaccaga agccccaccg
     4741 actttcgata tcatcgccat agagaatact ttgaatgtat cgctgattgt ttcaggatga
     4801 tcggcttgaa aagcttcttc ataagctgaa acccctcttc ccatgttatt tccatggtct
     4861 ccatcgccaa tcggggtatc tagatcactg agatattgtt tgttctgatt gattgcctct
     4921 gcaaattgcg tgagccattc ttggatttct tgaacggtta gtttcatatt atcacccttt
     4981 tatcttgaga ttttttacca tgaaatcgtc tgtacattgc tttctaaaga atctttccat
     5041 tgtgtctccg tcaagtcgat cagtgttaga gaaagacctt gcatatctag tgaggtcata
     5101 aaattaccga cttttcggaa aactacattg acgcctcttt cttccaacag agctaaaaca
     5161 tcattcatga acacgaactg ttccatcaaa ggcgtcccgc ccattccgtt gactagtaca
     5221 cctgcttctt ttggtaaatt cgagtaatca tctaaaatct tagtaacaag ttcctttgcc
     5281 agtactttag aaggctgcat cttttctcga cgatagcctg gctcaccgtg gataccaaca
     5341 ccatactcga tctcatcttc tcctagttcg aatcctggtt tccctacttc tggtacagtt
     5401 gctgctcgaa gcgctagacc gatcgtctta gttgcctgta cgaccttttc tcccagttct
     5461 ttcaactcag ctagggaagc accgtttctt gctgcatcgc ccacgatttt gtgtacaagg
     5521 acagtacctg caactccgcg ttttccagca gtatacgtac tattttcaac ggcgatatca
     5581 tcatctacga tcacactttc tacttcaata tcgtccatag cagctaattc ctttgccata
     5641 tcgaagttca atgcatcccc tgtataattc ttaacgatca gcaaaactcc ttttccacta
     5701 tccgcttcct taatagccgt ctgaatctga tctggagttg gagaagtaaa cacatcacca
     5761 agcaccgctg cacttaacat cccttcccct acaaacccgg catgggatgg ttcatgtccg
     5821 cttcctccac cagaaaccaa accaacttgt tccgctttct gattcttggc tacaacacgg
     5881 gaagattcta cacgatgaac aagttctgga tagcttttta ctaatccttc cagcatttct
     5941 tcgacaatat tgcttggatc attcatgatt tttttcaatt tattcccatc ctttctttcc
     6001 ggcattttgt gcttctgtta agatttgctg agtatcatct gttataccgg cagtgatggc
     6061 tgctgcaaaa gctccttcca ctaaaggcgc atccaccaga tgataacgtt gctgctgctc
     6121 ttcttccaac atgtcttttg ccagttccga gttcaatacc gcgctaccga tatccgcaaa
     6181 aacaaaataa ctagctgcat cgcttgattc attgactgct tctacgattt tcatcgggtc
     6241 tgatccgatc tcgccattta ttccgccgag agaaaaaatt tgcacctctt cggatttttg
     6301 catctgctca atcatttctt taataccatc tgttactttt tgactatgag aaataagcaa
     6361 aatacttttt ttcacaagaa tcttcctttc ttttacatag ttgctaacga ttggtttcgc
     6421 tttcattaat gaacaattca agtatataat aaatttctaa ttttgggaaa atatgtgtag
     6481 tgcttcttga agtttgttat actttaatta aaagagagga gtgatcgaat gattacaaca
     6541 acaacgaaca gtgtagaggg aaaagccgta gtagcttata aagggatcgt ttttggtgag
     6601 gtcattactg ggatccatgc atttaaagac ttggaggcgg ggttgcgaaa tatctttggc
     6661 ggccgctcaa aaagctatga aaacgaacta atgggtgcaa gagaagaagc acttgccgaa
     6721 atggccgaac gtgcaaaagc attaggagct gatgcgatca ttggcgtaaa aatggactat
     6781 gaagtattag gcagcgacaa tggcatgctg atggtcacat gtagtggaac agctgtctcc
     6841 acgagataag taggggacat ctgttttaat aa
//
LOCUS       DAXLPY010000103         6603 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.105, whole genome shotgun sequence.
ACCESSION   DAXLPY010000103 DAXLPY010000000
VERSION     DAXLPY010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.105"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            374..973
                     /locus_tag="ACF3UF_002519"
     CDS             374..973
                     /locus_tag="ACF3UF_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3672581.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLSDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQVHDFSKYLFPSRKLADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            1022..1492
                     /locus_tag="ACF3UF_002520"
                     /pseudo
     CDS             1022..1492
                     /locus_tag="ACF3UF_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405176.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1706..1969
                     /locus_tag="ACF3UF_002521"
     CDS             1706..1969
                     /locus_tag="ACF3UF_002521"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672582.1"
                     /translation="MKQIQNDLYGNIEKEYFDSQMFQQNSSPYYSEERFFQLMEQEEE
                     KRLLQLMKEMEEQQVAEEIEEKRFIKLIEEQMEIESLREQEEE"
     gene            2117..4219
                     /locus_tag="ACF3UF_002522"
     CDS             2117..4219
                     /locus_tag="ACF3UF_002522"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000921212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HFD3672583.1"
                     /translation="MMTTQDLMDKYEVSRQTVNNWVRKNEIPAPTVKKGHQNAWTFSQ
                     AELIDKKLKHSHSEQLELFKTESTPLHINNRRYLGSKQKILDFINDVVSEHTKNVKSV
                     ADVFGGTGVVANLFNKQGKKVIVNDILTSNYISYETWFGNMPVDEKKIQFKIEELNSL
                     EGIHGYVDKNFGNKYFSVENAQKIDAVREKIETYNDLNEREKAFLLTSLLYAMDKVAN
                     TVGHFDAYRKKMDTFKPIYLRVPEFNKNVGNEIYNEDANQLVRKIKTDLVYIDTPYNS
                     RGYESAYHVLENVMEWKKPDVEGVAMKAVNRSEKSSDYTKSKAPQAFDDLIQNINARY
                     ILVSYNNMAKKGNSRSNAKISNEEIIATLKKRGQVEVFSIDFNAFTTGKSNIENHKEL
                     LYLCTVDDEIIQSPLNYTGGKQKLIPQLRPYFPSRYTRLIDLFSGGGSVTANLAKNGQ
                     AESYLMNDVENHVINFFEYISTIDIDDFINQAEMKISEYGLSNTKKNGYEFYSANSAS
                     GLGAYNKEKFLKLRKDYNNSPSPLLFYLLVVFGFNNQIRFNSKGEYNLPVGKRDFNKK
                     MEEKLRKFVKVIQDSPIEYSTKDFREVSIDTGDFIYADPPYLITTAAYNENGGWSEKD
                     EKDLYDYLDKANENNIKFALSNVIIHNGRENEILKSWASKYNLYVLNYNYNNSNYQSK
                     AKQSETVEVLVTNYERDI"
     gene            4219..6174
                     /locus_tag="ACF3UF_002523"
     CDS             4219..6174
                     /locus_tag="ACF3UF_002523"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF021040.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlwI family type II restriction endonuclease"
                     /protein_id="HFD3672584.1"
                     /translation="MKLTNTAETFNLGDTSFRRKTLIDDYKTLLPYLQETNLEFNEWN
                     NVAQAEFYEKILTKTDLFSRNTDEDFAKRGRTLTNALVKIGLTNSKRKLSRVANSWIN
                     ENTLSANDVERSLGIDANNLLFTRQLLKLRVYDSNKMNYFYPFRVALGLVIKYQNIPQ
                     QDFLTLIHLIQPSFDNRKIKDIINDYHSVNDNNEIFSEFLDRNFPENTSELTADELFS
                     KKPLNRKEFDSLFVNRKSSATQGIYFEFVNKLLAFKSNKNVENLDALLELNSNDKLTK
                     AFGFGKAIFAKTNFMKSKNIQDFLDENVDNDLLSENNTLIYNQFVLSKKDDIVREYRD
                     MTKRTFNLSGLLDFNTGLVNATNQDVLSIIFSSMSFSGTENYADYEENLSYSFYQEST
                     ITEVLDLDESAILSEIKAFLGIENTSQIESVVLTQKEDKFRKFISKTFPREKIIEILP
                     LFSPRDDKKIKSEVSESATVPTIYEYIVAIAWFYISKEEFFITKSLNLTLDGEMRPLS
                     HAAGGAGDIVIDYENLTLMLEVTLMNAQAQKRGEWEPVLRHATNLTVDNFDKNVITLF
                     IADELDDNTVNIWRAVASVPLRSSNKDEIADLVKIFPLENRELLHMLKNNLDERKLLK
                     AIDESYEELAGNFDLSWRDKIFVEANM"
BASE COUNT         2398 a          955 c         1235 g         2015 t
ORIGIN      
        1 gattcatcgt cattcctcct gctatctttt tctattattc taccttattt gatagtagat
       61 ttaaaacttt gcaacagaac cgttaattat atagactgaa aattttgaat tttcagaata
      121 gaacaactta aaagtactga caaaattttt taaaggggca atattaatgt tctgagataa
      181 tcaaatctta ccgaaaatct caaaagtcca atgtgacaca agctgattct gtcacattcg
      241 ttaaaatcgc tccatcctta gaggctctaa gaggaaatca cttttctttt agggcctttt
      301 ttctatagct tgtttaaatg tgacttatta tctgttataa tcatattaag taacatttga
      361 gaggggacta aaaatgaaga gcgtggaacc gattcgcgac aaaaaaaaga tcgatgccat
      421 gaaggccatt ttggcttccg gaaaatatgg gcaacgaaat ttggtgcttt tttcaatcgg
      481 gatcaataca gcctatcgaa tctccgattt aaggcagttg aaattaagtg atgtgttaga
      541 aatttcccgt gggcgggtga ttgtcaaaga acgtctggcc atgaaggaac aaaaaacggc
      601 caaacataat tcggtcttca tttcaaacaa attacgaaaa gtgattctcg attatgtcca
      661 atccgaattt cctgagcagc tgcaagtaca tgacttcagc aaatatttgt ttccaagtcg
      721 aaaattagca gatacgcctt tgacccgaca aagcctttgg cggatcattc atgaagcagg
      781 aacagcggtt ggtttaaaag aaattggtcc ccattcgatg cgcaagacct tcggctattt
      841 tttgtacaag caagggacca aaacagagat cattcagtcg ctgctcaacc attcttcgca
      901 acgggagacc ttacgctata ttgggatcac ccaggaagat aaagataccg cagtaaagag
      961 tttggatctg tgacagaata atgccctata taatagaaga aaaaattcaa gaggggagaa
     1021 gatgaacgaa gaaaagcgtc cgaaatttcc tgataaatac cacttatctc gcaaagagtc
     1081 tgtgtattta ttgaagaaaa acattgtgga actggtgtat aatgcgggaa aatttgaagg
     1141 gttaaataca acgctattac aaacagaaga gattatcaag tataatcgag ctaataatat
     1201 ggcggtagat gatgtcctga ccgtcgttaa cttaaaaaga ggctttgaaa tgcttttaaa
     1261 cgacttacag gagcccctaa tagagacaag taagcggatt aatcggatcg ttgcagcaga
     1321 ggatgcgctt ttttccggtg aaatacgaac tggtggggta gaagtatcga cgattcaagg
     1381 aagatatgtg ccaccaatgt taactgaaga cgaggtaaac aatcaatatg gtgagataat
     1441 gaataaagag atatcagata cggaaaaagc cctgcgactg tttctattca tttaatgcaa
     1501 taggagcggg tatttgtaat gcttcccata gtgccacccc atttttgaaa tcaatttccc
     1561 acgtttcttc gttctcgcca ttctttggga gaagctcaag agatggcgga gtaaaatcaa
     1621 attcgctttt cattatatta attgtctaac ttaatttgac aattaatatt atttatacag
     1681 cacaagtgag aaatatattg aacagttgaa acaaatacaa aacgatttgt acggtaacat
     1741 tgagaaagaa tattttgata gtcaaatgtt ccaacaaaat tctagcccct attattctga
     1801 agaacgtttt tttcaattaa tggaacagga ggaagaaaaa agactacttc aattaatgaa
     1861 agaaatggaa gaacaacaag tagcggaaga aatagaagag aaacggttta ttaaattaat
     1921 agaagagcaa atggaaatag aaagtttaag agaacaagaa gaagagtaag ttctgcgttt
     1981 gttagaaaca taatatcttt gaaaacaatt tagacaaacg acaggaaatg gtaatttgaa
     2041 aactaaacat tgataattac ttattgcact taatatggta gaattgcatt aactgtaaag
     2101 agagggtgat gcctaaatga tgacaacaca agatttaatg gacaagtacg aagtatcacg
     2161 acaaactgta aacaattggg ttcggaaaaa cgaaattcct gcacccacag taaaaaaagg
     2221 gcatcagaat gcttggacat ttagtcaagc ggaacttatt gacaaaaaat tgaagcatag
     2281 tcacagcgaa caattggagt tgtttaaaac tgaatcgact cctcttcata tcaataatag
     2341 aagatattta ggcagtaaac agaaaatact agattttatc aatgatgttg tttcggaaca
     2401 caccaaaaat gttaagtcag ttgctgatgt ttttggtgga acaggtgttg ttgctaattt
     2461 atttaacaag caaggcaaaa aagtcatagt taacgatatt cttacaagca actacatttc
     2521 ttatgaaaca tggttcggga atatgcccgt agatgaaaaa aagattcagt tcaaaattga
     2581 agaactgaat tctcttgaag gtatacatgg atatgttgat aaaaattttg gtaataaata
     2641 tttttcagtt gaaaacgcac aaaaaattga tgcagtccgt gaaaagatcg agacttacaa
     2701 cgatttaaac gaacgtgaga aagcattttt gttaacgtct ttgctatatg ctatggataa
     2761 ggtggctaac acagtaggac attttgatgc atatcggaaa aaaatggata cctttaaacc
     2821 tatttattta cgagttcccg aattcaataa aaatgttgga aatgaaattt acaatgaaga
     2881 tgctaatcag ctagttagaa aaattaaaac agaccttgtt tacattgata caccttataa
     2941 ttctcggggc tatgaaagtg cttatcatgt tttagaaaac gttatggaat ggaaaaagcc
     3001 ggacgttgag ggagtggcaa tgaaagcggt caaccgctct gaaaaatctt cggactatac
     3061 taaatctaaa gcaccccaag catttgatga tttgattcaa aatattaacg ctcgatatat
     3121 tttagtttcg tacaataata tggcgaaaaa aggaaattca cgttcaaacg caaagatttc
     3181 aaatgaagaa attattgcca cattgaagaa acgtgggcag gtagaagttt tttcaattga
     3241 ttttaatgct tttacaacgg gcaagtcgaa tatagaaaat cataaagaat tactgtatct
     3301 ttgcacagtt gatgatgaaa taattcaatc gccactgaat tatacgggcg ggaaacaaaa
     3361 attgattcca caattacgac catattttcc ttcaaggtat acacgattga ttgacttatt
     3421 ttctggtggt ggtagcgtta ctgcaaatct ggcaaaaaat ggacaagcag aaagttatct
     3481 tatgaatgat gttgaaaatc atgtgattaa tttttttgag tatatttcaa ctattgatat
     3541 agatgatttc attaaccaag cggaaatgaa aataagtgaa tatgggttat ctaatacgaa
     3601 aaaaaatgga tatgaattct attctgcgaa tagtgctagt ggtttaggtg catacaataa
     3661 agaaaaattt ctgaagctaa ggaaagatta taataattca ccgtcaccat tgctatttta
     3721 cttgttagtt gttttcggtt ttaataatca gattcgcttt aattcaaagg gtgaatataa
     3781 tcttccagtt ggtaaacgag actttaacaa aaagatggag gaaaaattac gtaagtttgt
     3841 aaaagtaata caggactcac caattgaata ttccaccaaa gatttccgag aagtgagtat
     3901 agacacagga gatttcatct atgctgatcc gccgtatctt attacgacgg cagcttacaa
     3961 tgaaaatggt ggttggtctg aaaaagatga aaaagactta tacgattatc tagataaagc
     4021 aaatgaaaat aatattaagt ttgctctttc aaatgtgata attcataacg gaagagaaaa
     4081 tgaaatcctt aaaagttggg cttcaaaata taatttgtac gtcttaaact ataattacaa
     4141 taatagcaac tatcagtcca aggctaaaca aagtgaaaca gttgaagttt tagtcacaaa
     4201 ttacgagagg gatatttaat gaagcttaca aataccgcag aaacatttaa tctaggtgac
     4261 acaagtttta gaagaaaaac attaattgac gactataaaa ctttgttgcc ttatcttcaa
     4321 gaaacaaatc tagaattcaa tgaatggaat aatgtcgcgc aagcagaatt ttacgaaaaa
     4381 attttgacaa aaacagattt attttctagg aatactgatg aggattttgc aaaacgtggg
     4441 agaaccttaa ccaatgcctt agttaaaatt gggctaacaa attcaaaaag gaaactttca
     4501 agagttgcta atagttggat aaatgaaaat acgcttagtg caaatgatgt tgaacgttca
     4561 ctaggaattg atgcgaataa tttattattc actcgtcagc tgttaaaact acgtgtttat
     4621 gattcaaata agatgaatta tttttatcca tttcgtgtcg cattgggatt ggtgataaag
     4681 tatcaaaata tcccacaaca agattttcta acactaattc atttaattca gccgtcattt
     4741 gataatagga aaataaaaga catcattaac gactatcaca gtgttaatga taacaatgaa
     4801 attttttcgg aatttttgga tagaaatttt ccagagaata caagtgaatt gactgctgat
     4861 gaactttttt caaaaaaacc attaaataga aaagaatttg attcgctgtt cgtgaataga
     4921 aaatcttcag ctacgcaagg aatatatttt gaatttgtaa ataagttgtt ggcgtttaaa
     4981 tctaacaaaa atgttgaaaa tttagatgct ttgcttgaat tgaattctaa cgataaatta
     5041 acaaaggcat ttggatttgg aaaagctatt tttgctaaaa cgaattttat gaaatctaaa
     5101 aatatccaag attttttaga tgaaaacgta gataatgatt tgctgtcaga aaataatacg
     5161 ttgatttaca atcaatttgt actttctaaa aaagatgata tcgttcgtga gtatcgagat
     5221 atgacaaaac gaacattcaa tttatcggga ttattagact tcaatactgg actagtcaat
     5281 gctaccaatc aagatgttct ttcgataata tttagttcta tgagtttctc gggaactgaa
     5341 aactatgctg attatgaaga aaacttgagt tactcattct atcaagaatc tacaataact
     5401 gaggtattgg atttagatga atctgctatt ttgtcggaaa ttaaagcatt tcttggaatt
     5461 gaaaatactt cacaaatcga aagtgttgtt ttaacgcaaa aagaagataa atttagaaaa
     5521 tttatctcaa aaacatttcc tcgagaaaaa attattgaaa tcttaccgct attttcaccg
     5581 agagatgata aaaaaattaa atcagaagta tcagaatcgg caacggttcc aacaatttat
     5641 gaatatattg ttgctattgc atggttttat atttctaaag aagaattttt tattacaaag
     5701 agtttgaatt taaccttaga cggtgaaatg cgtccgttat cacatgcagc tggtggtgct
     5761 ggtgatattg tcattgatta tgaaaacttg acattaatgc ttgaagttac tttgatgaat
     5821 gcccaagctc aaaaacgtgg agaatgggag ccagtattac gacatgcaac aaatttgacg
     5881 gtagacaact ttgataagaa tgtcattact ttatttattg ctgatgaact ggacgataat
     5941 actgtaaata tttggcgagc agttgcaagt gtacctctac ggtcatcaaa taaagatgaa
     6001 attgcagatt tagtaaagat tttccctctg gagaatcgag aactacttca tatgctgaaa
     6061 aacaatctcg atgaacgaaa actattaaaa gcaattgatg aatcatacga agaacttgcg
     6121 ggcaattttg acttaagttg gcgagataaa atttttgttg aagctaatat gtaaaaatgt
     6181 agtagtttcg atttaaacgg gaatgttttt tagtcaatgg aaaatatcac ttaatggtgt
     6241 gaacttatgg taaaagctag ctcaattcgt tttatttagg gttaaaattc acaccattca
     6301 aatgatatta gttgaaatta gatgaagttt tgttatttgc aatcgcccaa aagatttgat
     6361 aataaaagct tttgaaagtt attcaattag gcgttgttca agccaggtct taaaggcgct
     6421 cgtcgttcac tacagttctc aacgttaata tcgttgctat ttcaacgttt acagcactct
     6481 ttggattatt tcaaagagtg tttttttgta tttttataga ggtatttaga taagtttgtg
     6541 gaggtttgtt gcgctttatt ttgctatcca ggagttcatt attttaaaag cttaaataat
     6601 aag
//
LOCUS       DAXLPY010000104         6589 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.106, whole genome shotgun sequence.
ACCESSION   DAXLPY010000104 DAXLPY010000000
VERSION     DAXLPY010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.106"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            203..682
                     /locus_tag="ACF3UF_002524"
     CDS             203..682
                     /locus_tag="ACF3UF_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFD3672585.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            715..2943
                     /locus_tag="ACF3UF_002525"
     CDS             715..2943
                     /locus_tag="ACF3UF_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3672586.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3072..4715
                     /locus_tag="ACF3UF_002526"
     CDS             3072..4715
                     /locus_tag="ACF3UF_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFD3672587.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4788..5333)
                     /locus_tag="ACF3UF_002527"
     CDS             complement(4788..5333)
                     /locus_tag="ACF3UF_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFD3672588.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5356..5841)
                     /locus_tag="ACF3UF_002528"
     CDS             complement(5356..5841)
                     /locus_tag="ACF3UF_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3672589.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5831..>6589)
                     /locus_tag="ACF3UF_002529"
     CDS             complement(5831..>6589)
                     /locus_tag="ACF3UF_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFD3672590.1"
                     /translation="QTDLKTFENFGLFGLSALTSIGALDINERFMLESISLELLKRQL
                     VSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIILDPVLAFKETEAVINQLYI
                     SQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLAKELTASGTKNIVIKGGTR
                     MAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAITANLVLGADFTKAVAESK
                     KFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
BASE COUNT         2261 a         1239 c         1329 g         1760 t
ORIGIN      
        1 atattccaac atcatcttgg actttctaca tgttactaat gagcgtgtaa aagaacgaga
       61 tggtgttttt atttctatca atgaagctct ttttctttgc aatcctcact tcaatcctct
      121 ataatgtcgc atatagttta gtaaatgagt aaactactaa tttacttatt tactaaaaat
      181 aaaaggatga ggagttaaaa taatggaaat accaacaaat ttaaaacata aaccagtaat
      241 cgttgtagaa gactatgata aagttgatgg aagaaatgca ttaaatatgg atgcaaaagg
      301 gctttcactg ggccttgctc agtggaatga tcgtggaaaa gtcgatatct caggcaaggt
      361 atggcgacat actggagaaa aatggtcacg acagtcggaa gaattaccaa tcacacgtat
      421 tttagattta gcgatcttag ctgcgcaagg aagtttatac ttccaagatg cttatcgtta
      481 tgaaaaattt tatgatccag aaaatccagt cgtagacatc attggattac aagggaaccg
      541 aatgacggta gaagtagata ccaaaaatcc aaagatcgat gaagacatca ttttgtatta
      601 cgatacacta caaaaagacg gagaactgat tggggaacga ttccgtattt taaaacgtct
      661 tttagatgag ctaggatatt aatagacaga gatgatcaaa aggggaagag aagcatggag
      721 aatttctcac taacagaaaa ccgaaccttt tcacggctag aaaagcaaat gatctggaag
      781 aaaccgaaaa gccatcggac aagtgcagaa gaatggcgga tcgcctccga aatcaaaggg
      841 aattggcaag atcctgaaat gaaaatcagt aacgtacttt tggaaggaga tgccgggtcg
      901 gggaagacac aattagccaa agcactatct gctgatctgc aacttcccta tacaaaagtg
      961 acctgttttg cagatatgga caaatcagat gttttcggag ccttattacc tgtagtagat
     1021 tctaataagg aacaagacca agaattacta gaagctattt accaaacaga tacacttgaa
     1081 gctgtactga cactgatcca gaaccattac ggcattgatc ctttttctgc taaagaaaaa
     1141 ttagcagagc tagttcaaag gatcgaagct gattatccag atgcaatcca ttacagctat
     1201 tacccttctg aaatcgttcg agcgattgaa aaaggctatt tattagagat tcaagagccg
     1261 actgtcatcc gagatgcctc tgttcttgtg gcacttaact cagcgctcga accaaatggg
     1321 atgttgaatt taccgacagg aatcattcgt cgccatccag attgcgtcat tgtgatcact
     1381 acaaatcgaa attaccaagg aaatcgccca ttaaatgaat ctttaagaga tcggatgcaa
     1441 catgcggaaa aaatggatct tcctgcctta gaagtcatgg cagaacgtgc gatggcgaaa
     1501 actatgatcc aaaaacaaga acttctctta aagatggcag agattatccg tttgttggat
     1561 gaaactgcaa aagctaacgc catcaaaggt gtagcaggaa tgcgttctta tttttattgg
     1621 gcaaatacct ataagcaagg acaagattta ctccagtcga tttatccaaa agttttgtat
     1681 aaattatcca ctgattcaga tgaattggca attcttgaac aagctttgtc tgacagtgga
     1741 ttgctactgg aacttcagga catattgaga aaagaaaaat ggggtcatcc tcaatctgag
     1801 catacaaaag aaagaaccat tagcgccgaa gaagcaaatg aacgaaacat cactgaaaat
     1861 gctgaagaaa ttctgcgctt agatgaaaag aaatcgttgt ctgctgaaga accaaatgag
     1921 ggagaagaga aacaagaaga aacaatagaa aaaaacgaga ttcctcctca aatgcaaaaa
     1981 gaacgcagta gcgatatcga aggaaaaaat caaaaagaac aacaaacagg agatgattct
     2041 caagaaatgt ctgcttctga catggaagca catgataagg aaatcaagaa gcaactgaat
     2101 aaagaagcgc gacaaatcat gaaggaaacg attcatgaaa aagaaggtct catcgttcac
     2161 cgaccagctt tccaaggaaa aacgccggaa gcacgtgagc tacacatgca agtaatgcca
     2221 atagtagaat cacttagccg gcaaatttta gagttactgg ataatgaaca aacagagacg
     2281 taccaaaaag gaaaatacga aggtcagcgg ttcaatgcaa gcaaagtagc atatggtgat
     2341 ttgagaaatt ttgacaaaaa gaacccgcca catgagcaac cttctttagc ggtagctgta
     2401 cggatcgatg aatctgggtc aatgatacgg gatgatcgga tcgaagcggc aaaaaaagca
     2461 gcgattgcca ttgccgaatt ttctaagaaa gtcgatatcc cattgttgat ttacggagat
     2521 acagcagacc gttcgtcaag agaaaagact tctttgtttt cttataaaga atttgaagac
     2581 ggatttcaat ggttaaatga aaaattagtc actatgaaac caaggcaaaa caatcgtgat
     2641 ggtgctgcac ttcgtttagc agcagaaaaa ttaaacagac aatccgcaac aaccaaactg
     2701 ttgcttaata ttagtgacgg tcagccaaaa gcgttgccgg attatacagg caaaaaagca
     2761 aaagaagata tccagtctgt tttgaaagaa tatgaacgtc aaggaatcct atttgtctcc
     2821 gcagctattg gccaagacaa agaagaaatc aagtcgatct acggtgaaag tcgttttgta
     2881 gatattactg acttgaatga atttcccaag caaatgattc aactgattgc ccgctatcta
     2941 tgataaaata aagctcaacg aacgcactta gcagattcgt tgagcttttc gtttctagtt
     3001 accggtaaca aggatacttc taaaatagaa tcggttataa tcaagaggga ccgttaaagg
     3061 agtgaaacga tatgatacaa gaacaaaaat ggtggaaaga agcagtaggc tatcaaatct
     3121 atcctgctag tttcaaagat agcaatggcg atggtcaagg agacatcaat gggatccgtg
     3181 aaaaacttaa ttatttgaaa gatcttggta tcggctttat ctggatcaat ccgatctatc
     3241 aatctccatt tgtcgataat ggttatgacg taagtgacta tcaagatata gaagagagat
     3301 tcggaacgat ggaagatttt gatttattgc taaaagaagc acatgaatta gggatcaaag
     3361 tgattatgga tcttgtcatc aaccatagtt cggatcagca tcaatggttt gaagaatcga
     3421 aaaaatctaa agaaagcccg tatcgcgatt attacatttg ggtcgacggg gtagatggca
     3481 aagaaccgaa taattggaca tcgattttcg gcggttctgc ttgggagtat tctcatgaaa
     3541 ctggacagta ttatctgcat gtttttgcaa aagaacaacc agacttaaat tgggaaagcg
     3601 agaaattgaa agaagaacta ttcaatatga tccgatggtg gttggataaa gggatagatg
     3661 gatttcgttt agatgcgatt tctcatgtaa aaaaagatga atattcagta aaagccacag
     3721 agaacccttt ctcacccttt caaaatgtct caggaatcga agaacatttg accgatttga
     3781 aacatgtttt tgaagagtac gatatcatga ctgtcggaga agcaagtggt gtcactgcag
     3841 aagaaggacc acaatgggta gggaaagacg gttatttcga tatgatattc gaatttgatc
     3901 atatccatat ctggcagcaa gaaaaagaag ggcaattaga tgtccttaaa ttgaaacatg
     3961 cattaagcgc ttggcaaact tcattggatg gtatcggatg gaacgcttta tatatggaaa
     4021 accatgatgt tcctcgtgcc gtttcagtgt ttggagatac tcgtcccgat ttttgggcta
     4081 tgtctgcaaa agcaatcgct atgatgtatt tctttttgca aggtacgcca tttatttatc
     4141 aaggacagga aatcggaatg acgaatatgc cctttgaatc gatcgatcaa gttgatgcag
     4201 tagattcgaa aagactttat aaaaggctgc ttgcggaagg taagacaaga gaagaagcat
     4261 tggatatcat tcgtgaaaca acgagagaca acagcaggac acccatgcaa tggacttcgg
     4321 aacaatatgc tggtttttct acacatgaac cttggctgat cactaatcca aataccaaaa
     4381 cgatcaatgt agaacaacaa gaatatgaac cagagtcggt cctgcaattc tataagaaca
     4441 tgatccgcat tagacaaacc aataaaggtc tgatatacgg ttcttataaa gaatatcttc
     4501 atgaacatcc acaactttat gtctatgaaa gatatttaga agatgaacaa tatcttatta
     4561 tggtaaactt aacagaatca cttgctgact atgaacttcc aaaagaagca gatcagtcct
     4621 ggacattact cttgtcaaat tcctctagcg gagaatttga agctaaaggc atactagcac
     4681 cttatgaagc tcggttatat aaaacaaaca agtaaaactt cctcgttaaa gttcattagt
     4741 tggactttgc gaggaagttt ttcagattgc tctgtcaatt actcatttca ataattcgct
     4801 ctaggaccac cgatatattt aggacgagag cgaagggctg tcacgtgagc ttgtccaagg
     4861 gttttcaaac gaggtctgac aggtacttgg acatgcttga tatgcatacc gattgatgtg
     4921 tcaccgatat cgataccggc ttgtccaact acgtgttcca cttcgacagg atcattgaac
     4981 tggtcaaaag cagcaacaga acaagcacct ccagcatgta gtgcaggaac aacagagaca
     5041 atttcgaaat tttttgcttc tgccactgtt cgttctacta ctaatgctcg gttcaaatgt
     5101 tcacaacctt ggacagctag cgcaatttct ttaggatcca acaactcttt taacgtacgg
     5161 atgatccatt gaccaacttc cgcactggaa ttttttccaa tatgtcctcc aacgacttcg
     5221 cttgtgctgc atcctaaaac aaaaagatca ccttttttca agtgtgcctc agccaatatg
     5281 tcattaacta tttcagtcaa ttggtctttt aattcttttt ctgacaactt cattttctaa
     5341 aaccttcttt ttcaattaat attgcttccg tgcttgaata cgttgaagac ttgcagttat
     5401 aggaaaggca agtcccattc caatcagatt ttggaagatg tttcctggta tagaagccac
     5461 tccagccggc caatcatata aaatccaacc ggcgatacca tagccgatga tcataactaa
     5521 gcttcctaat aaaagcccta atccccacat acgagtagaa gatttgctga aagaaccagc
     5581 aacatatcct tgtaacccgt ggatcactaa tgaaaaaact gcccactgcg gatatcctga
     5641 aatcaaatcg atcaatagac cactggaagc accaacaact aatccacccg ttggaccata
     5701 aagaaaagca gcggtataga tcccggcctc gcataatgtc acaaatccat tcgtagccgg
     5761 tacagggatc aaaattgtta atgaaagggc aactgtcaac gcaatcagca tagcatagat
     5821 cgttaattgc ttagttttca tttctcattc ctcctttttg aataccgcca gaccagacac
     5881 ttccggtatg atcgttcatc agcacgccat tagaaataca atgggcaaca aattttttac
     5941 tttctgctac tgctttggta aaatctgccc ctaacacaag attcgctgtt attgcagaag
     6001 aaaaggcaca accggccccg tttactgttg tagtgtcgat ttttttatga gaaaatacct
     6061 cataatgatc aattgaatag agaagatcca cagcttcatc tccagccatc cttgtgccgc
     6121 ctttgatcac aatgtttttt gttcctgaag cagtgagttc tttagcgaga tggatcattt
     6181 ctgttaacga agagggaaga gcttgaccag aaagtaaagc agcttctgcc aaattaggcg
     6241 taatcatcgt aacaagtgga aaaagttctt cgatgagctg cgaaatatac aattgattga
     6301 tcacagcttc agtttctttg aatgccaaaa cagggtctaa aatgattggg atattttgtt
     6361 ttgtttttat gaagtctcga acaaccatga ttgcttcact tgaattcaat aacccaattt
     6421 tgataccatc taatgaagtc attttatcaa tcgaaactaa ctgtcgttta agcaattcca
     6481 aagatataga ttccagcata aatcgctcat taatatctag tgcccctata gaagtcaagg
     6541 cgcttagtcc gaatagacca aaattctcaa aagtttttaa atctgtttg
//
LOCUS       DAXLPY010000105         6434 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.107, whole genome shotgun sequence.
ACCESSION   DAXLPY010000105 DAXLPY010000000
VERSION     DAXLPY010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.107"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(133..717)
                     /locus_tag="ACF3UF_002530"
     CDS             complement(133..717)
                     /locus_tag="ACF3UF_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672591.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(928..1131)
                     /locus_tag="ACF3UF_002531"
     CDS             complement(928..1131)
                     /locus_tag="ACF3UF_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672592.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(1141..1563)
                     /locus_tag="ACF3UF_002532"
     CDS             complement(1141..1563)
                     /locus_tag="ACF3UF_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672593.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1801..2415
                     /locus_tag="ACF3UF_002533"
     CDS             1801..2415
                     /locus_tag="ACF3UF_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672594.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(2580..3404)
                     /locus_tag="ACF3UF_002534"
     CDS             complement(2580..3404)
                     /locus_tag="ACF3UF_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672595.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(3428..3583)
                     /locus_tag="ACF3UF_002535"
     CDS             complement(3428..3583)
                     /locus_tag="ACF3UF_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672596.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFILKKN"
     gene            complement(4042..4299)
                     /locus_tag="ACF3UF_002536"
     CDS             complement(4042..4299)
                     /locus_tag="ACF3UF_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFD3672597.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(4292..4561)
                     /locus_tag="ACF3UF_002537"
     CDS             complement(4292..4561)
                     /locus_tag="ACF3UF_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3672598.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(4692..4871)
                     /locus_tag="ACF3UF_002538"
     CDS             complement(4692..4871)
                     /locus_tag="ACF3UF_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672599.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(4887..5087)
                     /locus_tag="ACF3UF_002539"
     CDS             complement(4887..5087)
                     /locus_tag="ACF3UF_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672600.1"
                     /translation="MNKIIPLLFVLFVGEILMRHGAALHLNFVVFLGILVFCLIFWRF
                     VLTLVSLIFKLIAAIFLIGLFR"
     gene            complement(5252..5959)
                     /locus_tag="ACF3UF_002540"
     CDS             complement(5252..5959)
                     /locus_tag="ACF3UF_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672601.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
     gene            complement(5952..6389)
                     /locus_tag="ACF3UF_002541"
     CDS             complement(5952..6389)
                     /locus_tag="ACF3UF_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672602.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
BASE COUNT         2001 a         1192 c          908 g         2333 t
ORIGIN      
        1 taatattaac aaatgaataa aatccttaca acatttgaga ataagttatc agtagacact
       61 tacaaaaaat tctcatacta ttgtcacttt tctagataaa tggcaaaaat tttcagcatt
      121 aaatgacaaa aactaatgag aatttgtctt tccatttttc tcctccattt ttgccaaata
      181 acgataaatg gtggttcttg agacgttcca ccgttccgca atagtcttaa taggtgtacc
      241 gctatccact aaagtcttca gtaattccaa atcttgttca gacaattttt caggacgacc
      301 accaaaccgt cctcttgcac gagcagctgc tcgtcctgct gcggatcgtt ccaggatcaa
      361 attacgctca aattctgcaa atgccgcaaa caaatgaaac atgagctgtc ctgtagaact
      421 tgatttgtcc atcgtaatat tttcttgaat actatgaaaa ctcacaccac gctcattcag
      481 tcgattgacg attgaaatca aatcttccat atttctacct aaacgatcta agcgccaaac
      541 gacaagtgta tcgccagagc gaacaaaatc aatggccatt tctaatcctg gtcgattact
      601 ttttgcccca ctcatatgat cagtaaaaat tttttcacaa ccaaatttat ttaggctgtc
      661 ttcttgtaaa tccaaatttt gtaaaccagt agatacccgg gcgtatccta ttttcaaaaa
      721 aatcactcct tcattaattt tattgtaaca taactttatc catatagttt aactgaacat
      781 agatattgtt atgggtttat gaacatgaaa tgaattgttt ttttgaaaaa taaagcaaaa
      841 aaagaaagtg tccagaaatg ggtgatttta tgaacacttt caattagaaa aaaagaatgt
      901 cgactagaca ctcttttttt aaaatcatta tttttctttt tgatatgttt tttggtctct
      961 tttttttctt ttttcttcag aatcttctag attagaaatt gatttttgaa ttttttgtgt
     1021 ctcctgtaaa gttcgctgaa cttgtaaagc tgattcttct ttcggtaaat taattttact
     1081 tagaatatcg ctatcttgat aaaaatttgg tgtgttcaca aattctggca taaaaaatcc
     1141 ctactttcta gttaaggttc ctgaataagt cgcaatccaa ttgtttccag ctgatttata
     1201 actttgtaaa tacaattttc catagtacca ataaccattt cttttttctt tccaattccg
     1261 tgattgagga ggtctagaag gccaaccaac tttatcaaaa atcatcgttc ctgtcactcg
     1321 tatcgtttta gaagctgcta gagcaagtaa tggagaaact attaaataat tttcagtaac
     1381 agttaagtcg ttagttgggt taccaatggc tattccgtcc ctatctaaag gagttaattc
     1441 ttggttatta tctactacag tagttggttc atttgtacta tcagcaaatg taggaattgt
     1501 agttccagtt acactaattc caatagttaa aatacctaaa gataaaataa acttattttt
     1561 cattgtctat cacctcgaaa tcaaaactaa gaaaacgttt tcttaataaa tcttaacaga
     1621 taaatcaagt tatatactag aaaattcata aaatatattt ttaatgtcat aatcgtttaa
     1681 attttcttga ttgacattta tttacaaaaa atattgccat ttaaaaagaa aagtgacata
     1741 tggcttcctc gtgtatgatt agggtgtatt ttaaatagtt gcagaaagta ggtaaaagtt
     1801 ttgagagttg catacatacg tgtctcatcg atcgatcaaa atgaacaacg ccagattgaa
     1861 gaaatgaaaa aattcggtgc agagagaatt ttcatcgaga aacaatctgg cgcaacgatt
     1921 actcatcgac ctgttttcca agaagcatta gattacgtcc gagatcaaga tatttttatt
     1981 gtggaagcta ttgatcgact tggaagaaat tatgacgaga tcatcgcttc agtcaattac
     2041 ttgaagaaga aaaatgtgaa gctgatcatt actagtttac cgatcatggc tgaagcaatt
     2101 ggcaatcctc tcctggataa attcattaag gatctgatca tccaaatttt ggccatgatc
     2161 gctgaacaag aacggactga atcgaaacgt cgccaggcac aaggaattaa gatcgcaaaa
     2221 gcaaacggcg tctacaaagg gcggcccaaa ttatacagtg cagacgcaaa agatccccaa
     2281 cgtcgccttg tttacaaaag catcgttgaa gatcttaaaa atggtgttgc gattgctaag
     2341 attgctaaag actacaatgt tacgagacaa accgtgtata gaataaaaaa agacagcatg
     2401 gtcaatgaca aatagttgat catgctgctt ttattatctt ctcatcttta atttcctaca
     2461 tataattact atctataaaa ttaagtctta ctcagaacag ataaagcata aaattccaac
     2521 aaaccatttt ttacttaact aaataaagag tctgttaata taatcttcac ttatttacgt
     2581 taatccccta ctgtatttgt tggttcctta tctatatttt ctacaaaatc cttattatct
     2641 tgtgatttag cttcgtataa ttctttgtat gtcgacacat tggttatact aattcctata
     2701 gctagttctt gagactctac ttttctctct agctcctttg acaaagtgat ttgagattta
     2761 tttggttccg ttggagtcaa ttctatagat tcttcataaa aatctctata cataaagcta
     2821 tcattaattt tataaaaaaa attaaatgtt tttagcactg ccatataaca ttcaaaacat
     2881 tcttctatag ttggtttact tccttgagga gaatgaacca atttattacg tttttctatg
     2941 aaatttttaa tttcctttct tatttctttc ggaaactcaa tattaaagta ccctttaaac
     3001 atgctcccta ataatttgtc tacaggggga gattgtaaat tctcaaatat tagagttaaa
     3061 tcaggtttct cttgttgata aaattccttt acccctattt cacaggctgt aattatcgaa
     3121 ataaacctat ctctagtatt tgatatattt ttacttcttt taaggagtat aagagaaaag
     3181 gggatacttt cgtgtccatg catgtaatta actaattgtt gagcttcaga agttatatct
     3241 ctaattatat agttaacgga attaggaagt gtctttaact ctaatgaaat ttctatccaa
     3301 ttactatctt ctaatctgta tatgctcgaa gtataatttg attcgtcagc aagcatcgct
     3361 acatcccaaa cactgatcat aaaatctttt aaacgttcaa tcatttcagc aatattgcta
     3421 aaatcagcta atttttcttt agaataaaaa aaacatttat atcagaatca ataaattcta
     3481 ttttttttat tactatatcg tcatcattat cttgaccatt tatgtttatt gttccctgag
     3541 tggggagtac ttctttcaaa ttcaagttaa atttatattc cattacttct cctccaatat
     3601 ataaaaatta cttaactgta tccaaattta atatgtaaat aaatcattaa tttttagcta
     3661 aattctatga gaagtttatt tttgttgttt ttgctaatta actaaaacta gtacaaaaaa
     3721 tttaaaatag attattaaac ctattgctta ttctattcag tcatatatat aagcgtcatc
     3781 ctttagtaac taacatccca cactacaata gtattataac atatctattc aacttcaaat
     3841 tgttgaaatt taagccattt atatttactt ttcctcaact ttagaaatga ttttactaac
     3901 cttatatccg taatacgcgt aacaaacaca ttcattaata acaatcaaca ctaagctata
     3961 ttagcttttt aaatgactag ggtaaataaa ataaggatca aaaactttta agtttctgac
     4021 cctttcctta cttccgattg gttaatagtg atcttttgca gaataaataa atatcgtttc
     4081 attttcaact ctatatatca gtctatgttc atctgtaatt cttctggacc attttccaga
     4141 taaatcatgc tttaatggct caggttttcc taatccagca aagggggaac gatcgatatc
     4201 ttttattaac ttgttaatct tttttatatt gcttttgttt ccttgctcat gccaataaag
     4261 ataatcatcc caagcatcat cagaccaagc cttaatcatc agattcaacc tcgattaagt
     4321 catgtgtttt aaatgcacct ttggagaatt gttcatctcc tcgacgaatt ttttccatga
     4381 cgtaattatt agaaagtgtt ctcaacgttt cttgcataga atcataatct ctttttgata
     4441 atacaacaac tgtatcttct acatctttac ttgttacaat aagtgtttca gcatcctcat
     4501 taacttgttt catataacta cgtaaatttt ggcggaaatt tgaataagct actgcttcca
     4561 ttcctttcac cccttattta tttctataaa acaattgtac attatattgt acaattaagc
     4621 aaatgattaa tattctaact tcttataatt aaaagtgcta tcacttttag tttttaggat
     4681 aaaaagtgac gtcacttttt gagtgctggt acctcaaatc ctgctttttc ttgggcaatc
     4741 aataaatcta acgcaataca cataatcctg gattcacttt tgccgtactt ctgctttagt
     4801 tgctgcaatt ctttttgtct cttttcatcc aacgtcacgg gtaaccgttt atttcctatt
     4861 gcaattggca ttagtactct ctcctttcat cgaaataacc ctattaaaaa tatggctgca
     4921 atcaacttga atattagact cacaagggtt aacacaaagc gccaaaagat caaacaaaat
     4981 accagtattc ctaagaatac tacgaagttt aaatgtagag ctgcaccatg acgcataagt
     5041 atctcgccaa caaacagtac gaacaataga ggaatgattt tattcatatg gatctccttc
     5101 tttctcttag gttatcgggc tttgcccgct tatttcgcac cacctaagcg gcgggggcgg
     5161 ttggatcgat tggtgcgaaa taagaaccat tcccttaatt tcaaggtttt ttgttcttat
     5221 ttcacacatc ctcacttttc ggtataaatg gttattgacc ttttttcctt tcaaatcgtt
     5281 gatatggcat tcgtttacgg tcaagttcat tttggatttc ttctgtatcg tcgtaagtgt
     5341 aggtgtctaa aaaatcagtt aaagtcgtgt accagtcgtc gcctgggtta tctacttctt
     5401 ctacatattc cctcaaaaat gcttcgggta cagtgagttc ataatccatt cccattaaca
     5461 cgatagattc cgtcccacac gtcaaaaatc tagtaaatac aaggtaataa tcgtctaccg
     5521 tcgcatcttt gctgtttagc tcttccattt cttcttccat taattccatg ctctcaaaaa
     5581 ttgaataata ttctgattct gagtaatagt gtttcctgca aatcgtgtag ctgacaaagt
     5641 tttcgaccag ctcactcctt tctaggtaaa cattcatgat atatttttct gtttctagtc
     5701 gtagaagctc cgctcctttt tttaatgtgt caggacgacg tttatacacg tctaaacgat
     5761 tatggctgac tgtaaccttc gtttgactcg tttcactttc catatacaac tgttcttcca
     5821 ctctttgaat aaagtacttc atttcttcca tacaactaaa gtctttttga atccgtctga
     5881 ttacttcatt caagtgttct ttgtttgtta aaaattgcga aacatcttct gttgttagct
     5941 gataaaccac cttattcatt atctttctcc tccgattcaa tcgtataaaa tgcaccattt
     6001 ttttcgatat tttcaaaagt atctagccag tcgctagcca ttgctttagc tttcttaatc
     6061 tgtgcgaatt ttgcataagt cagttctaag gcttgatatt cggaaggttt gatagtgctt
     6121 ggtttgacac ctacttccaa gcatagtaag gcttggaaaa accattttcc attttgtttt
     6181 ttcagttctt ccagtgttcg atagtacgtc gcaatgagat tcatttcgac acctgattca
     6241 atcatttctt ccactgcgac tgacaatttt tccttgtaat gttttttggg tacacgtgtt
     6301 tcatggtata ggaacgtcat atcctccatt ttttgtgcca ttttatccaa aggtaatttg
     6361 acaaattcgt catagtaatt ttgagccata ttttttctcc tttttagttc tctaatttgg
     6421 ttaaccaata ttcg
//
LOCUS       DAXLPY010000106         6188 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.108, whole genome shotgun sequence.
ACCESSION   DAXLPY010000106 DAXLPY010000000
VERSION     DAXLPY010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.108"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            725..811
                     /locus_tag="ACF3UF_002542"
     CDS             725..811
                     /locus_tag="ACF3UF_002542"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFD3672603.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACF3UF_002543"
     CDS             complement(932..1621)
                     /locus_tag="ACF3UF_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672604.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="ACF3UF_002544"
     CDS             complement(1628..1906)
                     /locus_tag="ACF3UF_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672605.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="ACF3UF_002545"
     CDS             complement(1866..2780)
                     /locus_tag="ACF3UF_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFD3672606.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACF3UF_002546"
     CDS             complement(2762..3142)
                     /locus_tag="ACF3UF_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFD3672607.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACF3UF_002547"
     CDS             complement(3592..3879)
                     /locus_tag="ACF3UF_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD3672608.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACF3UF_002548"
     CDS             complement(3899..4123)
                     /locus_tag="ACF3UF_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFD3672609.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4593..4763)
                     /locus_tag="ACF3UF_002549"
     CDS             complement(4593..4763)
                     /locus_tag="ACF3UF_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672610.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4778..5311)
                     /locus_tag="ACF3UF_002550"
     CDS             complement(4778..5311)
                     /locus_tag="ACF3UF_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFD3672611.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5332..>6188)
                     /locus_tag="ACF3UF_002551"
     CDS             complement(5332..>6188)
                     /locus_tag="ACF3UF_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFD3672612.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1640 a         1152 c         1042 g         2354 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatttattat ataacaatga ttaacgtcat aaaaagtagt tttgaattca
     4261 taatcgttta aataaaatta taagatcagt tatttaaaca gctagtagac ataatgtgta
     4321 tactaccaag taacgcctgt accaagggat ccaggcgctg attttgtgaa tttttattgg
     4381 tctaggttaa aagctctttt taaggcttgg ttttctgcgg ttgtttcttt ctaattcttt
     4441 gtgaatattg atcggtcatt ttttaaatac ttgttatttt tgtttgtgtt tgttatgctt
     4501 tttacatatc tcatattcat ttattattct tttctaaggt taataatagg ataatctctt
     4561 tcagaaagac tgctcgtacg agcagtcttt tcttatttat caagtttttc tacaaatact
     4621 tcctcatttt gactgttgta gtaattagga ttgagtttta gttccccttt tttatttcct
     4681 ttgttggcca ctgataataa cattgggcta aagcttaata ttcctagtag gatagaaccg
     4741 aatagcaagt gtttttttgt cataagtatt tccttcttca tttccatagc tgccaccatt
     4801 ttttccaatt ctttgtttgt tcgtccattg tttctgttgc ttcagaaaga gtcgttgaac
     4861 tattctctga agactcttcc gtataagtca actgcagttg ctcctgaagt ttttcgattt
     4921 gttggttggc ttgcagggtg agttgttgtt gctggtcgag tagtttttgt atatgagaat
     4981 tattttgctc tttgagggca agttgttctc gtaaaaattc attttcttca cgcaactgat
     5041 ctagcaactt gtttgcaacc acgtttttgt ttggtatata agcattttta tcgttgtttt
     5101 gttcatgttt atgcaactta tctagcaacc tttgattgtc taagttgcga gcaagttgca
     5161 atactccaga acgcaataca accttataac cacgctcatt tttagctatc atggaagaat
     5221 ctaatttttg gatatgtttc gatattgctt gcctactcat cttaaaaaga tctgacaatt
     5281 cctttattgt aaaggtttct tgtggttgca tactggttgc ctcctaggtt gctactggaa
     5341 taaattatct aaatcagata ataaactttt tttctctttt tccgaaagtg cggactctgt
     5401 ttgtttttca agagcttttt tctctttttc tagttgtttg atttgttgga ggagttcaag
     5461 ttctcgtttc ttctgtttga ttttttcgtt aattgttgta gcgggttctt cgtattcttt
     5521 ttgtttatca gctaaagcca atgctttatt ttggtcttct ttggttggtg catgtttgtt
     5581 aaagtcgtct gcttttttga tctcaggttt gaacgtaaat tgatagccaa taacaggttt
     5641 tccccgtcct tttccgtatt tctttttgat tgttagtcct ttgaagattg cagttagttc
     5701 ttgacgtata ggttttataa ctcgtttatc tatatcaggt tgcttataac ttttaggaat
     5761 atctaataat tcaagaaagt cttctttgga gaaatatgcg aaacctttgg ttctgtattg
     5821 ctttaacaga cgaaacatag tctttgcata gccactttgt agctcgttga attgttgtaa
     5881 agaatagcgt acccactcgt ctaaattatt taacaaaggc agtgcttttt cgtaaattcg
     5941 tatatctacg taaggatttt ctacgtcccc gttgatttta aattctgtaa acattacaaa
     6001 catatcgtaa gaaagcccag actcacttct acgaccaaag cgtaaagata agattttttc
     6061 ataagttgct tttaaatctt ctacaaatcg tacatttgca gttgctttgt agttacttaa
     6121 atcttttagt tggtcaaacg taaaacgaac tgtcttatcc cctttttcac gcattctaga
     6181 cacgatgg
//
LOCUS       DAXLPY010000107         6127 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.109, whole genome shotgun sequence.
ACCESSION   DAXLPY010000107 DAXLPY010000000
VERSION     DAXLPY010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.109"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            352..1041
                     /locus_tag="ACF3UF_002552"
     CDS             352..1041
                     /locus_tag="ACF3UF_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3672613.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="ACF3UF_002553"
     CDS             1028..2236
                     /locus_tag="ACF3UF_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFD3672614.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="ACF3UF_002554"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="ACF3UF_002554"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFD3672615.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="ACF3UF_002555"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="ACF3UF_002555"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFD3672616.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
BASE COUNT         1878 a         1154 c         1193 g         1902 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgtggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtgtattaaa agagattgta aaaaagctgt cctgcatcaa
     6001 gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta
     6061 ccgcagatgc aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt
     6121 tcgagta
//
LOCUS       DAXLPY010000108         5965 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.110, whole genome shotgun sequence.
ACCESSION   DAXLPY010000108 DAXLPY010000000
VERSION     DAXLPY010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.110"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..1383
                     /locus_tag="ACF3UF_002556"
     CDS             <1..1383
                     /locus_tag="ACF3UF_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFD3672617.1"
                     /translation="LCGQFYVNKEVNLEKLSNLLHVCKTTLLNDINNIKKEFEEQIAY
                     THREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDEPDYLQLTECEFISVS
                     KAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRLGGFNSWELPESFFER
                     ADRFIESVTENSGRFYDKENKEILLIGFAISFLRQQVCAVTIDSKFIEEIKKRPIYNY
                     VESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIK
                     ELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQ
                     TIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYIVTNSDVHYLIYREAL
                     EAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDAVQYENIIPISINTID
                     RAIISAVQNK"
     gene            complement(1475..1840)
                     /locus_tag="ACF3UF_002557"
     CDS             complement(1475..1840)
                     /locus_tag="ACF3UF_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFD3672618.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1837..2202)
                     /locus_tag="ACF3UF_002558"
     CDS             complement(1837..2202)
                     /locus_tag="ACF3UF_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFD3672619.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2394..2642)
                     /locus_tag="ACF3UF_002559"
     CDS             complement(2394..2642)
                     /locus_tag="ACF3UF_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672620.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2641..2769
                     /locus_tag="ACF3UF_002560"
     CDS             2641..2769
                     /locus_tag="ACF3UF_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFD3672621.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2826..4520
                     /locus_tag="ACF3UF_002561"
     CDS             2826..4520
                     /locus_tag="ACF3UF_002561"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFD3672622.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4620..4793
                     /locus_tag="ACF3UF_002562"
     CDS             4620..4793
                     /locus_tag="ACF3UF_002562"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672623.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKVV"
     gene            5171..>5965
                     /locus_tag="ACF3UF_002563"
     CDS             5171..>5965
                     /locus_tag="ACF3UF_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFD3672624.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEK"
BASE COUNT         1955 a         1133 c         1090 g         1787 t
ORIGIN      
        1 ttatgtgggc aattctatgt aaataaagaa gtcaatctag aaaagctctc caatctcctg
       61 catgtttgca aaaccacttt gctcaatgat atcaataaca taaaaaaaga atttgaagaa
      121 cagatcgctt atacacatcg ggaaaaggac cgttacactt tatatttttc agaacatata
      181 cctcgatgca agatcatgca gcaattgtct caaaattcgt tgtttttaaa aacttgtctg
      241 ctttatttgg aagaagatga acctgattat cttcaattaa ctgaatgtga attcatctct
      301 gtcagcaaag cttattcatt aaaaaaacaa gtattagctt attttaatga ctgcgggatc
      361 gaaatcgacc gctactcccc tcgattcact gaaatggaaa gacgtctgct gcttcttaat
      421 gtgtcgtatc gtttaggcgg ttttaattct tgggagctac ctgaatcgtt ttttgaacgt
      481 gccgatcgtt tcattgaatc cgtaacggaa aatagtggca gattttatga taaagaaaat
      541 aaagaaatct tattgattgg ttttgctatc agtttcctac gccagcaagt gtgtgctgtg
      601 acaatagatt caaaatttat cgaagaaatc aaaaaacgtc ctatttacaa ttatgtcgaa
      661 tcagcatggg aaaacactga tttccaaacc tattataaaa aagaagaatt cgcctttatt
      721 ttgacactat tcaatctttg taattatggt ttccattctt atcagttgat tgcggaagac
      781 tttcaacagc tacaccaagt gtttattgac aatactcccg aaataaaaga actagttgct
      841 acctttgaat ctcacttcaa tcaagaatta ttcggaaacc aaccattcga acgtgcgctg
      901 attcatctga tgcgttcggc ttgggataac tatcaattat tcatgccaga aaaattttat
      961 cttctaaatg aggaacagac aaatttatat aaagaagtcc agacaatttt ttccagctgg
     1021 tccagccagt taccttatga tctacggttg aatcctaatt gcatgcgggc ttttgtgatc
     1081 gaattgagcg gaattctccg tctgacaaaa gaacatctga ctatctatat cgtcacaaat
     1141 tcggatgttc attatctgat ttatcgggaa gccttggaag ctgtaactac tttcgatttt
     1201 caagttgcac caacaattta ttcaagtata tctgatataa agaagtatgc gcagcagtcc
     1261 tcaaaccggg tattatgtga acgtacatta tatacaccag atgcggtcca atatgaaaat
     1321 attattccta tttcgatcaa tacgatcgat cgagctatca tttcagctgt gcaaaacaaa
     1381 taagggactg tgacaaaaat catgtcacag cctcttattt gttgaagatg cccatttctg
     1441 taacaatctc ttgatacaca tcaggctcac aacctcactt attttggaca tctacgggtc
     1501 cgatctcttt atttaaaaaa taagaaatga tggttcggat aactaccaac gccgctagtt
     1561 ggaaaatatc ctgcaaggta ggtttgataa tcgattcgat gatcccagct gaaacaagaa
     1621 tttccaaact tagaagtata tagcctccca acatcttttt aatagcattg ttctcgctga
     1681 ctcggtcgct ttgcactttt gtatggacaa ataaatattt caaaaaatcc ttgattgata
     1741 gacaaacacc ccaaaccaat aaacagatag caaagatatc aagtcccagt acaagttttt
     1801 caaaatatgg aagaagaaac tgcatcaact ctgtcgtcat cctacctctc ctcttctttg
     1861 tttttctttg tcttctattt cctgattcaa gaaataagaa atgactgttc gaatgataat
     1921 aataagtgca agcttcaaaa tatctgtcca agtcggcttg ataactgact cgatgatatc
     1981 agcaacgact agtacttcca agcttaacaa aatataactt gctagcagtt ttcttgtatc
     2041 tgcattacga gtattacgtt ctgcatagtt tttcttgaca tgagaccaat caaaaagttt
     2101 gaatagaaca agaacgatcc cgacaattaa gataccgata gaacaaatat ttaaaatagc
     2161 aatgatccat tctagaaatt caattaaatt tgagcgaaac atatacgcta cctactttct
     2221 tttaatttgt tcctattctt ttattgtaaa agaaagttac cttgttcgtc tatttaaaag
     2281 ttgttctaat gataacggtt cgcttaaatt tttctttttc actctcccct ttttctccct
     2341 ccatccataa atcgtggaag tatccaaaac aacgtagcaa gttaaaataa ggcttagtcc
     2401 gtcatcagct tttcaaagaa gcactgtctc ggtgcttttt ttgtacccaa atttctaaaa
     2461 atagaaccat acacctcctc aaatcttttc ttcttaccta ccctattttt atttacagga
     2521 aaatcagaca cttcttcttt tttgtcaaaa tttccttttt cttctcgtcc tatcatttgg
     2581 cattctaata aaaacgaact atccttggat atagaaagag aaaacaagga ggcgtttttc
     2641 atgagtaaaa aattaatcaa agtcggcatc ggtttaggtt tgcttgccct tggcgctgca
     2701 tatctaggaa aaaagacagg actattcgaa gatgacagtc atttatatga tgaattcgaa
     2761 tcaatctagc atcctattta gttgaatcac tacggacata cttggaagac attggaggaa
     2821 tcacaatgag aaaaagtaaa gcaataatga ttggtgccgg tattgccaat atggcagcgg
     2881 ctgtttattt gattcaagaa ggcaaatgga aaggggatca gatcaccttt tattcattgg
     2941 atgatcacgg ttcaaatgat ggtgcaccga ccgacactgt agtggatgaa tattggaata
     3001 aaaaccatcc attagaaaac caaaaaggct atattgctcg aggcggtcgc atgcttaatt
     3061 accgtaccta tgtagatttg atggatctgt taagtcgaat accttctgtt actgagccag
     3121 ggatgactgc tgaagaagat acgagagatt ttgatgcaaa acaccgaacc tttgacaaag
     3181 cacgtttgat ggaaggtggc aaaggaatca ttgatggcgg aaaactggga ttcaataata
     3241 aagaccgtat tcttctgact aaactgattg ctatgcctga ttcagaagaa gaaaaactag
     3301 acaatatcac tatcgaagaa tatttcaaag atgatccaca cttttttgaa acaaacttct
     3361 ggtttatgtg ggaaacaaca tttgctttca gaacacgtag ttctgctcaa gaattgcgtc
     3421 gctatatgca tcaaatgatt tatgaattca ctcaaatcga acatctagtg ggcgtcaatc
     3481 gaacacgtta caatcaatac gaaagtatta tgcttccttt gatcgagtac ttgaaagaac
     3541 aaggatgcaa aatcattttg aaccgccgtg tcactgactg ggaattcaaa gaaacaccga
     3601 tgcaagatga aatcactgtg actggtttga aaatgaccaa tacactgact caagaagaag
     3661 aacacgttgt ggtcgatgaa gatacagcag ttattttcac taatgggtcc attacagatt
     3721 cagctacttt aggagattac gaaacaccag ctgtagaaaa tatggattat ggtgcagctt
     3781 ctagtctctg gaaaaaagcc agtgaacgtt tctacaactt gggaaatcct gacaaattct
     3841 ttgctgatcg agatgcaagc gaatgggtca gctttaccct gacgacgaaa aaccatttgt
     3901 tgttgaatga aatcacccgt atcacgactc aagaaccagg aaatgccttg aattcattta
     3961 tttcaaccac accgatcacg ccgttaggcc aaaaagatgt caatatgtct atcgtcgtgc
     4021 atcatcaacc gcattttacg tctcagaaac caaatgaaac agttatttgg ggttatttcc
     4081 tttatccaag acgacgtggc gaatttgtgg ataaacagta tattaaaatg aatggaaaag
     4141 aaatgctaga agaactgatt ggacaacttt caaaagtaga tcctggacca gtgaatattc
     4201 gtgaaaaaga aacagaaatt ttcgacagcg taataaataa tatccctgtc tatatgcctt
     4261 atgcttccgc gttgttcaat aatcgtgcca aaagcgatcg accaaaagtc attcctaaac
     4321 attcgaccaa tctggccttt acaggagaat ttgtcgagca gccttatcag atgatcttta
     4381 ctgaacaaag tgctgtacgt tctggagaaa tcgctgcttt ccattttgcg ggtatcccta
     4441 tgtcacgtct tgtcaaaaca ccgcgttacg acaaagatat tcctactcta gctcgtgccg
     4501 caaaaaaaat gtttgaataa tcaagaggtt gtgaaaaagc tgccctgcat caagtaataa
     4561 gaacaaccag gctaaaacag cttcttatgt ttttgatttg gttggactta ttaccgcaga
     4621 tgcaagcttt tgaacaccgt ttaccaagag gttgtgaaaa agctgccctg catcaagtaa
     4681 taagagcagc caagctaaaa cagcttctta tgtttttgac ttggttggac ttattaccgc
     4741 agatgcaagc ttttgaacac cgtttaccaa gaggttatga aaaagtcgtt tagtttcgag
     4801 tatgaagaaa aattttgtga aaatggttcc tcacgttttt gcataaattt gacttaatac
     4861 cgagaaactg atcccttctg tcataacctc tttttattta tgtctgtttc tttttgaaaa
     4921 caaccatttt ttcaacgttt actctcttgc caatccaaca tcatctaaca gatacaacta
     4981 tttcaatgat taccattaca ctaaaaaatc ggaaactcac ctctccgaac acaaatacat
     5041 aagactatag aatgtttcat ttaagaaaaa aagcgtttca ttatcaaaaa ggtaagatct
     5101 cctttaaaat gaaattatct gtagtactaa taatgcagac aattttatga atctgaaagg
     5161 agcatctcca atgaaagcag tcacttggca aggaaaacag aaaatggaaa tcagaaacgt
     5221 agatgatcca aaaatattag aaccaacaga tgcaatcatc cgtatcacag caacagccat
     5281 ttgcggctcc gatctgcatc tttaccatca tggtgaagca gttttggaaa aagggtatgt
     5341 tgtaggacac gaaccaatgg gaatcgttga agaagtggga tctcaagttc aaacattgaa
     5401 aaaagggcaa cgtgtggtta tcccttttaa tattagttgt ggtcattgtc atttctgcct
     5461 gaatcacatg gaaagccaat gtgatgaatc aaatccagat cagttatatg gcgggctttt
     5521 cggatttggc aagttgaacg gtaatcattg gggtggtcaa gcggaatatc taagagttcc
     5581 ttatgcagac tctacttcat ttgttgtacc agataatgat cttcctgatg aaaaagtttt
     5641 atttctatca gatattttgc ccacagctta ttggagcgtt gaaaacgcag gagtaaaaaa
     5701 aggcgataca gttgtgattc taggttctgg tccagtcggt ctattcgctc aaaaattcgc
     5761 tgttatggct ggagcagagc gcgtaatcgc agtagatcca gtacagcacc gtctagataa
     5821 agcggctaat tacaatgggg ttgaaactta tttcttagaa gacacggcac aagctggaac
     5881 agaattgtat gaactggcta aaggtggcgc agatgtcatt atcgattgtg taggaatgga
     5941 cggattagag cctgtcaaag aaaaa
//
LOCUS       DAXLPY010000109         5952 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.111, whole genome shotgun sequence.
ACCESSION   DAXLPY010000109 DAXLPY010000000
VERSION     DAXLPY010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.111"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(289..2955)
                     /locus_tag="ACF3UF_002564"
     CDS             complement(289..2955)
                     /locus_tag="ACF3UF_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3672625.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            3297..4748
                     /gene="cls"
                     /locus_tag="ACF3UF_002565"
     CDS             3297..4748
                     /gene="cls"
                     /locus_tag="ACF3UF_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFD3672626.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            complement(4953..5768)
                     /gene="thiD"
                     /locus_tag="ACF3UF_002566"
     CDS             complement(4953..5768)
                     /gene="thiD"
                     /locus_tag="ACF3UF_002566"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFD3672627.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         1708 a         1283 c         1055 g         1906 t
ORIGIN      
        1 tcttttgatg aataataaaa tgattggctt tccgtctatc ataaataaaa aaagggactg
       61 tgaccaaagt cgtgtcaaag tccctctttc cgaataaaca gtgtccaatc agatgaccct
      121 cagtattagc tcaaaatgct gattttacaa cttcttcctt aaacggtgtt ctcctgccaa
      181 ctcttcggtc acaagtcaca atattcaaca aacatgagaa gctgtttgtt gaaattgcac
      241 cttgtgactc agaattaaac ggcaggctca caacctcgtt gattcgtttt atttatttcc
      301 ttgtactcgt acaatgatca atttagtgat ttccatcaaa acaattgtca caagtgcgat
      361 tcccatacat gtaaagactt ctgtcaatcc aaatgctgat gggatagaga agacttcttt
      421 cagtcctggg atcattgtta agcagtaaag cgcgctacat acaactacag ctagtaagac
      481 acttctgtta gagaagaacc ctgcttggat agctgtttgt gtgtttgaac gtgctgggaa
      541 tgtttgcaat gtccgacacc aaatcaatgt tgaaaatgac atggctacac cgaattcagg
      601 tgaatgctgc atgccaagcc attgagcaaa gataacagca atcccaatca gcacaccacg
      661 atacgttaca gaaatcaatg ttttgtccgt aaagattcct gaatttggat ctcttggcgg
      721 gcggttcatc gtagcaggtt cagctttttc tgtacctaat gcaattgctg gcagtgaatc
      781 attgactaaa ttgatgaaca acagttgtaa tgctgtaaat ggattggacc agtcagcaac
      841 taaggcaaag atgatcgcaa tgatcgcacc taaatttcct gcaaatagat aagaaatagc
      901 tttcttgata ttatcaaaca cattacgtcc tacttctact gcgctgacaa tagaagcaaa
      961 gttatcatcc gtcaatacca tcgctgctgc atcttttgcc acatctgtac ccgttcccat
     1021 agcaattccg atgtctgctt gtttcaatgc tggtgcgtca tttacaccat cacctgtcat
     1081 agctgagata tgacctttat tttgccaagc acgaacgata cgaattttat tctcaggtga
     1141 aacacgtgca taaacagtga ctttttctaa aacttcgttt agttgatctt ctgtcaattc
     1201 atctagttcc gtcccggtca aagccaggtt tccttcttca aaaatcccga tttgttttgc
     1261 gatagcaaca gctgttgttt tgtggtcacc agtaatcatg attgttttga ttcctgcact
     1321 tcttgcttct gttaccgcct gagtcacttc agcacgtgga ggatcgatca tagcaagcaa
     1381 accaacaagg atcaaatcgt cttcatcttc aaatgataaa tcaaaattat caagtggacg
     1441 gtaagcaaaa gctagtacac gtaatgcgcg tgttgaaaaa gcttcatttt gctcttggaa
     1501 ttttttcatc aattcatccg tcatcggaac gacttcacca tttagcaata cttttttact
     1561 gcgttggaag acgatatctg gtccgccttt gacaaacaag taattttcgt tatcgatcgt
     1621 gtgtccagta gacattaatt ttcgatcaga atcgaaagga agttctgctt gtcttgggta
     1681 gttgtttcgg atttcctgat aaggctggtt taatttttca ctaaagtcga taaacgctac
     1741 ttccgtaggg tcgcccaatt tagtaccgtc ttcactgatc gatgcatcat tcgctaaaac
     1801 actgatttcg atcaagcgac gttcgtcagc tgtccatttt gaagggtcat ttgtgaaatc
     1861 cccagtatcg ccattaccta aaaagtagtc aacaactgtc attttgtttt gtgtcaatgt
     1921 accagtctta tctgtacaga tgatacttgt cgaaccaagt gtttcaactg ctggaagctt
     1981 ccgaataatg gcatgacgtt ttgccatttt attcgttccc aaagataaca cgattgttac
     2041 gatagactgt aatgcttctg gaatagcagc tacggctacg gctacggcaa acatcactgc
     2101 gctgacgata tctgcagtca tatctcctgt accttctcca agataaatac gaaacagttg
     2161 gatacctaaa atcaataaag acaatgccaa aatagccaga cttagttttt tactgaattt
     2221 atccagacct cgttgtaacg gagtgacttg ctcagttgtt gattccaaaa ggccagcaac
     2281 ttgtccgatc tccgtattat tcccagttga agtcactaag aatttaccgc gtccgtaagt
     2341 tacgatcgtt ccactgaata ccatatttgt acgatctccg attggtaccg tacttgtgat
     2401 atccgttact tctttttctg cagaagtcga ctctcctgtc agcatacctt catctacttt
     2461 taatgatccc gcatctagta aacgtccatc agcaggtaca taatcgcctg cgtctaacaa
     2521 cacgatatct cctaccacaa gttcgtttgc cggaatcgtt ttttccttac catcacgaat
     2581 cactcgagca tcgggcgctg aaaggttttt caacgcttct aaagaacctt ctgctttttt
     2641 tgtttggaca acactgatta tagaattcaa catcaatact gcaaaaataa ctaagaattc
     2701 gatgtagtca cccatgacca tctgaatcag tgcgacaatc agcaatacga taaccattgc
     2761 atctttgaaa gtttctaaga acaatttcca agttggcttc ttcggctttt cttttagctg
     2821 gttcaagcca tctctttcta atttttcctt cgcttgcgtg gtgctcaatc catcggttga
     2881 gctctgcgtt tgctgcatca acgagtcgat cgtttcttta tagaccgctt gttgtgcttg
     2941 ttccttgttt tccaaatttc atcccccatt ttttgatctt ggccctagtc ctgtctgaaa
     3001 aaaaaagaga cctaagacaa atacgcattt gtcttaggtc tcaccatttc atacaatacc
     3061 agaaaaccat ttggttaact tactgttgat attatcgcaa caaacgttgc cggttactcc
     3121 cctaaggaga tattcaactg tactaatatc ctaccttatt aacctacaaa aagcaactac
     3181 tttagcccga tttacctaca ttttcatgaa aggagtgaaa agtatattca ccttggtagg
     3241 cttctttctt ctatcatgct atactaatgt tattgtatgt aaggaggaac atttttgtgg
     3301 tatctagtat tataaccgcc ctttatctat taaatgcact tattgctttg gtggctattt
     3361 tgatcaaacc ccgagatgta gcagccattt gggcatggct cttagtattg tttgcccttc
     3421 ctggggtggg ctttgtatta tatttatttt tcggacgtgg attaacggat aagaaaaaat
     3481 tctatctccg acaaagtgac ttgaaagaat tagaaaactt tcagtctttt agaggagata
     3541 ccattgaaca ttacgatcct gacatgggcg ataaagacaa acagcaattt gtcgacttct
     3601 tctcttcatt aaatcgtatg ccgctgacaa gaatgaattc tgtcactctt ctcacagacg
     3661 gacaagagaa attggattca ctgcttcaag atctaaaaaa agccaaacat tcgatccata
     3721 tcgaatatta cgcatttgtg acagataata tcggccagca agtcttacat gttttagaag
     3781 aaaaagccgc agaaggcgtg gaagttcgaa tattatatga tgcatttggc tctcatggta
     3841 caaaagcaaa agatttcaat cgtctaatca aaaatggtgg acatgtccat acatttgtta
     3901 cctcacaaaa ggcattactt cgtttccgat tgaattacca tgatcaccga aaaatcgttg
     3961 tgatcgatgg aaagattagt tataccggtg gtttcaatat tgccaatcaa tatgtaaata
     4021 caacaaaaaa attcggctat tggcgcgata cgcatatacg gattttcggt gccgcttctt
     4081 ctttgctcca gcttcgcttc ttaacagact ggaacgtctc ggtacctgaa gaaaaaaagg
     4141 tcggctatca tttgaattat ttctttaaaa aagcagatcg agatgaatct aagcttgctg
     4201 atacatccat ccagcttgtt tcaagcggac cgaataacga aagggaacaa atcaagcttt
     4261 catttatcaa attgattact tctgctaaaa aacgtgtttg gatacagaca ccttaccttg
     4321 ttcctgatga aagtgtcatt gctgctttaa aaatcgcaac tgcctctggt gtagatgtga
     4381 aaatcatgat tcccaacaaa ccggatcatc cttttattta tcgagcaaca caatattatg
     4441 ctcggcagct gatcaaggaa aatgtacaaa tccttgtcta tgagaacggc ttcctccatg
     4501 caaaaacatt gataatggat gatgaaatct gcatggtagg ttcagcaaat caagatattc
     4561 gtagctaccg attgaatttt gaaacaagtg ctgtcattta cgatcctgag tttttagaag
     4621 aacttgctac tcagttcaaa gaagatgaga cacattgttc atccatgaca actgaaacag
     4681 tcaaggaaat gtctaactgg ctattattca agcaacaaat ttctcgatta ttttctccaa
     4741 tcctataatt tttttattca agtagagaaa aatatactaa gattaaaggg actgtgacaa
     4801 aaatcttgtc acagtccctt cttccgaaca aacggtgttc tcctgccaac tcctcggtca
     4861 caagtcacaa tattcaacaa acatgagaag ctgttttttg aacttgttcc ttgtgactcg
     4921 gagctggacg gcaggctcac gacctctttc ttttactcta attcaccagc tgcccaatga
     4981 ttgatgggtc catatttgtg ccctacattt atttcttcac gaattgcacg gtttacatag
     5041 tcttttgcca atcggatcgc ttgttcaact gtttttcctt tcgctaactc agctgcaata
     5101 catgcagata gcgaatcgcc agttccgttg atccggtcgg taggataaaa tggtgcattt
     5161 aaccaaaacg attttcctga ttcgagcaat acgtagtcat tgactgtttc ttgctgcgca
     5221 tctttagcat gatgtccttt gatcataacg ttttttgcac ccatatcttg cagttctttt
     5281 gctgcttgca caaaatcttc ttcagctgct aatgtccgtc cagtcagctt ttctgcttca
     5341 taaaaattag gtgtcagtac ttcggccaaa gggacaagct tttctttcaa gctttgcaaa
     5401 gcagattctt ctagtaaaag atttccatgt ttcgttacga ttacgggatc cacgactaat
     5461 ggtccaaaat catatttttg gtaatttttt acaactgtct caatcaactt tgaatctgct
     5521 agcatacctg ttttagctgc acgtatttga aagtccttcg caatcagttc aaattctttg
     5581 tcgataaaat ctgttggcaa tgtcacactt gctccgattc cgtaagaatt acctgcaaca
     5641 catgcggtca tgacagaaac accgtaaaca tttcttgtaa agaatgtatg catatctgct
     5701 tgcatccctg cgcttccatc gctatctgat cctgcgatcg tcattgcttg tacatactga
     5761 tcttccatca aatcgattcc tccattttta taaaaagatt tttcataatg ctgttactgt
     5821 ttctatcata tgtttttcaa agtatccctc agtaaatata ccactacctt ttcttggtaa
     5881 tcaaatttat ttgaaaaaac atttgtaata aatcagaaaa tagttgtcat ttgtttgtat
     5941 tcgctattct aa
//
LOCUS       DAXLPY010000110         5912 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.112, whole genome shotgun sequence.
ACCESSION   DAXLPY010000110 DAXLPY010000000
VERSION     DAXLPY010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5912
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.112"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(99..1229)
                     /locus_tag="ACF3UF_002567"
     CDS             complement(99..1229)
                     /locus_tag="ACF3UF_002567"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFD3672628.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACF3UF_002568"
     CDS             complement(1878..3080)
                     /locus_tag="ACF3UF_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3672629.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACF3UF_002569"
     CDS             complement(3140..3343)
                     /locus_tag="ACF3UF_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFD3672630.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACF3UF_002570"
     CDS             complement(3485..4552)
                     /locus_tag="ACF3UF_002570"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3672631.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACF3UF_002571"
     CDS             complement(4610..4717)
                     /locus_tag="ACF3UF_002571"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672632.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACF3UF_002572"
     CDS             4880..5692
                     /locus_tag="ACF3UF_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672633.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1748 a         1219 c          949 g         1996 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgggctct ataatttatg
     5881 ggactgatga atcagaattg attcttcagc cc
//
LOCUS       DAXLPY010000111         5689 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.114, whole genome shotgun sequence.
ACCESSION   DAXLPY010000111 DAXLPY010000000
VERSION     DAXLPY010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.114"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(488..1297)
                     /locus_tag="ACF3UF_002573"
     CDS             complement(488..1297)
                     /locus_tag="ACF3UF_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3672634.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="ACF3UF_002574"
     CDS             complement(1297..2043)
                     /locus_tag="ACF3UF_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3672635.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="ACF3UF_002575"
     CDS             complement(2061..2528)
                     /locus_tag="ACF3UF_002575"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3672636.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="ACF3UF_002576"
     CDS             complement(2528..2938)
                     /locus_tag="ACF3UF_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3672637.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="ACF3UF_002577"
     CDS             complement(2949..3962)
                     /locus_tag="ACF3UF_002577"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3672638.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="ACF3UF_002578"
     CDS             4179..4913
                     /locus_tag="ACF3UF_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3672639.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="ACF3UF_002579"
     CDS             4897..5607
                     /locus_tag="ACF3UF_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3672640.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          942 g         1720 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgcttt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAXLPY010000112         5615 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.115, whole genome shotgun sequence.
ACCESSION   DAXLPY010000112 DAXLPY010000000
VERSION     DAXLPY010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.115"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            249..1799
                     /locus_tag="ACF3UF_002580"
     CDS             249..1799
                     /locus_tag="ACF3UF_002580"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD3672641.1"
                     /translation="MSDKNTYARRSQRHKQEPDSCENTNQLNEAVKPQTGNENKQPKI
                     PKKKSNYSKYIFALFTALILVIVVTGGYIVYTLKQQEAEAQAKYETAAKNLMASIQEE
                     QDQSGISTKIDTINDGENKCLVYRPVDENTVPFKNANQLLDELAQKQQKKHREKEVLT
                     VARIKATAISSKVNQYRIEADSFIWDRSKENFKKPDSISEKDIYIFKKTGKEITNKDL
                     FPDEGSLLGIQQVIQQSILDQAKEPEKIIDAVLTMDRISYDSKMTYTPDELTIVLPKN
                     STGTSKVTLKYKDIAPFIDTDLVSQESIKDTLPALDENKKYVALTFDDGPNNSSTLDL
                     LNILKTDNVKATFFMLGQMVDQNPDVAKQVHDEGHEVACHSYSHPQLNTLSTDELQSE
                     INKANKAIFKATGVLPRNIRPPYGAIDKKSAETIGMPIIQWDIDSQDWKSKNPRAINN
                     VVKQNVYNGAIILIHDIHPESVKAIPNMISMLKNKGYEFVTIDQLLSGKQKPLHQYFG
                     MNDERLVD"
     gene            2084..2303
                     /locus_tag="ACF3UF_002581"
                     /pseudo
     CDS             2084..2303
                     /locus_tag="ACF3UF_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3315..>5615
                     /locus_tag="ACF3UF_002582"
     CDS             3315..>5615
                     /locus_tag="ACF3UF_002582"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672642.1"
                     /translation="MFYQRSEKKFKYAIKKKKGGGGAASFIIGAMFLGIGLISCPTVS
                     FASETTEINQSTEIQSTLNNSILKESNSEEKQNIDVSEDSAINKDLELASKATISESE
                     NSFGETTNNQENTNLSEDSIEVQPESIIQKEVLTDNDAIQQLEVHPHEDSDDAALVEN
                     QMTRVTEESIKSNTSQVDKDTTVLSNTTRDLVNLEDTAIENVTPQKTIKKDSISLLEE
                     NNSSSASRTLRRSVRSLDVQTGENFLEDWALPDNSNISGSLITQTGITYVGVKTDDPT
                     QLHLKMAYRAAATPASIDWIYLRVDPELTKYIEEINIKNTVNIGAQVGYQRYFEKVDT
                     NTLSNVNTFGTPTGVSDAYAQVDQKTGGIYRVLLDKFFIRIPGTNPKSRGALSGNWGV
                     FPSVPLEAERYEANIYIKLSKDVAELQQELGRDKFGVQLRLQGQSSSGVATIAKESLN
                     KNTIVDLSQEEPDENNSNWLNSPSVHTITTTYEGKQMGSDGQFSSILEGTDKSLIRVQ
                     NTIMNNLLYGTALDLGRPVSFNIEIDPQILNLVSDDDYITIWQVYRENSINHHDGGSN
                     APVMLKKNMFVDNKIKIEVNKDKAGQYGNGVYYVNAVESFMNTLSSSPFVGANFIDIP
                     VMPKSLIEDEDQLISAEIKTWFTDKKNDQERIVRNSLASSYINLFPTTINFYDYSTKD
                     TEQLLKLRESTYLVSTFGQEINGMDMGETYEISNYEFVTADPESLIITQKDGNIINLY
                     YKKLSSDAEFYEPEVEKEEVNYGETID"
BASE COUNT         2097 a          818 c          964 g         1736 t
ORIGIN      
        1 aattaatcta tcgaatggta caatttcaaa aactaaaatc aaaactagtg attctaatgt
       61 tatcaaaact gagttgaaaa ttaagtagcc acaatatcta aagtggtgag gaattagcga
      121 taattactac gccgaaagta aaagaataat agaaaaaact ttccttaaaa attatctatg
      181 aattcgtttt cattataatt gcgctgtttt attttacttt atgatgataa atggagggat
      241 aaagtcatat gtctgacaaa aatacctatg cacgtcgtag ccaacgtcac aaacaagaac
      301 ctgatagctg tgaaaataca aatcaattga atgaagctgt aaagccccaa accggaaacg
      361 aaaacaaaca accaaaaata ccgaagaaaa aatctaatta tagcaagtat atattcgcat
      421 tgtttaccgc acttattcta gtaattgtcg ttactggcgg ctatattgtt tatacattaa
      481 aacagcaaga agcagaagct caagccaaat atgaaactgc tgcaaaaaat ctcatggctt
      541 caatccaaga agagcaagac caaagtggaa tttcaacgaa aatagatact ataaatgacg
      601 gagaaaataa gtgccttgtt taccgtccag ttgatgaaaa tactgttcct ttcaaaaatg
      661 caaaccagct cttagacgag cttgctcaaa agcaacaaaa aaagcatcgt gaaaaagaag
      721 tgctcacagt tgccagaata aaagcaacag caatatcttc taaagttaat caatatagaa
      781 ttgaagcaga tagttttatc tgggatcgca gtaaggaaaa tttcaaaaag ccagatagta
      841 tttctgagaa agatatctat attttcaaaa aaactggcaa agaaatcaca aataaggatt
      901 tgtttccaga tgaaggaagt ctcttaggta ttcaacaggt gattcagcaa tccatacttg
      961 atcaagccaa agaacctgaa aaaatcattg atgctgtatt aacaatggat agaatttctt
     1021 atgatagtaa aatgacttat acacctgatg aattgactat cgtcttacca aaaaattcaa
     1081 ctggaacttc taaagtcact ctaaaataca aagatattgc gccattcatt gatacagatc
     1141 tggtttcgca agaaagtata aaagatacat tacctgcatt agatgaaaat aaaaagtacg
     1201 tcgctcttac ttttgatgat ggtccaaata atagctcaac acttgatttg ttgaatatac
     1261 taaaaacaga taacgtgaaa gctacttttt tcatgttagg acagatggtg gatcaaaatc
     1321 cagatgttgc aaaacaagtc cacgacgagg gtcatgaggt agcatgtcac tcgtattctc
     1381 atccacaatt gaatacactt tcgacagatg aattacaaag tgaaataaat aaagctaata
     1441 aagcaatttt caaggctaca ggcgtcttgc ctcgcaatat ccgtccccct tatggcgcta
     1501 ttgacaaaaa aagtgctgaa acaattggca tgccaattat tcaatgggat attgactcac
     1561 aggattggaa atcaaaaaat cctagagcaa tcaataatgt tgtcaaacag aatgtttata
     1621 atggtgcaat catcttaatc cacgatatcc atcctgaatc agttaaagcc ataccaaata
     1681 tgatctccat gttaaaaaat aaagggtacg aatttgtgac gatcgatcaa ctattgtcag
     1741 gaaaacaaaa accattgcat caatattttg gtatgaatga tgagcgacta gtagactaac
     1801 tgtaattaga ttgagtggta tttgaagaaa ttatatttgt agtttcctta tttgatgaaa
     1861 agtcatgtaa aacaaattaa taaagagtat taagtatact aactgttgta agtatactta
     1921 atactctttt agttattaac tttagttagt ctcgttagcg tagcgtacga aacaaaaaaa
     1981 cacgcatttc tgtgcgtgga cgaaatagct ttagcgataa aaaactcctt tcgatatact
     2041 aataatggct actaaccgca tatcagatcg aaaggagttt ctaatgttta ccgacgataa
     2101 aagtgtagca catacgagat gtcatatttt ctttacccaa agtatcgacg aaaagtgatt
     2161 tatggaaagt taagagtagg tattggtcag atattaagaa aattgtgtga gatgaaaaat
     2221 attgaaatca ttaaagctca tgttatattc atttgttagt aagaataacg tcaaaaatta
     2281 gtatttccag ttttatgggt tactaaaaag acgtcactga tcaatttaga aaggtaaata
     2341 tattctggta ataaagatag actgaacccc gtaaaaacct cattgcaacg aatcaaggaa
     2401 agacgctttt gcttctccct tgattgggca cattctttga ttttgatttt tgatattgat
     2461 tatatctttt aattcgccat agttatttat acaataaaga actaaatttt ctaagaatag
     2521 actttctaga ttctttattt tcagctttta ctaaaatgaa gtcatcctat ccattttatt
     2581 caaaacaaat tttttaataa gaaagatctg ttctttttct ttgaaggaaa agaaaaagaa
     2641 aacgtgaaaa gaaacttatg caatctatac tgctaataac ctctataaga tcgttgtata
     2701 ttgatattat tatcatgttt attttaggaa gaatactatg agttaagttt ttaataagaa
     2761 atgtcgagtt tatgaacctt ttttcaaagt tgaaaaaatt tctttatttg ataatggcga
     2821 tcaacatctt ttagaatgga tgcaatggtt aaactgattg ttgagtatat aatcacttgt
     2881 ttgtttttat ttatcttttc cccactatat ggttaatagt cagccacttt agaaagagtt
     2941 ttagctgttt tttacttgag gaacatcatt ttattggcag tcttatttga cttattaagt
     3001 gaatttatat taaaaaaatt cgtttttact cataataatc tctactaaga ttcctccttt
     3061 atttgagtat cattctcatt tgattataaa ttaaatcctt ccctttatta ttatcaacga
     3121 gaaaaaaggt taaatgaata caaaagaaat agatcttttg tgactaataa aaagtgaacg
     3181 ttcatattga aaatattata aatttaattt aacatataaa ttgagaaagg gaatctattc
     3241 taacctttct tataaaatga acgttcgttt ttaggatttc tttttgataa ctttttatgt
     3301 taggaggata aagtatgttt tatcaaagaa gcgagaagaa gtttaagtac gcaattaaaa
     3361 agaaaaaagg aggaggtgga gcggcttctt tcattatcgg tgcaatgttt ttaggaatag
     3421 gattaatttc ttgtcctaca gtttcttttg ctagtgaaac aacagagata aatcaatcaa
     3481 ctgaaatcca atctactttg aataattcta ttctaaaaga aagtaattca gaagaaaaac
     3541 aaaatattga tgtgtcggaa gatagtgcta taaataaaga tctagaacta gcttcgaaag
     3601 caaccatttc tgaatcagaa aattcatttg gtgaaactac taacaatcaa gaaaatacaa
     3661 atttatctga agatagtatt gaagttcagc cagagagtat tattcaaaag gaagtcttga
     3721 ctgataatga tgctattcaa caattagaag tacatcctca tgaagatagc gatgatgctg
     3781 ctttagttga gaatcagatg acaagagtta cagaagaaag tataaaaagc aatacttcac
     3841 aagtagataa agatacgaca gttttatcta atacaacaag ggacttagtt aatttagaag
     3901 atactgctat agaaaatgtt actccacaaa aaacgatcaa aaaagatagt atttctttat
     3961 tagaggaaaa taattcatca tcagcatcaa gaactttacg tagaagtgtt aggagtcttg
     4021 atgttcaaac tggagaaaac tttttagaag attgggcact accagacaat tctaacattt
     4081 ctggaagttt gattactcag actggaatta cttatgtggg tgtaaaaact gatgatccca
     4141 ctcaattaca tttgaaaatg gcttacagag ctgcagcaac gcctgcttca attgattgga
     4201 tttatcttcg tgtggatcca gagcttacga aatatattga agaaattaac ataaaaaata
     4261 ccgtaaacat cggtgcacaa gttgggtacc aacgatattt tgaaaaagta gatactaata
     4321 cattgagcaa tgtaaatact tttggaactc cgacaggtgt aagtgatgct tatgcacaag
     4381 tagatcaaaa aactggcgga atctatcgtg tgttattaga taaatttttc atacgtattc
     4441 cgggcacgaa tcctaagagt cgaggcgcgc tatctggaaa ctggggggta tttccatctg
     4501 ttcctctcga ggctgaaaga tatgaagcga atatctatat aaaattatcg aaagatgtcg
     4561 cagagttaca gcaagagctt ggaagggata agtttggtgt tcaacttcgt ttacaaggtc
     4621 aatcaagttc tggtgttgca actattgcta aagaaagttt aaataagaat actattgttg
     4681 atctttcaca agaggagcca gatgaaaata attcaaattg gttaaactca ccatctgtcc
     4741 atacaattac taccacttat gaaggaaagc aaatgggaag cgatggtcag ttcagtagta
     4801 ttctcgaagg aactgataaa agtctgatta gagttcagaa tacgatcatg aataaccttt
     4861 tatatggaac ggcacttgat ttaggtcgac ctgtttcatt taatattgag attgatccac
     4921 aaatattaaa tttagtttca gatgatgatt atattacgat ttggcaagta tacagagaaa
     4981 atagtatcaa ccatcatgac ggtggatcaa atgcacctgt catgttgaaa aagaatatgt
     5041 ttgtagataa taaaataaaa attgaagtca acaaggataa agctggtcag tatggaaatg
     5101 gagtttacta cgttaatgct gttgagagct ttatgaatac tttgagttct tcaccatttg
     5161 ttggtgcaaa ctttattgat attcctgtta tgcctaaatc tctaattgaa gatgaagatc
     5221 aattgatatc agcagaaatt aaaacatggt ttacagataa aaaaaatgat caagagagaa
     5281 tagtaagaaa ctcacttgct tcaagttaca ttaatttatt ccctactacc attaatttct
     5341 atgattattc aaccaaggat acagaacaat tattgaagtt acgtgaatca acctacttag
     5401 tttctacgtt tggtcaagaa attaatggaa tggatatggg ggaaacatac gaaattagta
     5461 attatgagtt tgtgactgcc gatcctgaaa gtttaataat cacacaaaaa gatggaaata
     5521 tcattaattt gtattataag aaactttcta gtgatgctga attttatgaa ccagaagtag
     5581 aaaaagaaga agtcaactat ggagaaacga ttgat
//
LOCUS       DAXLPY010000113         5566 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.116, whole genome shotgun sequence.
ACCESSION   DAXLPY010000113 DAXLPY010000000
VERSION     DAXLPY010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.116"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(6..692)
                     /locus_tag="ACF3UF_002583"
     CDS             complement(6..692)
                     /locus_tag="ACF3UF_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672643.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(670..1164)
                     /locus_tag="ACF3UF_002584"
     CDS             complement(670..1164)
                     /locus_tag="ACF3UF_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFD3672644.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(1184..2404)
                     /locus_tag="ACF3UF_002585"
     CDS             complement(1184..2404)
                     /locus_tag="ACF3UF_002585"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3672645.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            2551..4386
                     /gene="lepA"
                     /locus_tag="ACF3UF_002586"
     CDS             2551..4386
                     /gene="lepA"
                     /locus_tag="ACF3UF_002586"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFD3672646.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(4480..>5566)
                     /locus_tag="ACF3UF_002587"
     CDS             complement(4480..>5566)
                     /locus_tag="ACF3UF_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3672647.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT         1699 a         1115 c         1063 g         1689 t
ORIGIN      
        1 ttttattagg tatttttcac tttttctaat ttataacttt caaagtaacg ctcatctttt
       61 ttactttgag accatgcaaa caatcccatt aaggcagcac ctatcgtatt tgtcagcaag
      121 tcgcccatcg tatccatcaa tgctgctcgt ccgacaaaca gtgtgccatc agaagcagca
      181 aaacgttgaa gattcatgcc taagaactgg tcgcataaga attcccagaa ctcccaaaac
      241 acgccgcaaa gtccagcaaa cgcaaagccg aataagagga acaaccaagg actggttttt
      301 gatatctcag catctttcat caagtaacca atcaatccat agccaagagc tgtcaggacc
      361 attggactca ccgcatgtaa gattttgtcc caaaaagaga tgatactgat caaatgcatc
      421 cctgtgccta aaaagacaga gatgaacaag aaaaaccagt aaaacaaaac gattgctgct
      481 ggtattttaa gtttgaaaac tttcaaaatg acttgtggca tgaaaatcaa tgcaatccct
      541 aataaagatt ccacgataaa tgtgattcct tgagaagtcg aatatttttg tgtgataaat
      601 tcataaaaat tatagcagac aacgaataca ccaaaagcaa gtaaagctat ttgcaccttt
      661 ttgatttctt taatcactga aagtccctcc atctaaaaat ctttttactt ctgaaagcaa
      721 ctcaatttct gaagaaacca cttttccgtt caatttgatc aaacctattg tatataagtt
      781 caggtagtga aattgatttt cagctgtttc ttgtagtgca gcgatttttt tcgggtgggt
      841 tccgccttgc tgtcgagtat cagtatataa gccgatcact gggatgcctt tcgcataagc
      901 cacaccgatt tccgatgcta ccccggcatc gatcgtcagc ccatctagta aagcaatcat
      961 taaatcacta gccaacactt tttctgtgtc agcaagagca atcattcgac tgtctgcata
     1021 agcagttttg tcattgattg cttcattttc ttgaggaaga tagatcgaaa gctcagaaga
     1081 gagctctctg atttctttaa ctaactgttg gttatataac aaatcacttt tagcaaacat
     1141 tggtgcggca aaataaattt tcatctaaac atcatccttt ttatcaaaaa taatcgctaa
     1201 agtaagcttc catgtttgga atgatacgct ctagtgactt cagtgtttct tcatctgttt
     1261 ctaaccgttc gattcttgcc aaataagaag cacggcgata attcatcatc aagcaagtca
     1321 atgtttggat atccagtcga acggattttc ctataggttc atttaagaca cggacttgtc
     1381 cctgttcatc ccatgttaaa gcgaagacac cattattcca aggagcgaca ggatcttcaa
     1441 tgatgaaatg aaaagcatca gctgttccaa caaacggaaa ccgttgaagg aattctttta
     1501 catcaacgat ccgagccata aaatatggtt cgatctgctc tttgatctga ctatcttcaa
     1561 tcaaaaatgc taaaggctca tttttataaa tatctccatg tacccagtag atcatggaaa
     1621 aatgtgcgga aataaagttc cataagccat ttcgagcttc ttgatcaaga tagaacattt
     1681 cttttacgtg aaatatttct tcagctaccc agtagaacag aacacctctt ggttcatggt
     1741 tgctatcgta gtagacagcg gctgtgcgct catcttcatt ttcgaaacgc caatactctt
     1801 cccaatgaaa atcactgcgg aataaagcac catggttttg ttgggcaaat ttgtcataaa
     1861 cggaaaatac gtctggatga tcaactggta atcgctcaac cataccactt actgggattt
     1921 gtttaggtag ctgtgtatct ctgattttaa aggaaagttt atcagacatg atttcccatc
     1981 ctttacgccg atagtagggg atactgtaag gatacaaata agagatccat tgcttattct
     2041 tgcgcatatt atccaatgca acgataatta gatcttgcat caatccatgg ttagcatatt
     2101 ctggataagt tccaactcca gtcacaccac ccattttata acgtgcaccg tgaatattga
     2161 cttcacaagg atagatagcg atttgagaga tcagtttatt ttcgtggaac catccgaaca
     2221 ctttcgatac ttccaaaatc ggttttttgg aacggataaa agctcgttta ttctcaaacc
     2281 cgctttcctc gatgtctgct tcagtcactt ggaacacata ggaaagcaat tcattgaatt
     2341 gatcgatatg ttcttgagtg accggtttta attcaagatt ttctctaaaa tctttttgat
     2401 ccattttttc atctccattt attagcttga taacagtata gcaaaattct acaaaaaaaa
     2461 cttctatagc tgactaatta aaaactcttt aaattactgc ttttcgttgg tataatggaa
     2521 agtgctgatt atatgaaaag aggagacgct atggatataa agaaaatgaa agaacgccaa
     2581 gagcagattc gtaatttttc gatcatcgct catatcgacc atgggaaatc tacattggcc
     2641 gatcgtattt tagaaatgac gcacactgtg acgtctcgcg aaatgcaaga tcagctgtta
     2701 gactcgatgg atttggaacg tgaacgtgga atcacgatta aattaaatgc tgtagaactc
     2761 aattacacag cgaaaaatgg agaaacatat atctttcact tgattgacac cccagggcac
     2821 gtcgacttca cctatgaagt ctctcgaagc cttgctgcct gtgagggtgc cgttttagtg
     2881 gtcgatgcag cacaaggaat cgaagcacaa acattggcca atgtttattt agcgttagac
     2941 aatgatttgg agatcctgcc agtcatcaat aaaatcgacc tacccgcagc agatcccgaa
     3001 cgtgtccgtc aagaaatcga agacgtaatc ggaatcgatg ctagtgaagc tgtattagcc
     3061 agtgccaaat cagggattgg gattgaagat attctcgagc agatcgtgga atatgttcct
     3121 gcaccaagtg gagacttaga tgcaccgcta aaagctttga tctttgactc tatttatgat
     3181 agttaccgcg gtgttgttct aaatgtccgg atcacggacg gtatggtcaa acccggagac
     3241 aaaatcaaac tgatgagtaa tggcaaaaca tttgatgtta cagaggtcgg ggtcttctcg
     3301 ccaaaagcag ttgctagaga ctttttgatg gtcggtgatg tcggttatat cacagcaagt
     3361 atcaaaactg tccaagatac acgagtaggg gatacagtaa cgttagcaga caatcctgcc
     3421 gctgaagctt taccaggtta ccgaaaaatg aatccgatgg tttattgtgg tctttatcca
     3481 attgatactt ctcgttacaa cgatttgcgg gaagctttag aaaaactgca attgaatgat
     3541 gctgctttac aattcgaacc agaaacctct caagcattag gttttgggtt ccgctgtgga
     3601 ttcctcggac ttcttcatat ggatgtcgtc caagaacgct tggaacggga attcaatcta
     3661 gaattgatca cgactgcacc atccgttatt taccatgtta ataaaacgga tggtacgact
     3721 gctacagtag ataacccggc agattttcct gaacctgtaa cgattcagga tgtagaagaa
     3781 ccattcgtca aagcacagat catggtccca aatgattttg tcggtgcagt aatggaactt
     3841 tctcaacgaa aacggggaga attcattacg atggattatt tagatgatta ccgagtaaat
     3901 gtcgtctata atattccgct ttctgaaatt gtctttgact ttttcgacaa attgaaatca
     3961 agcacgaaag gctatgcctc attggattat gaaatgtctg gttatcaaaa aagcaagtta
     4021 gtgaagatgg acatcttgct gaatggagaa aaagtcgatg cattaagctt tatcgttcac
     4081 cgagactttg cctatgaacg tggaaaagca atcgttgaaa aactgaaaaa actaatccca
     4141 cgccaacaat ttgaggtgcc aatccaagca gctattggac aaaaaatcgt tgcccgttca
     4201 gacatcaaag ccttgcgtaa aaacgtcttg gctaaatgtt atggtggaga tgtttctcgt
     4261 aaacgtaaac tcttagagaa acaaaaagaa gggaagaagc ggatgaaaca aatcggctcc
     4321 gtcgaagttc cgcaagaagc cttcatggcc gttctgaaaa tggacgagga cgaaccgaag
     4381 aaatagcaag ggtttgtttg aaaacagtgt aaaaaataaa ccatgtttac atggatttgc
     4441 caccggtttg ccaccggtgg tttttttcgg tggcaaaaat caagaattct ttctaagatt
     4501 ttccatgata tcgaccgttt catttctcat cttatctgtt acatgcgagt aagtatccat
     4561 cgtaattgaa attctgctgt ggcccaatcg ttcagagatt tctttcattt ttgcgccatt
     4621 ttcgagaaga agtgtagcat gagtatgtct gagagaatgg aagttaaaag agagggagag
     4681 tgcattcgat atcctcctag tattccattt cactacactt ggcgtaacta gctcaccgtc
     4741 ttccttcgta catactgcat ttgaatcaat gtagagcttt ccatacttca ttcgattttc
     4801 taattgttgt ttcttatgtt ttttcagaat tgctagcaag gtttgtccaa taaaaatcgt
     4861 tcgattggaa ctgcttgtct ttggcgtacc atatacccat gcgccgtcat tctttaccat
     4921 ttgtttctct acagtaattg ttccatttga aaaatcgaca tcatcccacg tcagaccaca
     4981 aacttcgcca acgcgcattc ccgtataaaa tccaatattc aaaggaatat agaaaggatg
     5041 tccttcagga gtaatttcta gcatatgatc aaagtcctca agagaaatga tttttagatc
     5101 ttttttagtc gttggtcgtg cttcatattt tggtattttt acatacagca taggattttg
     5161 cttgattaat ccccaaggat aaaccgccat attcagcgca ttcttaagga cagagtgagt
     5221 aatagtcatt gttttcttcg agtaaccctt tttaaattca gcattgatga aattttgtaa
     5281 aagagcaggg gagagatccg taagtttttt ctttcctaaa taaccgttta tatgattttt
     5341 gatggtaaat cggtagtttt cataggtatt gtattttaga tttagtttaa cgtattcctc
     5401 catccaaaaa tcaaggtatt gttttactcg agtatccgta cctaaaaagt attgtcctgt
     5461 ttcgtcaata tctgataaaa cttttcgtaa agcagcttcg gcctctggtc gggtgtctcc
     5521 gccaactttc tccacttttt ttcttgagcc atcatcattg atatct
//
LOCUS       DAXLPY010000114         5340 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.117, whole genome shotgun sequence.
ACCESSION   DAXLPY010000114 DAXLPY010000000
VERSION     DAXLPY010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.117"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(62..286)
                     /locus_tag="ACF3UF_002588"
                     /pseudo
     CDS             complement(62..286)
                     /locus_tag="ACF3UF_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="ACF3UF_002589"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ACF3UF_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="ACF3UF_002590"
     CDS             2092..3132
                     /locus_tag="ACF3UF_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFD3672648.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3956..4288
                     /gene="traE"
                     /locus_tag="ACF3UF_002591"
     CDS             3956..4288
                     /gene="traE"
                     /locus_tag="ACF3UF_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFD3672649.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="ACF3UF_002592"
     CDS             4907..5248
                     /locus_tag="ACF3UF_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFD3672650.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1769 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttt tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattaa
     4861 tataaagcat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgacgat taataaaaag gtagtattac cttaggcatt gagtaaggaa
//
LOCUS       DAXLPY010000115         5285 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.118, whole genome shotgun sequence.
ACCESSION   DAXLPY010000115 DAXLPY010000000
VERSION     DAXLPY010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.118"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            84..1130
                     /locus_tag="ACF3UF_002593"
     CDS             84..1130
                     /locus_tag="ACF3UF_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3672651.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKM
                     YKTAYNMLWRIYNR"
     gene            1144..2223
                     /locus_tag="ACF3UF_002594"
     CDS             1144..2223
                     /locus_tag="ACF3UF_002594"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3672652.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            2242..3666
                     /gene="wzy"
                     /locus_tag="ACF3UF_002595"
     CDS             2242..3666
                     /gene="wzy"
                     /locus_tag="ACF3UF_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HFD3672653.1"
                     /translation="MKEKINILMFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAIC
                     TWHWRKGDSIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSES
                     DMIMVKWYSCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIV
                     VPIVFVSKLLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKV
                     ITRFVFIIFALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIG
                     IYILNVITKARDGGGLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNG
                     IYPFANTYLTSLLGSISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNG
                     GYIGGIVYIFIIGIVIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIV
                     KNFVYGVLIILLINFFLQQFNKRL"
     gene            3712..5217
                     /locus_tag="ACF3UF_002596"
     CDS             3712..5217
                     /locus_tag="ACF3UF_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFD3672654.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWARKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIILVNVLFYRRYVVKIISKIIVKIKKI"
BASE COUNT         1892 a          616 c          945 g         1832 t
ORIGIN      
        1 ggaattagtg ctaagtttgc attgaaaaac aaatgggtat ttttaattta tatttataac
       61 aaattgataa agaggtaata ataatgtcag ttaagattag tgtaattgta ccttgttata
      121 atgttgaaaa atatattgat gagtgtataa atagtttgat aaatcaaaca ttgaaagata
      181 ttgagattat tttgttaaac gatggttcaa cagataatac gttggcgata ttaaagaaat
      241 atgaaaagct tgattctaga ataaaagttt acgaacataa aaatatgggg ttagggccaa
      301 ctagaaatcg agggattaaa atagctaatg gagaattttt ggcttttgtg gattctgatg
      361 attttgtttc caatactatg tttgaaagtt tatataattg tgcaattgca gagaatgcgg
      421 acattgcaat tggagaagta ggcatttttt ctgatagaga aatagaaaga gtaaaaataa
      481 gaaaaagtct aacgaactta aaaacaattg aattagcaac atataataag aaagaatttt
      541 ttaagcaatt ctatttcaat cgtttatatt cacataatgc ttgggataag atatatagac
      601 gtagtttagt attagagttt aatttatcat ttggtgataa caaaataatt tttgcagaag
      661 ataattggtt tcaattacaa gtatttatga caaatacaag aatctgtttc gtagataaat
      721 tgtgttatta ttatcgccaa caaaataatt ctataatgca taagccaaaa agtaatttgg
      781 tttttagaca tggaaatatg attgctgatt atgaaaagtt gataaggcaa aatggaaaca
      841 acataataga taaaaaagct tgtatgttgg ttgcatttga tgtactaatt atggagattt
      901 ttaatcaaaa aaacgttggt ggaacatgtg aagattataa gaatgcatta gtttctttga
      961 aacatcataa aatattgaga gaaaatattt caaatatagt tagaatgaaa gcatatgaac
     1021 ttgaacctaa tatgagaaag aagttagccc ttgtgaccat tagtataatg tttaatttta
     1081 aaatgtataa aacagcgtat aatatgctct ggagaatata taatcgataa agaggtagga
     1141 aatatgagga aattgacctt tgtgatagga attatgggaa aaggaggggc agaacgagta
     1201 attgcgaatt tggcaaataa ttttattcaa gataactggg aaattgatat tataactata
     1261 tatgggaatc ggcaagacta tgaactgaat agaaaaatac aggtacatcc aataatatgt
     1321 aaaagttcgt ttcgtgcatt tagacctttg gaacgcttta aggaacttag gaaaaaaata
     1381 agggaaatac agcctgatct ggttatttcg ttccttgctg atgtaaatat ccatgtcatt
     1441 atttcattgt taggagtaaa acaaaaatta attgtttctg aacgaaatga tccacaacgg
     1501 aatccagaag aaccatggat taggaaaatt agagattttc tttataaaaa tgtagatgga
     1561 attgtttttc aaacaccaga cgcaaaaaaa tattttagta agatcaatga taaaaaagta
     1621 aaaacaatta taattcccaa cccaataaag gaaaatttac cttattataa taaaactaca
     1681 agtagtaaaa aatttattac tgcatgtaga ttggataaac aaaaaaattt gcccttaatg
     1741 attgatgcaa taggaaaact tattcatgaa ggatatgagt gtgaactgga tatttatgga
     1801 gaagggggat taaaaaccga gcttgaaagt tatatcaacc ataatggatt aacagaattt
     1861 gttcatctaa aagaatttac aaataaaata catgaaaaga tgcaaaatgc ggcaggattt
     1921 gtaatttctt ctgattatga aggtatatct aattctatgt tagaagcact ggctattgga
     1981 gtgccagtta tcgctacaga ttgtccagta ggtggcgcaa gaatgtattt aggtgataga
     2041 aatgaaatag gtcatcttgt tgaatgtaat aatctagata agttaacaga tgcaatgcgt
     2101 agggtacttt tggatagaga aagtgtggta agaaaagcgc aaaaaggaat taaactaaga
     2161 aaagaactga catctaaaaa tatttcaaat atatggtacg aatatttaaa ccagttcttt
     2221 taaccaaaag gaggatattg tgtgaaagaa aaaataaata tattgatgtt ttcgttaacg
     2281 ttagtcgcgt ttacaatatt ttgcgctttt tcattaaatc agaactattg gctaaattgg
     2341 cttggaatat tgatttactt atatgcaatc tgtacatggc attggagaaa aggagattca
     2401 atattttcat tatacacgat ttttttcact ctttttttat tatttagtta tgggcaatgc
     2461 attatgtggg cattcggtat tggaacagat cgtggaatcg gtacaacagt agtagcttat
     2521 ggtacgggga ttattcctag tgaatcagat atgataatgg taaaatggta ttcttgtatt
     2581 tctatgtttg tatttcacat aggagcactc ttatttacga gaaaaaccac actaagaaaa
     2641 gttagttggt atgaatctgg agatgctgat gccgatagaa agtttttatt taaaataggg
     2701 tgtatcattt ctataatagt agtaccgata gtttttgttt ctaaattact agaggtacgt
     2761 atagcattag tccatggtta taatgcatta tattatggtg attatgctac acaaagtgga
     2821 tatttacaaa ttattctata tctttttttt ccagccttaa tatgtttatt aattggtagc
     2881 aacttttcaa aagtaataac gagatttgtt tttattattt ttgctttata ttctttatta
     2941 ggaattatgt caggagacag aggaagttgg ttgtatagct ctattatact catatgggca
     3001 tacactcaat ataaaggaac ctttaattat aaaaaattaa taaagtggct tattttagct
     3061 gttataggaa tatatattct aaacgtaata acgaaagcac gtgatggtgg aggactaagt
     3121 aaacttactt taaaagattt tacatctgta tttgattcag atgattctcc tttagttgat
     3181 tctttttttg aaatgggggg gactatgagt attataactt ttttcctaat aagtggtaat
     3241 ggaatatatc cctttgctaa tacttatttg acctcactct taggctctat atcaacaaga
     3301 atgctatcaa tgtttggaat aaagtttgtt ttattagctg attggttttc tcaggattat
     3361 ttaggaatca cttgggggac tggattctca atgattgcag aagcctatgt caatggtgga
     3421 tacattgggg gtatagtcta tatttttatt attggtatag tcatcggtaa aatcctttct
     3481 aatagtatag acaaccaaga tattgaaaat catcctatga agatgttttt ggctataact
     3541 acagcaaata ttataatggg ttttcctaga gctgcttcat atttaattgt gaaaaatttt
     3601 gtgtatggtg ttttaattat attgttgata aactttttcc tacagcaatt taataaacgt
     3661 ctttaatatt taagcttaat aaaaagataa aacaagtcag gagttgcaaa aatggaaaga
     3721 actgctcggc tcaaaaaaaa cactatttgg gctctggtgt ttcaaataac ttctattgtc
     3781 tgtggtatga tcttgctacg tttgatatta acaaagtacg gatccgaggt taatggaatg
     3841 attagctcta ttaaccaatt tctacaaatt atttcttttt tacaattagg agtaggcgct
     3901 gtaatgcaat caactctata caaaccacta gcagaaaagg ataatttaat gataagtcaa
     3961 atcttagctt ctggagggaa gttttatcgg caaattgcat atattctact agtatacgtg
     4021 ggtttgttac ttgcagtcta ttatgttctc gttcctaatg aatttgggag atcatataca
     4081 atggcaatga ttgcaacatt aagtattaat tcatttgctc aatattattt tggtattgtt
     4141 aatactttgt tattaagtgc tgaccagaaa atttatatta cgtatattgc acagacaata
     4201 gcatttattt ctaatacagt tgcatgtgct ttattaatta gtctgaacac agagatcctt
     4261 atggtaaaac ttattactgc tataatttat cttgcttgtc caatatatta tagatggtat
     4321 gtggatcgaa actataatat aaagaggaat gtgtcatatg ataaggaacc gatccctcaa
     4381 aaatggaatg gggttgcaca acacgtagct tctgttgtac tagatagtac tgatgttgta
     4441 gtgttatcta tattttctaa cctgatatat gtatctatat ataatgtgta caatttagta
     4501 atatacggag taaaacagct attcatggct atgacaaatg gcgttcaggc cttactaggg
     4561 gaactttggg ccagaaaaga aatagaagtt ctttacaaaa catttgcatg gttcgaatgg
     4621 attgtacata ctttgacagt ttttattttt ggctgtaccg gtatactaat cgttccattt
     4681 attcaagtat atacaagagg agtaacagat gctaattata atcaattatc attcgcagct
     4741 ttacttgtaa ctgctaacgc acttcactgt ctgcgtacac cttatcatgt aatgataaaa
     4801 gcagctggta aatataaaga aactcaaaat agttttataa ttgcttcttt gttaaattta
     4861 ggtttatcat taattttggt taaaccacta gggctagttg gagtagcatt aggatctcta
     4921 atttcaatca catatcatac actttggagt gcaaattata attcaaaata tttgcttaaa
     4981 tggccgatga aaaaattcta taaacagtta tttgtaaaca tcttaactgt agttctttct
     5041 tttggggcga catcacaatt gaaaatgatg tcaatcacat atttggattg gattgttctc
     5101 gcaattaaat gtgcagttat tgtatttata tgtataatcc tagttaatgt tttattttat
     5161 agaagatatg tagtaaaaat aattagtaaa atcatcgtaa aaataaagaa aatttaatac
     5221 acaataaatg ttttaataaa cttaataaaa ttatatttgc caaaattaga cacatatatt
     5281 aaatt
//
LOCUS       DAXLPY010000116         4859 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.119, whole genome shotgun sequence.
ACCESSION   DAXLPY010000116 DAXLPY010000000
VERSION     DAXLPY010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.119"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            236..1876
                     /locus_tag="ACF3UF_002597"
     CDS             236..1876
                     /locus_tag="ACF3UF_002597"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFD3672655.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2030..3352
                     /locus_tag="ACF3UF_002598"
     CDS             2030..3352
                     /locus_tag="ACF3UF_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFD3672656.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3414..3845)
                     /locus_tag="ACF3UF_002599"
     CDS             complement(3414..3845)
                     /locus_tag="ACF3UF_002599"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3672657.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3909..4745)
                     /locus_tag="ACF3UF_002600"
     CDS             complement(3909..4745)
                     /locus_tag="ACF3UF_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFD3672658.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
BASE COUNT         1499 a          963 c          902 g         1495 t
ORIGIN      
        1 tctatttatc tatctaacat atcctttatt cttctacttt tctttcttta gcatataaga
       61 gatacgcata gtaatcaagc aaggattgtt gatataaaaa gaacaaatac cgctattttg
      121 atttcttttg actctattac tcatataaat aaaatttatt atacctgctc tttttgacta
      181 tatcctcatc tgactcctat acttcgtttg tattaaaact taggaggaat cattcatgct
      241 tacagggcta aacttattaa ataatccttt tctaaataaa ggaacagctt ttacaaaaga
      301 agaacgggca aaatacggaa tcactggtat gcttccaagt actgtccaaa cattggaaca
      361 acaatctgtc caagcttacg gtcaatactt aagcaaacag accgatttgg aaaaacgtat
      421 cttcttaatg aatctattca atacgaaccg gacattgttt tataaattga tgggcgaaca
      481 tttagttgaa ttcatgcctg tcgtttatga tcctgtcgtt gcggattcaa tcgaacaata
      541 caacgaaatt ttcttgaaac cacaagatgc tgtatttctt tcaatcgacg aaccagaaaa
      601 tatcaaagca agtttgaaaa acgcagcaga tggacgcgac attcgtttga tcgttgtgac
      661 agatgcagaa ggaatcttag gtatgggtga ctggggtgtg aacggtgttg acatcgctat
      721 cggtaaattg atggtctaca ctgccgcggc tggtatcaat cctgcacaag tcttgcctgt
      781 atcaatcgac gctggtacta ataacgaaga attattgaat aatccattat acttagggaa
      841 tcgtcatgct cgtgtagaag gcgaaactta ctacgaattc attgatcaat tcgttcaatc
      901 agctactgaa ttattcccag aattgttatt acattgggaa gattttggac gaggaaatgc
      961 tgcaacgatc ttagaaaaat acgaagataa aatcactact ttcaatgatg atatccaagg
     1021 cacaggaatc gttgtactag ctggtgtatt aggtggattg aatatatcag gtgagcaatt
     1081 gaaagatcaa acgatcttga catttggtgc tggtactgct ggtgtaggta tcgcaaacat
     1141 ccttttagat gaaatgatcc gtcaaggtgt acctgaagaa gaagcacgcc aacatttcta
     1201 tcaagtagat aaacagggtt tattgtttga agatacaaaa ggattgactc ctggtcaaat
     1261 cccattcgct cgtaaacgct cagaattcac taatgctgat gaattgacaa acttagaagc
     1321 agttgtaaaa gcaatccatc caacgatcat gatcggtact tctacccaac ctggagcatt
     1381 cactgaagaa atcgtgaaag aaatggcggc tcatacccca cgtccaatca tcatgccttt
     1441 gtctaatcca acaaaattgg cagaagcaaa agcaaaagat ttgattgaat ggacggacgg
     1501 aaaagcttta gttggaacag gtatccctgc tgctgatgtg gaatataacg gtgtaactta
     1561 ccaaatcggt caagcaaata atgcgttgat gtacccaggt ttagggcttg gtttgattgc
     1621 ttcaacagct acacgagtaa atgctgaaat catttctcaa gctagtcgag cattaggcgg
     1681 aatcgttgat gtaacaaaac caggagcagc tatcttgcct ccagtagcaa aaatcactga
     1741 attctctcaa acgattgctg aaactgtcgc aaaatcagtt gttgcacaaa aattgaatcg
     1801 tgaagaaatc acggatatca aagaagctgt tgaatctgct aaatgggttc ctgaatataa
     1861 atctttagaa gattaagatt gttatagtaa aagaacatac agaaactttg tatgacgtct
     1921 aaaaagaaaa aagcgactgc ggcaaaacag cagccagcca actactgctc ttttgccgct
     1981 tctctttggc ttttttcata cgatacagaa taagaaagga tctgtaaaaa tggcacaaaa
     2041 aacaacaacc gcaactgcag ttgaggaaaa gaaaaaagaa gggttttggt caacaaaaat
     2101 taccggcgta agtttgcccc tttatttgat catggtcctt gtcctgatca ttgcaatggc
     2161 tttaggaaaa ttaccgacga atatgattgg cccaatcgct gttttggtca ttttcggtaa
     2221 tttatttcat tttatcggaa caaaaatccc tatagtcaaa agttatttag gtggtggctc
     2281 cgtttttgcg atctttgcct ctgccgcgat tgctacattt gggatcttac ctgagtatgt
     2341 agtaaaatcc acagaaaact ttgtcagcaa tatgggcttt ttagactttt atattgctgc
     2401 cttgattact ggtagcatcc ttggtatgaa ccgtaatcta ttgatgaaag cttctgttcg
     2461 ttttattccc gttgcactta tttcaatggt cgtctccttt tttgccgtag gactcgtagg
     2521 tatgcttatc ggaaatggtt ttgcaaattc cgttttatat atctcattgc ccgcaatggc
     2581 tggtggtgtt ggagccggag ctgtaccttt atcaacgatt tatgcaaatg ttttaggtac
     2641 ggacgcttct tctatcattt cccgcctgat tcctgcgaca gcaatgacaa atgtcctagc
     2701 tatcattggt gcagcgttag ttgctcgtgc gggacaatca atgccaaaat tcaacggtaa
     2761 tggtaaatta atggaaaaag gcgaccttgg cgatggaaaa cctagaaatg taaaaccttc
     2821 cattccacaa ttaggtgtcg gtttgatggt atcattgact ttcttcatct taggacaaat
     2881 ctgtaactat tttgttccta aagtccatgc ttacgcattc atgatcatta tcgttgttat
     2941 ctgtaaaatc gcaaacctat taccagaata ttacgaagat gcagctatca tgttcaacaa
     3001 cttgattgtc aaaaacttga cagcagctgt tcttgccggt atcggtattg cgttattgaa
     3061 tctaaatgta ttggcttctg ctttgacatg gcaatttgtt gtcttatgtt tgacaagtgt
     3121 tatcgcgatt tcagtagttt caggatttgt cggtcgtttg tttggtttat atccaatcga
     3181 atcaactatt actgctggct tatgcaacaa ctcgatgggt ggtacaggaa atgtagctgt
     3241 cttatctgca gctaatcgga tggaacttat tgcttttgct caaatgggca atcggcttgg
     3301 tggtgccatc gttttgatca tctcaggttt cttgatgcaa ttactttctt agtcaaaaaa
     3361 aatacctgat catcaagtat cggcttgatg accaggtatt ttttgataaa aatttacagg
     3421 attttcaaaa atcttttttg cattttatcg gaatgataac cgatgcgttc ataaaatcgg
     3481 tgtgcttcta ctctgtattc tgcagaatta agtcttattg ctgatattcc tcgtcttttc
     3541 gcttcttcta cgccagtcat caaggccttt ccgattcctc ttttttcagc atgtttagac
     3601 acagcaagtg ccataatatt gaacatcgga tcgctgaaaa tcgattcata ggactccgct
     3661 tgtacatagc cagctgcttt tttagaagta ggatcttcat agaccaagaa aaaatttttt
     3721 tctggctcct tcaacagttt cttcatttgt ctcaccgtaa cggttaatgg tacatcatat
     3781 cctaattgtt ccgcattgat ttctcgtagt gcttctgcat ctcctaaacg catttcccgc
     3841 aacatccaaa tcaccagcca atttttattt ttttaaatga atttttttat cacagtatac
     3901 tccttttttc acttaaaaaa agacttttca gtgattttga cttgcttgaa tccagatcct
     3961 tctaatgttt gcaagatgac gaaagcattg taaagattga tcaaaagaac cacgatgaca
     4021 atcgcttgaa aaataaaggt cacttttttt ggagacaaaa ccctgctaaa tcttgctccc
     4081 cacaaacctc caataacagc agcggggata acataaaaca acatagataa atcaaagcgc
     4141 ataaagctac ttgttaaagc aatcgttacc aattttgcca gttgagaaaa gaaaatcgta
     4201 gatagagaat atagtgttgc ttcttttatt ggcaatgcaa acatcagcat caacaaagaa
     4261 acattgactg gtccaccacc aatacctaaa aaactagcta aaaagcccag aaccccccca
     4321 catataaggt accaagtcca tgacgtcaaa tgaaattttg gctgatgatg cttggtgtag
     4381 aagaacgcaa aaaccaaggt caataccgtc aaaaaaattt ggatcagctg cacatgcttc
     4441 tcgttttcaa ataactgtaa aaaaacttcg aatacaatgt tgccgactac tcctccaaca
     4501 acagctccac tagataccca accgacaatc tgccaattca gtgatttccc gcttgatact
     4561 tgtcgcacag tcgaaacaat ggacatcgtg aataccgcaa ctgttgagta aaaagaaatc
     4621 cctgcaacag aatgggcgcc gataagatca agaatcggtt tgatcaacac gcctccaccc
     4681 atcccggaaa tagcgccaac tgtgttcgcc agaacgatca ccacaaaata aatcagacca
     4741 atcatcttgt atttcctttc tcttgtttat atcttttagc gattgttact cttttctttt
     4801 attatacagt aaaagaaaca aacgaggctt cgaaagcttt tctacttttt aaggaaatt
//
LOCUS       DAXLPY010000117         4686 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.120, whole genome shotgun sequence.
ACCESSION   DAXLPY010000117 DAXLPY010000000
VERSION     DAXLPY010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.120"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            1163..2086
                     /locus_tag="ACF3UF_002601"
     CDS             1163..2086
                     /locus_tag="ACF3UF_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFD3672659.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            2102..2641
                     /locus_tag="ACF3UF_002602"
     CDS             2102..2641
                     /locus_tag="ACF3UF_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFD3672660.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
     gene            3326..3499
                     /locus_tag="ACF3UF_002603"
     CDS             3326..3499
                     /locus_tag="ACF3UF_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672661.1"
                     /translation="MLKKTVLVLGSISLGILGFSPMLLSVIGKNNSNGELKLNSNYYN
                     SPNEELFVKETDK"
     gene            3950..4483
                     /locus_tag="ACF3UF_002604"
     CDS             3950..4483
                     /locus_tag="ACF3UF_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672662.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
     gene            4495..>4686
                     /locus_tag="ACF3UF_002605"
     CDS             4495..>4686
                     /locus_tag="ACF3UF_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672663.1"
                     /translation="MFLISKSLKSLKTFTKKNPQIATIRIFIFAIAVAIIVNMLSGGQ
                     LYKSGLFLVLILVVLDIIKS"
BASE COUNT         1724 a          703 c          841 g         1418 t
ORIGIN      
        1 aaaaaaaaat aaatcgatac attttagaag aatagggttg tttgaatatt acaaagcaac
       61 aatttcacct tcggtgaaat aagcgaaact ttacaaaaag tggctagcaa atgctagcct
      121 ttttttgtat tgtggagcgt ggattttgag ggggattcaa gggggagctt gcgctccttt
      181 gacaagcggt tatttgcacc aaatacggag gtatttggct agcaaatata gagcttgcca
      241 aaccctttta gtgagttttg tagaaagtac ctttaaaggt actttcacat tacgaacgat
      301 acgtccgtag gacgtactga aagggtggga cttatgagca aattaatgca aaatttggct
      361 agcaaaaaag ctaaaaaata tatgctaata atcgagcgaa ataaacactt tttcaagtga
      421 gcgaatccgc catgacaaag ctgaagcagt ttatttcagc tttgtcatgg cgtgtgccga
      481 cttttttaaa agtctaggca cacgagcaaa tatctttatc aagctctaat ttgcgtttta
      541 agacgtttga aacgcctaag tatataaata tataagaata ggtttaagag tgcttaaatc
      601 gaattttaga gggcatttag acaattttag ggttgttagg gcttgccctg accgcctgta
      661 aggcgtttta agaacaagat aagggattta tactaggact gtcttaaaat gtcttaaacg
      721 aacgctcaga gcttctcaaa gggttcctta tgaacggctt ttagcaaagg agccggaggc
      781 gactgcgcag tataatgtga gagcagagcg atcacacctt tttagcgaac cgtagggagc
      841 aaggtttgga attggcagtt ttgataaatt cgcgaacctg tttagagaaa aaaggagtga
      901 ttttttaggc gggaaaatta gcctcccctc tttttatatc tctttttata tctcttttta
      961 tatctctttt atgtcggctg tgtccttact ctcccaagca attcagagtt ttttcaagta
     1021 ggttttctac gcttttcaag taggttttct acgcttttca agtaggtttt ctacgctttt
     1081 caagtaggtt ttccgacatt attgagtatt tttataaagt atgttacttt tatttcatac
     1141 tttataaaag taggagaagc ttatggcaaa tgaaattgta aaatatgaaa atagattaaa
     1201 tcatattcct ctgagaaaat ttaatagtcg tgaaatgaac ttattttttt caattgcttc
     1261 acgtgtacgt gaaaaaggtg tagatgagat tattttttca tttcacgatt tgaaaaaact
     1321 aagcggttat acagaacgtg gggaacaatt tataaaagat cttagtagca cgtatgacaa
     1381 attattaagt attaatgctt ggaatgatga tggaaatact ttaactaaat ttgttgcttt
     1441 cacaaaatat agcattatac gagataaaca acttgttata atttcagtta atccagaatt
     1501 taaaggactt tttaatcaat taaagaactg gacaagattt aatctagagc aatttactaa
     1561 tttggatagc acatattcaa aaactatgtt tcgattatta aaacaatatc gaactcaagg
     1621 ctggactgaa ttttccaaag aaaaattttt tgatttacta gatattccta aaagttattg
     1681 gaatagtccg tcaaatattg acaaatttat cttaaggcca attaaagaag aactcactcc
     1741 cttatttaaa ggattaacta ttcgtaaaaa atatggtaaa ggtcgaggta aacctgttat
     1801 cggttatcgt tttacttgga aagctgaaat taaccatgct gacgattttt ccaaagggaa
     1861 acaagaagat ttacgtataa aattatttaa tattgatcac aatggagaat taacacgaga
     1921 agaaaaatgg cgcgctaaag atcgaatact aaatcttccc ttaggcactc atgaagctga
     1981 ttttaaacaa caacaacaaa ctgaagaaaa acaggcagaa aaacgagaac tttcaaacaa
     2041 actcaaacaa gatttactag gaaatttaca aaacttattc gattaagctt aaggagtatt
     2101 tatggcagat aaaacaatca aagaacttgc ggaagaatta ggagttagta aaacagcaat
     2161 taacaaaaaa gtttctgaca aaaatcgaaa actttggttt gcaaaaaacg gaaacaagtt
     2221 tgtgattaac gaaaccggtc aaaaagctat aaaatcaatg tttttagtcg ataacgcaaa
     2281 cttaaatcga aaactagttg gcgaaaaatc aaaaaccaaa aaccataaaa acaccaacca
     2341 agtttccgaa ttaaaactcc tttctttcct agaaaaacag ttaaatcgaa aagatataca
     2401 gctacaagaa aaagataatc aaataaaaca aatgcaaaaa ttactcgacc agcaacaaca
     2461 actcactcta caagcgaacc aacaaattga gaacctacaa gaacagctcc atttaactta
     2521 tacagaagaa actccaacaa ccgaatcaac tgccttttct gaaaaaaaag cagacaatac
     2581 acaaccactt attgaaaaaa agtggtggca aatttggaaa tctaatagaa ccaatctcta
     2641 aaattttcta gaagttagtt cggatagtag aggaaaaagt tgtactacct gatggggaga
     2701 tcactcaaat ttttatgaga aagaaaaaat agtttacaac tgtaaacaat caatgtttat
     2761 agttgtaaac tatcaaacta tatggtgact tattgcttaa aataggttga aatctcactc
     2821 aatttttggt ggaaaaacaa aataaattct aatcgatttt gttgaaaaag tcataaaaaa
     2881 acaaatgtga ttttaacaaa atttcaaaaa aatcgtttga aatttcgttt attttttttg
     2941 agaattttga tcatcgtagg gtcattgtag aatcattatg agatcatcgt gggatcatcg
     3001 aataaagtat gggaaaggct tgcggtgctt ggtattaagg gcattctccg cctcccaggt
     3061 tcttgaccat tttctctcaa cgtggtaaaa atcccactta taagagaaaa tggtcaagaa
     3121 cctaaacggt cggcgaagaa aacataccaa gcaccacaag caaaaaaagt tagagtaact
     3181 tccaaaaaag aaaaattttt tagaacaact tttgaaaatt taattttgat ttatatccgt
     3241 tcaatttaaa catttgataa actgaaggct agtatttaaa atgtgtatac aagtggtagc
     3301 gttaaaaaaa gtggaggtat aacctatgtt aaaaaaaact gtgttggtac tgggttctat
     3361 ttctctagga atattaggtt ttagccccat gctattatcc gtaattggaa aaaacaattc
     3421 caacggagaa cttaaattaa attcaaatta ttacaacagt cctaacgaag aattgtttgt
     3481 aaaagagacg gataaataat aaaaaagact gctctttcga gcagccagtt aaaaaataat
     3541 gagtgtttat tcttgaaaaa gcaacgcgct tatgaagcgc taccaaaaat ttatcatatt
     3601 ttatgaaaaa taacacccca gtaaaaaatg actggtaaaa attcacaaag aaacggaaag
     3661 aagcaactgc agaaaatcaa gccttaaaaa gagcttttga cttagaccaa tcgaaaatca
     3721 caaagtgagc ccctgtatcc cttggtagag aggctacttg gcatagtaca cattatgtca
     3781 acaagaattt aatataacat attttcctaa tgcattctaa ctataccaca ttatcaaaaa
     3841 tataaattat ctttactaaa taaaatattg acaagcctat accttttgtt ttatgatttt
     3901 cacaaagaaa acgttttcta tatatttttc tgtatcagga ggaaattcta tgaaaaaatt
     3961 tactttaggg gtagctttgt taactattgg ggcagttgtt ttaccgtcaa ctactatagt
     4021 ttatgcttca gaaaattccc aagtggtatc attaaacgaa aacaatgcta ctgaaaatgt
     4081 agttattgag tacactgaag atggtatggt cgtaactaaa tatgaggatg gttatagtgc
     4141 ggaagatttt gcaaattctt cagatatcat gacaagagct gcagttgcaa gatggggcaa
     4201 aaaggaatat acaaatattg ctgtaaccac tggagtagct gctaatgcta ttaatgctgc
     4261 cttttgggca ggagggaaag ctagcacttc tatgtttggt atcccaggtt gggcaattgg
     4321 tgctttgtta acaggtgcaa gttggactaa aaaaggtgct tctccaggga atgcagttgc
     4381 aaaagaatgg gacaaaaatg gtaatggctg gattggattt tattaccaaa ggggatatga
     4441 tgcagctgga agagttgtag ctactagata ttcaacgtta taagttaagg agtgatgttt
     4501 ttgatatcta aatcattaaa atcattaaaa acatttacta aaaagaatcc gcaaatagct
     4561 actattcgta tttttatatt tgctatagct gttgctataa ttgttaatat gctaagcgga
     4621 gggcaattat acaaatctgg tttattttta gtgttaatct tagttgtctt agacataata
     4681 aagtct
//
LOCUS       DAXLPY010000118         4616 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.121, whole genome shotgun sequence.
ACCESSION   DAXLPY010000118 DAXLPY010000000
VERSION     DAXLPY010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.121"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..344
                     /locus_tag="ACF3UF_002606"
     CDS             <1..344
                     /locus_tag="ACF3UF_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde
                     dehydrogenase"
                     /protein_id="HFD3672664.1"
                     /translation="KAKNLVSLQNGTISPLQMASQAVKKFGTVQVTGVYMTPASSYPL
                     QEFFMRDIAVKHGQAPIIHLMPKIYEMIAEGLFDPTQIITHSLPLSEAAQAYEIFDKK
                     EDKNIKVVLKP"
     gene            375..695
                     /locus_tag="ACF3UF_002607"
     CDS             375..695
                     /locus_tag="ACF3UF_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFD3672665.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(724..1188)
                     /locus_tag="ACF3UF_002608"
     CDS             complement(724..1188)
                     /locus_tag="ACF3UF_002608"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3672666.1"
                     /translation="MVTYNWIKLREHPELVKQSAKWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(1317..2566)
                     /locus_tag="ACF3UF_002609"
                     /pseudo
     CDS             complement(1317..2566)
                     /locus_tag="ACF3UF_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(2595..2912)
                     /locus_tag="ACF3UF_002610"
     CDS             complement(2595..2912)
                     /locus_tag="ACF3UF_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3672667.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(2938..3258)
                     /locus_tag="ACF3UF_002611"
     CDS             complement(2938..3258)
                     /locus_tag="ACF3UF_002611"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3672668.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDIINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(3659..>4616)
                     /locus_tag="ACF3UF_002612"
     CDS             complement(3659..>4616)
                     /locus_tag="ACF3UF_002612"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3672669.1"
                     /translation="DRYGDRVKNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNY
                     HKVLATAKAVEIYRSGNYGGRIGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDP
                     MVKGYYTEEFLELCQKQSIYFDPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNE
                     ETPFHPERYYEVFDLPGKKMNNSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGR
                     EHEERYMDEKGIVQDDYRIEFIGQHLRYLIKATEEGANCEGYMLWAFTDCVSPMNAFK
                     NRYGLVRIELNDERSRTLKKSASWYQTLIDKRELDLPDEIYK"
BASE COUNT         1427 a          968 c          768 g         1453 t
ORIGIN      
        1 aaaaagcgaa aaatttagta agcttacaaa acggcacaat ctctccatta cagatggcat
       61 cgcaagctgt caaaaaattt ggaacagtcc aagtaactgg tgtttatatg actccagctt
      121 cttcttaccc gctgcaagaa ttttttatgc gggatatcgc tgtcaagcat ggacaggcac
      181 caattatcca tctaatgcca aaaatttacg aaatgattgc agaaggacta ttcgatccta
      241 cacaaatcat tactcattcg ctgccactat cagaagcagc acaagcatat gagatctttg
      301 acaaaaaaga agataaaaat ataaaagttg ttttgaaacc ttgaattcag taaaaaatac
      361 aggtgatttt ctttatgccc aaaatcaaac gaaataccca tgagatcgaa ataggaaaag
      421 aagaagatat cgaaatacga ggacgtcgct tccgcttcta tttccaaaat cgttacacat
      481 tgatctcact ggctgtcgat ttattaaccg ggattttcta tatttttgga agccttgctt
      541 ccttaactaa aatccccgat cgatatggca cctattttta tttggctggt gctattttct
      601 tgacgattcg tcctattctc agaatcgtaa ggaacatttt tatttacgac gaaaaaaaag
      661 caatgaagag aacaagcaaa aaaaaagagg catgagattt gaaaaaatct catgcctctt
      721 ttttcaccct atcgtatcac tttgatacag acgagcggtc gtcccacttt cttccttgac
      781 cattgtcaaa aatgtccact cgtatcgttc ataaaacgtg gtatgatctg taattaagta
      841 aagtttttcg tacccaagtt gatgcatttc ttttctgatt tccgctaata tccgcttggc
      901 tatcccctgc ttacgctttt ccggttcaac aaacagggca caaagatttg gtgtcaaatc
      961 agggcggtta tggaagtcgt tttcaataac gcccgctcct ccgacgatgg tttctttttc
     1021 atctaagacc acataccatt gaggaatact ttccttatta gcgattccag tacgaatact
     1081 ttcctcatac acaacagcag gaactcccca ttttgatgaa aaccacttcg cactttgttt
     1141 tactaattct gggtgttctc ttaatttgat ccagttatat gtaaccaatg tttaaacctc
     1201 cgactaaaat aaaacgttta caaaaattat acaagtcttt atgaaaatta gcaatgacaa
     1261 caatagtgat gtaaaaaaaa cggaaaacaa tcacttgttc tccgtttttt gattaatcaa
     1321 gcatctaaag cttcttttct tctttcttgg atcgtagcta ccttgacgaa cggtagatag
     1381 atcaaaatag aaagaaccaa attgacagcg gctagtacac cacctgcaat actttttgtt
     1441 gccaatacac cgccaataat tggtggagtt acccatggag gcataacggt agctgctggc
     1501 actaaacctg tagaagtcgc aaagtaagca acactaacta agaccattgg tgtcaaaata
     1561 aatggaatga acatgatcgg gttcaacacg ataggtaacc caaacatcgt tggttcatta
     1621 atattgaaga cacctggcgc aatcgacaag tttgttacaa ccatatatgg tttgttttta
     1681 cgtcctacta aataaatagc taacagtaaa cctaaagttg cacctgttcc tcctaagttg
     1741 acaaagctgt caaagaaagg tttgttcacg ataaacggtg cgctatgtcc agctgcgatt
     1801 gcattaacgt ttgcttcaat ggctggcgca ttgattgttt gcatcaaagg atcgaccata
     1861 ttcgctccgt gtaaaccaaa gaaccataag aatggtgtga taaatgcaag cagtaaggca
     1921 gatggataag agtttgcaag tcccataaat ggttcttgga ccactgtata gaaagaacct
     1981 acgatatcat caacaccgaa tgcagcaaaa attgcagcaa ctaaagcaaa cgcagagata
     2041 gtgatcattg ctggtagtaa tgaagcaaat gcttttgcaa ctgccggtgg cacaccatca
     2101 ggcattttga tgatcaattt ttcatttccg cttaaacgta caaagatttc tgttgaaata
     2161 atcccaacaa taatagcaat aaataaaccg tttgagctca tacctaatgc tccgcctaaa
     2221 gcgaagaaag agcctaaaga aatcacacct gcggaaacac cgtcttttcg gtagccgtta
     2281 gctaaatgat aagcaagaaa gcaatcaaga cagaaagaat ggcaaatgta ccgttccaag
     2341 cagcagcccc gaatcctttc catgattcac caccaaaaat tgagttcatc aattcttgga
     2401 acccgggaat cggtaagtta ttgatcatta ctgctaatgc tcctaagatc attaacggca
     2461 tactcaccat aaatgagtcc cgaatcgcaa ctaaatgccg ttgtgcacca atttttgatg
     2521 ctacaggtat aaaatgtttc tccataaatg caacaaattt atccataaat cttccctctt
     2581 ttctttactg tagattacgc gttcaatcga cgatacagat caatgatctc ttttgctaaa
     2641 tctgtaaaag ctatggatgt catcagatga tcttgactgt ggactgtcaa aagcgtgact
     2701 tcaacgtgat ttccttgtgc ttcttgtgtc agcatctctg tttgagagtg atgtgcttgg
     2761 actaaagatt cctctgcatc tttgattttt tcatctgcta aagtgaaatc accttttttc
     2821 gcagcagcaa tcgcttccat tgcatcgctt tttgcatttc cgccaaacat gatcagaccc
     2881 atgatggctt ctagattttt ttgatcttcc atttattgta tcctccgata atttttatta
     2941 tttgtttatt agtttttctg cttggtcgag tactttttca ccattcatca tgccatagtc
     3001 agccatattg attatatcta aaggaatgcc tttaggtgct agcttttcag caaattgatt
     3061 ttgcataaag cgtacttgcg gtcctaaaag taaaacgtct acatttttag attctagttg
     3121 attatccgca tctgaagcag atacagcaaa gatgtctgct tccattcctt ttgcttctgc
     3181 tgccttttgc atttttgtga ctaggagact tgtactcatt ccagctgaac atacaagcat
     3241 gattgttttc ttttccattt taaacacgtt cctttctata cttacacttg tatataagca
     3301 agtagcgtgc caactttgaa agcgctttaa aaagttgata tcatcacatt taaggtctat
     3361 accaagttgc atacacacta aaaaagaaag tgcacactaa acacacaaat taatttttat
     3421 tacctttttt cttttaacgt gcacaaaaaa agttgtgaca caaaacttgt cacaactttt
     3481 tttcgaataa acggtattca aaagcttgca tctgcggtaa taagtccaac caagttaaaa
     3541 acataagatg ttgtttttac tttgctattc ttattacttg atgcaggaca gctttttcac
     3601 aacctctttt atttcaaata accagtaaat acaatgaaca tctacaaaaa acttctattt
     3661 atttatagat ttcgtcaggc aaatccaatt ctctcttatc aatcaaagtc tgataccacg
     3721 aagcagattt tttcaatgtt ctgcttcgtt catcgttcaa ttcgattcga actaatccat
     3781 atcgattctt aaatgcattc attggtgaca cacagtcagt gaatgcccat aacatatagc
     3841 cttcgcaatt tgcgccttct tctgttgctt tgatcaaata acgcaaatgc tgtccgataa
     3901 attcgatacg gtaatcatct tgcacgattc ctttctcatc catataccgt tcttcatgtt
     3961 ctcttcccat accgttttct gttatcagcc aagggatatt atgataattt tcttttagat
     4021 acatggctat atcatacatg attttcggat agatttccca tcccctggaa ttattcattt
     4081 tcttcccagg taaatcaaag acttcataat atcgttctgg atggaaaggt gtctcttcat
     4141 tccattgata acgaggagcg cgaacgcgtt taggataata ttgattgatt ccaaggaaat
     4201 ctactgtatg atgctgaatc gtttctaaat cctctgttgc aggatcgaaa taaatcgatt
     4261 gtttttgaca caactccagg aactcttctg tgtagtaccc ttttaccatc ggatcaaaaa
     4321 atactcgatt ataaaacaaa tcatacatat aagcagcttt ttggtcttct ggagaattag
     4381 atcgagcata gaccatttca ggatttaaaa tacagccaat ccttccacca taatttccgc
     4441 tgcggtaaat ctctactgct ttagccgttg ctaaaacttt atgataattc cacatcatcc
     4501 acttttttgt gttttgttca tgcggccagc gaacagcatc caaatagcaa cgcgtttggg
     4561 gaacgattgg ttcgttgaat gtaaaccagt tttttaccct atcaccgtaa cgatca
//
LOCUS       DAXLPY010000119         4528 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.122, whole genome shotgun sequence.
ACCESSION   DAXLPY010000119 DAXLPY010000000
VERSION     DAXLPY010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.122"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            258..755
                     /locus_tag="ACF3UF_002613"
     CDS             258..755
                     /locus_tag="ACF3UF_002613"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HFD3672670.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDR
                     ERMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTN
                     SASGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLK
                     EKVVR"
     gene            756..1172
                     /locus_tag="ACF3UF_002614"
     CDS             756..1172
                     /locus_tag="ACF3UF_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HFD3672671.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            1192..2736
                     /locus_tag="ACF3UF_002615"
     CDS             1192..2736
                     /locus_tag="ACF3UF_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672672.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            2879..3103
                     /locus_tag="ACF3UF_002616"
     CDS             2879..3103
                     /locus_tag="ACF3UF_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672673.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            3118..3987
                     /locus_tag="ACF3UF_002617"
     CDS             3118..3987
                     /locus_tag="ACF3UF_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFD3672674.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3968..>4528
                     /locus_tag="ACF3UF_002618"
     CDS             3968..>4528
                     /locus_tag="ACF3UF_002618"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3672675.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKV"
BASE COUNT         1593 a          726 c          987 g         1222 t
ORIGIN      
        1 tttaaagtat tctgcttcat cacccattag gtgatgaaaa aagaacccct ttctgattta
       61 gcggacaaat actttgacct aatctcagaa gatataaaag aaaaaataat aaaatatccg
      121 atttatactt tgtataaaga actaaagtag ttagcaaatc atttacagca aatcactatg
      181 ttccacatac cattttacat acttacctta tccacgacac atgttgagat agtatcgaag
      241 ataaagaaag ttgctccatg ttgtttttgc gagatgggga aatcaaagcc acattgacaa
      301 ccatgatgaa taagcttgct ttcagtcata agctaatcct agaaccactt ttcaagtcag
      361 ttagccaaat cgatgaagaa agcgaccgtg aaagaatgga cgctattgat aagctaatgg
      421 agcaactatt ggaagaacgc aataccctta ttgcactgat gtccaaaggt ttcctagaac
      481 ctgctctttt taatcaggaa cgaaatgttt tagatagtga gattaaaaat cttactaccg
      541 aaaaaacaaa cctggtaacg aactctgcga gtggggtttt gcgagcaaac gagataaagg
      601 acctcattaa ttatgtgtca gcagataatt ttaatggtga ctacacggaa gaactatttg
      661 aagaatttgt agtgaacatc attgtaaatt ccagggatga gctgacattc aatttgaaat
      721 gcggtctttc cctgaaagaa aaggtggtga gataaatggc atatattcca tatggataca
      781 aaattcaaga tggagtggtt actgtcgatg aaaaggcagc aggtcaagta aaggtattct
      841 ttgagaaata catatcagga ctatccctta cagtggctgg cgaacaggca ggtattgaaa
      901 agacacattc tgtgatgggg cgcattttga aaaacgtcaa ctaccttgga aatgatacgt
      961 atccagcaat tattgataaa gagatatttg ataaagctga agaagttaga gataaacgtg
     1021 caaaggattt aggacgagtg gtagagcttg ccgctttcac ctctccccct cccaaagaac
     1081 gattcaaaat gaaaaaggca gataataaga tgccagtgga tccttttgaa cgagcagaat
     1141 acttatacag tctgatagaa agcgaggaat aaagtgacag agaaaaatat aatggttatt
     1201 cctgctcgta aaagagtagg aagtacagcc gcaaaagaaa agataaagaa acttcgtgtt
     1261 gctgcctatt gccgtgtttc tacagaaaca gaagaacaaa attctagcta tgaggttcag
     1321 gtctcacact atacagagtt tataaagaaa aataatgaat gggagtttgc tggcatcttt
     1381 gcagatgatg gtatctctgg tacgaacact aaaaagcgtg acgaatttaa tcgcatgatt
     1441 gcagagtgta tggacggtaa catcgacatg gttattacaa aatccatcag ccgatttgcg
     1501 cgtaacaccc tagactgcct tcaatacatt agacagctca aggataagaa catatcagtt
     1561 tattttgaga aagagaacat caacaccacg gatgccaaag gtgaggtttt gctgactatt
     1621 atggcatctt tggcacagca ggaaagccag agcctttcac aaaacgttaa gcttgggcta
     1681 cagtaccgat accaacaagg aaaggtgcag gtcaaccata agcgatttat gggctacacg
     1741 aaagatgaag atggaaattt aactattgtc cccgaagaag ctgagattat caaacgcatc
     1801 taccgagaat accttgaggg tcagagtcta gtgggcattg gtcgagccct tgaaaaggat
     1861 ggtattttaa cagcagcggg aaaaccaaga tggcgaccag aatcagttaa gaagatactt
     1921 caaaacgaaa aatacatcgg agatgccctt ctgcaaaaga ctgtcacagt agattttctg
     1981 accaagaaac gagtgaaaaa tgaagggcat gttccccaat attatgttga aaatagccat
     2041 gaagcgatta ttcctaaaga gttatttttg caggcgcaag aagaaattca tcggagaagc
     2101 aatatctaca caggagaagg caagaacaaa agaatttaca gtagcaagta cgctttaagt
     2161 gccatcacct tctgtggaga ttgtggcgat atttatagac gggtctattg gaatatccac
     2221 ggaagaaaag aatttgtctg gcgatgcgtg actagaatcg agcaaggtcc tgaagtttgt
     2281 aagaaccgaa ccgtaaaaga agatgaactt tatggtgcag taatgactgc gattaataag
     2341 ctacttgcag gtgggaacaa tatgataaag acactggaag agaatattca tgctgtgatt
     2401 ggcgaaacca cagaatacca aatttcagag attaacaact cactagagga aaaacaaaaa
     2461 gaactaatca agctggcgaa caagggtcaa gactatgacc acttagcaga tgagattgat
     2521 gagctgagag acaagcgaca gatcctttta gtagaagatg cctccctcag tggcgagaac
     2581 gagcgaatca atgagctgat tgaatttatc cgcaagaaca aattccgcac cttagaatat
     2641 gatgataagc ttgtaaggaa gataatccag agcgttacag tctatgaagg ccacttcgtc
     2701 atagccttca aatctggcat cgaaatggaa atatgaaaac cagaagtaaa tagcccatga
     2761 ctctacagta gagttgtggg ttttcttttg cttgctgatt ataataatat tttaataact
     2821 attgtgttta tcaaccaaat ggtttataat attcttagcg taaacttgga ggtgctgtat
     2881 gactacggca gaaatgatta aagaactgtg tgagcaaatg aatataagtg tttccgaact
     2941 tgctagacgt attggccaga ctccacagaa tttcaataaa aaattacaac gagaaacagt
     3001 aaccttggat gagttgaagg ccattgctga tgtgctaggt gtcaagtttg tgcaggcatt
     3061 tattttacca gatggagaag aaataaaaat atctaacgaa taaaggagga tgtttatatg
     3121 gtaggtaatg ttattcaaat agtaacagag aaattatcat ctttgccttt tatagaaggc
     3181 atcgtattag ggggctcacg tgcaagaggc acccatacag aaaattctga tatagatatc
     3241 ggaatctatt acaattcaga ctcatttgac ctgacagcga ttaatcaaat tgctacagaa
     3301 ttggatgata aaaatagaaa caaccttgtt gtgcctcccg gagcgtgggg tgattggatt
     3361 aatggcggcg gatggttatt tataaatggg tatcatgttg acttgatttt acgtgatata
     3421 aaacgggtag aacaaataat caaagatacg gagcaaggaa ttgttactgc caattatcag
     3481 accgggcatc cccatggtta tataagtgca atgtatcgtg gagaattagc gattagtaaa
     3541 atactatatg ctaagaacga aagcttatgc gaattaaaaa agcaggcaga aatttaccct
     3601 actgctctaa agaaaagctt gatgaacttt tttatatttg aagctgaatt ctctttaatg
     3661 tttgtaaaag caaatgcggg ggtagaggat aaatattata ttgcaggcca tgtttttcgt
     3721 attatttcat gcttaaatca agtactattt gcatgtaata atgcttattg cattaacgaa
     3781 aagaaagcta taaaactgct tgaaactttt gaatataaac ctgaaaaata tgccgaaaga
     3841 gttaatcata tttttgaagt actcggtctt tctctttttg aatgctacga tatgaccgag
     3901 aaactttata aagaagtgaa tgaaattgta tcggagataa ataacttttt aaacgaggag
     3961 agttcagatg aaagaaaaca aatatgatga taatatattt tttcaaaaat acagtcaaat
     4021 gagtcgctcg cagaaaggac tggctggtgc gggagaatgg gagactttga aaaagatgct
     4081 acctgatttt aagggtaagc gtgtgcttga tttaggatgc ggctatggat ggcactgtat
     4141 atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt gatatttctc ataaaatgct
     4201 cgaagtagca aaaggaaaaa cccattttcc acagattgaa tatgaatgct gtgccataga
     4261 agatgtggat ttcccagagg agagctttga tgtaatacta agttcgcttg cgtttcatta
     4321 tgtagcagac tatgagaatt taataaaaaa gatatatagg atgctgaagg ctggtggcaa
     4381 tttagttttt acagttgaac atcctgtttt tactgctcat ggaacacaag actggtatta
     4441 taacgaaaaa ggagaaatac tgcatttccc ggtggacaat tattattatg agggcaaacg
     4501 gacagctatg tttttggaag aaaaggtt
//
LOCUS       DAXLPY010000120         4431 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.123, whole genome shotgun sequence.
ACCESSION   DAXLPY010000120 DAXLPY010000000
VERSION     DAXLPY010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.123"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            86..1507
                     /gene="gndA"
                     /locus_tag="ACF3UF_002619"
     CDS             86..1507
                     /gene="gndA"
                     /locus_tag="ACF3UF_002619"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFD3672676.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            1700..2386
                     /locus_tag="ACF3UF_002620"
     CDS             1700..2386
                     /locus_tag="ACF3UF_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3672677.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            2383..3888
                     /locus_tag="ACF3UF_002621"
     CDS             2383..3888
                     /locus_tag="ACF3UF_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3672678.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
BASE COUNT         1544 a          729 c          921 g         1237 t
ORIGIN      
        1 atgttgttct ttagtttgca atgtagccgt gttaagctat aatgtaagag attagggaga
       61 aatcccgtat gtaggaggag ttcatatgtc aaaacaacaa atcggcgttg tcggtatggc
      121 cgttatgggt aaaaatctag ccttgaacat agaaagccgc ggctattcag tggctttatt
      181 caatcgtaca ggggctaaaa caaccgctgt agtagaagaa cacccagata aaaatttcaa
      241 agcaacatat acaatcgaag aatttgtaga atctatcgag aaaccacgtc ggatcttgct
      301 aatggtcaaa gcaggaccgg caacagatgc aacaatccaa gagttacttc ctcaccttga
      361 taaaggcgat attttgattg acggaggaaa tacattcttt aaagatacga tgcgtcgtaa
      421 tgaagagtta gccaactctg gcatcaactt tatcggtaca ggcgtttccg gtggtgaaga
      481 aggagcttta aaaggacctt caatcatgcc tggtggacaa aaagaagcct atgcgctagt
      541 tgcaccaatc ttagagcaaa tttctgcaaa agcagaagac ggagcaccat gtgtcacata
      601 tattggccca aatggagccg gacattatgt gaaaatggta cacaacggta ttgagtatgg
      661 agatatgcaa ctgattgctg aatcttatga cttaatgaag aatattttaa acctttcagt
      721 agaagaaatg gctgatatct ttaaagaatg gaatcaaggc gaattagaca gctatttgat
      781 agaaatcact gctgacattc tgacacgtaa agacgatgaa ggaacaggta aaccagtagt
      841 agatgtgatc cttgatgcag ctgggaataa aggaacaggt aaatggacaa gccaaagcgc
      901 gcttgactta ggtgtgccac ttccattgat cactgaatct gtatttgccc gctatatttc
      961 tgcttataaa gaagaacgcg tacaagcaag caagattttg tctcgtacga acgattttga
     1021 gttcacggga gacaaaaaag aattggtcga aaaaatccga gaagcgttgt atttcagtaa
     1081 aatcatgagt tatgcccaag gatttgctca attacgtgtc gcttcaaaag aatttgattg
     1141 ggacttgcca tttggtgaaa tcgcaaaaat ctggcgcgct ggatgtatca tccgagctcg
     1201 attcttgcaa aaaattacgg atgcctatga caaaaatcct gagatcgaaa atttattgct
     1261 agatgattac ttcgttgaaa tcacgaaaaa atatcagcaa tcagtcagag acgtcgttgc
     1321 cttggctgtc caagctggcg tacctgtacc gactttctca tcagccatcg cttacttcga
     1381 ttcatacaga gcagaacgtc tgcctgcaaa tataatccaa gcccaacgcg attactttgg
     1441 cgcacatacc tatgaacgtg tcgacaaaga aggaatcttc cattactcat ggtaccatga
     1501 agaataatag tctttcggct gttaggaaat gagaaaataa aaagaggacg aaagagctga
     1561 agtcgattgt tatgagtaga cttcagctct tttttaaaat tgctatccat gataaaatga
     1621 ctatagattt ttaagcatat tatcggtata atgatagagt ttttaaaaag ccagtagaat
     1681 agaaaggata aaataataaa tgagcaatat tctaatcatt gaagatgaaa agaacttggc
     1741 acgatttgtc gagctagagt tgaagcatga agggtataac gcagaagtcc actacaacgg
     1801 ccgaactggt ttagatgcgg cattaaataa tgagtgggat gccatattgt tggatctgat
     1861 gctcccagaa ttgaacggtt tagaagtctg cagacgtgta cgccaagtca aaaatacacc
     1921 aatcattatg atgactgcaa gagattctgt gatcgatcgt gtatctggac ttgaccacgg
     1981 agcagatgac tacatcgtca aaccatttgc tatcgaagaa ttattagcac gtcttcgtgc
     2041 attgttgcgt cgaatcgata ttgaaggcga taaaaatgtg gctaaacaaa ctactattac
     2101 ttatcgcgat ttgactatcg aaaaagaaaa ccgtgtcgta cgtcgcggaa atgaagtaat
     2161 tgaactaaca aaaagagaat acgagttgct gcttacttta atggaaaacg tgaacgtggt
     2221 attagcacgt gacgttttac taaataaagt gtggggatac gaaacagaag ttgaaacaaa
     2281 cgtagtggac gtatatattc gttatcttcg caacaaaatt gacgttcccg gggaggaaag
     2341 ctatatccaa actgtacgcg gaacaggtta tgtgatgcgc tcgtgataaa gccgaaaaaa
     2401 tcggaaaaaa gagaactgaa agggccctcc ttgacaatca agtgggcctt tgcgagttct
     2461 ttcttcatat tcgttgtgtt tacaattttc gctgtcatta cctataaatc atctatcaat
     2521 ctgattgtgg caaaagaaag aaacaatgta gagcgtacga tttcagaagt agcttctcgt
     2581 ttggctaact cggatgaaga actgacatta gtaaatacgt atcgtaatct gacgaaagcg
     2641 acaaatgacg gagatgaggt cgtagatcat acttcactgg tcgaaggaaa cttaatgaag
     2701 atcgattcct ttatagctga gctagggcag ccatcaatgg atctttatgt ttatgatttg
     2761 gacgagaact tgatttttaa aacccatgaa aacagtcgaa acctgattca gactacacgt
     2821 aaagttccaa cgatcgttac actagaagga aaaactggct ttttatctat ccagcctata
     2881 tattctaaag gtacaagaga aaagatcggc tatgcgcaaa gcttctatga attatcttct
     2941 ttctatgata ttcgaaataa gctattattg actcttattg ttttagaagt tgtttctttg
     3001 atcttaagta gtattttagg tttcttttta tcttcttatt tcttaaaacc actcaaggta
     3061 ctcagagata caatggatac tatacgtaaa gatccgcaat cagatatcca catgcctgaa
     3121 atcgacacaa atgatgaatt ggcagattta gctgaaatat tcaatgagat gcttgaccgt
     3181 atgcgtttgt atattgaaca acaagagcaa ttcgtggaag acgtatctca tgagttaagg
     3241 acacctgttg caattattga agggcatctt agtctgctaa atcgttgggg gaaagatgat
     3301 cctgagatat tagaagaatc attaagcgcc agcatgcaag aaattagccg tatgaaaagc
     3361 ttagttcaag agatgctaga cttatcaaga gcagaacaag tagatgttca ttatgcgaat
     3421 gaaacaacta aaggaaaaga agtcacctat caagtttata ataatttcaa gatattatat
     3481 ccagactatg tgatcacttt agatgatgat ttgacaaaag aagtgaccct gcaaatttat
     3541 cgtaatcact ttgaacaatt aatcattatc atattggata acgcagtaaa gtattcaact
     3601 acacgaaaag aagtccatat ctctatttct tccactctga atgaatttga gatcgcgatt
     3661 caggactttg gcgaaggaat acccaaagaa gaccttaata agatcttcaa tcgtttttat
     3721 cgagtggata aagcaagagc tagaacgaag ggtggaaatg gtctggggtt gtctatcgct
     3781 aaacaactgg ttgaaaacta taaaggacgt atcttagcag aaagtgtagt agggcaaggg
     3841 acaattttta gaatctttat tcctatcgca aaggcagaag acaagtaaag catgtgcttt
     3901 acttgttttt ttatatatcc aacaaagaat aaggtacaaa atacaagcaa gttagaaatt
     3961 cagggatgtc attataaaaa aaactagcga acaattaaat agaataacat ccgttaatta
     4021 aacgtaagta gcttttagat gaacgaaaaa acaatgaaat gctgtaatat tcgtgtttaa
     4081 aaataataaa taaaaatagg gaattttcta ttgcaatttt ataaagagat tgctatatta
     4141 ttatttgttc taaatgattc ctttaaggtg tcactaaaaa ttataaaaaa tagggttgac
     4201 gcacttttga tgtcatgtta taataacgaa gtcgtttgga tgaggtagct aataaagctt
     4261 gattttatcg aaaaaaactt cgaaaaagtt gttgacaaat aacaataaag atgatatgat
     4321 aatcaagtcg ctgctaatga gtgacaaaga cgtttagaaa aaataaacaa agaagttgtt
     4381 gacattctct tctgaatctg ataagattaa agagttgttg aaacaaaaag a
//
LOCUS       DAXLPY010000121         4418 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.124, whole genome shotgun sequence.
ACCESSION   DAXLPY010000121 DAXLPY010000000
VERSION     DAXLPY010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.124"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            61..915
                     /locus_tag="ACF3UF_002622"
     CDS             61..915
                     /locus_tag="ACF3UF_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFD3672679.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1012..3261
                     /locus_tag="ACF3UF_002623"
     CDS             1012..3261
                     /locus_tag="ACF3UF_002623"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFD3672680.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3264..>4418
                     /locus_tag="ACF3UF_002624"
     CDS             3264..>4418
                     /locus_tag="ACF3UF_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3672681.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1557 a          625 c          806 g         1430 t
ORIGIN      
        1 atgtaataat ataaacataa taaaacaaaa attatccaaa tctaacatag gagggtggat
       61 atggaaaatt ctatatattt agtaacagaa cctaacactc agctgaaaga ttgttacttt
      121 aatttttgtg ggtattcaaa aacagaacct agacatagtt ttggaccagc tattcgagaa
      181 caatacttaa tacacatagt gctagaaggt gaaggctatt attcaattaa tgatcaaaaa
      241 tattttctga agaaaggcca aggatttgtt atcccaccag gagtatctac tttttatcaa
      301 gcagatgaaa aaaatccgtg gtcatatgta tggttgggtt taagtggcaa tcttgtagaa
      361 tactatctaa aagaaattgg tgttggaaag aatcatctta cctttaaagt cgaaaattta
      421 aattcattta aaggattaat ttttgaaact ttatcgtatg atcaggacaa tctagtcagt
      481 gaattgtcca gacaaaaaca agtttataaa tttttagaac tcctcttaaa ttcagctagt
      541 tatctgaacg aagggataat tactaaaaag atgaatcctt ttgttcgtca aacaattgaa
      601 ataatacgtg agaatgcgta tcaaaaatta tctgttaaag atattgctgt cagtctatcg
      661 atacacgaaa attatttatc acgattgttt aagaatgata tgggaatatc aataaaagag
      721 tatattagtg aaatcaaaat ttctattgca aacgatctgt tatcatcaac tgaatattca
      781 atccagcaaa tcagtgacaa gataggattc tcaacagtac aatctttttc taaagccttt
      841 aagaaagcaa atggtgtttc accgggagta tatcgaaaac gtagattagg tctaggaatc
      901 attaatggtg aataaactaa acatttgatt ttgataaata ttcgttactt taaacgctta
      961 ctatttatgt gagcgttttt tataatgcaa taaagaaacg gaggagagct tatgtataag
     1021 gataatgaaa tgaatattat ttatcgatca gaaaaccaac aatttcattt gtttaatcag
     1081 gagataagtt acatttttaa gatatcggaa gatggtaaat tattgcattt atattatggt
     1141 gagaacttac cagataatga ctatagtcat ctaattgaga tgcatcatcg gcctatgaca
     1201 acctatagaa atgaaaacga tttgctatat tcgttagagc acttaaaaca agaatttcct
     1261 gaatatggta caacagattt tagacatcct gctatttcat tactacagaa aaatggctct
     1321 cgcttatcag attttgtcta tcaagggtac gaagtggaag aaggaaaacc taaactagaa
     1381 ggtttacctg ctacctatgt tgataataat gatgaaagca aaacattgaa agtttatatt
     1441 ttagattcag ttacaaatgt tcaagtagaa ttattatata caatttatag agattatcct
     1501 gttattactc gtagcgcgcg agttatgaat aaaggaaaag atattcaaat aatcgagaat
     1561 attagcagtt tatcattgga tttacccgat gcaaattatg aatggcaaca attatctggt
     1621 gcttggggta gagaaagaac tattaagtcg cgtactttac aacaaggaat tcaatcaatc
     1681 gaatctactc gaggtatttc aagccatcag cataacccat ttgttacttt aaaaagaaaa
     1741 aatactgatg aaaatcaagg agaagctatt ggtgcagcac tagtttactc aggaaacttc
     1801 ttaattcaag cagaagtaga tacatgggat gttactagac tacaagttgg catcaatcca
     1861 tttggattta attggaaact caatccagga gaaatattta cagcaccaga agcgattctg
     1921 gtttattcaa gtaagggttt aaatgccatg agtcaaactt ttcatcaact atttagaaaa
     1981 cgcttagctc gtggtaagtg gcgagaaaaa gaccgtcctg tcttaattaa taattgggaa
     2041 gcaacatatt ttgattttga cgaagaaaag ttggtaaata ttgctaaaaa agcatttgat
     2101 gttggtattg aattatttgt attagatgat ggctggtttg gagaaagaga aaacgattgt
     2161 gcaggattag gagattggca tgtaaatcct aaaagactac ctagaggaat cggcagcctt
     2221 tcagaaaaaa ttcgtagttt tggtatgaaa tttggtttat ggtttgaacc tgaaatggtg
     2281 aataaggata gtgagttata tcgcacacat ccgaattgga ttatttctac acctaatcga
     2341 aaacctaatc atggtaggaa ccaatatgta ttaaattttg ggttagatga ggttgttgaa
     2401 aatattttcg atcaaatgtg taaaatcatt gatgaatcaa acttagatta cattaagtgg
     2461 gatatgaatc gtccattgac tgatgtattt gacagtcact tgtcagcaga tcaacaagga
     2521 gaagtattcc acagatatgt actaggcgta tatcgcttat atgaaaaact tataacaaaa
     2581 tatcctaaca tactatttga gtcttgttca tcaggtggtg ggcgctttga tcctggaatg
     2641 cttcactatg cacctcaagc ttgggctagt gatgattcag atgcaattga aaggttaaaa
     2701 attcaatatg gaactagtat gctgtatcct ctttcgtcta ttggtgctca tgtatcaatt
     2761 gttccaaatc atcaaacaaa ccgtataaca cctataaaaa ctagaggaaa tgtagctttt
     2821 tttggtgcat ttggatatga gcttgactta aatgaattaa gtgaaggcga tttgaggatt
     2881 gtaaaagaac aaattgcctt ttataaaaaa tatagaacca taattcataa tggtactttt
     2941 tatagactat tatcaccatt cgatgatgat aatcaaaccg cgtggatggt tgttagtcat
     3001 gataagaaaa cggctattgt tgctcattat aaaacattaa atgaggtaaa tgctccttac
     3061 cgccgactga aattaaaagg gttagataat gacggacttt ataatgtagg acaaaatagt
     3121 ttgcgatctg gaatggaatt gatgagagca ggactagtct gttcagatgc atctagtgga
     3181 caaataaatg atcagaatcg acgcccagaa acatttgatt ttgattccaa gatttgggtt
     3241 ataacacagg aggaaaagta gagatgaata accaaaaaag cttacttcaa aaaggagcaa
     3301 tcttaagtat ttcactaatg ttaacaagct ctcaagcaat taatggtgtt attccacaaa
     3361 tgaaacagtc tttggggata tcacaaagtc aaagtgaact tttaggaact gcaccaagta
     3421 taactgttat tttgtttatc ttattatcta gttactttgc caaaagaata ggaatgaaaa
     3481 agacaataat tttaggttta ttattagctg gtataggagg aattattcca gtatttacag
     3541 ctaccttcca aaccgttctt attagtcgag taatattagg tgccggttta ggagtatata
     3601 attcattggc tgtgacatat atcagctctt tatactctgg caatactaga gcaacgctat
     3661 taggtattag aaattcaatg gaagctttag gtcagacaat ccttattttt cttgctggag
     3721 ttttagtgaa cattaattgg acggcttcgt ttttagtcta tgcaattgcg tttcctgtag
     3781 ctctcttatt cgcgctaaaa gttcctgaaa ttagagatga aaatagtgac atacctgaaa
     3841 atcatgtaaa agaaaagatg aatccaatgg tttttgccct agttctattt gcaatcttac
     3901 tcgtaatgaa tagtattgct atttctgtac gatttgcatc aattgcaact gaaattaaag
     3961 gggtaaactt taatgctagt aactatttag ctctaatgcc tatcttagga atactagcag
     4021 gatttatgtt tggaccaata aataagtgga taggaaaagg aaccctatac ttgggaatta
     4081 tattctttat aatttcaaat ttgttaattg ctgtgtcaaa cggtaatatg acgttcctgc
     4141 taacgggttt atttttatca agtataacag gatcatggtg cttcccattt atctttagta
     4201 acttagataa agtcactaca aagaatacaa ttaattttgc tacttcattg atttttattg
     4261 gctgtaatat tggtaatttt atagctccta ttgctatgca attagcacaa tttctaacaa
     4321 gaagtacaaa tttgactgct ccattttttg tattcgcagg aatatttatt gtgatcctat
     4381 ttgtaacatt ttttgcgaca aataaaaaaa atactaga
//
LOCUS       DAXLPY010000122         4372 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.125, whole genome shotgun sequence.
ACCESSION   DAXLPY010000122 DAXLPY010000000
VERSION     DAXLPY010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.125"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(83..1051)
                     /locus_tag="ACF3UF_002625"
     CDS             complement(83..1051)
                     /locus_tag="ACF3UF_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3672682.1"
                     /translation="MSKKRTIVNEWEKLTALSNRRLNVQTLVQTIKLNWSIDRITIVG
                     KLNQNIFYHTQHDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQHDENIAYIEISKW
                     QEGKGRIDFNPNKISRFLADSMKNFIHDLFLEPHFSRADVACDLIDVPDEFITQYRII
                     DPVSFKLIYGRSGKLETVYWGSRASERQIRLYNKKIEQEMKRKVVPSEINTWWRLEMQ
                     LRRGKATEWYAMVKESLDSFVSPHFLPTDIKPTDKVMIDGLLANHSNWAILSRNSKYK
                     YRNLLKRESQNDELTNHLRETFEESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1496..2902)
                     /locus_tag="ACF3UF_002626"
     CDS             complement(1496..2902)
                     /locus_tag="ACF3UF_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HFD3672683.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDRQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYIYRQREE
                     NERDKALMASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSENEIEW"
     gene            complement(3124..3486)
                     /locus_tag="ACF3UF_002627"
     CDS             complement(3124..3486)
                     /locus_tag="ACF3UF_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672684.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDDLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3490..3798)
                     /locus_tag="ACF3UF_002628"
     CDS             complement(3490..3798)
                     /locus_tag="ACF3UF_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672685.1"
                     /translation="MDKIDLREETVDRIELMYERLADYLNLPDEDNYSEMLERIMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQISVINSKEKEM
                     "
     gene            complement(3807..4226)
                     /locus_tag="ACF3UF_002629"
     CDS             complement(3807..4226)
                     /locus_tag="ACF3UF_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672686.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
BASE COUNT         1241 a          979 c          604 g         1548 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attcttcaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcgcttta ataaatttcg atatttatat ttcgagtttc
      241 ttgacaaaat cgcccaatta gaatgattag ctaacaatcc atcaatcata actttatccg
      301 taggttttat atcagttggt aaaaaatgtg gactcacaaa gctatccaaa ctttctttca
      361 ccatagcata ccattccgta gctttaccac gtcttaactg catttctaac cgccaccaag
      421 tattaatttc tgaaggcacc acctttcttt tcatttcttg ctctattttt ttattgtaca
      481 aacgaatttg ccgctcgctt gcccgactac cccaatacac cgtttccagt tttcctgagc
      541 gtccataaat taatttaaat gaaactggat caataattcg atattgcgtg ataaactcat
      601 caggcacatc aataagatcg caggcaacat ccgctcgtga aaaatggggc tctaaaaata
      661 aatcatgaat aaaatttttc atggaatccg ctaaaaatcg actgatttta ttaggattaa
      721 aatcaatccg cccttttcct tcttgccatt tagaaatttc aatataggca atattttcgt
      781 catgttggtc taatagctgc caaccattat ttccaaccgc ttttaaatag ccattgcctt
      841 catttacccg cataagctgt tcaaaatcta atattaatac atcatgttga gtatgataaa
      901 aaatattttg attcaacttt ccaacaatgg taattcggtc aatcgaccaa tttaatttta
      961 tagtttgtac caaagtttga acatttaacc gcctgttaga cagggctgtt aatttttccc
     1021 actcattcac gattgttctt tttttactca tattcagttc ctcctcaaag aaaaaagaga
     1081 tttttggaaa gaatttccag agttcacgta actctaaaaa ttcataacca tcaatctcta
     1141 gtcttgaaga aacctaaaaa tattcgtata atgaatttga gttacggaac tagtgtggtt
     1201 agtttccgta aaggtcgaga acgttggtag cgttgctcga cttatttttt tgctcttttt
     1261 ccagttcatt tgtttgctaa ctcaataata gcacttctct ttagctatgc aaataccaaa
     1321 aaaataaaac cgcacccttt gaaaagggcg cccccaaact tcgctaacgc taagttggcc
     1381 aaaaaatgga cttgccattt tttagcaaat gtcagcttca ggggctagtg gtttagccgt
     1441 caactcctta tcctcggcac aaaccgcctc cggtaccgtt gactgcacat cgtggctacc
     1501 actcaatctc attctcagaa cgctctaatt tatgctgtga gacgttttga cgataaaata
     1561 aggttttctc ctgctctaat acttctaatt cctcagaaag ccccatatcc ttttctgcaa
     1621 gaccaaaacg gatagacaaa cgagtgatcg atttttgaaa tgcgtttttt aatcgctcta
     1681 aacgctggcg taaagagcga ttttcttctt tcagcttttt attttccact tgtaaatctg
     1741 ctaattgttt tctaccagac aaatgacgct cttcttccaa tgtagctaca tactcattta
     1801 attctgtatt ttgctcaagc atctgtaaat attgctcact catgttatca gcatttctct
     1861 tggcatttgt tgctctcgta gctcgttgat acaaatcaac aaaatcattc ccagataaat
     1921 gatacgaacc atcaggaagc ctcttgaaac tttctaaagg aaccatatct ttttggaaaa
     1981 tgaccgccat ctcttttttt acattcagca tatttttctt ctcttcttca atcttcgctc
     2041 tctcagaagc catcagagcc ttatcacgct cgttttcttc tctttgccta taaatatacc
     2101 tcaactcatc agaaacgctc tcacgctctt ttacagccgt ttggcgcaat tcagaaattt
     2161 cactcatgat ttctttgtat tcgtgaatat ctttaatttt gttggtaccg acaatatccc
     2221 ttttccaacc gtaatcattc attaatcgtt ctatagagtc aacttcttga tttctaaaat
     2281 tattgaaaag cactcgacca ttatctttat cagcgtgtat cccttgttga accagtgctt
     2341 tattaaagct cggctgcttt tgaacacccc gtttataacc ttcagcaacc ggcacaatat
     2401 tcaagtgcag gtgcggactt atttcgtcat tatgaataac agcattataa acagccaaat
     2461 tagggtttct ctcttgaaac tccttgtaat actgaaccaa aattttattg gcaatcactc
     2521 gattttgttc agcttgttgt ttcgatatgc cagtagaaga accatctgct cgatttgtct
     2581 ggaaatcatc taaaatgcct atttgcacaa taaattctcg ttgaggttcc aactttttat
     2641 ccttgcgcac tttcgctaaa tagtcctcga tttttctatc ggctcttttt tgtttcgcat
     2701 tatatttttc taccacttcg ccaaacaatt cctcatattt atctgctaga ttcgtctgct
     2761 ctaaataaat attttcatcc gatttcgtga agtcaatgtg cttatgccaa tcattggttt
     2821 tctggcgatc agttaactca cgattattat gagaaatact tgtattcttc gttccttttt
     2881 taaatgaaat actaaacccc aagttaaaac cctccttcgc gctgtcgcta ataaaaagat
     2941 tgtaaacctt tctgttactc tttgtcaaag agtaacattt tcctaattgt gacatggatg
     3001 tcacaattcc aaacgctctc cgagggtttt cgctgtcaca agtgacaacg aaaaaaggag
     3061 ccgaaagcgt atcacgctat caactccttt tatgctttat tttgcttcac gcaaaataat
     3121 cgcttatcgt aaattcacgt cattaaatat tgacgtaaat ttactctcac tcatctgact
     3181 tttcttattc ggtatcactc cgaataagtc gtcagattca tcgggataat ctcgttcgct
     3241 tggcgctgat ttttcatcag caagccactc attatccact gttttttcgt gttgctgatc
     3301 gtcagaaatt gacgataacc accgctcaaa atcagcaaaa gtttcaaacc caaaacgctt
     3361 gcgaagagcc ttgcccattg cagcattttc tttctcaatc aagcgttttt tctgttggcg
     3421 aagtttcgct tgttcttttt ttaatttttc ttcttgcgct ttaatatctg ctaaagtcat
     3481 tcccataaac tacatctcct tttctttgga attaataacg gaaatttggt ttaactgcat
     3541 aacatgactc attaatttca accaaaattc tttttctgat tcatcagttg tttgcgctaa
     3601 atgcttatga acaaattcat tagtcaaaac tgaagatttt gctagatcag cattgataac
     3661 cgagttgaga acatccataa ttcgttcaag catttcacta taattatctt catccggcaa
     3721 attcaaataa tcagctaacc gttcatacat caattcaatt ctatcgactg tttcttctct
     3781 caaatcaatt ttatccatgt cacacctcac ttccagaatt gccaccattt tcgatttttt
     3841 aattcttgat tttctagtaa caactgatcg tttttttgtt gctgaagcaa agtcaatttt
     3901 tgttggtcac gaatcatttc cgttaattca gaaatatgcc tatctttttc cgctaattgt
     3961 tcacgcaaaa attcattttc tttttctaac gggaaatcat tgcctgcatc attgaccggt
     4021 aaatcaccag tcaattgacc accttttgac cgataaattg accgcacaac accaatcaat
     4081 tccttgtcta acatgataac cccattatct ttataccgag caaggtcata acctgcattg
     4141 accagttgat tgcgcactgt atttttagat atacccaact catcagcaag gttttttatg
     4201 gtcatttttt ctggcaaatc agtcattatc ttctccgtta ctttcagcta ccccataaac
     4261 atatttaaca gcatgcttag ggataatgat tggggaatca attttattat ttttcaaaat
     4321 caactcatac tgcgttacat caagtaactt accggacatt tttttgctat cc
//
LOCUS       DAXLPY010000123         4326 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.126, whole genome shotgun sequence.
ACCESSION   DAXLPY010000123 DAXLPY010000000
VERSION     DAXLPY010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.126"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(81..1301)
                     /locus_tag="ACF3UF_002630"
     CDS             complement(81..1301)
                     /locus_tag="ACF3UF_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFD3672687.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1321..1932)
                     /locus_tag="ACF3UF_002631"
     CDS             complement(1321..1932)
                     /locus_tag="ACF3UF_002631"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFD3672688.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1975..2907)
                     /locus_tag="ACF3UF_002632"
     CDS             complement(1975..2907)
                     /locus_tag="ACF3UF_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFD3672689.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3328..4188)
                     /locus_tag="ACF3UF_002633"
     CDS             complement(3328..4188)
                     /locus_tag="ACF3UF_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3672690.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1234 a          869 c          710 g         1513 t
ORIGIN      
        1 tattattggg aatcccagct taaatcatag ataccgtaag ggactttatt ctttatttaa
       61 aactttgcaa cagaaccttt ttattttaca gaagcactcg aaactgcatc tactgcagtt
      121 tcatcgtgtg tgctggcgct ggttactgca tctgtttttc caccatgaac agatgcactt
      181 gaaaccgcat cttcatttcc aacaagttgt tgacccgttt gttgtaaata ccactcaatg
      241 attggtttga aatcaagaat gtattcattg attccagcat actctccatt ttcatcatgc
      301 attgcttggt aattatgcac aatatatttt tctggcactt gttttggtac atgaacacgt
      361 accgcatctg ttgctccgct tcgcagttgt tgaattaccc actctacatt tttatacgat
      421 ttttctgggt gacagttggc taatggattc cctacctgac cgggcacacg agcagctaac
      481 atctctttcg cttcttggcg caaattataa tataaaaatt ggttattatt atctgcaaaa
      541 gttaattcca tcggcatcga atctaaaaag taattgattt gatccactgt caataaccca
      601 cgatttaatt tgacgtaagt atttccagaa acggcaccga ctgcttcaga agctttttcc
      661 aaccaatgat catctgacat atcaacatcg ggtattgtcg tagcaattgt tcctgtcgca
      721 tgcaaatctt ctggtggaag ctttttaggc cctgctaagg tagacacgac tttaatgaat
      781 tttacaaaac ttgctaatgt actgcctaaa aagtcaacag ttcgtggatc aatcaagcga
      841 tcttcttggt caaatgcttc ttttgctttt cccaataaaa attcatttcc gggcatcact
      901 aatgcattca cgcctggtgc gtccaaaatt tggcgcaagt gtaattgcgc gcgtgaagtt
      961 ccttgatcgt agtaagaagc acccacaacc attacaggtt tattttcaag tggatggatt
     1021 ttaaatgata gccattcaag tgcacttttc aatcctgctg gaaccgtatg attgtgttct
     1081 ggcgtagcaa taattacccc atcagccatt aagattttgc gatttagctg ttgaatagca
     1141 ggactatttg tttgatcatc atcttgattg aacagaggta aatctttgat ttcaatgatt
     1201 tctaaattaa atagttcatg atattgtttt tggataaatg ttaataattt acggttatat
     1261 gaaagttcag ctgctgatcc gacgatacct attaatttca tctttgtttg ctcccctcga
     1321 ttaaatcgtt tcccatgaaa agctttcggc ttcacgttta tttgcttggt gcgcatgttg
     1381 caattgacta gtgattgtga caaagagtaa gaaatctttg aatagttcac gtaattttgc
     1441 gacttgttct tcatcaatga gtcgtccttg ctcatcaaag gcttggagtg aatgacccaa
     1501 taaaaattct gagcttggca taattcgtgc ctttaactct ggtgaatcca atatttggcg
     1561 caaatgtgct tgtgcgcgtg aagaacctaa cgtgccataa gacgctccgg taatcatcac
     1621 tggtttatcc acaaacggaa aaataccata tgaaagccaa tttaatgcgt taatcaatga
     1681 agcaggaacc gcatggtcat actctggtgt gctgatgatt acgccatctg cttgttcaat
     1741 ttttccagca atttctttaa caacatttgg tagttctgtg ttttcaggtt tgttaaatag
     1801 tggcagctcc ttgatttcga caatttcgat ttctgcctca tttacaaaat aatttttcat
     1861 aaactgtaat aattcacggt ttgttgaccg cgttgaattt gttcctacta atccaataaa
     1921 tttcatcttc attctctttc ctttctaaca tcgatttctg actgttcgca cgtactaaat
     1981 tttttcaaat ccttttgtat acaagaattg attctctttt gttacaactg ctccctcgat
     2041 acccggctgt tcttcaagcg ctttcaacac ttctaaagaa gatgctccaa ataaacgtgt
     2101 agtccagatt tctccatcta cagaagaatc agacaaaatc gtcaggcttg ctacgtcatt
     2161 tttaactgga aagccagttt tcggatcaat gatgtgatga tacactgacg aaccattttg
     2221 tagataacgt tcgtagattc cagaggtaac taaagattgg ttgtttagtt taaccaccgc
     2281 aagcgactct tcacgtgaac ctttaggatt tcgcaaacca atacgccaag caccatccga
     2341 acgtcttggt gattcaccaa aaacaacgat atttcctcct aagttaacta aagcaaacgc
     2401 tgcatttcgc tctcggcaat gtgtaattaa tttatctgca atgtaacctt ttgctaacgc
     2461 ccccaagtca atcatcattc ctggtttggt taaaaaaacg gttttcattt tttcatctaa
     2521 ttgaatttgg tgtggatccg ttagcagaag taactcagtt atctctgctt ttgttggaac
     2581 caatgcatct tcaaatccaa tgtgccattt ttgtacaacc ggaccaatag caatattcag
     2641 ataactattt cttgcacaac tatgtgcttt tcctaatttg atgagctcaa aaagttcagg
     2701 atgtacaatc acagcttgtc gtccagcagc ttgattgatg gccattaatt cagaagttgc
     2761 atcatgtgcg ctgaagcgat gttcataaac gtgcaaccat tcgcctaact ctgctagtaa
     2821 tcgactaggc tcttcatgcc caacttgtaa tgtaattgtt gtccccatca tttgccagat
     2881 tttcgtttct tcgatcacct gattcatttt gtaccttctt tacttgaact acggattaca
     2941 tgagtaatta gtttttattt ttgttactgt tttcacaacc agatgatacg cctgctagat
     3001 ttatttgtca accgatttta tatatttttt tatataataa ggtaatttta atataaaatt
     3061 ttatattgta aaaaaacaaa taagggaaac aaacaacaca tttttgtgtg ttgcttattt
     3121 ccctctaact atcgttttct atttgatggt taacctactt aaaataaata ctgcaacgac
     3181 aaacggagat caagcatgct ttgtaacgta ttttacgata attacgactt tattttatta
     3241 ctctatcttg ctgccatacc cgtctatccc taatcatctt tggtgaattt tttcaaagtt
     3301 agcataacaa aaataagtat tttttcctta gttaatcaat agtatcattt ttttcatatg
     3361 atttaattca tcaattaatt ttttgttttt attaatttta gcaaaagcta gtgcatcttg
     3421 aatcaattcg agcacttctg ccttcgactt atttttagcc tgtgcgttct tcgctaattg
     3481 ggcagcagct cgtgctaagt aataagtcaa atggttatcc gaacaaatat cgattgcgta
     3541 atttagtagt gcatcacttg tttccaaatc accgtcttgc gcaaaaaaaa caccacaatg
     3601 aaagacgata tttaacaccc gccagatatc ttctgttgta cgaatcggat acgtataaat
     3661 tttttcaaac actcgattga aataaacttc tgctttttcc aactcttttt ctctagcata
     3721 gaccattcca atacctgtat atgccaataa acgaaacaac gtgttggctg tttctgccat
     3781 caacaactga tcaaaatgga acaacacatc cgtaattggt gcattcgtaa aaatcatttc
     3841 aaatcctttt agatagtagt aacgtgcaat cagctcagac tcgtcaatta ccttgggatc
     3901 aatggctgct aaaatctgtg tcaattgttc atattcactc gtaatcagtg aaaactctgc
     3961 tttttctagc tgttcatcaa gttgtgtatt gatcacgttc atcgaagaaa aaagttcaac
     4021 taacggaaga ttgattcgat tacataattt gattaaaatt tttaacgaag ggacttgacc
     4081 attgttctca aatttactta atgttgcttg tgtacaaatt ccttcagaca cttctttttg
     4141 agataagttg gcagcctttc ttgccgtaat aaatttttca atgttcatta ttttctctcc
     4201 aatcagacct cacacgaaaa tcatttctgt ctcgatttta gcatgttttc tttgggaatg
     4261 ctttaggttc tgttgcaaag ttttaaataa agaataaagt cccttacggt atctatgatt
     4321 taagct
//
LOCUS       DAXLPY010000124         4318 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.127, whole genome shotgun sequence.
ACCESSION   DAXLPY010000124 DAXLPY010000000
VERSION     DAXLPY010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.127"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            287..694
                     /locus_tag="ACF3UF_002634"
     CDS             287..694
                     /locus_tag="ACF3UF_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672691.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="ACF3UF_002635"
     CDS             708..1109
                     /locus_tag="ACF3UF_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672692.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1111..1482
                     /locus_tag="ACF3UF_002636"
     CDS             1111..1482
                     /locus_tag="ACF3UF_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672693.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1518..1820)
                     /locus_tag="ACF3UF_002637"
     CDS             complement(1518..1820)
                     /locus_tag="ACF3UF_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFD3672694.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2078..2191)
                     /locus_tag="ACF3UF_002638"
                     /pseudo
     CDS             complement(2078..2191)
                     /locus_tag="ACF3UF_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(2574..3807)
                     /locus_tag="ACF3UF_002639"
                     /pseudo
     CDS             complement(2574..3807)
                     /locus_tag="ACF3UF_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
     gene            4064..>4318
                     /locus_tag="ACF3UF_002640"
     CDS             4064..>4318
                     /locus_tag="ACF3UF_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3672695.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAF"
BASE COUNT         1447 a          715 c          767 g         1389 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa atgtttgact ttaatgaata tttatctatt
     1141 tccaaacaaa ttgaatcaga tgataaatat aattctaaag aatcttatag aagaactgct
     1201 gtttcaagag catactacag tgcttttaaa aaatctgatg agtatttgaa agaaaattat
     1261 gatattattt ataatggaag tagcggaaaa ggaagccacc aaaccgtttg gaatttgttt
     1321 tcaacagtta aggaattgaa taccttagga atacataata gtgggtatag aatgttagag
     1381 aaaagaaaat gtgctgacta tattcctaat gaaaccatta cgaaaacaga tatggcgctg
     1441 atgaatcgag aagcagaaaa aataataaac aaactcacct aatgaatttc aagcgagttt
     1501 gtttgttatt tttttattta atctttgtat ctttctggat caacgaaagt atactttata
     1561 tagtcataac gccgatgatc gctacgtgcg tccggcacgt cagtcacgat atcaaacaaa
     1621 aagtatacac ccttcttcat tctagttttc gcagcaggaa ttttgaaata gttcttatta
     1681 gaatagtaga gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaattc
     1741 catactttat aaaaatcttt gataaatcta ttcgaagggt caaatttaaa ccataattgt
     1801 gtttttcctt ccatcagcat aaaagttcac ctcaaaaaga gtatacgaac gaatgttctt
     1861 tttgtgaagg cggaatttaa tatactgaat aatagaaaac aagtacttgt gccaaattat
     1921 gtgccaaaaa aattcgaatt caacaaaatg taaacaaata gaaaaccttc tatattaaga
     1981 tttcctgcaa taacaaacac aacagaagac gtgtaatagt tagtcaggaa cgtacaaata
     2041 acccctgtat cctttgcggt acagggggtt attttgtata agtagacatt gtagtttcta
     2101 aactgctatg tcctaaacgt ttcgatacgc taagtatatt tactccttga taaagtaaaa
     2161 tagatgcatg cgtatgtctt agtccctcaa taaacagtcg aagagaaaat aggcaaaaat
     2221 tgattactaa agaaaaactt actaggtcga cggtgtagtt gattttcata cttcaacaga
     2281 ttcgaattaa acgatttcga ttggcttata ccagtcctat ccgacgaaag atatatcgtt
     2341 cttaactcta gcggtataac ttgaagcttt acgtaaagcc aatgggaatg aactggagat
     2401 gactttttat tatttttagt aatagctgat gggttaatac ttacaacttt ccttttcaaa
     2461 gtaccatata aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt
     2521 agatccttta ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc
     2581 caatcgccat ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc
     2641 atcttgtcag atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct
     2701 gctaattctt catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct
     2761 agtgctaagt gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat
     2821 tgagaaatag gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca
     2881 tctgtatcaa gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaatgact
     2941 tttccatctt taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc
     3001 tttgtacttg aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc
     3061 gtcggcatat ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa
     3121 agatggtttt taggcaatcc gataatgata tctgtaccgg gagcagtata gtgcagggca
     3181 gaaaattgtt ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc
     3241 catgctaaga cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat
     3301 gcctcaactt gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca
     3361 gccgcagcca cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt
     3421 agtgctttgc cagccgctga ttgataagac ggctactcga tggctatcta caccagcaaa
     3481 tgcatcggga tcggcagaaa caacactgat cctgcttgct cctttttcaa gccattcatc
     3541 cgcttgatcg attttagatt gtggtacatt ctcaatacga tccgttgcag catgtaaaag
     3601 aaattctctt tggatctggt cgtcagtcca ttgaacgata acctcagcgg ctcctagttt
     3661 ataagcttct tgtgtgatca atcgagcaag gggtgcctgt tccacgctga tctgtaaaac
     3721 aactgtgtgt cctttttctg tggctacgcc agtttctgca attaagcgtg catatttttt
     3781 tagaagttca ttaaaatcag ataacataat aaaaattcct cctcaccatt ttttctggta
     3841 actattagca tgataccatt taattatgat tcaaacaatg aggcctttaa ataaaaaaaa
     3901 gaggttattt ttttaaggtt aagtttcatg atatatgtta ctacttgcta tttcagcttg
     3961 tgaagaaaat caaaaactaa ttttgcatat caaaaaaaac atgttacaat gaaattaatc
     4021 aatggtggaa gcgttataaa aaaattaagg agattaaaaa aatatggcaa gaaaaaagac
     4081 gattactaga gaacagattt tggcagctgc ttatgaagta gctgccaccg atggatttac
     4141 acgatttact gcgagaaaca tcgcgaacaa aatgaattgt tccacgcaac cgatttatct
     4201 tgagtttaaa aatatggatg acttgagaca agctcttttt gagcagatct atgatcattt
     4261 acaatatgaa gtgttcactg ttgagcatac agggaatacg attatcgatc ttgctttt
//
LOCUS       DAXLPY010000125         4257 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.128, whole genome shotgun sequence.
ACCESSION   DAXLPY010000125 DAXLPY010000000
VERSION     DAXLPY010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.128"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            148..333
                     /locus_tag="ACF3UF_002641"
     CDS             148..333
                     /locus_tag="ACF3UF_002641"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672696.1"
                     /translation="MSTLQEKQLQFNPHLLRNEEIFRGASIYKIITIDMMKQIKARDK
                     QIELAENIVDYLLHTNF"
     gene            complement(417..3383)
                     /locus_tag="ACF3UF_002642"
     CDS             complement(417..3383)
                     /locus_tag="ACF3UF_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFD3672697.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            3529..4104
                     /locus_tag="ACF3UF_002643"
     CDS             3529..4104
                     /locus_tag="ACF3UF_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672698.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
BASE COUNT         1311 a          787 c          740 g         1419 t
ORIGIN      
        1 tgtcagaaca ggcatttatc ccgctttgat aaggtttatc actctattcc ttcttcaccc
       61 gttgggtgaa gaaaaaaata tacaaaaaga gcacactcta tgttattgta aagtcgatca
      121 aaacaacaaa aacaagaggt gtgctcaatg tcaactttac aagaaaagca actacaattc
      181 aatccccatt tgttgagaaa tgaagaaata tttcgtggag caagtatcta taaaatcatt
      241 acgattgata tgatgaaaca aataaaagct agagacaagc aaattgaatt agcagaaaac
      301 attgttgact acttattaca tactaatttc taagaatata aaggggtagc gtcaggaaaa
      361 tgcggattta caacgctaag cctattttcc tgacgaatcc ctcgttttta acaacgttaa
      421 gaaagtttta gtggtcttaa agaatttaat gagactactt tctctgagtt aaaatggtat
      481 tctcctagta aattaatatg ttcccaacct aagggcgaca tatggtgtaa caaatcttca
      541 ttaaagctac ctgtccgttt tttatattca actgctgttg ttaggtggag agtattccaa
      601 atacttatag cattgataat tatgtttaaa gcactggctc tttgcaattg atgctgtatg
      661 gtgcgttctc taagctcacc ttgttttccg aagaaaatag ctcttgccaa tccattcatg
      721 gcttctcctt tattcaatcc tctttgtatt tttcttctta atgattcatc cgatatataa
      781 ttcaaaataa agatcgtttt ttctattcgg cccatctcac gtaaggctgt agctaagctg
      841 ttttgtcttg aataggaacc tagcttcccc ataataaggg atgctgaaac tgttccctcc
      901 cttatagaat gagctaatcg caaaacatcc tcataatttt ctttaatgac ctttgtattt
      961 atttgtccac gtaaaatggc ttctagtttt ggatactcac ttgctttatc tatcgtaaat
     1021 aattttgagt ccgataaatc ccttattctt ggggcaaatt taaatcctaa taaatgagtc
     1081 agtccgaata tttggtcagt gtaaccggca gtgtctgtat aatgttcctc tatgtttaga
     1141 tccgtctcat gatgtaacaa accatccaaa acatgaatcg catctcttga attagtatga
     1201 ataatctttg tgtagtaaga agagaattga tcacttgtaa atcggtagat ggtggctcct
     1261 tttccagttc cataatgtgg atttgcatct gcatgtagtg atgaaacacc tagctgcatt
     1321 ctcataccat ctgacgaaga tgttgtaccg tcgccccaat agaaaggcaa ttgtaattta
     1381 tgatgaaagt ttactaatat ggcttgggct ttattcatgg catcttcata catgcgccat
     1441 tgagatacat tggctagttg cttatatgta agtccgggtg tggcttcggc catcttgctc
     1501 aagccaatat tcattcccat tcctaaaagg gcagccatga taatgattgt ttcttcctta
     1561 tctggttttc gattattgga agcatgagtg aattgctcat gaaatcctgt tatatgggcc
     1621 acatccatga gtaaatcagt taattttatt cttggtagca tctgataaag gcttgcacta
     1681 aatttttttg cttcttctgg aacatctttt tctaagcgtg caagtgatag ctttcctttt
     1741 tcaagagaaa ccccatctaa cttattggaa ttggcagcta accactttaa cctttcatta
     1801 aagctgctgg ttctctccgt tatataatct tcgaatgata aactaactga taatctcgta
     1861 ttccccttcg attgattcca tgtatcttcc gaaaacaaat attcctcaaa atccctatat
     1921 tgtctgctgc caacaatgga aacatctcct gcccgaacat gctcccgaag ttctgttaaa
     1981 acagccattt catagtaatg acgattaatt gttgtaccat catcctcgta taaatgtctt
     2041 ttccatcgtt ttgaaataaa atccacaggt gagtcatcag gcacttttcg ctttccagat
     2101 tcgttcattc ctcggataat ctcaacagct tgtaaaagtg gctcatttgc ctttgtagaa
     2161 tgaaattcca atactcttaa tagcgttggc gtatattttc ttagtgaata aaaccgtttt
     2221 tgcagtaagt ctaaataatc atagtcggca ggacgtgcaa gttcctgagc ctcttctact
     2281 gaagagacaa aggtattcca ttcaataacc gattctaaaa ccttaaaaac gtctaatttt
     2341 tcctctcttg ctttaattaa tgcttgtccg atgttcgtaa agtgtataac tttctcattt
     2401 agctttttac cgttttgttt ctggatttcc tcttgagcct tacgaccttt tgataacaaa
     2461 ctaagtattt gcctatcatg aatttcaaac gctttatccg ttagctcctg agtaagttgt
     2521 aataaataga tggttaatat cgaataacgt ttattttctt gaaagtcacg gaatgcatac
     2581 ggctcgtatc ttgagcctaa gcgagacagc tgcaacaggc ggttacggtg caaatgacta
     2641 atttgcactg tttctaaatc cattcctcgt atgtattcga gtcgttctat tatttttaga
     2701 aaagtttcgg gtgaaggatg acccggtggc tcttttaacc aacccaatat cgttttattg
     2761 gattcggatg gatgctgcga ggtaataatc ccttcaagct tttctttttg ctcatttgtt
     2821 agagatttac taaccgtatt aaatagcttc ttttcagcca ttgcccttgc ttcccacacc
     2881 attctttcaa gtgtagtgat agcaggcagt ataattttgt tttttcttag aaaatctatg
     2941 cattcatgca gtagatgaat ggcatcacca ttttccaaag ctaattgatg aaggtactta
     3001 aatgtcattc gatattcact cagggtaaaa gttacaaagt cgtattcact tcgaatttct
     3061 ttcaaatgat cccaaagtgt attttccctt tgaggataat gatcaagcga ggatggacta
     3121 acaccaatct gtttcgatat atattgtatg accgaatctg ggatgctttt gatatgagtg
     3181 tatggccaac cgggataccg aagaacagct aattgaacag caaatcctaa acggttttct
     3241 tccctccttc gcttattaac tatttctaaa tcccgtttgg aaaaagtgaa gtaggtcccc
     3301 agtatccatt catcttcagg gatttgcata aaagcctgtc tctgttccgg tgtaagcaat
     3361 tctctacctc tcgcaatttt cattcagtat cattccattt ctgtattttc aatttattag
     3421 ttcaattata tatcaataga gtgtactcta ttgatacaaa tgtagtagac tgataaaatc
     3481 atagttaaga gcgtctcata agacttgtct caaaaatgag gtgatatttt gcggaaaatc
     3541 ggttatattc gtgtcagttc gactaaccag aatccttcaa gacaatttca gcagttgaac
     3601 gagatcggaa tggatattat atatgaagag aaagtttcag gagcaacaaa ggatcgcgag
     3661 caacttcaaa aagtgttaga cgatttacag gaagatgaca tcatttatgt tacagactta
     3721 actcgaatca ctcgtagtac acaagatcta tttgaattaa tcgataacat acgagataaa
     3781 aaggcaagtt taaaatcact aaaagataca tggcttgatt tatcagaaga taatccatac
     3841 agccaattct taattactgt aatggctggt gttaaccaat tagagcgaga tcttattcgg
     3901 atgagacaac gtgaagggat tgaattggct aagaaagaag gaaagtttaa aggtcgatta
     3961 aagaagtatc ataaaaatca cgcaggaatg aattatgcgg taaagctata taaagaagga
     4021 aatatgactg taaatcaaat ttgtgaaatt actaatgtat ctagggcttc attatacagg
     4081 aaattatcag aagtgaataa ttagccattc tgtattccgc taatgggcaa tatttttaaa
     4141 gaagaaaagg aaactataaa atattaacag cctcctagcg atgccgaaaa gccctttgat
     4201 aaaaaaagaa tcatcatctt aagaaattct tagtcattta ttatgtaaat gcttata
//
LOCUS       DAXLPY010000126         4157 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.129, whole genome shotgun sequence.
ACCESSION   DAXLPY010000126 DAXLPY010000000
VERSION     DAXLPY010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.129"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            179..775
                     /locus_tag="ACF3UF_002644"
     CDS             179..775
                     /locus_tag="ACF3UF_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFD3672699.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="ACF3UF_002645"
     CDS             899..2698
                     /locus_tag="ACF3UF_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFD3672700.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="ACF3UF_002646"
     CDS             complement(2976..3188)
                     /locus_tag="ACF3UF_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672701.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="ACF3UF_002647"
     CDS             3650..3799
                     /locus_tag="ACF3UF_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672702.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="ACF3UF_002648"
     CDS             complement(4052..>4157)
                     /locus_tag="ACF3UF_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3672703.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1228 a          707 c          729 g         1493 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DAXLPY010000127         3928 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.130, whole genome shotgun sequence.
ACCESSION   DAXLPY010000127 DAXLPY010000000
VERSION     DAXLPY010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.130"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..787
                     /locus_tag="ACF3UF_002649"
     CDS             <1..787
                     /locus_tag="ACF3UF_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFD3672704.1"
                     /translation="FFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESIS
                     ELRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKE
                     YKATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETI
                     DLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKH
                     EHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            798..2907
                     /gene="topB"
                     /locus_tag="ACF3UF_002650"
                     /pseudo
     CDS             798..2907
                     /gene="topB"
                     /locus_tag="ACF3UF_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            2923..3072
                     /locus_tag="ACF3UF_002651"
     CDS             2923..3072
                     /locus_tag="ACF3UF_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672705.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            3153..3749
                     /locus_tag="ACF3UF_002652"
     CDS             3153..3749
                     /locus_tag="ACF3UF_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFD3672706.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            3762..>3928
                     /locus_tag="ACF3UF_002653"
     CDS             3762..>3928
                     /locus_tag="ACF3UF_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFD3672707.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGS"
BASE COUNT         1434 a          682 c          849 g          963 t
ORIGIN      
        1 attctttgaa agtagtattg atctgttaag ttacgctgca ttgaatcggg agaaactaca
       61 agatgcctgg ttagtttcga tggacgggtt aaaacatcat gtaatcagtc attacgttga
      121 agagtcgatt tctgaattaa gacgaaaaca aacatttcct caatcgattg aaatatgtgt
      181 ggacaatgat cgtgcaggac atatttttta tgaaaaagaa cagatgaagg gaatcgttga
      241 tccttttacc aataagaaaa tccgttgtga gcgaggaatt ccaaatgatt ggcaagtacc
      301 taaagaatac aaagctactt atgaagcagt cgcaaaagaa atgagtgttg aacctgaagc
      361 aattatggcc atacacaaaa ctgaaactaa tttacagctg acaaatcaat tggtgtctgc
      421 tcatgatgtt caatctacgt ttggaaagat gttggcgaag ggcgaaccag tagaaacaat
      481 tgatttgaaa gaagcatgta ccacggtcgc gaaggaactg aaagtatgtg aacgcgcaga
      541 tggaacatac aactttgatc gtttttatag tagaaaagcc aacataaaag acgttaatgc
      601 aggaatcctt ctttcctata aagcagaaca atactacaaa ggctataaaa agcatgaaca
      661 tgaatttgta cctgaagtga aaaaggattg gaatgatcaa ttgaagcatg agatccagca
      721 acaagaaatc agaaagcaaa aacgtgcgat gttgtttcaa caaggcagac aacaagaaag
      781 ggagtgaagt cgtcactatg aaaaccgtca ttttagcaga aaaaccgtca caagcgaagg
      841 cttatgccga tagcttttct aaagctaccc gaaaagatgg gtattttgag atccaagatc
      901 gattgtttac aggagaaact gtgatcacgt atggttttgg tcatttagtc gagttagatt
      961 cgcccgatat gtacgatgaa aaatggaaac aatgggcatt agaacatttg cctattttcc
     1021 ccaatcaata ccactatcat gttcctaaag ataagaaaaa gcagtttagt gtcgtcaaac
     1081 gacagctgca gtcagctgat acgattgtga tcgcgactga tagcgatcgt gaaggggagc
     1141 tgattgcctg gtcaatcatt caacaagcag gcgccaatca aggaaaaacc tttaaaagac
     1201 tttggatcaa ctccttagaa aaagaagcca tttatcaggg attccaacag ttacgagacg
     1261 cagaagagac ctatccaaaa tttgaagaag tacaagcacg tcagatcgcc gattggttaa
     1321 ttgggatgaa cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa
     1381 gtttttcttt aggtagagtc caaaccccaa cactctatat gatttatcaa ttgcaggaaa
     1441 agattagaaa cttccaaaaa gaaccatatt ttgaaggaaa agcccaagta atcgctcaaa
     1501 atggcgcatt tgatgcgaag cttgatccaa atgaaaccca agcgacacaa gaagcatttg
     1561 aagcctattt aaaagaaaaa ggtgttcaat taggaaaaca gccaggtacg atccttcaag
     1621 tcgaaacaga gaaaaaaagt gcggctagcc cacgtctttt ttctttatcg agccttcagt
     1681 ctaaaatgaa tcaactcatg aaagctagtg ccaaagatac tttggaagcc atgcaagggt
     1741 tgtatgaagg aaaatatcta agctatccgc gaacggatac cccttatatt acggaagggg
     1801 aatatgcgta tctgttggat cacttagacg aatacaagca ttttttaaaa gccgaagcga
     1861 ttccgactcc tattcataca ccgaatagtc ggtatgtgaa taataagaaa gtccaggaac
     1921 attacgcgat cattcctaca aaaacggtta tgacagcagc ggcttttgaa caactaagtc
     1981 cactgcagca ggctatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa
     2041 agtataccta tgaagaaaca acgatcttga cgcaagttca gcagcttcag ttaaaggcaa
     2101 tcgaaaaggt gccgctagat ctaggttgga agaagttatt tggaaaagag agcgacggaa
     2161 aagagaagga agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtgg
     2221 atctacaagt tcttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga
     2281 tcactgcaat gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga
     2341 aagaagtgga aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac
     2401 aaaaggaata tatcaaggta gagaaaaata agctcgtggt gacgaataaa gggattttgc
     2461 tttgccaagc cgtggaaaaa gagccgctgc ttacgagcgc cgaaatgacc gccaaatggg
     2521 aaagctactt gttaaagatc ggtgaacgaa aaggaacaca aaccactttt ctagccaata
     2581 tccaaaaatt tgtctctcac ttattggaag tcgtaccagg gcaaatccaa tccactgatt
     2641 ttggatcgac gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt
     2701 taggaatttg tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt
     2761 gtacgtctga agcctgtgat tttaaaaggt cagaagggtt catttgaagc aacgattgtt
     2821 ttaaaagaag acttcactac aggctttgaa ttttctgaaa agaaaaaaac gaacttcaag
     2881 aaaagaacac gccgcactgc aaaataatgg agggttaatc ttatgcgtaa taccacacac
     2941 aaacaacaag aaatcgaaaa tcaaaaagcc aaaattcgtt cagaacagga aaaaatgcgt
     3001 gccagcaaac gaagactgca gcaattgaag aaccagcaga ggattcaaaa agaaatcgaa
     3061 ttagatcgat aaaatcttcc taactattgt atacgtataa acttatgtta tactgttttt
     3121 ataagtttat acgtatacaa aggagggaga aaatgacaaa agcaatggta tacaagctgc
     3181 tagaagaatt taatggaact ttggctttga aggatgccaa aaaagcgggc atttctcctg
     3241 taacgatcaa acgtatggta gatcgagggg agctggatcg agagtatcca ggttttttca
     3301 ccttacctgg tcaatttcct gatgaattgt ttatggcgca aaaaaaatat gaacgcggca
     3361 ttatttcaca tattaccgcg ttagatttgt atgatttaac agatatgatc cctagacaga
     3421 tcgatctgac tgtaccttac ggttatcacg tttctgaaaa aggattgaag gaattcgcag
     3481 ttgagctaca ctatacaaaa gcggaatggt atgaattagg taagattgaa ataaaaagtc
     3541 gctatgggaa tcctattata gcttatgatc cagaaagaac tttatgtgac atttggaatc
     3601 cctggtatac cgttgaggat gaaatcaaag taaaagcaat caaaaactat atggagtcgg
     3661 acagaaaaaa tcttagaaaa ttgaatgagt atcgacgaat tttaccaaca gacaaaacga
     3721 tgcgttctta tattatggct ttaaattaaa ggagaagata catgacacct acgcagttaa
     3781 aagcaaaagt gaagaatatt tctagagaaa aagaagttga tccgcagctt gttttaagac
     3841 attttatgat ggaaaaattc ttggaaaaaa tctcagagtc tccttatcgt gaaaattttg
     3901 tgttaaaagg cggcttcttg attggctc
//
LOCUS       DAXLPY010000128         3926 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.131, whole genome shotgun sequence.
ACCESSION   DAXLPY010000128 DAXLPY010000000
VERSION     DAXLPY010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.131"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(112..387)
                     /gene="prgO"
                     /locus_tag="ACF3UF_002654"
     CDS             complement(112..387)
                     /gene="prgO"
                     /locus_tag="ACF3UF_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HFD3672708.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(359..1312)
                     /locus_tag="ACF3UF_002655"
     CDS             complement(359..1312)
                     /locus_tag="ACF3UF_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3672709.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1924..3417
                     /locus_tag="ACF3UF_002656"
     CDS             1924..3417
                     /locus_tag="ACF3UF_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFD3672710.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3552..3848
                     /locus_tag="ACF3UF_002657"
     CDS             3552..3848
                     /locus_tag="ACF3UF_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFD3672711.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
BASE COUNT         1307 a          646 c          703 g         1270 t
ORIGIN      
        1 tgttgtatac ccccaaacaa tacacatatt ttgaaggatt aggattaata aagctaaaaa
       61 tatagtaagt atactaaata tatttactat atctagtata cttactatat tttaatcttt
      121 tgatcgtcta ttatatataa tccgttcctc gtcgtttaaa gtatcaacat aggcgtccat
      181 tgcaagtttg actatttcat acataggaat atcttttgca taactaagat cccgaatggt
      241 ttttagtacg ggaggatcta cttgaactgg ttttctttct ttcgcagtgt actttcgttc
      301 ccctaactcg acattaatat catctttaat tgaaatatct tcagcaccaa ttttcttctt
      361 atctttgttc gttggtaata atgccattta gtttaatctc ctttccaaga ggtaggatat
      421 gattggccat tgagtcagca tatttaggtg tataatcaaa tccttcaata tcaccatgtt
      481 gttcatagta ttcaattctt tcttctaatt ctgtaaagat gtctgcaaaa atagcccacc
      541 atcttcgatc tacataatca tttaattgga taccattctc accatacatt tctaaccgat
      601 ccgagccttt aacaatgctt ttaaaaatgt ttgattcacc atacttatca attgtttttt
      661 gatagtttgc gtgttgagag gaacgtcgca ctgagaaaag aacaggcaaa attccaatga
      721 tttgaagatg agactcttca aaattcgtga caatcggaac taaaacttta ttaataaaat
      781 cttctgttcc ttccattgcg taccgtttta attcttgcat tgcaataata taatctgcag
      841 cagttaagaa tgcacgaacc acattatctg ttgatggtgg gcagtcgata aagatataat
      901 cgaaattttt tctcaattct tctaaaggtt taatgaaggc caatgatctc ttacgacgat
      961 caggatattt ttcggacaag tattcattaa gttcttcaga tccaggagag ccagccataa
     1021 tatataaatg tggacttact tgagtaatac ctgaaaccca gtcccctttt ttgattgctg
     1081 cagacatgga tcgatcaaag ctagtaattt gatacgttga tccaatgttg gaagtagtat
     1141 ttctttgttg gtcataatca attagcaaca cgtctttttc aaaaagttga ctagaaacaa
     1201 tcgctaataa atcattgtct gtagtcttac caatgccgcc ttttctacct gtaagcatta
     1261 caacttttcc tagtttatct gatgttttaa atgcagtccg taagttttcc atagttccct
     1321 ccaatttcct atactaaata tatttagtat acttcatata cttaatatat tcgatatatc
     1381 taatatactc caaattgata agaattcaga ctttataagg aatatagtgg atatactaaa
     1441 tatatttgct atattcagta tatcagatat attcaaaatg tcaaaatata tttgtgcgtt
     1501 ttgcgttgac aatttagagt gaaaagaggt aaacttaatt ctatagaaac cacagataat
     1561 tcactattta caaagtagca aaagcagtgg tactctttaa acagaaaaat tacataaaaa
     1621 aaagagacgg aaataattga ttttagcaga atcaattatt tctgaatcac atggttagga
     1681 catgtgttca cgctcgtctc aagaatatgt aagtagctac caactactta tattaaaagt
     1741 tgatcggata ccttttccga ttgcctttat tctaccaaaa aaaggcgagc aactcaacag
     1801 aagaacgttt atttagtgta cttaaattaa atattcttaa acactgaaga gagaacacat
     1861 actatggctg agattaaagc taaactgtgt tctctttttg tttgagaaag gacgttacaa
     1921 tcgatgttga gcgaaattta ttcagctatt cttaaaaacg gcttacgtac atacaaatat
     1981 cgaaacagca ccatgaaacc tgcaggtcat attgattcca gtaggagtgg tgctatcttt
     2041 gcgtaccgta gcaagcaatt aatgaatgtt gggcgtggta tggtcattac ttcggaagaa
     2101 gctattttag agaacgaaaa gaaactaacg cattggacac ctaataccta tcgctttggt
     2161 acttatgcgg atgattatcg aacagtggtt aaaggtcatt ctgagaaaaa cttaagtcaa
     2221 atcaacacat ttgtagttga tatcgattca aaagagaacc atcaaggcga aattatttta
     2281 gcctgtttag atcaagtggg ctacatgcca acgctaattt tagaatcaga tcatggttat
     2341 caagtttatt ttgtactaaa gacaccaggc tatgtcacaa agaaaagcaa tttcaaggtg
     2401 atcgatgtag caaaaaaaat ttcaaaaaca attcgtctac agttggctga aaaattgtcc
     2461 ggagtggatc taggatgtaa ccacttcgga attgctcgat tcccacaaga aaataatatt
     2521 gtttttaaag aaatgaacta tcagtattct tttgctgact ggattcaatg gtcgatgaag
     2581 cttgaatcag atcaaaaaac aaaagaagat cgagaacgaa aactaattgt ctttcctgag
     2641 aaaaaagaaa ttcgtcaagt agatgaaccg tggttcgata tgttacttca taaagcaaac
     2701 atcgtcggcg gagaaggacg tcttggtcga aataatgtga ttttcacgct ttctttagct
     2761 tattactctt caggttatgc attggatact tgcgaataca atatgttcac attcaacgaa
     2821 cggttacagg aaccgctatc tgaagcagaa ttagtaaaga ttgtacgtag tgcttattct
     2881 ggtaattatc aagcagcaag cagagaattc attattgaat tgtgccagca atgggtttca
     2941 ccaaccttaa aaaataatga tctgttcatt caacgacgtg gctggtggaa atttaaaaag
     3001 ccacgagatc aaagaaaata tagtcataaa aatgaatgga aagaagatct attggcttat
     3061 ctaagcgaaa aaagtcttgc tagtgagcct tatttgaacc tgtcaaaaaa agaattggct
     3121 tcacaactaa cgatgcccaa gcgaacactt gataagatct taaatgagtt acgagaggag
     3181 aataaagtct tctacaaggt aacacgagga agaaatggcg gaatgatcat tgcttcagtc
     3241 aaaacgttgt tcgcgagggt tattcaacta agtaaagaaa agagactaga ttattcaaca
     3301 aggatcacag aggtatttgg actcaacgag agcttagtag aagagacatt tagacaatta
     3361 tcaaccccct tgaaccctct taaagaagtg aatctttttg aagtagatac aggttgaaaa
     3421 ataaaaggtg caaattgcct tatacaatat atctatgata cttctgtagg tgttgctccc
     3481 tttgcctagc tacgtgtagg tggtatactt ataactgcgt atgcagtctt atgtatcatg
     3541 gaggaagttg tatgtcgtta aaaaattatg tctattcaca tcctgttaat gtgtttatca
     3601 ttggtcgttt gggattatct gtggaagtgt tctgtgagct ttatggtttt aagcagggga
     3661 ctttgtcttc ttgggttacc agggaaaaaa cagttgcttc tttgccgatt gagtttcttc
     3721 atgggttgtc cttagcttct ggggagacta tggatcaggt atatgattgt ttgtgtgtgt
     3781 tagagcagga gtatattgag tataaaatag ctaacgagtt aagaaaaagg aagaagtata
     3841 tccagtagta gtttttattt actcttaatt gtcaaattaa gttagacaaa tcatcaatac
     3901 ttacgtaact caaaaatact tccaaa
//
LOCUS       DAXLPY010000129         3834 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.132, whole genome shotgun sequence.
ACCESSION   DAXLPY010000129 DAXLPY010000000
VERSION     DAXLPY010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.132"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(34..1353)
                     /locus_tag="ACF3UF_002658"
     CDS             complement(34..1353)
                     /locus_tag="ACF3UF_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3672712.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1350..2003)
                     /locus_tag="ACF3UF_002659"
     CDS             complement(1350..2003)
                     /locus_tag="ACF3UF_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3672713.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2291..2811
                     /locus_tag="ACF3UF_002660"
                     /pseudo
     CDS             2291..2811
                     /locus_tag="ACF3UF_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(2809..3528)
                     /locus_tag="ACF3UF_002661"
                     /pseudo
     CDS             complement(2809..3528)
                     /locus_tag="ACF3UF_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(3479..3688)
                     /locus_tag="ACF3UF_002662"
     CDS             complement(3479..3688)
                     /locus_tag="ACF3UF_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672714.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            complement(3670..3738)
                     /locus_tag="ACF3UF_002663"
                     /pseudo
     CDS             complement(3670..3738)
                     /locus_tag="ACF3UF_002663"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
BASE COUNT         1231 a          725 c          478 g         1400 t
ORIGIN      
        1 tttttcaata actattgcaa aattatatct taattaagaa aatattttta ttttaaagat
       61 aaaaaattct tcatcctgca atactttata ttctatattg taattattca gaatattact
      121 tacaatatat aaacctaatc cattactatt ttccttattt aaatcaaatt taacatcaaa
      181 tattttatcc atattcgaaa ttttattgtt accgtatgaa ttctctatat ataaccaatc
      241 attaactatc ccaatattaa ttaccccatt tacatcagta tattttaccg cattactaat
      301 caaattagat agaataatct ttaaagctgt ttttcctata taaacattct cgtctaatat
      361 ataattattg acagttattt tcttttgatt tgctaatatt tcatactttt ttaatatgtc
      421 ttctaatgta tcatttattt tcaaatattc ttcatcatta ttcaaatttt ctatagaatg
      481 aactgataat atttgagaaa tattttttgt taaactatca acgatttcaa tacattcatt
      541 aatataaata tctctttctt tatattttcc aatattgtat ttcatgtttt ccagtattat
      601 tttaagacta gcaagagggg ttttaagttc atgggatgca cctttaaaaa agtcatattt
      661 taacttttct aattttaaaa tttctttatt tttaaattcc aaatcgtcaa ttgttcttaa
      721 taaagtagaa tacaaatcat taatttgttg ttttaattct ccaacttcat cattagagct
      781 aacttttaaa ctcatttttt tatcaagttt catcatttta tcagtaacaa tttttatttc
      841 ttgtatatta ttttttattg attttgcata aattaaagaa ataatagcag aaaataaaat
      901 tgatattaat aaagaatatg gtaaaaattt aaggcttaaa tctttcgcat ctttttgcat
      961 atcagctgta gaaacaaatt gtagatttgt ttttttacca tcattaagct ttatttctct
     1021 ttcttcaatt atcaaagaat tactatcact ttctaaatta acatttatat tatctttgat
     1081 ttgtatttca ttcttattat ttttttcttt tatgaatact tttatttcac tactcttgga
     1141 ataaaactcc aaagtttgtt ctatatattt tatttctttt ccattcatat tactagaaat
     1201 ttcatttgcc atattatgaa tcttttcttt tctcgtctcc aaatatgttt taggaaagat
     1261 aaaaaaaatt aatgaatgaa ctaatataat tattattcca agaacagaaa atatttgtat
     1321 gaacattttt ggaaatatct ttaatttttt cattttctct ccaatttata tcctacattt
     1381 cttatagtag ttatacagtc taattgtaat ttttttctaa gttcttttat atatacatct
     1441 attactcgat cataaggagt ttcttcgcta tctttccata cataatcaat aatttgcatt
     1501 cttgttaaca cttgtccatt attatccaat aaacatttta atacttctag ttcttttgca
     1561 tttacatcta tttcttcacc atttatttta gctgtatagc tattaaaatt aaccgataga
     1621 tccttatatt caaacttctc taaatgtcca taattcttct taattaaaga atctattcta
     1681 gcttttaaga ccggcaatga aaatggcttt tctacatatc cgtctactaa attagtaaat
     1741 gcatcaattt tatattcttc atcactaaat gcagtcaaga ttagaattgg taaattgctt
     1801 ttctttctaa tttctttcaa cacttctaaa ccatttataa aaggtatctg aatgtctaag
     1861 ataaccaaat ttatatcgct attaaatttt gacaaggctt ctcttccatc tttagcttga
     1921 ataacagtat atccaaattc tgaaagatat tcacttattc cctctcttat catattatca
     1981 tcttcaacag ttaatatttt catatatacc tccacttaag cctatacact agatattata
     2041 cagcatatta tggctctata atatctagtg ttggtgacgc cttctgttgc caatactttt
     2101 tctttttttt aataaatgca aacagacacc ttgaaatcct ttagaaaaaa ggcttctata
     2161 atattttgtg ttgttggaaa atcgaaggcg attttctact aacacttttt cttcgtttca
     2221 actcaaaaag agactcactt ttggtaaaat ttagtcgacc aaaacatcac cctaccaaag
     2281 gagtcgctct atggataatc atactagaaa attactcgga ttaacagata aacatttatt
     2341 ttttgatgaa gaatggctga ttgaaaaaga atataaaggc gttcaagcgc agtttattaa
     2401 agggagattg gatgactcac cttcccattg tgaacactgt ggatcgattc gtattatccg
     2461 caacggttcc tatacgacac gtactcagat gttgaaagtc aaagaaaagt tgactatttt
     2521 agaattaaaa cgtacccgtt ttctatgcta tgattgtggg cagacctttt ctgcgaaaac
     2581 ggacttagtt gatgaacatc atcaactaac aaaggaactg aagcaggcga ttctcataga
     2641 actgtacgaa aatcaatcac gtaatctgaa aatcagaaga agtaccgtcg gctcaagcga
     2701 tattggaaac tcttactcaa agattccacg acattggagc cgctcaaacg gcattatcat
     2761 cgactgttta aacgaccaat tagtcaaaca gaaatcgtcg atgaaccgtt gtgcacaatg
     2821 gtgtcctgaa cgtacagcga caccttccat atccagagca gtcgccacat cacggggatg
     2881 gatgccatcc aaattaaaag caaccacgcc agtatgatgt tcaggatctt gcggtccgta
     2941 aatggtgata ccgccgatcg cttgtaattt aggtaaaacg taggcaacca gttcttgctc
     3001 ataacgatga atattctcca taccaatctc attcaagtaa tcgattgctc ctgcaatgtt
     3061 cggagtacca gcttcaaatt tccatggcag ctctttccat gaactatcgt aaagattgac
     3121 aaaatctatc atttcaccgc cgaattcgac tggctccatt tgttctaaca attgacgttt
     3181 gccatataat acaccgattc ctgtcggccc gcacatttta tgcccgctaa aggcgaaaaa
     3241 atctgcatcc aacgcttgta catcaactgt catatgcggt gctgcttggg caccgactgg
     3301 actatcctca actacaacag cctgttcaac cctcagccgt ttcaagcaca acaaataacc
     3361 ttctggatct ggtttgccga cctgaagatc atcgatcgtc acaaaggaat caattttttc
     3421 cttaatcatc ggatgtgctt caaaaaaata gtctagctcc cgcagttcag aattgagact
     3481 actccgattt tccagtgctg ctgatccgct gctcaaaatg ttcagcatcc actggtctcc
     3541 caaccgcttg acttatccct tcataaaagg acagttctgc tgccgtccca acaccttgtt
     3601 gatagtctgc aaaaggaatt ttatagccga actgctccag taaataggct tcagtaaata
     3661 gtgatgaata ctctcgtaaa acatccattc actgtcaatc atcgtcccat caaaatcaaa
     3721 aataagtgct ttggtcatct tctttccccc ttacccaaaa caagcaaaag ctgtgtcctg
     3781 ctctctctac agtatcagca taaaaactgc cgtctgaaaa gtcaaaggtg aaag
//
LOCUS       DAXLPY010000130         3654 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.134, whole genome shotgun sequence.
ACCESSION   DAXLPY010000130 DAXLPY010000000
VERSION     DAXLPY010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.134"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..776
                     /locus_tag="ACF3UF_002664"
     CDS             <1..776
                     /locus_tag="ACF3UF_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672715.1"
                     /translation="THEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLK
                     NAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYG
                     CEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSF
                     KIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGR
                     SVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            883..936
                     /locus_tag="ACF3UF_002665"
                     /pseudo
     CDS             883..936
                     /locus_tag="ACF3UF_002665"
                     /inference="COORDINATES: protein motif:HMM:NF019662.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            970..2346
                     /gene="tet(L)"
                     /locus_tag="ACF3UF_002666"
     CDS             970..2346
                     /gene="tet(L)"
                     /locus_tag="ACF3UF_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFD3672716.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2910..>3654
                     /gene="mobV"
                     /locus_tag="ACF3UF_002667"
     CDS             2910..>3654
                     /gene="mobV"
                     /locus_tag="ACF3UF_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HFD3672717.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGL"
BASE COUNT         1163 a          555 c          754 g         1182 t
ORIGIN      
        1 cgacacatga aattatactt tctttcttag ggaaagtaca aatggaagtg attagtgcac
       61 tgttgcaaga aaagtatcat gtggagatag aactaaaaga gcctacagtc atttatatgg
      121 agagaccgtt aaaaaatgca gaatatacca ttcacatcga agtgccgcca aatcctttct
      181 gggcttccat tggtttatct gtatcaccgc ttccgttggg aagtggaatg cagtatgaga
      241 gctcggtttc tcttggatac ttaaatcaat catttcaaaa tgcagttatg gaagggatac
      301 gctatggttg cgaacaagga ttatatggtt ggaatgtgac ggattgtaaa atctgtttta
      361 agtatggctt atactatagc cctgttagta ccccagcaga ttttcggatg cttgctccta
      421 ttgtattgga acaagtctta aaaaaagctg gaacagaatt gttagagcca tatcttagtt
      481 ttaaaattta tgcgccacag gaatatcttt cacgagcata caacgatgct cctaaatatt
      541 gtgcgaacat cgtagacact caattgaaaa ataatgaggt cattcttagt ggagaaatcc
      601 ctgctcggtg tattcaagaa tatcgtagtg atttaacttt ctttacaaat ggacgtagtg
      661 tttgtttaac agagttaaaa gggtaccatg ttactaccgg tgaacctgtt tgccagcccc
      721 gtcgtccaaa tagtcggata gataaagtac gatatatgtt caataaaata acttagtgta
      781 ttttatgttg ttatataaat atggtttctt gttaaataag atgaaatatt ttttaataaa
      841 gatttgaatt aaagtgtaaa ggaggaatta attatgaagt gaaatgaatg taacagggtt
      901 caattaaaag agggaagcgt atcattaacc ctataaacta cgtctgccct cattattgga
      961 gggtgaaatg tgaatacatc ctattcacaa tcgaatttac gacacaacca aattttaatt
     1021 tggctttgca ttttatcttt ttttagcgta ttaaatgaaa tggttttgaa cgtctcatta
     1081 cctgatattg caaatgattt taataaacca cctgcgagta caaactgggt gaacacagcc
     1141 tttatgttaa ccttttccat tggaacagct gtatatggaa agctatctga tcaattaggc
     1201 atcaaaaggt tactcctatt tggaattata ataaattgtt tcgggtcggt aattgggttt
     1261 gttggccatt ctttcttttc cttacttatt atggctcgtt ttattcaagg ggctggtgca
     1321 gctgcatttc cagcactcgt aatggttgta gttgcgcgct atattccaaa ggaaaatagg
     1381 ggtaaagcat ttggtcttat tggatcgata gtagccatgg gagaaggagt cggtccagcg
     1441 attggtggaa tgatagccca ttatattcat tggtcctatc ttctactcat tcctatgata
     1501 acaattatca ctgttccgtt tcttatgaaa ttattaaaga aagaagtaag gataaaaggt
     1561 cattttgata tcaaaggaat tatactaatg tctgtaggca ttgtattttt tatgttgttt
     1621 acaacatcat atagcatttc ttttcttatc gttagcgtgc tgtcattcct gatatttgta
     1681 aaacatatca ggaaagtaac agatcctttt gttgatcccg gattagggaa aaatatacct
     1741 tttatgattg gagttctttg tgggggaatt atatttggaa cagtagcagg gtttgtctct
     1801 atggttcctt atatgatgaa agatgttcac cagctaagta ctgccgaaat cggaagtgta
     1861 attattttcc ctggaacaat gagtgtcatt attttcggct acattggtgg gatacttgtt
     1921 gatagaagag gtcctttata cgtgttaaac atcggagtta catttctttc tgttagcttt
     1981 ttaactgctt cctttctttt agaaacaaca tcatggttca tgacaattat aatcgtattt
     2041 gttttaggtg ggctttcgtt caccaaaaca gttatatcaa caattgtttc aagtagcttg
     2101 aaacagcagg aagctggtgc tggaatgagt ttgcttaact ttaccagctt tttatcagag
     2161 ggaacaggta ttgcaattgt aggtggttta ttatccatac ccttacttga tcaaaggttg
     2221 ttacctatgg aagttgatca gtcaacttat ctgtatagta atttgttatt acttttttca
     2281 ggaatcattg tcattagttg gctggttacc ttgaatgtat ataaacattc tcaaagggat
     2341 ttctaaatcg ttaagggatc aactttggga gagagttcaa aattgatcct ttttttataa
     2401 caggaattca aatctttttg ttccattaaa gggcgcgatt gctgaataaa agatacgaga
     2461 gacctctctt gtatcttttt tattttgagt ggttttgtcc gttacactag aaaaccgaaa
     2521 gacaataaaa attttattct tgctgagtct ggctttcggt aagctagaca aaacggacaa
     2581 aataaaaatt ggcaagggtt taaaggtgga gattttttga gtgatcttct caaaaaatac
     2641 tacctgtccc ttgctgattt ttaaacgagc acgagagcaa aacccccctt tgctgaggtg
     2701 gcagagggca ggtttttttg tttctttttt ctcgtaaaaa aaagaaaggt cttaaaggtt
     2761 ttatggtttt ggtcggcact gccgacagcc tcgcagagca cacactttat gaatataaag
     2821 tatagtgtgt tatactttac ttggaagtgg ttgccggaaa gagcgaaaat gcctcacatt
     2881 tgtgccacct aaaaaggagc gatttacata tgagttatgc agtttgtaga atgcaaaaag
     2941 tgaaatcagc tggactaaaa ggcatgcaat ttcataatca aagagagcga aaaagtagaa
     3001 cgaatgatga tattgaccat gagcgaacac gtgaaaatta tgatttgaaa aatgataaaa
     3061 atattgatta caacgaacgt gtcaaagaaa ttattgaatc acaaaaaaca ggtacaagaa
     3121 aaacgaggaa agatgctgtt cttgtaaatg agttgctagt aacatctgac cgagattttt
     3181 ttgagcaact ggatccagga gaacaaaaac gattttttga ggaaagttat aaattatttt
     3241 ccgaacgata tggcaagcaa aatattgctt atgcaacagt tcataatgat gagcaaaccc
     3301 ctcacatgca tttaggtgtt gtgcctatgc gtgatggaaa actgcaagga aaaaatgtgt
     3361 ttaatcgtca agaactgtta tggctacaag ataaattccc cgagcatatg aaaaaacagg
     3421 gttttgagtt gaagcgtggt gaacgtggct ctgaccgtaa acatattgag acagctaaat
     3481 ttaaaaaaca aactttggaa aaagagattg attttctaga aaaaaattta gcagttaaaa
     3541 aagatgaatg gactgcttat agcgataaag ttaaatcaga tttagaagta ccagcgaaac
     3601 gacacatgaa aagtgttgaa gtgccaacgg gtgaaaagtc catgtttggt ttgg
//
LOCUS       DAXLPY010000131         3652 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.135, whole genome shotgun sequence.
ACCESSION   DAXLPY010000131 DAXLPY010000000
VERSION     DAXLPY010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.135"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..885
                     /locus_tag="ACF3UF_002668"
     CDS             <1..885
                     /locus_tag="ACF3UF_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3672718.1"
                     /translation="SLVDMYVSDYFLKAEASKCITGLYTANEFNHVTPKQLDDKSVVI
                     LCSHGGNTAETVKAGEVAQARGAVTVGLTHNKTADLLKVSDHSFLYEWGDDAKIVNNP
                     MAIILDLTVSLVNVTETFEHYGKFREGMKVIDTVIENGIKQVQDRIKVFADKYKDETM
                     FYILGSGPSYGHAYGFSICSLMEMQWLDSTSVHSGEFFHGPFEVTDKDTNFILLMSIG
                     RTRALDERAKRFLDKYAERVEIVDAKELGLDMISDEVSEFFNPILFYSILSEYRSALA
                     DVRNHDLDVRRYMGKVEY"
     gene            953..1711
                     /locus_tag="ACF3UF_002669"
     CDS             953..1711
                     /locus_tag="ACF3UF_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HFD3672719.1"
                     /translation="MYPGGNSLNFAVFAKKLGHESSFMGVFGSDEEAAHVLSAIKEIG
                     LDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREYPIQLTEEDREYLNQFELIH
                     MGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAIDKVDFGFFSIEDFSDEEVKQ
                     FLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEEPVDTMAAGASFLTAFLLYF
                     LEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            1779..2489
                     /locus_tag="ACF3UF_002670"
     CDS             1779..2489
                     /locus_tag="ACF3UF_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3672720.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            2525..>3652
                     /locus_tag="ACF3UF_002671"
     CDS             2525..>3652
                     /locus_tag="ACF3UF_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFD3672721.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1208 a          548 c          814 g         1082 t
ORIGIN      
        1 tcgctggtag atatgtatgt ctcagattat tttcttaaag ccgaagcatc gaagtgtatt
       61 acaggcttat atacagcgaa cgaatttaac catgtaaccc caaagcaatt agatgataaa
      121 tctgttgtca ttctatgttc tcatggagga aatacagcag aaacggtaaa agcaggagaa
      181 gtcgctcaag ctagaggagc tgtgactgtt ggtctgactc ataataaaac tgcggattta
      241 ttaaaggttt ctgatcatag tttcctttac gaatggggag atgatgcaaa aatagtcaat
      301 aatcctatgg ccatcattct tgatttaact gtatctttgg tcaatgttac cgaaacattt
      361 gaacattacg gtaaattcag agaaggcatg aaggttatcg ataccgtaat tgaaaatggc
      421 attaagcagg tgcaggatcg tattaaagtg tttgctgata agtacaaaga tgaaacaatg
      481 ttttatatct taggtagtgg accatcatat ggacatgctt atggtttttc aatttgctct
      541 ttgatggaaa tgcaatggct tgattcaact tctgttcatt ctggagaatt cttccatgga
      601 ccttttgaag taacagacaa agatacgaat tttattctct tgatgagcat tggacgcact
      661 cgtgctttag atgaacgggc aaaacgattc cttgataaat atgcagaaag agtagaaatc
      721 gttgatgcaa aggaactagg attggatatg atatcagatg aagtttctga attcttcaat
      781 cccattttat tctacagtat tctttcagaa tatcgttcag ctttagcaga tgtacgcaat
      841 catgatttag atgttcgtcg ctatatgggg aaagtggagt actaggagga ttaaaatgaa
      901 ggtattaggc ttaggtgata acgtcgtcga taaatatgaa aatctgggaa ttatgtatcc
      961 tggaggaaat tcattgaatt ttgcagtttt tgcaaaaaaa ctgggacatg aaagtagctt
     1021 tatgggagtt tttggctcag atgaggaggc agctcatgtt ttatcagcaa taaaagaaat
     1081 aggactggac aacagtcact ctcgctttga aaaaggcgag aatggctgtg ccagagtgaa
     1141 gattgatgag ggcgaccgga ttttccttgg cagcaattcg ggaggtgtta ctcgtgaata
     1201 cccgattcag cttactgaag aagacagaga atatttaaac cagtttgaat tgattcatat
     1261 gggattatat agccatgtca atcatctatt agaagagtta caaaatgttt ctggaaagat
     1321 ttcttatgat ttttctgacg actttacgga agaagaggtt cagcgggcaa ttgataaagt
     1381 tgattttggc ttcttttcta tagaagactt ttccgatgaa gaagtaaagc agtttttgat
     1441 gaagcatttt tgtgagcgaa atgatgtatt gattgcaacc cgaggagaaa aaacggctat
     1501 tggttatgat ggagcaaagt tttatgaagt gaaccccgtg ctagaagaac cagttgatac
     1561 aatggcagcg ggagcttctt tcttaacagc tttcctactt tattttctcg aaggggacga
     1621 tatagtcacc gcgatgaaaa aggggaatga atttgctggg aagtcttgtc tggttgacgg
     1681 ttcgttcggc tttggtattc attacgattg agcttgtttt aaattcctgc atttgataac
     1741 ctaaagaaag aaatcccggt aaagtggagg ttaaaaaaat gctggataca aatgcacaat
     1801 taccattgta cttacaatta aaagaaatat taaaaaataa aatcaataca ggggagtatc
     1861 ccgagaatac gaaaattccc gctgaatcag agctgataga aagttatgag gtcagccgaa
     1921 tcacagtgag aaaagcagta gaagaactgg tagaagaagg gtacctactt aaaaaacaag
     1981 ggaaaggaac ttttgtcaac cggcataaag tttttcgtaa aattgaatat attatgggtt
     2041 tcagtgagag ttgtaaatct aatggtttta caccgactag cattgttttg gaacgcaaga
     2101 tcattccagc aactgaaggg atggcaaaaa aactcgatat cgctcaaggt gatgatgttt
     2161 tatatatcca gagaaagcga atggcggata acatccccat tatgttagaa aacaattatt
     2221 tttcttatga aagatatagt ttcttaatgg aggaagagct gactgattct ttgtatgaag
     2281 tacttaaagt ccaaggtacc ttagccatca atcctgggga aactgcactt gaaattgtca
     2341 cagctgatga ccaaattgcc aaaataatgg aagtagctgt tgggacgccc tttttcttta
     2401 tggatacttt aatcaacgat caaaacaaca taccaattca tgtaggtaat caatattacc
     2461 tgggagaagt atatcgtttt tacttatgat ttcctgtttg gatttcaagg agtagatttt
     2521 atttatgaag caaatattgc ggtcaaaaat gatttttgat ggagagcagc cacctttcaa
     2581 aggttatatt gtaatcaatg aagggatcat tgaaaaggtg gaaaacaact ggaattacag
     2641 tgatctatta aatgaaaaca cggaattaat tgcttatgat gatcaattcg ttatgccagc
     2701 aattcatgat aatcatgtat ttttcagtgg ttatttggct atgaatgctg gcatagattt
     2761 aagcgataca tcttcagcta acgaggctgt agagcgtatt aaagctgtaa tgaaccataa
     2821 aaaagcagat gaaccaattt atgctcatgg ctgggatgct gccctgtgga aaactgaccc
     2881 atcagaagag ctattgaatg aaataaacca ctttggtcca atcacagcga tcgacaaaaa
     2941 tcgcagccat tgttggatga atgctattgc taagcagact tatggtttta cagaaaaaga
     3001 aaccagtgct gaaagtcgag tattattaat taaggaaatg ctagcaaaca aaaagctttt
     3061 agcagaggtt tacgctgaat ttgaagcatt actgctttca aaaggtgtta tatcaatgaa
     3121 agaaatcgtt tttgatgacg cagaatttct ttctaatata cctcagagga aaatacttag
     3181 taacctatat gtgcaggcag tccaagaacc tctacagcat gaacttctat atgagtataa
     3241 ggaaaaagtt ttccctgaaa aggtccgctt tggtggagtg aagatcatgg tagatggtgt
     3301 tgttgcggat agaagtggag atatttacgg tgtttatcag tcaggagtag cttcacccga
     3361 gattgactat gaggcaatta aagcagaagt tgctgcattc aatgaagtag agattccttg
     3421 ctgtttgaca acggaaggag ataaagcggg ttataaagct gcgtcaattc ttgtcgaatt
     3481 tggaaagcgg ttacctgaag gcgtttttaa ttcgattagt gatttggaaa tggttactca
     3541 aaagacagca gaaaaaatga acgaaggaca agtagtagca gaggtatatc cacaaattct
     3601 cggcttgaat caaacgttag aagaggctta catgtcaact gttataaaaa at
//
LOCUS       DAXLPY010000132         3542 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.137, whole genome shotgun sequence.
ACCESSION   DAXLPY010000132 DAXLPY010000000
VERSION     DAXLPY010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.137"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..342
                     /locus_tag="ACF3UF_002672"
     CDS             <1..342
                     /locus_tag="ACF3UF_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HFD3672722.1"
                     /translation="SWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGLHDQ
                     LEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMIRKR
                     LLLEAEKAVKE"
     gene            339..2658
                     /locus_tag="ACF3UF_002673"
                     /pseudo
     CDS             339..2658
                     /locus_tag="ACF3UF_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
     gene            2719..3261
                     /locus_tag="ACF3UF_002674"
     CDS             2719..3261
                     /locus_tag="ACF3UF_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672723.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            3339..>3542
                     /locus_tag="ACF3UF_002675"
     CDS             3339..>3542
                     /locus_tag="ACF3UF_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672724.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWR"
BASE COUNT         1299 a          514 c          708 g         1021 t
ORIGIN      
        1 tcgtgggata tcaatgatat agacatacat tgtacacatg cggacttgga tcttaaggct
       61 ttacaaattg attatgatta tttcctacca gatgaatatg ctagaaatct ctatcatgga
      121 ctgcatgatc aattagaaga aaaaaacgaa gaaaatatgt tttataaaat cgttcaatct
      181 tttgagaatg agacggctaa aaaattgtta attcaatttt acgaagaaca agcaacggat
      241 cgtcttcaag aatatgttga aaagttgatc aaaaatgaag aaatttctga aatgattagg
      301 aaacggctgt tattggaagc tgaaaaggcg gtgaaagaat gatcattgga ggaattttct
      361 ctggcatagc cgactggtgg tcaggtttat tcggagaagg ggatgcagat cccaaaaccg
      421 taacgaaagt cttacaagat tatggtaatt atctgcagta tcaagatgta ttcagttgga
      481 tttgtaatac ttttttatgg ggattgatca aagggttata taatctcaat actttattag
      541 aaaaaacaat ttatcaaagc tttgatttaa aagacttatt gaacgccgct ggtgttaatg
      601 aactatttca aagtttgatt agtaaggtat tggctctttt ttgtgtcgtc acattaattt
      661 atttaggctt gaaatttttt atgagtaaac acccaccgaa agtcaaaaat atcttggtta
      721 atttatttat ggccatgatc ttgatttttg gtggtagttc tttaatcgat gaagggttaa
      781 atatcagtaa aaacttttat ggagacgtca ctgcagcaaa taaagcagat aaaacgggtt
      841 cacctgcttt tcaaattatt caaaataatg tgattgatgt cagtacatta ctagcgactg
      901 acccgaataa agtagaatcc ttaccaacag ataaaagaaa tgctttaaca gcgaaaaatt
      961 tcaaaacagc gaatatcaat gggattatta cacctgatca agctaagaaa atgtctgaat
     1021 caagtgatat tagtacagta caaaaagatc ggttaaaggc attacagtat cgactagagt
     1081 tagacgataa tgggaaagaa atccctgttc aaattagtga tgaaggttta gcaaaatatg
     1141 tgtatacgtc aggctatcgt cgatacatta gtagtccagg gattattttg gctggggaat
     1201 cttctttgtc ggtagcctat ttatttattt tgtttacaat cgttacttgc attattgagc
     1261 tagtatttaa aaaattctat ttagtaattg ccgcgtcaac ggactttgag acaggacaac
     1321 ggatgaaaag tgcgatagaa gatatttctc aatccttctt gttattggcg tttacgattt
     1381 tagaattacg aatctataca ttaatgcttt caggtatcgg tgatttgcat gcggtaggaa
     1441 agatcaatgg attcttgtat gttgttgctt taattgtgct aactattgcg ctattcaaag
     1501 gctctcaatc ggttacgaag attttcggtg ttgatacgag tctgaaaaac ggcagcaatt
     1561 ctcttcttag catgtttgcc ttaggaaata ttgcgaaaaa tgtgggtagc ggagctaaaa
     1621 accttgcaag tgctggtaag agtggtttaa gccatttaaa tgatattcgt aagaatggat
     1681 ttggccatcg aaaagatatt acccatgata acggggaaga acaatcagac gataaagcta
     1741 caactgtacc taatagtaag aagacagttt ccgaaatgtt cgggaaagcg aaaaatggtg
     1801 tttctaaagc cgcagaaggt cttggttacg tcaatgaacg tgggttaaaa ggaacagttg
     1861 aagatcttac agaaaaagcc aaagacacct tagaagagaa attagacggc acgagagcta
     1921 aagaatttgc tgaagctgtg aagaatccat ccgaagcact agaaaaacaa aaagaaaaag
     1981 cttcagcagt caaagaagga ctaaaagatg cgtatggtga aggacaagtc aatgcagcag
     2041 tgaaggcaaa tacaacaagt gaaaaagaaa atcaagaagg tgcagcgatt ccttcagcca
     2101 aagatcacca agatgagtta cattctaacg aaaattcgat cggagaaaaa gattcagaag
     2161 aaggacaaca tggtcagtta ccaaaaaccg atccagaaca atatcgttat aaatctaaca
     2221 ttaattctga aaacgaaaaa cgcatttcag atttaccaaa acgaaatcaa gaagtacaaa
     2281 cggatgagga ttccatcgat ctgccaaatg ataatggcat cgaagttgga actgaaaaat
     2341 caacgaaaat tggtttgcct aagacacaaa atttaccaat gaaagggtac tgttcaaatg
     2401 aaatcaagtc gtttgcctga aaatggaaat ctgacaactg tttcttacaa tttagctgaa
     2461 agtggtgaaa cagagaatgc gtccgttcaa aatattgtga caaaagaagc tgcacctaag
     2521 ccaatcaata aagttcataa tggatacaga ccagcaaacg tagcatttac tgcaccgaca
     2581 aaaataaatg tgacaagaga aactaaaaac aggaacaatg aattgaaaga acaactattg
     2641 aaggatatca aaccataaaa ggcctattta agggcctttt tctttataaa acaagtttaa
     2701 aatggaaagg agaaaattgt ggaggatatt ttaatagcta cgtttataac tgcactggga
     2761 gcatttttaa cgatatttgt ggtgactatt aaaggattta aagatacgga tagtttacaa
     2821 aaagatcatc agtctatttt agatggtcaa aaaacacata ccgaaagcat tattgtacac
     2881 ctttcagaag gattcactta tttgaaagat gctatgccca cattcacagt aaaattaacg
     2941 gaaatatttc attctgttga gcaaatatcg tcagaattga aagagcaaag acaacaaaaa
     3001 gatcgtcaac ttggctcact taattttagg caagaaacga tacaagaatc attggagaat
     3061 gtaaatcgat taaacgatga aatgcaacga gttcatttgg aaaatgaaga attacgcgca
     3121 caaaattatg atttaattca aaagaaaaga aatctggaac aaaaaattgt tgaattaaaa
     3181 gaagaaaatc gtcaattgaa ttatcaatta cgacgaggaa aaaatcgttc tcgtgattta
     3241 ggaaatgaat tagagttgta atatttagaa aaacgctgtg agaaatcaca gtgtttttta
     3301 tttctaaaaa tacaaaatat aaggggtatg gttatattat ggataaatac attcatatga
     3361 aaaatcctcc aagatttagt ggggaatgga agtttttcgc ctttttcttt ttagatctat
     3421 taacgcttgg tggctgcttt ttttgggcga aaatagtcaa taatcttgtc cacttaccac
     3481 tcttttttgc actcttgaat tatggattat ggcttgcgat agcgttagtg attgtttggc
     3541 ga
//
LOCUS       DAXLPY010000133         3390 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.138, whole genome shotgun sequence.
ACCESSION   DAXLPY010000133 DAXLPY010000000
VERSION     DAXLPY010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.138"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            647..964
                     /locus_tag="ACF3UF_002676"
     CDS             647..964
                     /locus_tag="ACF3UF_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFD3672725.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="ACF3UF_002677"
     CDS             complement(1055..1420)
                     /locus_tag="ACF3UF_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672726.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="ACF3UF_002678"
     CDS             1628..2110
                     /locus_tag="ACF3UF_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672727.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="ACF3UF_002679"
     CDS             2307..3197
                     /locus_tag="ACF3UF_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFD3672728.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1172 a          519 c          619 g         1080 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac
//
LOCUS       DAXLPY010000134         3328 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.139, whole genome shotgun sequence.
ACCESSION   DAXLPY010000134 DAXLPY010000000
VERSION     DAXLPY010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.139"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..354
                     /locus_tag="ACF3UF_002680"
     CDS             <1..354
                     /locus_tag="ACF3UF_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HFD3672729.1"
                     /translation="RATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSS
                     LETPSISAKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKLESLQ
                     PPIPPIPKTPKLPGL"
     gene            791..1108
                     /locus_tag="ACF3UF_002681"
     CDS             791..1108
                     /locus_tag="ACF3UF_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672730.1"
                     /translation="MEKTKKLQLEDFTENEFFGTQEQQYLKAQVREELKEQGFIIDSS
                     FEGDFKTWIGVYARPKDKPTYLDPQNDKEAEEQEQYSINGFKQDFSEWFEWEIKNLKI
                     KEM"
     gene            1147..1644
                     /locus_tag="ACF3UF_002682"
     CDS             1147..1644
                     /locus_tag="ACF3UF_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HFD3672731.1"
                     /translation="MKYIKNVETLEELKKAYKKLALKLHPDCGGSNEEMAQLNNEYDE
                     LFVKLKNTHKNKDGETYTKETTETPEQFKDIINQLFNLKMDGVSIEIVGTFIWLTGNT
                     KPYKDDIKALEFRYSPKKYAWYKAPSDYKKRSRKNYDMDTIRGMYGSQKVKEDKEEKK
                     YLQAN"
     gene            complement(1734..1925)
                     /locus_tag="ACF3UF_002683"
                     /pseudo
     CDS             complement(1734..1925)
                     /locus_tag="ACF3UF_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            1849..2121
                     /locus_tag="ACF3UF_002684"
     CDS             1849..2121
                     /locus_tag="ACF3UF_002684"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672732.1"
                     /translation="MLNALELNRGFLFLWSFSLKIILARKNGTLLEALRAELPAFEQT
                     IVPEFKGAVRAVLKKIHRPSIGVKMGEIANYSSTSSPMGQLKKMFG"
     gene            2292..2870
                     /locus_tag="ACF3UF_002685"
     CDS             2292..2870
                     /locus_tag="ACF3UF_002685"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3672733.1"
                     /translation="MKTKDLIIEEFIKSFGENGFEGTSVDYLAKQVGIKKGSIYTHYS
                     GKNEIFTIACEKILDKCIVAIKQLLEVERDKPLDEQLFILLKTVCLESDFLTADEIAF
                     SKRVAILSSSELLSLVDKLLAKYDNFIDDTVSRIFIDCAKQKMLAEEEITSAISVYRM
                     LLENLYIDSLANQNCNEKLNHLWRYFWKGVCS"
     gene            2902..>3328
                     /locus_tag="ACF3UF_002686"
     CDS             2902..>3328
                     /locus_tag="ACF3UF_002686"
                     /inference="COORDINATES: protein motif:HMM:NF018410.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HFD3672734.1"
                     /translation="MEIIKYIGAAFSTWFIGFFPYFEIYIAIPAGFAAGLNWFDAFLW
                     ASLGNWMVIPFVDICYEWLMKFNFMKKIMEKSLNGKWENRIEKHGAWVILLLTPLAGV
                     WTIGVIAKALKFNRAKLWIYSATSVGITGLIITILIINGI"
BASE COUNT         1290 a          477 c          613 g          948 t
ORIGIN      
        1 agggcaacac caaaacaagc gcatgatatt gttgtcaaaa acttaccgac caatttagaa
       61 acccttcata aaacgggctt atttagcgat ataaggcttt acaatagaga aggagtgaaa
      121 ctctattcaa gcttagaaac gccttccatt agtgcgaaag agaccttaga aagagaatta
      181 aatcgtaaag tatcagggaa agaaattcaa ccgactttgg agagaataga gcaaaaaatg
      241 gttcaaaatc aacaccaaga aacccctgaa tttaaagcaa ttcaacaaaa attggaaagc
      301 ttgcagccac ctataccacc aatacccaaa acacctaaac ttccaggact ttaaacctta
      361 aaaaaggaaa agagtagtta ccaaaaaacg gtaactactc tttttttata aaaacctttc
      421 ctcatgtttg aaaagctgat cgagaaataa agcacacaac ggtattcttt cttttttcag
      481 ttggtacatt ttgcagtctg taacgtgtca tttactgttt gttaccttaa catatccagt
      541 cgaaaacaca agggtatata aacgagcaag ctcgcccttg tgttttcttt gtgtctatgt
      601 tgcgttctcg tcacagcaaa cgacacgaac acactggcga aaatgaacca actgaaaaaa
      661 gaaaggagca tacactgtaa tttatttcta gcttttaaaa catgaggaaa acagcttcac
      721 ttcctcaaac gcctaacaaa aatggttgtc aaaaaactaa aaatcaaaaa aaagaaaaga
      781 ggaaaagaaa atggaaaaaa caaaaaaatt acaattagaa gattttacag aaaatgagtt
      841 ttttggaaca caagaacagc aatatctaaa agctcaagta agagaagagc taaaagagca
      901 aggctttatc atagatagca gttttgaggg cgattttaaa acatggatag gtgtatacgc
      961 aagaccaaaa gataaaccga cctacttaga ccctcaaaac gataaagaag cagaagaaca
     1021 agagcaatat tctattaacg gctttaaaca agattttagc gaatggtttg agtgggaaat
     1081 aaaaaatttg aaaattaaag aaatgtaaaa aaaagccaaa aatcaaaaag aaaaggaatg
     1141 atgaaaatga aatacattaa aaacgttgaa acattagaag aattgaaaaa agcctacaaa
     1201 aagttagctt tgaaattgca ccccgattgt ggtggtagca atgaagaaat ggcgcaacta
     1261 aacaatgaat atgatgaatt gtttgtcaag ctaaaaaaca ctcataagaa caaagacggc
     1321 gaaacctata caaaagaaac gactgaaacg cccgaacaat ttaaggacat tataaatcaa
     1381 cttttcaatc tgaaaatgga cggtgtatca attgaaatcg tgggaacttt tatatggtta
     1441 acaggcaaca caaaacctta taaggacgac ataaaagccc tagaatttcg ttattcacca
     1501 aaaaaatacg catggtataa agcaccaagc gattataaaa aacgtagtcg aaaaaattat
     1561 gatatggaca caataagggg aatgtatgga agtcaaaagg tgaaggaaga taaagaagaa
     1621 aaaaaatact tacaagccaa ttaaggcttg taagtttgtc agaaaggaag ttttaaagtg
     1681 gatattaaaa taaaaaaaat aaagggtatt cggattttat ggtggaaaag ggcctataag
     1741 ttactctttt ccaatttctt aataagtgtg gaaaaatcta caccatagtt gcctgttttg
     1801 tctcggtctg ttatttgata cgaattgaaa ctatcgtata acatagcttt gctgaatgca
     1861 cttgaattaa atcgtggctt cctcttttta tggagctttt cattaaaaat tattttagct
     1921 cgtaaaaacg gaactctttt agaagctttg agagcggaac tacctgcatt tgaacaaacc
     1981 attgtccctg aatttaaagg ggctgttaga gctgttttga aaaagattca tcgtccttct
     2041 ataggggtta aaatgggtga aatagctaat tatagttcca catcaagtcc aatgggacaa
     2101 ctgaagaaaa tgtttgggta acgaaacaca cagaatgagc aattttaata ttaaaattga
     2161 agagttacca tctctagaga aaagtttccg ccaaagtatt gacacataca aatcaccact
     2221 attacttgac aaatggaatc acctagtata aaatactaac taccggtagt tagtattaag
     2281 gatggtgaat tatgaaaaca aaagatttaa ttattgaaga atttataaaa tcctttggtg
     2341 aaaatggatt tgaaggaact tctgttgact atctagcaaa gcaagttggc ataaagaaag
     2401 gttctattta tacccactat agtggaaaaa atgaaatatt tactattgcc tgtgaaaaaa
     2461 tactagataa atgtatcgtt gctataaaac aattgcttga agtagagagg gataaaccat
     2521 tagatgaaca actttttatt ttgcttaaaa ctgtctgtct agaaagtgat tttttaaccg
     2581 ctgatgagat agctttcagc aagcgcgttg caattttatc tagcagtgaa ttgttgtcgc
     2641 ttgtagataa attattagca aaatatgata attttattga cgacacagta tcacgaattt
     2701 ttattgattg tgctaaacaa aaaatgttgg cagaagaaga gataacgtct gccataagtg
     2761 tatatcgtat gttgttggaa aacttatata ttgattcatt agcaaatcaa aattgtaatg
     2821 aaaaattgaa tcatttatgg agatattttt ggaaaggtgt ttgcagttaa aaattaaata
     2881 aacttgattg gaggtttaat tttggaaatt attaagtata ttggagcagc attttcaact
     2941 tggttcatag gtttttttcc ttattttgaa atttatattg caatacctgc aggttttgca
     3001 gccgggctaa attggtttga cgctttttta tgggcttcac taggaaattg gatggttatt
     3061 ccgtttgtgg atatatgcta tgaatggtta atgaaattta atttcatgaa aaaaatcatg
     3121 gaaaaaagtc taaatggaaa atgggagaat cgcatagaaa agcatggtgc atgggttata
     3181 cttttgttaa ctcctttagc aggtgtttgg acaataggtg ttattgctaa agcactaaag
     3241 tttaatcgag caaaactttg gatatatagt gcaactagtg ttgggattac tggattaatt
     3301 attacgatat taattataaa tggaatta
//
LOCUS       DAXLPY010000135         3287 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.140, whole genome shotgun sequence.
ACCESSION   DAXLPY010000135 DAXLPY010000000
VERSION     DAXLPY010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.140"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            198..1823
                     /locus_tag="ACF3UF_002687"
     CDS             198..1823
                     /locus_tag="ACF3UF_002687"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFD3672735.1"
                     /translation="MKKIYSKEIDCFRGIAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
     gene            2455..2808
                     /locus_tag="ACF3UF_002688"
     CDS             2455..2808
                     /locus_tag="ACF3UF_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672736.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
BASE COUNT         1187 a          424 c          578 g         1098 t
ORIGIN      
        1 gtcgcacaaa taattaatcg gatattttat gttcatattt tttgtgatca acgagaactg
       61 atggggcaaa gatacatttt agatactttt aactgttaat ttacaaaaca aggtgaaacg
      121 aatagaaaaa tgaaaaaatc gatacggaag aatatgtttg attaaaacat gcatgaagag
      181 aaggaggttg atgatacatg aaaaaaatat attcaaagga aatcgattgt tttagaggca
      241 ttgctgtttt agcagtgata ttttatcatt tgccaaatag tttgctgcca ggcggattgc
      301 aaggagtaac gatctttttt gtggtttctg gttttttaat ggctaaaaat acgataagag
      361 atgaaaaaaa cagacaattc agttttttac atttttacta taagcgtatc aaacgtattt
      421 atccattttt actgttttct ttggtcgtat tcattttcat actagggatt agcaacattc
      481 gattgatagg aaacattcgt agtgagctac ccagtttgat ttttggctat aacaattggt
      541 ggcagctgaa tcaaggagta tcttattttg actcttactt taatgcttct ttatttaaac
      601 attattggtc gctttcagtt gaactacaat tctatttgat atggccattt ttgtttattg
      661 tcattaagcg tatgagaaga aaacaagtgt tttacttaat ctatacattg atttttgttt
      721 ctattctttt tagtttgttt ttaccttcaa ctaaggcata ttatcatacg atagctaaac
      781 tttttccatt tttattagga gtttgggggt attttaatcg aataactatt ggccgtttct
      841 ttgaacaaaa cacttttagt aaaatctggc ttttattact agctagtctt tgtctgattc
      901 tgttcccgat ttttccttat acactaaatg aactactgat cagtatttgt tttgctctat
      961 tgttagccag tgtcgatgat atgaacattg caaaaaagac caaaatcgct agtacaaaac
     1021 tttcttttgt aggaaaaatc agttatgaac tttatttggt gcatttccca gtattgattg
     1081 ctctgacaaa tctattcaaa catcaccatt ggaaatattt ggatatcgca ggtctattca
     1141 ctgtgttttt atgtacatta ctcatgatta cttgctttag aaaaggagtg caaaagatga
     1201 gatcacccaa aatttggaca gctatggcac taatgataat cggagtttct gtactggtat
     1261 tacgtgctcc tgccagtcga ctgaccgctg accaaaatca gttgcaaagt ttattaaaag
     1321 aaaactctag taaagcaaat gcaggagaaa atctgttgtc acaagagaag aaaatattat
     1381 ttatcggtga ttctgttatg ctgggggcgt atcaggaact aaaggagaca tttaaaaaag
     1441 aagcattggt agatgcaaaa gaatcaagac aaatcactgc gttaccagaa atcttaaagg
     1501 agcataaaga tttagtttct taccaacaaa tagtgatcgg gttaggaacc aatggtgtga
     1561 taacagatga agctatagaa caaacaatgt ctttgctgaa agataaaaaa gtatactggg
     1621 taaatataaa agcaccaact ggctggcaag atacgataaa tgccacatta gctacattgc
     1681 caaatcagta ttctaatata acgatgatcg attggtatag tgagagcaaa aatcatcctg
     1741 aattttttta tgatgatgaa acccatttga atgaaagtgg acgtacagct tatgcaaagt
     1801 atattgcttc agttattcaa taaggtagtg attacgtgtg ttaaccttac tttttcctaa
     1861 taggtgaatc aatttaaata aaaaatactt catatgataa acggtgttta agaggaggag
     1921 ctttttaata ttcgtggtaa aaaagagatg ggcgaggtcg ttaactgaga gcttcttgga
     1981 aagaaatcgc tttggattta tcctctttgt tatacagaac atgagcgaga cgacaatact
     2041 aggatgtatg ttctgatcga agttttatgg ttacaagcag caatcagctt agataaaatt
     2101 aaggatcgta ggaaccaagt aaagaaggct gttagtaaag aaacaaacga tcaagtatgt
     2161 tttactctta agaagatgca gtgaataaat aatagtaata taatgctaga agggactgtg
     2221 acaaaagacg tgtcacagcc ttttttgtta ttttaattat cgtccagtct ttttttataa
     2281 atgattgctt aagcattaaa tattaaaaaa tatagagttc aaaattactg cacaattaga
     2341 tgaaaaattt gaacaacaaa aagtgtattt ttatactata atagcttttg aatttagtta
     2401 ctctattcaa aagttatgct atggacaaga aaaagaataa atagaggtga gaaaatgaat
     2461 agtttcaaga aaaaatttgt gagtagattt ttaaatatga aaaatttttt tgaaaaaaag
     2521 ggagattatg atgcatataa ttatgtatta aatctagaaa agcaaacata ttatacacta
     2581 cgtaaaaacg atgataatga cttttggact atgttaccta aaatgctttc gattgactct
     2641 aagctttccc ttttagagga atttattaat ttagacattg aagaattttg cgggggaaaa
     2701 gagttaatta atatggtaga gagtgattat catacctatt ataaagaaag ttgtggatac
     2761 aaagtggatg agcaatgtcc acaatcaatt attttttaca ttgagtaata tgaactatta
     2821 agcaggaaag caactagaag ctactgattt agtatttaca aatataaact atattgctaa
     2881 caattatttt ctagaaggaa taaaagaact aagaatcaag acgttatctt gattcttagt
     2941 tcttttaaca tggaaaagat ggataatgca ctgttaattc atgatgcatc atcagaaaag
     3001 ttggaaggag aagatagaaa tcattaaatg atttctacag atggtaaatg aaaaaacaaa
     3061 atattagcaa aaatttgcct aaatagatag taacactttc taaattaaat acaagcgcat
     3121 tcataaaatg tttatacaaa tatctatgtg ataaaaattg gatatgttca caataaatag
     3181 gaattaaaat aacgaattta cgtttgtttt tatttaccaa tcaaattatc ttaatgcagg
     3241 aataaaaaat taaattacat attgttaatc atttacatct ccattaa
//
LOCUS       DAXLPY010000136         3023 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.141, whole genome shotgun sequence.
ACCESSION   DAXLPY010000136 DAXLPY010000000
VERSION     DAXLPY010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3023
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.141"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(287..649)
                     /locus_tag="ACF3UF_002689"
     CDS             complement(287..649)
                     /locus_tag="ACF3UF_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672737.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="ACF3UF_002690"
     CDS             complement(723..1103)
                     /locus_tag="ACF3UF_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFD3672738.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1185..2360
                     /locus_tag="ACF3UF_002691"
     CDS             1185..2360
                     /locus_tag="ACF3UF_002691"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFD3672739.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2437..3021)
                     /locus_tag="ACF3UF_002692"
     CDS             complement(2437..3021)
                     /locus_tag="ACF3UF_002692"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3672740.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          942 a          578 c          498 g         1005 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc ttactaggtt
     2401 tcgtcctttt tcataattac tccgtaccat accaaactat tctgaaattt caattgtttc
     2461 aatcactaca tcatgtacag gtcggtcttg tggaccacgt tgtacatttg cgatttcatc
     2521 tactgtgtcc atcccttcta gtacatgtcc aaagactgta tgtcggaaat ctagccaagg
     2581 agttccgcca cctttatacg cttcaatgat ttctgatggg aatccagcac cttctagttg
     2641 tccaagcata ttagctggca catttgtgtt atttacaata aagaattggc ttccgtttgt
     2701 gtttggacct gaatttgcca tagataaagc tccgcgaagg ttgaacagtt cacgactgaa
     2761 ttcatcttca aaactttcgc cataaatact ttcgccaccc attcctgttc cagttggatc
     2821 gccgccttgg atcatgaaat caggaataac gcggtgaaaa atcacgccat cataataacc
     2881 ttttttggaa agttcaatga aattttgaac cgtcttcggt gctagttcag ggaataattg
     2941 aacagtaatg tcaccacggt ttgttttgat aacagctttt ggtccttttt cactttttaa
     3001 atctagttgt gggaatgcca tat
//
LOCUS       DAXLPY010000137         2974 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.142, whole genome shotgun sequence.
ACCESSION   DAXLPY010000137 DAXLPY010000000
VERSION     DAXLPY010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.142"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..214
                     /locus_tag="ACF3UF_002693"
     CDS             <1..214
                     /locus_tag="ACF3UF_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672741.1"
                     /translation="AEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLDELK
                     AIADVLGVKFVQAFILPDGNEIKIGN"
     gene            230..1072
                     /locus_tag="ACF3UF_002694"
     CDS             230..1072
                     /locus_tag="ACF3UF_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672742.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1135..2937
                     /locus_tag="ACF3UF_002695"
     CDS             1135..2937
                     /locus_tag="ACF3UF_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFD3672743.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
BASE COUNT         1086 a          397 c          615 g          876 t
ORIGIN      
        1 ggcagaaatg attaaagaac tgtgtgagca aatgaatata agtgtttccg aacttgctag
       61 acgtattgga cagactccac agaatttcaa taagaaatta caacgagaaa cggtaacctt
      121 agatgagttg aaagcgattg ctgatgtgct aggtgtcaag tttgtgcagg cttttatatt
      181 gcctgatggc aatgaaataa agataggtaa ttaggaggtg taatttgtat tgaaaatcat
      241 aacaataaat gatgttgagt atgctgtatt tgctgctaat gaaggtactt ccaaaccaca
      301 acctcatatc atagaaacga aatctggtac tattccagaa ggaaaacaac tgagtttatt
      361 aaaagaatat cttaagcaga atgatatttc cccaataaaa ggagcaacaa catattggtg
      421 cattgacaag gttcttaagc ttgattcaag taaagaaaaa actataagtg aaacaatcca
      481 taaacaaaaa tacttatctt taactgaaga aaatattgag aaacagcata agtttgtagg
      541 tgcaagctct aattatggga aagaaggtct aataatacat gatgttttga atgcatttcc
      601 tcttcataat gatttaaata ctattgcgat gaagattgcg gtaattgatg taacaaattc
      661 aacacatctt tctcaatata agagcaggtt gtctctatat gatttggcta aagtaattct
      721 ggagattcca aattttgatg atcggttggc aaaaggagat cctcagttga taaatattat
      781 cgcaaggaac attggtgcag ttaatatgtt ctcatttgca tccaagtact gtacatatca
      841 taatgtggaa gtgtgtggga gagatgatta ctccatcttt gatggtatcg ttaaaaatac
      901 tcttccacac tatatccaag gactaactac gaataagatt gatacgtggc gaagaagttt
      961 tgattacgag gcatttaacg aatgtgttgg aaaactactt gatgaaaata atatacatat
     1021 tccttttaga agaagaaagt tagatcactt cttgtggtat gcgaataggt agaatataag
     1081 aaaaaggcat cgtaaaagtg attctggata aaattaatgg gggaggaaat aatagtggga
     1141 ttatttgatt ttctaaagaa aaaacaagga aaggttagta aacacgttga ttatcaactg
     1201 gcttctagtc tatttcgtac tggtaaagtt tttgctgaaa aattggaagt ggacatatca
     1261 aatgtagatg agtttcgtaa aacttttatc gcttttgatg tggaaacaac tggcctaaat
     1321 tcttcttcag atagaattgt agagattggt gcggtgctat ttaaagaagg agttccaatt
     1381 caatcattcg gaactcttgt caatccaaaa gttagaattg cagcctcagc ttcggcaata
     1441 aataatataa ctaatgaaat gctaaactct gctccaaatg agcaggaagt ttacccccag
     1501 ttggtagaat ttttaggaga tgcactagat ggaaaaatca ctatgtgtgc acacaatgca
     1561 agtttcgatt ttggattttt aagtaacaca ttttctagac ttgggtatga tgctaaaatt
     1621 aagtatgttg atactctgag tctctctaga aaacatataa aaggcattgt aaatcataag
     1681 caagagactg tagcggaata tttcggatta ataaatgaca ctgcccatag agcggaatca
     1741 gatgcagata tatgcggaaa gattttttgg ggtgttttag atattattga ggagtcgttg
     1801 gaagaacaaa aaaagcaaat agaaaagatg actccagaca taaaagaact tgaagcttgt
     1861 gcttttattc aagatattat tgagaaaaaa ggatgcgaca ccagttggat caggtatcga
     1921 aaaaacagta ataattatgt cgatgtaact tgtctatata cattcttaaa gtttaagttt
     1981 gctaagaagg gaaattacat cattattaga aaagatgcta caaatggaat tgatttacct
     2041 atagaacctt gtactgtaag tgaaggcggt acaacaaatg tgcgagtcta ttttcgtagc
     2101 ccctttgact taacgcctct ttcaaattat attttcagtg cttatagcga ttgttataat
     2161 tctatgaatg aatatatgag tgttagtaat tacactaaaa aagaagcaga gcaaagcctt
     2221 agtatgctga aatctatttc aaaatcagcg atgaaagagt tattattcga tgcaaaaaat
     2281 cgtggatatg atgagactga agttaaccta aatattgaaa aagtgatatc tagagaagat
     2341 gtaattatta acgggttgca taatcgagtt tcattaaaca agatacgaaa tatagggaat
     2401 tgggagaaag gatttgatgc aggttatcca tattgggaac gtggagaaac tgctaggaaa
     2461 aatggcaaag tagatgaagc tattgcactt tttgataaag ctcgatataa cggctatgat
     2521 gctcctgcgc tatatgattc ttatgctaaa gcttatcgaa aaattaagga ttacgataat
     2581 gaaattctca ttcttgatga aggaattatg cgtaaaacac ggcacgatgt tggtacttta
     2641 gaggctcgta gggataaggc aattaagcta ttatttgcta aacaagaggc agagcggata
     2701 gctaaggaaa aatctgattt tctaaaagcg aacaaaaaag aggatgcgat tagtgagcct
     2761 agcaagaagc gtggaagaca gattattcaa atgactgatg atggaacaat aataaaagaa
     2821 ttcgatacta tagcttctgc tgtaaaagaa gttggcgtta actcaaaaag tattagggat
     2881 gctgcaaatg gagttcaaaa acatgctgga ggatactact ggaaatacaa agattagcag
     2941 ataatctaag ataacctagg atcttcttaa taga
//
LOCUS       DAXLPY010000138         2833 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.143, whole genome shotgun sequence.
ACCESSION   DAXLPY010000138 DAXLPY010000000
VERSION     DAXLPY010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.143"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..1347)
                     /locus_tag="ACF3UF_002696"
     CDS             complement(<1..1347)
                     /locus_tag="ACF3UF_002696"
                     /inference="COORDINATES: protein motif:HMM:NF021909.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFD3672744.1"
                     /translation="MVGKNNKKLLELKSNPIIKKWRISRLKTGVASIVIFSGVLLSST
                     IFIPLHTVSAEETVTTTYYDQSKNVSDQLTNINISISNNKEKVIFPHNAESLTSNYAF
                     KVPDSVNPKDYFYIDLSENANFYGVTEANSVTMPNLLAPDNSIIATGKYDIDTNRIQY
                     EFTDYVAVHDNVSGKISLPIFIDPEVVTNTSYQTITASIGNSKKDLSLLVDYSKNVGP
                     QYNANGAGNIFNVDLNNHNFSHTIYVNSLKQTLGNKSIEIRNQRKEENGYNSEIIYDK
                     TNTQIKVYKVKSNGRLTDSFSIATNDSLEDVTNQCYIDFYDNKINISFPSNIDNETYV
                     VQYTSPYTDKKDIATRVVMYGYSPYQLGNTSWYWDNYVKLTDGNASGDGSVISPDPET
                     PVTPETPDPETPVTPETPDPETPVTPETPDPETPVTPETPDPETPVTPETPDPETPV"
     gene            1676..>2833
                     /locus_tag="ACF3UF_002697"
     CDS             1676..>2833
                     /locus_tag="ACF3UF_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HFD3672745.1"
                     /translation="MNVFDATLKRLEYIFEEFDKVYFSFSGGKDSGIMVQLANLVAEK
                     LDRNFDLLILNIEANYTATVDFIKKIEQLPRVKNIYHFCLPFFEDNNTSFFQPQWKMW
                     DPSEKEKWIHSLPKNAITLENIDDGLKKYYSLSNGNPDRFLRYFQNWYKEQYPQSAVS
                     CGVGIRAQESLHRHSAVTKGENKYKNRCWINITLEGNILFYPLFDWKVDDIWAATFKC
                     GLEYNYIYEKMYKIGYKYRDMRICQPFGLQQRKALNQFAELEPETWDKLVKRVSGVNF
                     GNIYGKTSLLGLNTSQKPSFMTWQRYSIFLLETLGLYSPLLMNHYYRKICILFAYYKN
                     KYNMDIQDMPDESKRKDWIKDERLWNDWKGIAKALEKNDFVLSTRNYSLTKK"
BASE COUNT          978 a          364 c          458 g         1033 t
ORIGIN      
        1 tactggagtt tctggatctg gagtctctgg cgttactgga gtttctggat ctggagtctc
       61 aggcgttacc ggagtttctg gatctggagt ctcaggcgtt actggagttt ctggatctgg
      121 agtctctggt gttactggag tttctggatc tggagtctct ggcgttactg gagtttctgg
      181 atcaggtgat atcacactac cgtcaccact tgcatttcca tctgttagtt ttacataatt
      241 atcccagtac cagctagtat tgcctaattg ataaggagag taaccataca taactactct
      301 agtagcaata tcttttttat ctgtataagg agaagtatat tgaacgacat aagtttcgtt
      361 atcaatattg ctcggaaaac taatattaat tttattatca taaaaatcaa tatagcattg
      421 attagtcacg tcttctagtg aatcatttgt agcaatagaa aaactgtcgg ttagtcttcc
      481 gtttgatttt actttataaa cttttatttg agtatttgtc ttatcgtaga taatttcaga
      541 attatatcca ttttcttctt ttctttgatt tctaatttca atacttttat ttcctaaagt
      601 ttgttttaaa gaattgacat agatagtatg agaaaaatta tggttattca agtctacatt
      661 aaatatgtta ccagcaccat tagcattata ttgaggtcct acatttttag aataatccac
      721 taacagactc aaatcttttt tactattgcc tatactcgca gtaatagttt gataagaagt
      781 attagttact acttctggat caataaagat cggtaaagaa atttttccac taacattatc
      841 atgcactgct acataatccg taaattcgta ttgaatacga ttagtatcaa tatcgtattt
      901 tccagttgct ataattgaat tatctggagc taagagatta ggcattgtga cagagttagc
      961 ttctgtaact ccataaaaat tagcattttc actcaagtca atataaaaat aatcttttgg
     1021 attaactgag tcagggactt tgaatgcata atttgaagtt agcgattctg cattatgtgg
     1081 aaatatgact ttctctttat tattagatat tgaaatatta atatttgtta attgatcact
     1141 aacattttta gattggtcat aataagtagt agttactgtt tcttctgctg aaacagtatg
     1201 taaaggtata aaaatagtag aacttaataa taccccgcta aatatgacaa ttgatgcaac
     1261 tcctgttttc agtcgactaa ttctccactt tttgataatt ggattgcttt ttaattctaa
     1321 taacttttta ttgttttttc caaccataaa attatccttt ctacataatt tattcgaacg
     1381 ataaaaatga tcgttcattt tcattataat aatatttaat ggaaaaacaa gttaaaaata
     1441 ttgtttgaat aataattcca attatttcta taatatttgt taactgtaag atactactag
     1501 actaaaatcc atttttgttt ttttaagtaa gtatagtata taaattaaag gtgttcctta
     1561 cattattcta tatgatttga atactataag aaacaacaat tgataaaatt attgacaaag
     1621 tttttaaagg tattaccatt gatattgaac gcttattttt ttagggggat gagaaatgaa
     1681 tgtctttgat gctactttaa agagattaga atacatattt gaagaatttg acaaggtgta
     1741 tttttcattt agtggtggta aggatagtgg gataatggtt cagttagcta atctagttgc
     1801 agaaaaatta gatagaaatt ttgatctatt aatattaaat attgaagcaa attacacagc
     1861 aactgttgat tttataaaaa aaattgaaca gttacctaga gtaaaaaata tttatcattt
     1921 ttgcttacct ttttttgagg ataacaacac tagttttttt caacctcaat ggaaaatgtg
     1981 ggatccaagc gaaaaagaaa aatggattca ttctcttcct aaaaatgcca taactttgga
     2041 aaatattgat gacggtttaa agaaatatta ttcattatca aatggtaatc ccgacagatt
     2101 tcttcgttat tttcaaaatt ggtataaaga acaatatccc caaagtgctg tatcatgtgg
     2161 tgtaggtata agagcacaag aaagtttaca tagacatagt gctgttacaa aaggtgaaaa
     2221 taaatataag aatcgatgtt ggataaatat aactttagaa ggaaatattt tgttttatcc
     2281 tttatttgat tggaaagttg atgacatttg ggctgcaact tttaaatgtg gactagaata
     2341 taattatatc tatgagaaaa tgtataagat tggatataag taccgggaca tgagaatatg
     2401 tcagcctttc ggattacaac aaagaaaagc gttaaatcaa tttgctgaac ttgaacctga
     2461 aacatgggat aaattagtaa aaagagtaag tggagttaat tttggaaata tatatggtaa
     2521 aactagtctt ttaggattaa atacttctca aaaaccttca tttatgactt ggcaaagata
     2581 ttctattttt ttactagaaa cattaggatt atattctcct cttttaatga atcattatta
     2641 cagaaagata tgtattcttt ttgcttatta caagaataaa tataatatgg atatccaaga
     2701 tatgccagat gaatcaaaaa gaaaagattg gataaaagat gaaagacttt ggaatgactg
     2761 gaaagggata gctaaagctt tagaaaaaaa tgactttgtt ttatctacta gaaattatag
     2821 tttaacgaaa aaa
//
LOCUS       DAXLPY010000139         2804 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.144, whole genome shotgun sequence.
ACCESSION   DAXLPY010000139 DAXLPY010000000
VERSION     DAXLPY010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.144"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..693
                     /locus_tag="ACF3UF_002698"
     CDS             <1..693
                     /locus_tag="ACF3UF_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFD3672746.1"
                     /translation="TTLREMKVTKETLTTVLNEIFSTPTKEGIQFEIQGMKETREADY
                     YPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTIPLESYPTEQII
                     AEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTRRGKTDPLKIYY
                     EKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVIHVEEKERKLAY
                     QRHQQMNREMER"
     gene            696..1181
                     /gene="ssb"
                     /locus_tag="ACF3UF_002699"
                     /pseudo
     CDS             696..1181
                     /gene="ssb"
                     /locus_tag="ACF3UF_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            1226..1459
                     /locus_tag="ACF3UF_002700"
     CDS             1226..1459
                     /locus_tag="ACF3UF_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672747.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(1618..1740)
                     /locus_tag="ACF3UF_002701"
     CDS             complement(1618..1740)
                     /locus_tag="ACF3UF_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFD3672748.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            1895..2154
                     /locus_tag="ACF3UF_002702"
                     /pseudo
     CDS             1895..2154
                     /locus_tag="ACF3UF_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328871.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2602..>2804
                     /locus_tag="ACF3UF_002703"
     CDS             2602..>2804
                     /locus_tag="ACF3UF_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFD3672749.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT          973 a          510 c          568 g          753 t
ORIGIN      
        1 acgactttac gggaaatgaa agtaaccaaa gaaacattaa caacggttct aaacgaaatt
       61 ttttcaacgc cgacgaaaga aggcattcaa tttgagattc aaggaatgaa agaaacgaga
      121 gaagccgatt actatccagg atttagctta cgtgtgctgg cacatttgga aaacatgcgg
      181 ccagatttta aggtagatgt gactacaggt gactcgatct atcctgcaac gatcactcac
      241 agtcataaat tgatgtttga ggatcgaacg attcctttgg aatcctatcc tacagaacaa
      301 attattgctg aaaaattaag tgcaaccttt gattttttaa cagataattc gagaggaaaa
      361 gatttttatg atctctatac tattcctaaa atggagaaga tcgatgagaa gaccttgaaa
      421 gatagtgtga gaaatacatt tacacgtcga ggaaaaactg atccgttaaa gatatactat
      481 gaaaaggata tggatgtact gaaaaatagt cacgagctaa aagatacctg gaagaaatat
      541 caaaaaagca atccttatgc tgcgtcgatc acgtacgatg agacaatgga ttcgattagt
      601 aatttgatgg aaaaagtgat tcacgtcgaa gaaaaagagc gaaaactagc ttatcaaaga
      661 caccaacaga tgaatagaga aatggagaga taaagatgat taataatgtg acattagtag
      721 gacgcttaac caaagatcct gatttacgtt ataccgcaag tggtactgca gtagcgactt
      781 ttaccctagc cgtcaaccga aatttcacga atcaaaacgg caattgagaa gccgatttta
      841 ttaactgcgt gatttggcgc aaaccagcag aaacaatggc gacattagct aaaaaaggta
      901 gcttgattgg tgtagttggg cggattcaaa cgcggactta cgacaaccag caaggacaac
      961 gtgtatatgt gactgaagtt gtagcagata actttcaact attagaaagt aaagcagcga
     1021 cagagagccg tgcgcacgct gatcaatcgt ccaccagtcc aagcaccgcc acctttgaac
     1081 aacggaatac agcgacgcct aacaacaatg gattgaacgc ttcacagaat ccatttggtg
     1141 gacaatcaat cgatattagc gatgatgatc taccgtttta gtttgagaaa gaaggagtaa
     1201 gcatggcaaa aaaattagtc tgacgatgga tctattgata cccgtaattg catttataga
     1261 cgggatttct ttgggcgtca ctgaaaatcc tttggtaaat agaattgcga aaggatcact
     1321 atttcttgta ttcgtgtatc ttgtctgttc ttatctttta aaaagagcag gaaaggataa
     1381 ttccttttgg cgattgacta aagtcacagt agcagcgaca gctgttatac ttacggctat
     1441 tctaccgctt tatatgtaga gttaacggga aatcgttgaa cttcttgcga aatattgcta
     1501 taatgaacat gaaaaagagg agttgcgcta acaacccctc attaacagca ccgattaaag
     1561 aacggtggca gaatattagt tatttggaaa taaccgctga cctgctaaag tagacggtta
     1621 tttctttttg tcatttttaa gcatatttac aatcaaacta atcaaagcaa tggtaaacat
     1681 accaaaacca agaatggttt gaattgtctc atatgcggac aaaaggctta ctcctttcat
     1741 agattttagc acttacattc ataagcacca ccacctttcc agaagtcgcc accgtcttca
     1801 aactttactg tcttgactat tatagcatat ctaaaatcga ataaaaattc tcaattttag
     1861 ctgtttttgc tataatttta gcgaggtgat cgtgatggaa caatatattg gtttactcga
     1921 taaattaggg tgatcaagac acagccattg cttgtgcgat ttacattacg cacgagtcat
     1981 gaaccaatca attgtgtagt ggccaatata gaaatagcgg ataaattgct gattttggaa
     2041 gaaggcaagt atactatttc agtgacaggt cacttcaata aacgaaatca actagtcatt
     2101 gaatcaatgc aaattagaaa ccctgatcat tttacgagat taatgggcat ataaataaaa
     2161 gaagagctgc agtcctaaat gaggattgca gctctttttg ttttacatag aaacaagaaa
     2221 aatgaaaagg cctttttagg aaggcgcaag cgccttctca attgaaaaac ctctctctca
     2281 ctccaaccgc caccgccgtt cgagaagaaa ggaagtgaac gttgcacgtt cactaagata
     2341 aggggtcttg caaagcaaga caaaatagaa aaaacttcct ctcaccaaaa ggttcgttcc
     2401 tgttcgctat ctctttattg atttgccaga ccggcaacaa gttgcctttt atcaccaaaa
     2461 agcgacaagg acaagggtaa atggcacgct gcacgccctt gtccttgtcg cttttagttg
     2521 attcattctg gccaacaaat caataaagaa agaactaacg aaaggaagta aaacctttcc
     2581 taagaggagg cagaatcaat catgcgaaag aaatttgatt attggggtgt tcccttcagc
     2641 gaattattcc caaactatca tgcaccatat actgtcgaat gcgattgtgg agaaagagcg
     2701 aaatgtatca aaagctattg tttgtatcaa tgtccaacat gcgggaaaaa atataccttg
     2761 tcttatggcg attatatttt gattgatgag aaaggaaaga aacg
//
LOCUS       DAXLPY010000140         2695 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.145, whole genome shotgun sequence.
ACCESSION   DAXLPY010000140 DAXLPY010000000
VERSION     DAXLPY010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.145"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..681
                     /locus_tag="ACF3UF_002704"
     CDS             <1..681
                     /locus_tag="ACF3UF_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672750.1"
                     /translation="VVVYGVAYYLLSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQ
                     FIRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMY
                     LFEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHT
                     SIHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKP
                     YVLGKVVI"
     gene            725..994
                     /locus_tag="ACF3UF_002705"
     CDS             725..994
                     /locus_tag="ACF3UF_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672751.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1226..1522
                     /locus_tag="ACF3UF_002706"
     CDS             1226..1522
                     /locus_tag="ACF3UF_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672752.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1524..1946
                     /locus_tag="ACF3UF_002707"
     CDS             1524..1946
                     /locus_tag="ACF3UF_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672753.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1965..>2695
                     /gene="mobL"
                     /locus_tag="ACF3UF_002708"
     CDS             1965..>2695
                     /gene="mobL"
                     /locus_tag="ACF3UF_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HFD3672754.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNT"
BASE COUNT         1032 a          377 c          524 g          762 t
ORIGIN      
        1 gtggtggtct atggggtggc ctattacttg ttaagtgagc caaaacagat cgcggcgtca
       61 aatattttca cggcagtaat gacattaatg tgtgtcatgt gcttttctat ttttagttac
      121 ttactcgtcc aatttatcag gcaaaattta acaatgagta aacttttcaa aagtttattg
      181 gacttactta tcttaggcag tatgttaacg actctaacag atcggttcga acaatctgaa
      241 aaaacggtag aggggataaa gaacttctta acgacgattg atcaatttat aaatggatat
      301 atgtatttgt ttgaagtagg ctttattctc actttgtttg gttgtgtatt tataaaactc
      361 attaaaagat caatcgaaaa agaaatggtt attgatctaa ttccgacgct gagcggctat
      421 gagtattacg ttgattttgg aaagtatgag gagttgatcc atacggatat cgttcacacg
      481 agtatccatg aagtaaccgt taagggcatc agatctactt taaaagatgg acaggagacg
      541 aaaacaatcg accgaagaaa agaggtctac aatttttata aagttgaagc aagtctacga
      601 tatggcattg ggaaattgag gttagatggg agtaatattc aacaaaacaa accatatgtt
      661 ttaggaaaag tggtgattta gaacttccta tgaaagatga ataaataagg agaatctttt
      721 gaaaatgatt cttctttaca gaattgtgct tatagttggc acggagttaa aaatcttaaa
      781 gaaggagcag ttattcaaag tgaaagaaca tcataatcag ttactatgta ttaaaacggg
      841 tacgatgaac attcaatacc gaacagaata tttagaatta acgaatcaaa ctgatttttt
      901 gtcgattcga gagcaacata agcaagaaaa attaatggct acttatagcc aattgattga
      961 tgagtgggaa caattcaagg aatctaaaac ataaaattcc atttaaacac cttatttttt
     1021 aaagagcata aggaaacgtg accccacttt taaaaaaagt ggttggatag gctgtgccta
     1081 tcacgtttct gaaaaaaata aatgacccca aaataccaat atataggata gtacaaggat
     1141 agcaaaggat agtaaaagga tagaggtagg atagcgaaaa ggataggatc cttttcacta
     1201 tcctatatta tattggagga tatttatgaa tgttaaaatt agagatttag atccaaaatt
     1261 catttctgaa attgatcgaa gatgcgttga actaagtaat cgtacaggaa ataaatggag
     1321 tcgtaatgat tatttaaagc tactcgttga aaatgatttt gatcgtcctt tgatggaata
     1381 caaacaagaa aagtttgacc agttattaga aaagttttca gaaattcaaa gttataacac
     1441 aaagatatta gaagaatatg ttagccaaaa taatcgtatt atagaaatct tgattgagca
     1501 aaatagagga agtgaacttt gatatggcaa aggttataga caaacacatt tactttcacc
     1561 aaacacatat cgatgtattg gatgaaacta tttctactca tgcagaggtt aaaaactata
     1621 gtgaagctgt tcgcttttta tgtatgaact atgatccaga agtggagaaa aaagtaaatt
     1681 ccaatcaagc aaagttgaat ggaatgagta aagaaatttc tattttaacc gaaatggttt
     1741 cagaatttgc ggatcttcat ttgaaagata caggaatatt aattggtaaa aattcaactg
     1801 tttatcaaga agcaaaagaa cgagtggaag gaaaaattaa atccaatcaa acaaaaaaat
     1861 attcccctca gttgaagaaa cctgtgaatg aatctgttca tgccagagta gatccatttg
     1921 atccaacgaa gattctaaaa agataaaaat gaaggaggat aataatgact caatcgcctt
     1981 cagttattct cacttgtcaa tttactttgc cgaataaaaa gtcattttct acttatattg
     2041 actatattac aagggaacag gctcttgaag aaaaggaacg acgtacgccc gaagaagaac
     2101 aggaacttca acgaatcaag aatgctttag aggagtttta tattcctgaa ggagaaactt
     2161 tttcggagag taagacgggt aaagaattca gtgaaacgtc gaatgaagct caatcgttga
     2221 tggaacatgg aatcaatttt gacaagttag aggaacaaga ttttaccaat tatctttctt
     2281 atatgacacg tcactatgcg ttagaacaaa agaaagaact gacgcaaagt gaacaaaaag
     2341 aataccaacg cttgaaccaa gcaatgaaaa aatatcaaac agaaccccat aaaaaagctt
     2401 caggaaatct tcctggagtt ttttctatag cttcagacga agtgaaagga agtgatctga
     2461 aggagattaa gcaaatcttc caaagaggac aacaaaaagg ctcaatcatt tatcaagatg
     2521 ttgtttctca tgataattcg tatcttgaaa aaataggatt gtacgatccc aaaacagata
     2581 ctttagatga agaagggtta aaagcagctg gaagaaaaat gatggagaca ttattcgaga
     2641 aagaacaatt gaatgaaaca ggttactgga tggcaacgat tcaccgtaac actaa
//
LOCUS       DAXLPY010000141         2669 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.146, whole genome shotgun sequence.
ACCESSION   DAXLPY010000141 DAXLPY010000000
VERSION     DAXLPY010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.146"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..287)
                     /locus_tag="ACF3UF_002709"
     CDS             complement(<1..287)
                     /locus_tag="ACF3UF_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3672755.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGT"
     gene            complement(498..2045)
                     /locus_tag="ACF3UF_002710"
     CDS             complement(498..2045)
                     /locus_tag="ACF3UF_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFD3672756.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(2147..2500)
                     /gene="tnpB"
                     /locus_tag="ACF3UF_002711"
     CDS             complement(2147..2500)
                     /gene="tnpB"
                     /locus_tag="ACF3UF_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFD3672757.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2490..>2669)
                     /locus_tag="ACF3UF_002712"
     CDS             complement(2490..>2669)
                     /locus_tag="ACF3UF_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672758.1"
                     /translation="EIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIYNGINN
                     YILQAILKELLSNAL"
BASE COUNT          769 a          542 c          455 g          903 t
ORIGIN      
        1 gttcccatag atacacattc ttttactttt attggaaaag taaaatcaat atcagctttt
       61 tgctctacat atgcaatctt taccagtttt ttattgatat cttcattatt aatggagacc
      121 tctccctgat gagggataat atttaacatt gctttaagta atgtagattt tccagcacca
      181 tttggaccaa taatacctgt tagagcacct tcttgtattt ttaaagaaat ctcgttcaat
      241 gctaaaaaat cgttataaca aacattaagc tttttcactt ctaacataac tttctccttc
      301 taaatgataa tgattatcac gattatatgg tatacagaaa atatatttta gtcaagccta
      361 aattttaaaa tttggatttt tttctgttgc tgaagattag gatgacaaaa ctatttgaaa
      421 cgtaagcgcc ccatagaaca gtacctgtac gtcaaataac ccgacctata gaatagaatc
      481 gggaatgttt ggcgttttta gttacgagaa aaatgttgtt gtacatcctt gttccaaggc
      541 aacagttgat ctaaagtttc tgctgaaagt acgggaagat ttggtatctt atcaaataga
      601 aactctagat actttacagg attcaatccg ttaagttctg ctgttttata tacactcaga
      661 atgattcctg aagttcgtgc tccttcaaga cttgtggaat gcaaccaatt tttccgtcct
      721 atcaccagct ctttgatatt tcgctccgca cgattatttg tgagttctaa acgaccatct
      781 tcaaaaatag gttcaaaacc acttcgtagt ttacacgcat attgaacggc tgcatccaac
      841 ttggattttg caacaggatc tatcgttgcc atccactcat aaaaagcaat aaataatgga
      901 cgcagttctt gttgccgaca gcttaatcgc ttctcaggag aaaagtcttt ccatttcttt
      961 tctaggacaa accatttatc caattgtttg actgcttgag ctgcgggaat atccgtgttt
     1021 ttctttcctt ttggaattgc ttcgaaaaat ttccgccgaa catgcgcgaa acaatagaca
     1081 agtcgtacac tttccacggc attatacccg ctatagccgt cacagtgtaa ataccctgta
     1141 aactccttga gaaaagtttt cggaacatct ccagcacgac tttcgtcgtg gtgataataa
     1201 acgatgggat gctgactgtc ttttcctgta caaaactgcc agtaataggt atctgttttg
     1261 gcactttcaa tcacacgata acttgtttca tccccgtgta gaatctcttc ttgattaaga
     1321 tagactctta atcgttctcc taaagggtct aacgcgtttt gcactgcttt aatatgccaa
     1381 ttggtgatat tatctctcga aatatccaac ccatgtgttt gtttccaata gttctcttgc
     1441 cgataggcag gaactttctg accaaatttc atccggatcg tttccgccac taaactattg
     1501 gaacctaagc tattagaaat caaaggttta ggaacgatcg cttttttaaa agaagaaagt
     1561 ccttcttttt cgcagctttt acaacaatag gtatgttgat aatgggtgag acaatccaac
     1621 atagcctgat ggaaacgaat ttcttctcgt acttttgtcc gtccgatatc tttcatctgt
     1681 gaaccgcaat gttcacaaaa ttgttcttcc aaaggaagga gatgttcttt ctctgttata
     1741 ggtaagtgtt tgattttgtc tgctttcgtt cctacaactc gttgatgtcc ttttactgga
     1801 ataatggtgg cagctgcttc tggaacactt acagaaattt cttcatcact aaaaagattc
     1861 aattgcccat tcgtttcctc aaagagagtc tctttagagc gtccaaataa tttgttggtt
     1921 aaataattga ccttttcatt caatagttgg atttcagttg taagattctg aatggtttgt
     1981 tgttgtgctt gattggtttt atgggcttct tgaagcaact gaagcaacgt atctgtagtt
     2041 tccaaaattt ttcaccacct tgaatcgaac tgattttgtt acagaatacc acaagaaacg
     2101 cacaagaaat aggggttcaa cacatttttt gtgttaaccc cccagcttaa aaaactcctt
     2161 tttttcctgg caaaatagct cgaggttgat cgatacttaa tccttctaac aaccatcgaa
     2221 cctgttggtt cgttaaggtt cgaacttcgt ctttcgtccg aggccatttt aacttgccgt
     2281 tttctatccg cttataacag agaagaaaac catcaccgtc ccaatagaga agtttgaaac
     2341 ggtcttgacg gttcccgcaa aataaaaaaa cggcatcttc gtaaagctcg agttgatact
     2401 cttgttgaat aagactggca agaccatcaa ttccttttcg caaatctgtt tttccgcaca
     2461 caatataaat atgtttggtt tgaagtaaat cataaagcat tggacaacag ttctttcaaa
     2521 atagcttgaa gaatataatt gttaataccg ttatagatca aaacttcaga accattctct
     2581 cttttgatgc gcatcgctaa cttggcagcc gcgggtttac ctttttctgg tgcactcttt
     2641 tcgtttccta attggacagg aacaatctc
//
LOCUS       DAXLPY010000142         2663 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.147, whole genome shotgun sequence.
ACCESSION   DAXLPY010000142 DAXLPY010000000
VERSION     DAXLPY010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.147"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            2..793
                     /locus_tag="ACF3UF_002713"
     CDS             2..793
                     /locus_tag="ACF3UF_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFD3672759.1"
                     /translation="MPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFDGFSP
                     FPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYFGSIL
                     GINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISFVLSM
                     IGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILLQLSF
                     IGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            863..1603
                     /locus_tag="ACF3UF_002714"
     CDS             863..1603
                     /locus_tag="ACF3UF_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3672760.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            1614..2618
                     /locus_tag="ACF3UF_002715"
     CDS             1614..2618
                     /locus_tag="ACF3UF_002715"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFD3672761.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
BASE COUNT          839 a          438 c          544 g          842 t
ORIGIN      
        1 aatacctatt tctgaatatc ggaaaaaagc acgagtttct ttggaaaatc aatggggaat
       61 caatacttgg cttgttttct tatctataat atttacgagc gtcatccaga acttttttga
      121 cggtttcagt ccttttccgg aagaaagcat gcagcagcac ttattgagtt ttctagtcga
      181 taatttactt ttattcgcat tcaactatgc attgttttac attgcgctag tagttgtacg
      241 gggtggcaga ccaaaaagta accttttatt ttcagttttc caaagaaagt attttggttc
      301 gatacttggc atcaatttga tcaattcagt catcaactgg ctactcaaca gtttaatctt
      361 tctgcccatg tttttaatca gcggagtgag tacttatatg cagctgcttt tcagttcaaa
      421 tgcggtacct acgggtgtca tgccagaaga ttttcttgat atcagctttg ttttatcgat
      481 gatagggatg atttttgttt cagcactcat catgagtatt gttggcggtt tattccaatt
      541 tgctgcatgg acaaagttcg actatcctga tttgtcggtt attcaatgtt tgaaatatgg
      601 ctggttttta ttgaaagata gaattggtac gtatattttg ttgcagctgt cttttatcgg
      661 ctggtatttg ctaggagcaa tcgctttgtt catcggtctt ttgtgggtca ttgtttatgt
      721 gaatgtgtca gttgcagaat tttatgaaca agcacggatt gaaaaaggag gtccagacgc
      781 ctattttact tagcatgtaa gcagtttatt catcaaaaaa ataacttttg tggtaggata
      841 aatctttgag ggggaatgta cgatgaaatt aactgtttta ggatgcttag gagcgtatcc
      901 ttataaaaat caagggacaa caggttattt gcttcaatct gacgggttca atttgttgat
      961 cgatgcaggt agtgctacgc tgatcaaatt acaagaacac cttgatccac ttgatctaga
     1021 tgctgtgatc cttagccatt atcatcatga tcatattgct gaccttggtg tattacagta
     1081 ttactggcaa cttcatccta agagaaatcc ggagacattg ctttcaattt atggacacac
     1141 aaaagattcc attcactttg aagaattgac gttggaaaat gtctcaaaag gacatcctta
     1201 ttttgaagct gaagaattaa aaattggtcc ttttctgatt acttttatgg aaacaatcca
     1261 tccagtagta tgttacgcca tgcgtatcgt agaagaaaca acggggaaag tattcgtatt
     1321 tacaggtgat tcaggttatt tggaaagttt cgctgatttt gcgaaagatg ctgatttgtt
     1381 tctagcagat acctatcttt ttgaaggaaa tgaacatcat catgcccatt tcacttcaaa
     1441 agaagctgga gaacttgcga aatcagctaa cgtaaagaaa cttgtactta cacacctacc
     1501 tcagtttggt gatttagaac aattgaaaaa tgaagcgcaa aaggcagcag gcaaagggat
     1561 tgatatagaa cttgctgcag ttgacaaagt gtttaacatt taggaggaag aacatgattt
     1621 ttgtaccaaa tgaaaaccac gacccaagaa tcaatttagc aattgaacaa tatttgctgc
     1681 aagaaatgcc tttagatgaa cctattttgc tcttttatat caatgaacct tcaatcatca
     1741 tcggcagaaa ccaaaatacg cttgaagaaa tcaatcgaga ttatgtggaa gaaaatggca
     1801 ttcatgttgt ccgtcgctta agtggaggcg gagctgtcta ccatgatttt ggaaacctga
     1861 actttagttt tatcatgcct gatgatgggg attcattccg tgactttgcg aaagtaacac
     1921 agccaatcat ccaagcactt catgaattgg gtgttgctgg ggcggaattg aaaggccgaa
     1981 atgatctagt cattgatggc atgaaatttt ctggcaacgc gatgtatgct accaacggtc
     2041 ggatgtttgc tcatggaaca attatgttcg actctgatat caatgaagta gtcaatgcat
     2101 taaaagtaaa aaaagacaaa atcgaatcaa aaggaatcaa atcgatccgt tctcgtgtaa
     2161 cgaatatcaa accatttctt ccagaagaaa agcaaaaaat gacaacagaa gaatttcgtc
     2221 aagaaatctt gttgaaaatt ttcggcgtag agtcagtaga agaagtaaaa acgtacgaat
     2281 tgactgatga agattggaaa aaaatcaatc gaatctctga ggaatattat cgaaattggg
     2341 attggaatta cgggaagtct ccagatttca atttctctcg ccaaaaacgt ttttctatcg
     2401 gttcgattga agtccatttg aatgtctcag aaggaatgat caaagaagca aaaatctttg
     2461 gcgatttctt cggactagga gatatctctg acgtggaaaa aaaattggtt ggacagaaat
     2521 atgataaagc atctctatca aaaatagtca gccaaattga tgtgaagaaa tattttggtg
     2581 cgatagaacc agaagaattg cttaccttac tttattgaaa ataaaaaata gcggaatcca
     2641 catatatgga ttccgctatt ttt
//
LOCUS       DAXLPY010000143         2605 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.149, whole genome shotgun sequence.
ACCESSION   DAXLPY010000143 DAXLPY010000000
VERSION     DAXLPY010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.149"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..493
                     /locus_tag="ACF3UF_002716"
     CDS             <1..493
                     /locus_tag="ACF3UF_002716"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672762.1"
                     /translation="FGNKSIKRKEVRKYCTKNRRNEMSEIDIKVYIPPYNKQNFYSLM
                     GKYFAERVYRRKLPYLINTPSTIWFLLMNKERIIGFSSIQISNEFIDIGDVFVEDEND
                     DTRKYLLEKVLFFIDKKCERKCVRISLKKDQYLNNLKHYCFKQYRETKNYLFFRREIN
                     EQD"
     gene            480..1013
                     /locus_tag="ACF3UF_002717"
     CDS             480..1013
                     /locus_tag="ACF3UF_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HFD3672763.1"
                     /translation="MNKIDMPVLNVKMVPVEKIKSNNYNPNHVAEPEMELLELSILKD
                     GYTQPIVCYYDDKKDEYIIIDGFHRYLIGKSKLDLKELPLVVIDKPLEQRMSSTIRHN
                     RARGKHEIDKMSELVLLLVNEGWDDHKIGKELGMEKEEVLRLKQVTGLKSAFLNHEFS
                     ESWDEFVKKNYPKQKDE"
     gene            1147..1614
                     /locus_tag="ACF3UF_002718"
     CDS             1147..1614
                     /locus_tag="ACF3UF_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFD3672764.1"
                     /translation="MKFCETKKVLNQLVADLSVFSVRIHQVHWYMRGERFLFLHPKMD
                     DLMEQINDQLDVISERLITLDGSPYSTLEEFFTNSKLEEEKGSWNKTIDEQIDYLLEG
                     YNYLVSTYEEGIETAGKEGDDCTEDIFIGSKSELEKEIWMLKAELGNSPELDK"
BASE COUNT         1033 a          278 c          434 g          860 t
ORIGIN      
        1 ttttgggaat aaatcaatta aaaggaaaga ggtacgaaaa tattgtacaa aaaataggag
       61 gaatgaaatg agcgaaatag atattaaagt ttatataccc ccatacaata aacaaaattt
      121 ttacagttta atggggaaat attttgctga aagagtatat agaagaaaat taccttattt
      181 aataaataca cctagtacta tttggttttt gttaatgaac aaggaaagga taattggatt
      241 ttcttccatc caaatttcca atgagtttat tgatattgga gatgtttttg ttgaagatga
      301 aaatgacgat actcgaaagt atctattgga gaaggtttta tttttcatag acaagaaatg
      361 tgaaagaaag tgtgtacgaa tttctttaaa aaaagatcag tacttaaata atctgaaaca
      421 ttattgtttt aaacaatata gagagacaaa gaattattta ttttttagga gagaaatcaa
      481 tgaacaagat tgatatgcct gttttaaatg taaaaatggt tccagtagag aaaataaaaa
      541 gtaataatta taacccaaat catgtcgctg aacctgaaat ggagctttta gaattatcga
      601 ttttaaaaga cggatataca caaccaattg tttgctatta tgatgataaa aaagacgaat
      661 atattattat tgatgggttc cataggtatt taattggaaa aagcaaactt gatttaaaag
      721 aacttccttt agttgtaatt gataagccat tggagcaaag aatgtcaagt acaattagac
      781 acaatagagc tagagggaaa catgaaatag ataaaatgtc cgaattagtt ctactgcttg
      841 tcaatgaagg atgggacgat cataaaatag ggaaagaact aggaatggaa aaagaagaag
      901 ttcttagatt aaaacaagta acagggttga aaagtgcctt tttgaaccat gaatttagtg
      961 aatcatggga tgaatttgta aaaaaaaatt atcctaaaca aaaggatgaa taagtggtaa
     1021 agatttttat aaacacgatt ttaatataaa cgttcatttt attgttgaca agatatattt
     1081 gttatattaa attatgtgta aatcagaatt atttctttta aaaaaattta aattaggagt
     1141 gatattatga aattttgtga aacaaaaaaa gtattaaatc aattggtagc cgatttaagc
     1201 gtattttcag taagaataca tcaagttcat tggtatatgc gtggagaaag gtttctattt
     1261 ctacatccta aaatggatga tctcatggag caaattaatg atcagttaga tgtaatttca
     1321 gaacgactga ttacacttga tggatctccg tattcaactc tagaagagtt ttttacaaat
     1381 tccaaattag aagaagaaaa aggctcttgg aataaaacta ttgatgaaca aattgattat
     1441 ttattggaag gttataatta tcttgtttcg acatatgaag aggggattga aactgcagga
     1501 aaggaaggcg atgactgtac agaggatatt tttattggtt ctaaatcaga gctagaaaaa
     1561 gagatttgga tgttaaaagc agagttaggt aactcacctg agttagataa atagatacag
     1621 aacttcaagt gaatggttat gatatttcct tgtgaatagg gagtgttttt cagtgtttct
     1681 atgaatacta taagtgagat tgataaaaaa acaaaaacat ctaaggagag atttatttct
     1741 accttagatg ttttttcact aagtgatctg tttcagtcga taaatataag tgcaggtaga
     1801 ttttaacaac taattatatc aaagaaataa gtatatagta ctgtaaaaat atatattata
     1861 aattatctta acaaagagtt gatgggaaca tacacaatct aatagtatgt cagatatgta
     1921 tataaaatta gaaaactgag cgaaagaaac attggaagaa tattttttaa ctatgctctt
     1981 ttatatctat atataatatg aaaatattat ttggagaaat agattctgat ggactgagaa
     2041 aaagtataaa aagctataaa aaatataaaa agaaaaaata tgctgataca cgttgtatct
     2101 attttcatcc cgaaattccc ataaagtgac agcatacttt attcatttaa tcatggtata
     2161 agaagcagct atttctactt tttgagaact taattttaag cttgcgctat atttttcgct
     2221 acaacattat aaaaaataag ttaatatgct tattttttgc tttgataatt ctaatataca
     2281 ttttcagggg caactccttc ccctgagttg cccttagaga gtgatattgg gatatccctg
     2341 aacctattat agaaatacca acatcttagc tcaacaaatt tgctttatat tgcaaaaaat
     2401 gatctaaatt atctcttttt ttatctatag attattaaat gtatggaaga attaaaataa
     2461 gataataaat tttggaaaag aaatcatatt tcaagtccta agattaacaa caaagcttat
     2521 tatatataaa taaaaactgt tcaagaatat tttcttataa atagttttat cttatttaca
     2581 aatataatag aactcagtgg actta
//
LOCUS       DAXLPY010000144         2600 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.150, whole genome shotgun sequence.
ACCESSION   DAXLPY010000144 DAXLPY010000000
VERSION     DAXLPY010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.150"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            47..484
                     /locus_tag="ACF3UF_002719"
     CDS             47..484
                     /locus_tag="ACF3UF_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672765.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            477..1172
                     /locus_tag="ACF3UF_002720"
     CDS             477..1172
                     /locus_tag="ACF3UF_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672766.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            1337..1537
                     /locus_tag="ACF3UF_002721"
     CDS             1337..1537
                     /locus_tag="ACF3UF_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672767.1"
                     /translation="MNKIIPLLLVLFVGEILMRLSAAVHLNLAVFLVILMFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            1553..1732
                     /locus_tag="ACF3UF_002722"
                     /pseudo
     CDS             1553..1732
                     /locus_tag="ACF3UF_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1794..1978
                     /locus_tag="ACF3UF_002723"
                     /pseudo
     CDS             1794..1978
                     /locus_tag="ACF3UF_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            2012..2443
                     /locus_tag="ACF3UF_002724"
     CDS             2012..2443
                     /locus_tag="ACF3UF_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFD3672768.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT          937 a          404 c          535 g          724 t
ORIGIN      
        1 cgaatattgg ttaaccaaat tagagaacta aaaaggagaa aaaaatatgg ctcaaaatta
       61 ctatgacgaa tttgtcaaat tacctttgga taaaatggca caaaaaatgg aggatatgac
      121 attcctatac aatgagacac gtgttccaaa aaaacattat aaggaaagat tgtcggtagc
      181 tgtggaagaa atgattgaat cgggtgtcga aatgaatctc attgcgacct actatcgaac
      241 gcttgaagaa ctgaaaaagc aaaatggaca atggtttttc caagccttac tatgcttgga
      301 agcaggcgtc aagccaaaca ctatcaaacc ttctgaatac caagctttag aactaacgta
      361 tgggaaattt gtcgaaacga aaaaagccaa gactgtttca agtgaatggt tggactactt
      421 agaaaatgtc aacaagtatg gcgcatgtta catcatgaaa aaggaggaca acgaaaatga
      481 ataaggtgat ttatcaacta acaacggaag atgtgtcaca ctttttaaca aacaaagaac
      541 atttgaatga agtaatcaga cggattcaaa aagactttag ttgtatggaa gaaatgaagt
      601 actttattca aagagtcgaa gaacaattgt atttggaaag tgaaacgagt caaacgaagg
      661 ttacagtcag caataattat ttagacgtgt ataaacgtcg tcctgacaca ttaaaaaaag
      721 gagcggagct tctacgacta gaaacagaaa aatatatcat gaatgtttac ctagaaagga
      781 gtgaactggt cgaaaacttt gtcagctaca cgatttgcag gaaacactat tactcagaat
      841 cagaatatta ttcaattttt gagagcatgg aattaatgga agagctaaac agcaaagatg
      901 cgacggtaga cgattattac cttgtattta ctaaattttt gacgtgtggg acggaatcta
      961 tcgtgttaat gggaatggat tatgaactcg ctgtacccga agtatttttg agggaatatg
     1021 tagaagaagt agataaccca ggcgacgact ggtacacgac tttaactgat tttttagata
     1081 cctacactta cgacgataca gaagaaatcc aaaatgaact tgaccgtaaa cgaatgccat
     1141 atcaacgatt tgaaaggaaa aaaggtcaat aaccatttat accgaaaagt gagaatgtgt
     1201 gaaataaaaa caaaaaacct tgaaattaag ggaatggttc ttatttcgca ccaatcgctc
     1261 caaccgcccc cgccgcttag gtggtgcgaa ataagcgagc aaagcccgaa aacctaagag
     1321 aaagaaggag atttatatga acaaaattat tcccttatta ttagtcctat ttgttggaga
     1381 aatacttatg cgacttagtg cagctgtaca tttaaacctc gcagtatttt tggtaatact
     1441 aatgttttgt ttgatctttt ggcgatttgt attagccctc gtaagtctac tattcaagat
     1501 gattgcagcc atatttttca taggattatt tcgatgaaag gagagagtac caatgccaat
     1561 tgcaatagga aataaacggt tacccgtgac gttggatgaa aagagacaaa aagaattgca
     1621 gtaaccaaag cagaagtacg gcaaaagtga atccaggatt atgtgtattg cgttagattt
     1681 attgattgcg caagaaaaag caggatttga cataccagca ctcaaaaagt gatcgcactt
     1741 tgcgcacgtg ttaatacgtg ttataattat tttgtaagga ggtatagtgc acaatgccac
     1801 ttacgggaaa agaaatgctt aagttattga aaaaaatggc tgggttgagc gaaggcaaga
     1861 gggatttcat catcatcttt ataaggatgg tgttagaatc actgttcctg ttcatgccaa
     1921 tcaagatctt ggccgaggac ttgagcgaaa aattttaaag gatgcgggat tgaaataatc
     1981 tcgcattcga ttaaagaaag gattgactga aatgttaagt gagcctttag caaaaaccta
     2041 tcctgctatt tttagcccag aagaaggtgg tgggtacttt attgaatttc ctgatgttca
     2101 aggtgcttac acaggaatta acgaagacga tatatcttat ggaattgcta tggcacaaga
     2161 ggtgttaggt atggttttag cagattatat tgagcatgaa gatctacttc cagaaccaac
     2221 accaatcaat aagatttctg ttgaagatga ttcttttact actttaattc gtgtagatgt
     2281 tgccaaatat ttgaaagaca cagaacttgt caaaaaaacc ttaacaattc ctcaatgggc
     2341 ggataagcta ggcaaaaggg ctggcataaa tttttcagtc cttctaacag aatcaattgc
     2401 agataaagca gataacattc ttcgttctgg aagaaataat tagaactcaa aagggtcaga
     2461 aacttaaaaa tctttggctt ctttttttac tacaaagatg gcttctttaa attatttgcc
     2521 tgattgattt aaaaaaattg cgcaaagact acgagctaat taagttgctc gtggtctttt
     2581 tttatgaaaa ctttttagat
//
LOCUS       DAXLPY010000145         2568 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.151, whole genome shotgun sequence.
ACCESSION   DAXLPY010000145 DAXLPY010000000
VERSION     DAXLPY010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.151"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            53..664
                     /locus_tag="ACF3UF_002725"
     CDS             53..664
                     /locus_tag="ACF3UF_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3672769.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            737..1666
                     /locus_tag="ACF3UF_002726"
     CDS             737..1666
                     /locus_tag="ACF3UF_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HFD3672770.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1803..2561
                     /locus_tag="ACF3UF_002727"
                     /pseudo
     CDS             1803..2561
                     /locus_tag="ACF3UF_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
BASE COUNT          896 a          358 c          480 g          834 t
ORIGIN      
        1 gaagtttata tgaagttata aaatttaatt tatattggaa ggaggaaaat aaatgtattt
       61 tatactacct acactttata gccttttatg tgtaatggca ccatgtatta tttatatggt
      121 atttttttgc aaaaaaaata ccctgaaaca caatatcctg attttgattt ttatgctgta
      181 ctgttggaaa gtttttgaat tgactggtac aggtggacta acagatattt tttatagacc
      241 tgatacaggt aggaaatttt ctctagtaca gggcagtgtt aatcttgtac cattcagtgg
      301 actaaacatt agctttatat taaatatagt aatgtgtgtg cccttaggat tcttactacc
      361 aatcatatgg aaaagttata ggaaaatagt tcctgttttc ttggctgggg ctctattttc
      421 actaattatt gaagtctcac aaattataac tacaagagca acagatattg atgatttaat
      481 agcaaatacc tttggtgcgg ttataggctt tatactgtgg gctgttttaa gtagagtggt
      541 gtccttgaag gacaagtcat ctacagtaga ttatttagaa ccttatattt atatattgat
      601 tggttttacc ggaaaattct tactgtattt tcctttctgg tttgcttttg aagtattatc
      661 ctgataattc catagaaaat aatgagtttg agttgagaaa gaatattctt gtacacaact
      721 ctggaaagga ggaagtatga aaagattctt aaaatggggg cttgttcttt tagcgtcttt
      781 gattgtgatt ctaatgtgta cagcggttgt tatttcttat gtgaatcggc cgtatgcaag
      841 agctgtttat gataggatta aacgcattct tgacaaagat ttttatgacc atctatatct
      901 aggttcttca tttgaaataa taaaccttga tacaatggat attcatagct atatgaaaaa
      961 agaccaagaa gaattacccg cctcattgag caaattattt acgattgatt atgcgcttag
     1021 tgtcctaagt ttagatgaac agattacaat tagtcctact gcacttgaca tgcagaaagc
     1081 tgactcatct actgcacatc ttcaagaagg agatatttta tctgtttatg acattatctg
     1141 tgctatggtc ttaccctcag gaaatgatgc agcttatagt ttggcaattt atacaggtgg
     1201 aaaacttgat cctgatgcaa agaatgatga agaacgctat caaagcttca tgaaaaactt
     1261 agatcgttat ctaagtgagc aaggctataa acatactcat tttactgacg ctgctggcta
     1321 tgactccaat gctacaacat cagcggaaga tttgacaaaa gtagctgcaa agctactaaa
     1381 gaatgataaa tttgcagaaa tagttgccaa ggaaacttat agagcaaaat caattaaggg
     1441 aaatgtttat aactggaata ctacgaatca atttatgcaa caagataata gatactttac
     1501 tgaaggtgta aaaggtgtaa aaactggatc gtttgatggg agatacaatc tatgtgtgta
     1561 ttatacatct agttctgata accactattt acttgtaagt tttggttcag agagtgatag
     1621 taggcgttat gtagatgttc aaaatctatt gcataatctg ccttgaaatt tcgtgccttt
     1681 aagcgcgtat ctaaagtttc tttgaaaagt ttgagaatga agaaagtgag cagtcgaaaa
     1741 acggttgctc acttttttgc cctaaaatcg aaaaaatata aaaaagtcct ttacaacacg
     1801 tctcaggaaa aactgctaag tcaattctaa tatcttgtgg agcaagactt gcaccttttg
     1861 atataagaga gcttagagaa ctaatgagcg aagatgaact agaactcgat aaaattggag
     1921 atagaaaaac tgccttgttt gtaataatat cagatacaga tgatacattt aattttgtag
     1981 tttcaataat gtattctcaa ttatttaatc tactatgtga taaggcagat gatgtgtatg
     2041 gtggaagact tccagttcat gttaggtgtc tacttgatga gtttgcaaat atcggtttga
     2101 ttcctaaatt tgaaaaacta atagcgacaa ttcgttcaag agaaatatcg gcaagtataa
     2161 tactgcaagc acaatctcaa ttaaaagcaa tttataaaga ccatgcagat acaatagttg
     2221 gtaactgtga ctctacactt tttctaggag gaaaagaaaa aacaacagta aaagaattat
     2281 cagaaacctt aggaaaagaa accatagacc tatataacac atcagaaaca agatcaaatc
     2341 aaaaatcttt tggtctaaat tatcaaaaga ctggcaagga acttatgagt caagatgaaa
     2401 taactgtaat ggatggtggt aagtgtattt accagctaag aggagcaaga ccttttctat
     2461 ctgataaatt tgatattaca aagcataaga attacaaatt gttggaagat tatgataaga
     2521 aaaacttgtt tgatgtagaa gagtatttaa aacaaagata gcgtaaaa
//
LOCUS       DAXLPY010000146         2566 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.152, whole genome shotgun sequence.
ACCESSION   DAXLPY010000146 DAXLPY010000000
VERSION     DAXLPY010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.152"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(53..910)
                     /locus_tag="ACF3UF_002728"
     CDS             complement(53..910)
                     /locus_tag="ACF3UF_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFD3672771.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(1195..1482)
                     /locus_tag="ACF3UF_002729"
     CDS             complement(1195..1482)
                     /locus_tag="ACF3UF_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD3672772.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKIIPVLLCGTHEKFYEQLKKLI"
     gene            complement(1472..1801)
                     /locus_tag="ACF3UF_002730"
     CDS             complement(1472..1801)
                     /locus_tag="ACF3UF_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3672773.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(1878..2150)
                     /locus_tag="ACF3UF_002731"
     CDS             complement(1878..2150)
                     /locus_tag="ACF3UF_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFD3672774.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(2150..2413)
                     /locus_tag="ACF3UF_002732"
     CDS             complement(2150..2413)
                     /locus_tag="ACF3UF_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3672775.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT          772 a          517 c          337 g          940 t
ORIGIN      
        1 tggcgagtcc tttattgttc ccaaaaatat caagtccttt gatgtcagcc aattactcca
       61 cctccgcata ccaattctcg tgttcttcca attctttcaa aatactgata aataattcgt
      121 ggcttttgcg atcccattgt tttaagagac ctttctttgt cttctccatc gtaatacctg
      181 atccgtcgta tcgttttaag cgcgcatttt tgagtacaac atttttaatc aaatgttccc
      241 cataaatctc ttgggcttgt ttatacattt cctgatctac tgcgtcaccg ctttccaaca
      301 tgaaaggaat aacaccagca acatataaat ttgtatcaaa ttctttcaca aaaaagtcca
      361 tatactcaag atattgcatc gcatttctca tcgattttac ttgggtctgt aagacgacga
      421 ttgcccagtc cgcaatgtac atcgcggatt tactatatac agaaatagaa ggtgggacat
      481 ctaaatagat gacgtcaaac tcatcaaata atggttctag cttttctttc atatatttga
      541 attgggataa tgaatcatta tattggtctt tgatccaatc atcatacatt tcaaaggaca
      601 tgtctgctgg aagtatatag aggttattga ttactttata gacagcctct ttaggtggaa
      661 gattgtttat caacacgtca gtcacagtat tttcgtaaac aatcggttca ccttctccgc
      721 ctccttcttc gttagtgaag ttcatatgcg ttaagttcat cacatcagaa gtatttcctt
      781 gcatatccaa gtcaattatc aaggttcttt ttccttcatt aactgctgat tcaaacccta
      841 acatttgcgc gcacgtactt ttacctacgc cacctttaaa attaccgatt acatatttct
      901 tcgctaccac gttcctacct cttttctttt agcaatattc atttgatact attataacat
      961 atttattttt agttactacc aaaaaaagat atatatgtac taccttataa ttaataagga
     1021 aaaggtagta cataaataag gaaaagctga aatatattga tttatagctt tcctcaaagt
     1081 aatgacgtta tttaatttat cgagaagcag agaatactcg cgactttagt catgtagacg
     1141 aatcagattt tcgataaaaa agaagccgtc cttcttaaga acgacaacaa atcactagat
     1201 taattttttc aactgttcat aaaatttttc atgcgttcca cataacaata ctggaataat
     1261 cttgttttct ataatctcgt aagctactct atatgttgtg cccgcatatt taaacccact
     1321 agaccaaata cctgataaat ccccagtttt ttgttcaccc ttatatggat caatcgcaat
     1381 ttcatcataa attaaattca aaaatttttc tttcaatggc ttctctttta gcttttttaa
     1441 atacttaatg acatgttttg aaggaacgat ttcataagcc aatttctgtt gccaactcct
     1501 ctttagtcat tactttagaa ttagtaagtg tatcttcagc aatatctcta aaggaagaat
     1561 gcattttgtt ttttctattc ttaaattcta caagaatctc atctttatcg tagccttctg
     1621 caattatatc agacaaaata tcttcgctaa aatcataaaa ttctttttgt ggttcaacaa
     1681 attcataaag aataccattc tctaccaact ttgcttcaac ttcgactcca ttaggaacat
     1741 taaaatcttt aggtactgtc aacatgattg aattgccttg ttttcttgtt tttgtaatca
     1801 tttaaatccc tcatttctaa cagtatgtaa ttacttagta aatacattat accacgagat
     1861 aatgtattta caagtaatta ctgtgactcg taatgcgtcc ttgctgaata aatttcaacc
     1921 acgtgttcat cttcatctac cttataaaca acccggtgtt gtctattcaa tcttctagaa
     1981 tacctacctt catgtgtagg ttttaacttc tcaaatgatt gggtagggag atagggatct
     2041 tcctttaaag tctgaataac cttctcaaat tgaggtttca aattagactg tttgattttc
     2101 tttaaatcag ctttagccga gtttttaatc atcacagaat agttattcat tataagttat
     2161 cccaatcaat ttcatcaaca ttagtaaatc cactatcatc tttttctcgc ttacgaacaa
     2221 cacccaaagt gcctatttgc tcaagtaata gcgtttcttt gattgctttc caatcatcca
     2281 aaccaataag caccgcatta ttttcactgc gctcactaat gatttcaatt tccgtatgat
     2341 tctcatttac atctttcaac aacttataaa aatttttccg tgctgagcta ggatttaaga
     2401 ctgtttttgc catatctact ccccctctaa tttatatctc cattctaacg tacttaatta
     2461 agtacgtaaa ttcgattgtt ttgtttaaat tggagtacca aaacagcatt gtaaagtgtt
     2521 atccgtttcc tttatacccg tggtgctagt taattttttc ctagag
//
LOCUS       DAXLPY010000147         2509 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.155, whole genome shotgun sequence.
ACCESSION   DAXLPY010000147 DAXLPY010000000
VERSION     DAXLPY010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.155"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(489..614)
                     /locus_tag="ACF3UF_002733"
     CDS             complement(489..614)
                     /locus_tag="ACF3UF_002733"
                     /inference="COORDINATES: protein motif:HMM:NF019687.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672776.1"
                     /translation="MLFPPFKSSKSRKNPSDKYSYHWDFNTKIAVYYTLIATDAL"
     gene            599..>2509
                     /gene="tet(S)"
                     /locus_tag="ACF3UF_002734"
     CDS             599..>2509
                     /gene="tet(S)"
                     /locus_tag="ACF3UF_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HFD3672777.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVR"
BASE COUNT          900 a          372 c          441 g          796 t
ORIGIN      
        1 atgatatttt ccaagtcaaa cttaatatta acaattcaaa actattggaa ccactgcaaa
       61 atattttgtt aagcagtata tatttcaaaa attatacgta atatatttgt agaaaggttg
      121 tggacagttg tcctattgac ctgaaaagta atataatagc tggatgaata aagaatccct
      181 tatgaacttg taaatcgtta ttaaatcgct gaattttgat agccattctg aagagttatc
      241 ttcaactact acactaactt ccattaattt ctcattaatt tccctttcgt tcaaaaaata
      301 tggttggctt tacaagcatt ctatcatatg atagaattaa gataacattc aaaaggagat
      361 aataaaaatg cggcaaggta ttcttaaata aactgtcaat tagatagcgg gaataattaa
      421 ttaagcatcc ttatttaaaa taaggactgg ttttttgtgc ccagtttaag aatactttta
      481 tcattttatc ataaagcatc tgtggctatc agtgtgtagt atacagctat ttttgtatta
      541 aaatcccagt gataagagta tttatcactg ggattttttc tgctttttga gcttttgaat
      601 ggaggaaata aaattgaaaa ttattaatat cggtatctta gcacatgttg atgcaggaaa
      661 aactactttg acagaaagct tactatacag tagcggagca attaaagagt taggaagtgt
      721 agatagcggt acaacgaaaa cggatactat gtttttggaa cgccagagag gtattactat
      781 tcagaccgca ataacatctt ttcaacggga aaatgttaaa gtaaatattg tagatactcc
      841 tggacacatg gattttttgg cagatgtata ccgttcatta tctgttttgg atggagctat
      901 tttgctaatc tctgcaaaag atggagtaca gtcacaaact cgtatactat tccatgcact
      961 tagaaagatg aacataccta taatattttt tattaacaaa attgatcaaa atggaataaa
     1021 tttgccagat gtttatcaag atattaagga caaactttct gacgacatca taattaagca
     1081 gactgtgaat ctaaatttga aaccttatgt aatagattat actgaaccag aacaatggga
     1141 gacagtaatt gtgggaaatg attatttatt agaaaaatat accattggga aaacattgaa
     1201 tattgcagaa cttgaaaagg aggaaaacga aagaattcaa agttgctcct tatatcctgt
     1261 ttatcacgga agtgcaaaga ataatattgg aattaaacaa cttatagagg taattactag
     1321 caaattattt tcacccacac aactcaattc agataaactt tgtggaaatg tttttaaagt
     1381 agaatattca gatgatggtc aacggcttgt ctatgtacgt ctttatagtg gaacgctaca
     1441 tttgcgagac tcagtcaata tatcagaaaa ggaaaaaata aaagttacag aaatgtatac
     1501 ttcaataaat ggagaattac gccagataga taaggcagag cctggtgaga ttattatttt
     1561 aaaaaatgag cttttaaaac taaataacgt acttggagat aaaaaaagat taccacatag
     1621 agaaattctt gagaatcctc ttcctatgtt acaaacaaca attgaaccat gtaaatcagt
     1681 acaaagagaa aagttactag atgcactttt tgaaatatcc gatagtgatc cccttctaca
     1741 atattatgta gatacagtaa ctcacgaaat tgtgctatct tttttaggtg aggtccaaat
     1801 ggaggtaact tgtactctga ttcaagaaaa atatcatatt gagatagaaa caagaaaacc
     1861 aactgtcatt tatatggaaa gaccattaaa aaaatctgaa tttaccattg atatcgaagt
     1921 acctccaaat cctttctggg cttctattgg tttatctgta acaccacttc ctttgggtag
     1981 tggcattcag tatgagagcc tggtttctct aggttattta aatcaatcat ttcaaaatgc
     2041 agttatggaa ggtatacgct atgggtgtga acaaggattg tacggttgga aattaacaga
     2101 ctgtaagatc tgttttaagt atggtctata ttacagccct gtcagtacgc cagcagattt
     2161 ccgaatgctt gcgcctattg tactagagca ggcttttaga aagagtggta cagagttatt
     2221 agagccatat cttagcttcg aaatttatgt accacaagaa tatctttcga gagcatataa
     2281 tgatgcttcc aaatattgtg caaatatttt aaatactaag ttaaaaggta acgaggtcat
     2341 tctcattggt gaaattccag cccgttgtat tcaagagtat cgaaacagtt taactttctt
     2401 tacaaatgga cgcagtgtct gtttaacaga gttaaaaggt tatcaggtta ctaacattaa
     2461 gtctgctttc caaccacgtc gtccaaataa tagaatagac aaagtaagg
//
LOCUS       DAXLPY010000148         2489 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.156, whole genome shotgun sequence.
ACCESSION   DAXLPY010000148 DAXLPY010000000
VERSION     DAXLPY010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.156"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            192..446
                     /locus_tag="ACF3UF_002735"
     CDS             192..446
                     /locus_tag="ACF3UF_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3672778.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            447..764
                     /locus_tag="ACF3UF_002736"
     CDS             447..764
                     /locus_tag="ACF3UF_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD3672779.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1323..2258
                     /locus_tag="ACF3UF_002737"
     CDS             1323..2258
                     /locus_tag="ACF3UF_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672780.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
     gene            2352..>2489
                     /locus_tag="ACF3UF_002738"
     CDS             2352..>2489
                     /locus_tag="ACF3UF_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFD3672781.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
BASE COUNT          920 a          343 c          460 g          766 t
ORIGIN      
        1 ggatgttaac ggaagtgtat ggtgagtagt tcactcgtat tttgatatcg tttgtatatg
       61 ttttcagcgt tctaagtggc ttattttgtc caataataat atggagtgga atcccttaag
      121 aaacaccgtt ggcaattgtt gttataacat gttataattt attcatcaaa aactaaaagg
      181 agtgtgataa catgggaaaa gaactaaagg ttagaaagat cggcaatagc gtgggagtga
      241 tccttccaag ctctcttgga ttaaaaagcg gagacattat ccaagccaaa caagaaggca
      301 acttattcat attagatact actcaaatag caaaagaaca cgatcgcaaa ttgattgaag
      361 aaagtttcca agactttgag aaaggtttaa cagtttcaga aattgaaatg gtaaaagctt
      421 tcggaaaata cggctggagt gaatagatga aagagtacac gctagtttat tctaaaagtt
      481 ttcagaccag ccttgaaacg ataatagaag aatgggaaaa tgagcttgct ctttctccag
      541 ccagcataaa aagatttgta ggtgcgatcc agaaggcttt agaactaacc aaaaattttc
      601 caactatgca tgaggaagtt tccgaaatct atggaatgga tatcccaaca tatcggatcg
      661 tgatcggcaa aagctatgcc ttattttatc ggatcgacca tgaaaaaaaa gagatacttg
      721 taggacgtat tttccaatct aaacaaatga aactaggctt ttaacaataa ttaggaaaaa
      781 gtcgctcatc ctctacaggt gggtgattaa tgccgctcga tatggttgtt aaccgtcggt
      841 tactcgaaga ttgatatata agacttagta cctttttatt ttgctccatg ttatggccga
      901 aggtctaaag atacaatcat tagtctagag aaaaattaag aaccgtagga actacgggga
      961 tcgcttggtg aataagagac actgctatta gtgaaaaaat aagatatcaa gtacgctcta
     1021 ttcccaaaaa tttcgtgact ttactcatga gaggttcaag tagtatattt ttaatcaaaa
     1081 ttgacgtaac ttttaataaa tactacctaa ataaggtagt atttattttt gtgttttaaa
     1141 agaggaagtc caatatatct atgggaaact tcttaaatat tatgttggta catgaaaata
     1201 tacatccctg ctagactatt tacaacattt tactttgtac gtattcttgt tttaaaagga
     1261 atgggataaa atataggtac aataactatt tgatgctaaa tataattaat ggaggagaga
     1321 tagtgaacat acttaatgaa aaaagatatg tatggtttgc tggtaaaaaa tatattacta
     1381 ctttcaaaag attatccgag ttaatgcagc agactgttaa aagtgctatg cctgaaggat
     1441 acaagtttaa ttttgttcaa tcttcagtat ctactgaaag tatctatttt tcaattcttt
     1501 ctgagagtag gctttttcat tttagaataa gttctcatgt aaagaaaact gatgttgata
     1561 tatatacgtt ccgtacaaat aattataaaa atttaaatga tttgagtaga agtatcagtg
     1621 aatatctcaa ggggaatagc tatctcaaga ttcgattttc acatatatta attttactac
     1681 catatttgaa tgagaatttc accctaattc aagtagataa gtctttcatt gcctcaggta
     1741 atcaaggaaa tatgaatatt acaagtaaca aaacgtcacg tgtgctattg gcgttgatgg
     1801 gttacggaat tctttataga gatgaccaaa atggccagat tctaataaat cgggctgggc
     1861 gttcattatt aatgaaatat agaaaattta taccggaaga ttttcaaaac ttacagttag
     1921 aaaacatgcg tttagaagat ttatttagat tagcagaaga tgataagtat agatttgaag
     1981 ttttgaaaat tcaaaagaat gaactattga ataagttata tcctgagaat gcgataaaag
     2041 cacattttgg tgatgctaat catatgtata gttggttcat tcctaaaaga tttagaggga
     2101 aaatcaatgc tggagatcaa gtgaaagtac tcaatcgaaa tagtacagat gtcgtaatga
     2161 taacagatat ctatgtagaa gatgaagata taatcaaata tatgaagcct gtgataaaac
     2221 ttgttaataa aaataaagga acccgtggtg ctagttaatt ttttcctaga gaaaaatgtc
     2281 taaacatgtt ggtaaatcaa caaaaaaacg catagagtag tctcaaaact cccaagaaat
     2341 gaggactaca tatgcgttca tcaaaatata ctgaacatta tacagatact tttataacat
     2401 tcaaggaaat tatgagaact gtttctaaca tataccacaa ttgtgtacca gataagatta
     2461 aaaaccgaag aaatactgat caactgaag
//
LOCUS       DAXLPY010000149         2476 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.157, whole genome shotgun sequence.
ACCESSION   DAXLPY010000149 DAXLPY010000000
VERSION     DAXLPY010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.157"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            34..1158
                     /locus_tag="ACF3UF_002739"
                     /pseudo
     CDS             34..1158
                     /locus_tag="ACF3UF_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1578..2222
                     /locus_tag="ACF3UF_002740"
     CDS             1578..2222
                     /locus_tag="ACF3UF_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3672782.1"
                     /translation="MYKTANELFNRLKSEKKELILNYILEEFGRVGYESASVRKIADK
                     ADLSAGSLYQYFNNKEGMLRVAIEHVFVILDEYINNINNAPLKLENRLEVMFETILEL
                     GRKHPELIVFYNKIPGDEQMTSEWVKQFYNNTSFFKVYWHTVNELQDEKEISDKIDPV
                     VYTFIIDTMMLSGELLQNTQYQEIKAKIFLEDSIKSSLILKENVIETLTVLARG"
     gene            2229..>2476
                     /locus_tag="ACF3UF_002741"
     CDS             2229..>2476
                     /locus_tag="ACF3UF_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3672783.1"
                     /translation="MTISNKNSMREEIIIIAIKHFSKFGYEKTRLLDIANEAKTSTTT
                     VYSFFKTKHDLYEAAVEYDLNIINLELEKIVKESSTLD"
BASE COUNT          936 a          350 c          470 g          720 t
ORIGIN      
        1 aaaatataag aaaacacact ggaggaattg ttaatgtcag aaagaaaacc acgtcgaacg
       61 tttactaaag agtttaaaaa tcaaatggtt cagttatatg cgtcagggaa aaagagaacc
      121 gatattatca gagagtatga tttaaccccg tctacttttg ataaatgggt gaaacaagca
      181 aatacctctg gctcatttaa agaaaaagat aacttaacac ctgaacaaaa agagttaatt
      241 caattgcgaa agcaaaataa acaactcttg atagaaaatg atattttaaa gcaagcggcg
      301 ctgatattcg gacgaaaaga caagtaattg atgcaaataa gcacaaatac tcgatatcag
      361 ccatgtgtaa agtactgggt attgcaagag ccacctatta ttatcgagaa aaagaaacga
      421 ctcaaggcgc agtagaagca aaattagaag aagcggtgga agaagttttt caacaaaata
      481 gacgagcata tggttcacgc agaatcaaga aacgccttga taagaaaaat ctcattttga
      541 gtcgtcgaaa aattcgtcgc atcatgaaaa gacgaggatt gaaatccagt tacacgaagc
      601 ccaaatatcg cgtacattcg tgccaaagca atcaaaagaa aattgcgaat cacttagatc
      661 gaaagtttac tcaaacaaaa gcattgtcag cggttgtcac ggatttaact tatgttcggg
      721 tcgggacaaa ttgggcttat atttgtttga tgattgattt attcaatcgt gaaattattg
      781 gccattcttg cggaaataaa aaagatgcgc agcttgtaaa aagggccatt caaagcattc
      841 cttactcact tcaagaaatc gaactcttcc atacggatcg tggaaaagaa tttgataatg
      901 aattgattga tcttatctta gaaacatttg gcattcaacg ctccttgagt aagcctggat
      961 gtccatatga taatgccgtt tcagaagcga cttacaaagc ttttaagacg gaatttgtga
     1021 gtcaatatca atttgaaacg atggcacact tagaattaga atgttttgat tatgtcaatt
     1081 ggtggaatca tcatcggatc catagttctc ttggttataa aacaccaatt gaggtacgct
     1141 atgcggaggt tggcgtagcg aacccttgat aatgagcaag aatcggttac cttctgttcg
     1201 agcggcttat tttattcaaa gtgagcacgc cgctaagaaa accgatttga ggaggctcgt
     1261 tgtcaagggc aactggatat ggtgtcataa acagacctta taatttttgt ctagaaaagt
     1321 gttgccattc catacatcta gagttatttt atatcccctt gaaagtcagg agtcttgtaa
     1381 agaataatga aaatattaag acttctgaaa ttaagtcggg tcacacttct gtaaatagtt
     1441 cagacgaaat tattagtagt agaaaagtaa atggttggaa aatgattcaa ttaggagaag
     1501 ctttaaaaaa tgagcggtcg tttttataag gttaatatgg tatacttagt tataatatct
     1561 tttttgagga gatagctatg tataaaacag caaatgaatt atttaatcga ttaaaatcag
     1621 aaaaaaaaga actcatttta aactatatct tagaagaatt tggaagagtt ggttatgaat
     1681 ctgcttcagt tcgtaagatt gctgataagg cagatttaag tgcaggatca ttatatcagt
     1741 actttaacaa taaagaagga atgctaagag tagcaataga acacgttttt gttattttag
     1801 atgaatatat taataatata aacaatgctc ctttaaaatt agaaaatcgt ttagaagtaa
     1861 tgttcgaaac aatcttagaa ttaggaagaa aacatcctga attgattgtt ttttataata
     1921 aaattcctgg tgacgaacaa atgacaagcg agtgggttaa acaattttac aataacacta
     1981 gttttttcaa agtatattgg cataccgtaa atgaattaca agatgaaaaa gaaataagtg
     2041 ataaaattga tccagttgtc tacacgttca ttattgatac gatgatgtta tccggagaat
     2101 tacttcaaaa tacgcaatat caagaaataa aagccaaaat ttttctagaa gactcaataa
     2161 aaagttcatt aatattaaaa gaaaatgtta tcgagacgct aactgtactt gcaagggggt
     2221 aagagtctat gacaataagt aataagaata gcatgcgaga agaaattata attattgcta
     2281 taaagcattt ttctaaattt ggttatgaga aaacaagact tttagatatt gctaatgaag
     2341 ctaaaactag tactactact gtatatagtt tttttaaaac aaaacatgat ctgtatgaag
     2401 ctgcagtgga gtatgattta aatataataa accttgaact tgaaaaaatt gttaaggaaa
     2461 gttctacact cgatga
//
LOCUS       DAXLPY010000150         2414 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.158, whole genome shotgun sequence.
ACCESSION   DAXLPY010000150 DAXLPY010000000
VERSION     DAXLPY010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.158"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..300)
                     /locus_tag="ACF3UF_002742"
     CDS             complement(<1..300)
                     /locus_tag="ACF3UF_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFD3672784.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACF3UF_002743"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACF3UF_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACF3UF_002744"
     CDS             complement(1014..1304)
                     /locus_tag="ACF3UF_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672785.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2204)
                     /locus_tag="ACF3UF_002745"
     CDS             complement(1512..2204)
                     /locus_tag="ACF3UF_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFD3672786.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          705 a          447 c          343 g          919 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgagtttc tacatttgtt
     1681 ttttcttgtg tcagtgttgc gatttgttga ttcaaaccat ttacagtatt ttgtaattct
     1741 gaaagttttg cttgtgcttc ttgtagtctt gctgtccaat ctgcattcag atgattgatt
     1801 tcatcatttt tttggttgat ctcatctagt ttgacattga tttcattttg tttgctttgt
     1861 agttgtgcat ccttgctgac taattgactt tctaagtttt gtttttctgc tgccgattga
     1921 tttttttggt tttctaattc atttactttt gtttggtatt cttggacatc tgcctttgaa
     1981 tcttgcaatg tctgttcttt ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct
     2041 ttatctgtca atgtatgatc aagctgtgtc agattctcat tgattgtatc aatatctgtc
     2101 tctccacccc acaaaataat ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat
     2161 agaaatgcaa cgacaatccc accagtaata aatttctttt tcatttgcat agctccttaa
     2221 tccaatactt ttacatgcta aaagtaagtg atctcaaaca caatgtcaag cgtttttaaa
     2281 ttacatatgt aattttaata taaatactat caaatactca tttaatcctc cttttttatc
     2341 tatttaaaaa atctttttta tagagaaaaa tgcaggttaa tactttctta aataaatatt
     2401 tatggtgaac aaaa
//
LOCUS       DAXLPY010000151         2357 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.159, whole genome shotgun sequence.
ACCESSION   DAXLPY010000151 DAXLPY010000000
VERSION     DAXLPY010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.159"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..352)
                     /locus_tag="ACF3UF_002746"
     CDS             complement(<1..352)
                     /locus_tag="ACF3UF_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672787.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGD"
     gene            complement(465..722)
                     /locus_tag="ACF3UF_002747"
     CDS             complement(465..722)
                     /locus_tag="ACF3UF_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672788.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(1319..1597)
                     /locus_tag="ACF3UF_002748"
     CDS             complement(1319..1597)
                     /locus_tag="ACF3UF_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672789.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(1631..1882)
                     /locus_tag="ACF3UF_002749"
     CDS             complement(1631..1882)
                     /locus_tag="ACF3UF_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672790.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT          739 a          472 c          316 g          830 t
ORIGIN      
        1 cgtccccaaa aggtagatct tctctaccac tagctaatct acttctccat cttcgttctc
       61 ttttcataga acctgcgctg aactcacacc cgttaaactc agctatgaca gtatcttcaa
      121 ttatgttaat ctgtccatct agttcgtatt caatcctaaa tggaaattct ccataggtga
      181 tttccggttc gggtatttta ggtgagatta atgcaaagaa aggaaatatt aagcttggca
      241 acatcaaaaa aactcctcct atgatcacaa ttcccgatgt aatccaaaat ataatttgta
      301 caattctcat tgatccattg tattccattt tattccccct attactattc atatccgcct
      361 atctatatcg atcttccaat gcagagataa ttgcttccat accttgattt tttactgagt
      421 tacctatgcg agatatcatt ctccactaag gtgcatcata ttgtctatct aacatgatta
      481 attctccaat aggtgtatac tcctccaaaa acaacattta atgcatctcc ctcgacaaca
      541 taagctacca tgtttgctgt atatgtgttt gagtctaatt cataagcaga taaatttact
      601 gtcgctggat taaatataat cgcattcgta tttatagcta ctgaatttgc tgcttcagca
      661 ccaccttttg aatgtccgat cattgtgatt tcaatagtag gatttacgtg gacagccctc
      721 accgtttacc ctgaccatta tagaaatcgc ttactttttt gaactacgca acaaaggata
      781 caatgctcct aacttcactg tctccatttt tgtccactaa ggaatataaa aaataggcat
      841 taattcattt aattcggtca caacacgtta ccttttaaat cattatactg tatctcatac
      901 attattatca ataaactatt ataaaaatgc aaaaaatgct ttatcaatct attttgtaat
      961 tggtcataat atcattgaaa tcataccctg tatcgatttt tcctatgaat ctcgtctatt
     1021 tgtgattgac gaaaaagagg caagacagac actggaatgg taattttacc cactattttg
     1081 ctccaactat ttgtaatcgt acccactttt gaaataccga gatgatcatt ttaattgata
     1141 tgctgattcc caagcaaaac cccaagaaat taaatgctct atcgcatcta gcttcttggg
     1201 ttttgcttat ataaattcca acatttaaat tttttatgct gttcggtctc agaaatgccg
     1261 tttttgctta tatcacaata tcaagatgtc aaattattcg tgttgccgat gactttgatt
     1321 aatttttttc aaattgttta ttaagactaa tgctgtcttt ttgcagatac caatgttcga
     1381 actttttaac attatcatat gatcctgcaa gttttaactt cttaccatta gatgttatca
     1441 aagttataat taaccttgcc tttttcccat taggatcttt tattttatga attttctgca
     1501 ggtaatctct cctaatggca gctattttta cctcatcagt gctgataaac cattgatcat
     1561 ccacatacat actgcctgtt atgttgtgtt tttccatttc ttccgagaac gaaaagttta
     1621 aggctcgttc ttacttccaa agttgaatga gtccatggat tggacttagt gtgagaattg
     1681 agaacaacaa taagaatcca tatcctcccg caaacatccc taaggctata ctgtctctcc
     1741 atccataagt aggattagaa gagaaaagag tcaccgtttg taataatatg aaaaggaata
     1801 atccagcaca aacaccaaag ataacaactc caaacattga atttttatac aatgaccatt
     1861 tatttatagg cttttctttc attttacttc cccctactgt tctgttcaca cggaatgaat
     1921 tcaaagttca taagccctcc tctttgaaca tatgaatacg acttgctaac tatactttaa
     1981 aaaagcttgt tttaagcggt tataggcgag ttgtaatctc tattcatctc attagcaaat
     2041 aacttgccga aaagtctact gaaattaaag cagatagtgg aagaattatt tagccaggat
     2101 agacactatt tgtgaaacac atgtctttac ttttgaaatt ctatgatgaa aagccttgga
     2161 atacagtagc tcttaattgg taatactttt tccattataa ataacctctt ttcattttat
     2221 atttatcccc tctaaaaata atatctaatc taatatttta aacttatatt tccctcgctg
     2281 tgctaataga gcattactaa ataaatagaa actagaaaaa agcattacgc ctgccagaat
     2341 aaaccaatta tttgtat
//
LOCUS       DAXLPY010000152         2320 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.160, whole genome shotgun sequence.
ACCESSION   DAXLPY010000152 DAXLPY010000000
VERSION     DAXLPY010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.160"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            201..1097
                     /locus_tag="ACF3UF_002750"
     CDS             201..1097
                     /locus_tag="ACF3UF_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672791.1"
                     /translation="MEINLFEAGNRIKQIREKHGYTMADLGKLVDANSPSTINNWEKG
                     NNLPNRKRLEKIALLGGTSVEWIKYGDFSDYVYRLTQNIEEKILKEYGETTLNNYREA
                     LLDELTIEKITYEEDTKILAAAEKINTQNIFQEVKYMYSPDEDYRNIEVKPDLGLTDD
                     NKNIKMIGQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAE
                     IGGVSELYLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKID
                     DPDKREISLNAICQLSLLDKMG"
     gene            1146..1520
                     /locus_tag="ACF3UF_002751"
                     /pseudo
     CDS             1146..1520
                     /locus_tag="ACF3UF_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353455.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1800..>2320
                     /locus_tag="ACF3UF_002752"
     CDS             1800..>2320
                     /locus_tag="ACF3UF_002752"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672792.1"
                     /translation="MTQTDFAELMGLSRSYIGDLENNRSNPSIKTLEAIARALDVPIV
                     ALINDSSTDNIVEPYESLTAENILLKQENEELKYEVESLRKRLYEIQQVVNQGAEKMI
                     PNLKDVSKRIKYIRKKLGMTMEQFGSHLSNSPKSTIATWESGRNIPSQKKLQLIAIVG
                     ETTTDWIKWGTLE"
BASE COUNT          906 a          324 c          434 g          656 t
ORIGIN      
        1 ggttgaattg atagatggac tcaaagaaga aaattcaaag ttaaaagaga agataaaata
       61 ctatgaatgt ttatttgatg gtatagagag tctgctgaac tcacgaaaaa atccctagtt
      121 tttatgaatg accgttttgt aaatctgatt gaaatagatt tatatgattt cggtatatga
      181 tatacattag gaggtgtcga atggaaataa atctttttga ggctggtaat cgaataaagc
      241 aaatacgaga aaaacatgga tatactatgg cagacttagg taaactggtt gatgccaata
      301 gtcctagcac aattaacaat tgggaaaagg gaaataactt acctaataga aagcgtcttg
      361 aaaaaattgc actattaggt ggtacttctg ttgaatggat aaagtatgga gatttttccg
      421 attatgttta tcgcttgaca caaaatatag aggaaaaaat tcttaaagag tacggagaga
      481 ctacactgaa caactaccgt gaagctcttc tagatgaact tacgattgaa aaaatcacat
      541 acgaagaaga tacaaagata ttagcagctg ccgaaaaaat caatacacaa aatatttttc
      601 aggaggtgaa gtacatgtat tctcctgatg aagattatcg aaatatagaa gtcaaaccag
      661 atttaggact gactgatgac aacaaaaata ttaaaatgat tggacaacgt ataaggaaaa
      721 taagaaaaaa agagaatatt acattagaag aattcggcaa actattctct cctacagctg
      781 ataaagctgt tataagcaac tgggaaaatg gtaaaaacct tcctaactca gaaagaatta
      841 aaaagattgc agaaattggc ggagtttctg aactttatct tatgacgggt gtcgattcaa
      901 gcgtagcaga atcaatgtat tttctatctg aagtagcatt ggatgctttg gaacgtctgt
      961 caattgagga agtcaataga ataattgaaa gcttcgccgg ttatcttaat gtgatttcaa
     1021 aaattgatga tccagataag cgagaaatat ctctcaatgc tatttgtcaa ctatcacttc
     1081 tcgataaaat gggttgattc acaaaaaata ttgaaagatt actttactca cgaggaggct
     1141 tagctatgaa acctaatcta tcgttaacta gtgaacgtat tagaaaaatt atcgaatcca
     1201 aaggtctgac attagaacga ttcggtgatt taattggcga cacaccaata agttctgtta
     1261 ataattggct tagaggcgtg tctttaccca ataaaaatag gcttttaaca attgcaaata
     1321 ttggaaacac tagtgtagac tggattaaat ggggaacttt ggaagaatac atagcttcat
     1381 accttataga ttcaggttat gagctatata ttaaagactt tccagagata ccttacaaag
     1441 tctttaaaga cattcaagaa aaatatagtg atacgttttc actagataaa gactatgagt
     1501 tattgaatcc tataataaaa tttactatag ggggcgttac tttgaataga ataaaatttt
     1561 atattgattc cagtaaaaag accattaaac aaattagtac agaaactggt attaactata
     1621 caactcttac gaactattac cgtggtgagc gaaatcctag aaatactgaa acatggaata
     1681 tccttgctga ttatttccat gttcctgtaa gttatttgat gggattagac gaaacaaatg
     1741 ttgaactcaa aaaccttaat attggaaaca acatcaaaaa tattagaaaa agtaaaaata
     1801 tgacacaaac tgattttgct gagttaatgg gtctatcacg atcatatata ggggatttag
     1861 aaaacaacag gagtaatccc agtataaaaa cactggaagc tattgcaaga gcattggacg
     1921 ttccgatagt agcattaatc aacgattctt ctactgataa tatagtagag ccgtatgaaa
     1981 gtttgacagc cgaaaatatc cttcttaaac aagaaaatga ggaattaaaa tatgaggtag
     2041 aaagcttacg aaaaagattg tatgaaatcc aacaagtagt aaatcaagga gctgaaaaaa
     2101 tgattcccaa tctaaaagac gtaagtaaaa gaatcaaata tatcagaaaa aaattaggta
     2161 tgactatgga gcaatttggt tctcatttaa gcaactcacc taaaagtaca attgctactt
     2221 gggaaagtgg tagaaatata ccttctcaga aaaagttaca gctgattgct atagtaggag
     2281 aaaccaccac tgactggatt aaatggggaa ctttagaaga
//
LOCUS       DAXLPY010000153         2264 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.161, whole genome shotgun sequence.
ACCESSION   DAXLPY010000153 DAXLPY010000000
VERSION     DAXLPY010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.161"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..503
                     /locus_tag="ACF3UF_002753"
     CDS             <1..503
                     /locus_tag="ACF3UF_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672793.1"
                     /translation="SNLIFEGKNLFLNLTISFEKDYHKLDFKEGAELTIKFTDLCSGK
                     CLVNNQSVIDFGDSKYISNFKNKIKAMKSREQSRGVFSKGGHGRKRKLDQDRWEAIKK
                     RESNFVKTYNNQCSAKIIQTAIRNKTQIICISEPDKNYGEWAYYQLKEQIINKGKRYG
                     IEVKSE"
     gene            complement(1063..1440)
                     /locus_tag="ACF3UF_002754"
     CDS             complement(1063..1440)
                     /locus_tag="ACF3UF_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFD3672794.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(1486..1674)
                     /locus_tag="ACF3UF_002755"
     CDS             complement(1486..1674)
                     /locus_tag="ACF3UF_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFD3672795.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            1980..>2264
                     /locus_tag="ACF3UF_002756"
     CDS             1980..>2264
                     /locus_tag="ACF3UF_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672796.1"
                     /translation="MKPNPVETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERG
                     FSLPNKERLIKIAELSNKTIDWIKWGTLEEYITSYLIGIGYELYIKDFPEI"
BASE COUNT          825 a          325 c          417 g          697 t
ORIGIN      
        1 agagtaatct aatctttgag gggaaaaatt tatttttgaa tttaacaatt tcttttgaaa
       61 aagattatca taagctagat ttcaaagaag gagctgaatt aaccataaag tttactgatt
      121 tgtgtagcgg taaatgttta gttaacaatc aatctgtgat tgattttggt gacagcaaat
      181 atataagtaa cttcaaaaat aaaattaaag caatgaaatc aagggagcaa agccgaggag
      241 ttttttctaa aggcggtcat ggtcgaaaaa gaaaattaga tcaagataga tgggaagcca
      301 taaagaaaag agaaagcaat tttgttaaaa cctataataa tcaatgttcg gcaaaaatta
      361 ttcaaacagc tatccgcaat aagacgcaaa taatctgtat ttctgaacca gataaaaatt
      421 atggggaatg ggcttattat cagttgaaag aacaaataat aaataaaggg aaaagatatg
      481 gaatagaagt taaaagtgag tagaataaga aatcgttgat ttggcaacga aatagtgagg
      541 ggacactcac tcactgaagg gttagctctg tcaagttgtg taaccagacg gaaggacgaa
      601 tattgttgag gttttagaac catgtaaaac aacacagttc tcaaatgtta cggataaacc
      661 gtttgcggga aatcaggttt taaaaccatg taaaacaaca cagttctcaa ataaggcttt
      721 attgaattga tcagtagttt ctgttttaga gttatataaa acgacatggc tcttaaatag
      781 gagctaacga agaaaaagaa ggtactccgt tttggagtta agtagaaata aaaaaataga
      841 atcgttgatt tggcaacgag ttgaaaaata cgcaaaacta tggtcaccaa gggataaccc
      901 tgaaactgat gatcgctata tcttactagt agttaaacag tctaaatagt actcatttat
      961 tgtattgatt ctaagggaac ctgcaataaa tgagtactat tttactttta attccgctat
     1021 ctatgtcatt aggcaactaa attgttatta atatatttac gtttactcgt atatttttag
     1081 taacgcatct gtcaaaactt tagaaaaatt tattttatct ttttcccctc tagctactaa
     1141 ccattctggg actgtgacgt ttttgcgtac ggtctttttt tggataaatg gagaaggatc
     1201 actttgaata agagaaacaa ttttgttatt gcccaaatta tttagttgat gaatatctgt
     1261 tggagaagga actgaaatat cttcatcaat atagtaagct agaatcccat caagaaattc
     1321 tttagcattg gacatagctt cttcaaaatt atctccttgt gttgctccag caaaatcagg
     1381 aaaaactact gagtagccat tttcttcagc agaaaaaatt acagggtaac tttttttcat
     1441 ttccaccact cctttcgagt taatccaatg aactaaagga ctgggctatt tcagccctaa
     1501 gtcctttagt aacttctgct ctgtcccttt ttttaaatcc tgattactat gaacaggaat
     1561 aggaacgggt gggaatcctt ctttggctac aatatgatgg ctgccagtta tcctcaccac
     1621 tttccaacca tttttcttgg ctagtttgag cattttttta ccggtaagtg gcattcgcga
     1681 ctacctcctt acaaatatta ttatacgcat tatgcgtata aaggtcaaga gtttttacat
     1741 taaaagtaga atgtaagtgt cacaataggg tataccctat tgtatcatat ggtaaagtac
     1801 agtataataa ggtttggagg tgtaacacta gggtgtaaca caatgtgaaa tttggaggtc
     1861 attttttgaa caagaaacag gatcaagaat attatataga aaaattggag aaagagaact
     1921 tagaactcaa agagcgaata agatactatg aaaccaaatt ctgtaaaaga ggtgattgta
     1981 tgaaaccaaa tcctgttgaa acaggtaaaa gaattaaatc aattcgttct aattttggaa
     2041 tgactatgga acaatttgca gatttaattg gaaatgctca aaaaggaaat attaataatt
     2101 gggaacgagg attctccctt cccaacaaag aaagattaat taaaattgct gaattaagta
     2161 acaaaactat cgactggatt aaatggggaa ctttagaaga atatataact tcatacctta
     2221 tcggtatagg atatgagcta tatattaaag actttccaga gata
//
LOCUS       DAXLPY010000154         2221 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.162, whole genome shotgun sequence.
ACCESSION   DAXLPY010000154 DAXLPY010000000
VERSION     DAXLPY010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.162"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..377
                     /locus_tag="ACF3UF_002757"
     CDS             <1..377
                     /locus_tag="ACF3UF_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFD3672797.1"
                     /translation="NVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRR
                     FPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDD
                     WQKVMAAEVIATYLDGDLVYKK"
     gene            425..1825
                     /locus_tag="ACF3UF_002758"
     CDS             425..1825
                     /locus_tag="ACF3UF_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFD3672798.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1858..2025
                     /locus_tag="ACF3UF_002759"
     CDS             1858..2025
                     /locus_tag="ACF3UF_002759"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672799.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTGSVAKF"
     gene            2079..>2221
                     /locus_tag="ACF3UF_002760"
     CDS             2079..>2221
                     /locus_tag="ACF3UF_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFD3672800.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVREILYDRGINVSH
                     TTI"
BASE COUNT          627 a          370 c          478 g          746 t
ORIGIN      
        1 aaaatgtttc cacagaggac ttctttaatt attgtcgatt agaggaaagt ggtgtaacag
       61 tcactagcgg tacagattta ccgctgttta ttactgatat tcctgaatcg attataagag
      121 cagtattccg tcgttttcct gaaggagaag aagtctggga gaaagaaaca agcttcacga
      181 caaccgagct gctgaaaagt tttacaagca acagcttcaa agtaaatggt ttatcggagt
      241 acggagaaat aaaagtaggg aaaagcgcca gcttagctgt tttcagcgag gacctctgta
      301 ctgatgactg gcaaaaagtg atggctgcgg aagttatcgc tacctatctt gatggtgact
      361 tagtttacaa gaaataatgc ttttcgatat aacgttataa aacgaattaa agagaggtta
      421 aaaaatggaa acaatgaaaa gaaaattcac cttcccacat agttatacat tgatttttat
      481 cttaattatt ttggctgcaa ttttaacttg gataattcct agtggtcagt ttgagacagt
      541 tgttgaaaac gtcgcaggta tggaaaaaac aacggttgtt ccgggaacct atcaccaaat
      601 cgataaggca gattatggac aaggtttttc ctctatacta atggcaccag ctgaagggat
      661 tatttcagct gttgaggttg ttgcttttgt tctcatcgtt ggtggtgcct tcgggattat
      721 cctaaaaacg ggagccatcg atcgagggct gtttacctta gcaaaagttc tgggagacaa
      781 ggggatctta gttattccga tgtcgatgat tctattcagc ttaggaggat caacctttgg
      841 catgagcgag gaagtcattc ccttatttgc ggtgtttatt tctctgatgt tttctcttgg
      901 ctatgattcc atgactgcga tcttgattct atttttaagt acacaagcgg gatatgttgg
      961 gtcgacgatt aatcccttca acgttttaat cgcacaggga gtagctggcg tttacggaaa
     1021 tcccctgctt tggtttcgga tgctatcctg gattgtcatt actgggattt caattgtttt
     1081 caccatgctt tatgctagca gagtcaaaaa gaatccactg tcctctattg tttatgagag
     1141 tgatttaaag gttaagcata agtttcaaaa ttttgacact gaaaaagagt tttcaacaca
     1201 agataaacta attatcgccg gttttatcgt aggtttagga atcatgattt ggggtatcat
     1261 ttccaaggga tggtatatgg ttgaaatttc tgcactattc ttaggattag gtctttttgc
     1321 tgggggcatc gctagatttt ctcaaaagga aattgctgaa gcttttgtcg aaggctgttc
     1381 agatttcgcc tatgctgctg taatcattgg gctagctaga ggagtcttgg taatcttgga
     1441 aggtggaatg attattgaca ctattctaaa cagcttggct aaccttttag gtggtcttcc
     1501 aaaattcctg ttcactacga ttctactcat ttctcaagta attgtttcct tttttgttcc
     1561 atcctcctca ggagctgcgg cattaacgat gccggttatg gcaccattgg gtgatctaat
     1621 gaatgtaagt cgtgatgttg ttgttctaag taaccagttt ggaaatggtt taatgaatat
     1681 tatctcccca actagtggtg tattactggc aggattagcc atcgcagaga ttaatttctc
     1741 taaatggttt aaggttggct tcaaaatatt tgccatctta acccttgttt ctgctgtttt
     1801 gttatacatt gctacactct tttagtctta atcatccatt aataggaggc aatagttatg
     1861 attaaaataa atcaattagc aggaatgaat atccactatt tattttattc tctcaaagaa
     1921 tttttcgctt atcaacagaa aattggtatt tcttctgttg aactttgggg aggtgctccg
     1981 cattttttca tagatgcttt tactggttct gttgcaaagt tttaaatcta ctatcaaata
     2041 aggtagaata atagaaaaag atagcaggag gaatgacgat gaatcatttt aaaggaaagc
     2101 aatttcagca ggatgtgatt attgtagccg tgggctacta tcttcgttat aaccttagct
     2161 atcgtgaagt tcgagaaatc ttatatgatc gtggcattaa cgtttctcat acgacgattt
     2221 a
//
LOCUS       DAXLPY010000155         2105 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.163, whole genome shotgun sequence.
ACCESSION   DAXLPY010000155 DAXLPY010000000
VERSION     DAXLPY010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.163"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            34..657
                     /locus_tag="ACF3UF_002761"
     CDS             34..657
                     /locus_tag="ACF3UF_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672801.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1107..>2105
                     /gene="trpX"
                     /locus_tag="ACF3UF_002762"
     CDS             1107..>2105
                     /gene="trpX"
                     /locus_tag="ACF3UF_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3672802.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAK"
BASE COUNT          749 a          346 c          446 g          564 t
ORIGIN      
        1 taataaaaaa taggagaaaa agtagaaaag aaggtgtttg ttatttggga agtagttaaa
       61 tcgagagtac aagaaatgaa tgaacatttc tcagtgtcat tcgcagaaaa tccaagtaag
      121 tattttcgac gtcttgtttt tctgctcatc ttatcattgc tgttaacagt tgcaatgttt
      181 ttattgccgg aaaaaatccg agaagagcaa gtaaatagtc tcgtttattc gtccatacca
      241 accagcaaat tgaaaccttt tgattacagc aaagctgatc agaaaatcaa acaaagccgg
      301 gcgatatcgg tgatgttcag caaaccgaac gggaaaacct atcaggacat gcttgatgtt
      361 tttaatgatc ctgagcttat ggaagaattg aatcgaccga tcttttatta tccgatcgtt
      421 tatgatgtac atgaactgga acaaaaatat aacatacgaa cggatgaagt gacatttatt
      481 ttctttgatg gaggaaaaga agcaaatcgg ataactgcgg gtaagggagg aataactgat
      541 tttgataagg agttgatccc tgaactgaat cgacttccgt tagccaatat caaacaatta
      601 gaagaagaat tggatagaac gggagtaact tcccaaaatt ccgagattgc taattgagac
      661 attggcgcga tgaaacggtg ggtctatata gcgctatttt taattatcag aacaagtgat
      721 gtttgatctt caaaataaca aataaaaaat taaaaaatat agttgacgaa attcaaaaat
      781 tcgattagac ttaaatcaat tcttaaggaa agggtgacct gtaatgaact tatcaaaacg
      841 tatttcagca gaaaacaaaa aaaattggcg cagctggcgt agataagttg tattaatggt
      901 gagactttcc catagataca actttttaga gtgcatttct aaagcttgta tctatgctag
      961 acatgaacat tgactgccgc atagattaga atctatgcgg ttttttgtgt aaagacaatg
     1021 accgctttgg ccattgtctt tttttgtaga ctggatactt gcctgattat aataaataaa
     1081 aagattgact ttgcaggagg aaaaaaatga aaaacaaacg attaataaca gttgtagtaa
     1141 ttattttagt ttatttagca ggtgcattta tttatggaaa agcctcaggc gaaaaagaaa
     1201 gtacttcgac gaaccagaca aaaaaaacaa cagttgttgg ggtattgcaa tacgtgagcc
     1261 atccggcatt agatgagatt tatcgaggaa tcaaagatgg tctgaaagaa gaaggattaa
     1321 aagaaggaga aaatcttgag atcaaatttc aaaatggaca agccgatcag agcaagctag
     1381 ccacaatgag tcaacagcta gtacaatctg atccagatgc cttgattgga atcgcaacac
     1441 ctgccgctca atcattagca aacacgactt catcgatccc agttgtgtta ggtgctgtaa
     1501 cggatcctgt gggggctgga ttagtcgctt ctttagagaa acctggtggt aatgtaacag
     1561 gtgtttctga tcagccgcct gttacttcac aaatcaagct tgcttctgat ttgttgccaa
     1621 atgcaaaaaa agtcggaatc ttgtatgctt cttcagagga taattcaaaa taccaagtag
     1681 cacaagcaga agaagctgca aaaaaagaag ggttagaatc agtaaaatat gcggtgcctt
     1741 ccactaatga gattgcacaa acggttcaag tgatgagccg acaagtcgat tttatctatg
     1801 ttccattaga taataccatt gccaatgcga tgcaaacagt ggtaaaagaa gcaaacaaag
     1861 caaatatccc cgtcattcca tctgtggata caatggtgga acaaggtgga ctagcaacaa
     1921 tcgggatcaa tcaatatcaa ttagggcttc aaagcggtaa gatggcggca gaacttgcga
     1981 gtggaaaaga aaaaccggaa acgacgcctg tttatacatt tgatcaaggg gatacagtga
     2041 tcaatcaatc tcaagctgat cgcttaggaa tcattgttcc ccaatcgatg aaggaaaaag
     2101 ccaaa
//
LOCUS       DAXLPY010000156         2100 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.164, whole genome shotgun sequence.
ACCESSION   DAXLPY010000156 DAXLPY010000000
VERSION     DAXLPY010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.164"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            850..>2100
                     /locus_tag="ACF3UF_002763"
     CDS             850..>2100
                     /locus_tag="ACF3UF_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3672803.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          691 a          370 c          369 g          670 t
ORIGIN      
        1 cgaaccgcca caagccacca aataaattcc agaaatctct ccatcatttt tttctacaat
       61 tgcgttaacc gtttttgcta catccatcaa catttcctcc ttaaaatttt aaaaatgtta
      121 attttatcca aaataaaagt aactgattaa atgtaaagat atcacataac gtcatataac
      181 gtcatgtgac ataattgcat tgtatccgct ttctttgtgt ttgtcaatag gaaaaattta
      241 tttctctaaa aaatataaat aatctgcagt gaaacttgag tacatatact aatttcgaaa
      301 aatgcctatg atttaaataa ttatggtgct gggatgaagg tttataagtt tgtcttgatt
      361 tgtttagaag aaatcgtttt tgcacacagt tgaattagga aactactgga gtggaaaata
      421 aagtgatttg acgggtagat gggtgcactt aaatttgaaa atggcttaaa atgctttatt
      481 ttgaattgca gaatttcttt tagtacgcaa tttatggtct taaaactgat taaaaagtga
      541 tacattgatt ttaatacaat ttatgataca aaaaatgacc tcctttctta aataaaagag
      601 gtcattttgt tttgtctcat aatcgattgt ttttgataca gtagttatat tcagaaaaaa
      661 taaagactct tctgagttta taatcctttg gattatatac ggatacagat gtagacataa
      721 aacaagctca attttcaaaa atggcattac tcaccttttt ggtgaattat ttgtataaaa
      781 aaaatataga aaagacaccc tgaaatcctt tagaattaat ttggctacca attcatagga
      841 ggattcaaga tgtctcatac tcagcttatc aaagataccc taaatattct agacctaaat
      901 atctatttcg aggaaaattg tttaactaaa gaaaaataca aagggcaaat ttgcttgatt
      961 tacaaaggaa ctcttctgta caagccagaa gagtgttccc attgtctttg tgtcgtcccc
     1021 tctaggatca ttcgttgggg gacgacaacc gttcggttgt tactgaatga tgtgtctgag
     1081 tatcgcactt atctggagct gaagaaacaa cgatttaaat gtaagtcttg ccaaagaaca
     1141 ttcgtagcgg atacctctgt tgctgaaaaa cactgtttca ttagtcaaaa agttcgttgg
     1201 tctgtcattg ctcgcttaaa agagaatact tccatgacgg aaatcgctcg tcagaaaaat
     1261 atttccactt cttcggtcta tcgtgtcatg aagcgattct accgcccatt gaatcctttc
     1321 aaacagactt tgccaaaggt cttatgcttt gatgaattca aatcggttcg aagtgttgcc
     1381 agtgcaatga gttttatcat gatggacgga caaagccatg cattattgga tattgtcgaa
     1441 aatcgacgct tgccttattt agaacgctat ttttctcggt tttcattagc gactcgtgaa
     1501 gccgttcaat tgattgttat tgatatgtat gcgccttatg tttcgttggt gaaaaagctt
     1561 ttcccgaatg ctcagttgat catcgatcgt ttccacatcg tccaacatat tggcagaact
     1621 ttcttgaatc atcgagtgaa agaaaccacg gtacgactta aaggaaattc ccactctcaa
     1681 cgagggttag ggaaaaaatt gaagcgctat tggaaactcc tacaaaaaga agaagcaaag
     1741 ttaaactatg aaaaacgggt ttggcgtgcc agttttaaag attatttgac tgaaagtgag
     1801 attgccgatc gactgttagc tgcttgtccc aacttacgcc aaggctatca gttataccaa
     1861 gacattcttt atgcggtaaa gaaaagagat cagtcactat ttgaggattg tttaactaga
     1921 gacattagcg gtctgccaga aacctataca accactttac gaacgtttaa aaagtttctg
     1981 ccacagatcc aaaatgcgct tcactacagc tattcaaacg gaccattgga atgcttaaac
     2041 aaccacatca aagtattaaa acgcaatgcg tacggctttc gcaactttta caatttcaaa
//
LOCUS       DAXLPY010000157         2071 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.165, whole genome shotgun sequence.
ACCESSION   DAXLPY010000157 DAXLPY010000000
VERSION     DAXLPY010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2071
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.165"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            127..1305
                     /locus_tag="ACF3UF_002764"
     CDS             127..1305
                     /locus_tag="ACF3UF_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3672804.1"
                     /translation="MENMSRFKKHITATGKITWYFQAFRTTRRGFNSKREAQLAYLEM
                     EKQHRNKQKRIASNDKFNVVSQKWFEYYRSLNEQKRATYDKREEQVKILNRWIGDKKL
                     SSLSSEELQKFLFILKEKGIDGIDVGYAKNSLQSLVQVLNMIFKYCKKKNLINENPME
                     FVKMPKYQLTVEDLKESVNSLEDKFLTVDELRTFLNYGIIYEELPMSVLFHVLFYTGC
                     RVSEALALQPQDIDFERNEILFYKQTAVKGKSKDFRIETTKSVSSARRVPVTPLVMEK
                     LHELIDVLNKTKRNSNFVVDETYLFVYLDPGKRGVPYRREYVNDHVKRCVERCGINKN
                     FHTHLARHTMASLVAEYCSWDVLKDRLGHTDSTTSKIYRHLTSNERIKPLLAFDSLEN
                     "
     gene            complement(1484..1669)
                     /locus_tag="ACF3UF_002765"
     CDS             complement(1484..1669)
                     /locus_tag="ACF3UF_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672805.1"
                     /translation="MLEYSGFFIKAVTLKKDIIIVLFFLLLLIGRFILIHYSPLPIIK
                     EKTGSGCSNYMLRKKNP"
     gene            1706..1999
                     /locus_tag="ACF3UF_002766"
     CDS             1706..1999
                     /locus_tag="ACF3UF_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFD3672806.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT          757 a          259 c          388 g          667 t
ORIGIN      
        1 tttcgtttat tacgagaatt gtagaattta ttttttcgtc tgtatattgt ataattattt
       61 tataaataga aagattttca agagtttccg attgttgggt tccttcataa ttgggggtaa
      121 aaacaaatgg aaaatatgag tcgttttaaa aaacatatta ctgcaacagg aaaaattact
      181 tggtactttc aggcttttcg aactacgaga cgaggtttta attctaagcg tgaggctcag
      241 ctagcttatc ttgaaatgga aaaacaacac agaaataagc aaaaaagaat tgctagtaat
      301 gataaattca atgtggttag tcaaaagtgg tttgaatatt atcgatcact aaacgaacaa
      361 aagagggcaa catatgataa gcgagaagaa caggtaaaaa tacttaatcg atggattggt
      421 gataaaaaat taagcagttt atcttcagaa gaactacaaa aattcctttt tattttaaaa
      481 gaaaaaggaa ttgacggcat tgatgttggt tatgctaaaa atagtttaca atctcttgtt
      541 caagttctaa atatgatttt taaatattgt aagaaaaaga atttgataaa tgaaaatcca
      601 atggagtttg taaaaatgcc taagtatcag ttaacagttg aagatttaaa agagtctgtt
      661 aatagtttag aagataagtt tttaacagta gatgaattgc gaactttttt aaattatggg
      721 atcatttatg aagaattacc catgtctgtt ctttttcatg ttttgtttta tactgggtgt
      781 cgtgtgagtg aagcacttgc tttacaacct caagatatag attttgaacg aaatgaaatc
      841 ttattttata agcagacggc agtaaaagga aaaagcaaag attttcgaat tgaaactaca
      901 aaatctgtta gttctgctag aagagtacct gtcacaccgt tagtaatgga gaaattgcac
      961 gaattaattg atgtattaaa taaaacaaaa agaaatagca attttgttgt agacgagact
     1021 tatttatttg tttatcttga tcctggtaag cgtggagttc cttatcgtcg tgaatatgta
     1081 aatgaccacg ttaagcgctg tgtagagaga tgtggaatca acaaaaattt ccatactcat
     1141 ctggctcgtc atacgatggc tagtttagta gctgagtatt gcagttggga tgttttaaag
     1201 gatcgtttag gtcatacaga tagtacaact tcaaaaatat atcggcattt aacatcaaac
     1261 gaaagaataa agcctttgct tgcttttgat tcattagaaa attagatttt ggcagaagtg
     1321 caggtatttt agaatctaaa ataggtgttg tgactatgct ttagtcaaag tgtagtcaga
     1381 aaaagagaaa aacttttata tcaatacttt aatgactttt cacaagtatc aaagaaatcc
     1441 gtcgttaatc attgttatca gactgagaaa gaacccttgg tattcaaggg ttcttttttc
     1501 ttagcatgta atttgaacac cctgatccag ttttttcttt aattattggt aggggagaat
     1561 aatggattag aataaatcta cctataagta gtagtaaaaa aaagagcact atgataatat
     1621 ctttcttaag agtaaccgct ttaataaaaa atccagaata ttctaacata aatggagtat
     1681 tcttagaatc aaaaggagaa agaagatggt ttatacttat acggagcaag aaaagatgaa
     1741 agttttagac acattcatga atgatggaaa agtaaaacaa gtaccaagtt caacaaaaaa
     1801 gaaatacatc ctattgaaag aagtcttgaa acgctttgac catggagtga cttatacaga
     1861 aacagaggtt aattcgatac tgctgaacgt attttctagt ggcgattatg tcgaacaaag
     1921 acgttatcta atcacatttg gctttttcaa aagaagttca gacggtcggg catatcagat
     1981 gatgggaatt gaaaattaga agttttaatt tatactcatt gaaaaaagtt caagtatgcg
     2041 atattggttc tacaccgcat acttgaactt t
//
LOCUS       DAXLPY010000158         2068 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.166, whole genome shotgun sequence.
ACCESSION   DAXLPY010000158 DAXLPY010000000
VERSION     DAXLPY010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.166"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..658
                     /locus_tag="ACF3UF_002767"
     CDS             <1..658
                     /locus_tag="ACF3UF_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672807.1"
                     /translation="QFLEELSGEEYRLFLNNNILKLISYAKKANSLSLVDNLDNLLPD
                     KLIYDENEDNSQKQIIIFELYLKWLSSLSVSPESNDDDKYFANKLFQFIFPDYSSMPF
                     FTLINFMLYVKEHLGYDDLVEMIKAYDKEPYPFKGINTGSDMAMISGETVEEILANYK
                     EQNIKTLELIKKNIKYYDPLLANKENIDKLLNAIADSDVRSPRIDELKEEILMYKELF
                     "
     gene            complement(655..1278)
                     /locus_tag="ACF3UF_002768"
     CDS             complement(655..1278)
                     /locus_tag="ACF3UF_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672808.1"
                     /translation="MKIAYIRVSSIDQNEQRQIEEMKKFGAEKIFIEKQSGATITHRP
                     IFQEALEFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PHLDKFIKDLIIQILAMIAEQERTESKRRQAQVIKIAKANGVYKGRPKLYSADTKNPQ
                     RRLVYENIVKDLNEGIAISKIAKNYNITRQTIYRIKNDIEYNSNQMN"
     gene            1554..1934
                     /locus_tag="ACF3UF_002769"
                     /pseudo
     CDS             1554..1934
                     /locus_tag="ACF3UF_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            1934..2068
                     /locus_tag="ACF3UF_002770"
                     /pseudo
     CDS             1934..2068
                     /locus_tag="ACF3UF_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
BASE COUNT          746 a          306 c          336 g          680 t
ORIGIN      
        1 acaattttta gaagaattat ctggagaaga atatagatta ttcctaaata ataatatttt
       61 aaaattaata tcttatgcca agaaagctaa tagcctatct ttagtagata acttagataa
      121 tcttttaccc gataaactta tttatgatga gaatgaagat aattcacaaa aacaaataat
      181 tatatttgaa ttgtatttaa agtggcttag cagcctgtca gtgtcaccag aaagcaatga
      241 tgatgataaa tattttgcga acaaactgtt tcaatttata tttccagact attcttcaat
      301 gccatttttt acattaataa attttatgct gtatgttaaa gaacacttag gatatgatga
      361 tttagtagaa atgataaagg catatgataa agaaccttat ccattcaaag gaatcaatac
      421 tggttcagat atggctatga tttcaggcga aactgtagaa gaaattctag ctaattacaa
      481 agaacaaaat ataaaaactc tggaattaat taaaaagaat ataaaatact atgatccttt
      541 actagcgaat aaagaaaata ttgataagtt attaaatgca attgctgatt ctgatgttag
      601 atctcctaga attgatgagt taaaagaaga aattttaatg tataaagaac ttttttaatt
      661 catttgatta ctgttatact caatatcatt cttaattctg taaatagttt gtctagtaat
      721 attgtagttt ttagcaattt ttgaaatagc tatgccctca tttaaatcct taacgatgtt
      781 ttcataaact aaacgtcgtt gaggattttt tgtatctgca ctatagagtt ttggacgacc
      841 tttatagacg ccatttgctt ttgcaatttt aatgacttgc gcctggcgtc gtttagattc
      901 ggtacgctct tgctctgcaa tcatggccaa aatttggatg attaaatctt taatgaattt
      961 atccaaatga ggattgccaa ttgcttcagc catgatcggt agactggtga tgatcagctg
     1021 cacgtttttc ttctttaggt aattgactga agcaatgatt tcgtcgtaat ttcttccaag
     1081 tcggtcgatt gcttcgacaa taaaaatatc ttggtctcgg acaaactcta aagcttcctg
     1141 gaaaatcggt cgatgagtaa tcgttgctcc agattgtttc tcgatgaaaa ttttttctgc
     1201 gccgaacttt ttcatttctt caatttggcg ttgctcattt tgatcaatcg acgaaactcg
     1261 aatataagca attttcaaaa tttttaccta cttcctcaaa ctatttaaaa tacactcaaa
     1321 atcaacacta atttttttat acactataaa gctgtcattt ttctagataa atggcataaa
     1381 ttttcagcgc taagtgacaa aagcaactaa tttttcatga tagattttta aatatctcaa
     1441 tctatctcca aaattagttg cttttgtagc tatagttgac tatgaatatg acaaataatt
     1501 agaaaaaact gtgccaatta aatatcaaaa tgacaaattg atgaatcaaa ttcaaattaa
     1561 ggggggcaac cctggaagtc ttaaatttac cctcaatgaa tggtattgaa gatgaaaatt
     1621 taaggcgttt gattaatagc cttgtcattg aattgtacaa gtatcaagca gaatcagaac
     1681 gaaaaaaaat taaggaacgt caggcacaag gaatcgaaat tgctaagaaa aaaggcaaat
     1741 tcaaaggtcg gcaactgaaa tttaaaaaaa atgatccacg tttaaagcat gctttcgatt
     1801 tgtttttgaa tggtttatcc gataaagaag ttgaagaaca aactgggatc aatcgccgaa
     1861 cgtttagaag gtatcgagca agatataacg tgacagtaga tcaaagaaaa aacaatgaaa
     1921 agagggatag ttaatgagta cggttatttt agctgaaaaa caagccaggc attagcctac
     1981 gcaagtgctt taaaacaaag caccaaaaaa gacggttatt ttgagatcaa agacccacta
     2041 tttacagatg aaacgtttat cacctttg
//
LOCUS       DAXLPY010000159         2027 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.167, whole genome shotgun sequence.
ACCESSION   DAXLPY010000159 DAXLPY010000000
VERSION     DAXLPY010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.167"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..582
                     /gene="mobL"
                     /locus_tag="ACF3UF_002771"
     CDS             <1..582
                     /gene="mobL"
                     /locus_tag="ACF3UF_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HFD3672809.1"
                     /translation="MNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVL
                     TKEPEYQEYIQISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQD
                     SQIKPLIESVDQMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLR
                     QLNRTINAHEEKYHASKAYEEQQRRIQMEQERQ"
     gene            603..923
                     /locus_tag="ACF3UF_002772"
                     /pseudo
     CDS             603..923
                     /locus_tag="ACF3UF_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1084..>2027)
                     /locus_tag="ACF3UF_002773"
     CDS             complement(1084..>2027)
                     /locus_tag="ACF3UF_002773"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3672810.1"
                     /translation="GPHAGGKHYPKKGFNHIRSKVKMSDVFEFIQSNVHDHDVKQMCT
                     VLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHKILVGRGETL
                     SLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSINQKWVTDITY
                     IHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTPSENLIIHSD
                     LGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYPSKAYENFEA
                     AYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
BASE COUNT          667 a          352 c          423 g          585 t
ORIGIN      
        1 atgaacttat taaatgaagt atataaaacc ctacctgaca aacgttcgga atggaattac
       61 ggggatgaaa aacgaaccaa actttcacca tacacaagag agaaactcga tgagttaacc
      121 aaatatgttt taacaaaaga acctgaatat caagaatata tacagatttc aaaagcattg
      181 aaagaagaag caaaaagtct ttatggggaa agcaagagag aatcaaagga tgcagagaaa
      241 aatgctctct ttgatttaaa aaagcgcaca ggaaatgcca tcctaacaga gctgaagaga
      301 caggatagtc aaataaaacc attaatagaa agtgttgatc agatgcaatc tatttacaat
      361 gaacgatcct ttcgaacgct taaacaattg ccaacgaatg aatacaaata tagttacgaa
      421 gaattcatga agcgcaggaa acaattccaa caaagagttg tcacgcagcg gagtttgcgt
      481 caattaaatc gaacgattaa tgcccatgaa gaaaaatacc acgcaagtaa agcatacgaa
      541 gagcaacaac gaagaattca aatggaacaa gaaagacagt aaagacagta ggaggaatag
      601 caatgaaaca atatttagat caatggaaag ttatagaagg atcattaaga gaagaacgaa
      661 tcgaacaact tcctgattgt ttagaaaaag agcatttgtt ccagataaga gaaatgttga
      721 gaaacgaaca gtttgatcca aatcaatttt tagtcgttga gtacccagct actggtgtgt
      781 attgttgtaa tcatgtgaat ggtgaaaaat attttatcat tcaagaatat gagggcaagt
      841 tagcacctta ttatactact tgggaaatga atgaagaggg aatcaataac tttccatgta
      901 aaagcattgg atttgagtca atacctcgga cacgatttgt gagaattttt tcgagattcc
      961 agcgggtgag tatctcatcg tttcgaccag cggtcaaacc aaaaccgttt gaccgctgat
     1021 cgaagcgatg aagttgaaac cctgtggaaa tctcgccaaa aaaatgtaag tggtagctag
     1081 gaactaagct tgcaatgcca actcctccat ctgatttggt gttaaatagt tgatactact
     1141 atggattcgc ttgcgattgt aaaatccttc aatgtattga aataacgcta aataagcagc
     1201 ttcaaagttt tcatacgctt ttgatggata gacttcttct tttttgagtg aggcgtgaaa
     1261 cgattcgata ccggcattat cgtagggaca gcccttacga ctgaaggagt gccgaatgtt
     1321 caattcattc agctttgcct cataggcttc gctagtgtac tgagaaccca aatctgagtg
     1381 gatgatcaag ttctcggagg gtgtttggtt taagagcgca ttgtcaaggg tttcgataac
     1441 caattctttc gtcatctgct tgccaaactt ccaaccgatg actttctttg tgtggaggtc
     1501 ttgaatagtg gagaggtagg tccagccatc ttttagggta tgaatatagg taatatctgt
     1561 cacccatttt tgattgatcg acgtagtggt aaaatcttgg tttaacaggt ttttacgtcc
     1621 ttcactttta actttcgctt gtttgccagg cttgtacttc ttgagggtga ctgaacgcaa
     1681 gcctaatttt ctcatcagta tttgtacttt ctttaaggac aaggtctcgc cacggccaac
     1741 aagaatctta tgaattttag gcgcaccata gatacccttg ttttcaaagt agattcctga
     1801 aatcaagcgg tttaagcgtt tgttttctga ttggcgcttg gaaggtttct ttttcttcca
     1861 gtcatagtag ctggatttcg gtgcttccaa aacggtacac atttgtttta cgtcatgatc
     1921 atgaacattt gattgaataa attcgaagac atcactcatt tttacttttg agcgaatatg
     1981 gttaaagcct tttttaggat agtgttttcc tcctgcatgc gggccat
//
LOCUS       DAXLPY010000160         2021 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.168, whole genome shotgun sequence.
ACCESSION   DAXLPY010000160 DAXLPY010000000
VERSION     DAXLPY010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.168"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            101..571
                     /locus_tag="ACF3UF_002774"
     CDS             101..571
                     /locus_tag="ACF3UF_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFD3672811.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            793..1896
                     /locus_tag="ACF3UF_002775"
     CDS             793..1896
                     /locus_tag="ACF3UF_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFD3672812.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          687 a          328 c          460 g          546 t
ORIGIN      
        1 agaatctctg aagaataaat cacgtgatcg tgacgataaa atacacttac gtcaggtgat
       61 aaaaaataca taagtagaaa actaagagga ggaacagaaa atgaaagaag ttcaattgat
      121 cagaaaaagc gaactatcag aaggtggttg caatgcatgc ggcgtagtag aagcaacaag
      181 ctatacatta aagcttggtg ccaacaaagc gataatctct gagttgacag taggcggtct
      241 tgtggacagt ctggcgcttg ctgaaggttt tattggagaa gatatttatg agatgttttc
      301 agaaatccgt cagttaaaaa aaggggaaaa ctgcatagag gttcatcatg agagcccgaa
      361 tgtgagattc aaacgtggtg ataatgagat gatcttcaat aatcatgtgt ccgatcacac
      421 cgagctatat ggaatcgtga atcaaatact aactgagctt tttggattgg gaccttatgc
      481 gttcaaggaa gaaaacggta atccaaaatt aaacgaagaa tggcaagaaa cgattgaaat
      541 acaaagaaac aacccgcact tatttcaata ggcatccaca gtatttcgta aaagggactt
      601 tgacacgact tttgtcaaaa tcccatcgtt ttttatctat ttgtgttcta aacatttctt
      661 tcagagtagt aacaactgga atgactgaaa tgtaaacaga ttatttgcct gtatcaatac
      721 ggaagagtaa tataaagtgt gtaaacgcta tcatattatt cattcaattt tttatagagg
      781 gaaggcattg aaatggaaaa aacgtatcaa gcaggtacaa atgaaggaat agtggatttt
      841 atcaatatgg aagatttaga aatagccgct tcacaagtga ttccagctgg tggttatggt
      901 tacatcagca gtggtgctgg cgacttattt acttatcaag aaaatgaacg ggcattcaat
      961 catcagctga ttattcctca tgtattaaga gatgtagaat tacccgatac aactacacat
     1021 tttgacaaag aaacgctgac tgcaccaatc atcatggcac cagttgctgc tcatggctta
     1081 gctcatgtga aggcggagaa agcttctgca aaaggtgtag cagattttgg gacgatctat
     1141 acagcaagtt cttacgcttc ttgtacatta gaagagataa gagaagcagg cggggagaaa
     1201 gcaccgcaat ggtttcaatt ttatatgagc aaagatgatg ggatcaattt ggatattctt
     1261 gaagtggcca agcgtaatgg agcaaaagca atcgtattga cagcggatgc aacagttggc
     1321 ggaaaccgtg aaacagaccg cagaaatggg tttaccttcc cactgccaat gccgatcgtt
     1381 caggcttatc aatcaggagt aggccaaacg atggatgctg tgtacaaatc ttccaaacag
     1441 aagcttagtc caaaagatgt agaatttatt gctgctcatt ctgatttgcc agtctatgtg
     1501 aaaggtgtcc agtcagaaga agatgtctat cgttcattag aatctggtgc tggcggaatc
     1561 tgggtatcta atcatggtgg ccgtcaacta gatggtggtc cagcagcgtt tgattcgttg
     1621 caatatgtgg cagaagcagt agataaacgt gtaccaatcg tgtttgacag cggtgtacga
     1681 cgcggacagc atgttttcaa agcaatcgca tcaggtgcag atcttgttgc tattggcaga
     1741 cccgttattt atggattgtc tttaggagga agtacaggag tccatcaagt gtttgatttc
     1801 tttaaaacag aattggaaat ggtcatgcaa ttagctggaa cacaaacagt agaagatatc
     1861 aaaaaaataa aattgcgtga gaatcgtttt atttaagaaa caaatgacga aaaaaatagg
     1921 agtgcggcag atgatgccgt actcctattt ttatagttca aggatgtcac taatagaata
     1981 atttgaaacg aaaaaataaa attgaaatat tttttcatac t
//
LOCUS       DAXLPY010000161         1980 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.169, whole genome shotgun sequence.
ACCESSION   DAXLPY010000161 DAXLPY010000000
VERSION     DAXLPY010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.169"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..367
                     /locus_tag="ACF3UF_002776"
     CDS             <1..367
                     /locus_tag="ACF3UF_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFD3672813.1"
                     /translation="KKQIVPKEIETWWRIEMQLRRGKATDWHAMVRESLDSFASPHYL
                     PGDVKPVDRIMIKGLNQDHSEWAYISRNLKYRLRKLLKEESQNDELTNHLRETFKESA
                     NDLKIELDTWLLGLDVTEK"
     gene            1331..>1980
                     /locus_tag="ACF3UF_002777"
     CDS             1331..>1980
                     /locus_tag="ACF3UF_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3672814.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVDDK
                     VHPLKLSWSIDRITIVGKLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQ
                     LFDQYGEDIAYIEMLKFHPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAHFSRADIA
                     CDILGVPDDFITQYRIVDPVSFKPIYGRSGKLETAYWGSRASERQVRMYNKKLEQER"
BASE COUNT          657 a          305 c          461 g          557 t
ORIGIN      
        1 aaaaaaacag attgtaccaa aagaaatcga aacatggtgg cgtatagaaa tgcagctaag
       61 acgtggcaaa gcaacagatt ggcatgcgat ggttcgggaa agtttagata gctttgcaag
      121 tcctcattac ttgcctggag atgtaaaacc tgttgataga attatgataa aagggctgaa
      181 tcaagatcat tcagagtggg cgtatattag cagaaatttg aaatatagat tgcgcaaatt
      241 gttgaaagaa gaaagccaaa acgatgagtt gacgaatcat ttacgagaga cgtttaagga
      301 atctgcaaac gacttgaaaa tagaattaga cacgtggctt ttgggtttgg acgtgacaga
      361 gaagtgatac cgaataagaa aagtcagatg agtgagagta aatttacgtc aatgtttaat
      421 gacgtgagtt tacgataagc gattattttg cgtgaagcaa aataaagcgt aaaaggagtt
      481 gagagcgtga cacgctttcg gctccttttt tcgttgtcac ttgtgacagc gaataccctc
      541 ggagagcatt tggaattgtg acagccatgt cacaattagg aaaatgttta ctctttgtca
      601 aagagtaaca gaaaggttta cactcttttt attagcgaca gcgcgaagga ggggtttaac
      661 ttggggttta gtatttcgtt caaaaaggga acaaagaata caagcatttc tcataataat
      721 cgtgagttaa ctgatagcca aaaaatcaat ggtttgtctg gtagaaaata attagcagat
      781 ttacaagtgg gaaataaaaa gctgaaagaa gaaaattgca tttcaaacta cattttctac
      841 aatagctcta aaatggcata ttttgcgttc tgagcggttt tagcgtttat ttcgtttagt
      901 tatcggcaca atcgttaaaa cacgttagag gagcgaaaat ggagcctgta aggcgactgg
      961 tagcggaacg atcgtgttag attgtgaaaa ccgatagctg aatgaaataa acagcgggtg
     1021 cgccctttcc atttcggcag gaggaggctc aaggggttcg gggaatgaaa ttccctgagg
     1081 tctttttatt tttttaggag gagtgctata atcaaagaaa acgagaaaaa agagcaaaat
     1141 aaaagccgag cagtgcgcta acactctcga ctatttacgg aaactacttc acctagctcc
     1201 gtaactcagg ttcattatac gaatattttt aggtttcttc aagctagaga tttttggata
     1261 tgaattttta gggttacgtg aactctggaa attctttcca aaagtctctt ttttcgtctg
     1321 gaggacgaaa atggcaaatg aaaatcagtt gagtgaaatt caatcaaaaa ttgaaggtcg
     1381 aggggcagaa aaaagaacaa cgataaatca gctcgaaaaa cttaaccgta tttctaacag
     1441 gcggttaagt gttgacgata aggtacaccc cctaaaatta agttggtcaa tcgatcgaat
     1501 tacaatcgtc ggaaaactga atgataccat agcttattgg acgcaaaatg gagttgtgtt
     1561 tgtcgatttt gagcaattaa tgcgtttgaa tgaaaatcaa gggtatttga agtcggttgg
     1621 tacaaatggt tggcaattat ttgaccaata tggagaagat atcgcctata tcgaaatgtt
     1681 aaaatttcac cctgacaaag gtcgtattga ttttaatcca aataaaattg gcgagttttt
     1741 aaaggggtcg atgaaacaat tcattcatga tttgtttctg gatgcgcatt tctcacgtgc
     1801 agatattgct tgcgatattc tcggtgttcc tgatgatttt attacccagt atcgaatcgt
     1861 tgaccctgtg tcttttaagc caatttatgg ccgttctggc aaattagaaa cagcgtactg
     1921 gggtagtcgt gccagcgagc gacaagtgcg gatgtacaac aaaaagcttg aacaggaacg
//
LOCUS       DAXLPY010000162         1971 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.170, whole genome shotgun sequence.
ACCESSION   DAXLPY010000162 DAXLPY010000000
VERSION     DAXLPY010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1971
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.170"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            192..425
                     /locus_tag="ACF3UF_002778"
     CDS             192..425
                     /locus_tag="ACF3UF_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HFD3672815.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            422..829
                     /locus_tag="ACF3UF_002779"
     CDS             422..829
                     /locus_tag="ACF3UF_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFD3672816.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(1280..1789)
                     /locus_tag="ACF3UF_002780"
     CDS             complement(1280..1789)
                     /locus_tag="ACF3UF_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672817.1"
                     /translation="MKKVLFAVSLVVNIALAGGLFYTITEMNKLDDQRESLAISNEQY
                     KRKLDEASSTNVDTQEAVESSTIVYSNESSETLTNSERSTAPATETVSQKATITIGSK
                     VFTFIVNGLTIEHDSSRTGKMTELSHEFPVIVTTPSATLNGILVQDNNDNNCYIMVDG
                     QTLYRGTYQ"
BASE COUNT          680 a          301 c          326 g          664 t
ORIGIN      
        1 aatttaaaat aaatggtata cataaatagg gaaggaaata gaagggagca atctaaattt
       61 tttgaatttt cttaattaat tatatagaaa gaacaatctt tctatagagt tagacatgag
      121 agggactatg cttgatttaa aatcaacaag cgtatatact gtatatacaa agaaaaagga
      181 gggagaagac tatggcaatt aaagaaagaa aatttaggga agtggggaac tcagtagtat
      241 taactatttc aaaggagttt cttaaagaaa atgggttaaa tcccggagat acggtttttt
      301 tagatgaaga aaaacttcga gcggcaatta caaaaaaaca agccttatct gatgaaattg
      361 atttagcaat atctcaagca ttaactgaat atgatactac ttttagagag cttgtcgata
      421 aatgagtatt cattacctag aagccaaaga tattataaaa atgaatgtaa tccaaataaa
      481 aaaatactct cctaatgaac cccttggtgt aaaggatgcg aatgctttag aaatgtgtgt
      541 agggcaactt cgagcctcag cttttggtga agaggtttat ccttcgattt atgaaaaagc
      601 agctatccta cttatacaat tgataaagaa acatcctttt cacaatgcaa ataaacgtac
      661 tgctttctta gctacttttg tctttttgaa aatcaatgga cagcttttag ctattgatca
      721 aaaagatgct gtaaatttag cggtatatat tgctacgtat gataaggatt tcgatcaact
      781 aaaatatgaa gtgatcaaca ctataaagac acatacgcag cccatttaag gagttactgt
      841 atgtgtcttt atagggttat tagctgctat agcgaaataa ttgaagtaaa ttacaaatag
      901 ctataattca aatccaacta tatagaaaac gtaaattttc tatatacttg gatatgctgg
      961 aatgtttaag agaataatta catttctaga aaatacaata aaaattacag gataattagc
     1021 catatcctac ctcctctagc agttgctcaa aagttagcac taagtaactt cttttttgtt
     1081 gctggtaaca atttatcaat actaaaatag cgtttaagta tctaataaat actaatttta
     1141 aagctcttaa ttattatgaa acacgatata acaatattgc tatatcgtgc tattgtaata
     1201 ttatacattt gaagacagcg tattcttgtt ctaatatcag gaatttttta taaatatcag
     1261 tcatattaag actcaaaatt tattggtatg ttcctctgta tagagtttga ccgtctacca
     1321 ttatatagca attattatca ttgttgtctt gcaccaatat accgttaagg gtagcactag
     1381 gagtagtaac aatcactgga aactcatgag aaagctcggt catttttcct gttctgctag
     1441 aatcgtgttc tattgtcaag ccatttacta taaacgtgaa tactttactt cctattgtta
     1501 tagtagcttt ttgagaaaca gtttctgtag ctggagctgt gcttctttcc gaatttgtta
     1561 gggtttcact ggattcattg ctataaacaa ttgtagagga ttctacggct tcttgagtgt
     1621 ccacgttggt gctgctagct tcatctagct tccttttgta ttgttcgtta ctgattgcta
     1681 agctttcccg ttggtcatca agcttattca tttctgtaat ggtataaaat aatcctcctg
     1741 ctagtgctat attaacaact aaactaaccg caaataatac ctttttcatt cttccttctc
     1801 ttctttctct ttttgtaatt ccttactttt ggataggcta caattaacta gacagaaaaa
     1861 ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct aagagaacac
     1921 gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta g
//
LOCUS       DAXLPY010000163         1914 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.171, whole genome shotgun sequence.
ACCESSION   DAXLPY010000163 DAXLPY010000000
VERSION     DAXLPY010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.171"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            4..396
                     /locus_tag="ACF3UF_002781"
     CDS             4..396
                     /locus_tag="ACF3UF_002781"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3672818.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDDIVYVYDYEKGDK"
     gene            397..1836
                     /locus_tag="ACF3UF_002782"
                     /note="aph(2'')-Ia"
     CDS             397..1836
                     /locus_tag="ACF3UF_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFD3672819.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTDKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCSHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          803 a          138 c          326 g          647 t
ORIGIN      
        1 tttatggaag aagttttaat tgatgataat atggtttttg atattgataa tttaaaagga
       61 tttcttaatg ataccagttc atttgggttt atagctaaag aaaataataa aattatagga
      121 tttgcatatt gctatacact tttaagacct gatggaaaaa caatgtttta tttacactca
      181 ataggaatgt tacctaacta tcaagacaaa ggttatggtt caaaattatt atcttttatt
      241 aaggaatatt ctaaagagat tggttgttct gaaatgtttt taataactga taaaggtaat
      301 cctagagctt gccatgtata tgaaaaatta ggtggtaaaa atgattataa agatgatata
      361 gtatatgtat atgattatga aaaaggtgat aaataaatga atatagttga aaatgaaata
      421 tgtataagaa ctttaataga tgatgatttt cctttgatgt taaaatggtt aactgatgaa
      481 agagtattag aattttatga tggtagagat aaaaaatata cattagaatc attaaaaaaa
      541 cattatacag agccttggga agatgaagtt tttagagtaa ttattgaata taacaatgtt
      601 cctattggat atggacaaat atataaaatg tatgatgagt tatatactga ttatcattat
      661 ccaaaaactg atgagatagt ctatggtatg gatcaattta taggagagcc aaattattgg
      721 agtaaaggaa ttggtacaag atatattaaa ttgatttttg aatttttgaa aaaagaaaga
      781 aatgctaatg cagttatttt agaccctcat aaaaataatc caagagcaat aagggcatac
      841 caaaaatctg gttttagaat tattgaagat ttgccagaac atgaattaca cgagggcaaa
      901 aaagaagatt gttatttaat ggaatataga tatgatgata atgccacaaa tgttaaggca
      961 atgaaatatt taattgagca ttactttgat aatttcaaag tagatagtat tgaaataatc
     1021 ggtagtggtt atgatagtgt ggcatattta gttaataatg aatacatttt taaaacaaaa
     1081 tttagtactg ataagaaaaa aggttatgca aaagaaaaag caatatataa ttttttaaat
     1141 acaaatttag aaactaatgt aaaaattcct aatattgaat attcgtatat tagtgatgaa
     1201 ttatctatac taggttataa agaaattaaa ggaacttttt taacaccaga aatttattct
     1261 actatgtcag aagaagaaca aaatttgtta aaacgagata ttgccagttt tttaagacaa
     1321 atgcacggtt tagattatac agatattagt gaatgtacta ttgataataa acaaaatgta
     1381 ttagaagagt atatattgtt gcgtgaaact atttataatg atttaactga tatagaaaaa
     1441 gattatatag aaagttttat ggaaagacta aatgcaacaa cagtttttga gggtaaaaag
     1501 tgtttatgcc ataatgattt tagttgtagt catctattgt tagatggcaa taatagatta
     1561 actggaataa ttgattttgg agattctgga attatagatg aatattgtga ttttatatac
     1621 ttacttgaag atagtgaaga agaaatagga acaaattttg gagaagatat attaagaatg
     1681 tatggaaata tagatattga gaaagcaaaa gaatatcaag atatagttga agaatattat
     1741 cctattgaaa ctattgttta tggaattaaa aatattaaac aggaatttat cgaaaatggt
     1801 agaaaagaaa tttataaaag gacttataaa gattgattat ataatatatg aaaagctatt
     1861 ataaaagaca ttagtattaa atagtttaaa aaaatgaaaa ataataaagg aagt
//
LOCUS       DAXLPY010000164         1876 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.172, whole genome shotgun sequence.
ACCESSION   DAXLPY010000164 DAXLPY010000000
VERSION     DAXLPY010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.172"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            239..919
                     /locus_tag="ACF3UF_002783"
                     /pseudo
     CDS             239..919
                     /locus_tag="ACF3UF_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
BASE COUNT          677 a          257 c          315 g          627 t
ORIGIN      
        1 tttaaacggt agttacttag ttcttctttg atttgcgtga aatagagggg atttattttt
       61 ctggttacgt gattaaaaaa tccaaaaaat gagcatagga acggttatga ttttagggtg
      121 tgttttaatg agatattgtg atttcattaa caagtgtatg ataatcggtt cttttgcaaa
      181 gttttccaaa aaatctattt tagtgtaaaa ttgagaaaaa aacagagagg acagagtaat
      241 gaatcatttt aaaggcaaac aattcaaaaa agacgtcatt attgtcgctg ttggttacta
      301 cctgcgttac aatctaagct atcgtgaagt tcaggaattg ttatatgatc gtggaataaa
      361 tgtttgtcat actacgattt atcgttgggt gcaagagtac agcaaagtcc tctattatct
      421 ttggaagaag aaaaatagac aatccttcta ttcatggaaa atggacgaaa cctatatcaa
      481 aattaaggga cgttggcatt atctttatcg tgcaattgat gcggacggct taaccttaga
      541 tatctggtta cgaaagaaac gggatacgca agcagcctat gctttcttaa aacgactcca
      601 taaacagttt ggtgagccga aagcaattgt gaccgataaa gcaccttctc ttggctccgc
      661 ctttagaaag ttacagagtg tgggtttata tactaagaca gagcaccgaa ctgtgaagta
      721 tatgaacaat ttaatagaac aagaccatcg acctattaaa cgacgaaata aattttatca
      781 aagtctccgt acagcctctt ccacgattaa gggcatggag accattcgag gaatatataa
      841 aaagaactga agaaatggaa cgctcttcgg cttttcggtg tctactgaaa tcaaggtatt
      901 aatgggaata acagcctaag atatttggag ttcagagagg gcgcgtttga ttttcaaact
      961 tcgcaacaga acccattagc aatatataaa agaaggtatc aagagtcaca gtgaatttat
     1021 tccgaaaagt gaaaagagca aatataaaat ttaataaaaa taagaactaa ataggaaaac
     1081 gtagacgtaa ttttctacgt tttccttttc atatatatta aatattacgg aaaattatat
     1141 aaactaattt agtgttttgt ttgtaattcc taattttgct ccacttttag ataattttta
     1201 ggtctattta actcattaga cattctatgc tcatttttct ccaaatttgt ttcaactctt
     1261 tcgtacttaa ttttgcgtat ttgaaaattc ttcttttaga gtacttttat tacgatacta
     1321 gtatgatata tatctacagc aaacagttaa aatcttccta aaataagcga atagcattcc
     1381 taaaacctat aaaattttta gatgaagcga caagtggaca attaataaac tacttgaaca
     1441 tgaaattatg gatcaccttt caaatttaga aaatggaatt cttatactta ttgcgcaaca
     1501 tttattgatt gcaaaattat gtgacaaaaa gaactagtag aagaaggaat aatggcttga
     1561 taataaagta ctacctatta aaggtagtac tttatttaat ttagtataaa ttaacatact
     1621 actatatttt aggtttcata ttatataaat taataatata ctaccatttg ttggtagtat
     1681 aatttaaagg taataagtta ttcttttatt actatgtttg ggttttatag caaagaaagt
     1741 ttaataagag tttggaccta gcaaacaata ttaatgaggt cattaaatct tattatcttt
     1801 agtgatataa tgaaatatct acacgacaaa attatgatct tgcgtaaagt tataaaatat
     1861 taataaaaat atttta
//
LOCUS       DAXLPY010000165         1837 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.173, whole genome shotgun sequence.
ACCESSION   DAXLPY010000165 DAXLPY010000000
VERSION     DAXLPY010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.173"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..1836
                     /locus_tag="ACF3UF_002784"
     CDS             <1..1836
                     /locus_tag="ACF3UF_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672820.1"
                     /translation="FNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSPADS
                     NQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLLIKG
                     NHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNYAGL
                     PPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLILL
                     SCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKKWYG
                     IFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNRFYV
                     ACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNTDKD
                     RRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKNYVE
                     KILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDDLAQ
                     LLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGITEEL
                     DDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT          602 a          339 c          306 g          590 t
ORIGIN      
        1 tttaataaca tatataataa aaaagaatct ttttatttac gtataaagtg gagcataatc
       61 attatattat cattgttatt tttaacagga attgcttatt tcttttattt tattttttct
      121 cctgcggaca gcaatcaaat gaaagaaata aaagattcgt gggttttcta tacaaaagat
      181 gatcctgatt ttaagtttga cagcaagtac actcgtacga ttcctaccgt ggataaagac
      241 gaaacattca ttatggaaac gacacttgaa aaaccgttgg acgaagcaaa tttactaatc
      301 aaaggaaacc atcaatggat tactgtatat ctaggcgaaa agattttata ccaacggaaa
      361 gattatcagg aagaaagcaa tcccggactc tcattggctg tgatagattt accagcaaat
      421 tatatcggaa aaaaattgac ccttacagtc tcatctcctt atcagaacta tgctggactg
      481 ccaccgaaag tttatctagg aacaactgga ccattgatta gttttattta ttcacaatca
      541 gtgccgcaag tattgacgat gataatcgct gtttttatcg ctatagggac ctttttctat
      601 acgatctact tgatgtataa acaaaaacgt cttgaatact cacttattct cttaagttgc
      661 tttgctttgg cattaggatt tgaagctgta tcagaagata ttttaagtgg tattcttttt
      721 gaaccattcg ttcattcttt tttatctcat ttatttatta tcttaacgtc agctttcatc
      781 atctgctact attggagccg aatgttttac tataaaaaat ggtacggaat tttttgtacg
      841 ttccaacttt tgatttttat cggcgttctg ctttatgcaa cttttactcc tgcagaactt
      901 cctgaattaa tgccgattgc taatattgct agtgttataa gcactttagt cacttcactt
      961 gcatgcattg gcgaagcata taagaataac cgtttttatg tagcttgtac accttggatc
     1021 gtcttggtag ccattatcca ttgcttgatt tacatccaaa cggcattagg tatctatcaa
     1081 acaacgatca attggtctac gattttatat attatcattc taatcgttat tatcagctac
     1141 aatctaatcg atcacatctt aaataccgac aaagatcgga gacaagtaga tttcttaaaa
     1201 atcaaaaatg atttgttgga gcaacattat gagcagcttc gacagcatat ccaagaagta
     1261 aatacacttc gcctggaatt tgtccaagag atggagaatc tgcaagattt aatgcatacg
     1321 gaccaaacaa aagctaaaaa ctatgtggaa aagatattag aagaagcaaa aaatttcgaa
     1381 atgctgtgtt ctttttgcaa ccaccaggtg acaaatctta tcttagcgcg ttaccagaag
     1441 ttagctgcca aacggaatat tcagataacc ttccaagcag atcttcccga agaacttcct
     1501 atcaacgatg acgatctggc tcaacttttg atccacgctt tagagcattc ctttagagaa
     1561 actcatgcca tcgaaaatcc actgtatcga aaaatttatt tgtcgataca cgaacaagag
     1621 gaacatttcg tcatttgttg cgaacatagt gcacattacg atacaaacct atttagtcga
     1681 ggcatcacag aagaattaga tgatcaggaa cgttttgact taatgatgat gaaagacgta
     1741 gcggatcgtt acacaggaac actaacgcag gaaaaagata ctttcattga tcggatcact
     1801 gttcaactct ctcgaaatta cccgaatcct gtataaa
//
LOCUS       DAXLPY010000166         1782 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.174, whole genome shotgun sequence.
ACCESSION   DAXLPY010000166 DAXLPY010000000
VERSION     DAXLPY010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.174"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(1..270)
                     /gene="rpsN"
                     /locus_tag="ACF3UF_002785"
     CDS             complement(1..270)
                     /gene="rpsN"
                     /locus_tag="ACF3UF_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFD3672821.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAVGDHTDLAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(1148..1379)
                     /locus_tag="ACF3UF_002786"
                     /pseudo
     CDS             complement(1148..1379)
                     /locus_tag="ACF3UF_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
     gene            complement(1397..>1782)
                     /locus_tag="ACF3UF_002787"
     CDS             complement(1397..>1782)
                     /locus_tag="ACF3UF_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3672822.1"
                     /translation="LDKEAKSKFASIPNDKKMIVTSEGCFKYFSKAYNVPSAYIWEIN
                     TEEEGTPDQIKHLVERLRTTKVPSLFVESSVDDRPMKTVSKDTNIPIYSTIFTDSIAE
                     KGQDGDSYYAMMKWNLDKIAEGLSK"
BASE COUNT          568 a          306 c          228 g          680 t
ORIGIN      
        1 ttaccaactt gcttttttta ctccaggaat caaaccttga tgggcaagct ctctaaactt
       61 aatacgggac ataccaaact tccgcatata ccctcttgga cggccatccg tctgatcacg
      121 aagcctcaga cgatttggat ttgaatctct tggcaattta gcaaggtcgg tgtgatctcc
      181 tacggctttt aattcttgac gtttgtctgc atatttttca atcattgcca tttgtttctt
      241 tgctttagca attttagact tttttgccat atacatttat actccttctg ttttgattta
      301 gacgtcacaa atcgtaaacg ttacgttttg acattgacac tttaccaaca aaaatttctc
      361 ttgtcaacaa taaataacat gaaataaaaa tcatatgaat agatatccat ttgaaaatga
      421 ttttatcgat acatagagat aatcagatta attaaaagaa cttgtagttt aagtgcaaaa
      481 aataatggtt catttttatt agtccattaa aacataaata ccgttttaag tagcttttct
      541 ctacttaaaa cggcattatg aaagaaacta tagttttatt caatctttta tgtttaactc
      601 gtttattaat gattttgtaa gattgtgacc aattcttata ttataagaaa taaacattaa
      661 gtaactaatt tgaaaaagaa ttgtagctgt attccaaaaa tttataggct aattataagc
      721 ctatcctatc atctcgatag aacttatctt ttttagatag attgttcaga caaacaaagc
      781 tatcttaatt tgatgaagta catccttttg aaaataactt agttcatttt ctattatctt
      841 tcagtaagtg gcacgtagta cctagtctat atgagaaaat tcgccttata tgatattttt
      901 aattctataa atttttaaac attaatgtct attattaaac tcattgctta aacctaaact
      961 aatgagcagc aacagaatag ctgattaaaa aagtaatcct ataagaagta atatactcat
     1021 ctaaatcatt cgccttttct aaaataatcc aagaaagatt taaaaaaatt atatccagct
     1081 attaggataa gtcctatcat aattactcca atagtcattt tcttatcctt tctaaataaa
     1141 aagtctttta tataaagctc tttttgtaat tgtcaataaa gtctttccct ctatttgtca
     1201 attgacaccc tatgtttaaa taaccttcat atctaagttt agccaacatc tcacttacag
     1261 atgctggagt aatgcttaga atttttgcta aatctttatt ttttaacttt ttttcttttc
     1321 gtcaattcct gaattgctaa taaataaatc agtatagtag ttggtttaat ttttaccata
     1381 ctctttttcc tccaatttat tttgaaagac cttcagcaat tttatccagg ttccatttca
     1441 tcatcgcgta gtaactatca ccatcttgtc ctttctctgc aattgaatca gtaaaaatcg
     1501 ttgaatagat aggaatattg gtatctttcg atactgtttt catcggtcta tcgtccacac
     1561 tgctttctac aaataaggaa ggaacttttg ttgtgcgtag tctttcaact aagtgtttaa
     1621 tttgatctgg cgttccttct tcttcagtgt tgatttccca aatgtaagca gaaggcacat
     1681 tatacgcttt cgagaaatac ttaaagcatc cttcacttgt aacaatcatt tttttatcat
     1741 tcggaattga agcaaattta gattttgctt ctttgtctag tg
//
LOCUS       DAXLPY010000167         1764 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.175, whole genome shotgun sequence.
ACCESSION   DAXLPY010000167 DAXLPY010000000
VERSION     DAXLPY010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1764
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.175"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(430..1002)
                     /locus_tag="ACF3UF_002788"
     CDS             complement(430..1002)
                     /locus_tag="ACF3UF_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672823.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGIKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1018..1623)
                     /gene="fic"
                     /locus_tag="ACF3UF_002789"
     CDS             complement(1018..1623)
                     /gene="fic"
                     /locus_tag="ACF3UF_002789"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFD3672824.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          517 a          361 c          259 g          627 t
ORIGIN      
        1 taatatcaca ataggaatgc tgtttattat attagcagca gtgctgattt ttatgatagt
       61 tatttggttc ttaaatgaaa gatctaaaga caatcaacac cgtagggata tggagataaa
      121 atcaatagag tcaatagatt atttatcgat aataacacta aaaaagccac gttcctaaac
      181 gtgacttacg ctgaacgata tgtgttgttt ggtagacgaa caaatcgttc attataaata
      241 tatgatggta tcctaatata gtaagcgtgg ctagcatacc tttaattact ttacctttta
      301 cagttaccat acacattttt tgagcagaaa tcaagtaaat aaaaaaatat tatatttcac
      361 aacatgctaa tagactcata tctagaacgc attaagtatt tacctgtctg gttcgctgag
      421 acttcttttt taactttctt caattttctt ctttattcta aaaagcgtac tgcgactgaa
      481 accggttata gcttcaactt ccttatacga tttacctgaa gtaagcagtt catatgcgtg
      541 cctcttcttc ggtgtgattg ttgctttcgg acgtccttct ctgaaattag gattattctt
      601 tcttgcaaac atttttcctt cttgggtacg ttccacaatc atatcacgtt ccatttctgc
      661 tacactcaac aacgtccgtg tcaccattcg ccccatggac gtattttcaa tcgttcctag
      721 attcaaaacc ttgatcgtta cgttatcatc gagtaaaggt tcaatgatct ctaatgcttc
      781 tctcgtgtta cgagcaaatc gatcaagctt cgtaacaact atttcatctc caggcttcag
      841 accagccaac agctgattga attttggccg atcccgtttt atacccgtaa atttttctga
      901 aaaaatattc ttcttctcta cgccgttctc aagcaactgt tgaatttgtt cttttgtact
      961 ttgagaagcg gttgagacac gtgcatatcc atatttcgtc atttggtcca cctactttta
     1021 caaatcatct atcgtatact cagaataccc ttcatagaaa tagctgacat cgattccttt
     1081 catatataac tcgcgatcgt caattttatc agtcagagca ttggaaatta gatagcgtat
     1141 ttccaaatcg tttatgggac ttcgctccat tgcagaaaga tagtctgctt tatcgattaa
     1201 gttccaatct acaacttttt gcaattcttc ctttaaaatg agatccagcc aaattctagt
     1261 acttcggcca tttccttctc gaaatgggtg agcgatattc atctccacat atttcttgat
     1321 aatctcttca aaagaagttt gtggcatctg atcaatatgc tgtaacgaat gttctaaata
     1381 cataactggt gcaaatcgaa aatttccttt tgcaatattg accgatcgga tttttccggc
     1441 aaaatcgtaa atatccgaaa atagaaattc atgaatttca gataaacctt taaatgtacc
     1501 aacttcgatt tcatttattt ttccacaatc gtacaattct ttcgcttttt gtttactgag
     1561 tttttcttca accttagcca actcaacttg attggttaat cccaatttat tctctaaaat
     1621 catgcgaaat ctccttaact ttatgacata agtttatgaa acactctcaa ccccattata
     1681 tcgcgatttt gtttatgtgt caaaaactat taagtttctg acccccgata gatttttcaa
     1741 gtgtctctat tttgcacagt ctag
//
LOCUS       DAXLPY010000168         1645 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.177, whole genome shotgun sequence.
ACCESSION   DAXLPY010000168 DAXLPY010000000
VERSION     DAXLPY010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.177"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..240)
                     /locus_tag="ACF3UF_002790"
     CDS             complement(<1..240)
                     /locus_tag="ACF3UF_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFD3672825.1"
                     /translation="MSKNNNKNNSSELENCLFNPKKLEDSINKVKRINDLPLVLTNKD
                     LKEQFQISDSTLNRLIKLDNFPRCWFGIKGHYLRDD"
     gene            complement(592..837)
                     /locus_tag="ACF3UF_002791"
     CDS             complement(592..837)
                     /locus_tag="ACF3UF_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672826.1"
                     /translation="MVDKPKKWQYPLVPLSIILSALEEDPISIKMILKHYDNYIAKLC
                     LTNGFNEVGQFITYVDEYMLRQLEVKLIEAILKFKVN"
     gene            complement(831..1232)
                     /locus_tag="ACF3UF_002792"
     CDS             complement(831..1232)
                     /locus_tag="ACF3UF_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFD3672827.1"
                     /translation="MQQNYNEKSIQHQFDAYCKKVLRNEAKSIRKRNTRIKDNEEPLN
                     DVNEGKYPQTNFDEQDVYFLFGMEILISDQKLSAAIDQLSDIRRKIILLYYFADFNDA
                     EIGRILNMSTSGIWYQRTKAVEQLKMGYDLW"
     gene            complement(1469..>1645)
                     /locus_tag="ACF3UF_002793"
     CDS             complement(1469..>1645)
                     /locus_tag="ACF3UF_002793"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3672828.1"
                     /translation="TTQVGKQAKKAKMLPKTGEEDTNMITIFGGLLLLGSLGLIDYKK
                     RESKKSSSRIERSK"
BASE COUNT          508 a          290 c          215 g          632 t
ORIGIN      
        1 atcatctcta aggtaatgcc ctttgatgcc aaaccagcat cttggaaaat tatctagttt
       61 tataagacga tttaaagtac tatcacttat ttgaaattgt tcttttagat ctttatttgt
      121 taaaactaac ggtaggtcat ttattctctt tactttattg atagaatcct ctagcttttt
      181 gggattaaat aaacaatttt ctaactctga tgaattattt ttattgttat tctttgacat
      241 gattatctct tcccttctat tattaaggat taatctatca gctgcctttg tcaaaagcac
      301 ataggaattt cacctctccc caagtttacg gcgagcctta cggaagtatc attatcccaa
      361 cctcaaatca tcgcttttta ttgactataa aaattatttt agaatattta tcgctccttc
      421 tttataataa gagatcatgg cgtaactaaa atatgctcct tgaagtgtta acgtactgat
      481 agaatatatt tatttttcaa tgaacaatag gttttctccc taaaagaatc cgctaatcta
      541 aagtattaga agactctttt tggtagaaaa agtagaaagg ggagttttta gctagttaac
      601 tttaaatttc aatatagctt ctattaattt aacttctaat tgccttagca tatattcatc
      661 cacataggta ataaattgcc ccacctcatt aaatccattt gttaaacata acttagctat
      721 ataattatca taatgtttga gtatcatctt gatcgaaatt ggatcttctt ctagagcaga
      781 taggataata gatagtggaa ctaatggata ctgccatttt ttgggtttat ctaccatagg
      841 tcatacccca ttttcaattg ttcaactgcc ttcgttcgtt gataccagat accacttgta
      901 ctcatattga gaattctacc gatttcagca tcattaaaat cggcaaaata ataaagtaga
      961 ataatcttcc ttcttatatc cgataactga tcaattgctg ctgataactt ctgatctgaa
     1021 attaatatct ccattccaaa taagaaatag acatcttgtt catcaaaatt agtttgtgga
     1081 tacttccctt catttacatc attcagtggt tcctcattat cttttattct agtgtttcgt
     1141 tttcgaatag acttagcttc gtttcgtaat acttttttgc agtaggcatc aaattggtgt
     1201 tgtatagatt tctcattata gttttgttgc acgatcaata tgctccttta tcccctttcc
     1261 actaatacaa caatcagaga gtgccttttt ttcgaaaaaa ctaaaaaaaa acaaaaaata
     1321 atcatacttt ttaggtggaa tttcattctc aaaaaaaaaa aaaacgatta gtatcactaa
     1381 tcgtttttga gtattccttg caaaagccaa attactttta tagttaaaat ttgatattga
     1441 taatcatcct tctttcggta gtgggtaatc attttgatct ttctattcta cttgatgatt
     1501 ttttagactc tctcttttta taatcaatta ggcctaaact tcccaacaat agaagaccac
     1561 caaagatagt aatcatattt gtatcctctt cacctgtttt gggtaacatt ttcgcttttt
     1621 tagcttgttt ccctacttgt gtagt
//
LOCUS       DAXLPY010000169         1631 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.178, whole genome shotgun sequence.
ACCESSION   DAXLPY010000169 DAXLPY010000000
VERSION     DAXLPY010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.178"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            121..1587
                     /locus_tag="ACF3UF_002794"
     CDS             121..1587
                     /locus_tag="ACF3UF_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFD3672829.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          458 a          294 c          335 g          544 t
ORIGIN      
        1 ttaaaaatta cttgctttta tagaaaatta gtttatattt cttaaataag ttttttagtt
       61 aaatttttcg gtaaagatgt ataatatttt ctgaaaattt aaagaattgg ggtatagatt
      121 atggaaaaac agcaagacaa gggcttcttc gggcagccga agggattgtc aactttgttc
      181 ttcactgaga tgtgggaacg atttagttat tacggtatgc gtgcattact tatctattat
      241 atgtacgata cagttgccaa cgggggactt ggattaccac gagcaacagc attagctatc
      301 atgtcgatct acggatcttt gatctacatg tctagtatcg tcggcggatg ggtatctgac
      361 cgagtgttag gagcaaaacg cactgtattc ttcggtggag ttttcattat gcttggccac
      421 atcgtcttgg ctttaccatt tggtgtaagt acattgtttg tttcgatggc attgattatt
      481 atcggaaccg cctttttgaa accaaatgtt tctggcatgg tcggacatct ttattcaaag
      541 actgacttgc gaagagatgc aggattttcg attttttaca tgggtgtcaa cttaggggca
      601 ttattagcac cactaatcgt tggtacaatc ggtcaagaat ataactatca tttagggttc
      661 tctttagctg ctattgggat gttctttgga ttattacaat acatcatcca aggacgcaag
      721 acattagacg gagtgggtac aacaccgccg aatcctttga caactgaaga acgtaaagga
      781 ttcatccgta acttgatcat cgcacttgtt gttatcgctg cagtattcgg cggggcacaa
      841 ctaactggtc atctgacaat tgactttttt gtcaatacaa tcagtgtatt ggggattatc
      901 ttaccgttgt attactttat caaaatgctg acttcaaaag atgtaactgc tgaagaaaaa
      961 ccaagagtat gggcttatat cccattattc cttgcagcaa tcattttctg gtcattacaa
     1021 gaacaaggtt catctatctt agctttattt gctagtgaac gtacacaatc tacgctattt
     1081 ggtgtaacga tccaagcaag ctggtatcaa tcattgaatc caattttcat ctttattctg
     1141 acaccagtat tcgtaacgat gtggacgaaa cttggtgaac gtcaaccatc tacagtagtg
     1201 aaattctctc ttggactttt atttgcagga ttatcgtact tgctattgat gttgccgggt
     1261 atgctttatg gtacaagtgg aaaagtaagt ccattgtggt tgttgggaag tttcttcatc
     1321 gtggttattg ctgaattgtg tctttcacca gttggtttgt ctgtgacaac aaaattagca
     1381 ccacgagcat ttgaatcaca aacaatcgct atttggttct tagctgatgc ttcttcacaa
     1441 gcaatcaatg cacaaattgc acgcttctac acaccgggaa cagaatctgc ttacttcggt
     1501 attatcggtg cagtagcaat cgtcggtggt atcttgctat ttactgtgaa agaaccaatc
     1561 aaaaaactaa tgggctctat tcattaatca atgaacataa aaacaggaat tgcttatttg
     1621 cagcagttcc t
//
LOCUS       DAXLPY010000170         1624 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.179, whole genome shotgun sequence.
ACCESSION   DAXLPY010000170 DAXLPY010000000
VERSION     DAXLPY010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.179"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..432)
                     /gene="amaP"
                     /locus_tag="ACF3UF_002795"
     CDS             complement(<1..432)
                     /gene="amaP"
                     /locus_tag="ACF3UF_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFD3672830.1"
                     /translation="MRKSLKLLLTIVLLLFFFPLAHTLITMQSVVSLPFYLLPFTSYP
                     YIGNNMAQFLFWLSAVLLTFLFIILIIVLFYPRINNYIEKKTDTGKIAIQKKAIENFV
                     LIAAKEEPFIVDPTVKVVIKKKKIKIYVRGKIRKAFQTGERQ"
     gene            complement(1378..>1624)
                     /locus_tag="ACF3UF_002796"
     CDS             complement(1378..>1624)
                     /locus_tag="ACF3UF_002796"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3672831.1"
                     /translation="TPDPETPVTPETPDPETPVTPETSNYKTLQIQKSKVNYKSETNK
                     TLPKTGEAKSSGVFVGIIVLLTSIFAGFKLNLKRKKG"
BASE COUNT          560 a          245 c          184 g          635 t
ORIGIN      
        1 ttgtcgctcc cctgtttgaa aagctttacg tatttttccc cgtacataga tttttatttt
       61 tttcttctta attacaactt ttaccgttgg atcaacaata aaaggctctt cttttgctgc
      121 gattaataca aaattctcaa ttgctttttt ttgaattgct atttttccag tatcggtctt
      181 tttttctata taattattta tcctaggata aaataataca ataattaaaa taataaataa
      241 gaatgttagc aaaacggcac taagccaaaa caaaaattga gccatgttat taccaatata
      301 tgggtaactt gtaaatggta gtaaataaaa tggtaaacta accacacttt gcattgtaat
      361 taacgtatgt gctaaaggaa aaaaaaacag cagtaaaaca atagttaata gtagtttcaa
      421 gctttttcgc atattccacc tcttagatta cgttgtgaat ataattcttt attttattat
      481 tctatggaac tttacaatta aacaaaacct ataaattaaa cttgacacag attttggcag
      541 tttgatttct agaatattct cctttcattt catttatctc actaacttta gttaaactaa
      601 tacgataagt ttaaccaatt actatatctg aaactatcaa agtgagtaac ttgtataaaa
      661 aaatagactg ttcactttat aaattaaaat agtttacgat ataatattat caagtaaaaa
      721 tcctcaagtc aaataaaaat gaatgttcaa tttatttttt atacaagttt tttaattcta
      781 gaaataagtt ccctgcttat aagaagatgt actaaataat gattcttatc tcacaaacat
      841 attatttctt acctccaatc cttttagaaa ccataaaaac tattaactaa caatatttga
      901 aaattcacac tagtattatt taatccacta gacaaaaaat tactatcatc gatataaaaa
      961 atttttttcg attgtatata atattttttt tgagagatga gatttttcta ttgaaaattt
     1021 cttatcttcc aatgtttttt ttgttaaaga agacttaatt tttcgttttt tatttcctgt
     1081 ttctttaatt acaagtcttt gtccctagaa aaaataaaaa atcaaccaat aagtatttct
     1141 gaataatgaa taatataata cgttttttcg gccaagcata ttaaacattg ggcgtgagat
     1201 tcagtatctt gaatatactt atgatttaaa tagactcttt tcttatacat ttcttgccta
     1261 aagattatat atatttctct tctaaagtta tcataatccc tccttaatac ttgagtgata
     1321 taaaacataa ttacaacctg agatagaaca ctaagtattc tatctcagat ctattttcta
     1381 tccttttttt cttttcaaat ttaatttaaa tccagcaaaa atagaagtca ataaaactat
     1441 tatacctaca aatactccag atgattttgc ctctccagtt tttggaagag ttttatttgt
     1501 ttcagattta taattcacct tactcttttg tatttgtaga gttttataat tactagtctc
     1561 tggcgttacc ggggtttctg gatctggagt ctcaggtgtt accggagttt ctggatctgg
     1621 agtc
//
LOCUS       DAXLPY010000171         1620 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.180, whole genome shotgun sequence.
ACCESSION   DAXLPY010000171 DAXLPY010000000
VERSION     DAXLPY010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.180"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(183..1502)
                     /locus_tag="ACF3UF_002797"
     CDS             complement(183..1502)
                     /locus_tag="ACF3UF_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFD3672832.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT          481 a          299 c          323 g          517 t
ORIGIN      
        1 attctttggc acattttatt gaaatatgta tcactaatat ccctatcaac tgattttgac
       61 taaaaagtta cttcaaacat tcactgttca aaaatattga ggaataaatt ttgggtgtaa
      121 ggcattttga gcatacttct ccctggataa cttcccagta aaaaaatcgt tagattgttg
      181 gattagatcc attgactggc tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga
      241 tacacatgat aactagataa tttgagatag actcgtctac ccgtttggac taatttccca
      301 gcaactttca gaaacttcaa tcgaatagaa tgaatggtca ttcccttttg gacttcttca
      361 aagccaatcg ttcttaagaa gttgactaag ttgtaagcta tcaagctgag catcattcgg
      421 acatgattct ccaaaaagcg aggactgtct gttttgtcaa agtaaaagcc agctttcgct
      481 tctttaatga agttctccat tgtgccacgt ttggcataga tagaaaagat ggtatcagga
      541 gaaacatttt ctgatagatt cgtcacgata aattcatgtc gaaagagtag ttcgcccgct
      601 tcacgtgttg agcgtataca cacgcgacga ctttgtgacc aggattgtgc ttgataagtg
      661 gtcgagaagt actgaacttc tcgttcttcc cacttttgat tatcgccata aagtactgat
      721 ttctcagcta tttgacctag tctacgatta ttcttcagtc gaataacata atgactcttt
      781 tttgattcac acgaatcata cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag
      841 atgtcagtgt ttggtagaga gtgattatag tgctctaata aaggtgtgag aaactccttt
      901 acgccttttg atgtatattg atttcctgaa cgtagttcag cttttaagaa gtcaccagtc
      961 aatccgtcaa aagctaccaa tggatggtaa ccataggttt ggtagtgtgt attataattc
     1021 gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc
     1081 gtatcattac ggatgaggcg tgctttatcg ataagttctt ggttcaaagc ttgaagttca
     1141 tggatattct cctcagatag tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt
     1201 tctttcctat ctaaaacagc tttaaacaca ggatcttgtc tcaggagatt agctgcagaa
     1261 tcagctgagt aaccagcaat taattgcata atgaactgct caagtatgga taagttgtca
     1321 tgagtaaaat acgctcgttc gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa
     1381 ccaaagatgt tcatcagctc tttcactagg acgagacccg aatcactcga taattgacca
     1441 cctgtatgag aaatagtgat atttgaattg aattttactt ggtttttgtg taagctagtc
     1501 atgaaaagaa ctcctttctt ttggttggtt tagtcacttt aaccatagca gaaaggggtt
     1561 cttttttcat cacttaacgg gtgaagatga aaaagtaatt gtaagctgcc gtgaggcagt
//
LOCUS       DAXLPY010000172         1580 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.181, whole genome shotgun sequence.
ACCESSION   DAXLPY010000172 DAXLPY010000000
VERSION     DAXLPY010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1580
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.181"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            192..887
                     /locus_tag="ACF3UF_002798"
     CDS             192..887
                     /locus_tag="ACF3UF_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFD3672833.1"
                     /translation="MRSSKYTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVL
                     KGIEIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFA
                     QLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKS
                     AYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKAKGVTELAI
                     YQKRKRIMVPLPV"
     gene            complement(924..1421)
                     /locus_tag="ACF3UF_002799"
     CDS             complement(924..1421)
                     /locus_tag="ACF3UF_002799"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3672834.1"
                     /translation="MNNQIALAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
     gene            complement(1477..>1580)
                     /locus_tag="ACF3UF_002800"
     CDS             complement(1477..>1580)
                     /locus_tag="ACF3UF_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFD3672835.1"
                     /translation="LESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT          507 a          284 c          254 g          535 t
ORIGIN      
        1 aataattaca cacacacaat tttttaaggt cttaaaacca tcatatatgc aaaagaagct
       61 aacctttatt actaaattag acccgtggtg ctagttaatt ttttcctaga ggaaaatgtc
      121 taaacatgtt ggtaaatcaa caaaaaaacg catatagtag tctcaaaact cccaagaaat
      181 gaggactaca tatgcgttca tcaaaatata ctgaacattt tgacttagcc aatcctgtta
      241 ctaaagtcga tgatatcccc gattatgaaa tgtacagtca aacaatcgat agcttaaata
      301 agcgttttgg caatcgtgtt ttaaaaggca tagaaatcgg ttacatcgct tctgaaaagg
      361 atcggatcat cgactattta gccgataaag attacgattt aaaattactc agtgtgcatc
      421 ataatggtca atttgattat ttagatgacg aagtcaaaga tatggatcct gctattgtga
      481 ttcctcagta ttttgcacaa ctttcagaag cactagttgt tatagaagca gatgtctttg
      541 ctcattttga ctatggtttt cgggtatttg gtctatccgt tgctgaattt aaacaatatg
      601 aagcgcagtt tttaccgatt ctagatcaag taatcaaaaa taaattggca ttcgaattaa
      661 atgctaagag cgcttacttg tatgacaatt tagcgttata tgaatatgtc atcgatttat
      721 atctttcacg tggtggtacc ttgtttagtg ttggatcaga tgggcattac cttgaacatt
      781 tccgtttcca tttcgatgat ctttttgctc tgttaaaagc aaaaggtgtg acggaattag
      841 cgatttatca aaaaagaaag cgaattatgg ttccattacc agtctaaaaa aacgtcctca
      901 gcatcaaaag tgaggacgtt tttttagatt tctttttcta aaatcggaca aatacgatct
      961 tgttttccta aaggaaaatg tttgatcccg atttttttaa atccatgacg ttcataaaaa
     1021 cgaatacctg catgattttt ttcataaaca gtcaaacgta aataacgttt ttgtttcgtt
     1081 ttagcataac gattcgcttc atcgagtaac cgttgcccta accctttgtt ttgataatct
     1141 ttgagcagat agagccgttg aatctctata gcatcttttt catcattgac tttcatataa
     1201 ccaatgagta tttgatgatc cttaatacca ataaatttac tggttgactg tgccaattct
     1261 actgccaata tttcagttgt caattgtgtc tgtaaatatc cttgcatatc aagtggatct
     1321 gcgccatcga taaacgattc ataaaaactg acaacactta caacttgtaa agcatctaga
     1381 tcatcataat ctaaatacgc tagtgcgatt tgattgttca tctaactcct ccttttgaca
     1441 tagtatacta taaatcaccc gtggtgctag ttaattttaa tatcctaaag aatatctcaa
     1501 agttccttca aaacgtcgtt gtgctcgact taatagaaca ctgtaagcca gtaatatgct
     1561 ttcaaatcta ctctctagcc
//
LOCUS       DAXLPY010000173         1580 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.182, whole genome shotgun sequence.
ACCESSION   DAXLPY010000173 DAXLPY010000000
VERSION     DAXLPY010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1580
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.182"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            5..403
                     /locus_tag="ACF3UF_002801"
     CDS             5..403
                     /locus_tag="ACF3UF_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFD3672836.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="ACF3UF_002802"
     CDS             387..1082
                     /locus_tag="ACF3UF_002802"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFD3672837.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
BASE COUNT          597 a          228 c          313 g          442 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta ctaactatta cttatttctc
     1201 atttaaacga tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt
     1261 tttgaataaa tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc
     1321 tctagtataa cagaataaga agaacaagtc cagaagggat atttttagtc ttttttaaaa
     1381 taacttttca gtcgagtttg agtttatgat agttgttttt gaagcgatac ggcaagtgaa
     1441 aaaataggga agcatgaaag aatctactta atggcgcatt gattcatgtg atagaaataa
     1501 aaaacttttt taaattatat cctcatgatt gtaacaaatc cagtgatttg ttttggtaca
     1561 aataaaaaaa ggccccgatg
//
LOCUS       DAXLPY010000174         1580 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.183, whole genome shotgun sequence.
ACCESSION   DAXLPY010000174 DAXLPY010000000
VERSION     DAXLPY010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1580
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.183"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            88..870
                     /locus_tag="ACF3UF_002803"
     CDS             88..870
                     /locus_tag="ACF3UF_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672838.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKAKLKKIADIANCSVEDLLFDEGFIS
                     EKSQVKLINELKEENSKLKEKIKYYECLFDGIESLLNSRKNS"
     gene            910..1521
                     /locus_tag="ACF3UF_002804"
     CDS             910..1521
                     /locus_tag="ACF3UF_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3672839.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
BASE COUNT          636 a          205 c          294 g          445 t
ORIGIN      
        1 tattggattc tataataaaa aatatattta caaaatatta ctcaaaagaa tttgaagtaa
       61 cccaaattcc ataagagagg tgattgtatg aagccaaatc cttcagaagc aggaaaacga
      121 atcaaacaat tacgcctttc atgtggtttt actatggaag aacttggaag gaaaatagat
      181 aattcaccac gtgcgaccat atccaactgg gaacgtggga ccaatttacc aaatccacaa
      241 aagctgaaat tattatcaac tatcactaat tcaacaattg actggattaa atggggaact
      301 ttagaagaat atataacttc ataccttatc gatatagggt atgagctata tattaaggac
      361 tttccagaaa tacctcacaa agtctttaaa gacattcaag aaagatatag taatacgttt
      421 tcgctaaata aagactatga gttattgaat cctataataa aaaatatatt tacaaaatat
      481 tactcaaaag attttgaaga ttatcgagac atagaagtta aaccagaccc taaaaaggta
      541 gggagaaaaa ttcgttctat tagaaaaaaa ttaggactta ctatgcagga atttgggtac
      601 gaggtttcta attctcctag aagcactgtg tcaacatggg aacatggtgg taacttaccg
      661 aacaaagcca aactaaaaaa aattgcagac attgcgaatt gtagtgtaga agatttgctt
      721 tttgatgaag gctttatttc tgaaaaatcc caagttaaat tgataaatga actcaaagaa
      781 gaaaattcaa agctaaaaga aaaaataaaa tactatgaat gtttatttga tggtatagag
      841 agtctgctga actcacgaaa aaattcctag ttaattaaac tagagtaaaa ttatttgtag
      901 gtgttaaata tgttagttgg ctatgcacga gtcagttcag atgatcaaaa tttggaaaga
      961 cagcttgaag aatttagaaa aattggtgtc gaaaaagtat ttgctgagaa aaaatctgga
     1021 cgtaacacag tagaacggcc agagttcaat aaaatgttgt catttgtcag agaaggggat
     1081 acgcttgttt ttgagtcgct tgaacgctta ggaagaaatt ctgatgaaat actagaaaca
     1141 gtatctttta tagataaaaa tggtatgggc ttaatggttt tgaatttacc aattttagat
     1201 acaaaatttg gtgatccaaa cttagaaaaa cttgttagaa gcttagtaat taacattttt
     1261 tcttggacgg ctcaaaatga gagggaggaa attaagagaa aacaaaaaca aggaatagca
     1321 attgcgaaga agaaaggagt ctataaagga aaaccctacg aatattcttc tactgcaaag
     1381 aatccacaaa agaggtttat ctataatgaa atagtaagaa tgcttggaga aggtgttccg
     1441 attaagcgaa ttgcagaaaa aacaggaaca aatagaaatt tagtctatag aataaagaaa
     1501 agaataagtg aatctgattg attttaagtt ctttgagaaa tcaatgttac gagagaagga
     1561 ttctaagcct gtttcaaact
//
LOCUS       DAXLPY010000175         1523 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.185, whole genome shotgun sequence.
ACCESSION   DAXLPY010000175 DAXLPY010000000
VERSION     DAXLPY010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.185"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..1217)
                     /locus_tag="ACF3UF_002805"
     CDS             complement(<1..1217)
                     /locus_tag="ACF3UF_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672840.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQYNGNILLKNEDNKRFFIKKEKDFPIYNIYLHFYKASYNYHLIDFMYK
                     YPRSVLKDFAKEQFTSVSTVFRYAKLLIPYFRRYHITFHPFQLELNASEANIRSFFYY
                     FYWNSTRESSDKWPFHIEQKEIEKYIVAFEGIYDITLTIFQKRVFSFWLAINIERSSF
                     RKVRVDNEYKSVISDDPHFNLLKKWSKQINLSFNSDELCFLYRIIYSFGVIDGNAIYE
                     NSHAYAHQRQNTCSYRAVENLEKVLQSMFRFSLDIKDPELIFNFIAFHERSYLFYGNP
                     DLFFNRSYIEEMKEEEPRTYHIMEKLKKELQANADLDVSKKLENWAQLFLDYYYVLDY
                     YDLFLTNVKPIKI"
BASE COUNT          554 a          230 c          173 g          566 t
ORIGIN      
        1 aaaatcttaa tcggtttaac atttgttaaa aataaatcat aataatctaa cacataataa
       61 taatccaaaa ataattgtgc ccagttttct aatttctttg atacatccaa atccgcattt
      121 gcttgtaatt cttttttgag tttttccatt atgtgataag ttcgaggttc ttcttctttc
      181 atttcttcga tatacgaacg attaaaaaaa agatctggat taccataaaa tagataactt
      241 ctttcatgaa atgcaataaa attgaatatg agttctggat cctttatatc taaagaaaaa
      301 cggaacatgc tttgtaaaac tttctccaaa ttctcaactg ctcgataaga acaagtattt
      361 tgtcgctgat gtgcatatgc atgactattt tcatatattg catttccatc aattactcca
      421 aaagaataaa ttattcgata aaggaaacac agttcatcgc tgttaaaaga aagattgatt
      481 tgttttgacc acttcttcaa aagattaaaa tgcggatcat ctgagataac tgatttatat
      541 tcattatcta ctcgtacttt tctaaatgaa cttctttcta tattaatggc taaccaaaaa
      601 gaaaatacac gtttttgaaa aatagttaac gtaatatcat aaatcccctc aaaagcaact
      661 atatacttct ctatttcctt ttgttcgata tgaaatggcc acttatcact actttcacgt
      721 gtagaattcc aatagaaata ataaaaaaag ctacgaatgt ttgcctctga tgcattcaat
      781 tctaactgaa atggatgaaa tgttatatga taacgcctaa aatatggaat taagagcttc
      841 gcatatctga aaacagtaga tacactagta aattgctctt tagcaaaatc ttttagaaca
      901 cttctaggat atttatacat aaaatcaatc aaatgataat tataagaagc tttataaaaa
      961 tgaagataaa tattataaat aggaaaatct ttctcttttt ttatgaaaaa tcgtttatta
     1021 tcttcatttt tcagaaggat attaccatta tattgcttaa ataaatcctc tagttcttct
     1081 atatagtgta agactgactt ctccgtaaca ttaagtaaat ttctaagttc ttccattgca
     1141 caccaattgt ctttttctaa caaataatct aataaaacta cttttttgaa agatgtttta
     1201 gttaaaaaag tttgcatcat ttcacctcaa taagttactt ttgtttattt taatcaaaga
     1261 ataaacttct ctcgttcgac tataactgat cgaacaaaag aagcctttta ataaatataa
     1321 tctcacttac atacataggc tagttatttg cttctagctt atgataagta tataaacgga
     1381 tatcgatttc ataattgttt tatcttaaac atcatagctg taattgtttt tatttttaca
     1441 tgaagaatta ttataatcta gtttaatttt tttctgaaat atagaataaa aataaaaaca
     1501 tcttttcatt ttgagttatt aat
//
LOCUS       DAXLPY010000176         1456 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.186, whole genome shotgun sequence.
ACCESSION   DAXLPY010000176 DAXLPY010000000
VERSION     DAXLPY010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.186"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            244..>1456
                     /locus_tag="ACF3UF_002806"
     CDS             244..>1456
                     /locus_tag="ACF3UF_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFD3672841.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     ETILEFNDSYHFDQIVIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFS
                     RMFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQH
                     FLENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGK
                     GRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQ
                     VIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQ
                     SQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARK
                     FTRLVDTLLRKH"
BASE COUNT          476 a          289 c          261 g          430 t
ORIGIN      
        1 atttcctcct gtagcgtttg tctaccctgt ttagtctgtt acccgaacca ctgttatcac
       61 taccaactca ttagctgttt cgataatgga ctagactttc aaatagtagt ttggaaggca
      121 gcttctagct cttttatcac cgtattctat taggcgaggt tgtggctata cagtgagttt
      181 ctgggaaatc ccacagtatc gaagcatttt ccaaaattta tatcgaaagg aggtccttct
      241 tccatgaaat tatttgtcgg tattgacgtt agctctgaaa aactagatgt ttgtttttta
      301 acagacgaca atcaattgtc tatcttatct gaaatctctg ttgccaatga catcgaaggt
      361 gcttcattca tacgagaaac aattcttgaa ttcaatgaca gctaccactt tgatcaaatt
      421 gtgattggca tggagtcaac gtccatgtac agcttccatc cttccatgtt ttttcatgaa
      481 gatgagaaac taaagaagct caacacactt gtaacgattg aaaatccttt tcgggtgaaa
      541 caatttagtc gcatgtttga tgagaataaa actgatcgaa acgatgcatt aagaatcgct
      601 gatttcttgc gtattcaacg attcacaact tcccctatca aagaagagaa atacatggcc
      661 ttacagcgtt taacacgtac tcgctatcaa cttattaagc aattgattcg tacaaagcaa
      721 cattttcttg aaaatctaac gtacaaatgt aatacgcttg ctcgagaaat gcgagacgaa
      781 tcgacgagtc tttttagtgc aaccctcatt tcactcatga cggaagattt cacattggat
      841 gaacttgctg agcttccttt agaagctttc tgtgatttac ttcaagaaaa aggaaaaggc
      901 cgtttcaagc aaccagaaaa aatcgctaaa gcaattcaac gtgcaattac catgagttac
      961 cgcctaggtg ctcttgcaca agaatcaatt aatgttgttt taagtgttct cgtacgagaa
     1021 atacgagcac ttgaaaaaaa tatcaaagaa ttagataaag ccatcgaaca agtaattgtt
     1081 gtcattccag aatatcaatg cttaaccagt attccaggcg ttggtaaagt ctatgctgcc
     1141 ggtttaatcg ctgaaattgg tcaaatcgaa agatttgaag atcagacaaa attggcaaaa
     1201 tacgctggat taagttggaa agtgaaccaa tctggaaact atcagtcgca aaatacacct
     1261 ctgacaaaac aaggaaatcg atattttaga tactacttag ttgaagctgc caactctgta
     1321 aaaaattatc ttcctgaata caaagctttt tatcaaagta aatataagga ggttccaaag
     1381 catcaacaca aacgtgcact cgtcctaacc gcaagaaaat ttacgcgtct ggtggatacg
     1441 ctactacgta aacacc
//
LOCUS       DAXLPY010000177         1430 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.187, whole genome shotgun sequence.
ACCESSION   DAXLPY010000177 DAXLPY010000000
VERSION     DAXLPY010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.187"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..1350
                     /locus_tag="ACF3UF_002807"
     CDS             <1..1350
                     /locus_tag="ACF3UF_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFD3672842.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
BASE COUNT          564 a          225 c          309 g          332 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa
//
LOCUS       DAXLPY010000178         1361 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.188, whole genome shotgun sequence.
ACCESSION   DAXLPY010000178 DAXLPY010000000
VERSION     DAXLPY010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.188"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..486
                     /locus_tag="ACF3UF_002808"
     CDS             <1..486
                     /locus_tag="ACF3UF_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3672843.1"
                     /translation="LKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKE
                     QQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFS
                     NNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVI
                     K"
     gene            complement(693..1217)
                     /locus_tag="ACF3UF_002809"
                     /pseudo
     CDS             complement(693..1217)
                     /locus_tag="ACF3UF_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          445 a          254 c          260 g          402 t
ORIGIN      
        1 ttaaaggaag cgatcgatca aatcaagacg gctgtcttgt atcctcataa cggattaccg
       61 attttattga tgggtgtaag cggttcagga aaaacctttt tggcagaaaa aatttatgaa
      121 tacgccaagg aacaacaggt gatagaatca aatgctccat ttatcgccta taattgtgct
      181 caatacttta atttctcgat taacaagatc gtagaaaatt taacgatcct tgatgcaatg
      241 aaggttttga gattggtaca aaaggccgtc aaagaactcg aaaaactaat ggggatcgaa
      301 ttttcaaaca atcaattgtt cttgctttac atgcactgct gctcaatgat cgaacgtatt
      361 ttacgcaaag aaagtgtaga tgaacaagca gatatcaaag aatatattca aaaagaggga
      421 cataattatg aaatatcaaa atacccggct tacaaaacga agtttgaaag tactgtaata
      481 aagtaagatt taaataagca taaacaaggt aagaaccata ggggctgtgt caagtccaaa
      541 atcttgtgta aaaaggaaat ctcaaagtac gatgttttgc cttgttgagc ctagctacgg
      601 tccaatatgc tggtaagaag tgtcaagagc aaaaagcgaa gcgtctcttg atacttctca
      661 ccagtatatt atactattgg cggcttaatg tgctaaatct cgttacgatc aaattcaaga
      721 tattttctag gtgcagaagt ccattcgtca tccttttcca tcaataaagc accgatgata
      781 cgaataacag aatcacaatt tgggaaaatt cggacaacac gttcacgacg gcgtacttct
      841 tcatttagtc tttcaagaac attcgttgtt ctcaatcgtt gacggatatt ttctggtaaa
      901 accattactt gcatggcatc ttcgaagccc tcatccaata ttttacaggc agttgcgact
      961 ttcttgtctt ccccatattt atccataata agttgtttac gttctccagc cagctcgatg
     1021 cttgccgttt tgaagatggc tttaaagtct tctttgatat cgcttgagat tttcttggag
     1081 aatttgtcgg aaatgttgcg aaggagatgt gcttggcatc tctgctagct cgcacaaaga
     1141 aggtattctt tcacagcttt tgtgagccct atatgcgcat ccgagatgac catctttact
     1201 cctgaaagac cgcgttcttt caatccgaga gtgtaaaata ttttgtgtaa atagaaaaaa
     1261 ggaagtccct tcagtagaat agagttacca caacacattc acagaaaaga ggacttccat
     1321 atgaacgatt ttactacaga aattctaaag actctagcga a
//
LOCUS       DAXLPY010000179         1358 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.189, whole genome shotgun sequence.
ACCESSION   DAXLPY010000179 DAXLPY010000000
VERSION     DAXLPY010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.189"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            82..>1358
                     /locus_tag="ACF3UF_002810"
     CDS             82..>1358
                     /locus_tag="ACF3UF_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFD3672844.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLIN"
BASE COUNT          462 a          262 c          257 g          377 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatca
//
LOCUS       DAXLPY010000180         1351 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.190, whole genome shotgun sequence.
ACCESSION   DAXLPY010000180 DAXLPY010000000
VERSION     DAXLPY010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.190"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..290)
                     /locus_tag="ACF3UF_002811"
     CDS             complement(<1..290)
                     /locus_tag="ACF3UF_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3672845.1"
                     /translation="MMRKWKVVVGSLGILIALFILGACSTNSKDKVASNEKLKVVVTN
                     SILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVN"
     gene            complement(287..1129)
                     /locus_tag="ACF3UF_002812"
     CDS             complement(287..1129)
                     /locus_tag="ACF3UF_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFD3672846.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAMGMNVNFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISAAVGASSSLLGLFIGYNFNIAAGSSIVLTAASLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(1131..>1351)
                     /locus_tag="ACF3UF_002813"
     CDS             complement(1131..>1351)
                     /locus_tag="ACF3UF_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3672847.1"
                     /translation="SERIIMDTLKELKNQGKTVLIVHHDLSKVKKYFDNIILLNRNVI
                     AHGSVESVFNEENLKKAYGDTIFIGERE"
BASE COUNT          493 a          259 c          159 g          440 t
ORIGIN      
        1 aagttaacac cattataaaa aatcaagtct gcttttgaag ttttttgaac atcttcaggc
       61 aaaggttcat attcatgggg atctttccca ataggtacaa tactgtgtaa atcaatttta
      121 tcctttgcta tattttcagt aatatctgct aaaatcgaat tagtaactac tacttttaat
      181 ttttcgttcg aagccacttt atctttacta tttgttgaac acgctcctaa tataaaaaga
      241 gcaatcaaaa tccccagact tcccactact actttccatt ttctcatcat aacgatctct
      301 ccttctttct taaaaatttt tgttttggtg agattagaaa actaattaca aataaggatg
      361 ccgctgttaa aacaatactt gatcctgcgg ctatgttaaa attataacca ataaacaatc
      421 caagcaatga tgagcttgcc ccgactgctg cagaaataaa tatcatagtt ttcaagctat
      481 ttgcatataa atatgctgta gctgctggcg tgattaacat tgcaacaatt aatatagtcc
      541 ccacactttg catagctgtt actgctacta aagttaatag aaccatcagt agataatgat
      601 aaaaattgac gttcatcccc attgcttttg ccattaatgg atcaaaagaa gtaattaata
      661 attctttaaa aaatagaact actataacca acactaaaac agaaacgcca atcgtaatcc
      721 acttatcaat atcttgtaca gctaaaatgt ttccaaataa gatatgaaat aaatccgttg
      781 agctatttgc aactcctata aggataactc ctagcgctaa aaaagaactg aaagtaatac
      841 caattgctgt atctcctttt attacactat tgctttttat aaaagtaata atgatagaag
      901 ctaatagacc aaatacaata gcaccaataa aaaaattaat acctaaaata taagaaattg
      961 ctactcctgg caaaacagca tgagaaatag catcgcccat aagagacatt cctcttaaaa
     1021 taataaaaca acctactgtt ccagaaacaa tccctataac tacagatgta attagagcat
     1081 tctgtaaaaa gtgaaagtca tacagaccat taataaaatt ttgaagcatg ttattccctc
     1141 tctccaataa atatagtatc tccataggct ttttttaaat tctcttcatt aaatacagat
     1201 tctacacttc cgtgagcaat tacatttcga ttcaaaagaa taatattatc aaaatacttc
     1261 tttaccttgc ttaaatcatg atgcacaatt agcactgttt ttccctgatt tttcaattct
     1321 tttaacgtat ccataattat tcgttcacta a
//
LOCUS       DAXLPY010000181         1350 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.191, whole genome shotgun sequence.
ACCESSION   DAXLPY010000181 DAXLPY010000000
VERSION     DAXLPY010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.191"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            29..1302
                     /locus_tag="ACF3UF_002814"
                     /pseudo
     CDS             29..1302
                     /locus_tag="ACF3UF_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          443 a          278 c          239 g          390 t
ORIGIN      
        1 ccacaacaca atcaaaggag cgttctgtat gcctgatctt catcttatca aactattact
       61 aggaatcaaa gatggaaaca ttcaaatcac tcatgtcgag aagaaaaaaa tacattcaat
      121 caacagtatc gttgtttctg ccacgctcat taaaacgatt cagccctgtc ctcagtgtaa
      181 acaggtgaat caacatgggc tgatcgttaa gaacggaaag aaaaaatcgc tggtccttct
      241 caataagtgt gcgaatcaac ggacttatct tgctttggca aagcaacggt acctctgtcg
      301 tggctgtcac acctatttta cggcgaatac ctacattgtt gaaaaaaact gttttatcgc
      361 caaacaagta cattataaaa tattggagga attgactgaa aaacaagcaa tgacgacgat
      421 ttctaaacat tgcggcgttt cttggtcaac cgtttcgcga acactcgctt ctctgctccc
      481 catgacaaac gtgaaaataa attggttgcc tcgctgttca ttggtagatg aatttcgttc
      541 attgaaaaat caagtcggtc cctattcttt ttcttgtatg gatggcgata ctgggaaatt
      601 actggatatt cttccttcac gtaagaagaa agatctcatt tcttatttta tgcaatttga
      661 acgacgtgca cgtttaaacg taaaaatact cgtaacagat atgaacgcct cttatgcttt
      721 gctgataaaa gagtgctttc ctcatgccaa actcgttgtg gatcgctttc acatcgtcaa
      781 gcacctcatt cgcagtttta aggatatttg actatgagtc atgaaaagct tcgaccgaaa
      841 cgatccaata caagccaaac actatcgaca agtgaaggct ttatctcgac ttctgatcaa
      901 acgacaggac acgcttgttt atgataaatg gacaaaatgg cgtaattttg gttgggccta
      961 tttaaccgaa agtgaagtcg tagaacgtct actttctact tctgatgaac tacgaatagc
     1021 ttatgcttac tatcaagaaa ttcttcaagc tttttatgac aaagaagcgg acatcttctt
     1081 tcagcttgta aaaacaatgc ccaagtcggt tccaagagaa ctgcatcata taaaaaaagc
     1141 gtttataaac tatgaatccg gcattcgttt agccttagag ttgccttact caaatggcaa
     1201 aatagaaaat ctgcataccc acatcaaagc attgaaacga atagcttacg ggttaggatg
     1261 agaaccagaa ttttcttaat caatcatctg atcacttatt aaacataaaa aaacatctaa
     1321 agcagaaaat caattctacc ttagatgttc
//
LOCUS       DAXLPY010000182         1311 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.192, whole genome shotgun sequence.
ACCESSION   DAXLPY010000182 DAXLPY010000000
VERSION     DAXLPY010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.192"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            200..742
                     /locus_tag="ACF3UF_002815"
     CDS             200..742
                     /locus_tag="ACF3UF_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672848.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1311
                     /locus_tag="ACF3UF_002816"
     CDS             898..>1311
                     /locus_tag="ACF3UF_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFD3672849.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMA"
BASE COUNT          532 a          148 c          255 g          376 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgg aatggcaaca
     1261 ctttttttga caaaaattat aaggtgttgt gaatgctgcg gtgttatggc t
//
LOCUS       DAXLPY010000183         1297 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.193, whole genome shotgun sequence.
ACCESSION   DAXLPY010000183 DAXLPY010000000
VERSION     DAXLPY010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.193"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..152
                     /locus_tag="ACF3UF_002817"
     CDS             <1..152
                     /locus_tag="ACF3UF_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3672850.1"
                     /translation="TYLNTLLSNSFIINQIVEPQPPENMMDIPGMADEMRRPMMLIVS
                     AKKKM"
     gene            185..1093
                     /locus_tag="ACF3UF_002818"
     CDS             185..1093
                     /locus_tag="ACF3UF_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFD3672851.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1090..>1297
                     /locus_tag="ACF3UF_002819"
     CDS             1090..>1297
                     /locus_tag="ACF3UF_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672852.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDN"
BASE COUNT          462 a          185 c          294 g          356 t
ORIGIN      
        1 ccacatatct aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac
       61 agccgccaga gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga
      121 tgctgattgt atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat
      181 gtaaatgaga tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga
      241 acgtattcga attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga
      301 atttcaggat tatgatatta catattttgt aagtgatata gaaccgttta tatctaatga
      361 tgactggctt aatcaatttg ggaatataat aatgatgcaa aagccggagg atatggaatt
      421 attcccacct gaagaaaagg gattttccta tcttatgcta tttgatgatt acaataaaat
      481 tgatcttacc ttattgccct tggaagagtt agataattac ctaaagggcg ataaattaat
      541 aaaggttcta attgataaag attgtagaat taaaagggac atagttccga ctgatataga
      601 ttatcatgta agaaagccaa gcgcaaggga gtatgatgat tgctgcaatg aattttggaa
      661 tgtaacacct tatgttatta aaggattgtg ccgtaaggaa attttatttg ctattgatca
      721 ttttaatcag attgttcgcc atgagctgct gagaatgata tcatggaagg tcggcatcga
      781 aacaggcttt aaattaagtg taggcaagaa ctataagttt attgaaaggt atatatccga
      841 ggatttgtgg gagaaacttt tgtccaccta ccggatggat tcctatgaaa acatatggga
      901 agcattattt ctatgccatc aattgttcag ggcggtatcc ggtgaggtgg cggaaaggct
      961 tcattatgcc tatccggagt atgataggaa tataacaaaa tataccaggg acatgtataa
     1021 aaaatacact ggtaaaaccg gctgcctgga tagcacatat gccgctgata tagaagagag
     1081 gcgggaacag tgattacaga aatgaaagca gggcacctga aagatatcga taaacccagc
     1141 gaaccatttg aggtgatagg taagattata ccgaggtatg aaaacgagaa ttggaccttt
     1201 acagaattac tctatgaagc gccatattta aaaagctacc aagacgaaga ggatgaagag
     1261 gatgaggagg cagattgcct tgaatatatt gacaata
//
LOCUS       DAXLPY010000184         1282 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.194, whole genome shotgun sequence.
ACCESSION   DAXLPY010000184 DAXLPY010000000
VERSION     DAXLPY010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.194"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            81..1253
                     /locus_tag="ACF3UF_002820"
     CDS             81..1253
                     /locus_tag="ACF3UF_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HFD3672853.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          478 a          235 c          227 g          342 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
      841 gccaagttca cttcctaaga aatatcttta ccaccattcc taaaaaaaat tcaaaatctt
      901 tcagagaagc tgttaaagga atttttaagt tcacagatat taacttagcg cgtgaggcta
      961 aaaatcgatt gattcatgat tatatcgatc aaccaaaata ttcaaaagct tgcgcatcat
     1021 tggatgatgg attcgaagac gcctttcaat ataccgtaca aggaaattcc cacaatcgac
     1081 taaagagtac caatctaatt gaacgactga atcaagaagt acgcagaaga gaaaagatta
     1141 ttcgcatctt ccccaatcaa acatcagcca atcgcttaat tggagccgtt cttatggacc
     1201 tacatgatga atggatttat tcttcaagaa aatacatcaa ttttgataag tagaaatggt
     1261 aaaaacattg tatagcattt ta
//
LOCUS       DAXLPY010000185         1271 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.195, whole genome shotgun sequence.
ACCESSION   DAXLPY010000185 DAXLPY010000000
VERSION     DAXLPY010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.195"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..582
                     /gene="mobL"
                     /locus_tag="ACF3UF_002821"
     CDS             <1..582
                     /gene="mobL"
                     /locus_tag="ACF3UF_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HFD3672854.1"
                     /translation="MNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVL
                     TKEPEYQEYIQISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQD
                     SQIKPLIESMDQMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLR
                     QLNRTINAHEEKYHASKAYEEQQRRIQMEQERQ"
     gene            603..938
                     /locus_tag="ACF3UF_002822"
     CDS             603..938
                     /locus_tag="ACF3UF_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672855.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            1084..>1271
                     /locus_tag="ACF3UF_002823"
     CDS             1084..>1271
                     /locus_tag="ACF3UF_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672856.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT          502 a          192 c          264 g          313 t
ORIGIN      
        1 atgaacttat taaatgaagt atataaaacc ctacctgaca aacgttcgga atggcattat
       61 ggggatgaaa aacgaaccaa actttcacca tacacaagag agaaactcga tgagttaacc
      121 aaatatgtgt taacaaaaga acctgaatat caagaatata tacagatttc aaaatcattg
      181 aaagaagaag caaaaagtct ttatggggaa agcaagagag aatcaaagga tgcagaaaaa
      241 aatgctctct ttgatttgaa gaagcgcaca ggaaatgcca ttctaacaga actgaagaaa
      301 caggatagtc aaataaaacc tttaatagaa agtatggatc agatgcaatc tatttacaat
      361 gaacgatcct ttcgaacgct taaacagtta ccaacgaatg aatacaaata tagttacgaa
      421 gaattcatga agcgcaggaa acaattccaa caaagagttg tcacgcaacg gagtttgcgt
      481 caattaaatc gaacgattaa tgcccatgaa gaaaaatacc acgcaagtaa agcctacgaa
      541 gagcaacaac gaagaattca aatggaacaa gaaagacagt aaagacagta ggaggaatag
      601 caatgaaaca atatttagat caatggaaag ttatagaagg atcattaaga gaagaacgaa
      661 tcgaacaact tcccgattgt ttagaaaaag agcatttgtt tcagataaga gaaatgttga
      721 gaaacgaaca gtttgatcca aatcaatttt tagtcgttga gtactcagct actggtgtgt
      781 actgttgtaa tcatgtgaag ggtgaaaaat attttatcat tcaagaatat gagggcaagt
      841 tagcgcctta ttatactact tgggaaatga atgaagaggg gatcaataac ttcccgtgta
      901 aaagcattga agagtctatt tcactcacag aatgttagtt gttaagtgaa taaaagaagt
      961 aaaagagtcc tgaacgtaat tgtccaggac tctttttttc aatgaattgt tttccgccaa
     1021 ttcaatgagt ggtgcgattt gcgactacat tatatcaaaa gaaagagaag ggaggaagaa
     1081 gaaatggctt attcaacgat tggagttgtt gttgaaaaaa gcagagacaa tctcgttttt
     1141 gtgacagaaa ttcaaacggg cagagctttt gtcgtcacag acaaagcggc aaaagcgtat
     1201 caaagtggcg atattttaac gttaaatctg actacgaaga cgttcgtcga tgcggcagaa
     1261 gattatccat t
//
LOCUS       DAXLPY010000186         1266 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.196, whole genome shotgun sequence.
ACCESSION   DAXLPY010000186 DAXLPY010000000
VERSION     DAXLPY010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.196"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            26..148
                     /locus_tag="ACF3UF_002824"
     CDS             26..148
                     /locus_tag="ACF3UF_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFD3672857.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            166..>1266
                     /locus_tag="ACF3UF_002825"
     CDS             166..>1266
                     /locus_tag="ACF3UF_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3672858.1"
                     /translation="MKKISVGLVGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDE"
BASE COUNT          492 a          170 c          282 g          322 t
ORIGIN      
        1 aagtattgat tgggggtaat ttctaatgga gaaaacggat atatctagtg catatcgacg
       61 acttaaaagc ccgaatatta aaactagaaa aagggcatta aaaattatca aagaacataa
      121 acgaaataaa atgaagaaat tagcataatt aaggaaggaa aaagaatgaa gaaaatcagt
      181 gtaggacttg ttgggatagc agctctagga ttattgggag cttgctccag cactaatgat
      241 gcaaaagtat cgaatgataa agatggaaaa ttagaaattg taacaacatt ctatccaatg
      301 tatgatttca ccaaaaacat cgtcggcgat gaagcgaacg tggatttaat ggttccagcg
      361 ggatcagaac ctcatgacta tgagccctca gctaaggata tggcaaaagc tcatgatgct
      421 gatgtttttg tatatcataa cgaaaacatg gaatcatggg taccaaaagc taaagaaagt
      481 tggaagaaag ctgggcctaa tgtagtagaa ggaacaaaag acatgatttt attgccaggt
      541 agtgaagaag aagatcatga tcacggagaa gaagatcacc atcatgaact agatcctcat
      601 acgtgggttt cacccaaaat ggcaattaag gaagtttcaa atatcaagga tcagttagtt
      661 aaattgtatc cgaaaaaagc aaaagtattt gagacaaatg ctgaaaagta tttgactaaa
      721 ctgaaacggt tggatgctga ctataccact agtcttaaag aagcgaaaca aaaaagtttt
      781 gtgacgcaac acgcagcctt tggatattta gctttggatt atggattgaa acaagttcct
      841 attgctggac taagtcctga agaagagcca tcttctggtc gattagctga attaaaagag
      901 tatgttaaaa aaaataagat caattatatt tactttgaaa agaatgctaa tgataaaatt
      961 gcaaaaactt tggccaacga agctgggata aaattggaag tactgaatcc tcttgaaagt
     1021 cttacaaaag aacaaatgga taatggtgaa gattatgttt cagtaatgga agacaatcta
     1081 aaagcgttag aaaaaacaac tatggttgct ggtgaagagg tagttccaga aaaagaagcg
     1141 aaggatgaaa agacagttgc taatgggtac tttaaagatg ccgatgtgaa ggatcgcgaa
     1201 ttgagtgatt atacaggcga atggcaatct gtttatccgt tgttaaaaga tggaattttg
     1261 gatgaa
//
LOCUS       DAXLPY010000187         1247 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.197, whole genome shotgun sequence.
ACCESSION   DAXLPY010000187 DAXLPY010000000
VERSION     DAXLPY010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.197"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>1247
                     /locus_tag="ACF3UF_002826"
     CDS             <1..>1247
                     /locus_tag="ACF3UF_002826"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFD3672859.1"
                     /translation="LSDSNYEVILIDKKSEISYLECGTSLFIKGEVSNLEDLFYQNRM
                     TLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQEYDKVILATGSKQIMLDIPGN
                     NLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYIGVEIAEAIRKRGKEVYLFDVA
                     DRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYLGRKKIEKIVTTSGTQYSMDMV
                     VQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKDIYAIGDCATTFFTSINRSSVD
                     FSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFNYNFYAAGLNLKTARLLSESID
                     YIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQLCSQEDLSGLLSMFSLAIEEQI
                     TLDKLKMLDYLFHPSFSQPYNFI"
BASE COUNT          484 a          146 c          210 g          407 t
ORIGIN      
        1 acttaagcga ttcaaattat gaagttattc taatcgataa aaaatcagaa attagttact
       61 tggaatgtgg gacatcgtta tttataaaag gagaagtaag taatttagaa gatctttttt
      121 atcaaaatag aatgacacta aattctgaga taaaaaagtt atttctagag acagaagttg
      181 acaaaattga tattcaaaat aaaaagatta gttgtgtaaa aaaagatggt acaagattct
      241 ctcaagaata tgacaaagtt atattagcta caggttcaaa gcaaattatg ctagatatac
      301 cggggaataa tttagctaat attttttcga taaagaattt tccaaatgca aaagagattt
      361 ttaaagcttt ggatgatagt actattaaaa aagtaggaat tattggagca ggatatattg
      421 gagttgaaat tgctgaagcc ataagaaaaa gagggaaaga agtatatctt ttcgatgttg
      481 cagatagagt gttgtcgact tattacgacc gtagtttttc agataaagtt gaagaaatac
      541 tatcaaaaaa tggaatacat ctttgtctat cagaaagtcc taaaaaatat ttaggaagaa
      601 aaaagattga aaaaatagtc actacaagtg gtacccaata ctctatggat atggtcgtac
      661 aagctatagg atttctatct aatagtccaa ttggggaaaa ggaactcttg agagatgtta
      721 gtggagcata tctaactaat gaataccagc aaacaaatat aaaagatata tatgctattg
      781 gggattgtgc tacaactttt tttacgtcca ttaatagaag tagtgttgat ttttctattt
      841 ctaatgctct aagaacagct tatattgcaa ctcaacatat taacaatcaa gattttacac
      901 cttctggttc ccaatttaca aatggctttt ctatatttaa ttacaatttt tacgcagcag
      961 gtttgaattt aaaaacagca cgattattaa gtgagtctat agattatata gaaatagaag
     1021 atttcattag acctgctttt ttgagaaaaa atagtcgtgt aaaattaaga attagctttg
     1081 aaaaaaatac aaagagaata gtaggtgtac aactttgtag tcaagaagat ttatctggac
     1141 tattatcaat gttttctctt gctatagaag aacaaattac attagacaaa ttgaaaatgt
     1201 tagattattt atttcatcct agttttagcc aaccctataa ttttatt
//
LOCUS       DAXLPY010000188         1236 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.198, whole genome shotgun sequence.
ACCESSION   DAXLPY010000188 DAXLPY010000000
VERSION     DAXLPY010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.198"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>1236
                     /locus_tag="ACF3UF_002827"
     CDS             <1..>1236
                     /locus_tag="ACF3UF_002827"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HFD3672860.1"
                     /translation="IENFKKEPFFEVEASIKVNQGSFKGVLSPTQRFKTQEELLAFVS
                     SKQAKIGNQEGIIADVQTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYE
                     AKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHH
                     AIIPTKQVPTESALAKMDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQS
                     IGKTPKQEGWKILFKQQTKEEKEDVQTLPLVIIGERAEVGVKSVEKETQPPKAFTEGT
                     LLTAMKTANKTVDDEEAIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEK
                     GKLLCQAVESQHLLTSAEMTAKWETYLKKIGKREGNQENFITNIKKFIVHLLEAVPND
                     IEKLNFSDYQEQKEKEAEKS"
BASE COUNT          485 a          192 c          252 g          307 t
ORIGIN      
        1 atagagaatt ttaaaaaaga accttttttc gaggtggaag ctagtataaa agtaaaccaa
       61 gggtcgttta agggcgttct aagccccaca cagcgtttta aaacccaaga ggagctttta
      121 gcttttgttt cttctaaaca agctaaaata ggcaatcaag aggggataat tgctgatgtt
      181 caaaccaaag agaagaaaac gaatagtccg agtttgtttt ctttaagtag tttgcaatca
      241 aaagtcaatc agctttataa agcgacagcg agccaaactt taaaagctat gcaaggactg
      301 tatgaagcaa aattattgag ttatccaaga acagatacac catttattac agagaacgaa
      361 tttgcttatt taaaagcaaa ttttggcaaa tatagcggtt ttttaggact tgatctcgaa
      421 atggttcaaa cagagcctag aaagcgttat gtggacggta gtaaggtaca ggaacaccac
      481 gccattatcc caacaaaaca agtacctacc gaatctgcat tagcaaaaat ggacgattta
      541 caacgaaaaa tatatgcttt agtcgttaaa acgaccgttg ccatgttttt acctgattac
      601 ttgtatgaag aaaccaagat acaaacgaaa gtagctgatt tgctgtttca atcgatcgga
      661 aagacaccaa agcaagaagg gtggaaaatt cttttcaaac aacaaaccaa agaagaaaaa
      721 gaggacgttc aaacgttacc actcgttatc attggcgaac gtgccgaagt tggtgttaag
      781 agtgttgaaa aagaaacgca accgccaaaa gcttttacag agggtacatt attaactgct
      841 atgaaaacgg cgaataaaac ggttgatgat gaagaagcaa tcaagatttt acaagaagtt
      901 gaggggattg gaacagaagc gacaagagca agtattattg aagcgttaaa acaaaaagaa
      961 tatatccaag tgattaagaa taagcttgtt gtaactgaaa aaggaaaatt attgtgccag
     1021 gcagttgaaa gtcagcacct tttaacgagt gctgaaatga cggctaaatg ggaaacgtat
     1081 ttaaaaaaaa tcggtaaaag agaaggcaat caagagaact ttattacgaa tatcaaaaaa
     1141 ttcattgttc atttactgga agctgtacct aacgatatag aaaaactaaa tttttctgat
     1201 taccaggaac agaaagaaaa agaagcagaa aaaagt
//
LOCUS       DAXLPY010000189         1190 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.199, whole genome shotgun sequence.
ACCESSION   DAXLPY010000189 DAXLPY010000000
VERSION     DAXLPY010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.199"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            143..400
                     /locus_tag="ACF3UF_002828"
     CDS             143..400
                     /locus_tag="ACF3UF_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672861.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1063)
                     /locus_tag="ACF3UF_002829"
     CDS             complement(632..1063)
                     /locus_tag="ACF3UF_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HFD3672862.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          438 t
ORIGIN      
        1 ttttctgtcc acgttcattt tactccaaag ttttcctcat ttcaaaagaa aatcacagaa
       61 tacacgaaga agcgtttcta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt attactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacata ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggg atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctctccaat cattttatta aaatcattaa
     1081 caaaaatatt ataataggat ttaagtaagt tctaactaat cacatataaa aataaaaaaa
     1141 catttgtatt ttatcaaagt tttattatac ttgtcaattt gtgtacatcc
//
LOCUS       DAXLPY010000190         1181 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.200, whole genome shotgun sequence.
ACCESSION   DAXLPY010000190 DAXLPY010000000
VERSION     DAXLPY010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.200"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..313
                     /locus_tag="ACF3UF_002830"
     CDS             <1..313
                     /locus_tag="ACF3UF_002830"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3672863.1"
                     /translation="YQDDKCVGKVKLRKNWNRYAYIEDIAVCKDFRGQGIGSALINIS
                     IEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDTMLYANFENNFEKAVFWYLR
                     F"
     gene            406..>1181
                     /locus_tag="ACF3UF_002831"
                     /note="aph(3')-IIIa"
     CDS             406..>1181
                     /locus_tag="ACF3UF_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFD3672864.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYI"
BASE COUNT          380 a          203 c          297 g          301 t
ORIGIN      
        1 ctaccaagac gataaatgcg tcggaaaagt taaactgcga aaaaattgga accggtacgc
       61 ttatatagaa gatatcgccg tatgtaagga tttcaggggg caaggcatag gcagcgcgct
      121 tatcaatata tctatagaat gggcaaagca taaaaacttg catggactaa tgcttgaaac
      181 ccaggacaat aaccttatag cttgtaaatt ctatcataat tgtggtttca aaatcggctc
      241 cgtcgatact atgttatacg ccaactttga aaacaacttt gaaaaagctg ttttctggta
      301 tttaaggttt tagaatgcaa ggaacagtga attggagttc gtcttgttat aattagcttc
      361 ttggggtatc tttaaatact gtagaaaaga ggaaggaaat aataaatggc taaaatgaga
      421 atatcaccgg aattgaaaaa actgatcgaa aaataccgct gcgtaaaaga tacggaagga
      481 atgtctcctg ctaaggtata taagctggtg ggagaaaatg aaaacctata tttaaaaatg
      541 acggacagcc ggtataaagg gaccacctat gatgtggaac gggaaaagga catgatgcta
      601 tggctggaag gaaagctgcc tgttccaaag gtcctgcact ttgaacggca tgatggctgg
      661 agcaatctgc tcatgagtga ggccgatggc gtcctttgct cggaagagta tgaagatgaa
      721 caaagccctg aaaagattat cgagctgtat gcggagtgca tcaggctctt tcactccatc
      781 gacatatcgg attgtcccta tacgaatagc ttagacagcc gcttagccga attggattac
      841 ttactgaata acgatctggc cgatgtggat tgcgaaaact gggaagaaga cactccattt
      901 aaagatccgc gcgagctgta tgatttttta aagacggaaa agcccgaaga ggaacttgtc
      961 ttttcccacg gcgacctggg agacagcaac atctttgtga aagatggcaa agtaagtggc
     1021 tttattgatc ttgggagaag cggcagggcg gacaagtggt atgacattgc cttctgcgtc
     1081 cggtcgatca gggaggatat cggggaagaa cagtatgtcg agctattttt tgacttactg
     1141 gggatcaagc ctgattggga gaaaataaaa tattatattt t
//
LOCUS       DAXLPY010000191         1133 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.201, whole genome shotgun sequence.
ACCESSION   DAXLPY010000191 DAXLPY010000000
VERSION     DAXLPY010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.201"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>1133
                     /locus_tag="ACF3UF_002832"
     rRNA            <1..>1133
                     /locus_tag="ACF3UF_002832"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          290 a          256 c          350 g          237 t
ORIGIN      
        1 agagaatcct aaggtgagcg agagaactct cgttaaggaa ctcggcaaaa tgaccccgta
       61 acttcgggag aaggggtgct gatcatacga tcagccgcag tgaataggcc caagcgactg
      121 tttatcaaaa acacaggtct ctgcaaaatc gtaagatgaa gtataggggc tgacgcctgc
      181 ccggtgctgg aaggttaaga ggagtgctta gcgcaagcga aggtacgaat tgaagcccca
      241 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
      301 ccgacccgca cgaaaggcgt aacgatttgg gcactgtctc aacgagagac tcggtgaaat
      361 tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc atggagcttt
      421 actgtagttt gatattgagt gtctgtaccg catgtacagg ataggtagga gccgtagaaa
      481 tcggaacgct agtttcgatg gaggcgctgg tgggatacta cccctgcgtt atggccactc
      541 taacccgcac cactaatcgt ggtgggagac agtgtcagat gggcagtttg actggggcgg
      601 tcgcctccta aaaggtaacg gaggcgccca aaggttccct cagaatggtt ggaaatcatt
      661 cgaagagtgt aaaggcagaa gggagcttga ctgcgagacc aacaagtcga gcagggacga
      721 aagtcgggct tagtgatccg gtggttccgc atggaagggc catcgctcaa cggataaaag
      781 ctaccctggg gataacaggc ttatctcccc caagagtcca catcgacggg gaggtttggc
      841 acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc
      901 gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc
      961 cgtcgcgggc gttggaaatt tgagaggagc tgtccttagt acgagaggac cgggatggac
     1021 ttaccgctgg tgtaccagtt gttctgccaa gggcattgct gggtagctat gtagggaagg
     1081 gataaacgct gaaagcatct aagtgtgaag cccacctcaa gatgagattt ccc
//
LOCUS       DAXLPY010000192         1109 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.202, whole genome shotgun sequence.
ACCESSION   DAXLPY010000192 DAXLPY010000000
VERSION     DAXLPY010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.202"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            2..412
                     /locus_tag="ACF3UF_002833"
     CDS             2..412
                     /locus_tag="ACF3UF_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3672865.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            426..782
                     /locus_tag="ACF3UF_002834"
     CDS             426..782
                     /locus_tag="ACF3UF_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3672866.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          384 a          167 c          212 g          346 t
ORIGIN      
        1 aatgataaaa gtatatactt cgcctagctg tacttcctgt agaaaagcaa gagcatggtt
       61 gcaagcgaat caacttgaat ttgaagagaa gaatattttt gccgaaccgt taacagaaag
      121 tgagatcaaa aagatcttgg cagcgactga aggaggagtt caagatatta tttccactcg
      181 gtcgaaaatt tacgaaaagc tgggcataga ttttaacgaa ttaactttaa agcaaatgat
      241 cgtcttattc aaagaatatc cttcattatt gagacgacct attttgattg atgaaaaaag
      301 aatactaatc ggatttaatg aagatgagat ccggtcattt gtccctcgtg aaattcgatg
      361 tgttgccaga aatctgatct atttacaaaa caataacatc ttaaattcat agggagggag
      421 ccttcgtgga agtgaaagtc tatggatcag cgcactgtgt aacaagtctg aaggcgaaac
      481 aatggttaga acaccatcaa ttgccttatc aatttgttga cttagaagaa cgcgatctaa
      541 gtacagaaga agcagaagaa ttatgcagtt ttgaagaagt gcaagcagaa cagctatttg
      601 cgacttggtc tgaggctttt cacaacattg cgattgacct ttcctgtgta ggaaaaaaac
      661 aactgatttt tttatgcaca caacatacca atctcctcag acgtcctttg attattatcg
      721 atgaagttct atttattgga tacaatgagc agttgatgga acagcttatc ttaaataaat
      781 agactttaac tgttttaatc aagtcactga gcatttcata cagttgtaac agtcgaacac
      841 ttagcatcaa gcgtgttatg tgttcttttt ttgactttat ttttctacta tagagacatg
      901 ctcaatttat agagacatgc tcaatttatg tggtcaaaat tcaaatctag gtggggatat
      961 agagttaaaa atatattgac atgtgtaaat ttacatgata tattcatttc tgttgtttta
     1021 agtagcaaag caataaaata gtattttaaa aaacatataa aatagttgtt gacatgttgg
     1081 aaatgacatg ataagataac tgagtcgtt
//
LOCUS       DAXLPY010000193         1106 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.203, whole genome shotgun sequence.
ACCESSION   DAXLPY010000193 DAXLPY010000000
VERSION     DAXLPY010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.203"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..330
                     /locus_tag="ACF3UF_002835"
     CDS             <1..330
                     /locus_tag="ACF3UF_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672867.1"
                     /translation="DFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLTNIENKGQQP
                     SFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVTIGKVIQAIY
                     GEKCKFN"
     gene            complement(844..1011)
                     /locus_tag="ACF3UF_002836"
     CDS             complement(844..1011)
                     /locus_tag="ACF3UF_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFD3672868.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
BASE COUNT          365 a          164 c          188 g          389 t
ORIGIN      
        1 gatttcaaac cattgggtct tgcgattaaa gaagcccgtc ttagtaaagg attgactcgt
       61 gagcaggtag gatcaatgat ccagattgcg ccacgctatt tgacgaacat tgaaaataaa
      121 ggacaacagc caagttttca tgttgtatat gatttagtga ctttgctaaa tatttctttg
      181 gatggattta ttttagggga agaaaacagt cataaaagct ccaaacgtct tcaagtagaa
      241 gcacagttgg attgtctgga tgaagatgaa ttagtgacga ttgggaaagt gattcaagca
      301 atttacggag aaaaatgtaa atttaactag ttcaataata cacaatggat taattaatac
      361 tatcaggaaa gattgattac aaagatgtaa tgaatttttt ctgatttttg ttaatcataa
      421 atagaaaatg aatttatctt tgttacactt aggaactaga gcgaatgata aatagttctt
      481 tggttactct tatcgctgca aagtacagtt cattttttgt tgttgggaaa attttctgga
      541 tttattgcat atcacttcat ccgactaaaa atttttgatt cccatagcga agttcgtttt
      601 tgttccttag gaaaaacttg actgatatac tagttttgaa atgacgagta actctgtact
      661 tcatcaataa tcaagtattg aattttaatt gtatactttt tatgcttgag ggatgtctac
      721 tgtaatacag ctactgcaaa aaaaatcagt acacttattt tcttataaag gatatcaaga
      781 actaagctca atggtatgca tagaaaagaa aaagccgata aaatgagatt ttgatatctc
      841 gaattatcgg ctctgcgtct ttgcgtctgg ctctgtaatt acagttattc taaacttcgt
      901 tatttcaatt aaaatttctt gtctgcattt aggacaaaat agagggaaat tttttaattc
      961 agtatcttcc ctcattttta aacgggtctt attgccacat atagggcaca gtatccacct
     1021 agtatttaca atatctatat cctcctgttc taattaacaa ctcaatattc attttaaaaa
     1081 tttctcttta gttcactatc aatgta
//
LOCUS       DAXLPY010000194         1081 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.204, whole genome shotgun sequence.
ACCESSION   DAXLPY010000194 DAXLPY010000000
VERSION     DAXLPY010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.204"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            118..1014
                     /locus_tag="ACF3UF_002837"
     CDS             118..1014
                     /locus_tag="ACF3UF_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFD3672869.1"
                     /translation="MIQYYYIKKEWGVVMEKEELKILEELRRILNSKNEAIVILNNYF
                     KGGVGKSKLSTMFAYLTDKFNLKVLMIDKDLQATLTKDLAKTFKVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLERIIQLENEKE"
BASE COUNT          414 a          155 c          178 g          334 t
ORIGIN      
        1 tctttttcaa aataaacata aaagcccttt aaagagggct tttatatatt aatcacaaat
       61 cacttatcac aaatcacaag tgattaatca caaatcactt gtgatttgtg attcctaatg
      121 atacaatatt actatataaa aaaagaatgg ggcgtagtta tggagaagga agaactaaaa
      181 atacttgaag aattaagacg tattttaaac agtaaaaatg aagcaattgt tatcttaaac
      241 aattatttta aaggtggtgt tggaaagtca aaattatcga ctatgtttgc ttatttgaca
      301 gacaaattta atttaaaagt tttaatgatc gataaggact tacaagcaac attgacaaaa
      361 gacttagcaa aaacatttaa ggtagaattg ccacgtgtca atttttatga aggcttgaaa
      421 aatggaaact tggcttcttc tattattcat ttgactgata atttagactt gatccctggc
      481 acgtttgatt tgatgttact gccaaaatta actcgctcat ggacgtttga aaacgaaagt
      541 agattgcttg ctactctttt agcaccttta aaaagtgact atgatctcat tattattgat
      601 actgtaccaa cgccaagcgt ttatacaaat aatgcaatcg tggcaagtga ttacgttatg
      661 atccctttac aagcagaaga agaaagtaca aacaacattc aaaactatat ttcctatttg
      721 attgatttac aagaacagtt taaccctgga ctagatatga tcggttttgt tccttattta
      781 gttgatacgg acagcgcaac gataaaatca aacctggaag aactgtacaa agaacataaa
      841 gaggataatt tggttttccg aaatattatc aagcgaagta ataaagtaag tacctggtct
      901 aaaaacggca ttacagaaca caaaggctat gacaaaaaag ttttatctat gtatgagaac
      961 gtattttttg aaatgcttga gcgaatcatt caattagaaa acgaaaaaga atagaatcac
     1021 aaatcacaag tgattaatca caaatcactt gtgatttgtg attgttgatg ataaaataag
     1081 a
//
LOCUS       DAXLPY010000195         1068 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.205, whole genome shotgun sequence.
ACCESSION   DAXLPY010000195 DAXLPY010000000
VERSION     DAXLPY010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.205"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..490)
                     /locus_tag="ACF3UF_002838"
     CDS             complement(<1..490)
                     /locus_tag="ACF3UF_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFD3672870.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVY"
     gene            complement(550..759)
                     /locus_tag="ACF3UF_002839"
     CDS             complement(550..759)
                     /locus_tag="ACF3UF_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672871.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            complement(826..1065)
                     /locus_tag="ACF3UF_002840"
     CDS             complement(826..1065)
                     /locus_tag="ACF3UF_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672872.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
BASE COUNT          293 a          239 c          140 g          396 t
ORIGIN      
        1 gatagacgcc atcgttacta actaagtcca tcacctcccc taatgacaac ttttgaatat
       61 cagaaaataa aacacctggc atttccatgt tatgacctgc taggacatag tttcctttgc
      121 ccatttcggc atcttcataa aaataagtag ccgctccaag actcaaagtg tattgatttg
      181 cccctttaaa aattggcaat gctaaaccaa gtgcaggaat ctgaatttgt gcaaatactt
      241 gtttattgac gcccatttcg attgcttctt tttgtatgga caacatttgc cccaaagaca
      301 tatcattatt gacgttcgtt gcatcctcct tataactctt tgcatgtgca ttgatttgat
      361 ctacgggcat ctttttttct atattttgct taaacacctc tccttcatgt ttttggtagc
      421 taacatagcc aaacacactg caaaagacga ttaaagtgac tcctaaaaaa ccaaataacc
      481 attttttcat ccatctgcct cctttcagac aaaacaaaaa aactttttct catttccata
      541 gaaaaagttt taaaaatgaa ttctataagt tcgtctcaac tgttcaaagt ttttcattga
      601 acctaacaaa caagctttct cttttcctgt taactgcata tcattgatat attgcgcgac
      661 agataatctt ttaaggtgtt tttgcttcat cgtttttagt aacttttctt ccatttcttt
      721 cgacactttt tttctgtttt cgatttcttc ataattcatg agttttccta ccttccttgt
      781 tttttgcaaa aataaaaaag cctatgatca catacgctct acacttcagt cttgggttat
      841 ctttttcttt cgtttaatta ctggccgtgc tggtttcaaa tccttgattc cattatgggt
      901 tctccaataa tcgaattctt ttcgcaatct ttctttttcc atatctgttc ctttagataa
      961 ggctttgaat acttctttag gtgaataacc acgagctaac agctgtacat accttccttt
     1021 tgtcaaagta tccatatcca tcgcctctaa aactggtcgc gccatcta
//
LOCUS       DAXLPY010000196         1063 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.206, whole genome shotgun sequence.
ACCESSION   DAXLPY010000196 DAXLPY010000000
VERSION     DAXLPY010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.206"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(37..>1063)
                     /locus_tag="ACF3UF_002841"
     CDS             complement(37..>1063)
                     /locus_tag="ACF3UF_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFD3672873.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          346 a          178 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aac
//
LOCUS       DAXLPY010000197         1041 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.207, whole genome shotgun sequence.
ACCESSION   DAXLPY010000197 DAXLPY010000000
VERSION     DAXLPY010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1041
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.207"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            228..>1041
                     /locus_tag="ACF3UF_002842"
     CDS             228..>1041
                     /locus_tag="ACF3UF_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672874.1"
                     /translation="MFTSCKEKRLKFAIRKKKGGGAASFIIGCLIFGNIFLNGAIANA
                     SSIENSYAISGFGNQTKGGYFLYNKGIKTESVIDNQVAFCFDKNVIAKLNDRGFSNPG
                     YQLYNEKDEQLLKVYSNEKINKVRNIMAYAWDNFITKYPYLNTYTAASNDDRASLARG
                     ISHAIWVTLGQTTEKKSRSDLGGVNTNAYKFYKEALNYKPLAKDINNYDISLLIPTDD
                     NNILQVNASQSLITVKKIDPDKPVNPDPETPVTPETPDPETPVTPETPDPETP"
BASE COUNT          378 a          151 c          177 g          335 t
ORIGIN      
        1 agcaaaatta gcattgatta cctgtctaat tttaatgttt tatagtgagt ctacctgaaa
       61 ataaaagtgc ctcatcataa ttgtttctta aaaaataaac gatcattttt ttattgaaat
      121 ttccggaaaa ttaatttata cttttatcga aaaacattct aatttgaatg ctttttcttt
      181 ttgtctataa aacatgaacg ttcattttgc ggtaaggaga gatgggaatg tttactagtt
      241 gtaaagaaaa aagattgaaa tttgcaatta gaaagaagaa aggtggtggt gctgcgtcct
      301 ttataattgg ctgtttaatt tttggaaaca tatttctcaa tggcgctatt gctaatgcgt
      361 ctagtataga aaatagttat gcaataagtg gttttggtaa tcagacaaaa ggtgggtatt
      421 tcttatataa taagggtatt aaaactgaaa gtgttattga taaccaagta gctttttgtt
      481 ttgacaaaaa cgttatagct aaactgaatg atcgtgggtt ttcaaaccct ggttatcaat
      541 tatacaatga aaaagacgaa caactcttga aagtatatag taatgaaaaa attaataaag
      601 taagaaatat catggcttac gcttgggata attttattac taaatatccc tatttaaata
      661 cttatacagc cgcttctaat gatgatcgtg cttctcttgc cagaggaatt agtcatgcta
      721 tttgggtaac cttgggacaa acaacagaga aaaaatcaag aagtgattta ggtggcgtaa
      781 atactaatgc ttataaattt tataaagaag ctctaaatta caagccactt gcaaaagata
      841 ttaacaatta tgatattagt ttacttattc caactgacga caataatatt ttgcaggtaa
      901 atgcttctca atcattaata acggttaaaa aaatcgatcc agataaacca gtaaatccag
      961 atccagaaac tccggtaacg ccagagactc cagatccaga aactccggta acacctgaga
     1021 ctccagatcc agaaactccg g
//
LOCUS       DAXLPY010000198          991 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.208, whole genome shotgun sequence.
ACCESSION   DAXLPY010000198 DAXLPY010000000
VERSION     DAXLPY010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.208"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(21..94)
                     /locus_tag="ACF3UF_002843"
     tRNA            complement(21..94)
                     /locus_tag="ACF3UF_002843"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="ACF3UF_002844"
     tRNA            complement(108..181)
                     /locus_tag="ACF3UF_002844"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="ACF3UF_002845"
     tRNA            complement(209..281)
                     /locus_tag="ACF3UF_002845"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="ACF3UF_002846"
     tRNA            complement(301..374)
                     /locus_tag="ACF3UF_002846"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="ACF3UF_002847"
     tRNA            complement(384..457)
                     /locus_tag="ACF3UF_002847"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="ACF3UF_002848"
     tRNA            complement(468..553)
                     /locus_tag="ACF3UF_002848"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="ACF3UF_002849"
     tRNA            complement(570..641)
                     /locus_tag="ACF3UF_002849"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="ACF3UF_002850"
     tRNA            complement(653..725)
                     /locus_tag="ACF3UF_002850"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="ACF3UF_002851"
     tRNA            complement(743..824)
                     /locus_tag="ACF3UF_002851"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="ACF3UF_002852"
     tRNA            complement(832..904)
                     /locus_tag="ACF3UF_002852"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="ACF3UF_002853"
     tRNA            complement(908..980)
                     /locus_tag="ACF3UF_002853"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          260 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact t
//
LOCUS       DAXLPY010000199          943 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.209, whole genome shotgun sequence.
ACCESSION   DAXLPY010000199 DAXLPY010000000
VERSION     DAXLPY010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.209"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            28..>943
                     /locus_tag="ACF3UF_002854"
     CDS             28..>943
                     /locus_tag="ACF3UF_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3672875.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEV"
BASE COUNT          327 a          163 c          176 g          277 t
ORIGIN      
        1 ccaaagaatt ataaggagtg agtacaaatg acctataccc atcttacaac ggatgaactt
       61 gtaataatag agtcttattt caaaatgaat caatctgttg ctaaaactgc ccattgcttg
      121 aatcgttcaa gacaaacgat ccataaagta tatctgttct tcaagcaagg aaaatcagcc
      181 ttagaatatt atcaacagta taagaaaaac aaatcaaact gtggtagacg tccgcttgtt
      241 ttacccgagg aacaatcaga atatattcaa agaaaggttg ttcaaggatg gacacccgat
      301 gtgattgttg gtcgtgcagc gtttcctatt agttgttctg ctcgtaccat ttatcgtatg
      361 ttcaaaaagg ggctatttga ttcttctgac ttaccgatga aaggcaagcg taaaccgaat
      421 ggacatcaag aaagacgtgg aaaacaaact ttccgccgct ctattcatga acgtgaaaag
      481 gattatagcc aattctcaaa tgagtttggt caccttgaag gtgacactat cgtaggtctg
      541 aaacataaaa gtgctgtaat taccttagtt gaacgattat caaaagttat catcacattg
      601 aaaccgtgtg gtagacaagc gattgatatt gaaaaaaaat taaatcaatg gtttgaatct
      661 gtaccgaaaa acctattcaa atccatcact tttgattgtg gaaaggaatt ttcaaattgg
      721 aaacagatca gtaatgtcaa tgatattgcc atttatttcg ctgatccagg aacgccgtct
      781 caaagaggcc taaacgagaa ttctaacgga ttgttacgta gagatggttt attgaaatct
      841 atggatttca attcagtaga tgaatttttt attcaatctg tcgcatctaa acgaaataat
      901 attcctagaa aatcactgga ttatcgaaca cctttggaag tat
//
LOCUS       DAXLPY010000200          941 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.210, whole genome shotgun sequence.
ACCESSION   DAXLPY010000200 DAXLPY010000000
VERSION     DAXLPY010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.210"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            26..>941
                     /locus_tag="ACF3UF_002855"
     CDS             26..>941
                     /locus_tag="ACF3UF_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3672876.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEV"
BASE COUNT          339 a          170 c          180 g          252 t
ORIGIN      
        1 aaagaattat aaggagtgag tacaaatgac ctataaccat cttacaccaa ctgaactcgt
       61 aatgatagaa gcttatttca atcaatcaca acctgtttca aaagtagcca atctgttaca
      121 acgttctcga caaactattt ataaggtcta tcgttttctt aaatctggtg gaagcgcaat
      181 gagctactat aaacaatata agaaaaacaa acgtaactgc ggaagacatc cgattgtttt
      241 acctgatgag caacaggaat acattcaaaa aaaggttgtt caagggtggg ctcctgatgt
      301 ccttattggt cgagcagagt ttcctattgc ttgttcggta cgcacactgt atcgaatgtt
      361 taaagataaa acctttgaca ctcacgattt accaatgaag ggaaaaagaa aaccaaacgg
      421 tcataaagaa aaaagaggaa aacaagggtt tcgccggtca atccgagaca gaaagacaga
      481 ctatacccag tttgatcatg aatttggtca cctggaaggt gacactatcg tgggtggaaa
      541 acataaaagc gcggtcatca cattagttga acggctatct aaagtcatca ttaccttgaa
      601 acccgaaggc agacaggcta aagacattga aaataggctg aatcaatggt ttcgttgtgt
      661 cccaaaaaac ttatttaaat ccatcacatt tgattgtgga aaagaattct caaattggaa
      721 aaagattagt aataccaacg atatttcaat ttattttgcg gatccaggaa caccttctca
      781 acgaggattg aatgaacatt caaatggctt attacgtaaa gatggtttgt ataaagctat
      841 ggattttaat ggtgtatctg aaacctttat ccaatcggtg gcatcgaaac gaaatcatat
      901 tcctagaaaa tcattacact atcggacacc aatggaagta t
//
LOCUS       DAXLPY010000201          940 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.211, whole genome shotgun sequence.
ACCESSION   DAXLPY010000201 DAXLPY010000000
VERSION     DAXLPY010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.211"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            25..>940
                     /locus_tag="ACF3UF_002856"
     CDS             25..>940
                     /locus_tag="ACF3UF_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3672877.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEV"
BASE COUNT          332 a          174 c          179 g          255 t
ORIGIN      
        1 aagaattata aggagtgagt gcaaatgacc tatacccatc ttacaccaac tgaactcgta
       61 atgatagaag cttatttcaa tcaatcacac tctgtttcaa aagtagccca tctggtacaa
      121 cgttctcgac aaaccattta taatgtctat cgttttctta aatctggtgg aagcgcaata
      181 agctactatg aacaatataa gaaaaacaaa cgtaactgcg gaagacgtcc gattgtgtta
      241 ccagatgggc aacaagaata cattcaaaaa aaggtggctc aagggtggac tccagatgtc
      301 cttattggtc gagcagagtt tcctattgct tgttcggtac gtacactata tcggatgttt
      361 aaagataaaa cctttgaccc tcacgattta ccaatgaaag ggaaaagaaa accaaacgga
      421 cataaagaaa aaagaggaaa acaagctttt cgccgttcga ttcaggatag aacaactgat
      481 tatatacagt tcaatcatga gtttggtcac ctagaaggtg acaccattgt cggtggaaaa
      541 cataaaagtg cggtgatcac gttagttgag cgattatcta aagtgatcat caccttgaaa
      601 cccgctggta ggcaagctat agatattgag aatagactga atcaatggtt tcaatctgta
      661 ccgaaacact tgtttaaatc catcacattt gattgtggaa aagagttctc gaattggaaa
      721 aagattagta ataccaatga tatttcgatt tatttcgctg atccaggaac accttctcaa
      781 cgaggactaa atgaacattc gaatggctta ttacgtaaag atggcttata taaagctatg
      841 gattttaata aggtatccga aacctttatc caatcggtgg catcaaaacg aaatcatatt
      901 cctagaaaat cattacacta tcgcacacca ttggaagtat
//
LOCUS       DAXLPY010000202          905 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.212, whole genome shotgun sequence.
ACCESSION   DAXLPY010000202 DAXLPY010000000
VERSION     DAXLPY010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.212"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            3..581
                     /locus_tag="ACF3UF_002857"
     CDS             3..581
                     /locus_tag="ACF3UF_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3672878.1"
                     /translation="MDNKTNNTKTEIKKNDISKASEAIKGELVFEDKVIQKIIGIALD
                     EIDGLLTVDGGFFSNIAGKLVNTDNTTSGVDVEVGKKQVAVDLSIVAEYGKDVTTIYD
                     KIKQVISNEVRKMTGLDVIEINVNVVDVKTKEQYEKDSVTLQDHLTDAASATGEFASK
                     QIEKSKEALGVASEKVNDGVQNVKEATEPRVK"
BASE COUNT          364 a          102 c          153 g          286 t
ORIGIN      
        1 taatggataa taaaacaaac aatacaaaaa cagaaattaa aaagaatgat atatcaaaag
       61 cttctgaagc tattaaagga gaattggttt ttgaagataa agtaattcaa aaaataatcg
      121 gtattgcatt agatgaaatt gatgggcttt tgacagttga tggaggattc ttttcaaata
      181 tagccggaaa attagtaaat acagataaca caacttctgg agtcgatgtt gaagtaggta
      241 aaaaacaagt tgcagtagat ctttcaatag tggctgaata tggtaaagat gtaactacaa
      301 tttatgataa aattaagcaa gtaatctcaa atgaagttag gaaaatgact ggcttagatg
      361 taattgaaat taacgtaaac gtcgtagatg taaaaacaaa agaacaatac gaaaaagatt
      421 cagttaccct acaagatcat cttactgatg cagcttctgc tactggagaa tttgcttcaa
      481 aacaaattga gaaatcaaaa gaagctttag gagtagcaag tgaaaaagtt aatgatggtg
      541 tacaaaacgt aaaagaagca acagaacctc gtgtaaaata gtaacttcct ttctgtaata
      601 tacaacatat aaaattgaaa gactaaattt aaggctctta gatattttaa tgtagatata
      661 gaagaaagaa ctgaaatata ataaaaccag ttaggtatag gacttaactg gttttagttt
      721 ctttaagtgg gagatcaaca tctgaataag cattttgtga aagatgtaga aatctttata
      781 gctgttggtt actcattttg tatttcttat ttagttcttt tgtctctttc tagtaaatct
      841 ttacaatatt ttagttctca atttatatta tttaaaaatt ttattatcgt ataaaccatt
      901 ataaa
//
LOCUS       DAXLPY010000203          876 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.213, whole genome shotgun sequence.
ACCESSION   DAXLPY010000203 DAXLPY010000000
VERSION     DAXLPY010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.213"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            4..>876
                     /gene="bsh"
                     /locus_tag="ACF3UF_002858"
     CDS             4..>876
                     /gene="bsh"
                     /locus_tag="ACF3UF_002858"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFD3672879.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYED"
BASE COUNT          296 a          118 c          160 g          302 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagttact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaaactaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgatgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagac
//
LOCUS       DAXLPY010000204          854 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.214, whole genome shotgun sequence.
ACCESSION   DAXLPY010000204 DAXLPY010000000
VERSION     DAXLPY010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.214"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..767)
                     /locus_tag="ACF3UF_002859"
     CDS             complement(<1..767)
                     /locus_tag="ACF3UF_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFD3672880.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRC"
BASE COUNT          246 a          188 c          146 g          274 t
ORIGIN      
        1 tggcatcttt gccagctcgc acctaaaaag ttcttgcgaa cagccttaac taaccctttg
       61 tgtgcatcag aaatgaccag ttttacaccg aacaaacctc gttgaacgaa cgattgaaaa
      121 acggtatccc aattatcttc cgattcgccg tcttgaacat caaaaccaag aatcgtacgt
      181 cgtccatcag aatcaatgcc gataccaata tatacacctt ttgagacaat acgatgattt
      241 tcccttactt tcatatacag ggcatcacac atgaaaaatg gatattccga gccttctagg
      301 ctccggtttc tccactcaaa aacaaatgga tccaactgtt tcatcagatt tgaaacgaat
      361 gatttagaaa cagtcgcacc atccgttagc agttcaactg ttttagttac tttgcgagtg
      421 gagacaccag aaatgaccat ttcaatcatg gcagcgatca aagctttttc gcttcgctga
      481 tatctttcaa agatagtagg actaaactta ccgtctctgg ttcgtggaac atgaagttct
      541 aacgtaccaa ttcgagttgt aaacgaacga tcgtagtaac catttctttg tgattgccgt
      601 tcttctgaac gttcataggc atttgcctga atatattgat ttcgttgttc ttccatcagc
      661 tgattaaaca tgatagtcat aagtgttttt gcggtatcat tcgcaccgct ttcgtttata
      721 attgcttgaa tttcttcgct ttcaaaagta aaatgtactt gagtcattga tatcagtcct
      781 attcgagtat gttttctgca aaaaacattg tactcctaac tgagatcaat ggcttttttg
      841 atgcttcact ttta
//
LOCUS       DAXLPY010000205          813 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.215, whole genome shotgun sequence.
ACCESSION   DAXLPY010000205 DAXLPY010000000
VERSION     DAXLPY010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.215"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..533
                     /locus_tag="ACF3UF_002860"
     CDS             <1..533
                     /locus_tag="ACF3UF_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFD3672881.1"
                     /translation="ALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLV
                     IVVLFFKELLITSFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLI
                     TPAATAYLYANSLKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISF
                     LISPKQKFLRKKERSL"
     gene            533..>813
                     /locus_tag="ACF3UF_002861"
     CDS             533..>813
                     /locus_tag="ACF3UF_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3672882.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFY"
BASE COUNT          276 a          102 c          151 g          284 t
ORIGIN      
        1 tagcactagg agttatcctt ataggagttg caaatagctc aacggattta tttcatattt
       61 tatttggaaa tattttagct gtacaagata ttgataagtg gattacaatt ggcgtttcgg
      121 ttttagtgtt ggttatagta gttctatttt ttaaagaatt attaatcact tcttttgatc
      181 cattaatggc aaaagcaata gggatgaatg tcagttttta tcattatcta ttgatggttc
      241 tattaacttt agtagcagta acagctatgc aaagtgtggg aactatatta attgttgcaa
      301 tgttaattac accagcagct acagcatatt tatatgcaaa tagcttgaaa actatgatat
      361 ttatttctgc aacagtcgga gcaagttcat cattgcttgg attgtttatt ggttatagtt
      421 ttaacatagc agcaggatca agtattgttt taacagcggc attcttattt gtaattagtt
      481 ttctaatctc accaaaacaa aaatttttaa gaaagaagga gagatcgtta tgatgagaaa
      541 atggaaagca gtactgggaa gtctggggat tttgattgct ctttttatat tcggggcatg
      601 ttcaataaat agtaaagaca aagataaagt ggcttcgaac gaaaaattaa aagtagtagt
      661 tactaattcg attttagcag atattaccga aaatatagca aaagataaaa ttgatttaca
      721 cagtatcgta cctattggga aagatcccca cgaatatgaa cctttgcctg aagatgttca
      781 aaaaacttca aaagcagatt tgatttttta taa
//
LOCUS       DAXLPY010000206          773 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.218, whole genome shotgun sequence.
ACCESSION   DAXLPY010000206 DAXLPY010000000
VERSION     DAXLPY010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.218"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>773
                     /locus_tag="ACF3UF_002862"
     CDS             <1..>773
                     /locus_tag="ACF3UF_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFD3672883.1"
                     /translation="CMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGIADPQPI
                     IQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRKQNLNLS
                     ALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENHYNGKYY
                     HQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQDFIVAM
                     QEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDK"
BASE COUNT          294 a          131 c          119 g          229 t
ORIGIN      
        1 atgtatgtgt tgcagtcttc gcagtgattt attagcaata ttgatttctt tactggaaac
       61 aatagaagaa catcaacaac caatttcaca aatcatcatt gaaactacag gtatagcaga
      121 tccccaacca atcattcaaa cacttttaac agcgcctcaa ctaagaggaa gagtatatat
      181 cgatagttta ttgactgtta ttgatagtga cagttttgaa cttattgaaa gagaaccaca
      241 agcccttaag caacttgtca tggcagatcg catttttgtg tctagaaaac aaaacttgaa
      301 tttatctgca ctaaaaaaat tacagagaga aatcaaaagt attaaccctt tatccgatat
      361 tcgaatgttc acacatagtg aaacgattca aaaaaaggat ttttataatt tgaaaaaatt
      421 taatcatccc ttagtttttg aaagtgattc atcagaaaat cactataatg gcaaatacta
      481 tcatcaacac catcaagtac atgagtttaa atcaattctc ttaacttcag atcaagacat
      541 aaaaaaagat tttttactcc aatggattga ctggctgatt ttaaccaacc aagggagcct
      601 gtatcgtttt aaaggattga ttgctttaca agagcaggat tttatagttg ccatgcaaga
      661 ggtaaacgaa caggttaatt ttcaatacac cactcgacaa aaagaccaaa ccactattat
      721 tctaatcgga aaaatgttgg atgaagaaag gatcaaacag agttttgata aat
//
LOCUS       DAXLPY010000207          769 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.219, whole genome shotgun sequence.
ACCESSION   DAXLPY010000207 DAXLPY010000000
VERSION     DAXLPY010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.219"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(152..346)
                     /locus_tag="ACF3UF_002863"
     CDS             complement(152..346)
                     /locus_tag="ACF3UF_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672884.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
     gene            594..>769
                     /locus_tag="ACF3UF_002864"
     CDS             594..>769
                     /locus_tag="ACF3UF_002864"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3672885.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEA"
BASE COUNT          251 a          151 c          138 g          229 t
ORIGIN      
        1 tgtgatagag aaataacaat ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat
       61 ttgattttga tcgggtctag tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc
      121 ttaaatttca tcttgactta tcaccattag actaaacaaa tggataatct tctgtcgcat
      181 cgacgaacgt cttcgtagtc agatttaacg ttaaaatatc gctactttga taagcttttg
      241 ccgctttgtc tgtgacgaca aaagatctgc ctgtttgaat ttctgtcaca aaaacgagat
      301 tgtctctgct tttttcaaca acaactccaa tcgttgaatg aaccatttct gcttcctccc
      361 ttctctttct tttgatataa tgtagtcgca aatcgcacca ctcaatgagt tggcggaaaa
      421 caattcattg aaaaaaagag tcctggacaa tcacgttcag gactctttta cttcttttat
      481 tcacttaaca actaacactc tgtgagtgaa atggactctt caatgtgatg ttaggatgat
      541 ttcatggaca cgatttggta gaatctaact actaagaaaa ggacgtgtcc acgatggcaa
      601 aagccaagaa aaaatttgat gaagacttta agaagatgat cttagattta aaccagtctg
      661 gccaatcggt cgaagaactg gcagcgcaat atggtatcgc tacacaaacg atttatcgtt
      721 ggaagaagct tcatacaaag aatgtagcaa ccggcatgac tgaggcaga
//
LOCUS       DAXLPY010000208          768 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.220, whole genome shotgun sequence.
ACCESSION   DAXLPY010000208 DAXLPY010000000
VERSION     DAXLPY010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.220"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            2..>768
                     /locus_tag="ACF3UF_002865"
     CDS             2..>768
                     /locus_tag="ACF3UF_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672886.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVT"
BASE COUNT          329 a          116 c          173 g          150 t
ORIGIN      
        1 catggcagaa gaaaaagaac cactagacaa tagtcgcttg ggaaaatcca aaagaaaatt
       61 agtacgattg caaaatgaat taaacgaaca aattgagaag atgtttgaac accagagaaa
      121 gaccaacggt cagccaatga acgataagag aaatgggcat tcttggttta ggcaacaaga
      181 acgtttagaa aacaaagtgc atagtctgag agaagagatc aagcaacaag aaaaacaggt
      241 agaaaaactt gaaagacaag aagagctaaa ggaaatgggc tataacaagt acggcggcct
      301 ggatatgaca atcgaaaata ttccaagaat caaagaagaa atcgaacgct ttgaaaaagg
      361 tgaatcgact ttttcagccg ctacgatccg aaaataccaa cggaaattgg aaacattaga
      421 acagctgaaa gaaagatcag aaaaaggaaa agaaaatctt cttcctgaag tacaagcaat
      481 tattgacagc ggacgagtga cgcaatggaa aaaaaatcca accatttatt ttttgaaaga
      541 ctatcgaaaa gttgctttag aactgaatga aaacggggga tttgaggaat caaaaaaata
      601 ccaagccacg tcggaagagg aaaaagcagc tgttcgtgaa ttacttgaag aggctgcgcc
      661 aactgattct ttgaaggaga aagaaaacga tcatttctat cgagtagaat tcaacgaaaa
      721 tgatccagaa aaaggattga aaagttatgg tggggagatc gtaacatt
//
LOCUS       DAXLPY010000209          767 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.221, whole genome shotgun sequence.
ACCESSION   DAXLPY010000209 DAXLPY010000000
VERSION     DAXLPY010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.221"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            2..767
                     /locus_tag="ACF3UF_002866"
                     /pseudo
     CDS             2..767
                     /locus_tag="ACF3UF_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          329 a          114 c          174 g          150 t
ORIGIN      
        1 catggcagaa gaaaaagaac cactagacaa tagtcgtttg ggaaaatcca aaagaaaatt
       61 agtacgattg caaaatgaat taaacgaaca aattgaaaag atgtttgaac accagagaaa
      121 gaccaacggt caaccaatga acgataagag aaatgggcat tcttggttta ggcaacaaga
      181 gcgaatcgaa aataaagtgc atagtctgag agaagagatc aagcaacaag aaaaacaagt
      241 agaaaaactt gaaagacaag aagagataaa ggaaatgggc tataacaagt acggcggact
      301 ggatatgacg atcgagaata ttccaagaat caaagaagaa atcgaacgct ttgaaaaagg
      361 tgaatcgact ttttcagccg ctacgatccg aaaataccaa cggaaattgg aaacattaga
      421 acagctgaaa gaaagatcgg aaaaaggaaa agaaaacctt cttcctgaag tacaagcaat
      481 cattgacagc ggacgagtga cgcaatggaa aaaaatccga ccatttattt tctgaaaggc
      541 tatcgaaaag tcgctttaga actgaatgaa aacggggaat ttgaggaatc taaaaaatac
      601 caagccacgt cggaagagga aaaagcagct gttcgtgaat tacttgaaga ggctgtacca
      661 actgattttt tgaaggagaa agaaaacgat catttttatc gagtagaatt caacgaaaat
      721 gatccagaaa aaggattgaa aagttatggt ggggagatcg taacatt
//
LOCUS       DAXLPY010000210          767 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.222, whole genome shotgun sequence.
ACCESSION   DAXLPY010000210 DAXLPY010000000
VERSION     DAXLPY010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.222"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..765
                     /locus_tag="ACF3UF_002867"
     CDS             <1..765
                     /locus_tag="ACF3UF_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFD3672887.1"
                     /translation="YYYWVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMK
                     GYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTD
                     VTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILH
                     SDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIE
                     IFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          332 a           96 c          127 g          212 t
ORIGIN      
        1 tattattact gggtaaaaaa attagataag ccagataaat atagcaagat aaagcaagaa
       61 attacagcga ttgtaaaaga atcaagaaac tcttatggtt atcgtagagt cactttagcg
      121 ttaaagatga aaggatatac aatcaatcat aaaacagtta gaaaattaat gtcccaaatg
      181 ggacttacct gtcaaatccg aataaagcga tataaatctt ataaaggaac agtaggaaaa
      241 attgccaaga atgtgttaaa acgaaatttt tcagtagata cacccaataa aaaatgggtg
      301 acagacgtca ctgaattcaa gataaaagga agaaaaatct atctatctcc tatacttgat
      361 ttatttaacg gagaaataat tagttatagt atatcaacta gtccaacata taaactgatt
      421 gaagaaatgc ttcaacaagc aattaaaaaa aagggaactg agggttcact gattctacat
      481 tcagatcaag gatggcagta tcagatgcca caatatcaaa aaaaattaaa agagaataac
      541 attattcaaa gcatgtctag aaaaggaaat tgcttagata attctgtaat agaaaatttt
      601 tttggtgtgc ttaaatcaga gtttttttat cgagaaaaat tccgatcaat tgagatattt
      661 caaagtaaat taaatgagta tattaggtgg tataataaca aaaggataaa actaaagtta
      721 aatggactat ctccagtaga atatcggaaa cagtccatta aatagtt
//
LOCUS       DAXLPY010000211          728 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.223, whole genome shotgun sequence.
ACCESSION   DAXLPY010000211 DAXLPY010000000
VERSION     DAXLPY010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.223"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..330
                     /locus_tag="ACF3UF_002868"
     CDS             <1..330
                     /locus_tag="ACF3UF_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3672888.1"
                     /translation="DLGGEKEKDIAVKLPGVTKNTNSKQSSDSKASFNHPSTFFNNNK
                     RSSNLNYNNSNKKRELMNQEKNKEGNRNKNTMELPKTGEKYNGLPVYVGLFTAIASII
                     GLKKNKF"
BASE COUNT          288 a          100 c          119 g          221 t
ORIGIN      
        1 gatcttggtg gagaaaaaga gaaagacata gcagtcaaat tacccggagt aacgaaaaat
       61 acaaattcta aacaaagttc ggatagtaaa gctagcttta atcatccttc tacttttttt
      121 aacaacaaca aaagatcatc taatctaaat tataataata gcaataaaaa aagggaacta
      181 atgaatcaag aaaaaaataa agaaggcaat cgaaataaaa atactatgga gttaccgaaa
      241 actggagaaa aatataatgg tcttcctgtg tatgtagggt tattcacggc gattgcaagt
      301 attatagggc tgaaaaaaaa taaattttaa tgtgggaatt attattattt ctctaattct
      361 atttgagcaa tttaaaatat gaaaatcaat aaagagaaag ttttaagttg ttaagtaaat
      421 taaatttcga ttggaagcat agttgaataa gcctaacatg ttacgaaaga taaataacct
      481 acttttcatt tctagaagag aatgtcttga tgcttataaa cagatttagc tccctatcca
      541 cttcaagtct aattcttttg tatgcaaata aagtattttt aggagagtgt tctcattaga
      601 gaacactctt tttttgtttt gaaaactact tactatacgg gtagtttcaa agtaagcgcc
      661 ccatagaaca gtaccttact aacaaatgca cctcaagata tacttgagct atcaagaagt
      721 ctggaggt
//
LOCUS       DAXLPY010000212          705 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.224, whole genome shotgun sequence.
ACCESSION   DAXLPY010000212 DAXLPY010000000
VERSION     DAXLPY010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.224"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..89
                     /locus_tag="ACF3UF_002869"
     CDS             <1..89
                     /locus_tag="ACF3UF_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFD3672889.1"
                     /translation="AKVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(352..>705)
                     /locus_tag="ACF3UF_002870"
     CDS             complement(352..>705)
                     /locus_tag="ACF3UF_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HFD3672890.1"
                     /translation="RATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSS
                     LETPSISPKETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQ
                     PPTPPIPKTPKLPGI"
BASE COUNT          200 a          106 c          127 g          272 t
ORIGIN      
        1 acgccaaagt aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata
       61 gttatctatt atttaacggg aggaaataat tctatgagtc gcttttgtaa atttggaaag
      121 ttacacgtta ctaaagggaa tgtagataaa ttattaggta tagggcacct ctaataacta
      181 ccaattaatt cacctcaaaa tgaaattaga aaaaaacagc gaaattttta aatctatttc
      241 ttatcgatac aaattcctcg taggcgctcg ggaccccaac atgaggaaat gtttttataa
      301 aaaaagagta gttaccgttt tttggtaact actcttttcc ttttttaagg tttaaatacc
      361 tggaagttta ggtgttttgg gtattggtgg tgtaggtggc tgcaagcttt ccaatttttg
      421 ttgaattgct ttaaattcag gtgtctcttg gtgtttattt agaaccattt tttgctctat
      481 tcgttctaaa gtcggttgaa tttctttccc tgatacttta cgattcaatt ctttttctaa
      541 ggtttctttt ggactaatag aaggtgtttc caaacttgaa tagagtttta ctccttctct
      601 gttatatagc cttatatcgc taaataagcc cgttttatga agggtttcta aattggtcgg
      661 taagtttttg acaacaatat catgcgcttg ttttggtgtt gccct
//
LOCUS       DAXLPY010000213          698 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.225, whole genome shotgun sequence.
ACCESSION   DAXLPY010000213 DAXLPY010000000
VERSION     DAXLPY010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.225"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..627
                     /locus_tag="ACF3UF_002871"
     CDS             <1..627
                     /locus_tag="ACF3UF_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HFD3672891.1"
                     /translation="LVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQI
                     MNRFRTSHSENQKKYRRLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLS
                     YNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISN
                     AFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT          221 a          155 c          127 g          195 t
ORIGIN      
        1 ctagtgatgg acatgaatgc cagctattgt cagttgctta aaacagtctt tccaaatgcg
       61 gagatcgtaa ctgaccgctt tcatattgtc caacacatca atcgcagctt caatcaatta
      121 cgtgtccaga tcatgaatcg ttttcgaacc tcacactctg aaaatcagaa gaagtaccgt
      181 cggctcaagc gatattggaa actcttactc aaagattcca cgacatggga gccactcaaa
      241 cggcattatc atcgactgtt taaacgacca attagtcaaa cagaaatcgt tgatgagctg
      301 ttaagctaca acgaagaatt gcgaactgcg tatcattttt gtcaattatt acgctattat
      361 ttcgttaaac gaggtacgga aggctttcaa gaaaccctta aaacaatttc atctacgtta
      421 cctcagtcgt ttaaaaagaa attcacgatc ttccattgct accaatcggg tatttcaaat
      481 gcctttaagg tgtcccactc aaacggcgtc actgaggggc tgaataacaa gatcaagctg
      541 attaaacgaa ttgcgtttgg ttatcgcaac ttttataact ttcgggcacg gatctattta
      601 caacaaggtc tgatctttga aaactaaaaa aatatgcggc gcacagaacg cgccgcatat
      661 cggactaagt tttattcaaa tttgtcttca ccaacacg
//
LOCUS       DAXLPY010000214          696 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.226, whole genome shotgun sequence.
ACCESSION   DAXLPY010000214 DAXLPY010000000
VERSION     DAXLPY010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.226"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(53..628)
                     /locus_tag="ACF3UF_002872"
     CDS             complement(53..628)
                     /locus_tag="ACF3UF_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFD3672892.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DAXLPY010000215          666 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.227, whole genome shotgun sequence.
ACCESSION   DAXLPY010000215 DAXLPY010000000
VERSION     DAXLPY010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.227"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>666
                     /locus_tag="ACF3UF_002873"
     CDS             <1..>666
                     /locus_tag="ACF3UF_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFD3672893.1"
                     /translation="MYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAIYMDATYI
                     PLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERGVKNVLLF
                     ITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMVYQASSKK
                     AALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIESFNKQIK
                     KYS"
BASE COUNT          197 a          147 c          146 g          176 t
ORIGIN      
        1 aaatgtatgg gcatcactac acgccccaaa ccatgtccaa tatgactaaa tcatttacgg
       61 aagaagtcac ttcatttaag gaacgtgagc ttcatgaccg ttatgccgct atttatatgg
      121 acgcaaccta tatcccttta aagcggaaaa ccgtcgccaa ggaagccatt catatcgcag
      181 ttggcattcg cccggacggt tcaaaggaag tgttgagcta tgcgattgca ccaactgaat
      241 ctatcacgat ttgggaagag attttaatag acctccagga acgtggcgtg aaaaacgtcc
      301 tccttttcat cacggatggc ttaaagggga tggcaggggc cgtgcagcgg ttctacccca
      361 aagcccgttt tcaacattgc tgtgtgcacg tttcccgtaa tatcagtcac aaagtgcgtg
      421 tcgatgatcg taaggaagtc tgtgatgatt ttaaaatggt gtatcaagcg tcatctaaaa
      481 aggcggcatt ggaagcacgt ggtgcttttg cggaaaaatg gaaaaccagt tatccaaaaa
      541 tggtggaatc gatcctttcg aacgattacc tgctcacttt ctatgatttt ccattagcca
      601 tacgcaagac tatttactct acgaacttga ttgaatcctt taataagcaa atcaagaaat
      661 acagcc
//
LOCUS       DAXLPY010000216          666 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.228, whole genome shotgun sequence.
ACCESSION   DAXLPY010000216 DAXLPY010000000
VERSION     DAXLPY010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.228"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>666
                     /locus_tag="ACF3UF_002874"
     CDS             <1..>666
                     /locus_tag="ACF3UF_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HFD3672894.1"
                     /translation="MYGYHYTPQTMSKMTKVLTEEVNAFKVRTLNDKYVAIFMDATYI
                     PLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRGVHDVLLF
                     ITDGLKGMKDTIHQIYPKAKYQHCCVHVSRNIAHKVRVKDRKEICDDFKAVYQASSKE
                     EANTFLGSMIEKWQKTYPKVTQSLIKNQDLLTFYEFPPGIRRSIYSTNLIESFNKQIK
                     KYS"
BASE COUNT          227 a          123 c          125 g          191 t
ORIGIN      
        1 aaatgtatgg gtatcactac acgccccaaa ccatgtccaa aatgactaaa gtgctgactg
       61 aagaagtaaa tgcatttaaa gttagaactc taaatgataa gtatgtcgct attttcatgg
      121 atgctactta tattccttta aaacggcaaa ccgtctccaa agaagcaatc tatattgcca
      181 ttggtatacg agaagacggc actaaagaag tactaagtta tgcgattgct ccgactgaat
      241 cgacctacgt ttggaatgag ttgttacagg acatttactc cagaggggtt catgatgtct
      301 tactgtttat caccgatggc ttaaaaggca tgaaagatac gattcaccag atttatccta
      361 aagctaaata ccaacattgc tgtgttcacg tttcccgtaa tattgctcat aaagtacgtg
      421 tcaaagatcg aaaagaaatc tgtgatgatt ttaaggctgt ttatcaagct agctcaaagg
      481 aagaggcaaa taccttttta gggagtatga ttgagaagtg gcagaaaact tatcctaaag
      541 tgacgcagtc actgataaaa aatcaagatt tattgacttt ttatgagttt ccgcctggta
      601 tccgccgaag catttactca actaatttaa tcgaatcttt caataaacaa atcaagaaat
      661 acagcc
//
LOCUS       DAXLPY010000217          643 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.229, whole genome shotgun sequence.
ACCESSION   DAXLPY010000217 DAXLPY010000000
VERSION     DAXLPY010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.229"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..283
                     /locus_tag="ACF3UF_002875"
     CDS             <1..283
                     /locus_tag="ACF3UF_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3672895.1"
                     /translation="LIQDDLHHTHRLWLMNKINLYFGHSYVFAFYDYRTNITEVDLVI
                     SNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKEVVKSAFCPEY"
BASE COUNT          219 a           89 c          119 g          216 t
ORIGIN      
        1 tttaatacaa gatgatttac accatacgca tcggttatgg ttaatgaata aaattaatct
       61 gtattttggg cattcttatg tttttgcttt ttatgattac aggacaaata taactgaagt
      121 agatttggtt atttctaatt actacatcga cactggaaaa acgccattac tgttaatgaa
      181 aaatatacct accgaaagaa actggcgttt gttcgagaaa acgatttatc aattgaaaaa
      241 agaaaaagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca aacggaaaaa
      301 tagtttttca tattttgccg tttttgagct aataccgagg gacagctgat tgaacaccat
      361 ttattgagag attgtgaaaa aactgtcctg catcaagtaa taagaacagc caagtaaaaa
      421 cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca agagaacacc
      481 gtttattcgg aaaaagggac tgtgacacta catgtcacag tccctttttg attgaattat
      541 ctcatttgtt ttctaatttt ttctttattt gagaaaatag ttgaactgga taaaaagtac
      601 tggacgtgtc aaaattattt tggatcaaat tagatctatt att
//
LOCUS       DAXLPY010000218          639 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.230, whole genome shotgun sequence.
ACCESSION   DAXLPY010000218 DAXLPY010000000
VERSION     DAXLPY010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.230"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            477..623
                     /locus_tag="ACF3UF_002876"
                     /pseudo
     CDS             477..623
                     /locus_tag="ACF3UF_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
BASE COUNT          214 a           90 c           98 g          237 t
ORIGIN      
        1 cctttaatac aaagatttta tttttaaata aaaaatactc tttttttacg attattgaaa
       61 aaaaaagata aaacttgatt aattgaagta ttgcttaaat ttggaagcta tgagggaaga
      121 ataaaagagt taggacggga ttatctacta tttttctttg ttttaaatat ttgttatctt
      181 tgaacataaa agagaaatgt gtcgactgca gtgttgtgtc cctcatcacg aataaacggt
      241 gttcaattag ctgatcttgt attaacttaa aaaatggtaa agtacgagtt gctattcccc
      301 attttcaatt ttctaacgct caggacaaaa tactgttttc acaacctcat tggaataaaa
      361 gcatatatat tgtttcaaga acgaaatctt gttatctttt taaagggcat ctgtccaaaa
      421 tctaatttta ggaggtacgt tttggtattt attcgtacaa ataaaagaga attatcttta
      481 ttcatgtaac gcatccaatt gattttttca tgtacgctcc tggaacgatt ttactgacga
      541 ttgcttattt aactgcgaat cgctcattag cttttatcat agctatccat attttgaata
      601 acgttcttgg ctttgtatta tagatacaga tgacaaaaa
//
LOCUS       DAXLPY010000219          633 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.231, whole genome shotgun sequence.
ACCESSION   DAXLPY010000219 DAXLPY010000000
VERSION     DAXLPY010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.231"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            125..322
                     /locus_tag="ACF3UF_002877"
     CDS             125..322
                     /locus_tag="ACF3UF_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFD3672896.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            324..>633
                     /locus_tag="ACF3UF_002878"
     CDS             324..>633
                     /locus_tag="ACF3UF_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD3672897.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
BASE COUNT          244 a           61 c          115 g          213 t
ORIGIN      
        1 cttaaaagtg attaaattct tattcaggaa ttattttgct acgtttcaag aaggaattgt
       61 tttttgaaat ttaatgaatg ttagaataat agtctaaaaa cattaattta ggggtgatta
      121 gattatgaaa catttaaaaa ttttgtctat taaagagaca caacttatct atgggggtac
      181 cactcatagt ggaaaatatt atggaaatgg agtgtattgc actaaaaata aatgtacggt
      241 cgattgggcc aaggcaacta cttgtattgc aggaatgtct ataggtggtt ttttaggtgg
      301 agcaattcca gggaagtgct aaaatgaaaa aaaatgctaa gcaaattgtt catgaattat
      361 ataatgatat atctataagt aaagatccta aatattctga tattcttgag gttttacaaa
      421 aggtatattt aaaattagaa aaacaaaaat atgaattaga tcccggtcct ttaataaata
      481 gattggtgaa ttatctatat tttactgctt atactaataa aataagattc actgaatatc
      541 aagaggaatt aataagaaat ttgagtgaaa ttggaagaac tgctggaata aatggtttat
      601 atcgagcaga ttatggagat aaatctcaat ttt
//
LOCUS       DAXLPY010000220          575 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.232, whole genome shotgun sequence.
ACCESSION   DAXLPY010000220 DAXLPY010000000
VERSION     DAXLPY010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.232"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            22..>575
                     /locus_tag="ACF3UF_002879"
     CDS             22..>575
                     /locus_tag="ACF3UF_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFD3672898.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRT"
BASE COUNT          205 a           95 c          115 g          160 t
ORIGIN      
        1 aagatagcag gaggaatgac gatgaatcat tttaaaggaa agcaatttca gcaggatgtg
       61 attattgtag ccgtgggcta ctatcttcgt tataacctta gctatcgtga agttcaagaa
      121 atcttatatg atcgtggcat taacgtttct catacgacga tttatcgttg ggtgcaagaa
      181 tatggcaaac tactctatca aatttggaaa aagaaaaata aaaaatcctt ttattcatgg
      241 aaaatggatg aaacgtacat caaaattaaa ggaaaatggc attatttgta tcgagccatc
      301 gatgcagatg gtttaacctt ggatatttgg ttacgtaaaa aacgggacac acaagcagcc
      361 tatgcttttc ttaagcggtt agtgaagcag tttgatgaac cgaaggttgt agtcacagat
      421 aaagccccct ctattacaag tgcctttaag aaactaaaag aatacggctt ttatcaaggg
      481 acagaacatc gtaccattaa atacctgaat aatttgattg aacaagacca tcgtccagta
      541 aagagacgca ataaattcta tcgaagttta cgcac
//
LOCUS       DAXLPY010000221          570 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.233, whole genome shotgun sequence.
ACCESSION   DAXLPY010000221 DAXLPY010000000
VERSION     DAXLPY010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.233"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..>570)
                     /locus_tag="ACF3UF_002880"
     rRNA            complement(<1..>570)
                     /locus_tag="ACF3UF_002880"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          112 a          183 c          123 g          152 t
ORIGIN      
        1 ggcgtggact accagggtat ctaatcctgt ttgctcccca cgctttcgag cctcagcgtc
       61 agttacagac cagagagccg ccttcgccac tggtgttcct ccatatatct acgcatttca
      121 ccgctacaca tggaattcca ctctcctctt ctgcactcaa gtctcccagt ttccaatgac
      181 cctccccggt tgagccgggg gctttcacat cagacttaag aaaccgcctg cgctcgcttt
      241 acgcccaata aatccggaca acgcttgcca cctacgtatt accgcggctg ctggcacgta
      301 gttagccgtg gctttctggt tagataccgt caagggatga acagttactc tcatccttgt
      361 tcttctctaa caacagagtt ttacgatccg aaaaccttct tcactcacgc ggcgttgctc
      421 ggtcagactt tcgtccattg ccgaagattc cctactgctg cctcccgtag gagtttgggc
      481 cgtgtctcag tcccaatgtg gccgatcacc ctctcaggtc ggctatgcat cgtggccttg
      541 gtgagccgtt acctcaccaa ctagctaatg
//
LOCUS       DAXLPY010000222          548 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.234, whole genome shotgun sequence.
ACCESSION   DAXLPY010000222 DAXLPY010000000
VERSION     DAXLPY010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.234"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..399
                     /locus_tag="ACF3UF_002881"
     CDS             <1..399
                     /locus_tag="ACF3UF_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3672899.1"
                     /translation="FDKLPKKVSSDVKDELKSIFKASELELTRERKEHFLEKYGCDSK
                     LSAACDILENGFEDAIQILSFPENIRRRIRTTNVLERLNEEIRRRERVIRIFPNINSI
                     TRIIGTLLMEKDTEWLASPRKYLEFNSNNI"
BASE COUNT          171 a           99 c          118 g          160 t
ORIGIN      
        1 tttgataagc tgccaaagaa agtttcttct gatgtaaaag acgagttgaa gagtatcttt
       61 aaagcctctg aacttgaatt gacacgtgaa agaaaagagc acttcttgga aaaatatggt
      121 tgtgattcaa aattaagtgc tgcttgcgac attttagaaa acggctttga agatgctatt
      181 caaattttgt cttttcctga aaatatccgc cgaaggattc gtacaaccaa tgtgttggaa
      241 cggttgaacg aagagattcg ccggagagaa cgagtgattc ggatttttcc aaatatcaat
      301 tccatcactc ggataattgg aacacttttg atggaaaaag acactgagtg gctggcttct
      361 ccacgaaaat atttagaatt taattcgaat aacatttagc accatgaacc tgtgcgagtc
      421 tcttctttct gaggagagac atcaagagtc gctgcgctac tgctcctgac ctctctcctc
      481 agaaagaaag gcatggcagt taggttcaca acgcaaaaca ttgtgctttt gatgaggttg
      541 aactttta
//
LOCUS       DAXLPY010000223          543 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.235, whole genome shotgun sequence.
ACCESSION   DAXLPY010000223 DAXLPY010000000
VERSION     DAXLPY010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.235"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            391..474
                     /locus_tag="ACF3UF_002882"
                     /pseudo
     CDS             391..474
                     /locus_tag="ACF3UF_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502600.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MLS leader peptide"
BASE COUNT          170 a           71 c          106 g          196 t
ORIGIN      
        1 aaaaagcttt aactacaagc tttttagaca tctaatcttt tctgaagtac atccgcaact
       61 gtccatactc tgatgtttta tatcttttct aaaagttcgc tagatagggg tcccgagcgc
      121 ctacgaggaa tttgtatcga taagaaatag atttaaaaat ttcgctgtta ttttgtacat
      181 ttaacttgac ggtgacatct ctctattgtg agttattagt ggtacagttt tcaaccgttt
      241 taattataaa aaagtggtgc atttttaaat tggcacaaac aggtaacggt tattgcaggt
      301 gtatttctta tctatgggtt taacatggat tttatcatta aaatcatgag tattgtccga
      361 gagtgattgg tcttgcgtat ggttaaccct aaagttatgg aaataagact tagaagcaaa
      421 cttaagagtg tgttgatagt gcattatctt aaaattttgt ataataggaa ttgaagttaa
      481 attagatgct aaaaatttgt aattaagaag gagggattcg tcatgttggt attccaaatg
      541 cgt
//
LOCUS       DAXLPY010000224          536 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.236, whole genome shotgun sequence.
ACCESSION   DAXLPY010000224 DAXLPY010000000
VERSION     DAXLPY010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.236"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>536
                     /locus_tag="ACF3UF_002883"
     CDS             <1..>536
                     /locus_tag="ACF3UF_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFD3672900.1"
                     /translation="YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNK
                     LSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKV
                     DKWFPSSQICSECGHKDG"
BASE COUNT          210 a           71 c           96 g          159 t
ORIGIN      
        1 tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa ttccacaatt
       61 ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa aattgataat
      121 aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa attgtctagg
      181 cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa ttatcaaaaa
      241 caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga agacttaaac
      361 acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt ttcttggtca
      421 aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat catcaaagta
      481 gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga tggcaa
//
LOCUS       DAXLPY010000225          531 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.237, whole genome shotgun sequence.
ACCESSION   DAXLPY010000225 DAXLPY010000000
VERSION     DAXLPY010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.237"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>531
                     /locus_tag="ACF3UF_002884"
     rRNA            <1..>531
                     /locus_tag="ACF3UF_002884"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          155 a          107 c          150 g          119 t
ORIGIN      
        1 gtatgtagtc gtagacccga aaccatgtga tctacccatg tccaggttga aggtgcggta
       61 aaacgcactg gaggaccgaa cccacgtacg ttgaaaagtg cggggatgag gtgtgggtag
      121 cggagaaatt ccaaacgaac ttggagatag ctggttctct ccgaaatagc tttagggcta
      181 gcctcggaat tgagaatgat ggaggtagag cactgtttgg actaggggcc catctcgggt
      241 taccgaattc agataaactc cgaatgccat tcattcatat ccgggagtca gactgtgagt
      301 gataagatcc atagtcgaaa gggaaacagc ccagaccacc agctaaggtc ccaaaatata
      361 tgttaagtgg aaaaggatgt ggggttgcac agacaactag gatgttggct tagaagcagc
      421 caccatttaa agagtgcgta atagctcact agtcgagtga ccctgcgccg aaaatgtacc
      481 ggggctaaac atattaccga agctgtggag tacaccttta ggtgtattgg t
//
LOCUS       DAXLPY010000226          505 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.238, whole genome shotgun sequence.
ACCESSION   DAXLPY010000226 DAXLPY010000000
VERSION     DAXLPY010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.238"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..475
                     /locus_tag="ACF3UF_002885"
     CDS             <1..475
                     /locus_tag="ACF3UF_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672901.1"
                     /translation="KKKQQAITPSENKQLEVHQVQEIKTSSNVERQSRGRTKKVGAPI
                     RKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELLRKALDEYIKQNLTQEDKQ
                     DLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDTEDSLRKGWGMNNKVR"
BASE COUNT          215 a           73 c           98 g          119 t
ORIGIN      
        1 aaagaaaaag cagcaagcaa ttacaccatc tgaaaataag caattagaag tgcaccaagt
       61 tcaagaaata aaaacttcct ccaatgttga aagacagagt agaggaagaa caaaaaaagt
      121 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
      181 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      241 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      301 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      361 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      421 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      481 aaagaagaac taagtaacta ccttt
//
LOCUS       DAXLPY010000227          503 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.239, whole genome shotgun sequence.
ACCESSION   DAXLPY010000227 DAXLPY010000000
VERSION     DAXLPY010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.239"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            22..492
                     /locus_tag="ACF3UF_002886"
     CDS             22..492
                     /locus_tag="ACF3UF_002886"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFD3672902.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKITAAIESVL"
BASE COUNT          186 a           93 c           76 g          148 t
ORIGIN      
        1 aaatagaaag gagaaaactt tatgtctatt tataattttg aaactacttt agaagacggc
       61 actgtctatt cattgaaaaa atatgcaggc aaaccgataa tcattgttaa cactgcaaca
      121 aaatgcggtc tagcacctca atttaaacaa ttagaagaac tttaccaagc ttatcagaca
      181 caaggtctgg ttatcttagg ctttccttcc aatcaattta aacaagagct agattcagcg
      241 actgaagcag cagaagcttg taaaaccact tatggcgtta ccttccctat gcatcaattg
      301 attgacgtaa atggagaaaa tacagatcct ctttttactt atcttaaaaa tgaagctcct
      361 ggtactgtca ctaaagcaat aaaatggaat tttactaaat ttttgattga tagaaatggc
      421 aaagtaatcg aacgatttgc accacaaact tctccattga aaataaccgc tgcaattgaa
      481 tccgttcttt aacttaataa aaa
//
LOCUS       DAXLPY010000228          499 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.240, whole genome shotgun sequence.
ACCESSION   DAXLPY010000228 DAXLPY010000000
VERSION     DAXLPY010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.240"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>499
                     /locus_tag="ACF3UF_002887"
     rRNA            <1..>499
                     /locus_tag="ACF3UF_002887"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          162 a           99 c          141 g           97 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaa
//
LOCUS       DAXLPY010000229          498 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.241, whole genome shotgun sequence.
ACCESSION   DAXLPY010000229 DAXLPY010000000
VERSION     DAXLPY010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.241"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
BASE COUNT          197 a           51 c           75 g          175 t
ORIGIN      
        1 ttttttgttg atttaccaac atgtttagac attttcctct aggaaaaaat taactagcac
       61 cacgggtttt tgtactatta attgtgattt ttaaatgatt gaaaaataga gaggaggaag
      121 caatacgtag aaaaaatatt ttaaattggt gtaagtacaa atatgttatt tacagtattt
      181 tagtttctcg tattaagtgt tactactatg gtgaattctt tagagaatta ataaatagtc
      241 ttctttgata gattgttaaa gggaacttaa caaagtaata agatgcataa tcaaatgcac
      301 aaaaaacaaa aaaagaagtt tcttcgaata gaaattctga aataacatcc tttcgcctaa
      361 tagtgaataa tttaaataaa gagaaactgg ctacactatc aaagcaagtg attctgttta
      421 gctaattact aataattaaa gtattaaaat agtatgttta atcaaataga acaagattgg
      481 ataatagttt atattttt
//
LOCUS       DAXLPY010000230          468 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.242, whole genome shotgun sequence.
ACCESSION   DAXLPY010000230 DAXLPY010000000
VERSION     DAXLPY010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.242"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>468
                     /locus_tag="ACF3UF_002888"
     CDS             <1..>468
                     /locus_tag="ACF3UF_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HFD3672903.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DAXLPY010000231          464 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.243, whole genome shotgun sequence.
ACCESSION   DAXLPY010000231 DAXLPY010000000
VERSION     DAXLPY010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.243"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            73..234
                     /locus_tag="ACF3UF_002889"
     CDS             73..234
                     /locus_tag="ACF3UF_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFD3672904.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..>464
                     /locus_tag="ACF3UF_002890"
     CDS             253..>464
                     /locus_tag="ACF3UF_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3672905.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQF"
BASE COUNT          179 a           48 c           80 g          157 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaa
//
LOCUS       DAXLPY010000232          460 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.244, whole genome shotgun sequence.
ACCESSION   DAXLPY010000232 DAXLPY010000000
VERSION     DAXLPY010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.244"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(20..91)
                     /locus_tag="ACF3UF_002891"
     tRNA            complement(20..91)
                     /locus_tag="ACF3UF_002891"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="ACF3UF_002892"
     tRNA            complement(113..200)
                     /locus_tag="ACF3UF_002892"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="ACF3UF_002893"
     tRNA            complement(225..298)
                     /locus_tag="ACF3UF_002893"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="ACF3UF_002894"
     tRNA            complement(312..382)
                     /locus_tag="ACF3UF_002894"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="ACF3UF_002895"
     tRNA            complement(384..459)
                     /locus_tag="ACF3UF_002895"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DAXLPY010000233          459 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.245, whole genome shotgun sequence.
ACCESSION   DAXLPY010000233 DAXLPY010000000
VERSION     DAXLPY010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.245"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            149..390
                     /locus_tag="ACF3UF_002896"
                     /pseudo
     CDS             149..390
                     /locus_tag="ACF3UF_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
BASE COUNT          190 a           54 c           91 g          124 t
ORIGIN      
        1 tctttctcaa aataaacata aaagcccttt aaagagggct tttatatatt aatcacaaat
       61 cacttatcac aaatcactta tcacaaatca caagtgattt gtgattgttg atgataaaat
      121 aagaataaga agaaatagaa agaagtgagt gattgtggga aatttaggcg cacaaaaaga
      181 aaaacgaaat gatacaccaa tcagtgcaaa aaaagatata atgggagata agacggttcg
      241 tgttcgtgct gacttgcacc atatcataaa aatcgaaaca gcaaagaatg gcggaaacgt
      301 aaaagaagtt atggaaataa gacttagaag caaacttaag agtgtgttga tagtgcagta
      361 tcttaaaatt ttgtgtataa taggaattga agttaaatta gatgctaaaa atttgtaatt
      421 aagaaggagg gattcgtcat gttggtattc caaatgcgt
//
LOCUS       DAXLPY010000234          440 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.246, whole genome shotgun sequence.
ACCESSION   DAXLPY010000234 DAXLPY010000000
VERSION     DAXLPY010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.246"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            11..>440
                     /locus_tag="ACF3UF_002897"
     CDS             11..>440
                     /locus_tag="ACF3UF_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3672906.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          168 a           57 c           88 g          127 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag
//
LOCUS       DAXLPY010000235          421 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.247, whole genome shotgun sequence.
ACCESSION   DAXLPY010000235 DAXLPY010000000
VERSION     DAXLPY010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.247"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            17..>421
                     /locus_tag="ACF3UF_002898"
     CDS             17..>421
                     /locus_tag="ACF3UF_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFD3672907.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMS"
BASE COUNT          155 a           78 c           69 g          119 t
ORIGIN      
        1 aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc tagtcactaa
       61 aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca cactcctacg
      121 gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt ttaattcagg
      181 taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg aattaacatt
      241 ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag cctacaaaag
      301 aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg ttacgatgtc
      361 tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac aaaccatgtc
      421 c
//
LOCUS       DAXLPY010000236          417 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.248, whole genome shotgun sequence.
ACCESSION   DAXLPY010000236 DAXLPY010000000
VERSION     DAXLPY010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.248"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..159
                     /locus_tag="ACF3UF_002899"
     CDS             <1..159
                     /locus_tag="ACF3UF_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFD3672908.1"
                     /translation="SQLLEVNLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQ
                     VLNKEKVA"
     gene            161..>417
                     /locus_tag="ACF3UF_002900"
     CDS             161..>417
                     /locus_tag="ACF3UF_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFD3672909.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEK"
BASE COUNT          155 a           59 c           77 g          126 t
ORIGIN      
        1 tctcaattat tggaagtcaa tttattaaac caattaaagc ttgcaaaacg tgtaaatctt
       61 tttgattatt ctttagaaga attacaagcc gttcatgagt attggcggtc aatgaatcgt
      121 tactcaaaac aagttttgaa taaagagaaa gtggcttaat atggcaaata tagtcaattt
      181 tactgacaaa caatttgaga atcgcttaaa tgataattta gaagaattga ttcaaggaaa
      241 aaaagcggtt gaatcgccaa ccgctttttt acttggtggg caaccagggt cagggaaaac
      301 cagtttgcga tcagcaattt ttgaagaaac acaagggaat gttattgtca ttgataatga
      361 tacctttaaa caacagcacc ctaattttga tgaactagtg aaactttatg aaaaaga
//
LOCUS       DAXLPY010000237          415 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.249, whole genome shotgun sequence.
ACCESSION   DAXLPY010000237 DAXLPY010000000
VERSION     DAXLPY010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.249"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..339)
                     /locus_tag="ACF3UF_002901"
     CDS             complement(<1..339)
                     /locus_tag="ACF3UF_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672910.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DAXLPY010000238          400 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.250, whole genome shotgun sequence.
ACCESSION   DAXLPY010000238 DAXLPY010000000
VERSION     DAXLPY010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.250"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            108..383
                     /locus_tag="ACF3UF_002902"
     CDS             108..383
                     /locus_tag="ACF3UF_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672911.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
BASE COUNT          172 a           60 c           54 g          114 t
ORIGIN      
        1 ataaataacc actatttgat ttatatatat ttcagtatcc ttcttgtttt catataacca
       61 aaggcgctat gatttccata tgaaaaaaat aaagtcaggt gaaaaaaatg aaacttgagg
      121 ataaaaaagt cattttgaag aaaatcaaac gactaccaga ccaaatagat ggctatacga
      181 tctgttcttt caaaaaagac aggagtataa aagcttatac gcaaaacaca gaaaaaggaa
      241 taatctattt cctacatgaa gaaggttacg atacccaaac ctttatgttt actgaaaaaa
      301 aagaatttca taaacagatg aaaaaactga ttgaaaaaga atttccaaga agtcataaac
      361 tctatgtgaa tcagcaattt taacttctaa ctgttcttta
//
LOCUS       DAXLPY010000239          389 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.251, whole genome shotgun sequence.
ACCESSION   DAXLPY010000239 DAXLPY010000000
VERSION     DAXLPY010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.251"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..374
                     /locus_tag="ACF3UF_002903"
     CDS             <1..374
                     /locus_tag="ACF3UF_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3672912.1"
                     /translation="CDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDL
                     LTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKF
                     LNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          146 a           71 c           59 g          113 t
ORIGIN      
        1 tctgtgatga ctttaaggct gtttatcaag ctaactcaaa agaagaagcg aataccttct
       61 tatccggcat gattgagaaa tggaagaaaa actatcctaa agtgacgcag tcactcatag
      121 aaaaccaaga cttattaact ttttatgatt ttccacctag cattcgtaga accatttact
      181 caaccaatct aatcgagtct ttcaataagc aaattaaaag atacagccgt agaaaagagc
      241 agtttcaaaa tgaagaatca ctagaacgct ttctagtcag catttttgat acatacaatc
      301 aaaaatttct aaacagaagc cataaaggtt ttcaacaggt aaccgataca ttagtttcaa
      361 tgtttactga gtaactaatt attttgcag
//
LOCUS       DAXLPY010000240          387 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.252, whole genome shotgun sequence.
ACCESSION   DAXLPY010000240 DAXLPY010000000
VERSION     DAXLPY010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.252"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..382
                     /locus_tag="ACF3UF_002904"
     CDS             <1..382
                     /locus_tag="ACF3UF_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3672913.1"
                     /translation="KRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWL
                     KTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNR
                     NRIHSSIHYLTPQEFEELAKEKMA"
BASE COUNT          154 a           73 c           68 g           92 t
ORIGIN      
        1 aaaacgaatg actgtggatt gtgtcattca aacattgaat aaagcaaaaa tacattatca
       61 cattccagaa ggaatgattc tacacactga cttgggcagc caatacacag caagagaagt
      121 ggaacaatgg cttaaaacca acaaaataag gcattcttat agtagaaaag gaacacctta
      181 tgataatgct ggaatcgaat ctttccatgc ctcattgaaa aaagaagaag tctacacgac
      241 tagctactca gattttgaag aagcaaatcg agcgctattt agctacattg aaggatttta
      301 taaccgaaat cgaatccata gctcgattca ctatctaacc ccacaggaat ttgaagaatt
      361 agcaaaagaa aaaatggctt aaccgtc
//
LOCUS       DAXLPY010000241          381 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.253, whole genome shotgun sequence.
ACCESSION   DAXLPY010000241 DAXLPY010000000
VERSION     DAXLPY010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.253"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..>381)
                     /locus_tag="ACF3UF_002905"
     rRNA            complement(<1..>381)
                     /locus_tag="ACF3UF_002905"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           85 a          110 c           94 g           92 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc a
//
LOCUS       DAXLPY010000242          379 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.254, whole genome shotgun sequence.
ACCESSION   DAXLPY010000242 DAXLPY010000000
VERSION     DAXLPY010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.254"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..274
                     /locus_tag="ACF3UF_002906"
     CDS             <1..274
                     /locus_tag="ACF3UF_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HFD3672914.1"
                     /translation="LIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERINE
                     LIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
BASE COUNT          130 a           66 c           78 g          105 t
ORIGIN      
        1 actcatcaag ctggctaata agggtcaaga ttatgaacat ctagcagatg agattgatga
       61 gctgagagac aagcgacagc tccttttagt agaagatgcc tccctcagtg gcgagaacga
      121 gcgaatcaat gagctgattg aatttatccg caagaacaaa ttccgtacct tagagtacga
      181 tgataagctt gtaaggaaga taatccagag cgttacagtc tatgaagaac acttcgtcat
      241 atccttcaaa tctggcatcg aaatggaaat atgaaaacca gaagtaaata gcccatgatt
      301 ctacagtaga gtcgtgggtt ttcttttgct tgctgattat aataatattt taataactat
      361 tgttattata aaccaaatg
//
LOCUS       DAXLPY010000243          362 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.255, whole genome shotgun sequence.
ACCESSION   DAXLPY010000243 DAXLPY010000000
VERSION     DAXLPY010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.255"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..321)
                     /locus_tag="ACF3UF_002907"
     CDS             complement(<1..321)
                     /locus_tag="ACF3UF_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672915.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLES"
BASE COUNT          116 a           72 c           47 g          127 t
ORIGIN      
        1 agattccaat tgtgaaacta aattttcttt catatcaaca ggtatctccc aataaccatc
       61 gatacattga aataactcct cgtcatactc ttcaaaaatt ggatagattc ttaaaaaatc
      121 atcaaatgat aagccttggt cctcatagta atctttgact aatccatttt caattgcctg
      181 ttgggtcggt aaacccgttt cagtaataat tcctctctct accatcgaac gataaaaagt
      241 gcatttatct agcgattgct gggtcgtttc aagataatac tttaatcctt cttcaactaa
      301 aggtgggtaa ataatttcca ttttggttcc ctcctaaaag ttatatatta aactattttg
      361 aa
//
LOCUS       DAXLPY010000244          362 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.256, whole genome shotgun sequence.
ACCESSION   DAXLPY010000244 DAXLPY010000000
VERSION     DAXLPY010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.256"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..>362)
                     /locus_tag="ACF3UF_002908"
     rRNA            complement(<1..>362)
                     /locus_tag="ACF3UF_002908"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           81 a          114 c           68 g           99 t
ORIGIN      
        1 tctcactaga agcttttctc ggcagtgtga catcaggaac ttcggtacta ttatttccct
       61 ccccatcaca gcttgtcctt aagaaaagaa gcatttgact cctcttcaga cttactgctt
      121 ggacagacat ttccgatcgt ctgcattcct tagcctcctg cgtccctcca ttgctcaaac
      181 aaaaacaacg ggtacaggaa tatcaacctg ttatccatcg cctacgcctg tcggcctcgg
      241 cttaggtccc gactaaccct gggcggacga gccttcccca ggaaacctta gtcattcggt
      301 ggacaggatt ctcacctgtc tttcgctact cataccggca ttctcacttc taagcgctcc
      361 ag
//
LOCUS       DAXLPY010000245          351 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.257, whole genome shotgun sequence.
ACCESSION   DAXLPY010000245 DAXLPY010000000
VERSION     DAXLPY010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.257"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            76..>351
                     /locus_tag="ACF3UF_002909"
     CDS             76..>351
                     /locus_tag="ACF3UF_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672916.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDV"
BASE COUNT          141 a           59 c           63 g           88 t
ORIGIN      
        1 agaaaaataa aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa
       61 ggagtgtaac cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa
      121 tcatattatc ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata
      181 caaactattt ataatgtagt caataagttc aagcaaggca agactgctct tgattattgg
      241 caccagtata aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat
      301 gaagtagatt acattaaaga gaaagtcact cttggttgga cgcctgacgt c
//
LOCUS       DAXLPY010000246          349 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.258, whole genome shotgun sequence.
ACCESSION   DAXLPY010000246 DAXLPY010000000
VERSION     DAXLPY010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.258"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(44..>349)
                     /locus_tag="ACF3UF_002910"
     CDS             complement(44..>349)
                     /locus_tag="ACF3UF_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3672917.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT           98 a           86 c           64 g          101 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggt
//
LOCUS       DAXLPY010000247          347 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.259, whole genome shotgun sequence.
ACCESSION   DAXLPY010000247 DAXLPY010000000
VERSION     DAXLPY010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.259"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>347
                     /locus_tag="ACF3UF_002911"
     CDS             <1..>347
                     /locus_tag="ACF3UF_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3672918.1"
                     /translation="GRKALDIETALNQWFSRFPKNFFKSITFDCGKEFSNWKAISNQH
                     DIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRKVNQTFISSVSNQRNHIPRKS
                     LNYRTPIEIFLSYV"
BASE COUNT          116 a           67 c           58 g          106 t
ORIGIN      
        1 ggccgtaagg cattagatat tgaaactgcc cttaatcaat ggttttctcg cttccctaaa
       61 aacttcttta aatctattac gtttgactgt ggaaaagaat tttctaactg gaaagccatt
      121 agtaaccaac atgatattga tatatatttt gcggaccctg gaacaccttc tcaacgccca
      181 ttaaacgaga attctaacgg gattctgcgt cgtaatggac tgccgaaatc aatggatttt
      241 agaaaagtga atcagacatt tatttccagt gtcagcaatc aacgtaatca tattccaaga
      301 aaatcattga attacagaac accaatcgaa atatttttga gctatgt
//
LOCUS       DAXLPY010000248          342 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.260, whole genome shotgun sequence.
ACCESSION   DAXLPY010000248 DAXLPY010000000
VERSION     DAXLPY010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.260"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
BASE COUNT          146 a           48 c           31 g          117 t
ORIGIN      
        1 aaacaaaaat aaataaagtc ggatttttct gataattcaa cgcaaaaaaa cgaacaattt
       61 ttcaataaat cagtcttcta aaatagataa cctaaaaaaa acgaacaaac aaataaaatg
      121 actgtccttc attcactaaa catattttta ttttttatat tgttaaaaat tcacaattat
      181 tttttaatag aattatctgt tttccaaatt ttataacata aaaaaccttt tttaacggca
      241 tttatatgct ttttcagaaa ttaactgatg atttcaaaaa gaaaacatgt cataatattt
      301 cccatattgt gcaaaaaaat acaaggtgga ggctctacta tg
//
LOCUS       DAXLPY010000249          340 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.261, whole genome shotgun sequence.
ACCESSION   DAXLPY010000249 DAXLPY010000000
VERSION     DAXLPY010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.261"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            43..165
                     /locus_tag="ACF3UF_002912"
     CDS             43..165
                     /locus_tag="ACF3UF_002912"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672919.1"
                     /translation="MHKPFPDPIQKAIDELGIKNKKRFILVIHYMTCKVRKLVG"
BASE COUNT          123 a           45 c           64 g          108 t
ORIGIN      
        1 aatctatatt ttgatataca aattacagct tcagatacta agttgcataa accttttccg
       61 gaccccatac aaaaggcaat tgatgaattg ggcataaaaa ataagaaacg atttatattg
      121 gtgattcatt atatgacatg caaagtgcga aagcttgtgg gatagcattt ggtttagcta
      181 aatggggagc caaaaatata gaaaattttc aaagtgtaga tataattatt gattctcctc
      241 aagaaatact tgatttgtta gaaaaataga caaagagcgt gagataagga tagggtctca
      301 cgctctttgt ttttcgccat ttaaagattg aaatttttgc
//
LOCUS       DAXLPY010000250          336 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.262, whole genome shotgun sequence.
ACCESSION   DAXLPY010000250 DAXLPY010000000
VERSION     DAXLPY010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.262"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(44..220)
                     /locus_tag="ACF3UF_002913"
     CDS             complement(44..220)
                     /locus_tag="ACF3UF_002913"
                     /inference="COORDINATES: protein motif:HMM:NF021542.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFD3672920.1"
                     /translation="MKEFIEKYKYPLIFACVGLLLGLLILTLGLFKIVIITILTVCGF
                     YLGIYLETIGFFDK"
BASE COUNT          116 a           46 c           37 g          137 t
ORIGIN      
        1 ataaaaattt attttttacc gtaaaaacgg ttattaacta gttttatttg tcaaaaaatc
       61 caatagtttc taaatagata cctaaataaa aaccacatac agtaagtatt gttattatca
      121 ctattttaaa aagtcctaac gtgagaatta ataatcctaa tagtagtcct acacatgcaa
      181 aaatgagcgg atatttatat ttctctatga attctttcat tgttttctcc tataaaactt
      241 ttgatttggt ttctttattt ctttcatgat aatcattgaa ttttatttca gttagtattg
      301 tttgttctgc accaaataag gcattcaaat tagtgt
//
LOCUS       DAXLPY010000251          315 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.263, whole genome shotgun sequence.
ACCESSION   DAXLPY010000251 DAXLPY010000000
VERSION     DAXLPY010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.263"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(68..>315)
                     /locus_tag="ACF3UF_002914"
     CDS             complement(68..>315)
                     /locus_tag="ACF3UF_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="chromosome partitioning protein ParA"
                     /protein_id="HFD3672921.1"
                     /translation="VPYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTWS
                     KNGITEHKGYDKKVLSMYKNVFFEMLERIIQLENEKE"
BASE COUNT           88 a           54 c           42 g          131 t
ORIGIN      
        1 tcttatttta tcatcaacaa tcacaaatca caagtgattt gtgattaatc acttgtgatt
       61 tgtgattcta ttctttttcg ttttctaatt gaataattcg ctcaagcatt tcaaaaaata
      121 cgttcttata catggataaa acttttttgt catagccttt atgctctgta atgccgtttt
      181 tagaccaggt acttacttta ttacttcgct tgataatatt ttggaaaacc aagttatctt
      241 ctttatgttg cttatacagt tcttccaggt ttgattttat cgttgcgctg tccgtatcaa
      301 ctaaataagg aacaa
//
LOCUS       DAXLPY010000252          314 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.264, whole genome shotgun sequence.
ACCESSION   DAXLPY010000252 DAXLPY010000000
VERSION     DAXLPY010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.264"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..197
                     /locus_tag="ACF3UF_002915"
     CDS             <1..197
                     /locus_tag="ACF3UF_002915"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3672922.1"
                     /translation="SVRGLAKEYGLSEATIYKWKNLYLPDQSTGLTGKEVAELRKENA
                     RLNEELEILKKAAAIFSRKT"
BASE COUNT          108 a           46 c           64 g           96 t
ORIGIN      
        1 gttctgttcg agggttagcg aaagaatatg gcttatctga agcaacgatt tacaaatgga
       61 agaatttata tttacctgat cagtccacag gactgactgg aaaagaagta gctgaactga
      121 gaaaagaaaa tgctcgttta aatgaggaac ttgaaatctt aaaaaaagcc gcagccatat
      181 tctctcggaa aacctaaatt cgcttgttca atttattgaa aaatggtgta aggattacac
      241 tgtttctttg ttgtgtcggt tattagaaat ccctagaagt gtctattatt tttataagaa
      301 taaaccgttg acag
//
LOCUS       DAXLPY010000253          307 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.265, whole genome shotgun sequence.
ACCESSION   DAXLPY010000253 DAXLPY010000000
VERSION     DAXLPY010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.265"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACF3UF_002916"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACF3UF_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFD3672923.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           96 a           45 c           50 g          116 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttat
//
LOCUS       DAXLPY010000254          294 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.266, whole genome shotgun sequence.
ACCESSION   DAXLPY010000254 DAXLPY010000000
VERSION     DAXLPY010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.266"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            22..>294
                     /locus_tag="ACF3UF_002917"
     CDS             22..>294
                     /locus_tag="ACF3UF_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HFD3672924.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYT"
BASE COUNT           98 a           49 c           67 g           80 t
ORIGIN      
        1 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
       61 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      121 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      181 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      241 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacc
//
LOCUS       DAXLPY010000255          290 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.267, whole genome shotgun sequence.
ACCESSION   DAXLPY010000255 DAXLPY010000000
VERSION     DAXLPY010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.267"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
BASE COUNT          104 a           24 c           46 g          116 t
ORIGIN      
        1 ttgatacagt tcgtagagtg ttaaaacaag accgggattg ttgttttatc aaggtcaata
       61 ctggaagaag tagacgttta gcaaaacgat ataatagttt gattaattag ttgtaacagt
      121 agagcagatt aattttcttt tattaggatt tgatctgctc tttattatgt ataggaatta
      181 acatattcga aaaaatatta caaaattgta atgctattat ttataattaa ttattttaca
      241 atgctaaaat tgatgataat attttattgt atctgttaat aaaagttttt
//
LOCUS       DAXLPY010000256          265 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.268, whole genome shotgun sequence.
ACCESSION   DAXLPY010000256 DAXLPY010000000
VERSION     DAXLPY010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.268"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>265
                     /locus_tag="ACF3UF_002918"
     CDS             <1..>265
                     /locus_tag="ACF3UF_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672925.1"
                     /translation="KLTILELKRTRFLCHDCGRTFSAKTDLVDEHHQLTKELKQAILM
                     ELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL"
BASE COUNT           83 a           56 c           58 g           68 t
ORIGIN      
        1 aaagttaact attttagaat taaaacgtac ccgttttctc tgccatgatt gtggaaggac
       61 cttttctgcg aaaacggact tagttgatga acatcatcaa ctaacaaagg aactgaagca
      121 ggcgattctc atggaactgt acgaaaatca atcacgtaaa ctaatcgcta agaagtactt
      181 cgtctcggat gggacggtga cacggatctt gcgtgaagca acgaagcatt accagccacg
      241 tatgaacttc cttccgacgg tgttg
//
LOCUS       DAXLPY010000257          259 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.269, whole genome shotgun sequence.
ACCESSION   DAXLPY010000257 DAXLPY010000000
VERSION     DAXLPY010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.269"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
BASE COUNT          104 a           42 c           27 g           86 t
ORIGIN      
        1 ctctactaca ccatatctat tgacaatcaa ccaaataaaa tacagtattt cacgatatag
       61 tgtgataaat aacaaaatag aagcaataaa gcttcttgtg ttaaaacaat tataaaagaa
      121 ctaaataatt agcccttcta tctataaaaa agtcaatagc gtcactagga tttcctaata
      181 acgctattga ttttcttttc ctctgaaatt aaatcagaaa gatttttcaa taatgataac
      241 tgttttgatt aacagcttt
//
LOCUS       DAXLPY010000258          258 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.270, whole genome shotgun sequence.
ACCESSION   DAXLPY010000258 DAXLPY010000000
VERSION     DAXLPY010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.270"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(170..>258)
                     /locus_tag="ACF3UF_002919"
     CDS             complement(170..>258)
                     /locus_tag="ACF3UF_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFD3672926.1"
                     /translation="AKVNDLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT           77 a           52 c           43 g           86 t
ORIGIN      
        1 gggtcccgag cgcttagtgg gaatttgtac cccttatcga tacaaattcc tcgtaggcgc
       61 tagggacctc tttagcttct tggaagctgt cagtagtata tctaataatt tatctccatt
      121 ccctttagta acgtgtaact ttccaaattt aaaaaagcga ctcatagaat tatttcctcc
      181 cgttaaataa tagataacta ttaaaaatag acaatacttg ctcataagta acggtactta
      241 aatcgtttac tttggcgt
//
LOCUS       DAXLPY010000259          257 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.271, whole genome shotgun sequence.
ACCESSION   DAXLPY010000259 DAXLPY010000000
VERSION     DAXLPY010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.271"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            163..>257
                     /gene="rrf"
                     /locus_tag="ACF3UF_002920"
     rRNA            163..>257
                     /gene="rrf"
                     /locus_tag="ACF3UF_002920"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT           89 a           44 c           64 g           60 t
ORIGIN      
        1 taggtcagga gtggaagtac agtgatgtat ggagcggact gatactaatc gatcgaggac
       61 ttaaccaata ggttaaaaga aaagaactcg gaaaaaaact tatgtgactt caaatccagt
      121 tttgagtgaa caaaatttac tcaataaaag ataacaccac agtgtggtgg cgatagcgag
      181 aaggatacac ctgtaaccat gccgaacaca gaagttaagc ttcttagcgc cgattgtagt
      241 gaggggttgc cccttgt
//
LOCUS       DAXLPY010000260          255 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.272, whole genome shotgun sequence.
ACCESSION   DAXLPY010000260 DAXLPY010000000
VERSION     DAXLPY010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.272"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..>255)
                     /locus_tag="ACF3UF_002921"
     CDS             complement(<1..>255)
                     /locus_tag="ACF3UF_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFD3672927.1"
                     /translation="AEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELL
                     KKANTIIVATDSDREGENIAWSIIHKANAFSKDKTFKRLW"
BASE COUNT           67 a           51 c           38 g           99 t
ORIGIN      
        1 atccatagtc ttttaaatgt tttatctttt gaaaaggcat ttgctttatg gataatcgac
       61 caggcgatat tttcaccttc tctgtcgcta tctgttgcaa caataattgt atttgccttt
      121 ttgagaagtt ctgcaacaat tttaaactgc tttcccttat cttttgcaac ttcaaaatcg
      181 tatcgatcag gaaaaatcgg caaagattca agtttccaat tttgccactt ttcgtcataa
      241 tgacctggtt ctgct
//
LOCUS       DAXLPY010000261          253 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.273, whole genome shotgun sequence.
ACCESSION   DAXLPY010000261 DAXLPY010000000
VERSION     DAXLPY010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.273"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>253
                     /locus_tag="ACF3UF_002922"
     CDS             <1..>253
                     /locus_tag="ACF3UF_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /protein_id="HFD3672928.1"
                     /translation="VEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVN
                     SVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKN"
BASE COUNT           83 a           54 c           44 g           72 t
ORIGIN      
        1 tgttgaagaa ggattctaca agcgtacctt ggatattcac cgaacactag ggttgctctt
       61 gcacactcaa gtctcgattc agcaattgct taagctgcca gcggaatgct ttcatcctaa
      121 accaaaagta aacagtgtct taataaaact tacccgccat accacagatg ttccagataa
      181 atattggaag ctatatacgt actttgtttc aaaatgggtc aatcgagaat atcgtcaact
      241 gtttactaaa aat
//
LOCUS       DAXLPY010000262          241 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.274, whole genome shotgun sequence.
ACCESSION   DAXLPY010000262 DAXLPY010000000
VERSION     DAXLPY010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.274"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..220)
                     /locus_tag="ACF3UF_002923"
     CDS             complement(<1..220)
                     /locus_tag="ACF3UF_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3672929.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DAXLPY010000263          236 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.275, whole genome shotgun sequence.
ACCESSION   DAXLPY010000263 DAXLPY010000000
VERSION     DAXLPY010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.275"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..>236)
                     /locus_tag="ACF3UF_002924"
     CDS             complement(<1..>236)
                     /locus_tag="ACF3UF_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672930.1"
                     /translation="VVEKENTRKPYTEVENGVSYIVPKGKRRQATLDAMKTNYVHELE
                     RFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEP"
BASE COUNT           57 a           57 c           30 g           92 t
ORIGIN      
        1 ggctctttta ccacttttgt taaggtgtta cgcaaatcac ttttccgcgt caataaattt
       61 cgtttctcca taccaatcat tcgatccttt tcataagaaa aacgttctaa ctcatgtaca
      121 taattggtct tcattgcgtc taatgttgct tgtcttctct tacctttcgg tacgatataa
      181 ctcacaccat tttcaacctc cgtgtaaggt ttacgcgtat tttctttttc aacaac
//
LOCUS       DAXLPY010000264          232 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.276, whole genome shotgun sequence.
ACCESSION   DAXLPY010000264 DAXLPY010000000
VERSION     DAXLPY010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.276"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
BASE COUNT           79 a           35 c           45 g           73 t
ORIGIN      
        1 gagaaaaagc atggaatgcg ctgcatcagg tatcgaggct tagaaaaaaa tcaggtgcat
       61 acgatgcttg tttttgccga aatgagtctg aaaaaattgg tcacttagca gtgggagcat
      121 atgtcttcat attttttatt atacaaaaat agacaaaagt atcagtctac actcttagta
      181 aagaggaaac tgatactttt gtctacagta tgatatttct tacatctact tt
//
LOCUS       DAXLPY010000265          229 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.277, whole genome shotgun sequence.
ACCESSION   DAXLPY010000265 DAXLPY010000000
VERSION     DAXLPY010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.277"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..185
                     /locus_tag="ACF3UF_002925"
     CDS             <1..185
                     /locus_tag="ACF3UF_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3672931.1"
                     /translation="YTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQ
                     RILDNELGCANASEAV"
BASE COUNT           61 a           51 c           57 g           60 t
ORIGIN      
        1 aatacacatt tgaaacctta caacaattgg atttggagtt atttgactat gtcaattggt
       61 ggaaccacct tcggttgcac ggtacacttg gctacgagac accggttggt taccgtaacc
      121 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
      181 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggagg
//
LOCUS       DAXLPY010000266          225 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.278, whole genome shotgun sequence.
ACCESSION   DAXLPY010000266 DAXLPY010000000
VERSION     DAXLPY010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.278"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(<1..175)
                     /locus_tag="ACF3UF_002926"
     rRNA            complement(<1..175)
                     /locus_tag="ACF3UF_002926"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           50 a           60 c           49 g           66 t
ORIGIN      
        1 cctgtttcca agtgttatcc ccttctgatg ggcaggttac ccacgtgtta ctcacccgtt
       61 cgccactcct ctttttccgg tggagcaagc tccggtggaa aaagaagcgt tcgacttgca
      121 tgtattaggc acgccgccag cgttcgtcct gagccaggat caaactctca taaaaagttc
      181 gaacaatctt gcgattgtta agctcaattt gtttgctagc atatt
//
LOCUS       DAXLPY010000267          212 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.279, whole genome shotgun sequence.
ACCESSION   DAXLPY010000267 DAXLPY010000000
VERSION     DAXLPY010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.279"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>212
                     /locus_tag="ACF3UF_002927"
     CDS             <1..>212
                     /locus_tag="ACF3UF_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3672932.1"
                     /translation="IAKNCQVSLTTVIRTLKEFKSYLPKQSKRILPRVLMVDEFRSHA
                     SIEDKMSFICADGETGQLIDVLPTRK"
BASE COUNT           66 a           38 c           44 g           64 t
ORIGIN      
        1 attgcgaaaa attgtcaggt atctttgacc accgttattc gtacgttgaa agagtttaaa
       61 agctacttac caaagcaatc taagaggatt ctccccagag tattgatggt tgatgaattt
      121 cgttcgcacg cttccataga agataaaatg agctttattt gcgcagatgg cgaaacagga
      181 caattaattg atgtcttgcc tacgcgtaaa tt
//
LOCUS       DAXLPY010000268          204 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.281, whole genome shotgun sequence.
ACCESSION   DAXLPY010000268 DAXLPY010000000
VERSION     DAXLPY010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.281"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>204
                     /locus_tag="ACF3UF_002928"
     CDS             <1..>204
                     /locus_tag="ACF3UF_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3672933.1"
                     /translation="LYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPD
                     NYPDFNSEFGHLEGDTIVGIHHK"
BASE COUNT           71 a           39 c           37 g           57 t
ORIGIN      
        1 cactttatcg tttattttct aaaggaatat ttgatattga cacactaccg atgaaaggta
       61 aaagaaaacc caatggccat caggaaaaac ggggaaaaca acagtatcag cgctcaatcc
      121 atgatcgacc tgataattat cctgatttca attctgagtt tggtcacctt gaaggtgata
      181 cgatcgttgg cattcatcat aaaa
//
LOCUS       DAXLPY010000269          202 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.denovo.282, whole genome shotgun sequence.
ACCESSION   DAXLPY010000269 DAXLPY010000000
VERSION     DAXLPY010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.denovo.282"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..>202
                     /locus_tag="ACF3UF_002929"
     CDS             <1..>202
                     /locus_tag="ACF3UF_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /protein_id="HFD3672934.1"
                     /translation="GNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLTKTNVKELLEGK
                     ETLVKGIKNKEKKPYNAVVKIG"
BASE COUNT           89 a           25 c           38 g           50 t
ORIGIN      
        1 gtggcaacaa tattgtatta aaaaaatcgt tttatggttg ttcaaattat cctgaatgta
       61 agtttacttt agctgaacat tttagaaaga aaaaactaac caaaacgaat gtaaaagaat
      121 tactggaggg aaaagaaacc ctggtaaaag gaatcaaaaa caaagagaaa aagccctaca
      181 atgccgttgt aaaaattggg ga
//
LOCUS       DAXLPY010000270         8983 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.086, whole genome shotgun sequence.
ACCESSION   DAXLPY010000270 DAXLPY010000000
VERSION     DAXLPY010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.086"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            110..679
                     /locus_tag="ACF3UF_002930"
     CDS             110..679
                     /locus_tag="ACF3UF_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFD3672935.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            746..1483
                     /locus_tag="ACF3UF_002931"
     CDS             746..1483
                     /locus_tag="ACF3UF_002931"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3672936.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            1714..2982
                     /locus_tag="ACF3UF_002932"
     CDS             1714..2982
                     /locus_tag="ACF3UF_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFD3672937.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            3469..3933
                     /locus_tag="ACF3UF_002933"
     CDS             3469..3933
                     /locus_tag="ACF3UF_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3672938.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            3917..4546
                     /locus_tag="ACF3UF_002934"
     CDS             3917..4546
                     /locus_tag="ACF3UF_002934"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFD3672939.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            4900..6378
                     /gene="msr(C)"
                     /locus_tag="ACF3UF_002935"
     CDS             4900..6378
                     /gene="msr(C)"
                     /locus_tag="ACF3UF_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFD3672940.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            6425..6871
                     /locus_tag="ACF3UF_002936"
     CDS             6425..6871
                     /locus_tag="ACF3UF_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFD3672941.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(7070..7585)
                     /locus_tag="ACF3UF_002937"
     CDS             complement(7070..7585)
                     /locus_tag="ACF3UF_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3672942.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            7702..8904
                     /locus_tag="ACF3UF_002938"
     CDS             7702..8904
                     /locus_tag="ACF3UF_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3672943.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         2900 a         1565 c         1872 g         2646 t
ORIGIN      
        1 aaaaaagcat accactaagt atagttaaaa ggaatagtta agtatgtttt ataagtatta
       61 gacatcataa gccgtccgtt ataaagtaag gataaaagga gggagcaaaa tgacaagcct
      121 catcgaaaaa caaatcgtca ataaagagat tcgagtaacg gatccgctct ttgaagtgat
      181 ccatcagatc caagcggaaa acgaagagcc tttagcagcg ctgaatactg ggtaccatga
      241 accagcagat atccgcaaac ggctagaaaa tatcattagt gacaaagtag atgatacggt
      301 gactgttctg ctgccttttt atacagattt cggcaaacat attagtatag ggaaaaatgt
      361 ctttatcaat cgtcaagtga tgttcgttga cttaggtggc atctgtttag aagattcagt
      421 attgattggt cctcgtgtca acctcatcac ggtgaaccat ctaaccgatc caaaagaacg
      481 aagaggcttg tcagtaaagc caatccacat caagaaaaat gcttggatcg gagcaggagc
      541 aactattctg ccaggcgtaa cgattggcga gaatgccatt gttgcagcga atgcaactgt
      601 tacgaaagat gtcccagaca ataccatcgt tgcaggaatc cctgccaaaa tcgtcaaacc
      661 tgtcgaacgg attatttgaa cagtaagatg aaataagaga tagtgagtat aagcaagaga
      721 tttttcaaaa caggaggaga atagaatgaa tgatttatca gaaaaagtga ttgtcatcat
      781 gggcgcttca agcggaatcg gtgaagcaac aacgaagcta ttagcagaaa aaggggctaa
      841 actagttata gctgcacgcc gagaagatcg cctaaaagca ataaaagaat ctttaccaga
      901 agctgagcta tatattcaaa cagcagatgt aagagatttt gcacaagtcc aagcagttat
      961 cgatttagcg atggaaaagt tcggtcgaat cgatgtattg tacaataatg caggaatcat
     1021 gccaaccgct ccattagttg aaggtcaccg tgatgaatgg caaaatatgc ttgatatcaa
     1081 catcatgggt gtgttaaatg gaatttccgc cgtacttcca atcatggaaa aacaaaaatc
     1141 tgggcatatc atttcaactg attctgtggc gggacatgtt gtttatcctg attccgccgt
     1201 ttattgcgga acaaaatttg ctgtccgtgc aatcatggaa ggattacgtc aagagcaacg
     1261 gcaaaataac atcaaatcta cgatcatctc tccaggagct gttcaaactg aattatatca
     1321 aaccatcagc gacaaaaagg ctgctcttga acttcatgaa gcgcaaaaag aatggggatt
     1381 aacatctgaa gatatagctt ctgctgtagc atttgcgata gaaacgccag accggatgtc
     1441 tgtcagcaac atgattatcc gtccgacgac acaggaagta taatccataa cggataatat
     1501 ccagagagaa ttacttgtta aatagttatt caaacgacca tcaatttaag gcgtgaatgg
     1561 agaagaatat tcttcattta cgtcttttta tgcagaaaaa gcaaatttat taaaaagaaa
     1621 caaatgttat ttaaatatgg acattgactt gcttttactt ttttagttac actgttattt
     1681 aggaaaagtt tcataattca aaggagaaaa aagatgaaag caaagaattt attatttagc
     1741 gttattcttt taggaaatct agcagttgcc aacacaacag tgctagctga agaatcgaca
     1801 gaaactgtcg caactcagac atcgagttct tcagaaacag gaattgaaaa cgatacagaa
     1861 agtactttgc agtcagctac tgtctcagaa aatacaattt caaccgaaga accaacaact
     1921 gaaacaacag aacaaacaca aaccgaagac agtacatcag cagaagctca gaacaatcca
     1981 gagaatgcag aagaaatcac gaaccaattg acagatgggc aaacattgac acatacccat
     2041 caagcagatt tgtctgaatt cgaaaactat actggctatg ctttttatgc tcgctcatct
     2101 gctaattctc aacaagcgtt cattgatagt attgcctcaa ctgcacaaag tttggcaagt
     2161 gccaatgact tatatgcatc agtcatgatt gctcaagcca tcgttgaaag tggctggggg
     2221 aacagtactt tggcttctgc ccctaattac aatctatttg ggattaaagg aagctataat
     2281 ggccaatctg ttacgatgcc tacttcggaa tatgtgaatg ggcaatggat tacggtgaat
     2341 gccgctttta gaaaatatcc ttcgtacaaa gaatcattgc aagataacgt aacggtattg
     2401 aagacgactt cttttcagcc aggcgtttac tactattccg gtgcatggaa aagcaatacg
     2461 aactcttaca aagatgctac ggcttggcta acaggtcgtt atgccactgc gcctaattat
     2521 ggttctacat tgaacaatgt aatcgaaacc tataatctga cacagtatga tacagcacca
     2581 acttcaactt ctccgatgta tcgtctgtat aaccgtcata caggagaaca tttatataca
     2641 ttgaatgccg gagaaaaaaa ttatctgcca actgtaggct gggaatatga agggattgct
     2701 tggcaagcac caaacagcgg acaacctgtc taccgtttat acaatcctta cagtggagac
     2761 catcattaca caatggcaca atctgagatc aactctttaa caaaaatcgg ttggcgttat
     2821 gaaggtctaa gtttttattc tggtggttcc aagccaattt atcgactatt taatccaaat
     2881 gaaaaaactg gtacccatca ctataccttg agtgctaagg aaagagattg gctaacaccg
     2941 atgggctgga gatatgaagg aataggattt tatggttatt aaaaagaggt agtgaaaaag
     3001 ctgccctgca tcaagtagta agaacagcca aacaaaaaca gattttcatg ttttttgttt
     3061 ggttgaactt attaccgcag atgcaagttt ttgaacaccg tttactcaaa aaaggttgtg
     3121 acaacatctt gtcataactt ttttattact gtttaagcat actgatccaa tttctaatat
     3181 tcgacgggat tcttgcaaaa ggcgatttcg gaaatttttg gcggtgtaaa attatctact
     3241 gcagaagagc tatcttctat agtttgataa gaatcaataa tcttggtttt agcgttgtgc
     3301 tttctttatc attttttccg ttcattctac aaaaaatttc ttttctctat acttttctat
     3361 tgagagcgtt ttttttatta cacagctgat tctttgactt ttttcttttt ttattctatt
     3421 attgacaagt caatcgttga cgagtcaatt attagaaagg aggaaattat gtctttagaa
     3481 gagattagtc accttttata tcaaatcaaa ttagccgatc aaaaaatcgt ccagatcttt
     3541 gaagaaaata tcggtataag tcttactaga tacgagatca tgatgagact gaaagaagaa
     3601 aatccattgc tacaaagcag tttgcaagaa aagttgcaga ttgatcaagg agcagttact
     3661 cgtcatctga aggtattgga agcaaatggc tatgtttcgc gtcagagaaa tcctcagaac
     3721 aaccgggaag tgtatgtagc gctaacagaa aaagcccaga agaaaatcaa gcattgtgaa
     3781 atggaccata aagatacagg ttccgtgcta tccccggctt tcagcgatgt agaaatgaaa
     3841 caatttctaa cacttttaga taaattgaat acccaacttt gcaatataac aacagaaacg
     3901 aaagaggtta ataataatgg aacaaaaaaa tgatttttca acaattatga ctggtagaag
     3961 atccgttcgc gtatatgatg aaacatacaa aatcccacac gaagaaatgc tggaaatgat
     4021 caaagaagcg acgactgcac cttcttctgt caatatgaaa ccatggcgct ttgtggtcgc
     4081 tgaaagcgag gaagcaaaag aaatcttgcg tcctttgatc cgtttcaata cgagacaaaa
     4141 tgatacttct tctgcaatgg tcatgatttt tggcgatatg caatgttacg aatatggcga
     4201 agaaatctac aaccaagctt acgaatcagg gaagatgcca aaagaagtca gagatcaaca
     4261 attagctgcg atcattcctt attacaagag tttttcaaga gaagaaatga acgatgtagt
     4321 caaagtcgat tctagcttag cggctatgca attcatgtta gttgcgcgtg atcatggcta
     4381 tgaaacaaat ccaattggtg gattcgaagc agatcagttg gcagaggcat ttggtttgga
     4441 taaagaccgt tatgttccag ttattatttt atcaatagga aaagcggtag aagaaggtta
     4501 cgagtctgtt cgtttagcac cagaaaagat cactatgttc gaataaaagg ttttcagtta
     4561 ctattcagta gctattgctt tttttgaatc gtgtgtggta acctaataaa aaaggaggtc
     4621 ggaaaaatga ctgcatcgat gaaattacgt ttcgaacttt tgaataacaa ctaaataaat
     4681 tcaaaagaca tgtataaaca acaatttcat ggatggagta tgtccatttt ttcgaacgac
     4741 agtagaatag gtgaaagcta tgacagattt ggtgatttag tcatagttat ttcgttcaga
     4801 gtaggaaaag atgtgatgca gtttttttgc aaacagattt ttctgctctt ttttagtatc
     4861 gataattgtt gttttacatg aaataggagt gtaaaacata tggaaaattt agcagtaaat
     4921 ataacaaatc tacaagtcag ctttggcaac cagctagaac tatctattga ttctcttcgt
     4981 gtctatcagc aagatcgtat agggatcata ggagaaaatg gtgtcggtaa atcgactttg
     5041 ctcaaactaa tagccggtga actttttccc gatcatggga aaatccaaac agagatcacc
     5101 ttcaactacc tgcctcaatt aacctatctc gctgaagcaa aggacctaaa tttggaatta
     5161 gccagtcatt tccagttaag actggaagaa acttcagagc ggaaatggag cggaggggaa
     5221 gaacgaaaga tcgagttgat acgtcttctt tcttcttatg aacaagggat gcttctagac
     5281 gagccaacaa cccatctaga tagaaaaagt attgatcgac tgattgaaga gcttcgttat
     5341 tattatggta cgctggtttt tgttagtcat gatcgctatt ttctagatga gctagcatcg
     5401 aaaatctggg aagtaaaaga cggagaaatc cgagagtttt cggggaatta tagtgcctat
     5461 ctcactcaaa aggaattgga gaaaaagact cagctacgag aagcagagtc gatcatgaaa
     5521 gagaaaaaac gattggaaaa atcgatccaa gaaaagaaaa aacaagcgga aaagttggaa
     5581 aaagtgtcca gtaaaaagaa aaagcaacaa atcagactgg atcggttgtc ttcctctaaa
     5641 caaaaagaca gtgtacaaaa agccatccaa aagaatgcga aaacattaga gagaagactc
     5701 caaaaaatag gagaaacaac caagccgcag cagatgaaac aaatccgttt tccagtacca
     5761 aaatctcttg aactccacag ccgctatccc atcatgggac aaaatgtcca attggaaaga
     5821 agtgggagaa cattactggt aaatggtgat tttcagtttt ctttaggtaa aaaaatcgcg
     5881 attgtcggtg aaaatggttc aggtaagaca accttattag aacatatccg caaacaagga
     5941 gaaggaatcc ttctctctcc gaaagtaagc tttcaagtat atcagcaaaa gggttatcaa
     6001 atgacatctg aagaatccat cattcgtttt gtcatgagac aaacagagtt ttcagaatcg
     6061 cttgtccgta gtttgctgaa tcacttaggg tttgctcagg aaactttgac gaaaccgtta
     6121 tgtacattaa gtgggggaga agcgacccgt ctgacgattg ctttgctttt tactaagcca
     6181 agtaatgtgt tgctgttaga tgaaccgact aattttattg atatggcaac gatcgaagct
     6241 ttagagaagc taatgcaaat atatccggga acgattttgt ttacttctca tgattcttac
     6301 tttgtcgagc gtacggctga tgaagtttat gaaataaaag ggcagaaaat aaaaaaagta
     6361 cttacgagaa atttttaaat gtgctacgat gattttcgtg acaaatttaa aggagtggta
     6421 cagattgcct acaaataaaa aagaaggaat aatttttaca acaatgatgt gttttttgat
     6481 ggtcttgggg atgagcgcgt ataatttatg gctgcatcaa gatcttcatt tatcaagttt
     6541 gttgattggt ctagtgcctg gattcgtggt ggctttcatt ttggatgtct tcatcatcgg
     6601 tgtgctggcg aaaaaaattg cctttaaact accagtaaat ccagaaagca aggtccaaat
     6661 gatcttaact atttcatgct tgatggtttt aggaatggtg acatgtatgt ctttattcgg
     6721 tgtgatcatg gaacaaggaa tacctgatca attattctct gcttatatga atgcttggaa
     6781 aatgaatgtg attgccgctt taccgttgca gttgatcatc gttggcccgc tttcaagaag
     6841 tgtgctaaaa gcaattcaaa gtaatgaatg atggaacact gttatttgaa aaaaggcctt
     6901 ggcatgcttt ttgtcatagt ctcttgaatg cagttctaga aaaatagtga tccgaacgat
     6961 aggttttggc ctgtcgttcg gatcgctttt tcttttccaa ctgtattgct cttttattga
     7021 agataatttg ctcttcaata gatatttcta gaaaggttct gtttatccct tactcaaaaa
     7081 actgctgcat ttgttctctt acttgctgac accattggag ttcctgctga caaagcataa
     7141 ttctgcgctg gatcacaaca taacgtccaa attcttgttt cttgtctagc gagaggtcat
     7201 tcaatttttt ttgatttttt tgcatgattt tgttcagctg ttgttctcta gtgaatagca
     7261 gtccagtagc tgttgtttta tcgagcgtcg aaaaagcata gatttttgct agaaattcat
     7321 ctttttgcgt aggagcggga gtttcctctt tgatccattc ctctacaaga gcacgtcctt
     7381 catcagtcaa gtggtagatc tttttttgag agtgctcgtc tttgtccaaa acggtcacat
     7441 aaccctgctg gtctaacttg gcaagcgttg tatagatctg actgtgatgg gcttcccaaa
     7501 aaattgtgat cagctgcttc aattcatacc cagaacgtgg tttggataaa agcacgcata
     7561 ataatatata ggctaaagta ttcataaaaa tcctacctct cgtcttattt tctttattat
     7621 atcacagtaa agtttccacg ttttacatgt gcatattgac atgtaaaata aatcatgtat
     7681 gatgctaata gagagaaagg gatggaaata ttggagaatc aaatagatat acaagaacaa
     7741 acaaatgaag aaacaaaggg gaaaagttca gcgctagttg tagcagctac ctgtatgatc
     7801 gcttttatgg gagtgggtct agtagaccca atcttaaaaa cgattgctgc acagttaaac
     7861 gctacgccag ctgaaacgac cctgttattt actagttaca tgttagtcac tggtgtggtg
     7921 atgctattta caggtttctt atctagtcgg atcggtttga aaaaaacatt gatgacagga
     7981 ttgtttatca tcgttgtatt cgctggtctt ggcggattat ctgggaatat cggaatgctg
     8041 attgggttac gtgccggctg gggtgtcggg aatgctttat ttgtctctac tgctttagca
     8101 acgatcgtca gtattttagt tggtaacaca gaaaaagcaa tcatgatgta tgaagcagca
     8161 cttggctgcg gaatggctgt tggccctcta gtcggtgggg tcttgggcag tggttcatgg
     8221 cgttatccat tttttggggt agcatttttg atgttttgcg gttttatagc cctagcggta
     8281 cttttacctg aaactgagaa accaaagaga aaagtaggcc tttgggaagg tgtcaaagcg
     8341 ttaagcaatc ataaacttcg ttcagttgga ctaatcgcat tgttatataa tttcggattc
     8401 tttactttac ttgcgtatgc gccattttta ttgattggct attctgaatt agaagtcggt
     8461 tttgtatttt ttggctgggg tgtgcttctg gctattgctt cgattttcgt tgcaccggct
     8521 cttgagcgga agtttacgac ttatcggaca attttagcag catttgtctt attcattatt
     8581 tgtttgctgt tattaggagc tggaacttct atgccagtcc ttgtaccgat cagcattgtg
     8641 ttagcaggat ttttccaagg aattatcaat acactgttga cgacgattgc tatggaaata
     8701 ccaggtctgc aacgaaacgt tgcttcgtcc agctatagtt ttgtccgctt tttcggtgga
     8761 gctttagcac catttattgc aggtgtgatt ggtgaacata ttggtgaaag ctatgcgttt
     8821 tattttgcag gtgccattgt tcttatcagt gtatgttgta tcatttatca ccgtaattat
     8881 tttgctacaa atgaagaaga ataagaaatc agaggttgtg aaaaagctgt cctgcatcaa
     8941 gtcataagaa cagccaaaca aaaatagctt ctcatatttt tcg
//
LOCUS       DAXLPY010000271         7065 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.101, whole genome shotgun sequence.
ACCESSION   DAXLPY010000271 DAXLPY010000000
VERSION     DAXLPY010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.101"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            104..799
                     /gene="vanR-A"
                     /locus_tag="ACF3UF_002939"
     CDS             104..799
                     /gene="vanR-A"
                     /locus_tag="ACF3UF_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFD3672944.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            777..1931
                     /locus_tag="ACF3UF_002940"
     CDS             777..1931
                     /locus_tag="ACF3UF_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFD3672945.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2146..3114
                     /locus_tag="ACF3UF_002941"
     CDS             2146..3114
                     /locus_tag="ACF3UF_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFD3672946.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3107..4138
                     /gene="vanA"
                     /locus_tag="ACF3UF_002942"
     CDS             3107..4138
                     /gene="vanA"
                     /locus_tag="ACF3UF_002942"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFD3672947.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4144..4752
                     /locus_tag="ACF3UF_002943"
     CDS             4144..4752
                     /locus_tag="ACF3UF_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFD3672948.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            5202..6092
                     /locus_tag="ACF3UF_002944"
     CDS             5202..6092
                     /locus_tag="ACF3UF_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFD3672949.1"
                     /translation="MLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLENSGTSE
                     NTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDSNIYMS
                     KEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEHNSGL
                     SLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGLPHS
                     AIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEISGN
                     NIDGVIVTVFPGSTHTNSRR"
     gene            6245..6730
                     /gene="vanZ-A"
                     /locus_tag="ACF3UF_002945"
     CDS             6245..6730
                     /gene="vanZ-A"
                     /locus_tag="ACF3UF_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFD3672950.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT         2283 a         1238 c         1569 g         1975 t
ORIGIN      
        1 taaaatttgg tagtttataa aaagtatgaa ttattcaggt ataaattcgg ccctataatc
       61 tgataaatta ttaagggcaa acttatgtga aagggtgata actatgagcg ataaaatact
      121 tattgtggat gatgaacatg aaattgccga tttggttgaa ttatacttaa aaaacgagaa
      181 ttatacggtt ttcaaatact ataccgccaa agaagcattg gaatgtatag acaagtctga
      241 gattgacctt gccatattgg acatcatgct tcccggcaca agcggcctta ctatctgtca
      301 aaaaataagg gacaagcaca cctatccgat tatcatgctg accgggaaag atacagaggt
      361 agataaaatt acagggttaa caatcggcgc ggatgattat ataacgaagc cctttcgccc
      421 actggagtta attgctcggg taaaggccca gttgcgccga tacaaaaaat tcagtggagt
      481 aaaggagcag aacgaaaatg ttatcgtcca ctccggcctt gtcattaatg ttaacaccca
      541 tgagtgttat ctgaacgaga agcagttatc ccttactccc accgagtttt caatactgcg
      601 aatcctctgt gaaaacaagg ggaatgtggt tagctccgag ctgctatttc atgagatatg
      661 gggcgacgaa tatttcagca agagcaacaa caccatcacc gtgcatatcc ggcatttgcg
      721 cgaaaaaatg aacgacacca ttgataatcc gaaatatata aaaacggtat ggggggttgg
      781 ttataaaatt gaaaaataaa aaaaacgact attccaaact agaacgaaaa ctttacatgt
      841 atatcgttgc aattgttgtg gtagcaattg tattcgtgtt gtatattcgt tcaatgatcc
      901 gagggaaact tggggattgg atcttaagta ttttggaaaa caaatatgac ttaaatcacc
      961 tggacgcgat gaaattatat caatattcca tacggaacaa tatagatatc tttatttatg
     1021 tggcgattgt cattagtatt cttattctat gtcgcgtcat gctttcaaaa ttcgcaaaat
     1081 actttgacga gataaatacc ggcattgatg tacttattca gaacgaagat aaacaaattg
     1141 agctttctgc ggaaatggat gttatggaac aaaagctcaa cacattaaaa cggactctgg
     1201 aaaagcgaga gcaggatgca aagctggccg aacaaagaaa aaatgacgtt gttatgtact
     1261 tggcgcacga tattaaaacg ccccttacat ccattatcgg ttatttgagc ctgcttgacg
     1321 aggctccaga catgccggta gatcaaaagg caaagtatgt gcatatcacg ttggacaaag
     1381 cgtatcgact cgaacagcta atcgacgagt tttttgagat tacacggtat aacctacaaa
     1441 cgataacgct aacaaaaacg cacatagacc tatactatat gctggtgcag atgaccgatg
     1501 aattttatcc tcagctttcc gcacatggaa aacaggcggt tattcacgcc cccgaggatc
     1561 tgaccgtgtc cggcgaccct gataaactcg cgagagtctt taacaacatt ttgaaaaacg
     1621 ccgctgcata cagtgaggat aacagcatca ttgacattac cgcgggcctc tccggggatg
     1681 tggtgtcaat cgaattcaag aacactggaa gcatcccaaa agataagcta gctgccatat
     1741 ttgaaaagtt ctataggctg gacaatgctc gttcttccga tacgggtggc gcgggacttg
     1801 gattggcgat tgcaaaagaa attattgttc agcatggagg gcagatttac gcggaaagca
     1861 atgataacta tacgacgttt agggtagagc ttccagcgat gccagacttg gttgataaaa
     1921 ggaggtccta agagatgtat ataatttttt aggaaaatct caaggttatc tttacttttt
     1981 cttaggaaat taacaattta atattaagaa acggctcgtt cttacacggt agacttaata
     2041 ccgtaagaac gagccgtttt cgttcttcag agaaagattt gacaagatta ccattggcat
     2101 ccccgtttta tttggtgcct ttcacagaaa gggttggtct taattatgaa taacatcggc
     2161 attactgttt atggatgtga gcaggatgag gcagatgcat tccatgctct ttcgcctcgc
     2221 tttggcgtta tggcaacgat aattaacgcc aacgtgtcgg aatccaacgc caaatccgcg
     2281 cctttcaatc aatgtatcag tgtgggacat aaatcagaga tttccgcctc tattcttctt
     2341 gcgctgaaga gagccggtgt gaaatatatt tctacccgaa gcatcggctg caatcatata
     2401 gatacaactg ctgctaagag aatgggcatc actgtcgaca atgtggcgta ctcgccggat
     2461 agcgttgccg attatactat gatgctaatt cttatggcag tacgcaacgt aaaatcgatt
     2521 gtgcgctctg tggaaaaaca tgatttcagg ttggacagcg accgtggcaa ggtactcagc
     2581 gacatgacag ttggtgtggt gggaacgggc cagataggca aagcggttat tgagcggctg
     2641 cgaggatttg gatgtaaagt gttggcttat agtcgcagcc gaagtataga ggtaaactat
     2701 gtaccgtttg atgagttgct gcaaaatagc gatatcgtta cgcttcatgt gccgctcaat
     2761 acggatacgc actatattat cagccacgaa caaatacaga gaatgaagca aggagcattt
     2821 cttatcaata ctgggcgcgg tccacttgta gatacctatg agttggttaa agcattagaa
     2881 aacgggaaac tgggcggtgc cgcattggat gtattggaag gagaggaaga gtttttctac
     2941 tctgattgca cccaaaaacc aattgataat caatttttac ttaaacttca aagaatgcct
     3001 aacgtgataa tcacaccgca tacggcctat tataccgagc aagcgttgcg tgataccgtt
     3061 gaaaaaacca ttaaaaactg tttggatttt gaaaggagac aggagcatga atagaataaa
     3121 agttgcaata ctgtttgggg gttgctcaga ggagcatgac gtatcggtaa aatctgcaat
     3181 agagatagcc gctaacatta ataaagaaaa atacgagccg ttatacattg gaattacgaa
     3241 atctggtgta tggaaaatgt gcgaaaaacc ttgcgcggaa tgggaaaacg acaattgcta
     3301 ttcagctgta ctctcgccgg ataaaaaaat gcacggatta cttgttaaaa agaaccatga
     3361 atatgaaatc aaccatgttg atgtagcatt ttcagctttg catggcaagt caggtgaaga
     3421 tggatccata caaggtctgt ttgaattgtc cggtatccct tttgtaggct gcgatattca
     3481 aagctcagca atttgtatgg acaaatcgtt gacatacatc gttgcgaaaa atgctgggat
     3541 agctactccc gccttttggg ttattaataa agatgatagg ccggtggcag ctacgtttac
     3601 ctatcctgtt tttgttaagc cggcgcgttc aggctcatcc ttcggtgtga aaaaagtcaa
     3661 tagcgcggac gaattggact acgcaattga atcggcaaga caatatgaca gcaaaatctt
     3721 aattgagcag gctgtttcgg gctgtgaggt cggttgtgcg gtattgggaa acagtgccgc
     3781 gttagttgtt ggcgaggtgg accaaatcag gctgcagtac ggaatctttc gtattcatca
     3841 ggaagtcgag ccggaaaaag gctctgaaaa cgcagttata accgttcccg cagacctttc
     3901 agcagaggag cgaggacgga tacaggaaac ggcaaaaaaa atatataaag cgctcggctg
     3961 tagaggtcta gcccgtgtgg atatgttttt acaagataac ggccgcattg tactgaacga
     4021 agtcaatact ctgcccggtt tcacgtcata cagtcgttat ccccgtatga tggccgctgc
     4081 aggtattgca cttcccgaac tgattgaccg cttgatcgta ttagcgttaa aggggtgata
     4141 agcatggaaa taggatttac ttttttagat gaaatagtac acggtgttcg ttgggacgct
     4201 aaatatgcca cttgggataa tttcaccgga aaaccggttg acggttatga agtaaatcgc
     4261 attgtaggga catacgagtt ggctgaatcg cttttgaagg caaaagaact ggctgctacc
     4321 caagggtacg gattgcttct atgggacggt taccgtccta agcgtgctgt aaactgtttt
     4381 atgcaatggg ctgcacagcc ggaaaataac ctgacaaagg aaagttatta tcccaatatt
     4441 gaccgaactg agatgatttc aaaaggatac gtggcttcaa aatcaagcca tagccgcggc
     4501 agtgccattg atcttacgct ttatcgatta gacacgggtg agcttgtacc aatggggagc
     4561 cgatttgatt ttatggatga acgctctcat catgcggcaa atggaatatc atgcaatgaa
     4621 gcgcaaaatc gcagacgttt gcgctccatc atggaaaaca gtgggtttga agcatatagc
     4681 ctcgaatggt ggcactatgt attaagagac gaaccatacc ccaatagcta ttttgatttc
     4741 cccgttaaat aaacttttaa ccgttgcacg gacaaactat ataagctaac tctttcggca
     4801 ggaaacccga cgtatgtaac tggttcttag ggaatttata tatagtagat agtattgaag
     4861 atgtaaggca gagcgatatt gcggtcatta tctgcgtgcg ctgcggcaag atagcctgat
     4921 aataagactg atcgcataga ggggtggtat ttcacaccgc ccattgtcaa caggcagttc
     4981 agcctcgtta aattcagcat gggtatcact tatgaaaatt catctacatt ggtgataata
     5041 gtaaatccag tagggcgaaa taattgactg taatttacgg ggcaaaacgg cacaatctca
     5101 aacgagattg tgccgtttaa ggggaagatt ctagaaatat ttcatacttc caactatata
     5161 gttaaggagg agactgaaaa tgaagaagtt gttttttttt attgttattg ttattcttaa
     5221 tatacttagg ttatgactac gttaatgaag cactgttttc tcaggaaaaa gtcgaatttc
     5281 aaaattatga tcaaaatccc aaagaacatt tagaaaatag tgggacttct gaaaataccc
     5341 aagagaaaac aattacagaa gaacaggttt atcaaggaaa tctgctatta atcaatagta
     5401 aatatcctgt tcgccaagaa agtgtgaagt cagatatcgt gaatttatct aaacatgacg
     5461 aattaataaa tggatacggg ttgcttgata gtaatattta tatgtcaaaa gaaatagcac
     5521 aaaaattttc agagatggtc aatgatgctg taaagggtgg cgttagtcat tttattatta
     5581 atagtggcta tcgagacttt gatgagcaaa gtgtgcttta ccaagaaatg ggggctgagt
     5641 atgccttacc agcaggttat agtgagcata attcaggttt atcactagat gtaggatcaa
     5701 gcttgacgaa aatggaacga gcccctgaag gaaagtggat agaagaaaat gcttggaaat
     5761 acgggttcat tttacgttat ccagaggaca aaacagagtt aacaggaatt caatatgaac
     5821 catggcatat tcgctatgtt ggtttaccac atagtgcgat tatgaaagaa aagaatttcg
     5881 ttctcgagga atatatggat tacctaaaag aagaaaaaac catttctgtt agtgtaaatg
     5941 gggaaaaata tgagatcttt tattatcctg ttactaaaaa taccaccatt catgtgccga
     6001 ctaatcttcg ttatgagata tcaggaaaca atatagacgg tgtaattgtg acagtgtttc
     6061 ccggatcaac acatactaat tcaaggaggt aaggatggcg gaatgaaacc aacgaaatta
     6121 atgaacagca ttattgtact agcacttttg gggtaacgtt agctttttaa tttaaaaccc
     6181 acgttaacta ggacattgct atactaatga tacaacttaa acaaaagaat tagaggaaat
     6241 tatattggga aaaatattat ctagaggatt gctagcttta tatttagtga cactaatctg
     6301 gttagtgtta ttcaaattac aatacaatat tttatcagta tttaattatc atcaaagaag
     6361 tcttaacttg actccattta ctgctactgg gaatttcaga gagatgatag ataatgttat
     6421 aatctttatt ccatttggct tgcttttgaa tgtcaatttt aaagaaatcg gatttttacc
     6481 taagtttgct tttgtactgg ttttaagtct tacttttgaa ataattcaat ttatcttcgc
     6541 tattggagcg acagacataa cagatgtaat tacaaatact gttggaggct ttcttggact
     6601 gaaattatat ggtttaagca ataagcatat gaatcaaaaa aaattagaca gagttattat
     6661 ttttgtaggt atacttttgc tcgtattatt gctcgtttac cgtacccatt taagaataaa
     6721 ttacgtgtaa gatgtctaaa tcaagcaatc tgatctttca tacacataaa gatattgaat
     6781 gaattggatt agatggaaaa cgggatgtgg ggaaactcgc ccgtaggtgt gaagtgaggg
     6841 gaaaaccggt gataaagtaa aaagcttacc taacactata gtaacaaaga aagcccaatt
     6901 atcaatttta gtgctgagga attggtctct ttaataaatt tccttaacgt tgtaaatccg
     6961 cattttcctg acggtacccc ataaaggaga ataaataaaa tgaataaggt acatgtatat
     7021 aatcataata aatttgtaaa agaaattaat agcgacacga atagc
//
LOCUS       DAXLPY010000272         5706 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.113, whole genome shotgun sequence.
ACCESSION   DAXLPY010000272 DAXLPY010000000
VERSION     DAXLPY010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.113"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(152..1093)
                     /locus_tag="ACF3UF_002946"
     CDS             complement(152..1093)
                     /locus_tag="ACF3UF_002946"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFD3672951.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1219..2340
                     /locus_tag="ACF3UF_002947"
     CDS             1219..2340
                     /locus_tag="ACF3UF_002947"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFD3672952.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            2598..4100
                     /gene="eat(A)"
                     /locus_tag="ACF3UF_002948"
     CDS             2598..4100
                     /gene="eat(A)"
                     /locus_tag="ACF3UF_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFD3672953.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4167..4694
                     /locus_tag="ACF3UF_002949"
     CDS             4167..4694
                     /locus_tag="ACF3UF_002949"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3672954.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            4905..>5706
                     /locus_tag="ACF3UF_002950"
     CDS             4905..>5706
                     /locus_tag="ACF3UF_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFD3672955.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARD"
BASE COUNT         1874 a         1013 c         1216 g         1603 t
ORIGIN      
        1 aaaaaaccta cattttgaag agattatgta ctgaaacaaa caagcacaat tcttatggca
       61 tcatgagagt tgtgttttct ttttgatctt ttattgggct taaaaaaaga gaaccagctg
      121 ctgattcagc tgattctcat cagagagcct tttattctgc gccaaggatt ccttcttttg
      181 catggactaa ttgggtcaaa aaggcacaat atggtgtagc aatatcatat ttttgtcctt
      241 ttcgccaaat ggcaccattg atgtagtcga tttcagtcaa acgatggttt ttgatcaggt
      301 cttggtacat agatgggtaa tgcaacccga tgttgtcagg atcataagta gaagcaatat
      361 gttggtacac ttcttcttga tctagtatga ttccttcttt tgctgcgata gaagcaaatt
      421 cagatacgat tgttcgaacc atgctctctg ccgctttttg cgcgcctagt tcagcaatat
      481 tacaatccaa aatcgtgcat aaaccattca atgttccatt tacacaagct tttcgccaaa
      541 tggaataacg aacgttatgg ctatagatcg gatttaaatt tgcttcttga aagacttcta
      601 caactttttt tgtaaatgct tcgccttctg gttccaagtt ctctagttcg atttctccat
      661 cacctaacaa tgtgactttt ccgggaccag ctagaccagc tgtccacatc gtgatcccaa
      721 ataagatatt tttctttggc acatattttt ccagtacatc ttcatgacct aatccattta
      781 gtaaacacaa aacataagta ttgtcagtaa taatggattg gatcgaacaa aacatatcat
      841 ctaattgatt ggcttttgtt aatgctacga tcaagtccac gtgttcgttg ctttcgatga
      901 tttcttctgg tgaatagatt ggcagttttg cgaccacttc tttaccgtta aagtcagcaa
      961 tcaacccatt tgtacgaatg gcttcaatgt gagcaggcca acgatcgatc aagaggacct
     1021 catttccgct ttgatgtagc atcaatccga ttcggctgcc cattgctccg gccccagcta
     1081 ttgcgatttt catgtttttt ctctccttta ttcaatgagt tcccttttag tatatagaaa
     1141 aatggaagaa aatagcattg ttttgtttga aaaaaatgaa aaaaagtgtc ttacttaaga
     1201 agaaagtgag ggatacagat ggatattttg gcggcaattg attcatttaa aggaagtgct
     1261 tcttcatttg aactaaatca ggcagttcta aatggctggg aagatcgtaa aggaagaaaa
     1321 atcaatgtgc cgattgcaga tggcggagaa aatactgcag aagcaatcta ttacgcgctc
     1381 aggggaacat ggcgtaccat tgatgggatg gatctcttat tccgtcagcg aaaaatcagc
     1441 tatttattga caacttggca aggaaaaaac accgcagtca tcgaatctgc acaagcattg
     1501 gggttagatc tacttgataa accaacggat caaactatcc gacttgcttc cagttatgcc
     1561 ttaggagaac ttattaaaga tgcactgctt caagaagtag aacaaattat tgtcacttta
     1621 ggaggaagcg ggtgtagcga tggtggtcta ggattactcc aatccttggg tgcttcttta
     1681 gaagggtaca cagaaggaaa tcctttatta tctactaaaa aacttcattt tgatcgaaga
     1741 aacgttcttg tttctaaagt aaaattgatt atcgctgcag atgttaccaa tccatataca
     1801 ggtcaacaag gagctgcttg gcaatttgga agacaaaaag gaggaataga tacgacgcta
     1861 gctttcttag ataaacaagc aggaaagatt gctcagcaaa taaaagattt ctgggaggtg
     1921 gatttagatg atattccagg aagtggagca gcaggcggta ttggtggagc cctttttttg
     1981 ttgggagcga agatggtttc tggtttcgat ttagtcagcc aaatcactgg attggaaaaa
     2041 aagatcgaac aagcagatgt catcattaca ggagaagggc ggatcgatca gcaaacgatc
     2101 cacggaaaag ttccatacgg tgtagcagtg cttgcaaaaa aatatcgaaa accaataatc
     2161 gctatttgcg gaagtagaga ccaagagcta gaaggacttt ctgattttct cccaattgtc
     2221 ttaagtattc atttgggtcc aataggttta gaagaagcaa tggaacacag gcaaacatta
     2281 gaaaaaacaa aaatcttagg acagacactt agcagatttt tcaccatcct cccgaagtag
     2341 ttgacaaaat cattttcttt atgctatcgt aatttcaaat ataggacaaa gtgagggatc
     2401 cgtgcattga aaaattaagt cgattgatga aagctgcatt cagactgtac cttgtggaga
     2461 caaggaagca gtgtgcagat tttcgggatt ggcttggttt tttcgatgta tgggtctttt
     2521 tgtgtgtatc caacccttgc atcctcttta gccagttctg aaaataggac tggtcttttt
     2581 ttacgaggtg atggaaaatg tctaaaatcg aaataaaaaa tctgacattc ggctacgaca
     2641 gccaaggcac attattattt gaacaagcaa atctaaattt tgacacacaa tggaaactag
     2701 gacttatcgg acgaaacggt cgaggaaaga caactttact gaatattcta caaaacaaac
     2761 taccttatca agggcaagta atccatcagc aagaatttgc ctatttcccg caacagacaa
     2821 aagataaaga acgtttaacc tattacgtgt taaatgatat tacggatttt gagatatggg
     2881 aaatcgaaag agagctccaa ttgatgcaaa cagatcctga aatcttatgg agagaattca
     2941 gcacactatc ggggggagag aagacaaaag tcctactggc acttttattt gtggatgaca
     3001 ctcatttccc gttaatcgat gaaccaacga atcatttgga tatctctggt agaaaacaag
     3061 tagcggctta tttgaaaaag aaaaaacaag gcttcatcgt ggtcagccat gaccggggat
     3121 ttatcgatga agtagtggac catgttttag caatcgaaaa aagtcaactg gaactttatc
     3181 aagggaattt ctctatctat gaagaacaga aaaaacttcg tgatgaattt gaaatggctc
     3241 aaaatgaaaa attgaaaaaa gaagtcagta ggctaaagaa aacagcagct gaaaaagccg
     3301 aatggtctcg ttcccgagaa ggagataaaa caaagaaaca agtcggattc atcgatactg
     3361 aatctagacg agtgaataaa ggagcagtgg gtgctgatgc tgcacggacg atgaaacgat
     3421 ccaaagcaat cgtgaatcgg atggagaccc agatcagcga gaaagaaaaa ctattaaaag
     3481 atatcgaata tatcgattct ttgacgatga atagccaagc gtctcaccat aagcgacttt
     3541 taagcgtaga agatcttcaa ttagggtatg aaaatctgtt attcgagcca attcatttta
     3601 caatcgagcc tcatcagcgg gtggcgattt caggtcctaa cggtgcagga aagtcatcca
     3661 ttatccatta tcttctgggg gcattcaacg gcaaggttat aggagaaaaa taccagccaa
     3721 aacatctgag cattagttat gcaagccaaa attatgaaga caatcgagga acgttggcgg
     3781 aatttgcaga gaaaaaccaa gtagactacc aagcattttt gaacaacctc cgaaagcttg
     3841 ggatggaaag agatgttttt cataacaaga tcgagcagat gagtatgggc caacggaaaa
     3901 aagtggaatt ggctaaatct ttatcacagc cagctgaact atatacatgg gatgaaccat
     3961 tgaattattt ggatgtcttc aatcaagaac aattagaaca actgatcttg aacgtgaaac
     4021 ctgccatgtt actagtggaa catgatcaaa ccttcctgga taaagtatct actgagatta
     4081 tttctcttga gagaatctaa cccttgtaat ctcaagaaca acaaggtatg gttaagggga
     4141 actttgccaa cgaaggagag aatcacatgc tttatgtaac gagacacgga gaaacaactt
     4201 ggaacgcaca aggattagtt tgcggacggg cagatgtgcc gctgactgaa aaaggacaga
     4261 tgcaggcaca gaaactagca gaaaaggtag tagatttgcc tgttccaatc acgaaaatca
     4321 tccattcccc tcttcaacga gcaagagata cagcacaagc agttgctgat cgtctcagct
     4381 tgccgctgac cgttgatgaa cgattggtag aaatggattt tggggattat gatggactgc
     4441 caagcaaaga tgagaacttt caaaaagcac gtttagcgtt cgctgtacga ttcccaaatg
     4501 gggagtcagt cttagatgtg tatgcacgga tcgttccttt attgaaagaa tgcatcgaag
     4561 acgaagaaaa tgtctatctg ttagtttgcc ataatgcctt gataagagtg atcaatgctt
     4621 attttcatcc gatgcctaat gaggggttct ttacattcat ggtagataat acagaattgg
     4681 tttcttatga gtaattatgt ttttgtgtta tttaaataaa atatttcaag gcactgcttt
     4741 tgcttagcag tgcctttttt aggttatgac aattcttttg ataatataaa ctcaaccttt
     4801 agaaatgaaa tttaattatt ttaataaaag tattgaaatt ttgtttcttt agatatatac
     4861 tctagtcata gaaatgaaga cggatacaga aaaagaggga taatatgttt ggcttttcaa
     4921 tatttatgaa cgattctttg tcagaagaga agaaacagta tatccgccaa atggcatcca
     4981 atggctttgt cggtattttc acttccatgc atataccaga agatgatgtt tcggcatatc
     5041 aaaagcgatt gatcgaacta ggaagcgaag cgaaaaagaa taaactagaa ttgatggtcg
     5101 atatttcagg agaggcattg gaacgagcgg gtttttcatt agaagatcta acgcctttga
     5161 aagcaattgg tgtaacaggt ttaagaatgg attatcatat ttccaatcag cagattgccg
     5221 actggtcaca tcaattgaaa atcagtttga atgctagcac gatcacgcct aaagatatcg
     5281 atgaattgaa agaagcagaa gctgatttct cacagattga agcttggcat aattattatc
     5341 cacgtcccga aacagggctg gacaaagaat ggtatcagaa aaaaaatcaa tggctcaaaa
     5401 ttcaaggtct ccttgtccaa ggttttgtac caggagatac agagttgaga ggcccactat
     5461 atcaaggatt gccaactttg gaagaacatc gagggatcca tcctcttgca ggcgctctag
     5521 atctattagc aagtaacacg gatattgttt acatcggaga tgcaggtctg tcagaaaacg
     5581 ttcaggagca atttgcttct ttccaaaaag aacagacagt cttgctccat acggaacctg
     5641 tagatgaaga attttacgaa tatatattag ggaagcatac gaatcggcaa gacgatgcaa
     5701 gagatg
//
LOCUS       DAXLPY010000273         3719 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.133, whole genome shotgun sequence.
ACCESSION   DAXLPY010000273 DAXLPY010000000
VERSION     DAXLPY010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.133"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(530..655)
                     /locus_tag="ACF3UF_002951"
     CDS             complement(530..655)
                     /locus_tag="ACF3UF_002951"
                     /inference="COORDINATES: protein motif:HMM:NF019687.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672956.1"
                     /translation="MLFPPFKSSKSRKNPSDKYSYHWDFNTKIAVYYTLIATDAL"
     gene            640..2580
                     /gene="tet(S)"
                     /locus_tag="ACF3UF_002952"
     CDS             640..2580
                     /gene="tet(S)"
                     /locus_tag="ACF3UF_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HFD3672957.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVRHMFNKINLH"
     gene            2668..2835
                     /locus_tag="ACF3UF_002953"
     CDS             2668..2835
                     /locus_tag="ACF3UF_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFD3672958.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(3349..3705)
                     /locus_tag="ACF3UF_002954"
     CDS             complement(3349..3705)
                     /locus_tag="ACF3UF_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3672959.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLT
                     NIENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVT
                     IGKVIQAIYGEKCKFN"
BASE COUNT         1327 a          577 c          618 g         1197 t
ORIGIN      
        1 atttgatagt agatttaaaa ctttgcaaca gaaccctttt aatgatattt tccaagtcaa
       61 acttaatatt aacaattcaa aactattgga accactgcaa aatattttgt taagcagtat
      121 atatttcaaa aattatacgt aatatatttg tagaaaggtt gtggacagtt gtcctattga
      181 cctgaaaagt aatataatag ctggatgaat aaagaatccc ttatgaactt gtaaatcgtt
      241 attaaatcgc tgaattttga tagccattct gaagagttat cttcaactac tacactaact
      301 tccattaatt tctcattaat ttccctttcg ttcaaaaaat atggttggct ttacaagcat
      361 tctatcatat gatagaatta agataacatt caaaaggaga taataaaaat gcggcaaggt
      421 attcttaaat aaactgtcaa ttagatagcg ggaataatta attaagcatc cttatttaaa
      481 ataaggactg gttttttgtg cccagtttaa gaatactttt atcattttat cataaagcat
      541 ctgtggctat cagtgtgtag tatacagcta tttttgtatt aaaatcccag tgataagagt
      601 atttatcact gggatttttt ctgctttttg agcttttgaa tggaggaaat aaaattgaaa
      661 attattaata tcggtatctt agcacatgtt gatgcaggaa aaactacttt gacagaaagc
      721 ttactataca gtagcggagc aattaaagag ttaggaagtg tagatagcgg tacaacgaaa
      781 acggatacta tgtttttgga acgccagaga ggtattacta ttcagaccgc aataacatct
      841 tttcaacggg aaaatgttaa agtaaatatt gtagatactc ctggacacat ggattttttg
      901 gcagatgtat accgttcatt atctgttttg gatggagcta ttttgctaat ctctgcaaaa
      961 gatggagtac agtcacaaac tcgtatacta ttccatgcac ttagaaagat gaacatacct
     1021 ataatatttt ttattaacaa aattgatcaa aatggaataa atttgccaga tgtttatcaa
     1081 gatattaagg acaaactttc tgacgacatc ataattaagc agactgtgaa tctaaatttg
     1141 aaaccttatg taatagatta tactgaacca gaacaatggg agacagtaat tgtgggaaat
     1201 gattatttat tagaaaaata taccattggg aaaacattga atattgcaga acttgaaaag
     1261 gaggaaaacg aaagaattca aagttgctcc ttatatcctg tttatcacgg aagtgcaaag
     1321 aataatattg gaattaaaca acttatagag gtaattacta gcaaattatt ttcacccaca
     1381 caactcaatt cagataaact ttgtggaaat gtttttaaag tagaatattc agatgatggt
     1441 caacggcttg tctatgtacg tctttatagt ggaacgctac atttgcgaga ctcagtcaat
     1501 atatcagaaa aggaaaaaat aaaagttaca gaaatgtata cttcaataaa tggagaatta
     1561 cgccagatag ataaggcaga gcctggtgag attattattt taaaaaatga gcttttaaaa
     1621 ctaaataacg tacttggaga taaaaaaaga ttaccacata gagaaattct tgagaatcct
     1681 cttcctatgt tacaaacaac aattgaacca tgtaaatcag tacaaagaga aaagttacta
     1741 gatgcacttt ttgaaatatc cgatagtgat ccccttctac aatattatgt agatacagta
     1801 actcacgaaa ttgtgctatc ttttttaggt gaggtccaaa tggaggtaac ttgtactctg
     1861 attcaagaaa aatatcatat tgagatagaa acaagaaaac caactgtcat ttatatggaa
     1921 agaccattaa aaaaatctga atttaccatt gatatcgaag tacctccaaa tcctttctgg
     1981 gcttctattg gtttatctgt aacaccactt cctttgggta gtggcattca gtatgagagc
     2041 ctggtttctc taggttattt aaatcaatca tttcaaaatg cagttatgga aggtatacgc
     2101 tatgggtgtg aacaaggatt gtacggttgg aaattaacag actgtaagat ctgttttaag
     2161 tatggtctat attacagccc tgtcagtacg ccagcagatt tccgaatgct tgcgcctatt
     2221 gtactagagc aggcttttag aaagagtggt acagagttat tagagccata tcttagcttc
     2281 gaaatttatg taccacaaga atatctttcg agagcatata atgatgcttc caaatattgt
     2341 gcaaatattt taaatactaa gttaaaaggt aacgaggtca ttctcattgg tgaaattcca
     2401 gcccgttgta ttcaagagta tcgaaacagt ttaactttct ttacaaatgg acgcagtgtc
     2461 tgtttaacag agttaaaagg ttatcaggtt actaacatta agtctgcttt ccaaccacgt
     2521 cgtccaaata atagaataga caaagtaagg catatgttta ataaaatcaa cttacattga
     2581 tagtgaacta aagagaaatt tttaaaatga atattgagtt gttaattaga acaggaggat
     2641 atagatattg taaatactag gtggatactg tgccctatat gtggcaataa gacccgttta
     2701 aaaatgaggg aagatactga attaaaaaat ttccctctat tttgtcctaa atgcagacaa
     2761 gaaattttaa ttgaaataac gaagtttaga ataactgtaa ttacagagcc agacgcaaag
     2821 acgcagagcc gataattcga gatatcaaaa tctcatttta tcggcttttt cttttctatg
     2881 cataccattg agcttagttc ttgatatcct ttataagaaa ataagtgtac tgattttttt
     2941 tgcagtagct gtattacagt agacatccct caagcataaa aagtatacaa ttaaaattca
     3001 atacttgatt attgatgaag tacagagtta ctcgtcattt caaaactagt atatcagtca
     3061 agtttttcct aaggaacaaa aacgaacttc gctatgggaa tcaaaaattt ttagtcggat
     3121 gaagtgatat gcaataaatc cagaaaattt tcccaacaac aaaaaatgaa ctgtactttg
     3181 cagcgataag agtaaccaaa gaactattta tcattcgctc tagttcctaa gtgtaacaaa
     3241 gataaattca ttttctattt atgattaaca aaaatcagaa aaaattcatt acatctttgt
     3301 aatcaatctt tcctgatagt attaattaat ccattgtgta ttattgaact agttaaattt
     3361 acatttttct ccgtaaattg cttgaatcac tttcccaatc gtcactaatt catcttcatc
     3421 cagacaatcc aactgtgctt ctacttgaag acgtttggag cttttatgac tgttttcttc
     3481 ccctaaaata aatccatcca aagaaatatt tagcaaagtc actaaatcat atacaacatg
     3541 aaaacttggc tgttgtcctt tattttcaat gttcgtcaaa tagcgtggcg caatctggat
     3601 cattgatcct acctgctcac gagtcaatcc tttactaaga cgggcttctt taatcgcaag
     3661 acccaatggt ttgaaatcaa aatttgatag agtagtttgc catattcttg cacccaacg
//
LOCUS       DAXLPY010000274         3612 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.136, whole genome shotgun sequence.
ACCESSION   DAXLPY010000274 DAXLPY010000000
VERSION     DAXLPY010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3612
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.136"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..693
                     /locus_tag="ACF3UF_002955"
     CDS             <1..693
                     /locus_tag="ACF3UF_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672960.1"
                     /translation="EIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQ
                     LKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSR
                     IDKVRYMFNKIT"
     gene            800..853
                     /locus_tag="ACF3UF_002956"
                     /pseudo
     CDS             800..853
                     /locus_tag="ACF3UF_002956"
                     /inference="COORDINATES: protein motif:HMM:NF019662.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            887..2263
                     /gene="tet(L)"
                     /locus_tag="ACF3UF_002957"
     CDS             887..2263
                     /gene="tet(L)"
                     /locus_tag="ACF3UF_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFD3672961.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2827..>3612
                     /gene="mobV"
                     /locus_tag="ACF3UF_002958"
     CDS             2827..>3612
                     /gene="mobV"
                     /locus_tag="ACF3UF_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HFD3672962.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKGFCCKVLNLLSN"
BASE COUNT         1149 a          549 c          743 g         1171 t
ORIGIN      
        1 gagatagaac taaaagagcc tacagtcatt tatatggaga gaccgttaaa aaatgcagaa
       61 tataccattc acatcgaagt gccgccaaat cctttctggg cttccattgg tttatctgta
      121 tcaccgcttc cgttgggaag tggaatgcag tatgagagct cggtttctct tggatactta
      181 aatcaatcat ttcaaaatgc agttatggaa gggatacgct atggttgcga acaaggatta
      241 tatggttgga atgtgacgga ttgtaaaatc tgttttaagt atggcttata ctatagccct
      301 gttagtaccc cagcagattt tcggatgctt gctcctattg tattggaaca agtcttaaaa
      361 aaagctggaa cagaattgtt agagccatat cttagtttta aaatttatgc gccacaggaa
      421 tatctttcac gagcatacaa cgatgctcct aaatattgtg cgaacatcgt agacactcaa
      481 ttgaaaaata atgaggtcat tcttagtgga gaaatccctg ctcggtgtat tcaagaatat
      541 cgtagtgatt taactttctt tacaaatgga cgtagtgttt gtttaacaga gttaaaaggg
      601 taccatgtta ctaccggtga acctgtttgc cagccccgtc gtccaaatag tcggatagat
      661 aaagtacgat atatgttcaa taaaataact tagtgtattt tatgttgtta tataaatatg
      721 gtttcttgtt aaataagatg aaatattttt taataaagat ttgaattaaa gtgtaaagga
      781 ggaattaatt atgaagtgaa atgaatgtaa cagggttcaa ttaaaagagg gaagcgtatc
      841 attaacccta taaactacgt ctgccctcat tattggaggg tgaaatgtga atacatccta
      901 ttcacaatcg aatttacgac acaaccaaat tttaatttgg ctttgcattt tatctttttt
      961 tagcgtatta aatgaaatgg ttttgaacgt ctcattacct gatattgcaa atgattttaa
     1021 taaaccacct gcgagtacaa actgggtgaa cacagccttt atgttaacct tttccattgg
     1081 aacagctgta tatggaaagc tatctgatca attaggcatc aaaaggttac tcctatttgg
     1141 aattataata aattgtttcg ggtcggtaat tgggtttgtt ggccattctt tcttttcctt
     1201 acttattatg gctcgtttta ttcaaggggc tggtgcagct gcatttccag cactcgtaat
     1261 ggttgtagtt gcgcgctata ttccaaagga aaataggggt aaagcatttg gtcttattgg
     1321 atcgatagta gccatgggag aaggagtcgg tccagcgatt ggtggaatga tagcccatta
     1381 tattcattgg tcctatcttc tactcattcc tatgataaca attatcactg ttccgtttct
     1441 tatgaaatta ttaaagaaag aagtaaggat aaaaggtcat tttgatatca aaggaattat
     1501 actaatgtct gtaggcattg tattttttat gttgtttaca acatcatata gcatttcttt
     1561 tcttatcgtt agcgtgctgt cattcctgat atttgtaaaa catatcagga aagtaacaga
     1621 tccttttgtt gatcccggat tagggaaaaa tatacctttt atgattggag ttctttgtgg
     1681 gggaattata tttggaacag tagcagggtt tgtctctatg gttccttata tgatgaaaga
     1741 tgttcaccag ctaagtactg ccgaaatcgg aagtgtaatt attttccctg gaacaatgag
     1801 tgtcattatt ttcggctaca ttggtgggat acttgttgat agaagaggtc ctttatacgt
     1861 gttaaacatc ggagttacat ttctttctgt tagcttttta actgcttcct ttcttttaga
     1921 aacaacatca tggttcatga caattataat cgtatttgtt ttaggtgggc tttcgttcac
     1981 caaaacagtt atatcaacaa ttgtttcaag tagcttgaaa cagcaggaag ctggtgctgg
     2041 aatgagtttg cttaacttta ccagcttttt atcagaggga acaggtattg caattgtagg
     2101 tggtttatta tccataccct tacttgatca aaggttgtta cctatggaag ttgatcagtc
     2161 aacttatctg tatagtaatt tgttattact tttttcagga atcattgtca ttagttggct
     2221 ggttaccttg aatgtatata aacattctca aagggatttc taaatcgtta agggatcaac
     2281 tttgggagag agttcaaaat tgatcctttt tttataacag gaattcaaat ctttttgttc
     2341 cattaaaggg cgcgattgct gaataaaaga tacgagagac ctctcttgta tcttttttat
     2401 tttgagtggt tttgtccgtt acactagaaa accgaaagac aataaaaatt ttattcttgc
     2461 tgagtctggc tttcggtaag ctagacaaaa cggacaaaat aaaaattggc aagggtttaa
     2521 aggtggagat tttttgagtg atcttctcaa aaaatactac ctgtcccttg ctgattttta
     2581 aacgagcacg agagcaaaac ccccctttgc tgaggtggca gagggcaggt ttttttgttt
     2641 cttttttctc gtaaaaaaaa gaaaggtctt aaaggtttta tggttttggt cggcactgcc
     2701 gacagcctcg cagagcacac actttatgaa tataaagtat agtgtgttat actttacttg
     2761 gaagtggttg ccggaaagag cgaaaatgcc tcacatttgt gccacctaaa aaggagcgat
     2821 ttacatatga gttatgcagt ttgtagaatg caaaaagtga aatcagctgg actaaaaggc
     2881 atgcaatttc ataatcaaag agagcgaaaa agtagaacga atgatgatat tgaccatgag
     2941 cgaacacgtg aaaattatga tttgaaaaat gataaaaata ttgattacaa cgaacgtgtc
     3001 aaagaaatta ttgaatcaca aaaaacaggt acaagaaaaa cgaggaaaga tgctgttctt
     3061 gtaaatgagt tgctagtaac atctgaccga gatttttttg agcaactgga tccaggagaa
     3121 caaaaacgat tttttgagga aagttataaa ttattttccg aacgatatgg caagcaaaat
     3181 attgcttatg caacagttca taatgatgag caaacccctc acatgcattt aggtgttgtg
     3241 cctatgcgtg atggaaaact gcaaggaaaa aatgtgttta atcgtcaaga actgttatgg
     3301 ctacaagata aattccccga gcatatgaaa aaacagggtt ttgagttgaa gcgtggtgaa
     3361 cgtggctctg accgtaaaca tattgagaca gctaaattta aaaaacaaac tttggaaaaa
     3421 gagattgatt ttctagaaaa aaatttagca gttaaaaaag atgaatggac tgcttatagc
     3481 gataaagtta aatcagattt agaagtacca gcgaaacgac acatgaaaag tgttgaagtg
     3541 ccaacgggtg aaaagtccat gtttggtttg ggaaaagggt tctgttgcaa agttttaaat
     3601 ctactatcaa at
//
LOCUS       DAXLPY010000275         2610 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.148, whole genome shotgun sequence.
ACCESSION   DAXLPY010000275 DAXLPY010000000
VERSION     DAXLPY010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.148"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(530..655)
                     /locus_tag="ACF3UF_002959"
     CDS             complement(530..655)
                     /locus_tag="ACF3UF_002959"
                     /inference="COORDINATES: protein motif:HMM:NF019687.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672963.1"
                     /translation="MLFPPFKSSKSRKNPSDKYSYHWDFNTKIAVYYTLIATDAL"
     gene            640..2592
                     /gene="tet(S)"
                     /locus_tag="ACF3UF_002960"
     CDS             640..2592
                     /gene="tet(S)"
                     /locus_tag="ACF3UF_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HFD3672964.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVRHMFNKINGSVAKF"
BASE COUNT          940 a          386 c          453 g          831 t
ORIGIN      
        1 atttgatagt agatttaaaa ctttgcaaca gaaccctttt aatgatattt tccaagtcaa
       61 acttaatatt aacaattcaa aactattgga accactgcaa aatattttgt taagcagtat
      121 atatttcaaa aattatacgt aatatatttg tagaaaggtt gtggacagtt gtcctattga
      181 cctgaaaagt aatataatag ctggatgaat aaagaatccc ttatgaactt gtaaatcgtt
      241 attaaatcgc tgaattttga tagccattct gaagagttat cttcaactac tacactaact
      301 tccattaatt tctcattaat ttccctttcg ttcaaaaaat atggttggct ttacaagcat
      361 tctatcatat gatagaatta agataacatt caaaaggaga taataaaaat gcggcaaggt
      421 attcttaaat aaactgtcaa ttagatagcg ggaataatta attaagcatc cttatttaaa
      481 ataaggactg gttttttgtg cccagtttaa gaatactttt atcattttat cataaagcat
      541 ctgtggctat cagtgtgtag tatacagcta tttttgtatt aaaatcccag tgataagagt
      601 atttatcact gggatttttt ctgctttttg agcttttgaa tggaggaaat aaaattgaaa
      661 attattaata tcggtatctt agcacatgtt gatgcaggaa aaactacttt gacagaaagc
      721 ttactataca gtagcggagc aattaaagag ttaggaagtg tagatagcgg tacaacgaaa
      781 acggatacta tgtttttgga acgccagaga ggtattacta ttcagaccgc aataacatct
      841 tttcaacggg aaaatgttaa agtaaatatt gtagatactc ctggacacat ggattttttg
      901 gcagatgtat accgttcatt atctgttttg gatggagcta ttttgctaat ctctgcaaaa
      961 gatggagtac agtcacaaac tcgtatacta ttccatgcac ttagaaagat gaacatacct
     1021 ataatatttt ttattaacaa aattgatcaa aatggaataa atttgccaga tgtttatcaa
     1081 gatattaagg acaaactttc tgacgacatc ataattaagc agactgtgaa tctaaatttg
     1141 aaaccttatg taatagatta tactgaacca gaacaatggg agacagtaat tgtgggaaat
     1201 gattatttat tagaaaaata taccattggg aaaacattga atattgcaga acttgaaaag
     1261 gaggaaaacg aaagaattca aagttgctcc ttatatcctg tttatcacgg aagtgcaaag
     1321 aataatattg gaattaaaca acttatagag gtaattacta gcaaattatt ttcacccaca
     1381 caactcaatt cagataaact ttgtggaaat gtttttaaag tagaatattc agatgatggt
     1441 caacggcttg tctatgtacg tctttatagt ggaacgctac atttgcgaga ctcagtcaat
     1501 atatcagaaa aggaaaaaat aaaagttaca gaaatgtata cttcaataaa tggagaatta
     1561 cgccagatag ataaggcaga gcctggtgag attattattt taaaaaatga gcttttaaaa
     1621 ctaaataacg tacttggaga taaaaaaaga ttaccacata gagaaattct tgagaatcct
     1681 cttcctatgt tacaaacaac aattgaacca tgtaaatcag tacaaagaga aaagttacta
     1741 gatgcacttt ttgaaatatc cgatagtgat ccccttctac aatattatgt agatacagta
     1801 actcacgaaa ttgtgctatc ttttttaggt gaggtccaaa tggaggtaac ttgtactctg
     1861 attcaagaaa aatatcatat tgagatagaa acaagaaaac caactgtcat ttatatggaa
     1921 agaccattaa aaaaatctga atttaccatt gatatcgaag tacctccaaa tcctttctgg
     1981 gcttctattg gtttatctgt aacaccactt cctttgggta gtggcattca gtatgagagc
     2041 ctggtttctc taggttattt aaatcaatca tttcaaaatg cagttatgga aggtatacgc
     2101 tatgggtgtg aacaaggatt gtacggttgg aaattaacag actgtaagat ctgttttaag
     2161 tatggtctat attacagccc tgtcagtacg ccagcagatt tccgaatgct tgcgcctatt
     2221 gtactagagc aggcttttag aaagagtggt acagagttat tagagccata tcttagcttc
     2281 gaaatttatg taccacaaga atatctttcg agagcatata atgatgcttc caaatattgt
     2341 gcaaatattt taaatactaa gttaaaaggt aacgaggtca ttctcattgg tgaaattcca
     2401 gcccgttgta ttcaagagta tcgaaacagt ttaactttct ttacaaatgg acgcagtgtc
     2461 tgtttaacag agttaaaagg ttatcaggtt actaacatta agtctgcttt ccaaccacgt
     2521 cgtccaaata atagaataga caaagtaagg catatgttta ataaaatcaa cggttctgtt
     2581 gcaaagtttt aaataaagaa taaaatccct
//
LOCUS       DAXLPY010000276         2558 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.153, whole genome shotgun sequence.
ACCESSION   DAXLPY010000276 DAXLPY010000000
VERSION     DAXLPY010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.153"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..173
                     /locus_tag="ACF3UF_002961"
     CDS             <1..173
                     /locus_tag="ACF3UF_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3672965.1"
                     /translation="KYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMDIPGMADEMRR
                     PMMLIVSAKKKM"
     gene            206..1114
                     /locus_tag="ACF3UF_002962"
     CDS             206..1114
                     /locus_tag="ACF3UF_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFD3672966.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1111..1653
                     /gene="sat4"
                     /locus_tag="ACF3UF_002963"
     CDS             1111..1653
                     /gene="sat4"
                     /locus_tag="ACF3UF_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFD3672967.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            1746..2540
                     /locus_tag="ACF3UF_002964"
                     /note="aph(3')-IIIa"
     CDS             1746..2540
                     /locus_tag="ACF3UF_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFD3672968.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          872 a          398 c          603 g          685 t
ORIGIN      
        1 caaaatatca tagaacactg accacatatc taaatacact gctttcaaat agttttataa
       61 taaatcagat tgtggagcca cagccgccag agaacatgat ggatattccg gggatggcgg
      121 atgaaatgcg acgcccaatg atgctgattg tatcggcaaa aaagaagatg taataatata
      181 gaaaaaataa acgaggagta tgtaaatgag atcagaaaaa gaaatgatgg atttagtact
      241 ttctttagca gaacaggatg aacgtattcg aattgtgacc cttgaggggt cacgcgcaaa
      301 tattaatata cctaaagatg aatttcagga ttatgatatt acatattttg taagtgatat
      361 agaaccgttt atatctaatg atgactggct taatcaattt gggaatataa taatgatgca
      421 aaagccggag gatatggaat tattcccacc tgaagaaaag ggattttcct atcttatgct
      481 atttgatgat tacaataaaa ttgatcttac cttattgccc ttggaagagt tagataatta
      541 cctaaagggc gataaattaa taaaggttct aattgataaa gattgtagaa ttaaaaggga
      601 catagttccg actgatatag attatcatgt aagaaagcca agcgcaaggg agtatgatga
      661 ttgctgcaat gaattttgga atgtaacacc ttatgttatt aaaggattgt gccgtaagga
      721 aattttattt gctattgatc attttaatca gattgttcgc catgagctgc tgagaatgat
      781 atcatggaag gtcggcatcg aaacaggctt taaattaagt gtaggcaaga actataagtt
      841 tattgaaagg tatatatccg aggatttgtg ggagaaactt ttgtccacct accggatgga
      901 ttcctatgaa aacatatggg aagcattatt tctatgccat caattgttca gggcggtatc
      961 cggtgaggtg gcggaaaggc ttcattatgc ctatccggag tatgatagga atataacaaa
     1021 atataccagg gacatgtata aaaaatacac tggtaaaacc ggctgcctgg atagcacata
     1081 tgccgctgat atagaagaga ggcgggaaca gtgattacag aaatgaaagc agggcacctg
     1141 aaagatatcg ataaacccag cgaaccattt gaggtgatag gtaagattat accgaggtat
     1201 gaaaacgaga attggacctt tacagaatta ctctatgaag cgccatattt aaaaagctac
     1261 caagacgaag aggatgaaga ggatgaggag gcagattgcc ttgaatatat tgacaatact
     1321 gataagataa tatatcttta ctaccaagac gataaatgcg tcggaaaagt taaactgcga
     1381 aaaaattgga accggtacgc ttatatagaa gatatcgccg tatgtaagga tttcaggggg
     1441 caaggcatag gcagcgcgct tatcaatata tctatagaat gggcaaagca taaaaacttg
     1501 catggactaa tgcttgaaac ccaggacaat aaccttatag cttgtaaatt ctatcataat
     1561 tgtggtttca aaatcggctc cgtcgatact atgttatacg ccaactttga aaacaacttt
     1621 gaaaaagctg ttttctggta tttaaggttt tagaatgcaa ggaacagtga attggagttc
     1681 gtcttgttat aattagcttc ttggggtatc tttaaatact gtagaaaaga ggaaggaaat
     1741 aataaatggc taaaatgaga atatcaccgg aattgaaaaa actgatcgaa aaataccgct
     1801 gcgtaaaaga tacggaagga atgtctcctg ctaaggtata taagctggtg ggagaaaatg
     1861 aaaacctata tttaaaaatg acggacagcc ggtataaagg gaccacctat gatgtggaac
     1921 gggaaaagga catgatgcta tggctggaag gaaagctgcc tgttccaaag gtcctgcact
     1981 ttgaacggca tgatggctgg agcaatctgc tcatgagtga ggccgatggc gtcctttgct
     2041 cggaagagta tgaagatgaa caaagccctg aaaagattat cgagctgtat gcggagtgca
     2101 tcaggctctt tcactccatc gacatatcgg attgtcccta tacgaatagc ttagacagcc
     2161 gcttagccga attggattac ttactgaata acgatctggc cgatgtggat tgcgaaaact
     2221 gggaagaaga cactccattt aaagatccgc gcgagctgta tgatttttta aagacggaaa
     2281 agcccgaaga ggaacttgtc ttttcccacg gcgacctggg agacagcaac atctttgtga
     2341 aagatggcaa agtaagtggc tttattgatc ttgggagaag cggcagggcg gacaagtggt
     2401 atgacattgc cttctgcgtc cggtcgatca gggaggatat cggggaagaa cagtatgtcg
     2461 agctattttt tgacttactg gggatcaagc ctgattggga gaaaataaaa tattatattt
     2521 tactggatga attgttttag tacctagatt tagatgtc
//
LOCUS       DAXLPY010000277         2554 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.154, whole genome shotgun sequence.
ACCESSION   DAXLPY010000277 DAXLPY010000000
VERSION     DAXLPY010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.154"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            82..288
                     /locus_tag="ACF3UF_002965"
     CDS             82..288
                     /locus_tag="ACF3UF_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672969.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(285..1388)
                     /locus_tag="ACF3UF_002966"
     CDS             complement(285..1388)
                     /locus_tag="ACF3UF_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFD3672970.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            1941..2489
                     /gene="aac(6')"
                     /locus_tag="ACF3UF_002967"
     CDS             1941..2489
                     /gene="aac(6')"
                     /locus_tag="ACF3UF_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFD3672971.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          827 a          448 c          495 g          784 t
ORIGIN      
        1 actgtgtgat acgtaaagaa catggtacag atattgatgc agcttgcgga caattgcgaa
       61 gcaagcaaat gaaaaaaaca gttgccaaat aatcgtatcc tactcgtttt ttcaattacc
      121 ataaaaggag cagttttctt aattaaggaa ctgttcaact taaataagag aaaagattct
      181 atagcgaaag ctataaagct ttttttgaca agaaaaaccc tcatcaagca aagaaatgtc
      241 ctcaatttga tgacagcctg cttgatgggg gttttagcaa ttatttaact gattttctta
      301 tatccttgct ggctttcttg tgtagcatga taagtttcta cgtcaagaat ggcctgttta
      361 aatttttctc gggtgatttc ataaggcaca tgtttaatat catttgttgc catggcttta
      421 tctaagattg cttctaaatc ggtcgtgaca ttgagattca tgtcggttaa cgatactgga
      481 agttggttct ttttcataaa cacatagatt ttatcaaaca aatcgaactg ctgatccatc
      541 atcaataagg tcagtacacc ataactgaca gatgctccgt gaaggtatcc ctccattttt
      601 tctagaacag tcgtaccgta atagaatgag tgtgccatag cagaattata gttattgtta
      661 actaaaacag aaaccaatcc ggtagtaaca atgatatccg aaacgacttg ttcaattgca
      721 tatgagggac gatcgtcggc actatctttc aatgcttgcg taccataagt caagagacga
      781 tcaatgcaca tttttccgat ttggattcct aatctatccg tgtagcctag atcatcgcca
      841 cgagcagaaa aagtagattc gacttctttg gataaagcat cgccaatacc tgcccataag
      901 tatttatcag gtgcttcggc aataattgct gtatcaatga aggtgtgtac aggtggtttt
      961 gaaggaaaga agagtccgtc cattacgcct tcttcgttat agatgacaca taccgcagtg
     1021 acgggcgaac agttcgaacc aatagtggga aaggtgaaga ctggtttagc tagtttttca
     1081 ccaatgactt ttacagtatc gcaagcacgg ccaccaccga ctgcaaacag gacgtctgct
     1141 ttttggacac tttcatgctg gatcaactgt tcaatatttc cataagttga attacccccg
     1201 taccagagac tggcgacaac ctctatttcc tgtgtcaaag ctacttttat tttgttttct
     1261 gcctttgaaa gtgcagtctt ccctccaatc agcactactt ttgtcccata ttctttgacg
     1321 attccatttg ctttttcata cgcatctgtt ccaatggtat aatttggtaa gaaaacactt
     1381 tgactcatat tcatttcctt ctttcttcgt tgaaacgggt taaaatttta aagagtgatc
     1441 gatctgactg cggctgtaga tggagtagag gtgaacctaa gacaggataa gtgatgaata
     1501 aggtggcatg aacaccttga aatcatcaat aagtatccta aaaacgaaca agtacaaaaa
     1561 cattgaaaac gacaataatg aatttttgtt cctcttagta tttctaccga ttccctttgc
     1621 ttttttgtaa ttatctaaaa attctaaaaa ttaagattat tatatgaaaa caggttttat
     1681 ttgtcaattc ataattggtt ttttttaaag caaaagataa tctatatcat gatgaacaaa
     1741 cagagttttt tcctccaatt gatggctttc ctgatctttc ctattttgaa taaagtgttt
     1801 ctgtataatt tttttatttt ataagtaaga taaataatga aagaatagag atactgattg
     1861 gtagctaaag atttttgagc gagaacattt cgttttttca aaaggactgt tagaataagc
     1921 aagaacaagg gggaagacgt atgataatca gtgaatttga ccgtaataat ccagtattga
     1981 aagatcagct ttctgattta ctgagactga cttggccgga agaatatgga gacagctcgg
     2041 cagaagaagt agaagaaatg atgaatccag aacgaatcgc ggtagcagcg gtagaccaag
     2101 atgagttagt aggatttatt ggtgcaatcc ctcaatacgg tatcacaggt tgggaattgc
     2161 atccattagt tgtagaaagc tcccgacgaa agaaccaaat aggtactcga ttagtcaatt
     2221 acttagaaaa agaagtagct tccagaggag gaatcacgat ttatttaggt acggatgatt
     2281 tagaccatgg aacaacgtta agtcaaacgg acctgtatga gcatacattt gataaagtgg
     2341 cttccatcca gaaccttcgt gaacatccgt atgaattcta tgaaaaatta ggttataaaa
     2401 tcgtaggtgt cttaccaaat gcaaatggct gggacaaacc ggatatttgg atggcaaaaa
     2461 cgattattcc tcgaccaaat tctcaataat aaaaagaggt tgtgacagaa gtaatcagct
     2521 tcaagaaata agaaggaatt tacgaaaatt actt
//
LOCUS       DAXLPY010000278         1660 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.176, whole genome shotgun sequence.
ACCESSION   DAXLPY010000278 DAXLPY010000000
VERSION     DAXLPY010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.176"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            complement(39..341)
                     /locus_tag="ACF3UF_002968"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="ACF3UF_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            434..783
                     /locus_tag="ACF3UF_002969"
                     /pseudo
     CDS             434..783
                     /locus_tag="ACF3UF_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1055..1345)
                     /locus_tag="ACF3UF_002970"
     CDS             complement(1055..1345)
                     /locus_tag="ACF3UF_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3672972.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1553..>1660)
                     /locus_tag="ACF3UF_002971"
     CDS             complement(1553..>1660)
                     /locus_tag="ACF3UF_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFD3672973.1"
                     /translation="NSSLKQYIQKLEKAKDEVEDTADKSQQIVEEHLRK"
BASE COUNT          520 a          319 c          227 g          594 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt ccaaaacaag
     1021 cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca tcttgtcgga
     1081 ccttttttct tgggtataga cttttctcat attctaccac aattttgggt ttccctaaca
     1141 catgatagga tctcacaaca aattgctttc tattattata ataacctgta acgactaact
     1201 tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc aaacaattga
     1261 ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta cggatcttat
     1321 ctactgttcc atattttttc tccataacct tcacctcaat accattatac gaacatacat
     1381 tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat tacctttctt
     1441 aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa agaggcagca
     1501 gtatagatta ctgttgcttc tttactaatt taggtttact tgttaagaaa gattatttac
     1561 gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt atcttccact tcatcttttg
     1621 ctttttctaa cttttgaata tattgtttca agcttgagtt
//
LOCUS       DAXLPY010000279         1537 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.184, whole genome shotgun sequence.
ACCESSION   DAXLPY010000279 DAXLPY010000000
VERSION     DAXLPY010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.184"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            <1..1418
                     /locus_tag="ACF3UF_002972"
                     /note="aph(2'')-Ia"
     CDS             <1..1418
                     /locus_tag="ACF3UF_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFD3672974.1"
                     /translation="CIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLESLKKHYTE
                     PWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSK
                     GIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGK
                     KEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFK
                     TKFSTDKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTP
                     EIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYND
                     LTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCSHLLLDGNNRLTGIIDFGDSGII
                     DEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
BASE COUNT          651 a          116 c          263 g          507 t
ORIGIN      
        1 tatgtataag aactttaata gatgatgatt ttcctttgat gttaaaatgg ttaactgatg
       61 aaagagtatt agaattttat gatggtagag ataaaaaata tacattagaa tcattaaaaa
      121 aacattatac agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg
      181 ttcctattgg atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt
      241 atccaaaaac tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt
      301 ggagtaaagg aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa
      361 gaaatgctaa tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat
      421 accaaaaatc tggttttaga attattgaag atttgccaga acatgaatta cacgagggca
      481 aaaaagaaga ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg
      541 caatgaaata tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa
      601 tcggtagtgg ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa
      661 aatttagtac tgataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa
      721 atacaaattt agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg
      781 aattatctat actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt
      841 ctactatgtc agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac
      901 aaatgcacgg tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg
      961 tattagaaga gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa
     1021 aagattatat agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa
     1081 agtgtttatg ccataatgat tttagttgta gtcatctatt gttagatggc aataatagat
     1141 taactggaat aattgatttt ggagattctg gaattataga tgaatattgt gattttatat
     1201 acttacttga agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa
     1261 tgtatggaaa tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt
     1321 atcctattga aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg
     1381 gtagaaaaga aatttataaa aggacttata aagattgatt atataatata tgaaaagcta
     1441 ttataaaaga cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaagtgagt
     1501 caagtccaga ctcctgtgta aaatgctata caatgtt
//
LOCUS       DAXLPY010000280          783 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.216, whole genome shotgun sequence.
ACCESSION   DAXLPY010000280 DAXLPY010000000
VERSION     DAXLPY010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.216"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            29..766
                     /gene="erm(B)"
                     /locus_tag="ACF3UF_002973"
     CDS             29..766
                     /gene="erm(B)"
                     /locus_tag="ACF3UF_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFD3672975.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          291 a          138 c          123 g          231 t
ORIGIN      
        1 tagatgtaat cacttcagga gtgataacat gaacaaaaat ataaaatatt ctcaaaactt
       61 tttaacgagt gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga
      121 taccgtttac gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag
      181 taaacaggta acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt
      241 aaaactgaat actcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa
      301 caaacagagg tataaaattg ttgggaatat tccttaccat ttaagcacac aaattattaa
      361 aaaagtggtt tttgaaagcc gtgcgtctga catctatctg attgttgaag aaggattcta
      421 caagcgtacc ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat
      481 tcagcaattg cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt
      541 cttaataaaa cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac
      601 gtactttgtt tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt
      661 tcatcaagca atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt
      721 attgtctatt tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct
      781 ttt
//
LOCUS       DAXLPY010000281          783 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2360
            SAMD00565575-rid20744723.guided.217, whole genome shotgun sequence.
ACCESSION   DAXLPY010000281 DAXLPY010000000
VERSION     DAXLPY010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565575
            Sequence Read Archive: DRR427961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054600.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054600.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:44:08
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,974
            CDSs (total)                      :: 2,908
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 49 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 17 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565575-rid20744723.guided.217"
                     /strain="JARB-OU2360"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-12-10"
                     /collected_by="Hiroshima"
     gene            29..766
                     /gene="erm(B)"
                     /locus_tag="ACF3UF_002974"
     CDS             29..766
                     /gene="erm(B)"
                     /locus_tag="ACF3UF_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFD3672976.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKYA
                     KVNDLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          290 a          137 c          124 g          232 t
ORIGIN      
        1 tagatgtaat cacttcagga gtgataacat gaacaaaaat ataaaatatt ctcaaaactt
       61 tttaacgagt gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga
      121 taccgtttac gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag
      181 taaacaggta acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt
      241 aaaactgaat actcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa
      301 caaacagagg tataaaattg ttgggaatat tccttaccat ttaagcacac aaattattaa
      361 aaaagtggtt tttgaaagcc gtgcgtctga catctatctg attgttgaag aaggattcta
      421 caagcgtacc ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat
      481 tcagcaattg cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt
      541 cttaataaaa cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac
      601 gtactttgtt tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt
      661 tcatcaagca atgaaatacg ccaaagtaaa cgatttaagt accgttactt atgagcaagt
      721 attgtctatt tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct
      781 ttt
//
